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Search of human proteins with 239758055
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239758055 PREDICTED: similar to tektin 4 [Homo sapiens]
(254 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239758055 PREDICTED: similar to tektin 4 [Homo sapiens] 516 e-147
gi|239747014 PREDICTED: similar to tektin 4 [Homo sapiens] 346 1e-95
gi|239752581 PREDICTED: MAFF interacting protein [Homo sapiens] 345 2e-95
gi|239747088 PREDICTED: MAFF interacting protein [Homo sapiens] 229 1e-60
gi|21389613 tektin 4 [Homo sapiens] 186 2e-47
gi|13994250 tektin 3 [Homo sapiens] 72 6e-13
gi|16753231 tektin 1 [Homo sapiens] 63 3e-10
gi|169209613 PREDICTED: hypothetical protein LOC100128785 [Homo ... 59 4e-09
gi|169210642 PREDICTED: hypothetical protein LOC100128785 [Homo ... 59 4e-09
gi|169210176 PREDICTED: hypothetical protein LOC100128785 [Homo ... 59 4e-09
gi|21389569 tektin 5 [Homo sapiens] 55 8e-08
gi|27894337 keratin 20 [Homo sapiens] 41 0.001
gi|67782365 keratin 7 [Homo sapiens] 38 0.007
gi|40538794 coiled-coil domain containing 21 [Homo sapiens] 38 0.007
gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Hom... 36 0.037
gi|31559829 keratin 25 [Homo sapiens] 35 0.063
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 35 0.082
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 35 0.082
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 35 0.082
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 35 0.082
gi|114431246 keratin 25D [Homo sapiens] 34 0.11
gi|94538345 keratin 35 [Homo sapiens] 34 0.14
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 34 0.14
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 33 0.18
gi|153945736 keratin 27 [Homo sapiens] 33 0.18
gi|32567786 keratin 6L [Homo sapiens] 33 0.24
gi|4504927 keratin 36 [Homo sapiens] 33 0.24
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 33 0.31
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 33 0.31
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 33 0.31
>gi|239758055 PREDICTED: similar to tektin 4 [Homo sapiens]
Length = 254
Score = 516 bits (1329), Expect = e-147
Identities = 254/254 (100%), Positives = 254/254 (100%)
Query: 1 MVQTDMLLPEPVPQTMPPCELPCKEYDAFANCNQSERELQGHESQQLAAETQALAQGTQQ 60
MVQTDMLLPEPVPQTMPPCELPCKEYDAFANCNQSERELQGHESQQLAAETQALAQGTQQ
Sbjct: 1 MVQTDMLLPEPVPQTMPPCELPCKEYDAFANCNQSERELQGHESQQLAAETQALAQGTQQ 60
Query: 61 DSTRRVGEQLQDTHSWKSELQREVEALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQ 120
DSTRRVGEQLQDTHSWKSELQREVEALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQ
Sbjct: 61 DSTRRVGEQLQDTHSWKSELQREVEALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQ 120
Query: 121 CSQGHQNANLMRDHVETELLKVPAAVGGQDLWVQRGGAPGSSCGQATWLLQAHRRPALCA 180
CSQGHQNANLMRDHVETELLKVPAAVGGQDLWVQRGGAPGSSCGQATWLLQAHRRPALCA
Sbjct: 121 CSQGHQNANLMRDHVETELLKVPAAVGGQDLWVQRGGAPGSSCGQATWLLQAHRRPALCA 180
Query: 181 SRKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHKKEAELIRNIQELLKRAIVQAV 240
SRKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHKKEAELIRNIQELLKRAIVQAV
Sbjct: 181 SRKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHKKEAELIRNIQELLKRAIVQAV 240
Query: 241 SQIRWVEGCPRDDS 254
SQIRWVEGCPRDDS
Sbjct: 241 SQIRWVEGCPRDDS 254
>gi|239747014 PREDICTED: similar to tektin 4 [Homo sapiens]
Length = 507
Score = 346 bits (887), Expect = 1e-95
Identities = 185/245 (75%), Positives = 197/245 (80%), Gaps = 25/245 (10%)
Query: 1 MVQTDMLLPEPVPQTMPPCELPCKEYD-AFANCNQSERELQGHESQQLAAETQALAQGTQ 59
MVQTDMLLPEP PQT+PPCELPCKEYD AFA+CNQSERELQGH+SQQLAAE QALAQ TQ
Sbjct: 1 MVQTDMLLPEPAPQTVPPCELPCKEYDVAFADCNQSERELQGHKSQQLAAEIQALAQPTQ 60
Query: 60 QDSTRRVGEQLQDTHSWKSELQREVEALAAETDLLLAQKQRLEHALDATEAPFSIATDNL 119
QDS RVGE+LQD HSW SELQ EVEALAAETDLLLAQKQRLEHALDA E PFSIATDN+
Sbjct: 61 QDSKCRVGERLQDMHSWNSELQGEVEALAAETDLLLAQKQRLEHALDAMEVPFSIATDNM 120
Query: 120 QCSQGHQNANLMRDHVETELLKVPAAVGGQDLWVQRGGAPGSSCGQATWLLQAHRRPALC 179
QC+Q HQ+ANL+RDHVETELLK Q L +C C
Sbjct: 121 QCNQRHQHANLVRDHVETELLKAYPPAPSQCL---------KNC---------------C 156
Query: 180 ASRKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHKKEAELIRNIQELLKRAIVQA 239
+SRKPSA NKG C+VMETLTVQEEANPGTEGCRTRALAHK+EAELIRNIQELLKR IVQA
Sbjct: 157 SSRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAELIRNIQELLKRVIVQA 216
Query: 240 VSQIR 244
VSQIR
Sbjct: 217 VSQIR 221
>gi|239752581 PREDICTED: MAFF interacting protein [Homo sapiens]
Length = 333
Score = 345 bits (886), Expect = 2e-95
Identities = 191/260 (73%), Positives = 196/260 (75%), Gaps = 55/260 (21%)
Query: 16 MPPCELPCKEYD-------------------------------AFANCNQSERELQGHES 44
MPPCELPCKEYD AFANCNQSE+ELQGHES
Sbjct: 1 MPPCELPCKEYDVARNTGTYMSSGLATAXLEVWFQNCYARYHQAFANCNQSEQELQGHES 60
Query: 45 QQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREVEALAAETDLLLAQKQRLEHA 104
QQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREVEALAAETDLLLAQKQRLEHA
Sbjct: 61 QQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREVEALAAETDLLLAQKQRLEHA 120
Query: 105 LDATEAPFSIATDNLQCSQGHQNANLMRDHVETELLKVPAAVGGQDLWVQRGGAPGSSCG 164
LDATEAPFSIATDNLQCSQGHQ+ANLMRDHVETELLK Q L ++C
Sbjct: 121 LDATEAPFSIATDNLQCSQGHQHANLMRDHVETELLKAHPPAPSQCL---------NNC- 170
Query: 165 QATWLLQAHRRPALCASRKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHKKEAEL 224
+SRKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHKKEAEL
Sbjct: 171 --------------FSSRKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHKKEAEL 216
Query: 225 IRNIQELLKRAIVQAVSQIR 244
IRNIQELLKRAIVQAVSQIR
Sbjct: 217 IRNIQELLKRAIVQAVSQIR 236
>gi|239747088 PREDICTED: MAFF interacting protein [Homo sapiens]
Length = 445
Score = 229 bits (585), Expect = 1e-60
Identities = 123/172 (71%), Positives = 130/172 (75%), Gaps = 31/172 (18%)
Query: 1 MVQTDMLLPEPVPQTMPPCELPCKEYD-------------------------------AF 29
MVQTD+LLPE PQT+PP ELPCKEYD AF
Sbjct: 1 MVQTDVLLPELAPQTVPPYELPCKEYDVARNTGAYTSSGLATAXLEVWFQNCYARYRQAF 60
Query: 30 ANCNQSERELQGHESQQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREVEALAA 89
ANCNQSERELQGHESQQLAAETQALAQ TQQDST RVGE+LQDT+SWKSELQREVEALAA
Sbjct: 61 ANCNQSERELQGHESQQLAAETQALAQPTQQDSTCRVGERLQDTNSWKSELQREVEALAA 120
Query: 90 ETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVETELLK 141
ETDLLLAQKQRLE ALDA E PFSI TDN+QCSQ HQ+ NL+RDHVETELLK
Sbjct: 121 ETDLLLAQKQRLERALDAMEVPFSITTDNMQCSQRHQHTNLLRDHVETELLK 172
>gi|21389613 tektin 4 [Homo sapiens]
Length = 435
Score = 186 bits (471), Expect = 2e-47
Identities = 104/166 (62%), Positives = 114/166 (68%), Gaps = 40/166 (24%)
Query: 14 QTMPPCELPCKEYD--------------------------------------AFANCNQS 35
QT+PPCELPCKEYD AFA+ +QS
Sbjct: 3 QTVPPCELPCKEYDVARNTGAYTSSGLATASFRTSKYLLEEWFQNCYARYHQAFADRDQS 62
Query: 36 ERELQGHESQQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREVEALAAETDLLL 95
ER Q HESQQLA ETQALAQ TQQDSTR VGE+LQDTHSWKSELQRE+EALAAET+LLL
Sbjct: 63 ER--QRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLL 120
Query: 96 AQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVETELLK 141
AQKQRLE ALDATE PFSI TDNLQC + ++ NL+RDHVETELLK
Sbjct: 121 AQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLK 166
>gi|13994250 tektin 3 [Homo sapiens]
Length = 490
Score = 71.6 bits (174), Expect = 6e-13
Identities = 41/115 (35%), Positives = 61/115 (53%), Gaps = 7/115 (6%)
Query: 33 NQSERELQGHESQQLAAETQALAQG-------TQQDSTRRVGEQLQDTHSWKSELQREVE 85
N E H S++L +T L Q TQ D+T+ +GE++ D WKSE+ E++
Sbjct: 106 NYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELD 165
Query: 86 ALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVETELL 140
+ ET+ L K+RLE AL TEAP +A + L + +L+ D VE +LL
Sbjct: 166 EMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLL 220
>gi|16753231 tektin 1 [Homo sapiens]
Length = 418
Score = 62.8 bits (151), Expect = 3e-10
Identities = 46/140 (32%), Positives = 70/140 (50%), Gaps = 10/140 (7%)
Query: 17 PPCELPCKEYDAFANCNQSER-ELQGHESQQLAAETQALA-------QGTQQDSTRRVGE 68
PP LP + + AN NQ R + Q S++L AE+Q L + +Q D +++ +
Sbjct: 8 PPKFLPSEWH--IANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQ 65
Query: 69 QLQDTHSWKSELQREVEALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNA 128
+L++ WK EL ++E L TD LL K RLE AL+ + P I L +
Sbjct: 66 RLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGI 125
Query: 129 NLMRDHVETELLKVPAAVGG 148
+L+ D VE EL+K + G
Sbjct: 126 DLVHDTVEHELIKEAEIIQG 145
Score = 28.9 bits (63), Expect = 4.5
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 189 KGPCQVMETLTVQEEANPGTEGCRTRALAHK--KEAELIRNIQELLKRAIVQAVSQIR 244
K P + ET E G + + H+ KEAE+I+ I LL R + +A QIR
Sbjct: 106 KEPLHITETCLAYREKRIGIDLVHD-TVEHELIKEAEIIQGIMALLTRTLEEASEQIR 162
Score = 28.1 bits (61), Expect = 7.7
Identities = 27/131 (20%), Positives = 49/131 (37%), Gaps = 7/131 (5%)
Query: 18 PCELPCKEYDAFANCNQSERELQGHESQQLAAETQALAQGTQQDSTRRVG-------EQL 70
P + +++ F++ N + + Q + S L A + T D ++ L
Sbjct: 209 PNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGL 268
Query: 71 QDTHSWKSELQREVEALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANL 130
+DT + +L + + E LE A+ E P +A L+ N L
Sbjct: 269 KDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVEL 328
Query: 131 MRDHVETELLK 141
RD + L+K
Sbjct: 329 CRDVAQYRLMK 339
>gi|169209613 PREDICTED: hypothetical protein LOC100128785 [Homo
sapiens]
Length = 639
Score = 58.9 bits (141), Expect = 4e-09
Identities = 49/145 (33%), Positives = 66/145 (45%), Gaps = 34/145 (23%)
Query: 100 RLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVETELLKVPAAVGGQDLWVQRGGAP 159
+L HA D PFSIAT+NLQ + + L+ D+VETELLKV GGQD
Sbjct: 303 QLCHASDTMTVPFSIATNNLQYHEQCWHPYLVGDYVETELLKVLRPRGGQDC-------- 354
Query: 160 GSSCGQATWLLQAHRRPALCASRKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHK 219
P R P ++ L+V++ G + R L
Sbjct: 355 ------------------------PLLRTLCPFRIQHDLSVKQPRRVPGSGAQGRLLI-- 388
Query: 220 KEAELIRNIQELLKRAIVQAVSQIR 244
+EAELI +I ELL+R VQA ++ R
Sbjct: 389 QEAELIGSIPELLERPTVQAGNRSR 413
>gi|169210642 PREDICTED: hypothetical protein LOC100128785 [Homo
sapiens]
Length = 639
Score = 58.9 bits (141), Expect = 4e-09
Identities = 49/145 (33%), Positives = 66/145 (45%), Gaps = 34/145 (23%)
Query: 100 RLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVETELLKVPAAVGGQDLWVQRGGAP 159
+L HA D PFSIAT+NLQ + + L+ D+VETELLKV GGQD
Sbjct: 303 QLCHASDTMTVPFSIATNNLQYHEQCWHPYLVGDYVETELLKVLRPRGGQDC-------- 354
Query: 160 GSSCGQATWLLQAHRRPALCASRKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHK 219
P R P ++ L+V++ G + R L
Sbjct: 355 ------------------------PLLRTLCPFRIQHDLSVKQPRRVPGSGAQGRLLI-- 388
Query: 220 KEAELIRNIQELLKRAIVQAVSQIR 244
+EAELI +I ELL+R VQA ++ R
Sbjct: 389 QEAELIGSIPELLERPTVQAGNRSR 413
>gi|169210176 PREDICTED: hypothetical protein LOC100128785 [Homo
sapiens]
Length = 639
Score = 58.9 bits (141), Expect = 4e-09
Identities = 49/145 (33%), Positives = 66/145 (45%), Gaps = 34/145 (23%)
Query: 100 RLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVETELLKVPAAVGGQDLWVQRGGAP 159
+L HA D PFSIAT+NLQ + + L+ D+VETELLKV GGQD
Sbjct: 303 QLCHASDTMTVPFSIATNNLQYHEQCWHPYLVGDYVETELLKVLRPRGGQDC-------- 354
Query: 160 GSSCGQATWLLQAHRRPALCASRKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHK 219
P R P ++ L+V++ G + R L
Sbjct: 355 ------------------------PLLRTLCPFRIQHDLSVKQPRRVPGSGAQGRLLI-- 388
Query: 220 KEAELIRNIQELLKRAIVQAVSQIR 244
+EAELI +I ELL+R VQA ++ R
Sbjct: 389 QEAELIGSIPELLERPTVQAGNRSR 413
>gi|21389569 tektin 5 [Homo sapiens]
Length = 485
Score = 54.7 bits (130), Expect = 8e-08
Identities = 30/99 (30%), Positives = 50/99 (50%)
Query: 43 ESQQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREVEALAAETDLLLAQKQRLE 102
+S +L + L Q+ + R +G++L D WKSEL E++ L E L K+RLE
Sbjct: 118 DSMRLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLETVKRRLE 177
Query: 103 HALDATEAPFSIATDNLQCSQGHQNANLMRDHVETELLK 141
A + P +A + L + +L+ D+VE L++
Sbjct: 178 CAANEVNCPLQVALECLYHREKRIGIDLVHDNVEKNLIR 216
Score = 31.6 bits (70), Expect = 0.70
Identities = 29/124 (23%), Positives = 51/124 (41%), Gaps = 17/124 (13%)
Query: 29 FANCNQSERELQGHESQQLAAETQALAQGTQQDSTRRVGE-------QLQDTHSWKSELQ 81
F+N N + S QL E + L + R+ + ++ + K++LQ
Sbjct: 298 FSNDNIKHSQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQ 357
Query: 82 REV-----EALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVE 136
++ E AE ++L LE ++ A E P +A L+C N L RD +
Sbjct: 358 TQLAKTLQEIFQAENTIML-----LERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIPQ 412
Query: 137 TELL 140
+L+
Sbjct: 413 LKLV 416
>gi|27894337 keratin 20 [Homo sapiens]
Length = 424
Score = 40.8 bits (94), Expect = 0.001
Identities = 31/109 (28%), Positives = 51/109 (46%), Gaps = 11/109 (10%)
Query: 24 KEYDAFANCNQSERELQGHESQQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQRE 83
++Y+ A N E + +Q +T L Q ++ E+L+ T +EL+R
Sbjct: 244 QKYEVMAQKNLQEAK------EQFERQTAVLQQQVTVNT-----EELKGTEVQLTELRRT 292
Query: 84 VEALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMR 132
++L E L+ K+ LEH L+ T+A +S NLQ A LM+
Sbjct: 293 SQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQ 341
>gi|67782365 keratin 7 [Homo sapiens]
Length = 469
Score = 38.1 bits (87), Expect = 0.007
Identities = 27/108 (25%), Positives = 48/108 (44%), Gaps = 11/108 (10%)
Query: 25 EYDAFANCNQSERELQGHESQQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREV 84
+Y+ A C+++E E + T Q + G+ L++T + SE+ R +
Sbjct: 267 QYEEMAKCSRAEAEAWYQTKFE-----------TLQAQAGKHGDDLRNTRNEISEMNRAI 315
Query: 85 EALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMR 132
+ L AE D + Q+ +LE A+ E +A + + Q A L R
Sbjct: 316 QRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQR 363
>gi|40538794 coiled-coil domain containing 21 [Homo sapiens]
Length = 762
Score = 38.1 bits (87), Expect = 0.007
Identities = 30/108 (27%), Positives = 50/108 (46%), Gaps = 3/108 (2%)
Query: 34 QSERELQGHESQQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQR---EVEALAAE 90
Q E E + Q++ + LA + ++ +QL+D+ +ELQ E+E+L E
Sbjct: 463 QKESEQNREKQQRIETLERYLADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEE 522
Query: 91 TDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVETE 138
T + +K+ +L EA FS A +LQ Q + + VE E
Sbjct: 523 TQAICREKEIQLESLRQREAEFSSAGHSLQDKQSVEETSGEGPEVEME 570
>gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Homo
sapiens]
Length = 1551
Score = 35.8 bits (81), Expect = 0.037
Identities = 46/199 (23%), Positives = 76/199 (38%), Gaps = 53/199 (26%)
Query: 17 PPCELPCKEYDAFANCNQSEREL-QGHESQQLAAETQALAQGTQQD-------------- 61
PP P ++ D ++ REL +G Q + AQG Q++
Sbjct: 476 PPAGSPGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAA 535
Query: 62 ---STRRVGEQLQDTHSWKSELQREVEALAAETDLLLAQ-KQRLEHALDATEAPFSIATD 117
TR + QL++ + + EL+ +V +L+ + L Q +QRLE + A + T+
Sbjct: 536 TASQTRALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETN 595
Query: 118 NLQCSQGHQNANLMRDHVETELLKVPAAVGGQDLWVQRGGAPGSSCGQATWLLQAHRRPA 177
+ +G E +L K AA+ Q L QAH
Sbjct: 596 GMGPPEGGPQ--------EAQLRKEVAALREQ-------------------LEQAH---- 624
Query: 178 LCASRKPSARNKGPCQVME 196
S +PS + + CQ+ E
Sbjct: 625 ---SHRPSGKEEALCQLQE 640
Score = 28.5 bits (62), Expect = 5.9
Identities = 43/185 (23%), Positives = 72/185 (38%), Gaps = 29/185 (15%)
Query: 73 THSWKSELQREVEALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMR 132
+ +W + L+R+++ L E L + Q HA TD+ + Q + +R
Sbjct: 409 SEAWAA-LERKLQCLEQEKVELSRKHQEALHA----------PTDHRELEQLRKEVQTLR 457
Query: 133 DHVETELLKVPAAVGGQDLWVQRGGAPGSSCGQATWLLQ---------AHRRPALCASRK 183
D + E+L+ A++ D G P S GQ + L Q A R L A +
Sbjct: 458 DRLP-EMLRDKASLSQTD------GPPAGSPGQDSDLRQELDRLHRELAEGRAGLQAQEQ 510
Query: 184 PSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHKKEAELIRNIQELLKRAIVQAVSQI 243
R +G Q E L +EA ++ A + E R Q L+ + Q+
Sbjct: 511 ELCRAQG--QQEELLQRLQEAQEREAATASQTRALSSQLEEARAAQRELEAQVSSLSRQV 568
Query: 244 RWVEG 248
++G
Sbjct: 569 TQLQG 573
>gi|31559829 keratin 25 [Homo sapiens]
Length = 450
Score = 35.0 bits (79), Expect = 0.063
Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 14/106 (13%)
Query: 47 LAAETQALAQGTQQDST-----------RRVGEQLQDTHSWKSEL---QREVEALAAETD 92
+ AE +ALA+ ++D+ +++ E + T S ++EL +R ++ L E
Sbjct: 255 MRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIELQ 314
Query: 93 LLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVETE 138
LLA K LE +L TE+ + +Q G L + ETE
Sbjct: 315 SLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETE 360
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 34.7 bits (78), Expect = 0.082
Identities = 57/251 (22%), Positives = 99/251 (39%), Gaps = 36/251 (14%)
Query: 7 LLPEPV---PQTMPPCELPCKEYDAF-ANCNQSERELQGHESQQLAAETQALAQGTQQDS 62
++P PV P +PP P KE + A E +L+ ++ AE +A + ++
Sbjct: 61 IIPTPVLTSPGAVPPLPSPSKEEEGLRAQVRDLEEKLETLRLKR--AEDKAKLKELEKHK 118
Query: 63 TRRVGEQLQDTHSWKSELQ--------REVEALAAETDLLLAQKQRLEHALDATEAPFSI 114
QL+ WKS++Q R EA + L A+++ +E D +A I
Sbjct: 119 I-----QLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADA---I 170
Query: 115 ATDNLQCSQGHQNANLMRDHVETELLKVPAAVGGQDLWVQRGGAPGSSCGQATWLLQAHR 174
L + A ++ VE +V ++ GS +++ L+
Sbjct: 171 EMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLK--- 227
Query: 175 RPALCASRKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHKK--EAELIRNIQELL 232
+ +AR K M L+ E+ E + + L KK E E++R +E L
Sbjct: 228 -----QLEEQNARLKDALVRMRDLSSSEK----QEHVKLQKLMEKKNQELEVVRQQRERL 278
Query: 233 KRAIVQAVSQI 243
+ + QA S I
Sbjct: 279 QEELSQAESTI 289
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 34.7 bits (78), Expect = 0.082
Identities = 57/251 (22%), Positives = 99/251 (39%), Gaps = 36/251 (14%)
Query: 7 LLPEPV---PQTMPPCELPCKEYDAF-ANCNQSERELQGHESQQLAAETQALAQGTQQDS 62
++P PV P +PP P KE + A E +L+ ++ AE +A + ++
Sbjct: 175 IIPTPVLTSPGAVPPLPSPSKEEEGLRAQVRDLEEKLETLRLKR--AEDKAKLKELEKHK 232
Query: 63 TRRVGEQLQDTHSWKSELQ--------REVEALAAETDLLLAQKQRLEHALDATEAPFSI 114
QL+ WKS++Q R EA + L A+++ +E D +A I
Sbjct: 233 I-----QLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADA---I 284
Query: 115 ATDNLQCSQGHQNANLMRDHVETELLKVPAAVGGQDLWVQRGGAPGSSCGQATWLLQAHR 174
L + A ++ VE +V ++ GS +++ L+
Sbjct: 285 EMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLK--- 341
Query: 175 RPALCASRKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHKK--EAELIRNIQELL 232
+ +AR K M L+ E+ E + + L KK E E++R +E L
Sbjct: 342 -----QLEEQNARLKDALVRMRDLSSSEK----QEHVKLQKLMEKKNQELEVVRQQRERL 392
Query: 233 KRAIVQAVSQI 243
+ + QA S I
Sbjct: 393 QEELSQAESTI 403
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 34.7 bits (78), Expect = 0.082
Identities = 57/251 (22%), Positives = 99/251 (39%), Gaps = 36/251 (14%)
Query: 7 LLPEPV---PQTMPPCELPCKEYDAF-ANCNQSERELQGHESQQLAAETQALAQGTQQDS 62
++P PV P +PP P KE + A E +L+ ++ AE +A + ++
Sbjct: 61 IIPTPVLTSPGAVPPLPSPSKEEEGLRAQVRDLEEKLETLRLKR--AEDKAKLKELEKHK 118
Query: 63 TRRVGEQLQDTHSWKSELQ--------REVEALAAETDLLLAQKQRLEHALDATEAPFSI 114
QL+ WKS++Q R EA + L A+++ +E D +A I
Sbjct: 119 I-----QLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADA---I 170
Query: 115 ATDNLQCSQGHQNANLMRDHVETELLKVPAAVGGQDLWVQRGGAPGSSCGQATWLLQAHR 174
L + A ++ VE +V ++ GS +++ L+
Sbjct: 171 EMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLK--- 227
Query: 175 RPALCASRKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHKK--EAELIRNIQELL 232
+ +AR K M L+ E+ E + + L KK E E++R +E L
Sbjct: 228 -----QLEEQNARLKDALVRMRDLSSSEK----QEHVKLQKLMEKKNQELEVVRQQRERL 278
Query: 233 KRAIVQAVSQI 243
+ + QA S I
Sbjct: 279 QEELSQAESTI 289
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 34.7 bits (78), Expect = 0.082
Identities = 57/251 (22%), Positives = 99/251 (39%), Gaps = 36/251 (14%)
Query: 7 LLPEPV---PQTMPPCELPCKEYDAF-ANCNQSERELQGHESQQLAAETQALAQGTQQDS 62
++P PV P +PP P KE + A E +L+ ++ AE +A + ++
Sbjct: 195 IIPTPVLTSPGAVPPLPSPSKEEEGLRAQVRDLEEKLETLRLKR--AEDKAKLKELEKHK 252
Query: 63 TRRVGEQLQDTHSWKSELQ--------REVEALAAETDLLLAQKQRLEHALDATEAPFSI 114
QL+ WKS++Q R EA + L A+++ +E D +A I
Sbjct: 253 I-----QLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADA---I 304
Query: 115 ATDNLQCSQGHQNANLMRDHVETELLKVPAAVGGQDLWVQRGGAPGSSCGQATWLLQAHR 174
L + A ++ VE +V ++ GS +++ L+
Sbjct: 305 EMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLK--- 361
Query: 175 RPALCASRKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHKK--EAELIRNIQELL 232
+ +AR K M L+ E+ E + + L KK E E++R +E L
Sbjct: 362 -----QLEEQNARLKDALVRMRDLSSSEK----QEHVKLQKLMEKKNQELEVVRQQRERL 412
Query: 233 KRAIVQAVSQI 243
+ + QA S I
Sbjct: 413 QEELSQAESTI 423
>gi|114431246 keratin 25D [Homo sapiens]
Length = 464
Score = 34.3 bits (77), Expect = 0.11
Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 11/114 (9%)
Query: 25 EYDAFANCNQSERELQGHESQQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREV 84
EY+A A N+ + E +E ++ +L Q DS + Q T E++R +
Sbjct: 265 EYEALAEQNRKDAEAWFNE------KSASLQQQISHDSGAATFARSQLT-----EMRRTL 313
Query: 85 EALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVETE 138
+ L + L+A K LE +L TE+ + +Q G L + ETE
Sbjct: 314 QTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETE 367
>gi|94538345 keratin 35 [Homo sapiens]
Length = 455
Score = 33.9 bits (76), Expect = 0.14
Identities = 23/71 (32%), Positives = 31/71 (43%)
Query: 68 EQLQDTHSWKSELQREVEALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQN 127
EQLQ + EL+R V AL E + + LE L TEA +S +QC +
Sbjct: 304 EQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVE 363
Query: 128 ANLMRDHVETE 138
A L + E
Sbjct: 364 AQLAEIRADLE 374
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 33.9 bits (76), Expect = 0.14
Identities = 44/200 (22%), Positives = 79/200 (39%), Gaps = 9/200 (4%)
Query: 34 QSERELQGHESQQLAAETQ-ALAQGTQQDSTRRVGEQLQDTHSWKSELQREVEALAAETD 92
Q + E+ S+ L E Q A G ++ + E+L D ++LQ ++ L +
Sbjct: 411 QLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLK 470
Query: 93 LLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVETELLKVPAAVGGQDLW 152
+ L+H LD T+ Q Q A L + +L +V +G +D
Sbjct: 471 EKVTNSTELQHQLDKTKQQH----QEQQALQQSTTAKLR--EAQNDLEQVLRQIGDKDQK 524
Query: 153 VQRGGAPGSSCGQATWLLQAHRRPALCASRKPSARNKGPCQVME-TLTVQEEANPGTEGC 211
+Q A + LL+ R + Q+ E T+QE+ TE
Sbjct: 525 IQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKL 584
Query: 212 RTRALAHKKEAELIRN-IQE 230
+ ++ +HK+ E + + +QE
Sbjct: 585 KNQSESHKQAQENLHDQVQE 604
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 33.5 bits (75), Expect = 0.18
Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 8/108 (7%)
Query: 36 ERELQGHESQQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREVEALAAETDLLL 95
E EL +QLAAE + T Q QLQ+ ++EL E E L A L
Sbjct: 851 EEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRAR---LT 907
Query: 96 AQKQRLEHALDATEAPFSIATDNLQCSQG-----HQNANLMRDHVETE 138
A+KQ LE EA + Q Q QN + + +E E
Sbjct: 908 AKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEE 955
>gi|153945736 keratin 27 [Homo sapiens]
Length = 459
Score = 33.5 bits (75), Expect = 0.18
Identities = 30/106 (28%), Positives = 50/106 (47%), Gaps = 14/106 (13%)
Query: 47 LAAETQALAQGTQQDS-------TRRVGEQLQD----THSWKSEL---QREVEALAAETD 92
+ AE +ALA+ ++D+ + + +Q+ D T S ++EL +R ++ L E
Sbjct: 260 MRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQ 319
Query: 93 LLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVETE 138
LLA K LE +L TE+ + +Q G L + ETE
Sbjct: 320 SLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETE 365
>gi|32567786 keratin 6L [Homo sapiens]
Length = 535
Score = 33.1 bits (74), Expect = 0.24
Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 13/112 (11%)
Query: 44 SQQLAAETQALAQGTQQD---STRRVGEQLQDTHSWKSELQREVEALAAETDLLLAQKQR 100
+Q+ AE +A Q ++ + + G+ L+DT + +EL R ++ L E D Q Q+
Sbjct: 326 AQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQ 385
Query: 101 LEHALDATEAPFSIATDNLQCSQG------HQN----ANLMRDHVETELLKV 142
L+ A+ E +A + Q G HQ L+RD+ E +K+
Sbjct: 386 LQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKL 437
>gi|4504927 keratin 36 [Homo sapiens]
Length = 467
Score = 33.1 bits (74), Expect = 0.24
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Query: 68 EQLQDTHSWKSELQREVEALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQN 127
EQLQ + EL+R V AL E + + LE L TEA +S +QC +
Sbjct: 300 EQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVE 359
Query: 128 ANLMRDHVETE--------LLKVPAAVGGQ 149
A L + E LL V A + G+
Sbjct: 360 AQLSEIRCDLERQNQEYQVLLDVKARLEGE 389
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 32.7 bits (73), Expect = 0.31
Identities = 51/220 (23%), Positives = 88/220 (40%), Gaps = 28/220 (12%)
Query: 27 DAFANCNQSERELQGHESQQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREVEA 86
+ F+ +SE+ L+G E++ L + + A D RR +Q +D E+ EV
Sbjct: 1695 EIFSQNRESEKRLKGLEAEVLRLQEELAA----SDRARRQAQQDRD------EMADEVAN 1744
Query: 87 LAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVETELLKVPAAV 146
+L +K++LE L E + + N+ L+ D LL+V +
Sbjct: 1745 GNLSKAAILEEKRQLEGRLGQLEE---------ELEEEQSNSELLNDRYRKLLLQVESLT 1795
Query: 147 GGQDLWVQRGGAPGSSCG--QATWLLQAHRRPALCASRKPSARNKGPCQVMETLTVQEEA 204
+L +R + + G Q +Q R AR+K +E+ Q E
Sbjct: 1796 --TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEE 1853
Query: 205 NPGTEGCRTRALAHKKEAELIRNIQELLKRAIVQAVSQIR 244
E R R L+ K L+R ++ LK ++Q + R
Sbjct: 1854 QLEQE-TRERILSGK----LVRRAEKRLKEVVLQVEEERR 1888
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 32.7 bits (73), Expect = 0.31
Identities = 51/220 (23%), Positives = 88/220 (40%), Gaps = 28/220 (12%)
Query: 27 DAFANCNQSERELQGHESQQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREVEA 86
+ F+ +SE+ L+G E++ L + + A D RR +Q +D E+ EV
Sbjct: 1687 EIFSQNRESEKRLKGLEAEVLRLQEELAA----SDRARRQAQQDRD------EMADEVAN 1736
Query: 87 LAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVETELLKVPAAV 146
+L +K++LE L E + + N+ L+ D LL+V +
Sbjct: 1737 GNLSKAAILEEKRQLEGRLGQLEE---------ELEEEQSNSELLNDRYRKLLLQVESLT 1787
Query: 147 GGQDLWVQRGGAPGSSCG--QATWLLQAHRRPALCASRKPSARNKGPCQVMETLTVQEEA 204
+L +R + + G Q +Q R AR+K +E+ Q E
Sbjct: 1788 --TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEE 1845
Query: 205 NPGTEGCRTRALAHKKEAELIRNIQELLKRAIVQAVSQIR 244
E R R L+ K L+R ++ LK ++Q + R
Sbjct: 1846 QLEQE-TRERILSGK----LVRRAEKRLKEVVLQVEEERR 1880
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 32.7 bits (73), Expect = 0.31
Identities = 51/220 (23%), Positives = 88/220 (40%), Gaps = 28/220 (12%)
Query: 27 DAFANCNQSERELQGHESQQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREVEA 86
+ F+ +SE+ L+G E++ L + + A D RR +Q +D E+ EV
Sbjct: 1728 EIFSQNRESEKRLKGLEAEVLRLQEELAA----SDRARRQAQQDRD------EMADEVAN 1777
Query: 87 LAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVETELLKVPAAV 146
+L +K++LE L E + + N+ L+ D LL+V +
Sbjct: 1778 GNLSKAAILEEKRQLEGRLGQLEE---------ELEEEQSNSELLNDRYRKLLLQVESLT 1828
Query: 147 GGQDLWVQRGGAPGSSCG--QATWLLQAHRRPALCASRKPSARNKGPCQVMETLTVQEEA 204
+L +R + + G Q +Q R AR+K +E+ Q E
Sbjct: 1829 --TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEE 1886
Query: 205 NPGTEGCRTRALAHKKEAELIRNIQELLKRAIVQAVSQIR 244
E R R L+ K L+R ++ LK ++Q + R
Sbjct: 1887 QLEQE-TRERILSGK----LVRRAEKRLKEVVLQVEEERR 1921
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.127 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,603,802
Number of Sequences: 37866
Number of extensions: 471145
Number of successful extensions: 2185
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 87
Number of HSP's that attempted gapping in prelim test: 2021
Number of HSP's gapped (non-prelim): 259
length of query: 254
length of database: 18,247,518
effective HSP length: 100
effective length of query: 154
effective length of database: 14,460,918
effective search space: 2226981372
effective search space used: 2226981372
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.