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Search of human proteins with 118498364
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|118498364 dapper 1 isoform 2 [Homo sapiens]
(799 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118498364 dapper 1 isoform 2 [Homo sapiens] 1601 0.0
gi|24158478 dapper 1 isoform 1 [Homo sapiens] 1583 0.0
gi|182507165 thymus expressed gene 3-like [Homo sapiens] 124 4e-28
gi|163965434 dapper, antagonist of beta-catenin, homolog 2 [Homo... 105 1e-22
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 53 1e-06
gi|189181750 human immunodeficiency virus type I enhancer bindin... 45 3e-04
gi|116089331 human immunodeficiency virus type I enhancer bindin... 45 3e-04
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 44 5e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 42 0.002
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 42 0.002
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 42 0.002
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 42 0.002
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 42 0.002
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 42 0.002
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 42 0.002
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 42 0.002
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 42 0.003
gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens] 41 0.004
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 41 0.004
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 41 0.005
gi|47132529 suppression of tumorigenicity 5 isoform 1 [Homo sapi... 41 0.005
gi|47132532 suppression of tumorigenicity 5 isoform 1 [Homo sapi... 41 0.005
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap... 40 0.007
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap... 40 0.007
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 40 0.007
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 39 0.019
gi|167234419 thyroid hormone receptor associated protein 3 [Homo... 39 0.019
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 39 0.019
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 39 0.019
gi|30795231 brain abundant, membrane attached signal protein 1 [... 39 0.025
>gi|118498364 dapper 1 isoform 2 [Homo sapiens]
Length = 799
Score = 1601 bits (4146), Expect = 0.0
Identities = 799/799 (100%), Positives = 799/799 (100%)
Query: 1 MKPSPAGTAKELEPPAPARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEY 60
MKPSPAGTAKELEPPAPARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEY
Sbjct: 1 MKPSPAGTAKELEPPAPARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEY 60
Query: 61 LRQRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRR 120
LRQRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRR
Sbjct: 61 LRQRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRR 120
Query: 121 RDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVF 180
RDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVF
Sbjct: 121 RDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVF 180
Query: 181 SECLSSCHSSTCFCSPLEATLSLSDGCPKSADVNPKYQCDLVSKNGNDVYRYPSPLHAVA 240
SECLSSCHSSTCFCSPLEATLSLSDGCPKSADVNPKYQCDLVSKNGNDVYRYPSPLHAVA
Sbjct: 181 SECLSSCHSSTCFCSPLEATLSLSDGCPKSADVNPKYQCDLVSKNGNDVYRYPSPLHAVA 240
Query: 241 VQSPMFLLCLTGNPLREEDRLGNHASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKK 300
VQSPMFLLCLTGNPLREEDRLGNHASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKK
Sbjct: 241 VQSPMFLLCLTGNPLREEDRLGNHASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKK 300
Query: 301 MDGYILSLVQKKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQ 360
MDGYILSLVQKKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQ
Sbjct: 301 MDGYILSLVQKKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQ 360
Query: 361 ACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAK 420
ACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAK
Sbjct: 361 ACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAK 420
Query: 421 PASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQG 480
PASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQG
Sbjct: 421 PASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQG 480
Query: 481 VPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMG 540
VPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMG
Sbjct: 481 VPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMG 540
Query: 541 VVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGG 600
VVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGG
Sbjct: 541 VVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGG 600
Query: 601 PEAGVPGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRG 660
PEAGVPGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRG
Sbjct: 601 PEAGVPGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRG 660
Query: 661 RRENVGLYPAPVPLPYASPYAYVASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDS 720
RRENVGLYPAPVPLPYASPYAYVASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDS
Sbjct: 661 RRENVGLYPAPVPLPYASPYAYVASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDS 720
Query: 721 ESSVSEGEFVGESTTTSDSEESGGLIWSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHN 780
ESSVSEGEFVGESTTTSDSEESGGLIWSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHN
Sbjct: 721 ESSVSEGEFVGESTTTSDSEESGGLIWSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHN 780
Query: 781 LKKKILRFRSGSLKLMTTV 799
LKKKILRFRSGSLKLMTTV
Sbjct: 781 LKKKILRFRSGSLKLMTTV 799
>gi|24158478 dapper 1 isoform 1 [Homo sapiens]
Length = 836
Score = 1583 bits (4098), Expect = 0.0
Identities = 799/836 (95%), Positives = 799/836 (95%), Gaps = 37/836 (4%)
Query: 1 MKPSPAGTAKELEPPAPARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEY 60
MKPSPAGTAKELEPPAPARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEY
Sbjct: 1 MKPSPAGTAKELEPPAPARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEY 60
Query: 61 LRQRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRR 120
LRQRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRR
Sbjct: 61 LRQRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRR 120
Query: 121 RDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVF 180
RDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVF
Sbjct: 121 RDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVF 180
Query: 181 SECLSSCHSSTCFCSPLEATLSLSDGCPKSAD---------------------------- 212
SECLSSCHSSTCFCSPLEATLSLSDGCPKSAD
Sbjct: 181 SECLSSCHSSTCFCSPLEATLSLSDGCPKSADLIGLLEYKEGHCEDQASGAVCRSLSTPQ 240
Query: 213 ---------VNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNPLREEDRLGN 263
VNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNPLREEDRLGN
Sbjct: 241 FNSLDVIADVNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNPLREEDRLGN 300
Query: 264 HASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRT 323
HASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRT
Sbjct: 301 HASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRT 360
Query: 324 SVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWS 383
SVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWS
Sbjct: 361 SVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWS 420
Query: 384 KESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQ 443
KESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQ
Sbjct: 421 KESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQ 480
Query: 444 LSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDF 503
LSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDF
Sbjct: 481 LSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDF 540
Query: 504 KSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLPT 563
KSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLPT
Sbjct: 541 KSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLPT 600
Query: 564 VREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGH 623
VREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGH
Sbjct: 601 VREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGH 660
Query: 624 GREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRGRRENVGLYPAPVPLPYASPYAYV 683
GREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRGRRENVGLYPAPVPLPYASPYAYV
Sbjct: 661 GREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRGRRENVGLYPAPVPLPYASPYAYV 720
Query: 684 ASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVSEGEFVGESTTTSDSEESG 743
ASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVSEGEFVGESTTTSDSEESG
Sbjct: 721 ASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVSEGEFVGESTTTSDSEESG 780
Query: 744 GLIWSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHNLKKKILRFRSGSLKLMTTV 799
GLIWSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHNLKKKILRFRSGSLKLMTTV
Sbjct: 781 GLIWSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHNLKKKILRFRSGSLKLMTTV 836
>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
Length = 629
Score = 124 bits (310), Expect = 4e-28
Identities = 164/579 (28%), Positives = 220/579 (37%), Gaps = 82/579 (14%)
Query: 261 LGNHASDIC---GGSELDAVKTDSSLPSPSSLWSASHPSSSKKMD-GYILSLVQKKTHPV 316
LG D+ GG E ++ ++ PSS P S+ D G+ S + P
Sbjct: 93 LGQQLGDLSLESGGLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGP- 151
Query: 317 RTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTF 376
++PR ++ K L G AP V G + S A P+ G G+
Sbjct: 152 --SEPRGIYASERPKSL---GDASPSAPEVV--GARAAVPRSFSAPYPTAG------GSA 198
Query: 377 SPPKQWSKESKAE----------QAESKRVPLPEGCP---------SGAASDLQSKHLPK 417
P S E +A A + R P P G P +G D L +
Sbjct: 199 GPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLR 258
Query: 418 TAKPASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLKKMSQKNS 477
+ R S G P+ + P SPS G A P ++ +
Sbjct: 259 RRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERV-------- 310
Query: 478 LQGVPPATPPLLSTAFP------VEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVR 531
G P +P LS A+ PA + S E LVKAQ+IPG Q + R
Sbjct: 311 --GGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATR 368
Query: 532 LHRGHRNMGVVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDT--NKKLKK 589
G+ ++ + P +G RE+ RA ++ R + + + +K
Sbjct: 369 --------GLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARK 420
Query: 590 AS-SKGRKSGGGPEAGVPGRPAG--GGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSA 646
AS S+ S G + VP P R R R RRW+S+A
Sbjct: 421 ASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTA 480
Query: 647 EISYEEALRRARRGRRENVGLYPAPVPLPYASP----YAYVASDSEYSAECESLFHSTVV 702
EI + R R V P P P P A Y SDSE SA +
Sbjct: 481 EIDAADGRRVRPRAPAARV---PGPGPSPSAPQRRLLYGCAGSDSECSA-------GRLG 530
Query: 703 DTSEDEQSNYTTNCFGDSESSVSEGEFVGESTTTSDSEESGGLIWSQ--FVQTLPIQTVT 760
+ +G+SESS SEGE S+ +SDS+ SGGL+W Q T
Sbjct: 531 PLGRRGPAGGVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGA 590
Query: 761 APDLHNHPAKTFVKIKASHNLKKKILRFRSGSLKLMTTV 799
PAK FVKIKASH LKKKILRFRSGSLK+MTTV
Sbjct: 591 GAGAPAGPAKVFVKIKASHALKKKILRFRSGSLKVMTTV 629
Score = 60.1 bits (144), Expect = 8e-09
Identities = 121/509 (23%), Positives = 175/509 (34%), Gaps = 115/509 (22%)
Query: 40 ERQRTRERQEATLAGLAELEYLRQRQELLVRGALR----GAGGAGAAAPRAGELLGEAAQ 95
ER R R E +LAGL EL +LR+RQE V+ ALR G GGA EA
Sbjct: 12 ERGRLRGWLEGSLAGLCELHWLRERQEYRVQQALRLAQPGMGGA------------EAED 59
Query: 96 RSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDS 155
+E +E+ R+ L + L + +L +Q+ DL L+ LE +S
Sbjct: 60 EEDADE---DEDAAAARRAAAALEEQLEALPGLVWDLGQQLGDLSLE-----SGGLEQES 111
Query: 156 RPSSGFYELSDGASGSLSNSSNSVFSECLSSCHSSTCFCSPL-----------EATLSLS 204
SSGFYE D +S +S S F C S S + L E SL
Sbjct: 112 GRSSGFYE--DPSSTGGPDSPPSTF--CGDSGFSGSSSYGRLGPSEPRGIYASERPKSLG 167
Query: 205 DGCPKSADV----------------------NPKYQCDLVSKNGNDVYRYPSPLHAVAVQ 242
D P + +V P+ + + PSPLHAVA++
Sbjct: 168 DASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMR 227
Query: 243 SPMFLLCLTGNPLREEDRLGNHASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMD 302
SP CG D S + + +D
Sbjct: 228 SPR----------------------PCGRPPTD---------------SPDAGGAGRPLD 250
Query: 303 GYILSLVQKKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQAC 362
GYI +L++++ +PRTS G R SV R P S + +++
Sbjct: 251 GYISALLRRRRRR-GAGQPRTSPGG-ADGGPRRQNSVRQRPPDASPSPGSA--RPAREPS 306
Query: 363 LPSGGIPSLNNGTFSP--PKQWSKESKAEQAESKRVPLPEGCPSGA----ASDLQSKHLP 416
L G + S W E+ E A P P P+ A +
Sbjct: 307 LERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAA 366
Query: 417 KTAKPASQEHARCSAIGTGES-----PKESAQLSGASPKESPSRG-PAPPQENKVVQPLK 470
P + + G S P+E + +G + + + G P+ K +
Sbjct: 367 TRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQS 426
Query: 471 KMSQKNSLQGVPPATPPLLSTAFPVEERP 499
+ S V P+ PP TA E RP
Sbjct: 427 ETSLLGRASAV-PSGPPKYPTAEREEPRP 454
>gi|163965434 dapper, antagonist of beta-catenin, homolog 2 [Homo
sapiens]
Length = 774
Score = 105 bits (263), Expect = 1e-22
Identities = 77/179 (43%), Positives = 98/179 (54%), Gaps = 8/179 (4%)
Query: 35 GEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGAAAPRAGELLGEAA 94
G A +R+R R A AGL EL+ LR Q+ VRGAL AAP L
Sbjct: 9 GSAGWDRRRLGARLRAAFAGLQELQGLRATQQERVRGALALQPPPAPAAPCGPHGLHGPE 68
Query: 95 QRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETD 154
Q+ LE + L++QL+ LR++D GL L +LD QIS L+LDV S E L++D
Sbjct: 69 QQ-------LEAALAALQEQLSRLRQQDIGLKTHLDQLDLQISKLQLDVGTASGEALDSD 121
Query: 155 SRPSSGFYELSDGASGSLSNSSNSVFSECLS-SCHSSTCFCSPLEATLSLSDGCPKSAD 212
SRPSSGFYE+SDG S SLS S SV S+ +S S S +A S+ D P+S D
Sbjct: 122 SRPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVD 180
Score = 95.1 bits (235), Expect = 2e-19
Identities = 155/617 (25%), Positives = 229/617 (37%), Gaps = 130/617 (21%)
Query: 214 NPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLC----LTGNPL--REEDRLGNHASD 267
+PKY+ DLVS+ G +VY YPSPLHAVA+QSP+F+L G P RE R +
Sbjct: 257 DPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGGPSFPRESPRGPAGLNT 316
Query: 268 ICGGSELDA--VKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRTSV 325
I G L+A + + + LW P+ + + Q + P+
Sbjct: 317 IQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGE-------QGPLRHAASPSPQRQG 369
Query: 326 NADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLN--NGTFSPPKQWS 383
G G + V APG +G + + + G L + S P++ S
Sbjct: 370 GWSTDGG----GRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSLPEEGS 425
Query: 384 KESKA---------EQAESKRVPLPEGCPSGAASDLQ-SKHLPKTAKPASQEHARCSAIG 433
K S + SK P G + + S+ L K+ PAS A
Sbjct: 426 KPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGHFAH----- 480
Query: 434 TGESPKESAQLSGASPK---ESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLS 490
P +A L PK E R P QPL + + P +
Sbjct: 481 ----PSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDP 536
Query: 491 TAFP-----VEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNS 545
+P ++ RPAL +++ G S S E +P + V
Sbjct: 537 AHWPTGRGGLQRRPALAWEAPGRSCS-ESTLYPMPVLVP--------------LAVAPQE 581
Query: 546 SLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGV 605
S + AL E L T + A K R+ ++ + + + AS PE+ +
Sbjct: 582 SHRTSAQALFPFEASLLT----SVARRKHRRWQSTVEISARARLASC--------PESNL 629
Query: 606 PGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRGRRENV 665
G P RAG GR ++V + + R+D K SA
Sbjct: 630 -GPPRPVARRAGGPL-ARGRPSLVRQDAYTRSDSEPSKHSA------------------- 668
Query: 666 GLYPAPVPLPYASPYAYVASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVS 725
EC+ F S + +TSE E S++TTN FGD ESS S
Sbjct: 669 --------------------------ECDPRFPSVIPETSEGESSDHTTNRFGDRESSSS 702
Query: 726 EGEFVGESTTTSDSEESGGLI---WSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHNLK 782
+ E +S D + + G + ++ T + P L P +IKAS LK
Sbjct: 703 DEEGGAQS---RDCDLALGYVAAGHAELAWTQEAPVSSGPLL--SPVPKLCRIKASKALK 757
Query: 783 KKILRFRSGSLKLMTTV 799
KKI RF+ +LK+MT V
Sbjct: 758 KKIRRFQPTALKVMTMV 774
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 52.8 bits (125), Expect = 1e-06
Identities = 83/353 (23%), Positives = 136/353 (38%), Gaps = 47/353 (13%)
Query: 342 RAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEG 401
R+ G SQ V S Q S P T +P +Q S+ + + +SK P
Sbjct: 1536 RSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRR 1595
Query: 402 CPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPKESPS------R 455
SG++ +++ K P+ A A G+ SP+ A A P+ S S R
Sbjct: 1596 SRSGSSPEVKDK--PRAAPRAQS--------GSDSSPEPKAPAPRALPRRSRSGSSSKGR 1645
Query: 456 GPAP----PQENKVVQPLKKMSQKNSLQGVP-----PATPP--LLSTAFPVEERPA-LDF 503
GP+P E+ P K + + + P TPP S + P R A L
Sbjct: 1646 GPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSR 1705
Query: 504 KSEGSSQSLEEAHLV-----KAQFIPGQQPS--VRLHRGHRNMGVVKNSSLKHRG----P 552
+S +S S E ++ + +P+ R R R+ + + RG P
Sbjct: 1706 RSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSP 1765
Query: 553 ALQGLENGLP-TVREKTRAGSKKCRFPDDLDTNKKLKKASSKG-----RKSGGGPEAGVP 606
+GL+ + REKTR ++ R T+++ +++ S+ R+ G G + P
Sbjct: 1766 KPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSP 1825
Query: 607 GRPAGGGHRAGSRAHGHGREAVVAKPKHK-RTDYRRWKSSAEISYEEALRRAR 658
R + R G R ++ + + RT WK S + RR+R
Sbjct: 1826 ARQE-SSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSR 1877
Score = 44.7 bits (104), Expect = 3e-04
Identities = 123/573 (21%), Positives = 194/573 (33%), Gaps = 76/573 (13%)
Query: 4 SPAGTAKELEPPAPARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQ 63
SP PA G R+ P R R + R R+R R A +G + +
Sbjct: 629 SPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPAR 688
Query: 64 RQELLVRGALRG---------AGGAGAAAPRAGELLGEAAQR---SRLEEKFLEENILLL 111
R R RG G + + P+ G +++R SR ++ N
Sbjct: 689 RGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPE 748
Query: 112 RKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTS---EEHLETDSRPSSGFYELSDGA 168
K+ RR L + + ++S LR + +S ++ +T R S S +
Sbjct: 749 MKKSRISSRRSRSLSSPRSKAKSRLS-LRRSLSGSSPCPKQKSQTPPRRSR-----SGSS 802
Query: 169 SGSLSNSSNSVFSECLSSCHSSTCFCSPLEATLSLSDGCPKSADVNPKYQCDLVSKNGND 228
+ + S SS +P + S S PK P Q + S N+
Sbjct: 803 QPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANE 862
Query: 229 VYRYP--------SPLHAVAVQSPMFLLCLTGNPLREEDRLGNHASDICGGSELDAVK-- 278
P SP + ++P C +P R + S S VK
Sbjct: 863 QSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAI 922
Query: 279 --------TDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRTSVNADPT 330
+ SS PSPS + S + P S+ + S V+ + P ++ +S +
Sbjct: 923 ISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSP--CSNVESRLLPRYSHSGSSSPDT--- 977
Query: 331 KGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQ 390
V P S S++ +A P G PSL+ P++ SK+S +
Sbjct: 978 -------KVKPETPPRQSHSGSISPYPKVKAQTPPG--PSLSGSKSPCPQEKSKDSLVQS 1028
Query: 391 AESK-------RVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQ 443
+ P G S LQ K +T+ P + + S S Q
Sbjct: 1029 CPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTS-PDHRSDTSSPEVRQSHSESPSLQ 1087
Query: 444 -LSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEER---- 498
S SPK SR +P E P+++ +G A+P L S P + R
Sbjct: 1088 SKSQTSPKGGRSRSSSPVTELASRSPIRQD------RGEFSASPMLKSGMSPEQSRFQSD 1141
Query: 499 ----PALDFKSEGSSQSLEEAHLVKAQFIPGQQ 527
P +D S LE A + +P Q+
Sbjct: 1142 SSSYPTVDSNSLLGQSRLETAESKEKMALPPQE 1174
Score = 44.7 bits (104), Expect = 3e-04
Identities = 68/312 (21%), Positives = 112/312 (35%), Gaps = 54/312 (17%)
Query: 369 PSLNNGTFSPPKQWS-KESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHA 427
P LNN +P ++ S ES +Q R PL + SG++ +L KP++
Sbjct: 1503 PELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELD-------VKPSASPQE 1555
Query: 428 RCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPP 487
R + + +S ++ +P SR + P+ V ++S + S G P
Sbjct: 1556 RSESDSSPDSKAKT-----RTPLRQRSRSGSSPE----VDSKSRLSPRRSRSGSSP---- 1602
Query: 488 LLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSL 547
V+++P +++ S S E + +P + S SS
Sbjct: 1603 ------EVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRS--------------GSSS 1642
Query: 548 KHRGPALQGLEN--GLPTVREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGV 605
K RGP+ +G + P K+R + R + T + + R S PE
Sbjct: 1643 KGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTK---SRTPPRRRSSRSSPELTR 1699
Query: 606 PGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRGRRENV 665
R + A S R P+H+R+ AE S RR+ R
Sbjct: 1700 KARLSRRSRSASSSPETRSR----TPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKT 1755
Query: 666 ----GLYPAPVP 673
G P+P P
Sbjct: 1756 TSRRGRSPSPKP 1767
Score = 32.7 bits (73), Expect = 1.4
Identities = 41/182 (22%), Positives = 67/182 (36%), Gaps = 8/182 (4%)
Query: 351 NSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDL 410
+S + +S + S S ++G+ S + S + KRVP P P A +
Sbjct: 2534 SSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREG 2593
Query: 411 QSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLK 470
+ P PA ++ R S+ + S S+ S +S S S + +
Sbjct: 2594 R----PPEPTPAKRKR-RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
Query: 471 KMSQKNSLQGVP-PATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPS 529
K Q +P PA+P P S S+SL + + + + P QPS
Sbjct: 2649 PSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRR--PSPQPS 2706
Query: 530 VR 531
R
Sbjct: 2707 PR 2708
Score = 32.0 bits (71), Expect = 2.3
Identities = 65/305 (21%), Positives = 105/305 (34%), Gaps = 31/305 (10%)
Query: 380 KQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHAR----CSAIGTG 435
K+ SK+ K +++ S P P+ + ++ S T++ S+ A + G
Sbjct: 237 KRKSKDKKRKRSRST-TPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRS 295
Query: 436 ESPKESAQLSGASPKESP----SRGPAPPQENKVVQPL-----KKMSQKNSLQGVPPATP 486
SP + G +P P ++ P+ P E QP K +K P +P
Sbjct: 296 PSPASGRRGEGDAPFSEPGTTSTQRPSSP-ETATKQPSSPYEDKDKDKKEKSATRPSPSP 354
Query: 487 PLLSTA-FPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMG--VVK 543
ST P P L + GS Q L L + P + S R + +
Sbjct: 355 ERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQ 414
Query: 544 NSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLD------TNKKLKKASSKGRKS 597
+SS + P+ Q PT + + S + P ++ K S GR
Sbjct: 415 SSSSESSPPSPQ------PTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAK 468
Query: 598 GGGPEAGVPGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEIS-YEEALRR 656
+ P R G + G R K H R+ +W+ S + +
Sbjct: 469 RDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSP 528
Query: 657 ARRGR 661
RRGR
Sbjct: 529 QRRGR 533
Score = 31.6 bits (70), Expect = 3.0
Identities = 32/131 (24%), Positives = 45/131 (34%), Gaps = 9/131 (6%)
Query: 534 RGHRNMGVVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDTNKKLKKASSK 593
R R V+ S + R PA + +G R R G + R P ++ A
Sbjct: 623 RRSRTRSPVRRRS-RSRSPARR---SGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRS 678
Query: 594 GRKSGGGPEAGVPGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISYEEA 653
GR + P R R R R V H RT RR +S + +
Sbjct: 679 GRS-----RSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNK 733
Query: 654 LRRARRGRREN 664
R ++R R N
Sbjct: 734 SRTSQRRSRSN 744
>gi|189181750 human immunodeficiency virus type I enhancer binding
protein 3 b [Homo sapiens]
Length = 2405
Score = 44.7 bits (104), Expect = 3e-04
Identities = 117/580 (20%), Positives = 203/580 (35%), Gaps = 70/580 (12%)
Query: 151 LETDSRPSSGFYELSDGASGS--LSNSSNSVFSECLSSCHSSTCFCSPLEATLSLSDGCP 208
+ T P G Y D + S LS+SS+ VF+ PL S + P
Sbjct: 550 ISTPHHPFRGSYSFDDHITDSEALSHSSH-VFTSHPRMLKRQPAIELPLGGEYSSEEPGP 608
Query: 209 KSADVNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNPLREEDRLGNHASDI 268
S D K ++ K + L V ++ + G ++ D H
Sbjct: 609 SSKDTASKPSDEVEPKESELTKKTKKGLKTKGV---IYECNICGARYKKRDNYEAHKKYY 665
Query: 269 CGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRTSVNAD 328
C ++ + + SP + S +M Y L + T P+R + S+ +
Sbjct: 666 CSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELT-PLRKRRKEKSLGDE 724
Query: 329 PTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGT-FSP----PKQWS 383
+ +PG ++ L+++K PS +PSL T F P P S
Sbjct: 725 EEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGS 784
Query: 384 KESKAEQAESKRVPLPEGCPSGAASDL---------QSKHLPKTAKPASQEHARCS-AIG 433
+ K + SK + + + S SD + K L + P H R + ++
Sbjct: 785 ESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQ 844
Query: 434 TGESPKESAQLSGASPKESPSRGPA----PPQENKVVQPLKKMSQKNSLQGVPPATPPLL 489
+ + Q+ E P R PP+E + + + + +L +P P
Sbjct: 845 PKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLP-- 902
Query: 490 STAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKH 549
P ++R L ++ S +S E+ V P Q+ +V L R+ ++ K
Sbjct: 903 ----PKKKRLRLAEMAQSSGESSFESS-VPLSRSPSQESNVSLSGSSRSASFERDDHGKA 957
Query: 550 RGPA-------------LQGLENGLPTVREKTRAGSKKC-RFPDDLDTNKKLKKASSKGR 595
P+ + + + P RE R+ S++ + K+ G
Sbjct: 958 EAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGS 1017
Query: 596 KSGGGPEAGVPGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISYEEALR 655
S GP A P P A VA P+ ++ R ++S E L
Sbjct: 1018 LSLTGPSAPAPVAP----------------PARVAPPERRKCFLVR-QASLSRPPESELE 1060
Query: 656 RARRGRRENVGLYPAPVPLPYASPYAYVASDSEYSAECES 695
A +GR+E + P P +S + +S S+ S+ S
Sbjct: 1061 VAPKGRQE------SEEPQPSSSKPSAKSSLSQISSAATS 1094
>gi|116089331 human immunodeficiency virus type I enhancer binding
protein 3 [Homo sapiens]
Length = 2406
Score = 44.7 bits (104), Expect = 3e-04
Identities = 117/580 (20%), Positives = 203/580 (35%), Gaps = 70/580 (12%)
Query: 151 LETDSRPSSGFYELSDGASGS--LSNSSNSVFSECLSSCHSSTCFCSPLEATLSLSDGCP 208
+ T P G Y D + S LS+SS+ VF+ PL S + P
Sbjct: 550 ISTPHHPFRGSYSFDDHITDSEALSHSSH-VFTSHPRMLKRQPAIELPLGGEYSSEEPGP 608
Query: 209 KSADVNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNPLREEDRLGNHASDI 268
S D K ++ K + L V ++ + G ++ D H
Sbjct: 609 SSKDTASKPSDEVEPKESELTKKTKKGLKTKGV---IYECNICGARYKKRDNYEAHKKYY 665
Query: 269 CGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRTSVNAD 328
C ++ + + SP + S +M Y L + T P+R + S+ +
Sbjct: 666 CSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELT-PLRKRRKEKSLGDE 724
Query: 329 PTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGT-FSP----PKQWS 383
+ +PG ++ L+++K PS +PSL T F P P S
Sbjct: 725 EEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGS 784
Query: 384 KESKAEQAESKRVPLPEGCPSGAASDL---------QSKHLPKTAKPASQEHARCS-AIG 433
+ K + SK + + + S SD + K L + P H R + ++
Sbjct: 785 ESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQ 844
Query: 434 TGESPKESAQLSGASPKESPSRGPA----PPQENKVVQPLKKMSQKNSLQGVPPATPPLL 489
+ + Q+ E P R PP+E + + + + +L +P P
Sbjct: 845 PKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLP-- 902
Query: 490 STAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKH 549
P ++R L ++ S +S E+ V P Q+ +V L R+ ++ K
Sbjct: 903 ----PKKKRLRLAEMAQSSGESSFESS-VPLSRSPSQESNVSLSGSSRSASFERDDHGKA 957
Query: 550 RGPA-------------LQGLENGLPTVREKTRAGSKKC-RFPDDLDTNKKLKKASSKGR 595
P+ + + + P RE R+ S++ + K+ G
Sbjct: 958 EAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGS 1017
Query: 596 KSGGGPEAGVPGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISYEEALR 655
S GP A P P A VA P+ ++ R ++S E L
Sbjct: 1018 LSLTGPSAPAPVAP----------------PARVAPPERRKCFLVR-QASLSRPPESELE 1060
Query: 656 RARRGRRENVGLYPAPVPLPYASPYAYVASDSEYSAECES 695
A +GR+E + P P +S + +S S+ S+ S
Sbjct: 1061 VAPKGRQE------SEEPQPSSSKPSAKSSLSQISSAATS 1094
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 44.3 bits (103), Expect = 5e-04
Identities = 86/358 (24%), Positives = 127/358 (35%), Gaps = 43/358 (12%)
Query: 278 KTDSSLPSPSSLWSASHPSSSKKMD-----GYILSLVQKKTH--PVRTNKPRTSVNADPT 330
KTD +P+ + L PS S + + ++++ TH P T A+P+
Sbjct: 324 KTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPS 383
Query: 331 KGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQ 390
K P SQ S +N KQ S + GT S + + S +E
Sbjct: 384 K---------FPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSED 434
Query: 391 AESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPK 450
++S++ P E PS +A + LP+ A A + +S +S S +S
Sbjct: 435 SDSEQTP--EKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDS 492
Query: 451 ES--PSRGPAPPQENKVVQPLKKMSQKNSLQGV-PPATPPLLSTAFPVEERPALDFKSEG 507
E P PAP E K N L V PA PP + E P +S+G
Sbjct: 493 EENEPLETPAPEPEPPTT---NKWQLDNWLTKVSQPAAPPEGPRS---TEPPRRHPESKG 546
Query: 508 SSQSLEEAHLVKAQFIP----GQQPSVRLHRGHRNMGVVKNSSLKHRGPALQ--GLENGL 561
SS S +++ P + P H + S + P Q G +
Sbjct: 547 SSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPK 606
Query: 562 PTVREKTRAGSKKC----RFPDDL------DTNKKLKKASSKGRKSGGGPEAGVPGRP 609
V+ RAGS+ R P L T+K K +KGR P P
Sbjct: 607 KPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVP 664
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 25 AEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQR---QELLVRGALRGAGGAGA 81
AE + + +A+ E+Q+ +EA G AE + +RQR ++ L + G A
Sbjct: 1648 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1707
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
EL+ R R E + E+ LL ++L L+R A + QEL+ +++ +R
Sbjct: 1708 RLAAEQELI-----RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1762
Query: 142 DVE--KTSEEHLETDSRPSS 159
++E S+ E +SR +S
Sbjct: 1763 EMEVLLASKARAEEESRSTS 1782
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAG 80
E++ E + K +A+ E + ++R + + E Q+Q+ ++ L+ +
Sbjct: 1370 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1429
Query: 81 AAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLR 140
A +A EAA+RSRL +EE I ++R QL R+ G +LQ L + +
Sbjct: 1430 EAEIQAKARQAEAAERSRLR---IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE 1486
Query: 141 LDVEKTSEE 149
+ EE
Sbjct: 1487 AQKRQAQEE 1495
Score = 33.9 bits (76), Expect = 0.61
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 39/175 (22%)
Query: 18 ARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQ------------ 65
AR E+ + + +++ EA+ R R + A L LAE E RQRQ
Sbjct: 1772 ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE-EAKRQRQLAEEDAARQRAE 1830
Query: 66 -ELLVRGALRGAGGAGAAAPRAGELL---------------GEAAQRSRLEEKF------ 103
E ++ L G A A L EA QR RLEE+
Sbjct: 1831 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1890
Query: 104 LEENILLLRKQLNCLRRRDAGL----LNQLQELDKQISDLRLDVEKTSEEHLETD 154
+EE + LRK + R GL L Q ++++++I L+ EK + E +
Sbjct: 1891 IEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE 1945
Score = 33.1 bits (74), Expect = 1.0
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 22 QRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGA 81
+++AE + + R + +A E+ R QEA AE LRQ+Q
Sbjct: 2118 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2177
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
+A R +LEE ++N LL ++L L+ Q ++++++ +R+
Sbjct: 2178 LRQKAQVEQELTTLRLQLEETDHQKN--LLDEELQRLKAEATEAARQRSQVEEELFSVRV 2235
Query: 142 DVEKTS--EEHLETDSR 156
+E+ S + +E ++R
Sbjct: 2236 QMEELSKLKARIEAENR 2252
Score = 31.2 bits (69), Expect = 4.0
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 34 KGEADTERQRTRERQEATLAGLAELEYLRQRQELLVR-------GALRGAGGAGAAAPRA 86
+GEA+ R+ E +EA + E R++ E R A A AA
Sbjct: 2080 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2139
Query: 87 GELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKT 146
E EAA+R++ E+ L + ++ ++ L Q +++++++ LRL +E+T
Sbjct: 2140 KEAEQEAARRAQAEQAALRQK-QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2198
Query: 147 SEE 149
+
Sbjct: 2199 DHQ 2201
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 25 AEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQR---QELLVRGALRGAGGAGA 81
AE + + +A+ E+Q+ +EA G AE + +RQR ++ L + G A
Sbjct: 1652 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1711
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
EL+ R R E + E+ LL ++L L+R A + QEL+ +++ +R
Sbjct: 1712 RLAAEQELI-----RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1766
Query: 142 DVE--KTSEEHLETDSRPSS 159
++E S+ E +SR +S
Sbjct: 1767 EMEVLLASKARAEEESRSTS 1786
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAG 80
E++ E + K +A+ E + ++R + + E Q+Q+ ++ L+ +
Sbjct: 1374 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1433
Query: 81 AAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLR 140
A +A EAA+RSRL +EE I ++R QL R+ G +LQ L + +
Sbjct: 1434 EAEIQAKARQAEAAERSRLR---IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE 1490
Query: 141 LDVEKTSEE 149
+ EE
Sbjct: 1491 AQKRQAQEE 1499
Score = 33.9 bits (76), Expect = 0.61
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 39/175 (22%)
Query: 18 ARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQ------------ 65
AR E+ + + +++ EA+ R R + A L LAE E RQRQ
Sbjct: 1776 ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE-EAKRQRQLAEEDAARQRAE 1834
Query: 66 -ELLVRGALRGAGGAGAAAPRAGELL---------------GEAAQRSRLEEKF------ 103
E ++ L G A A L EA QR RLEE+
Sbjct: 1835 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1894
Query: 104 LEENILLLRKQLNCLRRRDAGL----LNQLQELDKQISDLRLDVEKTSEEHLETD 154
+EE + LRK + R GL L Q ++++++I L+ EK + E +
Sbjct: 1895 IEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE 1949
Score = 33.1 bits (74), Expect = 1.0
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 22 QRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGA 81
+++AE + + R + +A E+ R QEA AE LRQ+Q
Sbjct: 2122 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2181
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
+A R +LEE ++N LL ++L L+ Q ++++++ +R+
Sbjct: 2182 LRQKAQVEQELTTLRLQLEETDHQKN--LLDEELQRLKAEATEAARQRSQVEEELFSVRV 2239
Query: 142 DVEKTS--EEHLETDSR 156
+E+ S + +E ++R
Sbjct: 2240 QMEELSKLKARIEAENR 2256
Score = 31.2 bits (69), Expect = 4.0
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 34 KGEADTERQRTRERQEATLAGLAELEYLRQRQELLVR-------GALRGAGGAGAAAPRA 86
+GEA+ R+ E +EA + E R++ E R A A AA
Sbjct: 2084 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2143
Query: 87 GELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKT 146
E EAA+R++ E+ L + ++ ++ L Q +++++++ LRL +E+T
Sbjct: 2144 KEAEQEAARRAQAEQAALRQK-QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2202
Query: 147 SEE 149
+
Sbjct: 2203 DHQ 2205
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 25 AEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQR---QELLVRGALRGAGGAGA 81
AE + + +A+ E+Q+ +EA G AE + +RQR ++ L + G A
Sbjct: 1648 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1707
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
EL+ R R E + E+ LL ++L L+R A + QEL+ +++ +R
Sbjct: 1708 RLAAEQELI-----RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1762
Query: 142 DVE--KTSEEHLETDSRPSS 159
++E S+ E +SR +S
Sbjct: 1763 EMEVLLASKARAEEESRSTS 1782
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAG 80
E++ E + K +A+ E + ++R + + E Q+Q+ ++ L+ +
Sbjct: 1370 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1429
Query: 81 AAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLR 140
A +A EAA+RSRL +EE I ++R QL R+ G +LQ L + +
Sbjct: 1430 EAEIQAKARQAEAAERSRLR---IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE 1486
Query: 141 LDVEKTSEE 149
+ EE
Sbjct: 1487 AQKRQAQEE 1495
Score = 33.9 bits (76), Expect = 0.61
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 39/175 (22%)
Query: 18 ARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQ------------ 65
AR E+ + + +++ EA+ R R + A L LAE E RQRQ
Sbjct: 1772 ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE-EAKRQRQLAEEDAARQRAE 1830
Query: 66 -ELLVRGALRGAGGAGAAAPRAGELL---------------GEAAQRSRLEEKF------ 103
E ++ L G A A L EA QR RLEE+
Sbjct: 1831 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1890
Query: 104 LEENILLLRKQLNCLRRRDAGL----LNQLQELDKQISDLRLDVEKTSEEHLETD 154
+EE + LRK + R GL L Q ++++++I L+ EK + E +
Sbjct: 1891 IEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE 1945
Score = 33.1 bits (74), Expect = 1.0
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 22 QRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGA 81
+++AE + + R + +A E+ R QEA AE LRQ+Q
Sbjct: 2118 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2177
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
+A R +LEE ++N LL ++L L+ Q ++++++ +R+
Sbjct: 2178 LRQKAQVEQELTTLRLQLEETDHQKN--LLDEELQRLKAEATEAARQRSQVEEELFSVRV 2235
Query: 142 DVEKTS--EEHLETDSR 156
+E+ S + +E ++R
Sbjct: 2236 QMEELSKLKARIEAENR 2252
Score = 31.2 bits (69), Expect = 4.0
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 34 KGEADTERQRTRERQEATLAGLAELEYLRQRQELLVR-------GALRGAGGAGAAAPRA 86
+GEA+ R+ E +EA + E R++ E R A A AA
Sbjct: 2080 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2139
Query: 87 GELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKT 146
E EAA+R++ E+ L + ++ ++ L Q +++++++ LRL +E+T
Sbjct: 2140 KEAEQEAARRAQAEQAALRQK-QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2198
Query: 147 SEE 149
+
Sbjct: 2199 DHQ 2201
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 25 AEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQR---QELLVRGALRGAGGAGA 81
AE + + +A+ E+Q+ +EA G AE + +RQR ++ L + G A
Sbjct: 1616 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1675
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
EL+ R R E + E+ LL ++L L+R A + QEL+ +++ +R
Sbjct: 1676 RLAAEQELI-----RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1730
Query: 142 DVE--KTSEEHLETDSRPSS 159
++E S+ E +SR +S
Sbjct: 1731 EMEVLLASKARAEEESRSTS 1750
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAG 80
E++ E + K +A+ E + ++R + + E Q+Q+ ++ L+ +
Sbjct: 1338 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1397
Query: 81 AAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLR 140
A +A EAA+RSRL +EE I ++R QL R+ G +LQ L + +
Sbjct: 1398 EAEIQAKARQAEAAERSRLR---IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE 1454
Query: 141 LDVEKTSEE 149
+ EE
Sbjct: 1455 AQKRQAQEE 1463
Score = 33.9 bits (76), Expect = 0.61
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 39/175 (22%)
Query: 18 ARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQ------------ 65
AR E+ + + +++ EA+ R R + A L LAE E RQRQ
Sbjct: 1740 ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE-EAKRQRQLAEEDAARQRAE 1798
Query: 66 -ELLVRGALRGAGGAGAAAPRAGELL---------------GEAAQRSRLEEKF------ 103
E ++ L G A A L EA QR RLEE+
Sbjct: 1799 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1858
Query: 104 LEENILLLRKQLNCLRRRDAGL----LNQLQELDKQISDLRLDVEKTSEEHLETD 154
+EE + LRK + R GL L Q ++++++I L+ EK + E +
Sbjct: 1859 IEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE 1913
Score = 33.1 bits (74), Expect = 1.0
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 22 QRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGA 81
+++AE + + R + +A E+ R QEA AE LRQ+Q
Sbjct: 2086 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2145
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
+A R +LEE ++N LL ++L L+ Q ++++++ +R+
Sbjct: 2146 LRQKAQVEQELTTLRLQLEETDHQKN--LLDEELQRLKAEATEAARQRSQVEEELFSVRV 2203
Query: 142 DVEKTS--EEHLETDSR 156
+E+ S + +E ++R
Sbjct: 2204 QMEELSKLKARIEAENR 2220
Score = 31.2 bits (69), Expect = 4.0
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 34 KGEADTERQRTRERQEATLAGLAELEYLRQRQELLVR-------GALRGAGGAGAAAPRA 86
+GEA+ R+ E +EA + E R++ E R A A AA
Sbjct: 2048 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2107
Query: 87 GELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKT 146
E EAA+R++ E+ L + ++ ++ L Q +++++++ LRL +E+T
Sbjct: 2108 KEAEQEAARRAQAEQAALRQK-QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2166
Query: 147 SEE 149
+
Sbjct: 2167 DHQ 2169
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 25 AEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQR---QELLVRGALRGAGGAGA 81
AE + + +A+ E+Q+ +EA G AE + +RQR ++ L + G A
Sbjct: 1785 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1844
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
EL+ R R E + E+ LL ++L L+R A + QEL+ +++ +R
Sbjct: 1845 RLAAEQELI-----RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1899
Query: 142 DVE--KTSEEHLETDSRPSS 159
++E S+ E +SR +S
Sbjct: 1900 EMEVLLASKARAEEESRSTS 1919
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAG 80
E++ E + K +A+ E + ++R + + E Q+Q+ ++ L+ +
Sbjct: 1507 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1566
Query: 81 AAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLR 140
A +A EAA+RSRL +EE I ++R QL R+ G +LQ L + +
Sbjct: 1567 EAEIQAKARQAEAAERSRLR---IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE 1623
Query: 141 LDVEKTSEE 149
+ EE
Sbjct: 1624 AQKRQAQEE 1632
Score = 33.9 bits (76), Expect = 0.61
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 39/175 (22%)
Query: 18 ARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQ------------ 65
AR E+ + + +++ EA+ R R + A L LAE E RQRQ
Sbjct: 1909 ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE-EAKRQRQLAEEDAARQRAE 1967
Query: 66 -ELLVRGALRGAGGAGAAAPRAGELL---------------GEAAQRSRLEEKF------ 103
E ++ L G A A L EA QR RLEE+
Sbjct: 1968 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 2027
Query: 104 LEENILLLRKQLNCLRRRDAGL----LNQLQELDKQISDLRLDVEKTSEEHLETD 154
+EE + LRK + R GL L Q ++++++I L+ EK + E +
Sbjct: 2028 IEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE 2082
Score = 33.1 bits (74), Expect = 1.0
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 22 QRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGA 81
+++AE + + R + +A E+ R QEA AE LRQ+Q
Sbjct: 2255 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2314
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
+A R +LEE ++N LL ++L L+ Q ++++++ +R+
Sbjct: 2315 LRQKAQVEQELTTLRLQLEETDHQKN--LLDEELQRLKAEATEAARQRSQVEEELFSVRV 2372
Query: 142 DVEKTS--EEHLETDSR 156
+E+ S + +E ++R
Sbjct: 2373 QMEELSKLKARIEAENR 2389
Score = 32.7 bits (73), Expect = 1.4
Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 17/127 (13%)
Query: 405 GAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPKESP-SRGPAPPQEN 463
G A Q HLP PAS + R + + + P SP RGP P +E
Sbjct: 78 GIAHLRQYLHLPPEIVPASLQRVRRPVAMVMPARRTPHVQAVQGPLGSPPKRGPLPTEEQ 137
Query: 464 KVVQPLKKMSQKNSLQGVPPATPPLLST-----AFP-VEERPALDFKSEGSSQSLEE--- 514
+V + + L+ V P TP + +T A P E PA D + ++ +
Sbjct: 138 RVYR-------RKELEEVSPETPVVPATTQRTLARPGPEPAPATDERDRVQKKTFTKWVN 190
Query: 515 AHLVKAQ 521
HL+KAQ
Sbjct: 191 KHLIKAQ 197
Score = 31.2 bits (69), Expect = 4.0
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 34 KGEADTERQRTRERQEATLAGLAELEYLRQRQELLVR-------GALRGAGGAGAAAPRA 86
+GEA+ R+ E +EA + E R++ E R A A AA
Sbjct: 2217 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2276
Query: 87 GELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKT 146
E EAA+R++ E+ L + ++ ++ L Q +++++++ LRL +E+T
Sbjct: 2277 KEAEQEAARRAQAEQAALRQK-QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2335
Query: 147 SEE 149
+
Sbjct: 2336 DHQ 2338
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 25 AEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQR---QELLVRGALRGAGGAGA 81
AE + + +A+ E+Q+ +EA G AE + +RQR ++ L + G A
Sbjct: 1626 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1685
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
EL+ R R E + E+ LL ++L L+R A + QEL+ +++ +R
Sbjct: 1686 RLAAEQELI-----RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1740
Query: 142 DVE--KTSEEHLETDSRPSS 159
++E S+ E +SR +S
Sbjct: 1741 EMEVLLASKARAEEESRSTS 1760
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAG 80
E++ E + K +A+ E + ++R + + E Q+Q+ ++ L+ +
Sbjct: 1348 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1407
Query: 81 AAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLR 140
A +A EAA+RSRL +EE I ++R QL R+ G +LQ L + +
Sbjct: 1408 EAEIQAKARQAEAAERSRLR---IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE 1464
Query: 141 LDVEKTSEE 149
+ EE
Sbjct: 1465 AQKRQAQEE 1473
Score = 33.9 bits (76), Expect = 0.61
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 39/175 (22%)
Query: 18 ARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQ------------ 65
AR E+ + + +++ EA+ R R + A L LAE E RQRQ
Sbjct: 1750 ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE-EAKRQRQLAEEDAARQRAE 1808
Query: 66 -ELLVRGALRGAGGAGAAAPRAGELL---------------GEAAQRSRLEEKF------ 103
E ++ L G A A L EA QR RLEE+
Sbjct: 1809 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1868
Query: 104 LEENILLLRKQLNCLRRRDAGL----LNQLQELDKQISDLRLDVEKTSEEHLETD 154
+EE + LRK + R GL L Q ++++++I L+ EK + E +
Sbjct: 1869 IEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE 1923
Score = 33.1 bits (74), Expect = 1.0
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 22 QRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGA 81
+++AE + + R + +A E+ R QEA AE LRQ+Q
Sbjct: 2096 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2155
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
+A R +LEE ++N LL ++L L+ Q ++++++ +R+
Sbjct: 2156 LRQKAQVEQELTTLRLQLEETDHQKN--LLDEELQRLKAEATEAARQRSQVEEELFSVRV 2213
Query: 142 DVEKTS--EEHLETDSR 156
+E+ S + +E ++R
Sbjct: 2214 QMEELSKLKARIEAENR 2230
Score = 31.2 bits (69), Expect = 4.0
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 34 KGEADTERQRTRERQEATLAGLAELEYLRQRQELLVR-------GALRGAGGAGAAAPRA 86
+GEA+ R+ E +EA + E R++ E R A A AA
Sbjct: 2058 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2117
Query: 87 GELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKT 146
E EAA+R++ E+ L + ++ ++ L Q +++++++ LRL +E+T
Sbjct: 2118 KEAEQEAARRAQAEQAALRQK-QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2176
Query: 147 SEE 149
+
Sbjct: 2177 DHQ 2179
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 25 AEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQR---QELLVRGALRGAGGAGA 81
AE + + +A+ E+Q+ +EA G AE + +RQR ++ L + G A
Sbjct: 1634 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1693
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
EL+ R R E + E+ LL ++L L+R A + QEL+ +++ +R
Sbjct: 1694 RLAAEQELI-----RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1748
Query: 142 DVE--KTSEEHLETDSRPSS 159
++E S+ E +SR +S
Sbjct: 1749 EMEVLLASKARAEEESRSTS 1768
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAG 80
E++ E + K +A+ E + ++R + + E Q+Q+ ++ L+ +
Sbjct: 1356 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1415
Query: 81 AAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLR 140
A +A EAA+RSRL +EE I ++R QL R+ G +LQ L + +
Sbjct: 1416 EAEIQAKARQAEAAERSRLR---IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE 1472
Query: 141 LDVEKTSEE 149
+ EE
Sbjct: 1473 AQKRQAQEE 1481
Score = 33.9 bits (76), Expect = 0.61
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 39/175 (22%)
Query: 18 ARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQ------------ 65
AR E+ + + +++ EA+ R R + A L LAE E RQRQ
Sbjct: 1758 ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE-EAKRQRQLAEEDAARQRAE 1816
Query: 66 -ELLVRGALRGAGGAGAAAPRAGELL---------------GEAAQRSRLEEKF------ 103
E ++ L G A A L EA QR RLEE+
Sbjct: 1817 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1876
Query: 104 LEENILLLRKQLNCLRRRDAGL----LNQLQELDKQISDLRLDVEKTSEEHLETD 154
+EE + LRK + R GL L Q ++++++I L+ EK + E +
Sbjct: 1877 IEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE 1931
Score = 33.1 bits (74), Expect = 1.0
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 22 QRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGA 81
+++AE + + R + +A E+ R QEA AE LRQ+Q
Sbjct: 2104 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2163
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
+A R +LEE ++N LL ++L L+ Q ++++++ +R+
Sbjct: 2164 LRQKAQVEQELTTLRLQLEETDHQKN--LLDEELQRLKAEATEAARQRSQVEEELFSVRV 2221
Query: 142 DVEKTS--EEHLETDSR 156
+E+ S + +E ++R
Sbjct: 2222 QMEELSKLKARIEAENR 2238
Score = 31.2 bits (69), Expect = 4.0
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 34 KGEADTERQRTRERQEATLAGLAELEYLRQRQELLVR-------GALRGAGGAGAAAPRA 86
+GEA+ R+ E +EA + E R++ E R A A AA
Sbjct: 2066 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2125
Query: 87 GELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKT 146
E EAA+R++ E+ L + ++ ++ L Q +++++++ LRL +E+T
Sbjct: 2126 KEAEQEAARRAQAEQAALRQK-QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2184
Query: 147 SEE 149
+
Sbjct: 2185 DHQ 2187
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 25 AEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQR---QELLVRGALRGAGGAGA 81
AE + + +A+ E+Q+ +EA G AE + +RQR ++ L + G A
Sbjct: 1675 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1734
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
EL+ R R E + E+ LL ++L L+R A + QEL+ +++ +R
Sbjct: 1735 RLAAEQELI-----RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1789
Query: 142 DVE--KTSEEHLETDSRPSS 159
++E S+ E +SR +S
Sbjct: 1790 EMEVLLASKARAEEESRSTS 1809
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAG 80
E++ E + K +A+ E + ++R + + E Q+Q+ ++ L+ +
Sbjct: 1397 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1456
Query: 81 AAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLR 140
A +A EAA+RSRL +EE I ++R QL R+ G +LQ L + +
Sbjct: 1457 EAEIQAKARQAEAAERSRLR---IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE 1513
Query: 141 LDVEKTSEE 149
+ EE
Sbjct: 1514 AQKRQAQEE 1522
Score = 33.9 bits (76), Expect = 0.61
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 39/175 (22%)
Query: 18 ARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQ------------ 65
AR E+ + + +++ EA+ R R + A L LAE E RQRQ
Sbjct: 1799 ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE-EAKRQRQLAEEDAARQRAE 1857
Query: 66 -ELLVRGALRGAGGAGAAAPRAGELL---------------GEAAQRSRLEEKF------ 103
E ++ L G A A L EA QR RLEE+
Sbjct: 1858 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1917
Query: 104 LEENILLLRKQLNCLRRRDAGL----LNQLQELDKQISDLRLDVEKTSEEHLETD 154
+EE + LRK + R GL L Q ++++++I L+ EK + E +
Sbjct: 1918 IEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE 1972
Score = 33.1 bits (74), Expect = 1.0
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 22 QRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGA 81
+++AE + + R + +A E+ R QEA AE LRQ+Q
Sbjct: 2145 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2204
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
+A R +LEE ++N LL ++L L+ Q ++++++ +R+
Sbjct: 2205 LRQKAQVEQELTTLRLQLEETDHQKN--LLDEELQRLKAEATEAARQRSQVEEELFSVRV 2262
Query: 142 DVEKTS--EEHLETDSR 156
+E+ S + +E ++R
Sbjct: 2263 QMEELSKLKARIEAENR 2279
Score = 31.2 bits (69), Expect = 4.0
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 34 KGEADTERQRTRERQEATLAGLAELEYLRQRQELLVR-------GALRGAGGAGAAAPRA 86
+GEA+ R+ E +EA + E R++ E R A A AA
Sbjct: 2107 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2166
Query: 87 GELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKT 146
E EAA+R++ E+ L + ++ ++ L Q +++++++ LRL +E+T
Sbjct: 2167 KEAEQEAARRAQAEQAALRQK-QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2225
Query: 147 SEE 149
+
Sbjct: 2226 DHQ 2228
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 41.6 bits (96), Expect = 0.003
Identities = 81/381 (21%), Positives = 143/381 (37%), Gaps = 45/381 (11%)
Query: 316 VRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSV--------------NLKNSKQA 361
V+T+ +T A+P + + APG V + N +NS
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 362 CLPSGGIPSLNNGTFSP------PKQWSKESKAEQ-AESKRVPLPEGCPSGAASDLQSKH 414
+PS+ + P++ S S+ E +E + L + PSG +++
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 415 LPKTAKPASQEHARCSAIG-TGESPKESAQL--SGASPKESPSRGPAPPQEN--KVVQPL 469
P AK + ++ A + G TG S ++ + SG+S +ES S G AP +V++P
Sbjct: 901 AP--AKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPP 958
Query: 470 KKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQ--FIPGQQ 527
N P ATP A + A + + SS E+ ++ A PG +
Sbjct: 959 LIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIR 1018
Query: 528 PS-VRLHRGHRNM----GVVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLD 582
+ V + H + + SS K G + P + + G+ P
Sbjct: 1019 TNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTS 1078
Query: 583 -----TNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGHG----REAVVAKPK 633
TNK K + +++ PE+ + +GS G G + A P
Sbjct: 1079 VQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDS-SSGSEEDGEGPQGAKSAHTLGPT 1137
Query: 634 HKRTDYRRWKSSAEISYEEAL 654
RT+ +++AE S ++ +
Sbjct: 1138 PSRTETLVEETAAESSEDDVV 1158
Score = 32.7 bits (73), Expect = 1.4
Identities = 59/238 (24%), Positives = 83/238 (34%), Gaps = 32/238 (13%)
Query: 445 SGASPKESPSR--GPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALD 502
S S KESP+R PAP + V +K A PP P EE +
Sbjct: 226 SSVSTKESPARKAAPAPGKVGDVTPQVK-----------GGALPPAKRAKKPEEESES-- 272
Query: 503 FKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLP 562
SE S+S EEA + + +++ K + K PA G
Sbjct: 273 --SEEGSESEEEAPAGTRSQVKASEKILQVRAA---SAPAKGTPGKGATPAPPGKAG--- 324
Query: 563 TVREKTRAG------SKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRA 616
V +T+AG D + KA + + SG + G PA R
Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRK 384
Query: 617 GSRAHGHGR--EAVVAKPKHKRTDYRRWKSSAEISYEEALRRAR-RGRRENVGLYPAP 671
G+ G+ AV KR + + S S EEA +A+ G+ V AP
Sbjct: 385 GAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAP 442
Score = 32.0 bits (71), Expect = 2.3
Identities = 56/257 (21%), Positives = 90/257 (35%), Gaps = 13/257 (5%)
Query: 276 AVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRTSVNADPTKGLLR 335
A +T + P S S+ S S++ +L+Q K + S P K R
Sbjct: 327 ASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASA---PAKESPR 383
Query: 336 NGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKR 395
G+ AP G + G +V + + S ++ P Q KA Q +
Sbjct: 384 KGAA--PAPPGKT-GPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS 440
Query: 396 VPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPKESPSR 455
P E GAA K P A+ + S + ES + L+ + +
Sbjct: 441 APAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPL 500
Query: 456 GPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEA 515
G +P V+P M +G P P + A P + + SE SS+ ++
Sbjct: 501 GKSPQ-----VKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDS 555
Query: 516 H--LVKAQFIPGQQPSV 530
V P Q+ S+
Sbjct: 556 SDGEVPTAVAPAQEKSL 572
Score = 30.8 bits (68), Expect = 5.2
Identities = 34/152 (22%), Positives = 60/152 (39%), Gaps = 16/152 (10%)
Query: 359 KQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKT 418
+ A P+ G P T +PP + + A +++K E S + S+
Sbjct: 301 RAASAPAKGTPG-KGATPAPPGK----AGAVASQTKAGKPEEDSESSSEESSDSEEETPA 355
Query: 419 AKPASQEHA--RCSAIGTGESPKESAQLSGASPKESPSRGP--APPQENKVVQPLKKMSQ 474
AK Q A + S +G +P + + GA+P GP A Q K + + S+
Sbjct: 356 AKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415
Query: 475 KNSLQGVPPA-------TPPLLSTAFPVEERP 499
++ + PA P + + + P +E P
Sbjct: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
Score = 30.4 bits (67), Expect = 6.8
Identities = 40/188 (21%), Positives = 66/188 (35%), Gaps = 25/188 (13%)
Query: 369 PSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQ--------------SKH 414
P + G P K+ K + ++ + E P+G S ++ +K
Sbjct: 250 PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKG 309
Query: 415 LP-KTAKPASQEHARCSAIGT-GESPKESAQLSGASPKESPSRGPAPPQ--------ENK 464
P K A PA A A T P+E ++ S +S PA +
Sbjct: 310 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 369
Query: 465 VVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIP 524
V ++++ +G PA P A + + S+ SS+ + AQ P
Sbjct: 370 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKP 429
Query: 525 -GQQPSVR 531
G+ P VR
Sbjct: 430 SGKAPQVR 437
>gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]
Length = 1352
Score = 41.2 bits (95), Expect = 0.004
Identities = 78/329 (23%), Positives = 122/329 (37%), Gaps = 36/329 (10%)
Query: 347 VSQGNSVNLKNSKQACLPS--GGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPS 404
V Q +SV+ K+ PS G + T S+ E++ K P S
Sbjct: 992 VDQSDSVDSSPVKEVKAPSHPGSLAKKPESTTKRSPSSKGTSEPEKSLRKGRPALASQES 1051
Query: 405 GAASDLQSKHLPK--TAKPA-SQEHARCSAIGTGE--SPKESAQLSGASPKESPSRGPAP 459
+S S LP + KP+ S+ A S+ G+G SP + +SPK S
Sbjct: 1052 SLSSTSPSSPLPVKVSLKPSRSRSKADSSSRGSGRHSSPAPAQPKKESSPKSQDSVSSPS 1111
Query: 460 PQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALD--FKSEGSSQSLEEAHL 517
PQ+ K L + S + A+ P + FP + D EGS QSL
Sbjct: 1112 PQKQKSASALTYTASSTSAK---KASGPATRSPFPPGKSRTSDHSLSREGSRQSLGSDRA 1168
Query: 518 VKAQFIPGQQPSVRLHRGHRNMGV---VKNSSLKHRGPALQGLENGLPTVREKTRAGSKK 574
P V R G V++SS+ +++GL + +++ K
Sbjct: 1169 SATSTSKPNSPRVSQARAGEGRGAGKHVRSSSMASLRSPSTSIKSGL---KRDSKSEDKG 1225
Query: 575 CRFPDDLDTNKKLKKASSKG------RKSGGGPEAGV----PGRPAGGGHRAGS----RA 620
F K+ ++++ G +K+GG V A GH+ + A
Sbjct: 1226 LSFFKSALRQKETRRSTDLGKTALLSKKAGGSSVKSVCKNTGDDEAERGHQPPASQQPNA 1285
Query: 621 HGHGREAVVAK----PKHKRTDYRRWKSS 645
+ G+E +V K KH R+ KSS
Sbjct: 1286 NTTGKEQLVTKDPASAKHSLLSARKSKSS 1314
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 41.2 bits (95), Expect = 0.004
Identities = 28/117 (23%), Positives = 54/117 (46%), Gaps = 14/117 (11%)
Query: 40 ERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRL 99
E Q R+ ++ A L E +R+ L+ L E L A ++
Sbjct: 1701 EEQAGRDEEQRLAAELHEQAQALERRASLLAAEL--------------EELRAALEQGER 1746
Query: 100 EEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSR 156
+ E+ +L ++LN L ++ GLLNQ ++L+ ++ L +VE+ ++E E + +
Sbjct: 1747 SRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEK 1803
Score = 31.6 bits (70), Expect = 3.0
Identities = 44/180 (24%), Positives = 65/180 (36%), Gaps = 17/180 (9%)
Query: 11 ELEPPAPARGEQRTAEP-------EGRWREKGEADTERQRTRERQEATLAGLA-ELEYLR 62
E E A AR E++ AE R E G A ++ ++EA L L ELE
Sbjct: 1172 EAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAA 1231
Query: 63 QRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRD 122
R E V R A + L Q+ E+ L + L + L R
Sbjct: 1232 LRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAK 1291
Query: 123 AGLLNQLQELDKQISDLRLDVEK---------TSEEHLETDSRPSSGFYELSDGASGSLS 173
A + + Q+S+ ++ VE+ T L+T+S S E + LS
Sbjct: 1292 ASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLS 1351
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 40.8 bits (94), Expect = 0.005
Identities = 80/382 (20%), Positives = 143/382 (37%), Gaps = 46/382 (12%)
Query: 316 VRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSV--------------NLKNSKQA 361
V+T+ +T A+P + + APG V + N +NS
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 362 CLPSGGIPSLNNGTFSP------PKQWSKESKAEQ-AESKRVPLPEGCPSGAASDLQSKH 414
+PS+ + P++ S S+ E +E + L + PSG +++
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 415 LPKTAKPASQEHARCSAIG-TGESPKESAQL--SGASPKESPSRGPAPPQEN--KVVQPL 469
P AK + ++ A + G TG S ++ + SG+S +ES S G AP +V++P
Sbjct: 901 AP--AKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPP 958
Query: 470 KKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQ--FIPGQQ 527
N P ATP A + A + + SS E+ ++ A PG +
Sbjct: 959 LIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIR 1018
Query: 528 PS-VRLHRGHRNM----GVVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLD 582
+ V + H + + SS K G + P + + G+ P
Sbjct: 1019 TNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTS 1078
Query: 583 -----TNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGHGREA-----VVAKP 632
TNK K + +++ PE+ + +GS G G + + P
Sbjct: 1079 VQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDS-SSGSEEDGEGPQGAKSAHTLVGP 1137
Query: 633 KHKRTDYRRWKSSAEISYEEAL 654
RT+ +++AE S ++ +
Sbjct: 1138 TPSRTETLVEETAAESSEDDVV 1159
Score = 32.7 bits (73), Expect = 1.4
Identities = 59/238 (24%), Positives = 83/238 (34%), Gaps = 32/238 (13%)
Query: 445 SGASPKESPSR--GPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALD 502
S S KESP+R PAP + V +K A PP P EE +
Sbjct: 226 SSVSTKESPARKAAPAPGKVGDVTPQVK-----------GGALPPAKRAKKPEEESES-- 272
Query: 503 FKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLP 562
SE S+S EEA + + +++ K + K PA G
Sbjct: 273 --SEEGSESEEEAPAGTRSQVKASEKILQVRAA---SAPAKGTPGKGATPAPPGKAG--- 324
Query: 563 TVREKTRAG------SKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRA 616
V +T+AG D + KA + + SG + G PA R
Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRK 384
Query: 617 GSRAHGHGR--EAVVAKPKHKRTDYRRWKSSAEISYEEALRRAR-RGRRENVGLYPAP 671
G+ G+ AV KR + + S S EEA +A+ G+ V AP
Sbjct: 385 GAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAP 442
Score = 32.0 bits (71), Expect = 2.3
Identities = 56/257 (21%), Positives = 90/257 (35%), Gaps = 13/257 (5%)
Query: 276 AVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRTSVNADPTKGLLR 335
A +T + P S S+ S S++ +L+Q K + S P K R
Sbjct: 327 ASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASA---PAKESPR 383
Query: 336 NGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKR 395
G+ AP G + G +V + + S ++ P Q KA Q +
Sbjct: 384 KGAA--PAPPGKT-GPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS 440
Query: 396 VPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPKESPSR 455
P E GAA K P A+ + S + ES + L+ + +
Sbjct: 441 APAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPL 500
Query: 456 GPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEA 515
G +P V+P M +G P P + A P + + SE SS+ ++
Sbjct: 501 GKSPQ-----VKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDS 555
Query: 516 H--LVKAQFIPGQQPSV 530
V P Q+ S+
Sbjct: 556 SDGEVPTAVAPAQEKSL 572
Score = 30.8 bits (68), Expect = 5.2
Identities = 34/152 (22%), Positives = 60/152 (39%), Gaps = 16/152 (10%)
Query: 359 KQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKT 418
+ A P+ G P T +PP + + A +++K E S + S+
Sbjct: 301 RAASAPAKGTPG-KGATPAPPGK----AGAVASQTKAGKPEEDSESSSEESSDSEEETPA 355
Query: 419 AKPASQEHA--RCSAIGTGESPKESAQLSGASPKESPSRGP--APPQENKVVQPLKKMSQ 474
AK Q A + S +G +P + + GA+P GP A Q K + + S+
Sbjct: 356 AKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415
Query: 475 KNSLQGVPPA-------TPPLLSTAFPVEERP 499
++ + PA P + + + P +E P
Sbjct: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
Score = 30.4 bits (67), Expect = 6.8
Identities = 40/188 (21%), Positives = 66/188 (35%), Gaps = 25/188 (13%)
Query: 369 PSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQ--------------SKH 414
P + G P K+ K + ++ + E P+G S ++ +K
Sbjct: 250 PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKG 309
Query: 415 LP-KTAKPASQEHARCSAIGT-GESPKESAQLSGASPKESPSRGPAPPQ--------ENK 464
P K A PA A A T P+E ++ S +S PA +
Sbjct: 310 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 369
Query: 465 VVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIP 524
V ++++ +G PA P A + + S+ SS+ + AQ P
Sbjct: 370 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKP 429
Query: 525 -GQQPSVR 531
G+ P VR
Sbjct: 430 SGKAPQVR 437
>gi|47132529 suppression of tumorigenicity 5 isoform 1 [Homo
sapiens]
Length = 1137
Score = 40.8 bits (94), Expect = 0.005
Identities = 48/188 (25%), Positives = 65/188 (34%), Gaps = 23/188 (12%)
Query: 364 PSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPAS 423
P G+P L + +S + K E P+G AS A A
Sbjct: 296 PGRGLPQLPSSCYSVDRGKRKTGTLGSLEE---------PAGGASVSAGSRAVGVAGVAG 346
Query: 424 QEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLK-------KMSQKN 476
+ G+G S K + S + PS+ P N V +P + K +
Sbjct: 347 EAGPPPEREGSG-STKPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSK 405
Query: 477 SLQGVPP-----ATPPLLST-AFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSV 530
G+PP A PPL ST A PV RP D + SQS + A + PS
Sbjct: 406 PSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSS 465
Query: 531 RLHRGHRN 538
G N
Sbjct: 466 PTENGTEN 473
>gi|47132532 suppression of tumorigenicity 5 isoform 1 [Homo
sapiens]
Length = 1137
Score = 40.8 bits (94), Expect = 0.005
Identities = 48/188 (25%), Positives = 65/188 (34%), Gaps = 23/188 (12%)
Query: 364 PSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPAS 423
P G+P L + +S + K E P+G AS A A
Sbjct: 296 PGRGLPQLPSSCYSVDRGKRKTGTLGSLEE---------PAGGASVSAGSRAVGVAGVAG 346
Query: 424 QEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLK-------KMSQKN 476
+ G+G S K + S + PS+ P N V +P + K +
Sbjct: 347 EAGPPPEREGSG-STKPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSK 405
Query: 477 SLQGVPP-----ATPPLLST-AFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSV 530
G+PP A PPL ST A PV RP D + SQS + A + PS
Sbjct: 406 PSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSS 465
Query: 531 RLHRGHRN 538
G N
Sbjct: 466 PTENGTEN 473
>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
sapiens]
Length = 1038
Score = 40.4 bits (93), Expect = 0.007
Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 33/161 (20%)
Query: 344 PGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKE-SKAEQAE---------S 393
P G SQG + +QA P P L + F PP+ K S A+ AE
Sbjct: 660 PAGPSQGQTNYAFVPEQARPP----PPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECM 715
Query: 394 KRVPLPEGCPSGAAS---DLQSKHLPKTAKPA--SQEHARCSAIGTGESPKESAQLSG-A 447
+++ P G P+ + S D + + P+ P ++ H + S GE +E++Q G A
Sbjct: 716 RQLQAPAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGE--EETSQWPGPA 773
Query: 448 SPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPL 488
SP P R P PQ ++ PL VPP + PL
Sbjct: 774 SPPRVPPREPLSPQGSRTPSPL-----------VPPGSSPL 803
>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo
sapiens]
Length = 1086
Score = 40.4 bits (93), Expect = 0.007
Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 33/161 (20%)
Query: 344 PGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKE-SKAEQAE---------S 393
P G SQG + +QA P P L + F PP+ K S A+ AE
Sbjct: 738 PAGPSQGQTNYAFVPEQARPP----PPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECM 793
Query: 394 KRVPLPEGCPSGAAS---DLQSKHLPKTAKPA--SQEHARCSAIGTGESPKESAQLSG-A 447
+++ P G P+ + S D + + P+ P ++ H + S GE +E++Q G A
Sbjct: 794 RQLQAPAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGE--EETSQWPGPA 851
Query: 448 SPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPL 488
SP P R P PQ ++ PL VPP + PL
Sbjct: 852 SPPRVPPREPLSPQGSRTPSPL-----------VPPGSSPL 881
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 40.4 bits (93), Expect = 0.007
Identities = 75/309 (24%), Positives = 119/309 (38%), Gaps = 43/309 (13%)
Query: 279 TDSSLPSPSSLWSASHPSSSKKMDGYI-----LSLVQKKTHPVRTNKPRTSVNADPTKGL 333
++S+ P+P + P SS + + + SLV + H + KPR + P++G
Sbjct: 309 SESTTPAPPT----PRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPK--PSEG- 361
Query: 334 LRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAES 393
P + L ++ P+ PS + G PP Q S++ + E
Sbjct: 362 ---------TPAPRKDPPWITLVQAEPKKKPAPLPPSSSPG---PPSQDSRQVENGGTEE 409
Query: 394 KRVPLPEGC-PSGAASDLQSKHLPKTAK-PASQEHARCSAIGTGES-PKESAQLSGASPK 450
P P S + + + K + PA+ A A+G ES PK G +P
Sbjct: 410 VAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPT 469
Query: 451 ESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQ 510
SP P PL + + S P ATP S A VE SE +SQ
Sbjct: 470 SSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATP---SPALSVE-----SLSSESASQ 521
Query: 511 SLEEAHLVKAQFIP--GQQPSVRLHRGHRN-MGVVKNSSLKHRG----PALQGLENGLPT 563
+ A L++ +P +P+V N + + NSSL G P ++ + P
Sbjct: 522 T-AGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPG 580
Query: 564 VREKTRAGS 572
+ +TR S
Sbjct: 581 LAPRTRGSS 589
Score = 33.9 bits (76), Expect = 0.61
Identities = 65/316 (20%), Positives = 99/316 (31%), Gaps = 57/316 (18%)
Query: 208 PKSADVNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNPLREEDRLGNHASD 267
P S+ P V G + PSP +++S + NP EE+ +
Sbjct: 388 PSSSPGPPSQDSRQVENGGTEEVAQPSP--TASLESKPY------NPFEEEEEDKEEEAP 439
Query: 268 ICGG-SELDAVKTDSSLPSPSSLWSASHPSSSKKMD-------------GYILSLVQKKT 313
+ A+ S P W P+SS K S +
Sbjct: 440 AAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSE 499
Query: 314 HPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNN 373
P T P SV + ++ + + P V + +S P+ P
Sbjct: 500 PPSATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSE----------PAVHAPGTPG 549
Query: 374 GTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIG 433
S S S E E + +P+ P G A + P+ AKP S
Sbjct: 550 NPVSLSTNSSLASSGELVEPRVEQMPQASP-GLAPRTRGSSGPQPAKPCS---------- 598
Query: 434 TGESPKESAQLSGASPKESPSRGPAPPQE-----------NKVVQPLKKMSQKNSLQGVP 482
G +P + SP SP G + PQ N+ P + K + +G
Sbjct: 599 -GATPTPLLLVGDRSPVPSP--GSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSK 655
Query: 483 PATPPLLSTAFPVEER 498
P PP FP+ +R
Sbjct: 656 PVRPPAPGHGFPLIKR 671
Score = 32.0 bits (71), Expect = 2.3
Identities = 41/140 (29%), Positives = 54/140 (38%), Gaps = 20/140 (14%)
Query: 374 GTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIG 433
G FS PKQ ++ AE A+ +P G PS +A PK A P ++
Sbjct: 232 GPFSQPKQQHQQQLAEDAKD----VPGGGPSSSAPAGAEADGPK-ASPEARPQIPTKPRV 286
Query: 434 TGESPKESAQLSG----ASPKESPSRGPAPP---------QENKVVQPLKKMSQKNSLQG 480
G+ + ++ +G A K S S PAPP QEN V Q L
Sbjct: 287 PGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHE 346
Query: 481 VPPATPPLLSTAFPVEERPA 500
+P P T P E PA
Sbjct: 347 LP--VPKPRGTPKPSEGTPA 364
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 38.9 bits (89), Expect = 0.019
Identities = 48/157 (30%), Positives = 74/157 (47%), Gaps = 10/157 (6%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQE-LLVRGALRGAGGA 79
E+R E E R RE+ E E++ QE L + E LR+++E L + L G
Sbjct: 282 EERLCEQEERLREQEERLCEQEERLREQEERLC--EQEERLREQEERLCEQEKLPGQERL 339
Query: 80 GAAAPRAGELLGEAAQRSRL--EEKFLEENILLLRKQLNCLRRRDAGLLNQ--LQELDKQ 135
+ E ++ RL E+ LEE LL ++ LR++D L Q LQEL++
Sbjct: 340 LEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQER--LRQQDERLWQQETLQELER- 396
Query: 136 ISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSL 172
+ +L +E E E + P SGF EL++ +L
Sbjct: 397 LRELERMLELGWEALYEQRAEPRSGFEELNNENKSTL 433
Score = 32.0 bits (71), Expect = 2.3
Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 3/131 (2%)
Query: 19 RGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGG 78
R E+R E E R RE+ E E++ QE L + E LR+++E L R
Sbjct: 196 RQEERLREQEERLREQEERLREQEERLCEQEERLR--EQEERLREQEERLCEQEERLREH 253
Query: 79 AGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISD 138
+ E L E +R R +E+ L E L +Q LR ++ L Q + L +Q
Sbjct: 254 EERLCEQE-ERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEER 312
Query: 139 LRLDVEKTSEE 149
L E+ E+
Sbjct: 313 LCEQEERLREQ 323
>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
sapiens]
Length = 955
Score = 38.9 bits (89), Expect = 0.019
Identities = 55/231 (23%), Positives = 88/231 (38%), Gaps = 23/231 (9%)
Query: 259 DRLGNHASD--ICGGSELDAVKTDSSLPSPSSLW---SASHPSSSKKMDGYILSLVQK-- 311
D G+ A + GG+ D ++SS P P + + SAS S+ ++ S K
Sbjct: 195 DNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRERSPALKSP 254
Query: 312 -KTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVS------QGN----SVNLKNSKQ 360
++ VR PR S P+ L + P G QG S +L SK+
Sbjct: 255 LQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKK 314
Query: 361 ACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAK 420
+ P G P T+ ++ + A +KR + +G D + K T K
Sbjct: 315 S--PVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENG--KDKEQKQT-NTDK 369
Query: 421 PASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLKK 471
+E S G G+ +S + + E P RG P+ K+ +K
Sbjct: 370 EKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEK 420
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 38.9 bits (89), Expect = 0.019
Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 5/127 (3%)
Query: 386 SKAEQAESKRVPLPEGCPSGAASDLQSKHLP----KTAKPASQEHARCSAIGTGESPKES 441
S++ +R P P PS + P + ++ + R SA +G S S
Sbjct: 304 SRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSS 363
Query: 442 AQLSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPAL 501
+ S + PK+ P R +PP++ + + P ++ + PPATPP + P ++
Sbjct: 364 SSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRH-RPSPPATPPPKTRHSPTPQQSNR 422
Query: 502 DFKSEGS 508
KS S
Sbjct: 423 TRKSRVS 429
Score = 30.4 bits (67), Expect = 6.8
Identities = 45/227 (19%), Positives = 82/227 (36%), Gaps = 16/227 (7%)
Query: 353 VNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRV------PLPEGCPSGA 406
V + A L S ++ + SPPK+ K + + +++R+ P PS
Sbjct: 345 VRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPP 404
Query: 407 ASDL-QSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKV 465
A+ +++H P + +R S + G + + + G +ESPS P P KV
Sbjct: 405 ATPPPKTRHSPTPQQSNRTRKSRVS-VSPGRTSGKVTKHKGTEKRESPSPAPKP---RKV 460
Query: 466 VQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPG 525
++S+ +G A + + GSS S E+ ++ G
Sbjct: 461 -----ELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNG 515
Query: 526 QQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLPTVREKTRAGS 572
+ R H R+ K P + + P + R+ S
Sbjct: 516 EVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPS 562
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 38.9 bits (89), Expect = 0.019
Identities = 32/132 (24%), Positives = 52/132 (39%), Gaps = 18/132 (13%)
Query: 364 PSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPAS 423
P+ PS G PPK P P G + ++ K K + A+
Sbjct: 477 PASPCPSPGPGHTLPPKP---------------PSPRGTTASPKGRVRRKEEAKESPSAA 521
Query: 424 QEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPP 483
+ + + KESA + +P +PS PAPPQ+ QP + ++ PP
Sbjct: 522 GPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKE---QPPAETPTDAAVLTSPP 578
Query: 484 ATPPLLSTAFPV 495
A P ++ + P+
Sbjct: 579 APAPPVTPSKPM 590
Score = 30.0 bits (66), Expect = 8.8
Identities = 33/109 (30%), Positives = 40/109 (36%), Gaps = 15/109 (13%)
Query: 397 PLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSG-ASPKESPSR 455
P PEG PS + S +P T P A +A + + P E SG P+
Sbjct: 27 PSPEGDPSPPPPPM-SALVPDT--PPDTPPAMKNATSSKQLPLEPESPSGQVGPR----- 78
Query: 456 GPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLS-----TAFPVEERP 499
PAPPQE K G A PP S TA P + P
Sbjct: 79 -PAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSP 126
>gi|30795231 brain abundant, membrane attached signal protein 1
[Homo sapiens]
Length = 227
Score = 38.5 bits (88), Expect = 0.025
Identities = 49/208 (23%), Positives = 80/208 (38%), Gaps = 39/208 (18%)
Query: 349 QGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKR-VPLPEGCPSGAA 407
+G +VN + +K+ + G + GT PK+ ++ AE AE+K P+ G A
Sbjct: 10 KGYNVNDEKAKEKDKKAEGAATEEEGT---PKESEPQAAAEPAEAKEGKEKPDQDAEGKA 66
Query: 408 SDLQSK--------HLPKTA---------------KPASQEHARCSAIGTGESPKESAQL 444
+ + + PK K QE A GE+PK +
Sbjct: 67 EEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAA 126
Query: 445 SGASPKESPSRGPAPPQE----NKVVQPLKKMSQKNSLQGVPPA-TPPLLSTAFP----- 494
+ + +P+ G P +E K P +Q+ G P + + P S A P
Sbjct: 127 AAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKET 186
Query: 495 --VEERPALDFKSEGSSQSLEEAHLVKA 520
E P+ K++G + S EE V+A
Sbjct: 187 PAATEAPSSTPKAQGPAASAEEPKPVEA 214
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,475,089
Number of Sequences: 37866
Number of extensions: 1913152
Number of successful extensions: 10737
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 411
Number of HSP's that attempted gapping in prelim test: 9674
Number of HSP's gapped (non-prelim): 1398
length of query: 799
length of database: 18,247,518
effective HSP length: 110
effective length of query: 689
effective length of database: 14,082,258
effective search space: 9702675762
effective search space used: 9702675762
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.