Guide to the Human Genome
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Search of human proteins with 239751580

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239751580 PREDICTED: hypothetical protein [Homo sapiens]
         (195 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239757070 PREDICTED: hypothetical protein [Homo sapiens]           414   e-116
gi|239751580 PREDICTED: hypothetical protein [Homo sapiens]           414   e-116
gi|239746092 PREDICTED: hypothetical protein XP_002343656 [Homo ...   414   e-116
gi|4504733 insulin receptor substrate 4 [Homo sapiens]                 45   5e-05
gi|76781485 vascular endothelial growth factor A isoform f precu...    45   5e-05
gi|76781484 vascular endothelial growth factor A isoform e precu...    45   5e-05
gi|76781483 vascular endothelial growth factor A isoform d precu...    45   5e-05
gi|76781482 vascular endothelial growth factor A isoform c precu...    45   5e-05
gi|76781481 vascular endothelial growth factor A isoform b precu...    45   5e-05
gi|76781480 vascular endothelial growth factor A isoform a precu...    45   5e-05
gi|76781487 vascular endothelial growth factor A isoform g precu...    45   5e-05
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             42   3e-04
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...    42   3e-04
gi|169171347 PREDICTED: hypothetical protein [Homo sapiens]            42   4e-04
gi|239753418 PREDICTED: similar to hCG2012845 [Homo sapiens]           42   4e-04
gi|169172209 PREDICTED: hypothetical protein [Homo sapiens]            42   4e-04
gi|169170953 PREDICTED: hypothetical protein [Homo sapiens]            42   4e-04
gi|239743069 PREDICTED: hypothetical protein XP_002342750 [Homo ...    42   4e-04
gi|239508753 PREDICTED: hypothetical protein [Homo sapiens]            42   4e-04
gi|239508715 PREDICTED: hypothetical protein [Homo sapiens]            42   4e-04
gi|239752810 PREDICTED: hypothetical protein [Homo sapiens]            40   0.001
gi|157676331 hyaluronan binding protein 4 [Homo sapiens]               40   0.001
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    40   0.002
gi|239754489 PREDICTED: hypothetical protein [Homo sapiens]            40   0.002
gi|239754138 PREDICTED: hypothetical protein [Homo sapiens]            40   0.002
gi|239742631 PREDICTED: hypothetical protein XP_002342600 [Homo ...    40   0.002
gi|124107614 PR domain containing 13 [Homo sapiens]                    40   0.002
gi|239750468 PREDICTED: similar to Os05g0242100 [Homo sapiens]         39   0.002
gi|150378549 tangerin [Homo sapiens]                                   39   0.002
gi|60097902 filaggrin [Homo sapiens]                                   39   0.003

>gi|239757070 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 195

 Score =  414 bits (1064), Expect = e-116
 Identities = 195/195 (100%), Positives = 195/195 (100%)

Query: 1   MHFPMPLEPPATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGR 60
           MHFPMPLEPPATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGR
Sbjct: 1   MHFPMPLEPPATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGR 60

Query: 61  AGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVG 120
           AGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVG
Sbjct: 61  AGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVG 120

Query: 121 RHRHRHRHHCQNRLSGVAGCLPLPRPRDGARSPQPLPWKPGLPSLCVASGLRTAPDASAP 180
           RHRHRHRHHCQNRLSGVAGCLPLPRPRDGARSPQPLPWKPGLPSLCVASGLRTAPDASAP
Sbjct: 121 RHRHRHRHHCQNRLSGVAGCLPLPRPRDGARSPQPLPWKPGLPSLCVASGLRTAPDASAP 180

Query: 181 GRAAKTRSSGARMAS 195
           GRAAKTRSSGARMAS
Sbjct: 181 GRAAKTRSSGARMAS 195


>gi|239751580 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 195

 Score =  414 bits (1064), Expect = e-116
 Identities = 195/195 (100%), Positives = 195/195 (100%)

Query: 1   MHFPMPLEPPATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGR 60
           MHFPMPLEPPATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGR
Sbjct: 1   MHFPMPLEPPATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGR 60

Query: 61  AGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVG 120
           AGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVG
Sbjct: 61  AGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVG 120

Query: 121 RHRHRHRHHCQNRLSGVAGCLPLPRPRDGARSPQPLPWKPGLPSLCVASGLRTAPDASAP 180
           RHRHRHRHHCQNRLSGVAGCLPLPRPRDGARSPQPLPWKPGLPSLCVASGLRTAPDASAP
Sbjct: 121 RHRHRHRHHCQNRLSGVAGCLPLPRPRDGARSPQPLPWKPGLPSLCVASGLRTAPDASAP 180

Query: 181 GRAAKTRSSGARMAS 195
           GRAAKTRSSGARMAS
Sbjct: 181 GRAAKTRSSGARMAS 195


>gi|239746092 PREDICTED: hypothetical protein XP_002343656 [Homo
           sapiens]
          Length = 195

 Score =  414 bits (1064), Expect = e-116
 Identities = 195/195 (100%), Positives = 195/195 (100%)

Query: 1   MHFPMPLEPPATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGR 60
           MHFPMPLEPPATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGR
Sbjct: 1   MHFPMPLEPPATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGR 60

Query: 61  AGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVG 120
           AGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVG
Sbjct: 61  AGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVG 120

Query: 121 RHRHRHRHHCQNRLSGVAGCLPLPRPRDGARSPQPLPWKPGLPSLCVASGLRTAPDASAP 180
           RHRHRHRHHCQNRLSGVAGCLPLPRPRDGARSPQPLPWKPGLPSLCVASGLRTAPDASAP
Sbjct: 121 RHRHRHRHHCQNRLSGVAGCLPLPRPRDGARSPQPLPWKPGLPSLCVASGLRTAPDASAP 180

Query: 181 GRAAKTRSSGARMAS 195
           GRAAKTRSSGARMAS
Sbjct: 181 GRAAKTRSSGARMAS 195


>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
          Length = 1257

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 32/99 (32%), Positives = 42/99 (42%), Gaps = 3/99 (3%)

Query: 19  GQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQGAQGWAAARRES 78
           G G G G+   +    Q    H  GG+Q      G G+R G+ G+ GQG+ G   +R   
Sbjct: 494 GSGNGRGSGGGQGSNGQGSSSHSSGGNQCS--GEGQGSRGGQ-GSNGQGSGGNQCSRDGQ 550

Query: 79  RAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRG 117
             AGG     G R G G G G  + P       GG + G
Sbjct: 551 GTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSG 589



 Score = 30.8 bits (68), Expect = 0.76
 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 10/82 (12%)

Query: 19  GQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQGAQGWAAARRES 78
           G G G   +E     ++  EG   GG      + G G  +GR    GQG+ G  ++   S
Sbjct: 462 GSGSGNFGEEGNPQGKEDQEG--SGGDYMPMNNWGSG--NGRGSGGGQGSNGQGSS---S 514

Query: 79  RAAGGRLECLGLRAGAGRGGGE 100
            ++GG  +C G   G G  GG+
Sbjct: 515 HSSGGN-QCSG--EGQGSRGGQ 533



 Score = 29.6 bits (65), Expect = 1.7
 Identities = 22/91 (24%), Positives = 34/91 (37%), Gaps = 14/91 (15%)

Query: 21  GEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQGAQGWAAARRESRA 80
           G+G G ++     Q    GH  GG Q+     G G   G     G G             
Sbjct: 537 GQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSG------------- 583

Query: 81  AGGRLECLGLRAGAGRGGGEEEEPARAPPRR 111
            GG+    G  +G+G+G   + E  ++  +R
Sbjct: 584 -GGKNSGGGKGSGSGKGSDGDGERGKSLKKR 613


>gi|76781485 vascular endothelial growth factor A isoform f
           precursor [Homo sapiens]
          Length = 327

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 35/116 (30%), Positives = 50/116 (43%), Gaps = 18/116 (15%)

Query: 16  MRPGQGEGLGA---------DERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQ 66
           +R G+ E  GA         + +    +++ E  EE G Q +  +  PG+ +G A     
Sbjct: 69  VRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWTGEAAVCAD 128

Query: 67  GAQGWAAARRESRAAGGRLECLGLRAG-AGRGGGEEEEPARAPPRRGGASRGRVGR 121
            A    A +  +RA+G        R G   R G EE  P  +P RRG ASR   GR
Sbjct: 129 SAPAARAPQALARASG--------RGGRVARRGAEESGPPHSPSRRGSASRAGPGR 176


>gi|76781484 vascular endothelial growth factor A isoform e
           precursor [Homo sapiens]
          Length = 354

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 35/116 (30%), Positives = 50/116 (43%), Gaps = 18/116 (15%)

Query: 16  MRPGQGEGLGA---------DERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQ 66
           +R G+ E  GA         + +    +++ E  EE G Q +  +  PG+ +G A     
Sbjct: 69  VRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWTGEAAVCAD 128

Query: 67  GAQGWAAARRESRAAGGRLECLGLRAG-AGRGGGEEEEPARAPPRRGGASRGRVGR 121
            A    A +  +RA+G        R G   R G EE  P  +P RRG ASR   GR
Sbjct: 129 SAPAARAPQALARASG--------RGGRVARRGAEESGPPHSPSRRGSASRAGPGR 176


>gi|76781483 vascular endothelial growth factor A isoform d
           precursor [Homo sapiens]
          Length = 371

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 35/116 (30%), Positives = 50/116 (43%), Gaps = 18/116 (15%)

Query: 16  MRPGQGEGLGA---------DERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQ 66
           +R G+ E  GA         + +    +++ E  EE G Q +  +  PG+ +G A     
Sbjct: 69  VRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWTGEAAVCAD 128

Query: 67  GAQGWAAARRESRAAGGRLECLGLRAG-AGRGGGEEEEPARAPPRRGGASRGRVGR 121
            A    A +  +RA+G        R G   R G EE  P  +P RRG ASR   GR
Sbjct: 129 SAPAARAPQALARASG--------RGGRVARRGAEESGPPHSPSRRGSASRAGPGR 176


>gi|76781482 vascular endothelial growth factor A isoform c
           precursor [Homo sapiens]
          Length = 389

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 35/116 (30%), Positives = 50/116 (43%), Gaps = 18/116 (15%)

Query: 16  MRPGQGEGLGA---------DERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQ 66
           +R G+ E  GA         + +    +++ E  EE G Q +  +  PG+ +G A     
Sbjct: 69  VRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWTGEAAVCAD 128

Query: 67  GAQGWAAARRESRAAGGRLECLGLRAG-AGRGGGEEEEPARAPPRRGGASRGRVGR 121
            A    A +  +RA+G        R G   R G EE  P  +P RRG ASR   GR
Sbjct: 129 SAPAARAPQALARASG--------RGGRVARRGAEESGPPHSPSRRGSASRAGPGR 176


>gi|76781481 vascular endothelial growth factor A isoform b
           precursor [Homo sapiens]
          Length = 395

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 35/116 (30%), Positives = 50/116 (43%), Gaps = 18/116 (15%)

Query: 16  MRPGQGEGLGA---------DERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQ 66
           +R G+ E  GA         + +    +++ E  EE G Q +  +  PG+ +G A     
Sbjct: 69  VRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWTGEAAVCAD 128

Query: 67  GAQGWAAARRESRAAGGRLECLGLRAG-AGRGGGEEEEPARAPPRRGGASRGRVGR 121
            A    A +  +RA+G        R G   R G EE  P  +P RRG ASR   GR
Sbjct: 129 SAPAARAPQALARASG--------RGGRVARRGAEESGPPHSPSRRGSASRAGPGR 176


>gi|76781480 vascular endothelial growth factor A isoform a
           precursor [Homo sapiens]
          Length = 412

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 35/116 (30%), Positives = 50/116 (43%), Gaps = 18/116 (15%)

Query: 16  MRPGQGEGLGA---------DERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQ 66
           +R G+ E  GA         + +    +++ E  EE G Q +  +  PG+ +G A     
Sbjct: 69  VRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWTGEAAVCAD 128

Query: 67  GAQGWAAARRESRAAGGRLECLGLRAG-AGRGGGEEEEPARAPPRRGGASRGRVGR 121
            A    A +  +RA+G        R G   R G EE  P  +P RRG ASR   GR
Sbjct: 129 SAPAARAPQALARASG--------RGGRVARRGAEESGPPHSPSRRGSASRAGPGR 176


>gi|76781487 vascular endothelial growth factor A isoform g
           precursor [Homo sapiens]
          Length = 371

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 35/116 (30%), Positives = 50/116 (43%), Gaps = 18/116 (15%)

Query: 16  MRPGQGEGLGA---------DERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQ 66
           +R G+ E  GA         + +    +++ E  EE G Q +  +  PG+ +G A     
Sbjct: 69  VRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWTGEAAVCAD 128

Query: 67  GAQGWAAARRESRAAGGRLECLGLRAG-AGRGGGEEEEPARAPPRRGGASRGRVGR 121
            A    A +  +RA+G        R G   R G EE  P  +P RRG ASR   GR
Sbjct: 129 SAPAARAPQALARASG--------RGGRVARRGAEESGPPHSPSRRGSASRAGPGR 176


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 53/205 (25%), Positives = 69/205 (33%), Gaps = 40/205 (19%)

Query: 8   EPPATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQG 67
           E P    H R   G         H+   +         + + R  G    SG    +  G
Sbjct: 246 ESPGRRSH-RHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSG 304

Query: 68  AQGWAAARRESRAAGGRLECLGLRAGAGRG--------------------------GGEE 101
             GW + +R    +G R    G R G+                             G E 
Sbjct: 305 GSGWGSPQRNG-GSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKES 363

Query: 102 EEPARAPPR--RGGASRGRVGRHRHRHRHHCQNRLSGVAGCLPLPRPRDGARSPQPLPWK 159
             P  AP    RGG + G  GR R R R   ++R S  A     PR R G R P+P P +
Sbjct: 364 PSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASA-----PR-RRGRRRPRPAPPR 417

Query: 160 PGLPSLCVASGLRTAPDASAPGRAA 184
               SL   S  R++ D S  GR A
Sbjct: 418 GSSRSL---SRARSSSD-SGSGRGA 438



 Score = 33.5 bits (75), Expect = 0.12
 Identities = 44/199 (22%), Positives = 70/199 (35%), Gaps = 21/199 (10%)

Query: 4   PMPLEPPATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGA 63
           P+  +  +   H R     G     R      + +  E+   +++  +  PG RS R  +
Sbjct: 198 PLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSS 257

Query: 64  AGQGAQGWAAARRESRA---AGGRLECLGLRAGAGRGGGEEEEPAR-----APPRRGGAS 115
               +   ++   +SR+      +    G + G+ R  G              P+R G S
Sbjct: 258 GSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGS 317

Query: 116 RGRVGRH--RHRHRHHCQNRLSGVAGCLPLPRPRDGARSPQPLPWKPGLPSLCVASGLRT 173
             R G H  R    H   ++ S      P PR RD A +  P P   G  S       R+
Sbjct: 318 GQRSGAHGGRPGSAHSPPDKPSS-----PSPRVRDKAAAAAPTPPARGKES----PSPRS 368

Query: 174 APDASAPGRAAKTRSSGAR 192
           AP  S+ GR  +      R
Sbjct: 369 AP--SSQGRGGRAAGGAGR 385



 Score = 32.0 bits (71), Expect = 0.34
 Identities = 48/200 (24%), Positives = 70/200 (35%), Gaps = 25/200 (12%)

Query: 4   PMPLEPPATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGA 63
           P P   P++    R G+  G GA  RR   +++        + ++      G R  R   
Sbjct: 364 PSPRSAPSSQG--RGGRAAG-GAGRRRRRRRRRRRSRSSASAPRRR-----GRRRPRPAP 415

Query: 64  AGQGAQGWAAARRESRAAGGR------LECLGLRAGAGRGGGEEEEPARAPPRRGGASRG 117
               ++  + AR  S +  GR       E    R   G G   +E P RA P     S G
Sbjct: 416 PRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPG 475

Query: 118 RVGRHRHRHRHHCQNRLSGVAGCLPLPRPRDGARSP-----QPLPWKPGLPSLCVASGLR 172
             GR R        +R  G     P PR    +RSP     +    +P  PS   +    
Sbjct: 476 AHGR-RGGPEGKSSSRSPG-----PHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKP 529

Query: 173 TAPDASAPGRAAKTRSSGAR 192
            + D    GRA  + +   R
Sbjct: 530 LSRDKDGEGRARHSEAEATR 549


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 47/183 (25%), Positives = 58/183 (31%), Gaps = 32/183 (17%)

Query: 10  PATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQGAQ 69
           P  HHH      + L   +   H+         G       + G GA  G  G  G G  
Sbjct: 97  PLAHHHHHHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGG 156

Query: 70  GWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVGRHRHRHRH- 128
           G           GG     G   G G GGG            GG   G +G   H H H 
Sbjct: 157 G--------GPGGGP----GGGGGGGPGGG-----------GGGPGGGLLGGSAHPHPHM 193

Query: 129 HCQNRLSGVAGCLPLPRPRDGARSPQPLPWKPGLPSLCVASGLRTAPDASAPGRAAKTRS 188
           H    LS  A    +         P  LP  PGL +     G   A  A+A G+ A   +
Sbjct: 194 HSLGHLSHPAAAAAM-------NMPSGLP-HPGLVAAAAHHGAAAAAAAAAAGQVAAASA 245

Query: 189 SGA 191
           + A
Sbjct: 246 AAA 248


>gi|169171347 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1128

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 39/127 (30%), Positives = 50/127 (39%), Gaps = 11/127 (8%)

Query: 9   PPATHHHMRP-GQGEGLGADERRHHVQQQH-------EGHEEGGSQQQHRSAGPGARSGR 60
           P ++  H+ P  Q +G G  E R    ++         G   GG     +  G  A +G 
Sbjct: 404 PLSSEGHLLPLVQRDGGGLAEHRGREGEEGVRAGGGGTGEVRGGGSPGRQPVGRAAVTGE 463

Query: 61  AGA--AGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGR 118
           AGA  AG+GAQ       E R A G  +  G R G  +     E   RA   RGG   G 
Sbjct: 464 AGAGAAGRGAQSVRGPGVERRVAEGAQQ-FGPRVGLRQHAERVERAQRAAEGRGGGGGGG 522

Query: 119 VGRHRHR 125
            G   HR
Sbjct: 523 CGAQAHR 529


>gi|239753418 PREDICTED: similar to hCG2012845 [Homo sapiens]
          Length = 195

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 36/103 (34%), Positives = 45/103 (43%), Gaps = 21/103 (20%)

Query: 9   PPATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQGA 68
           P A HH  RP       A  RRHH QQQ +   E  ++++ R  G G R     A G   
Sbjct: 101 PAAAHHPTRPA------APCRRHH-QQQQQDQAE--ARRRERCGGSGVRV----APGGSR 147

Query: 69  QGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRR 111
           +G    R  +RA G ++         G G G E   AR PPRR
Sbjct: 148 RGRHGRRGAARAGGTQVR--------GGGPGPELVAARCPPRR 182


>gi|169172209 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 801

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 39/127 (30%), Positives = 50/127 (39%), Gaps = 11/127 (8%)

Query: 9   PPATHHHMRP-GQGEGLGADERRHHVQQQH-------EGHEEGGSQQQHRSAGPGARSGR 60
           P ++  H+ P  Q +G G  E R    ++         G   GG     +  G  A +G 
Sbjct: 77  PLSSEGHLLPLVQRDGGGLAEHRGREGEEGVRAGGGGTGEVRGGGSPGRQPVGRAAVTGE 136

Query: 61  AGA--AGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGR 118
           AGA  AG+GAQ       E R A G  +  G R G  +     E   RA   RGG   G 
Sbjct: 137 AGAGAAGRGAQSVRGPGVERRVAEGAQQ-FGPRVGLRQHAERVERAQRAAEGRGGGGGGG 195

Query: 119 VGRHRHR 125
            G   HR
Sbjct: 196 CGAQAHR 202


>gi|169170953 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 801

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 39/127 (30%), Positives = 50/127 (39%), Gaps = 11/127 (8%)

Query: 9   PPATHHHMRP-GQGEGLGADERRHHVQQQH-------EGHEEGGSQQQHRSAGPGARSGR 60
           P ++  H+ P  Q +G G  E R    ++         G   GG     +  G  A +G 
Sbjct: 77  PLSSEGHLLPLVQRDGGGLAEHRGREGEEGVRAGGGGTGEVRGGGSPGRQPVGRAAVTGE 136

Query: 61  AGA--AGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGR 118
           AGA  AG+GAQ       E R A G  +  G R G  +     E   RA   RGG   G 
Sbjct: 137 AGAGAAGRGAQSVRGPGVERRVAEGAQQ-FGPRVGLRQHAERVERAQRAAEGRGGGGGGG 195

Query: 119 VGRHRHR 125
            G   HR
Sbjct: 196 CGAQAHR 202


>gi|239743069 PREDICTED: hypothetical protein XP_002342750 [Homo
           sapiens]
          Length = 231

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 51/143 (35%), Positives = 55/143 (38%), Gaps = 16/143 (11%)

Query: 54  PGARSGRAGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGG 113
           PG   G  G  G GAQ WAA RR  R  G     L    G  R         R   RRG 
Sbjct: 82  PGGSGG--GGGGCGAQHWAAGRRAQREQGAGAAVLA-DFGHVRAAPSGLRRRRLQRRRG- 137

Query: 114 ASRGRVGRHRHRHRHHCQNRLSGVAGCLPLPRPRDGARSPQPLPWKPGLPSLCVAS-GLR 172
              GR GR   R R    +R +G    LP  R    AR P P    P +  +  AS GL 
Sbjct: 138 ---GRGGRGAGRARKPGPDR-AGAERSLPAHRAPRLARPPVP----PSVAHVARASAGLG 189

Query: 173 TAPDASAPGRAAKTRSSGARMAS 195
             P    PG  A  R S AR  S
Sbjct: 190 ARP---VPGGPAGPRESWARRTS 209


>gi|239508753 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 801

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 39/127 (30%), Positives = 50/127 (39%), Gaps = 11/127 (8%)

Query: 9   PPATHHHMRP-GQGEGLGADERRHHVQQQH-------EGHEEGGSQQQHRSAGPGARSGR 60
           P ++  H+ P  Q +G G  E R    ++         G   GG     +  G  A +G 
Sbjct: 77  PLSSEGHLLPLVQRDGGGLAEHRGREGEEGVRAGGGGTGEVRGGGSPGRQPVGRAAVTGE 136

Query: 61  AGA--AGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGR 118
           AGA  AG+GAQ       E R A G  +  G R G  +     E   RA   RGG   G 
Sbjct: 137 AGAGAAGRGAQSVRGPGVERRVAEGAQQ-FGPRVGLRQHAERVERAQRAAEGRGGGGGGG 195

Query: 119 VGRHRHR 125
            G   HR
Sbjct: 196 CGAQAHR 202


>gi|239508715 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 231

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 51/143 (35%), Positives = 55/143 (38%), Gaps = 16/143 (11%)

Query: 54  PGARSGRAGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGG 113
           PG   G  G  G GAQ WAA RR  R  G     L    G  R         R   RRG 
Sbjct: 82  PGGSGG--GGGGCGAQHWAAGRRAQREQGAGAAVLA-DFGHVRAAPSGLRRRRLQRRRG- 137

Query: 114 ASRGRVGRHRHRHRHHCQNRLSGVAGCLPLPRPRDGARSPQPLPWKPGLPSLCVAS-GLR 172
              GR GR   R R    +R +G    LP  R    AR P P    P +  +  AS GL 
Sbjct: 138 ---GRGGRGAGRARKPGPDR-AGAERSLPAHRAPRLARPPVP----PSVAHVARASAGLG 189

Query: 173 TAPDASAPGRAAKTRSSGARMAS 195
             P    PG  A  R S AR  S
Sbjct: 190 ARP---VPGGPAGPRESWARRTS 209


>gi|239752810 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 207

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 54/187 (28%), Positives = 68/187 (36%), Gaps = 34/187 (18%)

Query: 5   MPLEPPATHHHM------------RPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSA 52
           MPL+PP T H +            +PG+     +  RR  +  +          Q  +S 
Sbjct: 19  MPLKPPTTWHTVGTQVIAEAVPSTKPGE-----STYRRGAIAHERLSTPRPTQVQAKKSV 73

Query: 53  GPGARSGRAGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGG------EEEEP-A 105
           G    SGRAGA+G G      A+      GG  E    R  A RG G      +E+ P A
Sbjct: 74  G----SGRAGASGLG-----GAKAPQEGCGGPPELTARRGAALRGPGLEEVEADEQHPLA 124

Query: 106 RAPPRRGGASRGRVGRHRHRHRHHCQNRLSGVAGCLPLPRPRDGARSPQPLPWKPGLPSL 165
            APPR     R          R      L G AGC     PR+     QP    PG+   
Sbjct: 125 AAPPRVVVERRAAAVLALRDDRFVVLVVLHG-AGCGASLPPREDVPQQQPHTQAPGVQPG 183

Query: 166 CVASGLR 172
             AS  R
Sbjct: 184 LPASNCR 190


>gi|157676331 hyaluronan binding protein 4 [Homo sapiens]
          Length = 413

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 39/147 (26%), Positives = 56/147 (38%), Gaps = 18/147 (12%)

Query: 28  ERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQGAQGWAAARRESRAAGGRLEC 87
           ERR   Q Q +  +E  +     +AG G R GR+ A   G +  A  RRES+     L  
Sbjct: 46  ERRRQQQLQRKRRDEAAA-----AAGAGPRGGRSPAGASGHRAGAGGRRESQKERKSLPA 100

Query: 88  LGLRAGAGRGGGEEEEPARAPPRRG-----GASRGRVG--------RHRHRHRHHCQNRL 134
              +     GGG +    +  PRRG       SRG  G         +R    +  + + 
Sbjct: 101 PVAQRPDSPGGGLQAPGQKRTPRRGEQQGWNDSRGPEGMLERAERRSYREYRPYETERQA 160

Query: 135 SGVAGCLPLPRPRDGARSPQPLPWKPG 161
              A   P  +P D     +PL  + G
Sbjct: 161 DFTAEKFPDEKPGDRFDRDRPLRGRGG 187


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 35/122 (28%), Positives = 39/122 (31%), Gaps = 11/122 (9%)

Query: 14  HHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSG---RAGAAGQGAQG 70
           H    G G G+G+  R H       G   GG  + H   G G   G   R      G  G
Sbjct: 767 HRPHEGPGGGMGSGHRPHEGPGGSMG--GGGGHRPHEGPGGGISGGSGHRPHEGPGGGMG 824

Query: 71  WAAARRESRAAGGRLECLG---LRAGAGRGGGEEEEPARAPPRRGGASRGRVGRHRHRHR 127
                R     GG +   G      G G GG     P   P  RG   R   G   H HR
Sbjct: 825 AGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHR---GPPPHEHR 881

Query: 128 HH 129
            H
Sbjct: 882 GH 883



 Score = 35.4 bits (80), Expect = 0.031
 Identities = 36/124 (29%), Positives = 40/124 (32%), Gaps = 14/124 (11%)

Query: 18  PGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQG-AQGWAAARR 76
           PG G   G   R H       G+  G   + H   G G  SG     G G + G     R
Sbjct: 741 PGGGMVGGGGHRPHEGPGGGMGNSSG--HRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHR 798

Query: 77  ESRAAGGRLEC-LGLRAGAGRGGGEEEEPARAPPRRGGASRGRVGRHR----------HR 125
                GG +    G R   G GGG        P    G S G  G HR          H 
Sbjct: 799 PHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHG 858

Query: 126 HRHH 129
           HR H
Sbjct: 859 HRPH 862



 Score = 31.2 bits (69), Expect = 0.58
 Identities = 35/118 (29%), Positives = 37/118 (31%), Gaps = 21/118 (17%)

Query: 16  MRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGP--GARSGRAGAA--------G 65
           MR G G G G           H G    G  +      P  GAR GR+G          G
Sbjct: 692 MRGGPGPGPGP---------YHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPG 742

Query: 66  QGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVGRHR 123
            G  G    R      GG     G R   G GGG        P    G S G  G HR
Sbjct: 743 GGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGS--GHRPHEGPGGSMGGGGGHR 798



 Score = 27.7 bits (60), Expect = 6.5
 Identities = 33/115 (28%), Positives = 38/115 (33%), Gaps = 17/115 (14%)

Query: 15  HMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGA----AGQGAQG 70
           H  PG G   G+  R H  +    G   GG  + H   GPG   G +G      G G  G
Sbjct: 800 HEGPGGGISGGSGHRPH--EGPGGGMGAGGGHRPHE--GPGGSMGGSGGHRPHEGPGHGG 855

Query: 71  WAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPAR-APPRRGGASRGRVGRHRH 124
               R          +  G R    RG    E      P   GG  RG  G H H
Sbjct: 856 PHGHRPH--------DVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGHSH 902


>gi|239754489 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 228

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 48/135 (35%), Positives = 52/135 (38%), Gaps = 14/135 (10%)

Query: 62  GAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVGR 121
           G  G GAQ WAA RR  R  G     L    G  R         R   RRG    GR GR
Sbjct: 85  GGGGCGAQHWAAGRRAQREQGAGAAVLA-DFGHVRAAPSGLRRRRLQRRRG----GRGGR 139

Query: 122 HRHRHRHHCQNRLSGVAGCLPLPRPRDGARSPQPLPWKPGLPSLCVAS-GLRTAPDASAP 180
              R R    +R +G    LP  R    AR P P    P +  +  AS GL   P    P
Sbjct: 140 GAGRARKPGPDR-AGAERSLPAHRAPRLARPPVP----PSVAHVARASAGLGARP---VP 191

Query: 181 GRAAKTRSSGARMAS 195
           G  A  R S AR  S
Sbjct: 192 GGPAGPRESWARRTS 206


>gi|239754138 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 274

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 48/181 (26%), Positives = 61/181 (33%), Gaps = 19/181 (10%)

Query: 4   PMPLEPPATHH----HMRPGQGEGLGADERR--------HHVQQQHEGHEEGGSQQQHRS 51
           P P  PPA  H     +  G    L A   R           ++  +G   G   +    
Sbjct: 71  PPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAP 130

Query: 52  AGPGARSGRAGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRR 111
           A P AR+ RA +          +R  SR+   RL   G R  A +     E       +R
Sbjct: 131 ASPRARAARAISNQSSPPPPPPSRARSRSL--RLSAPGSRHDAEKAS---ERNRLRRKKR 185

Query: 112 GGASRGRVGRHRHRHRHHCQNRLSGVAGCLPLPRPRDGAR--SPQPLPWKPGLPSLCVAS 169
               RG  G   H H   C  R+      L   RP D  R  SP  L W P L    + S
Sbjct: 186 LVLGRGGGGECAHAHEWECARRMRRGCRTLTARRPLDSGRGLSPLILAWVPALSGPALNS 245

Query: 170 G 170
           G
Sbjct: 246 G 246


>gi|239742631 PREDICTED: hypothetical protein XP_002342600 [Homo
           sapiens]
          Length = 274

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 48/181 (26%), Positives = 61/181 (33%), Gaps = 19/181 (10%)

Query: 4   PMPLEPPATHH----HMRPGQGEGLGADERR--------HHVQQQHEGHEEGGSQQQHRS 51
           P P  PPA  H     +  G    L A   R           ++  +G   G   +    
Sbjct: 71  PPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAP 130

Query: 52  AGPGARSGRAGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRR 111
           A P AR+ RA +          +R  SR+   RL   G R  A +     E       +R
Sbjct: 131 ASPRARAARAISNQSSPPPPPPSRARSRSL--RLSAPGSRHDAEKAS---ERNRLRRKKR 185

Query: 112 GGASRGRVGRHRHRHRHHCQNRLSGVAGCLPLPRPRDGAR--SPQPLPWKPGLPSLCVAS 169
               RG  G   H H   C  R+      L   RP D  R  SP  L W P L    + S
Sbjct: 186 LVLGRGGGGECAHAHEWECARRMRRGCRTLTARRPLDSGRGLSPLILAWVPALSGPALNS 245

Query: 170 G 170
           G
Sbjct: 246 G 246


>gi|124107614 PR domain containing 13 [Homo sapiens]
          Length = 707

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 42/135 (31%), Positives = 48/135 (35%), Gaps = 27/135 (20%)

Query: 50  RSAGPGARSGRAGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPP 109
           RSA   A   RA AA  G       R ES +  G    LG   G GR  G        P 
Sbjct: 292 RSAFKPAGLARAAAAAHGDP----YREESSSKQGAGLALGRLLGGGRACGR-------PG 340

Query: 110 RRGGASRGRVGRHRHRHRHHCQNRLSGVAGCLPLPRPRDGARSPQPLPWKPGLPSLCVAS 169
               ++ G  G H H H HH  +    +AG  P P P             PGLP    + 
Sbjct: 341 SGENSAAGGAGHHHHHHAHHHHHPKCLLAGDPPPPPP-------------PGLP---CSG 384

Query: 170 GLRTAPDASAPGRAA 184
            LR  P  S P   A
Sbjct: 385 ALRGFPLLSVPPEEA 399


>gi|239750468 PREDICTED: similar to Os05g0242100 [Homo sapiens]
          Length = 758

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 33/99 (33%), Positives = 42/99 (42%), Gaps = 6/99 (6%)

Query: 22  EGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQGAQGWAAARRESRAA 81
           +G     RR   Q++H         Q+H  +G  A    AGAA Q A G+   RR  R A
Sbjct: 47  QGSAPGRRRGRRQRRHRRGLRARRPQRHGGSGTAAH---AGAARQVASGFMPHRRRRRTA 103

Query: 82  GGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVG 120
            G+    G R    +G G     A +   RGGA  GR G
Sbjct: 104 PGQPWASGFRR---QGRGLSGPGAGSGRGRGGALIGRAG 139


>gi|150378549 tangerin [Homo sapiens]
          Length = 1523

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 48/166 (28%), Positives = 58/166 (34%), Gaps = 26/166 (15%)

Query: 35   QQHEGHEEGGSQQQHRSA------GPGARSGRAGAAGQGAQGWAAARRESRAAGGRLECL 88
            Q+  GH   G Q+   +A       PG  S  A A      G A A RESR A    E L
Sbjct: 1180 QRLRGHGAEGPQEPKEAADRADGAAPGVASRNAVAGRASKDGGAEAPRESRPAEVPAEGL 1239

Query: 89   GLRAGAGRGGG-------EEEEPARAPPRRGGASRGRV------GRHRHRHRHHCQNRLS 135
               AGA  GGG          EP   PP R   S   V       + R R R+     + 
Sbjct: 1240 VNGAGAPGGGGVRLRRPSVNGEPGSVPPPRAHGSFSHVRDADLLKKRRSRLRNSSSFSMD 1299

Query: 136  GV-AGCLPLPRPRDGARSPQPLPWKPGLPSLCVASGLRTAPDASAP 180
               AG +        A  P P P  P       A+  +  P  S+P
Sbjct: 1300 DPDAGAMGAAAAEGQAPDPSPAPGPP------TAADSQQPPGGSSP 1339


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 32/140 (22%), Positives = 52/140 (37%), Gaps = 22/140 (15%)

Query: 10   PATHHHMRPGQGEGLGADER--RHHVQQQHEGHEEGGSQQQHRSAG--------PGARSG 59
            P +HH  R G G    +  +   HH +    G      +Q   SAG          A S 
Sbjct: 3578 PTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSS 3637

Query: 60   RAGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRV 119
            R    G G    ++A R+S          G R  +G    + E  +     +  ++ G+ 
Sbjct: 3638 RHSGIGHGQA--SSAVRDS----------GHRGSSGSQASDSEGHSEDSDTQSVSAHGQA 3685

Query: 120  GRHRHRHRHHCQNRLSGVAG 139
            G H+  H+   + R +G +G
Sbjct: 3686 GPHQQSHQESTRGRSAGRSG 3705



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 32/140 (22%), Positives = 52/140 (37%), Gaps = 22/140 (15%)

Query: 10   PATHHHMRPGQGEGLGADER--RHHVQQQHEGHEEGGSQQQHRSAG--------PGARSG 59
            P +HH  R G G    +  +   HH +    G      +Q   SAG          A S 
Sbjct: 2282 PRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSS 2341

Query: 60   RAGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRV 119
            R    G G    ++A R+S          G R  +G    + E  +     +  ++ G+ 
Sbjct: 2342 RHSGIGHGQA--SSAVRDS----------GHRGSSGSQASDSEGHSEDSDTQSVSAHGQA 2389

Query: 120  GRHRHRHRHHCQNRLSGVAG 139
            G H+  H+   + R +G +G
Sbjct: 2390 GPHQQSHQESTRGRSAGRSG 2409



 Score = 35.0 bits (79), Expect = 0.040
 Identities = 30/127 (23%), Positives = 41/127 (32%), Gaps = 8/127 (6%)

Query: 17  RPGQGEGLGADERRHHVQQQHE--------GHEEGGSQQQHRSAGPGARSGRAGAAGQGA 68
           R G G    AD  RH    + +        GH      Q   S G    S     +G G 
Sbjct: 383 RHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGK 442

Query: 69  QGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVGRHRHRHRH 128
            G      +    G   E  G    +       E+P  A  R G ++ GR G H  + R 
Sbjct: 443 AGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARD 502

Query: 129 HCQNRLS 135
             ++  S
Sbjct: 503 SSRHSAS 509



 Score = 35.0 bits (79), Expect = 0.040
 Identities = 30/135 (22%), Positives = 47/135 (34%), Gaps = 23/135 (17%)

Query: 10  PATHHHMRPGQGEGLGADER--RHHVQQQHEGHEEGGSQQQHRSAG---------PGARS 58
           P +HH  R G G    +  +    H Q    G      +Q   SAG           A S
Sbjct: 660 PRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADS 719

Query: 59  GRAGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGR 118
            R    G G    ++A R+S          G R  +G    + E  +     +  +  G+
Sbjct: 720 SRHSGTGHGQA--SSAVRDS----------GHRGSSGSQATDSEGHSEDSDTQSVSGHGQ 767

Query: 119 VGRHRHRHRHHCQNR 133
            G H+  H+   ++R
Sbjct: 768 AGHHQQSHQESARDR 782



 Score = 34.3 bits (77), Expect = 0.069
 Identities = 35/140 (25%), Positives = 53/140 (37%), Gaps = 22/140 (15%)

Query: 10   PATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSA--GPGARSG-------- 59
            P +HH  R G G    AD  R    +  E    G +   H  A   PG R G        
Sbjct: 3254 PRSHHEDRAGHGH--SADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSAD 3311

Query: 60   RAGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRV 119
             +  +G      ++A R+SR  G      G +A    G  EE +       +  +  G+ 
Sbjct: 3312 SSRHSGIPRGQASSAVRDSRHWGSS----GSQASDSEGHSEESD------TQSVSGHGQA 3361

Query: 120  GRHRHRHRHHCQNRLSGVAG 139
            G H+  H+   ++R  G +G
Sbjct: 3362 GPHQQSHQESARDRSGGRSG 3381



 Score = 33.9 bits (76), Expect = 0.090
 Identities = 37/141 (26%), Positives = 49/141 (34%), Gaps = 32/141 (22%)

Query: 35   QQHEGHEEGGS-QQQHRSAGPGARSGRAGAAGQGAQGWAAARRESRAAGGRLECLGLRAG 93
            Q   GH + G  QQ H+ +      GR+G +G       +   +S +A GR      R  
Sbjct: 3353 QSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLY-QVSTHEQSESAHGR-----TRTS 3406

Query: 94   AGRGGGEEEEPARAPPRR--------------GGASRGRVGRH--------RHRHRHHCQ 131
             GR  G   E AR   R               G + RGR G H         H   HH  
Sbjct: 3407 TGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSH 3466

Query: 132  NRLSGVAGCLPLPRPRDGARS 152
                G +      R + G+RS
Sbjct: 3467 TTSQGRSDA---SRGQSGSRS 3484



 Score = 33.5 bits (75), Expect = 0.12
 Identities = 34/134 (25%), Positives = 49/134 (36%), Gaps = 10/134 (7%)

Query: 10   PATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQGAQ 69
            P +HH  R G G    AD  R    Q    H E  S  Q  S+   ARS      G   Q
Sbjct: 985  PRSHHEDRAGHGH--SADSSR----QSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQ 1038

Query: 70   GWAAARRES----RAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVGRHRHR 125
              A + R S    R A   +   G    +G    + E  +     +  +  G+ G H+  
Sbjct: 1039 QSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQS 1098

Query: 126  HRHHCQNRLSGVAG 139
            H+   ++   G +G
Sbjct: 1099 HQESARDWSGGRSG 1112



 Score = 33.5 bits (75), Expect = 0.12
 Identities = 33/135 (24%), Positives = 52/135 (38%), Gaps = 11/135 (8%)

Query: 10   PATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQGAQ 69
            P +HH  R G G    AD  R    Q    H E  S+ Q  S+   ARS      G   Q
Sbjct: 1957 PGSHHEDRAGHGH--SADSSR----QSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQ 2010

Query: 70   GWAA-ARRESRAAGGRLECL----GLRAGAGRGGGEEEEPARAPPRRGGASRGRVGRHRH 124
              +A + R S    G+        G R  +G    + E  +     +  +++G+ G H+ 
Sbjct: 2011 LQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQ 2070

Query: 125  RHRHHCQNRLSGVAG 139
             H+   + +    +G
Sbjct: 2071 SHKESARGQSGESSG 2085



 Score = 32.7 bits (73), Expect = 0.20
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 7/85 (8%)

Query: 35   QQHEGH-EEGGSQQQHRSAGPGARSGRAGAAGQGAQGWAAARRESRAAGGRLECLGLRAG 93
            Q   GH ++G  QQ H+ +      GR+G +G       +   +S +A GR      R  
Sbjct: 1084 QSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIY-QVSTHEQSESAHGR-----TRTS 1137

Query: 94   AGRGGGEEEEPARAPPRRGGASRGR 118
             GR  G   E AR   R   +  G+
Sbjct: 1138 TGRRQGSHHEQARDSSRHSASQEGQ 1162



 Score = 31.6 bits (70), Expect = 0.45
 Identities = 31/128 (24%), Positives = 45/128 (35%), Gaps = 10/128 (7%)

Query: 10  PATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQGAQ 69
           P +H   R   G    AD  R    Q    H E  S+ Q  S+   ARS      G G Q
Sbjct: 336 PRSHDEDRASHGHS--ADSSR----QSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQ 389

Query: 70  GWAAARRESRAAGGRLECL----GLRAGAGRGGGEEEEPARAPPRRGGASRGRVGRHRHR 125
             A + R S    G+        G R  +G    + E  +     +  +  G+ G  +  
Sbjct: 390 QSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQS 449

Query: 126 HRHHCQNR 133
           H+   + R
Sbjct: 450 HQESTRGR 457



 Score = 30.8 bits (68), Expect = 0.76
 Identities = 33/128 (25%), Positives = 45/128 (35%), Gaps = 22/128 (17%)

Query: 13   HHHMRP--------GQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAA 64
            H H  P        GQ     A  +  + +Q  +G    GS  +H      A S R    
Sbjct: 1519 HSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGS--RHHEPSTRAGSSRHSQV 1576

Query: 65   GQGAQGWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVGRHRH 124
            GQG    +A  + SR  G  +     +     G  E+ E      R   ASR   G  R 
Sbjct: 1577 GQGE---SAGSKTSRRQGSSVS----QDRDSEGHSEDSE-----RRSESASRNHYGSARE 1624

Query: 125  RHRHHCQN 132
            + RH  +N
Sbjct: 1625 QSRHGSRN 1632



 Score = 30.8 bits (68), Expect = 0.76
 Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 10/80 (12%)

Query: 41   EEGGSQQQHRSAGPGARSGRAGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGG-- 98
            + G  QQ H+ +  G  +GR+G +G       +   +S +A G       RAG   GG  
Sbjct: 3684 QAGPHQQSHQESTRGRSAGRSGRSGSFLY-QVSTHEQSESAHG-------RAGPSTGGRQ 3735

Query: 99   GEEEEPARAPPRRGGASRGR 118
            G   E AR   R   +  G+
Sbjct: 3736 GSRHEQARDSSRHSASQEGQ 3755



 Score = 30.0 bits (66), Expect = 1.3
 Identities = 33/127 (25%), Positives = 45/127 (35%), Gaps = 18/127 (14%)

Query: 10   PATHHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQGAQ 69
            P    H    +G   G   R      Q   HE+  S+  H  AGP +  GR G+  + A+
Sbjct: 3687 PHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQ--SESAHGRAGP-STGGRQGSRHEQAR 3743

Query: 70   GWAAARRESRAAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASRGRVGRHRHRHRHH 129
                + R S +  G+    G   G+ RGG           R+G      V R  H   HH
Sbjct: 3744 D---SSRHSASQEGQDTIRG-HPGSRRGG-----------RQGSYHEQSVDRSGHSGSHH 3788

Query: 130  CQNRLSG 136
                  G
Sbjct: 3789 SHTTSQG 3795



 Score = 29.6 bits (65), Expect = 1.7
 Identities = 23/86 (26%), Positives = 35/86 (40%), Gaps = 10/86 (11%)

Query: 41   EEGGSQQQHRSAGPGARSGRAGAAGQGAQGWAAARRESRAAGGRLECLGLRAGAGRGG-- 98
            + G  QQ H+ +  G  +GR+G +G       +   +S +A G       R G   GG  
Sbjct: 2388 QAGPHQQSHQESTRGRSAGRSGRSGSFLY-QVSTHEQSESAHG-------RTGTSTGGRQ 2439

Query: 99   GEEEEPARAPPRRGGASRGRVGRHRH 124
            G   + AR   R   +  G+   H H
Sbjct: 2440 GSHHKQARDSSRHSTSQEGQDTIHGH 2465



 Score = 28.9 bits (63), Expect = 2.9
 Identities = 45/173 (26%), Positives = 59/173 (34%), Gaps = 40/173 (23%)

Query: 17   RPGQGEGLGADERRHHVQQQ-------HEGHEEGGSQQQHRSAGPGARSGRAGA------ 63
            R G       D  RH   Q+       H G   GG Q  H       RSG +G+      
Sbjct: 1141 RQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVD-RSGHSGSHHSHTT 1199

Query: 64   ------AGQGAQGWAAARRE----------SRAAGGRLECLGLRAGAGRGG--GEEEEPA 105
                  A  G  G  +A R+          SR +G R       A + R    G+E+   
Sbjct: 1200 SQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSG 1259

Query: 106  RAPPRRGGASRGRVGRHRHRHRHHCQN-RLSGVAG----CLPLPRPRDGARSP 153
                R  G+S   V +     RH   + RLSG A          + RDG+R P
Sbjct: 1260 SRTSRHQGSS---VSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHP 1309



 Score = 28.1 bits (61), Expect = 4.9
 Identities = 23/87 (26%), Positives = 33/87 (37%), Gaps = 11/87 (12%)

Query: 35  QQHEGHEEGGSQQQ-HRSAGPGARSGRAGAAGQGAQGWAAARRESRAAGGRLECLGLRAG 93
           Q   GH + G +QQ H+ +  G    R+G +G      +   +   A G        R G
Sbjct: 435 QSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHG--------RTG 486

Query: 94  AGRGG--GEEEEPARAPPRRGGASRGR 118
              GG  G   E AR   R   +  G+
Sbjct: 487 TSTGGRQGSHHEQARDSSRHSASQEGQ 513



 Score = 27.7 bits (60), Expect = 6.5
 Identities = 26/143 (18%), Positives = 46/143 (32%), Gaps = 16/143 (11%)

Query: 13   HHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQGAQGWA 72
            HH     Q        R H   +   GH    S+Q        +  G+A ++ + A+  A
Sbjct: 2591 HHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSA 2650

Query: 73   AARRESR----------------AAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASR 116
              R  S                  A   +   G R  +G    + E  +     +  ++ 
Sbjct: 2651 GERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAH 2710

Query: 117  GRVGRHRHRHRHHCQNRLSGVAG 139
            G+ G H+  H+   + R    +G
Sbjct: 2711 GQAGSHQQSHQESARGRSGETSG 2733



 Score = 27.7 bits (60), Expect = 6.5
 Identities = 26/143 (18%), Positives = 46/143 (32%), Gaps = 16/143 (11%)

Query: 13   HHHMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGAAGQGAQGWA 72
            HH     Q        R H   +   GH    S+Q        +  G+A ++ + A+  A
Sbjct: 2915 HHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSA 2974

Query: 73   AARRESR----------------AAGGRLECLGLRAGAGRGGGEEEEPARAPPRRGGASR 116
              R  S                  A   +   G R  +G    + E  +     +  ++ 
Sbjct: 2975 GERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAH 3034

Query: 117  GRVGRHRHRHRHHCQNRLSGVAG 139
            G+ G H+  H+   + R    +G
Sbjct: 3035 GQAGSHQQSHQESARGRSGETSG 3057



 Score = 27.3 bits (59), Expect = 8.4
 Identities = 37/151 (24%), Positives = 48/151 (31%), Gaps = 41/151 (27%)

Query: 15   HMRPGQGEGLGADERRHHVQQQHEGHEEGGSQQQHRSAGPGARSGRAGA---------AG 65
            H  P +G   G+ + +   +  H G     +  Q RS     +SG   A         +G
Sbjct: 2141 HPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSG 2200

Query: 66   QG----------AQGWAAARRESRAAGGRLECLGLRAGAGRGG---------GEEEEPAR 106
             G          A  WA + R S    G  +  G R    RG          G  E+  R
Sbjct: 2201 DGSRHSGSHHHEASSWADSSRHSLVGQG--QSSGPRTSRPRGSSVSQDSDSEGHSEDSER 2258

Query: 107  APPRRGGASRGRVGR--------HRHRHRHH 129
               R G ASR   G          RH   HH
Sbjct: 2259 ---RSGSASRNHHGSAQEQSRDGSRHPRSHH 2286


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,759,959
Number of Sequences: 37866
Number of extensions: 675911
Number of successful extensions: 6643
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 154
Number of HSP's successfully gapped in prelim test: 664
Number of HSP's that attempted gapping in prelim test: 5217
Number of HSP's gapped (non-prelim): 1787
length of query: 195
length of database: 18,247,518
effective HSP length: 97
effective length of query: 98
effective length of database: 14,574,516
effective search space: 1428302568
effective search space used: 1428302568
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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