Guide to the Human Genome
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Search of human proteins with 118200335

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|118200335 family with sequence similarity 127, member A
[Homo sapiens]
         (113 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|118200335 family with sequence similarity 127, member A [Homo...   235   6e-63
gi|118200333 family with sequence similarity 127, member B isofo...   223   2e-59
gi|239757911 PREDICTED: similar to Family with sequence similari...   222   4e-59
gi|118200337 family with sequence similarity 127, member C [Homo...   222   6e-59
gi|6912480 leucine zipper, down-regulated in cancer 1 [Homo sapi...   131   1e-31
gi|197245393 family with sequence similarity 127, member B isofo...   123   3e-29
gi|49355807 leucine zipper, down-regulated in cancer 1-like [Hom...    80   3e-16
gi|94421473 paternally expressed 10 isoform RF1 [Homo sapiens]         58   1e-09
gi|94421475 paternally expressed 10 isoform RF1/2 [Homo sapiens]       58   1e-09
gi|199562283 retrotransposon-like 1 [Homo sapiens]                     55   1e-08
gi|126157477 hypothetical protein LOC79680 [Homo sapiens]              54   3e-08
gi|22749387 zinc finger, CCHC domain containing 5 [Homo sapiens]       51   2e-07
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]     49   9e-07
gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]     27   2.7  
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]           26   6.0  
gi|11321577 2'-5'-oligoadenylate synthetase-like isoform a [Homo...    26   6.0  
gi|38788380 dehydrogenase E1 and transketolase domain containing...    26   7.8  
gi|193804850 dehydrogenase/reductase (SDR family) X-linked [Homo...    26   7.8  
gi|19923442 transmembrane emp24 protein transport domain contain...    26   7.8  
gi|122937187 glycosyltransferase 8 domain containing 4 [Homo sap...    26   7.8  

>gi|118200335 family with sequence similarity 127, member A [Homo
           sapiens]
          Length = 113

 Score =  235 bits (599), Expect = 6e-63
 Identities = 113/113 (100%), Positives = 113/113 (100%)

Query: 1   MDGRVQLIKALLALPIRPATRRWRNPIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSS 60
           MDGRVQLIKALLALPIRPATRRWRNPIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSS
Sbjct: 1   MDGRVQLIKALLALPIRPATRRWRNPIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSS 60

Query: 61  DALKVTFLITRLTGPALQWVIPYIKKESPLLNDYRGFLAEMKRVFGWEEDEDF 113
           DALKVTFLITRLTGPALQWVIPYIKKESPLLNDYRGFLAEMKRVFGWEEDEDF
Sbjct: 61  DALKVTFLITRLTGPALQWVIPYIKKESPLLNDYRGFLAEMKRVFGWEEDEDF 113


>gi|118200333 family with sequence similarity 127, member B isoform
           1 [Homo sapiens]
          Length = 113

 Score =  223 bits (569), Expect = 2e-59
 Identities = 106/113 (93%), Positives = 110/113 (97%)

Query: 1   MDGRVQLIKALLALPIRPATRRWRNPIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSS 60
           MDGRVQL+KALLA P+RPA RRWRNPIPFPETFDGDTDRLPEFIVQT SYMFVDENTFS+
Sbjct: 1   MDGRVQLMKALLAGPLRPAARRWRNPIPFPETFDGDTDRLPEFIVQTSSYMFVDENTFSN 60

Query: 61  DALKVTFLITRLTGPALQWVIPYIKKESPLLNDYRGFLAEMKRVFGWEEDEDF 113
           DALKVTFLITRLTGPALQWVIPYI+KESPLLNDYRGFLAEMKRVFGWEEDEDF
Sbjct: 61  DALKVTFLITRLTGPALQWVIPYIRKESPLLNDYRGFLAEMKRVFGWEEDEDF 113


>gi|239757911 PREDICTED: similar to Family with sequence similarity
           127, member B [Homo sapiens]
          Length = 113

 Score =  222 bits (566), Expect = 4e-59
 Identities = 106/113 (93%), Positives = 110/113 (97%)

Query: 1   MDGRVQLIKALLALPIRPATRRWRNPIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSS 60
           MDGRVQL+KALLA P+RPA RRWRNPIPFPETFDGDTDRLPEFIVQT SYMFVDENTFS+
Sbjct: 1   MDGRVQLMKALLAGPLRPAARRWRNPIPFPETFDGDTDRLPEFIVQTCSYMFVDENTFSN 60

Query: 61  DALKVTFLITRLTGPALQWVIPYIKKESPLLNDYRGFLAEMKRVFGWEEDEDF 113
           DALKVTFLITRLTGPALQWVIPYI+KESPLLNDYRGFLAEMKRVFGWEEDEDF
Sbjct: 61  DALKVTFLITRLTGPALQWVIPYIRKESPLLNDYRGFLAEMKRVFGWEEDEDF 113


>gi|118200337 family with sequence similarity 127, member C [Homo
           sapiens]
          Length = 113

 Score =  222 bits (565), Expect = 6e-59
 Identities = 105/113 (92%), Positives = 110/113 (97%)

Query: 1   MDGRVQLIKALLALPIRPATRRWRNPIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSS 60
           M+GRVQL+KALLA P+RPA RRWRNPIPFPETFDGDTDRLPEFIVQT SYMFVDENTFS+
Sbjct: 1   MEGRVQLMKALLARPLRPAARRWRNPIPFPETFDGDTDRLPEFIVQTSSYMFVDENTFSN 60

Query: 61  DALKVTFLITRLTGPALQWVIPYIKKESPLLNDYRGFLAEMKRVFGWEEDEDF 113
           DALKVTFLITRLTGPALQWVIPYIKKESPLL+DYRGFLAEMKRVFGWEEDEDF
Sbjct: 61  DALKVTFLITRLTGPALQWVIPYIKKESPLLSDYRGFLAEMKRVFGWEEDEDF 113


>gi|6912480 leucine zipper, down-regulated in cancer 1 [Homo
           sapiens]
          Length = 146

 Score =  131 bits (330), Expect = 1e-31
 Identities = 61/104 (58%), Positives = 80/104 (76%), Gaps = 4/104 (3%)

Query: 9   KALLALPIRPATRRWRNPIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSSDALKVTFL 68
           +A L   +RP +     P+PFPETF+G++ RLPEFIVQT SYM V+EN F +DA+KV FL
Sbjct: 37  RASLLRQVRPPSC----PVPFPETFNGESSRLPEFIVQTASYMLVNENRFCNDAMKVAFL 92

Query: 69  ITRLTGPALQWVIPYIKKESPLLNDYRGFLAEMKRVFGWEEDED 112
           I+ LTG A +WV+PYI+ +SP+L DYR FL EMK+ FGW++DED
Sbjct: 93  ISLLTGEAEEWVVPYIEMDSPILGDYRAFLDEMKQCFGWDDDED 136


>gi|197245393 family with sequence similarity 127, member B
          isoform 2 [Homo sapiens]
          Length = 83

 Score =  123 bits (309), Expect = 3e-29
 Identities = 58/64 (90%), Positives = 61/64 (95%)

Query: 1  MDGRVQLIKALLALPIRPATRRWRNPIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSS 60
          MDGRVQL+KALLA P+RPA RRWRNPIPFPETFDGDTDRLPEFIVQT SYMFVDENTFS+
Sbjct: 1  MDGRVQLMKALLAGPLRPAARRWRNPIPFPETFDGDTDRLPEFIVQTSSYMFVDENTFSN 60

Query: 61 DALK 64
          DALK
Sbjct: 61 DALK 64


>gi|49355807 leucine zipper, down-regulated in cancer 1-like [Homo
           sapiens]
          Length = 239

 Score = 80.1 bits (196), Expect = 3e-16
 Identities = 35/80 (43%), Positives = 53/80 (66%)

Query: 26  PIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSSDALKVTFLITRLTGPALQWVIPYIK 85
           P   PE F GD  RL  F++Q   +M    + F  +A +V FL++RLTG A +W IP+++
Sbjct: 98  PTSLPEPFSGDPGRLAGFLMQMDRFMIFQASRFPGEAERVAFLVSRLTGEAEKWAIPHMQ 157

Query: 86  KESPLLNDYRGFLAEMKRVF 105
            +SPL N+Y+GFLAE++R +
Sbjct: 158 PDSPLRNNYQGFLAELRRTY 177


>gi|94421473 paternally expressed 10 isoform RF1 [Homo sapiens]
          Length = 325

 Score = 58.2 bits (139), Expect = 1e-09
 Identities = 28/80 (35%), Positives = 44/80 (55%)

Query: 26  PIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSSDALKVTFLITRLTGPALQWVIPYIK 85
           P   PE FDG+ D L  F+ Q   +M      FS D ++V F+ + +TG A +W    ++
Sbjct: 79  PEDLPEKFDGNPDMLAPFMAQCQIFMEKSTRDFSVDRVRVCFVTSMMTGRAARWASAKLE 138

Query: 86  KESPLLNDYRGFLAEMKRVF 105
           +   L+++Y  F+ EMK VF
Sbjct: 139 RSHYLMHNYPAFMMEMKHVF 158


>gi|94421475 paternally expressed 10 isoform RF1/2 [Homo sapiens]
          Length = 708

 Score = 58.2 bits (139), Expect = 1e-09
 Identities = 28/80 (35%), Positives = 44/80 (55%)

Query: 26  PIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSSDALKVTFLITRLTGPALQWVIPYIK 85
           P   PE FDG+ D L  F+ Q   +M      FS D ++V F+ + +TG A +W    ++
Sbjct: 79  PEDLPEKFDGNPDMLAPFMAQCQIFMEKSTRDFSVDRVRVCFVTSMMTGRAARWASAKLE 138

Query: 86  KESPLLNDYRGFLAEMKRVF 105
           +   L+++Y  F+ EMK VF
Sbjct: 139 RSHYLMHNYPAFMMEMKHVF 158


>gi|199562283 retrotransposon-like 1 [Homo sapiens]
          Length = 1358

 Score = 55.1 bits (131), Expect = 1e-08
 Identities = 28/83 (33%), Positives = 44/83 (53%)

Query: 27  IPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSSDALKVTFLITRLTGPALQWVIPYIKK 86
           +P P+ F GD     EFIV     +      F +D L+V ++I  L+G AL+W    +++
Sbjct: 200 LPAPKHFSGDRREFHEFIVLCQLTLQSYPRMFYNDRLRVGYVINHLSGLALEWAKALLQE 259

Query: 87  ESPLLNDYRGFLAEMKRVFGWEE 109
            SPL+ D+  FL  M  VF + +
Sbjct: 260 NSPLIGDFPAFLEAMSEVFEYRQ 282


>gi|126157477 hypothetical protein LOC79680 [Homo sapiens]
          Length = 364

 Score = 53.9 bits (128), Expect = 3e-08
 Identities = 27/75 (36%), Positives = 38/75 (50%)

Query: 30  PETFDGDTDRLPEFIVQTGSYMFVDENTFSSDALKVTFLITRLTGPALQWVIPYIKKESP 89
           P TFDG    L  F+ Q G YM      +  +  +V  ++ RLTG A  W  PY+  + P
Sbjct: 104 PGTFDGSPWLLDRFLAQLGDYMSFHFEHYQDNISRVCEILRRLTGRAQAWAAPYLDGDLP 163

Query: 90  LLNDYRGFLAEMKRV 104
           L +DY  F  ++K V
Sbjct: 164 LPDDYELFCQDLKEV 178


>gi|22749387 zinc finger, CCHC domain containing 5 [Homo sapiens]
          Length = 475

 Score = 51.2 bits (121), Expect = 2e-07
 Identities = 27/80 (33%), Positives = 44/80 (55%)

Query: 26  PIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSSDALKVTFLITRLTGPALQWVIPYIK 85
           P+ +  TF GD+ +LPEF+VQ  SYM V  + + ++A  V+F+    +G A  W    + 
Sbjct: 237 PLQYTLTFSGDSQKLPEFLVQLYSYMRVRGHLYPTEAALVSFVGNCFSGRAGWWFQLLLD 296

Query: 86  KESPLLNDYRGFLAEMKRVF 105
            +SPLL     F+  ++  F
Sbjct: 297 IQSPLLEQCESFIPVLQDTF 316


>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
          Length = 569

 Score = 48.9 bits (115), Expect = 9e-07
 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 6/91 (6%)

Query: 15  PIRPATRRWRNPIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSSDALKVTFLITRLTG 74
           P+ P  R      P  E F GD   L EF++Q  +++   E  F   A +V FLI+  TG
Sbjct: 144 PLAPLER------PEIEPFSGDPVYLAEFLMQLETFIADHEVHFPGGAERVAFLISFFTG 197

Query: 75  PALQWVIPYIKKESPLLNDYRGFLAEMKRVF 105
            A  W I   ++ SPL  ++  FL E+++ F
Sbjct: 198 EAKDWAISVTQEGSPLHANFPRFLDEIRKEF 228


>gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]
          Length = 1388

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 12/48 (25%), Positives = 26/48 (54%)

Query: 58   FSSDALKVTFLITRLTGPALQWVIPYIKKESPLLNDYRGFLAEMKRVF 105
            F  D+ ++ FL++   G A +W I  ++   PL ++ + FL   + ++
Sbjct: 1179 FLDDSERMAFLVSLHLGAAERWFILQMEVGEPLSHENKSFLRRSQGIY 1226


>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
          Length = 3565

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 3/65 (4%)

Query: 31   ETFDGDTDRLPEFIVQTGSYMFVDENTFSSDALKVTFLITRLT---GPALQWVIPYIKKE 87
            E FDG + + P  +V +G++      T  S+ L + +     T   G  +++  PY    
Sbjct: 2377 EVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLT 2436

Query: 88   SPLLN 92
             PL N
Sbjct: 2437 HPLKN 2441


>gi|11321577 2'-5'-oligoadenylate synthetase-like isoform a [Homo
           sapiens]
          Length = 514

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 13/39 (33%), Positives = 19/39 (48%), Gaps = 4/39 (10%)

Query: 79  WVIPYIKKESPLLNDYRGFLAEMKRVFGW----EEDEDF 113
           W   Y+K  SP  N    +  E+  ++ W    EEDE+F
Sbjct: 216 WYQQYVKARSPRANLPPLYALELLTIYAWEMGTEEDENF 254


>gi|38788380 dehydrogenase E1 and transketolase domain containing 1
           [Homo sapiens]
          Length = 919

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 14/38 (36%), Positives = 17/38 (44%)

Query: 3   GRVQLIKALLALPIRPATRRWRNPIPFPETFDGDTDRL 40
           GR+ L+  LL  P     R+ R    FPE F    D L
Sbjct: 225 GRLNLLTGLLQFPPELMFRKMRGLSEFPENFSATGDVL 262


>gi|193804850 dehydrogenase/reductase (SDR family) X-linked [Homo
           sapiens]
          Length = 330

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 19/73 (26%), Positives = 29/73 (39%), Gaps = 3/73 (4%)

Query: 37  TDRLPEFIVQTGSYM---FVDENTFSSDALKVTFLITRLTGPALQWVIPYIKKESPLLND 93
           T  L   +   GS++    VD    ++D  K  F  TRL    L W++     E    + 
Sbjct: 219 TYHLQRLLAAEGSHVTANVVDPGVVNTDVYKHVFWATRLAKKLLGWLLFKTPDEGAWTSI 278

Query: 94  YRGFLAEMKRVFG 106
           Y     E++ V G
Sbjct: 279 YAAVTPELEGVGG 291


>gi|19923442 transmembrane emp24 protein transport domain containing
           5 [Homo sapiens]
          Length = 229

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 11/22 (50%), Positives = 15/22 (68%)

Query: 46  QTGSYMFVDENTFSSDALKVTF 67
           + G YMF  +NTFS+ + KV F
Sbjct: 100 EVGDYMFCFDNTFSTISEKVIF 121


>gi|122937187 glycosyltransferase 8 domain containing 4 [Homo
          sapiens]
          Length = 443

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 11/23 (47%), Positives = 14/23 (60%)

Query: 13 ALPIRPATRRWRNPIPFPETFDG 35
          ALP RPA+   R+P P P  + G
Sbjct: 34 ALPARPASAPQRHPAPVPARWPG 56


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.142    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,651,727
Number of Sequences: 37866
Number of extensions: 188712
Number of successful extensions: 312
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 294
Number of HSP's gapped (non-prelim): 21
length of query: 113
length of database: 18,247,518
effective HSP length: 83
effective length of query: 30
effective length of database: 15,104,640
effective search space: 453139200
effective search space used: 453139200
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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