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Search of human proteins with 239755920
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239755920 PREDICTED: hypothetical protein XP_002344746 [Homo
sapiens]
(600 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239755920 PREDICTED: hypothetical protein XP_002344746 [Homo ... 1236 0.0
gi|239744740 PREDICTED: hypothetical protein XP_002343259 [Homo ... 927 0.0
gi|239750438 PREDICTED: hypothetical protein [Homo sapiens] 768 0.0
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 54 4e-07
gi|57864582 hornerin [Homo sapiens] 52 1e-06
gi|169171347 PREDICTED: hypothetical protein [Homo sapiens] 52 2e-06
gi|169172209 PREDICTED: hypothetical protein [Homo sapiens] 52 2e-06
gi|169170953 PREDICTED: hypothetical protein [Homo sapiens] 52 2e-06
gi|239508753 PREDICTED: hypothetical protein [Homo sapiens] 52 2e-06
gi|62122917 filaggrin family member 2 [Homo sapiens] 52 2e-06
gi|239750846 PREDICTED: hypothetical protein [Homo sapiens] 50 6e-06
gi|239750574 PREDICTED: hypothetical protein [Homo sapiens] 50 6e-06
gi|239745208 PREDICTED: hypothetical protein XP_002343389 [Homo ... 50 6e-06
gi|169205732 PREDICTED: hypothetical protein [Homo sapiens] 50 6e-06
gi|239756319 PREDICTED: hypothetical protein [Homo sapiens] 50 8e-06
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s... 49 1e-05
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s... 49 1e-05
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s... 49 1e-05
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap... 49 1e-05
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 49 1e-05
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 49 1e-05
gi|56699482 hypothetical protein LOC25940 [Homo sapiens] 49 2e-05
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 48 3e-05
gi|28875797 small protein rich in arginine and glycine [Homo sap... 47 4e-05
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 47 7e-05
gi|239749709 PREDICTED: hypothetical protein [Homo sapiens] 47 7e-05
gi|60097902 filaggrin [Homo sapiens] 45 1e-04
gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 45 2e-04
gi|186928825 dermokine isoform 3 precursor [Homo sapiens] 45 2e-04
gi|156616290 collagen type VI alpha 6 [Homo sapiens] 45 2e-04
>gi|239755920 PREDICTED: hypothetical protein XP_002344746 [Homo
sapiens]
Length = 600
Score = 1236 bits (3197), Expect = 0.0
Identities = 600/600 (100%), Positives = 600/600 (100%)
Query: 1 MAFVLVDAASCGDLDAFVDETDRWHSKPRKKAKAPALSGLWGGRSHHKACGEIATGARGA 60
MAFVLVDAASCGDLDAFVDETDRWHSKPRKKAKAPALSGLWGGRSHHKACGEIATGARGA
Sbjct: 1 MAFVLVDAASCGDLDAFVDETDRWHSKPRKKAKAPALSGLWGGRSHHKACGEIATGARGA 60
Query: 61 DTARCRWIQSCPLQAVAAAQKERALEISQSSGEPQPQRSPGPVSAQALPPPQRTPTLPPP 120
DTARCRWIQSCPLQAVAAAQKERALEISQSSGEPQPQRSPGPVSAQALPPPQRTPTLPPP
Sbjct: 61 DTARCRWIQSCPLQAVAAAQKERALEISQSSGEPQPQRSPGPVSAQALPPPQRTPTLPPP 120
Query: 121 ATPHQHTLVVCLPSHPRRHRRGGWLLPSQARSDCWGILLAFSPSQTHWCKKVFSTWIRQI 180
ATPHQHTLVVCLPSHPRRHRRGGWLLPSQARSDCWGILLAFSPSQTHWCKKVFSTWIRQI
Sbjct: 121 ATPHQHTLVVCLPSHPRRHRRGGWLLPSQARSDCWGILLAFSPSQTHWCKKVFSTWIRQI 180
Query: 181 DVKTEGELKTKNIRTCRAYFWSDSDVSGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRL 240
DVKTEGELKTKNIRTCRAYFWSDSDVSGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRL
Sbjct: 181 DVKTEGELKTKNIRTCRAYFWSDSDVSGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRL 240
Query: 241 FLRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQ 300
FLRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQ
Sbjct: 241 FLRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQ 300
Query: 301 TAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG 360
TAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG
Sbjct: 301 TAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG 360
Query: 361 HGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGR 420
HGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGR
Sbjct: 361 HGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGR 420
Query: 421 HAGEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLA 480
HAGEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLA
Sbjct: 421 HAGEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLA 480
Query: 481 RERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQ 540
RERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQ
Sbjct: 481 RERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQ 540
Query: 541 LIHDRLGQGARQRERRRAVGRQRQRGEERRLVTQHRAHGEVRRPKREERAGSRLAPEPCR 600
LIHDRLGQGARQRERRRAVGRQRQRGEERRLVTQHRAHGEVRRPKREERAGSRLAPEPCR
Sbjct: 541 LIHDRLGQGARQRERRRAVGRQRQRGEERRLVTQHRAHGEVRRPKREERAGSRLAPEPCR 600
>gi|239744740 PREDICTED: hypothetical protein XP_002343259 [Homo
sapiens]
Length = 457
Score = 927 bits (2395), Expect = 0.0
Identities = 453/453 (100%), Positives = 453/453 (100%)
Query: 148 SQARSDCWGILLAFSPSQTHWCKKVFSTWIRQIDVKTEGELKTKNIRTCRAYFWSDSDVS 207
SQARSDCWGILLAFSPSQTHWCKKVFSTWIRQIDVKTEGELKTKNIRTCRAYFWSDSDVS
Sbjct: 5 SQARSDCWGILLAFSPSQTHWCKKVFSTWIRQIDVKTEGELKTKNIRTCRAYFWSDSDVS 64
Query: 208 GTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFRAR 267
GTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFRAR
Sbjct: 65 GTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFRAR 124
Query: 268 VHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEE 327
VHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEE
Sbjct: 125 VHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEE 184
Query: 328 GVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 387
GVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL
Sbjct: 185 GVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 244
Query: 388 RRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLAR 447
RRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLAR
Sbjct: 245 RRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLAR 304
Query: 448 QARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQA 507
QARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQA
Sbjct: 305 QARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQA 364
Query: 508 ASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERRRAVGRQRQRGE 567
ASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERRRAVGRQRQRGE
Sbjct: 365 ASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERRRAVGRQRQRGE 424
Query: 568 ERRLVTQHRAHGEVRRPKREERAGSRLAPEPCR 600
ERRLVTQHRAHGEVRRPKREERAGSRLAPEPCR
Sbjct: 425 ERRLVTQHRAHGEVRRPKREERAGSRLAPEPCR 457
>gi|239750438 PREDICTED: hypothetical protein [Homo sapiens]
Length = 510
Score = 768 bits (1982), Expect = 0.0
Identities = 404/506 (79%), Positives = 409/506 (80%), Gaps = 67/506 (13%)
Query: 148 SQARSDCWGILLAFSPSQTHWCKKVFSTWIRQIDVKTEGELKTKNIRTCRAYFWSDSDVS 207
SQARSDCWGILLAFSPSQTHWCKKVFSTWIRQIDVKTEGELKTKNIRTCRAYFWSDSDVS
Sbjct: 5 SQARSDCWGILLAFSPSQTHWCKKVFSTWIRQIDVKTEGELKTKNIRTCRAYFWSDSDVS 64
Query: 208 GTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFRAR 267
GTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFRAR
Sbjct: 65 GTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFRAR 124
Query: 268 VHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEE 327
VHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEE
Sbjct: 125 VHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEE 184
Query: 328 GVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 387
GVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL
Sbjct: 185 GVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 244
Query: 388 RRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLAR 447
RRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLAR
Sbjct: 245 RRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLAR 304
Query: 448 QARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQA 507
QARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQA
Sbjct: 305 QARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQA 364
Query: 508 ASAGRDGGGAMAP--QMRLGPQ---------GGERDAGLGRP------------------ 538
ASAGRDGGGAMA R G E+ GR
Sbjct: 365 ASAGRDGGGAMASGIYQRAGIAIEHKPGCLCSTEKFCLFGREPRMQTKCKTHADAQFFSL 424
Query: 539 --------------HQLIHDRLGQGARQRERRRAVGRQRQ----------RGEERR---- 570
H L ++ G + ER +GR Q R ERR
Sbjct: 425 QVHLGVVLHLFFGLHGLQRPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERRRAVG 484
Query: 571 ----------LVTQHRAHGEVRRPKR 586
LVTQHRAHGEVRRP R
Sbjct: 485 RQRQRGEERRLVTQHRAHGEVRRPVR 510
>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
Length = 819
Score = 53.9 bits (128), Expect = 4e-07
Identities = 104/423 (24%), Positives = 157/423 (37%), Gaps = 58/423 (13%)
Query: 213 GRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFRARVHCHR 272
GRA LG A P++ + A G + G+G ++ +A +
Sbjct: 14 GRAGPGAPLGAALARTPVELAAESAAPALSAAAAGVKILGSGDKK---LRRQKAAAGGKK 70
Query: 273 GRAGGQGGDFAVQGPRGRRH-------GG---QGGGEQTAAVRDRHRDGVGAVAQPRAHG 322
R GQ G AV G R+H GG +GGGEQ AA G G +PR G
Sbjct: 71 ARLRGQKG--AVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLG-GRGRKPRRRG 127
Query: 323 VQIEE-GVAVHR--------AGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLE 373
+ G R AG RG G + GV+ Q E+ A
Sbjct: 128 QKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAA--------- 178
Query: 374 VEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRN-RGQEGTHASGRHAGEGAPHGKLA 432
G + R G+ RR G RG + D G R + + G GR P
Sbjct: 179 --AAGAKSRSGKKPRRRG-AKSRGDE--DKKGRQREAKSRFGKTRGGRRKKHRRPKPAAG 233
Query: 433 GVQEERVPVEELLARQARGEAEARQG--ALGQVR-GGRVRLHRERREGLLARERAR-LFH 488
G + R ++ ++ RG+ A G +G+ R GG +L R+ + LA + R
Sbjct: 234 GAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAAT 293
Query: 489 LGRRCAL---ANRAPALLRAQAASAGRDG----------GGAMAPQMRLGPQGGERDAGL 535
G + A R P L Q GR G A A + G G ++ A +
Sbjct: 294 AGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVV 353
Query: 536 GRPHQLIHDRLGQGARQRERRRAVGRQRQRGEERRLVTQHRAHGEVRRPKREERAGSRLA 595
G + R G+ R R++ A G + + G +++ + + + G+ R+ R + R
Sbjct: 354 GVKSRKKQRRRGKKPR-RQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQ 412
Query: 596 PEP 598
P
Sbjct: 413 KAP 415
Score = 45.1 bits (105), Expect = 2e-04
Identities = 88/369 (23%), Positives = 133/369 (36%), Gaps = 67/369 (18%)
Query: 252 GAGGERGGAAVEFRARVHCHRGRAGGQ--------GGDFAV--QGPRG-----RRHGGQG 296
GA RGG + R + GG+ GGD + QG +R G
Sbjct: 234 GAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAAT 293
Query: 297 GGEQTAAVRDRHRDGVGAVA-------------QPRAHGVQIEEGVAVHRAGGCRRGGGR 343
GE+ AA + R G G + +PR G + + A G +RGGG
Sbjct: 294 AGEKPAA---KGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAA----GTKRGGGG 346
Query: 344 RCGHVRVGVREQASERGHGQ-------------ALGGQDV--LLEVEGQG-GRGRPG-QS 386
+ VGV+ + +R G+ + GG D L E + +G GR +P Q+
Sbjct: 347 QQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQN 406
Query: 387 LRRSGRGHGRGIQARDTGGG---PRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEE 443
RR + + A+ GGG PR RG + + G + G Q+ R E
Sbjct: 407 PRRRAQ---KAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAE 463
Query: 444 LLARQARGEAEARQGALG---QVRGGRVRLHRER---REGLLARERARLFHLGRRCALAN 497
A + + RQ A + RGG ++ H + R G A +
Sbjct: 464 AGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGR 523
Query: 498 RAPALLRAQAASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERRR 557
+ P + A A GG+ + Q + G G G Q R G G + R+ +
Sbjct: 524 KQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQ---SRGGGGNKPRQWGQ 580
Query: 558 AVGRQRQRG 566
+ RG
Sbjct: 581 TAAAAKTRG 589
Score = 40.0 bits (92), Expect = 0.006
Identities = 80/371 (21%), Positives = 131/371 (35%), Gaps = 69/371 (18%)
Query: 252 GAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRD----- 306
G GG++ A V ++R R + + G + R G + G + D
Sbjct: 343 GGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKP 402
Query: 307 -----RHRDGVGAVAQPRAHGVQIEEG----VAVHRAGGCRRGGGRRCGHVRVGVREQAS 357
R R A+PR G + A R G R GGG++ R++A+
Sbjct: 403 RWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAA 462
Query: 358 ERG---HGQALGGQDVL----LEVEGQGGRGRPGQSL-RRSGRGHGRGIQARDTG----- 404
E G G G+ + G G + G++L RR + G +A G
Sbjct: 463 EAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAAGAKSRG 522
Query: 405 ------------------GGPRNRGQEGTHASGR--HAGEGAPHGKLAGVQEERVPVEEL 444
GG ++R ++ A+G H G G + G + R +
Sbjct: 523 RKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRGGGGNKPRQWGQTA 582
Query: 445 LARQARGEAEARQG----ALGQVRG----GRVRLHRERREGLLARERARLFHLGRRCALA 496
A + RG + + G A G + G + R++ G A+ R + + G++ A A
Sbjct: 583 AAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKSRKKPWRRGQKDAAA 642
Query: 497 NRAPALLRAQAASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERR 556
+A A A G G P+ + G + Q AR++ RR
Sbjct: 643 AE-----KAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAE------ARKKPRR 691
Query: 557 RAVGRQRQRGE 567
R R + RG+
Sbjct: 692 R---RAKSRGD 699
Score = 33.9 bits (76), Expect = 0.44
Identities = 53/193 (27%), Positives = 72/193 (37%), Gaps = 45/193 (23%)
Query: 247 GRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRD 306
G G+GG++ A A GQ + A + PR RR +G G Q AAV
Sbjct: 650 GATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAE-ARKKPRRRRAKSRGDGGQNAAV-- 706
Query: 307 RHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALG 366
+ + G + R G R GGG A RG G A
Sbjct: 707 -------GINPWQRRGKK-------PRLGKSRGGGG-------------AKSRGSGGA-- 737
Query: 367 GQDVLLEVEGQGG-RGRPGQSLRRSGRGHGRGIQARDTGGGPRNR-GQEGTHASGRHA-- 422
+ G GG + R G+ S + HG G R GGG ++R G++ A G+ A
Sbjct: 738 ------KSRGSGGAKSRSGKKAAAS-KSHGGGGAKRRRGGGAKSRSGEKAVTAGGQKAAA 790
Query: 423 --GEGAPHGKLAG 433
G+ P K G
Sbjct: 791 AGGKKPPRVKSRG 803
Score = 32.0 bits (71), Expect = 1.7
Identities = 40/157 (25%), Positives = 62/157 (39%), Gaps = 22/157 (14%)
Query: 317 QPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEV-- 374
+P A G + AV + R+ RR +A RG G GQ+ + +
Sbjct: 665 KPAAAGSESSAAAAVGQEAEARKKPRRR----------RAKSRGDG----GQNAAVGINP 710
Query: 375 -EGQGGRGRPGQSLRRSG---RGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGK 430
+ +G + R G+S G RG G G ++R +GG G++ AS H G GA +
Sbjct: 711 WQRRGKKPRLGKSRGGGGAKSRGSG-GAKSRGSGGAKSRSGKKAA-ASKSHGGGGAKRRR 768
Query: 431 LAGVQEERVPVEELLARQARGEAEARQGALGQVRGGR 467
G + Q A ++ + RGGR
Sbjct: 769 GGGAKSRSGEKAVTAGGQKAAAAGGKKPPRVKSRGGR 805
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 52.4 bits (124), Expect = 1e-06
Identities = 77/314 (24%), Positives = 105/314 (33%), Gaps = 64/314 (20%)
Query: 246 FGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVR 305
+GRQG G+G G GQ G + Q P RHG G ++
Sbjct: 2525 YGRQGSGSGQSPG-----------------HGQRGSGSRQSPSYGRHGSGSGRSSSSG-- 2565
Query: 306 DRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG--HGQ 363
+H G+G + H + + + G G G G+ + G R S RG HG
Sbjct: 2566 -QHGSGLGESSGFGHHESSSGQSSSYSQHGS---GSGHSSGYGQHGSRSGQSSRGERHGS 2621
Query: 364 ALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASG-RHA 422
+ G GQ G G R GHGR G G G H SG H+
Sbjct: 2622 SSGSSSHY----GQHGSG------SRQSSGHGR------QGSGSGQSPSRGRHGSGLGHS 2665
Query: 423 GEGAPHGKLAGVQEERVPVEELLARQA-RGEAEARQG---ALGQVRGGRVRLHRERREGL 478
HG +G R P E L + G+ E+ G A Q G + + G
Sbjct: 2666 SSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGS 2725
Query: 479 LARERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMAPQMRLGPQGGERDAGLGRP 538
+ + + G Q++S G G G+ G G G
Sbjct: 2726 TSGQSSTFDQEGSS-----------TGQSSSYGHRGSGS-------SQSSGYGRHGAGSG 2767
Query: 539 HQLIHDRLGQGARQ 552
L H R G G+ Q
Sbjct: 2768 QSLSHGRHGSGSGQ 2781
Score = 49.3 bits (116), Expect = 1e-05
Identities = 77/332 (23%), Positives = 111/332 (33%), Gaps = 57/332 (17%)
Query: 246 FGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVR 305
+GRQG G+G G GQ G + Q P RHG G ++
Sbjct: 1115 YGRQGSGSGQSPG-----------------HGQRGSGSRQSPSYGRHGSGSGRSSSSG-- 1155
Query: 306 DRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG--HGQ 363
+H G+G + H + + + G G G G+ + G R S RG HG
Sbjct: 1156 -QHGSGLGESSGFGHHESSSGQSSSYSQHGS---GSGHSSGYGQHGSRSGQSSRGERHGS 1211
Query: 364 ALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASG-RHA 422
+ G GQ G G R GHGR G G + G H SG H+
Sbjct: 1212 SSGSSSHY----GQHGSG------SRQSSGHGR------QGSGSGHSPSRGRHGSGLGHS 1255
Query: 423 GEGAPHGKLAGVQEERVPVEELLARQA-RGEAEARQG---ALGQVRGGRVRLHRERREGL 478
HG +G R P E + G+ E+ G A Q G + + G
Sbjct: 1256 SSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGS 1315
Query: 479 LARERARL----FHLGRRCALANRAPALLRAQAASAGRDGGGAMAPQMRLGPQGGERDAG 534
+ + + G+ + +R +Q++ GR G G+ P G +G
Sbjct: 1316 TSGQSSTFDQEGSSTGQSSSYGHRGSG--SSQSSGYGRHGAGS-----GQSPSRGRHGSG 1368
Query: 535 LGRPHQLIHDRLGQGARQRERRRAVGRQRQRG 566
G G G R G + G
Sbjct: 1369 SGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSG 1400
Score = 48.9 bits (115), Expect = 1e-05
Identities = 54/200 (27%), Positives = 71/200 (35%), Gaps = 42/200 (21%)
Query: 246 FGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVR 305
+GRQG G+G G GQ G + Q P RHG G ++
Sbjct: 2055 YGRQGSGSGQSPG-----------------HGQRGSGSRQSPSYGRHGSGSGRSSSSG-- 2095
Query: 306 DRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG--HGQ 363
+H G+G + H + + + G G G G+ + G R S RG HG
Sbjct: 2096 -QHGPGLGESSGFGHHESSSGQSSSYSQHGS---GSGHSSGYGQHGSRSGQSSRGERHGS 2151
Query: 364 ALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGR-HA 422
+ G GQ G G R GHGR G G + G H SG H+
Sbjct: 2152 SSGSSSRY----GQHGSG------SRQSSGHGR------QGSGSGHSPSRGRHGSGSGHS 2195
Query: 423 GEGAPHGKLAGVQEERVPVE 442
HG +G R P E
Sbjct: 2196 SSHGQHGSGSGRSSSRGPYE 2215
Score = 45.4 bits (106), Expect = 1e-04
Identities = 52/198 (26%), Positives = 68/198 (34%), Gaps = 38/198 (19%)
Query: 246 FGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVR 305
+GRQG G+G G GQ G + Q P RHG G ++
Sbjct: 1585 YGRQGSGSGQSPG-----------------HGQRGSGSRQSPSYGRHGSGSGRSSSSG-- 1625
Query: 306 DRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQAL 365
+H G+G + H + + + G G G G+ + G R S R G+
Sbjct: 1626 -QHGSGLGESSGFGHHESSSGQSSSYSQHGS---GSGHSSGYGQHGSRSGQSSR--GERH 1679
Query: 366 GGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASG-RHAGE 424
G GQ G G R GHGR G G G H SG H+
Sbjct: 1680 GSSSRSSSRYGQHGSG------SRQSSGHGR------QGSGSGQSPSRGRHGSGLGHSSS 1727
Query: 425 GAPHGKLAGVQEERVPVE 442
HG +G R P E
Sbjct: 1728 HGQHGSGSGRSSSRGPYE 1745
Score = 42.0 bits (97), Expect = 0.002
Identities = 78/362 (21%), Positives = 112/362 (30%), Gaps = 58/362 (16%)
Query: 250 GHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRR---HG--GQGGGEQTAAV 304
GH + E+ G+ +R H G + G + G R+ HG G G G+ +
Sbjct: 952 GHSSSYEQHGSRSGQSSRSEQH-GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS 1010
Query: 305 RDRHRDGVGAVAQ--PRAHGVQIEEGVAVHRAGGCRRGG-----------------GRRC 345
R RH G G + P G + +G G G
Sbjct: 1011 RGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSS 1070
Query: 346 GHVRV-----GVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQA 400
GH Q+S G A GQ G G G + SG G G
Sbjct: 1071 GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 1130
Query: 401 RDTGGGPRNRGQEGTHASG-----RHAGEGAPHGKLAGVQEERVPVEELLARQARGEAEA 455
R G G R G H SG G+ G+ +G + + G
Sbjct: 1131 R--GSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG 1188
Query: 456 RQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQAASAGRDGG 515
GQ + R R G + + H G+ + + Q++ GR G
Sbjct: 1189 HSSGYGQHGSRSGQSSRGERHGSSSGSSS---HYGQHGSGSR--------QSSGHGRQGS 1237
Query: 516 GAMAPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERRRAVGRQRQRGEERRLVTQH 575
G+ P G +GLG H H + G G+ + R G R + QH
Sbjct: 1238 GS-----GHSPSRGRHGSGLG--HSSSHGQHGSGSGRSSSR---GPYESRSGHSSVFGQH 1287
Query: 576 RA 577
+
Sbjct: 1288 ES 1289
Score = 42.0 bits (97), Expect = 0.002
Identities = 52/198 (26%), Positives = 67/198 (33%), Gaps = 20/198 (10%)
Query: 250 GHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHR 309
G+G G R G + R H R+ + G + HG QG G + R RH
Sbjct: 1662 GYGQHGSRSGQSS--RGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHG 1719
Query: 310 DGVGAVAQPRAHGV----QIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQ-ASERGH--- 361
G+G + HG G R+G G G Q S GH
Sbjct: 1720 SGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCS 1779
Query: 362 -GQ--ALGGQDVLLEVEGQ--GGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTH 416
GQ + GQ + EG G GQ S + G Q +G P G H
Sbjct: 1780 QGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSP----SRGRH 1835
Query: 417 ASGR-HAGEGAPHGKLAG 433
SG H+ HG +G
Sbjct: 1836 GSGSGHSSSYGQHGSGSG 1853
Score = 41.2 bits (95), Expect = 0.003
Identities = 67/304 (22%), Positives = 106/304 (34%), Gaps = 31/304 (10%)
Query: 239 RLFLRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGG 298
RL + +F Q + G+ + H+ GQ G + Q P +G G G
Sbjct: 158 RLSFQRDFSGQHNSYSGQSSSYGEQ---NSDSHQSSGRGQCGSGSGQSP---NYGQHGSG 211
Query: 299 EQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASE 358
++ D H G G + H + + G G G G+ + G R S
Sbjct: 212 SGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGS---GSGHSSGYGQHGSRSGQSS 268
Query: 359 RG--HGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTH 416
RG H + G GQ G G R GHGR G G R H
Sbjct: 269 RGERHRSSSGSSSSY----GQHGSG------SRQSLGHGR------QGSGSRQSPSHVRH 312
Query: 417 ASGR-HAGEGAPHGKLAGVQEERVPVEELLARQAR-GEAEARQG-ALGQVRGGRVRLHRE 473
SG H+ HG + R E + + G+ E+ G + G + G H
Sbjct: 313 GSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGH-S 371
Query: 474 RREGLLARERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMAPQMRLGPQGGERDA 533
+G + G+ + + ++ + + ++AS G G + P G+R +
Sbjct: 372 SSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGS 431
Query: 534 GLGR 537
G G+
Sbjct: 432 GSGQ 435
Score = 40.8 bits (94), Expect = 0.004
Identities = 53/210 (25%), Positives = 68/210 (32%), Gaps = 31/210 (14%)
Query: 250 GHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRR---HGGQGGGEQTAAVRD 306
G+G G R G + R H G + G + G R+ HG QG G + R
Sbjct: 2602 GYGQHGSRSGQSS--RGERH---GSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRG 2656
Query: 307 RHRDGVGAVAQPRAHGV----QIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQ-ASERGH 361
RH G+G + HG G R G G G Q S GH
Sbjct: 2657 RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGH 2716
Query: 362 ----GQ--ALGGQDVLLEVEG-----------QGGRGRPGQSLRRSGRGHGRGIQARDTG 404
GQ + GQ + EG +G R G G G+ + G
Sbjct: 2717 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHG 2776
Query: 405 GGPRNRGQEGTHASGRHAGEG-APHGKLAG 433
G G H SG G + HG +G
Sbjct: 2777 SGSGQSSSYGQHGSGSGQSSGYSQHGSGSG 2806
Score = 40.0 bits (92), Expect = 0.006
Identities = 46/195 (23%), Positives = 65/195 (33%), Gaps = 31/195 (15%)
Query: 250 GHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRR---HGGQGGGEQTAAVRD 306
G+G G R G + +R HR + G + G R+ HG QG G + +
Sbjct: 256 GYGQHGSRSGQS----SRGERHRS-SSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHV 310
Query: 307 RHRDGVGAVAQPRAHGVQIE---------------EGVAVHRAGGCRRGGGRRCGHVRVG 351
RH G G + HG G H +G + G + G G
Sbjct: 311 RHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGS---G 367
Query: 352 VREQASERGHGQALG-----GQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGG 406
+S+ HG G GQ + S SGRG + G G
Sbjct: 368 SGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHG 427
Query: 407 PRNRGQEGTHASGRH 421
R G + +SG+H
Sbjct: 428 QRGSGSGQSPSSGQH 442
Score = 39.7 bits (91), Expect = 0.008
Identities = 49/205 (23%), Positives = 64/205 (31%), Gaps = 24/205 (11%)
Query: 248 RQGHGAGGERGGAAVEFRARVHCH-----RGRAGGQGGDFAVQGPRGRRHG--------- 293
R G + GER G++ +R H + G+ G + Q P RHG
Sbjct: 1669 RSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSH 1728
Query: 294 ---GQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGG---CRRGG-GRRCG 346
G G G ++ R G +V G + H +G C +G G G
Sbjct: 1729 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG 1788
Query: 347 HVRVGVREQAS---ERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDT 403
+E +S HGQ G QG S R G G G
Sbjct: 1789 QSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQH 1848
Query: 404 GGGPRNRGQEGTHASGRHAGEGAPH 428
G G G H SG G H
Sbjct: 1849 GSGSGWSSSSGRHGSGSGQSSGFGH 1873
Score = 38.1 bits (87), Expect = 0.023
Identities = 78/388 (20%), Positives = 119/388 (30%), Gaps = 68/388 (17%)
Query: 271 HRGRAGGQGGDFAVQGP---RGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEE 327
HRG Q + G + G G G ++ +H G G + HG +
Sbjct: 1338 HRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQ 1397
Query: 328 --GVAVH-----RAGGCRR---GGGRRCGHVRVGVREQASERG--HGQALGG-------- 367
G H ++ GC + G G + + G R S RG HG + G
Sbjct: 1398 SSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHG 1457
Query: 368 ----QDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAG 423
Q + G G P S R G G G+ G G G + SG
Sbjct: 1458 SGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHS 1517
Query: 424 EGAPH-----GKLAGVQEERVPVEELLARQARGEAEARQGALGQ--VRGGRVRLHRERRE 476
G H G+ +G + G + + GQ G+ H +
Sbjct: 1518 SGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGS 1577
Query: 477 GLLARERARLFHLGRRCALANRAPALLR-----AQAASAGRDGGGAMAPQMRLGPQGGER 531
G ++ GR+ + + ++P + Q+ S GR G G+ G+
Sbjct: 1578 G-----SSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS-----GRSSSSGQH 1627
Query: 532 DAGLGRPHQLIHDRLGQGARQRERRRAVG------------------RQRQRGEERRLVT 573
+GLG H G + G R + G R +
Sbjct: 1628 GSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSS 1687
Query: 574 QHRAHGE-VRRPKREERAGSRLAPEPCR 600
++ HG R+ R GS P R
Sbjct: 1688 RYGQHGSGSRQSSGHGRQGSGSGQSPSR 1715
Score = 37.7 bits (86), Expect = 0.030
Identities = 49/205 (23%), Positives = 62/205 (30%), Gaps = 24/205 (11%)
Query: 248 RQGHGAGGERGGAAVEFRARVHCH---------RGRAGGQGGDFAVQGPRGRRHG----- 293
R G + GER G++ +R H GR G G +G G G
Sbjct: 2139 RSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSH 2198
Query: 294 ---GQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGG---CRRGG-GRRCG 346
G G G ++ R G +V G + H +G C +G G G
Sbjct: 2199 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG 2258
Query: 347 HVRVGVREQAS---ERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDT 403
+E +S HGQ G QG S R G G G
Sbjct: 2259 QSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQH 2318
Query: 404 GGGPRNRGQEGTHASGRHAGEGAPH 428
G G G H SG G H
Sbjct: 2319 GSGSGWSSSSGRHGSGSGQSSGFGH 2343
Score = 37.0 bits (84), Expect = 0.052
Identities = 72/351 (20%), Positives = 109/351 (31%), Gaps = 63/351 (17%)
Query: 244 AEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAA 303
+ +G+QG G+G RGR G G +G G G ++
Sbjct: 1817 SSYGQQGSGSGQSPS-------------RGRHGSGSG-------HSSSYGQHGSGSGWSS 1856
Query: 304 VRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGG--RRCGHVRVGVREQASERG- 360
RH G G ++ G E + +G + G G + + G R S RG
Sbjct: 1857 SSGRHGSGSG-----QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE 1911
Query: 361 -HGQALGG------------QDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGP 407
HG + G Q + G G P S R G G G+ G G
Sbjct: 1912 QHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGS 1971
Query: 408 RNRGQEGTHASGRHAGEGAPH-----GKLAGVQEERVPVEELLARQARGEAEARQGALGQ 462
G + SG G H G+ +G + G A + + GQ
Sbjct: 1972 GWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQ 2031
Query: 463 --VRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLR-----AQAASAGRDGG 515
G+ H + G ++ GR+ + + ++P + Q+ S GR G
Sbjct: 2032 HGASSGQSSSHGQHGSG-----SSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 2086
Query: 516 GAMAPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERRRAVGRQRQRG 566
G+ G+ GLG H G + G G
Sbjct: 2087 GS-----GRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 2132
Score = 36.6 bits (83), Expect = 0.068
Identities = 71/351 (20%), Positives = 109/351 (31%), Gaps = 63/351 (17%)
Query: 244 AEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAA 303
+ +G+QG G+G RGR G G +G G G ++
Sbjct: 2287 SSYGQQGSGSGQSPS-------------RGRHGSGSG-------HSSSYGQHGSGSGWSS 2326
Query: 304 VRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGG--RRCGHVRVGVREQASERG- 360
RH G G ++ G E + +G + G G + + G R S RG
Sbjct: 2327 SSGRHGSGSG-----QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE 2381
Query: 361 -HGQALGG------------QDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGP 407
HG + G Q + G G P S R G G G+ G G
Sbjct: 2382 RHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS 2441
Query: 408 RNRGQEGTHASGRHAGEGAPH-----GKLAGVQEERVPVEELLARQARGEAEARQGALGQ 462
G + SG G H G+ +G + G + + GQ
Sbjct: 2442 GWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQ 2501
Query: 463 --VRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLR-----AQAASAGRDGG 515
G+ H + G ++ GR+ + + ++P + Q+ S GR G
Sbjct: 2502 HGASSGQSSSHGQHGSG-----SSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 2556
Query: 516 GAMAPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERRRAVGRQRQRG 566
G+ G+ +GLG H G + G G
Sbjct: 2557 GS-----GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 2602
Score = 36.2 bits (82), Expect = 0.089
Identities = 53/219 (24%), Positives = 70/219 (31%), Gaps = 47/219 (21%)
Query: 250 GHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRR---HGGQGGGEQTAAVRD 306
G+G G R G + R H G + G + G R+ HG QG G + R
Sbjct: 1192 GYGQHGSRSGQSS--RGERH---GSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRG 1246
Query: 307 RHRDGVGAVAQPRAHGV----------------------QIEEG------VAVHRAGG-- 336
RH G+G + HG Q E G + H +G
Sbjct: 1247 RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 1306
Query: 337 -CRRGG-GRRCGHVRVGVRE-----QASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRR 389
C +G G G +E Q+S GH + Q G G P +
Sbjct: 1307 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHG 1366
Query: 390 SGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPH 428
SG GH +G G + G H SG G H
Sbjct: 1367 SGSGHSSSYGQHGSGSGWSS--SSGRHGSGSGQSSGFGH 1403
Score = 34.3 bits (77), Expect = 0.34
Identities = 36/160 (22%), Positives = 48/160 (30%), Gaps = 21/160 (13%)
Query: 271 HRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVA 330
H G+ G + Q P HG +G G + RH G G + HG G
Sbjct: 875 HHASGRGRHGSGSGQSPG---HGQRGSGSGQSPSYGRHGSGSGRSSSSGRHG----SGSG 927
Query: 331 VHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRS 390
G + G+ G+ + G S GH + E G R +
Sbjct: 928 QSSGFGHKSSSGQSSGYTQHG-----SGSGHSSSY---------EQHGSRSGQSSRSEQH 973
Query: 391 GRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGK 430
G G G G R G H SG G+
Sbjct: 974 GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGR 1013
Score = 33.5 bits (75), Expect = 0.57
Identities = 48/228 (21%), Positives = 69/228 (30%), Gaps = 15/228 (6%)
Query: 207 SGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFR- 265
SG G G +G G + + + + R G HG+G + + R
Sbjct: 489 SGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRH 548
Query: 266 ---ARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGG-GEQTAAVRDRHRDGVGAVAQPRAH 321
+R G G G + +GP G G G Q + R G G H
Sbjct: 549 ESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQES--RSGQSSGYGQHGSSSGH 606
Query: 322 GVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRG 381
+ H G G CG + +S HG Q +G G
Sbjct: 607 S-------STHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSG-SSQSSRYGQQGSGSGQ 658
Query: 382 RPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHG 429
P + S GH +G G + SG+ +G G G
Sbjct: 659 SPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSG 706
Score = 33.5 bits (75), Expect = 0.57
Identities = 40/160 (25%), Positives = 54/160 (33%), Gaps = 28/160 (17%)
Query: 276 GGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAG 335
G G F+ QG RHG G ++ D + Q ++G E + H +G
Sbjct: 832 GSASGHFSSQG----RHGSTSGQSSSSGQHD------SSSGQSSSYGQH--ESASHHASG 879
Query: 336 GCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQG-GRGRPGQSLRR-SGRG 393
R G G GHGQ G G G GR S R SG G
Sbjct: 880 RGRHGSG------------SGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSG 927
Query: 394 HGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAG 433
G + + G Q G+ + H+ HG +G
Sbjct: 928 QSSGFGHKSSSGQSSGYTQHGSGSG--HSSSYEQHGSRSG 965
Score = 32.7 bits (73), Expect = 0.98
Identities = 46/197 (23%), Positives = 67/197 (34%), Gaps = 39/197 (19%)
Query: 246 FGRQGHGAG---GERGGAAVEFRARVHCHRGRAGGQGGDFAVQGP------RGRRHGGQG 296
FG+ G+G + G A+ F ++ GR G G + G + +G
Sbjct: 817 FGQHESGSGQGYSQHGSASGHFSSQ-----GRHGSTSGQSSSSGQHDSSSGQSSSYGQHE 871
Query: 297 GGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQA 356
A+ R RH G G Q HG + G G G G +
Sbjct: 872 SASHHASGRGRHGSGSG---QSPGHGQR-----------GSGSGQSPSYGRHGSGSGRSS 917
Query: 357 SERGHGQALGGQDVLLEVEGQGGRGRPGQSL----RRSGRGHGRGIQARDTGGGPRNRGQ 412
S HG G + G G + GQS SG GH + + G +R +
Sbjct: 918 SSGRHGSGSG------QSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSE 971
Query: 413 EGTHASGRHAGEGAPHG 429
+ +SG + G HG
Sbjct: 972 QHGSSSGSSSSYG-QHG 987
Score = 32.7 bits (73), Expect = 0.98
Identities = 43/192 (22%), Positives = 67/192 (34%), Gaps = 39/192 (20%)
Query: 246 FGRQGHGAG-----GERGGAAVEFRARVHCHRGRAGGQGGDFAVQGP---RGRRHGGQGG 297
+ + G G+G G+ G + + + G + GQ G + +G QG
Sbjct: 1767 YSQHGSGSGHFCSQGQHGSTSGQ--SSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGS 1824
Query: 298 GEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQAS 357
G + R RH G G + HG G + G R G G Q+S
Sbjct: 1825 GSGQSPSRGRHGSGSGHSSSYGQHG----SGSGWSSSSG-RHGSGSG----------QSS 1869
Query: 358 ERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHA 417
GH ++ Q G + SG GH + + G +RG++ +
Sbjct: 1870 GFGHHESSSWQS-------------SGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSS 1916
Query: 418 SGRHAGEGAPHG 429
SG + G HG
Sbjct: 1917 SGSSSSYG-QHG 1927
Score = 32.3 bits (72), Expect = 1.3
Identities = 53/224 (23%), Positives = 66/224 (29%), Gaps = 47/224 (20%)
Query: 251 HGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRR---HGGQGGGEQTAAVRDR 307
H +G + G+ +R H G + G + G + HG QG G + R R
Sbjct: 722 HSSGYRKHGSRSGQSSRSEQH-GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVR 780
Query: 308 HRDGVGAVAQPRAHGV---------QIEEGVAVHRAGGCRRGG--------GRRCGHVRV 350
H G + HG E G G G G GH
Sbjct: 781 HGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSS 840
Query: 351 GVRE-----QASERGHGQALGGQDVLLEVEGQ--------GGRGR--------PGQSLRR 389
R Q+S G + GQ GQ GRGR PG R
Sbjct: 841 QGRHGSTSGQSSSSGQHDSSSGQS---SSYGQHESASHHASGRGRHGSGSGQSPGHGQRG 897
Query: 390 SGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAG 433
SG G +G G G H SG G H +G
Sbjct: 898 SGSGQSPSYGRHGSGSG--RSSSSGRHGSGSGQSSGFGHKSSSG 939
>gi|169171347 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1128
Score = 52.0 bits (123), Expect = 2e-06
Identities = 69/218 (31%), Positives = 85/218 (38%), Gaps = 27/218 (12%)
Query: 371 LLEVEGQGGRGRPGQSLRRSG-----RGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEG 425
L E G+G R S + +G GH + RD GG +RG+EG G AG G
Sbjct: 382 LAESRGRGVTPRASWSRQPAGGPLSSEGHLLPLVQRDGGGLAEHRGREGEE--GVRAGGG 439
Query: 426 APHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERAR 485
G R PV G A +GA VRG V ERR E A+
Sbjct: 440 GTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQS-VRGPGV----ERR----VAEGAQ 490
Query: 486 LFHLGRRCALANRAPALLRAQAASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQLIHDR 545
F G R L A + RAQ A+ GR GGG G Q R G G Q+ +
Sbjct: 491 QF--GPRVGLRQHAERVERAQRAAEGRGGGGGGG----CGAQAHRRVVGQG---QVRWEG 541
Query: 546 LGQGARQRERRR--AVGRQRQRGEERRLVTQHRAHGEV 581
+GQ AR R + GR Q + H H E+
Sbjct: 542 VGQAARGRRMAHHCSQGRNSQSRHQPGRDRPHHHHLEL 579
Score = 42.7 bits (99), Expect = 0.001
Identities = 53/182 (29%), Positives = 68/182 (37%), Gaps = 27/182 (14%)
Query: 271 HRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVA 330
HRGR G +G G R GG G + G GA + G Q G
Sbjct: 425 HRGREGEEGVRAGGGGTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGR----GAQSVRGPG 480
Query: 331 VHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRS 390
V R R G + RVG+R+ A Q EG+GG G G +
Sbjct: 481 VER----RVAEGAQQFGPRVGLRQHAERVERAQR--------AAEGRGGGGGGGCGAQAH 528
Query: 391 GRGHGRGIQARDTGGGPRNRGQ-------EGTHASGRH-AGEGAPHGKLAGVQ--EERVP 440
R G+G Q R G G RG+ +G ++ RH G PH ++ ERVP
Sbjct: 529 RRVVGQG-QVRWEGVGQAARGRRMAHHCSQGRNSQSRHQPGRDRPHHHHLELESLRERVP 587
Query: 441 VE 442
E
Sbjct: 588 CE 589
Score = 35.4 bits (80), Expect = 0.15
Identities = 44/154 (28%), Positives = 56/154 (36%), Gaps = 21/154 (13%)
Query: 242 LRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQT 301
+RA G G GG G RA V G G +V+GP R +G +
Sbjct: 434 VRAGGGGTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQSVRGPGVERRVAEGAQQ-- 491
Query: 302 AAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCG---HVRVGVREQASE 358
G R H ++E A A G GGG CG H RV + Q
Sbjct: 492 ----------FGPRVGLRQHAERVER--AQRAAEGRGGGGGGGCGAQAHRRVVGQGQVRW 539
Query: 359 RGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGR 392
G GQA G+ + +GR QS + GR
Sbjct: 540 EGVGQAARGR----RMAHHCSQGRNSQSRHQPGR 569
Score = 31.2 bits (69), Expect = 2.8
Identities = 35/126 (27%), Positives = 49/126 (38%), Gaps = 15/126 (11%)
Query: 207 SGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGR------QGHGAGGERGGA 260
+G G GR A VR G + + Q G R+ LR R G GG GG
Sbjct: 464 AGAGAAGRGAQSVR-GPGVERRVAEGAQQFGPRVGLRQHAERVERAQRAAEGRGGGGGGG 522
Query: 261 AVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRA 320
R +G+ +G A +G R H QG Q+ RH+ G +P
Sbjct: 523 CGAQAHRRVVGQGQVRWEGVGQAARGRRMAHHCSQGRNSQS-----RHQPGRD---RPHH 574
Query: 321 HGVQIE 326
H +++E
Sbjct: 575 HHLELE 580
>gi|169172209 PREDICTED: hypothetical protein [Homo sapiens]
Length = 801
Score = 52.0 bits (123), Expect = 2e-06
Identities = 69/218 (31%), Positives = 85/218 (38%), Gaps = 27/218 (12%)
Query: 371 LLEVEGQGGRGRPGQSLRRSG-----RGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEG 425
L E G+G R S + +G GH + RD GG +RG+EG G AG G
Sbjct: 55 LAESRGRGVTPRASWSRQPAGGPLSSEGHLLPLVQRDGGGLAEHRGREGEE--GVRAGGG 112
Query: 426 APHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERAR 485
G R PV G A +GA VRG V ERR E A+
Sbjct: 113 GTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQS-VRGPGV----ERR----VAEGAQ 163
Query: 486 LFHLGRRCALANRAPALLRAQAASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQLIHDR 545
F G R L A + RAQ A+ GR GGG G Q R G G Q+ +
Sbjct: 164 QF--GPRVGLRQHAERVERAQRAAEGRGGGGGGG----CGAQAHRRVVGQG---QVRWEG 214
Query: 546 LGQGARQRERRR--AVGRQRQRGEERRLVTQHRAHGEV 581
+GQ AR R + GR Q + H H E+
Sbjct: 215 VGQAARGRRMAHHCSQGRNSQSRHQPGRDRPHHHHLEL 252
Score = 42.7 bits (99), Expect = 0.001
Identities = 53/182 (29%), Positives = 68/182 (37%), Gaps = 27/182 (14%)
Query: 271 HRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVA 330
HRGR G +G G R GG G + G GA + G Q G
Sbjct: 98 HRGREGEEGVRAGGGGTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGR----GAQSVRGPG 153
Query: 331 VHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRS 390
V R R G + RVG+R+ A Q EG+GG G G +
Sbjct: 154 VER----RVAEGAQQFGPRVGLRQHAERVERAQR--------AAEGRGGGGGGGCGAQAH 201
Query: 391 GRGHGRGIQARDTGGGPRNRGQ-------EGTHASGRH-AGEGAPHGKLAGVQ--EERVP 440
R G+G Q R G G RG+ +G ++ RH G PH ++ ERVP
Sbjct: 202 RRVVGQG-QVRWEGVGQAARGRRMAHHCSQGRNSQSRHQPGRDRPHHHHLELESLRERVP 260
Query: 441 VE 442
E
Sbjct: 261 CE 262
Score = 35.4 bits (80), Expect = 0.15
Identities = 44/154 (28%), Positives = 56/154 (36%), Gaps = 21/154 (13%)
Query: 242 LRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQT 301
+RA G G GG G RA V G G +V+GP R +G +
Sbjct: 107 VRAGGGGTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQSVRGPGVERRVAEGAQQ-- 164
Query: 302 AAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCG---HVRVGVREQASE 358
G R H ++E A A G GGG CG H RV + Q
Sbjct: 165 ----------FGPRVGLRQHAERVER--AQRAAEGRGGGGGGGCGAQAHRRVVGQGQVRW 212
Query: 359 RGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGR 392
G GQA G+ + +GR QS + GR
Sbjct: 213 EGVGQAARGR----RMAHHCSQGRNSQSRHQPGR 242
Score = 31.2 bits (69), Expect = 2.8
Identities = 35/126 (27%), Positives = 49/126 (38%), Gaps = 15/126 (11%)
Query: 207 SGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGR------QGHGAGGERGGA 260
+G G GR A VR G + + Q G R+ LR R G GG GG
Sbjct: 137 AGAGAAGRGAQSVR-GPGVERRVAEGAQQFGPRVGLRQHAERVERAQRAAEGRGGGGGGG 195
Query: 261 AVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRA 320
R +G+ +G A +G R H QG Q+ RH+ G +P
Sbjct: 196 CGAQAHRRVVGQGQVRWEGVGQAARGRRMAHHCSQGRNSQS-----RHQPGRD---RPHH 247
Query: 321 HGVQIE 326
H +++E
Sbjct: 248 HHLELE 253
>gi|169170953 PREDICTED: hypothetical protein [Homo sapiens]
Length = 801
Score = 52.0 bits (123), Expect = 2e-06
Identities = 69/218 (31%), Positives = 85/218 (38%), Gaps = 27/218 (12%)
Query: 371 LLEVEGQGGRGRPGQSLRRSG-----RGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEG 425
L E G+G R S + +G GH + RD GG +RG+EG G AG G
Sbjct: 55 LAESRGRGVTPRASWSRQPAGGPLSSEGHLLPLVQRDGGGLAEHRGREGEE--GVRAGGG 112
Query: 426 APHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERAR 485
G R PV G A +GA VRG V ERR E A+
Sbjct: 113 GTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQS-VRGPGV----ERR----VAEGAQ 163
Query: 486 LFHLGRRCALANRAPALLRAQAASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQLIHDR 545
F G R L A + RAQ A+ GR GGG G Q R G G Q+ +
Sbjct: 164 QF--GPRVGLRQHAERVERAQRAAEGRGGGGGGG----CGAQAHRRVVGQG---QVRWEG 214
Query: 546 LGQGARQRERRR--AVGRQRQRGEERRLVTQHRAHGEV 581
+GQ AR R + GR Q + H H E+
Sbjct: 215 VGQAARGRRMAHHCSQGRNSQSRHQPGRDRPHHHHLEL 252
Score = 42.7 bits (99), Expect = 0.001
Identities = 53/182 (29%), Positives = 68/182 (37%), Gaps = 27/182 (14%)
Query: 271 HRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVA 330
HRGR G +G G R GG G + G GA + G Q G
Sbjct: 98 HRGREGEEGVRAGGGGTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGR----GAQSVRGPG 153
Query: 331 VHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRS 390
V R R G + RVG+R+ A Q EG+GG G G +
Sbjct: 154 VER----RVAEGAQQFGPRVGLRQHAERVERAQR--------AAEGRGGGGGGGCGAQAH 201
Query: 391 GRGHGRGIQARDTGGGPRNRGQ-------EGTHASGRH-AGEGAPHGKLAGVQ--EERVP 440
R G+G Q R G G RG+ +G ++ RH G PH ++ ERVP
Sbjct: 202 RRVVGQG-QVRWEGVGQAARGRRMAHHCSQGRNSQSRHQPGRDRPHHHHLELESLRERVP 260
Query: 441 VE 442
E
Sbjct: 261 CE 262
Score = 35.4 bits (80), Expect = 0.15
Identities = 44/154 (28%), Positives = 56/154 (36%), Gaps = 21/154 (13%)
Query: 242 LRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQT 301
+RA G G GG G RA V G G +V+GP R +G +
Sbjct: 107 VRAGGGGTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQSVRGPGVERRVAEGAQQ-- 164
Query: 302 AAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCG---HVRVGVREQASE 358
G R H ++E A A G GGG CG H RV + Q
Sbjct: 165 ----------FGPRVGLRQHAERVER--AQRAAEGRGGGGGGGCGAQAHRRVVGQGQVRW 212
Query: 359 RGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGR 392
G GQA G+ + +GR QS + GR
Sbjct: 213 EGVGQAARGR----RMAHHCSQGRNSQSRHQPGR 242
Score = 31.2 bits (69), Expect = 2.8
Identities = 35/126 (27%), Positives = 49/126 (38%), Gaps = 15/126 (11%)
Query: 207 SGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGR------QGHGAGGERGGA 260
+G G GR A VR G + + Q G R+ LR R G GG GG
Sbjct: 137 AGAGAAGRGAQSVR-GPGVERRVAEGAQQFGPRVGLRQHAERVERAQRAAEGRGGGGGGG 195
Query: 261 AVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRA 320
R +G+ +G A +G R H QG Q+ RH+ G +P
Sbjct: 196 CGAQAHRRVVGQGQVRWEGVGQAARGRRMAHHCSQGRNSQS-----RHQPGRD---RPHH 247
Query: 321 HGVQIE 326
H +++E
Sbjct: 248 HHLELE 253
>gi|239508753 PREDICTED: hypothetical protein [Homo sapiens]
Length = 801
Score = 52.0 bits (123), Expect = 2e-06
Identities = 69/218 (31%), Positives = 85/218 (38%), Gaps = 27/218 (12%)
Query: 371 LLEVEGQGGRGRPGQSLRRSG-----RGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEG 425
L E G+G R S + +G GH + RD GG +RG+EG G AG G
Sbjct: 55 LAESRGRGVTPRASWSRQPAGGPLSSEGHLLPLVQRDGGGLAEHRGREGEE--GVRAGGG 112
Query: 426 APHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERAR 485
G R PV G A +GA VRG V ERR E A+
Sbjct: 113 GTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQS-VRGPGV----ERR----VAEGAQ 163
Query: 486 LFHLGRRCALANRAPALLRAQAASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQLIHDR 545
F G R L A + RAQ A+ GR GGG G Q R G G Q+ +
Sbjct: 164 QF--GPRVGLRQHAERVERAQRAAEGRGGGGGGG----CGAQAHRRVVGQG---QVRWEG 214
Query: 546 LGQGARQRERRR--AVGRQRQRGEERRLVTQHRAHGEV 581
+GQ AR R + GR Q + H H E+
Sbjct: 215 VGQAARGRRMAHHCSQGRNSQSRHQPGRDRPHHHHLEL 252
Score = 42.7 bits (99), Expect = 0.001
Identities = 53/182 (29%), Positives = 68/182 (37%), Gaps = 27/182 (14%)
Query: 271 HRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVA 330
HRGR G +G G R GG G + G GA + G Q G
Sbjct: 98 HRGREGEEGVRAGGGGTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGR----GAQSVRGPG 153
Query: 331 VHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRS 390
V R R G + RVG+R+ A Q EG+GG G G +
Sbjct: 154 VER----RVAEGAQQFGPRVGLRQHAERVERAQR--------AAEGRGGGGGGGCGAQAH 201
Query: 391 GRGHGRGIQARDTGGGPRNRGQ-------EGTHASGRH-AGEGAPHGKLAGVQ--EERVP 440
R G+G Q R G G RG+ +G ++ RH G PH ++ ERVP
Sbjct: 202 RRVVGQG-QVRWEGVGQAARGRRMAHHCSQGRNSQSRHQPGRDRPHHHHLELESLRERVP 260
Query: 441 VE 442
E
Sbjct: 261 CE 262
Score = 35.4 bits (80), Expect = 0.15
Identities = 44/154 (28%), Positives = 56/154 (36%), Gaps = 21/154 (13%)
Query: 242 LRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQT 301
+RA G G GG G RA V G G +V+GP R +G +
Sbjct: 107 VRAGGGGTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQSVRGPGVERRVAEGAQQ-- 164
Query: 302 AAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCG---HVRVGVREQASE 358
G R H ++E A A G GGG CG H RV + Q
Sbjct: 165 ----------FGPRVGLRQHAERVER--AQRAAEGRGGGGGGGCGAQAHRRVVGQGQVRW 212
Query: 359 RGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGR 392
G GQA G+ + +GR QS + GR
Sbjct: 213 EGVGQAARGR----RMAHHCSQGRNSQSRHQPGR 242
Score = 31.2 bits (69), Expect = 2.8
Identities = 35/126 (27%), Positives = 49/126 (38%), Gaps = 15/126 (11%)
Query: 207 SGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGR------QGHGAGGERGGA 260
+G G GR A VR G + + Q G R+ LR R G GG GG
Sbjct: 137 AGAGAAGRGAQSVR-GPGVERRVAEGAQQFGPRVGLRQHAERVERAQRAAEGRGGGGGGG 195
Query: 261 AVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRA 320
R +G+ +G A +G R H QG Q+ RH+ G +P
Sbjct: 196 CGAQAHRRVVGQGQVRWEGVGQAARGRRMAHHCSQGRNSQS-----RHQPGRD---RPHH 247
Query: 321 HGVQIE 326
H +++E
Sbjct: 248 HHLELE 253
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 51.6 bits (122), Expect = 2e-06
Identities = 52/206 (25%), Positives = 69/206 (33%), Gaps = 25/206 (12%)
Query: 247 GRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRD 306
G GHG +RG RA H + G G G GE ++V +
Sbjct: 2008 GHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHE 2067
Query: 307 RHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGH-------VRVGVREQASER 359
RH G H G G R G R GH V GV S
Sbjct: 2068 RHGTTHGQTGDTTRHA---HSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGH 2124
Query: 360 GHGQALGGQ-DVLLEVEGQGG--RGRPGQSLRRSGRGHGRGIQARD-TGGGPRNRGQEG- 414
+GQA + + G+ G G+ G + R GHG+ Q T G R+ E
Sbjct: 2125 TYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESS 2184
Query: 415 ----------THASGRHAGEGAPHGK 430
TH+ H+ G+ HG+
Sbjct: 2185 DSEVHSEASPTHSGHTHSQAGSRHGQ 2210
Score = 47.4 bits (111), Expect = 4e-05
Identities = 82/345 (23%), Positives = 105/345 (30%), Gaps = 51/345 (14%)
Query: 245 EFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGG--EQTA 302
E G HG + G R H + G G G HG G E +
Sbjct: 1931 EHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHS--GHTHGQAGSHYPESGS 1988
Query: 303 AVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRV-------GVREQ 355
+V +RH G A HG G G R G R GH GV
Sbjct: 1989 SVHERHGTTHGQTADTTRHG---HSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHT 2045
Query: 356 ASERGHGQALGGQDVLLEVEGQGG----------RGRPGQSLRRSGRGHGRGIQARDTGG 405
S HGQA G Q G+ G G+ G + R + GHG+ Q
Sbjct: 2046 HSGHAHGQA-GSQ------HGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTA 2098
Query: 406 GPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLARQARGEA-EARQGALGQVR 464
G R G + S H+G H Q AR GE+ A G G +
Sbjct: 2099 GRRGSGHSESSDSEVHSGVSHTHSGHTYGQ----------ARSQHGESGSAIHGRQGTIH 2148
Query: 465 G--GRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMAPQM 522
G G H + G + +R GR+ + + + AS G
Sbjct: 2149 GQTGDTTRHGQSGHGQSTQTGSRT--TGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGS 2206
Query: 523 RLGPQGGERDAGLGRPH-----QLIHDRLGQGARQRERRRAVGRQ 562
R G G G H H G G + R GR+
Sbjct: 2207 RHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRR 2251
Score = 45.4 bits (106), Expect = 1e-04
Identities = 50/198 (25%), Positives = 64/198 (32%), Gaps = 20/198 (10%)
Query: 250 GHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGG--GEQTAAVRDR 307
GHG + G R+ H + G G RG HG G GE + V +R
Sbjct: 1784 GHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGESESIVDER 1843
Query: 308 HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGH-------VRVGVREQASERG 360
H G H + G G G RR GH V G S
Sbjct: 1844 HGTTHGQTGDTSGHS---QSGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHT 1900
Query: 361 HGQAL---GGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRG-QEGTH 416
H QA G + + Q G+ G + HG+ IQ G R G E +
Sbjct: 1901 HSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSD 1960
Query: 417 ASG----RHAGEGAPHGK 430
+ G H G HG+
Sbjct: 1961 SEGPSGVSHTHSGHTHGQ 1978
Score = 42.0 bits (97), Expect = 0.002
Identities = 47/195 (24%), Positives = 63/195 (32%), Gaps = 12/195 (6%)
Query: 247 GRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGG--GEQTAAV 304
G GHG +RG R H + G + + HG G GE + V
Sbjct: 1402 GHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTV 1461
Query: 305 RDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGC--RRGGGR---RCGHVRVGVREQASER 359
RH G H G + R RRG G V G S
Sbjct: 1462 HGRHGTTHGQTGDTTRH-AHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGH 1520
Query: 360 GHGQA---LGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARD-TGGGPRNRGQEGT 415
HGQ+ G + ++ + G+ G + R S GH + Q T G R E T
Sbjct: 1521 THGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSEST 1580
Query: 416 HASGRHAGEGAPHGK 430
+ G PH +
Sbjct: 1581 DSEVHSGGSHRPHSR 1595
Score = 42.0 bits (97), Expect = 0.002
Identities = 57/241 (23%), Positives = 77/241 (31%), Gaps = 52/241 (21%)
Query: 245 EFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHG----------- 293
E G HG G G + H H G++ +G + G RG H
Sbjct: 1456 ESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGS--STTGRRGSGHSESSDSEVHSGG 1513
Query: 294 ---------GQGG---GEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGG 341
GQ G GE + + DRHR G H E G R G
Sbjct: 1514 SHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTT---QTGSRTTG 1570
Query: 342 GRRCGH-------VRVGVREQASERGHGQALGG---QDVLLEVEGQGG--RGRPGQSLRR 389
+R H V G + R H G ++ V + G G+ G +
Sbjct: 1571 RQRTSHSESTDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGH 1630
Query: 390 SGRGHGRGIQ--ARDTG----------GGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEE 437
S GHG+ Q +R TG + G TH H G+ HG+ + E
Sbjct: 1631 SHSGHGQSTQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESIVPE 1690
Query: 438 R 438
R
Sbjct: 1691 R 1691
Score = 40.0 bits (92), Expect = 0.006
Identities = 42/197 (21%), Positives = 60/197 (30%), Gaps = 20/197 (10%)
Query: 251 HGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRD 310
HG + G R H + G G GE + V +RH
Sbjct: 1710 HGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGT 1769
Query: 311 GVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRV-------GVREQASERGH-- 361
G H G G R G R GH G ++ RGH
Sbjct: 1770 IHGQTGDTTRHA---HSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTH 1826
Query: 362 ---GQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGT--- 415
G G + +++ G+ G + S GHG+ Q+ + G R G +
Sbjct: 1827 GQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDS 1886
Query: 416 --HASGRHAGEGAPHGK 430
H+ G H G H +
Sbjct: 1887 EVHSGGSHTHSGHTHSQ 1903
Score = 35.4 bits (80), Expect = 0.15
Identities = 81/375 (21%), Positives = 119/375 (31%), Gaps = 80/375 (21%)
Query: 246 FGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVR 305
FG+ G G+G G E R+R + GQ G + Q +HG G QT+
Sbjct: 1051 FGQHGTGSGQSSGFGQYESRSRQSSY-----GQHGSGSSQSSGYGQHGSNSG--QTS--- 1100
Query: 306 DRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQAL 365
G HR G + G G G + + HG
Sbjct: 1101 ----------------------GFGQHRPGSGQSSG---FGQYGSGSGQSSGFGQHGSGT 1135
Query: 366 GGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRN------RGQEGTHASG 419
G + E + G+ GQ +G G ++G GP G + +SG
Sbjct: 1136 GKSSGFAQHEYRSGQSSYGQ--HGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSG 1193
Query: 420 RHAGE----------GAPHGKLAGV-QEERVPVE---------ELLARQARGEAEARQGA 459
+H + G+ G+ G+ Q E VE E Q Q
Sbjct: 1194 QHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQTINTTRHSQSG 1253
Query: 460 LGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMA 519
GQ R+ R RR + + +++R + QA S G +
Sbjct: 1254 QGQSTQTGSRVTRRRRSSQSENSDSEV-----HSKVSHRHSEHIHTQAGSHYPKSGSTV- 1307
Query: 520 PQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERRRAVGRQRQRGEERRLVTQHRAH- 578
+ R G G+R H G G + R GRQR + T H
Sbjct: 1308 -RRRQGTTHGQRG------DTTRHGHSGHGQSTQTGSRTSGRQRFSHSD---ATDSEVHS 1357
Query: 579 GEVRRPKREERAGSR 593
G RP +E+ S+
Sbjct: 1358 GVSHRPHSQEQTHSQ 1372
Score = 35.0 bits (79), Expect = 0.20
Identities = 54/247 (21%), Positives = 78/247 (31%), Gaps = 39/247 (15%)
Query: 244 AEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAA 303
A FG+ G G+G G E R+ + GQ G + Q +HG G QT+
Sbjct: 818 AGFGQHGSGSGQSSGFGQHESRSHQSSY-----GQHGSGSSQSSGYGQHGSSSG--QTSG 870
Query: 304 VRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG--- 360
+HR G + HG + + G G G+ G + R S G
Sbjct: 871 F-GQHRSSSGQYSGFGQHGSGSGQSSGFGQHG---TGSGQYSGFGQHESRSHQSSYGQHG 926
Query: 361 -----------HGQALG------------GQDVLLEVEGQGGRGRPGQSLRRSGRGHGRG 397
HG + G GQ G G G SG G G
Sbjct: 927 SGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSG 986
Query: 398 IQARDTGGGPRNRGQEGTHA--SGRHAGEGAPHGKLAGVQEERVPVEELLARQARGEAEA 455
++ N GQ G+ + S + G+ G+ G + R + G
Sbjct: 987 FGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSD 1046
Query: 456 RQGALGQ 462
+ GQ
Sbjct: 1047 QSSGFGQ 1053
Score = 33.9 bits (76), Expect = 0.44
Identities = 85/383 (22%), Positives = 124/383 (32%), Gaps = 66/383 (17%)
Query: 251 HGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHG-------GQGGGEQTAA 303
H G+ G + + +RV R + + D V RH G + +
Sbjct: 1249 HSQSGQ--GQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGST 1306
Query: 304 VRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGH-------VRVGV--RE 354
VR R G HG G G R G +R H V GV R
Sbjct: 1307 VRRRQGTTHGQRGDTTRHG---HSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRP 1363
Query: 355 QASERGHGQA---LGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRG 411
+ E+ H QA G + + + G+ G++ GHG+ Q G R G
Sbjct: 1364 HSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGRRGSG 1423
Query: 412 QEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLH 471
+ S H+G G +E Q G+A ++ G G GR H
Sbjct: 1424 HSESSDSEVHSG-----GSHRPQSQE----------QTHGQAGSQHGESGSTVHGR---H 1465
Query: 472 RERREGLLARERARLFHLG----RRCALANRAPALLRAQAASAGRDGGG---AMAPQMRL 524
R +H G R + R + + S GG + +
Sbjct: 1466 GTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQS 1525
Query: 525 GPQGGERDAGLGRPHQLIHDRLGQGARQ---------RERRRAVGRQRQRGEERRLVTQH 575
G Q GE ++ + H++ H + G R + R GRQR E T
Sbjct: 1526 GSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSES---TDS 1582
Query: 576 RAH-GEVRRPKREE----RAGSR 593
H G RP E +AGS+
Sbjct: 1583 EVHSGGSHRPHSREHTYGQAGSQ 1605
Score = 33.9 bits (76), Expect = 0.44
Identities = 48/197 (24%), Positives = 58/197 (29%), Gaps = 17/197 (8%)
Query: 251 HGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRD 310
HG + G E + VH G GQ GD G Q G T H +
Sbjct: 1749 HGQARSQHG---ESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSE 1805
Query: 311 -----GVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCG--HVRVGVREQASERGHGQ 363
G +Q R H G A + G R G H + G S+ GHGQ
Sbjct: 1806 YSDSEGHSGFSQ-RPHSRGHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQ 1864
Query: 364 ALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAG 423
+ GR R G S H G + R Q G S H
Sbjct: 1865 STQSGS------STTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKR 1918
Query: 424 EGAPHGKLAGVQEERVP 440
HG+ E P
Sbjct: 1919 HQTTHGQTGDTTEHGHP 1935
Score = 33.1 bits (74), Expect = 0.75
Identities = 46/234 (19%), Positives = 75/234 (32%), Gaps = 13/234 (5%)
Query: 246 FGRQGHGAGGERGGAAVEFRARVHCH--RGRAGGQGGDFAVQGPR---GRRHGGQGGGEQ 300
FG+ G +G G E R+R + G Q + G R G G G G+
Sbjct: 518 FGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQS 577
Query: 301 TAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRA-------GGCRRGGGRRCGHVRVGVR 353
T + G + G G H + G G + G+ + G R
Sbjct: 578 TGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSR 637
Query: 354 EQASERGHGQALGGQDVLLEV-EGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQ 412
+ + HG + G G GQ + SG+ G G +G +
Sbjct: 638 QTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHG 697
Query: 413 EGTHASGRHAGEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGG 466
G+ S + G+ G+ +G + + + + G + GQ G
Sbjct: 698 FGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSG 751
Score = 32.7 bits (73), Expect = 0.98
Identities = 47/202 (23%), Positives = 65/202 (32%), Gaps = 25/202 (12%)
Query: 246 FGRQGHGAGGERGGAAVEFRARVHCHRGRAGG--QGGDFAVQGPRGRRHGGQ-GGGEQTA 302
FG+ G G+G G E R+ + + G Q + G R GQ G G +
Sbjct: 593 FGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQS 652
Query: 303 AVRDRHRDGVGAVAQPRAH--GVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG 360
++ G G + H G G H + R G G G + +
Sbjct: 653 TGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHES----RSGHSSYGQHGFGSSQSSGYGQ 708
Query: 361 HGQALG------------GQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPR 408
HG + G GQ G G G SG G G ++ G
Sbjct: 709 HGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQS 768
Query: 409 NRGQEGTHASGRHAGEG-APHG 429
+ GQ H+SG G HG
Sbjct: 769 SYGQ---HSSGSSQSSGYGQHG 787
Score = 30.4 bits (67), Expect = 4.9
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 21/200 (10%)
Query: 246 FGRQGHGAGGERG-GAAVEFRARVHC---HRGRAG----GQGGDFAVQGPRGRRHGGQGG 297
FG+ G G+G G G V + H R+G GQ G + Q +HG G
Sbjct: 655 FGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSG 714
Query: 298 GEQTAAVRDRHRDGVGAVAQPRAHGVQIEE--GVAVHRAGGCRRGG----GRRCGHVRVG 351
QT+ +H G + HG + G H +G + G R G G
Sbjct: 715 --QTSGF-GQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYG 771
Query: 352 VREQASER--GHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRN 409
S + G+GQ Q G G G SG G G +G G +
Sbjct: 772 QHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSS 831
Query: 410 RGQEGTHASGRHAGEGAPHG 429
G H S H HG
Sbjct: 832 GF--GQHESRSHQSSYGQHG 849
>gi|239750846 PREDICTED: hypothetical protein [Homo sapiens]
Length = 463
Score = 50.1 bits (118), Expect = 6e-06
Identities = 82/269 (30%), Positives = 99/269 (36%), Gaps = 63/269 (23%)
Query: 293 GGQGGGEQ-------TAAVRDRHRDGVGAVAQPRAHGVQ--------IEEGVAVHRAGGC 337
G GGG Q + V R R GVG+ H VQ G AGGC
Sbjct: 4 GEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGC 63
Query: 338 RRGGGRRCGHVRVGVREQAS-------ERGHGQALGGQDVLLEVEGQGGR---GRPGQSL 387
RG G G VREQ +RGHG G L G GG+ R Q L
Sbjct: 64 LRGRGAERGR---RVREQGGDGRWQRRQRGHGGRRG-----LNGHGDGGQRLARRVAQRL 115
Query: 388 RRSGRG------HGRGIQARDTGGGP-------RNRGQEGTHASGR--------HAGEGA 426
+R G HG G D GG R G+ G H GEG
Sbjct: 116 QRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQ 175
Query: 427 PHGKLAGVQEERVPVEELLARQARGEAEARQ-----GALGQVRGGRVRLHRERREGLLAR 481
P L +++ + E +L +ARG A Q G L QVR R R E + GLL +
Sbjct: 176 PPRHLVFPRDDVLDGEGVL--EARGLRHAAQVVGGGGHLWQVR-ARGRQRAEPQLGLLLQ 232
Query: 482 ERARLFHL-GRRCALANRAPALLRAQAAS 509
R+ L GR+ AL Q A+
Sbjct: 233 VLRRVGWLAGRQVVGLKHLEALAAPQEAA 261
Score = 37.4 bits (85), Expect = 0.040
Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 30/154 (19%)
Query: 249 QGHGAGGER----GGAAVE---FRARVHCHRGRAGGQGGDFAVQ-------GPRGRRHGG 294
QG G GER GGAA+ R R R QGGD Q G RG G
Sbjct: 42 QGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHG 101
Query: 295 QGGGEQTAAVRDR-HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVR 353
GG V R R VGAV R HG + G V AGG HV
Sbjct: 102 DGGQRLARRVAQRLQRHAVGAVVATR-HG---DGGGRVDHAGGAI--------HVWPAGA 149
Query: 354 EQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 387
++A+ HG L G+ V GG G+P + L
Sbjct: 150 QRAA---HGSQLVGERVGSGHRLHGGEGQPPRHL 180
Score = 34.7 bits (78), Expect = 0.26
Identities = 40/132 (30%), Positives = 50/132 (37%), Gaps = 26/132 (19%)
Query: 247 GRQGHGAGGERGGAAVEFRARVHC-------HRGRAGGQ----GGDFAV--QGPRGRRHG 293
G GHG GG+R V R + H G GG+ GG V G + HG
Sbjct: 96 GLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHG 155
Query: 294 GQGGGEQTAAVRDRHRDGVGAVAQPRAHGV----QIEEGVAVHRAGGCRR-----GGGRR 344
Q GE+ + H G QP H V + +G V A G R GGG
Sbjct: 156 SQLVGERVGSGHRLH----GGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGH 211
Query: 345 CGHVRVGVREQA 356
VR R++A
Sbjct: 212 LWQVRARGRQRA 223
>gi|239750574 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1297
Score = 50.1 bits (118), Expect = 6e-06
Identities = 99/351 (28%), Positives = 124/351 (35%), Gaps = 67/351 (19%)
Query: 212 RGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGH----GAGGERGGAAVEFRAR 267
RGR AG +AA + G +F++ G GH G G+ G + +
Sbjct: 698 RGRGAGRA----EAARAAREGGPHQG--VFIQRGRGGLGHRPLPGWRGQGVGPLAQPSVQ 751
Query: 268 VHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAV----RDRHRDGVGAVAQPRAHGV 323
V R G QGP G E TAA R R RDG+G VA A G
Sbjct: 752 VLGRVPRDPAVGAATVAQGPVH----GHVPVELTAAAAVSGRGRLRDGLGRVASVAAEGA 807
Query: 324 QIEEGVAV----HRAG--GCRRGGGRRCGHVRVGV----REQASERGHGQALGGQDVLLE 373
Q+ AV H AG G RGGG G G Q R + +G + V
Sbjct: 808 QVAWAGAVLVQGHEAGVAGGARGGGAAAGGPLAGAVVQRMRQRRVRAGRRRVGARAV--A 865
Query: 374 VEGQGGRGRPGQSLR-RSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLA 432
G+ G G G R R G GHG + Q RH A
Sbjct: 866 AAGRQGAGAGGGGRRVRHGHGHGAAVL------------QRAPCRQQRHLAPAAAAAAAQ 913
Query: 433 GVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLG-- 490
GV R A+G A R GA +G HR G +R RA + G
Sbjct: 914 GV------------RAAQGRAH-RPGA----QGAPSHRHRPGARGRRSRRRAAVALAGGA 956
Query: 491 --RRCALANR--APALLRAQAASAGRDGGGAMAPQMRLGPQGGERDAGLGR 537
R AL R + A+AA R GG Q+ + + G+ D GR
Sbjct: 957 HPARAALGRRRGGGQAVGARAAHQARLAGG-QVDQVVVAARAGDADGVRGR 1006
Score = 48.1 bits (113), Expect = 2e-05
Identities = 90/308 (29%), Positives = 107/308 (34%), Gaps = 54/308 (17%)
Query: 247 GRQGHGAGG-ERGGAAVEFRARVHCHRGRAGGQGGDFAVQ-----GPRGRR------HGG 294
GR+G AGG ERGG R R RGR G V G G R H G
Sbjct: 360 GRRGRAAGGQERGGRG---RRRQQGRRGRRQAGPGLAKVDVDVLAGALGLRWQWVLVHAG 416
Query: 295 QGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCR----RGGGRRCGHVRV 350
Q G R HR A RA + G +R G R G GR G R
Sbjct: 417 QAGQPLQGQARGPHRPAALAQEALRAAAAR-PHGRRHYRVRGLRGAGPEGAGRLAGPWR- 474
Query: 351 GVREQA---SERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGP 407
G+R Q + HG A + VL+ V G G G G+G A G
Sbjct: 475 GLRLQTLLLQDAPHGGA--HEHVLVAVPATGVGGLVGA---------GQGAVA--AAGNA 521
Query: 408 RNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPV-EELLARQARGEAEARQGA-----LG 461
R G G G GA ++AG E VPV ++L G+ A LG
Sbjct: 522 PERLPAGVQGCGEEVGRGARGDRVAGGHVEVVPVGQQLAICMLHGQLGTAPHAHVPTVLG 581
Query: 462 QVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMAPQ 521
GGR GL+A R RR R P R + G GG +
Sbjct: 582 GALGGRA--------GLVAAPARRECPARRRGGCWPRRP---RRRHGGGGGGGGPGLQDL 630
Query: 522 MRLGPQGG 529
+ G GG
Sbjct: 631 LGGGHAGG 638
Score = 47.4 bits (111), Expect = 4e-05
Identities = 110/401 (27%), Positives = 132/401 (32%), Gaps = 75/401 (18%)
Query: 254 GGERGGAA--VEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDG 311
GG GG A V AR C R GG + PR RRHGG GGG +D
Sbjct: 581 GGALGGRAGLVAAPARRECPARRRGGCWP----RRPR-RRHGGGGGGGGPGL-----QDL 630
Query: 312 VGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVL 371
+G AHG + A A R G R GHV V + A+ G L VL
Sbjct: 631 LGGGHAGGAHGHVVVAPAAA--APTAREGRAGRHGHVAVVCPQVAAGAPVGADLDVSVVL 688
Query: 372 -LEVEGQGGRGR------PGQSLRRSGRGHGRGIQARDTGG-------GPRNRG-----Q 412
+ V G GRGR ++ R G G IQ R GG G R +G Q
Sbjct: 689 WVGVVGHLGRGRGAGRAEAARAAREGGPHQGVFIQ-RGRGGLGHRPLPGWRGQGVGPLAQ 747
Query: 413 EGTHASGR----------HAGEGAPHGKL------AGVQEERVPVEELLARQARGEAEAR 456
GR +G HG + A R + + L R A AE
Sbjct: 748 PSVQVLGRVPRDPAVGAATVAQGPVHGHVPVELTAAAAVSGRGRLRDGLGRVASVAAEGA 807
Query: 457 Q--------------GALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPAL 502
Q G G RGG ++ R R R GRR A
Sbjct: 808 QVAWAGAVLVQGHEAGVAGGARGGGAAAGGPLAGAVVQRMRQRRVRAGRRRVGAR----- 862
Query: 503 LRAQAASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRER---RRAV 559
A+AGR G GA R+ G A L R L A R A
Sbjct: 863 ---AVAAAGRQGAGAGGGGRRVRHGHGHGAAVLQRAPCRQQRHLAPAAAAAAAQGVRAAQ 919
Query: 560 GRQRQRGEERRLVTQHRAHGEVRRPKREERAGSRLAPEPCR 600
GR + G + +HR RR +R P R
Sbjct: 920 GRAHRPGAQGAPSHRHRPGARGRRSRRRAAVALAGGAHPAR 960
Score = 41.2 bits (95), Expect = 0.003
Identities = 48/150 (32%), Positives = 58/150 (38%), Gaps = 15/150 (10%)
Query: 237 GGRLFLRAEFGRQGHGAGGERGGAAVEFRA-RVHCHRGRAGGQGGDFAVQGPRGRRHGGQ 295
G + RA +Q H A AA RA + HR A G G RGRR +
Sbjct: 888 GAAVLQRAPCRQQRHLAPAAAAAAAQGVRAAQGRAHRPGAQGAPSHRHRPGARGRRSRRR 947
Query: 296 ------GGGEQTAAVRDRHRDGVGAVAQPRAH-----GVQIEEGVAVHRAGGCRRGGGRR 344
GG A R R G AV AH G Q+++ V RAG GRR
Sbjct: 948 AAVALAGGAHPARAALGRRRGGGQAVGARAAHQARLAGGQVDQVVVAARAGDADGVRGRR 1007
Query: 345 CGHVRVGVR---EQASERGHGQALGGQDVL 371
+ + R E+ ER HG G DVL
Sbjct: 1008 PRRLALTARPELEELLERLHGLQDGLVDVL 1037
Score = 32.7 bits (73), Expect = 0.98
Identities = 63/212 (29%), Positives = 80/212 (37%), Gaps = 19/212 (8%)
Query: 208 GTGLRGRAAGPVRLGFQA---ANQPLDALQFAGGR-LFLRAEFGRQGHGAGGERGGAAVE 263
G GR+ P R QA P AL+ GR L L GR + + A
Sbjct: 183 GLSAHGRSTAP-RTTDQAPGLTRGPRPALRCQRGRRLQLSWGGGRLVAPSRADTHAALAA 241
Query: 264 FRARVHCHRGRAGGQGGDFAVQGPRG-RRHGGQGGGEQTAAVRDRH-RDGVGAVAQPRAH 321
F R H GR G +G G RR GG+G G AA R D +GA R
Sbjct: 242 FPERDIFHGGRVVALGVVGEGRGHGGDRRGGGEGLGTVAAAAPLRVCADDLGAAVGVRGL 301
Query: 322 GVQIEEGV----AVHRAGGCRRGGGRRCGHVRV----GVREQASERGHGQALGGQDVLLE 373
++EG+ +H A RR GH G R++ RG G V+
Sbjct: 302 A-GLQEGLDSRHLLHEAQPLH--ARRRAGHAGSFWLRGGRDRL-RRGGGHTKSHLGVVTI 357
Query: 374 VEGQGGRGRPGQSLRRSGRGHGRGIQARDTGG 405
V G+ GR GQ GR +G + R G
Sbjct: 358 VPGRRGRAAGGQERGGRGRRRQQGRRGRRQAG 389
>gi|239745208 PREDICTED: hypothetical protein XP_002343389 [Homo
sapiens]
Length = 463
Score = 50.1 bits (118), Expect = 6e-06
Identities = 82/269 (30%), Positives = 99/269 (36%), Gaps = 63/269 (23%)
Query: 293 GGQGGGEQ-------TAAVRDRHRDGVGAVAQPRAHGVQ--------IEEGVAVHRAGGC 337
G GGG Q + V R R GVG+ H VQ G AGGC
Sbjct: 4 GEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGC 63
Query: 338 RRGGGRRCGHVRVGVREQAS-------ERGHGQALGGQDVLLEVEGQGGR---GRPGQSL 387
RG G G VREQ +RGHG G L G GG+ R Q L
Sbjct: 64 LRGRGAERGR---RVREQGGDGRWQRRQRGHGGRRG-----LNGHGDGGQRLARRVAQRL 115
Query: 388 RRSGRG------HGRGIQARDTGGGP-------RNRGQEGTHASGR--------HAGEGA 426
+R G HG G D GG R G+ G H GEG
Sbjct: 116 QRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQ 175
Query: 427 PHGKLAGVQEERVPVEELLARQARGEAEARQ-----GALGQVRGGRVRLHRERREGLLAR 481
P L +++ + E +L +ARG A Q G L QVR R R E + GLL +
Sbjct: 176 PPRHLVFPRDDVLDGEGVL--EARGLRHAAQVVGGGGHLWQVR-ARGRQRAEPQLGLLLQ 232
Query: 482 ERARLFHL-GRRCALANRAPALLRAQAAS 509
R+ L GR+ AL Q A+
Sbjct: 233 VLRRVGWLAGRQVVGLKHLEALAAPQEAA 261
Score = 37.4 bits (85), Expect = 0.040
Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 30/154 (19%)
Query: 249 QGHGAGGER----GGAAVE---FRARVHCHRGRAGGQGGDFAVQ-------GPRGRRHGG 294
QG G GER GGAA+ R R R QGGD Q G RG G
Sbjct: 42 QGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHG 101
Query: 295 QGGGEQTAAVRDR-HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVR 353
GG V R R VGAV R HG + G V AGG HV
Sbjct: 102 DGGQRLARRVAQRLQRHAVGAVVATR-HG---DGGGRVDHAGGAI--------HVWPAGA 149
Query: 354 EQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 387
++A+ HG L G+ V GG G+P + L
Sbjct: 150 QRAA---HGSQLVGERVGSGHRLHGGEGQPPRHL 180
Score = 34.7 bits (78), Expect = 0.26
Identities = 40/132 (30%), Positives = 50/132 (37%), Gaps = 26/132 (19%)
Query: 247 GRQGHGAGGERGGAAVEFRARVHC-------HRGRAGGQ----GGDFAV--QGPRGRRHG 293
G GHG GG+R V R + H G GG+ GG V G + HG
Sbjct: 96 GLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHG 155
Query: 294 GQGGGEQTAAVRDRHRDGVGAVAQPRAHGV----QIEEGVAVHRAGGCRR-----GGGRR 344
Q GE+ + H G QP H V + +G V A G R GGG
Sbjct: 156 SQLVGERVGSGHRLH----GGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGH 211
Query: 345 CGHVRVGVREQA 356
VR R++A
Sbjct: 212 LWQVRARGRQRA 223
>gi|169205732 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1297
Score = 50.1 bits (118), Expect = 6e-06
Identities = 99/351 (28%), Positives = 124/351 (35%), Gaps = 67/351 (19%)
Query: 212 RGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGH----GAGGERGGAAVEFRAR 267
RGR AG +AA + G +F++ G GH G G+ G + +
Sbjct: 698 RGRGAGRA----EAARAAREGGPHQG--VFIQRGRGGLGHRPLPGWRGQGVGPLAQPSVQ 751
Query: 268 VHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAV----RDRHRDGVGAVAQPRAHGV 323
V R G QGP G E TAA R R RDG+G VA A G
Sbjct: 752 VLGRVPRDPAVGAATVAQGPVH----GHVPVELTAAAAVSGRGRLRDGLGRVASVAAEGA 807
Query: 324 QIEEGVAV----HRAG--GCRRGGGRRCGHVRVGV----REQASERGHGQALGGQDVLLE 373
Q+ AV H AG G RGGG G G Q R + +G + V
Sbjct: 808 QVAWAGAVLVQGHEAGVAGGARGGGAAAGGPLAGAVVQRMRQRRVRAGRRRVGARAV--A 865
Query: 374 VEGQGGRGRPGQSLR-RSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLA 432
G+ G G G R R G GHG + Q RH A
Sbjct: 866 AAGRQGAGAGGGGRRVRHGHGHGAAVL------------QRAPCRQQRHLAPAAAAAAAQ 913
Query: 433 GVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLG-- 490
GV R A+G A R GA +G HR G +R RA + G
Sbjct: 914 GV------------RAAQGRAH-RPGA----QGAPSHRHRPGARGRRSRRRAAVALAGGA 956
Query: 491 --RRCALANR--APALLRAQAASAGRDGGGAMAPQMRLGPQGGERDAGLGR 537
R AL R + A+AA R GG Q+ + + G+ D GR
Sbjct: 957 HPARAALGRRRGGGQAVGARAAHQARLAGG-QVDQVVVAARAGDADGVRGR 1006
Score = 48.1 bits (113), Expect = 2e-05
Identities = 90/308 (29%), Positives = 107/308 (34%), Gaps = 54/308 (17%)
Query: 247 GRQGHGAGG-ERGGAAVEFRARVHCHRGRAGGQGGDFAVQ-----GPRGRR------HGG 294
GR+G AGG ERGG R R RGR G V G G R H G
Sbjct: 360 GRRGRAAGGQERGGRG---RRRQQGRRGRRQAGPGLAKVDVDVLAGALGLRWQWVLVHAG 416
Query: 295 QGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCR----RGGGRRCGHVRV 350
Q G R HR A RA + G +R G R G GR G R
Sbjct: 417 QAGQPLQGQARGPHRPAALAQEALRAAAAR-PHGRRHYRVRGLRGAGPEGAGRLAGPWR- 474
Query: 351 GVREQA---SERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGP 407
G+R Q + HG A + VL+ V G G G G+G A G
Sbjct: 475 GLRLQTLLLQDAPHGGA--HEHVLVAVPATGVGGLVGA---------GQGAVA--AAGNA 521
Query: 408 RNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPV-EELLARQARGEAEARQGA-----LG 461
R G G G GA ++AG E VPV ++L G+ A LG
Sbjct: 522 PERLPAGVQGCGEEVGRGARGDRVAGGHVEVVPVGQQLAICMLHGQLGTAPHAHVPTVLG 581
Query: 462 QVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMAPQ 521
GGR GL+A R RR R P R + G GG +
Sbjct: 582 GALGGRA--------GLVAAPARRECPARRRGGCWPRRP---RRRHGGGGGGGGPGLQDL 630
Query: 522 MRLGPQGG 529
+ G GG
Sbjct: 631 LGGGHAGG 638
Score = 47.4 bits (111), Expect = 4e-05
Identities = 110/401 (27%), Positives = 132/401 (32%), Gaps = 75/401 (18%)
Query: 254 GGERGGAA--VEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDG 311
GG GG A V AR C R GG + PR RRHGG GGG +D
Sbjct: 581 GGALGGRAGLVAAPARRECPARRRGGCWP----RRPR-RRHGGGGGGGGPGL-----QDL 630
Query: 312 VGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVL 371
+G AHG + A A R G R GHV V + A+ G L VL
Sbjct: 631 LGGGHAGGAHGHVVVAPAAA--APTAREGRAGRHGHVAVVCPQVAAGAPVGADLDVSVVL 688
Query: 372 -LEVEGQGGRGR------PGQSLRRSGRGHGRGIQARDTGG-------GPRNRG-----Q 412
+ V G GRGR ++ R G G IQ R GG G R +G Q
Sbjct: 689 WVGVVGHLGRGRGAGRAEAARAAREGGPHQGVFIQ-RGRGGLGHRPLPGWRGQGVGPLAQ 747
Query: 413 EGTHASGR----------HAGEGAPHGKL------AGVQEERVPVEELLARQARGEAEAR 456
GR +G HG + A R + + L R A AE
Sbjct: 748 PSVQVLGRVPRDPAVGAATVAQGPVHGHVPVELTAAAAVSGRGRLRDGLGRVASVAAEGA 807
Query: 457 Q--------------GALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPAL 502
Q G G RGG ++ R R R GRR A
Sbjct: 808 QVAWAGAVLVQGHEAGVAGGARGGGAAAGGPLAGAVVQRMRQRRVRAGRRRVGAR----- 862
Query: 503 LRAQAASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRER---RRAV 559
A+AGR G GA R+ G A L R L A R A
Sbjct: 863 ---AVAAAGRQGAGAGGGGRRVRHGHGHGAAVLQRAPCRQQRHLAPAAAAAAAQGVRAAQ 919
Query: 560 GRQRQRGEERRLVTQHRAHGEVRRPKREERAGSRLAPEPCR 600
GR + G + +HR RR +R P R
Sbjct: 920 GRAHRPGAQGAPSHRHRPGARGRRSRRRAAVALAGGAHPAR 960
Score = 41.2 bits (95), Expect = 0.003
Identities = 48/150 (32%), Positives = 58/150 (38%), Gaps = 15/150 (10%)
Query: 237 GGRLFLRAEFGRQGHGAGGERGGAAVEFRA-RVHCHRGRAGGQGGDFAVQGPRGRRHGGQ 295
G + RA +Q H A AA RA + HR A G G RGRR +
Sbjct: 888 GAAVLQRAPCRQQRHLAPAAAAAAAQGVRAAQGRAHRPGAQGAPSHRHRPGARGRRSRRR 947
Query: 296 ------GGGEQTAAVRDRHRDGVGAVAQPRAH-----GVQIEEGVAVHRAGGCRRGGGRR 344
GG A R R G AV AH G Q+++ V RAG GRR
Sbjct: 948 AAVALAGGAHPARAALGRRRGGGQAVGARAAHQARLAGGQVDQVVVAARAGDADGVRGRR 1007
Query: 345 CGHVRVGVR---EQASERGHGQALGGQDVL 371
+ + R E+ ER HG G DVL
Sbjct: 1008 PRRLALTARPELEELLERLHGLQDGLVDVL 1037
Score = 32.7 bits (73), Expect = 0.98
Identities = 63/212 (29%), Positives = 80/212 (37%), Gaps = 19/212 (8%)
Query: 208 GTGLRGRAAGPVRLGFQA---ANQPLDALQFAGGR-LFLRAEFGRQGHGAGGERGGAAVE 263
G GR+ P R QA P AL+ GR L L GR + + A
Sbjct: 183 GLSAHGRSTAP-RTTDQAPGLTRGPRPALRCQRGRRLQLSWGGGRLVAPSRADTHAALAA 241
Query: 264 FRARVHCHRGRAGGQGGDFAVQGPRG-RRHGGQGGGEQTAAVRDRH-RDGVGAVAQPRAH 321
F R H GR G +G G RR GG+G G AA R D +GA R
Sbjct: 242 FPERDIFHGGRVVALGVVGEGRGHGGDRRGGGEGLGTVAAAAPLRVCADDLGAAVGVRGL 301
Query: 322 GVQIEEGV----AVHRAGGCRRGGGRRCGHVRV----GVREQASERGHGQALGGQDVLLE 373
++EG+ +H A RR GH G R++ RG G V+
Sbjct: 302 A-GLQEGLDSRHLLHEAQPLH--ARRRAGHAGSFWLRGGRDRL-RRGGGHTKSHLGVVTI 357
Query: 374 VEGQGGRGRPGQSLRRSGRGHGRGIQARDTGG 405
V G+ GR GQ GR +G + R G
Sbjct: 358 VPGRRGRAAGGQERGGRGRRRQQGRRGRRQAG 389
>gi|239756319 PREDICTED: hypothetical protein [Homo sapiens]
Length = 463
Score = 49.7 bits (117), Expect = 8e-06
Identities = 78/257 (30%), Positives = 96/257 (37%), Gaps = 56/257 (21%)
Query: 298 GEQTAAVRDRHRDGVGAVAQPRAHGVQ--------IEEGVAVHRAGGCRRGGGRRCGHVR 349
G+ + V R R GVG+ H VQ G AGGC RG G G
Sbjct: 16 GKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGR-- 73
Query: 350 VGVREQAS-------ERGHGQALGGQDVLLEVEGQGGR---GRPGQSLRRSGRG------ 393
VREQ +RGHG G L G GG+ R Q L+R G
Sbjct: 74 -RVREQGGDGRWQRRQRGHGGRRG-----LNGHGDGGQRLARRVAQRLQRHAVGAVVATR 127
Query: 394 HGRGIQARDTGGGP-------RNRGQEGTHASGR--------HAGEGAPHGKLAGVQEER 438
HG G D GG R G+ G H GEG P L +++
Sbjct: 128 HGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDV 187
Query: 439 VPVEELLARQARGEAEARQ-----GALGQVRGGRVRLHRERREGLLARERARLFHL-GRR 492
+ E +L +ARG A Q G L QVR R R E + GLL + R+ L GR+
Sbjct: 188 LDGEGVL--EARGLRHAAQVVGGGGHLWQVR-ARGRQRAEPQLGLLLQVLRRVGWLAGRQ 244
Query: 493 CALANRAPALLRAQAAS 509
AL Q A+
Sbjct: 245 VVGLKHLEALAAPQEAA 261
Score = 37.4 bits (85), Expect = 0.040
Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 30/154 (19%)
Query: 249 QGHGAGGER----GGAAVE---FRARVHCHRGRAGGQGGDFAVQ-------GPRGRRHGG 294
QG G GER GGAA+ R R R QGGD Q G RG G
Sbjct: 42 QGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHG 101
Query: 295 QGGGEQTAAVRDR-HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVR 353
GG V R R VGAV R HG + G V AGG HV
Sbjct: 102 DGGQRLARRVAQRLQRHAVGAVVATR-HG---DGGGRVDHAGGAI--------HVWPAGA 149
Query: 354 EQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 387
++A+ HG L G+ V GG G+P + L
Sbjct: 150 QRAA---HGSQLVGERVGSGHRLHGGEGQPPRHL 180
Score = 37.0 bits (84), Expect = 0.052
Identities = 47/144 (32%), Positives = 53/144 (36%), Gaps = 23/144 (15%)
Query: 326 EEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQ 385
E G A G RGG CG V R G G+ G GG G
Sbjct: 14 EPGKASEVVGRRTRGGVGSCGSVH-------RHRVQGGGRAGE----RFAGGGGAALAGG 62
Query: 386 SLRRSGRGHGRGIQARDTGGGPR-NRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEEL 444
LR GRG RG + R+ GG R R Q G H G +G G Q V +
Sbjct: 63 CLR--GRGAERGRRVREQGGDGRWQRRQRG------HGGRRGLNGHGDGGQRLARRVAQR 114
Query: 445 LARQARGEAEARQGALGQVRGGRV 468
L R A G A + G GGRV
Sbjct: 115 LQRHAVGAVVATRHGDG---GGRV 135
Score = 34.7 bits (78), Expect = 0.26
Identities = 40/132 (30%), Positives = 50/132 (37%), Gaps = 26/132 (19%)
Query: 247 GRQGHGAGGERGGAAVEFRARVHC-------HRGRAGGQ----GGDFAV--QGPRGRRHG 293
G GHG GG+R V R + H G GG+ GG V G + HG
Sbjct: 96 GLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHG 155
Query: 294 GQGGGEQTAAVRDRHRDGVGAVAQPRAHGV----QIEEGVAVHRAGGCRR-----GGGRR 344
Q GE+ + H G QP H V + +G V A G R GGG
Sbjct: 156 SQLVGERVGSGHRLH----GGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGH 211
Query: 345 CGHVRVGVREQA 356
VR R++A
Sbjct: 212 LWQVRARGRQRA 223
>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
sapiens]
Length = 600
Score = 49.3 bits (116), Expect = 1e-05
Identities = 59/197 (29%), Positives = 69/197 (35%), Gaps = 38/197 (19%)
Query: 248 RQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGD---FAVQGPRGRRHGGQGGGEQTAAV 304
R G G G GG GR GG+GGD F +GPRG R GGG
Sbjct: 415 RGGPGGPGGPGGPM-----------GRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRA 463
Query: 305 RDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRR-----GGGRRCGHVRVGVREQASER 359
D G Q A + + A G GG R G
Sbjct: 464 GDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG------------- 510
Query: 360 GHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRN-----RGQEG 414
G G GG+ L++ G GG R G+ R G GRG+ GGG R G
Sbjct: 511 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLM 570
Query: 415 THASGRHAGEGAPHGKL 431
GR G G P GK+
Sbjct: 571 EQMGGRRGGRGGP-GKM 586
>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
sapiens]
Length = 655
Score = 49.3 bits (116), Expect = 1e-05
Identities = 59/197 (29%), Positives = 69/197 (35%), Gaps = 38/197 (19%)
Query: 248 RQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGD---FAVQGPRGRRHGGQGGGEQTAAV 304
R G G G GG GR GG+GGD F +GPRG R GGG
Sbjct: 470 RGGPGGPGGPGGPM-----------GRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRA 518
Query: 305 RDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRR-----GGGRRCGHVRVGVREQASER 359
D G Q A + + A G GG R G
Sbjct: 519 GDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG------------- 565
Query: 360 GHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRN-----RGQEG 414
G G GG+ L++ G GG R G+ R G GRG+ GGG R G
Sbjct: 566 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLM 625
Query: 415 THASGRHAGEGAPHGKL 431
GR G G P GK+
Sbjct: 626 EQMGGRRGGRGGP-GKM 641
>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
sapiens]
Length = 661
Score = 49.3 bits (116), Expect = 1e-05
Identities = 59/197 (29%), Positives = 69/197 (35%), Gaps = 38/197 (19%)
Query: 248 RQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGD---FAVQGPRGRRHGGQGGGEQTAAV 304
R G G G GG GR GG+GGD F +GPRG R GGG
Sbjct: 476 RGGPGGPGGPGGPM-----------GRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRA 524
Query: 305 RDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRR-----GGGRRCGHVRVGVREQASER 359
D G Q A + + A G GG R G
Sbjct: 525 GDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG------------- 571
Query: 360 GHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRN-----RGQEG 414
G G GG+ L++ G GG R G+ R G GRG+ GGG R G
Sbjct: 572 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLM 631
Query: 415 THASGRHAGEGAPHGKL 431
GR G G P GK+
Sbjct: 632 EQMGGRRGGRGGP-GKM 647
>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
sapiens]
Length = 656
Score = 49.3 bits (116), Expect = 1e-05
Identities = 59/197 (29%), Positives = 69/197 (35%), Gaps = 38/197 (19%)
Query: 248 RQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGD---FAVQGPRGRRHGGQGGGEQTAAV 304
R G G G GG GR GG+GGD F +GPRG R GGG
Sbjct: 471 RGGPGGPGGPGGPM-----------GRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRA 519
Query: 305 RDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRR-----GGGRRCGHVRVGVREQASER 359
D G Q A + + A G GG R G
Sbjct: 520 GDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG------------- 566
Query: 360 GHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRN-----RGQEG 414
G G GG+ L++ G GG R G+ R G GRG+ GGG R G
Sbjct: 567 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLM 626
Query: 415 THASGRHAGEGAPHGKL 431
GR G G P GK+
Sbjct: 627 EQMGGRRGGRGGP-GKM 642
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 48.9 bits (115), Expect = 1e-05
Identities = 76/229 (33%), Positives = 88/229 (38%), Gaps = 43/229 (18%)
Query: 203 DSDVSGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFG--RQGHGAGGER--G 258
DS SG RGR G R G++ GGR R +G R G G GG+R G
Sbjct: 383 DSRPSGGDFRGRGYGGER-GYRGR----------GGRGGDRGGYGGDRSGGGYGGDRSSG 431
Query: 259 GAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQP 318
G R+ GG GGD + G G R GG GG DR G G
Sbjct: 432 GGYSGDRS--------GGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDR---GGGYGGDR 480
Query: 319 RAHGVQIEEGVAVHRAG-GCRRG--GGRRCGH--VRVGVREQASERGHGQALGGQDVLLE 373
+G G R G G RG GG R G+ R G S G+G GG
Sbjct: 481 GGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGG----- 535
Query: 374 VEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGG-PRNRGQEGTHASGRH 421
G GG G RSG G+G D GGG +RG G GR+
Sbjct: 536 -SGYGGDRSGGYGGDRSGGGYG-----GDRGGGYGGDRGGYGGKMGGRN 578
Score = 48.1 bits (113), Expect = 2e-05
Identities = 67/207 (32%), Positives = 85/207 (41%), Gaps = 34/207 (16%)
Query: 249 QGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAA---VR 305
+G G GGERG +RGR GG+GGD G G R GG GG++++
Sbjct: 392 RGRGYGGERG------------YRGR-GGRGGDRGGYG--GDRSGGGYGGDRSSGGGYSG 436
Query: 306 DRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCR--RGGGR---RCGHVRVGVREQASERG 360
DR G G +G G R GG RGGG R G+ +RG
Sbjct: 437 DRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRG 496
Query: 361 -HGQALGGQDVLLEVEGQGG-RGRPGQSLRRSG----RGHGRGIQARDTGG--GPRNRGQ 412
+G GG + G GG RG G R G RG G G +GG G R+ G
Sbjct: 497 GYGGDRGGYGG--DRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGG 554
Query: 413 EGTHASGRHAGE-GAPHGKLAGVQEER 438
G G + G+ G GK+ G + R
Sbjct: 555 YGGDRGGGYGGDRGGYGGKMGGRNDYR 581
Score = 36.2 bits (82), Expect = 0.089
Identities = 41/156 (26%), Positives = 53/156 (33%), Gaps = 12/156 (7%)
Query: 282 FAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGG 341
FA + P R GG GGG + R R G G + + RR
Sbjct: 314 FATRRPEFMRGGGSGGGRRGRG-GYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNS 372
Query: 342 GRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRG--RPGQSLRRSGRGH----- 394
+C R + G+ GG+ G+GGRG R G RSG G+
Sbjct: 373 CNQCNEPRPEDSRPSGGDFRGRGYGGE---RGYRGRGGRGGDRGGYGGDRSGGGYGGDRS 429
Query: 395 -GRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHG 429
G G +GGG G + R G G G
Sbjct: 430 SGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRG 465
Score = 36.2 bits (82), Expect = 0.089
Identities = 74/284 (26%), Positives = 85/284 (29%), Gaps = 92/284 (32%)
Query: 243 RAEFGRQGHGAGGERGGAA----------------------------VEFRARVHCH--- 271
R EF R G GG RG + F R C+
Sbjct: 318 RPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCN 377
Query: 272 --------------RGRA----------GGQGGDFAVQGPRGRRHGGQGGGEQTAA---V 304
RGR GG+GGD G G R GG GG++++
Sbjct: 378 EPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYG--GDRSGGGYGGDRSSGGGYS 435
Query: 305 RDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQA 364
DR G G +G G R GG GG R G+ G+G
Sbjct: 436 GDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGG--YGGDRGGGY-------GGDRGGYGGD 486
Query: 365 LGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTG--GGPRNRGQEGTHASGRHA 422
GG G GG R G R G G RG D G GG R+RG G G
Sbjct: 487 RGG--------GYGG-DRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG 537
Query: 423 GEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGG 466
G G G R G R G G RGG
Sbjct: 538 YGGDRSGGYGG------------DRSGGGYGGDRGGGYGGDRGG 569
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 48.9 bits (115), Expect = 1e-05
Identities = 76/229 (33%), Positives = 88/229 (38%), Gaps = 43/229 (18%)
Query: 203 DSDVSGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFG--RQGHGAGGER--G 258
DS SG RGR G R G++ GGR R +G R G G GG+R G
Sbjct: 386 DSRPSGGDFRGRGYGGER-GYRGR----------GGRGGDRGGYGGDRSGGGYGGDRSSG 434
Query: 259 GAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQP 318
G R+ GG GGD + G G R GG GG DR G G
Sbjct: 435 GGYSGDRS--------GGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDR---GGGYGGDR 483
Query: 319 RAHGVQIEEGVAVHRAG-GCRRG--GGRRCGH--VRVGVREQASERGHGQALGGQDVLLE 373
+G G R G G RG GG R G+ R G S G+G GG
Sbjct: 484 GGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGG----- 538
Query: 374 VEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGG-PRNRGQEGTHASGRH 421
G GG G RSG G+G D GGG +RG G GR+
Sbjct: 539 -SGYGGDRSGGYGGDRSGGGYG-----GDRGGGYGGDRGGYGGKMGGRN 581
Score = 48.1 bits (113), Expect = 2e-05
Identities = 67/207 (32%), Positives = 85/207 (41%), Gaps = 34/207 (16%)
Query: 249 QGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAA---VR 305
+G G GGERG +RGR GG+GGD G G R GG GG++++
Sbjct: 395 RGRGYGGERG------------YRGR-GGRGGDRGGYG--GDRSGGGYGGDRSSGGGYSG 439
Query: 306 DRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCR--RGGGR---RCGHVRVGVREQASERG 360
DR G G +G G R GG RGGG R G+ +RG
Sbjct: 440 DRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRG 499
Query: 361 -HGQALGGQDVLLEVEGQGG-RGRPGQSLRRSG----RGHGRGIQARDTGG--GPRNRGQ 412
+G GG + G GG RG G R G RG G G +GG G R+ G
Sbjct: 500 GYGGDRGGYGG--DRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGG 557
Query: 413 EGTHASGRHAGE-GAPHGKLAGVQEER 438
G G + G+ G GK+ G + R
Sbjct: 558 YGGDRGGGYGGDRGGYGGKMGGRNDYR 584
Score = 36.2 bits (82), Expect = 0.089
Identities = 41/156 (26%), Positives = 53/156 (33%), Gaps = 12/156 (7%)
Query: 282 FAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGG 341
FA + P R GG GGG + R R G G + + RR
Sbjct: 317 FATRRPEFMRGGGSGGGRRGRG-GYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNS 375
Query: 342 GRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRG--RPGQSLRRSGRGH----- 394
+C R + G+ GG+ G+GGRG R G RSG G+
Sbjct: 376 CNQCNEPRPEDSRPSGGDFRGRGYGGE---RGYRGRGGRGGDRGGYGGDRSGGGYGGDRS 432
Query: 395 -GRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHG 429
G G +GGG G + R G G G
Sbjct: 433 SGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRG 468
Score = 36.2 bits (82), Expect = 0.089
Identities = 74/284 (26%), Positives = 85/284 (29%), Gaps = 92/284 (32%)
Query: 243 RAEFGRQGHGAGGERGGAA----------------------------VEFRARVHCH--- 271
R EF R G GG RG + F R C+
Sbjct: 321 RPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCN 380
Query: 272 --------------RGRA----------GGQGGDFAVQGPRGRRHGGQGGGEQTAA---V 304
RGR GG+GGD G G R GG GG++++
Sbjct: 381 EPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYG--GDRSGGGYGGDRSSGGGYS 438
Query: 305 RDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQA 364
DR G G +G G R GG GG R G+ G+G
Sbjct: 439 GDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGG--YGGDRGGGY-------GGDRGGYGGD 489
Query: 365 LGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTG--GGPRNRGQEGTHASGRHA 422
GG G GG R G R G G RG D G GG R+RG G G
Sbjct: 490 RGG--------GYGG-DRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG 540
Query: 423 GEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGG 466
G G G R G R G G RGG
Sbjct: 541 YGGDRSGGYGG------------DRSGGGYGGDRGGGYGGDRGG 572
>gi|56699482 hypothetical protein LOC25940 [Homo sapiens]
Length = 518
Score = 48.5 bits (114), Expect = 2e-05
Identities = 55/179 (30%), Positives = 66/179 (36%), Gaps = 17/179 (9%)
Query: 247 GRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRD 306
GR GH GG RGG + H GR GG+G QG G GGG Q RD
Sbjct: 350 GRGGHEQGGGRGGRGG------YDHGGRGGGRGNKH--QGGWTDGGSGGGGGYQDGGYRD 401
Query: 307 RHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALG 366
G + G Q G + G G + G + R Q HG G
Sbjct: 402 SGFQPGGYHGGHSSGGYQ-GGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGH-HGDRGG 459
Query: 367 GQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEG 425
G+ G+GGRG G + G GRG Q GG Q G + H+G G
Sbjct: 460 GRG------GRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGY-QYNHSGFG 511
Score = 43.5 bits (101), Expect = 6e-04
Identities = 60/182 (32%), Positives = 72/182 (39%), Gaps = 28/182 (15%)
Query: 248 RQGHGAGGERGGAAVEFRARVHCHRGRAGG--QGGDFAVQGPRGRRHGGQGGG---EQTA 302
+Q G GG RGG H G GG QGG +G G HGG+GGG +
Sbjct: 331 QQTGGRGGGRGGYE-------HSSYGGRGGHEQGGGRGGRG--GYDHGGRGGGRGNKHQG 381
Query: 303 AVRDRHRDGVGAVAQP--RAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG 360
D G G R G Q H +GG + GG G + +S G
Sbjct: 382 GWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGG-------YGGFQTSSSYTG 434
Query: 361 HGQALGG--QDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHAS 418
G GG QD + G G R G R GRG GRG +A GGG RG + H
Sbjct: 435 SGYQGGGYQQDNRYQDGGHHG-DRGGGRGGRGGRG-GRGGRA-GQGGGWGGRGSQNYHQG 491
Query: 419 GR 420
G+
Sbjct: 492 GQ 493
Score = 32.0 bits (71), Expect = 1.7
Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 9/79 (11%)
Query: 351 GVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNR 410
G ++Q RG G+ GG E GGRG Q R GRG G GGG N+
Sbjct: 328 GPQQQTGGRGGGR--GGY----EHSSYGGRGGHEQGGGRGGRG---GYDHGGRGGGRGNK 378
Query: 411 GQEGTHASGRHAGEGAPHG 429
Q G G G G G
Sbjct: 379 HQGGWTDGGSGGGGGYQDG 397
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 47.8 bits (112), Expect = 3e-05
Identities = 56/219 (25%), Positives = 76/219 (34%), Gaps = 21/219 (9%)
Query: 247 GRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHG----GQGGGEQTA 302
G + G G E G E +G G+ G+ +G G G G+G GE+
Sbjct: 835 GEEEEGEGEEEEGEGEEEEGE---GKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEG 891
Query: 303 AVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHG 362
+G G + + EEG G G G G G E G G
Sbjct: 892 EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEG-EEGEGE--GEEEEGEGEGEDGEGEG 948
Query: 363 QALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEG--THASGR 420
+ G+ E EG+G G+ G G G + G G G+E G
Sbjct: 949 EEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGE--EEEGEGEGEEEEGEEEGEEEGEGE 1006
Query: 421 HAGEGAPHGKLAGVQEERVPVE-ELLARQARGEAEARQG 458
GEG G +EE VE E+ + GE E +G
Sbjct: 1007 EEGEG------EGEEEEEGEVEGEVEGEEGEGEGEEEEG 1039
Score = 35.4 bits (80), Expect = 0.15
Identities = 65/298 (21%), Positives = 94/298 (31%), Gaps = 49/298 (16%)
Query: 210 GLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGG--------ERGGAA 261
G GR G G A D + G + R E R G G +R G
Sbjct: 650 GPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEE 709
Query: 262 VEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAH 321
E + R H+ + + G G+G E+ + ++G G +
Sbjct: 710 QEQKEREQGHQKERNQEMEE------GGEEEHGEGEEEEGDREEEEEKEGEG---KEEGE 760
Query: 322 GVQIE------EGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEV- 374
G ++E EG + G G G E+ RG + GG+ EV
Sbjct: 761 GEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVE 820
Query: 375 -----------EGQG----GRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASG 419
EG+G G G + G G+G + + G G G+EG
Sbjct: 821 EGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEG-EEEGEEGEGEGE 879
Query: 420 RHAGEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREG 477
GEG + G EE + GE E G+ G + E EG
Sbjct: 880 EEEGEGEGEEEGEGEGEE---------EEGEGEGEEEGEGEGEEEEGEGKGEEEGEEG 928
>gi|28875797 small protein rich in arginine and glycine [Homo
sapiens]
Length = 248
Score = 47.4 bits (111), Expect = 4e-05
Identities = 50/132 (37%), Positives = 57/132 (43%), Gaps = 22/132 (16%)
Query: 272 RGRAGGQGGDFAVQG-PRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVA 330
RG GG+G +G PRG GG+ A R R G+ Q G G A
Sbjct: 97 RGAIGGRGLPIIQRGLPRGGLRGGR-------ATRTLLRGGMSLRGQNLLRG-----GRA 144
Query: 331 VHRAGGCRRGGGR-RCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRR 389
V G RRGG R R G R G+ A RG +GG+ G GRGR G R
Sbjct: 145 VAPRMGLRRGGVRGRGGPGRGGLGRGAMGRG---GIGGRG-----RGMIGRGRGGFGGRG 196
Query: 390 SGRGHGRGIQAR 401
GRG GRG AR
Sbjct: 197 RGRGRGRGALAR 208
Score = 39.3 bits (90), Expect = 0.010
Identities = 37/96 (38%), Positives = 40/96 (41%), Gaps = 6/96 (6%)
Query: 336 GCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVL----LEVEGQGGRGRPGQ-SLRRS 390
G RGG R R +R S RG GG+ V L G GRG PG+ L R
Sbjct: 111 GLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGLRRGGVRGRGGPGRGGLGRG 170
Query: 391 GRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGA 426
G G GI R G R RG G GR G GA
Sbjct: 171 AMGRG-GIGGRGRGMIGRGRGGFGGRGRGRGRGRGA 205
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 46.6 bits (109), Expect = 7e-05
Identities = 57/173 (32%), Positives = 65/173 (37%), Gaps = 32/173 (18%)
Query: 271 HRGRAGGQGGDFAVQGP---RGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEE 327
HRGR GG+GG+ P RG R G GGG R G G V H
Sbjct: 704 HRGR-GGRGGNEPPPPPPPFRGARGGRSGGGPPNG----RGGPGGGMVGGG-GHRPHEGP 757
Query: 328 GVAVHRAGGCRR----GGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRP 383
G + + G R GGG GH G G ++GG EG GG G
Sbjct: 758 GGGMGNSSGHRPHEGPGGGMGSGH--------RPHEGPGGSMGGGGGHRPHEGPGG-GIS 808
Query: 384 GQSLRRSGRGHGRGIQARDTGGGPR-------NRGQEGTHASGRHAGEGAPHG 429
G S R G G G+ A GGG R + G G H G G PHG
Sbjct: 809 GGSGHRPHEGPGGGMGA---GGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHG 858
Score = 29.6 bits (65), Expect = 8.3
Identities = 49/173 (28%), Positives = 58/173 (33%), Gaps = 33/173 (19%)
Query: 371 LLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTG-GGPRNRGQEGTHASGRHAGEGAPHG 429
+L G G G G G +G+Q G GGP G H G G P G
Sbjct: 613 MLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPM---------PGPHGGPGGPVG 663
Query: 430 -KLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFH 488
+L G RG G +RGG +R G +H
Sbjct: 664 PRLLGPPPP-----------PRGGDPFWDGPGDPMRGGPMRGGPGPGPGP--------YH 704
Query: 489 LGRRCALANRAPALLRA-QAASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQ 540
GR N P + A GR GGG P R GP GG G RPH+
Sbjct: 705 RGRGGRGGNEPPPPPPPFRGARGGRSGGGP--PNGRGGPGGGMVGGGGHRPHE 755
>gi|239749709 PREDICTED: hypothetical protein [Homo sapiens]
Length = 178
Score = 46.6 bits (109), Expect = 7e-05
Identities = 60/167 (35%), Positives = 72/167 (43%), Gaps = 20/167 (11%)
Query: 360 GHGQA-LGGQDVLLEVEGQGGRGRPGQSLR--RSGRGHGRGIQA---RDTGGGPRNRGQE 413
G G++ LGG V G+G G +R RS R G G +A R GG PR + Q
Sbjct: 10 GRGRSGLGGSGGAPRVRGRGTAVGVGIGVRVWRSRRAEGGGAEAAAARTAGGEPRAQRQA 69
Query: 414 GTHASGRHAGEGAPHGKLAGVQEERVPVEELLARQAR-GEAEARQGALGQVRGGRVRLHR 472
G+ A EG G+ V +VP E L A+ G + QGA Q R H
Sbjct: 70 GSQAD----EEG---GRPERVNHGQVPQGERLRAMAKGGVGKGSQGAERQAS----RPHA 118
Query: 473 ERREGLLARERARLFHLGRRCALA--NRAPALLRAQAASAGRDGGGA 517
E R GL RA RR A A R+P RA AA R GG A
Sbjct: 119 EHRLGLSHLTRAAGAGAARRRAGAARTRSPKGCRAGAARLERAGGPA 165
Score = 35.8 bits (81), Expect = 0.12
Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 3/71 (4%)
Query: 508 ASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERRRAVGRQRQRGE 567
A+A R GG Q + G Q E GRP ++ H ++ QG R R + + +G
Sbjct: 53 AAAARTAGGEPRAQRQAGSQADEEG---GRPERVNHGQVPQGERLRAMAKGGVGKGSQGA 109
Query: 568 ERRLVTQHRAH 578
ER+ H H
Sbjct: 110 ERQASRPHAEH 120
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 45.4 bits (106), Expect = 1e-04
Identities = 71/286 (24%), Positives = 96/286 (33%), Gaps = 69/286 (24%)
Query: 244 AEFGRQG--HGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQT 301
AE RQ H A GG A + R AG + G Q RH G G G+ +
Sbjct: 3592 AESSRQSGTHHAENSSGGQAASSHEQA---RSSAGERHGSHHQQSADSSRHSGIGHGQAS 3648
Query: 302 AAVRDR-HRDGVGAVA-------------------QPRAHGVQIEEGVAVHRAGGCRRGG 341
+AVRD HR G+ A Q H +E AG R G
Sbjct: 3649 SAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSG 3708
Query: 342 G----------RRCGHVRVGV---------REQASERG-HGQALGGQDVLLEVEGQGGRG 381
H R G EQA + H + GQD + G G
Sbjct: 3709 SFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGG 3768
Query: 382 RPG----QSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGR------HAGEGAPHGKL 431
R G QS+ RSG G + GQ G+ ++ R +G+G+ H
Sbjct: 3769 RQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRH--- 3825
Query: 432 AGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREG 477
+G + + +R + Q G+ G R R RR+G
Sbjct: 3826 SGSRHHEASTQADSSRHS-------QSGQGESAGSR----RSRRQG 3860
Score = 45.1 bits (105), Expect = 2e-04
Identities = 87/371 (23%), Positives = 125/371 (33%), Gaps = 87/371 (23%)
Query: 272 RGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDR-HRDGVGAVAQP-RAHGVQIE-EG 328
R AG + G Q RH G G G+ ++AVRD HR G+ A H + +
Sbjct: 2647 RSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQS 2706
Query: 329 VAVHRAGG---------CRRGGGRRCGH-----VRVGVREQA---------SERG----- 360
V+ H G R G GH +V EQ+ S RG
Sbjct: 2707 VSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSR 2766
Query: 361 ---------HGQALGGQDVLLEVEGQGGRGRPG----QSLRRSGRGHGRGIQARDTGGGP 407
H + GQD + G GR G S+ SG G
Sbjct: 2767 HEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSD 2826
Query: 408 RNRGQEGTHASGR------HAGEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALG 461
+RGQ G+ ++ R +G+G+ H +G + ++R + Q G
Sbjct: 2827 ASRGQSGSRSASRTTRNEEQSGDGSRH---SGSRHHEASTHADISRHS-------QAVQG 2876
Query: 462 QVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMAPQ 521
Q G R R RR+G + + + + SA R+ G+ Q
Sbjct: 2877 QSEGSR----RSRRQGSSVSQDSD----------SEGHSEDSERWSGSASRNHHGSAQEQ 2922
Query: 522 MRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERRRAVGRQRQRGEERRLVTQHRAHGEV 581
+R G + R HQ DR G G R++ R Q + + H E
Sbjct: 2923 LRDGSRH-------PRSHQ--EDRAGHGHSADSSRQSGTRHTQTSSGGQAASSH----EQ 2969
Query: 582 RRPKREERAGS 592
R ER GS
Sbjct: 2970 ARSSAGERHGS 2980
Score = 42.7 bits (99), Expect = 0.001
Identities = 76/351 (21%), Positives = 115/351 (32%), Gaps = 25/351 (7%)
Query: 249 QGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRH 308
+GH G RGG + + G +G QG HG G + R+
Sbjct: 1490 RGH-PGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEE 1548
Query: 309 RDGVGA-VAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGG 367
+ G G+ + R H G + H G G + R Q S + G
Sbjct: 1549 QSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTS------RRQGSSVSQDRDSEG 1602
Query: 368 QDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAP 427
E + S R R R ++ E + SG E +
Sbjct: 1603 HSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSS 1662
Query: 428 HGKLAGVQEERVPVEELLARQARGE---AEARQGALGQVRGGRVRLHRERREGLLARERA 484
G+ A QE+ AR + GE + +Q A G R R++ + +
Sbjct: 1663 GGQAASSQEQ--------ARSSPGERHGSRHQQSADSSTDSGTGR----RQDSSVVGDSG 1710
Query: 485 RLFHLGRRCALANRAPALLRAQAASA-GRDGGGAMAPQMRLGPQGGERDAGLGR-PHQLI 542
G + + + Q+ SA G+ G + Q Q GER G +Q+
Sbjct: 1711 NRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVS 1770
Query: 543 HDRLGQGARQRERRRAVGRQRQRGEERRLVTQHRAHGEVRRPKREERAGSR 593
+ A R GRQR R E+ R ++H A E + R SR
Sbjct: 1771 THEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSR 1821
Score = 40.8 bits (94), Expect = 0.004
Identities = 52/194 (26%), Positives = 68/194 (35%), Gaps = 45/194 (23%)
Query: 272 RGRAGGQGGD-FAVQGPRGRRHGGQGGGEQTAAVRDR-HRDGVGAVAQ------------ 317
R AG + G +Q RH G G G+ ++AVRD HR G+ A
Sbjct: 701 RSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQ 760
Query: 318 ------PRAHGVQIEEGVAVHRAGGCRRGGGRRCGHV---------------RVGVR--- 353
H Q + A R+G R G V GVR
Sbjct: 761 SVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGS 820
Query: 354 --EQASERG-HGQALGGQDVLLEVEGQGGRGRPG----QSLRRSGRGHGRGIQARDTGGG 406
EQA + H + GQD + G RGR G QS+ RSG G
Sbjct: 821 HHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRS 880
Query: 407 PRNRGQEGTHASGR 420
+RGQ G+ ++ R
Sbjct: 881 DASRGQSGSRSASR 894
Score = 40.8 bits (94), Expect = 0.004
Identities = 52/192 (27%), Positives = 69/192 (35%), Gaps = 26/192 (13%)
Query: 244 AEFGRQG--HGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQT 301
AE RQ H A GG A + R AG + G Q RH G G G+ +
Sbjct: 2296 AESSRQSGTHHAENSSGGQAASSHEQA---RSSAGERHGSHHQQSADSSRHSGIGHGQAS 2352
Query: 302 AAVRDR-HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG 360
+AVRD HR G+ A + + +V G + G + H Q S RG
Sbjct: 2353 SAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHG---QAGPHQQSH-------QESTRG 2402
Query: 361 HGQALGGQ------DVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEG 414
G+ V + + GR G S GR QARD+ + QEG
Sbjct: 2403 RSAGRSGRSGSFLYQVSTHEQSESAHGRTGTS--TGGRQGSHHKQARDS--SRHSTSQEG 2458
Query: 415 THASGRHAGEGA 426
H G +
Sbjct: 2459 QDTIHGHPGSSS 2470
Score = 40.8 bits (94), Expect = 0.004
Identities = 63/245 (25%), Positives = 86/245 (35%), Gaps = 68/245 (27%)
Query: 248 RQGHGAGGER-------------GGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGG 294
R GHG +R GG A + R G + G Q RH G
Sbjct: 3261 RAGHGHSADRSRQSGTRHAETSSGGQAASSHEQA---RSSPGERHGSRHQQSADSSRHSG 3317
Query: 295 QGGGEQTAAVRD-RHRDGVGAVA-QPRAHGVQIE-EGVAVHRAGGCR----------RGG 341
G+ ++AVRD RH G+ A H + + + V+ H G R G
Sbjct: 3318 IPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSG 3377
Query: 342 GR--RCGH--VRVGVREQASERGHGQ------------------------ALGGQDVLLE 373
GR R G +V EQ SE HG+ + GQD +
Sbjct: 3378 GRSGRSGSFLYQVSTHEQ-SESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRG 3436
Query: 374 VEGQGGRGRPG----QSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGR------HAG 423
G RGR G QS+ RSG G +RGQ G+ ++ R +G
Sbjct: 3437 HPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSG 3496
Query: 424 EGAPH 428
+G+ H
Sbjct: 3497 DGSRH 3501
Score = 39.7 bits (91), Expect = 0.008
Identities = 70/310 (22%), Positives = 97/310 (31%), Gaps = 53/310 (17%)
Query: 271 HRGRAG-GQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGV 329
H RAG G D + Q G RH G Q A+ ++ R G HG + ++
Sbjct: 3258 HEDRAGHGHSADRSRQS--GTRHAETSSGGQAASSHEQARSSPG-----ERHGSRHQQSA 3310
Query: 330 AVHRAGGCRRGGG----RRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQ 385
R G RG R H + + GH + Q V G G G Q
Sbjct: 3311 DSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSV----SGHGQAGPHQQ 3366
Query: 386 SLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELL 445
S + S ARD GG R + H + HG+ R
Sbjct: 3367 SHQES---------ARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQ 3417
Query: 446 ARQARGEAEARQGA------LGQVRGGRVRLHRER---REGLLARERARLFHLGRRCALA 496
AR + + +++G G R GR H E+ R G + GR
Sbjct: 3418 ARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGR----- 3472
Query: 497 NRAPALLRAQAASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERR 556
AS G+ G + + Q R Q G+ G H H R
Sbjct: 3473 ---------SDASRGQSGSRSASRQTRNDEQSGD-----GSRHSWSHHHEASTQADSSRH 3518
Query: 557 RAVGRQRQRG 566
G+ + G
Sbjct: 3519 SQSGQGQSAG 3528
Score = 39.3 bits (90), Expect = 0.010
Identities = 84/366 (22%), Positives = 117/366 (31%), Gaps = 75/366 (20%)
Query: 272 RGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDR-HRDGVGAVAQP-RAHGVQIE-EG 328
R AG + G Q RH G G G+ ++AVRD HR G+ A H + +
Sbjct: 2971 RSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQS 3030
Query: 329 VAVHRAGG---------CRRGGGRRCGH-----VRVGVREQA---------SERG----- 360
V+ H G R G GH +V EQ+ S RG
Sbjct: 3031 VSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSR 3090
Query: 361 ---------HGQALGGQDVLLEVEGQGGRGRPG----QSLRRSGRGHGRGIQARDTGGGP 407
H + GQD + G GR G S+ SG G
Sbjct: 3091 HEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSD 3150
Query: 408 RNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGR 467
+RGQ G+ ++ R G + R A +R Q GQ G R
Sbjct: 3151 ASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHS----QAVQGQSEGSR 3206
Query: 468 VRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMAPQMRLGPQ 527
R RR+G + + + + SA R+ G++ Q R G +
Sbjct: 3207 ----RSRRQGSSVSQDSD----------SEGHSEDSERWSGSASRNHRGSVQEQSRHGSR 3252
Query: 528 GGERDAGLGRPHQLIHDRLGQGARQRERRRAVGRQRQRGEERRLVTQHRAHGEVRRPKRE 587
P DR G G R++ R + + + H E R
Sbjct: 3253 ---------HPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSH----EQARSSPG 3299
Query: 588 ERAGSR 593
ER GSR
Sbjct: 3300 ERHGSR 3305
Score = 37.0 bits (84), Expect = 0.052
Identities = 57/230 (24%), Positives = 77/230 (33%), Gaps = 57/230 (24%)
Query: 251 HGAGGERGGAAVEFRARVHCHRGRAGGQ-GGDFAVQGPRGRRHGGQGGGEQTAAVRDR-H 308
H RG AA R AG + G +Q RH G G G+ ++AVRD H
Sbjct: 1981 HTESSSRGQAASSHEQA----RSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGH 2036
Query: 309 RDGVGAVAQPRAHGVQIEEGVAVHRAG-----------GCRRGGGRRCGH-----VRVGV 352
R G+ A + + +V G R G G +V
Sbjct: 2037 RGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVST 2096
Query: 353 REQASERGHGQAL------------------------GGQDVLLEVEGQGGRGRPG---- 384
EQ SE HGQ+ GQD + G GR G
Sbjct: 2097 HEQ-SESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQE 2155
Query: 385 QSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGR------HAGEGAPH 428
QS+ RSG G +RGQ G+ ++ R +G+G+ H
Sbjct: 2156 QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRH 2205
Score = 34.7 bits (78), Expect = 0.26
Identities = 59/270 (21%), Positives = 87/270 (32%), Gaps = 37/270 (13%)
Query: 249 QGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRH 308
+GH G RGG + G +G QG HG G + R+
Sbjct: 517 RGH-PGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEE 575
Query: 309 RDGVGA-VAQPRAHGVQIEEGVAVHRAGGCRRGGGRRC---------------GHVRVGV 352
+ G G + R H + + H G + G R GH
Sbjct: 576 QSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSE 635
Query: 353 R--EQASERGHGQAL-----GGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGI------- 398
R AS HG A G + E + G G S R+SG H +
Sbjct: 636 RWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAAS 695
Query: 399 ---QARDTGGGPR-NRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLARQARGEAE 454
QAR + G +R Q + S RH+G G HG+ + + ++ E
Sbjct: 696 SHEQARSSAGERHGSRHQLQSADSSRHSGTG--HGQASSAVRDSGHRGSSGSQATDSEGH 753
Query: 455 ARQGALGQVRGGRVRLHRERREGLLARERA 484
+ V G H ++ AR+R+
Sbjct: 754 SEDSDTQSVSGHGQAGHHQQSHQESARDRS 783
Score = 34.7 bits (78), Expect = 0.26
Identities = 48/209 (22%), Positives = 66/209 (31%), Gaps = 20/209 (9%)
Query: 271 HRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVA 330
H+ G G G RH G Q A+ ++ R G HG ++
Sbjct: 2933 HQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAG-----ERHGSHHQQSAD 2987
Query: 331 VHRAGGCRRGGG----RRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQS 386
R G G R GH + + GH + Q V GQ G S
Sbjct: 2988 SSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSV--SAHGQAG------S 3039
Query: 387 LRRSGRGHGRGIQARDTGGGPRNRGQEGTH--ASGRHAGEGAPHGKLAGVQEERVPVEEL 444
++S + RG +G Q TH + H G G + E+
Sbjct: 3040 HQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR 3099
Query: 445 LARQARGEAEARQGALGQVRGGRVRLHRE 473
+ G+ R G G RGGR H E
Sbjct: 3100 HSASQYGQDTIR-GHPGSSRGGRQGYHHE 3127
Score = 34.3 bits (77), Expect = 0.34
Identities = 80/405 (19%), Positives = 116/405 (28%), Gaps = 54/405 (13%)
Query: 238 GRLFLRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQ-- 295
G+ +R G G G +V+ H QG A +G G R +
Sbjct: 3430 GQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQT 3489
Query: 296 ------GGGEQ----------TAAVRDRH-RDGVGAVAQPRAHGVQIEEGVAVHRAGGCR 338
G G + T A RH + G G A PR Q + G
Sbjct: 3490 RNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHS 3549
Query: 339 RGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGI 398
R G R A E+ G + E + G G +S R+SG H
Sbjct: 3550 EDSERWSGSASRNHRGSAQEQSRD---GSRHPTSHHEDRAGHGHSAESSRQSGTHHAENS 3606
Query: 399 ----------QARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLA---------GVQEERV 439
QAR + G + + S RH+G G HG+ + G +
Sbjct: 3607 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIG--HGQASSAVRDSGHRGSSGSQA 3664
Query: 440 PVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHL---------- 489
E + + ++ + G G + R R G R + L+ +
Sbjct: 3665 SDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAH 3724
Query: 490 GRRCALANRAPALLRAQAASAGRDGGGAMAPQMRLGPQGGERDAGLGRPHQLIHDRLGQG 549
GR QA + R G G R G H+ DR G
Sbjct: 3725 GRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHS 3784
Query: 550 ARQRERRRAVGR-QRQRGEERRLVTQHRAHGEVRRPKREERAGSR 593
+ GR G+ E + +GSR
Sbjct: 3785 GSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSR 3829
Score = 33.5 bits (75), Expect = 0.57
Identities = 77/359 (21%), Positives = 106/359 (29%), Gaps = 78/359 (21%)
Query: 254 GGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVG 313
G RGG + G +G QG HG G + R + G G
Sbjct: 1170 GSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDG 1229
Query: 314 AVAQPRAH--GVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVL 371
+ H + + G + G R H V + + H D
Sbjct: 1230 SRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERH------SDDS 1283
Query: 372 LEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHA-----SGRHAGEGA 426
+ G R G S +S G +R G +R G A SG H E +
Sbjct: 1284 ERLSGSASRNHHGSSREQSRDG------SRHPGFHQEDRASHGHSADSSRQSGTHHTESS 1337
Query: 427 PHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERARL 486
HG+ E QAR R G+ Q
Sbjct: 1338 SHGQAVSSHE-----------QARSSPGERHGSRHQ------------------------ 1362
Query: 487 FHLGRRCALANRAPALLRAQAASAGRDGG--GAMAPQMRLGPQGGERDA--------GLG 536
+ A ++R + QA+SA RD G G+ Q+ +G D+ G
Sbjct: 1363 -----QSADSSRHSGIGHRQASSAVRDSGHRGSSGSQV-TNSEGHSEDSDTQSVSAHGQA 1416
Query: 537 RPHQLIH--DRLGQGARQRERRRAVGRQRQRGEERRLVTQHRAHGEVRRPKREERAGSR 593
PHQ H GQ R R+ Q E+ HG+ P R GSR
Sbjct: 1417 GPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQ-----SESTHGQT-APSTGGRQGSR 1469
Score = 32.7 bits (73), Expect = 0.98
Identities = 42/187 (22%), Positives = 63/187 (33%), Gaps = 31/187 (16%)
Query: 265 RARVHCHRGRAGGQGGDFAV----QGPRGRRHGGQGGGEQTAAVRDRHRDGVGA------ 314
+ R RG++G + Q G RH G E ++ VG
Sbjct: 2174 QGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGP 2233
Query: 315 -VAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLE 373
++PR V + H RR G H +EQ+ + G +
Sbjct: 2234 RTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNH-HGSAQEQSRD-------GSRHPRSH 2285
Query: 374 VEGQGGRGRPGQSLRRSGRGHGRGI----------QARDTGGGPRNRGQEGTHASGRHAG 423
E + G G +S R+SG H QAR + G + + S RH+G
Sbjct: 2286 HEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSG 2345
Query: 424 EGAPHGK 430
G HG+
Sbjct: 2346 IG--HGQ 2350
Score = 32.7 bits (73), Expect = 0.98
Identities = 50/217 (23%), Positives = 70/217 (32%), Gaps = 39/217 (17%)
Query: 247 GRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRD 306
G G +GG +G + R G +G QG HG G + R+
Sbjct: 2464 GHPGSSSGGRQGSHYEQLVDR----SGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRN 2519
Query: 307 RHRDGVGA-VAQPRAHGVQIEEGVAVHRAGGCRRGGGRRC---------------GHVRV 350
+ G G+ + R H + H G + G R GH
Sbjct: 2520 DEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSED 2579
Query: 351 GVR--EQASERGHGQAL-----GGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGI----- 398
R AS HG A G + E + G G S R+SG H +
Sbjct: 2580 SERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQA 2639
Query: 399 -----QARDTGGGPRNRGQEGTHASGRHAGEGAPHGK 430
QAR + G + + S RH+G G HG+
Sbjct: 2640 ASSHEQARSSAGERHGSHHQQSADSSRHSGIG--HGQ 2674
Score = 32.0 bits (71), Expect = 1.7
Identities = 42/210 (20%), Positives = 68/210 (32%), Gaps = 16/210 (7%)
Query: 238 GRLFLRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGG 297
G+ +R G G G +V+ H QG A +G G R
Sbjct: 837 GQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR-----S 891
Query: 298 GEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVH-RAGGCRRGGGRRCGHVRVGVREQA 356
+T ++ RDG + R H ++ H +AG + G R V + +
Sbjct: 892 ASRTTRNEEQSRDG-SRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDS 950
Query: 357 SERGH--------GQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPR 408
GH G A + + + G P +S GHG + G P
Sbjct: 951 DSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHP-RSHHEDRAGHGHSADSSRQSGTPH 1009
Query: 409 NRGQEGTHASGRHAGEGAPHGKLAGVQEER 438
G A+ H + G+ G + ++
Sbjct: 1010 AETSSGGQAASSHEQARSSPGERHGSRHQQ 1039
>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
Length = 398
Score = 45.1 bits (105), Expect = 2e-04
Identities = 64/252 (25%), Positives = 88/252 (34%), Gaps = 30/252 (11%)
Query: 216 AGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRA 275
A VR +Q A + +GG ++ G G G G GG + VH + G +
Sbjct: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNP-GGLGTPW---VHGYPGNS 180
Query: 276 GGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAG 335
G G P G+ GG GG + GAVAQP V+ A ++
Sbjct: 181 AGSFGMNPQGAPWGQ--GGNGGPPNFGT------NTQGAVAQPGYGSVR-----ASNQNE 227
Query: 336 GCRR----GGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSG 391
GC G G + G Q+ G G + G G S SG
Sbjct: 228 GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG 287
Query: 392 RGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLARQARG 451
G +R G + G +SG H G G +G G ++ +ARG
Sbjct: 288 GSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP--------GNEARG 339
Query: 452 EAEAR-QGALGQ 462
E+ QG GQ
Sbjct: 340 SGESGIQGFRGQ 351
>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
Length = 416
Score = 45.1 bits (105), Expect = 2e-04
Identities = 64/252 (25%), Positives = 88/252 (34%), Gaps = 30/252 (11%)
Query: 216 AGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRA 275
A VR +Q A + +GG ++ G G G G GG + VH + G +
Sbjct: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNP-GGLGTPW---VHGYPGNS 180
Query: 276 GGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAG 335
G G P G+ GG GG + GAVAQP V+ A ++
Sbjct: 181 AGSFGMNPQGAPWGQ--GGNGGPPNFGT------NTQGAVAQPGYGSVR-----ASNQNE 227
Query: 336 GCRR----GGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSG 391
GC G G + G Q+ G G + G G S SG
Sbjct: 228 GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG 287
Query: 392 RGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLARQARG 451
G +R G + G +SG H G G +G G ++ +ARG
Sbjct: 288 GSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP--------GNEARG 339
Query: 452 EAEAR-QGALGQ 462
E+ QG GQ
Sbjct: 340 SGESGIQGFRGQ 351
>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
Length = 2263
Score = 44.7 bits (104), Expect = 2e-04
Identities = 55/215 (25%), Positives = 77/215 (35%), Gaps = 35/215 (16%)
Query: 238 GRLFLRAEFGRQG----HGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRR-- 291
GR + + G QG G G+RG + RG G G D +++GP G +
Sbjct: 1479 GRKGEKGDEGSQGSPGKRGTPGDRGAKGL---------RGDPGAPGVDSSIEGPTGLKGE 1529
Query: 292 HGGQG-----------GGEQTAAVRDR--HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCR 338
G QG G + A R H G P G +E + + G R
Sbjct: 1530 RGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDG--LEGSLGLKGPQGPR 1587
Query: 339 RGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHG--R 396
G + VG + G G G Q L QG +G PG + G R
Sbjct: 1588 GEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRL---GSQGNKGEPGDLGEKGAVGFPGPR 1644
Query: 397 GIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKL 431
G+Q D G + G++G GE P G++
Sbjct: 1645 GLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEI 1679
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,067,733
Number of Sequences: 37866
Number of extensions: 1684990
Number of successful extensions: 16423
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 560
Number of HSP's that attempted gapping in prelim test: 12578
Number of HSP's gapped (non-prelim): 3534
length of query: 600
length of database: 18,247,518
effective HSP length: 108
effective length of query: 492
effective length of database: 14,157,990
effective search space: 6965731080
effective search space used: 6965731080
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.