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Search of human proteins with 239754474
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239754474 PREDICTED: similar to mucin [Homo sapiens]
(417 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239754474 PREDICTED: similar to mucin [Homo sapiens] 838 0.0
gi|239508698 PREDICTED: similar to mucin [Homo sapiens] 498 e-141
gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo ... 363 e-100
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 88 1e-17
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 77 4e-14
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 76 5e-14
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 71 2e-12
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 71 2e-12
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 71 2e-12
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 66 5e-11
gi|60097902 filaggrin [Homo sapiens] 65 1e-10
gi|57864582 hornerin [Homo sapiens] 63 4e-10
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 63 4e-10
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 62 1e-09
gi|153070260 myristoylated alanine-rich protein kinase C substra... 61 2e-09
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 61 2e-09
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 60 4e-09
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 60 5e-09
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 60 5e-09
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 59 1e-08
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 59 1e-08
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] 59 1e-08
gi|221316599 chromogranin B precursor [Homo sapiens] 57 2e-08
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 57 3e-08
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 57 4e-08
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 57 4e-08
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 57 4e-08
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 57 4e-08
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 57 4e-08
gi|199559779 coiled-coil domain containing 8 [Homo sapiens] 56 5e-08
>gi|239754474 PREDICTED: similar to mucin [Homo sapiens]
Length = 417
Score = 838 bits (2165), Expect = 0.0
Identities = 417/417 (100%), Positives = 417/417 (100%)
Query: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD
Sbjct: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
Query: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ 120
QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ
Sbjct: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ 120
Query: 121 RRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSS 180
RRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSS
Sbjct: 121 RRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSS 180
Query: 181 PSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQR 240
PSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQR
Sbjct: 181 PSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQR 240
Query: 241 AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEE 300
AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEE
Sbjct: 241 AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEE 300
Query: 301 AAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVP 360
AAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVP
Sbjct: 301 AAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVP 360
Query: 361 TSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEEVRKWKKRVDLS 417
TSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEEVRKWKKRVDLS
Sbjct: 361 TSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEEVRKWKKRVDLS 417
>gi|239508698 PREDICTED: similar to mucin [Homo sapiens]
Length = 265
Score = 498 bits (1281), Expect = e-141
Identities = 250/265 (94%), Positives = 251/265 (94%)
Query: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD
Sbjct: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
Query: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ 120
QQGAQDREEEAAAAPAADQQRAQDREEEAAAAP PTSSGHRTEKRK Q QC+PAGGTGQ
Sbjct: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ 120
Query: 121 RRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSS 180
RRGS SSPSADQQ AQDREEEAAAAP PTSRGHRTEKRK QQPQRRPA GTGQRRGS SS
Sbjct: 121 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS 180
Query: 181 PSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQR 240
PSADQQGAQDREEEAAAAP PTSRGHRTEKRK QQPQCRPA GTGQRRGSRSSPSADQQR
Sbjct: 181 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240
Query: 241 AQDREEEAAAAPAPTSRGHRTEKRK 265
AQDREEEAAAAPAPTS GHRTEKRK
Sbjct: 241 AQDREEEAAAAPAPTSSGHRTEKRK 265
Score = 370 bits (951), Expect = e-102
Identities = 195/232 (84%), Positives = 196/232 (84%), Gaps = 18/232 (7%)
Query: 105 RKRLQLQCQPAGGTGQRRGSRSSPSADQQ------------------RAQDREEEAAAAP 146
R + Q QCQPAGGTGQRRGS SSPSADQQ RAQDREEEAAAAP
Sbjct: 34 RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAP 93
Query: 147 VPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGH 206
PTS GHRTEKRK QQPQ RPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGH
Sbjct: 94 APTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGH 153
Query: 207 RTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKP 266
RTEKRKPQQPQ RPA GTGQRRGSRSSPSADQQ AQDREEEAAAAP PTSRGHRTEKRK
Sbjct: 154 RTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKR 213
Query: 267 QQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRK 318
QQPQ RPA GTGQRRGS SPSADQQ AQDREEEAAAAPAPTSSGHRTEKRK
Sbjct: 214 QQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKRK 265
Score = 370 bits (949), Expect = e-102
Identities = 192/232 (82%), Positives = 196/232 (84%), Gaps = 18/232 (7%)
Query: 158 RKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA----------------- 200
R +QQPQ +PAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA
Sbjct: 34 RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAP 93
Query: 201 -PTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGH 259
PTS GHRTEKRKPQQPQCRPAGGTGQRRGS SSPSADQQ AQDREEEAAAAPAPTSRGH
Sbjct: 94 APTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGH 153
Query: 260 RTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKR 319
RTEKRKPQQPQRRPA GTGQRRGS SPSADQQGAQDREEEAAAAP PTS GHRTEKRKR
Sbjct: 154 RTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKR 213
Query: 320 LQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRK 371
Q QC+PA GTGQRRGS S SA+QQ AQDREEEAAAAP PTSSGHRTEKRK
Sbjct: 214 QQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKRK 265
Score = 329 bits (843), Expect = 3e-90
Identities = 177/220 (80%), Positives = 180/220 (81%), Gaps = 22/220 (10%)
Query: 209 EKRKP----QQPQCRPAGGTGQRRGSRSSPSADQQ------------------RAQDREE 246
EK KP QQPQC+PAGGTGQRRGS SSPSADQQ RAQDREE
Sbjct: 28 EKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREE 87
Query: 247 EAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPA 306
EAAAAPAPTS GHRTEKRKPQQPQ RPAGGTGQRRGSG SPSADQQGAQDREEEAAAAPA
Sbjct: 88 EAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA 147
Query: 307 PTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHR 366
PTS GHRTEKRK Q Q +PA GTGQRRGS S SA+QQGAQDREEEAAAAPVPTS GHR
Sbjct: 148 PTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHR 207
Query: 367 TEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEE 406
TEKRK QQPQ RPAAGTGQRRGS SSPSADQQRAQDREEE
Sbjct: 208 TEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEE 247
Score = 239 bits (611), Expect = 3e-63
Identities = 131/191 (68%), Positives = 140/191 (73%), Gaps = 22/191 (11%)
Query: 238 QQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQR----RPAGGTGQRRGSGYSPSADQQG 293
+Q+ QD + + EK KP +PQ+ +PAGGTGQRRGSG SPSADQQG
Sbjct: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG 63
Query: 294 ------------------AQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRG 335
AQDREEEAAAAPAPTSSGHRTEKRK Q QC+PAGGTGQRRG
Sbjct: 64 AQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRG 123
Query: 336 SGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSA 395
SG S SA+QQGAQDREEEAAAAP PTS GHRTEKRKPQQPQRRPAAGTGQRRGS SSPSA
Sbjct: 124 SGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSA 183
Query: 396 DQQRAQDREEE 406
DQQ AQDREEE
Sbjct: 184 DQQGAQDREEE 194
>gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo
sapiens]
Length = 306
Score = 363 bits (933), Expect = e-100
Identities = 184/236 (77%), Positives = 196/236 (83%)
Query: 158 RKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 217
R +QQPQ +PAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ
Sbjct: 34 RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 93
Query: 218 CRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGT 277
RPAGGTGQRRGSRSS SADQQ AQDREEEAAAAPAPTS GHRTEKRKPQQPQ RPA GT
Sbjct: 94 RRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGT 153
Query: 278 GQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSG 337
GQRRGSG SPSADQQ AQDREEEA AAP PTSSGHRTEKRKRLQLQCQPAGGTGQRRGS
Sbjct: 154 GQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSR 213
Query: 338 CSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSP 393
S S G + + ++P + + + QPQRRPA GTGQRRG+ ++P
Sbjct: 214 SSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAP 269
Score = 358 bits (920), Expect = 4e-99
Identities = 205/304 (67%), Positives = 213/304 (70%), Gaps = 57/304 (18%)
Query: 105 RKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQ 164
R + Q QCQPAGGTGQRRGS SSPSADQQ AQDREEEAAAAP PTSRGHRTEKRK QQPQ
Sbjct: 34 RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 93
Query: 165 RRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGT 224
RRPAGGTGQRRGS SS SADQQGAQDREEEAAAAPAPTS GHRTEKRKPQQPQCRPA GT
Sbjct: 94 RRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGT 153
Query: 225 GQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQ---------------- 268
GQRRGS SPSADQQRAQDREEEA AAP PTS GHRTEKRK Q
Sbjct: 154 GQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSR 213
Query: 269 --PQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQP 326
P R+PAGGTGQRRGS SPSADQQ AQDREEEAA Q Q +P
Sbjct: 214 SSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAA------------------QPQRRP 255
Query: 327 AGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRP-AAGTGQ 385
AGGTGQRRG+ AAAPVPT+ G T +R+ P + GTGQ
Sbjct: 256 AGGTGQRRGT------------------AAAPVPTTGG--TGQRRGTAAAPAPTSTGTGQ 295
Query: 386 RRGS 389
RRGS
Sbjct: 296 RRGS 299
Score = 333 bits (854), Expect = 2e-91
Identities = 177/227 (77%), Positives = 184/227 (81%), Gaps = 22/227 (9%)
Query: 209 EKRKP----QQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKR 264
EK KP QQPQC+PAGGTGQRRGS SSPSADQQ AQDREEEAAAAPAPTSRGHRTEKR
Sbjct: 28 EKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKR 87
Query: 265 KPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQC 324
KPQQPQRRPAGGTGQRRGS S SADQQGAQDREEEAAAAPAPTSSGHRTEKRK Q QC
Sbjct: 88 KPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQC 147
Query: 325 QPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQ---------- 374
+PA GTGQRRGSGCS SA+QQ AQDREEEA AAPVPTSSGHRTEKRK Q
Sbjct: 148 RPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTG 207
Query: 375 --------PQRRPAAGTGQRRGSGSSPSADQQRAQDREEEVRKWKKR 413
P R+PA GTGQRRGS SSPSADQQRAQDREEE + ++R
Sbjct: 208 QRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEEAAQPQRR 254
Score = 43.5 bits (101), Expect = 4e-04
Identities = 36/112 (32%), Positives = 44/112 (39%), Gaps = 40/112 (35%)
Query: 13 RKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAA 72
R R S DQ ++ + QPQ +PAGGTGQRRG+ ++P G R
Sbjct: 228 RGSRSSPSADQQRAQDREEEAA---QPQRRPAGGTGQRRGTAAAPVPTTGGTGQR----- 279
Query: 73 AAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGS 124
AAAP PTS+ GTGQRRGS
Sbjct: 280 --------------RGTAAAPAPTST------------------GTGQRRGS 299
>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
Length = 819
Score = 88.2 bits (217), Expect = 1e-17
Identities = 120/451 (26%), Positives = 181/451 (40%), Gaps = 81/451 (17%)
Query: 13 RKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDRE--EE 70
+KLR + ++ ++P + GG G + G +P + G + R ++
Sbjct: 272 KKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQK 331
Query: 71 AAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAG----GTGQRRGSRS 126
A A AA +R +++AA V + R +K + + AG G G ++G R
Sbjct: 332 ATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLRE 391
Query: 127 SPSADQQRAQDR----EEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPS 182
+ R + R A AP RG ++K +R+ P+ + G R G G P
Sbjct: 392 AKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPR 451
Query: 183 ADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQ---- 238
Q A+ + EA A SRG + + R Q A GT R G S S
Sbjct: 452 RRGQKARQKAAEAGAE----SRGDKKQGR-----QKASAAGTKSRGGGLKSHSGKNLWRR 502
Query: 239 -QRAQDREEEAAAAPAPTSRGHRTEKR---------------KPQQPQRRPA-------- 274
Q+A+ E+A AA A SRG + +R K +Q Q+ A
Sbjct: 503 GQKAEAAGEKATAAGAK-SRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGG 561
Query: 275 GGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRR 334
GG Q RG G G + R+ AA A T G K+ Q AG T R
Sbjct: 562 GGNKQSRGGG--------GNKPRQWGQTAAAAKTRGG----GDKQPGWQKAAAGVTKSRS 609
Query: 335 GSGCSSSANQQ----GAQDR-------EEEAAAAPVPTSSGHRTEKRKPQQPQ-RRPAAG 382
G G + Q+ GA+ R +++AAAA ++G + +QP+ ++PAA
Sbjct: 610 GDGGKKAWRQKAAGTGAKSRKKPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAA 669
Query: 383 TGQRRGSGSSPSADQQRAQDREEEVRKWKKR 413
GS SS +A A +E E RK +R
Sbjct: 670 -----GSESSAAA----AVGQEAEARKKPRR 691
Score = 87.0 bits (214), Expect = 3e-17
Identities = 110/463 (23%), Positives = 181/463 (39%), Gaps = 96/463 (20%)
Query: 16 RESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEA--AA 73
+ ++ G + L KP R Q+ A TG ++ + + G+++R A AA
Sbjct: 107 KAAAAGTKSLGGRGRKPRRRGQK-----AAATGSKKPRWRAQKSAAAGSKNRGAGAQKAA 161
Query: 74 APAADQQRAQDREEEAAAAPVPTSSGH-----------------------------RTEK 104
A A + + ++ ++AAAA + SG R +
Sbjct: 162 AAAGVKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGR 221
Query: 105 RKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQ--- 161
RK+ + AGG RRG P ++R Q + + V SRG +K +RQ
Sbjct: 222 RKKHRRPKPAAGGAKSRRGGGKKPQKQRRRGQ-KAATGGKSRVGKSRGGGDKKLRRQGQN 280
Query: 162 ----------------QPQRRPAGGTGQRRGSGSSPSADQQGAQDR---EEEAAAAPAPT 202
+P + GG G + G +P + G + R ++ AA A T
Sbjct: 281 AALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGT 340
Query: 203 SRG-----------------HRTEKRKPQQPQCRPAG----GTGQRRG----SRSSPSAD 237
RG R +KP++ + AG G G ++G R
Sbjct: 341 KRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRK 400
Query: 238 QQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDR 297
+ R Q+ A APA RG ++K + + P+ + G R G G P Q A+ +
Sbjct: 401 KPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQK 460
Query: 298 EEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAA 357
EA A S G + + R++ A GT + RG G S + + + ++ AA
Sbjct: 461 AAEAGA----ESRGDKKQGRQKAS-----AAGT-KSRGGGLKSHSGKNLWRRGQKAEAAG 510
Query: 358 PVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRA 400
T++G ++ RK QP+R+ A G + G S S +Q+A
Sbjct: 511 EKATAAGAKSRGRK--QPRRQKPAVAGAKSRVGGSKSRQRQKA 551
Score = 86.3 bits (212), Expect = 5e-17
Identities = 83/353 (23%), Positives = 147/353 (41%), Gaps = 33/353 (9%)
Query: 63 GAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRR 122
G + R+ AA A + E++AAAA + G + R+R Q + R
Sbjct: 82 GKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRGRKPRRRGQKAAATGSKKPRWR 141
Query: 123 GSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPS 182
+S+ + + R ++ AAAA V + G + +K + R +G +RRG+ S
Sbjct: 142 AQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAGAKSR-SGKKPRRRGAKSRGD 200
Query: 183 ADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQ 242
D++G R+ EA + T G R + R+P+ AGG RRG P ++R Q
Sbjct: 201 EDKKG---RQREAKSRFGKTRGGRRKKHRRPKP----AAGGAKSRRGGGKKPQKQRRRGQ 253
Query: 243 DREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRG---SGYSPSADQQGAQDREE 299
+ + SRG +K + Q AG +RRG +G P+A +G + +
Sbjct: 254 -KAATGGKSRVGKSRGGGDKKLRRQGQNAALAG--AKRRGAATAGEKPAAKGRGGRGPKS 310
Query: 300 EAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPV 359
P G + +R + + A G +RG G A G + R++
Sbjct: 311 LGGQNPRWGRGGKKPRRRGQ---KATKAAAAGTKRGGGGQQKAAVVGVKSRKK------- 360
Query: 360 PTSSGHRTEKRKPQQPQRRPAAGTGQR-RGSGSSPSADQQRAQDREEEVRKWK 411
++R+ ++P+R+ A+ G + RG G + + + + +W+
Sbjct: 361 --------QRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQ 405
Score = 81.6 bits (200), Expect = 1e-15
Identities = 109/452 (24%), Positives = 185/452 (40%), Gaps = 75/452 (16%)
Query: 2 KPRQKEQDTRLRKLRESSEGDQWLENEKTKPL------------RPQQQPQCQPAGGTGQ 49
K RQ+E +R K R G + ++ + KP +PQ+Q + TG
Sbjct: 204 KGRQREAKSRFGKTR----GGRRKKHRRPKPAAGGAKSRRGGGKKPQKQRRRGQKAATGG 259
Query: 50 RRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQ 109
+ G S + + + + AA A A R A A P + G K L
Sbjct: 260 KSRVGKSRGGGDKKLRRQGQNAALAGA-------KRRGAATAGEKPAAKGRGGRGPKSLG 312
Query: 110 LQCQPAGGTG----QRRGSRS--SPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQP 163
Q P G G +RRG ++ + +A +R +++AA V + + ++R+ ++P
Sbjct: 313 GQ-NPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGV---KSRKKQRRRGKKP 368
Query: 164 QRRPAGGTGQR-RGSGSSP---SADQQGA-------QDREEEAAAAPAPTSRGHRTEKRK 212
+R+ A G + RG G A ++G Q+ A APA RG ++K +
Sbjct: 369 RRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPR 428
Query: 213 PQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR 272
+ P+ + G R G P Q+A+ + EA A SRG + + R Q+
Sbjct: 429 RRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGA----ESRGDKKQGR-----QKA 479
Query: 273 PAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQ 332
A GT R G S S + ++ EAA A T++G ++ RK+ + Q G
Sbjct: 480 SAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKA-TAAGAKSRGRKQPRRQKPAVAGAKS 538
Query: 333 RRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKR-------KPQQPQRRPAA---- 381
R G G++ R+ + A A TS G K+ KP+Q + AA
Sbjct: 539 RVG----------GSKSRQRQKAVAAGATSHGGGGNKQSRGGGGNKPRQWGQTAAAAKTR 588
Query: 382 GTGQRRGSGSSPSADQQRAQDREEEVRKWKKR 413
G G ++ +A +++ + + W+++
Sbjct: 589 GGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQK 620
Score = 75.9 bits (185), Expect = 6e-14
Identities = 101/394 (25%), Positives = 163/394 (41%), Gaps = 55/394 (13%)
Query: 40 QCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSG 99
QC A G R G G+ A +AAPA AAA SG
Sbjct: 8 QCNQAAG---RAGPGAPLGAALARTPVELAAESAAPALSA---------AAAGVKILGSG 55
Query: 100 HRTEKR-------KRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDR---EEEAAAAPVPT 149
+ +R K+ +L+ Q G+ +A A++R E++AAAA +
Sbjct: 56 DKKLRRQKAAAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKS 115
Query: 150 SRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDR----EEEAAAAPAPTSRG 205
G + R+R Q A TG ++ + + G+++R ++ AAAA + G
Sbjct: 116 LGGRGRKPRRRGQK----AAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGG 171
Query: 206 HRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRK 265
+ +K + R +G +RRG++S D+ + R+ EA + T G R + R+
Sbjct: 172 EKPQKAAAAGAKSR-SGKKPRRRGAKSRGDEDK---KGRQREAKSRFGKTRGGRRKKHRR 227
Query: 266 PQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQ 325
P + AGG RRG G P Q + R ++AA R K+L+ Q Q
Sbjct: 228 P----KPAAGGAKSRRGGGKKP----QKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQ 279
Query: 326 PAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEK--RKPQQPQRR----- 378
A G +R G +++ + A+ R P S G + + R ++P+RR
Sbjct: 280 NAALAGAKR-RGAATAGEKPAAKGRGGRG-----PKSLGGQNPRWGRGGKKPRRRGQKAT 333
Query: 379 PAAGTGQRRGSGSSPSADQQRAQDREEEVRKWKK 412
AA G +RG G A + R+++ R+ KK
Sbjct: 334 KAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKK 367
Score = 74.3 bits (181), Expect = 2e-13
Identities = 87/378 (23%), Positives = 141/378 (37%), Gaps = 31/378 (8%)
Query: 31 KPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAA 90
KP R + P+ + G R G G P Q A+ + EA A D++ Q R++ +A
Sbjct: 426 KPRR--RGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKK--QGRQKASA 481
Query: 91 AAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTS 150
A G ++ K L + Q A G++ + + S + R Q R ++ A A +
Sbjct: 482 AGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAAGAKS--RGRKQPRRQKPAVAGAKS- 538
Query: 151 RGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEK 210
R K +Q Q+ A G G G+ S G + R+ AA A T G
Sbjct: 539 ---RVGGSKSRQRQKAVAAGATSHGGGGNKQSRGGGGNKPRQWGQTAAAAKTRGGG---- 591
Query: 211 RKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 270
+QP + A G S S D + R++ A + R ++ +
Sbjct: 592 --DKQPGWQKAAA-----GVTKSRSGDGGKKAWRQKAAGTGAKSRKKPWRRGQKDAAAAE 644
Query: 271 RRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGT 330
+ A G R G P + A E AAAA + + +R+R + + GG
Sbjct: 645 KAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPRRRR--AKSRGDGGQ 702
Query: 331 G--------QRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAG 382
QRRG ++ G + + A S G ++ K + G
Sbjct: 703 NAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSGKKAAASKSHGGG 762
Query: 383 TGQRRGSGSSPSADQQRA 400
+RR G + S ++A
Sbjct: 763 GAKRRRGGGAKSRSGEKA 780
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 76.6 bits (187), Expect = 4e-14
Identities = 102/443 (23%), Positives = 174/443 (39%), Gaps = 70/443 (15%)
Query: 16 RESSEGDQWLENE-KTK-PLRPQQQ----PQCQPAGGTGQRRG-SGSSPSAD-------- 60
+E SE D +++ KT+ PLR + + P+ RR SGSSP
Sbjct: 1554 QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPR 1613
Query: 61 -QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTG 119
Q G+ E A AP A +R++ P P S + P
Sbjct: 1614 AQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPE------HPPKSRT 1667
Query: 120 QRRGSRSSPS-ADQQRAQDREEEAAAAPVPT--SRGHRTEKRKRQQPQRRPAGGTGQRRG 176
RRGSRSSP + R R + ++P T +R R + P+ R RR
Sbjct: 1668 ARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRS 1727
Query: 177 -SGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPS 235
S SSP ++ R +A++P +T R+ + P +P G + SRS
Sbjct: 1728 PSVSSPEPAEKSRSSRRRRSASSPRT-----KTTSRRGRSPSPKPRG----LQRSRSRSR 1778
Query: 236 ADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTG----------------- 278
++ R R + + ++ + + R R+ R + RR GG+G
Sbjct: 1779 REKTRTTRRRDRSGSSQSTSRRRQRSRSR--SRVTRRRRGGSGYHSRSPARQESSRTSSR 1836
Query: 279 QRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGC 338
+RRG +P ++ ++ R A + + + T +R R + +RR
Sbjct: 1837 RRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPL-----ISRRRSRSR 1891
Query: 339 SSSANQQGAQD------REEEAAAAPVPTSSGHRTEKRKPQQPQRRPAA--GTGQRRGSG 390
+S +++ ++ R + A+PV S R+ R P +RR + T +RR
Sbjct: 1892 TSPVSRRRSRSRTSVTRRRSRSRASPV---SRRRSRSRTPPVTRRRSRSRTPTTRRRSRS 1948
Query: 391 SSPSADQQRAQDREEEVRKWKKR 413
+P ++R++ R V + + R
Sbjct: 1949 RTPPVTRRRSRSRTPPVTRRRSR 1971
Score = 67.4 bits (163), Expect = 2e-11
Identities = 82/363 (22%), Positives = 132/363 (36%), Gaps = 41/363 (11%)
Query: 49 QRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRL 108
QRRG SP + + +A + R+ R + R R R
Sbjct: 529 QRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRT 588
Query: 109 QLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPA 168
+ + T RR SRS A + R++ R P R RT R++ + R
Sbjct: 589 PARRRSRSRTPTRRRSRSRTPARRGRSRSR--------TPARRRSRTRSPVRRRSRSR-- 638
Query: 169 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRR 228
+R G S + ++G + + P RG R+ R P + R T RR
Sbjct: 639 -SPARRSGRSRSRTPARRG-------RSRSRTPARRG-RSRSRTPARRSGRSRSRTPARR 689
Query: 229 GSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRG-SGYSP 287
G S S +R + R SR + R +R+ T QRR S SP
Sbjct: 690 G--RSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSP 747
Query: 288 SADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGT----------GQRRGSG 337
+ R + ++P R++ + RL L+ +G + +R SG
Sbjct: 748 EMKKSRISSRRSRSLSSP-------RSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSG 800
Query: 338 CSSSANQQGAQDREEEAAAAPVP--TSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSA 395
S + R ++++P P S + P + +GT R+GS +SP A
Sbjct: 801 SSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQA 860
Query: 396 DQQ 398
++Q
Sbjct: 861 NEQ 863
Score = 61.6 bits (148), Expect = 1e-09
Identities = 94/458 (20%), Positives = 165/458 (36%), Gaps = 78/458 (17%)
Query: 14 KLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAA 73
K R + G + KTK P + RR S SSP ++ R +A+
Sbjct: 1664 KSRTARRGSRSSPEPKTKSRTPPR------------RRSSRSSPELTRKARLSRRSRSAS 1711
Query: 74 APAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSA--- 130
+ + R R + + P + R+R P T RRG SP
Sbjct: 1712 SSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSAS-SPRTKTTSRRGRSPSPKPRGL 1770
Query: 131 DQQRAQDREEEA--------AAAPVPTSRGHRTEKRKRQQPQRRPAGGTG---------- 172
+ R++ R E+ + + TSR R R R + RR GG+G
Sbjct: 1771 QRSRSRSRREKTRTTRRRDRSGSSQSTSR-RRQRSRSRSRVTRRRRGGSGYHSRSPARQE 1829
Query: 173 -------QRRGSGSSPSADQQGAQDREEEA----AAAPAPTSRGHRTEKRKPQQPQCRPA 221
+RRG +P ++ ++ R A + + A + R+ R P + R
Sbjct: 1830 SSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSR 1889
Query: 222 GGTG--QRRGSRSSPSADQQRAQDR------EEEAAAAPAPTSRGHRTEKRKPQQPQRRP 273
T RR SRS S ++R++ R + P T R R+ ++ R
Sbjct: 1890 SRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSR 1949
Query: 274 AGGTGQRRGSGYSPSADQQGAQDR-----EEEAAAAPAPTS---SGHRTEKRKRLQLQCQ 325
+RR +P ++ ++ R + + +P + S RT R + + +
Sbjct: 1950 TPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSR 2009
Query: 326 PAGGTGQRRGSGCSSSANQQGAQ-----DREEEAAAAPVP-----------TSSGHRTEK 369
+ T +R S + ++ R+ + +P+ T+ G R+
Sbjct: 2010 TSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLT 2069
Query: 370 RKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEEV 407
R P +RR A+G+ R ++P A + + R V
Sbjct: 2070 RSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPV 2107
Score = 61.2 bits (147), Expect = 2e-09
Identities = 90/385 (23%), Positives = 142/385 (36%), Gaps = 58/385 (15%)
Query: 43 PAGGTGQRRGSGSSPSADQQGAQDRE----EEAAAAPAAD-QQRAQDREEEAAAAPVPTS 97
PA G RRG G +P ++ + E A P++ + + +D++E++A P P+
Sbjct: 298 PASG---RRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSP 354
Query: 98 SGHRT--EKRKRLQLQCQPAGGTGQRRGSRS------SPSADQQRAQDREEEAAAAPVPT 149
T E L + GG+ Q + +P ++ +DR + +P
Sbjct: 355 ERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQ 414
Query: 150 SRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQG-AQDREEEAAAAPAPTSRGHRT 208
S + P +P T R + SSP + + A E +++P +R H
Sbjct: 415 SSSSESSP-----PSPQP---TKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGR 466
Query: 209 EKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQ 268
KR T RR RS A +R + R PT RGH + R PQ
Sbjct: 467 AKRDKSHSH------TPSRRMGRSRSPATAKRGRSRSR------TPTKRGH-SRSRSPQW 513
Query: 269 PQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAG 328
+ R A QR G SP Q R + S T++R R +
Sbjct: 514 RRSRSA----QRWGRSRSP-------QRRGRSRSPQRPGWSRSRNTQRRGRSR------- 555
Query: 329 GTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRG 388
RRG S S +G A + + R R +RR + T RRG
Sbjct: 556 --SARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRG 613
Query: 389 SGSSPSADQQRAQDREEEVRKWKKR 413
S + ++R++ R R+ + R
Sbjct: 614 RSRSRTPARRRSRTRSPVRRRSRSR 638
Score = 58.5 bits (140), Expect = 1e-08
Identities = 83/415 (20%), Positives = 144/415 (34%), Gaps = 55/415 (13%)
Query: 51 RGSGSSPSADQQGAQDR----EEEAAAAPAADQ-QRAQDREEEAAAAPVPTSSGHRTEKR 105
R SG S S A ++ ++ ++P D R RE ++A+ G
Sbjct: 1377 RSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS 1436
Query: 106 KRLQLQCQPAGGTGQRRGSRSSPSADQQRAQD-------REEEAAAAPVPTSRGHRTEKR 158
+R + P G SR S S +D E ++P P + R
Sbjct: 1437 RRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPR 1496
Query: 159 KRQQ-----------PQRRPAGGT-------------GQRRGSGSSPSADQQGAQDREEE 194
R PQR +G GQR SGSS D + + +E
Sbjct: 1497 SRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQER 1556
Query: 195 AAAAPAPTSRGH-RTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPA 253
+ + +P S+ RT R+ + P + R R S S +D+ A A +
Sbjct: 1557 SESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQS 1616
Query: 254 PTSRGHRTEKRKPQQ-PQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAA-------P 305
+ + P+ P+R +G + + RG S+ + + + ++ A P
Sbjct: 1617 GSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSP 1676
Query: 306 APTSSG----HRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPT 361
P + R R +L + R S + ++ + R + ++P P
Sbjct: 1677 EPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPA 1736
Query: 362 SSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSP---SADQQRAQDREEEVRKWKKR 413
+ +R+ P T RRG SP + R++ R E+ R ++R
Sbjct: 1737 EKSRSSRRRRSAS---SPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRR 1788
Score = 54.3 bits (129), Expect = 2e-07
Identities = 96/451 (21%), Positives = 162/451 (35%), Gaps = 90/451 (19%)
Query: 26 ENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDR 85
E + L ++ + + A G GSS D Q R A PA + +
Sbjct: 120 ETHQLAELNEKKNERLRAAFGISDSYVDGSS--FDPQ----RRAREAKQPAPEPPKPYSL 173
Query: 86 EEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAA 145
E++++ PT + +K+K + + + +R+ +SS + + ++ +
Sbjct: 174 VRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERK--KSSKKKKHRSESESKKRKHRS 231
Query: 146 PVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAA------- 198
P P S+ +K++++ PA + + S S+ SA +AAA
Sbjct: 232 PTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTAL 291
Query: 199 ----PAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGS-------RSSPSADQQRAQDREEE 247
P+P S G R E P P + QR S SSP D+ + D++E+
Sbjct: 292 AGRSPSPAS-GRRGE---GDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDK--DKKEK 345
Query: 248 AAAAPAPTSRGHRTEKRKP-----------------------QQPQRRPAGGTGQR-RGS 283
+A P+P+ T P Q+P P+ + R R
Sbjct: 346 SATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSP 405
Query: 284 GYSPSADQQGAQDREEEAAAAPAPTS-SGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSA 342
SP Q + E + +P PT S H + + + PA G+ + S +S
Sbjct: 406 PKSPEKLPQSSS--SESSPPSPQPTKVSRHASSSPE--SPKPAPAPGSHREISSSPTSKN 461
Query: 343 NQQGAQDREEEAAAAP---------------------VPTSSGHRTEKRKPQQPQRRPAA 381
G R++ + P PT GH + R PQ + R A
Sbjct: 462 RSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGH-SRSRSPQWRRSRSA- 519
Query: 382 GTGQRRGSGSSPSADQQRAQDREEEVRKWKK 412
QR G SP Q+R + R + W +
Sbjct: 520 ---QRWGRSRSP---QRRGRSRSPQRPGWSR 544
Score = 52.0 bits (123), Expect = 1e-06
Identities = 81/406 (19%), Positives = 148/406 (36%), Gaps = 58/406 (14%)
Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
P ++ TR R S + +++ P ++ + + T RRG S + ++
Sbjct: 620 PARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSR--TPARRGRSRSRTPARR 677
Query: 63 GAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKR----LQLQCQPAGGT 118
+ R A + R R + + V H ++R + + T
Sbjct: 678 SGRSRSRTPARR-GRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRT 736
Query: 119 GQRRG-SRSSPSADQQRAQDREEEAAAAPVPTSRGHRT-----------EKRKRQQPQRR 166
QRR S SSP + R R + ++P ++ + K+K Q P RR
Sbjct: 737 SQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRR 796
Query: 167 PAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRK--PQQPQCRPAGGT 224
G+ Q + +P R ++++P P + ++ P + GT
Sbjct: 797 SRSGSSQPKAKSRTPP--------RRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGT 848
Query: 225 GQRRGSRSSPSADQQRAQDREEEA-AAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGS 283
R+GS +SP A++Q + ++P P + K + P R G+ R
Sbjct: 849 PPRQGSITSPQANEQSVTPQRRSCFESSPDP--------ELKSRTPSRHSCSGSSPPRVK 900
Query: 284 GYSP---SADQQGAQDREEEAAAAPAPTS-SGHRTEKRKRLQLQCQPAGGTGQRRGSGCS 339
+P S + + + +A +P S SG + R+ + P RR S
Sbjct: 901 SSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTP------RRSRSVS 954
Query: 340 SSANQQGAQDREEEAAAAPVPTSSGHRT--EKRKPQQPQRRPAAGT 383
+N E+ P + SG + K KP+ P R+ +G+
Sbjct: 955 PCSN--------VESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGS 992
Score = 45.8 bits (107), Expect = 7e-05
Identities = 46/240 (19%), Positives = 82/240 (34%), Gaps = 21/240 (8%)
Query: 31 KPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAA 90
+P + ++ + + S SS S+ G+ + E ++ P E
Sbjct: 2525 QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQP-------EVALK 2577
Query: 91 AAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTS 150
P PT + + R +P +RR S SS S+ + ++++ +S
Sbjct: 2578 RVPSPTPAPKEAVREGRPP---EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2634
Query: 151 RGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRT-- 208
+ PA Q +SP G +R + P + R R+
Sbjct: 2635 SSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG--ERRSRSPRKPIDSLRDSRSLS 2692
Query: 209 ----EKRKPQ-QPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEK 263
E+R+P QP R + RGSR D + + +P P HR+ +
Sbjct: 2693 YSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMR--HRSSR 2750
Score = 42.7 bits (99), Expect = 6e-04
Identities = 68/374 (18%), Positives = 129/374 (34%), Gaps = 39/374 (10%)
Query: 32 PLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAA 91
PL + + + P+ + R S +PS + Q ++ PA DQ R+
Sbjct: 2400 PLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQ-APSQSLLPPAQDQPRS--------- 2449
Query: 92 APVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSR 151
PVP++ +++ + L Q P G+ + + + A VP S
Sbjct: 2450 -PVPSAF---SDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSD 2505
Query: 152 -GHRTEKRKRQQPQRRPA-GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTE 209
G QQP A +RR S SS S+ + ++++ + +S
Sbjct: 2506 VGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEG 2565
Query: 210 KRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQP 269
P QP+ A R AP R R + P +
Sbjct: 2566 SSLPVQPEV----------------------ALKRVPSPTPAPKEAVREGRPPEPTPAKR 2603
Query: 270 QRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGG 329
+RR + + S S S+ + ++++ + +SS + + Q P
Sbjct: 2604 KRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPA 2663
Query: 330 TGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGS 389
+ ++ G S + + D ++ + R + + Q+ ++ G RRG
Sbjct: 2664 SPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQ 2723
Query: 390 -GSSPSADQQRAQD 402
G S S +R ++
Sbjct: 2724 RGDSRSPSHKRRRE 2737
Score = 41.6 bits (96), Expect = 0.001
Identities = 52/275 (18%), Positives = 98/275 (35%), Gaps = 32/275 (11%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHR 101
+P TG ++ S A Q A++R ++++ ++ + +++ SSG
Sbjct: 2508 EPPASTGAQQPSAL---AALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS-----SSGSS 2559
Query: 102 TEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQ 161
+ + L QP +R +P+ + + R E P P R R+
Sbjct: 2560 SSDSEGSSLPVQPE--VALKRVPSPTPAPKEAVREGRPPE----PTPAKRKRRSSSSSSS 2613
Query: 162 QPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPA 221
+ + S SS S+ + ++++P+P G + KP P+ P
Sbjct: 2614 SSSSSSSSSSSS--SSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALP-KPASPKKPPP 2670
Query: 222 GGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRR 281
G +RR D R + + + +P R +R QP R + R
Sbjct: 2671 G---ERRSRSPRKPIDSLR-----DSRSLSYSPVER-----RRPSPQPSPRDQQSSSSER 2717
Query: 282 GSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEK 316
GS D + + +P P HR+ +
Sbjct: 2718 GSRRGQRGDSRSPSHKRRRETPSPRPMR--HRSSR 2750
Score = 39.3 bits (90), Expect = 0.007
Identities = 92/454 (20%), Positives = 152/454 (33%), Gaps = 76/454 (16%)
Query: 2 KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQ 61
+ R + TR R +S + +T P+ ++ P T +RR +P +
Sbjct: 1899 RSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTP---TTRRRSRSRTPPVTR 1955
Query: 62 QGAQDREEEAAAAPAADQQRAQDR-------EEEAAAAPVPTS-SGHRTEKRKRLQLQCQ 113
+ ++ R P ++R++ R + +PV S RT R + + +
Sbjct: 1956 RRSRSR------TPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSR 2009
Query: 114 PAGGTGQRRGSRSSPSADQQRAQ-----DREEEAAAAPVP-----------TSRGHRTEK 157
+ T +R SR+ P+ ++ R+ + +P+ T+RG R+
Sbjct: 2010 TSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLT 2069
Query: 158 RKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 217
R +RR A G+ R ++P A + + R A + S R +
Sbjct: 2070 RSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDR 2129
Query: 218 CRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGH-RTEKRKPQQPQRRPAGG 276
CR G SR+ S QQ + P P H RT + R
Sbjct: 2130 CRSPGMLEPLGSSRTPMSVLQQAGGSMMD----GPGPRIPDHQRTSVPENHAQSRIALAL 2185
Query: 277 TGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGS 336
T G+ P + AP P S L+ PA R +
Sbjct: 2186 TAISLGTARPPPSMSAAGLAARMSQVPAPVPLMS-----------LRTAPAANLASRIPA 2234
Query: 337 GCSSSANQQGAQ-----------DREEEAAAA---------PVPTSSGHRTEKRKPQQP- 375
+++ N A+ D AAAA V S+ + + R P P
Sbjct: 2235 ASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPA 2294
Query: 376 -----QRRPAA-GTGQRRGSGSSPSADQQRAQDR 403
R PAA GSG+ P+A + R
Sbjct: 2295 VNLAGARTPAALAALSLTGSGTPPTAANYPSSSR 2328
Score = 37.4 bits (85), Expect = 0.025
Identities = 81/448 (18%), Positives = 149/448 (33%), Gaps = 72/448 (16%)
Query: 2 KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQ 61
+P+ K + R SS + ++ P + GT R+GS +SP A++
Sbjct: 803 QPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANE 862
Query: 62 QGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQR 121
Q + + + +++ + + P T R +
Sbjct: 863 QSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPR---------------Q 907
Query: 122 RGSRSSPSADQQRA----QDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQR--- 174
SRSS + +A + R +++P P+ RT R+ + P R
Sbjct: 908 SPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVS--PCSNVESRLLP 965
Query: 175 ----RGSGSSPSADQQGAQDREE-----------EAAAAPAPTSRGHRT----EKRKPQQ 215
GS S + + R+ +A P P+ G ++ EK K
Sbjct: 966 RYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSL 1025
Query: 216 PQCRPAGGTGQRRGSRSSPSADQQ-----------RAQDREEEAAAAPAPTSRGHRTEKR 264
Q P G G +SS + ++Q + + +P R +E
Sbjct: 1026 VQSCP-GSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESP 1084
Query: 265 KPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQC 324
Q + G R S + A + + E +A+P S + R +
Sbjct: 1085 SLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSS 1144
Query: 325 QPAGGTGQRRGSGC--SSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAG 382
P + G ++ + ++ A +E+A A+P + +K P Q RP +
Sbjct: 1145 YPTVDSNSLLGQSRLETAESKEKMALPPQEDATASP-----PRQKDKFSPFPVQDRPESS 1199
Query: 383 ----------TGQRRGSGSSPSADQQRA 400
+R G+GSSP +Q +
Sbjct: 1200 LVFKDTLRTPPRERSGAGSSPETKEQNS 1227
Score = 34.7 bits (78), Expect = 0.16
Identities = 86/403 (21%), Positives = 139/403 (34%), Gaps = 72/403 (17%)
Query: 52 GSGSSPSADQQGAQDREEEAAA---------APAADQQRAQDREEEAAAAPV-------- 94
GSG+ P+A + R +A A A A AA AP
Sbjct: 2313 GSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMA 2372
Query: 95 PTSSG-HRTEKRKRLQLQCQPAGGTG----QRRGSRSSPSADQQRAQDREEEAAAAPVPT 149
P SG + T R L + +G T R SR+ PSA Q E AP P+
Sbjct: 2373 PALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSER----APSPS 2428
Query: 150 SRGHRTEKRKRQQPQRR------PAGGTGQRRG--SGSSPSADQQ----GAQDREEEAA- 196
SR + + P + P+ + Q R + ++P A Q GA +A
Sbjct: 2429 SRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAG 2488
Query: 197 ------AAPAP----TSRGHRTEKRKPQQPQCRPA-GGTGQRRGSRSSPSADQQRAQDRE 245
+ PAP + G QQP A +RR S SS S+ +
Sbjct: 2489 DHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSS 2548
Query: 246 EEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAP 305
++++ + +S P QP+ +R +P+ + + R E P
Sbjct: 2549 SSSSSSSSGSSSSDSEGSSLPVQPE------VALKRVPSPTPAPKEAVREGRPPE----P 2598
Query: 306 APTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGH 365
P KRKR + + + S SSS++ + ++++ +SS
Sbjct: 2599 TPA-------KRKR-----RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646
Query: 366 RTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEEVR 408
+ PQ P + ++ G S ++ D + R
Sbjct: 2647 SSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSR 2689
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 76.3 bits (186), Expect = 5e-14
Identities = 101/423 (23%), Positives = 148/423 (34%), Gaps = 83/423 (19%)
Query: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSS--PSADQ 61
R + RK R S + EK K +++P + G R SGSS PS
Sbjct: 211 RDRSDSGSRRKRRHRSRSSKCKRKEKNKE---KKRPHTESPGRRSHRHSSGSSHSPSLSS 267
Query: 62 QGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQR 121
+ R + D+ R + + + S G +R Q +G G R
Sbjct: 268 HYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGR 327
Query: 122 RGSRSSP--SADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQR----RPAGGTGQRR 175
GS SP + R++ AAAAP P +RG + + + R AGG G+RR
Sbjct: 328 PGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRR 387
Query: 176 GSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPS 235
+ + R ++A AP RG +R+P RPA G SS S
Sbjct: 388 ----------RRRRRRRRSRSSASAPRRRG----RRRP-----RPAPPRG------SSRS 422
Query: 236 ADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQ 295
+ R+ AP P P+ R GG G+R
Sbjct: 423 LSRARSSSDSGSGRGAPGP----------GPEPGSERGHGGHGKRA-------------- 458
Query: 296 DREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAA 355
+E A PA TS G G+R G SS+ G R ++
Sbjct: 459 -KERPPRARPASTSPS---------------PGAHGRRGGPEGKSSSRSPGPHPRSWSSS 502
Query: 356 AAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRR-----GSGSSPSADQQRAQDREEEVRKW 410
+ P+ S R+ +++P P R P+ R G A+ RA+ R
Sbjct: 503 RS--PSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPI 560
Query: 411 KKR 413
+KR
Sbjct: 561 RKR 563
Score = 74.3 bits (181), Expect = 2e-13
Identities = 98/402 (24%), Positives = 146/402 (36%), Gaps = 54/402 (13%)
Query: 48 GQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSS----GHR-T 102
G G +P D G D + A+ R + +A+ P GHR +
Sbjct: 122 GAEPGLEYAPFDDDDGPVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRS 181
Query: 103 EKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRK-RQ 161
K++RL+ +C + R+ +S + R+ +S+ R EK K ++
Sbjct: 182 RKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKK 241
Query: 162 QPQRRPAGGTGQRRGSGS--SPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCR 219
+P G R SGS SPS + R +P+ S HR E RK +
Sbjct: 242 RPHTESPGRRSHRHSSGSSHSPSLSSHYSDSR------SPSRLSPKHRDEGRKTGSQRSS 295
Query: 220 PA-----------------GGTGQRRGSR-----------SSPSADQQRAQDREEEAAAA 251
+ GG+GQR G+ PS+ R +D+ AAAA
Sbjct: 296 GSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDK--AAAAA 353
Query: 252 PAPTSRGHR--TEKRKPQQPQR--RPAGGTG--QRRGSGYSPSADQQGAQDREEEAAAAP 305
P P +RG + + P R R AGG G +RR S A R P
Sbjct: 354 PTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRP 413
Query: 306 APTSSGHRTEKRKRLQLQC---QPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTS 362
AP R+ R R + A G G GS + + A++R A A S
Sbjct: 414 APPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPS 473
Query: 363 SGHRTEKRKPQQPQRRPAAGTGQRRGSGS-SPSADQQRAQDR 403
G + P+ + G R S S SPS + R+ ++
Sbjct: 474 PGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEK 515
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 71.2 bits (173), Expect = 2e-12
Identities = 87/416 (20%), Positives = 155/416 (37%), Gaps = 50/416 (12%)
Query: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG 63
RQ+E++ + RE + E E+ ++Q + + +R D+
Sbjct: 413 RQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDR 472
Query: 64 AQDREEEAAA----APAADQQRAQDREEEAAAAPVPTSSGHRTEK--------RKRLQLQ 111
++RE+E +P ++A+ ++EAA + +K+L +
Sbjct: 473 EKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVS 532
Query: 112 CQPAGGTGQRRGSRSSPSA-DQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGG 170
P+ +R+ S SS SA + R+ R + + SR + R +
Sbjct: 533 VSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSF 592
Query: 171 TGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGS 230
+G R ++ R ++ +P+PT HR R +P P G G++
Sbjct: 593 SGSR-------------SRSRSFSSSPSPSPTPSPHRPSIRTKGEP-APPPGKAGEKSVK 638
Query: 231 RSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPA-----GGTGQRRGSGY 285
+ +P +A + A P PT G E R+ ++P R P G+G GS Y
Sbjct: 639 KPAPPPAPPQAT---KTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSY 695
Query: 286 SPSADQQG--AQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSAN 343
S S+ + + ++A + +SS H + P +SS +
Sbjct: 696 SGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSS---------ASSRS 746
Query: 344 QQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRG-SGSSPSADQQ 398
AQ R+E+ + G + EKRK + P + G S PS QQ
Sbjct: 747 PAPAQTRKEKGKS---KKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQ 799
Score = 59.3 bits (142), Expect = 6e-09
Identities = 64/307 (20%), Positives = 111/307 (36%), Gaps = 33/307 (10%)
Query: 120 QRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGS 179
+R R + +++R ++R+ E R E+ K +Q ++ +R
Sbjct: 405 ERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKD 464
Query: 180 SPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSP----- 234
D+ ++RE+E P P S + + +P + + G +R P
Sbjct: 465 RQHRDRDREKEREKEKGK-PKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSK 523
Query: 235 --------SADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYS 286
S RA+ R + +A+ A S R+ R + R S YS
Sbjct: 524 SPKKKLGVSVSPSRAR-RRRKTSASSASASNSSRSSSRSSSYSGS--GSSRSRSRSSSYS 580
Query: 287 PSADQQG---------AQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSG 337
+ + ++ R ++ +P+PT S HR R + +PA G+
Sbjct: 581 SYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTK----GEPAPPPGKAGEKS 636
Query: 338 CSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAG---TGQRRGSGSSPS 394
A + A P PT G E R+ ++P R P +G GSGSS S
Sbjct: 637 VKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYS 696
Query: 395 ADQQRAQ 401
R++
Sbjct: 697 GSSSRSR 703
Score = 32.7 bits (73), Expect = 0.63
Identities = 34/185 (18%), Positives = 64/185 (34%), Gaps = 15/185 (8%)
Query: 127 SPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQ 186
SP D +D E+ + R +++ R A + PS +++
Sbjct: 6 SPERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVR--ASDLEDEESAARGPSQEEE 63
Query: 187 GAQDREEEAAAAPAPTSRGHRTEK--RKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDR 244
EE+ A+ P + + R P C G G+ R+S D+ + R
Sbjct: 64 DNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEE--DRTSDLRDEASSVTR 121
Query: 245 E---------EEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQ 295
E EE PAP + EK + + + G + +G +++ +
Sbjct: 122 ELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLE 181
Query: 296 DREEE 300
+E+
Sbjct: 182 AAKEK 186
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 70.9 bits (172), Expect = 2e-12
Identities = 99/431 (22%), Positives = 167/431 (38%), Gaps = 64/431 (14%)
Query: 1 MKPRQKEQDTRLRKLRES-SEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSA 59
+KP+ K +K + S S+ D E+E K Q+P+ P Q + A
Sbjct: 150 VKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPK----NQKPKITPVTVKAQTKAPPKPARA 205
Query: 60 DQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTG 119
+ A + ++++ ++ EE+AAA P +T +K++ + T
Sbjct: 206 APKIANGKAASSSSSSSSSSSSDDSEEEKAAATP------KKTVPKKQVVAKAPVKAATT 259
Query: 120 QRRGSRSSP--SADQQRAQDREEEAAAAP---VPTSRGHRTEKRKRQQPQRRPAGGTGQR 174
R S SS S+D++ Q + + P VP +K QP ++ Q+
Sbjct: 260 PTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAV--EKQQ 317
Query: 175 RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSP 234
S S+D+ + EE+ A S+ T K P ++ SS
Sbjct: 318 PVESSEDSSDESDSSSEEEKKPPTKAVVSKA--TTKPPP-----------AKKAAESSSD 364
Query: 235 SADQQRAQDREEEAAAAPAPTSRGHRTEKR--------KPQQPQRRPAGGTGQRRGSGYS 286
S+D ++D +EA + PA T++ + KP ++P GG +
Sbjct: 365 SSDSDSSED--DEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKAD 422
Query: 287 PSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQG 346
S+ ++ + EEE T+ T K L L + A +GS SSS +
Sbjct: 423 SSSSEEESSSSEEEKTKKMVATTKPKATAK-AALSLPAKQA-----PQGSRDSSSDSDSS 476
Query: 347 AQDREEEAAAAPVPTSSGHRTEKRKPQQ------PQRRPAAGTGQRRGSGSSPSADQQRA 400
+ + EEE + K+KPQ+ P + +A G+ S SS S D +
Sbjct: 477 SSEEEEE--------KTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDD---S 525
Query: 401 QDREEEVRKWK 411
+ EEE K K
Sbjct: 526 SEEEEEKLKGK 536
Score = 64.7 bits (156), Expect = 1e-10
Identities = 88/417 (21%), Positives = 151/417 (36%), Gaps = 68/417 (16%)
Query: 17 ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPS-ADQQGAQDREEEAAAAP 75
E S D E++K +P++ +PQ + A ++ S S S + + + ++ P
Sbjct: 130 EESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITP 189
Query: 76 AADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRA 135
+ + + + A AAP + G+ S SS S+
Sbjct: 190 VTVKAQTKAPPKPARAAPKIAN---------------------GKAASSSSSSSSSSSSD 228
Query: 136 QDREEEAAAAPVPTSRGHRTEKRKRQQPQRRP--AGGTGQRRGSGSSPSADQQGAQDREE 193
EE+AAA P T K+Q + P A T R+ S S S+ EE
Sbjct: 229 DSEEEKAAATPKKTVP-------KKQVVAKAPVKAATTPTRKSSSSEDSSSD------EE 275
Query: 194 EAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTG--------QRRGSRSSPSADQQRAQDRE 245
E P G + P P + + GT Q+ S S+D+ + E
Sbjct: 276 EEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEE 335
Query: 246 EEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAP 305
E+ A S+ T K P ++ S S+D ++D +EA + P
Sbjct: 336 EKKPPTKAVVSKA--TTKPPP-----------AKKAAESSSDSSDSDSSED--DEAPSKP 380
Query: 306 APTSSGHRTEKR--------KRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAA 357
A T+ + K QP GG + SS++++ + EEE
Sbjct: 381 AGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKK 440
Query: 358 PVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEEVRKWKKRV 414
V T+ T K P ++ G+ S S++++ + + V+K ++V
Sbjct: 441 MVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKV 497
Score = 60.5 bits (145), Expect = 3e-09
Identities = 84/412 (20%), Positives = 157/412 (38%), Gaps = 54/412 (13%)
Query: 24 WLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAP----AADQ 79
WL++ K P+++ Q A G ++ + S+D + + + EEE P A
Sbjct: 57 WLKSAKV----PERKLQ---ANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPA 109
Query: 80 QRAQDREEEAAAAPVPTSSGHRT--------EKRKRLQLQCQPAGGTGQRRGSRS-SPSA 130
+R +AAA +SS + +K++ +Q +P + ++ S +
Sbjct: 110 KRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDS 169
Query: 131 DQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQR-RPAGGTGQRRGSGSSPSADQQGAQ 189
D + + E P T + + + +P R P G+ S SS S+
Sbjct: 170 DSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDD 229
Query: 190 DREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAA 249
EE+AAA P T + + P + A T R+ S S S+ EEE
Sbjct: 230 SEEEKAAATPKKTVPKKQVVAKAPVK-----AATTPTRKSSSSEDSSSD------EEEEQ 278
Query: 250 AAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTS 309
P G + P P + + GT + + ++Q + E+++ +S
Sbjct: 279 KKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPK-----KAVEKQQPVESSEDSSDESDSSS 333
Query: 310 SGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEK 369
+ K + + ++ S S++ ++D +EA + P T+ +
Sbjct: 334 EEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSED--DEAPSKPAGTT---KNSS 388
Query: 370 RKP----QQPQRRPAAGTGQRRGSG--------SSPSADQQRAQDREEEVRK 409
KP + P +PAA Q G G S S++++ + EE+ +K
Sbjct: 389 NKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKK 440
Score = 54.7 bits (130), Expect = 2e-07
Identities = 64/311 (20%), Positives = 116/311 (37%), Gaps = 57/311 (18%)
Query: 18 SSEGDQWLENEK---TKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAA 74
S E D E EK TK + + + PA ++ SS S+D ++D +EA +
Sbjct: 326 SDESDSSSEEEKKPPTKAVVSKATTKPPPA----KKAAESSSDSSDSDSSED--DEAPSK 379
Query: 75 PAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQR 134
PA + + ++ +P K QP GG + ++ S+ ++
Sbjct: 380 PAGTTKNSSNKPAVTTKSPAV----------KPAAAPKQPVGGGQKLLTRKADSSSSEEE 429
Query: 135 AQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEE 194
+ EEE V T++ T K P ++ G+ SS +D +++ EE+
Sbjct: 430 SSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGS-----RDSSSDSDSSSSEEEEEK 484
Query: 195 AAAAPAPTSRGHRTEKRKPQQ------PQCRPAGGTGQRRGSRSSPSADQQRAQDREEEA 248
+ + K+KPQ+ P + G+ S SS S D ++ + +
Sbjct: 485 TSKSAV---------KKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKG 535
Query: 249 AAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPT 308
+P +PQ P+ + G + +++ EEE A
Sbjct: 536 KGSP------------RPQAPKANGTSALTAQNGKA------AKNSEEEEEEKKKAAVVV 577
Query: 309 SSGHRTEKRKR 319
S +KRK+
Sbjct: 578 SKSGSLKKRKQ 588
Score = 35.4 bits (80), Expect = 0.097
Identities = 37/173 (21%), Positives = 70/173 (40%), Gaps = 20/173 (11%)
Query: 10 TRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQ------------PAGGTGQRRGSGSSP 57
TR S E E EKTK + +P+ P G S SS
Sbjct: 418 TRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSS 477
Query: 58 SADQQ-----GAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQC 112
S +++ A ++ + A AA + A ++ +A ++ +S E+ ++L+ +
Sbjct: 478 SEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKG 537
Query: 113 QPAGGTGQRRGSRSSPSADQQRA---QDREEEAAAAPVPTSRGHRTEKRKRQQ 162
P + G+ + + + + A ++ EEE A V S+ +KRK+ +
Sbjct: 538 SPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNE 590
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 70.9 bits (172), Expect = 2e-12
Identities = 91/406 (22%), Positives = 155/406 (38%), Gaps = 69/406 (16%)
Query: 46 GTGQRRGSGSSPSADQQGAQDREEEA----AAAPAADQQRAQDREEEAAAAPVPTSSGHR 101
GT +R +P + + EE+ AAA + Q+R R+ + +++ +SS
Sbjct: 444 GTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSE 503
Query: 102 TEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQD-----------------REEEAAA 144
E+ KR ++ G + SRS+ + ++R ++ R +
Sbjct: 504 DERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSP 563
Query: 145 APVPTSRGHRTEKRKRQQPQRRPAGGTG---------QRRGSGSSPSADQQGAQDREEEA 195
AP P R T +R+ P P + QRR S S P + + +
Sbjct: 564 APPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKR 623
Query: 196 AAAPAPTSRGHRTEKRKPQQ------PQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAA 249
A+P+P + + P+Q + P+ + R+G SSPS + A+ +
Sbjct: 624 RASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKG--SSPSRSTREARSPQPNKR 681
Query: 250 AAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTS 309
+P+P R +T P P RR A + QRR S SPS P
Sbjct: 682 HSPSPRPRAPQTSSSPP--PVRRGASSSPQRRQSP-SPST----------------RPIR 722
Query: 310 SGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEK 369
RT + K+++ P+ + +R S S S + + A ++ A P P S
Sbjct: 723 RVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPA---AKKPPAPPSPVQS------ 773
Query: 370 RKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEEVRKWKKRVD 415
Q P + ++ +PS R D+E +K KK+ D
Sbjct: 774 ---QSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKD 816
Score = 63.2 bits (152), Expect = 4e-10
Identities = 91/440 (20%), Positives = 169/440 (38%), Gaps = 58/440 (13%)
Query: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPLR---PQQQPQCQPAGGTGQRRGSGSSPSAD 60
R KE+ R+ RE S + ++ P R P ++ + + + + R SPS
Sbjct: 154 RDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSP- 212
Query: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAA----------PVPTS---SGHRTEKRKR 107
A +++E+ P + + +EA + P+P S + K+++
Sbjct: 213 ---APEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEK 269
Query: 108 LQLQCQPAGGTGQRRGSRS---SPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQ 164
+ + +P + + SR+ SPS + R + R + +P R +R+ P
Sbjct: 270 EKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPP 329
Query: 165 RRPAGGTGQRR----------------GSGSSPSADQQGAQDREEEAAAAPAPTSRGHRT 208
RR RR GS SS S+ + + ++ + P +
Sbjct: 330 RRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLS 389
Query: 209 EKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTS----RGHRTEKR 264
P + + RP+ +R SP+ QQ + R+ + +P TS + TEKR
Sbjct: 390 PSASPPRRRHRPSPPATPPPKTRHSPT-PQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKR 448
Query: 265 KPQQPQRRPAG---GTGQRRGSGYSPSAD---QQGAQDREEEAAAAPAPTSSGHRTEKRK 318
+ P +P + G +AD Q+ R+ + +++ + +SS E+ K
Sbjct: 449 ESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPK 508
Query: 319 RLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEA-----AAAPVPTSSGHRTEKRKPQ 373
R ++ G G+RR S SA+ + ++E + +P P + R
Sbjct: 509 RSHVK---NGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAP 565
Query: 374 QPQRRPAAGTGQRRGSGSSP 393
P+RR RR + S P
Sbjct: 566 PPRRRRTPTPPPRRRTPSPP 585
Score = 49.7 bits (117), Expect = 5e-06
Identities = 51/274 (18%), Positives = 101/274 (36%), Gaps = 21/274 (7%)
Query: 49 QRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRL 108
QRR S S P + + + A+P+ +R + +P P KR+
Sbjct: 601 QRRYSPSPPPKRRTASPPPPPKRRASPSPPPKR------RVSHSPPPKQRSSPVTKRRSP 654
Query: 109 QLQCQPAGGTGQRRGSRS--SPSADQQRA---QDREEEAAAAPVPTSRGHRTEKRKRQQP 163
L + G+ R +R SP +++ + + R + +++P P RG + ++RQ P
Sbjct: 655 SLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSP 714
Query: 164 Q--RRPAGGTGQ-------RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQ 214
RP + ++ + SP + ++ + R + PA + Q
Sbjct: 715 SPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQ 774
Query: 215 QPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPA 274
P + ++ +PS R D+E + H+ +K+ + + +
Sbjct: 775 SPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKE 834
Query: 275 GGTGQRRGSGYSPSADQQGAQD-REEEAAAAPAP 307
+ +P+A +EE AAP P
Sbjct: 835 KAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEP 868
Score = 49.3 bits (116), Expect = 6e-06
Identities = 84/400 (21%), Positives = 141/400 (35%), Gaps = 55/400 (13%)
Query: 5 QKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGA 64
Q+ + R + + SS+ +E +P R + G G+RR S SA
Sbjct: 480 QQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKN-----GEVGRRRRHSPSRSASPS-- 532
Query: 65 QDREEEAAAAPAADQQRAQD-----REEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTG 119
R+ + +P ++R+ R + AP P T +R P +
Sbjct: 533 -PRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSP 591
Query: 120 ---------QRRGSRSSPSADQQRAQDREEEAAAAPVPTSR---GHRTEKRKRQQP-QRR 166
QRR S S P + + + A+P P + H ++R P +R
Sbjct: 592 SPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKR 651
Query: 167 PAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQ 226
+ + GSSPS + A+ + +P+P R +T P P R A + Q
Sbjct: 652 RSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPP--PVRRGASSSPQ 709
Query: 227 RRGSRSSPSADQQRAQDREEEA-----AAAPAPTSRGHRTEKRK--------PQQPQRRP 273
RR S SPS R R E AA+P+P S + R ++P P
Sbjct: 710 RRQS-PSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPP 768
Query: 274 AGGTGQRRGSGYSPSADQQGAQ------------DREEEAAAAPAPTSSGHRTEKRKRLQ 321
+ Q + +SP+ + A+ D+E H+ +K+ +
Sbjct: 769 SPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKH 828
Query: 322 LQCQPAGGTGQRRGSGCSSSANQQGAQD-REEEAAAAPVP 360
+ + + + +A +EE AAP P
Sbjct: 829 KKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEP 868
Score = 48.9 bits (115), Expect = 8e-06
Identities = 67/356 (18%), Positives = 126/356 (35%), Gaps = 57/356 (16%)
Query: 103 EKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQ 162
E+ K ++ Q + + + S ++R++ + +P P R + +++
Sbjct: 137 EQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRS 196
Query: 163 PQRRPAGGTGQRRGSGS------SPSADQQGAQDREEEAAAA------------------ 198
R P T R S + +P + + +E A
Sbjct: 197 HSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEP 256
Query: 199 --PAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAP---- 252
P+P + ++++ +P+ R + R SR SPS + R + R + +P
Sbjct: 257 KEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSR-SPSHTRPRRRHRSRSRSYSPRRRP 315
Query: 253 ----APTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPT 308
P+ R +R P P+ R + +RR SA G+ + + P
Sbjct: 316 SPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRS---SASLSGSSSSSSSSRSRSPPK 372
Query: 309 SSGHRTEKRKRLQLQCQPAGGTGQRRGSGC----------SSSANQQGAQDREEEAAAAP 358
RT R + P+ +RR S QQ + R+ + +P
Sbjct: 373 KPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSP 432
Query: 359 VPTS---SGHR-TEKRKPQQPQRRP-----AAGTGQRRGSGSSPSADQQRAQDREE 405
TS + H+ TEKR+ P +P + + G ++ + QQR Q R +
Sbjct: 433 GRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQ 488
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 66.2 bits (160), Expect = 5e-11
Identities = 84/396 (21%), Positives = 140/396 (35%), Gaps = 34/396 (8%)
Query: 17 ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA 76
E+ E + ++ E P+ + + QP + + + + +GA+ +E E AA A
Sbjct: 1891 ETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEA 1950
Query: 77 ADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQ 136
Q + + E+ A + ++++ Q A G Q + Q
Sbjct: 1951 EGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQ 2010
Query: 137 DREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAA 196
+ EEEA P S G + + + + G T + G + P +D A + EEEA
Sbjct: 2011 EAEEEAQ----PESDGVEAQPKSEGEEAQEVEGETQKTEGD-AQPESDGVEAPEAEEEAQ 2065
Query: 197 AAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTS 256
A + + + A G Q S + A+ ++A AP +
Sbjct: 2066 EAEGEVQEAEGEAHPESEDVDAQEAEGEAQ----PESEGVEAPEAEGEAQKAEGIEAPET 2121
Query: 257 RGH-RTEKRKPQQPQRRPAGGTGQRRGSGY---------SPSADQQGAQDREEEA----A 302
G + E + P+ A G Q G P ++ AQ+ EEEA
Sbjct: 2122 EGEAQPESEGIEAPE---AEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELE 2178
Query: 303 AAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREE-----EAAAA 357
AP + G + + ++ A G Q G + ++ AQ E EA
Sbjct: 2179 GVEAPEAEGEAQPESE--GIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGE 2236
Query: 358 PVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSP 393
P S G T+ K PQ G + SSP
Sbjct: 2237 AQPESEG-ETQGEKKGSPQVSLGDGQSEEASESSSP 2271
Score = 64.3 bits (155), Expect = 2e-10
Identities = 80/372 (21%), Positives = 140/372 (37%), Gaps = 42/372 (11%)
Query: 17 ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAA-AP 75
+ +EGD E++ + P+ + + Q A G Q + P ++ AQ+ E EA +
Sbjct: 2042 QKTEGDAQPESDGVEA--PEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESE 2099
Query: 76 AADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRA 135
+ A+ ++A P + G + Q + G + P ++ A
Sbjct: 2100 GVEAPEAEGEAQKAEGIEAPETEG---------EAQPESEGIEAPEAEGEAQPESEGVEA 2150
Query: 136 QDREEEAAAAPVPTSRGHRTEKRKRQ-QPQRR-----PAGGTGQRRGSG-SSPSADQQ-- 186
QD E EA P S G ++ + + QP+ A G Q G +P A+ +
Sbjct: 2151 QDAEGEAQ----PESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQ 2206
Query: 187 ----GAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQ 242
G + E E A P P G T + + + G+++GS P Q
Sbjct: 2207 PELEGVEAPEAEEEAQPEP--EGVETPEAEGEAQPESEGETQGEKKGS---PQVSLGDGQ 2261
Query: 243 DREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTG--QRRGSGYSPSADQQGAQDREEE 300
E +++P P R P +RP TG R S + + D
Sbjct: 2262 SEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLG 2321
Query: 301 AAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQD----REEEAAA 356
+P S+G +RK ++ P T ++ + S +QGA + +E++A
Sbjct: 2322 DTRSPDAKSTGTPHAERKATRM--YPESSTSEQEEAPLGSRTPEQGASEGYDLQEDQALG 2379
Query: 357 APVPTSSGHRTE 368
+ PT + R +
Sbjct: 2380 SLAPTEAVGRAD 2391
Score = 38.1 bits (87), Expect = 0.015
Identities = 56/295 (18%), Positives = 94/295 (31%), Gaps = 22/295 (7%)
Query: 133 QRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQ--- 189
QR + + AA V + H R G G +G G D +G+Q
Sbjct: 1694 QRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGVDEGEDGEGSQRLN 1753
Query: 190 -DREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRG----SRSSPSADQQRAQDR 244
D++ + A R K + G ++ G R +D
Sbjct: 1754 RDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDN 1813
Query: 245 EEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAA- 303
+ AAA G + P+ A G Q G + AQ+ E EA
Sbjct: 1814 LQGEAAAGGDQDPGQSDGAEGIEAPE---AEGEAQPESEGVEAPEAEGDAQEAEGEAQPE 1870
Query: 304 ---APAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVP 360
AP + G + + ++ A Q G + ++ AQ E A
Sbjct: 1871 SEDVEAPEAEGEAQPESE--DVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETE 1928
Query: 361 TSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEEVRKWKKRVD 415
+E + Q+ + GQ + P ++ +Q+ EEE + + V+
Sbjct: 1929 GEDEPESEGAEAQEAEEAAQEAEGQ-----TQPESEVIESQEAEEEAQPESEDVE 1978
Score = 37.0 bits (84), Expect = 0.033
Identities = 96/424 (22%), Positives = 137/424 (32%), Gaps = 94/424 (22%)
Query: 38 QPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTS 97
Q PA TG GS S + +D + A+ + AQ E A +
Sbjct: 450 QDSASPASSTGLPEGSEPESSCCPRTPEDGVDSASPS-------AQIGAERKAGGSLGED 502
Query: 98 SGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEK 157
G L AG G +G R +P A R EE A++ S G
Sbjct: 503 PG----------LCIDGAGLGGPEQGGRLTPRA-------RSEEGASSDSSASTGSHEGS 545
Query: 158 RKRQQPQRRPAGGTGQRRGSGSSPSADQQG---------AQDREEEAAAAPAPTSRGHRT 208
+ RP G G+ R S A + G + R ++ A T
Sbjct: 546 ---SEWGGRPQGCPGKARAETSQQEASEGGDPASPALSLSSLRSDDLQAETQGQGTEQAT 602
Query: 209 EKRKPQQPQCRPAGGTGQRRGSRSSPS---ADQQRAQDREEEAAAAPAPTS--------R 257
++P + G+ S+PS + QQ + A+A +P+S R
Sbjct: 603 GAAVTREPLVLGLSCSWDSEGASSTPSTCTSSQQGQRRHRSRASAMSSPSSPGLGRVAPR 662
Query: 258 GH----------------RTEKRKPQQPQRRPAGGTGQ-RRGSGYSPSADQQGAQD-REE 299
GH K+ P+ P+RR A G R SG S S Q + + R
Sbjct: 663 GHPRHSHYRKDTHSPLDSSVTKQVPRPPERRRACQDGSVPRYSGSSSSTRTQASGNLRPP 722
Query: 300 EAAAAPAP----------TSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCS---------S 340
+ + P+ T + H AG G CS
Sbjct: 723 SSGSLPSQDLLGTSSATVTPAVHSDFVSGVSPHNAPSAGWAGDAGSRTCSPAPIPPHTSD 782
Query: 341 SANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQ----PQR-----RPAAGTGQRRGSGS 391
S ++ GA EEA P P SS + +P+Q P R +P Q G
Sbjct: 783 SCSKSGAASLGEEARDTPQP-SSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQEAQRGP 841
Query: 392 SPSA 395
SP A
Sbjct: 842 SPEA 845
Score = 34.7 bits (78), Expect = 0.16
Identities = 64/280 (22%), Positives = 90/280 (32%), Gaps = 35/280 (12%)
Query: 29 KTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEE 88
K P P+++ CQ G+ R SS + Q R + + P+ QD
Sbjct: 684 KQVPRPPERRRACQD--GSVPRYSGSSSSTRTQASGNLRPPSSGSLPS------QDLLGT 735
Query: 89 AAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRS----------SPSADQQRAQDR 138
++A P ++ + P+ G GSR+ S S + A
Sbjct: 736 SSATVTPAV---HSDFVSGVSPHNAPSAGWAGDAGSRTCSPAPIPPHTSDSCSKSGAASL 792
Query: 139 EEEAAAAPVPTSRGHRTEKRKRQQ---PQR-----RPAGGTGQRRGSGSSPSADQQGAQD 190
EEA P P+S R Q P R +P Q G SP A +
Sbjct: 793 GEEARDTPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQEAQRGPSPEASWLCGRY 852
Query: 191 REEEAAAAPAPTSRGHRTEKR-KPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAA 249
P P R Q R GG+ Q + P+ ++
Sbjct: 853 CPTPPRGRPCPQRRSSSCGSTGSSHQSTARGPGGSPQEGTRQPGPTPSPGPNSGASRRSS 912
Query: 250 AAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSA 289
A+ SRG EK R G GQ SG SPS+
Sbjct: 913 ASQGAGSRGLSEEKTL-----RSGGGPQGQEEASGVSPSS 947
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 64.7 bits (156), Expect = 1e-10
Identities = 87/425 (20%), Positives = 157/425 (36%), Gaps = 61/425 (14%)
Query: 8 QDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG-AQD 66
++ ++ + SS+G + +++ Q P + T +RRGS S D +G ++D
Sbjct: 252 EENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESR--TRKRRGSRVSQDRDSEGHSED 309
Query: 67 REEEAAAAPAADQQRAQDREEEAAAAPVP-----TSSGHRTEKRKRLQLQCQPAGGTGQR 121
E + +A A ++ + + P S GH + + ++
Sbjct: 310 SERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSAD--------------SSRQ 355
Query: 122 RGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQ-------- 173
G+R + ++ + + E+A ++P H + ++ R A G GQ
Sbjct: 356 SGTRHAETSSRGQTASSHEQARSSP---GERHGSGHQQSADSSRHSATGRGQASSAVSDR 412
Query: 174 -RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRS 232
RGS S ++D +G + + + + GH + Q Q G +G+R G RS
Sbjct: 413 GHRGSSGSQASDSEGHSENSDTQSVS------GHGKAGLRQQSHQESTRGRSGERSG-RS 465
Query: 233 SPSADQQRAQDREEEAAAAPAPTSRGHR-TEKRKPQQPQRRPAGGTGQRRGSGYSPSADQ 291
S Q ++ + A ++ G + + + + R A GQ G+ P + +
Sbjct: 466 GSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGH-PGSSR 524
Query: 292 QGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDRE 351
G Q E + + S H + + G + G S SA++Q R
Sbjct: 525 GGRQGSHHEQSVNRSGHSGSHHSHTTSQ--------GRSDASHGQSGSRSASRQ---TRN 573
Query: 352 EEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRG------SGSSPSADQQRAQDREE 405
EE + S E R G GQ G GSS S D +Q E
Sbjct: 574 EEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSD-SQGHSE 632
Query: 406 EVRKW 410
+ +W
Sbjct: 633 DSERW 637
Score = 62.4 bits (150), Expect = 7e-10
Identities = 92/450 (20%), Positives = 148/450 (32%), Gaps = 70/450 (15%)
Query: 15 LRESSEGDQWLENEKTKPLRPQQQP-QCQPAGGTGQRRGSGSSPSADQQG---------- 63
+R+ S +Q +N + + Q + P R+GS S D+ G
Sbjct: 816 VRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTT 875
Query: 64 AQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRG 123
+Q R + + + R EE + S E + G GQ G
Sbjct: 876 SQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEG 935
Query: 124 SRSSPSADQQRAQDREEEAAAAPV-----PTSRGHR-TEKRKRQQPQRRPAGGTGQRRGS 177
SR+S +QD + E + SR HR + + + + R P R G
Sbjct: 936 SRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGH 995
Query: 178 GSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSAD 237
G S + +Q E ++ A +S H + P G+R GSR SAD
Sbjct: 996 GHSADSSRQSGTPHAETSSGGQAASS--HEQARSSP-----------GERHGSRHQQSAD 1042
Query: 238 QQRAQ--DREEEAAA-----------APAPTSRGHRTE---------------KRKPQQP 269
R R + ++A + A S GH E ++ Q+
Sbjct: 1043 SSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQES 1102
Query: 270 QRRPAGGTGQRRGSG-YSPSADQQG---------AQDREEEAAAAPAPTSSGHRTEKRKR 319
R +GG R GS Y S +Q + R + + A SS H + +
Sbjct: 1103 ARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQ 1162
Query: 320 LQLQCQPAGGTGQRRGSGCSSSANQQG--AQDREEEAAAAPVPTSSGHRTEKRKPQQPQR 377
++ P G R+GS S ++ G + S G + +Q ++
Sbjct: 1163 DTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRK 1222
Query: 378 RPAAGTGQRRGSGSSPSADQQRAQDREEEV 407
+G G R A R +V
Sbjct: 1223 DKQSGDGSRHSGSRHHEAASWADSSRHSQV 1252
Score = 62.0 bits (149), Expect = 1e-09
Identities = 83/378 (21%), Positives = 130/378 (34%), Gaps = 37/378 (9%)
Query: 51 RGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQL 110
RGS S ++D +G + + + + Q +E+ SG ++
Sbjct: 415 RGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVST 474
Query: 111 QCQPAGG-------TGQRRGSRSSPSADQQR--AQDREEEAAAAPVPTSRGHRTEKRKRQ 161
QP TG R+GS + D R A ++ +SRG R Q
Sbjct: 475 HEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQ 534
Query: 162 QPQRRPAGG------TGQRRGSGSSPSADQQGA--QDREEEAAAAPAPTSRGHRTEKRKP 213
R G T Q R S + + A Q R EE + S E
Sbjct: 535 SVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQ 594
Query: 214 QQPQCRPAGGTGQRRGSRSSPSADQQRAQDRE-----EEAAAAPAPTSRGHR-TEKRKPQ 267
G GQ G R+S + +QD + E++ SR H + + + +
Sbjct: 595 ADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSR 654
Query: 268 QPQRRPAGGTGQRRGSGYSPSADQ-------QGAQDREEEAAAAPAPTSSGHRTEKRKRL 320
R P R G G+S + + Q + + ++ A +S+G R R +L
Sbjct: 655 DGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQL 714
Query: 321 Q-LQCQPAGGTGQRRGSGCSSSANQQG-----AQDREEEAAAAPVPTSSGHRTEKRKPQQ 374
Q GTG + S + +G A D E + + + SGH Q
Sbjct: 715 QSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQS 774
Query: 375 PQRRPAAGTGQR-RGSGS 391
Q +G+R R SGS
Sbjct: 775 HQESARDRSGERSRRSGS 792
Score = 58.9 bits (141), Expect = 8e-09
Identities = 78/378 (20%), Positives = 130/378 (34%), Gaps = 40/378 (10%)
Query: 51 RGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHR-------TE 103
RG S ++D +G + + + + Q +E+A SSG +
Sbjct: 2037 RGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVST 2096
Query: 104 KRKRLQLQCQPAGGTGQRRGSRSSPSADQQR---AQDREEEAAAAPVPTSRGHRTEKRKR 160
+ Q A TG R+GS + D R +Q+ ++ P P SRG R +
Sbjct: 2097 HEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGP-SRGGRQGSHQE 2155
Query: 161 QQPQRRPAGG------TGQRRGSGSSPSADQQGAQDR--EEEAAAAPAPTSRGHRTEKRK 212
Q R G T Q R S + + A + ++E + + S H E
Sbjct: 2156 QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASS 2215
Query: 213 PQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRG------HRTEKRKP 266
G GQ G R+S +QD + E + + G H + + +
Sbjct: 2216 WADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQS 2275
Query: 267 QQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAP-------TSSGHRTEKRKR 319
+ R P R G G+S + +Q E ++ A +S+G R +
Sbjct: 2276 RDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQ 2335
Query: 320 LQLQCQPAGGTGQRRGSGCSSSANQQG-----AQDREEEAAAAPVPTSSGH---RTEKRK 371
G G + S + +G A D E + + + S H ++
Sbjct: 2336 QSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQS 2395
Query: 372 PQQPQRRPAAGTGQRRGS 389
Q+ R +AG R GS
Sbjct: 2396 HQESTRGRSAGRSGRSGS 2413
Score = 58.2 bits (139), Expect = 1e-08
Identities = 77/381 (20%), Positives = 132/381 (34%), Gaps = 46/381 (12%)
Query: 51 RGSGSSPSADQQGAQDREEEAAAAPAADQQ------RAQDREEEAAAAPVPTSSGHRTEK 104
R SGS+ AQ++ + + P + Q+ + D ++ TSSG +
Sbjct: 2582 RWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAAS 2641
Query: 105 RKRLQLQCQPAGGTGQRRGSRSSPSADQQR-------------------------AQDRE 139
Q G+R GS SAD R A D E
Sbjct: 2642 SHE-----QARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNE 2696
Query: 140 EEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAP 199
+ + + H +Q Q G +G+ G S Q ++ E +
Sbjct: 2697 GHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGS-FLYQVSTHEQSESSHGWT 2755
Query: 200 APTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGH 259
P++RG + + + Q R + + R P + + Q E + + S H
Sbjct: 2756 GPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSH 2815
Query: 260 RTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKR 319
+ Q G +G R S + + +Q G R + A T H R
Sbjct: 2816 HSHTTS-QGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEAST---HADISRHS 2871
Query: 320 LQLQCQPAGGTGQRR-GSGCSSSANQQG-AQDREEEAAAAPVPTSSGHRTEKRKPQQPQR 377
+Q Q G RR GS S ++ +G ++D E + +A + + H + + + + R
Sbjct: 2872 QAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSA---SRNHHGSAQEQLRDGSR 2928
Query: 378 RPAAGTGQRRGSGSSPSADQQ 398
P + R G G S + +Q
Sbjct: 2929 HPRSHQEDRAGHGHSADSSRQ 2949
Score = 57.0 bits (136), Expect = 3e-08
Identities = 86/421 (20%), Positives = 142/421 (33%), Gaps = 67/421 (15%)
Query: 42 QPAGGTGQRRGSGSSP---SADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSS 98
Q A TG R+GS S+ +QD ++ P + + Q E + S
Sbjct: 1457 QTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSV----DRS 1512
Query: 99 GHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKR 158
GH Q + GQ S P + ++ ++ E+ + SR H E
Sbjct: 1513 GHSGYHHSHTTPQGRSDASHGQ-----SGPRSASRQTRNEEQSGDGSRHSGSRHH--EPS 1565
Query: 159 KRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQC 218
R R G G+ GS +S +QDR+ E GH + + +
Sbjct: 1566 TRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSE----------GHSEDSERRSESAS 1615
Query: 219 RPAGGTGQ---RRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAG 275
R G+ + R GSR+ S + RA ++ + T + + Q +
Sbjct: 1616 RNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARS 1675
Query: 276 GTGQRRGSGYSPSAD---QQGAQDREEE----------AAAAPAPTSSGHRTEK------ 316
G+R GS + SAD G R++ ++ + A S GH E
Sbjct: 1676 SPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVS 1735
Query: 317 ------RKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKR 370
+ Q G +G+R G S Q ++ E A P++ G + +
Sbjct: 1736 AHGQAGPHQQSHQESTRGQSGERSGRS-GSFLYQVSTHEQSESAHGRTGPSTGGRQRSRH 1794
Query: 371 KPQQPQRR--------------PAAGTGQRRGSGSSPSADQQRAQDREEEVRKWKKRVDL 416
+ + R P + G R+GS S D ++R D+
Sbjct: 1795 EQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDV 1854
Query: 417 S 417
S
Sbjct: 1855 S 1855
Score = 57.0 bits (136), Expect = 3e-08
Identities = 88/418 (21%), Positives = 155/418 (37%), Gaps = 51/418 (12%)
Query: 34 RPQQQPQCQPAGG-TGQRRGSGSSPSADQQG-AQDREEEAAAAPAADQQRAQDREEEAAA 91
R Q Q Q +G T + +GS S +D QG ++D E + +A A ++ + +
Sbjct: 1896 RHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSR 1955
Query: 92 APVP-----TSSGHRTEKRKRLQLQCQPAGGTGQRRGS--RSSPSADQQRAQDREEEAAA 144
P GH + ++ + + GQ S ++ SA ++ + ++A
Sbjct: 1956 HPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSAD 2015
Query: 145 APVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGA---------QDREEEA 195
+ + GH + R G+ G S +D Q Q +E+
Sbjct: 2016 SSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKES 2075
Query: 196 AAAPAPTSRGHR-------TEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQR---AQDRE 245
A + S G + + + + A TG R+GS + D R +Q+ +
Sbjct: 2076 ARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQ 2135
Query: 246 EEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQR-----------RGSGYSPSADQQGA 294
+ P P SRG R + Q R G+ RG S SA ++
Sbjct: 2136 DTIRGHPGP-SRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRK-T 2193
Query: 295 QDREEEAAAAPAPTSSGHRTEK-----RKRLQLQCQPAGG-TGQRRGSGCSSSANQQG-A 347
D+E+ + S H R L Q Q +G T + RGS S ++ +G +
Sbjct: 2194 YDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHS 2253
Query: 348 QDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREE 405
+D E + +A + + H + + + + R P + R G G S + +Q E
Sbjct: 2254 EDSERRSGSA---SRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAE 2308
Score = 57.0 bits (136), Expect = 3e-08
Identities = 85/403 (21%), Positives = 141/403 (34%), Gaps = 66/403 (16%)
Query: 26 ENEKTKPLRPQQQPQCQPAGGTGQ----RRGSGSSPSADQQGAQDREEEAAAAPAADQQ- 80
++E ++ R Q Q + G R SGS+ + Q++ + P + +
Sbjct: 3201 QSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHED 3260
Query: 81 -----RAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRA 135
+ DR ++ TSSG + Q G+R GSR SAD R
Sbjct: 3261 RAGHGHSADRSRQSGTRHAETSSGGQAASSHE-----QARSSPGERHGSRHQQSADSSRH 3315
Query: 136 QDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEA 195
A++ V SR GS S ++D +G + +
Sbjct: 3316 SGIPRGQASSAVRDSR----------------------HWGSSGSQASDSEGHSEESDTQ 3353
Query: 196 AAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPT 255
+ + + H+ ++ + + +GG R GS Q + + E+A T
Sbjct: 3354 SVSGHGQAGPHQQSHQESARDR---SGGRSGRSGSFL-----YQVSTHEQSESAHGRTRT 3405
Query: 256 SRGHR--TEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHR 313
S G R + + + R A GQ G+ P + ++G Q E + + S H
Sbjct: 3406 STGRRQGSHHEQARDSSRHSASQEGQDTIRGH-PGSSRRGRQGSHYEQSVDRSGHSGSHH 3464
Query: 314 TEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQ 373
+ + G + RG S SA++Q R +E + S H E
Sbjct: 3465 SHTTSQ--------GRSDASRGQSGSRSASRQ---TRNDEQSGDGSRHSWSHHHEASTQA 3513
Query: 374 QPQRRPAAGTGQRRG------SGSSPSADQQRAQDREEEVRKW 410
R +G GQ G GSS S D +Q E+ +W
Sbjct: 3514 DSSRHSQSGQGQSAGPRTSRNQGSSVSQDSD-SQGHSEDSERW 3555
Score = 57.0 bits (136), Expect = 3e-08
Identities = 82/386 (21%), Positives = 138/386 (35%), Gaps = 45/386 (11%)
Query: 34 RPQQQPQCQPAGG-TGQRRGSGSSPSADQQG-AQDREEEAAAAPAADQQRAQDREEEAAA 91
R Q Q Q AG T + +GS S +D QG ++D E + +A + AQ++ + +
Sbjct: 3517 RHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSR 3576
Query: 92 APVP-----TSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSP-SADQQRAQDREEEAAAA 145
P GH E ++ GQ S S+ +R +++A +
Sbjct: 3577 HPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADS 3636
Query: 146 PVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQG-AQDREEEAAAA---PAP 201
+ GH Q A RGS S ++D +G ++D + ++ +A P
Sbjct: 3637 SRHSGIGHG---------QASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGP 3687
Query: 202 TSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRT 261
+ H+ R G R RS Q ++ E A P++ G +
Sbjct: 3688 HQQSHQESTR-----------GRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQG 3736
Query: 262 EKRKP-QQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRL 320
+ + + R A GQ G+ P + + G Q E + + S H + +
Sbjct: 3737 SRHEQARDSSRHSASQEGQDTIRGH-PGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQ- 3794
Query: 321 QLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPA 380
G + G S SA+++ R EE + S E R
Sbjct: 3795 -------GRSDASHGQSGSRSASRE---TRNEEQSGDGSRHSGSRHHEASTQADSSRHSQ 3844
Query: 381 AGTGQRRGSGSSPSADQQRAQDREEE 406
+G G+ GS S +QD + E
Sbjct: 3845 SGQGESAGSRRSRRQGSSVSQDSDSE 3870
Score = 56.6 bits (135), Expect = 4e-08
Identities = 83/401 (20%), Positives = 138/401 (34%), Gaps = 46/401 (11%)
Query: 36 QQQPQCQPAGGTGQRRGSGSSPSADQ-------------QGAQDREEEAAAAPAADQQRA 82
Q + P G R+GS S D+ QG D + + +A +Q
Sbjct: 1162 QDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTR 1221
Query: 83 QDREE-----EAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQD 137
+D++ + + +S + + ++ + T + +GS S +D +R D
Sbjct: 1222 KDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSD 1281
Query: 138 REEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGS-GSSPSADQQGAQDREEEAA 196
E + + SR H R++ + R G + R S G S + +Q E ++
Sbjct: 1282 DSERLSGS---ASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSS 1338
Query: 197 AAPAPTSR-------GHRTEKRKPQQPQCRPAGGTGQRRGS---RSSPSADQQRAQDREE 246
A +S G R R Q G G R+ S R S +Q
Sbjct: 1339 HGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNS 1398
Query: 247 EAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPS-ADQQGAQDREEEAAAAP 305
E + + T + P Q + + SG S S Q + ++ E
Sbjct: 1399 EGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQT 1458
Query: 306 APTSSGH---RTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTS 362
AP++ G R E+ + G RG SS +QG+ +
Sbjct: 1459 APSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQS-------VDR 1511
Query: 363 SGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDR 403
SGH PQ R A GQ SG ++ Q R +++
Sbjct: 1512 SGHSGYHHSHTTPQGRSDASHGQ---SGPRSASRQTRNEEQ 1549
Score = 56.2 bits (134), Expect = 5e-08
Identities = 90/397 (22%), Positives = 143/397 (36%), Gaps = 51/397 (12%)
Query: 52 GSGSSPSADQQG-AQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEK------ 104
GS S ++D +G +++ + ++ + D Q +E A SG R+ +
Sbjct: 1065 GSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESAR-----DWSGGRSGRSGSFIY 1119
Query: 105 RKRLQLQCQPAGG-----TGQRRGSRSSPSADQQR--AQDREEEAAAAPVPTSRGHRTEK 157
+ Q + A G TG+R+GS + D R A ++ A + RG R
Sbjct: 1120 QVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGS 1179
Query: 158 RKRQQPQRRPAGG------TGQRR-----GSGSSPSADQQGAQDREEEAAAAPAPTSRGH 206
Q R G T Q R G S SA +Q +D++ + + SR H
Sbjct: 1180 HHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSG-SRHH 1238
Query: 207 RT-----EKRKPQQPQCRPAGG-TGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHR 260
R Q Q + +G T + +GS S +D +R D E + + SR H
Sbjct: 1239 EAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGS---ASRNHH 1295
Query: 261 TEKRKPQQPQRRPAGGTGQRRGS-GYSPSADQQGAQDREEEAAAA-------PAPTSSGH 312
R+ + R G + R S G+S + +Q E ++ A +S G
Sbjct: 1296 GSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGE 1355
Query: 313 RTEKRKRLQLQCQPAGGTGQRRGSGC---SSSANQQGAQDREEEAAAAPVPTSSGHRTEK 369
R R + G G R+ S S G+Q E + T S +
Sbjct: 1356 RHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQ 1415
Query: 370 RKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEE 406
P Q + +A SG S S Q + + E
Sbjct: 1416 AGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSE 1452
Score = 55.8 bits (133), Expect = 7e-08
Identities = 83/371 (22%), Positives = 128/371 (34%), Gaps = 38/371 (10%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQ-------QRAQDREEEAAAAPV 94
Q G+R GS SAD A++ D +A D E + +
Sbjct: 2969 QARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDT 3028
Query: 95 PTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGH- 153
+ S H + Q G +G+ G S Q ++ E + P++RG
Sbjct: 3029 QSVSAHGQAGSHQQSHQESARGRSGETSG-HSGSFLYQVSTHEQSESSHGWTGPSTRGRQ 3087
Query: 154 --RTEKRKRQQPQRRPAGGTGQR--RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTE 209
R E + Q R A GQ RG S +QG ++ + + H T
Sbjct: 3088 GSRHE--QAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTS 3145
Query: 210 KRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQP 269
+ + + G +G R SR++ + +Q R + A T H R Q
Sbjct: 3146 QGRSDASR----GQSGSRSASRTTRNEEQSGDSSRHSVSRHHEAST---HADISRHSQAV 3198
Query: 270 QRRPAGGTGQRR-GSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAG 328
Q + G RR GS S +D +G + E + + + G E+ + P
Sbjct: 3199 QGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSR--HPRS 3256
Query: 329 GTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRG 388
R G G S+ DR ++ TSSG + Q + G+R G
Sbjct: 3257 HHEDRAGHGHSA--------DRSRQSGTRHAETSSGGQAASSHEQ-----ARSSPGERHG 3303
Query: 389 SGSSPSADQQR 399
S SAD R
Sbjct: 3304 SRHQQSADSSR 3314
Score = 55.8 bits (133), Expect = 7e-08
Identities = 85/377 (22%), Positives = 126/377 (33%), Gaps = 50/377 (13%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQ-------RAQDREEEAAAAPV 94
Q G+R GS SAD A++ D + +A D E + +
Sbjct: 3293 QARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDT 3352
Query: 95 PTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHR 154
+ SGH + Q +G R G S S Q + + E+A TS G R
Sbjct: 3353 QSVSGHGQAGPHQQSHQESARDRSGGRSGR--SGSFLYQVSTHEQSESAHGRTRTSTGRR 3410
Query: 155 TEKRKRQ--QPQRRPAGGTGQR--RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEK 210
Q R A GQ RG S +QG+ + + + + H T +
Sbjct: 3411 QGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQ 3470
Query: 211 RKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 270
G + RG S SA +Q R +E + + S H E
Sbjct: 3471 -----------GRSDASRGQSGSRSASRQT---RNDEQSGDGSRHSWSHHHEASTQADSS 3516
Query: 271 RRPAGGTGQRR--------GSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQL 322
R G GQ GS S +D QG + E + + + G E+ +
Sbjct: 3517 RHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSR--DG 3574
Query: 323 QCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAG 382
P R G G S+ +++Q E ++ +S Q R +A
Sbjct: 3575 SRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASS-----------HEQARSSA- 3622
Query: 383 TGQRRGSGSSPSADQQR 399
G+R GS SAD R
Sbjct: 3623 -GERHGSHHQQSADSSR 3638
Score = 52.8 bits (125), Expect = 6e-07
Identities = 84/388 (21%), Positives = 136/388 (35%), Gaps = 50/388 (12%)
Query: 47 TGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRK 106
+G R SGS S ++ ++D + ++ +A Q +E A TS GH
Sbjct: 2682 SGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETS-GHSGSFLY 2740
Query: 107 RLQLQCQPA---GGTGQ----RRGSRSSPSADQQR---AQDREEEAAAAPVPT------- 149
++ Q G TG R+GSR + D R +QD ++ P +
Sbjct: 2741 QVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGY 2800
Query: 150 -------SRGHRTEKRKRQQPQRRP---AGGTGQRRGSGSSPSADQQGAQDREEEAAAAP 199
S GH Q R G +G R S ++ + +Q G R +
Sbjct: 2801 HHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHE 2860
Query: 200 APTSRGHRTEKRKPQQPQCRPAGGTGQRR-GSRSSPSADQQ-RAQDREEEAAAAPAPTSR 257
A T H R Q Q + G RR GS S +D + ++D E + +A SR
Sbjct: 2861 AST---HADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSA----SR 2913
Query: 258 GHR-TEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAP-------TS 309
H + + + + R P R G G+S + +Q + ++ A +S
Sbjct: 2914 NHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSS 2973
Query: 310 SGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQG-----AQDREEEAAAAPVPTSSG 364
+G R + G G + S + +G A D E + + + S
Sbjct: 2974 AGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSA 3033
Query: 365 HRTEKRKPQQPQRRPAAGTGQRRGSGSS 392
H Q Q +G+ G S
Sbjct: 3034 HGQAGSHQQSHQESARGRSGETSGHSGS 3061
Score = 52.0 bits (123), Expect = 1e-06
Identities = 81/432 (18%), Positives = 147/432 (34%), Gaps = 52/432 (12%)
Query: 6 KEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQ 65
K +D + + +E+ + LE R + + + TG +R SS +++G
Sbjct: 109 KHEDNKQEENKENRKRPSSLERRNN---RKGNKGRSKSPRETGGKRHESSSEKKERKGYS 165
Query: 66 D--REEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ--- 120
REEE ++ +++ E R E+++ + TG+
Sbjct: 166 PTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQ 225
Query: 121 ---RRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQ---- 173
+ G ++ Q A D + R ++ + Q R T Q
Sbjct: 226 KWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQ 285
Query: 174 ------RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQR 227
RRGS S D +G + E + + + G E+ R
Sbjct: 286 ESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQ---------------SR 330
Query: 228 RGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSP 287
GSR S D+ RA ++ + T + + + + G+R GSG+
Sbjct: 331 DGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQ 390
Query: 288 SADQQGAQDREEEAAAAPAPTSSGHRTEKRKRL--------QLQCQPAGGTGQRRGSGCS 339
SAD A+ A + GHR + Q G G+ +G
Sbjct: 391 SAD-SSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGK---AGLR 446
Query: 340 SSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQR 399
++Q+ + R E + +S + +P R TG R+GS + D R
Sbjct: 447 QQSHQESTRGRSGERSGRS-GSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSR 505
Query: 400 ---AQDREEEVR 408
+Q+ ++ +R
Sbjct: 506 HSASQEGQDTIR 517
Score = 52.0 bits (123), Expect = 1e-06
Identities = 84/392 (21%), Positives = 136/392 (34%), Gaps = 71/392 (18%)
Query: 47 TGQRRGSGSSPSADQQG-AQDREEEAAAAPAADQQRAQDREEEAAAAPVP-----TSSGH 100
T + RGS S +D +G ++D E + +A AQ++ + + P GH
Sbjct: 2235 TSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGH 2294
Query: 101 RTEKRKRLQLQCQPAGGTGQRRGSRSSP-SADQQRAQDREEEAAAAPVPTSRGHRTEKRK 159
E ++ GQ S S+ +R +++A + + GH
Sbjct: 2295 SAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHG----- 2349
Query: 160 RQQPQRRPAGGTGQRRGSGSSPSADQQG-AQDREEEAAAA---PAPTSRGHRTEKRKPQQ 215
Q A RGS S ++D +G ++D + ++ +A P + H+ R
Sbjct: 2350 ----QASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRG--- 2402
Query: 216 PQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRG---------------HR 260
R AG +G+ S S Q + + E+A TS G H
Sbjct: 2403 ---RSAGRSGR------SGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHS 2453
Query: 261 TEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQG--AQDREEEAAAAPAPTSSGHRTEKRK 318
T + P +G R+GS Y D+ G + + S GH +
Sbjct: 2454 TSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSA 2513
Query: 319 RLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRR 378
Q + G G R G++ E + A SSGH Q +
Sbjct: 2514 SRQTRNDEQSGDGSR----------HSGSRHHEASSRA----DSSGH-------SQVGQG 2552
Query: 379 PAAGTGQRRGSGSSPSADQQRAQDREEEVRKW 410
+ G R GSS S D +Q E+ +W
Sbjct: 2553 QSEGPRTSRNWGSSFSQDSD-SQGHSEDSERW 2583
Score = 51.6 bits (122), Expect = 1e-06
Identities = 80/407 (19%), Positives = 134/407 (32%), Gaps = 45/407 (11%)
Query: 36 QQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVP 95
QQ Q G +G+R G S + E + R + R E+A
Sbjct: 1744 QQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQAR----- 1798
Query: 96 TSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQ----------RAQDREEEAAAA 145
SS H + + ++ P G R+GS S D +Q+R + +
Sbjct: 1799 DSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQ 1858
Query: 146 PVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQ--------DREEEAAA 197
S +T K+ R +G S + S Q Q R + ++
Sbjct: 1859 SGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSV 1918
Query: 198 APAPTSRGHRTEKRKPQQPQCRPAGGTG---QRRGSRSSPSADQQRAQDREEEAAAAPAP 254
+ S+GH + + R G+ R GSR S + RA ++ +
Sbjct: 1919 SQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSG 1978
Query: 255 TSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRT 314
T + + + + G+R GS + + A+ A SGHR
Sbjct: 1979 TRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRG 2038
Query: 315 EKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGA---QDREEEAAAAPVPTSSGHR----- 366
Q + G S S + Q A Q +E+A SSG
Sbjct: 2039 YSGS------QASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLY 2092
Query: 367 --TEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQR---AQDREEEVR 408
+ + + + A TG R+GS + D R +Q+ ++ +R
Sbjct: 2093 QVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIR 2139
Score = 49.7 bits (117), Expect = 5e-06
Identities = 79/384 (20%), Positives = 136/384 (35%), Gaps = 42/384 (10%)
Query: 47 TGQRRGSGSSPSADQQGAQDREEEAAAA--PAADQQRAQDREEEAAAAPVPTSSGHRTEK 104
+G R SGS S + ++D + ++ +A A Q++ +A SG +
Sbjct: 2358 SGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQ 2417
Query: 105 RKRLQLQCQPAGG-----TGQRRGSRSSPSADQQR---AQDREEEAAAAPVPTSRGHRTE 156
+ Q + A G TG R+GS + D R +Q+ ++ P +S G +
Sbjct: 2418 VSTHE-QSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGS 2476
Query: 157 KRKRQQPQRRPAGG-----TGQRR-----GSGSSPSADQQGAQDREEEAAAAPAPTSRGH 206
++ + +G T Q R G S SA +Q D E+ + SR H
Sbjct: 2477 HYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRND-EQSGDGSRHSGSRHH 2535
Query: 207 RTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDRE-----EEAAAAPAPTSRGHR- 260
R + G GQ G R+S + +QD + E++ SR H
Sbjct: 2536 EASSRADSSGHSQV--GQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHG 2593
Query: 261 TEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAP-------TSSGHR 313
+ + + + R P R G G+S + +Q + ++ A +S+G R
Sbjct: 2594 SAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGER 2653
Query: 314 TEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQG-----AQDREEEAAAAPVPTSSGHRTE 368
+ G G + S + +G A D E + + + S H
Sbjct: 2654 HGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQA 2713
Query: 369 KRKPQQPQRRPAAGTGQRRGSGSS 392
Q Q +G+ G S
Sbjct: 2714 GSHQQSHQESARGRSGETSGHSGS 2737
Score = 47.0 bits (110), Expect = 3e-05
Identities = 72/366 (19%), Positives = 120/366 (32%), Gaps = 27/366 (7%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQ-------QRAQDREEEAAAAPV 94
Q G+R GS SAD A++ D +A D E + +
Sbjct: 3617 QARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDT 3676
Query: 95 PTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHR 154
+ S H + Q + G R RS Q ++ E A P++ G +
Sbjct: 3677 QSVSAHG-QAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQ 3735
Query: 155 TEKRKR-QQPQRRPAGGTGQR--RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKR 211
+ ++ + R A GQ RG S +QG+ + + + + H T +
Sbjct: 3736 GSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQG 3795
Query: 212 KPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQR 271
+ + + R S D R A+ A +S R Q Q
Sbjct: 3796 RSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSS-------RHSQSGQG 3848
Query: 272 RPAGGTGQRR-GSGYSPSADQQG-AQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGG 329
AG RR GS S +D + +D E + +A S H R++ + + G
Sbjct: 3849 ESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESA----SRNHHGSSREQSRDGSRHPGS 3904
Query: 330 TGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRT---EKRKPQQPQRRPAAGTGQR 386
+ + S SS Q + +E + + S + + + P G
Sbjct: 3905 SHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTE 3964
Query: 387 RGSGSS 392
R G S
Sbjct: 3965 RQKGQS 3970
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 63.2 bits (152), Expect = 4e-10
Identities = 87/388 (22%), Positives = 139/388 (35%), Gaps = 45/388 (11%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHR 101
Q +G Q GSG SP Q+G+ R+ + + R+ + + + GH
Sbjct: 1111 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 1170
Query: 102 TEKRKRLQLQCQPAGGTGQ-----RRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTE 156
+ Q G+G + GSRS S+ +R +S G +
Sbjct: 1171 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERH------------GSSSGSSSH 1218
Query: 157 KRKRQQPQRRPAGGTGQRRGSGSSPSADQQG-----AQDREEEAAAAPAPTSRGHRTEKR 211
+ R+ +G Q GSG SPS + G + + + + +SRG +
Sbjct: 1219 YGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRS 1278
Query: 212 KPQQPQCRPAGGTG-----QRRGSRSSPSADQ-------QRAQDREEEAAAAPAPTSRGH 259
+ G+G + GS S Q ++ ++E ++ +S GH
Sbjct: 1279 GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGH 1338
Query: 260 RTEKRKPQQPQRRPAGGTGQR-------RGSGYSPSADQQGAQDREEEAAAAPAPTSSGH 312
R R G+GQ GSG+S S Q G+ ++ + SG
Sbjct: 1339 RGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHG-SGSGQ 1397
Query: 313 RTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKP 372
+ Q +G T GSG SSS Q G+ R +++ SS +
Sbjct: 1398 SSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGS--RSGQSSRGERHGSSSGSSSSYGQ 1455
Query: 373 QQPQRRPAAGTGQR-RGSGSSPSADQQR 399
R + G GQ GSG SPS + R
Sbjct: 1456 HGSGSRQSLGHGQHGSGSGQSPSPSRGR 1483
Score = 58.9 bits (141), Expect = 8e-09
Identities = 84/390 (21%), Positives = 133/390 (34%), Gaps = 49/390 (12%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHR 101
Q +G Q GSG SP Q+G+ R+ + + R+ + + GH
Sbjct: 2051 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHH 2110
Query: 102 TEKRKRLQLQCQPAGGTGQ-----RRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTE 156
+ Q G+G + GSRS S+ +R +S G +
Sbjct: 2111 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERH------------GSSSGSSSR 2158
Query: 157 KRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQP 216
+ R+ +G Q GSG SPS + G+ + S R+ R P +
Sbjct: 2159 YGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHG--SGSGRSSSRGPYES 2216
Query: 217 QCRPAGGTGQRRGSRSSPSADQQ-------------------RAQDREEEAAAAPAPTSR 257
+ + GQ SA Q ++ ++E ++ +S
Sbjct: 2217 RSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSH 2276
Query: 258 GHRTEKRKPQQPQRRPAGGTGQR-------RGSGYSPSADQQGAQDREEEAAAAPAPTSS 310
G + G+GQ GSG+S S Q G+ ++ + S
Sbjct: 2277 GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHG-SGS 2335
Query: 311 GHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKR 370
G + Q +G T GSG SSS Q G+ R +++ SS +
Sbjct: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGS--RSGQSSRGERHGSSSGSSSSY 2393
Query: 371 KPQQPQRRPAAGTGQR-RGSGSSPSADQQR 399
R + G GQ GSG SPS + R
Sbjct: 2394 GQHGSGSRQSLGHGQHGSGSGQSPSPSRGR 2423
Score = 58.2 bits (139), Expect = 1e-08
Identities = 79/377 (20%), Positives = 132/377 (35%), Gaps = 23/377 (6%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHR 101
Q +G Q GSG SP Q+G+ R+ + + R+ + + + GH
Sbjct: 1581 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 1640
Query: 102 TEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQ 161
+ Q G+G G S Q ++ E +++ + G ++
Sbjct: 1641 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG-ERHGSSSRSSSRYGQHGSGSRQS 1699
Query: 162 QPQRRPAGGTGQ-----RRGSGSSPSADQ-QGAQDREEEAAAAPAPTSRGHRTEKRKPQQ 215
R G+GQ R GSG S+ Q ++ P + GH + + +
Sbjct: 1700 SGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHES 1759
Query: 216 PQCRPAGGTGQRRGSRSSPSADQQ-----RAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 270
+ + GS S Q ++ ++E ++ +S G
Sbjct: 1760 GSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSY 1819
Query: 271 RRPAGGTGQR-------RGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQ 323
+ G+GQ GSG+S S Q G+ ++ + SG +
Sbjct: 1820 GQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHG-SGSGQSSGFGHHESSS 1878
Query: 324 CQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGT 383
Q +G T GSG SSS Q G+ R +++ SS + R + G
Sbjct: 1879 WQSSGYTQHGSGSGHSSSYEQHGS--RSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGH 1936
Query: 384 GQR-RGSGSSPSADQQR 399
GQ GSG SPS + R
Sbjct: 1937 GQHGSGSGQSPSPSRGR 1953
Score = 56.2 bits (134), Expect = 5e-08
Identities = 78/380 (20%), Positives = 133/380 (35%), Gaps = 30/380 (7%)
Query: 36 QQQPQCQPAGGTGQRR-GSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPV 94
Q + + + G GQ GSG SP Q+G+ + ++ R+ + +
Sbjct: 402 QHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGY 461
Query: 95 PTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHR 154
+ GH + Q G+G G S Q ++ E + ++A +S G
Sbjct: 462 SSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRG-ERQGSSAGSSSSYGQH 520
Query: 155 TEKRKRQQPQRRPAGGTGQ-------RRGSGSSPSADQ-QGAQDREEEAAAAPAPTSRGH 206
++ R G+GQ R SGS S+ ++ P + GH
Sbjct: 521 GSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGH 580
Query: 207 RTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKP 266
+ Q+ + + G GQ S S Q + ++ + G + +
Sbjct: 581 -SSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQH 639
Query: 267 QQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQP 326
+ + Q GSG SPS + G+ D ++ + SG + + Q
Sbjct: 640 GSGSSQSSRYGQQGSGSGQSPSRGRHGS-DFGHSSSYGQHGSGSGWSSSNGPHGSVSGQ- 697
Query: 327 AGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQ- 385
+ G G + GSG SS +Q G+ SSG+R + Q R G+
Sbjct: 698 SSGFGHKSGSGQSSGYSQHGSGSSH----------SSGYRKHGSRSGQSSRSEQHGSSSG 747
Query: 386 ------RRGSGSSPSADQQR 399
+ GSGS S+ R
Sbjct: 748 LSSSYGQHGSGSHQSSGHGR 767
Score = 54.3 bits (129), Expect = 2e-07
Identities = 81/405 (20%), Positives = 135/405 (33%), Gaps = 61/405 (15%)
Query: 42 QPAGGTGQRRGSGSSPSADQ-------------QGAQDREEEAAAAPAADQQRAQDREEE 88
Q + G R SGSS S Q QG+ R+ + + + +
Sbjct: 266 QSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQH 325
Query: 89 AAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ-----RRGSRSSPSADQQRAQDREEEAA 143
+ + S GH + Q G+GQ + GS S S+ Q + +A+
Sbjct: 326 GSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQAS 385
Query: 144 AAPVPTSRGHRTEKRKRQQPQRRPAGGTGQR--------------RGSGSSPSADQQG-- 187
++ S ++ + + R + G GQ GSG SPS+ Q G
Sbjct: 386 SSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTG 445
Query: 188 ---AQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDR 244
+ + + + GH + + G+G G S Q ++
Sbjct: 446 FGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGE 505
Query: 245 EEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGG------------TGQRRGSGYSPSADQQ 292
+ ++A + + H + R+ R +G +G R+ S Y P
Sbjct: 506 RQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGS 565
Query: 293 GAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREE 352
G ++ P + SGH + + Q +G SG SS+ Q G+ +
Sbjct: 566 G-----RSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 620
Query: 353 EAA---AAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPS 394
+ A SS H Q R G+ GSG SPS
Sbjct: 621 SSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGS----GSGQSPS 661
Score = 54.3 bits (129), Expect = 2e-07
Identities = 82/414 (19%), Positives = 139/414 (33%), Gaps = 41/414 (9%)
Query: 17 ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQR-RGSGSSPSADQQGAQDREEEAAAAP 75
+SS G++ + + Q + + G GQ GSG SPS ++ R +
Sbjct: 2376 QSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP----SRGRHGSGSGQS 2431
Query: 76 AADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRA 135
++ ++ P + SGH + R Q + G GQ S S Q
Sbjct: 2432 SSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQ-SSGYGQHGSSSGHSSTHGQHG 2490
Query: 136 QDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDRE--- 192
+ ++ S G + + + +G Q GSG SP Q+G+ R+
Sbjct: 2491 STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 2550
Query: 193 ---------------EEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSAD 237
+ + + GH + G+G G S
Sbjct: 2551 YGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS 2610
Query: 238 QQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQ-----RRGSGYSPSADQ- 291
Q ++ E +++ + + G + R G+GQ R GSG S+
Sbjct: 2611 GQSSRG-ERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHG 2669
Query: 292 QGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDR- 350
Q ++ P + GH + + + + GSG S Q G+
Sbjct: 2670 QHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQ 2729
Query: 351 ----EEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQ-----RRGSGSSPSA 395
++E ++ +S GHR R AG+GQ R GSGS S+
Sbjct: 2730 SSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSS 2783
Score = 53.5 bits (127), Expect = 3e-07
Identities = 86/393 (21%), Positives = 141/393 (35%), Gaps = 43/393 (10%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHR 101
Q +G Q GSG SPS + G+ + + R+ R + + + G
Sbjct: 1228 QSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQH 1287
Query: 102 TEKRKRLQLQCQPAGGTGQ--RRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRK 159
Q G+G +G S S ++ ++E ++ +S GHR
Sbjct: 1288 ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG---QSSTFDQEGSSTGQSSSYGHRGSGSS 1344
Query: 160 RQQPQRRPAGGTGQ-----RRGSGS--SPSADQQGA-----QDREEEAAAAPAPTSRGHR 207
+ R G+GQ R GSGS S S Q G+ + + + GH
Sbjct: 1345 QSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1404
Query: 208 TEKRKPQQPQCRPAG-GTG-----QRRGSRSSPSADQQRAQDREEEAAA-----APAPTS 256
E Q C G G+G ++ GSRS S+ +R +++ + + S
Sbjct: 1405 -ESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQS 1463
Query: 257 RGHRTEK----RKPQQPQRRPAGGTGQRRGSGYSPSADQQG-AQDREEEAAAAPAPTSSG 311
GH + P + R G+GQ S YSP G + R + + + G
Sbjct: 1464 LGHGQHGSGSGQSPSPSRGRHGSGSGQ--SSSYSPYGSGSGWSSSRGPYESGSSHSSGLG 1521
Query: 312 HRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRK 371
HR + + + G GQ S SS + Q + ++ SSG + +
Sbjct: 1522 HRESRSGQ-------SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQ 1574
Query: 372 PQQPQRRPAAGTGQRRGSGSSPSADQQRAQDRE 404
+ + Q GSG SP Q+ + R+
Sbjct: 1575 HGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ 1607
Score = 52.8 bits (125), Expect = 6e-07
Identities = 83/396 (20%), Positives = 134/396 (33%), Gaps = 63/396 (15%)
Query: 46 GTGQR-RGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEK 104
G GQ GSG SPS ++ R + ++ ++ P + SGH +
Sbjct: 995 GHGQHGSGSGQSPSP----SRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGL 1050
Query: 105 RKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQ 164
R Q + G GQ S S Q + ++ S G + +
Sbjct: 1051 GHRESRSGQ-SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGS 1109
Query: 165 RRPAGGTGQRRGSGSSPSADQQGAQDRE------------------EEAAAAPAPTSRGH 206
+ +G Q GSG SP Q+G+ R+ + + + GH
Sbjct: 1110 SQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGH 1169
Query: 207 RTEKRKPQQPQCRPAGGTGQ-----RRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRT 261
+ G+G + GSRS S+ +R +S G +
Sbjct: 1170 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER------------HGSSSGSSS 1217
Query: 262 EKRKPQQPQRRPAGGTGQRRGSGYSPSADQQG-----AQDREEEAAAAPAPTSSGHRTEK 316
+ R+ +G Q GSG+SPS + G + + + + +S G +
Sbjct: 1218 HYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESR 1277
Query: 317 RKRLQLQCQPAGGTGQR-------RGSGCSSSANQQGAQDR-----EEEAAAAPVPTSSG 364
+ Q G+G GSG S Q G+ ++E ++ +S G
Sbjct: 1278 SGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYG 1337
Query: 365 HRTEKRKPQQPQRRPAAGTGQ-----RRGSGSSPSA 395
HR R AG+GQ R GSGS S+
Sbjct: 1338 HRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSS 1373
Score = 52.4 bits (124), Expect = 8e-07
Identities = 72/385 (18%), Positives = 138/385 (35%), Gaps = 48/385 (12%)
Query: 42 QPAGGTGQ-----RRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPT 96
Q G+GQ + GSGS S+ +Q + + ++ Q + ++ +
Sbjct: 350 QHESGSGQSSGYSKHGSGSGHSS----SQGQHGSTSGQASSSGQHGSSSRQSSSYGQHES 405
Query: 97 SSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTE 156
+S H + + + Q G + GS SPS+ Q +++ P + G+ +
Sbjct: 406 ASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSG-QHGTGFGRSSSSGPYVSGSGYSSG 464
Query: 157 KRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQD-----REEEAAAAPAPTSRGHRTEKR 211
+ +G T GSG S Q G++ E + ++A + +S G
Sbjct: 465 FGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGS 524
Query: 212 KPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQR 271
+ R G+GQ SPS + R + ++++ R+ R P +
Sbjct: 525 RQSLGHSRHGSGSGQ------SPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYE--- 575
Query: 272 RPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGT- 330
G+G G G+ S Q + + +++ + T H + + C G T
Sbjct: 576 ---SGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQ--SSSCGQHGATS 630
Query: 331 GQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTE------------------KRKP 372
GQ G S + Q ++ ++ + + P+ H ++ P
Sbjct: 631 GQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGP 690
Query: 373 QQPQRRPAAGTGQRRGSGSSPSADQ 397
++G G + GSG S Q
Sbjct: 691 HGSVSGQSSGFGHKSGSGQSSGYSQ 715
Score = 52.0 bits (123), Expect = 1e-06
Identities = 86/415 (20%), Positives = 142/415 (34%), Gaps = 43/415 (10%)
Query: 17 ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQR-RGSGSSPSADQQGAQDREEEAAAAP 75
+SS G+Q + + Q + + G GQ GSG SPS ++ R +
Sbjct: 1906 QSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP----SRGRHGSGSGQS 1961
Query: 76 AADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRA 135
++ ++ P + SGH + R Q + G GQ S S Q
Sbjct: 1962 SSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQ-SSGYGQHGSSSGHSSTHGQHG 2020
Query: 136 QDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEA 195
+ ++ S G + + + +G Q GSG SP Q+G+ R+ +
Sbjct: 2021 SASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 2080
Query: 196 AAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEA-----AA 250
S R+ P + G G S S+ Q + +
Sbjct: 2081 YGRHG--SGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS 2138
Query: 251 APAPTSRGHR------TEKRKPQ--QPQRRPAGGTGQRRGSGYSPSADQQG-----AQDR 297
+SRG R + R Q R+ +G Q GSG+SPS + G +
Sbjct: 2139 RSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSH 2198
Query: 298 EEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQR-------RGSGCSSSANQQGAQDR 350
+ + + +S G + + Q G+G GSG S Q G+
Sbjct: 2199 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG 2258
Query: 351 -----EEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQ-----RRGSGSSPSA 395
++E ++ +S G + +G+GQ R GSGS S+
Sbjct: 2259 QSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSS 2313
Score = 51.2 bits (121), Expect = 2e-06
Identities = 81/391 (20%), Positives = 136/391 (34%), Gaps = 39/391 (9%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHR 101
Q +G Q GSG SPS + G+ + + R+ R + + + G
Sbjct: 2168 QSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQH 2227
Query: 102 TEKRKRLQLQCQPAGGTGQ--RRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRK 159
Q G+G +G S S ++ ++E ++ +S G
Sbjct: 2228 ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG---QSSTFDQEGSSTGQSSSHGQHGSGSS 2284
Query: 160 RQQPQRRPAGGTGQ-----RRGSGS--SPSADQQGA-----QDREEEAAAAPAPTSRGHR 207
+ + G+GQ R GSGS S S Q G+ + + + GH
Sbjct: 2285 QSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 2344
Query: 208 TEKRKPQQPQCRPAGGTG-----QRRGSRSSPSADQQRAQDREEEAAA-----APAPTSR 257
+ G+G ++ GSRS S+ +R +++ + + S
Sbjct: 2345 ESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSL 2404
Query: 258 GHRTEK----RKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHR 313
GH + P + R G+GQ S YSP G ++ P + SGH
Sbjct: 2405 GHGQHGSGSGQSPSPSRGRHGSGSGQ--SSSYSPYGSGSGWS-----SSRGPYESGSGHS 2457
Query: 314 TEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQ 373
+ R Q + G GQ S SS + Q + ++ SSG + +
Sbjct: 2458 SGLGHRESRSGQ-SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHG 2516
Query: 374 QPQRRPAAGTGQRRGSGSSPSADQQRAQDRE 404
+ + Q GSG SP Q+ + R+
Sbjct: 2517 SGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ 2547
Score = 50.4 bits (119), Expect = 3e-06
Identities = 72/360 (20%), Positives = 121/360 (33%), Gaps = 33/360 (9%)
Query: 46 GTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKR 105
G+GQ G G S QG + +A+ + Q R +++++ SS ++
Sbjct: 810 GSGQASGFGQHESGSGQGYS--QHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSY 867
Query: 106 KRLQLQCQPAGGTGQR-RGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQ 164
+ + A G G+ GS SP Q R + +P S G R
Sbjct: 868 GQHESASHHASGRGRHGSGSGQSPGHGQ-----RGSGSGQSP---SYGRHGSGSGRSSSS 919
Query: 165 RRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGT 224
R G+GQ G G S+ Q + + + + + + Q + G+
Sbjct: 920 GRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGS 979
Query: 225 GQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSG 284
G S S + +P+P+ H G+G + S
Sbjct: 980 SSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH----------------GSGSGQSSS 1023
Query: 285 YSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQ 344
Y P G ++ P + SGH + R Q + G GQ S SS +
Sbjct: 1024 YGPYRSGSGWS-----SSRGPYESGSGHSSGLGHRESRSGQ-SSGYGQHGSSSGHSSTHG 1077
Query: 345 QGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDRE 404
Q + ++ SSG + + + + Q GSG SP Q+ + R+
Sbjct: 1078 QHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ 1137
Score = 50.1 bits (118), Expect = 4e-06
Identities = 71/336 (21%), Positives = 111/336 (33%), Gaps = 66/336 (19%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHR 101
Q +G Q GSG SP Q+G+ R+ + + R+ + + + GH
Sbjct: 2521 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 2580
Query: 102 TEKRKRLQLQCQPAGGTGQ-----RRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTE 156
+ Q G+G + GSRS S+ +R +S G +
Sbjct: 2581 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERH------------GSSSGSSSH 2628
Query: 157 KRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQP 216
+ R+ +G Q GSG SPS + G+ + S R+ R P +
Sbjct: 2629 YGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHG--SGSGRSSSRGPYES 2686
Query: 217 QCRPAGGTGQRRGSRSSPSADQQ-------------------RAQDREEEAAAAPAPTSR 257
+ + GQ SA Q ++ ++E ++ +S
Sbjct: 2687 RLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSY 2746
Query: 258 GHRTEKRKPQQPQRRPAGGTGQR-------RGSGYSPSADQQGAQDREEEAAAAPAPTSS 310
GHR R G+GQ GSG S S Q G+ + SS
Sbjct: 2747 GHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQ----------SS 2796
Query: 311 GHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQG 346
G+ Q G+GQ S C +N G
Sbjct: 2797 GY-----------SQHGSGSGQDGYSYCKGGSNHDG 2821
Score = 49.3 bits (116), Expect = 6e-06
Identities = 78/388 (20%), Positives = 134/388 (34%), Gaps = 47/388 (12%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHR 101
Q +G T GSG S S +Q G++ + + E+ +++ +S G
Sbjct: 940 QSSGYTQHGSGSGHSSSYEQHGSRSGQSSRS-------------EQHGSSSGSSSSYGQH 986
Query: 102 TEKRKRLQLQCQPAGGTGQ-------RRGSRSSPSADQQRAQDREE-EAAAAPVPTSRGH 153
++ Q G+GQ R GS S S+ + ++ P + GH
Sbjct: 987 GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGH 1046
Query: 154 RTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDRE-----EEAAAAPAPTSRGHRT 208
+ R+ + +G SG S + Q G+ + + A++ +S G
Sbjct: 1047 SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHG 1106
Query: 209 EKRKPQQPQCRPAGGTGQR-------RGSRSSPS-----ADQQRAQDREEEAAAAPAPTS 256
R G+GQ GSR SPS + R+ + + +
Sbjct: 1107 SGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSG 1166
Query: 257 RGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSS-GHRTE 315
GH + Q G+G SGY + G R E ++ +S G
Sbjct: 1167 FGH--HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGS 1224
Query: 316 KRKRLQLQCQPAGGTGQ-----RRGSGCS-SSANQQGAQDREEEAAAAPVPTSSGHRTEK 369
++ + G+G R GSG SS++ Q ++ P + SGH +
Sbjct: 1225 GSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF 1284
Query: 370 RKPQQPQRRPAAGTGQRRGSGSSPSADQ 397
+ + +A + GSG S Q
Sbjct: 1285 GQHESGSGHSSAYSQHGSGSGHFCSQGQ 1312
Score = 48.5 bits (114), Expect = 1e-05
Identities = 70/385 (18%), Positives = 125/385 (32%), Gaps = 42/385 (10%)
Query: 45 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEK 104
G G G SPS + G+ + + + + + R + + + GHR +
Sbjct: 1467 GQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESR 1526
Query: 105 RKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQ 164
+ + G GQ S S Q + ++ S G + +
Sbjct: 1527 SGQ-------SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGS 1579
Query: 165 RRPAGGTGQRRGSGSSPSADQQGAQDRE------------------EEAAAAPAPTSRGH 206
+ +G Q GSG SP Q+G+ R+ + + + GH
Sbjct: 1580 SQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGH 1639
Query: 207 RTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKP 266
+ G+G G S Q ++ E +++ + + G +
Sbjct: 1640 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG-ERHGSSSRSSSRYGQHGSGSRQ 1698
Query: 267 QQPQRRPAGGTGQ-----RRGSGYSPSADQ-QGAQDREEEAAAAPAPTSSGHRTEKRKRL 320
R G+GQ R GSG S+ Q ++ P + SGH + +
Sbjct: 1699 SSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHE 1758
Query: 321 QLQCQPAGGTGQRRGSGCSSSANQQGAQDR-----EEEAAAAPVPTSSGHRTEKRKPQQP 375
+ + GSG S Q G+ ++E ++ +S G
Sbjct: 1759 SGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSS 1818
Query: 376 QRRPAAGTGQ-----RRGSGSSPSA 395
+ +G+GQ R GSGS S+
Sbjct: 1819 YGQQGSGSGQSPSRGRHGSGSGHSS 1843
Score = 48.1 bits (113), Expect = 1e-05
Identities = 85/417 (20%), Positives = 144/417 (34%), Gaps = 40/417 (9%)
Query: 17 ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTG-QRRGSGSSPSADQQGAQDREEEAAAAP 75
+SS G++ + ++ Q + + G G Q GSG SPS + G+ +
Sbjct: 1672 QSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQH 1731
Query: 76 AADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ--RRGSRSSPSADQQ 133
+ R+ R + + + G Q G+G +G S S
Sbjct: 1732 GSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG--- 1788
Query: 134 RAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQ-----RRGSGS--SPSADQQ 186
++ ++E ++ +S G + + G+GQ R GSGS S S Q
Sbjct: 1789 QSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQH 1848
Query: 187 GA-----QDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTG-----QRRGSRSSPSA 236
G+ + + + GH + G+G ++ GSRS S+
Sbjct: 1849 GSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSS 1908
Query: 237 --DQQRAQDREEEAAAAPAPTSR---GHRTEK----RKPQQPQRRPAGGTGQRRGSGYSP 287
+Q + + SR GH + P + R G+GQ S Y P
Sbjct: 1909 RGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ--SSSYGP 1966
Query: 288 SADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGA 347
G ++ P + SGH + R Q +G SG SS+ Q G+
Sbjct: 1967 YGSGSGWS-----SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS 2021
Query: 348 QDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDRE 404
+ + SSG + + + + Q GSG SP Q+ + R+
Sbjct: 2022 ASGQSSSCGQH-GASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ 2077
Score = 42.7 bits (99), Expect = 6e-04
Identities = 84/446 (18%), Positives = 146/446 (32%), Gaps = 61/446 (13%)
Query: 5 QKEQDTRLRKLRESS-EGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG 63
Q+E + K +ESS W E R + +P + RR S + Q
Sbjct: 112 QEETEKEENKRQESSFSHSSWSAGENDSYSR-NVRGSLKPGTESISRRLSFQRDFSGQHN 170
Query: 64 AQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRG 123
+ + + +D ++ R + + + + G + G+GQ G
Sbjct: 171 SYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSG 230
Query: 124 SRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSA 183
S+ Q + + + + GH + + + + G R SGSS S
Sbjct: 231 FSQHKSSSGQSSGYSQHGSGS-------GHSSGYGQHGSRSGQSSRGERHRSSSGSSSSY 283
Query: 184 DQQGAQDRE-------------------------------EEAAAAPAPTSRGHRTEKRK 212
Q G+ R+ + + + SRGH
Sbjct: 284 GQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSG 343
Query: 213 PQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKP------ 266
+ G+GQ G S + + + + A +S H + R+
Sbjct: 344 QTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQH 403
Query: 267 QQPQRRPAG------------GTGQR-RGSGYSPSADQQGAQDREEEAAAAPAPTSSGHR 313
+ R +G G GQR GSG SPS+ Q G +++ P + SG+
Sbjct: 404 ESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGT-GFGRSSSSGPYVSGSGYS 462
Query: 314 TEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQ 373
+ +G T GSG SS Q G++ + +S+G + +
Sbjct: 463 SGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQ-GSSAGSSSSYGQHG 521
Query: 374 QPQRRPAAGTGQRRGSGSSPSADQQR 399
R+ + GSG SPS + R
Sbjct: 522 SGSRQSLGHSRHGSGSGQSPSPSRGR 547
Score = 37.4 bits (85), Expect = 0.025
Identities = 57/251 (22%), Positives = 90/251 (35%), Gaps = 30/251 (11%)
Query: 154 RTEKRKRQQPQRRPAGGTGQRRGSG---SSPSADQQGAQDREEEAAAAPAPTSRGHRTEK 210
R + + Q+ Q +R+ S SS SA + + R + P S R
Sbjct: 102 RDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSF 161
Query: 211 RKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 270
++ Q G G ++S S Q + + + + +P H + Q
Sbjct: 162 QRDFSGQHNSYSGQSSSYGEQNSDS--HQSSGRGQCGSGSGQSPNYGQHGSGSG---QSS 216
Query: 271 RRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGT 330
G+G + SG+S G + + + + SGH + + Q + G
Sbjct: 217 SNDTHGSGSGQSSGFSQHKSSSG-----QSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGE 271
Query: 331 GQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGH-RTEKRKPQQPQR-RPAAGTGQ--- 385
R SG SSS Q G+ R+ S GH R Q P R +G+G
Sbjct: 272 RHRSSSGSSSSYGQHGSGSRQ----------SLGHGRQGSGSRQSPSHVRHGSGSGHSSS 321
Query: 386 --RRGSGSSPS 394
+ GSGSS S
Sbjct: 322 HGQHGSGSSYS 332
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 63.2 bits (152), Expect = 4e-10
Identities = 76/385 (19%), Positives = 142/385 (36%), Gaps = 32/385 (8%)
Query: 2 KPRQKEQDTRLRKLRE-SSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
K R +++D + R+ E ++ + E+ + ++ Q + T + G D
Sbjct: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144
Query: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ 120
Q ++R+ +A R + R+ E +R E+R+R + Q + T
Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRER-ERQREKENKTED 203
Query: 121 RRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSS 180
R R ++ + E R +TE+ + +Q +R A R
Sbjct: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263
Query: 181 PSADQQGAQDREEEAAAAPAPTSRGHRTEK-RKPQQPQCRPAGGTGQRRGSRSSPSADQQ 239
D+ +DR ++ R RTE+ R+ ++ + R +R +R +++
Sbjct: 264 RERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNR---KRERE 320
Query: 240 RAQDREEEAAAAPAPTSRGHRTEKRKPQ----QPQRRPAGGTGQR---RGSGYSPSADQQ 292
R ++RE E R KRK Q + + R G G+R R D+Q
Sbjct: 321 RERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQ 380
Query: 293 GAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREE 352
A++REE E+ + Q + T + R + ++ +DRE
Sbjct: 381 SAREREER--------------ERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRES 426
Query: 353 EAAAAPVPTSSGHRTEKRKPQQPQR 377
E G EK+K ++ R
Sbjct: 427 ERG-----RERGREREKQKGRERDR 446
Score = 56.2 bits (134), Expect = 5e-08
Identities = 72/414 (17%), Positives = 157/414 (37%), Gaps = 60/414 (14%)
Query: 2 KPRQKEQDTR--LRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSA 59
+P +E R L + + ++GD N + + R +++ Q +
Sbjct: 30 RPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTER--------------ET 75
Query: 60 DQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTG 119
D++ + RE++ ++R +DRE+E R ++R R + + + G
Sbjct: 76 DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135
Query: 120 QRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGS 179
+R R + D QR ++R+ +A EK + +Q R T + R
Sbjct: 136 ERGRDRQT---DGQRERERQRDA-------------EKERERQTDRERQRQTERNRQKER 179
Query: 180 SPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQ 239
++Q ++RE + + ++TE R ++ G + R + +++
Sbjct: 180 EREKNRQERRERERQR-------EKENKTEDRHSER-------GRERERERETETETERK 225
Query: 240 RAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREE 299
R DRE + R +TE+ + +Q +R A R D+ +DR +
Sbjct: 226 RQTDRERD---------RQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQ 276
Query: 300 EAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPV 359
+ RTE+ + + + + + R ++ ++RE +
Sbjct: 277 KERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERD 336
Query: 360 PTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEEVRKWKKR 413
R KR+ + + R ++ G A+++R ++RE + + ++R
Sbjct: 337 REKERERKRKRQTEMDRER-----NRQTGREGRRQAERERERERERDRQSARER 385
Score = 51.2 bits (121), Expect = 2e-06
Identities = 67/310 (21%), Positives = 120/310 (38%), Gaps = 36/310 (11%)
Query: 5 QKEQDTRLRKLRESSEGDQWLENEKTKPL---RPQQQPQCQPAGGTGQRRGSGSSPSADQ 61
+++Q R R +E D+ E E+ + R Q++ + Q +R +
Sbjct: 242 REKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKR 301
Query: 62 QGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQR 121
+ ++RE E +++R ++RE E R KRKR Q + ++
Sbjct: 302 ERQRERERERERNRKRERERERERERERQRETERDREKERERKRKR---QTEMDRERNRQ 358
Query: 122 RGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSP 181
G A+++R ++RE + +A R R R RQ+ + R T + R
Sbjct: 359 TGREGRRQAERERERERERDRQSAREREER-ERDRDRDRQKERERQ---TEKDRDGQRET 414
Query: 182 SADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQR---------RGSRS 232
++ +DRE E + +R ++ R AG +R R +RS
Sbjct: 415 EKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARS 474
Query: 233 S--------PSADQQRAQDREEEAAAA-------PAPTSRGHRTEKRK--PQQPQRRPAG 275
P+ + E+ AA+ PA SRG +R+ P+ ++R G
Sbjct: 475 GVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQG 534
Query: 276 GTGQRRGSGY 285
G G+R G+
Sbjct: 535 GEGRRPSGGF 544
Score = 49.7 bits (117), Expect = 5e-06
Identities = 74/408 (18%), Positives = 152/408 (37%), Gaps = 66/408 (16%)
Query: 2 KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQ 61
K RQ+ ++ ++ +E+ D+ E + + + + + + T + R ++
Sbjct: 183 KNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERER 242
Query: 62 QGAQDREEEAAAAPAADQQRAQ----DREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGG 117
+ +RE + D++R + DR+ + R +K + Q
Sbjct: 243 EKQAERERASERETERDKERERERDRDRDRD------------RRQKERERQ-------- 282
Query: 118 TGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGS 177
T ++R R+ + +R ++R+ E + R +R+R++ ++R T + R
Sbjct: 283 TDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRE---TERDREK 339
Query: 178 GSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSAD 237
+Q DRE + R +R+ ++ R+ +R +
Sbjct: 340 ERERKRKRQTEMDRERNRQTGREGRRQAERERERERER----------DRQSAREREERE 389
Query: 238 QQRAQDREEEAAAAPAPTSRGHR-TEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQD 296
+ R +DR++E G R TEK++ ++ R G+ RG ++ ++
Sbjct: 390 RDRDRDRQKERERQTEKDRDGQRETEKQREREKDRE--SERGRERGREREKQKGRERDRE 447
Query: 297 REEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQ-----QGAQDRE 351
R+ + A +RKR L P T R S N+ + E
Sbjct: 448 RQTDRQAG----------RQRKRSTLYVNPPPRTA--RSGVVQSDPNRPTRGIRWKSSPE 495
Query: 352 EEAAAA-------PVPTSSGHRTEKRK--PQQPQRRPAAGTGQRRGSG 390
+ AA+ P S G +R+ P+ ++R G G+R G
Sbjct: 496 DPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRRPSGG 543
Score = 43.9 bits (102), Expect = 3e-04
Identities = 49/243 (20%), Positives = 90/243 (37%), Gaps = 9/243 (3%)
Query: 174 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRS- 232
RR GS S ++G ++A +R E+R+ ++ R +RR +
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
Query: 233 --SPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSAD 290
++R +DRE+E R ++R Q+ + R G+R G D
Sbjct: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGER---GRDRQTD 144
Query: 291 QQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDR 350
Q ++R+ +A + R + +R + + + Q R + +DR
Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR 204
Query: 351 EEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEEVRKW 410
E +RK Q + R +R A+++RA +RE E K
Sbjct: 205 HSERGRERERERETETETERKRQTDRERDRQRKTERE---REKQAERERASERETERDKE 261
Query: 411 KKR 413
++R
Sbjct: 262 RER 264
Score = 39.3 bits (90), Expect = 0.007
Identities = 46/202 (22%), Positives = 80/202 (39%), Gaps = 38/202 (18%)
Query: 2 KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQ 61
+ R++E+D + + RE E D+ + +K + + ++ Q T ++R +++
Sbjct: 371 RERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRE--TEKQREREKDRESER 428
Query: 62 QGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQR 121
+ RE E D++R DR+ +RKR L P T +
Sbjct: 429 GRERGREREKQKGRERDRERQTDRQAG--------------RQRKRSTLYVNPPPRTARS 474
Query: 122 RGSRSSPSADQQ--RAQDREEEAAAA--------PVPTSRGHRTEKRKRQQPQ------- 164
+S P+ + R + E+ AA P SRG R R+R +P+
Sbjct: 475 GVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRG-RVAGRRRWEPRLGEKRGQ 533
Query: 165 ----RRPAGGTGQRRGSGSSPS 182
RRP+GG G +PS
Sbjct: 534 GGEGRRPSGGFGTENPLSQAPS 555
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 62.0 bits (149), Expect = 1e-09
Identities = 78/329 (23%), Positives = 127/329 (38%), Gaps = 22/329 (6%)
Query: 52 GSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQ 111
G+ P G + EE P + + A A PT + T + L
Sbjct: 376 GAALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQPLPQP 435
Query: 112 CQPAGGTGQRRGSRSSPSADQQRAQ-DREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGG 170
P G S + S + Q D E A A P SR + R++ QRR
Sbjct: 436 PAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKILTQRR---- 491
Query: 171 TGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGS 230
R SPS A AAAA PT + R E+++ + + + +G +
Sbjct: 492 ---ERYRQRSPSPAPAPAP-----AAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAP 543
Query: 231 RSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRR-GSGYSPSA 289
+ S + + + A +S R+ R + RR + T +RR GS S S
Sbjct: 544 PAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSR 603
Query: 290 DQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQD 349
+++ R +A+P P +S + +R+R + + + GG+ +++ S + G
Sbjct: 604 EKR----RRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSG-DG 658
Query: 350 REEEAAAAPVP---TSSGHRTEKRKPQQP 375
E+ A AP P TS G R +R+ P
Sbjct: 659 SEKAPAPAPPPSGSTSCGDRDSRRRGAVP 687
Score = 52.4 bits (124), Expect = 8e-07
Identities = 77/353 (21%), Positives = 137/353 (38%), Gaps = 62/353 (17%)
Query: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPL-----RPQQQPQCQPAGGTGQRRGSGSSPS 58
R++++ ++ SS G Q P R + + A + +RR S S
Sbjct: 521 RERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRS 580
Query: 59 ADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGT 118
+ + + R + R +A+P P +S + +R+R + + + GG+
Sbjct: 581 RSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGS 640
Query: 119 GQRRGSRSSPSADQQRAQDREEEA-AAAPVP---TSRGHRTEKRKRQQPQRRPAGGTGQR 174
+++ + S S ++R+ D E+A A AP P TS G R +R+ P P+
Sbjct: 641 KKKK--KRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVP---PSIQDLTD 695
Query: 175 RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSP 234
+ G D+ + +PAP S R + G +G+ RG +SS
Sbjct: 696 HDLFAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSE-------GLSGEERGGKSS- 747
Query: 235 SADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGA 294
+DR AA+ + +SR ++ RR A G R D+
Sbjct: 748 ------QKDRRRSGAASSSSSSR---------EKGSRRKALDGGDR---------DRDRD 783
Query: 295 QDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQR----RGSGCSSSAN 343
+DR+ + R+ K+ R + P+ G + GSG SSS++
Sbjct: 784 RDRDRD------------RSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSS 824
Score = 48.5 bits (114), Expect = 1e-05
Identities = 90/432 (20%), Positives = 158/432 (36%), Gaps = 69/432 (15%)
Query: 32 PLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAAD-QQRAQDREEEAA 90
P Q+ +P G SP +++ ++ EEE + ++ R E
Sbjct: 242 PAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISETL 301
Query: 91 AAPVPTSS------GHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQR-------AQD 137
A +S G + + Q PA GT + S + A ++R A+
Sbjct: 302 AGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEA 361
Query: 138 REEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQD--REEEA 195
E + V T+ G P P G + G P + + A R
Sbjct: 362 CREGKVSVEVVTAGG------AALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGR 415
Query: 196 AAAPAPTSRGHRTEKRKPQQPQCR-PAG-----------GTGQRR-----GSRSSPSAD- 237
AA P P + T + PQ P R P G G G + + + P+AD
Sbjct: 416 AARPTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADS 475
Query: 238 -------------QQRAQDREEEAAAAPAP---TSRGHRTEKRKPQQPQRRPAGGTGQRR 281
Q+R + R+ + APAP + G T K+ ++ +R
Sbjct: 476 RWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASS 535
Query: 282 GSGYSPSA-------DQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRR 334
SG P+ D + + R+ + + A +S+ R+ R R + + + T +RR
Sbjct: 536 SSGTQPAPPAPASPWDSKKHRSRDRK-PGSHASSSARRRSRSRSRSRSTRRRSRSTDRRR 594
Query: 335 GSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPS 394
G S + + + R +A+P P +S + +R+ + + R G G ++ S S
Sbjct: 595 GGSRRSRSRE---KRRRRRRSASPPPATSSSSSSRRERHRGKHRD--GGGSKKKKKRSRS 649
Query: 395 ADQQRAQDREEE 406
++R+ D E+
Sbjct: 650 RGEKRSGDGSEK 661
Score = 33.9 bits (76), Expect = 0.28
Identities = 49/208 (23%), Positives = 77/208 (37%), Gaps = 43/208 (20%)
Query: 29 KTKPLRPQQQPQCQPAGGTGQRRGSGS---------SPSADQQGAQDR----EEEAAAAP 75
KTKP + +++ + GG+G G S S +A +GA++ EE AA P
Sbjct: 917 KTKPSKTRKK--VRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVP 974
Query: 76 AADQQRAQDREEEAAAAPVPTSSGHRTEKR-KRLQLQCQPAGGTGQRRGSRSSPSADQQR 134
+ +A A P T + K ++ P T + G R +++
Sbjct: 975 STPPPKA------APPPPALTPDSQTVDSSCKTPEVSFLPEEAT-EEAGVRGGAEEEEEE 1027
Query: 135 AQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEE 194
++ EEE E+ + QQP A T S ++PSA +
Sbjct: 1028 EEEEEEE--------------EEEEEQQPATTTATSTAAAAPS-TAPSAGSTAG-----D 1067
Query: 195 AAAAPAPTSRGHRTEKRKPQQPQCRPAG 222
+ A P SR + P P PAG
Sbjct: 1068 SGAEDGPASRVSQLPTLPPPMPWNLPAG 1095
Score = 30.0 bits (66), Expect = 4.1
Identities = 64/335 (19%), Positives = 114/335 (34%), Gaps = 71/335 (21%)
Query: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG 63
R+K D R + D+ ++K +P + + P P GSGSS S+
Sbjct: 769 RRKALDGGDRDRDRDRDRDRDRSSKKARPPK-ESAPSSGPPPKPPVSSGSGSSSSSSSCS 827
Query: 64 AQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRG 123
++ + ++ A + + + AA+ S G + + + +
Sbjct: 828 SRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEM 887
Query: 124 SRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGS---- 179
++++P + + + + +A A ++G + R++ R GG+G G S
Sbjct: 888 AKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKV--RSGGGSGGSGGQVSLKKS 945
Query: 180 -----SPSADQQGAQDR----EEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGT------ 224
S +A +GA++ EE AA P+ K P P P T
Sbjct: 946 KADSCSQAAGTKGAEETSWSGEERAAKVPSTPP-----PKAAPPPPALTPDSQTVDSSCK 1000
Query: 225 ---------------GQRRGSRSSPSADQQRAQDREEE------------AAAAPA---- 253
G R G+ +++ ++ EEE AAAAP+
Sbjct: 1001 TPEVSFLPEEATEEAGVRGGAEEEEEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPS 1060
Query: 254 -------------PTSRGHRTEKRKPQQPQRRPAG 275
P SR + P P PAG
Sbjct: 1061 AGSTAGDSGAEDGPASRVSQLPTLPPPMPWNLPAG 1095
>gi|153070260 myristoylated alanine-rich protein kinase C substrate
[Homo sapiens]
Length = 332
Score = 61.2 bits (147), Expect = 2e-09
Identities = 71/297 (23%), Positives = 118/297 (39%), Gaps = 29/297 (9%)
Query: 39 PQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSS 98
P +G + + +GS+P+AD +EE AAA A A ++ E AAAA P +
Sbjct: 47 PAAAESGAKEELQANGSAPAAD------KEEPAAAGSGAASPSAAEKGEPAAAA-APEAG 99
Query: 99 GHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKR 158
EK + + G G +S ++ + E A P P++ + +K+
Sbjct: 100 ASPVEKEAPAEGEAAEPGSPTAAEGEAASAASS---TSSPKAEDGATPSPSNETPKKKKK 156
Query: 159 KRQQPQRRPAGGTG---QRRGSGSSPSADQQGAQDREEEAA--AAPAPTSRGHRTEKRKP 213
+ + G ++ +G A+ A+ ++EAA AA A G + ++
Sbjct: 157 RFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQ-- 214
Query: 214 QQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAP-APTSRGHRTEKRKPQQPQRR 272
A G G + D Q A + +EAA AP P + +P + + +
Sbjct: 215 -----AAAPGEEAAAGEEGAAGGDPQEA--KPQEAAVAPEKPPASDETKAAEEPSKVEEK 267
Query: 273 PAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAP---TSSGHRTEKRKRLQLQCQP 326
A G + +PSA GA E+EAA A P +S + Q +C P
Sbjct: 268 KAEEAGASAAACEAPSAAGPGAPP-EQEAAPAEEPAAAAASSACAAPSQEAQPECSP 323
Score = 58.9 bits (141), Expect = 8e-09
Identities = 76/338 (22%), Positives = 132/338 (39%), Gaps = 60/338 (17%)
Query: 76 AADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGG-TGQRRGSRSSPSADQQR 134
AA + A +R EAA A P+ + + ++ PA +G + +++ SA
Sbjct: 9 AAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAP--- 65
Query: 135 AQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSG-SSPSADQQGAQDREE 193
A D+EE AAA GSG +SPSA ++G
Sbjct: 66 AADKEEPAAA-------------------------------GSGAASPSAAEKG------ 88
Query: 194 EAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPA 253
E AAA AP + EK P + + G G +S ++ + E A P+
Sbjct: 89 EPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASS---TSSPKAEDGATPS 145
Query: 254 PTSRGHRTEKRKPQQPQRRPAGGTG---QRRGSGYSPSADQQGAQDREEEAA--AAPAPT 308
P++ + +K++ + G ++ +G A+ A+ ++EAA AA A
Sbjct: 146 PSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAA 205
Query: 309 SSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAP-VPTSSGHRT 367
+G + ++ A G+ +G +A + + +EAA AP P +S
Sbjct: 206 EAGAASGEQ---------AAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETK 256
Query: 368 EKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREE 405
+P + + + A G + +PSA A +E
Sbjct: 257 AAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQE 294
Score = 38.1 bits (87), Expect = 0.015
Identities = 34/134 (25%), Positives = 51/134 (38%), Gaps = 7/134 (5%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAP-VPTSSGH 100
+ AGG + S +Q A E A AA + + +EAA AP P +S
Sbjct: 195 EAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDE 254
Query: 101 RTEKRKRLQLQCQPAGGTGQRRGSRSSPSA------DQQRAQDREEEAAAAPVPTSRGHR 154
+ +++ + A G + +PSA +Q A EE AAAA
Sbjct: 255 TKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPS 314
Query: 155 TEKRKRQQPQRRPA 168
E + P+ PA
Sbjct: 315 QEAQPECSPEAPPA 328
Score = 37.7 bits (86), Expect = 0.019
Identities = 32/152 (21%), Positives = 59/152 (38%), Gaps = 8/152 (5%)
Query: 52 GSGSSPSADQQGAQDREEEAAAAPAADQQRAQDRE-----EEAAAAPVPTSSGHRTE-KR 105
G +P+A+ G +D AAA AA+ A + EEAAA + G E K
Sbjct: 182 GEAEAPAAE--GGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKP 239
Query: 106 KRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQR 165
+ + + + + + + ++++A++ AAA P++ G + P
Sbjct: 240 QEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAE 299
Query: 166 RPAGGTGQRRGSGSSPSADQQGAQDREEEAAA 197
PA + S A + + + AA
Sbjct: 300 EPAAAAASSACAAPSQEAQPECSPEAPPAEAA 331
Score = 35.8 bits (81), Expect = 0.074
Identities = 49/190 (25%), Positives = 71/190 (37%), Gaps = 47/190 (24%)
Query: 232 SSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQ 291
S +A + A +R EAA A +P+ K Q+ G SP+A +
Sbjct: 6 SKTAAKGEAAAERPGEAAVASSPS-------KANGQENGHVKVNGDA-------SPAAAE 51
Query: 292 QGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSS-SANQQGAQDR 350
GA++ + +APA +PA GSG +S SA ++G
Sbjct: 52 SGAKEELQANGSAPAADKE--------------EPAAA-----GSGAASPSAAEKG---- 88
Query: 351 EEEAAAAPVPTSSGHRTEKRKPQQPQR----RPAAGTGQ---RRGSGSSPSADQQRAQDR 403
E AAA P + EK P + + P A G+ S SSP A+
Sbjct: 89 --EPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSP 146
Query: 404 EEEVRKWKKR 413
E K KK+
Sbjct: 147 SNETPKKKKK 156
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 61.2 bits (147), Expect = 2e-09
Identities = 61/396 (15%), Positives = 128/396 (32%), Gaps = 14/396 (3%)
Query: 18 SSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAA 77
SS + W + E+ K + + + G +R G G A+++ + R+ E
Sbjct: 663 SSGAEHWQDEEREKGEKDKGR-------GEMERPGEGEKELAEKEEWKKRDGEEQEQKER 715
Query: 78 DQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQD 137
+Q ++R +E E+ R + + + G + G +++ +
Sbjct: 716 EQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGER 775
Query: 138 REEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAA 197
++EE A +G + + + G + G ++G +REEE
Sbjct: 776 KKEERAGKE---EKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEE 832
Query: 198 APAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSR 257
G E+ + + G + ++ + EEE
Sbjct: 833 GEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGE 892
Query: 258 GHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKR 317
G E+ + + G + G G ++G + EEE G E+
Sbjct: 893 GEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEE 952
Query: 318 KRLQLQCQPAGGTGQRRGSGCSSSANQQGAQD----REEEAAAAPVPTSSGHRTEKRKPQ 373
+ + + G G+ G G +G ++ EE G E+ + +
Sbjct: 953 GEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGE 1012
Query: 374 QPQRRPAAGTGQRRGSGSSPSADQQRAQDREEEVRK 409
+ G+ G +++ ++ EE K
Sbjct: 1013 GEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREK 1048
>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform c [Homo sapiens]
Length = 1462
Score = 60.1 bits (144), Expect = 4e-09
Identities = 83/318 (26%), Positives = 121/318 (38%), Gaps = 42/318 (13%)
Query: 21 GDQWLE--NEKTKPLRPQQQPQCQPAGGTGQR----RGSGSSPSADQQGAQDREEEAAAA 74
GD+ LE E TK ++ + + GG R RG GS P D + DR A
Sbjct: 1167 GDEILEINGETTKNMKHSRAIELIKNGGRRVRLFLKRGDGSVPEYDP--SSDRHGPATGP 1224
Query: 75 PAADQQRA-QDREE----EAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPS 129
+ RA DR + E++ P S EKR + G R SR
Sbjct: 1225 QGVPEVRAGPDRRQHPSLESSYPPDLHKSSPHGEKRAHAR------DPKGSREYSRQPNE 1278
Query: 130 ADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQ 189
R+ ++ A P R E R+ Q +R A +RR SP +
Sbjct: 1279 HHTWNGTSRKPDSGACR-PKDRA--PEGRRDAQAERAAAANGPKRR----SP-------E 1324
Query: 190 DREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRG---SRSSPSADQQRAQDREE 246
R E +A R + EKR+ P+ R +RR SR S ++ Q R
Sbjct: 1325 KRREGTRSADNTLERREKHEKRRDVSPERRRERSPTRRRDGSPSRRRRSLERLLEQRRSP 1384
Query: 247 EAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPA 306
E +P R T++R+ + P+RR +R D+ ++REE A
Sbjct: 1385 ERRRGGSPERRAKSTDRRRARSPERRRERSLDKRNRE------DRASHREREEANLKQDA 1438
Query: 307 PTSSGHRTEKRKRLQLQC 324
SS H E+R+R +C
Sbjct: 1439 GRSSRHPPEQRRRPYKEC 1456
Score = 32.7 bits (73), Expect = 0.63
Identities = 53/240 (22%), Positives = 84/240 (35%), Gaps = 55/240 (22%)
Query: 174 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSS 233
+RG GS P D P+S H P+ R Q SS
Sbjct: 1202 KRGDGSVPEYD----------------PSSDRHGPATGPQGVPEVRAGPDRRQHPSLESS 1245
Query: 234 PSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQG 293
D ++ E+ A A P +G R R+P + GT ++ SG D+
Sbjct: 1246 YPPDLHKSSPHGEKRAHARDP--KGSREYSRQPNE--HHTWNGTSRKPDSGACRPKDRAP 1301
Query: 294 AQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEE 353
R+ +A A A R+ +++R G S+ N +++ E
Sbjct: 1302 EGRRDAQAERAAAANGPKRRSPEKRR----------------EGTRSADNTLERREKHE- 1344
Query: 354 AAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEEVRKWKKR 413
KR+ P+RR +RR SPS ++R+ +R E R+ +R
Sbjct: 1345 ---------------KRRDVSPERRRERSPTRRR--DGSPSR-RRRSLERLLEQRRSPER 1386
Score = 30.8 bits (68), Expect = 2.4
Identities = 25/113 (22%), Positives = 44/113 (38%), Gaps = 5/113 (4%)
Query: 5 QKEQDTRLRKLRESS-----EGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSA 59
+K +D + RE S +G + L Q++ + GG+ +RR +
Sbjct: 1344 EKRRDVSPERRRERSPTRRRDGSPSRRRRSLERLLEQRRSPERRRGGSPERRAKSTDRRR 1403
Query: 60 DQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQC 112
+ + RE D+ ++REE SS H E+R+R +C
Sbjct: 1404 ARSPERRRERSLDKRNREDRASHREREEANLKQDAGRSSRHPPEQRRRPYKEC 1456
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 59.7 bits (143), Expect = 5e-09
Identities = 84/368 (22%), Positives = 132/368 (35%), Gaps = 73/368 (19%)
Query: 39 PQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSS 98
PQ Q GG G G G +P + + + E+ A +AA T+
Sbjct: 124 PQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGA------------SAATAATA- 170
Query: 99 GHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKR 158
AGGTG GS +S S Q+R + E R R+
Sbjct: 171 ----------------AGGTGGSGGSPASSSGTQRRGEGSERR-------PRRDRRSSSG 207
Query: 159 KRQQPQRRPAGGTGQRRGSGSSPSADQ--QGAQDREEEAAAAPAPTSRGHRTEKRKPQQP 216
+ ++ R GQR GS +S S + ++R E A + + +S G R
Sbjct: 208 RSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRR--------- 258
Query: 217 QCRPAGGTGQRRGSRSSPSADQQRAQDR-EEEAAAAPAPTSRGHRTEKRKPQQPQRR--- 272
+ A T SR + R++ + +E +A + +R +K +P+ +RR
Sbjct: 259 --KSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSL 316
Query: 273 -PAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTG 331
P GG R S S A Q + +P+P G R+ L P+ +
Sbjct: 317 SPLGG---RDDSPVSHRASQ------SLRSRKSPSPAGGGSSPYSRR---LPRSPSPYSR 364
Query: 332 QRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGS 391
+R S S+ ++G +P P SS R P P R + + R S
Sbjct: 365 RRSPSYSRHSSYERGGD-------VSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSS 417
Query: 392 SPSADQQR 399
S + R
Sbjct: 418 RHSRSRSR 425
Score = 53.5 bits (127), Expect = 3e-07
Identities = 66/265 (24%), Positives = 102/265 (38%), Gaps = 62/265 (23%)
Query: 152 GHRTEKRKR-QQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEE------AAAAPAPTSR 204
G EKR+ PQ + GG G G G +P + + + E+ A+AA A T+
Sbjct: 112 GQEAEKRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATA- 170
Query: 205 GHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKR 264
AGGTG GS +S S Q+R + E R R+
Sbjct: 171 ----------------AGGTGGSGGSPASSSGTQRRGEGSERR-------PRRDRRSSSG 207
Query: 265 KPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQC 324
+ ++ R GQR GS S S + + EE A A + +SS
Sbjct: 208 RSKERHREHRRRDGQRGGSEASKSRSRH-SHSGEERAEVAKSGSSS-------------- 252
Query: 325 QPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTS-----------SGHRTEKRKPQ 373
+G RR S ++S++ +DR+ +A + +S +R +K +P+
Sbjct: 253 ----SSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPK 308
Query: 374 -QPQRRPAAGTGQRRGSGSSPSADQ 397
+RR + G R S S A Q
Sbjct: 309 AYRRRRSLSPLGGRDDSPVSHRASQ 333
Score = 47.8 bits (112), Expect = 2e-05
Identities = 77/295 (26%), Positives = 113/295 (38%), Gaps = 70/295 (23%)
Query: 142 AAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAP 201
AAA+ S G E ++ + +RR G +RRG P A
Sbjct: 74 AAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRG----PRA------------------ 111
Query: 202 TSRGHRTEKRKP-QQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEE------AAAAPAP 254
G EKR+ PQ + GG G G +P + + + E+ A+AA A
Sbjct: 112 ---GQEAEKRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAA 168
Query: 255 TSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPA--PTSSGH 312
T+ AGGTG GSG SP A G Q R E + P SS
Sbjct: 169 TA-----------------AGGTG---GSGGSP-ASSSGTQRRGEGSERRPRRDRRSSSG 207
Query: 313 RTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQ--QGAQDREEEAAAAPVPTSSGHR---- 366
R+++R R + GQR GS S S ++ ++R E A + +S G R
Sbjct: 208 RSKERHR-----EHRRRDGQRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSAS 262
Query: 367 -TEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREE---EVRKWKKRVDLS 417
T + R A + + S PSA ++ + E E + +++R LS
Sbjct: 263 ATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLS 317
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 59.7 bits (143), Expect = 5e-09
Identities = 84/368 (22%), Positives = 132/368 (35%), Gaps = 73/368 (19%)
Query: 39 PQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSS 98
PQ Q GG G G G +P + + + E+ A +AA T+
Sbjct: 124 PQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGA------------SAATAATA- 170
Query: 99 GHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKR 158
AGGTG GS +S S Q+R + E R R+
Sbjct: 171 ----------------AGGTGGSGGSPASSSGTQRRGEGSERR-------PRRDRRSSSG 207
Query: 159 KRQQPQRRPAGGTGQRRGSGSSPSADQ--QGAQDREEEAAAAPAPTSRGHRTEKRKPQQP 216
+ ++ R GQR GS +S S + ++R E A + + +S G R
Sbjct: 208 RSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRR--------- 258
Query: 217 QCRPAGGTGQRRGSRSSPSADQQRAQDR-EEEAAAAPAPTSRGHRTEKRKPQQPQRR--- 272
+ A T SR + R++ + +E +A + +R +K +P+ +RR
Sbjct: 259 --KSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSL 316
Query: 273 -PAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTG 331
P GG R S S A Q + +P+P G R+ L P+ +
Sbjct: 317 SPLGG---RDDSPVSHRASQ------SLRSRKSPSPAGGGSSPYSRR---LPRSPSPYSR 364
Query: 332 QRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGS 391
+R S S+ ++G +P P SS R P P R + + R S
Sbjct: 365 RRSPSYSRHSSYERGGD-------VSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSS 417
Query: 392 SPSADQQR 399
S + R
Sbjct: 418 RHSRSRSR 425
Score = 53.5 bits (127), Expect = 3e-07
Identities = 66/265 (24%), Positives = 102/265 (38%), Gaps = 62/265 (23%)
Query: 152 GHRTEKRKR-QQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEE------AAAAPAPTSR 204
G EKR+ PQ + GG G G G +P + + + E+ A+AA A T+
Sbjct: 112 GQEAEKRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATA- 170
Query: 205 GHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKR 264
AGGTG GS +S S Q+R + E R R+
Sbjct: 171 ----------------AGGTGGSGGSPASSSGTQRRGEGSERR-------PRRDRRSSSG 207
Query: 265 KPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQC 324
+ ++ R GQR GS S S + + EE A A + +SS
Sbjct: 208 RSKERHREHRRRDGQRGGSEASKSRSRH-SHSGEERAEVAKSGSSS-------------- 252
Query: 325 QPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTS-----------SGHRTEKRKPQ 373
+G RR S ++S++ +DR+ +A + +S +R +K +P+
Sbjct: 253 ----SSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPK 308
Query: 374 -QPQRRPAAGTGQRRGSGSSPSADQ 397
+RR + G R S S A Q
Sbjct: 309 AYRRRRSLSPLGGRDDSPVSHRASQ 333
Score = 47.8 bits (112), Expect = 2e-05
Identities = 77/295 (26%), Positives = 113/295 (38%), Gaps = 70/295 (23%)
Query: 142 AAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAP 201
AAA+ S G E ++ + +RR G +RRG P A
Sbjct: 74 AAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRG----PRA------------------ 111
Query: 202 TSRGHRTEKRKP-QQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEE------AAAAPAP 254
G EKR+ PQ + GG G G +P + + + E+ A+AA A
Sbjct: 112 ---GQEAEKRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAA 168
Query: 255 TSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPA--PTSSGH 312
T+ AGGTG GSG SP A G Q R E + P SS
Sbjct: 169 TA-----------------AGGTG---GSGGSP-ASSSGTQRRGEGSERRPRRDRRSSSG 207
Query: 313 RTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQ--QGAQDREEEAAAAPVPTSSGHR---- 366
R+++R R + GQR GS S S ++ ++R E A + +S G R
Sbjct: 208 RSKERHR-----EHRRRDGQRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSAS 262
Query: 367 -TEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREE---EVRKWKKRVDLS 417
T + R A + + S PSA ++ + E E + +++R LS
Sbjct: 263 ATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLS 317
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 58.5 bits (140), Expect = 1e-08
Identities = 86/383 (22%), Positives = 138/383 (36%), Gaps = 58/383 (15%)
Query: 28 EKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG-AQDREEEAAAAPAADQQRAQDRE 86
+ + P+ + + QP GGT PS QQG + + P Q R
Sbjct: 379 QPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA 438
Query: 87 EEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAP 146
+ A G + ++ Q G GQ+ +P +QQ ++++ +
Sbjct: 439 QSA--------MGGLSYTQQIPPYGQQGPSGYGQQ---GQTPYYNQQSPHPQQQQPPYSQ 487
Query: 147 VPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGH 206
P S+ + +QQPQ +P + S P QQ +Q ++ +PAP
Sbjct: 488 QPPSQTPHAQPSYQQQPQSQPP------QLQSSQPPYSQQPSQPPHQQ---SPAPYPSQQ 538
Query: 207 RTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQD-REEEAAAAPAPTSRGHRTEKRK 265
T ++ PQ S P Q +AQ +++ PAP++ + +
Sbjct: 539 STTQQHPQ-----------------SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQ 581
Query: 266 PQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQ 325
PQ Q + + QR S D G+Q A++AP+ TSS E L LQ +
Sbjct: 582 PQSQQSQQTAYSQQRFPPPQELSQDSFGSQ-----ASSAPSMTSSKGGQED-MNLSLQSR 635
Query: 326 PAG-------------GTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKP 372
P+ GT G S+S ++ A + P +S H R P
Sbjct: 636 PSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGP 695
Query: 373 QQPQRRPAAGTGQRRGSGSSPSA 395
A Q R SP+A
Sbjct: 696 SPSPVGSPASVAQSRSGPLSPAA 718
Score = 43.1 bits (100), Expect = 5e-04
Identities = 71/272 (26%), Positives = 94/272 (34%), Gaps = 41/272 (15%)
Query: 59 ADQQGAQDREEEAAAAPAADQ---QRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQP- 114
A+QQ ++ EAAAA AA++ + A +E E A P G K LQ +
Sbjct: 27 AEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLG------KELQDGAESN 80
Query: 115 AGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQR 174
GG G GS P A+ + A P P + TE P GG
Sbjct: 81 GGGGGGGAGSGGGPGAEPDL---KNSNGNAGPRPALNNNLTE----------PPGG---- 123
Query: 175 RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSP 234
G S+D GA AAA P P + R P A Q+ G + SP
Sbjct: 124 ---GGGGSSDGVGAPP-HSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSP 179
Query: 235 S-ADQQRAQDREEEAAAAPAPTSRGHRTEK--------RKPQQPQRRPAGGTGQRRGSGY 285
A Q E A P S H + P PA RG G
Sbjct: 180 GLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG-GT 238
Query: 286 SPSADQQGAQDREEEAAAAPAPTSSGHRTEKR 317
S A + +++A A +SS ++R
Sbjct: 239 PGSGAAAAAGSKPPPSSSASASSSSSSFAQQR 270
Score = 40.4 bits (93), Expect = 0.003
Identities = 67/290 (23%), Positives = 90/290 (31%), Gaps = 29/290 (10%)
Query: 102 TEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQ 161
+E +K Q Q + AGG + + ++ + + A +E E A P G ++ Q
Sbjct: 22 SELKKAEQQQREEAGG--EAAAAAAAERGEMKAAAGQESEGPAVGPPQPLG-----KELQ 74
Query: 162 QPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPA 221
GG G GSG P A+ + A P P + TE P
Sbjct: 75 DGAESNGGGGGGGAGSGGGPGAE---PDLKNSNGNAGPRPALNNNLTEP---------PG 122
Query: 222 GGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRR 281
GG G GS A A AAA P P + R P A Q+
Sbjct: 123 GGGG---GSSDGVGAPPHSA------AAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQH 173
Query: 282 GSGYSPS-ADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSS 340
G SP A Q E A P S H + + SS
Sbjct: 174 GGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSS 233
Query: 341 SANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSG 390
A + P P+SS + QR A G G +G
Sbjct: 234 PRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAG 283
Score = 38.9 bits (89), Expect = 0.009
Identities = 57/257 (22%), Positives = 88/257 (34%), Gaps = 35/257 (13%)
Query: 155 TEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQ 214
+E +K +Q QR AG G+ + ++ + + A +E E A P G ++ Q
Sbjct: 22 SELKKAEQQQREEAG--GEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLG-----KELQ 74
Query: 215 QPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPA 274
GG G GS P A+ + A P P + TE
Sbjct: 75 DGAESNGGGGGGGAGSGGGPGAEPDL---KNSNGNAGPRPALNNNLTEP--------PGG 123
Query: 275 GGTGQRRGSGYSPSA------------DQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQL 322
GG G G G P + Q + AAAA A H ++ L
Sbjct: 124 GGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGL-A 182
Query: 323 QCQPAGGTGQRRGSGCSSSANQQGAQDREEEA----AAAPVPTSSGHRTEKRKPQQPQRR 378
Q GG G +G +++ G + + + +A P + + + P
Sbjct: 183 ALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSG 242
Query: 379 PAAGTGQRRGSGSSPSA 395
AA G + SS SA
Sbjct: 243 AAAAAGSKPPPSSSASA 259
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 58.5 bits (140), Expect = 1e-08
Identities = 86/383 (22%), Positives = 138/383 (36%), Gaps = 58/383 (15%)
Query: 28 EKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG-AQDREEEAAAAPAADQQRAQDRE 86
+ + P+ + + QP GGT PS QQG + + P Q R
Sbjct: 379 QPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA 438
Query: 87 EEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAP 146
+ A G + ++ Q G GQ+ +P +QQ ++++ +
Sbjct: 439 QSA--------MGGLSYTQQIPPYGQQGPSGYGQQ---GQTPYYNQQSPHPQQQQPPYSQ 487
Query: 147 VPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGH 206
P S+ + +QQPQ +P + S P QQ +Q ++ +PAP
Sbjct: 488 QPPSQTPHAQPSYQQQPQSQPP------QLQSSQPPYSQQPSQPPHQQ---SPAPYPSQQ 538
Query: 207 RTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQD-REEEAAAAPAPTSRGHRTEKRK 265
T ++ PQ S P Q +AQ +++ PAP++ + +
Sbjct: 539 STTQQHPQ-----------------SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQ 581
Query: 266 PQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQ 325
PQ Q + + QR S D G+Q A++AP+ TSS E L LQ +
Sbjct: 582 PQSQQSQQTAYSQQRFPPPQELSQDSFGSQ-----ASSAPSMTSSKGGQED-MNLSLQSR 635
Query: 326 PAG-------------GTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKP 372
P+ GT G S+S ++ A + P +S H R P
Sbjct: 636 PSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGP 695
Query: 373 QQPQRRPAAGTGQRRGSGSSPSA 395
A Q R SP+A
Sbjct: 696 SPSPVGSPASVAQSRSGPLSPAA 718
Score = 43.1 bits (100), Expect = 5e-04
Identities = 71/272 (26%), Positives = 94/272 (34%), Gaps = 41/272 (15%)
Query: 59 ADQQGAQDREEEAAAAPAADQ---QRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQP- 114
A+QQ ++ EAAAA AA++ + A +E E A P G K LQ +
Sbjct: 27 AEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLG------KELQDGAESN 80
Query: 115 AGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQR 174
GG G GS P A+ + A P P + TE P GG
Sbjct: 81 GGGGGGGAGSGGGPGAEPDL---KNSNGNAGPRPALNNNLTE----------PPGG---- 123
Query: 175 RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSP 234
G S+D GA AAA P P + R P A Q+ G + SP
Sbjct: 124 ---GGGGSSDGVGAPP-HSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSP 179
Query: 235 S-ADQQRAQDREEEAAAAPAPTSRGHRTEK--------RKPQQPQRRPAGGTGQRRGSGY 285
A Q E A P S H + P PA RG G
Sbjct: 180 GLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG-GT 238
Query: 286 SPSADQQGAQDREEEAAAAPAPTSSGHRTEKR 317
S A + +++A A +SS ++R
Sbjct: 239 PGSGAAAAAGSKPPPSSSASASSSSSSFAQQR 270
Score = 40.4 bits (93), Expect = 0.003
Identities = 67/290 (23%), Positives = 90/290 (31%), Gaps = 29/290 (10%)
Query: 102 TEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQ 161
+E +K Q Q + AGG + + ++ + + A +E E A P G ++ Q
Sbjct: 22 SELKKAEQQQREEAGG--EAAAAAAAERGEMKAAAGQESEGPAVGPPQPLG-----KELQ 74
Query: 162 QPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPA 221
GG G GSG P A+ + A P P + TE P
Sbjct: 75 DGAESNGGGGGGGAGSGGGPGAE---PDLKNSNGNAGPRPALNNNLTEP---------PG 122
Query: 222 GGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRR 281
GG G GS A A AAA P P + R P A Q+
Sbjct: 123 GGGG---GSSDGVGAPPHSA------AAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQH 173
Query: 282 GSGYSPS-ADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSS 340
G SP A Q E A P S H + + SS
Sbjct: 174 GGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSS 233
Query: 341 SANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSG 390
A + P P+SS + QR A G G +G
Sbjct: 234 PRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAG 283
Score = 38.9 bits (89), Expect = 0.009
Identities = 57/257 (22%), Positives = 88/257 (34%), Gaps = 35/257 (13%)
Query: 155 TEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQ 214
+E +K +Q QR AG G+ + ++ + + A +E E A P G ++ Q
Sbjct: 22 SELKKAEQQQREEAG--GEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLG-----KELQ 74
Query: 215 QPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPA 274
GG G GS P A+ + A P P + TE
Sbjct: 75 DGAESNGGGGGGGAGSGGGPGAEPDL---KNSNGNAGPRPALNNNLTEP--------PGG 123
Query: 275 GGTGQRRGSGYSPSA------------DQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQL 322
GG G G G P + Q + AAAA A H ++ L
Sbjct: 124 GGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGL-A 182
Query: 323 QCQPAGGTGQRRGSGCSSSANQQGAQDREEEA----AAAPVPTSSGHRTEKRKPQQPQRR 378
Q GG G +G +++ G + + + +A P + + + P
Sbjct: 183 ALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSG 242
Query: 379 PAAGTGQRRGSGSSPSA 395
AA G + SS SA
Sbjct: 243 AAAAAGSKPPPSSSASA 259
>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
Length = 2303
Score = 58.5 bits (140), Expect = 1e-08
Identities = 89/384 (23%), Positives = 132/384 (34%), Gaps = 63/384 (16%)
Query: 36 QQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPV- 94
Q P+ QP G G++R +G P++ +Q R + A +A+Q R + P+
Sbjct: 1412 QGPPRDQPGGPAGRQRPTGR-PTSARQAMGHRHKAGGAGRSAEQSRGAGKNRAGLELPLG 1470
Query: 95 -PTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRA---------------QDR 138
P S+ PA G + G A Q
Sbjct: 1471 RPPSA---------------PADKDGSKPGRTRGDGALQSLCLTTPTEEAVYCFYGNDSD 1515
Query: 139 EEEAAAAPVPTSRGHRTEKR--KRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAA 196
EE AAAP PT R R R++PQ R + + P A Q + +E
Sbjct: 1516 EEPPAAAPTPTHRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAPPPARTQPSLIADETPP 1575
Query: 197 AAPAPTSRGHRTEKRKPQQPQCRPAG---------GTGQRRGSRSSPSADQQRAQDREEE 247
+S +E + P P G G G R S SP A ++ Q
Sbjct: 1576 CYSLSSSASSLSEPEPSEPPAVHPRGREPAVTKDPGPGGGRDSSPSPRAAEELLQRCISS 1635
Query: 248 AAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQR--RGSGYSPSAD---------QQGAQD 296
A P G R K + + RPA G+ +R +G ++D Q+GA
Sbjct: 1636 ALPRRRPPVSGLRRRKPRATRLDERPAEGSRERGEEAAGSDRASDLDSVEWRAIQEGANS 1695
Query: 297 REEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQ----RRGSGCSSSANQQGAQDREE 352
A A T + G T Q R+G + + G+ R E
Sbjct: 1696 IVTWLHQAAAATREASSESDSILSFVSGLSVGSTLQPPKHRKG---RQAEGEMGSARRPE 1752
Query: 353 EAAAAPVPTSSGHRTEKRKPQQPQ 376
+ AA V TS R+ P++P+
Sbjct: 1753 KRGAASVKTSGSPRS-PAGPEKPR 1775
Score = 54.7 bits (130), Expect = 2e-07
Identities = 97/399 (24%), Positives = 134/399 (33%), Gaps = 72/399 (18%)
Query: 44 AGGTG------QRRGSGSSPSADQ-QGAQDREEE------AAAAPAADQQRAQDREEEAA 90
AGG G +RR G +P+ + +GA D+E E AA PA R + A
Sbjct: 1308 AGGAGLHFAGHRRREEGPAPTGSRPRGAADQELELLRECLGAAVPA--------RLRKVA 1359
Query: 91 AAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTS 150
+A VP G R L PA P+ + D E PV S
Sbjct: 1360 SALVP---GRRALPVPVYMLVPAPA------------PAQEDDSCTDSAE---GTPVNFS 1401
Query: 151 RGHRTEKRKRQQPQR-RPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTE 209
Q P R +P G G++R +G SA Q + A A SRG
Sbjct: 1402 SAASLSDETLQGPPRDQPGGPAGRQRPTGRPTSARQAMGHRHKAGGAGRSAEQSRGAGKN 1461
Query: 210 KRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQ-------------------DREEEAAA 250
+ + P RP + GS+ + Q EE AA
Sbjct: 1462 RAGLELPLGRPPSAPADKDGSKPGRTRGDGALQSLCLTTPTEEAVYCFYGNDSDEEPPAA 1521
Query: 251 APAPTSRGHRTEKR--KPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPT 308
AP PT R R ++PQ R + P A Q + +E +
Sbjct: 1522 APTPTHRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAPPPARTQPSLIADETPPCYSLSS 1581
Query: 309 SSGHRTEKRKRLQLQCQPAG---------GTGQRRGSGCSSSANQQGAQDREEEAAAAPV 359
S+ +E P G G G R S S A ++ Q A
Sbjct: 1582 SASSLSEPEPSEPPAVHPRGREPAVTKDPGPGGGRDSSPSPRAAEELLQRCISSALPRRR 1641
Query: 360 PTSSGHRTEKRKPQQPQRRPAAGTGQR--RGSGSSPSAD 396
P SG R K + + RPA G+ +R +GS ++D
Sbjct: 1642 PPVSGLRRRKPRATRLDERPAEGSRERGEEAAGSDRASD 1680
>gi|221316599 chromogranin B precursor [Homo sapiens]
Length = 677
Score = 57.4 bits (137), Expect = 2e-08
Identities = 86/399 (21%), Positives = 141/399 (35%), Gaps = 56/399 (14%)
Query: 16 RESSEGDQWL---------ENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQD 66
RE ++ QW E KT+ Q+ + G ++G S++++ ++
Sbjct: 131 RERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEE 190
Query: 67 REEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRS 126
E A +Q + ++EE A ++GH EK + Q +G + +
Sbjct: 191 PGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHP 250
Query: 127 SPSADQQRAQDREEEA---AAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSA 183
S Q R+Q+ EE A + V R R +P R G GS PS
Sbjct: 251 QESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQG--------GSLPSE 302
Query: 184 DQQGAQDREEEA--AAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRA 241
++ Q+ EE+ + A R H + + + + G ++ + +R
Sbjct: 303 EKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERY 362
Query: 242 QDREEEAAAAPAPTSRGHRTEKRKPQQPQ---RRPAGGTGQ---------------RRGS 283
+ R E AP P S E+ K P + A G G+ RG
Sbjct: 363 RGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGR 422
Query: 284 GYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGS------- 336
G P A + REE+ HR ++ + + + P G + +
Sbjct: 423 GGEPRAYFM-SDTREEKRFLG----EGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEE 477
Query: 337 GCSSSANQQG----AQDREEEAAAAPVPTSSGHRTEKRK 371
G QQG ++ EEA SS H EKRK
Sbjct: 478 GAPGKWQQQGDLQDTKENREEARFQDKQYSSHHTAEKRK 516
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 57.0 bits (136), Expect = 3e-08
Identities = 81/409 (19%), Positives = 155/409 (37%), Gaps = 53/409 (12%)
Query: 10 TRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREE 69
TR L + Q + K K + P+ + + S S + +++R+
Sbjct: 318 TRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDH 377
Query: 70 EAAAAPAADQQRAQ----DREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSR 125
+++P + R+Q +++ + + + P + R+ R + + + + +
Sbjct: 378 RGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDR-SRSRSPNKARD 436
Query: 126 SSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQ 185
S S +A+DR SR K + R P + R SPS
Sbjct: 437 CSRSRSPYKARDR-----------SRSRSPNKARDHSRSRSP--NKARDRSRSRSPS--- 480
Query: 186 QGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSR--SSPSADQQRAQD 243
++R+ +P+ R HR + ++ QCR + + + R R SPS ++QR Q
Sbjct: 481 ---KERDHSQLGSPSK-ERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQS 536
Query: 244 REEEAAAAPAPTSRGHRTEKRKPQQPQ-----RRPAGGTGQRRGSGYSPSADQQGAQDR- 297
R +P R++ R P + + R P+ +RR SPS +++ Q R
Sbjct: 537 R--------SPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWR--SPSKERERRQSRS 586
Query: 298 ---EEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEA 354
E + + + +P + R + + T + G + +Q +E +
Sbjct: 587 SSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEG-----NHSQSRTSSKESDP 641
Query: 355 AAAPVPTS-SGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQD 402
+ + VP S R+ R Q R + T S + PS Q +QD
Sbjct: 642 SQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPS-TFPSGGQTLSQD 689
Score = 47.4 bits (111), Expect = 2e-05
Identities = 80/430 (18%), Positives = 146/430 (33%), Gaps = 57/430 (13%)
Query: 2 KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQ 61
+ R Q L K G + + P P G + + SPS+ +
Sbjct: 181 RERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSR 240
Query: 62 QGAQDRE-----EEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAG 116
+ + E + +P R + + + + + S R+ +R R
Sbjct: 241 KVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSR--------S 292
Query: 117 GTGQRRGSR---SSPSADQQRAQDREEEAAAAPV---PTSRGHRTEKRKRQQ--PQRRPA 168
G+ +R SR S + RA+ R + + + SR H K + Q P+R +
Sbjct: 293 GSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRS 352
Query: 169 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRR 228
+ S S + +++R+ +++P S ++ Q+ R R
Sbjct: 353 HNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARD 412
Query: 229 GSRS-SPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSP 287
SRS SP + R++ R A SR K + + R P R +
Sbjct: 413 RSRSRSPYKARDRSRSRSPNKAR---DCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNK 469
Query: 288 SADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGA 347
+ D+ ++ +E + + S R +R R S S +Q
Sbjct: 470 ARDRSRSRSPSKERDHSQLGSPSKERDHRRSR-------------------SPSKERQCR 510
Query: 348 QDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQR--RGSGSSPSAD----QQRAQ 401
Q R HR + ++ QRR + + R SPS + Q R+
Sbjct: 511 QSRSSSK-------ERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSP 563
Query: 402 DREEEVRKWK 411
+E + R+W+
Sbjct: 564 SKERDRRRWR 573
Score = 41.6 bits (96), Expect = 0.001
Identities = 42/212 (19%), Positives = 85/212 (40%), Gaps = 21/212 (9%)
Query: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG 63
R+ ++ R+ R+S + ++ +++ ++Q + + + R SPS +++
Sbjct: 498 RRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREH 557
Query: 64 AQ------DREEEAAAAPAADQQRAQDR----EEEAAAAPVPTSSGHRTEKRKRLQLQCQ 113
Q +R+ +P+ +++R Q R E + + + P + R + +
Sbjct: 558 RQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAH 617
Query: 114 PAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRG-HRTEKRKRQQPQRRPAGGTG 172
T + G+ S Q R +E + + + VP S R+ R Q R T
Sbjct: 618 SRSRTPSKEGNHS-----QSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKT- 671
Query: 173 QRRGSGSSPSADQQGAQDREEEAAAAPAPTSR 204
S SPS G Q ++ + A A TS+
Sbjct: 672 ----SSHSPSTFPSGGQTLSQDDSQADATTSK 699
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 56.6 bits (135), Expect = 4e-08
Identities = 95/437 (21%), Positives = 154/437 (35%), Gaps = 72/437 (16%)
Query: 36 QQQPQCQPAGGTGQRRG-----------SGSSPSADQQGAQDREEEAAAAPAADQQRAQD 84
Q +P PA G Q+ G +S S+++ EEA AA A Q +
Sbjct: 500 QAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL 559
Query: 85 REEEAAAAPVPTSSGHR---------TEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRA 135
+ + A P T++ T+ ++ PAG + G P+ D +
Sbjct: 560 KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSS 619
Query: 136 Q--DREEEAAAAPVPT----SRGHRTEKRKRQQPQRRPAG-GTGQRRGSGSSPSADQQGA 188
+ D EEE V S G + + P + G GT + P+ Q A
Sbjct: 620 EESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKA 679
Query: 189 QDRE-----------EEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSAD 237
+ +E EEAAA+PA +T +K Q A +G+ S+P
Sbjct: 680 EKQEDSESSEEESDSEEAAASPAQV----KTSVKKTQAKANPAAARAPSAKGTISAPGKV 735
Query: 238 QQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGG----------TGQRRGSGYSP 287
A ++ + + P R + + P P+ G TG SG
Sbjct: 736 VTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSG--- 792
Query: 288 SADQQGAQDREEEAAAAPAPTSSGHR-------TEKRKRLQLQCQPAGGTG----QRRGS 336
S++++ + E E A P+ H+ ++ R P G TG Q
Sbjct: 793 SSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQ 852
Query: 337 GCSSSANQQGAQDREEEAA---AAPVPTSSGHRTEKRKPQQPQRRPA---AGTGQRRGSG 390
S S++++ D E AA A + R P P PA A + R+
Sbjct: 853 DDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARA 912
Query: 391 SSPSADQQRAQDREEEV 407
S +A ++ +E+V
Sbjct: 913 SESTARSSSSESEDEDV 929
Score = 45.1 bits (105), Expect = 1e-04
Identities = 91/453 (20%), Positives = 144/453 (31%), Gaps = 85/453 (18%)
Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPV 94
P++ P G TG + ++ EE + A Q + + + AA
Sbjct: 305 PRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASA 364
Query: 95 PTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHR 154
P R + PA Q G + S D + EA AA
Sbjct: 365 PAKESPRKGAAPAPPRKTGPAAAQVQV-GKQEEDSRSSSEESDSDREALAA-----MNAA 418
Query: 155 TEKRKRQQPQRRPAGGTGQ---RRGSG---------SSPSA-------DQQGAQDREEEA 195
K + PQ +PA G +G+G ++PSA D + + + ++
Sbjct: 419 QVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDS 478
Query: 196 AAAPAPTSRGHRTEKR----KPQQPQCRPAGGTGQRRG------------------SRSS 233
+ PT+ EK +P PA G Q+ G SS
Sbjct: 479 SDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESS 538
Query: 234 PSADQQRAQDREEEAAAAPA---PTSRG-----HRTEKRK-------PQQPQR-----RP 273
SAD + A A A PA P ++ + T K Q P++ P
Sbjct: 539 DSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSP 598
Query: 274 AGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPA---GGT 330
AG + G P+ D +++ + E + G K LQ++ G
Sbjct: 599 AGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSL 658
Query: 331 GQRRG----SGCSSSANQQGAQDRE-----------EEAAAAPVPTSSGHRTEKRKPQQP 375
GQ + Q A+ +E EEAAA+P + + + K
Sbjct: 659 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 718
Query: 376 QRRPAAGTGQRRGSGSSPSADQQRAQDREEEVR 408
R + G G +A Q Q +V+
Sbjct: 719 AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 751
Score = 39.3 bits (90), Expect = 0.007
Identities = 58/311 (18%), Positives = 117/311 (37%), Gaps = 29/311 (9%)
Query: 124 SRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSA 183
SR+ ++ A+ E++ A G+ T Q A S SS A
Sbjct: 1101 SRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLA 1160
Query: 184 ---DQQGAQD-REEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQ 239
D G Q+ + ++AA +P + G Q +P G G + S + ++
Sbjct: 1161 AKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNIT 1220
Query: 240 RA--------QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGG--TGQRRGSGYSPSA 289
+ + + +A+ T + K+ + G + +R+ SG P+A
Sbjct: 1221 QCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAA 1280
Query: 290 DQQGAQDREE-------EAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSA 342
++ +++ EA+ +P TS+ + + ++ + +G +++G G S
Sbjct: 1281 RTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRD-----KASGDVKEKKGKG---SL 1332
Query: 343 NQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQD 402
QGA+D EE + T G K ++ +++ + A + +D
Sbjct: 1333 GSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKD 1392
Query: 403 REEEVRKWKKR 413
E +K KK+
Sbjct: 1393 SESPSQKKKKK 1403
Score = 38.5 bits (88), Expect = 0.011
Identities = 76/403 (18%), Positives = 144/403 (35%), Gaps = 70/403 (17%)
Query: 27 NEKTKPLRPQ-QQPQCQPAGGTGQRRGSGSSPSADQ-----QGAQDREEEAAAAPA---- 76
N+ KP P+ QQ P S SS +++ QGA+ P+
Sbjct: 1046 NKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTET 1105
Query: 77 -ADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRA 135
++ A+ E++ A SG+ T Q A S SS A +
Sbjct: 1106 LVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDP 1165
Query: 136 QDREE----EAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSAD------- 184
++E +AA P + G Q R+P G G + S + ++
Sbjct: 1166 DGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLG 1225
Query: 185 QQGAQDREEEAAAAPAPTSRGHRTEKRK---PQQPQCRPAGGTGQRRGSRSSPSADQQRA 241
Q + + A+ + E++K + R + +R+ S P+A R+
Sbjct: 1226 QPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRS 1285
Query: 242 QDREE-------EAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGA 294
+ +++ EA+ +P TS T K K ++ + +G +++G G S QGA
Sbjct: 1286 KKKKKLGAGEGGEASVSPEKTST---TSKGKAKRD--KASGDVKEKKGKG---SLGSQGA 1337
Query: 295 QDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEA 354
+D EE +LQ +G G +Q + ++E+
Sbjct: 1338 KDEPEE--------------------ELQ----------KGMGTVEGGDQSNPKSKKEKK 1367
Query: 355 AAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQ 397
+ + +K+K ++ + + Q++ +A+Q
Sbjct: 1368 KSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1410
Score = 35.4 bits (80), Expect = 0.097
Identities = 28/135 (20%), Positives = 57/135 (42%), Gaps = 12/135 (8%)
Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
PR K++ +KL G+ + EKT + + + +G +++G GS S Q
Sbjct: 1283 PRSKKK----KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS---Q 1335
Query: 63 GAQDREEEA-----AAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGG 117
GA+D EE DQ + ++E+ + + +K+K + + +
Sbjct: 1336 GAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSES 1395
Query: 118 TGQRRGSRSSPSADQ 132
Q++ + +A+Q
Sbjct: 1396 PSQKKKKKKKKTAEQ 1410
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 56.6 bits (135), Expect = 4e-08
Identities = 95/437 (21%), Positives = 154/437 (35%), Gaps = 72/437 (16%)
Query: 36 QQQPQCQPAGGTGQRRGS-----------GSSPSADQQGAQDREEEAAAAPAADQQRAQD 84
Q +P PA G Q+ G +S S+++ EEA AA A Q +
Sbjct: 577 QAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL 636
Query: 85 REEEAAAAPVPTSSGHR---------TEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRA 135
+ + A P T++ T+ ++ PAG + G P+ D +
Sbjct: 637 KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSS 696
Query: 136 Q--DREEEAAAAPVPT----SRGHRTEKRKRQQPQRRPAG-GTGQRRGSGSSPSADQQGA 188
+ D EEE V S G + + P + G GT + P+ Q A
Sbjct: 697 EESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKA 756
Query: 189 QDRE-----------EEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSAD 237
+ +E EEAAA+PA +T +K Q A +G+ S+P
Sbjct: 757 EKQEDSESSEEESDSEEAAASPAQV----KTSVKKTQAKANPAAARAPSAKGTISAPGKV 812
Query: 238 QQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGG----------TGQRRGSGYSP 287
A ++ + + P R + + P P+ G TG SG
Sbjct: 813 VTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSG--- 869
Query: 288 SADQQGAQDREEEAAAAPAPTSSGHR-------TEKRKRLQLQCQPAGGTG----QRRGS 336
S++++ + E E A P+ H+ ++ R P G TG Q
Sbjct: 870 SSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQ 929
Query: 337 GCSSSANQQGAQDREEEAA---AAPVPTSSGHRTEKRKPQQPQRRPA---AGTGQRRGSG 390
S S++++ D E AA A + R P P PA A + R+
Sbjct: 930 DDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARA 989
Query: 391 SSPSADQQRAQDREEEV 407
S +A ++ +E+V
Sbjct: 990 SESTARSSSSESEDEDV 1006
Score = 55.8 bits (133), Expect = 7e-08
Identities = 79/392 (20%), Positives = 135/392 (34%), Gaps = 51/392 (13%)
Query: 46 GTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKR 105
GT + P+ Q A+ +E+ ++ +D EEAAA+P +
Sbjct: 738 GTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDS-------EEAAASPAQVKTSV----- 785
Query: 106 KRLQLQCQPAGGTG-QRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQ 164
K+ Q + PA +G+ S+P A ++ + + P R + + P
Sbjct: 786 KKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPA 845
Query: 165 RRPAGG----------TGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQ 214
P+ G TG SGSS +++ + E E A P+ + H+
Sbjct: 846 SVPSVGKAVATAAQAQTGPEEDSGSS---EEESDSEEEAETLAQVKPSGKTHQIRAALAP 902
Query: 215 QPQCRPAGGTGQRRGSRSSPSADQQRAQD-----REEEAAAAPAPTSRGHRTEKRKPQ-- 267
+ P G ++ PSA Q QD EE + AP + + P
Sbjct: 903 AKES-PRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIF 961
Query: 268 -QPQRRPAG----------GTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTE- 315
P R PAG + R+ +A ++ +E+ A + G RT
Sbjct: 962 VDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNV 1021
Query: 316 -----KRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKR 370
R+ + AG + + S S Q+G + + A TS + +
Sbjct: 1022 VTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQA 1081
Query: 371 KPQQPQRRPAAGTGQRRGSGSSPSADQQRAQD 402
K R+P Q+ S D + + D
Sbjct: 1082 KGTNKLRKPKLPEVQQATKAPESSDDSEDSSD 1113
Score = 45.1 bits (105), Expect = 1e-04
Identities = 91/453 (20%), Positives = 144/453 (31%), Gaps = 85/453 (18%)
Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPV 94
P++ P G TG + ++ EE + A Q + + + AA
Sbjct: 382 PRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASA 441
Query: 95 PTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHR 154
P R + PA Q G + S D + EA AA
Sbjct: 442 PAKESPRKGAAPAPPRKTGPAAAQVQV-GKQEEDSRSSSEESDSDREALAA-----MNAA 495
Query: 155 TEKRKRQQPQRRPAGGTGQ---RRGSG---------SSPSA-------DQQGAQDREEEA 195
K + PQ +PA G +G+G ++PSA D + + + ++
Sbjct: 496 QVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDS 555
Query: 196 AAAPAPTSRGHRTEKR----KPQQPQCRPAGGTGQRRG------------------SRSS 233
+ PT+ EK +P PA G Q+ G SS
Sbjct: 556 SDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESS 615
Query: 234 PSADQQRAQDREEEAAAAPA---PTSRG-----HRTEKRK-------PQQPQR-----RP 273
SAD + A A A PA P ++ + T K Q P++ P
Sbjct: 616 DSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSP 675
Query: 274 AGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPA---GGT 330
AG + G P+ D +++ + E + G K LQ++ G
Sbjct: 676 AGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSL 735
Query: 331 GQRRG----SGCSSSANQQGAQDRE-----------EEAAAAPVPTSSGHRTEKRKPQQP 375
GQ + Q A+ +E EEAAA+P + + + K
Sbjct: 736 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 795
Query: 376 QRRPAAGTGQRRGSGSSPSADQQRAQDREEEVR 408
R + G G +A Q Q +V+
Sbjct: 796 AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828
Score = 40.0 bits (92), Expect = 0.004
Identities = 77/422 (18%), Positives = 146/422 (34%), Gaps = 51/422 (12%)
Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAA-PAADQQ------------R 81
P+ P+ AG + + S S Q+G + + A PA Q R
Sbjct: 1029 PRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLR 1088
Query: 82 AQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRG---------SRSSPSADQ 132
E A P SS + + G + SR+ ++
Sbjct: 1089 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEE 1148
Query: 133 QRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSA---DQQGAQ 189
A+ E++ A G+ T Q A S SS A D G Q
Sbjct: 1149 TAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQ 1208
Query: 190 D-REEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRA------- 241
+ + ++AA +P + G Q +P G G + S + ++ +
Sbjct: 1209 EAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWP 1268
Query: 242 -QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGG--TGQRRGSGYSPSADQQGAQDRE 298
+ + +A+ T + K+ + G + +R+ SG P+A ++ ++
Sbjct: 1269 LNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKK 1328
Query: 299 E-------EAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDRE 351
+ EA+ +P TS+ + + ++ + +G +++G G S QGA+D
Sbjct: 1329 KLGAGEGGEASVSPEKTSTTSKGKAKRD-----KASGDVKEKKGKG---SLGSQGAKDEP 1380
Query: 352 EEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEEVRKWK 411
EE + T G K ++ +++ + A + +D E +K K
Sbjct: 1381 EEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKK 1440
Query: 412 KR 413
K+
Sbjct: 1441 KK 1442
Score = 38.5 bits (88), Expect = 0.011
Identities = 76/403 (18%), Positives = 144/403 (35%), Gaps = 70/403 (17%)
Query: 27 NEKTKPLRPQ-QQPQCQPAGGTGQRRGSGSSPSADQ-----QGAQDREEEAAAAPA---- 76
N+ KP P+ QQ P S SS +++ QGA+ P+
Sbjct: 1085 NKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTET 1144
Query: 77 -ADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRA 135
++ A+ E++ A SG+ T Q A S SS A +
Sbjct: 1145 LVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDP 1204
Query: 136 QDREE----EAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSAD------- 184
++E +AA P + G Q R+P G G + S + ++
Sbjct: 1205 DGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLG 1264
Query: 185 QQGAQDREEEAAAAPAPTSRGHRTEKRK---PQQPQCRPAGGTGQRRGSRSSPSADQQRA 241
Q + + A+ + E++K + R + +R+ S P+A R+
Sbjct: 1265 QPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRS 1324
Query: 242 QDREE-------EAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGA 294
+ +++ EA+ +P TS T K K ++ + +G +++G G S QGA
Sbjct: 1325 KKKKKLGAGEGGEASVSPEKTST---TSKGKAKRD--KASGDVKEKKGKG---SLGSQGA 1376
Query: 295 QDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEA 354
+D EE +LQ +G G +Q + ++E+
Sbjct: 1377 KDEPEE--------------------ELQ----------KGMGTVEGGDQSNPKSKKEKK 1406
Query: 355 AAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQ 397
+ + +K+K ++ + + Q++ +A+Q
Sbjct: 1407 KSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1449
Score = 35.4 bits (80), Expect = 0.097
Identities = 28/135 (20%), Positives = 57/135 (42%), Gaps = 12/135 (8%)
Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
PR K++ +KL G+ + EKT + + + +G +++G GS S Q
Sbjct: 1322 PRSKKK----KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS---Q 1374
Query: 63 GAQDREEEA-----AAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGG 117
GA+D EE DQ + ++E+ + + +K+K + + +
Sbjct: 1375 GAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSES 1434
Query: 118 TGQRRGSRSSPSADQ 132
Q++ + +A+Q
Sbjct: 1435 PSQKKKKKKKKTAEQ 1449
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 56.6 bits (135), Expect = 4e-08
Identities = 95/437 (21%), Positives = 154/437 (35%), Gaps = 72/437 (16%)
Query: 36 QQQPQCQPAGGTGQRRG-----------SGSSPSADQQGAQDREEEAAAAPAADQQRAQD 84
Q +P PA G Q+ G +S S+++ EEA AA A Q +
Sbjct: 577 QAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL 636
Query: 85 REEEAAAAPVPTSSGHR---------TEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRA 135
+ + A P T++ T+ ++ PAG + G P+ D +
Sbjct: 637 KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSS 696
Query: 136 Q--DREEEAAAAPVPT----SRGHRTEKRKRQQPQRRPAG-GTGQRRGSGSSPSADQQGA 188
+ D EEE V S G + + P + G GT + P+ Q A
Sbjct: 697 EESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKA 756
Query: 189 QDRE-----------EEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSAD 237
+ +E EEAAA+PA +T +K Q A +G+ S+P
Sbjct: 757 EKQEDSESSEEESDSEEAAASPAQV----KTSVKKTQAKANPAAARAPSAKGTISAPGKV 812
Query: 238 QQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGG----------TGQRRGSGYSP 287
A ++ + + P R + + P P+ G TG SG
Sbjct: 813 VTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSG--- 869
Query: 288 SADQQGAQDREEEAAAAPAPTSSGHR-------TEKRKRLQLQCQPAGGTG----QRRGS 336
S++++ + E E A P+ H+ ++ R P G TG Q
Sbjct: 870 SSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQ 929
Query: 337 GCSSSANQQGAQDREEEAA---AAPVPTSSGHRTEKRKPQQPQRRPA---AGTGQRRGSG 390
S S++++ D E AA A + R P P PA A + R+
Sbjct: 930 DDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARA 989
Query: 391 SSPSADQQRAQDREEEV 407
S +A ++ +E+V
Sbjct: 990 SESTARSSSSESEDEDV 1006
Score = 45.1 bits (105), Expect = 1e-04
Identities = 91/453 (20%), Positives = 144/453 (31%), Gaps = 85/453 (18%)
Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPV 94
P++ P G TG + ++ EE + A Q + + + AA
Sbjct: 382 PRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASA 441
Query: 95 PTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHR 154
P R + PA Q G + S D + EA AA
Sbjct: 442 PAKESPRKGAAPAPPRKTGPAAAQVQV-GKQEEDSRSSSEESDSDREALAA-----MNAA 495
Query: 155 TEKRKRQQPQRRPAGGTGQ---RRGSG---------SSPSA-------DQQGAQDREEEA 195
K + PQ +PA G +G+G ++PSA D + + + ++
Sbjct: 496 QVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDS 555
Query: 196 AAAPAPTSRGHRTEKR----KPQQPQCRPAGGTGQRRG------------------SRSS 233
+ PT+ EK +P PA G Q+ G SS
Sbjct: 556 SDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESS 615
Query: 234 PSADQQRAQDREEEAAAAPA---PTSRG-----HRTEKRK-------PQQPQR-----RP 273
SAD + A A A PA P ++ + T K Q P++ P
Sbjct: 616 DSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSP 675
Query: 274 AGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPA---GGT 330
AG + G P+ D +++ + E + G K LQ++ G
Sbjct: 676 AGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSL 735
Query: 331 GQRRG----SGCSSSANQQGAQDRE-----------EEAAAAPVPTSSGHRTEKRKPQQP 375
GQ + Q A+ +E EEAAA+P + + + K
Sbjct: 736 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 795
Query: 376 QRRPAAGTGQRRGSGSSPSADQQRAQDREEEVR 408
R + G G +A Q Q +V+
Sbjct: 796 AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828
Score = 39.7 bits (91), Expect = 0.005
Identities = 69/393 (17%), Positives = 140/393 (35%), Gaps = 29/393 (7%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHR 101
QP+ G G+ + S Q + P + + + E++ +S
Sbjct: 1095 QPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSS 1154
Query: 102 TEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQ 161
+ Q + T SR+ ++ A+ E++ A G+ T
Sbjct: 1155 GSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA 1214
Query: 162 QPQRRPAGGTGQRRGSGSSPSA---DQQGAQD-REEEAAAAPAPTSRGHRTEKRKPQQPQ 217
Q A S SS A D G Q+ + ++AA +P + G Q
Sbjct: 1215 NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKS 1274
Query: 218 CRPAGGTGQRRGSRSSPSADQQRA--------QDREEEAAAAPAPTSRGHRTEKRKPQQP 269
+P G G + S + ++ + + + +A+ T + K+
Sbjct: 1275 RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTT 1334
Query: 270 QRRPAGG--TGQRRGSGYSPSADQQGAQDREE-------EAAAAPAPTSSGHRTEKRKRL 320
+ G + +R+ SG P+A ++ +++ EA+ +P TS+ + + ++
Sbjct: 1335 KESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRD- 1393
Query: 321 QLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPA 380
+ +G +++G G S QGA+D EE + T G K ++ +++
Sbjct: 1394 ----KASGDVKEKKGKG---SLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSD 1446
Query: 381 AGTGQRRGSGSSPSADQQRAQDREEEVRKWKKR 413
+ A + +D E +K KK+
Sbjct: 1447 KRKKDKEKKEKKKKAKKASTKDSESPSQKKKKK 1479
Score = 37.7 bits (86), Expect = 0.019
Identities = 76/424 (17%), Positives = 150/424 (35%), Gaps = 73/424 (17%)
Query: 9 DTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDRE 68
D+ + L +S ++ + T LR + P+ Q A + S G+++
Sbjct: 1101 DSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDG 1160
Query: 69 EEAAAAPAA--------------DQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQP 114
E A +A ++ A+ E++ A SG+ T Q
Sbjct: 1161 EGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1220
Query: 115 AGGTGQRRGSRSSPSADQQRAQDREE----EAAAAPVPTSRGHRTEKRKRQQPQRRPAGG 170
A S SS A + ++E +AA P + G Q R+P G
Sbjct: 1221 ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKG 1280
Query: 171 TGQRRGSGSSPSAD-------QQGAQDREEEAAAAPAPTSRGHRTEKRK---PQQPQCRP 220
G + S + ++ Q + + A+ + E++K + R
Sbjct: 1281 AGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRK 1340
Query: 221 AGGTGQRRGSRSSPSADQQRAQDREE-------EAAAAPAPTSRGHRTEKRKPQQPQRRP 273
+ +R+ S P+A R++ +++ EA+ +P TS T K K ++ +
Sbjct: 1341 GWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTST---TSKGKAKRD--KA 1395
Query: 274 AGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQR 333
+G +++G G S QGA+D EE +LQ
Sbjct: 1396 SGDVKEKKGKG---SLGSQGAKDEPEE--------------------ELQ---------- 1422
Query: 334 RGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSP 393
+G G +Q + ++E+ + + +K+K ++ + + Q++
Sbjct: 1423 KGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1482
Query: 394 SADQ 397
+A+Q
Sbjct: 1483 TAEQ 1486
Score = 35.4 bits (80), Expect = 0.097
Identities = 28/135 (20%), Positives = 57/135 (42%), Gaps = 12/135 (8%)
Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
PR K++ +KL G+ + EKT + + + +G +++G GS S Q
Sbjct: 1359 PRSKKK----KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS---Q 1411
Query: 63 GAQDREEEA-----AAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGG 117
GA+D EE DQ + ++E+ + + +K+K + + +
Sbjct: 1412 GAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSES 1471
Query: 118 TGQRRGSRSSPSADQ 132
Q++ + +A+Q
Sbjct: 1472 PSQKKKKKKKKTAEQ 1486
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
[Homo sapiens]
Length = 1411
Score = 56.6 bits (135), Expect = 4e-08
Identities = 95/437 (21%), Positives = 154/437 (35%), Gaps = 72/437 (16%)
Query: 36 QQQPQCQPAGGTGQRRG-----------SGSSPSADQQGAQDREEEAAAAPAADQQRAQD 84
Q +P PA G Q+ G +S S+++ EEA AA A Q +
Sbjct: 500 QAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL 559
Query: 85 REEEAAAAPVPTSSGHR---------TEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRA 135
+ + A P T++ T+ ++ PAG + G P+ D +
Sbjct: 560 KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSS 619
Query: 136 Q--DREEEAAAAPVPT----SRGHRTEKRKRQQPQRRPAG-GTGQRRGSGSSPSADQQGA 188
+ D EEE V S G + + P + G GT + P+ Q A
Sbjct: 620 EESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKA 679
Query: 189 QDRE-----------EEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSAD 237
+ +E EEAAA+PA +T +K Q A +G+ S+P
Sbjct: 680 EKQEDSESSEEESDSEEAAASPAQV----KTSVKKTQAKANPAAARAPSAKGTISAPGKV 735
Query: 238 QQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGG----------TGQRRGSGYSP 287
A ++ + + P R + + P P+ G TG SG
Sbjct: 736 VTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSG--- 792
Query: 288 SADQQGAQDREEEAAAAPAPTSSGHR-------TEKRKRLQLQCQPAGGTG----QRRGS 336
S++++ + E E A P+ H+ ++ R P G TG Q
Sbjct: 793 SSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQ 852
Query: 337 GCSSSANQQGAQDREEEAA---AAPVPTSSGHRTEKRKPQQPQRRPA---AGTGQRRGSG 390
S S++++ D E AA A + R P P PA A + R+
Sbjct: 853 DDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARA 912
Query: 391 SSPSADQQRAQDREEEV 407
S +A ++ +E+V
Sbjct: 913 SESTARSSSSESEDEDV 929
Score = 45.1 bits (105), Expect = 1e-04
Identities = 91/453 (20%), Positives = 144/453 (31%), Gaps = 85/453 (18%)
Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPV 94
P++ P G TG + ++ EE + A Q + + + AA
Sbjct: 305 PRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASA 364
Query: 95 PTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHR 154
P R + PA Q G + S D + EA AA
Sbjct: 365 PAKESPRKGAAPAPPRKTGPAAAQVQV-GKQEEDSRSSSEESDSDREALAA-----MNAA 418
Query: 155 TEKRKRQQPQRRPAGGTGQ---RRGSG---------SSPSA-------DQQGAQDREEEA 195
K + PQ +PA G +G+G ++PSA D + + + ++
Sbjct: 419 QVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDS 478
Query: 196 AAAPAPTSRGHRTEKR----KPQQPQCRPAGGTGQRRG------------------SRSS 233
+ PT+ EK +P PA G Q+ G SS
Sbjct: 479 SDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESS 538
Query: 234 PSADQQRAQDREEEAAAAPA---PTSRG-----HRTEKRK-------PQQPQR-----RP 273
SAD + A A A PA P ++ + T K Q P++ P
Sbjct: 539 DSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSP 598
Query: 274 AGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPA---GGT 330
AG + G P+ D +++ + E + G K LQ++ G
Sbjct: 599 AGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSL 658
Query: 331 GQRRG----SGCSSSANQQGAQDRE-----------EEAAAAPVPTSSGHRTEKRKPQQP 375
GQ + Q A+ +E EEAAA+P + + + K
Sbjct: 659 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 718
Query: 376 QRRPAAGTGQRRGSGSSPSADQQRAQDREEEVR 408
R + G G +A Q Q +V+
Sbjct: 719 AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 751
Score = 39.7 bits (91), Expect = 0.005
Identities = 69/393 (17%), Positives = 140/393 (35%), Gaps = 29/393 (7%)
Query: 42 QPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHR 101
QP+ G G+ + S Q + P + + + E++ +S
Sbjct: 1018 QPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSS 1077
Query: 102 TEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQ 161
+ Q + T SR+ ++ A+ E++ A G+ T
Sbjct: 1078 GSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA 1137
Query: 162 QPQRRPAGGTGQRRGSGSSPSA---DQQGAQD-REEEAAAAPAPTSRGHRTEKRKPQQPQ 217
Q A S SS A D G Q+ + ++AA +P + G Q
Sbjct: 1138 NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKS 1197
Query: 218 CRPAGGTGQRRGSRSSPSADQQRA--------QDREEEAAAAPAPTSRGHRTEKRKPQQP 269
+P G G + S + ++ + + + +A+ T + K+
Sbjct: 1198 RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTT 1257
Query: 270 QRRPAGG--TGQRRGSGYSPSADQQGAQDREE-------EAAAAPAPTSSGHRTEKRKRL 320
+ G + +R+ SG P+A ++ +++ EA+ +P TS+ + + ++
Sbjct: 1258 KESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRD- 1316
Query: 321 QLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPA 380
+ +G +++G G S QGA+D EE + T G K ++ +++
Sbjct: 1317 ----KASGDVKEKKGKG---SLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSD 1369
Query: 381 AGTGQRRGSGSSPSADQQRAQDREEEVRKWKKR 413
+ A + +D E +K KK+
Sbjct: 1370 KRKKDKEKKEKKKKAKKASTKDSESPSQKKKKK 1402
Score = 37.7 bits (86), Expect = 0.019
Identities = 76/424 (17%), Positives = 150/424 (35%), Gaps = 73/424 (17%)
Query: 9 DTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDRE 68
D+ + L +S ++ + T LR + P+ Q A + S G+++
Sbjct: 1024 DSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDG 1083
Query: 69 EEAAAAPAA--------------DQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQP 114
E A +A ++ A+ E++ A SG+ T Q
Sbjct: 1084 EGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1143
Query: 115 AGGTGQRRGSRSSPSADQQRAQDREE----EAAAAPVPTSRGHRTEKRKRQQPQRRPAGG 170
A S SS A + ++E +AA P + G Q R+P G
Sbjct: 1144 ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKG 1203
Query: 171 TGQRRGSGSSPSAD-------QQGAQDREEEAAAAPAPTSRGHRTEKRK---PQQPQCRP 220
G + S + ++ Q + + A+ + E++K + R
Sbjct: 1204 AGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRK 1263
Query: 221 AGGTGQRRGSRSSPSADQQRAQDREE-------EAAAAPAPTSRGHRTEKRKPQQPQRRP 273
+ +R+ S P+A R++ +++ EA+ +P TS T K K ++ +
Sbjct: 1264 GWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTST---TSKGKAKRD--KA 1318
Query: 274 AGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQR 333
+G +++G G S QGA+D EE +LQ
Sbjct: 1319 SGDVKEKKGKG---SLGSQGAKDEPEE--------------------ELQ---------- 1345
Query: 334 RGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSP 393
+G G +Q + ++E+ + + +K+K ++ + + Q++
Sbjct: 1346 KGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1405
Query: 394 SADQ 397
+A+Q
Sbjct: 1406 TAEQ 1409
Score = 35.4 bits (80), Expect = 0.097
Identities = 28/135 (20%), Positives = 57/135 (42%), Gaps = 12/135 (8%)
Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
PR K++ +KL G+ + EKT + + + +G +++G GS S Q
Sbjct: 1282 PRSKKK----KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS---Q 1334
Query: 63 GAQDREEEA-----AAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGG 117
GA+D EE DQ + ++E+ + + +K+K + + +
Sbjct: 1335 GAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSES 1394
Query: 118 TGQRRGSRSSPSADQ 132
Q++ + +A+Q
Sbjct: 1395 PSQKKKKKKKKTAEQ 1409
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 56.6 bits (135), Expect = 4e-08
Identities = 95/437 (21%), Positives = 154/437 (35%), Gaps = 72/437 (16%)
Query: 36 QQQPQCQPAGGTGQRRGS-----------GSSPSADQQGAQDREEEAAAAPAADQQRAQD 84
Q +P PA G Q+ G +S S+++ EEA AA A Q +
Sbjct: 577 QAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL 636
Query: 85 REEEAAAAPVPTSSGHR---------TEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRA 135
+ + A P T++ T+ ++ PAG + G P+ D +
Sbjct: 637 KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSS 696
Query: 136 Q--DREEEAAAAPVPT----SRGHRTEKRKRQQPQRRPAG-GTGQRRGSGSSPSADQQGA 188
+ D EEE V S G + + P + G GT + P+ Q A
Sbjct: 697 EESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKA 756
Query: 189 QDRE-----------EEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSAD 237
+ +E EEAAA+PA +T +K Q A +G+ S+P
Sbjct: 757 EKQEDSESSEEESDSEEAAASPAQV----KTSVKKTQAKANPAAARAPSAKGTISAPGKV 812
Query: 238 QQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGG----------TGQRRGSGYSP 287
A ++ + + P R + + P P+ G TG SG
Sbjct: 813 VTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSG--- 869
Query: 288 SADQQGAQDREEEAAAAPAPTSSGHR-------TEKRKRLQLQCQPAGGTG----QRRGS 336
S++++ + E E A P+ H+ ++ R P G TG Q
Sbjct: 870 SSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQ 929
Query: 337 GCSSSANQQGAQDREEEAA---AAPVPTSSGHRTEKRKPQQPQRRPA---AGTGQRRGSG 390
S S++++ D E AA A + R P P PA A + R+
Sbjct: 930 DDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARA 989
Query: 391 SSPSADQQRAQDREEEV 407
S +A ++ +E+V
Sbjct: 990 SESTARSSSSESEDEDV 1006
Score = 55.8 bits (133), Expect = 7e-08
Identities = 79/392 (20%), Positives = 135/392 (34%), Gaps = 51/392 (13%)
Query: 46 GTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKR 105
GT + P+ Q A+ +E+ ++ +D EEAAA+P +
Sbjct: 738 GTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDS-------EEAAASPAQVKTSV----- 785
Query: 106 KRLQLQCQPAGGTG-QRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQ 164
K+ Q + PA +G+ S+P A ++ + + P R + + P
Sbjct: 786 KKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPA 845
Query: 165 RRPAGG----------TGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQ 214
P+ G TG SGSS +++ + E E A P+ + H+
Sbjct: 846 SVPSVGKAVATAAQAQTGPEEDSGSS---EEESDSEEEAETLAQVKPSGKTHQIRAALAP 902
Query: 215 QPQCRPAGGTGQRRGSRSSPSADQQRAQD-----REEEAAAAPAPTSRGHRTEKRKPQ-- 267
+ P G ++ PSA Q QD EE + AP + + P
Sbjct: 903 AKES-PRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIF 961
Query: 268 -QPQRRPAG----------GTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTE- 315
P R PAG + R+ +A ++ +E+ A + G RT
Sbjct: 962 VDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNV 1021
Query: 316 -----KRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKR 370
R+ + AG + + S S Q+G + + A TS + +
Sbjct: 1022 VTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQA 1081
Query: 371 KPQQPQRRPAAGTGQRRGSGSSPSADQQRAQD 402
K R+P Q+ S D + + D
Sbjct: 1082 KGTNKLRKPKLPEVQQATKAPESSDDSEDSSD 1113
Score = 45.1 bits (105), Expect = 1e-04
Identities = 91/453 (20%), Positives = 144/453 (31%), Gaps = 85/453 (18%)
Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPV 94
P++ P G TG + ++ EE + A Q + + + AA
Sbjct: 382 PRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASA 441
Query: 95 PTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHR 154
P R + PA Q G + S D + EA AA
Sbjct: 442 PAKESPRKGAAPAPPRKTGPAAAQVQV-GKQEEDSRSSSEESDSDREALAA-----MNAA 495
Query: 155 TEKRKRQQPQRRPAGGTGQ---RRGSG---------SSPSA-------DQQGAQDREEEA 195
K + PQ +PA G +G+G ++PSA D + + + ++
Sbjct: 496 QVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDS 555
Query: 196 AAAPAPTSRGHRTEKR----KPQQPQCRPAGGTGQRRG------------------SRSS 233
+ PT+ EK +P PA G Q+ G SS
Sbjct: 556 SDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESS 615
Query: 234 PSADQQRAQDREEEAAAAPA---PTSRG-----HRTEKRK-------PQQPQR-----RP 273
SAD + A A A PA P ++ + T K Q P++ P
Sbjct: 616 DSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSP 675
Query: 274 AGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPA---GGT 330
AG + G P+ D +++ + E + G K LQ++ G
Sbjct: 676 AGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSL 735
Query: 331 GQRRG----SGCSSSANQQGAQDRE-----------EEAAAAPVPTSSGHRTEKRKPQQP 375
GQ + Q A+ +E EEAAA+P + + + K
Sbjct: 736 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 795
Query: 376 QRRPAAGTGQRRGSGSSPSADQQRAQDREEEVR 408
R + G G +A Q Q +V+
Sbjct: 796 AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828
Score = 40.4 bits (93), Expect = 0.003
Identities = 77/421 (18%), Positives = 146/421 (34%), Gaps = 50/421 (11%)
Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAA-PAADQQ------------R 81
P+ P+ AG + + S S Q+G + + A PA Q R
Sbjct: 1029 PRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLR 1088
Query: 82 AQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRG--------SRSSPSADQQ 133
E A P SS + + G + SR+ ++
Sbjct: 1089 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEET 1148
Query: 134 RAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSA---DQQGAQD 190
A+ E++ A G+ T Q A S SS A D G Q+
Sbjct: 1149 AAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQE 1208
Query: 191 -REEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRA-------- 241
+ ++AA +P + G Q +P G G + S + ++ +
Sbjct: 1209 AKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPL 1268
Query: 242 QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGG--TGQRRGSGYSPSADQQGAQDREE 299
+ + +A+ T + K+ + G + +R+ SG P+A ++ +++
Sbjct: 1269 NEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKK 1328
Query: 300 -------EAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREE 352
EA+ +P TS+ + + ++ + +G +++G G S QGA+D E
Sbjct: 1329 LGAGEGGEASVSPEKTSTTSKGKAKRD-----KASGDVKEKKGKG---SLGSQGAKDEPE 1380
Query: 353 EAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEEVRKWKK 412
E + T G K ++ +++ + A + +D E +K KK
Sbjct: 1381 EELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKK 1440
Query: 413 R 413
+
Sbjct: 1441 K 1441
Score = 37.7 bits (86), Expect = 0.019
Identities = 76/424 (17%), Positives = 150/424 (35%), Gaps = 73/424 (17%)
Query: 9 DTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDRE 68
D+ + L +S ++ + T LR + P+ Q A + S G+++
Sbjct: 1063 DSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDG 1122
Query: 69 EEAAAAPAA--------------DQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQP 114
E A +A ++ A+ E++ A SG+ T Q
Sbjct: 1123 EGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1182
Query: 115 AGGTGQRRGSRSSPSADQQRAQDREE----EAAAAPVPTSRGHRTEKRKRQQPQRRPAGG 170
A S SS A + ++E +AA P + G Q R+P G
Sbjct: 1183 ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKG 1242
Query: 171 TGQRRGSGSSPSAD-------QQGAQDREEEAAAAPAPTSRGHRTEKRK---PQQPQCRP 220
G + S + ++ Q + + A+ + E++K + R
Sbjct: 1243 AGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRK 1302
Query: 221 AGGTGQRRGSRSSPSADQQRAQDREE-------EAAAAPAPTSRGHRTEKRKPQQPQRRP 273
+ +R+ S P+A R++ +++ EA+ +P TS T K K ++ +
Sbjct: 1303 GWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTST---TSKGKAKRD--KA 1357
Query: 274 AGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQR 333
+G +++G G S QGA+D EE +LQ
Sbjct: 1358 SGDVKEKKGKG---SLGSQGAKDEPEE--------------------ELQ---------- 1384
Query: 334 RGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSP 393
+G G +Q + ++E+ + + +K+K ++ + + Q++
Sbjct: 1385 KGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1444
Query: 394 SADQ 397
+A+Q
Sbjct: 1445 TAEQ 1448
Score = 35.4 bits (80), Expect = 0.097
Identities = 28/135 (20%), Positives = 57/135 (42%), Gaps = 12/135 (8%)
Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
PR K++ +KL G+ + EKT + + + +G +++G GS S Q
Sbjct: 1321 PRSKKK----KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS---Q 1373
Query: 63 GAQDREEEA-----AAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGG 117
GA+D EE DQ + ++E+ + + +K+K + + +
Sbjct: 1374 GAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSES 1433
Query: 118 TGQRRGSRSSPSADQ 132
Q++ + +A+Q
Sbjct: 1434 PSQKKKKKKKKTAEQ 1448
>gi|199559779 coiled-coil domain containing 8 [Homo sapiens]
Length = 538
Score = 56.2 bits (134), Expect = 5e-08
Identities = 68/294 (23%), Positives = 108/294 (36%), Gaps = 37/294 (12%)
Query: 42 QPAGGTGQRRGSGSSPSA-----DQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPT 96
Q + G +RR G +P A + + A E A + A + DR A VP
Sbjct: 200 QVSWGKLKRRVKGWAPRAGPGVGEARLASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQ 259
Query: 97 SSGHRTEK-------RKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQ---DREEEAAA-- 144
+S R R+R + Q P G + +AD QR + D+ E AA
Sbjct: 260 ASPRRWRPKINWASFRRRRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQ 319
Query: 145 -APVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTS 203
A P +G +R++ G G+ ++ + ++ A ++ EA A
Sbjct: 320 RAGAPADQGAEAADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQG 379
Query: 204 RGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEK 263
+ E+ Q PA + S D QR + ++ APA +
Sbjct: 380 TDNHREEAADNQRAEAPA--------DQGSEVTDNQREEAVHDQRERAPA-------VQG 424
Query: 264 RKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKR 317
Q+ Q R GQR + ++ A G Q+ E AA T+ G R K+
Sbjct: 425 ADNQRAQAR----AGQRAEAAHNQRAGAPGIQEAEVSAAQGTTGTAPGARARKQ 474
Score = 30.8 bits (68), Expect = 2.4
Identities = 44/189 (23%), Positives = 67/189 (35%), Gaps = 28/189 (14%)
Query: 231 RSSPSADQQRAQDREEEAA---AAPAPTSRGHRTEKRK----PQQPQRR---PAGGTGQR 280
R+ P + R E+A +AP TS G R PQ RR R
Sbjct: 216 RAGPGVGEARLASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQASPRRWRPKINWASFR 275
Query: 281 RGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSS 340
R + QGA ++ G + ++ + Q G G +R +G +
Sbjct: 276 RRRKEQTAPTGQGADIEADQG---------GEAADSQREEAIADQREGAAGNQR-AGAPA 325
Query: 341 SANQQGAQDREEEAA---AAPVPTSSG-----HRTEKRKPQQPQRRPAAGTGQRRGSGSS 392
+ A ++ EEAA A P G ++ E+ Q PA Q +
Sbjct: 326 DQGAEAADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHRE 385
Query: 393 PSADQQRAQ 401
+AD QRA+
Sbjct: 386 EAADNQRAE 394
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.120 0.339
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,816,956
Number of Sequences: 37866
Number of extensions: 1455772
Number of successful extensions: 15688
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 229
Number of HSP's successfully gapped in prelim test: 1386
Number of HSP's that attempted gapping in prelim test: 8526
Number of HSP's gapped (non-prelim): 5717
length of query: 417
length of database: 18,247,518
effective HSP length: 105
effective length of query: 312
effective length of database: 14,271,588
effective search space: 4452735456
effective search space used: 4452735456
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.