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Search of human proteins with 119372310
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|119372310 glycine receptor, alpha 1 isoform 2 precursor
[Homo sapiens]
(449 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo... 915 0.0
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo... 908 0.0
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens] 759 0.0
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens] 752 0.0
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens] 702 0.0
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] 700 0.0
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] 700 0.0
gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens] 616 e-176
gi|4504023 glycine receptor, beta [Homo sapiens] 357 2e-98
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p... 286 3e-77
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is... 286 3e-77
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso... 285 4e-77
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso... 285 4e-77
gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta pre... 285 8e-77
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s... 283 3e-76
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs... 283 3e-76
gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2 is... 280 1e-75
gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo s... 273 2e-73
gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1 [Hom... 273 2e-73
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs... 272 4e-73
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr... 272 5e-73
gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor... 271 1e-72
gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 269 3e-72
gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 269 3e-72
gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 269 3e-72
gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 269 3e-72
gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 269 3e-72
gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 269 3e-72
gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 p... 269 3e-72
gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2 prec... 266 3e-71
>gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 449
Score = 915 bits (2366), Expect = 0.0
Identities = 449/449 (100%), Positives = 449/449 (100%)
Query: 1 MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNF 60
MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNF
Sbjct: 1 MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNF 60
Query: 61 KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS 120
KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS
Sbjct: 61 KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS 120
Query: 121 IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC
Sbjct: 121 IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
Query: 181 IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA 240
IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA
Sbjct: 181 IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA 240
Query: 241 RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRA 300
RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRA
Sbjct: 241 RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRA 300
Query: 301 SLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKEDEAGEG 360
SLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKEDEAGEG
Sbjct: 301 SLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKEDEAGEG 360
Query: 361 RFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISR 420
RFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISR
Sbjct: 361 RFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISR 420
Query: 421 IGFPMAFLIFNMFYWIIYKIVRREDVHNQ 449
IGFPMAFLIFNMFYWIIYKIVRREDVHNQ
Sbjct: 421 IGFPMAFLIFNMFYWIIYKIVRREDVHNQ 449
>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 457
Score = 908 bits (2347), Expect = 0.0
Identities = 449/457 (98%), Positives = 449/457 (98%), Gaps = 8/457 (1%)
Query: 1 MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNF 60
MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNF
Sbjct: 1 MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNF 60
Query: 61 KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS 120
KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS
Sbjct: 61 KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS 120
Query: 121 IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC
Sbjct: 121 IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC 180
Query: 181 IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA 240
IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA
Sbjct: 181 IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA 240
Query: 241 RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRA 300
RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRA
Sbjct: 241 RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRA 300
Query: 301 SLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHK------- 353
SLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHK
Sbjct: 301 SLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLF 360
Query: 354 -EDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRA 412
EDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRA
Sbjct: 361 QEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRA 420
Query: 413 KKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ 449
KKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ
Sbjct: 421 KKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ 457
>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
Length = 449
Score = 759 bits (1959), Expect = 0.0
Identities = 370/440 (84%), Positives = 402/440 (91%), Gaps = 7/440 (1%)
Query: 10 YLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSC 69
Y WE + SL A+KE ++ARS PMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+C
Sbjct: 15 YFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTC 74
Query: 70 NIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFA 129
NIFINSFGSIAETTMDYRVNIFLRQ+WNDPRLAY+EYPDDSLDLDPSMLDSIWKPDLFFA
Sbjct: 75 NIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFA 134
Query: 130 NEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGY 189
NEKGA+FHE+TTDNKLLRI +NGNVLYSIR+TLTL+CPMDLKNFPMDVQTCIMQLESFGY
Sbjct: 135 NEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGY 194
Query: 190 TMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMG 249
TMNDLIFEWQ++ VQVA+GLTLPQF+LKEEKDLRYCTKHYNTGKFTCIE RFHLERQMG
Sbjct: 195 TMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMG 254
Query: 250 YYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVK 309
YYLIQMYIPSLLIVILSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVK
Sbjct: 255 YYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVK 314
Query: 310 AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKEDEAGEGRFNFSAYGM 369
AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKR+ +K+DE E RF+F+AYGM
Sbjct: 315 AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRK-NKDDEVRESRFSFTAYGM 373
Query: 370 GPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLI 429
GP CLQAKDG++ KG N +P KSP+EMRK+FI RAKKID ISR FP+AFLI
Sbjct: 374 GP-CLQAKDGMTPKGPN-----HPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLI 427
Query: 430 FNMFYWIIYKIVRREDVHNQ 449
FN+FYW+IYKI+R ED+H Q
Sbjct: 428 FNIFYWVIYKILRHEDIHQQ 447
>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
Length = 464
Score = 752 bits (1942), Expect = 0.0
Identities = 370/454 (81%), Positives = 401/454 (88%), Gaps = 20/454 (4%)
Query: 10 YLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSC 69
Y WE + SL A+KE ++ARS PMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+C
Sbjct: 15 YFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTC 74
Query: 70 NIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFA 129
NIFINSFGSIAETTMDYRVNIFLRQ+WNDPRLAY+EYPDDSLDLDPSMLDSIWKPDLFFA
Sbjct: 75 NIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFA 134
Query: 130 NEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGY 189
NEKGA+FHE+TTDNKLLRI +NGNVLYSIR+TLTL+CPMDLKNFPMDVQTCIMQLESFGY
Sbjct: 135 NEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGY 194
Query: 190 TMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMG 249
TMNDLIFEWQ++ VQVA+GLTLPQF+LKEEKDLRYCTKHYNTGKFTCIE RFHLERQMG
Sbjct: 195 TMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMG 254
Query: 250 YYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVK 309
YYLIQMYIPSLLIVILSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVK
Sbjct: 255 YYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVK 314
Query: 310 AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKE--------------D 355
AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKR++ E D
Sbjct: 315 AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDD 374
Query: 356 EAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKI 415
E E RF+F+AYGMGP CLQAKDG++ KG N +P KSP+EMRK+FI RAKKI
Sbjct: 375 EVRESRFSFTAYGMGP-CLQAKDGMTPKGPN-----HPVQVMPKSPDEMRKVFIDRAKKI 428
Query: 416 DKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ 449
D ISR FP+AFLIFN+FYW+IYKI+R ED+H Q
Sbjct: 429 DTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQ 462
>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
Length = 452
Score = 702 bits (1811), Expect = 0.0
Identities = 343/427 (80%), Positives = 376/427 (88%), Gaps = 7/427 (1%)
Query: 25 EAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTM 84
++ + + + +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+CNIFINSFGSIAETTM
Sbjct: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 90
Query: 85 DYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNK 144
DYRVNIFLRQQWND RLAY+EYPDDSLDLDPSMLDSIWKPDLFFANEKGA+FH++TTDNK
Sbjct: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
Query: 145 LLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAV 204
LLRIS+NG VLYSIR+TLTL+CPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW G V
Sbjct: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
Query: 205 QVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVI 264
QVA+GLTLPQFILKEEK+L YCTKHYNTGKFTCIE +FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
Query: 265 LSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 324
LSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
Query: 325 ALLEYAAVNFVSRQHKELLRFRR--KRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISV 382
ALLEYAAVNFVSRQHKE LR RR KR++ +ED E RFNFS YGMG CLQ KDG +V
Sbjct: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMG-HCLQVKDGTAV 389
Query: 383 KGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVR 442
K + NP P P K + ++K F+ RAK+ID ISR FP+AFLIFN+FYWI YKI+R
Sbjct: 390 K----ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIR 445
Query: 443 REDVHNQ 449
EDVH +
Sbjct: 446 HEDVHKK 452
>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 700 bits (1806), Expect = 0.0
Identities = 341/427 (79%), Positives = 375/427 (87%), Gaps = 7/427 (1%)
Query: 25 EAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTM 84
++ + + + +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+CNIFINSFGS+ ETTM
Sbjct: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTM 90
Query: 85 DYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNK 144
DYRVNIFLRQQWND RLAY+EYPDDSLDLDPSMLDSIWKPDLFFANEKGA+FH++TTDNK
Sbjct: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
Query: 145 LLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAV 204
LLRIS+NG VLYSIR+TLTL+CPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW G V
Sbjct: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
Query: 205 QVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVI 264
QVA+GLTLPQFILKEEK+L YCTKHYNTGKFTCIE +FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
Query: 265 LSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 324
LSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
Query: 325 ALLEYAAVNFVSRQHKELLRFRR--KRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISV 382
ALLEYAAVNFVSRQHKE LR RR KR++ +ED E RFNFS YGMG CLQ KDG +V
Sbjct: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMG-HCLQVKDGTAV 389
Query: 383 KGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVR 442
K + NP P P K + ++K F+ RAK+ID ISR FP+AFLIFN+FYWI YKI+R
Sbjct: 390 K----ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIR 445
Query: 443 REDVHNQ 449
EDVH +
Sbjct: 446 HEDVHKK 452
>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 700 bits (1806), Expect = 0.0
Identities = 341/427 (79%), Positives = 375/427 (87%), Gaps = 7/427 (1%)
Query: 25 EAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTM 84
++ + + + +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+CNIFINSFGS+ ETTM
Sbjct: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTM 90
Query: 85 DYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNK 144
DYRVNIFLRQQWND RLAY+EYPDDSLDLDPSMLDSIWKPDLFFANEKGA+FH++TTDNK
Sbjct: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
Query: 145 LLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAV 204
LLRIS+NG VLYSIR+TLTL+CPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW G V
Sbjct: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
Query: 205 QVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVI 264
QVA+GLTLPQFILKEEK+L YCTKHYNTGKFTCIE +FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
Query: 265 LSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 324
LSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
Query: 325 ALLEYAAVNFVSRQHKELLRFRR--KRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISV 382
ALLEYAAVNFVSRQHKE LR RR KR++ +ED E RFNFS YGMG CLQ KDG +V
Sbjct: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMG-HCLQVKDGTAV 389
Query: 383 KGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVR 442
K + NP P P K + ++K F+ RAK+ID ISR FP+AFLIFN+FYWI YKI+R
Sbjct: 390 K----ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIR 445
Query: 443 REDVHNQ 449
EDVH +
Sbjct: 446 HEDVHKK 452
>gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens]
Length = 417
Score = 616 bits (1588), Expect = e-176
Identities = 307/393 (78%), Positives = 341/393 (86%), Gaps = 9/393 (2%)
Query: 22 ASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAE 81
A +E ++ +PMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+CNIFINSF SI +
Sbjct: 28 AKEEVKSGTKGSQPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFSSITK 87
Query: 82 TTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITT 141
TTMDYRVN+FLRQQWNDPRL+Y EYPDDSLDLDPSMLDSIWKPDLFFANEKGA+FHE+TT
Sbjct: 88 TTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTT 147
Query: 142 DNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQ 201
DNKLLRI +NGNVLYSIR+TL L+C MDLKNFPMD+QTC MQLESFGYTM DL+FEW E
Sbjct: 148 DNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCTMQLESFGYTMKDLVFEWLED 207
Query: 202 G-AVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSL 260
AVQVA+GLTLPQFIL++EKDL CTKHYNTGKFTCIE +FHLERQMGYYLIQMYIPSL
Sbjct: 208 APAVQVAEGLTLPQFILRDEKDLGCCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSL 267
Query: 261 LIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLL 320
LIVILSW+SFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLL
Sbjct: 268 LIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLL 327
Query: 321 FVFSALLEYAAVNFVSRQHKELLRFRRKRRHHK--EDEAGEGRFNFSAYGMGPACLQAKD 378
FVF+ALLEYAA+NFVSRQHKE +R RR++R + ED E RF F YG+G CLQA+D
Sbjct: 328 FVFAALLEYAAINFVSRQHKEFIRLRRRQRRQRLEEDIIQESRFYFRGYGLG-HCLQARD 386
Query: 379 GISVKGANNSNTTNP-PPAP-SKSPEEMRKLFI 409
G ++G S +P PPAP + E RKL++
Sbjct: 387 GGPMEG---SGIYSPQPPAPLLREGETTRKLYV 416
>gi|4504023 glycine receptor, beta [Homo sapiens]
Length = 497
Score = 357 bits (915), Expect = 2e-98
Identities = 208/457 (45%), Positives = 272/457 (59%), Gaps = 70/457 (15%)
Query: 37 SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQW 96
S S+ L++L+ YD RIRPNFKG PV+V NIFINSFGSI ETTMDYRVNIFLRQ+W
Sbjct: 55 STSNILNRLL---VSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKW 111
Query: 97 NDPRLAYNE--YPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNV 154
NDPRL D+L +DP+M +WKPDLFFANEK A+FH++T +N LL I R+G+V
Sbjct: 112 NDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDV 171
Query: 155 LYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQ 214
L S+R+++TL+CP+DL FPMD Q C MQLESFGYT +DL F WQ VQ+ + + LPQ
Sbjct: 172 LVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQL-EKIALPQ 230
Query: 215 FILKEEKDLRY--CTKHYN-TGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFW 271
F +K+E D+ Y CTK+Y TG +TC+E F L RQ+G+Y++ +Y P+LLIV+LSW+SFW
Sbjct: 231 FDIKKE-DIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFW 289
Query: 272 INMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAA 331
IN DA+ ARV LGI +VL++ ++ + A LPKVSYVKA+D+W+ CLLF F++L+EYA
Sbjct: 290 INPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAV 349
Query: 332 V----NFVSRQHKELLRFRRKRR---------------------HHKEDEAGEGR----- 361
V N R E R + + H + GE R
Sbjct: 350 VQVMLNNPKRVEAEKARIAKAEQADGKGGNVAKKNTVNGTGTPVHISTLQVGETRCKKVC 409
Query: 362 --------------------FNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSP 401
F S Y ++ +G+ A N+ PPPA P
Sbjct: 410 TSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKSQAKNNK--KPPPAKPVIP 467
Query: 402 EEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
AK+ID +R FP FL FN+ YW IY
Sbjct: 468 --------TAAKRIDLYARALFPFCFLFFNVIYWSIY 496
>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
precursor [Homo sapiens]
Length = 474
Score = 286 bits (732), Expect = 3e-77
Identities = 164/451 (36%), Positives = 247/451 (54%), Gaps = 44/451 (9%)
Query: 29 ARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRV 88
A S +P + S + + GYD R+RP+F GPPV+V I + S ++E MDY +
Sbjct: 25 AHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTL 84
Query: 89 NIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRI 148
++ +Q W D RL+Y+ P + L LD + D +W PD +F N+K + H +T N+++R+
Sbjct: 85 TMYFQQSWKDKRLSYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRL 143
Query: 149 SRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQE-QGAVQVA 207
+G VLY +RIT T AC MDL+ +P+D Q C +++ES+GYT +D+ F W +GAV
Sbjct: 144 HPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGV 203
Query: 208 DGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSW 267
+ + LPQF + + K + + + TG + + F L+R +GY+++Q Y+PS LI ILSW
Sbjct: 204 NKIELPQFSIVDYKMVSKKVE-FTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSW 262
Query: 268 ISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALL 327
+SFWIN DA+ ARV LGITTVLTMTT S+ R +LPK+ YVKAIDI++ C +FVF ALL
Sbjct: 263 VSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALL 322
Query: 328 EYAAVNFV----------SRQHKELLRFRRKRRHHKEDEAGEGRFNFSA----------- 366
EYA VN++ + + + + K +K G S
Sbjct: 323 EYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSE 382
Query: 367 ------------YGMGPACLQAKDGISVKGANNSNTTNPPPAPSK-------SPEEMRKL 407
Y A +Q + +S + A + PSK S +++
Sbjct: 383 VLTSVSDPKATMYSYDSASIQYRKPLSSREA-YGRALDRHGVPSKGRIRRRASQLKVKIP 441
Query: 408 FIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
+ IDK SR+ FP+ F +FN+ YW+ Y
Sbjct: 442 DLTDVNSIDKWSRMFFPITFSLFNVVYWLYY 472
>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 2 precursor [Homo sapiens]
Length = 473
Score = 286 bits (731), Expect = 3e-77
Identities = 169/465 (36%), Positives = 250/465 (53%), Gaps = 47/465 (10%)
Query: 16 VFFSLAASKEAEAARSAPKPMSPS---DFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIF 72
++ S RS P + S + +DKL+ GYD R+RP+F GPPV V NI
Sbjct: 12 IWLSWTLGTRGSEPRSVNDPGNMSFVKETVDKLL---KGYDIRLRPDFGGPPVCVGMNID 68
Query: 73 INSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEK 132
I S ++E MDY + ++ +Q W D RLAY+ P + L LD + D +W PD +F N+K
Sbjct: 69 IASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLN-LTLDNRVADQLWVPDTYFLNDK 127
Query: 133 GAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMN 192
+ H +T N+++R+ +G VLY +RIT T AC MDL+ +P+D Q C +++ES+GYT +
Sbjct: 128 KSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD 187
Query: 193 DLIFEWQE-QGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYY 251
D+ F W+ AV + + LPQF + E + L + TG + + F L+R +GY+
Sbjct: 188 DIEFYWRGGDKAVTGVERIELPQFSIVEHR-LVSRNVVFATGAYPRLSLSFRLKRNIGYF 246
Query: 252 LIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAI 311
++Q Y+PS+LI ILSW+SFWIN DA+ ARV LGITTVLTMTT ++ R +LPK+ YVKAI
Sbjct: 247 ILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAI 306
Query: 312 DIWMAVCLLFVFSALLEYAAVNFV--SRQHKELLRFRRKRRHHKEDEAGEGRFNFSAYG- 368
D+++ C +FVF ALLEYA VN++ R + + K K D + A+G
Sbjct: 307 DMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGN 366
Query: 369 MGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQR----------------- 411
+ L+ + ++ +T N + S + RK + R
Sbjct: 367 ILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKT 426
Query: 412 ------------------AKKIDKISRIGFPMAFLIFNMFYWIIY 438
ID+ SRI FP F +FN+ YW+ Y
Sbjct: 427 HLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYY 471
>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 1 precursor [Homo sapiens]
Length = 473
Score = 285 bits (730), Expect = 4e-77
Identities = 164/436 (37%), Positives = 241/436 (55%), Gaps = 44/436 (10%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
+DKL+ GYD R+RP+F GPPV V NI I S ++E MDY + ++ +Q W D RL
Sbjct: 41 VDKLL---KGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRL 97
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
AY+ P +L LD + D +W PD +F N+K + H +T N+++R+ +G VLY +RIT
Sbjct: 98 AYSGIP-LNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ-EQGAVQVADGLTLPQFILKEE 220
T AC MDL+ +P+D Q C +++ES+GYT +D+ F W+ AV + + LPQF + E
Sbjct: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216
Query: 221 KDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPAR 280
+ L + TG + + F L+R +GY+++Q Y+PS+LI ILSW+SFWIN DA+ AR
Sbjct: 217 R-LVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAAR 275
Query: 281 VGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV--SRQ 338
V LGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FVF ALLEYA VN++ R
Sbjct: 276 VALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRG 335
Query: 339 HKELLRFRRKRRHHKEDEAGEGRFNFSAYG-MGPACLQAKDGISVKGANNSNTTNPPPAP 397
+ + K K D + A+G + L+ + ++ +T N +
Sbjct: 336 PQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISF 395
Query: 398 SKSPEEMRKLFIQR-----------------------------------AKKIDKISRIG 422
S + RK + R ID+ SRI
Sbjct: 396 DNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIV 455
Query: 423 FPMAFLIFNMFYWIIY 438
FP F +FN+ YW+ Y
Sbjct: 456 FPFTFSLFNLVYWLYY 471
>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 2 [Homo sapiens]
Length = 474
Score = 285 bits (730), Expect = 4e-77
Identities = 170/461 (36%), Positives = 249/461 (54%), Gaps = 57/461 (12%)
Query: 26 AEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMD 85
A A+S P + S + + GYD R+RP+F GPPV V NI I S ++E MD
Sbjct: 21 AVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMD 80
Query: 86 YRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKL 145
Y + ++ +Q W D RL+YN P + L LD + D +W PD +F N+K + H +T N++
Sbjct: 81 YTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 139
Query: 146 LRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ-EQGAV 204
+R+ +G VLY +RIT T AC MDL+ +P+D Q C +++ES+GYT +D+ F W+ + AV
Sbjct: 140 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAV 199
Query: 205 QVADGLTLPQFILKEEKDLRYCTKH--YNTGKFTCIEARFHLERQMGYYLIQMYIPSLLI 262
+ LPQF + D + TK ++TG + + F L+R +GY+++Q Y+PS+LI
Sbjct: 200 TGVTKIELPQFSIV---DYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILI 256
Query: 263 VILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFV 322
ILSW+SFWIN DA+ ARV LGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FV
Sbjct: 257 TILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFV 316
Query: 323 FSALLEYAAVNFVSRQHKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGP------ACLQA 376
F ALLEYA VN++ R+K+ K A + M P + L+
Sbjct: 317 FMALLEYALVNYIFFGRGPQ---RQKKAAEKAASANNEKMRLDVNKMDPHENILLSTLEI 373
Query: 377 KDGI----SVKGANNSNTTNPPPAPSKSPEEMRKLFIQR--------------------- 411
K+ + +V G + +T A S + RK + R
Sbjct: 374 KNEMATSEAVMGLGDPRST--MLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRR 431
Query: 412 --------------AKKIDKISRIGFPMAFLIFNMFYWIIY 438
ID+ SRI FP+ F FN+ YW+ Y
Sbjct: 432 RASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 472
>gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta
precursor [Homo sapiens]
Length = 452
Score = 285 bits (728), Expect = 8e-77
Identities = 159/412 (38%), Positives = 228/412 (55%), Gaps = 15/412 (3%)
Query: 41 FLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPR 100
+L L G +GY RP GPPVNV+ + + S I+E M+Y + +FL Q W D R
Sbjct: 40 WLPNLDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSR 99
Query: 101 LAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRI 160
L+YN + +++L LD +D +W PD F N K A FH++T +NKL+R+ +G +LYSIRI
Sbjct: 100 LSYN-HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRI 158
Query: 161 TLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQE-QGAVQVADGLTLPQFILKE 219
T T+AC MDL +PMD Q C++ LES+GY+ D+++ W E Q + D L L QF +
Sbjct: 159 TSTVACDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITS 218
Query: 220 EKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPA 279
+ + G+F + FHL R G Y+IQ Y+PS+L+V +SW+SFWI+ A PA
Sbjct: 219 YRFTTELMNFKSAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPA 278
Query: 280 RVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQH 339
RV LGITTVLTMTT +R+SLP+ S +KA+D++ +C +FVF+AL+EYA +F +
Sbjct: 279 RVSLGITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYR 338
Query: 340 KELLRFRRKRRHHKEDEAGEG--RFNFSAYGMGPACLQAKDGISVK----------GANN 387
K+ + R E + F+ SA G+ ++ V G
Sbjct: 339 KKQKAKVKVSRPRAEMDVRNAIVLFSLSAAGVTQELAISRRQRRVPGNLMGSYRSVGVET 398
Query: 388 SNTTNPPPAPSKSPEEMR-KLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
T A S +R +L A ID +R FP AF N+ YW Y
Sbjct: 399 GETKKEGAARSGGQGGIRARLRPIDADTIDIYARAVFPAAFAAVNVIYWAAY 450
>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
sapiens]
Length = 451
Score = 283 bits (723), Expect = 3e-76
Identities = 162/416 (38%), Positives = 245/416 (58%), Gaps = 26/416 (6%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V NI++ SFG +++T M+Y +++F RQ+W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P + L L+ M IW PD FF N K + H +T NKLLRI +G +LY++R+T
Sbjct: 103 KFKG-PMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEW--QEQGAVQVA-DGLTLPQFILK 218
+ CPM L++FPMD +C ++ S+ YT +++ + W +VQVA DG L Q+ L
Sbjct: 162 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 221
Query: 219 EEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAP 278
+ + K +TG++T + A FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ P
Sbjct: 222 GQSIGKETIKS-STGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 280
Query: 279 ARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ 338
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++
Sbjct: 281 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
Query: 339 -----HKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQ---AKDGISVKGANNSNT 390
K ++ ++K E +AY + A +KD + + ++ T
Sbjct: 341 GWAWDGKSVVNDKKK-------EKASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATT 393
Query: 391 TNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDV 446
P P P E +K F KID++SRI FP+ F FN+ YW Y + RE V
Sbjct: 394 PEPNKKPENKPAEAKKTF-NSVSKIDRMSRIVFPVLFGTFNLVYWATY--LNREPV 446
>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
[Homo sapiens]
Length = 451
Score = 283 bits (723), Expect = 3e-76
Identities = 162/416 (38%), Positives = 245/416 (58%), Gaps = 26/416 (6%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V NI++ SFG +++T M+Y +++F RQ+W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P + L L+ M IW PD FF N K + H +T NKLLRI +G +LY++R+T
Sbjct: 103 KFKG-PMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEW--QEQGAVQVA-DGLTLPQFILK 218
+ CPM L++FPMD +C ++ S+ YT +++ + W +VQVA DG L Q+ L
Sbjct: 162 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 221
Query: 219 EEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAP 278
+ + K +TG++T + A FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ P
Sbjct: 222 GQSIGKETIKS-STGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 280
Query: 279 ARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ 338
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++
Sbjct: 281 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
Query: 339 -----HKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQ---AKDGISVKGANNSNT 390
K ++ ++K E +AY + A +KD + + ++ T
Sbjct: 341 GWAWDGKSVVNDKKK-------EKASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATT 393
Query: 391 TNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDV 446
P P P E +K F KID++SRI FP+ F FN+ YW Y + RE V
Sbjct: 394 PEPNKKPENKPAEAKKTF-NSVSKIDRMSRIVFPVLFGTFNLVYWATY--LNREPV 446
>gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 1 [Homo sapiens]
Length = 512
Score = 280 bits (717), Expect = 1e-75
Identities = 141/313 (45%), Positives = 204/313 (65%), Gaps = 7/313 (2%)
Query: 26 AEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMD 85
A A+S P + S + + GYD R+RP+F GPPV V NI I S ++E MD
Sbjct: 21 AVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMD 80
Query: 86 YRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKL 145
Y + ++ +Q W D RL+YN P + L LD + D +W PD +F N+K + H +T N++
Sbjct: 81 YTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 139
Query: 146 LRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ-EQGAV 204
+R+ +G VLY +RIT T AC MDL+ +P+D Q C +++ES+GYT +D+ F W+ + AV
Sbjct: 140 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAV 199
Query: 205 QVADGLTLPQFILKEEKDLRYCTKH--YNTGKFTCIEARFHLERQMGYYLIQMYIPSLLI 262
+ LPQF + D + TK ++TG + + F L+R +GY+++Q Y+PS+LI
Sbjct: 200 TGVTKIELPQFSIV---DYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILI 256
Query: 263 VILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFV 322
ILSW+SFWIN DA+ ARV LGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FV
Sbjct: 257 TILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFV 316
Query: 323 FSALLEYAAVNFV 335
F ALLEYA VN++
Sbjct: 317 FMALLEYALVNYI 329
Score = 33.5 bits (75), Expect = 0.40
Identities = 13/24 (54%), Positives = 17/24 (70%)
Query: 415 IDKISRIGFPMAFLIFNMFYWIIY 438
ID+ SRI FP+ F FN+ YW+ Y
Sbjct: 487 IDRWSRIFFPVVFSFFNIVYWLYY 510
>gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo
sapiens]
Length = 440
Score = 273 bits (699), Expect = 2e-73
Identities = 152/402 (37%), Positives = 231/402 (57%), Gaps = 21/402 (5%)
Query: 49 TSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPD 108
T+GY+ +RPNF G PV ++ + I S SI+E+ MDY I+LRQ+W D RL + +
Sbjct: 45 TAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEG--N 102
Query: 109 DSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPM 168
S LD +++ +W PD + K + HE+T N+L+R+ NG VLY++RIT T+AC M
Sbjct: 103 KSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNM 162
Query: 169 DLKNFPMDVQTCIMQLESFGYTMNDLIFEW-QEQGAVQVADGLTLPQFILKEEKDLRYCT 227
DL +PMD QTC +QLES+GY ND+ F W + +V+ + L L Q+ ++ RY T
Sbjct: 163 DLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIE-----RYFT 217
Query: 228 ----KHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGL 283
TG +T + +F L R + Y++++ Y+PS +V+LSW+SFWI++D+ PAR +
Sbjct: 218 LVTRSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCI 277
Query: 284 GITTVLTMTTQSSGSRASLPKVS-YVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKEL 342
G+TTVL+MTT GSR SLP + ++KAID+++ +C FVF ALLEYA ++ S Q ++
Sbjct: 278 GVTTVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQ--QM 335
Query: 343 LRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSK--S 400
R E+ + N S A IS + S+ T K
Sbjct: 336 AAKDRGTTKEVEEVSITNIINSSISSFKRKISFASIEISSDNVDYSDLTMKTSDKFKFVF 395
Query: 401 PEEMRKLF----IQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
E+M ++ IQ +D S++ FP+ F++ N+FYW Y
Sbjct: 396 REKMGRIVDYFTIQNPSNVDHYSKLLFPLIFMLANVFYWAYY 437
>gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1 [Homo
sapiens]
Length = 479
Score = 273 bits (698), Expect = 2e-73
Identities = 151/421 (35%), Positives = 244/421 (57%), Gaps = 17/421 (4%)
Query: 30 RSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVN 89
RS SP ++L+ R +D +RP F GP + V ++ + S SI+E MD+ +
Sbjct: 63 RSPDITKSPLTKSEQLL-RIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMT 121
Query: 90 IFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRIS 149
++LR W D RL++ + S+ D ++ IW PD+FF + K + H+ TTDN +LR+
Sbjct: 122 LYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQ 181
Query: 150 RNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQE-QGAVQVAD 208
+G VLYS+R+T+T C MD FP+D QTC +++ES+ YT +DL+ W++ +++ +
Sbjct: 182 PDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDE 241
Query: 209 GLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWI 268
++L QF+++E + +TG + + F L R + ++L+Q Y P+ L+V+LSW+
Sbjct: 242 RISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWV 301
Query: 269 SFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLE 328
SFWI+ A PARV LGITTVLTM+T +G AS+P+VSY+KA+DI++ V +FVF ++LE
Sbjct: 302 SFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLE 361
Query: 329 YAAVNFVSR-QHKELLRFRRK----------RRHHKEDEAGEGRFNFSAYGMGPACLQAK 377
YAAVN+++ Q ++ + R K R + +G N M P +
Sbjct: 362 YAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYM-PENGEKP 420
Query: 378 DGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWII 437
D + V+ S ++P +S ++ IDK SRI FP A+++FN+ YW I
Sbjct: 421 DRMMVQLTLASERSSPQRKSQRSSYVSMRI---DTHAIDKYSRIIFPAAYILFNLIYWSI 477
Query: 438 Y 438
+
Sbjct: 478 F 478
>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
[Homo sapiens]
Length = 453
Score = 272 bits (696), Expect = 4e-73
Identities = 161/416 (38%), Positives = 231/416 (55%), Gaps = 24/416 (5%)
Query: 39 SDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWND 98
S LD L+ GYD R+RP F G V +I++ SFG +++ M+Y +++F RQ W D
Sbjct: 33 SRILDNLL---EGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTD 89
Query: 99 PRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSI 158
RL + P + L L+ M+ IW PD FF N K + H +TT NKL RI +NG +LY++
Sbjct: 90 ERLKFGG-PTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTM 148
Query: 159 RITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF 215
R+T+ CPM L NFPMD C ++ S+ Y +++I+ W++ V + +L Q+
Sbjct: 149 RLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQY 208
Query: 216 ILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMD 275
L + K NTG++ + FHL+R+MGY++IQ+Y P ++ VILS +SFWIN +
Sbjct: 209 DLIGQTVSSETIKS-NTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
Query: 276 AAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV 335
+ PAR GITTVLTMTT S +R SLPKVSY A+D ++AVC FVFSAL+E+AAVN+
Sbjct: 268 SVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF 327
Query: 336 SRQHKELLRFRRKRRH--------HKEDEAGEGRFNF---SAYGMGPACLQAKDGISVKG 384
+ + + +RK + K E E S Y + I
Sbjct: 328 TNLQTQ--KAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSS 385
Query: 385 ANNSNTTNPPPAPSK--SPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
N T P S +P + F KID+ SRI FP+AF FN+ YW++Y
Sbjct: 386 EANKVLTRAPILQSTPVTPPPLSPAF-GGTSKIDQYSRILFPVAFAGFNLVYWVVY 440
>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
precursor [Homo sapiens]
Length = 462
Score = 272 bits (695), Expect = 5e-73
Identities = 154/413 (37%), Positives = 232/413 (56%), Gaps = 22/413 (5%)
Query: 45 LMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYN 104
L G GYD R+RP V +I++ SFG +++T M+Y +++F RQ W D RL +
Sbjct: 53 LDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFK 112
Query: 105 EYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTL 164
P L L+ + IW PD FF N K + H +TT NKLLR+ +G +LY++R+T++
Sbjct: 113 G-PMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISA 171
Query: 165 ACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQE---QGAVQVADGLTLPQFILKEEK 221
CPM L++FPMD C ++ S+ Y +++++ W + V DG L Q+ L +
Sbjct: 172 ECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
Query: 222 DLRYCTKHYNT--GKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPA 279
T++ +T G++T + A FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ PA
Sbjct: 232 ---VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 288
Query: 280 RVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ- 338
R G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++
Sbjct: 289 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 348
Query: 339 -----HKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNP 393
K L + K++ F P + + A SNTT+
Sbjct: 349 WAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQ-----TPAGTSNTTSV 403
Query: 394 PPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDV 446
PS+ K KIDK+SRI FP+ F FN+ YW Y + RE V
Sbjct: 404 SVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY--LNREPV 454
>gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor
[Homo sapiens]
Length = 492
Score = 271 bits (692), Expect = 1e-72
Identities = 159/419 (37%), Positives = 238/419 (56%), Gaps = 23/419 (5%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V +I++ SFG +++T M+Y +++F RQ W+D RL
Sbjct: 71 LDRLL---DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
++ P L L+ + IW PD FF N K + H +TT NKLLR+ NG +LY++R+T
Sbjct: 128 KFDG-PMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ--EQGAVQVA-DGLTLPQFILK 218
+ CPM L++FPMDV C ++ S+ YT ++++ W + +V+VA DG L Q+ L
Sbjct: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
Query: 219 EEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAP 278
+ +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++ P
Sbjct: 247 GHVVGTEIIRS-STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 305
Query: 279 ARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR- 337
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 306 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 365
Query: 338 ----QHKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKD---GISVKGANNSNT 390
+ K++ ++ A + F+ G AKD KGA S +
Sbjct: 366 SWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSAS 425
Query: 391 TNP-----PPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRRE 444
+ P P A K+DKISRI FP+ F IFN+ YW Y V RE
Sbjct: 426 STPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATY--VNRE 482
>gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 269 bits (688), Expect = 3e-72
Identities = 154/407 (37%), Positives = 233/407 (57%), Gaps = 20/407 (4%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217
+ CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 338 Q-----HKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTN 392
+ K ++ + K+ + + +A P + G++ S T
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKK-NNTYAPTATSYTPNLARGDPGLAT--IAKSATIE 396
Query: 393 PPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
P P P E +K F KID++SRI FP+ F IFN+ YW Y
Sbjct: 397 PKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 269 bits (688), Expect = 3e-72
Identities = 154/407 (37%), Positives = 233/407 (57%), Gaps = 20/407 (4%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217
+ CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 338 Q-----HKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTN 392
+ K ++ + K+ + + +A P + G++ S T
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKK-NNTYAPTATSYTPNLARGDPGLAT--IAKSATIE 396
Query: 393 PPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
P P P E +K F KID++SRI FP+ F IFN+ YW Y
Sbjct: 397 PKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 269 bits (688), Expect = 3e-72
Identities = 154/407 (37%), Positives = 233/407 (57%), Gaps = 20/407 (4%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217
+ CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 338 Q-----HKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTN 392
+ K ++ + K+ + + +A P + G++ S T
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKK-NNTYAPTATSYTPNLARGDPGLAT--IAKSATIE 396
Query: 393 PPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
P P P E +K F KID++SRI FP+ F IFN+ YW Y
Sbjct: 397 PKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 269 bits (688), Expect = 3e-72
Identities = 154/407 (37%), Positives = 233/407 (57%), Gaps = 20/407 (4%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217
+ CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 338 Q-----HKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTN 392
+ K ++ + K+ + + +A P + G++ S T
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKK-NNTYAPTATSYTPNLARGDPGLAT--IAKSATIE 396
Query: 393 PPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
P P P E +K F KID++SRI FP+ F IFN+ YW Y
Sbjct: 397 PKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 269 bits (688), Expect = 3e-72
Identities = 154/407 (37%), Positives = 233/407 (57%), Gaps = 20/407 (4%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217
+ CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 338 Q-----HKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTN 392
+ K ++ + K+ + + +A P + G++ S T
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKK-NNTYAPTATSYTPNLARGDPGLAT--IAKSATIE 396
Query: 393 PPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
P P P E +K F KID++SRI FP+ F IFN+ YW Y
Sbjct: 397 PKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 269 bits (688), Expect = 3e-72
Identities = 154/407 (37%), Positives = 233/407 (57%), Gaps = 20/407 (4%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217
+ CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 338 Q-----HKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTN 392
+ K ++ + K+ + + +A P + G++ S T
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKK-NNTYAPTATSYTPNLARGDPGLAT--IAKSATIE 396
Query: 393 PPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
P P P E +K F KID++SRI FP+ F IFN+ YW Y
Sbjct: 397 PKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 269 bits (688), Expect = 3e-72
Identities = 154/407 (37%), Positives = 233/407 (57%), Gaps = 20/407 (4%)
Query: 42 LDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRL 101
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 102 AYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRIT 161
+ P L L+ M IW PD FF N K + H +T NKLLRI+ +G +LY++R+T
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 162 LTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF-IL 217
+ CPM L++FPMD C ++ S+ YT ++++EW + A V DG L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 218 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAA 277
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS +SFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 278 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 337
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 338 Q-----HKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTN 392
+ K ++ + K+ + + +A P + G++ S T
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKK-NNTYAPTATSYTPNLARGDPGLAT--IAKSATIE 396
Query: 393 PPPA-PSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
P P P E +K F KID++SRI FP+ F IFN+ YW Y
Sbjct: 397 PKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2
precursor [Homo sapiens]
Length = 490
Score = 266 bits (680), Expect = 3e-71
Identities = 149/418 (35%), Positives = 232/418 (55%), Gaps = 40/418 (9%)
Query: 48 RTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYP 107
R +D +RP F GP + V ++ + S SI+E MD+ + ++LR W D RLA++
Sbjct: 85 RVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSAS 144
Query: 108 DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACP 167
+ S+ D ++ IW PD+FF + K + H+ TTDN +LR+ +G+VLYS+RIT+T C
Sbjct: 145 NKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCN 204
Query: 168 MDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQE-QGAVQVADGLTLPQFILKEEKDLRYC 226
MD +FP+D QTC ++LES+ YT DL+ W+ +++ + ++L QF++++
Sbjct: 205 MDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRL 264
Query: 227 TKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGIT 286
+ +TG + + F L R + ++L+Q Y P+ L+V+LSW+SFWI+ A PARV LGIT
Sbjct: 265 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 324
Query: 287 TVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFR 346
TVLTMTT +G AS+P+VSYVKA+DI++ V +FVF ++LEYAAVN+++ +
Sbjct: 325 TVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQE------ 378
Query: 347 RKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRK 406
RK R +E +F GM + DG + NS P E K
Sbjct: 379 RKERKLRE------KFPCMC-GMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDK 431
Query: 407 LFI--------------------------QRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
+ + Q IDK SR+ FP +++ FN+ YW ++
Sbjct: 432 IVVHLGLSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,298,052
Number of Sequences: 37866
Number of extensions: 767952
Number of successful extensions: 3186
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 2972
Number of HSP's gapped (non-prelim): 120
length of query: 449
length of database: 18,247,518
effective HSP length: 106
effective length of query: 343
effective length of database: 14,233,722
effective search space: 4882166646
effective search space used: 4882166646
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.