Guide to the Human Genome
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Search of human proteins with 239756464

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239756464 PREDICTED: hypothetical protein LOC197350 [Homo
sapiens]
         (432 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239756464 PREDICTED: hypothetical protein LOC197350 [Homo sap...   881   0.0  
gi|169210653 PREDICTED: hypothetical protein LOC197350 [Homo sap...   880   0.0  
gi|6912286 caspase 14 precursor [Homo sapiens]                        173   3e-43
gi|39995059 caspase 2 isoform 1 preproprotein [Homo sapiens]           75   2e-13
gi|122056476 caspase 8 isoform G precursor [Homo sapiens]              71   2e-12
gi|122056474 caspase 8 isoform C precursor [Homo sapiens]              71   2e-12
gi|15718708 caspase 8 isoform C precursor [Homo sapiens]               71   2e-12
gi|15718706 caspase 8 isoform B precursor [Homo sapiens]               71   2e-12
gi|15718704 caspase 8 isoform A precursor [Homo sapiens]               71   2e-12
gi|14916483 caspase 6 isoform alpha preproprotein [Homo sapiens]       71   2e-12
gi|14790124 caspase 9 isoform alpha preproprotein [Homo sapiens]       66   5e-11
gi|14916485 caspase 6 isoform beta [Homo sapiens]                      65   9e-11
gi|15718698 caspase 7 isoform delta [Homo sapiens]                     65   1e-10
gi|15718700 caspase 7 isoform alpha [Homo sapiens]                     65   1e-10
gi|4502581 caspase 7 isoform alpha precursor [Homo sapiens]            65   1e-10
gi|14790115 caspase 3 preproprotein [Homo sapiens]                     63   6e-10
gi|14790119 caspase 3 preproprotein [Homo sapiens]                     63   6e-10
gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens]          55   9e-08
gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens]          55   9e-08
gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens]          49   9e-06
gi|15431332 caspase 1 isoform delta [Homo sapiens]                     47   4e-05
gi|15431330 caspase 1 isoform gamma precursor [Homo sapiens]           45   2e-04
gi|15431328 caspase 1 isoform alpha precursor [Homo sapiens]           45   2e-04
gi|4502573 caspase 1 isoform beta precursor [Homo sapiens]             45   2e-04
gi|15451910 caspase 4 isoform gamma precursor [Homo sapiens]           44   2e-04
gi|4502577 caspase 4 isoform alpha precursor [Homo sapiens]            44   2e-04
gi|209870079 caspase 5 isoform f precursor [Homo sapiens]              42   0.001
gi|209870073 caspase 5 isoform c [Homo sapiens]                        42   0.001
gi|209870071 caspase 5 isoform b precursor [Homo sapiens]              42   0.001
gi|209870069 caspase 5 isoform a precursor [Homo sapiens]              42   0.001

>gi|239756464 PREDICTED: hypothetical protein LOC197350 [Homo
           sapiens]
          Length = 432

 Score =  881 bits (2276), Expect = 0.0
 Identities = 432/432 (100%), Positives = 432/432 (100%)

Query: 1   MAFLVAGTLRLATQMADTRDSLGRKLREEGGPGPGLPRGTGLVPGAAGCPRAPCGVCLSG 60
           MAFLVAGTLRLATQMADTRDSLGRKLREEGGPGPGLPRGTGLVPGAAGCPRAPCGVCLSG
Sbjct: 1   MAFLVAGTLRLATQMADTRDSLGRKLREEGGPGPGLPRGTGLVPGAAGCPRAPCGVCLSG 60

Query: 61  LDAPRGQLRQPQQLVRELSGCRALRGCPRVFLLLSSGPGSSLEPGAFLAGLRELCGRSPH 120
           LDAPRGQLRQPQQLVRELSGCRALRGCPRVFLLLSSGPGSSLEPGAFLAGLRELCGRSPH
Sbjct: 61  LDAPRGQLRQPQQLVRELSGCRALRGCPRVFLLLSSGPGSSLEPGAFLAGLRELCGRSPH 120

Query: 121 WSLVQLLTELFRRVAEESAGGTCCPVLRSSLRGALCLGGVEPWRPEPAPGPSTQYDLSKA 180
           WSLVQLLTELFRRVAEESAGGTCCPVLRSSLRGALCLGGVEPWRPEPAPGPSTQYDLSKA
Sbjct: 121 WSLVQLLTELFRRVAEESAGGTCCPVLRSSLRGALCLGGVEPWRPEPAPGPSTQYDLSKA 180

Query: 181 RAALLLAVIQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRG 240
           RAALLLAVIQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRG
Sbjct: 181 RAALLLAVIQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRG 240

Query: 241 PVSCALVALMAHGGPRGQLLGADGQEVQPEALMQELSRCQVLQGRPKIFLLQACRGGNRD 300
           PVSCALVALMAHGGPRGQLLGADGQEVQPEALMQELSRCQVLQGRPKIFLLQACRGGNRD
Sbjct: 241 PVSCALVALMAHGGPRGQLLGADGQEVQPEALMQELSRCQVLQGRPKIFLLQACRGGNRD 300

Query: 301 AGVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAE 360
           AGVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAE
Sbjct: 301 AGVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAE 360

Query: 361 GYVAYRDDKGSDFIQTLVEVLRANPGRDLLELLTEVNRRVCEQEVLGPDCDELRKACLEI 420
           GYVAYRDDKGSDFIQTLVEVLRANPGRDLLELLTEVNRRVCEQEVLGPDCDELRKACLEI
Sbjct: 361 GYVAYRDDKGSDFIQTLVEVLRANPGRDLLELLTEVNRRVCEQEVLGPDCDELRKACLEI 420

Query: 421 RSSLRRRLCLQA 432
           RSSLRRRLCLQA
Sbjct: 421 RSSLRRRLCLQA 432


>gi|169210653 PREDICTED: hypothetical protein LOC197350 [Homo
           sapiens]
          Length = 432

 Score =  880 bits (2273), Expect = 0.0
 Identities = 431/432 (99%), Positives = 432/432 (100%)

Query: 1   MAFLVAGTLRLATQMADTRDSLGRKLREEGGPGPGLPRGTGLVPGAAGCPRAPCGVCLSG 60
           MAFLVAGTLRLATQMADTRDSLGRKLREEGGPGPGLPRGTGLVPGAAGCPRAPCGVCLSG
Sbjct: 1   MAFLVAGTLRLATQMADTRDSLGRKLREEGGPGPGLPRGTGLVPGAAGCPRAPCGVCLSG 60

Query: 61  LDAPRGQLRQPQQLVRELSGCRALRGCPRVFLLLSSGPGSSLEPGAFLAGLRELCGRSPH 120
           LDAPRGQLRQPQQLVRELSGCRALRGCP+VFLLLSSGPGSSLEPGAFLAGLRELCGRSPH
Sbjct: 61  LDAPRGQLRQPQQLVRELSGCRALRGCPKVFLLLSSGPGSSLEPGAFLAGLRELCGRSPH 120

Query: 121 WSLVQLLTELFRRVAEESAGGTCCPVLRSSLRGALCLGGVEPWRPEPAPGPSTQYDLSKA 180
           WSLVQLLTELFRRVAEESAGGTCCPVLRSSLRGALCLGGVEPWRPEPAPGPSTQYDLSKA
Sbjct: 121 WSLVQLLTELFRRVAEESAGGTCCPVLRSSLRGALCLGGVEPWRPEPAPGPSTQYDLSKA 180

Query: 181 RAALLLAVIQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRG 240
           RAALLLAVIQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRG
Sbjct: 181 RAALLLAVIQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRG 240

Query: 241 PVSCALVALMAHGGPRGQLLGADGQEVQPEALMQELSRCQVLQGRPKIFLLQACRGGNRD 300
           PVSCALVALMAHGGPRGQLLGADGQEVQPEALMQELSRCQVLQGRPKIFLLQACRGGNRD
Sbjct: 241 PVSCALVALMAHGGPRGQLLGADGQEVQPEALMQELSRCQVLQGRPKIFLLQACRGGNRD 300

Query: 301 AGVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAE 360
           AGVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAE
Sbjct: 301 AGVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAE 360

Query: 361 GYVAYRDDKGSDFIQTLVEVLRANPGRDLLELLTEVNRRVCEQEVLGPDCDELRKACLEI 420
           GYVAYRDDKGSDFIQTLVEVLRANPGRDLLELLTEVNRRVCEQEVLGPDCDELRKACLEI
Sbjct: 361 GYVAYRDDKGSDFIQTLVEVLRANPGRDLLELLTEVNRRVCEQEVLGPDCDELRKACLEI 420

Query: 421 RSSLRRRLCLQA 432
           RSSLRRRLCLQA
Sbjct: 421 RSSLRRRLCLQA 432


>gi|6912286 caspase 14 precursor [Homo sapiens]
          Length = 242

 Score =  173 bits (438), Expect = 3e-43
 Identities = 109/261 (41%), Positives = 152/261 (58%), Gaps = 32/261 (12%)

Query: 174 QYDLSKARAALLLAVIQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFRE 233
           +YD+S AR AL+L V + R G++ D++AL  +   L FE+T++ DPTA+ FQEEL +F++
Sbjct: 11  KYDMSGARLALILCVTKAREGSEEDLDALEHMFRQLRFESTMKRDPTAEQFQEELEKFQQ 70

Query: 234 QLDTCRGPVSCALVALMAHGGPRGQLLGADGQEVQPEALMQELS--RCQVLQGRPKIFLL 291
            +D+   PVSCA V LMAH G  G L G DG+ V+ E L + L+   CQ L+ +PK++++
Sbjct: 71  AIDSREDPVSCAFVVLMAH-GREGFLKGEDGEMVKLENLFEALNNKNCQALRAKPKVYII 129

Query: 292 QACRGGNRDAGVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQAD 351
           QACRG  RD G              +P ++P++ D L                       
Sbjct: 130 QACRGEQRDPGETVGGDEIVMVIKDSPQTIPTYTDALH---------------------- 167

Query: 352 ILTVYSAAEGYVAYR-DDKGSDFIQTLVEVLRANPGRDLLELLTEVNRRVCEQEVLGPDC 410
              VYS  EGY+AYR D KGS FIQTLV+V     G  +LELLTEV RR+ E E++    
Sbjct: 168 ---VYSTVEGYIAYRHDQKGSCFIQTLVDVFTKRKGH-ILELLTEVTRRMAEAELVQE-- 221

Query: 411 DELRKACLEIRSSLRRRLCLQ 431
            + RK   EI+S+LR+RL LQ
Sbjct: 222 GKARKTNPEIQSTLRKRLYLQ 242


>gi|39995059 caspase 2 isoform 1 preproprotein [Homo sapiens]
          Length = 452

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 74/259 (28%), Positives = 113/259 (43%), Gaps = 46/259 (17%)

Query: 189 IQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVA 248
           ++ R G   D   L  L   LG++  V  D TAQ  QE+L  F  QL   R   SC +VA
Sbjct: 216 LEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEMQEKLQNFA-QLPAHRVTDSC-IVA 273

Query: 249 LMAHGGPRGQLLGADGQEVQPEALMQ--ELSRCQVLQGRPKIFLLQACRGGNRDAGVGPT 306
           L++HG   G + G DG+ +Q + + Q  + + C  LQ +PK+F +QACRG   D GV   
Sbjct: 274 LLSHG-VEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNKPKMFFIQACRGDETDRGV--- 329

Query: 307 ALPWYWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSS--------DQADILTVYSA 358
                              D       A    C  +  G           ++D++  Y+ 
Sbjct: 330 -------------------DQQDGKNHAGSPGCEESDAGKEKLPKMRLPTRSDMICGYAC 370

Query: 359 AEGYVAYRDDK-GSDFIQTLVEVLRANP-GRDLLELLTEVNRRVCEQEVLGPD-----CD 411
            +G  A R+ K GS +I+ L +V         + ++L +VN  + ++E   P      C 
Sbjct: 371 LKGTAAMRNTKRGSWYIEALAQVFSERACDMHVADMLVKVNALIKDREGYAPGTEFHRCK 430

Query: 412 ELRKACLEIRSSLRRRLCL 430
           E+ + C    S+L R L L
Sbjct: 431 EMSEYC----STLCRHLYL 445


>gi|122056476 caspase 8 isoform G precursor [Homo sapiens]
          Length = 538

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 76/262 (29%), Positives = 118/262 (45%), Gaps = 37/262 (14%)

Query: 175 YDLSKARAAL-LLAVIQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFRE 233
           ++ +KAR  +  L  I+ R G   D  AL      L FE     D T +   E L  + +
Sbjct: 301 HNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIY-Q 359

Query: 234 QLDTCRGPVSCALVALMAHGGPRGQLLGADGQEVQPEALMQELS--RCQVLQGRPKIFLL 291
            +D     + C +  +++HG  +G + G DGQE     L  + +  +C  L G+PK+F +
Sbjct: 360 LMD--HSNMDCFICCILSHGD-KGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFI 416

Query: 292 QACRGGNRDAGVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSS--CRGTPPGSSDQ 349
           QAC+G N   G+              P    S     Q Y E   SS   R  P    D+
Sbjct: 417 QACQGDNYQKGI--------------PVETDSEE---QPYLEMDLSSPQTRYIP----DE 455

Query: 350 ADILTVYSAAEGYVAYRDD-KGSDFIQTLVEVLRAN--PGRDLLELLTEVNRRVCEQEVL 406
           AD L   +     V+YR+  +G+ +IQ+L + LR     G D+L +LTEVN  V  ++  
Sbjct: 456 ADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKD-- 513

Query: 407 GPDCDELRKACLEIRSSLRRRL 428
             D   + K   +   +LR++L
Sbjct: 514 --DKKNMGKQMPQPTFTLRKKL 533


>gi|122056474 caspase 8 isoform C precursor [Homo sapiens]
          Length = 464

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 76/262 (29%), Positives = 118/262 (45%), Gaps = 37/262 (14%)

Query: 175 YDLSKARAAL-LLAVIQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFRE 233
           ++ +KAR  +  L  I+ R G   D  AL      L FE     D T +   E L  + +
Sbjct: 227 HNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIY-Q 285

Query: 234 QLDTCRGPVSCALVALMAHGGPRGQLLGADGQEVQPEALMQELS--RCQVLQGRPKIFLL 291
            +D     + C +  +++HG  +G + G DGQE     L  + +  +C  L G+PK+F +
Sbjct: 286 LMD--HSNMDCFICCILSHGD-KGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFI 342

Query: 292 QACRGGNRDAGVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSS--CRGTPPGSSDQ 349
           QAC+G N   G+              P    S     Q Y E   SS   R  P    D+
Sbjct: 343 QACQGDNYQKGI--------------PVETDSEE---QPYLEMDLSSPQTRYIP----DE 381

Query: 350 ADILTVYSAAEGYVAYRDD-KGSDFIQTLVEVLRAN--PGRDLLELLTEVNRRVCEQEVL 406
           AD L   +     V+YR+  +G+ +IQ+L + LR     G D+L +LTEVN  V  ++  
Sbjct: 382 ADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKD-- 439

Query: 407 GPDCDELRKACLEIRSSLRRRL 428
             D   + K   +   +LR++L
Sbjct: 440 --DKKNMGKQMPQPTFTLRKKL 459


>gi|15718708 caspase 8 isoform C precursor [Homo sapiens]
          Length = 464

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 76/262 (29%), Positives = 118/262 (45%), Gaps = 37/262 (14%)

Query: 175 YDLSKARAAL-LLAVIQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFRE 233
           ++ +KAR  +  L  I+ R G   D  AL      L FE     D T +   E L  + +
Sbjct: 227 HNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIY-Q 285

Query: 234 QLDTCRGPVSCALVALMAHGGPRGQLLGADGQEVQPEALMQELS--RCQVLQGRPKIFLL 291
            +D     + C +  +++HG  +G + G DGQE     L  + +  +C  L G+PK+F +
Sbjct: 286 LMD--HSNMDCFICCILSHGD-KGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFI 342

Query: 292 QACRGGNRDAGVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSS--CRGTPPGSSDQ 349
           QAC+G N   G+              P    S     Q Y E   SS   R  P    D+
Sbjct: 343 QACQGDNYQKGI--------------PVETDSEE---QPYLEMDLSSPQTRYIP----DE 381

Query: 350 ADILTVYSAAEGYVAYRDD-KGSDFIQTLVEVLRAN--PGRDLLELLTEVNRRVCEQEVL 406
           AD L   +     V+YR+  +G+ +IQ+L + LR     G D+L +LTEVN  V  ++  
Sbjct: 382 ADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKD-- 439

Query: 407 GPDCDELRKACLEIRSSLRRRL 428
             D   + K   +   +LR++L
Sbjct: 440 --DKKNMGKQMPQPTFTLRKKL 459


>gi|15718706 caspase 8 isoform B precursor [Homo sapiens]
          Length = 479

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 76/262 (29%), Positives = 118/262 (45%), Gaps = 37/262 (14%)

Query: 175 YDLSKARAAL-LLAVIQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFRE 233
           ++ +KAR  +  L  I+ R G   D  AL      L FE     D T +   E L  + +
Sbjct: 242 HNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIY-Q 300

Query: 234 QLDTCRGPVSCALVALMAHGGPRGQLLGADGQEVQPEALMQELS--RCQVLQGRPKIFLL 291
            +D     + C +  +++HG  +G + G DGQE     L  + +  +C  L G+PK+F +
Sbjct: 301 LMD--HSNMDCFICCILSHGD-KGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFI 357

Query: 292 QACRGGNRDAGVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSS--CRGTPPGSSDQ 349
           QAC+G N   G+              P    S     Q Y E   SS   R  P    D+
Sbjct: 358 QACQGDNYQKGI--------------PVETDSEE---QPYLEMDLSSPQTRYIP----DE 396

Query: 350 ADILTVYSAAEGYVAYRDD-KGSDFIQTLVEVLRAN--PGRDLLELLTEVNRRVCEQEVL 406
           AD L   +     V+YR+  +G+ +IQ+L + LR     G D+L +LTEVN  V  ++  
Sbjct: 397 ADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKD-- 454

Query: 407 GPDCDELRKACLEIRSSLRRRL 428
             D   + K   +   +LR++L
Sbjct: 455 --DKKNMGKQMPQPTFTLRKKL 474


>gi|15718704 caspase 8 isoform A precursor [Homo sapiens]
          Length = 496

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 76/262 (29%), Positives = 118/262 (45%), Gaps = 37/262 (14%)

Query: 175 YDLSKARAAL-LLAVIQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFRE 233
           ++ +KAR  +  L  I+ R G   D  AL      L FE     D T +   E L  + +
Sbjct: 259 HNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIY-Q 317

Query: 234 QLDTCRGPVSCALVALMAHGGPRGQLLGADGQEVQPEALMQELS--RCQVLQGRPKIFLL 291
            +D     + C +  +++HG  +G + G DGQE     L  + +  +C  L G+PK+F +
Sbjct: 318 LMD--HSNMDCFICCILSHGD-KGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFI 374

Query: 292 QACRGGNRDAGVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSS--CRGTPPGSSDQ 349
           QAC+G N   G+              P    S     Q Y E   SS   R  P    D+
Sbjct: 375 QACQGDNYQKGI--------------PVETDSEE---QPYLEMDLSSPQTRYIP----DE 413

Query: 350 ADILTVYSAAEGYVAYRDD-KGSDFIQTLVEVLRAN--PGRDLLELLTEVNRRVCEQEVL 406
           AD L   +     V+YR+  +G+ +IQ+L + LR     G D+L +LTEVN  V  ++  
Sbjct: 414 ADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKD-- 471

Query: 407 GPDCDELRKACLEIRSSLRRRL 428
             D   + K   +   +LR++L
Sbjct: 472 --DKKNMGKQMPQPTFTLRKKL 491


>gi|14916483 caspase 6 isoform alpha preproprotein [Homo sapiens]
          Length = 293

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 62/202 (30%), Positives = 92/202 (45%), Gaps = 26/202 (12%)

Query: 209 LGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVALMAHGGPRGQLLGADGQEVQ 268
           LGFE     D  A+   E L +  E          C +   ++HG   G  + A   +++
Sbjct: 81  LGFEVKCFNDLKAE---ELLLKIHEVSTVSHADADCFVCVFLSHG--EGNHIYAYDAKIE 135

Query: 269 PEAL--MQELSRCQVLQGRPKIFLLQACRGGNRDAGVGPTALPWYWSWLRAPPSVPSHAD 326
            + L  + +  +C  L G+PKIF++QACRG   D  V P  +            V +  +
Sbjct: 136 IQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHDVPVIPLDV------------VDNQTE 183

Query: 327 VLQI-YAEAQGSSCRGTPPGSSDQADILTVYSAAEGYVAYRDD-KGSDFIQTLVEVL-RA 383
            L     E   +S    P G    AD L  YS AEGY ++R+   GS +IQ L E+L + 
Sbjct: 184 KLDTNITEVDAASVYTLPAG----ADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKY 239

Query: 384 NPGRDLLELLTEVNRRVCEQEV 405
               +  ELLT VNR+V ++ V
Sbjct: 240 GSSLEFTELLTLVNRKVSQRRV 261


>gi|14790124 caspase 9 isoform alpha preproprotein [Homo sapiens]
          Length = 416

 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 62/224 (27%), Positives = 97/224 (43%), Gaps = 21/224 (9%)

Query: 189 IQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVA 248
           ++ R G+  D E L     +L F   V+ D TA+     L +  +Q     G + C +V 
Sbjct: 177 LRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQ---DHGALDCCVVV 233

Query: 249 LMAHGGPR------GQLLGADGQEVQPEALMQELS--RCQVLQGRPKIFLLQACRGGNRD 300
           +++HG         G + G DG  V  E ++   +   C  L G+PK+F +QAC G  +D
Sbjct: 234 ILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKD 293

Query: 301 AG--VGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSA 358
            G  V  T+           P      + L+ + +    S   TP      +DI   YS 
Sbjct: 294 HGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTP------SDIFVSYST 347

Query: 359 AEGYVAYRDDK-GSDFIQTLVEVLRA-NPGRDLLELLTEVNRRV 400
             G+V++RD K GS +++TL ++        DL  LL  V   V
Sbjct: 348 FPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAV 391


>gi|14916485 caspase 6 isoform beta [Homo sapiens]
          Length = 204

 Score = 65.5 bits (158), Expect = 9e-11
 Identities = 53/167 (31%), Positives = 81/167 (48%), Gaps = 23/167 (13%)

Query: 244 CALVALMAHGGPRGQLLGADGQEVQPEAL--MQELSRCQVLQGRPKIFLLQACRGGNRDA 301
           C +   ++HG   G  + A   +++ + L  + +  +C  L G+PKIF++QACRG   D 
Sbjct: 24  CFVCVFLSHG--EGNHIYAYDAKIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHDV 81

Query: 302 GVGPTALPWYWSWLRAPPSVPSHADVLQI-YAEAQGSSCRGTPPGSSDQADILTVYSAAE 360
            V P  +            V +  + L     E   +S    P G    AD L  YS AE
Sbjct: 82  PVIPLDV------------VDNQTEKLDTNITEVDAASVYTLPAG----ADFLMCYSVAE 125

Query: 361 GYVAYRDD-KGSDFIQTLVEVL-RANPGRDLLELLTEVNRRVCEQEV 405
           GY ++R+   GS +IQ L E+L +     +  ELLT VNR+V ++ V
Sbjct: 126 GYYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLVNRKVSQRRV 172


>gi|15718698 caspase 7 isoform delta [Homo sapiens]
          Length = 336

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 60/213 (28%), Positives = 91/213 (42%), Gaps = 34/213 (15%)

Query: 192 RPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVALMA 251
           R G   D EAL     +LGF+  V  D +    Q+ L +  E+  T     +C    L++
Sbjct: 120 RNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHT---NAACFACILLS 176

Query: 252 HGGPRGQLLGADG-QEVQPEALMQELSRCQVLQGRPKIFLLQACRGGNRDAGVGPTALPW 310
           HG     + G DG   ++         RC+ L  +PK+F +QACRG   D G+   + P 
Sbjct: 177 HG-EENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPI 235

Query: 311 YWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAEGYVAYRD-DK 369
             +       +P                          +AD L  YS   GY ++R   +
Sbjct: 236 NDTDANPRYKIPV-------------------------EADFLFAYSTVPGYYSWRSPGR 270

Query: 370 GSDFIQTLVEVLRANPGRDL--LELLTEVNRRV 400
           GS F+Q L  +L  + G+DL  +++LT VN RV
Sbjct: 271 GSWFVQALCSILEEH-GKDLEIMQILTRVNDRV 302


>gi|15718700 caspase 7 isoform alpha [Homo sapiens]
          Length = 303

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 60/213 (28%), Positives = 91/213 (42%), Gaps = 34/213 (15%)

Query: 192 RPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVALMA 251
           R G   D EAL     +LGF+  V  D +    Q+ L +  E+  T     +C    L++
Sbjct: 87  RNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHT---NAACFACILLS 143

Query: 252 HGGPRGQLLGADG-QEVQPEALMQELSRCQVLQGRPKIFLLQACRGGNRDAGVGPTALPW 310
           HG     + G DG   ++         RC+ L  +PK+F +QACRG   D G+   + P 
Sbjct: 144 HG-EENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPI 202

Query: 311 YWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAEGYVAYRD-DK 369
             +       +P                          +AD L  YS   GY ++R   +
Sbjct: 203 NDTDANPRYKIPV-------------------------EADFLFAYSTVPGYYSWRSPGR 237

Query: 370 GSDFIQTLVEVLRANPGRDL--LELLTEVNRRV 400
           GS F+Q L  +L  + G+DL  +++LT VN RV
Sbjct: 238 GSWFVQALCSILEEH-GKDLEIMQILTRVNDRV 269


>gi|4502581 caspase 7 isoform alpha precursor [Homo sapiens]
          Length = 303

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 60/213 (28%), Positives = 91/213 (42%), Gaps = 34/213 (15%)

Query: 192 RPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVALMA 251
           R G   D EAL     +LGF+  V  D +    Q+ L +  E+  T     +C    L++
Sbjct: 87  RNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHT---NAACFACILLS 143

Query: 252 HGGPRGQLLGADG-QEVQPEALMQELSRCQVLQGRPKIFLLQACRGGNRDAGVGPTALPW 310
           HG     + G DG   ++         RC+ L  +PK+F +QACRG   D G+   + P 
Sbjct: 144 HG-EENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPI 202

Query: 311 YWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAEGYVAYRD-DK 369
             +       +P                          +AD L  YS   GY ++R   +
Sbjct: 203 NDTDANPRYKIPV-------------------------EADFLFAYSTVPGYYSWRSPGR 237

Query: 370 GSDFIQTLVEVLRANPGRDL--LELLTEVNRRV 400
           GS F+Q L  +L  + G+DL  +++LT VN RV
Sbjct: 238 GSWFVQALCSILEEH-GKDLEIMQILTRVNDRV 269


>gi|14790115 caspase 3 preproprotein [Homo sapiens]
          Length = 277

 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 57/215 (26%), Positives = 91/215 (42%), Gaps = 35/215 (16%)

Query: 192 RPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVALMA 251
           R G   D   L      L +E   + D T +   E +    ++  + R    C L++   
Sbjct: 64  RSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS--- 120

Query: 252 HGGPRGQLLGADGQ-EVQPEALMQELSRCQVLQGRPKIFLLQACRGGNRDAGVGPTALPW 310
             G  G + G +G  +++         RC+ L G+PK+F++QACRG   D G+       
Sbjct: 121 -HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGI------- 172

Query: 311 YWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAEGYVAYRDDK- 369
                       S  D           +C   P     +AD L  YS A GY ++R+ K 
Sbjct: 173 ---------ETDSGVD--------DDMACHKIPV----EADFLYAYSTAPGYYSWRNSKD 211

Query: 370 GSDFIQTLVEVLRANPGR-DLLELLTEVNRRVCEQ 403
           GS FIQ+L  +L+    + + + +LT VNR+V  +
Sbjct: 212 GSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATE 246


>gi|14790119 caspase 3 preproprotein [Homo sapiens]
          Length = 277

 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 57/215 (26%), Positives = 91/215 (42%), Gaps = 35/215 (16%)

Query: 192 RPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVALMA 251
           R G   D   L      L +E   + D T +   E +    ++  + R    C L++   
Sbjct: 64  RSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS--- 120

Query: 252 HGGPRGQLLGADGQ-EVQPEALMQELSRCQVLQGRPKIFLLQACRGGNRDAGVGPTALPW 310
             G  G + G +G  +++         RC+ L G+PK+F++QACRG   D G+       
Sbjct: 121 -HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGI------- 172

Query: 311 YWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAEGYVAYRDDK- 369
                       S  D           +C   P     +AD L  YS A GY ++R+ K 
Sbjct: 173 ---------ETDSGVD--------DDMACHKIPV----EADFLYAYSTAPGYYSWRNSKD 211

Query: 370 GSDFIQTLVEVLRANPGR-DLLELLTEVNRRVCEQ 403
           GS FIQ+L  +L+    + + + +LT VNR+V  +
Sbjct: 212 GSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATE 246


>gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens]
          Length = 522

 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 58/224 (25%), Positives = 97/224 (43%), Gaps = 35/224 (15%)

Query: 189 IQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVA 248
           ++ R G   D E L  +   LGF   +  + T    + E+   +++ +       C +  
Sbjct: 297 LKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTK--VEMEMVLQKQKCNPAHADGDCFVFC 354

Query: 249 LMAHGGPRGQLLGADGQEVQPEALMQELS--RCQVLQGRPKIFLLQACRGGNRDAGVGPT 306
           ++ HG   G +  +D   +    +M   +  +C  L  +PK+F +QAC+G          
Sbjct: 355 ILTHGR-FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGE--------- 404

Query: 307 ALPWYWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAEGYVAYR 366
                       PSV   AD L    E   +S + + P    +AD L   +   GYV++R
Sbjct: 405 ---------EIQPSVSIEADALN--PEQAPTSLQDSIPA---EADFLLGLATVPGYVSFR 450

Query: 367 D-DKGSDFIQTLVEVLRANPGR--DLLELLTEVN----RRVCEQ 403
             ++GS +IQ+L   L+    R  D+L +LT VN    RRV +Q
Sbjct: 451 HVEEGSWYIQSLCNHLKKLVPRHEDILSILTAVNDDVSRRVDKQ 494


>gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens]
          Length = 479

 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 58/224 (25%), Positives = 97/224 (43%), Gaps = 35/224 (15%)

Query: 189 IQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVA 248
           ++ R G   D E L  +   LGF   +  + T    + E+   +++ +       C +  
Sbjct: 254 LKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTK--VEMEMVLQKQKCNPAHADGDCFVFC 311

Query: 249 LMAHGGPRGQLLGADGQEVQPEALMQELS--RCQVLQGRPKIFLLQACRGGNRDAGVGPT 306
           ++ HG   G +  +D   +    +M   +  +C  L  +PK+F +QAC+G          
Sbjct: 312 ILTHGR-FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGE--------- 361

Query: 307 ALPWYWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAEGYVAYR 366
                       PSV   AD L    E   +S + + P    +AD L   +   GYV++R
Sbjct: 362 ---------EIQPSVSIEADALN--PEQAPTSLQDSIPA---EADFLLGLATVPGYVSFR 407

Query: 367 D-DKGSDFIQTLVEVLRANPGR--DLLELLTEVN----RRVCEQ 403
             ++GS +IQ+L   L+    R  D+L +LT VN    RRV +Q
Sbjct: 408 HVEEGSWYIQSLCNHLKKLVPRHEDILSILTAVNDDVSRRVDKQ 451


>gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens]
          Length = 521

 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 53/216 (24%), Positives = 90/216 (41%), Gaps = 31/216 (14%)

Query: 189 IQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVA 248
           ++ R G   D E L  +   LGF   +  + T    + E+   +++ +       C +  
Sbjct: 297 LKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTK--VEMEMVLQKQKCNPAHADGDCFVFC 354

Query: 249 LMAHGGPRGQLLGADGQEVQPEALMQELS--RCQVLQGRPKIFLLQACRGGNRDAGVGPT 306
           ++ HG   G +  +D   +    +M   +  +C  L  +PK+F +QAC+G          
Sbjct: 355 ILTHGR-FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGE--------- 404

Query: 307 ALPWYWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAEGYVAYR 366
                       PSV   AD L    E   +S + + P    +AD L   +   GYV++R
Sbjct: 405 ---------EIQPSVSIEADALN--PEQAPTSLQDSIPA---EADFLLGLATVPGYVSFR 450

Query: 367 D-DKGSDFIQTLVEVLRANPGRDL--LELLTEVNRR 399
             ++GS +IQ+L   L+    R L  LE   E+  R
Sbjct: 451 HVEEGSWYIQSLCNHLKKLVPRMLKFLEKTMEIRGR 486


>gi|15431332 caspase 1 isoform delta [Homo sapiens]
          Length = 263

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 15/133 (11%)

Query: 178 SKARAALLLA-----VIQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFR 232
           S+ R AL++       I  R GA+ D+  +  L   LG+   V+ + TA     EL  F 
Sbjct: 67  SRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFA 126

Query: 233 EQLDTCRGPVSCALVALMAHGGPRGQLLGADGQEVQPEAL-------MQELSRCQVLQGR 285
            + +          +  M+HG   G + G    E  P+ L       M     C  L+ +
Sbjct: 127 HRPE--HKTSDSTFLVFMSHGIREG-ICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDK 183

Query: 286 PKIFLLQACRGGN 298
           PK+ ++QACRG N
Sbjct: 184 PKVIIIQACRGDN 196


>gi|15431330 caspase 1 isoform gamma precursor [Homo sapiens]
          Length = 311

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 36/131 (27%), Positives = 56/131 (42%), Gaps = 15/131 (11%)

Query: 178 SKARAALLLA-----VIQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFR 232
           S+ R AL++       I  R GA+ D+  +  L   LG+   V+ + TA     EL  F 
Sbjct: 67  SRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFA 126

Query: 233 EQLDTCRGPVSCALVALMAHGGPRGQLLGADGQEVQPEAL-------MQELSRCQVLQGR 285
            + +          +  M+HG   G + G    E  P+ L       M     C  L+ +
Sbjct: 127 HRPE--HKTSDSTFLVFMSHGIREG-ICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDK 183

Query: 286 PKIFLLQACRG 296
           PK+ ++QACRG
Sbjct: 184 PKVIIIQACRG 194


>gi|15431328 caspase 1 isoform alpha precursor [Homo sapiens]
          Length = 404

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 36/131 (27%), Positives = 56/131 (42%), Gaps = 15/131 (11%)

Query: 178 SKARAALLLA-----VIQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFR 232
           S+ R AL++       I  R GA+ D+  +  L   LG+   V+ + TA     EL  F 
Sbjct: 160 SRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFA 219

Query: 233 EQLDTCRGPVSCALVALMAHGGPRGQLLGADGQEVQPEAL-------MQELSRCQVLQGR 285
            + +          +  M+HG   G + G    E  P+ L       M     C  L+ +
Sbjct: 220 HRPE--HKTSDSTFLVFMSHGIREG-ICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDK 276

Query: 286 PKIFLLQACRG 296
           PK+ ++QACRG
Sbjct: 277 PKVIIIQACRG 287


>gi|4502573 caspase 1 isoform beta precursor [Homo sapiens]
          Length = 383

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 36/131 (27%), Positives = 56/131 (42%), Gaps = 15/131 (11%)

Query: 178 SKARAALLLA-----VIQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFR 232
           S+ R AL++       I  R GA+ D+  +  L   LG+   V+ + TA     EL  F 
Sbjct: 139 SRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFA 198

Query: 233 EQLDTCRGPVSCALVALMAHGGPRGQLLGADGQEVQPEAL-------MQELSRCQVLQGR 285
            + +          +  M+HG   G + G    E  P+ L       M     C  L+ +
Sbjct: 199 HRPE--HKTSDSTFLVFMSHGIREG-ICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDK 255

Query: 286 PKIFLLQACRG 296
           PK+ ++QACRG
Sbjct: 256 PKVIIIQACRG 266


>gi|15451910 caspase 4 isoform gamma precursor [Homo sapiens]
          Length = 321

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 10/115 (8%)

Query: 192 RPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVALMA 251
           R GA  D+  +  L   L +   V  + TA+  +  L  F  + +          + LM+
Sbjct: 96  RNGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPE--HKSSDSTFLVLMS 153

Query: 252 HGGPRGQLLGADGQEVQPEALMQEL-------SRCQVLQGRPKIFLLQACRGGNR 299
           HG   G + G    E +P+ L+ +          C  L+ +PK+ ++QACRG NR
Sbjct: 154 HGILEG-ICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANR 207


>gi|4502577 caspase 4 isoform alpha precursor [Homo sapiens]
          Length = 377

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 10/115 (8%)

Query: 192 RPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVALMA 251
           R GA  D+  +  L   L +   V  + TA+  +  L  F  + +          + LM+
Sbjct: 152 RNGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPE--HKSSDSTFLVLMS 209

Query: 252 HGGPRGQLLGADGQEVQPEALMQEL-------SRCQVLQGRPKIFLLQACRGGNR 299
           HG   G + G    E +P+ L+ +          C  L+ +PK+ ++QACRG NR
Sbjct: 210 HGILEG-ICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANR 263


>gi|209870079 caspase 5 isoform f precursor [Homo sapiens]
          Length = 447

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 43/198 (21%), Positives = 82/198 (41%), Gaps = 27/198 (13%)

Query: 189 IQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVA 248
           +  R GA +D+  +  L   LG+      + TA+  +  L  F  + +          + 
Sbjct: 219 LPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPE--HKSSDSTFLV 276

Query: 249 LMAHGGPRGQLLGADGQEVQPEALMQEL-------SRCQVLQGRPKIFLLQACRGGNRDA 301
           LM+HG   G + G   ++ +P+ L+ +          C  L+ +PK+ ++QACRG     
Sbjct: 277 LMSHGILEG-ICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGE 335

Query: 302 GVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAEG 361
                       W+R  P     A +  I +++  +    +     ++ D +   S+   
Sbjct: 336 -----------LWVRDSP-----ASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPH 379

Query: 362 YVAYRD-DKGSDFIQTLV 378
            V++RD  +GS FI  L+
Sbjct: 380 NVSWRDRTRGSIFITELI 397


>gi|209870073 caspase 5 isoform c [Homo sapiens]
          Length = 292

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 43/198 (21%), Positives = 82/198 (41%), Gaps = 27/198 (13%)

Query: 189 IQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVA 248
           +  R GA +D+  +  L   LG+      + TA+  +  L  F  + +          + 
Sbjct: 64  LPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPE--HKSSDSTFLV 121

Query: 249 LMAHGGPRGQLLGADGQEVQPEALMQEL-------SRCQVLQGRPKIFLLQACRGGNRDA 301
           LM+HG   G + G   ++ +P+ L+ +          C  L+ +PK+ ++QACRG     
Sbjct: 122 LMSHGILEG-ICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGE 180

Query: 302 GVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAEG 361
                       W+R  P     A +  I +++  +    +     ++ D +   S+   
Sbjct: 181 -----------LWVRDSP-----ASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPH 224

Query: 362 YVAYRD-DKGSDFIQTLV 378
            V++RD  +GS FI  L+
Sbjct: 225 NVSWRDRTRGSIFITELI 242


>gi|209870071 caspase 5 isoform b precursor [Homo sapiens]
          Length = 376

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 43/198 (21%), Positives = 82/198 (41%), Gaps = 27/198 (13%)

Query: 189 IQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVA 248
           +  R GA +D+  +  L   LG+      + TA+  +  L  F  + +          + 
Sbjct: 148 LPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPE--HKSSDSTFLV 205

Query: 249 LMAHGGPRGQLLGADGQEVQPEALMQEL-------SRCQVLQGRPKIFLLQACRGGNRDA 301
           LM+HG   G + G   ++ +P+ L+ +          C  L+ +PK+ ++QACRG     
Sbjct: 206 LMSHGILEG-ICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGE 264

Query: 302 GVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAEG 361
                       W+R  P     A +  I +++  +    +     ++ D +   S+   
Sbjct: 265 -----------LWVRDSP-----ASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPH 308

Query: 362 YVAYRD-DKGSDFIQTLV 378
            V++RD  +GS FI  L+
Sbjct: 309 NVSWRDRTRGSIFITELI 326


>gi|209870069 caspase 5 isoform a precursor [Homo sapiens]
          Length = 434

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 43/198 (21%), Positives = 82/198 (41%), Gaps = 27/198 (13%)

Query: 189 IQGRPGAQHDVEALGGLCWALGFETTVRTDPTAQAFQEELAQFREQLDTCRGPVSCALVA 248
           +  R GA +D+  +  L   LG+      + TA+  +  L  F  + +          + 
Sbjct: 206 LPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPE--HKSSDSTFLV 263

Query: 249 LMAHGGPRGQLLGADGQEVQPEALMQEL-------SRCQVLQGRPKIFLLQACRGGNRDA 301
           LM+HG   G + G   ++ +P+ L+ +          C  L+ +PK+ ++QACRG     
Sbjct: 264 LMSHGILEG-ICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGE 322

Query: 302 GVGPTALPWYWSWLRAPPSVPSHADVLQIYAEAQGSSCRGTPPGSSDQADILTVYSAAEG 361
                       W+R  P     A +  I +++  +    +     ++ D +   S+   
Sbjct: 323 -----------LWVRDSP-----ASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPH 366

Query: 362 YVAYRD-DKGSDFIQTLV 378
            V++RD  +GS FI  L+
Sbjct: 367 NVSWRDRTRGSIFITELI 384


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,198,552
Number of Sequences: 37866
Number of extensions: 1092658
Number of successful extensions: 4745
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 4194
Number of HSP's gapped (non-prelim): 567
length of query: 432
length of database: 18,247,518
effective HSP length: 105
effective length of query: 327
effective length of database: 14,271,588
effective search space: 4666809276
effective search space used: 4666809276
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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