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Search of human proteins with 239757877
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
(1662 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo s... 3251 0.0
gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 3106 0.0
gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 3106 0.0
gi|211971072 FERM and PDZ domain containing 4 [Homo sapiens] 351 3e-96
gi|239582741 FERM and PDZ domain containing 1 [Homo sapiens] 201 6e-51
gi|4507379 TATA box binding protein [Homo sapiens] 64 9e-10
gi|40354197 THAP domain containing 11 [Homo sapiens] 64 2e-09
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 63 3e-09
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 63 3e-09
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 63 3e-09
gi|110347429 mediator complex subunit 12 [Homo sapiens] 62 6e-09
gi|33286444 mastermind-like 2 [Homo sapiens] 61 1e-08
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens] 60 1e-08
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 60 2e-08
gi|55956910 meningioma 1 [Homo sapiens] 60 2e-08
gi|189491748 ataxin 1 [Homo sapiens] 59 3e-08
gi|51479158 ataxin 1 [Homo sapiens] 59 3e-08
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 59 3e-08
gi|226442791 runt-related transcription factor 2 isoform b [Homo... 59 4e-08
gi|226442783 runt-related transcription factor 2 isoform a [Homo... 59 4e-08
gi|66934969 runt-related transcription factor 2 isoform c [Homo ... 59 4e-08
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa... 59 5e-08
gi|56549696 E1A binding protein p400 [Homo sapiens] 59 5e-08
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens] 58 7e-08
gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens] 58 7e-08
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 57 1e-07
gi|38158015 mastermind-like 3 [Homo sapiens] 57 2e-07
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 56 3e-07
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 56 3e-07
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 56 3e-07
>gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1662
Score = 3251 bits (8428), Expect = 0.0
Identities = 1662/1662 (100%), Positives = 1662/1662 (100%)
Query: 1 MQEESANDMECEQLPAEILRQVTVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAG 60
MQEESANDMECEQLPAEILRQVTVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAG
Sbjct: 1 MQEESANDMECEQLPAEILRQVTVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAG 60
Query: 61 DQIVAINEEDVSEAPRERLIELIRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVK 120
DQIVAINEEDVSEAPRERLIELIRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVK
Sbjct: 61 DQIVAINEEDVSEAPRERLIELIRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVK 120
Query: 121 VRFSEQVAVGETDAKMMKKEALLLIPNVLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRL 180
VRFSEQVAVGETDAKMMKKEALLLIPNVLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRL
Sbjct: 121 VRFSEQVAVGETDAKMMKKEALLLIPNVLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRL 180
Query: 181 SLRFIEHFALVLEYAGPEQNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVEL 240
SLRFIEHFALVLEYAGPEQNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVEL
Sbjct: 181 SLRFIEHFALVLEYAGPEQNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVEL 240
Query: 241 LRRDPAAFEYLYIQXXXXXXXXIKEKNLRKSLSQQLKAHQTHPSCGTKGSAIQAKLQYLR 300
LRRDPAAFEYLYIQ IKEKNLRKSLSQQLKAHQTHPSCGTKGSAIQAKLQYLR
Sbjct: 241 LRRDPAAFEYLYIQXXXXXXXXIKEKNLRKSLSQQLKAHQTHPSCGTKGSAIQAKLQYLR 300
Query: 301 ILNELPTFTGVLFNTVGLDEKQSATTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQL 360
ILNELPTFTGVLFNTVGLDEKQSATTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQL
Sbjct: 301 ILNELPTFTGVLFNTVGLDEKQSATTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQL 360
Query: 361 FRENQGVARVETSIMDAKPLVLLMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLP 420
FRENQGVARVETSIMDAKPLVLLMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLP
Sbjct: 361 FRENQGVARVETSIMDAKPLVLLMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLP 420
Query: 421 PPMIKADYMHSAHRPVTGGHLGKKESSYVGSVGTSPRKSSRCTPPPADSELVSFCYLHMR 480
PPMIKADYMHSAHRPVTGGHLGKKESSYVGSVGTSPRKSSRCTPPPADSELVSFCYLHMR
Sbjct: 421 PPMIKADYMHSAHRPVTGGHLGKKESSYVGSVGTSPRKSSRCTPPPADSELVSFCYLHMR 480
Query: 481 EQRKEQESRTDVNENLIFFEETRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRA 540
EQRKEQESRTDVNENLIFFEETRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRA
Sbjct: 481 EQRKEQESRTDVNENLIFFEETRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRA 540
Query: 541 RSYTLDNSLGAEALNFYCDSCKAKLQSSXGPSQSGKPGSSRDNILLYDEIPVTLIDSVQT 600
RSYTLDNSLGAEALNFYCDSCKAKLQSS GPSQSGKPGSSRDNILLYDEIPVTLIDSVQT
Sbjct: 541 RSYTLDNSLGAEALNFYCDSCKAKLQSSXGPSQSGKPGSSRDNILLYDEIPVTLIDSVQT 600
Query: 601 RTVRDHAQELDDALVSTLQALEALAASEDGPHPPPPQTAGLIVLATITPESSLDSGHETN 660
RTVRDHAQELDDALVSTLQALEALAASEDGPHPPPPQTAGLIVLATITPESSLDSGHETN
Sbjct: 601 RTVRDHAQELDDALVSTLQALEALAASEDGPHPPPPQTAGLIVLATITPESSLDSGHETN 660
Query: 661 SSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQAVLTAPYSLGR 720
SSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQAVLTAPYSLGR
Sbjct: 661 SSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQAVLTAPYSLGR 720
Query: 721 PDPNPSLQPIATGQSPGPPGARRKLPQSEGQVQGERTYSLAVHPALSPQLSEQKNLSLLS 780
PDPNPSLQPIATGQSPGPPGARRKLPQSEGQVQGERTYSLAVHPALSPQLSEQKNLSLLS
Sbjct: 721 PDPNPSLQPIATGQSPGPPGARRKLPQSEGQVQGERTYSLAVHPALSPQLSEQKNLSLLS 780
Query: 781 PVPEDKGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRLSPKLILDPKSSVTPAI 840
PVPEDKGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRLSPKLILDPKSSVTPAI
Sbjct: 781 PVPEDKGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRLSPKLILDPKSSVTPAI 840
Query: 841 ISAALQQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSA 900
ISAALQQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSA
Sbjct: 841 ISAALQQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSA 900
Query: 901 PETSWNSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGK 960
PETSWNSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGK
Sbjct: 901 PETSWNSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGK 960
Query: 961 QATGEVAGKGGPVGGKPTLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQS 1020
QATGEVAGKGGPVGGKPTLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQS
Sbjct: 961 QATGEVAGKGGPVGGKPTLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQS 1020
Query: 1021 PSCQSRSHSPSCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLN 1080
PSCQSRSHSPSCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLN
Sbjct: 1021 PSCQSRSHSPSCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLN 1080
Query: 1081 GAHSTSEGPAKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLK 1140
GAHSTSEGPAKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLK
Sbjct: 1081 GAHSTSEGPAKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLK 1140
Query: 1141 PPSQGELPGTEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGRPQATQT 1200
PPSQGELPGTEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGRPQATQT
Sbjct: 1141 PPSQGELPGTEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGRPQATQT 1200
Query: 1201 PVPSLRGRERDRVLPSQRQPEAGPGVSLSSPINVQRIRSTSLESRECRSDPESGVSCLTT 1260
PVPSLRGRERDRVLPSQRQPEAGPGVSLSSPINVQRIRSTSLESRECRSDPESGVSCLTT
Sbjct: 1201 PVPSLRGRERDRVLPSQRQPEAGPGVSLSSPINVQRIRSTSLESRECRSDPESGVSCLTT 1260
Query: 1261 CASGGECLGAPNYRKLMRRYSISELDQGDRASLTSDVYPHPPLGMLPREAKEVEASLPIA 1320
CASGGECLGAPNYRKLMRRYSISELDQGDRASLTSDVYPHPPLGMLPREAKEVEASLPIA
Sbjct: 1261 CASGGECLGAPNYRKLMRRYSISELDQGDRASLTSDVYPHPPLGMLPREAKEVEASLPIA 1320
Query: 1321 LGPKSRSLESPTLGDPSYVQVAPETKGPRQMAVFSLPEEVYRKPAELDEDSESSKCCSIR 1380
LGPKSRSLESPTLGDPSYVQVAPETKGPRQMAVFSLPEEVYRKPAELDEDSESSKCCSIR
Sbjct: 1321 LGPKSRSLESPTLGDPSYVQVAPETKGPRQMAVFSLPEEVYRKPAELDEDSESSKCCSIR 1380
Query: 1381 YCFYYRKCDMADDASDGKDELSYSIPMKILPGMKLDEQVVPVVSRTLQVLDAATCSSSSP 1440
YCFYYRKCDMADDASDGKDELSYSIPMKILPGMKLDEQVVPVVSRTLQVLDAATCSSSSP
Sbjct: 1381 YCFYYRKCDMADDASDGKDELSYSIPMKILPGMKLDEQVVPVVSRTLQVLDAATCSSSSP 1440
Query: 1441 EASRTQEIDLRVSTFEGSLAKINALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEAR 1500
EASRTQEIDLRVSTFEGSLAKINALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEAR
Sbjct: 1441 EASRTQEIDLRVSTFEGSLAKINALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEAR 1500
Query: 1501 APKPYVSQISEYKLELALKFKELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVR 1560
APKPYVSQISEYKLELALKFKELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVR
Sbjct: 1501 APKPYVSQISEYKLELALKFKELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVR 1560
Query: 1561 LVFIVRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQ 1620
LVFIVRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQ
Sbjct: 1561 LVFIVRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQ 1620
Query: 1621 QQQQQQQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK 1662
QQQQQQQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK
Sbjct: 1621 QQQQQQQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK 1662
>gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1810
Score = 3106 bits (8053), Expect = 0.0
Identities = 1614/1777 (90%), Positives = 1629/1777 (91%), Gaps = 115/1777 (6%)
Query: 1 MQEESANDMECEQLPAEILRQVTVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAG 60
MQEESANDMECEQLPAEILRQVTVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAG
Sbjct: 34 MQEESANDMECEQLPAEILRQVTVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAG 93
Query: 61 DQIVAINEEDVSEAPRERLIELIRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVK 120
DQIVAINEEDVSEAPRERLIELIRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVK
Sbjct: 94 DQIVAINEEDVSEAPRERLIELIRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVK 153
Query: 121 VRFSEQVAVGETDAKMMKKEALLLIPNVLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRL 180
VRFSEQVAVGETDAKMMKKEALLLIPNVLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRL
Sbjct: 154 VRFSEQVAVGETDAKMMKKEALLLIPNVLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRL 213
Query: 181 SLRFIEHFALVLEYAGPEQNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVEL 240
SLRFIEHFALVLEYAGPEQNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVEL
Sbjct: 214 SLRFIEHFALVLEYAGPEQNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVEL 273
Query: 241 LRRDPAAFEYLYIQ-------------------------------XXXXXXXXIKEKNLR 269
LRRDPAAFEYLYIQ I KN+
Sbjct: 274 LRRDPAAFEYLYIQSRNDVIRERFGMDPKPEMLLGLAALHIYITVSATRPSQKISLKNVE 333
Query: 270 K----------SLSQQLK-------------AHQTHPSCGTKGSAIQAKLQYLRILNELP 306
K SL Q +K AHQTHPSCGTKGSAIQAKLQYLRILNELP
Sbjct: 334 KEWGLEPFLPPSLLQVIKEKNLRKSLSQQLKAHQTHPSCGTKGSAIQAKLQYLRILNELP 393
Query: 307 TFTGVLFNTVGLDEKQSATTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQG 366
TFTGVLFNTVGLDEKQSATTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQG
Sbjct: 394 TFTGVLFNTVGLDEKQSATTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQG 453
Query: 367 VARVETSIMDAKPLVLLMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKA 426
VARVETSIMDAKPLVLLMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKA
Sbjct: 454 VARVETSIMDAKPLVLLMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKA 513
Query: 427 DYMHSAHRPVTGGHLGKKESSYVGSVGTSPRKSSRCTPPPADSELVSFCYLHMREQRKEQ 486
DYMHSAHRPVTGGHLGKKESSYVGSVGTSPRKSSRCTPPPADSELVSFCYLHMREQRKEQ
Sbjct: 514 DYMHSAHRPVTGGHLGKKESSYVGSVGTSPRKSSRCTPPPADSELVSFCYLHMREQRKEQ 573
Query: 487 ESRTDVNENLIFFEETRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLD 546
ESRTDVNENLIFFEETRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLD
Sbjct: 574 ESRTDVNENLIFFEETRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLD 633
Query: 547 NSLGAEALNFYCDSCKAKLQSSXGPSQSGKPGSSRDNILLYDEIP--------------V 592
NSLGAEALNFYCDSCKAKLQ GP + GKPGSSRDNI+ +P
Sbjct: 634 NSLGAEALNFYCDSCKAKLQEQLGPRKGGKPGSSRDNIVDLMSLPPPGSEEEEEEEDETT 693
Query: 593 TLIDSVQTRT--VRDHAQELDD-------------------------ALVSTLQ------ 619
+L+ ++ RD++ + DD L+ ++Q
Sbjct: 694 SLLPAIAAPPPGFRDNSSDEDDPKRRAVQSQEQGRHLRGLLYDEIPVTLIDSVQTRTVRD 753
Query: 620 --------------ALEALAASEDGPHPPPPQTAGLIVLATITPESSLDSGHETNSSELT 665
ALEALAASEDGPHPPPPQTAGLIVLATITPESSLDSGHETNSSELT
Sbjct: 754 HAQELDDALVSTLQALEALAASEDGPHPPPPQTAGLIVLATITPESSLDSGHETNSSELT 813
Query: 666 DMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNP 725
DMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNP
Sbjct: 814 DMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNP 873
Query: 726 SLQPIATGQSPGPPGARRKLPQSEGQVQGERTYSLAVHPALSPQLSEQKNLSLLSPVPED 785
SLQPIATGQSPGPPGARRKLPQSEGQVQGERTYSLAVHPALSPQLSEQKNLSLLSPVPED
Sbjct: 874 SLQPIATGQSPGPPGARRKLPQSEGQVQGERTYSLAVHPALSPQLSEQKNLSLLSPVPED 933
Query: 786 KGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRLSPKLILDPKSSVTPAIISAAL 845
KGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRLSPKLILDPKSSVTPAIISAAL
Sbjct: 934 KGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRLSPKLILDPKSSVTPAIISAAL 993
Query: 846 QQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSAPETSW 905
QQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSAPETSW
Sbjct: 994 QQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSAPETSW 1053
Query: 906 NSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQATGE 965
NSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQATGE
Sbjct: 1054 NSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQATGE 1113
Query: 966 VAGKGGPVGGKPTLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQS 1025
VAGKGGPVGGKPTLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQS
Sbjct: 1114 VAGKGGPVGGKPTLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQS 1173
Query: 1026 RSHSPSCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLNGAHST 1085
RSHSPSCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLNGAHST
Sbjct: 1174 RSHSPSCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLNGAHST 1233
Query: 1086 SEGPAKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQG 1145
SEGPAKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQG
Sbjct: 1234 SEGPAKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQG 1293
Query: 1146 ELPGTEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGRPQATQTPVPSL 1205
ELPGTEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGRPQATQTPVPSL
Sbjct: 1294 ELPGTEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGRPQATQTPVPSL 1353
Query: 1206 RGRERDRVLPSQRQPEAGPGVSLSSPINVQRIRSTSLESRECRSDPESGVSCLTTCASGG 1265
RGRERDRVLPSQRQPEAGPGVSLSSPINVQRIRSTSLESRECRSDPESGVSCLTTCASGG
Sbjct: 1354 RGRERDRVLPSQRQPEAGPGVSLSSPINVQRIRSTSLESRECRSDPESGVSCLTTCASGG 1413
Query: 1266 ECLGAPNYRKLMRRYSISELDQGDRASLTSDVYPHPPLGMLPREAKEVEASLPIALGPKS 1325
ECLGAPNYRKLMRRYSISELDQGDRASLTSDVYPHPPLGMLPREAKEVEASLPIALGPKS
Sbjct: 1414 ECLGAPNYRKLMRRYSISELDQGDRASLTSDVYPHPPLGMLPREAKEVEASLPIALGPKS 1473
Query: 1326 RSLESPTLGDPSYVQVAPETKGPRQMAVFSLPEEVYRKPAELDEDSESSKCCSIRYCFYY 1385
RSLESPTLGDPSYVQVAPETKGPRQMAVFSLPEEVYRKPAELDEDSESSKCCSIRYCFYY
Sbjct: 1474 RSLESPTLGDPSYVQVAPETKGPRQMAVFSLPEEVYRKPAELDEDSESSKCCSIRYCFYY 1533
Query: 1386 RKCDMADDASDGKDELSYSIPMKILPGMKLDEQVVPVVSRTLQVLDAATCSSSSPEASRT 1445
RKCDMADDASDGKDELSYSIPMKILPGMKLDEQVVPVVSRTLQVLDAATCSSSSPEASRT
Sbjct: 1534 RKCDMADDASDGKDELSYSIPMKILPGMKLDEQVVPVVSRTLQVLDAATCSSSSPEASRT 1593
Query: 1446 QEIDLRVSTFEGSLAKINALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEARAPKPY 1505
QEIDLRVSTFEGSLAKINALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEARAPKPY
Sbjct: 1594 QEIDLRVSTFEGSLAKINALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEARAPKPY 1653
Query: 1506 VSQISEYKLELALKFKELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIV 1565
VSQISEYKLELALKFKELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIV
Sbjct: 1654 VSQISEYKLELALKFKELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIV 1713
Query: 1566 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1625
RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 1714 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1773
Query: 1626 QQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK 1662
QQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK
Sbjct: 1774 QQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK 1810
>gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1810
Score = 3106 bits (8053), Expect = 0.0
Identities = 1614/1777 (90%), Positives = 1629/1777 (91%), Gaps = 115/1777 (6%)
Query: 1 MQEESANDMECEQLPAEILRQVTVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAG 60
MQEESANDMECEQLPAEILRQVTVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAG
Sbjct: 34 MQEESANDMECEQLPAEILRQVTVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAG 93
Query: 61 DQIVAINEEDVSEAPRERLIELIRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVK 120
DQIVAINEEDVSEAPRERLIELIRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVK
Sbjct: 94 DQIVAINEEDVSEAPRERLIELIRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVK 153
Query: 121 VRFSEQVAVGETDAKMMKKEALLLIPNVLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRL 180
VRFSEQVAVGETDAKMMKKEALLLIPNVLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRL
Sbjct: 154 VRFSEQVAVGETDAKMMKKEALLLIPNVLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRL 213
Query: 181 SLRFIEHFALVLEYAGPEQNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVEL 240
SLRFIEHFALVLEYAGPEQNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVEL
Sbjct: 214 SLRFIEHFALVLEYAGPEQNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVEL 273
Query: 241 LRRDPAAFEYLYIQ-------------------------------XXXXXXXXIKEKNLR 269
LRRDPAAFEYLYIQ I KN+
Sbjct: 274 LRRDPAAFEYLYIQSRNDVIRERFGMDPKPEMLLGLAALHIYITVSATRPSQKISLKNVE 333
Query: 270 K----------SLSQQLK-------------AHQTHPSCGTKGSAIQAKLQYLRILNELP 306
K SL Q +K AHQTHPSCGTKGSAIQAKLQYLRILNELP
Sbjct: 334 KEWGLEPFLPPSLLQVIKEKNLRKSLSQQLKAHQTHPSCGTKGSAIQAKLQYLRILNELP 393
Query: 307 TFTGVLFNTVGLDEKQSATTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQG 366
TFTGVLFNTVGLDEKQSATTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQG
Sbjct: 394 TFTGVLFNTVGLDEKQSATTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQG 453
Query: 367 VARVETSIMDAKPLVLLMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKA 426
VARVETSIMDAKPLVLLMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKA
Sbjct: 454 VARVETSIMDAKPLVLLMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKA 513
Query: 427 DYMHSAHRPVTGGHLGKKESSYVGSVGTSPRKSSRCTPPPADSELVSFCYLHMREQRKEQ 486
DYMHSAHRPVTGGHLGKKESSYVGSVGTSPRKSSRCTPPPADSELVSFCYLHMREQRKEQ
Sbjct: 514 DYMHSAHRPVTGGHLGKKESSYVGSVGTSPRKSSRCTPPPADSELVSFCYLHMREQRKEQ 573
Query: 487 ESRTDVNENLIFFEETRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLD 546
ESRTDVNENLIFFEETRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLD
Sbjct: 574 ESRTDVNENLIFFEETRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLD 633
Query: 547 NSLGAEALNFYCDSCKAKLQSSXGPSQSGKPGSSRDNILLYDEIP--------------V 592
NSLGAEALNFYCDSCKAKLQ GP + GKPGSSRDNI+ +P
Sbjct: 634 NSLGAEALNFYCDSCKAKLQEQLGPRKGGKPGSSRDNIVDLMSLPPPGSEEEEEEEDETT 693
Query: 593 TLIDSVQTRT--VRDHAQELDD-------------------------ALVSTLQ------ 619
+L+ ++ RD++ + DD L+ ++Q
Sbjct: 694 SLLPAIAAPPPGFRDNSSDEDDPKRRAVQSQEQGRHLRGLLYDEIPVTLIDSVQTRTVRD 753
Query: 620 --------------ALEALAASEDGPHPPPPQTAGLIVLATITPESSLDSGHETNSSELT 665
ALEALAASEDGPHPPPPQTAGLIVLATITPESSLDSGHETNSSELT
Sbjct: 754 HAQELDDALVSTLQALEALAASEDGPHPPPPQTAGLIVLATITPESSLDSGHETNSSELT 813
Query: 666 DMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNP 725
DMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNP
Sbjct: 814 DMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNP 873
Query: 726 SLQPIATGQSPGPPGARRKLPQSEGQVQGERTYSLAVHPALSPQLSEQKNLSLLSPVPED 785
SLQPIATGQSPGPPGARRKLPQSEGQVQGERTYSLAVHPALSPQLSEQKNLSLLSPVPED
Sbjct: 874 SLQPIATGQSPGPPGARRKLPQSEGQVQGERTYSLAVHPALSPQLSEQKNLSLLSPVPED 933
Query: 786 KGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRLSPKLILDPKSSVTPAIISAAL 845
KGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRLSPKLILDPKSSVTPAIISAAL
Sbjct: 934 KGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRLSPKLILDPKSSVTPAIISAAL 993
Query: 846 QQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSAPETSW 905
QQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSAPETSW
Sbjct: 994 QQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSAPETSW 1053
Query: 906 NSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQATGE 965
NSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQATGE
Sbjct: 1054 NSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQATGE 1113
Query: 966 VAGKGGPVGGKPTLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQS 1025
VAGKGGPVGGKPTLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQS
Sbjct: 1114 VAGKGGPVGGKPTLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQS 1173
Query: 1026 RSHSPSCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLNGAHST 1085
RSHSPSCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLNGAHST
Sbjct: 1174 RSHSPSCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLNGAHST 1233
Query: 1086 SEGPAKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQG 1145
SEGPAKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQG
Sbjct: 1234 SEGPAKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQG 1293
Query: 1146 ELPGTEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGRPQATQTPVPSL 1205
ELPGTEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGRPQATQTPVPSL
Sbjct: 1294 ELPGTEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGRPQATQTPVPSL 1353
Query: 1206 RGRERDRVLPSQRQPEAGPGVSLSSPINVQRIRSTSLESRECRSDPESGVSCLTTCASGG 1265
RGRERDRVLPSQRQPEAGPGVSLSSPINVQRIRSTSLESRECRSDPESGVSCLTTCASGG
Sbjct: 1354 RGRERDRVLPSQRQPEAGPGVSLSSPINVQRIRSTSLESRECRSDPESGVSCLTTCASGG 1413
Query: 1266 ECLGAPNYRKLMRRYSISELDQGDRASLTSDVYPHPPLGMLPREAKEVEASLPIALGPKS 1325
ECLGAPNYRKLMRRYSISELDQGDRASLTSDVYPHPPLGMLPREAKEVEASLPIALGPKS
Sbjct: 1414 ECLGAPNYRKLMRRYSISELDQGDRASLTSDVYPHPPLGMLPREAKEVEASLPIALGPKS 1473
Query: 1326 RSLESPTLGDPSYVQVAPETKGPRQMAVFSLPEEVYRKPAELDEDSESSKCCSIRYCFYY 1385
RSLESPTLGDPSYVQVAPETKGPRQMAVFSLPEEVYRKPAELDEDSESSKCCSIRYCFYY
Sbjct: 1474 RSLESPTLGDPSYVQVAPETKGPRQMAVFSLPEEVYRKPAELDEDSESSKCCSIRYCFYY 1533
Query: 1386 RKCDMADDASDGKDELSYSIPMKILPGMKLDEQVVPVVSRTLQVLDAATCSSSSPEASRT 1445
RKCDMADDASDGKDELSYSIPMKILPGMKLDEQVVPVVSRTLQVLDAATCSSSSPEASRT
Sbjct: 1534 RKCDMADDASDGKDELSYSIPMKILPGMKLDEQVVPVVSRTLQVLDAATCSSSSPEASRT 1593
Query: 1446 QEIDLRVSTFEGSLAKINALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEARAPKPY 1505
QEIDLRVSTFEGSLAKINALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEARAPKPY
Sbjct: 1594 QEIDLRVSTFEGSLAKINALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEARAPKPY 1653
Query: 1506 VSQISEYKLELALKFKELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIV 1565
VSQISEYKLELALKFKELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIV
Sbjct: 1654 VSQISEYKLELALKFKELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIV 1713
Query: 1566 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1625
RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 1714 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1773
Query: 1626 QQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK 1662
QQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK
Sbjct: 1774 QQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK 1810
>gi|211971072 FERM and PDZ domain containing 4 [Homo sapiens]
Length = 1322
Score = 351 bits (901), Expect = 3e-96
Identities = 203/448 (45%), Positives = 277/448 (61%), Gaps = 55/448 (12%)
Query: 20 RQVTVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERL 79
R+V + RDP+ GFGFVAGSE+PVVVRSV PGGPSE KL+ GDQIV IN+E VS APRER+
Sbjct: 77 RKVEMRRDPVLGFGFVAGSEKPVVVRSVTPGGPSEGKLIPGDQIVMINDEPVSAAPRERV 136
Query: 80 IELIRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMMKK 139
I+L+RS KE I+LTV+ + SPKSAFISAAKKA+L+SNPVKVRFSE+V + ++ +K
Sbjct: 137 IDLVRSCKESILLTVIQPYPSPKSAFISAAKKARLKSNPVKVRFSEEVIINGQVSETVKD 196
Query: 140 EALLLIPNVLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQ 199
+LL +PNVLKV+LENGQ KSF FD T++KDV+LTLQ++LS++ IEHF+L+LE
Sbjct: 197 NSLLFMPNVLKVYLENGQTKSFRFDCSTSIKDVILTLQEKLSIKGIEHFSLMLEQRTEGA 256
Query: 200 NHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQXXXXX 259
K LLL +++ L V QR H M+CLFRISF PKDP++LLRRDP AFEYLY+Q
Sbjct: 257 GTKLLLLHEQETLTQVTQRPSSHKMRCLFRISFVPKDPIDLLRRDPVAFEYLYVQSCNDV 316
Query: 260 XXXIKEKNLRKSLSQQLKAHQTHPSCGTKGSAIQAKLQYLRILNELPTF--TGVLFNTVG 317
L+ ++ +L A Q + + T + L+Y+ L TF + VL +
Sbjct: 317 VQERFGPELKYDIALRLAALQMYIATVTTKQTQKISLKYIEKEWGLETFLPSAVLQSMKE 376
Query: 318 LDEKQSATTL------LVGPR----------HGISHVIDLK------------------- 342
+ K++ + L LV P H + + DL+
Sbjct: 377 KNIKKALSHLVKANQNLVPPGKKLSALQAKVHYLKFLSDLRLYGGRVFKATLVQAEKRSE 436
Query: 343 ------------------TNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLLM 384
TNL +L++FS +++I++F E + + RVE ++D KP+ LLM
Sbjct: 437 VTLLVGPRYGISHVINTKTNLVALLADFSHVNRIEMFSEEESLVRVELHVLDVKPITLLM 496
Query: 385 EWPEATNFACLIAGYCRLLLDSRKMVFS 412
E +A N ACL AGY RLL+DSR+ +F+
Sbjct: 497 ESSDAMNLACLTAGYYRLLVDSRRSIFN 524
Score = 87.4 bits (215), Expect = 1e-16
Identities = 58/130 (44%), Positives = 80/130 (61%), Gaps = 9/130 (6%)
Query: 559 DSCKAKLQSSXGPSQSGKPGSSRDNILLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTL 618
D ++ Q++ P K GSS N DEIPV+LID+V T + LD+A+VSTL
Sbjct: 819 DEEDSQSQAASFPEDKEK-GSSLQN----DEIPVSLIDAVPTSAEGKCEKGLDNAVVSTL 873
Query: 619 QALEALAASEDGPHPPPPQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQ 678
ALEAL+ SE+ +G+ +L +PESS DSG+ETNSSE+T+ SE+ +A KQ +
Sbjct: 874 GALEALSVSEE---QQTSDNSGVAILRAYSPESSSDSGNETNSSEMTESSELATAQKQSE 930
Query: 679 N-TTYFLAQH 687
N + FLA H
Sbjct: 931 NLSRMFLATH 940
>gi|239582741 FERM and PDZ domain containing 1 [Homo sapiens]
Length = 1578
Score = 201 bits (510), Expect = 6e-51
Identities = 140/446 (31%), Positives = 222/446 (49%), Gaps = 68/446 (15%)
Query: 32 FGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERLIELIRSAKEFIV 91
+GF P+ V +V GG + KL GDQI+ +N E + ER ++++R A++ +
Sbjct: 69 YGFHISESLPLTVVAVTAGGSAHGKLFPGDQILQMNNEPAEDLSWERAVDILREAEDSLS 128
Query: 92 LTVLH-THQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMMKKEALLLIPNVLK 150
+TV+ T PKS+F++ K+A+L++NPVKV F+E+V + + +LL +PNVLK
Sbjct: 129 ITVVRCTSGVPKSSFLTEEKRARLKTNPVKVHFAEEVLISGHS----QGNSLLCMPNVLK 184
Query: 151 VFLENGQIKSFTFDGRTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQN--HKFLLLQD 208
++LENGQ K+F F+ TTVKD++LT++++LS+R IE+FAL LE EQ + LL +
Sbjct: 185 LYLENGQTKAFKFEANTTVKDIILTVKEKLSIRSIEYFALALE----EQYSISRLHLLHE 240
Query: 209 KQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQXXXXXXXXIKEKNL 268
++ + VV+R H +CLFR+ F PKDP++LL+ DP AFEYLY+Q +
Sbjct: 241 EELIQQVVEREESHDYRCLFRVCFVPKDPLDLLKEDPVAFEYLYLQSCSDVLQERFAVEM 300
Query: 269 RKSLSQQLKAHQTHPSCGTKGSAIQAKLQYLRILNELPTFTG--VLFNTVGLDEKQSAT- 325
+ S + +L A + L+Y+ + F +L N G D K++ +
Sbjct: 301 KCSSALRLAALHIQERIYACAQPQKISLKYIEKDWGIENFISPTLLRNMKGKDIKKAISF 360
Query: 326 ------TLLVGPRHGISHVIDLKTNLTTVLSEF--------------------------- 352
LL + + L+ N +L E
Sbjct: 361 HMKRNQNLLEPRQKQLISAAQLRLNYLQILGELKTYGGRIFNATLMLQDRESYIALLVGA 420
Query: 353 ---------SKISKIQLFRENQGVARVETS------------IMDAKPLVLLMEWPEATN 391
SK++ + E ++RVE + + D K L LL+E A +
Sbjct: 421 KYGISQVINSKLNIMSTLAEFANISRVELTEESEKVSVVKVYLQDVKVLTLLLESNSAKD 480
Query: 392 FACLIAGYCRLLLDSRKMVFSRPASQ 417
ACLIAGY RLL+D +F P ++
Sbjct: 481 LACLIAGYYRLLVDPVTSIFLWPGNK 506
Score = 51.6 bits (122), Expect = 6e-06
Identities = 34/137 (24%), Positives = 58/137 (42%)
Query: 1462 INALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEARAPKPYVSQISEYKLELALKFK 1521
+ L+A P+GF+ EL +L P+ +E + L + +
Sbjct: 1408 LRQLKATPASTPEGFIQLMESLLELQDILETSWGVGNKHPPEKCTWHFTESRSRLCMGSQ 1467
Query: 1522 ELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIVRSEAQRQELLAKVEEV 1581
+L +SCR V +D+SP M A+ +FQ L L + R A+ +E + +V
Sbjct: 1468 KLLSSCRHVIRMDQSPEEMQGAVRDTFQHLVQLAGLCFQFTDCSRCSARHREAAGNLRDV 1527
Query: 1582 VRNYTFLLRAAEESTAR 1598
V Y + AA+ + R
Sbjct: 1528 VYTYHQFIEAAKSTCER 1544
>gi|4507379 TATA box binding protein [Homo sapiens]
Length = 339
Score = 64.3 bits (155), Expect = 9e-10
Identities = 33/56 (58%), Positives = 37/56 (66%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSAT 1648
++ + QQQQQQQQQQQQQQQQQQQQQQQQQQQ A AA A + T T
Sbjct: 59 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGT 114
Score = 62.8 bits (151), Expect = 3e-09
Identities = 31/44 (70%), Positives = 34/44 (77%)
Query: 1590 RAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAA 1633
R ++ + QQQQQQQQQQQQQQQQQQQQQQQQQQQ AAA
Sbjct: 57 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAA 100
Score = 62.8 bits (151), Expect = 3e-09
Identities = 31/46 (67%), Positives = 35/46 (76%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATE 1638
++ + QQQQQQQQQQQQQQQQQQQQQQQQQQQ A A AA +
Sbjct: 58 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQ 103
Score = 60.5 bits (145), Expect = 1e-08
Identities = 34/65 (52%), Positives = 38/65 (58%)
Query: 1584 NYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGS 1643
N +L + + QQQQQQQQQQQQQQQQQQQQQQQQQQQ A AA +
Sbjct: 47 NSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQST 106
Query: 1644 PTSAT 1648
AT
Sbjct: 107 SQQAT 111
Score = 59.7 bits (143), Expect = 2e-08
Identities = 32/61 (52%), Positives = 36/61 (59%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMST 1652
++ + QQQQQQQQQQQQQQQQQQQQQQQQQ AAA +T TS
Sbjct: 62 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQL 121
Query: 1653 F 1653
F
Sbjct: 122 F 122
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/77 (38%), Positives = 38/77 (49%), Gaps = 8/77 (10%)
Query: 1570 QRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQ--------Q 1621
Q L+ +EE R + ++ + QQQQQQQQQQQQQQQQQQQ Q
Sbjct: 44 QNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQ 103
Query: 1622 QQQQQQQVAAAAGAATE 1638
Q QQ +G A +
Sbjct: 104 QSTSQQATQGTSGQAPQ 120
>gi|40354197 THAP domain containing 11 [Homo sapiens]
Length = 314
Score = 63.5 bits (153), Expect = 2e-09
Identities = 39/67 (58%), Positives = 42/67 (62%), Gaps = 4/67 (5%)
Query: 1590 RAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ----VAAAAGAATEHPPGSPT 1645
R A + AR QQQQQQQQQQQQQQQQQQQQQQQQQQQ A+ A A P
Sbjct: 93 RPAGAAAARRRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSPSASTAQTAQLQPNLVSA 152
Query: 1646 SATVMST 1652
SA V+ T
Sbjct: 153 SAAVLLT 159
Score = 45.8 bits (107), Expect = 3e-04
Identities = 25/56 (44%), Positives = 31/56 (55%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSAT 1648
E AR +++QQQQQQQQQQQQQQQQQQQ + P + T+ T
Sbjct: 87 ERKVARRPAGAAAARRRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSPSASTAQT 142
Score = 41.6 bits (96), Expect = 0.006
Identities = 22/42 (52%), Positives = 25/42 (59%)
Query: 1587 FLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
F LR E +++QQQQQQQQQQQQQQQQQQ
Sbjct: 80 FPLRGVNERKVARRPAGAAAARRRQQQQQQQQQQQQQQQQQQ 121
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 62.8 bits (151), Expect = 3e-09
Identities = 34/65 (52%), Positives = 44/65 (67%), Gaps = 2/65 (3%)
Query: 1564 IVRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQ 1623
++ + Q QE K +E + + LL+ ++ + QQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 128 VMLQQQQLQEFYKKQQEQL--HLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 185
Query: 1624 QQQQQ 1628
QQQQQ
Sbjct: 186 QQQQQ 190
Score = 58.9 bits (141), Expect = 4e-08
Identities = 29/39 (74%), Positives = 30/39 (76%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1640
QQQQQQQQQQQQQQQQQQQQQQQQQQQ +HP
Sbjct: 155 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHP 193
Score = 57.4 bits (137), Expect = 1e-07
Identities = 29/41 (70%), Positives = 30/41 (73%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPG 1642
QQQQQQQQQQQQQQQQQQQQQQQQQQQ + PG
Sbjct: 154 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPG 194
Score = 52.0 bits (123), Expect = 5e-06
Identities = 33/64 (51%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Query: 1565 VRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQ 1624
V S Q Q LL + + V+ L+ + L+ Q QQQQQQQQQQQQQQQQQQQ
Sbjct: 112 VLSPQQLQALLQQQQAVMLQQQ-QLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQ 170
Query: 1625 QQQQ 1628
QQQQ
Sbjct: 171 QQQQ 174
Score = 51.2 bits (121), Expect = 8e-06
Identities = 29/52 (55%), Positives = 33/52 (63%), Gaps = 13/52 (25%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQ-------------QQQQQQQQQQVAA 1631
++ + QQQQQQQQQQQQQQQQQ QQQQQQQQQQ+AA
Sbjct: 161 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 212
Score = 45.4 bits (106), Expect = 4e-04
Identities = 22/40 (55%), Positives = 28/40 (70%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAA 1632
++ + QQQQQQQQQQ +Q ++QQQQQQQQQ AA
Sbjct: 173 QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 212
Score = 42.7 bits (99), Expect = 0.003
Identities = 24/45 (53%), Positives = 28/45 (62%), Gaps = 8/45 (17%)
Query: 1593 EESTARNLNQQQQQQQQQQQQ--------QQQQQQQQQQQQQQQV 1629
++ + QQQQQQQQQQQQ QQQQQQQQQQ QQ+
Sbjct: 171 QQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 215
Score = 35.0 bits (79), Expect = 0.61
Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 3/60 (5%)
Query: 1572 QELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQ---QQQQQQQQQQQQQ 1628
Q++ +++ V + L ++ A L QQQ Q+ ++QQ+Q Q QQQQQQQQQQ
Sbjct: 102 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 161
Score = 33.5 bits (75), Expect = 1.8
Identities = 20/32 (62%), Positives = 20/32 (62%), Gaps = 8/32 (25%)
Query: 1602 QQQQQQQQQQ--------QQQQQQQQQQQQQQ 1625
QQQQQQQQQQ QQQ Q QQ QQQQ
Sbjct: 200 QQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQ 231
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 62.8 bits (151), Expect = 3e-09
Identities = 34/65 (52%), Positives = 44/65 (67%), Gaps = 2/65 (3%)
Query: 1564 IVRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQ 1623
++ + Q QE K +E + + LL+ ++ + QQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 36 VMLQQQQLQEFYKKQQEQL--HLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 93
Query: 1624 QQQQQ 1628
QQQQQ
Sbjct: 94 QQQQQ 98
Score = 58.9 bits (141), Expect = 4e-08
Identities = 29/39 (74%), Positives = 30/39 (76%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1640
QQQQQQQQQQQQQQQQQQQQQQQQQQQ +HP
Sbjct: 63 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHP 101
Score = 57.4 bits (137), Expect = 1e-07
Identities = 29/41 (70%), Positives = 30/41 (73%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPG 1642
QQQQQQQQQQQQQQQQQQQQQQQQQQQ + PG
Sbjct: 62 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPG 102
Score = 52.0 bits (123), Expect = 5e-06
Identities = 33/64 (51%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Query: 1565 VRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQ 1624
V S Q Q LL + + V+ L+ + L+ Q QQQQQQQQQQQQQQQQQQQ
Sbjct: 20 VLSPQQLQALLQQQQAVMLQQQ-QLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQ 78
Query: 1625 QQQQ 1628
QQQQ
Sbjct: 79 QQQQ 82
Score = 51.2 bits (121), Expect = 8e-06
Identities = 29/52 (55%), Positives = 33/52 (63%), Gaps = 13/52 (25%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQ-------------QQQQQQQQQQVAA 1631
++ + QQQQQQQQQQQQQQQQQ QQQQQQQQQQ+AA
Sbjct: 69 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 120
Score = 45.4 bits (106), Expect = 4e-04
Identities = 22/40 (55%), Positives = 28/40 (70%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAA 1632
++ + QQQQQQQQQQ +Q ++QQQQQQQQQ AA
Sbjct: 81 QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 120
Score = 42.7 bits (99), Expect = 0.003
Identities = 24/45 (53%), Positives = 28/45 (62%), Gaps = 8/45 (17%)
Query: 1593 EESTARNLNQQQQQQQQQQQQ--------QQQQQQQQQQQQQQQV 1629
++ + QQQQQQQQQQQQ QQQQQQQQQQ QQ+
Sbjct: 79 QQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 123
Score = 35.0 bits (79), Expect = 0.61
Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 3/60 (5%)
Query: 1572 QELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQ---QQQQQQQQQQQQQ 1628
Q++ +++ V + L ++ A L QQQ Q+ ++QQ+Q Q QQQQQQQQQQ
Sbjct: 10 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 69
Score = 33.5 bits (75), Expect = 1.8
Identities = 20/32 (62%), Positives = 20/32 (62%), Gaps = 8/32 (25%)
Query: 1602 QQQQQQQQQQ--------QQQQQQQQQQQQQQ 1625
QQQQQQQQQQ QQQ Q QQ QQQQ
Sbjct: 108 QQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQ 139
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 62.8 bits (151), Expect = 3e-09
Identities = 34/65 (52%), Positives = 44/65 (67%), Gaps = 2/65 (3%)
Query: 1564 IVRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQ 1623
++ + Q QE K +E + + LL+ ++ + QQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 153 VMLQQQQLQEFYKKQQEQL--HLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 210
Query: 1624 QQQQQ 1628
QQQQQ
Sbjct: 211 QQQQQ 215
Score = 58.9 bits (141), Expect = 4e-08
Identities = 29/39 (74%), Positives = 30/39 (76%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1640
QQQQQQQQQQQQQQQQQQQQQQQQQQQ +HP
Sbjct: 180 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHP 218
Score = 57.4 bits (137), Expect = 1e-07
Identities = 29/41 (70%), Positives = 30/41 (73%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPG 1642
QQQQQQQQQQQQQQQQQQQQQQQQQQQ + PG
Sbjct: 179 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPG 219
Score = 52.0 bits (123), Expect = 5e-06
Identities = 33/64 (51%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Query: 1565 VRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQ 1624
V S Q Q LL + + V+ L+ + L+ Q QQQQQQQQQQQQQQQQQQQ
Sbjct: 137 VLSPQQLQALLQQQQAVMLQQQ-QLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQ 195
Query: 1625 QQQQ 1628
QQQQ
Sbjct: 196 QQQQ 199
Score = 51.2 bits (121), Expect = 8e-06
Identities = 29/52 (55%), Positives = 33/52 (63%), Gaps = 13/52 (25%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQ-------------QQQQQQQQQQVAA 1631
++ + QQQQQQQQQQQQQQQQQ QQQQQQQQQQ+AA
Sbjct: 186 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 237
Score = 45.4 bits (106), Expect = 4e-04
Identities = 22/40 (55%), Positives = 28/40 (70%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAA 1632
++ + QQQQQQQQQQ +Q ++QQQQQQQQQ AA
Sbjct: 198 QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 237
Score = 42.7 bits (99), Expect = 0.003
Identities = 24/45 (53%), Positives = 28/45 (62%), Gaps = 8/45 (17%)
Query: 1593 EESTARNLNQQQQQQQQQQQQ--------QQQQQQQQQQQQQQQV 1629
++ + QQQQQQQQQQQQ QQQQQQQQQQ QQ+
Sbjct: 196 QQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 240
Score = 35.0 bits (79), Expect = 0.61
Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 3/60 (5%)
Query: 1572 QELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQ---QQQQQQQQQQQQQ 1628
Q++ +++ V + L ++ A L QQQ Q+ ++QQ+Q Q QQQQQQQQQQ
Sbjct: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
Score = 33.5 bits (75), Expect = 1.8
Identities = 20/32 (62%), Positives = 20/32 (62%), Gaps = 8/32 (25%)
Query: 1602 QQQQQQQQQQ--------QQQQQQQQQQQQQQ 1625
QQQQQQQQQQ QQQ Q QQ QQQQ
Sbjct: 225 QQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQ 256
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 61.6 bits (148), Expect = 6e-09
Identities = 32/79 (40%), Positives = 44/79 (55%)
Query: 1566 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1625
+ + Q+Q+ + ++ + + + ++ R QQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 2057 QQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQH 2116
Query: 1626 QQQVAAAAGAATEHPPGSP 1644
QQQ A P P
Sbjct: 2117 QQQQQQQAAPPQPQPQSQP 2135
Score = 60.5 bits (145), Expect = 1e-08
Identities = 32/78 (41%), Positives = 45/78 (57%)
Query: 1566 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1625
+ + Q+Q+ + ++ + + +R ++ QQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 2056 QQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQ 2115
Query: 1626 QQQVAAAAGAATEHPPGS 1643
QQ A + P S
Sbjct: 2116 HQQQQQQQAAPPQPQPQS 2133
Score = 57.8 bits (138), Expect = 9e-08
Identities = 30/39 (76%), Positives = 32/39 (82%)
Query: 1589 LRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQ 1627
++A STA QQQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 2038 VQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQ 2076
Score = 53.5 bits (127), Expect = 2e-06
Identities = 25/28 (89%), Positives = 26/28 (92%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQV 1629
QQQQQQQQQQQQQQQQQQQQQQQQQ +
Sbjct: 2052 QQQQQQQQQQQQQQQQQQQQQQQQQYHI 2079
Score = 51.2 bits (121), Expect = 8e-06
Identities = 31/64 (48%), Positives = 36/64 (56%), Gaps = 13/64 (20%)
Query: 1578 VEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQ-------------QQQQQQQQ 1624
V+ VR+ L ++ + QQQQQQQQQQQQQQQ QQQQQQQQ
Sbjct: 2038 VQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQ 2097
Query: 1625 QQQQ 1628
QQQQ
Sbjct: 2098 QQQQ 2101
Score = 49.3 bits (116), Expect = 3e-05
Identities = 23/37 (62%), Positives = 28/37 (75%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQV 1629
++ + QQQQQQQQQQQQQQQQQ +QQQQQQ+
Sbjct: 2051 QQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQI 2087
Score = 48.1 bits (113), Expect = 7e-05
Identities = 30/67 (44%), Positives = 34/67 (50%), Gaps = 22/67 (32%)
Query: 1588 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQ----------------------Q 1625
+LR ++ + QQQQQQQQQQQQQQQ QQQQQQQ Q
Sbjct: 2087 ILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQ 2146
Query: 1626 QQQVAAA 1632
QQQ AA
Sbjct: 2147 QQQQTAA 2153
Score = 40.0 bits (92), Expect = 0.019
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 19/78 (24%)
Query: 1568 EAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQ------------ 1615
+ Q+Q++L + ++ + + ++ + QQQQQQ QQQQQQQ
Sbjct: 2081 QQQQQQILRQQQQQQQQ-----QQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQP 2135
Query: 1616 --QQQQQQQQQQQQQVAA 1631
Q+Q QQ QQQQQ AA
Sbjct: 2136 QFQRQGLQQTQQQQQTAA 2153
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 60.8 bits (146), Expect = 1e-08
Identities = 32/52 (61%), Positives = 36/52 (69%)
Query: 1596 TARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSA 1647
T + QQQQQQQQQQQQQQQQQQQQQQQQQQQ ++ A + S SA
Sbjct: 587 TQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISA 638
Score = 59.3 bits (142), Expect = 3e-08
Identities = 29/49 (59%), Positives = 35/49 (71%)
Query: 1583 RNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAA 1631
+N LL ++ + QQQQQQQQQQQQQQQQQQQQQQQQQ ++A
Sbjct: 578 QNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISA 626
Score = 58.2 bits (139), Expect = 7e-08
Identities = 28/63 (44%), Positives = 43/63 (68%)
Query: 1566 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1625
+ + Q+Q+ + ++ + + + ++ +++ QQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 602 QQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQ 661
Query: 1626 QQQ 1628
QQQ
Sbjct: 662 QQQ 664
Score = 58.2 bits (139), Expect = 7e-08
Identities = 30/75 (40%), Positives = 47/75 (62%)
Query: 1566 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1625
+ + Q+Q+ + ++ ++ + ++ ++ + QQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 604 QQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQ 663
Query: 1626 QQQVAAAAGAATEHP 1640
QQ + A + P
Sbjct: 664 QQPSSQPAQSLPSQP 678
Score = 57.4 bits (137), Expect = 1e-07
Identities = 30/76 (39%), Positives = 46/76 (60%)
Query: 1566 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1625
+ + Q+Q+ + ++ + + + ++ + QQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 603 QQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQ 662
Query: 1626 QQQVAAAAGAATEHPP 1641
QQQ ++ + P
Sbjct: 663 QQQPSSQPAQSLPSQP 678
Score = 57.0 bits (136), Expect = 1e-07
Identities = 28/41 (68%), Positives = 33/41 (80%)
Query: 1588 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
+L + + + + QQQQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 574 VLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQ 614
Score = 55.8 bits (133), Expect = 3e-07
Identities = 30/75 (40%), Positives = 45/75 (60%)
Query: 1566 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1625
+ + Q+Q+ + ++ + + A ++ ++ QQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 601 QQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQ 660
Query: 1626 QQQVAAAAGAATEHP 1640
QQQ ++ A P
Sbjct: 661 QQQQQPSSQPAQSLP 675
Score = 54.3 bits (129), Expect = 1e-06
Identities = 30/54 (55%), Positives = 34/54 (62%), Gaps = 5/54 (9%)
Query: 1596 TARNLNQQQ-----QQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSP 1644
+A+ QQQ QQQQQQQQQQQQQQQQQQQQQQQQ + + P P
Sbjct: 625 SAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQP 678
Score = 52.8 bits (125), Expect = 3e-06
Identities = 31/75 (41%), Positives = 43/75 (57%), Gaps = 5/75 (6%)
Query: 1593 EESTARNLNQQQQQQ-----QQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSA 1647
++ ++ + QQQQQQ QQQQQQQQQQQQQQQQQQQQQ +++ P+
Sbjct: 619 QQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQP 678
Query: 1648 TVMSTFTHSLKTLIK 1662
+ S K L++
Sbjct: 679 LLRSPLPLQQKLLLQ 693
Score = 52.4 bits (124), Expect = 4e-06
Identities = 29/54 (53%), Positives = 36/54 (66%), Gaps = 4/54 (7%)
Query: 1584 NYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQ----QQQQQQQVAAAA 1633
+YT + ++ + QQQQQQQQQQQQQQQQQQQ QQQQQQQ + +A
Sbjct: 585 HYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISA 638
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/76 (39%), Positives = 37/76 (48%), Gaps = 17/76 (22%)
Query: 1593 EESTARNLNQQQQQQQQQQQQ-----------------QQQQQQQQQQQQQQQVAAAAGA 1635
++ + QQQQQQQQQQQQ QQQQQQQQQQQQQQQ
Sbjct: 601 QQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQ 660
Query: 1636 ATEHPPGSPTSATVMS 1651
+ P S + ++ S
Sbjct: 661 QQQQQPSSQPAQSLPS 676
Score = 36.2 bits (82), Expect = 0.27
Identities = 75/388 (19%), Positives = 147/388 (37%), Gaps = 34/388 (8%)
Query: 808 EEQVSELRDNLPKEV-----RLSPKLILDPKSSVTPAIISAALQQVVHNKSLVTAGGALG 862
+ Q S R +LP E SP L P S SA + N +L T+
Sbjct: 347 QSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPS 406
Query: 863 NPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAP 922
P S+ + + + R S S ++ LK +I+ + + + QHQ + ++ P
Sbjct: 407 VPQSQAQPQTGSGASRALPSWQEVSHAQQLK-QIAANRQQHARMQQHQQQHQPTNWSALP 465
Query: 923 TGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQATGEVAGKGGPVGGKPTLQKQ 982
+ + Q++ +P +F +++ ++S G G G + K
Sbjct: 466 SSAGPSPGPFGQEK--IPSPSFGQQTFSPQSS------PMPGVAGGSGQSKVMANYMYKA 517
Query: 983 GTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSPSCQPHGHSPSSQ 1042
G S+QG + K L + + +P + +P H S Q
Sbjct: 518 GP-SAQGGHLDVLMQQKPQDLSRSFI----------NNPHPAMEPRQGNTKPLFHFNSDQ 566
Query: 1043 SRGQSPSCQPRGQSP----LRSQAASRQVSTMPSRKLETTLNGAHSTSEGPAKPKSSRGP 1098
+ Q PS P P Q +Q ++ + + + +SS
Sbjct: 567 ANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISA 626
Query: 1099 FRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQGELPGTEYLQPPAP 1158
+ + S+ +Q+++ ++Q Q Q+ +Q + + ++ P+Q LP L+ P P
Sbjct: 627 QQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQS-LPSQPLLRSPLP 685
Query: 1159 GRCSC---QLRSSPVQ-QGPGMSREQRR 1182
+ Q+++ P+ G +S++QR+
Sbjct: 686 LQQKLLLQQMQNQPIAGMGYQVSQQQRQ 713
>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
Length = 1420
Score = 60.5 bits (145), Expect = 1e-08
Identities = 39/89 (43%), Positives = 50/89 (56%), Gaps = 7/89 (7%)
Query: 1564 IVRSEAQRQELLAKVEEVVRNYTFLL--RAAEESTARNLNQQQQQQQQQQQQQQQQQQQQ 1621
++R Q Q+ + V + LL ++ A + QQQQQQQQQQQQQQQQQQQQ
Sbjct: 1205 VMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQ 1264
Query: 1622 QQQQQQQVAAAAGAATEHPPGSPTSATVM 1650
QQQQQQQ A PP + T++ M
Sbjct: 1265 QQQQQQQQTQAFS-----PPPNVTASPSM 1288
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 60.1 bits (144), Expect = 2e-08
Identities = 33/58 (56%), Positives = 39/58 (67%), Gaps = 5/58 (8%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVM 1650
++ A + QQQQQQQQQQQQQQQQQQQQQQQQQQQ A PP + T++ M
Sbjct: 1240 QQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFS-----PPPNVTASPSM 1292
Score = 51.6 bits (122), Expect = 6e-06
Identities = 28/55 (50%), Positives = 35/55 (63%)
Query: 1572 QELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQ 1626
Q + + E++ ++ R A + QQQQQQQQQQQQQQQQQQQQQQQ Q
Sbjct: 1224 QMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQ 1278
Score = 47.4 bits (111), Expect = 1e-04
Identities = 23/45 (51%), Positives = 29/45 (64%)
Query: 1584 NYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
N + + + E + + QQ+ QQQQQQQQQQQQQQQQQQQ
Sbjct: 1222 NAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQ 1266
Score = 42.4 bits (98), Expect = 0.004
Identities = 21/45 (46%), Positives = 27/45 (60%)
Query: 1588 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAA 1632
++ ++ + QQQQQQQQQQQQQQQQQQ Q V A+
Sbjct: 1245 MMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTAS 1289
Score = 41.6 bits (96), Expect = 0.006
Identities = 22/52 (42%), Positives = 29/52 (55%)
Query: 1569 AQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQ 1620
AQR L + +++ ++ + QQQQQQQQQQQQQQQQQ Q
Sbjct: 1227 AQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQ 1278
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 59.7 bits (143), Expect = 2e-08
Identities = 30/36 (83%), Positives = 32/36 (88%)
Query: 1598 RNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAA 1633
++L QQQQQQQQQQQQQQQQQQQQQQQQQQQ AA
Sbjct: 520 QSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAA 555
Score = 57.4 bits (137), Expect = 1e-07
Identities = 30/44 (68%), Positives = 33/44 (75%)
Query: 1588 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAA 1631
L A + + QQQQQQQQQQQQQQQQQQQQQQQQQ+Q AA
Sbjct: 512 LQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAA 555
Score = 53.5 bits (127), Expect = 2e-06
Identities = 27/33 (81%), Positives = 27/33 (81%)
Query: 1604 QQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQQQQQ AA
Sbjct: 523 QQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAA 555
Score = 42.0 bits (97), Expect = 0.005
Identities = 20/39 (51%), Positives = 27/39 (69%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAA 1631
++ + QQQQQQQQQQQQQQQQQ+Q +Q+A+
Sbjct: 525 QQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMAS 563
Score = 33.9 bits (76), Expect = 1.4
Identities = 18/32 (56%), Positives = 20/32 (62%)
Query: 1590 RAAEESTARNLNQQQQQQQQQQQQQQQQQQQQ 1621
RAA ++ Q QQQ QQQQQ QQQQQQ
Sbjct: 278 RAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQ 309
Score = 33.9 bits (76), Expect = 1.4
Identities = 16/25 (64%), Positives = 18/25 (72%)
Query: 1600 LNQQQQQQQQQQQQQQQQQQQQQQQ 1624
L++ Q QQQ QQQQQ QQQQQQ
Sbjct: 285 LSKMHAQPPQQQPQQQQQPQQQQQQ 309
Score = 33.5 bits (75), Expect = 1.8
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 3/51 (5%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQ---QQQQQQQQQQQVAAAAGAATEHP 1640
++ + QQQQQQQQQQQ+Q +Q + QQQ++ A HP
Sbjct: 531 QQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHP 581
Score = 32.7 bits (73), Expect = 3.0
Identities = 18/36 (50%), Positives = 19/36 (52%)
Query: 1607 QQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPG 1642
Q QQQ QQQQQ QQQQQQ A + P G
Sbjct: 291 QPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVG 326
>gi|189491748 ataxin 1 [Homo sapiens]
Length = 815
Score = 59.3 bits (142), Expect = 3e-08
Identities = 34/57 (59%), Positives = 38/57 (66%), Gaps = 6/57 (10%)
Query: 1594 ESTARNLNQQQQQQQQQQQQ---QQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSA 1647
++ QQQQQQQQQQQQ QQQQQQQQQQQQQQ ++ A G T PGSP A
Sbjct: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLIT---PGSPPPA 242
>gi|51479158 ataxin 1 [Homo sapiens]
Length = 815
Score = 59.3 bits (142), Expect = 3e-08
Identities = 34/57 (59%), Positives = 38/57 (66%), Gaps = 6/57 (10%)
Query: 1594 ESTARNLNQQQQQQQQQQQQ---QQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSA 1647
++ QQQQQQQQQQQQ QQQQQQQQQQQQQQ ++ A G T PGSP A
Sbjct: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLIT---PGSPPPA 242
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 59.3 bits (142), Expect = 3e-08
Identities = 173/749 (23%), Positives = 261/749 (34%), Gaps = 137/749 (18%)
Query: 650 ESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQ 709
+S+ SGH +SSEL+ + + M +Q+ ++ L A P R +S +A
Sbjct: 1374 QSTRSSGH--SSSELSPDAVEKAGMSSNQS--------ISSPVLDAVPRTPSRERSSSAS 1423
Query: 710 A------VLTAPYSLGRPDPNPSLQPIA--------TGQSPGPPGARRKLPQSEGQVQGE 755
+ + P R +P L+ + +G SPG + +P++ + + E
Sbjct: 1424 SPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPG----MKDIPRTPSRGRSE 1479
Query: 756 RTYSLAVHPALSPQLSEQKNLSLLSPVPEDK--GPGHTRAGLEMSLRAATSSLSEEQVSE 813
S P PQ ++ S SP +K P R+G E S+ +Q +
Sbjct: 1480 CDSS--PEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSV---------DQKTV 1528
Query: 814 LRDNLPKEVRLSPKLILDPKSSVTPAIISAALQQVVHNKSLVTAGGALGNPPSRGERRLE 873
R L + R LD K S +P Q+ + S + P + R
Sbjct: 1529 ARTPLGQRSRSGSSQELDVKPSASP-------QERSESDSSPDSKAKTRTPLRQRSR--- 1578
Query: 874 ASMGRPEVSMMSSSASKNLKFKISPSAPETSWNSQH-QLGAEVSSSPRAP---------- 922
S PEV S + + + SP + + Q G++ S P+AP
Sbjct: 1579 -SGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSR 1637
Query: 923 TGS----RADSLHLSQQEDSLPVQNFPPKSYLLRT-SRESVGKQATGEVAGKGGPVGGKP 977
+GS R S S +S P PPKS R SR S + + P
Sbjct: 1638 SGSSSKGRGPSPEGSSSTESSP--EHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSP 1695
Query: 978 TLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSPSCQPHGH 1037
L ++ +S + A S RS+ PR ++ SP +S S +
Sbjct: 1696 ELTRKARLSRRSRSAS-SSPETRSRTP-----PRHRRSPSVSSPEPAEKSRSSRRRRSAS 1749
Query: 1038 SPSSQS---RGQSPSCQPRGQSPLRSQAAS---------------------RQVSTMPSR 1073
SP +++ RG+SPS +PRG RS++ RQ S SR
Sbjct: 1750 SPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSR 1809
Query: 1074 KLETTLNGAHSTSEGPAKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELE 1133
G+ S PA+ +SSR R R S T PT +K+ K +
Sbjct: 1810 VTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRAS 1869
Query: 1134 FLEELLKPPSQGELPGT---EYLQPPAPGRCSCQLRSSPVQQGPGMSR--------EQRR 1182
P T + P R + R+SPV + SR R
Sbjct: 1870 --------------PATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRA 1915
Query: 1183 SCDCKRICRGGRPQAT----QTPVPSLRGRERDRVLPSQRQPEAGPGVSLSSPINVQRIR 1238
S +R R P T ++ P+ R R R R P R+ S S V R R
Sbjct: 1916 SPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRR------SRSRTPPVTRRR 1969
Query: 1239 STSLESRECRSDPESGVSCLTTCASGGECLGAPNYRKLMRRYSISELDQGDRASLTSDVY 1298
S S S R S S +T S R R ++ R
Sbjct: 1970 SRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRR 2029
Query: 1299 PHPPLGMLPREAKEVEASLPIALGPKSRS 1327
+LPR K + P+A+ +SRS
Sbjct: 2030 SRSRTPLLPR--KRSRSRSPLAIRRRSRS 2056
Score = 53.9 bits (128), Expect = 1e-06
Identities = 93/405 (22%), Positives = 158/405 (39%), Gaps = 43/405 (10%)
Query: 863 NPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAP 922
NPPS + S + + SS+S++ SP +P+ + S+H + S P
Sbjct: 392 NPPSEASPTRDRSPPKSPEKLPQSSSSES-----SPPSPQPTKVSRHASSSPESPKPAPA 446
Query: 923 TGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQATGEVAGKGGPVGGKPTLQKQ 982
GS + ++ + KS+ SR +G+ + A +G PT +
Sbjct: 447 PGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRR-MGRSRSPATAKRGRSRSRTPTKRGH 505
Query: 983 GTISS----QGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSPSCQ---PH 1035
S + AQ + + S P+ P +S + Q R S S + H
Sbjct: 506 SRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQR--PGWSRSRNTQRRGRSRSARRGRSH 563
Query: 1036 GHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLNGAHSTSEGPAK--PK 1093
SP+++ R +S + RG+S R+ A R S P+R+ S S PA+
Sbjct: 564 SRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRR--------RSRSRTPARRGRS 615
Query: 1094 SSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQGELPGTEYL 1153
SR P R R+ + R + + R++ + + P +G
Sbjct: 616 RSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGR------S 669
Query: 1154 QPPAPGRCSCQLRS-SPVQQGPGMSREQRRSCDCKR-ICRGGRPQATQTPVPSLRGR--- 1208
+ P R S + RS +P ++G SR RR R + R GR + + P RGR
Sbjct: 670 RSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGR---SHSRTPQRRGRSGS 726
Query: 1209 ---ERDRVLPSQRQPEAGPGVSL-SSPINVQRIRSTSLESRECRS 1249
+++ SQR+ + + S I+ +R RS S + +S
Sbjct: 727 SSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKS 771
Score = 52.0 bits (123), Expect = 5e-06
Identities = 98/407 (24%), Positives = 151/407 (37%), Gaps = 57/407 (14%)
Query: 866 SRGERRLEASMGRPEV--SMMSSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAPT 923
SR +R S PE+ S +SS S++L S+P + S+ L +S S P
Sbjct: 734 SRTSQRRSRSNSSPEMKKSRISSRRSRSL------SSPRSKAKSRLSLRRSLSGSSPCPK 787
Query: 924 GSRADSLHLSQQEDSLPVQNF-------------PPKSYLLRTSRESVGKQATGEVAGKG 970
S+ S P PPK SR+S + G
Sbjct: 788 QKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSG 847
Query: 971 GPVGGKPTLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSP 1030
P +QG+I+S Q TP+R E+S P + ++PS S S S
Sbjct: 848 TP-------PRQGSITSPQANEQ-SVTPQRRSCFESSPDPE----LKSRTPSRHSCSGSS 895
Query: 1031 SCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPS-RKLETTLNGAHSTSEGP 1089
+ +P QS +S S QP+ ++ + + S S+ PS ++ + S S P
Sbjct: 896 PPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSP 955
Query: 1090 AKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQGELPG 1149
SR R + S++ T+ K ET RQ+ + Y + PP P
Sbjct: 956 CSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYP---KVKAQTPPG----PS 1008
Query: 1150 TEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGRPQATQTPVPSLRGRE 1209
+ P P S + S VQ PG C + P + V SL+ +
Sbjct: 1009 LSGSKSPCPQEKS---KDSLVQSCPGSLSL------CAGVKSSTPPGESYFGVSSLQLKG 1059
Query: 1210 RDRVLPSQRQPEAGPGVSLSSPINVQRIRSTSLESRECRSDPESGVS 1256
+ + P R + P V S S SL+S+ ++ P+ G S
Sbjct: 1060 QSQTSPDHRSDTSSPEVRQS------HSESPSLQSKS-QTSPKGGRS 1099
Score = 39.3 bits (90), Expect = 0.032
Identities = 79/326 (24%), Positives = 114/326 (34%), Gaps = 77/326 (23%)
Query: 1024 QSRSHSPSCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASR----------QVSTMPSR 1073
+SRS S + HS + Q RG+S S R SQ SR ++S+ SR
Sbjct: 701 RSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSR 760
Query: 1074 KLETTLNGAHS-------------------------TSEGPAKPKS-SRGPFRLRNLFSA 1107
L + + A S + G ++PK+ SR P R R+ S+
Sbjct: 761 SLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR-RSRSSS 819
Query: 1108 TFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQGELPGTE-YLQPPAPGRCSCQLR 1166
+ P +QK +T RQ+ ++ + PP QG + + Q P R SC
Sbjct: 820 SPPPKQKSKTPSRQSHSSSSPHPKV----KSGTPPRQGSITSPQANEQSVTPQRRSC-FE 874
Query: 1167 SSPVQQGPGMSREQRRSCDCKRICRGGRPQATQTPVPSLRGRERDRVLPSQRQPEAGPGV 1226
SSP E + + C G P ++ P P P
Sbjct: 875 SSP-------DPELKSRTPSRHSCSGSSPPRVKSSTP----------------PRQSPSR 911
Query: 1227 SLSSPINVQRIRSTSLESRECRSDPE-SGVSCLTTCASGGECLGAPNYR-KLMRRYSISE 1284
S S V+ I S S S P S V+ TT N +L+ RYS S
Sbjct: 912 SSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSG 971
Query: 1285 LDQGD---------RASLTSDVYPHP 1301
D R S + + P+P
Sbjct: 972 SSSPDTKVKPETPPRQSHSGSISPYP 997
Score = 38.9 bits (89), Expect = 0.042
Identities = 95/420 (22%), Positives = 153/420 (36%), Gaps = 51/420 (12%)
Query: 713 TAPYSLGRPDPNPSLQPIATGQSPGPPGARRKLPQSEGQVQGERTYSLAVHPA------L 766
T P + P + + Q A+ GP A P + + G RT + A+ PA +
Sbjct: 2316 TPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVN---IAGSRT-AAALAPASLTSARM 2371
Query: 767 SPQLSEQKNLSLLSPVPE-DKGPGHTRAGLEMSLRAAT--SSLSEEQVSELRDNLPKE-- 821
+P LS S P+ ++ G T L R+ T S+ S+ +++ R P
Sbjct: 2372 APALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRM 2431
Query: 822 -----VRLSPKLILDPKSSVTPAI------ISAALQQVVHNKSLVTAGGALGNPPSRGER 870
L P P+S V A + A V ++SL ++G S G+
Sbjct: 2432 GQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSL-SSGAVATTTSSAGDH 2490
Query: 871 RLEASMGRP--------EVSMMSSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAP 922
S+ P E + + + + P+ S +S + SSS +
Sbjct: 2491 NGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSS 2550
Query: 923 TGSRADSLHLSQQE-DSLPVQNFPPKSYLLRTSRESVGKQATGEVAGKGGPVGGKPTLQK 981
+ S + S E SLPVQ P+ L R + A E +G P +PT K
Sbjct: 2551 SSSSSSGSSSSDSEGSSLPVQ---PEVALKRVPSPT---PAPKEAVREGRPP--EPTPAK 2602
Query: 982 QGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSPS-----CQPHG 1036
+ SS + S+ S +S ++ + S S S S SP+ P
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662
Query: 1037 HSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLNGAHSTSEGPAKPKSSR 1096
SP G+ S PR P+ S SR +S P + + + + + + SR
Sbjct: 2663 ASPKKPPPGERRSRSPR--KPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSR 2720
Score = 36.6 bits (83), Expect = 0.21
Identities = 116/529 (21%), Positives = 191/529 (36%), Gaps = 87/529 (16%)
Query: 632 HPPPPQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKD 691
H PQ G ++ S S + S+ +M + S + ++ + + K
Sbjct: 714 HSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKK--SRISSRRSRSLSSPRSKAKS 771
Query: 692 SLLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNPSLQPIATGQSPG---------PPGAR 742
L R+ L C Q T P R + S QP A ++P PP +
Sbjct: 772 RLSLRRSLSGS-SPCPKQKSQTPP----RRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQK 826
Query: 743 RKLPQSEGQVQGERTYSLAVHPAL------------SPQLSEQ------KNLSLLSPVPE 784
K P + S + HP + SPQ +EQ ++ SP PE
Sbjct: 827 SKTPSRQSHS------SSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPE 880
Query: 785 DKGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRLSPKLILDPKSSVTPAIISAA 844
K +R S S + + S R + P+ K I+ P+ S +
Sbjct: 881 LKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQP---KVKAIISPRQRSHSGSSSPS 937
Query: 845 LQQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSAPETS 904
+V + + +P S E RL + S S S + K+ P P
Sbjct: 938 PSRVTSRTTPRRSRSV--SPCSNVESRL--------LPRYSHSGSSSPDTKVKPETPPRQ 987
Query: 905 WNSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQATG 964
+S +S P+ + LS + P + S++S+ + G
Sbjct: 988 SHS-----GSISPYPKVKAQTPPGP-SLSGSKSPCPQEK----------SKDSLVQSCPG 1031
Query: 965 EVAGKGGPVGGKPTLQKQGTISSQGEKAQLESTPK-RSKLEETSLVPRATYPMALQSPSC 1023
++ G P + +SS K Q +++P RS + + +LQS S
Sbjct: 1032 SLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQ 1091
Query: 1024 ------QSRSHSPSCQPHGHSPSSQSRGQ---SPSCQPRGQSPLRS--QAASRQVSTMPS 1072
+SRS SP + SP Q RG+ SP + G SP +S Q+ S T+ S
Sbjct: 1092 TSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLK-SGMSPEQSRFQSDSSSYPTVDS 1150
Query: 1073 RKL--ETTLNGAHSTSEG--PAKPKSSRGPFRLRNLFSATFPTRQKKET 1117
L ++ L A S + P + ++ P R ++ FS FP + + E+
Sbjct: 1151 NSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFS-PFPVQDRPES 1198
>gi|226442791 runt-related transcription factor 2 isoform b [Homo
sapiens]
Length = 499
Score = 58.9 bits (141), Expect = 4e-08
Identities = 29/32 (90%), Positives = 30/32 (93%)
Query: 1605 QQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAA 80
Score = 58.5 bits (140), Expect = 5e-08
Identities = 29/33 (87%), Positives = 30/33 (90%)
Query: 1604 QQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAA 81
Score = 58.2 bits (139), Expect = 7e-08
Identities = 29/34 (85%), Positives = 30/34 (88%)
Query: 1603 QQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAA 82
Score = 57.8 bits (138), Expect = 9e-08
Identities = 29/35 (82%), Positives = 30/35 (85%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAA 83
Score = 56.2 bits (134), Expect = 3e-07
Identities = 30/56 (53%), Positives = 36/56 (64%)
Query: 1607 QQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK 1662
QQQQQQQQQQQQQQQQQQQQQQ AAA AA + +A H +T+++
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVE 104
Score = 55.5 bits (132), Expect = 4e-07
Identities = 28/35 (80%), Positives = 29/35 (82%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 50 QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAA 84
Score = 53.1 bits (126), Expect = 2e-06
Identities = 27/35 (77%), Positives = 28/35 (80%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 51 QQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAA 85
Score = 52.0 bits (123), Expect = 5e-06
Identities = 28/45 (62%), Positives = 29/45 (64%)
Query: 1597 ARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPP 1641
A QQQQQQQQQQQQQQQQQQQQ+ AAAA AA P
Sbjct: 47 AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVP 91
Score = 40.4 bits (93), Expect = 0.014
Identities = 22/50 (44%), Positives = 25/50 (50%)
Query: 1592 AEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPP 1641
A + + QQQQQQQQQQQQQQQ+ AAAA PP
Sbjct: 47 AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPP 96
Score = 38.5 bits (88), Expect = 0.055
Identities = 22/61 (36%), Positives = 30/61 (49%)
Query: 1591 AAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVM 1650
AA++ + QQQQQQQQQQQQQQ+ AAAA P + T ++
Sbjct: 47 AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEII 106
Query: 1651 S 1651
+
Sbjct: 107 A 107
Score = 33.5 bits (75), Expect = 1.8
Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 6/53 (11%)
Query: 1588 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1640
++ A ++ + QQQQQQ QQQQQQQ+ AAAA AA P
Sbjct: 45 VVAAQQQQQQQQQQQQQQQQ------QQQQQQQEAAAAAAAAAAAAAAAAAVP 91
>gi|226442783 runt-related transcription factor 2 isoform a [Homo
sapiens]
Length = 521
Score = 58.9 bits (141), Expect = 4e-08
Identities = 29/32 (90%), Positives = 30/32 (93%)
Query: 1605 QQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAA 80
Score = 58.5 bits (140), Expect = 5e-08
Identities = 29/33 (87%), Positives = 30/33 (90%)
Query: 1604 QQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAA 81
Score = 58.2 bits (139), Expect = 7e-08
Identities = 29/34 (85%), Positives = 30/34 (88%)
Query: 1603 QQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAA 82
Score = 57.8 bits (138), Expect = 9e-08
Identities = 29/35 (82%), Positives = 30/35 (85%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAA 83
Score = 56.2 bits (134), Expect = 3e-07
Identities = 30/56 (53%), Positives = 36/56 (64%)
Query: 1607 QQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK 1662
QQQQQQQQQQQQQQQQQQQQQQ AAA AA + +A H +T+++
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVE 104
Score = 55.5 bits (132), Expect = 4e-07
Identities = 28/35 (80%), Positives = 29/35 (82%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 50 QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAA 84
Score = 53.1 bits (126), Expect = 2e-06
Identities = 27/35 (77%), Positives = 28/35 (80%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 51 QQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAA 85
Score = 52.0 bits (123), Expect = 5e-06
Identities = 28/45 (62%), Positives = 29/45 (64%)
Query: 1597 ARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPP 1641
A QQQQQQQQQQQQQQQQQQQQ+ AAAA AA P
Sbjct: 47 AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVP 91
Score = 40.4 bits (93), Expect = 0.014
Identities = 22/50 (44%), Positives = 25/50 (50%)
Query: 1592 AEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPP 1641
A + + QQQQQQQQQQQQQQQ+ AAAA PP
Sbjct: 47 AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPP 96
Score = 38.5 bits (88), Expect = 0.055
Identities = 22/61 (36%), Positives = 30/61 (49%)
Query: 1591 AAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVM 1650
AA++ + QQQQQQQQQQQQQQ+ AAAA P + T ++
Sbjct: 47 AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEII 106
Query: 1651 S 1651
+
Sbjct: 107 A 107
Score = 33.5 bits (75), Expect = 1.8
Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 6/53 (11%)
Query: 1588 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1640
++ A ++ + QQQQQQ QQQQQQQ+ AAAA AA P
Sbjct: 45 VVAAQQQQQQQQQQQQQQQQ------QQQQQQQEAAAAAAAAAAAAAAAAAVP 91
>gi|66934969 runt-related transcription factor 2 isoform c [Homo
sapiens]
Length = 507
Score = 58.9 bits (141), Expect = 4e-08
Identities = 29/32 (90%), Positives = 30/32 (93%)
Query: 1605 QQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 35 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAA 66
Score = 58.5 bits (140), Expect = 5e-08
Identities = 29/33 (87%), Positives = 30/33 (90%)
Query: 1604 QQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 35 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAA 67
Score = 58.2 bits (139), Expect = 7e-08
Identities = 29/34 (85%), Positives = 30/34 (88%)
Query: 1603 QQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 35 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAA 68
Score = 57.8 bits (138), Expect = 9e-08
Identities = 29/35 (82%), Positives = 30/35 (85%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 35 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAA 69
Score = 56.2 bits (134), Expect = 3e-07
Identities = 30/56 (53%), Positives = 36/56 (64%)
Query: 1607 QQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK 1662
QQQQQQQQQQQQQQQQQQQQQQ AAA AA + +A H +T+++
Sbjct: 35 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVE 90
Score = 55.5 bits (132), Expect = 4e-07
Identities = 28/35 (80%), Positives = 29/35 (82%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 36 QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAA 70
Score = 53.1 bits (126), Expect = 2e-06
Identities = 27/35 (77%), Positives = 28/35 (80%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 37 QQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAA 71
Score = 52.0 bits (123), Expect = 5e-06
Identities = 28/45 (62%), Positives = 29/45 (64%)
Query: 1597 ARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPP 1641
A QQQQQQQQQQQQQQQQQQQQ+ AAAA AA P
Sbjct: 33 AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVP 77
Score = 40.4 bits (93), Expect = 0.014
Identities = 22/50 (44%), Positives = 25/50 (50%)
Query: 1592 AEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPP 1641
A + + QQQQQQQQQQQQQQQ+ AAAA PP
Sbjct: 33 AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPP 82
Score = 38.5 bits (88), Expect = 0.055
Identities = 22/61 (36%), Positives = 30/61 (49%)
Query: 1591 AAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVM 1650
AA++ + QQQQQQQQQQQQQQ+ AAAA P + T ++
Sbjct: 33 AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEII 92
Query: 1651 S 1651
+
Sbjct: 93 A 93
Score = 33.5 bits (75), Expect = 1.8
Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 6/53 (11%)
Query: 1588 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1640
++ A ++ + QQQQQQ QQQQQQQ+ AAAA AA P
Sbjct: 31 VVAAQQQQQQQQQQQQQQQQ------QQQQQQQEAAAAAAAAAAAAAAAAAVP 77
>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
sapiens]
Length = 443
Score = 58.5 bits (140), Expect = 5e-08
Identities = 33/57 (57%), Positives = 37/57 (64%), Gaps = 1/57 (1%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP-PGSPTSATVMSTFTHSL 1657
QQQ QQQQQQQQQQQQQQQQQQQQQ+ AA HP PG+ SA + S+
Sbjct: 125 QQQHQQQQQQQQQQQQQQQQQQQQQRPPHLVHHAANHHPGPGAWRSAAAAAHLPPSM 181
Score = 31.2 bits (69), Expect = 8.8
Identities = 21/61 (34%), Positives = 25/61 (40%), Gaps = 3/61 (4%)
Query: 1589 LRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAA---AGAATEHPPGSPT 1645
L+ + + QQQQQQQQQQQQQ+ A A AA PP
Sbjct: 124 LQQQHQQQQQQQQQQQQQQQQQQQQQRPPHLVHHAANHHPGPGAWRSAAAAAHLPPSMGA 183
Query: 1646 S 1646
S
Sbjct: 184 S 184
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 58.5 bits (140), Expect = 5e-08
Identities = 29/41 (70%), Positives = 31/41 (75%)
Query: 1600 LNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1640
L QQQQQQQQQQQQQQQQQQQQQQQQQQQ + + P
Sbjct: 2717 LRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVP 2757
Score = 55.8 bits (133), Expect = 3e-07
Identities = 27/30 (90%), Positives = 27/30 (90%)
Query: 1598 RNLNQQQQQQQQQQQQQQQQQQQQQQQQQQ 1627
R QQQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 2718 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 2747
Score = 55.5 bits (132), Expect = 4e-07
Identities = 27/29 (93%), Positives = 28/29 (96%)
Query: 1600 LNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
L +QQQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 2716 LLRQQQQQQQQQQQQQQQQQQQQQQQQQQ 2744
Score = 49.7 bits (117), Expect = 2e-05
Identities = 24/27 (88%), Positives = 25/27 (92%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
Q +QQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 2715 QLLRQQQQQQQQQQQQQQQQQQQQQQQ 2741
Score = 48.9 bits (115), Expect = 4e-05
Identities = 36/98 (36%), Positives = 50/98 (51%), Gaps = 5/98 (5%)
Query: 1541 LAAITGSFQVLSSL--IETFVRLVFIVRSEAQRQELLAKVEEVVRNYTFLLRAAEESTAR 1598
+ ++T S V ++L ++T R + S+A +L K + F L ++ +
Sbjct: 2669 VTSVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKT---ITPAHFQLLRQQQQQQQ 2725
Query: 1599 NLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636
QQQQQQQQQQQQQQQQQQQ Q QV G A
Sbjct: 2726 QQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQA 2763
Score = 36.2 bits (82), Expect = 0.27
Identities = 22/55 (40%), Positives = 26/55 (47%), Gaps = 8/55 (14%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQ--------QQQQQQQQQQQQVAAAAGAATEH 1639
++ + QQQQQQQQQQQQQQ Q Q Q Q Q+ A EH
Sbjct: 2725 QQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEH 2779
Score = 32.7 bits (73), Expect = 3.0
Identities = 103/560 (18%), Positives = 198/560 (35%), Gaps = 52/560 (9%)
Query: 535 PCASRARSYTLDNSLGAEALNFYCDSCKAKLQSSXGPSQSGKPGSSRDNILLYDEIPVTL 594
P + + + ++ G A F S +L S P PG S +++ + P
Sbjct: 2589 PTGAVSGNVIVNTIAGVPAATF--QSINKRLASPVAPGALTTPGGSAPAQVVHTQPPPRA 2646
Query: 595 IDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPPPPQTAGLIVLATITPESSLD 654
+ S T T D ++T Q + A+ + T ++ P+ S
Sbjct: 2647 VGSPATATP-------DLVSMATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQA 2699
Query: 655 SGHETNSSELTDM------SEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAA 708
+G + +T + +Q Q Q + + ++Q
Sbjct: 2700 TGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQI 2759
Query: 709 QAVLTAPYSL---GRPDPNPSL----QPIATGQSPGPPGARRKLPQSEGQVQGERTYSLA 761
Q +P + G+ P + Q + P PP A+ PQ QVQ
Sbjct: 2760 QGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQ-------- 2811
Query: 762 VHPALSPQLSEQKNLSLLSPVPEDKGPGHTRAGLEMS--LRAATSSLSEEQVSELRDNLP 819
V + PQ + ++ +P P G T A L+++ R TS L + + + P
Sbjct: 2812 VQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQP 2871
Query: 820 KEVRLSPKLILDPKSSVTPAIISA-ALQQVVHNKSLVTAGGALGNPPSRGERRLEASMGR 878
+V L+ P SV A++S+ + + N + ++ A+G P + + A
Sbjct: 2872 AQVALAK----PPVVSVPAAVVSSPGVTTLPMNVAGISV--AIGQPQKAAGQTVVAQPVH 2925
Query: 879 PEVSMMSSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAPTG-SRADSLHLSQQED 937
+ + + + I P A + Q ++ A+ ++P A + A L Q
Sbjct: 2926 MQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFL 2985
Query: 938 SLPVQNFPPKSYLLRTSRESVGKQATGEVAGKGGPVGGKPTLQKQGTISSQGEKAQLEST 997
+ P+ K + + + +V + PV ++Q+ + S Q + T
Sbjct: 2986 TTPISQ-AQKLAGAQQVQTQIQVAKLPQVVQQQTPVA---SIQQVASASQQASPQTVALT 3041
Query: 998 PKRSKLEETSLVPRAT-----YPMALQSPSCQSRSHSPSCQPHGHSPSS-QSRGQSPSCQ 1051
+ ++ ++P T L + + +P P +P+ + SPS Q
Sbjct: 3042 QATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQVPASSDSPSQQ 3101
Query: 1052 PRGQSPLRSQAASRQVSTMP 1071
P+ Q +R A + T P
Sbjct: 3102 PKLQ--MRVPAVRLKTPTKP 3119
>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
Length = 1161
Score = 58.2 bits (139), Expect = 7e-08
Identities = 28/31 (90%), Positives = 30/31 (96%)
Query: 1598 RNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
R+ +QQQQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 456 RHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQ 486
Score = 49.3 bits (116), Expect = 3e-05
Identities = 23/28 (82%), Positives = 25/28 (89%)
Query: 1601 NQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
++ QQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 455 HRHPHQQQQQQQQQQQQQQQQQQQQQQQ 482
Score = 48.9 bits (115), Expect = 4e-05
Identities = 23/30 (76%), Positives = 25/30 (83%)
Query: 1599 NLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
+L + QQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 452 HLQHRHPHQQQQQQQQQQQQQQQQQQQQQQ 481
Score = 46.6 bits (109), Expect = 2e-04
Identities = 22/31 (70%), Positives = 25/31 (80%)
Query: 1598 RNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
+ L+ Q + QQQQQQQQQQQQQQQQQQQQ
Sbjct: 449 QQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQ 479
Score = 42.0 bits (97), Expect = 0.005
Identities = 20/40 (50%), Positives = 23/40 (57%)
Query: 1590 RAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQV 1629
R + + QQQQQQQQQQQQQQQQQQQ +
Sbjct: 456 RHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHL 495
Score = 41.2 bits (95), Expect = 0.008
Identities = 20/29 (68%), Positives = 21/29 (72%)
Query: 1600 LNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
L Q Q + QQQQQQQQQQQQQQQQQ
Sbjct: 448 LQQLHLQHRHPHQQQQQQQQQQQQQQQQQ 476
Score = 40.0 bits (92), Expect = 0.019
Identities = 20/47 (42%), Positives = 25/47 (53%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEH 1639
++ + QQQQQQQQQQQQQQQQQQ + A +H
Sbjct: 460 QQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQH 506
Score = 32.3 bits (72), Expect = 3.9
Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 21/73 (28%)
Query: 1593 EESTARNLNQQQQQQQQQQQQ---------------------QQQQQQQQQQQQQQQVAA 1631
++ + QQQQQQQQQQQQ QQQQ QQQ V
Sbjct: 466 QQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQ 525
Query: 1632 AAGAATEHPPGSP 1644
+A+++P P
Sbjct: 526 PQPSASQYPTMMP 538
>gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens]
Length = 662
Score = 58.2 bits (139), Expect = 7e-08
Identities = 28/31 (90%), Positives = 30/31 (96%)
Query: 1598 RNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
R+ +QQQQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 456 RHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQ 486
Score = 49.3 bits (116), Expect = 3e-05
Identities = 23/28 (82%), Positives = 25/28 (89%)
Query: 1601 NQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
++ QQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 455 HRHPHQQQQQQQQQQQQQQQQQQQQQQQ 482
Score = 48.9 bits (115), Expect = 4e-05
Identities = 23/30 (76%), Positives = 25/30 (83%)
Query: 1599 NLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
+L + QQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 452 HLQHRHPHQQQQQQQQQQQQQQQQQQQQQQ 481
Score = 46.6 bits (109), Expect = 2e-04
Identities = 22/31 (70%), Positives = 25/31 (80%)
Query: 1598 RNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
+ L+ Q + QQQQQQQQQQQQQQQQQQQQ
Sbjct: 449 QQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQ 479
Score = 42.0 bits (97), Expect = 0.005
Identities = 20/40 (50%), Positives = 23/40 (57%)
Query: 1590 RAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQV 1629
R + + QQQQQQQQQQQQQQQQQQQ +
Sbjct: 456 RHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHL 495
Score = 41.2 bits (95), Expect = 0.008
Identities = 20/29 (68%), Positives = 21/29 (72%)
Query: 1600 LNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
L Q Q + QQQQQQQQQQQQQQQQQ
Sbjct: 448 LQQLHLQHRHPHQQQQQQQQQQQQQQQQQ 476
Score = 40.0 bits (92), Expect = 0.019
Identities = 20/47 (42%), Positives = 25/47 (53%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEH 1639
++ + QQQQQQQQQQQQQQQQQQ + A +H
Sbjct: 460 QQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQH 506
Score = 32.3 bits (72), Expect = 3.9
Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 21/73 (28%)
Query: 1593 EESTARNLNQQQQQQQQQQQQ---------------------QQQQQQQQQQQQQQQVAA 1631
++ + QQQQQQQQQQQQ QQQQ QQQ V
Sbjct: 466 QQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQ 525
Query: 1632 AAGAATEHPPGSP 1644
+A+++P P
Sbjct: 526 PQPSASQYPTMMP 538
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 57.0 bits (136), Expect = 1e-07
Identities = 28/33 (84%), Positives = 29/33 (87%)
Query: 1599 NLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAA 1631
N Q QQQQQQQQQQQQQQQQQQQQQQQQQ+ A
Sbjct: 256 NFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQA 288
Score = 55.5 bits (132), Expect = 4e-07
Identities = 28/41 (68%), Positives = 29/41 (70%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPG 1642
QQQQQQQQQQQQQQQQQQQQQQQQQ Q + P G
Sbjct: 261 QQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQG 301
Score = 53.5 bits (127), Expect = 2e-06
Identities = 28/44 (63%), Positives = 29/44 (65%)
Query: 1601 NQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSP 1644
N Q QQQQQQQQQQQQQQQQQQQQQQQ A +H P
Sbjct: 256 NFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQP 299
Score = 47.8 bits (112), Expect = 9e-05
Identities = 24/34 (70%), Positives = 25/34 (73%)
Query: 1595 STARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
S R +N Q QQQQQQQQQQQQQQQQQQQQ
Sbjct: 247 SVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQ 280
Score = 43.9 bits (102), Expect = 0.001
Identities = 22/45 (48%), Positives = 28/45 (62%)
Query: 1584 NYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
N+ L + ++ + QQQQQQQQQQQQ Q + QQ QQQQ Q
Sbjct: 256 NFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQ 300
Score = 42.7 bits (99), Expect = 0.003
Identities = 22/48 (45%), Positives = 28/48 (58%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1640
++ + QQQQQQQQQQQ Q + QQ QQQQ Q + A T+ P
Sbjct: 266 QQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVP 313
Score = 40.4 bits (93), Expect = 0.014
Identities = 96/490 (19%), Positives = 170/490 (34%), Gaps = 93/490 (18%)
Query: 618 LQALEALAASEDGPHPPPPQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMS-AMKQ 676
LQA +LA + HPPPP G S S TN ++++ + + MK
Sbjct: 357 LQARPSLATVQTPSHPPPPYPFG----------SQQASQAHTNFPQMSNPGQFTAPQMKS 406
Query: 677 HQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNPSLQPIATGQSP 736
Q + L + L + + A + + G P +P++ P
Sbjct: 407 LQGGPSRVPTPLQQPHLTNK-----------SPASSPSSFQQGSPASSPTVNQTQQQMGP 455
Query: 737 GPPGARRKLPQSEGQVQGERTYSLAVHPALSPQLSE---QKNLSLLSPVPEDKGPGHTRA 793
PP LPQ Q P +P + + N ++ P ++GP
Sbjct: 456 RPP-QNNPLPQGFQQPVSS--------PGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHP 506
Query: 794 GLEMSLRAATSSLSEEQVSE--LRDNLPKEVRLSPKLILDPKSSVTPAIISAALQQVVHN 851
GL + S Q + ++ +P +P ++ Q+ N
Sbjct: 507 GLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPG--------------NSGAPQLQAN 552
Query: 852 KSLVTAGGALGNPPSRGERRLEASMGRPEV---SMMSSSASKNLKFKISPSAPETSWN-- 906
+++ AGG PP + +++ S G P + S+M + N + + P+ + +
Sbjct: 553 QNVQHAGGQGAGPP---QNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNM 609
Query: 907 ---------------------SQHQLGAEVSS-SPRAP-TGSRADSLHLSQQEDSLPVQN 943
SQ Q+ + + +P+ P SRA + Q + P QN
Sbjct: 610 QGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQN 669
Query: 944 FPPKSYLLRTSRESVGKQATGEVAGKG---GPVG-----GKPTLQKQGTISSQGEKAQLE 995
P + ++ + +Q +A GP G P +++ T QG K Q
Sbjct: 670 LGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFN 729
Query: 996 STPKRSKLEETSLVPRATYP----MALQSPSCQSRSHSPSCQPHGHSPSSQSRGQSPSCQ 1051
+ + + + + + R P +Q S P P +SPS Q +
Sbjct: 730 TQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLR 789
Query: 1052 PRGQSPLRSQ 1061
P G SP +Q
Sbjct: 790 PPGPSPHMAQ 799
Score = 38.9 bits (89), Expect = 0.042
Identities = 21/50 (42%), Positives = 26/50 (52%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPG 1642
++ + QQQQQQQQQ Q + QQ QQQQ Q + A PPG
Sbjct: 268 QQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPG 317
Score = 35.8 bits (81), Expect = 0.36
Identities = 33/147 (22%), Positives = 66/147 (44%), Gaps = 8/147 (5%)
Query: 1012 ATYPMALQSPSCQSRSHSPSCQPHGHSPSSQ--SRGQSPSCQPRGQSPLRSQAASRQVST 1069
A +PMA + + + P G + SS + G +P QPR P A + +
Sbjct: 163 AGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLS 222
Query: 1070 MPSRKLETTLNGAHSTSEGPAKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQ 1129
+ ++ +G+ + P +P S R + A FP Q+++ ++Q Q Q+ +Q
Sbjct: 223 GLHIQQQSHPSGSLAPPHHPMQPVSVN-----RQMNPANFPQLQQQQQQQQQQQQQQQQQ 277
Query: 1130 YELEFLEEL-LKPPSQGELPGTEYLQP 1155
+ + ++L +PP Q + + ++P
Sbjct: 278 QQQQQQQQLQARPPQQHQQQQPQGIRP 304
Score = 35.8 bits (81), Expect = 0.36
Identities = 22/52 (42%), Positives = 24/52 (46%), Gaps = 7/52 (13%)
Query: 1600 LNQQQQQQQQQQQQQQQQQQQQQQ-------QQQQQVAAAAGAATEHPPGSP 1644
L QQQQ Q Q QQQQQQQQQ QQ + + HPP P
Sbjct: 1009 LPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGP 1060
Score = 35.4 bits (80), Expect = 0.46
Identities = 20/32 (62%), Positives = 21/32 (65%), Gaps = 4/32 (12%)
Query: 1602 QQQQQQQQQQQQQ----QQQQQQQQQQQQQQV 1629
QQQ Q Q QQQQ Q Q QQQQQQQQQ+
Sbjct: 1002 QQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQM 1033
Score = 33.1 bits (74), Expect = 2.3
Identities = 19/33 (57%), Positives = 20/33 (60%), Gaps = 5/33 (15%)
Query: 1602 QQQQQQQQQQQQ-----QQQQQQQQQQQQQQQV 1629
QQ Q Q QQQQ Q Q QQQQQQQQQ +
Sbjct: 1003 QQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMM 1035
>gi|38158015 mastermind-like 3 [Homo sapiens]
Length = 1133
Score = 56.6 bits (135), Expect = 2e-07
Identities = 30/59 (50%), Positives = 38/59 (64%), Gaps = 3/59 (5%)
Query: 1589 LRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSA 1647
+ A ++ A+ + Q+QQQQQQQQQQQQQQQQQQQQQ Q + + PP SP A
Sbjct: 471 MAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLG---PPSSPYGA 526
Score = 52.4 bits (124), Expect = 4e-06
Identities = 33/64 (51%), Positives = 40/64 (62%), Gaps = 8/64 (12%)
Query: 1591 AAEESTARNLNQ---QQQQ-----QQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPG 1642
+++ S A L Q QQQQ QQ+QQQQQQQQQQQQQQQQQQQ + + P G
Sbjct: 459 SSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLG 518
Query: 1643 SPTS 1646
P+S
Sbjct: 519 PPSS 522
Score = 41.6 bits (96), Expect = 0.006
Identities = 21/33 (63%), Positives = 23/33 (69%)
Query: 1606 QQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATE 1638
QQQQQQQQQQQQQQQQQQ Q+ A +E
Sbjct: 629 QQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSE 661
Score = 41.6 bits (96), Expect = 0.006
Identities = 21/29 (72%), Positives = 21/29 (72%)
Query: 1604 QQQQQQQQQQQQQQQQQQQQQQQQQVAAA 1632
QQQQQQQQQQQQQQQQQQ Q Q A
Sbjct: 629 QQQQQQQQQQQQQQQQQQPPPPQLQAPRA 657
Score = 40.8 bits (94), Expect = 0.011
Identities = 20/25 (80%), Positives = 20/25 (80%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQ 1626
QQQQQQQQQQQQQQQQQQ Q Q
Sbjct: 629 QQQQQQQQQQQQQQQQQQPPPPQLQ 653
Score = 40.8 bits (94), Expect = 0.011
Identities = 20/25 (80%), Positives = 20/25 (80%)
Query: 1603 QQQQQQQQQQQQQQQQQQQQQQQQQ 1627
QQQQQQQQQQQQQQQQQQ Q Q
Sbjct: 629 QQQQQQQQQQQQQQQQQQPPPPQLQ 653
Score = 40.4 bits (93), Expect = 0.014
Identities = 21/29 (72%), Positives = 21/29 (72%)
Query: 1605 QQQQQQQQQQQQQQQQQQQQQQQQVAAAA 1633
QQQQQQQQQQQQQQQQQQ Q A A
Sbjct: 629 QQQQQQQQQQQQQQQQQQPPPPQLQAPRA 657
Score = 40.0 bits (92), Expect = 0.019
Identities = 20/29 (68%), Positives = 21/29 (72%)
Query: 1599 NLNQQQQQQQQQQQQQQQQQQQQQQQQQQ 1627
N N+ QQQQQQQQQQQQQQQQQQ
Sbjct: 618 NPNKNPLMPYIQQQQQQQQQQQQQQQQQQ 646
Score = 39.7 bits (91), Expect = 0.025
Identities = 19/26 (73%), Positives = 20/26 (76%)
Query: 1600 LNQQQQQQQQQQQQQQQQQQQQQQQQ 1625
+ QQQQQQQQQQQQQQQQQ Q Q
Sbjct: 628 IQQQQQQQQQQQQQQQQQQPPPPQLQ 653
Score = 37.0 bits (84), Expect = 0.16
Identities = 19/42 (45%), Positives = 26/42 (61%)
Query: 1600 LNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPP 1641
L Q+ Q +QQ+QQ ++Q+QQQQQQQQ+ A H P
Sbjct: 739 LIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLP 780
Score = 35.4 bits (80), Expect = 0.46
Identities = 20/56 (35%), Positives = 24/56 (42%)
Query: 1589 LRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSP 1644
L ++ + QQQQQQQQQQQQQ Q + A T P SP
Sbjct: 481 LMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSP 536
Score = 35.0 bits (79), Expect = 0.61
Identities = 17/35 (48%), Positives = 25/35 (71%)
Query: 1594 ESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
+ A+ + QQ+QQ ++Q+QQQQQQQQ +QQ Q
Sbjct: 741 DQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQ 775
Score = 34.7 bits (78), Expect = 0.79
Identities = 18/38 (47%), Positives = 22/38 (57%)
Query: 1591 AAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
A S Q +Q QQQQ+ + QQ+QQQQQQQQ
Sbjct: 456 AVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQ 493
Score = 32.7 bits (73), Expect = 3.0
Identities = 18/56 (32%), Positives = 28/56 (50%)
Query: 1562 VFIVRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQ 1617
V + S+ E L ++ + L++ ++ + QQQQQQQQQQQQ Q
Sbjct: 455 VAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQ 510
Score = 32.7 bits (73), Expect = 3.0
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQV 1629
E+ + L +Q+QQQQQQQQ +QQ QQ +Q +
Sbjct: 748 EQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHL 784
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 56.2 bits (134), Expect = 3e-07
Identities = 32/63 (50%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Query: 1565 VRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQ 1624
+R++ ++LA+ + + T L + T L QQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 182 LRAQILAYKMLARGQPLPE--TLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQP 239
Query: 1625 QQQ 1627
QQQ
Sbjct: 240 QQQ 242
Score = 54.3 bits (129), Expect = 1e-06
Identities = 26/27 (96%), Positives = 26/27 (96%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
QQQQQQQQQQQQQQQQQQQQQQQ QQQ
Sbjct: 216 QQQQQQQQQQQQQQQQQQQQQQQPQQQ 242
Score = 51.6 bits (122), Expect = 6e-06
Identities = 26/31 (83%), Positives = 26/31 (83%)
Query: 1598 RNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
R L QQQQQQQQQQQQQQQQQQQQQQQ Q
Sbjct: 210 RTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQ 240
Score = 48.5 bits (114), Expect = 5e-05
Identities = 31/78 (39%), Positives = 38/78 (48%)
Query: 1569 AQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
A+ Q L ++ V+ L ++ + QQQQQQQQQQQQQ QQQ Q Q QQQQ
Sbjct: 193 ARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQ 252
Query: 1629 VAAAAGAATEHPPGSPTS 1646
A PG S
Sbjct: 253 QPALVNYNRPSGPGPELS 270
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 56.2 bits (134), Expect = 3e-07
Identities = 32/63 (50%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Query: 1565 VRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQ 1624
+R++ ++LA+ + + T L + T L QQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 182 LRAQILAYKMLARGQPLPE--TLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQP 239
Query: 1625 QQQ 1627
QQQ
Sbjct: 240 QQQ 242
Score = 54.3 bits (129), Expect = 1e-06
Identities = 26/27 (96%), Positives = 26/27 (96%)
Query: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
QQQQQQQQQQQQQQQQQQQQQQQ QQQ
Sbjct: 216 QQQQQQQQQQQQQQQQQQQQQQQPQQQ 242
Score = 51.6 bits (122), Expect = 6e-06
Identities = 26/31 (83%), Positives = 26/31 (83%)
Query: 1598 RNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
R L QQQQQQQQQQQQQQQQQQQQQQQ Q
Sbjct: 210 RTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQ 240
Score = 48.5 bits (114), Expect = 5e-05
Identities = 31/78 (39%), Positives = 38/78 (48%)
Query: 1569 AQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
A+ Q L ++ V+ L ++ + QQQQQQQQQQQQQ QQQ Q Q QQQQ
Sbjct: 193 ARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQ 252
Query: 1629 VAAAAGAATEHPPGSPTS 1646
A PG S
Sbjct: 253 QPALVNYNRPSGPGPELS 270
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 55.8 bits (133), Expect = 3e-07
Identities = 45/164 (27%), Positives = 73/164 (44%), Gaps = 11/164 (6%)
Query: 1491 RQCVASPEARAPKPYV----SQISEYKLELA----LKFKELRASCRRVANVDKSPTHMLA 1542
R + PE AP P Q E K +A LK K + + V +P+
Sbjct: 1159 RPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAK 1218
Query: 1543 AITGSFQVLSSLIETFVRLVFIVRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQ 1602
+ + SF+ ++++A+ E K +E +R R E++ +
Sbjct: 1219 SSSDSFEQFRRAAREKEEREKALKAQAEHAE---KEKERLRQERMRSREDEDALEQARRA 1275
Query: 1603 QQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTS 1646
++ +++Q+QQQQQ+Q+QQQQQQQQ A AA A + P S
Sbjct: 1276 HEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQS 1319
Score = 32.7 bits (73), Expect = 3.0
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 23/71 (32%)
Query: 1590 RAAEESTARNLNQQQQQQQQQQQQQ-----------------------QQQQQQQQQQQQ 1626
RA EE+ R QQQQ+Q+QQQQQQ QQ++ ++++Q
Sbjct: 1274 RAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQ 1333
Query: 1627 QQVAAAAGAAT 1637
++ A AAT
Sbjct: 1334 ERRRREAMAAT 1344
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,857,242
Number of Sequences: 37866
Number of extensions: 3489286
Number of successful extensions: 33149
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 331
Number of HSP's successfully gapped in prelim test: 424
Number of HSP's that attempted gapping in prelim test: 18243
Number of HSP's gapped (non-prelim): 7371
length of query: 1662
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1546
effective length of database: 13,855,062
effective search space: 21419925852
effective search space used: 21419925852
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.