BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo sapiens] (4485 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 8953 0.0 gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 8947 0.0 gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 8792 0.0 gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 5712 0.0 gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] 5294 0.0 gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 2287 0.0 gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 2162 0.0 gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] 1989 0.0 gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] 1981 0.0 gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 1946 0.0 gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 1921 0.0 gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] 1896 0.0 gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 1893 0.0 gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 1344 0.0 gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap... 1213 0.0 gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] 1160 0.0 gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 954 0.0 gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H... 701 0.0 gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 158 1e-37 gi|71061468 centromere protein E [Homo sapiens] 48 3e-04 gi|124249396 coiled-coil domain containing 30 [Homo sapiens] 46 0.001 gi|34577114 cytomatrix protein p110 [Homo sapiens] 44 0.004 gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 42 0.014 gi|109255234 centrosomal protein 290kDa [Homo sapiens] 42 0.018 gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 42 0.018 gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 42 0.018 gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 41 0.023 gi|4502395 beclin 1 [Homo sapiens] 41 0.031 gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 39 0.089 gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 39 0.12 >gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo sapiens] Length = 4485 Score = 8953 bits (23232), Expect = 0.0 Identities = 4485/4485 (100%), Positives = 4485/4485 (100%) Query: 1 MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60 MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG Sbjct: 1 MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60 Query: 61 MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120 MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL Sbjct: 61 MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120 Query: 121 LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180 LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER Sbjct: 121 LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180 Query: 181 IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC 240 IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC Sbjct: 181 IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC 240 Query: 241 IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300 IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME Sbjct: 241 IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300 Query: 301 QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360 QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK Sbjct: 301 QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360 Query: 361 GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420 GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF Sbjct: 361 GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420 Query: 421 FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480 FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD Sbjct: 421 FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480 Query: 481 PGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAE 540 PGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAE Sbjct: 481 PGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAE 540 Query: 541 VAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLE 600 VAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLE Sbjct: 541 VAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLE 600 Query: 601 VSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPL 660 VSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPL Sbjct: 601 VSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPL 660 Query: 661 ILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELI 720 ILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELI Sbjct: 661 ILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELI 720 Query: 721 VGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQN 780 VGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQN Sbjct: 721 VGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQN 780 Query: 781 RMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQ 840 RMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQ Sbjct: 781 RMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQ 840 Query: 841 AMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFE 900 AMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFE Sbjct: 841 AMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFE 900 Query: 901 IRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMNYKMDLEDNT 960 IRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMNYKMDLEDNT Sbjct: 901 IRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMNYKMDLEDNT 960 Query: 961 DLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTW 1020 DLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTW Sbjct: 961 DLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTW 1020 Query: 1021 TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW 1080 TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW Sbjct: 1021 TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW 1080 Query: 1081 GFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATD 1140 GFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATD Sbjct: 1081 GFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATD 1140 Query: 1141 NMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSIL 1200 NMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSIL Sbjct: 1141 NMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSIL 1200 Query: 1201 RRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKVFLLKGIMEALSKSGGLFEVPVP 1260 RRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKVFLLKGIMEALSKSGGLFEVPVP Sbjct: 1201 RRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKVFLLKGIMEALSKSGGLFEVPVP 1260 Query: 1261 DYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLD 1320 DYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLD Sbjct: 1261 DYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLD 1320 Query: 1321 KEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLAD 1380 KEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLAD Sbjct: 1321 KEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLAD 1380 Query: 1381 LLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEV 1440 LLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEV Sbjct: 1381 LLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEV 1440 Query: 1441 LVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFI 1500 LVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFI Sbjct: 1441 LVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFI 1500 Query: 1501 GSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICE 1560 GSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICE Sbjct: 1501 GSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICE 1560 Query: 1561 KALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASD 1620 KALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASD Sbjct: 1561 KALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASD 1620 Query: 1621 KPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPR 1680 KPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPR Sbjct: 1621 KPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPR 1680 Query: 1681 EQWILDYPAQIWWTTEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRM 1740 EQWILDYPAQIWWTTEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRM Sbjct: 1681 EQWILDYPAQIWWTTEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRM 1740 Query: 1741 KIMTICTIDVHARDVVAKMIVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYL 1800 KIMTICTIDVHARDVVAKMIVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYL Sbjct: 1741 KIMTICTIDVHARDVVAKMIVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYL 1800 Query: 1801 GNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCS 1860 GNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCS Sbjct: 1801 GNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCS 1860 Query: 1861 EQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLG 1920 EQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLG Sbjct: 1861 EQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLG 1920 Query: 1921 EIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEAR 1980 EIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEAR Sbjct: 1921 EIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEAR 1980 Query: 1981 LLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDF 2040 LLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDF Sbjct: 1981 LLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDF 2040 Query: 2041 NIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQL 2100 NIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQL Sbjct: 2041 NIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQL 2100 Query: 2101 EELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPV 2160 EELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPV Sbjct: 2101 EELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPV 2160 Query: 2161 TREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIP 2220 TREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIP Sbjct: 2161 TREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIP 2220 Query: 2221 LNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMIL 2280 LNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMIL Sbjct: 2221 LNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMIL 2280 Query: 2281 FDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFT 2340 FDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFT Sbjct: 2281 FDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFT 2340 Query: 2341 CFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVP 2400 CFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVP Sbjct: 2341 CFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVP 2400 Query: 2401 SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNT 2460 SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNT Sbjct: 2401 SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNT 2460 Query: 2461 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT 2520 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT Sbjct: 2461 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT 2520 Query: 2521 VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSF 2580 VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSF Sbjct: 2521 VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSF 2580 Query: 2581 PGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVF 2640 PGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVF Sbjct: 2581 PGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVF 2640 Query: 2641 NLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTK 2700 NLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTK Sbjct: 2641 NLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTK 2700 Query: 2701 KFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMNLV 2760 KFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMNLV Sbjct: 2701 KFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMNLV 2760 Query: 2761 LFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIP 2820 LFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIP Sbjct: 2761 LFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIP 2820 Query: 2821 DLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENII 2880 DLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENII Sbjct: 2821 DLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENII 2880 Query: 2881 SSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAI 2940 SSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAI Sbjct: 2881 SSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAI 2940 Query: 2941 DWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNY 3000 DWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNY Sbjct: 2941 DWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNY 3000 Query: 3001 TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELK 3060 TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELK Sbjct: 3001 TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELK 3060 Query: 3061 QKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALL 3120 QKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALL Sbjct: 3061 QKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALL 3120 Query: 3121 AAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKV 3180 AAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKV Sbjct: 3121 AAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKV 3180 Query: 3181 DTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEV 3240 DTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEV Sbjct: 3181 DTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEV 3240 Query: 3241 YCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEA 3300 YCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEA Sbjct: 3241 YCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEA 3300 Query: 3301 DATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYR 3360 DATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYR Sbjct: 3301 DATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYR 3360 Query: 3361 NELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGN 3420 NELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGN Sbjct: 3361 NELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGN 3420 Query: 3421 TERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVD 3480 TERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVD Sbjct: 3421 TERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVD 3480 Query: 3481 PVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT 3540 PVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT Sbjct: 3481 PVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT 3540 Query: 3541 RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT 3600 RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT Sbjct: 3541 RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT 3600 Query: 3601 ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV 3660 ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV Sbjct: 3601 ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV 3660 Query: 3661 YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV 3720 YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV Sbjct: 3661 YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV 3720 Query: 3721 TFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIE 3780 TFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIE Sbjct: 3721 TFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIE 3780 Query: 3781 GSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKF 3840 GSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKF Sbjct: 3781 GSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKF 3840 Query: 3841 VEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQ 3900 VEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQ Sbjct: 3841 VEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQ 3900 Query: 3901 EVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGSHEDYRVFI 3960 EVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGSHEDYRVFI Sbjct: 3901 EVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGSHEDYRVFI 3960 Query: 3961 SAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCM 4020 SAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCM Sbjct: 3961 SAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCM 4020 Query: 4021 LFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFG 4080 LFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFG Sbjct: 4021 LFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFG 4080 Query: 4081 EIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLP 4140 EIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLP Sbjct: 4081 EIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLP 4140 Query: 4141 PESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSE 4200 PESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSE Sbjct: 4141 PESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSE 4200 Query: 4201 RKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECER 4260 RKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECER Sbjct: 4201 RKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECER 4260 Query: 4261 MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY 4320 MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY Sbjct: 4261 MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY 4320 Query: 4321 ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT 4380 ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT Sbjct: 4321 ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT 4380 Query: 4381 KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME 4440 KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME Sbjct: 4381 KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME 4440 Query: 4441 TKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV 4485 TKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV Sbjct: 4441 TKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV 4485 >gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo sapiens] Length = 4485 Score = 8947 bits (23217), Expect = 0.0 Identities = 4481/4485 (99%), Positives = 4483/4485 (99%) Query: 1 MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60 MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG Sbjct: 1 MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60 Query: 61 MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120 MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL Sbjct: 61 MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120 Query: 121 LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180 LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER Sbjct: 121 LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180 Query: 181 IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC 240 IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWD RLLNLKC Sbjct: 181 IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDTRLLNLKC 240 Query: 241 IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300 IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME Sbjct: 241 IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300 Query: 301 QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360 QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK Sbjct: 301 QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360 Query: 361 GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420 GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF Sbjct: 361 GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420 Query: 421 FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480 FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD Sbjct: 421 FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480 Query: 481 PGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAE 540 PGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAE Sbjct: 481 PGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAE 540 Query: 541 VAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLE 600 VAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLE Sbjct: 541 VAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLE 600 Query: 601 VSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPL 660 VSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPL Sbjct: 601 VSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPL 660 Query: 661 ILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELI 720 ILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELI Sbjct: 661 ILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELI 720 Query: 721 VGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQN 780 VGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQN Sbjct: 721 VGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQN 780 Query: 781 RMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQ 840 RMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQ Sbjct: 781 RMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQ 840 Query: 841 AMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFE 900 AMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFE Sbjct: 841 AMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFE 900 Query: 901 IRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMNYKMDLEDNT 960 IRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMNYKMDLEDNT Sbjct: 901 IRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMNYKMDLEDNT 960 Query: 961 DLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTW 1020 DLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTW Sbjct: 961 DLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTW 1020 Query: 1021 TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW 1080 TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW Sbjct: 1021 TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW 1080 Query: 1081 GFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATD 1140 GFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATD Sbjct: 1081 GFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATD 1140 Query: 1141 NMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSIL 1200 NMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSIL Sbjct: 1141 NMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSIL 1200 Query: 1201 RRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKVFLLKGIMEALSKSGGLFEVPVP 1260 RRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKVFLLKGIMEALSKSGGLFEVPVP Sbjct: 1201 RRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKVFLLKGIMEALSKSGGLFEVPVP 1260 Query: 1261 DYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLD 1320 DYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLD Sbjct: 1261 DYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLD 1320 Query: 1321 KEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLAD 1380 KEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLAD Sbjct: 1321 KEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLAD 1380 Query: 1381 LLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEV 1440 LLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEV Sbjct: 1381 LLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEV 1440 Query: 1441 LVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFI 1500 LVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFI Sbjct: 1441 LVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFI 1500 Query: 1501 GSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICE 1560 GSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICE Sbjct: 1501 GSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICE 1560 Query: 1561 KALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASD 1620 KALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASD Sbjct: 1561 KALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASD 1620 Query: 1621 KPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPR 1680 KPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPR Sbjct: 1621 KPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPR 1680 Query: 1681 EQWILDYPAQIWWTTEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRM 1740 EQWILDYPAQIWWTTEVGLAFARLEEGYENAI+DYNKKQISQLNVLITLL+GNLNAGDRM Sbjct: 1681 EQWILDYPAQIWWTTEVGLAFARLEEGYENAIRDYNKKQISQLNVLITLLMGNLNAGDRM 1740 Query: 1741 KIMTICTIDVHARDVVAKMIVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYL 1800 KIMTICTIDVHARDVVAKMIVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYL Sbjct: 1741 KIMTICTIDVHARDVVAKMIVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYL 1800 Query: 1801 GNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCS 1860 GNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCS Sbjct: 1801 GNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCS 1860 Query: 1861 EQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLG 1920 EQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLG Sbjct: 1861 EQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLG 1920 Query: 1921 EIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEAR 1980 EIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEAR Sbjct: 1921 EIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEAR 1980 Query: 1981 LLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDF 2040 LLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDF Sbjct: 1981 LLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDF 2040 Query: 2041 NIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQL 2100 NIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQL Sbjct: 2041 NIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQL 2100 Query: 2101 EELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPV 2160 EELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPV Sbjct: 2101 EELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPV 2160 Query: 2161 TREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIP 2220 TREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIP Sbjct: 2161 TREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIP 2220 Query: 2221 LNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMIL 2280 LNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMIL Sbjct: 2221 LNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMIL 2280 Query: 2281 FDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFT 2340 FDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFT Sbjct: 2281 FDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFT 2340 Query: 2341 CFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVP 2400 CFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVP Sbjct: 2341 CFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVP 2400 Query: 2401 SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNT 2460 SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNT Sbjct: 2401 SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNT 2460 Query: 2461 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT 2520 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT Sbjct: 2461 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT 2520 Query: 2521 VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSF 2580 VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSF Sbjct: 2521 VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSF 2580 Query: 2581 PGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVF 2640 PGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVF Sbjct: 2581 PGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVF 2640 Query: 2641 NLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTK 2700 NLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTK Sbjct: 2641 NLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTK 2700 Query: 2701 KFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMNLV 2760 KFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMNLV Sbjct: 2701 KFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMNLV 2760 Query: 2761 LFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIP 2820 LFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIP Sbjct: 2761 LFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIP 2820 Query: 2821 DLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENII 2880 DLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENII Sbjct: 2821 DLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENII 2880 Query: 2881 SSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAI 2940 SSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAI Sbjct: 2881 SSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAI 2940 Query: 2941 DWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNY 3000 DWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNY Sbjct: 2941 DWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNY 3000 Query: 3001 TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELK 3060 TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELK Sbjct: 3001 TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELK 3060 Query: 3061 QKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALL 3120 QKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALL Sbjct: 3061 QKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALL 3120 Query: 3121 AAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKV 3180 AAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKV Sbjct: 3121 AAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKV 3180 Query: 3181 DTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEV 3240 DTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEV Sbjct: 3181 DTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEV 3240 Query: 3241 YCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEA 3300 YCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEA Sbjct: 3241 YCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEA 3300 Query: 3301 DATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYR 3360 DATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYR Sbjct: 3301 DATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYR 3360 Query: 3361 NELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGN 3420 NELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGN Sbjct: 3361 NELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGN 3420 Query: 3421 TERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVD 3480 TERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVD Sbjct: 3421 TERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVD 3480 Query: 3481 PVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT 3540 PVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT Sbjct: 3481 PVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT 3540 Query: 3541 RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT 3600 RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT Sbjct: 3541 RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT 3600 Query: 3601 ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV 3660 ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV Sbjct: 3601 ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV 3660 Query: 3661 YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV 3720 YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV Sbjct: 3661 YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV 3720 Query: 3721 TFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIE 3780 TFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIE Sbjct: 3721 TFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIE 3780 Query: 3781 GSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKF 3840 GSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKF Sbjct: 3781 GSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKF 3840 Query: 3841 VEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQ 3900 VEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQ Sbjct: 3841 VEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQ 3900 Query: 3901 EVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGSHEDYRVFI 3960 EVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLE YSTGSHEDYRVFI Sbjct: 3901 EVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLEHYSTGSHEDYRVFI 3960 Query: 3961 SAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCM 4020 SAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCM Sbjct: 3961 SAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCM 4020 Query: 4021 LFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFG 4080 LFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFG Sbjct: 4021 LFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFG 4080 Query: 4081 EIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLP 4140 EIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLP Sbjct: 4081 EIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLP 4140 Query: 4141 PESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSE 4200 PESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSE Sbjct: 4141 PESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSE 4200 Query: 4201 RKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECER 4260 RKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECER Sbjct: 4201 RKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECER 4260 Query: 4261 MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY 4320 MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY Sbjct: 4261 MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY 4320 Query: 4321 ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT 4380 ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT Sbjct: 4321 ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT 4380 Query: 4381 KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME 4440 KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME Sbjct: 4381 KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME 4440 Query: 4441 TKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV 4485 TKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV Sbjct: 4441 TKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV 4485 >gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo sapiens] Length = 4470 Score = 8792 bits (22813), Expect = 0.0 Identities = 4433/4511 (98%), Positives = 4441/4511 (98%), Gaps = 67/4511 (1%) Query: 1 MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60 MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG Sbjct: 1 MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60 Query: 61 MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120 MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL Sbjct: 61 MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120 Query: 121 LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180 LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER Sbjct: 121 LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180 Query: 181 IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC 240 IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC Sbjct: 181 IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC 240 Query: 241 IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300 IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME Sbjct: 241 IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300 Query: 301 QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360 QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK Sbjct: 301 QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360 Query: 361 GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420 GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF Sbjct: 361 GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420 Query: 421 FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480 FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD Sbjct: 421 FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480 Query: 481 PGDS------------NFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMC 528 PGDS NFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMC Sbjct: 481 PGDSVGPRAGLDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMC 540 Query: 529 GGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQ 588 GGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQ Sbjct: 541 GGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQ 600 Query: 589 LKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGV 648 LKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGV Sbjct: 601 LKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGV 660 Query: 649 DQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENE 708 DQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENE Sbjct: 661 DQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENE 720 Query: 709 TFRKFVGNLELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYI 768 TFRKFVGNLELIVGWYNE+ +KAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYI Sbjct: 721 TFRKFVGNLELIVGWYNEV---MKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYI 777 Query: 769 QEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKR 828 QEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKR Sbjct: 778 QEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKR 837 Query: 829 YAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDN 888 YAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDN Sbjct: 838 YAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDN 897 Query: 889 MVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKD 948 MVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKD Sbjct: 898 MVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKD 957 Query: 949 RMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIY 1008 RMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIY Sbjct: 958 RMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIY 1017 Query: 1009 GCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP 1068 GCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP Sbjct: 1018 GCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP 1077 Query: 1069 FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGH 1128 FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGH Sbjct: 1078 FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGH 1137 Query: 1129 LMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLT 1188 LMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLT Sbjct: 1138 LMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLT 1197 Query: 1189 VAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNK----VFLLKGI 1244 VAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNK + ++GI Sbjct: 1198 VAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAMEGI 1257 Query: 1245 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ 1304 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ Sbjct: 1258 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ 1317 Query: 1305 MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ 1364 MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ Sbjct: 1318 MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ 1377 Query: 1365 ATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQH 1424 ATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQH Sbjct: 1378 ATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQH 1437 Query: 1425 EPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISI 1484 EPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISI Sbjct: 1438 EPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISI 1497 Query: 1485 WFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPG 1544 WFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPG Sbjct: 1498 WFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPG 1557 Query: 1545 LYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSK 1604 LYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSK Sbjct: 1558 LYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSK 1617 Query: 1605 LFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTL 1664 LFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTL Sbjct: 1618 LFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTL 1677 Query: 1665 RHEIPEAVVTYEEKPREQWILDYPAQ-------IWWTTEVGLAFARLEEGYENAIKDYNK 1717 RHEIPEAVVTYEEKPREQWILDYPAQ IWWTTEVGLAFARLEEGYENAI+DYNK Sbjct: 1678 RHEIPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNK 1737 Query: 1718 KQISQLNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMIV---ESSQAFTWQAQLR 1774 KQISQLNVLITLL+GNLNAGDRMKIMTICTIDVHARDVVAKMIV ESSQAFTWQAQLR Sbjct: 1738 KQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLR 1797 Query: 1775 HRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGP 1834 HRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGP Sbjct: 1798 HRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGP 1857 Query: 1835 AGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEV 1894 AGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEV Sbjct: 1858 AGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEV 1917 Query: 1895 LSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFR 1954 LSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFR Sbjct: 1918 LSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFR 1977 Query: 1955 PCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVL 2014 PCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVL Sbjct: 1978 PCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVL 2037 Query: 2015 VVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF 2074 VVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF Sbjct: 2038 VVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF 2097 Query: 2075 EKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL 2134 EKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL Sbjct: 2098 EKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL 2157 Query: 2135 KRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDID 2194 KRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDID Sbjct: 2158 KRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDID 2217 Query: 2195 PMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPAD 2254 PMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPAD Sbjct: 2218 PMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPAD 2277 Query: 2255 LGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYL 2314 LGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYL Sbjct: 2278 LGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYL 2337 Query: 2315 LECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKF 2374 LECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKF Sbjct: 2338 LECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKF 2397 Query: 2375 PSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKS 2434 PSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKS Sbjct: 2398 PSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKS 2457 Query: 2435 WPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRN 2494 WPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRN Sbjct: 2458 WPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRN 2517 Query: 2495 YGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVA 2554 YGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVA Sbjct: 2518 YGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVA 2577 Query: 2555 CMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQL 2614 CMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQL Sbjct: 2578 CMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQL 2637 Query: 2615 VAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHET 2674 VAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHET Sbjct: 2638 VAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHET 2697 Query: 2675 ERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVT 2734 ERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVT Sbjct: 2698 ERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVT 2757 Query: 2735 DMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQ 2794 DMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQ Sbjct: 2758 DMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQ 2817 Query: 2795 SLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQF 2854 SLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQF Sbjct: 2818 SLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQF 2877 Query: 2855 LVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVI 2914 LVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVI Sbjct: 2878 LVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVI 2937 Query: 2915 LCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASIS 2974 LCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIP +KASIS Sbjct: 2938 LCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIP-VIKASIS 2996 Query: 2975 FFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENG 3034 FFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENG Sbjct: 2997 FFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENG 3056 Query: 3035 LMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKV 3094 LMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKV Sbjct: 3057 LMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKV 3116 Query: 3095 EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAV 3154 EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAV Sbjct: 3117 EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAV 3176 Query: 3155 MILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDP 3214 MILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDP Sbjct: 3177 MILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDP 3236 Query: 3215 EFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE 3274 EFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE Sbjct: 3237 EFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE 3296 Query: 3275 LNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQ 3334 LNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQ Sbjct: 3297 LNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQ 3356 Query: 3335 GVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDD 3394 GVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDD Sbjct: 3357 GVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDD 3416 Query: 3395 ADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQK 3454 ADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQK Sbjct: 3417 ADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQK 3476 Query: 3455 SYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLI 3514 SYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLI Sbjct: 3477 SYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLI 3536 Query: 3515 LHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEF 3574 LHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEF Sbjct: 3537 LHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEF 3596 Query: 3575 KIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEAR 3634 KIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEAR Sbjct: 3597 KIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEAR 3656 Query: 3635 ENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTD 3694 ENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTD Sbjct: 3657 ENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTD 3716 Query: 3695 EITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDF 3754 EITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDF Sbjct: 3717 EITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDF 3776 Query: 3755 LQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLC 3814 LQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLC Sbjct: 3777 LQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLC 3836 Query: 3815 MVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKD 3874 MVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKD Sbjct: 3837 MVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKD 3896 Query: 3875 VEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLV 3934 VEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ NIHLV Sbjct: 3897 VEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ--------NIHLV 3948 Query: 3935 ARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHA 3994 ARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHA Sbjct: 3949 ARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHA 4008 Query: 3995 NLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLT 4054 NLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLT Sbjct: 4009 NLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLT 4068 Query: 4055 ISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDV 4114 ISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDV Sbjct: 4069 ISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDV 4128 Query: 4115 LLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQP 4174 LLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQP Sbjct: 4129 LLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQP 4188 Query: 4175 KETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPET 4234 KETDSGAGTGVSREEK VKAVLDDILEKIPET Sbjct: 4189 KETDSGAGTGVSREEK-----------------------------VKAVLDDILEKIPET 4219 Query: 4235 FNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLST 4294 FNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLST Sbjct: 4220 FNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLST 4279 Query: 4295 ALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSF 4354 ALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSF Sbjct: 4280 ALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSF 4339 Query: 4355 LTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVI 4414 LTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVI Sbjct: 4340 LTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVI 4399 Query: 4415 AEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKW 4474 AEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKW Sbjct: 4400 AEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKW 4459 Query: 4475 ILAAVALLLQV 4485 ILAAVALLLQV Sbjct: 4460 ILAAVALLLQV 4470 >gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens] Length = 4486 Score = 5712 bits (14817), Expect = 0.0 Identities = 2806/4506 (62%), Positives = 3513/4506 (77%), Gaps = 67/4506 (1%) Query: 6 DVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQ----VLVLTLNAAGM 61 D RL L ++ L+ W + G+ E L F + + +LV+ G+ Sbjct: 22 DRRLRLLGTYVAMSLRPAAGAWERCAGSAEAEQLLQAFLGRDAAEGPRPLLVVRPGPRGL 81 Query: 62 II-PCLGF-PQS--LKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVL 117 I P L P+S +K ++F++T E D++R ++ GD+ P++ L A+ EV+ Sbjct: 82 AIRPGLEVGPESGLAGAKALFFLRTGPEPPGPDSFRGAVVCGDLPAAPLEHLAALFSEVV 141 Query: 118 SSLLNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLES 177 +L +N WP ++ ED+ + H L+ ++ V+ ++KGKTLLP+P ++ Sbjct: 142 LPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFADSK 201 Query: 178 MERIPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLN 237 E + S+D +++AIE+ +I WS+Q++ VL ++S+Q LL G +P P+VE EFW +R + Sbjct: 202 SETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKSRYED 261 Query: 238 LKCIHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLE 297 LK I+ QL V + ++L+K +S Y+PA + +Y +V L EA DI ++L PL+ LE Sbjct: 262 LKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQRHLE 321 Query: 298 EMEQADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEE 357 +E A+F + + +L +C IWAT + Y +P R+ V+LQE CN +I+ +LSPE+ Sbjct: 322 ALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQEICNLLIQQASNYLSPED 381 Query: 358 VLKGLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVP-WEFPSSLAFSR 416 +L+ E+EE + + + L Q + N+ +FK+ + V W+F SSL F R Sbjct: 382 LLRS---EVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQEVKEWDFQSSLVFVR 438 Query: 417 INSFFQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKY 476 ++ F ++ +E L KTA++F KL K+E GVRGN L V ++++E E+ ++ + Sbjct: 439 LDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQEMYRLLSGSSS 498 Query: 477 DPLDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPL 536 D L ++F+ D ++F K++DLDRRL TIF Q FDD ++ + KLL + G L+ERPL Sbjct: 499 DCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHAFKLLDIAGNLLERPL 558 Query: 537 ILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQ 596 + + + +Y V++++F+ +LD +++Y + E +HKNMP VAG L+W+ EL+ Sbjct: 559 VARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVHKNMPTVAGGLRWAQELR 618 Query: 597 ERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNL 656 +R++ + + HP M AE K QKY++M+ LL + ++Y+ W V + +NL Sbjct: 619 QRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYETRLYEDWCRTVSEKSQYNL 678 Query: 657 GQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGN 716 QPL+ RD + I +NF+ L++VL+E+ YL ++ K +P++A ++FS + +R+ V N Sbjct: 679 SQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPETAAAMFSSRDFYRQLVAN 738 Query: 717 LELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILH 776 LEL+ WYN++ + VEF L++ EL+ ID++L +AE TL W EG+ Y+ E+ +H Sbjct: 739 LELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKTEGICDYVTEITSSIH 798 Query: 777 NLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAG 836 +L+ R+QK K N+E I MK W P+F+ KD K+E+LL LD R + K Y ++++G Sbjct: 799 DLEQRIQKTKDNVEEIQNIMKTW-VTPIFKTKDGKRESLLSLDDRHDRMEKYYNLIKESG 857 Query: 837 VKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIA 896 +KI A+V EN LF AD S WK YV ID+++L+ F I SL +L++N + Sbjct: 858 LKIHALVQENLGLFSADPTSNIWKTYVNSIDNLLLNGFFLAIECSLKYLLENTECKAGLT 917 Query: 897 PLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDR--MNYKM 954 P+FE ++ L L F P+LE G GF ++EGL+ I+ + L+PRL+ +Y++ Sbjct: 918 PIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPSLVPRLSPQNGSPHYQV 977 Query: 955 DLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTA 1014 DL+ DL MR + V M YQ +F +YSYL+ ++ +E + FL+YG +T Sbjct: 978 DLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVEDRKEVLGQFLLYGHILTP 1037 Query: 1015 EDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALL 1074 E+++ +D IP+ PP L+QF+ QIDSYE LYEEV + E KVF GW++ D RPFK +LL Sbjct: 1038 EEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKVFDGWMKIDIRPFKASLL 1097 Query: 1075 STIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKE 1134 + I+RW +FK+HL +HVT+SLA+L+AF+K + GL K +++GD+ GLVE+MGHLM VKE Sbjct: 1098 NIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKGDFQGLVEIMGHLMAVKE 1157 Query: 1135 RQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQA 1194 RQ+ TD MFEPLKQTIELLKTY +E+PE + +L+ELPE W N KK+AI VK VAPLQA Sbjct: 1158 RQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNIKKVAITVKQQVAPLQA 1217 Query: 1195 NEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLN----KVFLLKGIMEALSK 1250 NEV++LR++C F+ +Q +F E+F +EAPF F +P++ L+ ++ ++ M ++S+ Sbjct: 1218 NEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDARHIEIQQMESTMASISE 1277 Query: 1251 SGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCK 1310 S LFEV VPDYKQL+ C +EV LKELWD + +V +SI W+TT W++INVE M+++CK Sbjct: 1278 SASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECK 1337 Query: 1311 KFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKF 1370 +FA+ +R+LDKE++ WDAF GL++TV N ++SLRAV+ELQNPAIRERHW+QLMQAT V F Sbjct: 1338 QFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSF 1397 Query: 1371 KMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRT 1430 M ++TTLA LLQL LH YEDEVR IVDKA KE GMEK LK L +TW+ MEFQ+EPHPRT Sbjct: 1398 TMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRT 1457 Query: 1431 GTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQR 1490 +L S E L+E LEDNQVQLQNL+MSKY+A FL+EV+ WQ+KLST D+VISIWFEVQR Sbjct: 1458 NVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQR 1517 Query: 1491 TWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLE 1550 TW+HLESIF GSEDIR QLP DS+RF+ I+ +FK L DA K PNVV+ T+KPGLY KLE Sbjct: 1518 TWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLE 1577 Query: 1551 ALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLC 1610 ++ L +CEKALAEYL+TKRLAFPRFYF+SS+DLLDILSNG P +V RHLSKLFD++ Sbjct: 1578 DIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMA 1637 Query: 1611 KLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPE 1670 K++F+LDAS +P K LGMYSKE+EY+ F + CD SGQVE+WLN VL M +T+RHE+ E Sbjct: 1638 KMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTE 1697 Query: 1671 AVVTYEEKPREQWILDYPAQ-------IWWTTEVGLAFARLEEGYENAIKDYNKKQISQL 1723 V YEEKPREQW+ D+PAQ IWWTTEVG+AFARLEEGYE+A+KDY KKQ++QL Sbjct: 1698 GVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQL 1757 Query: 1724 NVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEE 1780 LIT+LIG L+ GDR KIMTICTIDVHARDVVAKMI V+++QAF W +QLRHRWD+E Sbjct: 1758 KTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDE 1817 Query: 1781 KRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKT 1840 +HCFANICDAQ YSYEYLGNTPRLVITPLTDRCYITLTQSLHL M GAPAGPAGTGKT Sbjct: 1818 VKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKT 1877 Query: 1841 ETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAV 1900 ETTKDLGRALG +VYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSV+AV Sbjct: 1878 ETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAV 1937 Query: 1901 QVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVV 1960 QVK +QDAIR KK+ F+FLGE I L P+VGIFITMNPGYAGR ELPENLK+LFRPCAMVV Sbjct: 1938 QVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVV 1997 Query: 1961 PDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSL 2020 PDFELICEIML+AEGF+EA+ LARKFITLY LCKELLSKQDHYDWGLRAIKSVLVVAGSL Sbjct: 1998 PDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSL 2057 Query: 2021 KRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQ 2080 KRGDP R EDQVLMR+LRDFNIPKIVTDD+P+FMGLIGDLFPALDVPR+RD NFE ++++ Sbjct: 2058 KRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRK 2117 Query: 2081 SIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVA 2140 +IV+LKLQAED+FVLKVVQLEELL VRHSVF+VG AG+GKSQVL+SL+KTYQ +KR+PV Sbjct: 2118 AIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKRRPVW 2177 Query: 2141 VDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIES 2200 DL+PKAVT DELFGIINP T EWKDGLFS+IMR+LANITHDGPKWI+LDGDIDPMWIES Sbjct: 2178 TDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDGPKWILLDGDIDPMWIES 2237 Query: 2201 LNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPV 2260 LNTVMDDNKVLTLASNERIPLN TM+L+FEISHLRTATPATVSRAGILYINPADLGWNP Sbjct: 2238 LNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPP 2297 Query: 2261 VSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLT 2320 VSSWIE+R++Q+E+ANL ILFDKYLPTCLD LR FKKI P+PE +++Q + +LLECLLT Sbjct: 2298 VSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLT 2357 Query: 2321 EKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTI 2380 + +P D P+E+YE YFVF WAFGGAM QDQLVDYR EFSKWW+ EFKT+KFPSQGTI Sbjct: 2358 TEDIPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSKWWLTEFKTVKFPSQGTI 2417 Query: 2381 FDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLV 2440 FDYYIDP+TKKF PW+ VP FE DP++PLQA LVHT+ETIR+ YFM+ LM + PVMLV Sbjct: 2418 FDYYIDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLV 2477 Query: 2441 GNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGT 2500 G AGTGKSVL+G KL SL+ + YLV+ VPFN+YTTSAMLQ VLEKPLEKK+GRNYGPPG Sbjct: 2478 GTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGN 2537 Query: 2501 KKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTS 2560 KKL+YFIDDMNMPEVD YGTV PHT+IRQH+D+ HWYDR KL+LK+I N QYV+CMNPT+ Sbjct: 2538 KKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQYVSCMNPTA 2597 Query: 2561 GSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALA 2620 GSFTI+ RLQRHF VF +SFPG +AL++IY+ ILTQHL + ++Q+ L+ ALA Sbjct: 2598 GSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLALA 2657 Query: 2621 LHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGD 2680 HQKI TFLPT IKFHY+FNLRD +NIFQG+LFS+ E +K+ DL+RL+LHE+ RVY D Sbjct: 2658 FHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRD 2717 Query: 2681 KMVDEKDQETLHRVTMASTKKFFDDLGDELLFAK-PNIFCHFAQGIGDPKYVPVTDMAPL 2739 KMV+EKD + ++ KK FDD+ D + + PN++CHFA GIG+PKY+PV L Sbjct: 2718 KMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFANGIGEPKYMPVQSWELL 2777 Query: 2740 NKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRL 2799 + LV+ L+++NEVN VM+LVLFEDA+ H+C INRILESPRGNALLVGVGGSGKQSL+RL Sbjct: 2778 TQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQSLTRL 2837 Query: 2800 AAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLIN 2859 AA+IS +DVFQITL+KGY I D K+DLA+ +KA VKN+ +VFLMTD+QVA+E+FLVLIN Sbjct: 2838 AAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVLIN 2897 Query: 2860 DLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSP 2919 DLLASGEIP L+ +DEVENIIS++R +VKS G+ D RE CWKFFI+++RRQLKV LCFSP Sbjct: 2898 DLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKFFIDRIRRQLKVTLCFSP 2957 Query: 2920 VGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSY 2979 VG+ LRVR+RKFPA+VNCTAI WFHEWP+ AL SVS RFL+ TEGI VK SIS FM++ Sbjct: 2958 VGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQSISKFMAF 3017 Query: 2980 VHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQ 3039 VHT+VN+ S+ YL+ E+RYNYTTPK+FLE I+LYQ+LL + R EL K ERLENGL+KL Sbjct: 3018 VHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLH 3077 Query: 3040 STASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINK 3099 ST++QVDDLKAKLA QE ELKQKNE AD+LIQVVG+E +KVS+EKA+AD+EE KV VI Sbjct: 3078 STSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIML 3137 Query: 3100 NVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTA 3159 V +KQK CE DLAKAEPAL AAQ AL+TLNK NLTELKSFGSPP AV NV+AAVM+L A Sbjct: 3138 EVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMA 3197 Query: 3160 PGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRS 3219 P G++PKD+SWKAAK+ M KVD FLDSL F+KE+I E CLKA +PY +P F+PEF+ + Sbjct: 3198 PRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDPEFNPEFVAT 3257 Query: 3220 KSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANL 3279 KS AAAGLCSW INIVRFYEV+CDV PKRQAL +A A+L AQEKL+ IK KIA LN NL Sbjct: 3258 KSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENL 3317 Query: 3280 SNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLC 3339 + LT+ FEKATA+K+KCQQEA+ T I LANRLVGGLASEN+RWA++V+NF+ Q TLC Sbjct: 3318 AKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLC 3377 Query: 3340 GDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVAT 3399 GD+LLI+AF+SY+G+FTKKYR L+++ W PY+ LK PIP+T LDPL +L DDADVA Sbjct: 3378 GDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPLRMLMDDADVAA 3437 Query: 3400 WNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDV 3459 W N+GLP+DRMS ENATIL N ERWPL+VD QLQGIKWIKNKY +L+ ++GQK YL + Sbjct: 3438 WQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYGEDLRVTQIGQKGYLQI 3497 Query: 3460 IEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKY 3519 IEQA+ G +LIEN+ E++DPVL PLLGR IKKG++IKIGDKE EY+PKFRLILHTK Sbjct: 3498 IEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGDKECEYNPKFRLILHTKL 3557 Query: 3520 FNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLK 3579 NPHY+PE+QAQ TLINF VTRDGLEDQLLAAVV+ ERPDLEQLK++LTK QN FKI LK Sbjct: 3558 ANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKITLK 3617 Query: 3580 ELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRP 3639 LEDSLL+RLS+ASGNFLG+T LVENLE TK TA+E+E+KV EAK+TEVKINEARE+YRP Sbjct: 3618 TLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAREHYRP 3677 Query: 3640 AAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYS 3699 AA RASLLYFI+NDL+KI+P+YQFSLKAF++VF+KA++R P +++RV NL D IT+S Sbjct: 3678 AAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFS 3737 Query: 3700 VYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQG 3759 VY YT RGLFE DKL +LAQ+TFQ+L M +E+N VELDFLLR P + G SPV+FL HQ Sbjct: 3738 VYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVEFLSHQA 3797 Query: 3760 WGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCL 3819 WG +K LS M+EF NLD DIEGSAK WKK VESE PEKE P+EWKNKTALQ+LCM+R + Sbjct: 3798 WGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTALQRLCMLRAM 3857 Query: 3820 RPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALG 3879 RPDRMTYA+++FVEEK+GSK+V GR+++F+ S+EES P+T +FFILSPGVDPLKDVE+ G Sbjct: 3858 RPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQG 3917 Query: 3880 KKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLG 3939 +KLG+T +N HNVSLGQGQEVVAE ALD+AA+KGHWVILQ NIHLVA+WL Sbjct: 3918 RKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQ--------NIHLVAKWLS 3969 Query: 3940 TLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKA 3999 TL+KKLE +S SH ++RVF+SAEPAPSPE HIIPQGILEN+IKITNEPPTGMHANLHKA Sbjct: 3970 TLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKA 4029 Query: 4000 LDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINV 4059 LD FTQDTLEMC++E EFK +LFALCYFHAVVAERRKFG QGWNRSYPFN GDLTIS+NV Sbjct: 4030 LDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNV 4089 Query: 4060 LYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG 4119 LYN+LEAN KVP+DDLRYLFGEIMYGGHITDDWDRRLCRTYL E+IR EMLEG++ LAPG Sbjct: 4090 LYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPG 4149 Query: 4120 FQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDS 4179 F +P N+DY GYH+YID LPPESPYLYGLHPNAEIGFLT TSEKLFRTVLE+QP+++ + Sbjct: 4150 FPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQA 4209 Query: 4180 GAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAE 4239 G G +REEK VKA+L++ILE++ + FN+ E Sbjct: 4210 RDGAGATREEK-----------------------------VKALLEEILERVTDEFNIPE 4240 Query: 4240 IMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYD 4299 +MAK E+TPY+VVAFQEC RMNILT E++RSL+EL LGLKGELT+T+ +E+L AL++D Sbjct: 4241 LMAKVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFD 4300 Query: 4300 TVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIM 4359 VP++W RAYPS GLAAW+ DLL RI+ELEAWT DF +P+TVWL GFFNPQSFLTAIM Sbjct: 4301 MVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIM 4360 Query: 4360 QSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARL 4419 QS ARKNEWPLD+M L ++TKKNRE+ +PPREG+Y++GLFMEGA WDTQ G+I EA+L Sbjct: 4361 QSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKL 4420 Query: 4420 KELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAV 4479 K+LTP MPV+FIKAIP D+ + +++Y CPVYKT RGPTYVWTFNLKTKE +KW+LA V Sbjct: 4421 KDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPTYVWTFNLKTKENPSKWVLAGV 4480 Query: 4480 ALLLQV 4485 ALLLQ+ Sbjct: 4481 ALLLQI 4486 >gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] Length = 4523 Score = 5294 bits (13732), Expect = 0.0 Identities = 2620/4516 (58%), Positives = 3367/4516 (74%), Gaps = 78/4516 (1%) Query: 2 TMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAGM 61 + A D R+ +L +++L F +KWS+ + +E+N + EF E LV + A+G Sbjct: 52 SFAQDARVRFLGGRLAMMLGFTEEKWSQYLESEDNRQVLGEFLESTSPACLVFSFAASGR 111 Query: 62 IIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSLL 121 + P+ K V+ K +E+I +++ +L+G++ + + A ++E+L +L Sbjct: 112 LAASQEIPRDANHKLVFISKKITESIGVNDFSQVVLFGELPALSLGHVSAFLDEILVPVL 171 Query: 122 NQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMERI 181 + N W S+D+ + +K +M++ GK+ +TLLPIP G +D E Sbjct: 172 SNKNNHKSWSCFTSQDMEYHIEVMKKKMYIFRGKMSRRTLLPIPTVAGKMDLDQNCSENK 231 Query: 182 PSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCI 241 P S + ++LHAIE+ +I+WSHQI++++ +DS Q LL+GLH PQ E +FW R NL CI Sbjct: 232 PPSNERIILHAIESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQAELDFWMMRRENLSCI 291 Query: 242 HEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQ 301 ++QL P V K+V+IL +S Y+P L++++ V L EA D+ LYL+PLR ++ +++ Sbjct: 292 YDQLQAPVVLKMVKILTTKQSSYFPTLKDIFLAVENALLEAQDVELYLRPLRRHIQCLQE 351 Query: 302 ADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLKG 361 +F IA + TIC IW+ S++YNTPAR+IV+LQEFCN I +LSPE++L+G Sbjct: 352 TEFPQTRILIAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFINQATAYLSPEDLLRG 411 Query: 362 LQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFF 421 EIEE L + +AVN+LK ++ + +F ++ PW+F S L F R + F Sbjct: 412 ---EIEESLEKVQVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDFQSHLVFCRFDKFL 468 Query: 422 QRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLDP 481 R+ IE+++ T +EF KLE++E GG +G +L V + +E+ EL K+F YDP D Sbjct: 469 DRLIKIEDIFATTLEFEKLERLEFGGTKGAILNGQVHEMSEELMELCKLFKQSTYDPSDC 528 Query: 482 GDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAEV 541 + F+ DY F+ K + DRRL TI C+ F +C+ ++++ KLL + G +E+P+++ Sbjct: 529 TNMEFESDYVAFKSKTLEFDRRLGTIICEAFFNCNGLEAAFKLLTIFGNFLEKPVVMEIF 588 Query: 542 APRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLEV 601 + YS ++ +F+ ELD K LY+ M E G++ +++KNMP +G +KW+ ++ +RL++ Sbjct: 589 SLHYSTLVHMFNTELDVCKQLYNEHMKQIECGHV-VLNKNMPFTSGNMKWAQQVLQRLQM 647 Query: 602 SMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPLI 661 + + + + + L YQKY EM LL +IY +W + VD+ C FNL QPL+ Sbjct: 648 FWSNFASLRYLFLGNPDHALVYQKYVEMTTLLDQFESRIYNEWKSNVDEICEFNLNQPLV 707 Query: 662 LRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELIV 721 A + L+ VNF LVAVLREVKYL ++++IPDSA ++F + T K++GNL+L+V Sbjct: 708 KFSAINGLLCVNFDPKLVAVLREVKYLLMLKKQDIPDSALAIFKKRNTILKYIGNLDLLV 767 Query: 722 GWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQNR 781 YN++K + VE+ LI+ EL AID +L +A T L W + + YI+ VR L++R Sbjct: 768 QGYNKLKQTLLEVEYPLIEDELRAIDEQLTAATTWLTWQDD-CWGYIERVRAATSELEHR 826 Query: 782 MQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQA 841 +++ ++N++ I Q M+ W+ L R+++++EA L+ + K+Y ++ G KI Sbjct: 827 VERTQKNVKVIQQTMRGWARCVLPPRREHRREAAFTLEDKGDLFTKKYKLIQGDGCKIHN 886 Query: 842 MVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFEI 901 +V EN +LF+A+ WK YV +IDD+V++ F Q I L F + N AP F+ Sbjct: 887 LVEENRKLFKANPSLDTWKIYVEFIDDIVVEGFFQAIMHDLDFFLKNTEKQLKPAPFFQA 946 Query: 902 RMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAK--DRMNYKMDLEDN 959 +M L + F P+L+ + GF L+E ++ + + ++ + R+A + NY+ D+++ Sbjct: 947 QMILLPPEIVFKPSLDREAGDGFYDLVEEMLCNSFRMSAQMNRIATHLEIKNYQNDMDNM 1006 Query: 960 TDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDT 1019 L E+R+E+ + V+N + + +++++ E ++YLW D+ EFMK+FL+YG AV+++++D Sbjct: 1007 LGLAEVRQEIMNRVVNVINKVLDFRNTLETHTYLWVDDRAEFMKHFLLYGHAVSSDEMDA 1066 Query: 1020 WTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRR 1079 ++ IP+ PPTL QF+EQID YE LY ++SK E+ +VF W + D +PFK +LL+ I++ Sbjct: 1067 HANEEIPEQPPTLEQFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLLTIIKK 1126 Query: 1080 WGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAAT 1139 W +MF+ HL V +SL +L+ F+K GL + L EGD+DGLV++M HL+ V+ RQ AT Sbjct: 1127 WSWMFQEHLLRFVIDSLNELQEFIKETDSGLQRELNEGDHDGLVDIMVHLLAVRSRQRAT 1186 Query: 1140 DNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSI 1199 D +FEPLK+TI LL++YG++MPE+++++L+ELPE W TKK+A V+ V+PL EV++ Sbjct: 1187 DELFEPLKETITLLESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEVTL 1246 Query: 1200 LRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNK----VFLLKGIMEALSKSGGLF 1255 +R+KC F+ KQ EFRERFR AP F+ NPY +L+K + L+ M + +S LF Sbjct: 1247 IRKKCILFDAKQAEFRERFRHYAPLGFNAENPYTALDKANEELEALEEEMLQMQESTRLF 1306 Query: 1256 EVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAK- 1314 EV +P+YKQ+K C +E++LLK LWD+++ V SI++W T+W+ I+VEQMD++ ++FAK Sbjct: 1307 EVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRRFAKA 1366 Query: 1315 ----DMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKF 1370 ++ SL+KE++ WDA+ GL+ TVK++ SLRA++ELQ+PA+R+RHW QLM+A VKF Sbjct: 1367 SSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQSPALRDRHWHQLMKAIGVKF 1426 Query: 1371 KMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRT 1430 ++E TTLADLL L LH ED+VR IVDKAVKE G EKV+ + TW+ M+F +E H RT Sbjct: 1427 LINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTWATMKFSYEVHYRT 1486 Query: 1431 GTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQR 1490 G +LKS E L ETLE NQVQLQ L+ SKY+ +F+++V SWQ KL+ AD VI W EVQR Sbjct: 1487 GIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQR 1546 Query: 1491 TWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLE 1550 TWSHLESIF+ SEDIR QL D++RFD ++ EFK LM K NV+EAT +P LY KL+ Sbjct: 1547 TWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVENVLEATCRPNLYEKLK 1606 Query: 1551 ALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLC 1610 L+ L++CEKALAEYLETKR+AFPRFYFVSSADLLDILS G P +V+ HL+KLFDS+ Sbjct: 1607 DLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQPKQVTCHLAKLFDSIA 1666 Query: 1611 KLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPE 1670 L+F D D +GMYSKE EY+ F EC+ G VE WL ++ M T+RH I E Sbjct: 1667 DLQFE-DNQDVSAHRAVGMYSKEKEYVPFQAECECVGHVETWLLQLEQTMQETVRHSITE 1725 Query: 1671 AVVTYEEKPREQWILDYPAQ-------IWWTTEVGLAFARLEEGYENAIKDYNKKQISQL 1723 A+V YEEKPRE WI D+PAQ IWWTT+VG+AF+RLEEGYE A+KD++KKQISQL Sbjct: 1726 AIVAYEEKPRELWIFDFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQL 1785 Query: 1724 NVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI-----VESSQAFTWQAQLRHRWD 1778 N LITLL+G L GDR KIMTICTIDVHARDVVAK+I V S QAFTW +QLRHRW+ Sbjct: 1786 NTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWE 1845 Query: 1779 EEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTG 1838 + ++HCF NICDAQ QY YEYLGN+PRLVITPLTDRCYITLTQSLHL M GAPAGPAGTG Sbjct: 1846 DTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTG 1905 Query: 1839 KTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVI 1898 KTETTKDLGRALG MVYVFNCSEQMDYKS GNIYKGL QTGAWGCFDEFNRISVEVLSV+ Sbjct: 1906 KTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVV 1965 Query: 1899 AVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAM 1958 AVQVK + DAIR +KK F FLGE I L P+VGIFITMNPGYAGR ELPENLKALFRPCAM Sbjct: 1966 AVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAM 2025 Query: 1959 VVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAG 2018 V PD ELICEI+L+AEGF++AR LARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAG Sbjct: 2026 VAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAG 2085 Query: 2019 SLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKII 2078 SLKRGD +R EDQVLMRALRDFN+PKIVTDD+PVF+GL+GDLFPALDVPR+R L+FE+++ Sbjct: 2086 SLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMV 2145 Query: 2079 KQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKP 2138 +QS +EL+LQ E+SF+LKVVQLEELL VRHSVF+VGNAG+GKS++L++LN+TY N+K+KP Sbjct: 2146 RQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKP 2205 Query: 2139 VAVDLDPKAVTCDELFGIINPVTREWKDG---------LFSTIMRDLANITHDGPKWIIL 2189 V DL+PKAVT DELFG I+ TREWKDG LFS+I+R+ AN+ HDGPKWI+L Sbjct: 2206 VWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVL 2265 Query: 2190 DGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILY 2249 DGDIDPMWIESLNTVMDDNKVLTLASNERI L MRL+FEI HLR+ATPATVSRAGILY Sbjct: 2266 DGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILY 2325 Query: 2250 INPADLGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQ 2309 +NP DLGWNP V+SWI+RR+ QSEKANL ILFDKY+P CLDKLR FK IT +PE +++Q Sbjct: 2326 VNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQ 2385 Query: 2310 TILYLLECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEF 2369 T+ LLECLLT + VP DSP+E+YE+YFVF C WAFGG + QDQ+ DY+ +FS+WW E Sbjct: 2386 TLCVLLECLLTPENVPSDSPKEVYEVYFVFACIWAFGGTLLQDQISDYQADFSRWWQKEM 2445 Query: 2370 KTIKFPSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDL 2429 K +KFPSQGTIFDYY+D TKK LPW DK+ F +DPDVPLQ LVHTTET R+RYFM+L Sbjct: 2446 KAVKFPSQGTIFDYYVDHKTKKLLPWADKIAQFTMDPDVPLQTVLVHTTETARLRYFMEL 2505 Query: 2430 LMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEK 2489 L+EK P+MLVGNAG GK+V +GD L SL+ D Y+V VPFN+YTTS LQ +LEKPLEK Sbjct: 2506 LLEKGKPLMLVGNAGVGKTVFVGDTLASLSED-YIVSRVPFNYYTTSTALQKILEKPLEK 2564 Query: 2490 KSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHN 2549 K+G NYGP G KKL+YFIDDMNMPEVD YGTV PHTLIRQH+D+ HWYDR K+ LK+IHN Sbjct: 2565 KAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEIHN 2624 Query: 2550 CQYVACMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQR 2609 CQYVACMNP GSFTI+ RLQRHF VFA +FP +AL TIY I + H ++ + +I R Sbjct: 2625 CQYVACMNPMVGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILR 2684 Query: 2610 ISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRL 2669 L+ A +A HQ + FLPTAIKFHY+FNLRDLSN+FQG+LF++ E LK PLDL+ L Sbjct: 2685 SGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHL 2744 Query: 2670 WLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPK 2729 WLHE+ RVYGDK++D+KD + R + + K+F+ + +L +P I+CHFA DP Sbjct: 2745 WLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHMLLQQPLIYCHFADRGKDPH 2804 Query: 2730 YVPVTDMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVG 2789 Y+PV D L +L + LD+YNE+NA M+LVLFEDA+ H+CRI+RIL +P+G ALLVGVG Sbjct: 2805 YMPVKDWEVLKTILTETLDNYNELNAAMHLVLFEDAMQHVCRISRILRTPQGCALLVGVG 2864 Query: 2790 GSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQV 2849 GSGKQSLSRLAAY+ GL+VFQITL +GYGI +L++DLA YI+ KN+P+VFL+TD+QV Sbjct: 2865 GSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAKNMPTVFLLTDAQV 2924 Query: 2850 AEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRR 2909 +E FLVLINDLLASGEIP LF +++V+ IIS + +V +LGM D+RE CWKFF+ +VR Sbjct: 2925 LDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHALGMVDSRENCWKFFMARVRL 2984 Query: 2910 QLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEV 2969 QLK+ILCFSPVG LRVRARKFPA+VNCTAIDWFH WP++ALVSVS RF+EET+GI Sbjct: 2985 QLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVSRRFIEETKGIEPVH 3044 Query: 2970 KASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIE 3029 K SIS FM++VHTTVNEMS Y ERR+NYTTPK+FLEQI L++NLL KK+ E+ K E Sbjct: 3045 KDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKE 3104 Query: 3030 RLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQ 3089 RL NG+ KL++TASQV DLKA+LA QEAEL+ +N A+ LI +G++ EKVS+EK IAD Sbjct: 3105 RLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSREKTIADA 3164 Query: 3090 EEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVN 3149 EE KV I V +KQ+ CE DL KAEPAL+AA AL+TLN+ NL+ELK+F +PP AV N Sbjct: 3165 EERKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTN 3224 Query: 3150 VTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKP-YQG 3208 VTAAVM+L AP G++PKD+SWKAAK+ MGKVD FL +L +DKEHIPE CLK Y Sbjct: 3225 VTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLK 3284 Query: 3209 NPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRI 3268 +P F+P IR+KS AAAGLC+W INI++FYEVYCDV PKRQAL +AN ELA A EKL I Sbjct: 3285 DPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAI 3344 Query: 3269 KNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESV 3328 + K+ +L+ NLS LT++FEKATAEK++CQ+E + TN+ I LANRLV L ++ IRW +S+ Sbjct: 3345 RKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSI 3404 Query: 3329 ENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPL 3388 ++F +Q TLCGDVLL +AFVSYVG FT++YR EL+ W+P++ KV IP+T GLD + Sbjct: 3405 KSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWVPFLQQ-KVSIPLTEGLDLI 3463 Query: 3389 SLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKA 3448 S+LTDDA +A WNN+GLPSDRMSTENA IL + ERWPL++D Q QGIKWIKNKY +LK Sbjct: 3464 SMLTDDATIAAWNNEGLPSDRMSTENAAILTHCERWPLVIDPQQQGIKWIKNKYGMDLKV 3523 Query: 3449 IRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYH 3508 LGQK +L+ IE A++ GD +LIEN+ ET+DPVLDPLLGRNTIKKGKYI+IGDKE E++ Sbjct: 3524 THLGQKGFLNAIETALAFGDVILIENLEETIDPVLDPLLGRNTIKKGKYIRIGDKECEFN 3583 Query: 3509 PKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLT 3568 FRLILHTK NPHYKPE+QAQ TL+NF VT DGLE QLLA VV+ ERPDLE+LK LT Sbjct: 3584 KNFRLILHTKLANPHYKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLT 3643 Query: 3569 KSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEV 3628 K QN+FKI LK LED LL RLSAA G+FL DT LVE LE TK T +EIE KV+EAK E Sbjct: 3644 KHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENER 3703 Query: 3629 KINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQR 3688 KINEARE YRP A RASLLYF++NDL KINP+YQFSLKAFNV+F +AI++ +++ R Sbjct: 3704 KINEARECYRPVAARASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGR 3763 Query: 3689 VINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGV 3748 + L + IT++V++YT++ LFE+DKL FL+Q+ FQ+L KKE++P+ELDFLLRF + Sbjct: 3764 ISILMESITHAVFLYTSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLRFTVEHTH 3823 Query: 3749 VSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKT 3808 +SPVDFL Q W IKA++ M+EF+ +D D+EGSAK+W+K VESE PEKE P+EWK K+ Sbjct: 3824 LSPVDFLTSQSWSAIKAIAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKS 3883 Query: 3809 ALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPG 3868 +QKL ++R +RPDRMTYA++NFVEEK+G+K+VE ++ K++EESSP+T IFFILSPG Sbjct: 3884 LIQKLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPG 3943 Query: 3869 VDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHC 3928 VD LKD+E LGK+LGFTID+GK HNVSLGQGQE VAE AL+ A++ GHWVILQ Sbjct: 3944 VDALKDLEILGKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQ------- 3996 Query: 3929 RNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEP 3988 N+HLVA+WLGTL+K LER+S GSH DYRVF+SAE AP+P+ HIIPQG+LEN+IKITNEP Sbjct: 3997 -NVHLVAKWLGTLEKLLERFSQGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEP 4055 Query: 3989 PTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPF 4048 PTGM ANLH AL F QDTLE+C+KE EFK +LF+LCYFHA VA R +FG QGW+RSYPF Sbjct: 4056 PTGMLANLHAALYNFDQDTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPF 4115 Query: 4049 NNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTE 4108 N GDLTI +VLYNYLEAN KVPW+DLRYLFGEIMYGGHITDDWDR+LCR YL E++ Sbjct: 4116 NPGDLTICASVLYNYLEANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPS 4175 Query: 4109 MLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRT 4168 + E +++LAPGF PP LDY GYH+YI+E LPPESP LYGLHPNAEI FLTVTS LFRT Sbjct: 4176 LTEDELMLAPGFAAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRT 4235 Query: 4169 VLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDIL 4228 +LEMQP+ SG G S EEK VK VLDDIL Sbjct: 4236 LLEMQPRNALSGDELGQSTEEK-----------------------------VKNVLDDIL 4266 Query: 4229 EKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTD 4288 EK+PE FNMAEIM K + ++PYV+V FQECERMNIL E+R SL++L+L LKGEL ++ Sbjct: 4267 EKLPEEFNMAEIMQKNSNRSPYVLVCFQECERMNILIREIRISLEQLDLSLKGELALSPA 4326 Query: 4289 VEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGF 4348 VE AL YDTVPDTW AYPS GLA W+ DLLLR REL+ WT D LP VWL+GF Sbjct: 4327 VEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAVVWLSGF 4386 Query: 4349 FNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWD 4408 FNPQSFLTAIMQ+MARKNEWPLDK L+ +VTKK +ED PPREG+Y++GLFMEGARWD Sbjct: 4387 FNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGAYLHGLFMEGARWD 4446 Query: 4409 TQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTK 4468 TQ G I EARLKEL MPVIF KA PVDR ETK YECPVY+T++RGP+Y+WTF LK++ Sbjct: 4447 TQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTKLRGPSYIWTFRLKSE 4506 Query: 4469 EKAAKWILAAVALLLQ 4484 EK AKW+LA VALLL+ Sbjct: 4507 EKTAKWVLAGVALLLE 4522 >gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] Length = 4471 Score = 2287 bits (5927), Expect = 0.0 Identities = 1445/4480 (32%), Positives = 2366/4480 (52%), Gaps = 333/4480 (7%) Query: 132 QVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMERIPSSLDNLLLH 191 Q++ ++ + V + + + +++G+ L +P + S++G + + P ++D L Sbjct: 194 QLIRDEFLMNVQKFASNIQRTMQQLEGEIKLEMP--IISVEGEVSDLAADPETVDIL--- 248 Query: 192 AIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQLNRPKVN 251 E +I+W +QI + AQ P E EFW R L +HEQ P V Sbjct: 249 --EQCVINWLNQISTAVE---AQLKKTPQGKGPLAEIEFWRERNATLSALHEQTKLPIVR 303 Query: 252 KIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQAD-FTMLPTF 310 K++++++++ S LQ V+T + + EA+D V +L + + + F ++ Sbjct: 304 KVLDVIKESDSMLVANLQPVFTELFKFHTEASDNVRFLSTVERYFKNITHGSGFHVVLDT 363 Query: 311 IAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLKGLQGEIEEVL 370 I ++ + +W S +YN R+I +++ +I E ++ + K + + Sbjct: 364 IPAMMSALRMVWIISRHYNKDERMIPLMERIAWEIAERVCRVVNLRTLFKENRASAQSKT 423 Query: 371 SGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFFQRIQTIEEL 430 + + K+ Y +D K+ +E WEF F R + Q + ++ Sbjct: 424 LEARNTLRLWKKAY--FD---TRAKIEASGRED-RWEFDRKRLFERTDYMATICQDLSDV 477 Query: 431 YKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLDPGDSNFDRDY 490 + EF + EL V G+ + D+V C+ D L N Sbjct: 478 LQILEEFYNIFGPELKAVTGD------PKRIDDVL--------CRVDGLVTPMENLT--- 520 Query: 491 ADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAEVAPRYSVMLE 550 FD S IKSS Y+ LI ++ + Sbjct: 521 ---------------------FDPFS-IKSSQFWKYVMDEFKIEVLI--------DIINK 550 Query: 551 LFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLEVSMKHLKHVE 610 +F L+N P ++KN PPVAG + W L R++ ++ + V+ Sbjct: 551 IFVQNLEN-----------------PPLYKNHPPVAGAIYWERSLFFRIKHTILRFQEVQ 593 Query: 611 HPVMS--GAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPLILRDAASN 668 + S G E K QKY E+ ++ + ++ Y+QW+ +Q + + L+ + + + Sbjct: 594 EILDSDRGQEVK---QKYLEVGRTMKEYEDRKYEQWMEVTEQVLPALMKKSLLTKSSIAT 650 Query: 669 ----------LIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLE 718 + +NFS AL ++ E KYL Q +P+ A ++ + + F ++ ++ Sbjct: 651 EEPSTLERGAVFAINFSPALREIINETKYLE-QLGFTVPELARNVALQEDKFLRYTAGIQ 709 Query: 719 LIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNL 778 ++ Y+ + + E +L+K + + S L WN G+ YI ++ + Sbjct: 710 RMLDHYHMLIGTLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIGDYITGCKQAIGKF 769 Query: 779 QNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALL------------DLDGRIANLN 826 ++ + + +N + IS + A LF+ K E L + + ++ Sbjct: 770 ESLVHQIHKNADDISSRLTLIEAINLFKYPAAKSEEELPGVKEFFEHIERERASDVDHMV 829 Query: 827 KRYAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLM 886 + Y A+ K++ +V + +A L+ Y Y + + + + I K+L Sbjct: 830 RWYLAIGPLLTKVEGLVV-HTNTGKAPKLA----SYYKYWEKKIYEVLTKLILKNLQSF- 883 Query: 887 DNMVIDESIAPLFEIRMELDEDGLTFNP-TLEVGSDRGFLALIEGLVNDIYNVARLI--- 942 N +I ++ PLF L + +P T E+ D+ + V + R + Sbjct: 884 -NSLILGNV-PLFHTETILTAPEIILHPNTNEI--DKMCFHCVRNCVEITKHFVRWMNGS 939 Query: 943 -----PRLAKDR----MNYKMDLEDNTDLIEMR----EEVSSLVINAMKEAEEYQDSFER 989 P+ ++ +N+ D+ N +IE + V ++IN MK Y ++R Sbjct: 940 CIECPPQKGEEEEVVIINFYNDISLNPQIIEQAVMIPQNVHRILINLMK----YLQKWKR 995 Query: 990 YSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEV 1049 Y LW + M+ F K PP +A + E++ Y K+ EV Sbjct: 996 YRPLWKLDKAIVMEKFAA-------------------KKPPCVA-YDEKLQFYSKIAYEV 1035 Query: 1050 SKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMG 1109 + K H ++ R + + W + L+ L +L M+ Sbjct: 1036 MRHPLIKDEH-CIRLQLRHLANTVQENAKSWVISLGKLLNESAKEELYNLHEEMEHLAKN 1094 Query: 1110 LTKPLKEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQ 1169 L K + L V+ + +++ + + + +++ + Y P+ + Sbjct: 1095 LRKI--PNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYNLFPPDAEKELVD 1152 Query: 1170 ELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDP 1229 ++ W+N ++ V+ + ++ + R + + ++ EF +RF E P S D Sbjct: 1153 KIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKRFYSEGPGSVGD- 1211 Query: 1230 NPYKSLNKVFLLKGIMEA-----------LSKSGGLFEVPVPDYKQLKACHREVRLLKEL 1278 L+K L G+ E L+ + LF++P+ Y +L +E+ L+ + Sbjct: 1212 ----DLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKEMSGLRMI 1267 Query: 1279 WDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKN 1338 +++ + + E+W T W ++NV+ + + F + +R L + ++ L+ +K Sbjct: 1268 YELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKMKA 1327 Query: 1339 VITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVD 1398 S+ + +L+N A+R+RHW++LM+ T V F+M+E TL ++ + LH + D + IV Sbjct: 1328 FKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTDVLNEIVT 1387 Query: 1399 KAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTM----MLKSSEVLVETLEDNQVQLQN 1454 A+KE +EK +K + TW M+F + + GT +L S + ++++L+DN LQ+ Sbjct: 1388 AAIKEVAIEKAVKEILDTWENMKFTVVKYCK-GTQERGYILGSVDEIIQSLDDNTFNLQS 1446 Query: 1455 LMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQ 1514 + S+++ FL+ V W++ LS VI IW VQR W +LESIFIG DIR+QLP +++ Sbjct: 1447 ISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGG-DIRSQLPEEAK 1505 Query: 1515 RFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAF 1574 +FD+I++ FK +M + +K P + P + L+ + + L C+K+L +YL++KR AF Sbjct: 1506 KFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAF 1565 Query: 1575 PRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKED 1634 PRF+F+S +LL IL + +DP+ V H+ K++D++ L+F + D K+ M S E Sbjct: 1566 PRFFFISDDELLSILGS-SDPLCVQEHMIKMYDNIASLRF--NDGDSGEKLVSAMISAEG 1622 Query: 1635 EYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTY-EEKPREQWILDYP----- 1688 E M F + G+VE W+ VL+ M T R EA+ Y E++ R W+L Y Sbjct: 1623 EVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWMLLYQGMVVL 1682 Query: 1689 --AQIWWTTEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRMKIMTIC 1746 +Q+WWT EV F + ++G + A+K+Y +K Q++ L+T + L+ DR K T+ Sbjct: 1683 AASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVL 1742 Query: 1747 TIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNT 1803 IDVHARD+V I + ++ F W++QLR WD E C Y YEY+G Sbjct: 1743 IIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLN 1802 Query: 1804 PRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQM 1863 RLVITPLTDR Y+TLTQ+L + +GGAPAGPAGTGKTETTKDL +ALG + V NC E M Sbjct: 1803 GRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGM 1862 Query: 1864 DYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEII 1923 DY++ G I+ GLAQ GAWGCFDEFNRI VLSVI+ Q++ +++A+ + F F G+ I Sbjct: 1863 DYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQEI 1922 Query: 1924 GLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLA 1983 L +GIFITMNPGYAGR ELPE++KALFRP ++VPD + ICEIML +EGFLEA+ LA Sbjct: 1923 SLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLA 1982 Query: 1984 RKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIP 2043 +K LY L +E LSKQ HYD+GLRA+KSVLV+AG LKRG ED VLMRALRD N+P Sbjct: 1983 KKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLP 2042 Query: 2044 KIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEEL 2103 K V +D+P+F+GLI DLFP LD PR R +F ++Q + E V KVVQ+ E Sbjct: 2043 KFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFET 2102 Query: 2104 LQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTRE 2163 + RH+ +VG GKS V+ +L + L L+PKAV+ EL+GI++P TR+ Sbjct: 2103 MLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYGILDPTTRD 2162 Query: 2164 WKDGLFSTIMRDLANITHDGP-KWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLN 2222 W DG+ S I R++ T K+I+ DGD+D +W+E++N+VMDDN++LTLA+ ERI L Sbjct: 2163 WTDGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQ 2222 Query: 2223 RTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFD 2282 L+FE+ L+ A+PATVSR G++Y++P +L + P W+ + + E+ NL LF+ Sbjct: 2223 AHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFE 2282 Query: 2283 KYLPTCLDKLRFG---------FKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRELY 2333 KY+P +D + G K I P ++ ++ + +L+ LL + D L Sbjct: 2283 KYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEGEIEDLD----LL 2338 Query: 2334 ELYFVFTCFWAFGGAMFQDQLVDY-----------RVEFSKWWINEFKTIKFPSQ-GTIF 2381 E YF+ + + G ++ +D + + V+ W N + P Q T++ Sbjct: 2339 ECYFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPG---ELPGQLPTLY 2395 Query: 2382 DYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVG 2441 D++ D +++PW+ VP + P+ LVHT +T R + ++ +++ PV+ VG Sbjct: 2396 DFHFDNKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVG 2455 Query: 2442 NAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTK 2501 +GT K+ + L++L+ + +V V F+ TTS +Q LE +EK++ YGPP K Sbjct: 2456 ESGTSKTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGK 2515 Query: 2502 KLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHK-LTLKDIHNCQYVACMNPTS 2560 +L+ F+DDMNMP VD+YGT P L++ ++ + YDR K L K I + ++A M Sbjct: 2516 RLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAG 2575 Query: 2561 GSFT-IDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAAL 2619 G +D R F VF V FP +E+L IY++IL H + + +I +S +L L Sbjct: 2576 GGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTS--TFHESIVAVSGKLTFCTL 2633 Query: 2620 ALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYG 2679 AL++ I PT KFHY+FNLRDLS +F GL+ + E +T +VR+W +E RV+ Sbjct: 2634 ALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFH 2693 Query: 2680 DKMVDEKDQETLHR-VTMASTKKFFDDLGDELLFAKPNIFCHFAQGI--GDPK-YVPVTD 2735 D+++ E D++ + + + + F DD+ E++ P +F F + G+P+ Y + D Sbjct: 2694 DRLISETDKQLVQQHIGSLVVEHFKDDV--EVVMRDPILFGDFQMALHEGEPRIYEDIQD 2751 Query: 2736 MAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQS 2795 L ++L+ YNE N MNLVLF+DA+ H+ R++RI+ RG+ALLVGVGGSGKQS Sbjct: 2752 YEAAKALFQEILEEYNESNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQS 2811 Query: 2796 LSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFL 2855 LSRLAA+ + +VF+I L +GY + DL + Y+K ++N +FL TD+ VAEE FL Sbjct: 2812 LSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFL 2871 Query: 2856 VLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVIL 2915 LIN++L SG +P LF E+E E+I+S + + GM +E+ W++F+ K L ++L Sbjct: 2872 ELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKSANNLHIVL 2931 Query: 2916 CFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISF 2975 SPVG LR R FP +VN T IDWF WP AL +V+ FL IP E ++ Sbjct: 2932 GMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVK 2991 Query: 2976 FMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGL 3035 + VH +V+ S+ +L RR NY TPK +L+ I Y LL +K +A+ +RL+ GL Sbjct: 2992 HVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGL 3051 Query: 3036 MKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVE 3095 KL+ Q+D+L KLA Q+ L +K+ + + L++ + + ++K +A+++ +++E Sbjct: 3052 DKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIE 3111 Query: 3096 VINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVM 3155 NK + ++ ET LA+ P L AA+ L L+K+++TE++SF PP V V ++ Sbjct: 3112 EQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECIL 3171 Query: 3156 ILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPE 3215 I+ K K+ +WK AK +M FL SL + D + I ++ +K K E Sbjct: 3172 IM-----KGYKELNWKTAKGVMSD-PNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTE 3225 Query: 3216 FIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAEL 3275 + + S A G+ + ++ + +V+ ++ PKR+ + + +L RI+N++A + Sbjct: 3226 EMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAI 3285 Query: 3276 NANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQG 3335 L L + +E A EK K Q+EA+ R ++ A++L+ GL SENIRW ++ + Sbjct: 3286 QKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRR 3345 Query: 3336 VTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDA 3395 V L GD LL +AF+SY G FT ++R+E++ + W I L+ IP++ SLLTDD Sbjct: 3346 VKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDI--LEREIPLSQPFRLESLLTDDV 3403 Query: 3396 DVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNK-YRSELKAIRLGQK 3454 +++ W +QGLP D +S +N + R+PL +D Q Q + WIK K ++ L+ Sbjct: 3404 EISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDP 3463 Query: 3455 SYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRN-TIKKGK-YIKIGDKEVEYHPKFR 3512 +L +E +I G L ++ E +DPV+D +L +N + +G+ +I +GDKEV+Y FR Sbjct: 3464 DFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFR 3523 Query: 3513 LILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQN 3572 L L+TK NP Y P + + +IN+ VT GLEDQLL+ +VA ER +LE+ + +L + + Sbjct: 3524 LYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETS 3583 Query: 3573 EFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINE 3632 E K +LK+LEDSLL L+ ++GN L + LV LE TK A+E+ EK+ A+ T + I+ Sbjct: 3584 ENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDR 3643 Query: 3633 ARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINL 3692 R+ YRPAA R ++L+F+L+++ +N +YQ+SL AF VF +++++ P + + +R+ N+ Sbjct: 3644 LRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNI 3703 Query: 3693 TDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPF---KAGVV 3749 D +T+S+Y + GLFER KL+F +T ++ + + ELDF L+ K+ Sbjct: 3704 MDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKSKRK 3763 Query: 3750 SPVDFLQHQGWGGIKALSEM--DEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNK 3807 P +L QGW I LSEM D F L D+E + W++ + ++ E+ P + N Sbjct: 3764 KPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQFPVPLGYDNN 3823 Query: 3808 -TALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILS 3866 T QKL ++RC R DR+ A+ ++V MG K+V+ + F +E+S+P + I FILS Sbjct: 3824 ITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPHSPIVFILS 3883 Query: 3867 PGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQ 3926 PG DP D+ L ++ GF +L +++GQGQE VA L+ A +G W++LQ Sbjct: 3884 PGSDPATDLMKLAERSGF--GGNRLKFLAMGQGQEKVALQLLETAVARGQWLMLQ----- 3936 Query: 3927 HCRNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITN 3986 N HL+ +WL L+K LER T H D+R++++ +P T P GIL+ ++K+ Sbjct: 3937 ---NCHLLVKWLKDLEKSLERI-TKPHPDFRLWLTTDP-----TKGFPIGILQKSLKVVT 3987 Query: 3987 EPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSY 4046 EPP G+ N+ + + L+ C FK +++ L +FHAVV ERRKFG GWN Y Sbjct: 3988 EPPNGLKLNMRATYFKISHEMLDQC-PHPAFKPLVYVLAFFHAVVQERRKFGKIGWNVYY 4046 Query: 4047 PFNNGDLTISINVLYNYL-----EANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYL 4101 FN D + + +L YL + +P++PW L+YL GE+MYGG D +DRR+ Y+ Sbjct: 4047 DFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYM 4106 Query: 4102 AEYIRTEMLEGDVLL------------APGFQIPPNLDYKGYHEYIDENLPPESPYLYGL 4149 EY+ GD + ++IP + + + E I+ +P ++GL Sbjct: 4107 DEYL------GDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGL 4160 Query: 4150 HPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELR 4209 HPNAEIG+ T + ++ +LE+QP+ +S +G+SR++ G Sbjct: 4161 HPNAEIGYYTQAARDMWAHLLELQPQTGES--SSGISRDDYIGQ---------------- 4202 Query: 4210 RGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAK-AAEKTPYVVVAFQECERMNILTNEM 4268 V +I K+P+ F++ ++ + +P VV QE ER N L M Sbjct: 4203 -------------VAKEIENKMPKVFDLDQVRKRLGTGLSPTSVVLLQELERFNKLVVRM 4249 Query: 4269 RRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIR 4328 +SL EL L GE+ ++ +++D++ +LF +P+ W A ++ L W L R Sbjct: 4250 TKSLAELQRALAGEVGMSNELDDVARSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFS 4309 Query: 4329 ELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTK-KNREDM 4387 + W T+ + P+ +WL+G P+S+LTA++Q+ RKN WPLD+ L +VTK ++ +++ Sbjct: 4310 QYMLWVTE-SEPSVMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDADEV 4368 Query: 4388 TAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYEC 4447 +G +V GL++EGA WD + G + +++ K L +P++ I I R++ +N + Sbjct: 4369 NERAGQGCFVSGLYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRT 4428 Query: 4448 PVYKTRIR----GPTYVWTFNLKTKEKAAKWILAAVALLL 4483 PVY T +R G V+ +L T + W+L V L L Sbjct: 4429 PVYTTSMRRNAMGVGLVFEADLFTTRHISHWVLQGVCLTL 4468 >gi|75677365 dynein heavy chain domain 3 [Homo sapiens] Length = 4427 Score = 2162 bits (5603), Expect = 0.0 Identities = 1363/4074 (33%), Positives = 2144/4074 (52%), Gaps = 237/4074 (5%) Query: 479 LDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLIL 538 LD ++ + DY F I+DL+ + F+ + LL L R I Sbjct: 446 LDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFELVRDVPHGVLLLDTFHRLASREAIK 505 Query: 539 AEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQER 598 + + LF++EL A + P + + +G+ +W L+ R Sbjct: 506 RTYDKKAVDLYMLFNSEL--------ALVNRERNKKWPDLEPYVAQYSGKARWVHILRRR 557 Query: 599 LEVSMKHLK--HVEHPVMSGAEAKLTYQKYDEMM-ELLRCHREKIYQQWVAGVDQDCHFN 655 ++ M L H + +G E+ TYQ+ + + EL+R K +Q+W + +D+DC Sbjct: 558 IDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVR----KTFQEWTSSLDKDCIRR 613 Query: 656 LGQPLI-LRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFV 714 L PL+ + + ++ VNF K+L+ + E+ Y + E P ++ E R Sbjct: 614 LDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWE-RLLFETPHYVVNVAERAEDLRILR 672 Query: 715 GNLELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQY-IQEVRE 773 NL L+ YN I ++ E L K + +D K+ L W +G + I E R Sbjct: 673 ENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAFFITECRI 732 Query: 774 ILHNLQNRMQKAKQNIEGISQAMKDWSANPL-----------FERKDNKKEALLDLDGRI 822 +Q + + K + I ++ S L E +++++E + ++ Sbjct: 733 HASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREHRAAVQQKL 792 Query: 823 ANLNKRYAAVRDAGVKIQAMVAENAELFRAD--TLSLPWKDYVIYIDDMVLDEFDQFIRK 880 NL++ + ++ + E+F+ D + W Y+I +D M+ D ++ Sbjct: 793 MNLHQ----------DVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKW 842 Query: 881 SLSFLMDNMVIDESIAP--LFEIRMELDED------GLTFNPTLEVGSDRGFLALIEGLV 932 SL L + D +P LF++ + L D + F+PTL+ + G+V Sbjct: 843 SLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQT---------LAGVV 893 Query: 933 NDIYN-----------VARLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAE 981 NDI N + ++ + R + +E + D+ +++ ++SS + N + Sbjct: 894 NDIGNHLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQ 953 Query: 982 EYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDS 1041 Y +++ Y +W N F+ + + P ++ F I Sbjct: 954 NYLKTWDMYREIWEINKDSFIHRY--------------------QRLNPPVSSFVADIAR 993 Query: 1042 YEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEA 1101 Y ++ V K E T ++ DC K +L+ W F L L +L Sbjct: 994 YTEVANNVQK-EETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELHT 1052 Query: 1102 FMKVARMGLTKPLKEGDYDG----LVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYG 1157 ++K +++P + + G LV+ + H + A + P+ + +L+ Y Sbjct: 1053 YLKENAEKISRPPQTLEELGVSLQLVDALKHDL------ANVETQIPPIHEQFAILEKYE 1106 Query: 1158 EEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRER 1217 + + + L L W ++ + K + + + L F+ K H E Sbjct: 1107 VPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDFKKKAHTLLED 1166 Query: 1218 FRREAPFSFSDPNPYKSLNKVFLLKGIMEALSKSG-------GLFEVPVPDYKQLKACHR 1270 F + F+ S+ +L+++ ++ ++ A+ + G+F++ P K L+ + Sbjct: 1167 FEFKGHFT-SNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQPPSKDLQNLEK 1225 Query: 1271 EVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMK--TWDA 1328 E+ L+++W++ + +WKT ++ + E M+ + + L KE K W+ Sbjct: 1226 ELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAKEYKDRNWEI 1285 Query: 1329 FVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKM-SEETTLADLLQLNLH 1387 + ++ ++ +S+L+NPA+RERHW Q+ Q +F SE TL +++L + Sbjct: 1286 IETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMD 1345 Query: 1388 SYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLED 1447 + +++ I A KE +E L+ + TW + + P+ G L+ +E + + LED Sbjct: 1346 QHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRGTEEVFQALED 1405 Query: 1448 NQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRT 1507 NQV L + S+++ F K+V W++ LS VI + VQR W +LE+IF+G EDIR Sbjct: 1406 NQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLG-EDIRK 1464 Query: 1508 QLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYL 1567 QLP +S FD +N +KA+M+ K N + +T PGL + L + L +K+L YL Sbjct: 1465 QLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYL 1524 Query: 1568 ETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGL 1627 ETKR FPRFYF+S+ DLL+IL +P V HL K FD++ L+ + + Sbjct: 1525 ETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAV 1584 Query: 1628 GMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEE--KPREQWIL 1685 GM+S + EY+ F L G VE WL V M TLR + + + R++W+ Sbjct: 1585 GMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVK 1644 Query: 1686 DYP-------AQIWWTTEVGLAFARLEEGYENAI-KDYNKKQISQLNVLITLLIGNLNAG 1737 ++ +QI WT +V +E + I K K Q+S LN + GNL Sbjct: 1645 EWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKI 1704 Query: 1738 DRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQ 1794 R+KI+ + TI++HARDV+ K+ + +F W +QLR W+++ C + Q Q Sbjct: 1705 MRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQ 1764 Query: 1795 YSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMV 1854 Y+YEYLGN+ RLVITPLTDRCY+TLT +LHL GG+P GPAGTGKTET KDLG+ALG V Sbjct: 1765 YNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYV 1824 Query: 1855 YVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKK 1914 V NCSE +DYKS G +Y GLAQTGAWGCFDEFNRI++EVLSV+A Q+ C+ A+ A Sbjct: 1825 IVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLT 1884 Query: 1915 AFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAE 1974 F+F G I L+ + GIFITMNPGYAGR ELPENLK++FRP AMVVPD LI EI+L E Sbjct: 1885 HFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGE 1944 Query: 1975 GFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLM 2034 GF ++LA+K TLY+L + LS+QDHYD+GLRA+ S+L AG +R P +++VL+ Sbjct: 1945 GFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLL 2004 Query: 2035 RALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFV 2094 ++RD NI K+ + D P+F ++ DLFP +++P + ++Q I ++ LQ+ + Sbjct: 2005 LSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTL 2064 Query: 2095 LKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRK-------PVAVDLDPKA 2147 KV QL E RHS IVG GSGK+ + L + +L R L+PKA Sbjct: 2065 TKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKA 2124 Query: 2148 VTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDD 2207 ++ EL+G + T EW DG+ S++MR KWI+ DG +D +WIE++N+VMDD Sbjct: 2125 LSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDD 2184 Query: 2208 NKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIER 2267 NKVLTL + ERI + + L+FE+ L A+PATVSR G++Y + ADLGW P V SW+E+ Sbjct: 2185 NKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEK 2244 Query: 2268 RKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPD 2327 R ++E L +F+K + L + K++ P+PE + I ++ L L T + Sbjct: 2245 RP-KAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLCKLYSALATPENGVNP 2303 Query: 2328 SPRELY----ELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDY 2383 + E Y E+ FVF+ W+ ++ D+ R++ ++ E + FP++ T+++Y Sbjct: 2304 ADGENYVTMVEMTFVFSMIWSVCASV--DEEGRKRIDS---YLREIEG-SFPNKDTVYEY 2357 Query: 2384 YIDPDTKKFLPWTDKVP-SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGN 2442 ++DP + + + DK+P S+ P+ P +V T +T+R Y + L+ P++LVG Sbjct: 2358 FVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGP 2417 Query: 2443 AGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKK 2502 GTGK+ + L+SL + + V V + TTS +Q ++E +EK++ Y P G K Sbjct: 2418 VGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKS 2477 Query: 2503 LVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGS 2562 ++ F+DD+NMP D +G+ P LIR +D+ WYDR K T+K I +A M P G Sbjct: 2478 MITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGGG 2537 Query: 2563 FTIDS-RLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALAL 2621 T+ S RL+ F + ++FP + + I+ T++ Q L + ++ I + + A L + Sbjct: 2538 RTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKL--QDFEEEVKPIGNVVTEATLDM 2595 Query: 2622 HQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDK 2681 + + FLPT K HY+FNLRD+S +FQG+L + + T + RLW+HE RV+ D+ Sbjct: 2596 YNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDR 2655 Query: 2682 MVDEKDQETLHRVTMASTKKFFDDLGDELLFAK-PNIFCHFAQGIGDPK-YVPVTDMAPL 2739 +VD D E + FFD L +K P IF F + +PK Y +TD+ L Sbjct: 2656 LVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDF---LKEPKVYEDLTDLTVL 2712 Query: 2740 NKLLVDVLDSYNEVNAV--MNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLS 2797 ++ L+ YN +V M LVLF +A+ HI RI R++ PRGN LLVG+GGSG+QSL+ Sbjct: 2713 KTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLA 2772 Query: 2798 RLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVL 2857 RLA+ I FQI + K Y + + D+ Y +A V+ + F+ D+Q+A+E FL Sbjct: 2773 RLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLED 2832 Query: 2858 INDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCF 2917 IN++L+SGE+P L+ DE E I S + Q + + ++ ++ + + IE+V+ L ++LC Sbjct: 2833 INNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCL 2892 Query: 2918 SPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETE-GIPWEVKASISFF 2976 SP+G R R++PA+VNCT I+WF EWP++AL+ V+ + L + G + ++ Sbjct: 2893 SPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQI 2952 Query: 2977 MSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLM 3036 +H +V + S+ L RR+NY TP +LE + Y+ LL +KR EL+A+ +L GL Sbjct: 2953 FVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLF 3012 Query: 3037 KLQSTASQVDDLKAKLAIQEAELKQ-KNESADQLIQVVGIEAEKVSKEKAI-ADQEEVKV 3094 K+ T +V + +L + ++ + + + + L+ +V + E ++KA+ A+ E++ V Sbjct: 3013 KIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAV 3072 Query: 3095 EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAV 3154 E I + DL +A PAL A AL++LNK ++ E+KS+G PP V V AV Sbjct: 3073 EEIKCQALADN--AQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAV 3130 Query: 3155 MILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDP 3214 MIL + +W AK +G+ F+ SL FDK++I + LK Y P F P Sbjct: 3131 MILRG------NEPTWAEAKRQLGE-QNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQP 3183 Query: 3215 EFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE 3274 + I S AA LC W + + +Y V PKR + A A+L E Q L+ + K+ E Sbjct: 3184 DIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLRE 3243 Query: 3275 LNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQ 3334 + L L +++ A+K + +++++ + A LV GLA E RW E+V+ Sbjct: 3244 VAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEED 3303 Query: 3335 GVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDD 3394 L GD LL +AF+SY+G F YR+E++ + WI I L+VP + +D + L + Sbjct: 3304 LGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAID--NFLCNP 3361 Query: 3395 ADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSE-LKAIRLGQ 3453 V WN QGLPSD STEN I+ RW L++D Q Q +KWIKN + LK I L Sbjct: 3362 TKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQM 3421 Query: 3454 KSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKG--KYIKIGDKEVEYHPKF 3511 YL ++E AI G +L++N+ E +DP L+P+L ++ + G ++IGDKEVEY+ F Sbjct: 3422 SDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNF 3481 Query: 3512 RLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQ 3571 R + TK NPHY PE A+ T++NF V GLE QLL VV KERP+LE+ K +L + Sbjct: 3482 RFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINI 3541 Query: 3572 NEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKIN 3631 K LKELED +L L+ A+G+ L D LV L T+K TA+E+ E++ ++ TE+ + Sbjct: 3542 AAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTD 3601 Query: 3632 EARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVIN 3691 ARE YRP A+RAS+L+F+LND+ I+P+YQFSL A+ +F +I ++ +N+++ R+ Sbjct: 3602 LAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDY 3661 Query: 3692 LTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVV-- 3749 L D TY+VY YT R LFER KL+F + ++L +LN E +F LR GVV Sbjct: 3662 LNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLR----GGVVLD 3717 Query: 3750 ------SPV-DFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPK 3802 +P +L W I L ++ F L + E + W + APEK + P Sbjct: 3718 REGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPG 3777 Query: 3803 EWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSI 3861 EW+N +Q++ +VR LR DR+ + + +F+ +GS+F+E + E+S+P + + Sbjct: 3778 EWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPL 3837 Query: 3862 FFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ 3921 FILSPGVDP + L + +G + H +SLGQGQ +A L +GHWV L Sbjct: 3838 VFILSPGVDPTSALLQLAEHMGMA---QRFHALSLGQGQAPIAARLLREGVTQGHWVFL- 3893 Query: 3922 VRGGQHCRNIHLVARWLGTLDKKLERYST-GSHEDYRVFISAEPAPSPETHIIPQGILEN 3980 N HL W+ LDK +E+ H +R+++S+ P P P IL+ Sbjct: 3894 -------ANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPD-----FPISILQV 3941 Query: 3981 AIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQ 4040 +IK+T EPP G+ AN+ + L ++ C+K ++K +LF+LC+FH+V+ ER+KF Sbjct: 3942 SIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQL 4001 Query: 4041 GWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTY 4100 GWN Y FN+ D +S N+L YL+ + PWD L+YL I YGGH+TDDWDRRL TY Sbjct: 4002 GWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTY 4061 Query: 4101 LAEYIRTEMLEGD---VLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGF 4157 + +Y + L + + IP + Y EYI + P +G HPNA++ Sbjct: 4062 INDYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVAS 4121 Query: 4158 LTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTG 4217 ++ LF T+L +QP+ T + AG G +REEK LEL Sbjct: 4122 QITEAQTLFDTLLSLQPQITPTRAG-GQTREEKV--------------LELAA------- 4159 Query: 4218 FQVKAVLDDILEKIPETFNMAEIM-AKAAEKTPYVVVAFQECERMNILTNEMRRSLKELN 4276 D+ +KIPE + A + +P VV QE +R N L + SL +L Sbjct: 4160 --------DVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLE 4211 Query: 4277 LGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTD 4336 G++G + ++T +E++ +F VP W +AYPS LAAW DL +R+ + E W + Sbjct: 4212 KGIQGLIVMSTSLEEIFNCIFDAHVPPLW-GKAYPSQKPLAAWTRDLAMRVEQFELWASR 4270 Query: 4337 FALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSY 4396 P WL+GF P FLTA++QS AR+N +D + V+ + ++ PP++G + Sbjct: 4271 ARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVW 4330 Query: 4397 VYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVY 4450 V GL++EGA WD + + EA +L MP I + + K +Y CP Y Sbjct: 4331 VRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCY 4384 Score = 107 bits (268), Expect = 2e-22 Identities = 74/315 (23%), Positives = 147/315 (46%), Gaps = 16/315 (5%) Query: 31 IGAEENVALFTEFFEKPDVQVLVLTLNAAGMIIPCLGFPQSLKSKGVYFIKTKSENINKD 90 + +E+ A+ F + P +L + ++ + LG P +++ VYFI+ I + Sbjct: 93 VWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVYFIRQAPVPITWE 152 Query: 91 NYRARLLYGDISPTPVDQLIAVVEEVLSSLLNQSENMAGWPQVVSEDIVKQVHRLKNEMF 150 N+ A + +G + + L+ ++ V + + + GWP+ + +H+ + Sbjct: 153 NFEATVQFGTVRGPYIPALLRLLGGVFAPQIFAN---TGWPESIRNHFASHLHKFLACLT 209 Query: 151 VMSGKIKGKTLLPIPEHLGSLDGTLESMERIPSSL--DNLLLHAIETTIIDWSHQIRDVL 208 K++G T+L IP E+M P + D L+ +ET++I W+ QI+++L Sbjct: 210 DTRYKLEGHTVLYIPA---------EAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML 260 Query: 209 SKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQLNRPKVNKIVEILEKAKSCYWPAL 268 S + L PL ++EF W R ++L I +QL + V + IL AKS Y Sbjct: 261 SAQETVETGENLGPLEEIEF--WRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPF 318 Query: 269 QNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQADFTMLPTFIAKVLDTICFIWATSEYY 328 + + +G ++A + +L L+ +E+ + + + K++ I IW S +Y Sbjct: 319 MKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHY 378 Query: 329 NTPARIIVILQEFCN 343 NT R+ + ++ C+ Sbjct: 379 NTRERLTSLFRKVCD 393 >gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] Length = 4158 Score = 1989 bits (5154), Expect = 0.0 Identities = 1240/3777 (32%), Positives = 1975/3777 (52%), Gaps = 257/3777 (6%) Query: 866 IDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFL 925 I + +E + K + +++ DES+ P+F + L L F P+LE FL Sbjct: 480 IQKWITEEKPEVPDKKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLE-----DFL 534 Query: 926 ALIEGLVNDIYNVARLIPRLAKDR---------MNYKMD-------------LEDNTDLI 963 I G VN N +P L D +N K++ ED+ + Sbjct: 535 DGILGAVNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFH 594 Query: 964 EMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDD 1023 + ++ + A + A Y +FE++ + +N E LD Sbjct: 595 TIISQIKETIQAAFESARIYAATFEKFQIFFKEN-----------------ESLDL---Q 634 Query: 1024 TIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW--- 1080 + P + F EQ++ Y K +++ T+ G L D R ++ L+ + R Sbjct: 635 ALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNV-GLLLIDTRLLREKLIPSPLRCLEV 693 Query: 1081 -GFMFKRHLSNHVTNSLADLE-AFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAA 1138 FM R V + + + A K+ + P +Y V + L +++ER + Sbjct: 694 LNFMLPRQSKKKVDAIIFEAQDAEYKLEFV----PTTTTEY---VHSLLFLDEIQERIES 746 Query: 1139 TDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVS 1198 ++ + Q +L++ Y P E +A K + V+ + + S Sbjct: 747 LEDEGNIVTQMYKLMEQYQVPTPPEDFAV-------FATMKPSIVAVRNAIDKSVGDRES 799 Query: 1199 ILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYK---SLNKVFL----LKGIMEALSKS 1251 +++ C E E DP +K+ L L+ ++ L K Sbjct: 800 SIKQFCVHLGSDLEELNNEVN-EVKLQAQDPQILDISADQDKIRLILNNLQSVLADLQKR 858 Query: 1252 GGL-------FEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ 1304 F+V V ++ L+ E++L + LWD + ++W +K+ ++ E Sbjct: 859 AFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLKSKFDCLDPEV 918 Query: 1305 MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ 1364 ++ K+AK + L+K + L V+ + L + +L+NP ++ RHW + Q Sbjct: 919 LNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQ 978 Query: 1365 ATQVKFKMSE-ETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQ 1423 +E TL L QL++ + E+++I +A E+ +E +LK ++ +W EF Sbjct: 979 TVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVEDSWKTTEFV 1038 Query: 1424 HEPHPRT-GTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVI 1482 PH + +L ++ + L+D+ + + L S+YL V WQ++L+ + + Sbjct: 1039 ILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQTL 1098 Query: 1483 SIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSK 1542 W QR W +LESIF + DI+ QLP +++ F +++ +K +M + PN + A ++ Sbjct: 1099 EEWLTCQRNWLYLESIF-NAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQ 1157 Query: 1543 PGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHL 1602 PGL + L +K L YLE+KR+ FPRFYF+S+ +LL+IL+ +P V HL Sbjct: 1158 PGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHL 1217 Query: 1603 SKLFDSLCKLKFRL---------DASDKPLKVG----LGMYSKEDEYMVFDQECDLSGQV 1649 K FDS+ KL+F L +P KV L M S E E + + G V Sbjct: 1218 RKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLGKGLKARGNV 1277 Query: 1650 EVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWIL-DYPAQ-------IWWTTEVGLAF 1701 E WL +V + M ++LR A+ Y+ K R W++ +P+Q I W ++ Sbjct: 1278 EEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPSQVILTVSQIMWCRDLTECL 1337 Query: 1702 ARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI- 1760 + A+K++ K +LN L ++ G+L R + + TIDVHARD+V +++ Sbjct: 1338 ETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTALITIDVHARDIVTELVQ 1397 Query: 1761 --VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYIT 1818 VE+ ++F WQ QLR+ WD + +C A + +Q Y YEYLG PRLVITPLTDRCY+ Sbjct: 1398 SKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLGACPRLVITPLTDRCYLC 1457 Query: 1819 LTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQT 1878 L +L L +GGAPAGPAGTGKTETTKDL +AL VFNCS+ +DYK G + GLAQ+ Sbjct: 1458 LMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQS 1517 Query: 1879 GAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPG 1938 GAW CFDEFNRI +EVLSVIA Q+ +++A AK F F G I L+ T FITMNPG Sbjct: 1518 GAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLVMTCAAFITMNPG 1577 Query: 1939 YAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLS 1998 YAGR ELP+NLKALFRP AM+VP++ LI E++L +EGF +++LARK +Y LC E LS Sbjct: 1578 YAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKMTQMYKLCSEQLS 1637 Query: 1999 KQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIG 2058 +QDHYD+G+RA+KSVLV+AGSLKR +P ED VL+RAL+D N+PK +TDD +F G+I Sbjct: 1638 QQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSNLPKFLTDDALLFSGIIS 1697 Query: 2059 DLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGS 2118 DLFP + +P + I + LQ E V KV+Q E + VRH V +VG G Sbjct: 1698 DLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGG 1757 Query: 2119 GKSQVLKSLNKTYQNLKRKPV---------AVDLDPKAVTCDELFGIINPVTREWKDGLF 2169 GK+ V + L +T NL++ + L+PK++T EL+G +N +T EWKDGL Sbjct: 1758 GKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLM 1817 Query: 2170 STIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVF 2229 + +R N T + KWII DG +D +WIE++NTV+DDNK+L LA++ERI L + ++F Sbjct: 1818 ALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLF 1877 Query: 2230 EISHLRTATPATVSRAGILYINPADLGWNPVVSSW---IERRKVQSEKANLMILFDKYLP 2286 E+ LR A+PATVSR G+++++P +L W P V +W I ++ + + ++ LF +Y+ Sbjct: 1878 EVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKLTEETQEYILNLFQRYVD 1937 Query: 2287 TCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEK-----TVPPDSPRELYELYFVFTC 2341 L + + P +I+ + T+ LLE L+ K + + FVF Sbjct: 1938 EGLHFINKKCSQAIPQVDISKVTTLCCLLESLILGKDGVNLAMEQTKLNTILCQTFVFCY 1997 Query: 2342 FWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVPS 2401 W+ GG + ++ + F + ++ + P+ G ++ ++D DTK+ PW +P+ Sbjct: 1998 LWSLGGNLTENYYDSFDT-FIRTQFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIPT 2056 Query: 2402 FELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESL-NT 2460 F+ + DVP LV TT+T+R Y M+ L+ V+ G G GKSV+ L + + Sbjct: 2057 FKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQES 2116 Query: 2461 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT 2520 Y+ + F+ T+SA Q ++E LE+K G PG K++V F+DD+NMP +D+YG+ Sbjct: 2117 AGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGS 2176 Query: 2521 VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYV-ACMNPTSGSFTIDSRLQRHFCVFAVS 2579 P L+RQ+ D +YDR+KL K+I + + AC P G + R RHF + + Sbjct: 2177 QPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLP 2236 Query: 2580 FPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYV 2639 P + +L I+ IL L+ A+++ +S +V A++ ++ K++ LPT K HYV Sbjct: 2237 MPSEHSLKQIFQAILNGFLS--DFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYV 2294 Query: 2640 FNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMAST 2699 FNLRDLS QG+L ++ + + RL+ HE +RV+ D++++ +D+ H + Sbjct: 2295 FNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMA 2354 Query: 2700 KKFFDDLGD-ELLFAKPNI---FCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVN- 2754 K F D E KP I F F D Y + D+ +L D LD YN N Sbjct: 2355 NKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNP 2414 Query: 2755 AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLK 2814 + LV F+DA+ H+ RI R++ RGNALLVGVGG+GKQSL+RLAA+I G QI L Sbjct: 2415 KEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELS 2474 Query: 2815 KGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMED 2874 +GY DL Y A V++ VFL TD+Q+ E+FL IN++L SGE+P LF +D Sbjct: 2475 RGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKD 2534 Query: 2875 EVENIISSMRPQVKSLGMND-TRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPA 2933 E+E ++++ RP+ K +G+++ R+ +++FI KVR++L ++LC SPVG R R R FP+ Sbjct: 2535 ELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPS 2594 Query: 2934 VVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLA 2993 +VNC IDWF +WP +AL+SVS F + + E+K + VH +V+ M+ Y Sbjct: 2595 LVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYN 2654 Query: 2994 TERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLA 3053 RR YTTP ++LE I LY ++L++KR ++++ +R++NGL KL T VD +K L+ Sbjct: 2655 ELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLS 2714 Query: 3054 IQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLA 3113 E L K+E + L++ + ++ E + + ++E +V + + DL Sbjct: 2715 ALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLD 2774 Query: 3114 KAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAA 3173 +A PAL AA +ALD+L+K +++E++ F PPD V+ V A+ IL + W +A Sbjct: 2775 EALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISIL------LNAKPDWPSA 2828 Query: 3174 KIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCIN 3233 K ++G FL L ++DKE+I L + Y NP F PE + S A +C W Sbjct: 2829 KQLLGD-SNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRA 2887 Query: 3234 IVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEK 3293 + + V V PKRQ L A AEL L + + ++ + L ++K EK Sbjct: 2888 MDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEK 2947 Query: 3294 IKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVG 3353 + T ++ A +L L E +RW ES++ F + + G+V + +A V+Y G Sbjct: 2948 ESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYG 3007 Query: 3354 YFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTE 3413 FT +YR L+E WI +L++PI + L +++L D ++ WN GLP D +STE Sbjct: 3008 AFTAQYRQSLIE-CWIQDCQSLEIPIDPSFSL--INILGDPYEIRQWNTDGLPRDLISTE 3064 Query: 3414 NATILGNTERWPLIVDAQLQGIKWIKNK-YRSELKAIRLGQKSYLDVIEQAISEGDTLLI 3472 N ++ RWPL++D Q Q +WI+NK +S LK I+L ++L ++E +I G +L+ Sbjct: 3065 NGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLL 3124 Query: 3473 ENIGETVDPVLDPLLGRNTIKKG--KYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQA 3530 E + ET+DP L+P+L + G I++GD +++Y FR + TK NPHY PE+ Sbjct: 3125 EELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCI 3184 Query: 3531 QCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLS 3590 + T+INF VT+ GLEDQLL+ VV E+P LE+ + L N K LK +E+ +L L Sbjct: 3185 KVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLF 3244 Query: 3591 AASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFI 3650 + GN L + L++ L+ +K T+ I+ ++ EA+ TE IN ARE YRP A + S++YF+ Sbjct: 3245 TSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFV 3304 Query: 3651 LNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFE 3710 + L++I+P+YQ+SLK F +F I+ + ++QR+ L ++ + Y+ +RGLFE Sbjct: 3305 IASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFE 3364 Query: 3711 RDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSP----VDFLQHQGWGGIKAL 3766 + KLI+ + +++ + L+ E +F LR P +L W L Sbjct: 3365 QHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDL 3424 Query: 3767 SE-MDEFKNLDSDIEG--------------SAKRWKKLVESEAPEKEIFPKE-------W 3804 E F L +I + ++W+ + + +K + ++ W Sbjct: 3425 EESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPW 3484 Query: 3805 K-NKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFF 3863 ++ KL +++C + +++ +A+ +FV E +G +F+E V+ Y++ S +T + F Sbjct: 3485 SAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVF 3544 Query: 3864 ILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVR 3923 ILS G DP+ + ++ G+ + ++ ++SLGQGQ +AE + A + G+WV LQ Sbjct: 3545 ILSTGSDPMGAFQRFARESGY---SERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQ-- 3599 Query: 3924 GGQHCRNIHLVARWLGTLDKKLERYS---TGSHEDYRVFISAEPAPSPETHIIPQGILEN 3980 N HL W+ +++ ++ ++ + + +R+F+S+ P ++ P +L+N Sbjct: 3600 ------NCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMP-----SNTFPVTVLQN 3648 Query: 3981 AIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQ 4040 ++K+TNEPP G+ AN+ +A T E +++ ++F +C+FHA++ ER+KFG Sbjct: 3649 SVKVTNEPPKGLRANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPL 3708 Query: 4041 GWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTY 4100 GWN Y FN+ D ++ L Y + K+PWD L Y+ GEI YGG +TD WD+R RT Sbjct: 3709 GWNICYEFNDSDRECALLNLKLYCKEG-KIPWDALIYITGEITYGGRVTDSWDQRCLRTI 3767 Query: 4101 LAEYIRTEMLEGDVLLA-PGFQIPPNLD-YKGYHEYIDENLP-PESPYLYGLHPNAEIGF 4157 L + E LE D + G P D + + +YI ENLP + P ++G+H NA + F Sbjct: 3768 LKRFFSPETLEEDYKYSESGIYFAPMADSLQEFKDYI-ENLPLIDDPEIFGMHENANLVF 3826 Query: 4158 LTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTG 4217 + L T+LE+QP+ S G G S +E L R E LE Sbjct: 3827 QYKETSTLINTILEVQPR--SSTGGEGKSNDEIVQELVASVQTRVPEKLE---------- 3874 Query: 4218 FQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNL 4277 +E E+ + ++ + T V QE +R N L + SL+ LN Sbjct: 3875 ----------MEGASESLFVKDLQGRLNSLT---TVLGQEVDRFNNLLKLIHTSLETLNK 3921 Query: 4278 GLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDF 4337 + G + ++ ++E + + + VP W AYPS+ L +W DL+LR ++ W Sbjct: 3922 AIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLKR- 3980 Query: 4338 ALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNRE------------ 4385 P + W++GFF PQ FLT +Q+ ARK P+D++ V R+ Sbjct: 3981 GQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQ 4040 Query: 4386 -------DMTAP-PREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVD 4437 DM P P +G V+G+FM+ +RWD + VI +A ++ P +PV+ + + Sbjct: 4041 FGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDALPGQMNPVLPVVHFEP-QQN 4099 Query: 4438 RMETKNIYECPVYKTRIRGPT---------YVWTFNLKTKEKAAKWILAAVALLLQV 4485 + +Y CP+YKT R T +V T L +K WI ALL Q+ Sbjct: 4100 YKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSALLCQL 4156 >gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] Length = 4265 Score = 1981 bits (5131), Expect = 0.0 Identities = 1170/3340 (35%), Positives = 1832/3340 (54%), Gaps = 192/3340 (5%) Query: 1254 LFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFA 1313 +F +P+ +Y +L +E + +LW E W I+ EQ++ + + Sbjct: 1002 IFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAF 1061 Query: 1314 KDMRSLDKEMKTWDAF--VGLD--NTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVK 1369 K M K+ K A V LD ++ + + L+NP +R RHW+ L + Sbjct: 1062 KTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININ 1121 Query: 1370 FKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPR 1429 + T A L++NL + + + + + A KE +E+ L ++ WS + F P+ Sbjct: 1122 VRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKA 1181 Query: 1430 TGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQ 1489 T T +LKS + + L+D+ V QN+ S Y F + + SW+ KL V+ W Q Sbjct: 1182 TDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQ 1241 Query: 1490 RTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKL 1549 R+W +LE IF SEDI QLP +S+R+ + + +K +M++A + V+ S + + L Sbjct: 1242 RSWLYLEPIF-SSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSL 1300 Query: 1550 EALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSL 1609 K L + +K L+EYLETKR AFPRFYF+S +LL+ILS DP V HL K F+++ Sbjct: 1301 RDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENI 1360 Query: 1610 CKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIP 1669 +L F+ D L++ MYS E E + S VE WL V M +++ I Sbjct: 1361 ARLLFQED-----LEI-THMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIE 1414 Query: 1670 EAVVTYEEKPREQWILDYPAQI-------WWTTEVGLAFARLEEGYENAIKDYNKKQISQ 1722 +A+ Y PR QW+L++P Q+ +WT EV A LE G N + Q Sbjct: 1415 KAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEA---LEAG--NLRSQLFPQLCQQ 1469 Query: 1723 LNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMIVE---SSQAFTWQAQLRHRWDE 1779 L+ L+ L+ G L+ R + + I+VHA+DVV+K+I E S F W +QLR+ W Sbjct: 1470 LSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTN 1529 Query: 1780 EKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGK 1839 + A +A+ Y YEYLGN+ RLVITPLTDRCY+TLT +LHL GGAPAGPAGTGK Sbjct: 1530 NDLYIRA--VNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGK 1587 Query: 1840 TETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIA 1899 TETTKDLG+AL VFNCS+Q+D+ + G +KGLA GAW CFDEFNRI +EVLSV+A Sbjct: 1588 TETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVA 1647 Query: 1900 VQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMV 1959 Q+ +Q A + + + F F G I L+P+ +FITMNPGYAGR ELP+NLKALFRP AM+ Sbjct: 1648 QQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMM 1707 Query: 1960 VPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGS 2019 VPD+ +I EI L + GF EA +LA+K T + L E LS QDHYD+G+RA+K+V+ AG+ Sbjct: 1708 VPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGN 1767 Query: 2020 LKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF---EK 2076 LKR +PS E+ + +RA+RD N+PK + +DL +F G++ DLFP + ++ D ++ ++ Sbjct: 1768 LKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTI---KEEDTDYGILDE 1824 Query: 2077 IIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKR 2136 I+++ L+ + F+ K +QL E VRH + +VG GSGKS + L +LK Sbjct: 1825 AIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKG 1884 Query: 2137 KPV-------AVD---LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKW 2186 +P AV+ L+PK++T +L+G + +T EW DG+FS+ +R A + KW Sbjct: 1885 QPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKW 1944 Query: 2187 IILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAG 2246 + DG +D +WIE++NTV+DDNK L L+S E I L M ++FE+ L A+PATVSR G Sbjct: 1945 YMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCG 2004 Query: 2247 ILYINPADLGWNPVVSSWIERRK--VQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPE 2304 ++Y+ P+ LG P + W+ + ++ + + LF +L + +R K++ Sbjct: 2005 MVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTN 2064 Query: 2305 ITVIQTILYLLECLLTE-------KTVPPDSPRELYEL---YFVFTCFWAFGGAMFQDQL 2354 + ++L LL+C K +P + + EL +F+F+ W+ G Sbjct: 2065 CNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSG- 2123 Query: 2355 VDYRVEFSKW----WINEFKTIKFPSQGTIFDYYIDP----------DTKK------FLP 2394 R FS W NE T+ FP +G +FDY ++ D ++ ++ Sbjct: 2124 ---RTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVK 2180 Query: 2395 WTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDK 2454 W D F + PD +V T +T+++ + +D+L+ PV+ +G GTGK++ + DK Sbjct: 2181 WMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDK 2240 Query: 2455 LESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPE 2514 L +Y+ + F+ T++ Q ++ L+K+ +GPP + ++FIDD+NMP Sbjct: 2241 LLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPA 2300 Query: 2515 VDKYGTVAPHTLIRQHMDHRHWYDRHKL-TLKDIHNCQYVACMNPTSGSF-TIDSRLQRH 2572 ++ YG P L+RQ MDH WYDR + K++ + +V M P G T+ RL RH Sbjct: 2301 LETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRH 2360 Query: 2573 FCVFAVSFPGQEALTTIYNTILTQHL-------AFRSV---SMAIQRISSQLVAAALALH 2622 F + + + + I++TIL L ++R + I + LV A + ++ Sbjct: 2361 FNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVY 2420 Query: 2623 QKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKM 2682 IT+ LPT K HY FNLRDLS +FQG+L + ++ + L+RLW HE RV+ D++ Sbjct: 2421 ATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRL 2480 Query: 2683 VDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPK-YVPVTDMAPLNK 2741 V+E+D+ ++ +++ F +P ++ F D K Y +T + + + Sbjct: 2481 VNEEDRSWFDQLLKRCMEQWEVTFNKVCPF-QPILYGDFMSPGSDVKSYELITSESKMMQ 2539 Query: 2742 LLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLA 2800 ++ + ++ YN++N A + LVLF DA++HICRI+R L GNALL+GVGGSG+ SL+RLA Sbjct: 2540 VIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLA 2599 Query: 2801 AYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLIND 2860 ++++ + FQI L K YG+ + + D+ +KA ++N+P FL +D+Q+ E FL IN+ Sbjct: 2600 SHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINN 2659 Query: 2861 LLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPV 2920 +L SG+IP L+ DE + I+S+MRP ++ G+ T+ + +VR + ++LC SP+ Sbjct: 2660 VLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMSPI 2719 Query: 2921 GSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEET---EGIPWEVKASISFFM 2977 G V R R R+FP++VNC IDWF+EWP +AL SV+ FL E E E++ I + Sbjct: 2720 GEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCV 2779 Query: 2978 SYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMK 3037 Y+H +V++ YLA R+NY TPK++LE + ++ L+ +K+ EL R+++GL K Sbjct: 2780 -YIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDK 2838 Query: 3038 LQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVI 3097 L T+ V ++ L L++ + ++ + ++ + + EE+K Sbjct: 2839 LLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEK 2898 Query: 3098 NKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMIL 3157 K + DL +A PAL AA +L LNKN++TE+++ PP V V AV I+ Sbjct: 2899 AKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIM 2958 Query: 3158 TA----------PGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQ 3207 PG K+ D W+ K ++ FL+SL KFDK++I + +KA +PY Sbjct: 2959 KGIKPKKVPGEKPGTKV--DDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYI 3016 Query: 3208 GNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSR 3267 N F P I S A +C W + +++ V V PKRQAL EA +L Q L Sbjct: 3017 DNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDE 3076 Query: 3268 IKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAES 3327 K ++ E+ ++ + + + + +K + + + + + + A +L+ GL+ E +RW E+ Sbjct: 3077 AKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQET 3136 Query: 3328 VENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDP 3387 VEN + + GDVL+ + FV+Y+G FT +YR L + W+ + + VP T+ Sbjct: 3137 VENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDS-WVKQLRSHNVPH--TSEPTL 3193 Query: 3388 LSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSE-L 3446 + L + + +W GLP+D +S EN I ++RW +D Q Q KWIKN + L Sbjct: 3194 IGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGL 3253 Query: 3447 KAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKK--GKYIKIGDKE 3504 +L + +L +E AI G L+EN+GE +DP L+P+L + T K+ +K+GD Sbjct: 3254 DVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTV 3313 Query: 3505 VEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLK 3564 + YH FR+ + TK NPHY PE+ + TLINF ++ GLEDQLL VVA+ERPDLE+ K Sbjct: 3314 IPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAK 3373 Query: 3565 ANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAK 3624 L S + + LK++ED +L RLS++ GN + D L++ LE +K A+EI+ KV A+ Sbjct: 3374 NQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAE 3433 Query: 3625 ITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANE 3684 TE I+ R Y P A R +L+F ++DL ++P+YQ+SL+ F +F I + A+ Sbjct: 3434 QTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADN 3493 Query: 3685 VKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPF 3744 +K+R+ N+ +TYS+Y R LFE+ KL+F + +++ + ++N E +LL Sbjct: 3494 LKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLL---- 3549 Query: 3745 KAGVVSPV------DFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKE 3798 G +S + D+L + W I ALS + F + SD ++ + +S P +E Sbjct: 3550 SGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHRE 3609 Query: 3799 IFPKEWKNKT-ALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSP 3857 P W QKL ++RCLR D++T A+++FV + +F+E ++ S +++S+ Sbjct: 3610 PLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNS 3669 Query: 3858 STSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHW 3917 +T + F+LSPG DP D+ +++ F+ KL +SLGQGQ AE + + E+G W Sbjct: 3670 TTPLIFVLSPGTDPAADLYKFAEEMKFS---KKLSAISLGQGQGPRAEAMMRSSIERGKW 3726 Query: 3918 VILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGS-HEDYRVFISAEPAPSPETHIIPQG 3976 V Q N HL W+ L++ +E + H D+R+++++ P+ P Sbjct: 3727 VFFQ--------NCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNK-----FPVS 3773 Query: 3977 ILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRK 4036 IL+N K+T EPP G+ ANL K+ +D L C K MEFK +L +LC FH ERRK Sbjct: 3774 ILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRK 3833 Query: 4037 FGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRL 4096 FG G+N Y F +GDL I I+ L +L+ +P+ L+Y GEI YGG +TDDWDRR Sbjct: 3834 FGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRC 3893 Query: 4097 CRTYLAEYIRTEMLEGDVLLAPG---FQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNA 4153 L ++ ++L + + QIPP D GY YI + P ++GLH NA Sbjct: 3894 IMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNA 3953 Query: 4154 EIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGC 4213 I F + L T++++QPK + +G+ REE Sbjct: 3954 NITFAQNETFALLGTIIQLQPKSSSAGSQ---GREEI----------------------- 3987 Query: 4214 PGTGFQVKAVLDDILEKIPETFNMAEIMAK--AAEKTPYVVVAFQECERMNILTNEMRRS 4271 V+ V +IL K+PE N+ +MAK + V QE R N L + ++ Sbjct: 3988 ------VEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQT 4041 Query: 4272 LKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELE 4331 L++L LKG + +++ +E ++ +L+ +TVP+ W A+AYPS+ L++W DLL R+ L+ Sbjct: 4042 LQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQ 4101 Query: 4332 AWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPP 4391 AW D +P W++GFF PQ+FLT +Q+ ARK +D + +V + ++T P Sbjct: 4102 AWIQD-GIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRP 4160 Query: 4392 REGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYK 4451 + G Y++GLF+EGARWD + +AE++ KEL M VI++ P + + ++ Y CP+YK Sbjct: 4161 QVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYK 4220 Query: 4452 TRIRGPT---------YVWTFNLKTKEKAAKWILAAVALL 4482 T R T YV + T + WI VAL+ Sbjct: 4221 TLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALI 4260 >gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] Length = 4024 Score = 1946 bits (5040), Expect = 0.0 Identities = 1225/3730 (32%), Positives = 1949/3730 (52%), Gaps = 248/3730 (6%) Query: 897 PLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRL-----AKDRMN 951 P F +R+ LD D + F P L D FL + + ++ + V R+ +L +K + Sbjct: 400 PGFIMRLILDNDTIKFEPELSDYIDI-FLNVYDVMIKAVSFVPRVETKLYSKWESKSKPT 458 Query: 952 YKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCA 1011 + N + +E++ +++ E+ +++Y +L T + + NFL Sbjct: 459 TLKPIILNEIVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFL----- 513 Query: 1012 VTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQ 1071 AE+ + + ++I Y+KL EE+ + G + C + Sbjct: 514 --AEN-------------HSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIR 558 Query: 1072 ALLSTI-----RRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVM 1126 AL+ + MF+ H V L D F ++A L+ P + L+E+ Sbjct: 559 ALVKRADIICGKLLAKMFRDH--QEVNTRLCD--EFERIAEKALSTPPNTAE---LMEMK 611 Query: 1127 GHLMKVKERQAAT-DNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQV 1185 ++ KV+ + K + L Y P ++ L + + Sbjct: 612 AYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHR 671 Query: 1186 KLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSD-PNPYKSLNKVFLLKGI 1244 K+ ++ + L+ +C++F + + ++ E +SF D + + L K +L G Sbjct: 672 KIIKEKIEQYQEG-LKLRCERFVEELESYAKQ--SEEFYSFGDLQDVQRYLKKAQILNGK 728 Query: 1245 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKE-------LWDMVVVVNTSIEDWKTTKW 1297 ++ + F + L + + + + +++ L++ V +++ W + Sbjct: 729 LDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPY 788 Query: 1298 KDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRA----VSELQNPA 1353 +N +Q++ D + + + L+K + + V++ + + + + NP Sbjct: 789 HKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPG 848 Query: 1354 IRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKAL 1413 +R RHW+ + + S+++T++ L +NL Y D I + A KE +EK ++ + Sbjct: 849 LRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKM 908 Query: 1414 DSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQ 1473 + W +EF + TGT +L S + + L+D+ ++ Q + S ++ + K++ W+ Sbjct: 909 ITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEG 968 Query: 1474 KLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKT 1533 KL ++ W +VQ TW +LE IF S DI +Q+P + +RF +++ ++ +M ++ Sbjct: 969 KLLLLQEILDEWLKVQATWLYLEPIF-SSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQD 1027 Query: 1534 PNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGN 1593 +V+ + + +L+ + L + K L EYLE KRL FPRF+F+S+ +LL+ILS Sbjct: 1028 KHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETK 1087 Query: 1594 DPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWL 1653 DP V HL K F+ + K++F +K G + E + GQVE WL Sbjct: 1088 DPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEG---EVVELIEIISTAKARGQVEKWL 1144 Query: 1654 NRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYP-------AQIWWTTEVGLAFARLEE 1706 + M +++ +A Y + R W+ D+P +QI+WT EV A + Sbjct: 1145 VELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIK 1204 Query: 1707 GYENAIKDYNKKQISQLNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI---VES 1763 E +K N+ Q++ ++TL+ G L+ +R+ + + +DVHARDV++ ++ + Sbjct: 1205 ALEQYLKTCNR----QIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISD 1260 Query: 1764 SQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSL 1823 F W +QLR+ W E H + +A ++Y YEYLGN+PRLVITPLTDRCY TL +L Sbjct: 1261 DSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGAL 1318 Query: 1824 HLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGC 1883 HL +GGAP GPAGTGKTETTKDL +A+ VFNCS+ +DY + G +KGL GAW C Sbjct: 1319 HLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWAC 1378 Query: 1884 FDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRA 1943 FDEFNRI +EVLSV+A Q+ +Q I A F G + L PT +FITMNPGYAGR+ Sbjct: 1379 FDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRS 1438 Query: 1944 ELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHY 2003 ELP+NLKALFR AM+VPD+ +I EI+L + GF+ AR L+ K + Y LC E LS Q HY Sbjct: 1439 ELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHY 1498 Query: 2004 DWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPA 2063 D+G+RA+KSVL AG+LK P+ E+ +L+R++ D N+PK ++ DLP+F G+ DLFP Sbjct: 1499 DYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPG 1558 Query: 2064 LDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQV 2123 + +P+ + IK + + LQ F K++Q+ E++ VRH IVG GK+ Sbjct: 1559 VKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSA 1618 Query: 2124 LKSLNKTYQNLKRKPVAVD-------LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDL 2176 + L ++ K + + L+PK+VT +L+G + V+ EW DG+ + R Sbjct: 1619 YRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAF 1678 Query: 2177 ANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRT 2236 A+ KW+I DG +D +WIE++NTV+DDNK L L S E I ++ M L+FE L Sbjct: 1679 ASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEV 1738 Query: 2237 ATPATVSRAGILYINPADLGWNPVVSSWIERRKVQ---SEKANLMILFDKYLPTCLDKLR 2293 A+PATVSR G++Y+ P LGW P++ SW+ +K +M LFD+ +P ++ +R Sbjct: 1739 ASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIR 1798 Query: 2294 FGFKKITPVPEITVIQTILYLLECLL----TEKTVPPDSPRELYEL---YFVFTCFWAFG 2346 K+++P + ++++++ L++C + E + + RE Y L F+F+ W+ G Sbjct: 1799 KHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVG 1858 Query: 2347 GAMFQDQLVDY--------RVEFSKWWINEFK-------------TIKFPSQGTIFDY-Y 2384 + D + + S N FK T+ FP +GTI+DY + Sbjct: 1859 ASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQF 1918 Query: 2385 IDPDTKKFLPWTDKVPSFELDP-DVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNA 2443 + K+ PW K+ P DV +V T +TIR M+LL P + VG Sbjct: 1919 VTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPT 1978 Query: 2444 GTGKSVLMGD-KLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKK 2502 GTGKSV + + L LN + Y + F+ TT+A Q ++ L+K+ +GPP K+ Sbjct: 1979 GTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKR 2038 Query: 2503 LVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGS 2562 +V F+DD+NMP + YG P L+RQ +DH +WYD ++ + + Q + M P G Sbjct: 2039 MVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGG 2098 Query: 2563 FT-IDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAF-RSVSMAIQRISSQLVAAALA 2620 + R RHF + ++ +++ TI++ ILT HL +++Q+V + Sbjct: 2099 RNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMT 2158 Query: 2621 LHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGD 2680 L+++ LPT K HY+FNLRD S + QG+ S E +T + RLW+HE RVY D Sbjct: 2159 LYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYD 2218 Query: 2681 KMVDEKDQETLHRVTMASTKKF----FDDLGDELLF----------AKPNIFCHFAQGIG 2726 +++D D+ L + + F +L L F + +FC F Sbjct: 2219 RLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDF----H 2274 Query: 2727 DPK-----YVPVTDMAPLNKLLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPR 2780 DPK Y + D+ L ++ L+ YN ++ MNLVLF A+ HI RI+RIL+ PR Sbjct: 2275 DPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPR 2334 Query: 2781 GNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPS 2840 +ALLVGVGGSG+QS++RLAA+++ VFQ+ + KGY + DL K A + Sbjct: 2335 SHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQG 2394 Query: 2841 VFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSM----RPQVKSLGMNDTR 2896 VFL TD+Q+ EE FL +++LL +GEIP LF DE + I M R + K+ + + Sbjct: 2395 VFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSP 2454 Query: 2897 ETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSA 2956 + FI+ R QL V+L SP+G R R RKFPA+VNC IDWF WPEDAL +V++ Sbjct: 2455 IALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVAS 2514 Query: 2957 RFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNL 3016 RFLEE E + E++ HT+ ++S+ + +RYNY TP ++LE I ++ L Sbjct: 2515 RFLEEIE-MSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLL 2573 Query: 3017 LAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIE 3076 L KKR+E++ +R E GL KL S +SQV ++ +L +LK ++ D+++ ++ E Sbjct: 2574 LEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKE 2633 Query: 3077 AEKVSK-EKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLT 3135 + +V+K EK + E + E + K + C+ DLA A P L +A ALDTL ++T Sbjct: 2634 SVEVAKTEKIVKADETIANEQAMASKAIKDE-CDADLAGALPILESALAALDTLTAQDIT 2692 Query: 3136 ELKSFGSPPDAVVNVTAAVMIL-----------TAPGGKIPKDKSWKAAKIMMGKVDTFL 3184 +KS SPP V V A+ IL T G KI + W AK ++G + FL Sbjct: 2693 VVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKI--EDFWGPAKRLLGDM-RFL 2749 Query: 3185 DSLKKFDKEHIPEACLKAF-KPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCD 3243 SL ++DK++IP A + K Y NP F PE IR+ STAA GLC W I + + +V Sbjct: 2750 QSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKI 2809 Query: 3244 VAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADAT 3303 VAPK+ L A EL A + L + + + E+ L+ L E +K + + D Sbjct: 2810 VAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLC 2869 Query: 3304 NRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNEL 3363 ++ + A +L+GGL E RW+ + + L GD+L+ S V+Y+G FT YR Sbjct: 2870 SKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQN- 2928 Query: 3364 MEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTER 3423 K W IP ++ + L + + TWN GLPSD S +N I+ N R Sbjct: 2929 QTKEWTTLCKGR--DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARR 2986 Query: 3424 WPLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPV 3482 WPL++D Q Q KWIKN + + L I+L + Y+ +E I G +L+EN+GE +DP+ Sbjct: 2987 WPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPI 3046 Query: 3483 LDPLLGRNTIKKG--KYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT 3540 L+PLL + T K+G I++GD +EY P FR + TK NPHY PE + TL+NF++T Sbjct: 3047 LEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMIT 3106 Query: 3541 RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT 3600 +G++DQLL VVA+ERPDLE+ K L E K LKE+ED +L LS++ GN L D Sbjct: 3107 PEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDE 3166 Query: 3601 ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV 3660 ++ L ++K A+EI +K A+ TE KI+ R YRP A +S+L+F L DL I P+ Sbjct: 3167 TAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPM 3226 Query: 3661 YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV 3720 YQ+SL F +F +I+ + + + +R+ L D TYS+Y+ R LFE+DKL+F + Sbjct: 3227 YQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCL 3286 Query: 3721 TFQVLSMKKELNPVELDFLLRFPFKAGVVSP----VDFLQHQGWGGIKALSEMDEFKNLD 3776 T +L ++ +N E FLL G+ +P +L + W I L ++ FK + Sbjct: 3287 TINLLLHERAINKAEWRFLLTGGI--GLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIR 3344 Query: 3777 SDIEGSAKRWKKLVESEAPEKEIFPKEWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEK 3835 + WKK+ +S P E+FP+EW++K Q++ ++RCLRPD++ ++ F+ + Sbjct: 3345 REFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINR 3404 Query: 3836 MGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVS 3895 +G F+E + +K++ +S+ + F+LSPG DP+ + G+ KL ++S Sbjct: 3405 LGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGY--GGSKLSSLS 3462 Query: 3896 LGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGS-HE 3954 LGQGQ +A L+ A ++G WV+LQ N HL W+ TL+K E S S H Sbjct: 3463 LGQGQGPIAMKMLEKAVKEGTWVVLQ--------NCHLATSWMPTLEKVCEELSPESTHP 3514 Query: 3955 DYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKAL---DLFTQDTLEMC 4011 D+R+++++ P+P+ P +L+N +K+TNE P G+ AN+ ++ + + C Sbjct: 3515 DFRMWLTSYPSPN-----FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSC 3569 Query: 4012 TKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVP 4071 K EFK +L+ LC+FHA+V ERRKFG GWN Y FN DL IS+ L+ +L ++P Sbjct: 3570 KKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELP 3629 Query: 4072 WDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG---FQIPPNLDY 4128 ++ LRY+ GE YGG +TDDWDRR R+ L ++ E++E + +PP+ D+ Sbjct: 3630 YEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDH 3689 Query: 4129 KGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSRE 4188 K Y EY +P ++G++ NA+I ++ LF +L Q + +GAG S E Sbjct: 3690 KSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSR--SAGAGAKSSDE 3747 Query: 4189 EKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKT 4248 V V DIL K+P F++ M + T Sbjct: 3748 ------------------------------VVNEVASDILGKLPNNFDIEAAMRR--YPT 3775 Query: 4249 PYV----VVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDT 4304 Y V QE R N L +R S + +KG ++TD+E++ +++ +P+ Sbjct: 3776 TYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEM 3835 Query: 4305 WVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMAR 4364 W+ ++YPS+ L ++ D L R++ L+ W + P WL+GFF Q+FLT Q+ AR Sbjct: 3836 WMGKSYPSLKPLGSYVNDFLARLKFLQQW-YEVGPPPVFWLSGFFFTQAFLTGAQQNYAR 3894 Query: 4365 KNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTP 4424 K P+D + EV + ++ PP +G +++GLF++GA W+ + +AE+ K L Sbjct: 3895 KYTIPIDLLGFDYEVMED--KEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYD 3952 Query: 4425 AMPVIFIKAIPVDRMETKNIYECPVYKTRIR---------GPTYVWTFNLKTKEKAAKWI 4475 +PV+++K + + Y P+YKT R +V L + + WI Sbjct: 3953 TVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWI 4012 Query: 4476 LAAVALLLQV 4485 VALL Q+ Sbjct: 4013 GRGVALLCQL 4022 >gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] Length = 4624 Score = 1921 bits (4977), Expect = 0.0 Identities = 1188/3643 (32%), Positives = 1930/3643 (52%), Gaps = 188/3643 (5%) Query: 929 EGLVNDIYNVARLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFE 988 E + D +A + + NY ++ +N +++++ +S+++ + KE D F+ Sbjct: 1083 ENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKEVITSMDCFK 1142 Query: 989 RYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEE 1048 RY+++W +E +K F+ P L++F+ QI ++ L +E Sbjct: 1143 RYNHIWQKGKEEAIKTFITQS--------------------PLLSEFESQILYFQNLEQE 1182 Query: 1049 VSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARM 1108 ++ E V G + K AL + + W + RH + + + ++ ++ Sbjct: 1183 IN-AEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEFNK 1241 Query: 1109 GLTKPLKEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKL 1168 L +P+K D D + M L +++E Q + D P++++ LL YG + E K+ Sbjct: 1242 KLNRPIK--DLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKV 1299 Query: 1169 QELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSD 1228 L W A +V+ + LQ + L + F H+F + P + S Sbjct: 1300 DTLHYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMA-SG 1358 Query: 1229 PNPYKSLNKVFLLKGIMEALSK-----SGG--LFEVPVPDYKQLKACHREVRLLKELWDM 1281 P ++ +++ + + + + + +GG LF +P Y QL +++ LL++++ + Sbjct: 1359 LKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTL 1418 Query: 1282 VVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVIT 1341 V ++ + W ++N+E+++ + +F R L + +K W AF+ L + + Sbjct: 1419 YNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSE 1478 Query: 1342 SLRAVSELQNPAIRERHWQQLMQATQVKFKMSEET-TLADLLQLNLHSYEDEVRNIVDKA 1400 + + + A+ ERHW+++ T + E+ L ++++ L Y++E+ +I A Sbjct: 1479 CCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISA 1538 Query: 1401 VKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLK--SSEVLVETLEDNQVQLQNLMMS 1458 VKE +E+ LK + + W F G ++L+ S+ ++ +ED+ + L +L+ + Sbjct: 1539 VKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSLMLLGSLLSN 1598 Query: 1459 KYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDD 1518 +Y F ++ W Q LS + +I W VQ W +LE++F+G DI QLP +++RF + Sbjct: 1599 RYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGG-DIAKQLPKEAKRFSN 1657 Query: 1519 INQEFKALMEDAVKTPNVVEA-TSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRF 1577 I++ + +M A + P+VV+ L L L L IC+K+L YLE KRL FPRF Sbjct: 1658 IDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRF 1717 Query: 1578 YFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYM 1637 +FVS LL+IL +D + HL +FD++ +KF D+ L + S+E E + Sbjct: 1718 FFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRILSIS----SQEGETI 1773 Query: 1638 VFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPRE--QWILDYPAQIW--- 1692 D+ G VEVWLN +L+ S+L I +A +E + +++ +PAQ+ Sbjct: 1774 ELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSSFPAQVGLLG 1833 Query: 1693 ----WT--TEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRMKIMTIC 1746 WT +E L A+ ++ ++ N+ + LN LI + +L++ +R+K T+ Sbjct: 1834 IQMIWTRDSEEALRNAKFDK---KIMQKTNQAFLELLNTLIDVTTRDLSSTERVKYETLI 1890 Query: 1747 TIDVHARDV---VAKMIVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNT 1803 TI VH RD+ + M ++S F W Q R ++E+ +I D Y E+LG T Sbjct: 1891 TIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCT 1950 Query: 1804 PRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQM 1863 RLVITPLTDRCYITL Q+L + MGGAPAGPAGTGKTETTKD+GR LG V VFNCS+QM Sbjct: 1951 DRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQM 2010 Query: 1864 DYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFL-GEI 1922 D++ G I+KGLAQ+G+WGCFDEFNRI + VLSV A Q+ + + KK+F F G+ Sbjct: 2011 DFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDN 2070 Query: 1923 IGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLL 1982 + + P G+F+TMNPGYAGR ELPENLK FR AM+VPD ++I + L + GF++ +L Sbjct: 2071 VTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVL 2130 Query: 1983 ARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNI 2042 ARKF TLY LC+E LSKQ HYD+GLR I SVL G+ KR +P E ++MR LRD N+ Sbjct: 2131 ARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNL 2190 Query: 2043 PKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEE 2102 K++ +D P+F+ LI DLFP + + + E I + + E L + LKV+QL E Sbjct: 2191 SKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFE 2250 Query: 2103 LLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTR 2162 +VRH + +G +G+GK+ + +L + + + + ++PKA+T ++FG ++ T Sbjct: 2251 TQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFGRLDVATN 2310 Query: 2163 EWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLN 2222 +W DG+FST+ R WIILDG +D +WIE+LN+V+DDNK LTLA+ +RIP+ Sbjct: 2311 DWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMA 2370 Query: 2223 RTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFD 2282 +++FE ++ A+PATVSR G+++++ + L W+P++ ++++R Q + IL Sbjct: 2371 PNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAE----ILRQ 2426 Query: 2283 KYLPTCLDKLRFGFKKIT---PVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVF 2339 Y + D RF + + V E VI + +L+ L+ K + + FVF Sbjct: 2427 LYTESFPDLYRFCIQNLEYKMEVLEAFVITQSINMLQGLIPLKEQGGEVSQAHLGRLFVF 2486 Query: 2340 TCFWAFGGAMFQDQLVDYRVEFSKWWINE-FKTIKFPSQG----TIFDYYIDPDTKKFLP 2394 W+ G A+ +D R W + T++ P T FDYY+ PD + Sbjct: 2487 ALLWSAGAALE----LDGRRRLELWLRSRPTGTLELPPPAGPGDTAFDYYVAPDGT-WTH 2541 Query: 2395 WTDKVPSFELDPDVPLQ--ASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMG 2452 W + + D + + LV + +R + + + ++ V+L+G GT K+V++ Sbjct: 2542 WNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIK 2601 Query: 2453 DKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNM 2512 + + + ++++++ F+ TT M Q +E ++K+ G YGPP KK+ FIDD+NM Sbjct: 2602 GFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNM 2661 Query: 2513 PEVDKYGTVAPHTLIRQHMDHRHWYDRHKL-TLKDIHNCQYVACM-NPTSGSFTIDSRLQ 2570 P ++++G + ++RQ M+ +Y+ K I + Q++A M +P G I RL+ Sbjct: 2662 PIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLK 2721 Query: 2571 RHFCVFAVSFPGQEALTTIYNTILTQHLAF-RSVSMAIQRISSQLVAAALALHQKITATF 2629 R F +F + P + ++ I+ I H R S ++ ++LV L Q Sbjct: 2722 RQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKM 2781 Query: 2630 LPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQE 2689 LPT KFHYVFNLRDLS ++QG+L +T+EV+K P DL++LW HE +RV D+ D Sbjct: 2782 LPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVT 2841 Query: 2690 TLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGD----------------PK-YVP 2732 + ++ ++ F + ++ L I +F + D PK Y P Sbjct: 2842 WFDKALVSLVEEEFGE--EKKLLVDCGIDTYFVDFLRDAPEAAGETSEEADAETPKIYEP 2899 Query: 2733 VTDMAPLNKLLVDVLDSYNEV--NAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGG 2790 + + L + L L YNE A M++V F DA+ H+ +I+R++ +P+GNALLVGVGG Sbjct: 2900 IESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGG 2959 Query: 2791 SGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVA 2850 SGKQSL+RLA++I+G FQITL + Y +L DL Y A + F+ TD+++ Sbjct: 2960 SGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIK 3019 Query: 2851 EEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMN--DTRETCWKFFIEKVR 2908 +E FL +N++L+SGE+ LF DE++ I S + +K T E +F+ +VR Sbjct: 3020 DESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNENLHDYFMSRVR 3079 Query: 2909 RQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETE-GIPW 2967 + L ++LCFSPVG R RA KFPA+++ IDWF WP+DALV+VS FL + Sbjct: 3080 QNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSL 3139 Query: 2968 EVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAK 3027 E+K + M V E Y RR + TPK++L I+ Y+ + +K E+ Sbjct: 3140 EIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTL 3199 Query: 3028 IERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIA 3087 R+ GL KL+ + V L +L +E EL+ N+ AD +++ V ++A+ K KA Sbjct: 3200 ANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEV 3259 Query: 3088 DQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAV 3147 + + + + I ++++ + E L A+PAL A+ AL T+ +++ +++ G PP + Sbjct: 3260 QKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLI 3319 Query: 3148 VNVTAAVMIL---TAPGGKIPKDKS-----WKAAKIMMGKVDTFLDSLKKFDKEHIPEAC 3199 + + V++L KI +KS W+ + +M FL +L++F K+ I E Sbjct: 3320 MRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLM-TAGNFLQNLQQFPKDTINEEV 3378 Query: 3200 LKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELA 3259 ++ PY P ++ E + AGLCSW + F+ + +V P + L Sbjct: 3379 IEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHL 3438 Query: 3260 EAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLAS 3319 A + L + + ++ + A L + + +E+A EK ++A+ + A+ L+ GLA Sbjct: 3439 LAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAG 3498 Query: 3320 ENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPI 3379 E RW E + F +Q L GDVLL +AF+SY G F +++R+ L+ W + K I Sbjct: 3499 EKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLND-WRKEMKARK--I 3555 Query: 3380 PITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIK 3439 P L+ +L D ++ WN QGLP+D +S +N I+ R+PL++D Q QG WIK Sbjct: 3556 PFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIK 3615 Query: 3440 NKY-RSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKY- 3497 NK R+EL+ L K + + +E ++S G LLIE++GE +DP LD +L RN IK G Sbjct: 3616 NKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGSTF 3675 Query: 3498 -IKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKE 3556 +K+GDKEV+ FRL + TK NP Y PE+ A+ ++I+F VT GLEDQLL V+ E Sbjct: 3676 KVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTE 3735 Query: 3557 RPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEI 3616 + +LE+ + +L + K +KELED+LL RL++ G+ + D +L+ L TK TA E+ Sbjct: 3736 KQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEV 3795 Query: 3617 EEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAI 3676 +K+ + TEV+IN ARE YRP A R S+LYF++ ++ +N +YQ SL+ F +F+ ++ Sbjct: 3796 TQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSL 3855 Query: 3677 QRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVEL 3736 R+ + +R+ N+ + +TY VY Y ARGL+E K +F +T ++ + + E Sbjct: 3856 ARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEF 3915 Query: 3737 DFLLR----FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVES 3792 L++ KA P ++ W + LS++ +F ++ I + K WK + Sbjct: 3916 LTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWFDK 3975 Query: 3793 EAPEKEIFPKEW-KNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKS 3851 E PE+E P + K+ ++L ++R PDR + ++ + MG K+ EG ++ K+ Sbjct: 3976 ENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKT 4035 Query: 3852 YEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVA 3911 +EES P T + +LS G DP + ALGK+L + VS+GQGQEV A L Sbjct: 4036 WEESDPRTPLICLLSMGSDPTDSIIALGKRLKI-----ETRYVSMGQGQEVHARKLLQQT 4090 Query: 3912 AEKGHWVILQVRGGQHCRNIHLVARWLGTL-DKKLERYSTGSHEDYRVFISAEPAPSPET 3970 G W +LQ N HL ++ L D +E H+ +R++++ E Sbjct: 4091 MANGGWALLQ--------NCHLGLDFMDELMDIIIETELV--HDAFRLWMTTEAHKQ--- 4137 Query: 3971 HIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAV 4030 P +L+ +IK N+PP G+ A L + +QD L++ + ++K ML+A+ + H+ Sbjct: 4138 --FPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGS-QWKPMLYAVAFLHST 4194 Query: 4031 VAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLE---ANPKVPWDDLRYLFGEIMYGGH 4087 V ERRKFGA GWN Y FN D ++ + N+L+ V W +RY+ GEI YGG Sbjct: 4195 VQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGR 4254 Query: 4088 ITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLY 4147 +TDD+D+RL T+ + M D G+ IP Y +YI +SP ++ Sbjct: 4255 VTDDYDKRLLNTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVF 4314 Query: 4148 GLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLE 4207 GLHPNA+I + + ++ + T+L +QPK+T G +RE L Sbjct: 4315 GLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDE--TREAVVARLA------------ 4360 Query: 4208 LRRGGCPGTGFQVKAVLDDILEKIPET---FNMAEIMAKAAEKTPYVVVAFQECERMNIL 4264 DD+LEK+P F + E + K P + QE +RM + Sbjct: 4361 -----------------DDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRV 4403 Query: 4265 TNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLL 4324 + +R +L EL L + G + ++ ++ D +F +P W ++ S L W+ +L+ Sbjct: 4404 LSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWISST-LGFWFTELI 4462 Query: 4325 LRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNE-WPLDKMCLSVEVTKKN 4383 R + +W + P W+ GFFNPQ FLTA+ Q + R N+ W LD M L EVTK Sbjct: 4463 ERNSQFTSWVFN-GRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWM 4521 Query: 4384 REDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKN 4443 ++D++APP EG YVYGL++EGA WD + + E++ K L MPVI I A + + Sbjct: 4522 KDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIYA-ENNTLRDPR 4580 Query: 4444 IYECPVYKTRIRGP-TYVWTFNLKTKEKAAKWILAAVALLLQV 4485 Y CP+YK +R Y+ +L+T + W+L VALL V Sbjct: 4581 FYSCPIYKKPVRTDLNYIAAVDLRTAQTPEHWVLRGVALLCDV 4623 Score = 168 bits (426), Expect = 1e-40 Identities = 148/628 (23%), Positives = 282/628 (44%), Gaps = 50/628 (7%) Query: 190 LHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQLNRPK 249 L IE + W Q VL++++ Q L + P+ E E W RL + EQL P Sbjct: 250 LGKIEDCMKVWIKQTEQVLAENN-QLLKEADDVGPRAELEHWKKRLSKFNYLLEQLKSPD 308 Query: 250 VNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQADFTMLPT 309 V ++ +L AKS + + +T+ EA D V YL L + + +D + Sbjct: 309 VKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYSSDPLSMMD 368 Query: 310 FIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLS----------PEEVL 359 I +++ I I++ S YYNT +I + + NQII + +++ P++V+ Sbjct: 369 AIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYITNNGTASIWNQPQDVV 428 Query: 360 KGLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFK-DKEPVPWEFPSSLAFSRIN 418 + E++LS I +L Q Y C K K + ++F F + Sbjct: 429 E------EKILSAI--------KLKQEYQLCFHKTKQKLKQNPNAKQFDFSEMYIFGKFE 474 Query: 419 SFFQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDP 478 +F +R+ I +++ T + L+ + G L + T+ Y + +K +Y+ Sbjct: 475 TFHRRLAKIIDIFTTLKTYSVLQDSTIEG-----LEDMATK-YQGIVATIK---KKEYNF 525 Query: 479 LDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLIL 538 LD +FD+DY +F + DL L F + I+++ + L M + Sbjct: 526 LDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTF---AKIQNTNQALRMLKKFERLNIPN 582 Query: 539 AEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQER 598 + +Y ++LE + A++D LY Q P + +N PP+AG++ W+ +L R Sbjct: 583 LGIDDKYQLILENYGADIDMISKLYTKQKYD------PPLARNQPPIAGKILWARQLFHR 636 Query: 599 LEVSMKHLKHVEHP-VMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLG 657 ++ M+ + +HP V+S AEAK + Y+ M ++L ++ W+ + ++ H L Sbjct: 637 IQQPMQLFQ--QHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLRQI-EEIHVGLE 693 Query: 658 QPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNL 717 L+++ + + VNF ++ + RE + + Q E+ A SLF + + +++ N+ Sbjct: 694 ASLLVKAPGTGELFVNFDPQILILFRETECM-AQMGLEVSPLATSLFQKRDRYKRNFSNM 752 Query: 718 ELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHN 777 ++++ Y +K+ + A LI L +D L L W + Y++ + + Sbjct: 753 KMMLAEYQRVKSKIPAAIEQLIVPHLAKVDEALQPGLAALTWTSLNIEAYLENTFAKIKD 812 Query: 778 LQNRMQKAKQNIE-GISQAMKDWSANPL 804 L+ + + IE I +++ S+ PL Sbjct: 813 LELLLDRVNDLIEFRIDAILEEMSSTPL 840 >gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] Length = 4490 Score = 1896 bits (4911), Expect = 0.0 Identities = 1181/3618 (32%), Positives = 1906/3618 (52%), Gaps = 172/3618 (4%) Query: 946 AKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNF 1005 A+ N+ + ++ D+ ++ +SS V + K A E F++Y LWT++ +K F Sbjct: 966 ARKLKNFYPGVAEHKDISKLVLLLSSSVNSLRKAAHEALQDFQKYKTLWTEDRDVKVKEF 1025 Query: 1006 LIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCD 1065 L P+L + + +I Y +E+ + + V G L+ Sbjct: 1026 LANN--------------------PSLTEIRSEILHYATFEQEIDELKPIIVV-GALELH 1064 Query: 1066 CRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEV 1125 P K AL + W + R+L+ ++ + AF+ L++P++ D D + Sbjct: 1065 TEPMKLALSIEAKAWKMLLCRYLNEEYKKKMSYMIAFINEYLKKLSRPIR--DLDDVRFA 1122 Query: 1126 MGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQV 1185 M L +++ + D P+++ +L + E+ +E + L + + A+ V Sbjct: 1123 MEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSFNKLQSKAVSV 1182 Query: 1186 KLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKVFLLKGIM 1245 + + +Q S L + F F E + E P + P P ++ N++ + + Sbjct: 1183 QEDLVQVQPKFKSNLLESVEVFREDVINFAEAYELEGPMVPNIP-PQEASNRLQIFQASF 1241 Query: 1246 EAL-------SKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWK 1298 + L S LF +PV DY+ L +E+ LL++L+ + V +SI + W Sbjct: 1242 DDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWG 1301 Query: 1299 DINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERH 1358 D+++E+++ + +F R L K +K W AF+ L + + S + + N A+++RH Sbjct: 1302 DVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRH 1361 Query: 1359 WQQLMQATQVKFKM-SEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTW 1417 W ++ + T F + S+ L ++++ L ++D++ +I A+KE +E L + W Sbjct: 1362 WDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENW 1421 Query: 1418 SMMEFQHEPHPRTGTMMLKSSEV--LVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKL 1475 + G ++LK +E ++ +ED+ + L +L+ ++Y A F K + +W KL Sbjct: 1422 TNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKL 1481 Query: 1476 STADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPN 1535 ST+ +I W VQ W +LE++F+G DI QLP +++RF +I++ + +M+ A + PN Sbjct: 1482 STSSDIIEEWLVVQNLWVYLEAVFVGG-DIAKQLPQEAKRFQNIDKSWIKIMQRAHENPN 1540 Query: 1536 VVEA-TSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGND 1594 V+ + L L + L +C+K+L YLE KRL FPRF+FVS LL+IL +D Sbjct: 1541 VINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASD 1600 Query: 1595 PVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLN 1654 + HL + D++ ++ F D+ + V S+E E +V D G VE+WL Sbjct: 1601 SHTIQPHLPAVSDNINEVTFHAKDYDRIMAV----ISREGEKIVLDNSVMAKGPVEIWLL 1656 Query: 1655 RVLDRMCSTLRHEIPEAVVTYEEKPRE--QWILDYPAQIWWTTEVGLAFARLEEGYENAI 1712 +L S+L + I A + + ++ +PAQ+ L EE NA Sbjct: 1657 DLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGIQMLWTHDSEEALRNAK 1716 Query: 1713 KDY------NKKQISQLNVLITLLIGNLNAGDRMKIMTICTIDVHARDV---VAKMIVES 1763 D N+K + LN LI+ +L+ DR+K T+ TI VH RD+ + KM ++S Sbjct: 1717 DDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIHVHQRDIFDDLVKMHIKS 1776 Query: 1764 SQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSL 1823 F W Q R + E+ +I D Y E+LG T RLVITPLTDRCYITL Q+L Sbjct: 1777 PTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFLGCTDRLVITPLTDRCYITLAQAL 1836 Query: 1824 HLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGC 1883 + MGGAPAGPAGTGKTETTKD+GR LG V VFNCS+QMD++ G I+KGLAQ+G+WGC Sbjct: 1837 GMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGC 1896 Query: 1884 FDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFL-GEIIGLIPTVGIFITMNPGYAGR 1942 FDEFNRI + VLSV A Q+ V A + +KK F F G+ + L P GIF+TMNPGYAGR Sbjct: 1897 FDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGR 1956 Query: 1943 AELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDH 2002 ELPENLK FR AM+VPD ++I + L + GFLE +LA+KF LY LC+E L+KQ H Sbjct: 1957 QELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVH 2016 Query: 2003 YDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFP 2062 YD+GLR I SVL GS KR P +E ++MR LRD N+ K+V +D P+F+ LI DLFP Sbjct: 2017 YDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFP 2076 Query: 2063 ALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQ 2122 L + + + + L + LK+VQL E VRH + +G +GSGK+ Sbjct: 2077 GLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTT 2136 Query: 2123 VLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHD 2182 V+ L K R + ++PKA+T ++FG ++ T +W DG+FST+ R Sbjct: 2137 VITILMKAQTECGRPHREMRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKG 2196 Query: 2183 GPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATV 2242 ++ILDG +D +WIE+LN+V+DDNK LTLA+ +RIP+ + +L+FE+ ++ A+PATV Sbjct: 2197 ENIFLILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATV 2256 Query: 2243 SRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPV 2302 SR G++YI+ + L W P++ +W+++R Q E A + L++K ++ + Sbjct: 2257 SRMGMVYISSSALSWRPILQAWLKKRTAQ-EAAVFLTLYEKVFEDTYTYMKLNLNPKMQL 2315 Query: 2303 PEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFS 2362 E I L LLE L+ K S E FVF W+ G A+ + + + F Sbjct: 2316 LECNYIVQSLNLLEGLIPSKEEGGVSCVEHLHKLFVFGLMWSLG-ALLELESREKLEAFL 2374 Query: 2363 KWWINEFKTIKFP--SQGTIFDYYIDPDTKKFLPWTDKVPSFELDPD-VPLQAS-LVHTT 2418 + ++ + P S T++++Y+ D + W K+ + D +P +S LV Sbjct: 2375 RQHESKLDLPEIPKGSNQTMYEFYVT-DYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNV 2433 Query: 2419 ETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAM 2478 + IR + +D + ++ V+L G GT K+V++ L+ + + L +++ F+ T M Sbjct: 2434 DNIRTNFLIDTIAKQHKAVLLTGEQGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEPMM 2493 Query: 2479 LQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYD 2538 Q +E ++K+ G YGPPG +K+ FIDD+NMP ++++G + ++RQ M+ Y Sbjct: 2494 FQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYS 2553 Query: 2539 RHK----LTLKDIHNCQYVACM-NPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTI 2593 K T+ D+ Q +A M +P G I RL+R F VF + P ++ I+ I Sbjct: 2554 LDKPGDFTTIVDV---QLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGII 2610 Query: 2594 LTQHL-AFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGL 2652 + RS I + LV+ L Q LPT KFHY+FNLRDLS I+QG+ Sbjct: 2611 GCGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGM 2670 Query: 2653 LFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLF 2712 L AE + L+ L+ HE RV D+ + +D++ + + ++ + Sbjct: 2671 LTIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCIL 2730 Query: 2713 AKPNIFCHFAQGIGDPK---------YVP-VTDMAPLNKLLVDVLDSY----NEV--NAV 2756 +P F F + + +P VP + ++ P L + L Y NE+ Sbjct: 2731 PEP-YFVDFLREMPEPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTS 2789 Query: 2757 MNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKG 2816 ++LV F+DA+ H+ +I+RI+ + GNALLVGVGGSGKQSLSRLA++I+G +FQITL + Sbjct: 2790 LDLVFFKDAMTHLIKISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRS 2849 Query: 2817 YGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEV 2876 Y + +L DL A Y A F+ TDS++ +E FL +N+LL+SGEI LF DE+ Sbjct: 2850 YNVTNLTDDLKALYKVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEM 2909 Query: 2877 ENI----ISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFP 2932 + I IS M+ ++ T + +++FI + R+ L V+LCFSPVG R R+ KFP Sbjct: 2910 DEITQGLISVMKRELPR--HPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFP 2967 Query: 2933 AVVNCTAIDWFHEWPEDALVSVSARFLEETEGI-PWEVKASISFFMSYVHTTVNEMSRVY 2991 +++ +DWF WP +AL++V++ FL + + E+K + M H V+E Y Sbjct: 2968 GLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESY 3027 Query: 2992 LATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAK 3051 RR + TPK++L I Y+N+ A+K + + ER+ GL KL + V L Sbjct: 3028 FQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQD 3087 Query: 3052 LAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETD 3111 LA++E EL + AD+++ V + A+ +K K + + K + I + ++ E+ Sbjct: 3088 LAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESK 3147 Query: 3112 LAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMIL--------TAPGGK 3163 L A+PAL A+ AL+T+ N++ ++ PP ++ + V++L T K Sbjct: 3148 LEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEK 3207 Query: 3164 IPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTA 3223 SW + +M FL SL++F K+ I E ++ +PY + E + Sbjct: 3208 SCCKPSWGESLKLMSATG-FLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGN 3266 Query: 3224 AAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLT 3283 AGL SW + + FY + +V P + L + LA A +L + + + E A L + Sbjct: 3267 VAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQ 3326 Query: 3284 SAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVL 3343 + F+ A EK+ +AD + + A+ L+ GL+ E IRW + + F++Q L GD+L Sbjct: 3327 AKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDIL 3386 Query: 3344 LISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQ 3403 L + F+SY+G F + +RN L++ W + K IP T L+ +S+L D + W Q Sbjct: 3387 LCTGFLSYLGPFNQIFRNYLLKDQWEMELRARK--IPFTENLNLISMLVDPPTIGEWGLQ 3444 Query: 3404 GLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQ 3462 GLP D +S +N I+ R+PL++D Q QG WIK+K + ++L+ L K + +E Sbjct: 3445 GLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRTHLED 3504 Query: 3463 AISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKY--IKIGDKEVEYHPKFRLILHTKYF 3520 ++S G LLIE+I E +DP LD +L +N IK G +K+GDKE + F+L + TK Sbjct: 3505 SLSLGRPLLIEDIHEELDPALDNVLEKNFIKSGTTFKVKVGDKECDIMDTFKLYITTKLP 3564 Query: 3521 NPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKE 3580 NP + PE+ A+ ++I+F VT GLE+QLL V+ E+ +LE + L + K +KE Sbjct: 3565 NPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNKRKMKE 3624 Query: 3581 LEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPA 3640 LED+LL +LSA G+ + D +L+ L TTK TA+E+ EK+ A TE+KIN A+E +RPA Sbjct: 3625 LEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQEEFRPA 3684 Query: 3641 AERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSV 3700 A R S+LYF++ +++ +N +YQ SL F +F++++ R+ + ++R+ N+ + +TY V Sbjct: 3685 ATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEYLTYEV 3744 Query: 3701 YMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLR----FPFKAGVVSPVDFLQ 3756 + Y+ RGL+E K +F+ +T ++ + + E L++ KA P ++ Sbjct: 3745 FTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKPYRWIL 3804 Query: 3757 HQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKT-ALQKLCM 3815 W + LS++ +F + + I + K WK + +APE+EI P + + KL + Sbjct: 3805 DMTWLNLVELSKLPQFAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLL 3864 Query: 3816 VRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDV 3875 +R PDR + + ++ + + K+ E + K++EES T + LS G DP + Sbjct: 3865 IRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMGSDPTNQI 3924 Query: 3876 EALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVA 3935 +AL KKL + +S+GQGQEV A + ++ ++G WV+LQ N HL Sbjct: 3925 DALAKKLKL-----ECRTISMGQGQEVHARKLIQMSMQQGGWVLLQ--------NCHLGL 3971 Query: 3936 RWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHAN 3995 ++ L + L + S + +RV+I+ EP P +L+ ++K TNEPP G+ A Sbjct: 3972 EFMEELLETLIT-TEASDDSFRVWITTEPHDR-----FPITLLQTSLKFTNEPPQGVRAG 4025 Query: 3996 LHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTI 4055 L + QD L++ M +K ML+ + + H+ V ERRKFG GWN Y FN+ D + Sbjct: 4026 LKRTFAGINQDLLDISNLPM-WKPMLYTVAFLHSTVQERRKFGPLGWNIPYEFNSADFSA 4084 Query: 4056 SINVLYNYLEA---NPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEG 4112 S+ + N+L+ V W+ +RY+ GE+ YGG +TDD+D+RL + + +M E Sbjct: 4085 SVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEP 4144 Query: 4113 DVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEM 4172 G++IP Y EYI ++P ++GLHPNA+I + + T+ + T+ + Sbjct: 4145 SFCFYTGYKIPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITNI 4204 Query: 4173 QPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIP 4232 QPKE SG G G +RE L +D+L K+P Sbjct: 4205 QPKE--SGGGVGETREAIVYRLS-----------------------------EDMLSKLP 4233 Query: 4233 ETFNMAEI---MAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDV 4289 + E+ + K + QE +RM + + +R SL +L L ++G + ++ ++ Sbjct: 4234 PDYIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENL 4293 Query: 4290 EDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFF 4349 D ++ +P W ++ S L W+ +LL R + W + P W+ GFF Sbjct: 4294 RDALDNMYDARIPQLWKRVSWDSST-LGFWFTELLERNAQFSTWIFE-GRPNVFWMTGFF 4351 Query: 4350 NPQSFLTAIMQSMARKNE-WPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWD 4408 NPQ FLTA+ Q + R ++ W LD + + EV ++ +E++T+PP EG Y+YGL+M+GA WD Sbjct: 4352 NPQGFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWD 4411 Query: 4409 TQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVY-KTRIRGPTYVWTFNLKT 4467 + G + E+ K L +PV+ I AI + +Y CP+Y K R T++ L+T Sbjct: 4412 RRNGKLMESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDLTFITVVYLRT 4471 Query: 4468 KEKAAKWILAAVALLLQV 4485 WIL VALL + Sbjct: 4472 VLSPDHWILRGVALLCDI 4489 Score = 163 bits (412), Expect = 4e-39 Identities = 154/731 (21%), Positives = 308/731 (42%), Gaps = 46/731 (6%) Query: 69 PQSLKSKGVYFIKTKSE-NINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL------- 120 P LK ++F++ +++ IN + L+ + + L+ + ++L+++ Sbjct: 11 PDKLKGLCIFFVRCRNDVAINVKTIQEEALFTVLDASK--GLLNGIRDMLANIFLPAVLA 68 Query: 121 ------LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGT 174 LNQS+ + +E I + + L + G +K KT+ + Sbjct: 69 TNNWGALNQSKQGESEKHIFTETINRYLSFLDGARISIEGTVKLKTIDNVNF------SK 122 Query: 175 LESMERIPSSLDNL-LLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDA 233 L + E + ++ N +H +E ++ W QI VL +S Q + P E E W Sbjct: 123 LHTFEEVTAAASNSETVHQLEEVLMVWYKQIEQVLI-ESEQMRKEAGDSGPLTELEHWKR 181 Query: 234 RLLNLKCIHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLR 293 I EQ+ P ++ +L A S +++ +T+ E+ D V YL L Sbjct: 182 MSAKFNYIIEQIKGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLE 241 Query: 294 ILLEEMEQADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFL 353 + + + D + I +++ I I S YYNT R+ + + NQ++ + ++ Sbjct: 242 KVCQPLYNHDLVSMAHGIQNLINAIRMIHGVSRYYNTSERMTSLFIKVTNQMVTACKAYI 301 Query: 354 SPEEVLKGLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLA 413 + + E VL I + + KE ++ KL + +E Sbjct: 302 TDGGLNHVWDQETPVVLKKIQDCIFLFKEYQASFH---KTRKLISESSGEKSFEVSEMYI 358 Query: 414 FSRINSFFQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFAD 473 F + +F +R++ I E+ + L + G+ +++ IY V + Sbjct: 359 FGKFEAFCKRLEKITEMITVVQTYSTLSNSTIEGI--DIMAIKFRNIYQGVKKK------ 410 Query: 474 CKYDPLDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLME 533 +YD LDP + FD D+ DF KI L+ ++ F + + +LL L Sbjct: 411 -QYDILDPRRTEFDTDFLDFMTKINGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKL-N 468 Query: 534 RPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSL 593 P + E+ +L+ + AELD K LY +Q + P + +NMPP+AG++ W Sbjct: 469 IPCLGLEINHTIERILQYYVAELDATKKLYHSQK------DDPPLARNMPPIAGKILWVR 522 Query: 594 ELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCH 653 +L R+ + + ++S + K ++Y+++ +L + W+ + Q H Sbjct: 523 QLYRRISEPINYF-FKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIREISQ-LH 580 Query: 654 FNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKF 713 + L L +R + + VNF ++ V+RE K + + + ++P+ A+ L + Sbjct: 581 YALQATLFVRHPETGKLLVNFDPKILEVVRETKCM-IKMKLDVPEQAKRLLKLESKLKAD 639 Query: 714 VGNLELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVRE 773 L+ ++ +Y+E+ V +V L+ +++ ++ L T L W+ + + QEV Sbjct: 640 KLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEVEL 699 Query: 774 ILHNLQNRMQK 784 +L ++K Sbjct: 700 VLDMFNQLLKK 710 >gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] Length = 4116 Score = 1893 bits (4904), Expect = 0.0 Identities = 1171/3414 (34%), Positives = 1805/3414 (52%), Gaps = 213/3414 (6%) Query: 1200 LRRKCQQFELK---QHEFRERFRREAPFSFSDPNPY--------KSLNKVFLLKGIMEAL 1248 L ++C +FEL+ H E FR+ + + K+LN+ F E + Sbjct: 786 LIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNELSKNLNRAF---AEFELI 842 Query: 1249 SKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDID 1308 +K L E Y L+A + ++LW + E+W +N EQ+ + Sbjct: 843 NKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIAEE 902 Query: 1309 CKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRA----VSELQNPAIRERHWQQLMQ 1364 + L K + A L VK I + +S NP +++RHWQQ+ + Sbjct: 903 IGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQISE 962 Query: 1365 ATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQH 1424 + K +E T L+++L+ + +++ I A KE +EK L + W + F Sbjct: 963 IVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTFSF 1022 Query: 1425 EPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISI 1484 + T T +L + + + L+D+ ++ Q + S ++ E W++KL + Sbjct: 1023 VKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNLDA 1082 Query: 1485 WFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPG 1544 W + Q TW +LE IF SEDI Q+P + ++F ++ +K+LM AVK ++ A +P Sbjct: 1083 WLKCQATWLYLEPIF-SSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQPR 1141 Query: 1545 LYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSK 1604 + KL+ L +K L +YLE KRL FPRF+F+S+ +LL+ILS DP+ V HL K Sbjct: 1142 MAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLKK 1201 Query: 1605 LFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQE---CDLSGQVEVWLNRVLDRMC 1661 F+ + KL+F + L++ +GM S E E + F Q+ + G VE WL +V M Sbjct: 1202 CFEGIAKLEFTDN-----LEI-VGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMML 1255 Query: 1662 STLRHEIPEAVVTYEEKPREQWILDYPAQ-------IWWTTEVGLAFARLEEGYENAIKD 1714 +++R I + Y + PR W+L +P Q I+WT EV A A EN + D Sbjct: 1256 ASMREVIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQALA------ENTLLD 1309 Query: 1715 YNKKQISQLNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQA 1771 + KK Q+ ++ L+ G L++G R+ + + IDVHARDVVAK+ V F W + Sbjct: 1310 FLKKSNDQIAQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWIS 1369 Query: 1772 QLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAP 1831 QLR+ W + I + Y YEYLGN+PRLVITPLTDRCY TL +L L +GGAP Sbjct: 1370 QLRYYW--VAKDVQVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAP 1427 Query: 1832 AGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRIS 1891 GPAGTGKTETTKDL +AL VFNCS+ +DYK+ G +KGLAQ GAW CFDEFNRI Sbjct: 1428 EGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIE 1487 Query: 1892 VEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKA 1951 VEVLSV+A Q+ +Q AI K K F F G + L PT +FITMNPGYAGRAELP+NLKA Sbjct: 1488 VEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKA 1547 Query: 1952 LFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIK 2011 LFR AM+VPD+ LI EI L + GFL++R LA+K + Y LC E LS Q HYD+G+RA+K Sbjct: 1548 LFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVK 1607 Query: 2012 SVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRD 2071 SVL AG+LK P E +L+RAL D N+ K + D+P+F G+I DLFP + +P+ Sbjct: 1608 SVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDY 1667 Query: 2072 LNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTY 2131 F K++ +I ++KLQ F+ K++Q+ E++ VRH IVG+ GK+ K L Sbjct: 1668 EVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAAL 1727 Query: 2132 QNL----KRKPVAVD---LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGP 2184 +L + + AV+ ++PKA+T +L+G + V+ EW DG+ + R+ A+ D Sbjct: 1728 GDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDR 1787 Query: 2185 KWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSR 2244 KWII DG +D +WIE++NTV+DDNK L L S E I +N M L+FE + L A+PATVSR Sbjct: 1788 KWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSR 1847 Query: 2245 AGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFDKYL---PTCLDKLRFGFKKITP 2301 G++Y+ P LGW P+ S+++ K + ++ D ++ CL+ R K + Sbjct: 1848 CGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQ 1907 Query: 2302 VPEITVIQTILYLLECLLTEKTVPPDSPRELYE------------LYFVFTCFWAFGGAM 2349 I + +++ L LL E + EL E F+F+ W G + Sbjct: 1908 TSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTI 1967 Query: 2350 FQDQLVDYRVEFSKWWIN------EFKTIK------FPSQGTIFD-YYIDPDTKKFLPWT 2396 D + V F + K++K FP +G+I+D Y+I + + WT Sbjct: 1968 NADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQASGHWETWT 2027 Query: 2397 DKVPSFE--LDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDK 2454 + E + + ++ T ET R +F+ ++ P++ VG GTGKS + + Sbjct: 2028 QYITKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNF 2087 Query: 2455 LESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPE 2514 L L + YL + F+ T++ Q ++ L+++ +GPP KK V F+DD+NMP Sbjct: 2088 LLHLPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPA 2147 Query: 2515 VDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFT-IDSRLQRHF 2573 + YG P L+RQ +DH +W+D+ T DI + V M P G I R RH Sbjct: 2148 KEVYGAQPPIELLRQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHL 2207 Query: 2574 CVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTA 2633 + +++ + LT I+++I+ H + + R LV A +++ FLPT Sbjct: 2208 NIISINAFEDDILTKIFSSIVDWHFG-KGFDVMFLRYGKMLVQATKTIYRDAVENFLPTP 2266 Query: 2634 IKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHR 2693 K HYVFNLRD S + QG+L L+ +RLW+HE RV+ D+++D++D++ Sbjct: 2267 SKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFN 2326 Query: 2694 VTMASTKKFFDDLGDELLF------------AKPNIFCHFAQGIGDPK-YVPVTDMAPLN 2740 + +T F +++L + F + + D K Y +TD+ L Sbjct: 2327 MVKETTSNCFKQTIEKVLIHLSPTGKIVDDNIRSLFFGDYFKPESDQKIYDEITDLKQLT 2386 Query: 2741 KLLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRL 2799 ++ L+ +N ++ A M+LV+F A+ HI RI R+L+ +G+ LLVG+GGSG+QS ++L Sbjct: 2387 VVMEHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKL 2446 Query: 2800 AAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLIN 2859 + +++ +++QI + K Y D + DL ++ V +VFL D+Q+ +E F+ IN Sbjct: 2447 STFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDIN 2506 Query: 2860 DLLASGEIPGLFMEDEVENIISSMRPQVKSLG--MNDTRETCWKFFIEKVRRQLKVILCF 2917 LL +G++P +F DE +I+ M+ ++ G + T + + FFIE+V ++ L Sbjct: 2507 MLLNTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVINKISFSLAM 2566 Query: 2918 SPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFM 2977 SP+G R R R FP+++NC IDWF WP DAL V+ +FLE+ E + ++ + Sbjct: 2567 SPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVE-LDDNIRVEVVSMC 2625 Query: 2978 SYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMK 3037 Y +V ++S Y RR+NY TP ++LE I ++ LL KR E+ R GL K Sbjct: 2626 KYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQK 2685 Query: 3038 LQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVI 3097 L ASQV ++ +L + +L +E +++ + E + +K + +E + V Sbjct: 2686 LDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVA 2745 Query: 3098 NKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMIL 3157 + CE DLA+A PAL AA ALDTLN +++ +KS +PP V V ++ I+ Sbjct: 2746 AAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIM 2805 Query: 3158 ----------TAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKP-Y 3206 + GK+ +D W +K ++G + FL+SLK +DK++IP +K + + Sbjct: 2806 KGMKPERKPDPSGSGKMIED-YWGVSKKILGDL-KFLESLKTYDKDNIPPLTMKRIRERF 2863 Query: 3207 QGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCD----VAPKRQALEEANAELAEAQ 3262 +P F P I++ S+A GLC W VR EVY VAPKR+ L EA +LA Sbjct: 2864 INHPEFQPAVIKNVSSACEGLCKW----VRAMEVYDRVAKVVAPKRERLREAEGKLAAQM 2919 Query: 3263 EKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENI 3322 +KL++ + ++ + L L FE+ +K ++ + ++ ++ A +L+ GL E Sbjct: 2920 QKLNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKD 2979 Query: 3323 RWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPIT 3382 RW E+ + L GDVLL S V+Y+G FT YR + + W+ + +P Sbjct: 2980 RWTEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQ-WLAECKDKVIP---- 3034 Query: 3383 NGLDPLSL---LTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIK 3439 G SL L D + W GLP D S +N I+ N+ RW L++D Q KWIK Sbjct: 3035 -GFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIK 3093 Query: 3440 NKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKG--K 3496 N + ++L I+ +Y+ ++E A+ G +LIENIGE +D ++P+L + T K+ + Sbjct: 3094 NMEKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVE 3153 Query: 3497 YIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKE 3556 Y+++G+ +EY F+L + T+ NPHY PE+ + L+NF++T GL+DQLL V AKE Sbjct: 3154 YMRLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKE 3213 Query: 3557 RPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEI 3616 +P+LE+ K L + K LKE+ED +L LS + GN L D ++ L ++K + EI Sbjct: 3214 KPELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEI 3273 Query: 3617 EEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAI 3676 EK A +TE +I+E R Y+P A ++ ++F ++DL I P+YQ+SL F ++ ++ Sbjct: 3274 SEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSL 3333 Query: 3677 QRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVEL 3736 +T + E+ R+ + D T S+Y R LFE+DKL+F +T ++ KKE+ Sbjct: 3334 THSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVW 3393 Query: 3737 DFLLRFPFKAGVVSP---VDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESE 3793 FLL P +L + W I S + + L +E + WK + +S Sbjct: 3394 YFLLTGGIALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKLIYDSA 3453 Query: 3794 APEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYE 3853 P +E P WK L+K+ ++RCLRPD+M A++ F+ E MG ++E + + SY Sbjct: 3454 WPHEEQLPGSWKFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYN 3513 Query: 3854 ESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAE 3913 +SS + F+LSP DP+ + LG + + +SLGQGQ +A ++ A + Sbjct: 3514 DSSCCAPLIFVLSPSADPMAGLLKFADDLG--MGGTRTQTISLGQGQGPIAAKMINNAIK 3571 Query: 3914 KGHWVILQVRGGQHCRNIHLVARWLGTLDKKLER--YSTGSHEDYRVFISAEPAPSPETH 3971 G WV+LQ N HL A W+ TL+K E ++ +R+++++ P+ Sbjct: 3572 DGTWVVLQ--------NCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEK---- 3619 Query: 3972 IIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTL------EMCTKEMEFKCMLFALC 4025 P IL+N IK+TNEPP G+ ANL L + D + + C K + ++ MLF LC Sbjct: 3620 -FPVSILQNGIKMTNEPPKGLRANL---LRSYLNDPISDPVFFQSCAKAVMWQKMLFGLC 3675 Query: 4026 YFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYG 4085 +FHAVV ERR FG GWN Y FN DL IS+ + +L +VP+D L YL GE YG Sbjct: 3676 FFHAVVQERRNFGPLGWNIPYEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYG 3735 Query: 4086 GHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG--FQIPPNLDYKGYHEYIDENLP-PE 4142 G +TDD DRRL + L+ + E+ E LAPG + IPP+ Y+ Y +Y+ NLP Sbjct: 3736 GRVTDDKDRRLLLSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSYQSYIDYL-RNLPITA 3794 Query: 4143 SPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERK 4202 P ++GLH NA+I + +LF VL P+++ G+G S +E Sbjct: 3795 HPEVFGLHENADITKDNQETNQLFEGVLLTLPRQS---GGSGKSPQE------------- 3838 Query: 4203 GEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMA--KAAEKTPYVVVAFQECER 4260 V+ + DIL K+P F++ E+M + V QE R Sbjct: 3839 ----------------VVEELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIR 3882 Query: 4261 MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY 4320 N LT +RRSL L +KG++ +++++E++ ++ VP W A++YPS+ L + Sbjct: 3883 FNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYV 3942 Query: 4321 ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT 4380 ADLL R+ + W D P W++GF+ QSFLT + Q+ ARK P+D + EVT Sbjct: 3943 ADLLARLTFFQEW-IDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVT 4001 Query: 4381 KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME 4440 + M P +G+Y+ GLF+EGARWD +T I E+ K L +P+I++K Sbjct: 4002 PQETV-MENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFL 4060 Query: 4441 TKNIYECPVYKTRIRGPT---------YVWTFNLKTKEKAAKWILAAVALLLQV 4485 ++IY CPVYKT R T YV + L T WI VA L Q+ Sbjct: 4061 HQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLCQL 4114 >gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] Length = 4646 Score = 1344 bits (3478), Expect = 0.0 Identities = 950/3423 (27%), Positives = 1677/3423 (48%), Gaps = 299/3423 (8%) Query: 1263 KQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKE 1322 ++++ E++ LK +W + V I+ K W + ++ + ++S Sbjct: 1317 ERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPAR 1376 Query: 1323 MKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLADLL 1382 ++ + ++ + +K + V EL++ A+++RHW+QLM+ V + +SE TL + Sbjct: 1377 LRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSE-LTLGQIW 1435 Query: 1383 QLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLV 1442 ++L E V++++ A E +E+ LK + W+ E + + +++ + L Sbjct: 1436 DVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNY-QNKCRLIRGWDDLF 1494 Query: 1443 ETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGS 1502 ++++ + + +S Y F ++ SW+ KL+ ++ +W +VQR W +LE IF GS Sbjct: 1495 NKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGS 1554 Query: 1503 EDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKA 1562 DI+ LP ++QRF I+ EF ALM+ K+P V++ + G+ LE L L +KA Sbjct: 1555 ADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKA 1614 Query: 1563 LAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKP 1622 L EYLE +R +FPRFYFV DLL+I+ N + ++ +H K+F + + D S Sbjct: 1615 LGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNS--- 1671 Query: 1623 LKVGLGMYSKEDEYMVFDQECDLSGQVEV--WLNRVLDRMCSTLRHEIPEAV-------- 1672 V LG+ S+E E ++F ++ ++ WL V M TL + E+V Sbjct: 1672 --VVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGK 1729 Query: 1673 ---------VTYEEKPREQWILDYPAQIWWTTEVGLAFARLEEGYENAIKDYNKKQIS-Q 1722 +T+ +K + Q ++ AQI W+ V A + + G + A + Sbjct: 1730 ATSIDPNTYITWIDKYQAQLVV-LSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVT 1788 Query: 1723 LNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDE 1779 LNVL ++ R K+ + T VH RDV +I ++++++F W +Q+R +D Sbjct: 1789 LNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDP 1848 Query: 1780 EKRHCFANI----CDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPA 1835 ++ + +A+ Y +EYLG +LV TPLTDRCY+T+TQ+L +GG+P GPA Sbjct: 1849 KQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPA 1908 Query: 1836 GTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVL 1895 GTGKTE+ K LG LG V VFNC E D+++ G I+ GL Q GAWGCFDEFNR+ +L Sbjct: 1909 GTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERML 1968 Query: 1896 SVIAVQVKCVQDAIRAKKK----------AFNFLGEIIGLIPTVGIFITMNPGYAGRAEL 1945 S ++ QV+C+Q+A+R L + + + P + IFITMNPGYAGR+ L Sbjct: 1969 SAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNL 2028 Query: 1946 PENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDW 2005 P+NLK LFR AM PD +LI ++ML ++GF A +LA K + + LC E LS Q HYD+ Sbjct: 2029 PDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDF 2088 Query: 2006 GLRAIKSVLVVAGSLKRGDPSRA---------------------EDQVLMRALRDFNIPK 2044 GLRA+KSVLV AG++KR + E ++L++++ + +PK Sbjct: 2089 GLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPK 2148 Query: 2045 IVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDS------FVLKVV 2098 +V +D+P+ L+ D+FP + R + +K+ E+ L D +V KV+ Sbjct: 2149 LVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVL 2208 Query: 2099 QLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKR-KPVAVDLDPKAVTCDELFGII 2157 QL ++ Q+ H + +VG +GSGKS + L K + L+ + VA +DPKA++ D L+G + Sbjct: 2209 QLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTL 2268 Query: 2158 NPVTREWKDGLFSTIMRDLANITH---DGPKWIILDGDIDPMWIESLNTVMDDNKVLTLA 2214 +P TREW DGLF+ ++R + + +WI+ DGD+DP W+E+LN+V+DDNK+LTL Sbjct: 2269 DPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLP 2328 Query: 2215 SNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRK----- 2269 + ER+ L +R++FE+ L+ AT ATVSR G+++ + L + + ++++ R + Sbjct: 2329 NGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLD 2388 Query: 2270 --------------------------VQSEKANLMILF--DKYLPTCLDKLRFGFKKITP 2301 +Q + A +M + L T + F + I Sbjct: 2389 EGEDEAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMD 2448 Query: 2302 VPEITVIQTILYLLE--C--LLTEKTVPPDSPRELYEL------YFVFTCFWAFGGAMFQ 2351 + + + ++ +L C + PD P ++ +L Y V+ W+ G Sbjct: 2449 LTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSG---- 2504 Query: 2352 DQLVDYRVEFSKWWINEFKTIKFPSQGTI--FDYYIDPDTKKFLPWTDKVPSFELD---- 2405 D + R E ++ I T+ P+ I DY + + ++ PW KVP E++ Sbjct: 2505 DSRLKMRAELGEY-IRRITTVPLPTAPNIPIIDYEVSI-SGEWSPWQAKVPQIEVETHKV 2562 Query: 2406 --PDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNY 2463 PDV +V T +T+R + + + P++L G G+GK++ + L +L Sbjct: 2563 AAPDV-----VVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPD--- 2614 Query: 2464 LVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGT--------KKLVYFIDDMNMPEV 2515 ++ V NF +SA +L K + P G K LV F D++N+P++ Sbjct: 2615 -MEVVGLNF--SSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDM 2671 Query: 2516 DKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTS--GSFTIDSRLQRHF 2573 DKYGT + IRQ ++H +Y T + Q+V NP + G + R RH Sbjct: 2672 DKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHV 2731 Query: 2574 CVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTA 2633 V V +PG +LT IY T + A + +++ + L AA + + F Sbjct: 2732 PVVYVDYPGPASLTQIYGTF---NRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDT 2788 Query: 2634 IKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLD-LVRLWLHETERVYGDKMVDEKDQETLH 2692 + HY+++ R+++ +G+ + + P++ L+R+W HE R++ D++V+++++ Sbjct: 2789 -QPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTD 2847 Query: 2693 RVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNE 2752 K F ++ E ++P ++ ++ Y+PV D L + L + E Sbjct: 2848 ENIDTVALKHFPNIDREKAMSRPILYSNWLS----KDYIPV-DQEELRDYVKARLKVFYE 2902 Query: 2753 VNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQIT 2812 + LVLF + + H+ RI+RI P+G+ LL+GV G+GK +LSR A+++GL V+QI Sbjct: 2903 EELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIK 2962 Query: 2813 LKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFM 2872 + + Y D DL ++ KN F+M +S V + FL +N LLA+GE+PGLF Sbjct: 2963 VHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFE 3022 Query: 2873 EDEVENIISSMRPQVKSLG-MNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKF 2931 DE +++ + + G M D+ E +K+F +V R L V+ +P L+ RA Sbjct: 3023 GDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATS 3082 Query: 2932 PAVVNCTAIDWFHEWPEDALVSVSARF-----LEETEGI--------------PWEVKAS 2972 PA+ N ++WF +W +AL V F LE+ I P + + Sbjct: 3083 PALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREA 3142 Query: 2973 ISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLE 3032 I +VH T+++ + R TP+ +L+ I Y NL +KR+EL + L Sbjct: 3143 IVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLN 3202 Query: 3033 NGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEV 3092 GL K++ T QV++L+ L I+ EL+ KN +A+ ++ + + ++ K+K ++ + + Sbjct: 3203 VGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQE 3262 Query: 3093 KVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTA 3152 ++ + + +KQ + + DL K EPA++ AQ A+ ++ K +L E++S +PP AV Sbjct: 3263 QLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALE 3322 Query: 3153 AVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKP-YQGNPT 3211 ++ +L G+ D WK + ++ + + F+ ++ F E I +A + K Y NP+ Sbjct: 3323 SICLLL---GESTTD--WKQIRSIIMR-ENFIPTIVNFSAEEISDAIREKMKKNYMSNPS 3376 Query: 3212 FDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNK 3271 ++ E + S A + W I + + ++ V P R L++ + + Q+K + ++ Sbjct: 3377 YNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQM 3436 Query: 3272 IAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENF 3331 I +L A+++ + +E + + A + + L+ L++E RW ++ E F Sbjct: 3437 IRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETF 3496 Query: 3332 RSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLK-VPIPITNGLDPLSL 3390 ++Q T+ GD LL +AF++Y GYF ++ R L + + H+L+ I + Sbjct: 3497 KNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNL----FTTWSHHLQQANIQFRTDIARTEY 3552 Query: 3391 LTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIR 3450 L++ + W LP+D + TENA +L R+PLI+D Q ++I N+Y+ + Sbjct: 3553 LSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDR----K 3608 Query: 3451 LGQKSYLDV-----IEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGK--YIKIGDK 3503 + + S+LD +E A+ G+ LL++++ E+ DPVL+P+L R + G I +GD+ Sbjct: 3609 ITRTSFLDDAFRKNLESALRFGNPLLVQDV-ESYDPVLNPVLNREVRRTGGRVLITLGDQ 3667 Query: 3504 EVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQL 3563 +++ P F + L T+ + P++ ++ T +NF VTR L+ Q L V+ ERPD+++ Sbjct: 3668 DIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEK 3727 Query: 3564 KANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEA 3623 +++L K Q EF++ L++LE SLL L+ G L D ++ LE K A+E+ KV E Sbjct: 3728 RSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEET 3787 Query: 3624 KITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPAN 3683 I ++ + Y P + S +YF + L +I+ +YQ+SL+ F ++ + Sbjct: 3788 DIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLK 3847 Query: 3684 EV---KQRVINLTDEITYSVYMYTARGLFERDKLIF---LAQVTFQVLSMKKELNPVELD 3737 V QR+ +T ++ + ARG+ +D + F LA++ + ++ + E Sbjct: 3848 GVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKG-TVGEPTYDAEFQ 3906 Query: 3738 FLLR---FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEA 3794 LR AG + L + + LS + FK+L + ++ +++ ++S + Sbjct: 3907 HFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQAD-EQFGIWLDSSS 3965 Query: 3795 PEKEIFPKEWKNKT-------ALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVE 3847 PE+ + P W +T A+ +L +++ RPDR+ FV +G F+ Sbjct: 3966 PEQTV-PYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQP 4024 Query: 3848 FSKSY---EESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEV-V 3903 ++ E P+T + PG D VE L + N ++ ++++G + Sbjct: 4025 LDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAE-----QNTQITSIAIGSAEGFNQ 4079 Query: 3904 AENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAE 3963 A+ A++ A + G WV+L +N+HL WL L+KKL +S H +R+F++ E Sbjct: 4080 ADKAINTAVKSGRWVML--------KNVHLAPGWLMQLEKKL--HSLQPHACFRLFLTME 4129 Query: 3964 PAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFA 4023 P +P +L EPP G+ AN+ + + +C E + F Sbjct: 4130 INPK-----VPVNLLRAGRIFVFEPPPGVKANMLRTFS--SIPVSRICKSPNERARLYFL 4182 Query: 4024 LCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLE---------ANPKVPWDD 4074 L +FHA++ ER ++ GW++ Y F DL + + + +L+ + K+PW Sbjct: 4183 LAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSA 4242 Query: 4075 LRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLA------PGFQIPPNLDY 4128 L+ L + +YGG + +++D+RL T+L T + + LA Q+P + Sbjct: 4243 LKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRR 4302 Query: 4129 KGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSRE 4188 + + ++++ ++P GL NAE LT + +L+MQ E + Sbjct: 4303 EEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDED--------- 4353 Query: 4189 EKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKT 4248 L +E+K + G P + + L IP+T + + + K Sbjct: 4354 ----DLAYAETEKKTR-TDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENI-KD 4407 Query: 4249 PYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVAR 4308 P +E + L ++R+ L ++ +G+ T + L L +P +W Sbjct: 4408 PLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHY 4467 Query: 4309 AYPSMMGLAAWYADLLLRIRELEAWTTDFALPTT-------VWLAGFFNPQSFLTAIMQS 4361 P+ M + W +D RI++L+ + A V L G F P++++TA Q Sbjct: 4468 TVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQY 4527 Query: 4362 MARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKE 4421 +A+ N W L+++CL V VT + A V GL ++GA + ++ A Sbjct: 4528 VAQANSWSLEELCLEVNVTTSQGATLDAC---SFGVTGLKLQGATCNNNKLSLSNA---- 4580 Query: 4422 LTPAMPVIFIKAIPVDRMETK-NIYECPVYKTRIRGP-TYVWTFNLKTKEKAAKWILAAV 4479 ++ A+P+ ++ + E K ++ PVY R + F + TKE + V Sbjct: 4581 ISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGV 4640 Query: 4480 ALL 4482 A+L Sbjct: 4641 AVL 4643 Score = 47.4 bits (111), Expect = 3e-04 Identities = 116/640 (18%), Positives = 252/640 (39%), Gaps = 73/640 (11%) Query: 186 DNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQL 245 D L+ +++ + W +I+ V D A L E FW L I E+ Sbjct: 238 DPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQ-----EISFWLNLERALYRIQEKR 292 Query: 246 NRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLK--PLRILLEEMEQAD 303 P+V ++IL+ K + + T + + L+ ND +K PL LL E Sbjct: 293 ESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATE--- 349 Query: 304 FTMLPTFIAKVLDTICFIWATSEYYNTPARII-VILQEFCNQIIEMTRTFLSPEEVLKGL 362 + + + + I T R++ I ++ +Q++++ L +++ Sbjct: 350 LDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKV----LGTRKLMHVA 405 Query: 363 QGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFFQ 422 E E+V+ E++QT+D +++ +D E + + RIN + Sbjct: 406 YEEFEKVMVACF-------EVFQTWDDEYEKLQVLLRDIVKRKREENLKMVW-RINPAHR 457 Query: 423 RIQT-IEELYKTAIEFLKLEKIELGGVRGNLL-------GSLVTRIYDEVFELVKVFADC 474 ++Q ++++ K + +L + + +R + G + +V E++ AD Sbjct: 458 KLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADA 517 Query: 475 --------------KYDPLDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKS 520 + D LD + A + + +DR I + D K+ Sbjct: 518 NAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKN 577 Query: 521 SAKLLYMCG---GLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPL 577 + ++ + L RP I + + +++ ++++ + Q S+ + Sbjct: 578 ANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSH 637 Query: 578 IHKNMPPVAGQLKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLR--C 635 + +++PPV+G + W+ ++ +L ++K VE + G E + QK + + R Sbjct: 638 V-RDLPPVSGSIIWAKQIDRQLTA---YMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKL 693 Query: 636 HREKIYQQWVAGVDQDCHFNLG--------QPLILRDAASNL--IHVNFSKALVAVLREV 685 + ++I+ W V Q NLG + +R N+ + VNF ++ + +EV Sbjct: 694 NTQEIFDDWARKVQQR---NLGVSGRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKEV 750 Query: 686 ---KYLNFQQQKEIPDSAESLFSENETFRKFVGNLELIVGWYNEIKTIVKAVEFLLIKSE 742 K+L F+ I + A N+ + + +E + + + + + L+ + Sbjct: 751 RNLKWLGFRVPLAIVNKAH---QANQLYPFAISLIESVRTYERTCEKVEERNTISLLVAG 807 Query: 743 LEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQNRM 782 L+ L++ L W + Y+Q + E + N Q ++ Sbjct: 808 LKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKV 847 >gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens] Length = 798 Score = 1213 bits (3139), Expect = 0.0 Identities = 575/835 (68%), Positives = 689/835 (82%), Gaps = 37/835 (4%) Query: 3651 LNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFE 3710 +NDL+KI+P+YQFSLKAF++VF+KA++R P +++RV NL D IT+SVY YT RGLFE Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60 Query: 3711 RDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMD 3770 DKL +LAQ+TFQ+L M +E+N VELDFLLR P + G SPV+FL HQ WG +K LS M+ Sbjct: 61 CDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVEFLSHQAWGAVKVLSSME 120 Query: 3771 EFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKN 3830 EF NLD DIEGSAK WKK VESE PEKE P+EWKNKTALQ+LCM+R +RPDRMTYA+++ Sbjct: 121 EFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTALQRLCMLRAMRPDRMTYALRD 180 Query: 3831 FVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGK 3890 FVEEK+GSK+V GR+++F+ S+EES P+T +FFILSPGVDPLKDVE+ G+KLG+T +N Sbjct: 181 FVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQN 240 Query: 3891 LHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYST 3950 HNVSLGQGQEVVAE ALD+AA+KGHWVILQ NIHLVA+WL TL+KKLE +S Sbjct: 241 FHNVSLGQGQEVVAEAALDLAAKKGHWVILQ--------NIHLVAKWLSTLEKKLEEHSE 292 Query: 3951 GSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEM 4010 SH ++RVF+SAEPAPSPE HIIPQGILEN+IKITNEPPTGMHANLHKALD FTQDTLEM Sbjct: 293 NSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEM 352 Query: 4011 CTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKV 4070 C++E EFK +LFALCYFHAVVAERRKFG QGWNRSYPFN GDLTIS+NVLYN+LEAN KV Sbjct: 353 CSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKV 412 Query: 4071 PWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKG 4130 P+DDLRYLFGEIMYGGHITDDWDRRLCRTYL E+IR EMLEG++ LAPGF +P N+DY G Sbjct: 413 PYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPGFPLPGNMDYNG 472 Query: 4131 YHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEK 4190 YH+YID LPPESPYLYGLHPNAEIGFLT TSEKLFRTVLE+QP+++ + G G +REEK Sbjct: 473 YHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEK 532 Query: 4191 AGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPY 4250 VKA+L++ILE++ + FN+ E+MAK E+TPY Sbjct: 533 -----------------------------VKALLEEILERVTDEFNIPELMAKVEERTPY 563 Query: 4251 VVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAY 4310 +VVAFQEC RMNILT E++RSL+EL LGLKGELT+T+ +E+L AL++D VP++W RAY Sbjct: 564 IVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAY 623 Query: 4311 PSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPL 4370 PS GLAAW+ DLL RI+ELEAWT DF +P+TVWL GFFNPQSFLTAIMQS ARKNEWPL Sbjct: 624 PSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPL 683 Query: 4371 DKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIF 4430 D+M L ++TKKNRE+ +PPREG+Y++GLFMEGA WDTQ G+I EA+LK+LTP MPV+F Sbjct: 684 DQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMF 743 Query: 4431 IKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV 4485 IKAIP D+ + +++Y CPVYKT RGPTYVWTFNLKTKE +KW+LA VALLLQ+ Sbjct: 744 IKAIPADKQDCRSVYSCPVYKTSQRGPTYVWTFNLKTKENPSKWVLAGVALLLQI 798 >gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] Length = 4314 Score = 1160 bits (3001), Expect = 0.0 Identities = 949/3556 (26%), Positives = 1647/3556 (46%), Gaps = 284/3556 (7%) Query: 1062 LQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDG 1121 L +C P K + I++ + L + L +++ F+ A LT + + Sbjct: 908 LNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLT--IMPQSVEE 965 Query: 1122 LVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKL 1181 + + K++ER+ +F+ + LL+T E I + + + Sbjct: 966 IGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFELMMESH 1025 Query: 1182 AIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAP----FSFSDPNPYKSLNK 1237 + +K + ++ N S L+ Q+ E +F+ R+ + P N K Sbjct: 1026 QLMIKDQIEVMKGNVKSRLQIYYQELE----KFKARWDQLKPGDDVIETGQHNTLDKSAK 1081 Query: 1238 VFLLKGI--------MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSI 1289 + K I + L F + P++ + +++ ++W Sbjct: 1082 LIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGF 1141 Query: 1290 -----EDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLR 1344 EDW T + K E+ ++ + +R +++ + K VI L+ Sbjct: 1142 QEMANEDWITFRTKTYLFEEFLMN---WHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILK 1198 Query: 1345 AVSELQNPAIRERHWQQLMQATQVKFKMSEETTL-ADLLQL--NLHSYEDEVRNIVDKAV 1401 V + + HW L + + S E L DLL++ + + +++++ +A Sbjct: 1199 YV---RGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQ 1255 Query: 1402 KESGMEKVLKALD-----STWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLM 1456 E + + L+ LD + +++++++ + RT ++K + +V + DN+ LQ+L Sbjct: 1256 GEVTIREALRELDLWGVGAVFTLIDYE-DSQSRT-MKLIKDWKDIVNQVGDNRCLLQSLK 1313 Query: 1457 MSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRF 1516 S Y F +V+ W++KL+ D + +QR W +LE IF R LP + RF Sbjct: 1314 DSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFG-----RGALPKEQTRF 1368 Query: 1517 DDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPR 1576 + ++++F+++M D K V T+ G+ N L + L C+K+L E+LE KR AFPR Sbjct: 1369 NRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPR 1428 Query: 1577 FYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEY 1636 FYF+ DLL+IL +P + HL KLF + + F D+ K M S E E Sbjct: 1429 FYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCF-----DEKSKHITAMKSLEGEV 1483 Query: 1637 MVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYPAQIWWTTE 1696 + F + LS VE WLN + M TL + E V T +P+QI E Sbjct: 1484 VPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAE 1543 Query: 1697 VGLAFARLEEGYENAIKDYNKKQISQLNVLITLLI------------GNLNAGD-RMKIM 1743 + E ENAIKD++ QI L+ L GN +G +K+ Sbjct: 1544 Q----IKFTEDVENAIKDHSLHQIE--TQLVNKLEQYTNIDTSSEDPGNTESGILELKLK 1597 Query: 1744 TICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYL 1800 + +H DVV ++ V +++ + W+ QLR + + C + D++ QY+YEY Sbjct: 1598 ALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRF-YMKSDHTCCVQMVDSEFQYTYEYQ 1656 Query: 1801 GNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCS 1860 GN +LV TPLTD+CY+TLTQ++ + +GG P GPAGTGKTE+ K LG LG V VFNC Sbjct: 1657 GNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCD 1716 Query: 1861 EQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLG 1920 E +D KS G I+ GL + GAWGCFDEFNR+ VLS +++Q++ +QDA++ + LG Sbjct: 1717 EGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLG 1776 Query: 1921 EIIGLIPTVGIFITMNP---GYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFL 1977 + + + GIFITMNP GY GR +LP+NLK LFRP AM PD ELI E++L +EGF Sbjct: 1777 KEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFK 1836 Query: 1978 EARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSL-----KRGDPSRA-EDQ 2031 +A++L+RK + ++ L +ELL+ Q HYDWGLRA+K+VL +G+L K G A E Sbjct: 1837 DAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANESH 1896 Query: 2032 VLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAED 2091 ++++ALR + K D F LI D+FP +++ +KQ E + Sbjct: 1897 IVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIP 1956 Query: 2092 SFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCD 2151 + + K ++L E L R V IVG +G+GKS + + L + ++PKA+ Sbjct: 1957 NQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKVVKQYTMNPKAMPRY 2016 Query: 2152 ELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVL 2211 +L G I+ TREW DG+ + R + D WII DGDIDP WIESLN+V+DDN++L Sbjct: 2017 QLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLL 2076 Query: 2212 TLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQ 2271 T+ S ERI + VFE L A+PAT+SR G+++++ + N ++ SW+ R + Sbjct: 2077 TMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWL-RNQPA 2135 Query: 2272 SEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRE 2331 + NL Y L++ K+ V E +++ T++ L L R+ Sbjct: 2136 EYRNNLENWIGDYFEKA---LQWVLKQNDYVVETSLVGTVMNGLSHL--------HGCRD 2184 Query: 2332 LYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKK 2391 E F+ GG + +++ E W P D Y D + Sbjct: 2185 HDE--FIINLIRGLGGNLNMKSRLEFTKEVFHWARESPPDFHKP-----MDTYYDSTRGR 2237 Query: 2392 FLPWTDKVPSFELDPDVP--LQASLVHTTETIR-IRYFMD-LLMEKSWPVMLVGNAGTGK 2447 + K P D L ++ T + R + YF L + P +LVG G GK Sbjct: 2238 LATYVLKKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLSSDTKQPFILVGPEGCGK 2297 Query: 2448 SVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKP---LEKKSGRNYGPPGTKKLV 2504 +L+ L + + V + TTS L L + + +GR Y P ++LV Sbjct: 2298 GMLLRYAFSQLRSTQ--IATVHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLV 2355 Query: 2505 YFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTS--GS 2562 ++ D+N+P++DK+GT ++Q + ++ +YD + L + N Q VA M+ G Sbjct: 2356 LYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDEN-LEWVGLENIQIVASMSAGGRLGR 2414 Query: 2563 FTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQ---LVAAAL 2619 + +R + ++ +P +E L TIY L L + +I SS+ L + + Sbjct: 2415 HKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSSSKIYLLAGSMV 2474 Query: 2620 ALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAE--VLKTPLDLV-RLWLHETER 2676 +++++ A F HY F L+ GL E PLD V + +E R Sbjct: 2475 QVYEQVRAKFTVDDYS-HYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARR 2533 Query: 2677 VYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFC------HFAQGIGDPKY 2730 ++ DK+V K+ LH + T F D G ++L + F H + P Sbjct: 2534 LFRDKIVGAKE---LHLFDIILTSVFQGDWGSDILDNMSDSFYVTWGARHNSGARAAPGQ 2590 Query: 2731 VPVTDMAPLNKL----LVDVLDS----YNEVNAVMNLVLFEDAVAHICRINRILESPRGN 2782 PL KL L DV+ Y N ++++LF + + ++ RI+R+L P G+ Sbjct: 2591 PLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQNLDILLFHEVLEYMSRIDRVLSFPGGS 2650 Query: 2783 ALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVF 2842 LL G G G+++++ L +++ G +F + +GY + K DL A ++ V Sbjct: 2651 LLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVL 2710 Query: 2843 LMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKF 2902 L+ D Q FL +IN LL+SGE+PGL+ +E+E ++ ++ Q G + + Sbjct: 2711 LLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFG---PVFNY 2767 Query: 2903 FIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEET 2962 F ++++ L ++L S + PA+ + W W ++ + ET Sbjct: 2768 FTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSET 2827 Query: 2963 EG---------IPWEVKASI--SFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIK 3011 G + K S+ F S++ ++E + Y AT RY TFL Sbjct: 2828 GGGEKYNDKKRKEEKKKNSVDPDFLKSFL--LIHESCKAYGATPSRY-----MTFLH--- 2877 Query: 3012 LYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQ 3071 +Y + + K+ EL+ + L+ G+ KL + VD+L K Q LK K + AD +Q Sbjct: 2878 VYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQ 2937 Query: 3072 VVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNK 3131 ++ + + S++K ++ + ++ + E++ + +L + +P + A+ A+ + Sbjct: 2938 MITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKP 2997 Query: 3132 NNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFD 3191 +L+E++S PPD + ++ V+ L D SW + K + K + + FD Sbjct: 2998 ESLSEIRSLRMPPDVIRDILEGVLRLMG-----IFDTSWVSMKSFLAKRGV-REDIATFD 3051 Query: 3192 KEHIPEACLKAFKP--YQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQ 3249 +I + ++ + ++ +FDP+ + STAAA L +W +++ V + P Sbjct: 3052 ARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLET 3111 Query: 3250 ALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILL 3309 + L + +++ +++ + + +S L F+ T+E K + E I Sbjct: 3112 EQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKA 3171 Query: 3310 ANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWI 3369 A L+ L E+ RW V + TL L +AF++Y+ + R +E+ W Sbjct: 3172 AEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEE-WT 3230 Query: 3370 PYIHNLKVPIPITNGLDPLSL---LTDDADVATWNNQGLPSDRMSTENATI---LGNTER 3423 + GL+ L L +++ W ++GLPSD +S ENA + + + Sbjct: 3231 K-----------SAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQIIGLKS 3279 Query: 3424 W----PLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGET 3478 W P ++D Q +W+K + S L+ I +++ +E A+ G TL+I+ + + Sbjct: 3280 WSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTLIIQEM-DG 3338 Query: 3479 VDPVLDPLLGRNTIKKGK--YIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLIN 3536 V+PVL PLL R+ + +G ++IGDK ++Y+ +FRL L T+ NP P+ + T +N Sbjct: 3339 VEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVN 3398 Query: 3537 FLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNF 3596 F TR GL QLLA + E+PDLE+ K L + + + KI L +LE+SLL L+ + GN Sbjct: 3399 FTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNI 3458 Query: 3597 LGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNK 3656 L + L+E+L TK +++ I+E + E+ ++ +++ R+ Y P AE AS +YFI++DL+K Sbjct: 3459 LENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSK 3518 Query: 3657 INPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIF 3716 IN +Y+FSL AF +F++A+Q + +QR+ +L + + VY Y R LF+ D+L+F Sbjct: 3519 INNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMF 3578 Query: 3717 LAQVT-------FQVLSMKKELNPVELDFLLRFPFKAGVVS--PVDFLQHQGWG-GIKAL 3766 FQ V D L + + + P Q + W + Sbjct: 3579 ALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKI 3638 Query: 3767 SEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTAL-QKLCMVRCLRPDRMT 3825 + ++ L + A W+ + E+E FP K +L Q++ +V+ LRPDR+ Sbjct: 3639 ALPSLYQTLCFE---DAALWRTYYNNSMCEQE-FPSILAKKVSLFQQILVVQALRPDRLQ 3694 Query: 3826 YAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFT 3885 A+ F + +G K V + + Y+E+ I I+SPG DP ++++ L Sbjct: 3695 SAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQELANA---E 3751 Query: 3886 IDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKL 3945 H V++GQGQ +A L A G W+ L +N+HLV WL L+K+L Sbjct: 3752 RSGECYHQVAMGQGQADLAIQMLKECARNGDWLCL--------KNLHLVVSWLPVLEKEL 3803 Query: 3946 ERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQ 4005 + + +R++++AE P+ +L++++KIT E P G+ NL + + +T Sbjct: 3804 N--TLQPKDTFRLWLTAEVHPN-----FTPILLQSSLKITYESPPGLKKNLMRTYESWTP 3856 Query: 4006 DTLEMCTKEMEFKC-MLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYL 4064 + ++ K+ + LF+L +FHA ERR + QGW + Y F+ DL N++ Sbjct: 3857 E--QISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLF 3914 Query: 4065 EANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLE------GDVLLAP 4118 + V W+ + L +YGG I + +D R+ ++YL ++ + +++ + Sbjct: 3915 DGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPY 3974 Query: 4119 GFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETD 4178 +P + Y I++ + P +GL N + +S+++ + + Q + Sbjct: 3975 SVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPAN-----IARSSQRMISSQVISQLRILG 4029 Query: 4179 SGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMA 4238 G + + S +L P + ++ +K+ + N+ Sbjct: 4030 RSITAGSKFDREIWSNELSP-------------------------VLNLWKKLNQNSNLI 4064 Query: 4239 -EIMAKAAEKTPYVVVAFQECERMNI--LTNEMRRSLKELNLGLKGELTITTDVEDLSTA 4295 + + ++ +++F E+ N L + +SL L+ ++G ++++V+ L++A Sbjct: 4065 HQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASA 4124 Query: 4296 LFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWT----TDFALPTTVWLAGFFNP 4351 L P W ++ + + L+ R ++ W L T+ L+ F+P Sbjct: 4125 LLNQKCPLAWQSK-WEGPEDPLQYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHP 4183 Query: 4352 QSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQT 4411 +FL A+ Q AR +D + + +E + + GL +EG +D Sbjct: 4184 DTFLNALRQETARAVGRSVDSLKFVASWKGRLQE-----AKLQIKISGLLLEGCSFDGNQ 4238 Query: 4412 GVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYEC---PVYKTRIRGPTYVWTFNLKTK 4468 + ++ +P F+ IP D + EC PVY T V ++ Sbjct: 4239 LSENQLDSPSVSSVLP-CFMGWIPQDACGPYSPDECISLPVY-TSAERDRVVTNIDVPCG 4296 Query: 4469 EKAAKWILAAVALLLQ 4484 +WI AL L+ Sbjct: 4297 GNQDQWIQCGAALFLK 4312 Score = 40.8 bits (94), Expect = 0.031 Identities = 51/273 (18%), Positives = 119/273 (43%), Gaps = 24/273 (8%) Query: 531 LMERPLILAEVA-PRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQL 589 L++RP I E+ R +++ L D+ D + + + PL KN+ V + Sbjct: 427 LVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSGKNLSEVVNSI 486 Query: 590 KWSLELQERLEVSMKHLKHVEHPVMSGAEA-KLTYQKYDEMMELLRCHREKIYQQWVAGV 648 W +L+ +++ ++K + ++S + +Q ++++ L+ + ++ + W + Sbjct: 487 VWVRQLELKVDDTIK----IAEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSRDI 542 Query: 649 DQDCH-------FNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAE 701 ++ D+ L+ V++S LV +LREV+ L+ IP + Sbjct: 543 QSGLSDSRSGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLS-ALGFVIPAKIQ 601 Query: 702 SLFSENETFRKFVGNLELIVGWYNEI-KTIVKAVEFLLIKSELEAIDVKLLS-----AET 755 + + + F K L+ + +YN I + ++++ ++++S L + S ++ Sbjct: 602 QVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKS 661 Query: 756 TLFWNG----EGVFQYIQEVREILHNLQNRMQK 784 + W+ EG Q +Q E L +++K Sbjct: 662 QITWDNPKELEGYIQKLQNAAERLATENRKLRK 694 >gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] Length = 3092 Score = 954 bits (2467), Expect = 0.0 Identities = 655/2072 (31%), Positives = 1037/2072 (50%), Gaps = 210/2072 (10%) Query: 892 DESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMN 951 D+ P+F+I + D+D + F PT + D L+L+E + + NV + L+ Sbjct: 319 DQQRLPIFKIELTFDDDKMEFYPTFQDLEDN-VLSLVERIAEALQNVQTIPSWLSGTSTP 377 Query: 952 YKMDLEDNTDLIEMREEVSSLVINAMKEA--EEYQDSFERYSYLWTDNLQEFMKNFLIYG 1009 +D E ++ + ++ E + Y+ E+Y N+L+ G Sbjct: 378 VNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKY-------------NWLLDG 424 Query: 1010 CAVTAEDLDTW-TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP 1068 AV E+++T+ T+D T ++ E I+ + L E+ + + ++ DC Sbjct: 425 TAV--ENIETFQTEDH------TFDEYTEFIEKFLSLASEIMLLPQW-IHYTMVRLDCED 475 Query: 1069 FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGH 1128 K L + + + +N + N +A + +KE H Sbjct: 476 LKTGLTNKAKAF--------ANILLNDIASKYRKENECICSEFEAIKE-----------H 516 Query: 1129 LMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWAN--------TKK 1180 +KV E T+ M + L +E +T G E E+ L++QE + + Sbjct: 517 ALKVPE---TTEEMMD-LISYVEKARTVGIE---ELILRIQESKRQMSYFLDVFLFPQED 569 Query: 1181 LAIQVKLTVAPLQANEV----------------SILRRKCQQFELKQHEFRERFRREAPF 1224 LA+ + + P + N + + L K ++ L+ + R F Sbjct: 570 LALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKESRRMEEFTEF 629 Query: 1225 SFSDPNPYKSLNKVFLLKGIMEA------LSKSGGLFEVPVPDYKQLKACHREVRLLKEL 1278 + + + L K I E+ ++K LF+ + Y +L + ++ Sbjct: 630 AELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKF 689 Query: 1279 WDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKN 1338 ++ V+ S + W + D+N E M+ D ++F+ R + K +K + + + K Sbjct: 690 FNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFS---REIFKTLKFFQTKLKKELQEKR 746 Query: 1339 VITSLRAVSELQ-------NPAI-----RERHWQQLMQATQVKFKMSEETTLADLLQLNL 1386 R++ E + N I R RHW+Q+ + TTL +L+LNL Sbjct: 747 KAARKRSLEEEKIEEEPKDNATITMCRMRARHWKQISEIVGYDLTPDSGTTLRKVLKLNL 806 Query: 1387 HSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLE 1446 Y ++ I A KE +EK + + TW + F + TG +L S + + L+ Sbjct: 807 TPYLEQFEVISAGASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSSVDEIQAILD 866 Query: 1447 DNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIR 1506 D ++ Q + S ++ F E+ +W+ +L I W +VQ W +LE IF SEDI Sbjct: 867 DQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFC-SEDIM 925 Query: 1507 TQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEY 1566 Q+P + ++F +++ ++ +M+ K P V+ ATS GL KL+ + L K L Y Sbjct: 926 QQMPEEGRQFQTVDRHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAY 985 Query: 1567 LETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVG 1626 LE KRL FPRF+F+S+ ++L+ILS DP+ V HL K F+ + KL+F + K Sbjct: 986 LEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFLPNLDIK----- 1040 Query: 1627 LGMYSKEDEYMVFDQECDLS---GQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQW 1683 MYS E E + S G VE WL +V D M ++ I A + Y E R W Sbjct: 1041 -AMYSSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARRDW 1099 Query: 1684 ILDYPAQI-------WWTTEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNA 1736 + ++P Q+ +WT+E + EG +K Y K+ +QLN ++ L+ G L+ Sbjct: 1100 VREWPGQVVLCISQMFWTSETQEVISGGTEG----LKKYYKELQNQLNEIVELVRGKLSK 1155 Query: 1737 GDRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEEKRHCFANICDAQI 1793 R + + TIDVHARDVV MI V F W AQLR+ W+ E I + + Sbjct: 1156 QTRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENENAR--VRIINCNV 1213 Query: 1794 QYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTM 1853 +Y+YEYLGN+PRLVITPLTDRCY TL + +L +GGAP GPAGTGKTETTKDL +AL Sbjct: 1214 KYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQ 1273 Query: 1854 VYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKK 1913 VFNCS+ +DY + G +KGLA +GAW CFDEFNRI +EVLSV+A Q+ C+Q AI+ K Sbjct: 1274 CVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKL 1333 Query: 1914 KAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMA 1973 F F G + L P + ITMNPGYAGR+ELP+NLK LFR AM+VP++ LI EI L + Sbjct: 1334 VVFVFEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYS 1393 Query: 1974 EGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVL 2033 GFL AR L+ K + Y LC E LS Q HYD+G+RA+K+VLV AG+LK P+ ED +L Sbjct: 1394 YGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILL 1453 Query: 2034 MRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSF 2093 +R+++D N PK ++ D+P+F G+ DLFP + +P F + ++ LQ F Sbjct: 1454 LRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFF 1513 Query: 2094 VLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL-------KRKPVAVDLDPK 2146 + K++Q E++ VRH +VG + K++VL L T + + K + ++PK Sbjct: 1514 LEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPK 1573 Query: 2147 AVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMD 2206 ++T +LFG +PV+ EW DG+ + R+ A KW++ DG ID +WIES+NTV+D Sbjct: 1574 SITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLD 1633 Query: 2207 DNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIE 2266 DNK L L S E I ++ M L+FE L A+PATVSR G++Y+ P+ LGW P+VSSW+ Sbjct: 1634 DNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLN 1693 Query: 2267 RRK----VQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTE- 2321 K +A L LF +P L++ R ++ + T++ IL +L Sbjct: 1694 SLKGPLCEPEYQALLRGLFAWLIPPSLNQ-RVELFQLNYL-YTTIVSKILKILITFRISN 1751 Query: 2322 --KTVPPDSPRELYELY------FVFTCFWAFGGAMFQD--QLVDYRVEF---------- 2361 K VP + + + F+F+ W+ GG+ D ++ D + Sbjct: 1752 YFKYVPLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENP 1811 Query: 2362 -----SKWWINEFKTIKFPSQGTIFDYYIDPDTK-KFLPWTDKVPSFEL-DPDVPLQASL 2414 KW F +G ++DY + K +++ W + + + L D + +Q + Sbjct: 1812 VPDSVGKW------ECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKIQDII 1865 Query: 2415 VHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKL-ESLNTDNYLVQAVPFNFY 2473 V T +TIR + MDL + + P++ VG GTGKSV + DKL L D Y + + Sbjct: 1866 VPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSAR 1925 Query: 2474 TTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDH 2533 T++ +Q ++ L+K+ +GPP KK + FIDDMNMP ++KYG P L+RQ D Sbjct: 1926 TSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDC 1985 Query: 2534 RHWY---DRHKLTLKDIHNCQYVACMNPTSGSFT-IDSRLQRHFCVFAVSFPGQEALTTI 2589 HWY D K+TL DI + +A M P G + R RHF + +++ E + I Sbjct: 1986 GHWYDLKDTSKITLVDI---ELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRI 2042 Query: 2590 YNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIF 2649 +++I+ +L I +Q+V + ++++ LPT K HY FNLRD S + Sbjct: 2043 FSSIVAFYLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVI 2102 Query: 2650 QGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDE 2709 +G L + + ++RL++HE RV+ D+++++ D+ L ++T K F + Sbjct: 2103 RGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKE---- 2158 Query: 2710 LLFAKPNIFCHFAQGIG-----------------------DPKYVPVTDMAPLNKLLVDV 2746 + +IF H + D Y+ + ++ + ++ Sbjct: 2159 ---SFHSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQC 2215 Query: 2747 LDSYNEVNAV-MNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISG 2805 LD YN+ + MNLV+F + H+ RI R+L+ GNALLVG+GGSG+QSL+RLA ++ Sbjct: 2216 LDEYNQTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAK 2275 Query: 2806 LDVFQITLKKGYGIPDLKIDLAAQYIKAAVKN 2837 + +FQ + K YG+ + + D+ + +I V N Sbjct: 2276 MHIFQPEISKSYGMNEWREDMKS-FIAVPVTN 2306 Score = 427 bits (1097), Expect = e-118 Identities = 273/824 (33%), Positives = 424/824 (51%), Gaps = 72/824 (8%) Query: 3685 VKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLR--F 3742 +++R+ L D TY++Y R LFE+DKL+F + +L +KE+ EL FLL Sbjct: 2316 LEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLLTGGV 2375 Query: 3743 PFKAGVVSP-VDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFP 3801 K+ +P +LQ + W I SE F+ L W+++ +S+ P FP Sbjct: 2376 SLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPHNAKFP 2435 Query: 3802 KEW-KNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTS 3860 KN LQK+ ++RCLRPD++T AI N+V +K+G KFVE + +KSY +S+ + Sbjct: 2436 APMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSNCTIP 2495 Query: 3861 IFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVIL 3920 + F+LSPG DP+ + ++ K +SLGQGQ +A + A E+G WV L Sbjct: 2496 LIFVLSPGADPMASLLKFANDK--SMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWVCL 2553 Query: 3921 QVRGGQHCRNIHLVARWLGTLDKKLERYSTGS-HEDYRVFISAEPAPSPETHIIPQGILE 3979 Q N HL W+ L+K E +++ + + +R+++++ P+ P IL+ Sbjct: 2554 Q--------NCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSK-----FPVTILQ 2600 Query: 3980 NAIKITNEPPTGMHANLHKAL---DLFTQDTLEMCT-KEMEFKCMLFALCYFHAVVAERR 4035 N +K+TNEPPTG+ NL ++ + + + C KE+ ++ +LF +C+FHA+V ER+ Sbjct: 2601 NGVKMTNEPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERK 2660 Query: 4036 KFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRR 4095 KFG GWN Y FN DL ISI L ++ +P++ + YL GE YGG +TDDWDRR Sbjct: 2661 KFGPLGWNIPYGFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRR 2720 Query: 4096 LCRTYLAEYIRTEMLEG-DVLLAP--GFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPN 4152 L T LA++ ++E +P + PP Y+ Y E+I + + P ++GLH N Sbjct: 2721 LLLTMLADFYNLYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHEN 2780 Query: 4153 AEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGG 4212 +I ++ LF ++L Q +GA +GS + E Sbjct: 2781 VDISKDLQQTKTLFESLLLTQGGSKQTGA---------SGSTDQILLE------------ 2819 Query: 4213 CPGTGFQVKAVLDDILEKIPETFNMAEIMAK--AAEKTPYVVVAFQECERMNILTNEMRR 4270 + DIL K+P F++ + K + V QE ER N L +R Sbjct: 2820 ----------ITKDILNKLPSDFDIEMALRKYPVRYEESMNTVLVQEMERFNNLIITIRN 2869 Query: 4271 SLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIREL 4330 +L++L +KG + + + +E LS +L VP+ W R+YPS+ L ++ D L R+ L Sbjct: 2870 TLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFL 2929 Query: 4331 EAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAP 4390 + W P WL+GFF Q+FLT MQ+ ARK P+D + EV + D + Sbjct: 2930 QDWYNS-GKPCVFWLSGFFFTQAFLTGAMQNYARKYTTPIDLLGYEFEVIPSDTSDTS-- 2986 Query: 4391 PREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVY 4450 P +G Y++GL+++GARWD ++G++AE K L MP+I+IK R+ + Y CP+Y Sbjct: 2987 PEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLY 3046 Query: 4451 KTRIRGPT---------YVWTFNLKTKEKAAKWILAAVALLLQV 4485 KT R T +V LKT + WI VALL Q+ Sbjct: 3047 KTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLCQL 3090 >gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo sapiens] Length = 4515 Score = 701 bits (1810), Expect = 0.0 Identities = 506/1918 (26%), Positives = 886/1918 (46%), Gaps = 266/1918 (13%) Query: 2774 RILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKA 2833 R+L N +G+ G GK++ + LA Y++ ++++ + + K +I A Sbjct: 2653 RLLSRELENCFQIGIDGCGKKTCATLACYLTDNKLYRVPISHKCAYIEFKEVFKKVFIHA 2712 Query: 2834 AVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMN 2893 +K P+V ++ + + ++ FL +N +++SG IP LF E+++I +R + G Sbjct: 2713 GLKGKPTVLMVPNLNIEQDSFLEDLNYIISSGRIPDLFENVELDSIAMKIRYLTEQSGHM 2772 Query: 2894 DTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVS 2953 D R++ FF +++ + L + + SP G R R +P++++ IDW+ WPE+AL+ Sbjct: 2773 DNRQSLLSFFQKRIYKNLHIFVIMSPEGPSFRQNCRVYPSMISSCTIDWYERWPEEALLI 2832 Query: 2954 VSARFLEETEGIP--WEVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIK 3011 V+ FL+E +K ++ +H ++ +++R Y R+ YTTP ++L+ ++ Sbjct: 2833 VANSFLKEKVNFENRENLKEKLAPTCVQIHKSMKDLNRKYFEETGRFYYTTPNSYLQFME 2892 Query: 3012 LYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQ 3071 + ++L + E+ K +R GL + + V +++ +L I +++QK + + L++ Sbjct: 2893 TFAHILRAREEEMQTKRDRFHMGLSTILEATTLVTEMQEELLILGPQVEQKTKETETLME 2952 Query: 3072 VVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNK 3131 + +++ V K + + Q+E V + V + + +L PA A AL+ L+K Sbjct: 2953 KLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQKTANELKSVLPAFDKAIVALNALDK 3012 Query: 3132 NNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFD 3191 ++ EL+ + PP V+ V AV IL + K +W AK+++ + FL L D Sbjct: 3013 ADVAELRVYTRPPFLVLTVMNAVCIL------LQKKPNWATAKLLLSETG-FLKKLINLD 3065 Query: 3192 KEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQAL 3251 K+ IP+ K P F+P I S A LC W I + ++EV V PK+ + Sbjct: 3066 KDSIPDKVFVKLKKIVTLPDFNPHKISLVSVACCSLCQWVIALNNYHEVQKVVGPKQIQV 3125 Query: 3252 EEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLAN 3311 EA L A+++L+ + + + +L L +A++ AEK +R A+ Sbjct: 3126 AEAQNVLKIARQRLAEKQRGLQLVEEHLLFLQAAYKDTVAEKQLLANRKTMASRRFQCAS 3185 Query: 3312 RLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPY 3371 L+ L E RW E++ ++ + GD+LL +A + Y G T ++R ++ K+ Sbjct: 3186 VLLTVLEDEKTRWQETINQIDNKLEGILGDILLSAACIVYSGILTPEFRQLIVNKWETFC 3245 Query: 3372 IHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQ 3431 I N I +++ + ++ +++ W+NQGLP + S ENA ++ N ++WPL++D Sbjct: 3246 IEN---GISLSSKFSLIKVMAQKYEISRWHNQGLPHGQYSVENAILIKNGQQWPLLIDPH 3302 Query: 3432 LQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNT 3491 Q KWI+ S L+ + + +Y IE A+ G ++L++N+ ET+ P L +L ++ Sbjct: 3303 RQAHKWIRQMEGSRLQKLSIEDSNYTKKIENAMKTGGSVLLQNLLETLAPGLKAILKKDI 3362 Query: 3492 I-KKGKY-IKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLL 3549 KKG Y I++GD E EY+ FRL L T+ NPH+ P + T+INF VT GL+DQLL Sbjct: 3363 YQKKGHYFIRVGDAEFEYNSNFRLYLSTEIDNPHFLPSVYNFVTMINFTVTFQGLQDQLL 3422 Query: 3550 AAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETT 3609 + VV E P LE ++ L +S + I L+ELE+ L L A G+ L D +V+ L + Sbjct: 3423 STVVTHEVPHLEDQRSKLLESISLDAITLEELEEKTLNLLQKALGSILDDDKIVDTLRKS 3482 Query: 3610 KHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFN 3669 K T++EI +++ K E +I R+NY P A R +LLYF++ DL +IN +YQFSL F+ Sbjct: 3483 KMTSNEISKRIEATKKAESEIQAIRKNYLPIATRGALLYFLVADLTQINYMYQFSLDWFH 3542 Query: 3670 VVFEKAI-------------QRTTP------------------ANEVKQRVINLTDEITY 3698 VF ++ ++ +P N + + + + D +T Sbjct: 3543 QVFVSSVVSKSKEQEHSFKREKVSPKEVHEFISISKEPNLENEKNLLDKHIKSAIDMLTK 3602 Query: 3699 SVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELD--FL----------------- 3739 S++ + LF DKL F ++ ++ N ++ D FL Sbjct: 3603 SIFKVVSSALFNEDKLCFSFRLCTVIMQNNANGNLIQDDIGFLPEEEWNIFLYSGILINI 3662 Query: 3740 --------LRFPFKAGVVSPVDFLQHQGWGGIKALS-EMDEFKNLDSDIEGSAKRWKKLV 3790 L F+ G + +L W + +S ++ F L + + +W Sbjct: 3663 KSALSQSRLTSTFEIGESQHLQWLSDSRWRQCQYVSTHLEPFSLLCKSLLSNVSQWDTFK 3722 Query: 3791 ESEAP---------------EKEIFPKE------------------WKNKTALQKLCMVR 3817 S+A E+ P E W+ T+ Q+L +V+ Sbjct: 3723 NSKAVYSLISTPFSSENASLEENTKPPEETELLNENKETCNPINFPWEKLTSFQRLILVK 3782 Query: 3818 CLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEA 3877 LRP+ + +++ F+ EKMG+K+++ V +Y+ S+ T + I + G+D + Sbjct: 3783 VLRPESLNNSVRKFITEKMGNKYLQRTGVNLKDAYKGSNARTPLILIQTHGIDLTNILLR 3842 Query: 3878 LGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEK-GHWVILQVRGGQHCRNIHLVAR 3936 ++L T + + +SLG+ Q AE+ + A K WV LQ N HL Sbjct: 3843 FAQELKGTTHHVTI--ISLGRDQAAKAEDLILKALTKTQQWVFLQ--------NCHLATS 3892 Query: 3937 WLGTLDKKLERYSTGS---HEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMH 3993 ++ L +E +++ + ++R+++S++ S P +L+ +KI E P G+ Sbjct: 3893 FMPRLCTIVESFNSPNVTIDPEFRLWLSSKSYSS-----FPIPVLKKGLKIAVESPQGLK 3947 Query: 3994 ANLHKALDL-----FTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPF 4048 +NL + T++ E +K +LF+LC+F+AV+ ER+ +G GWN +Y F Sbjct: 3948 SNLLQTFGCTGSGEVTEEIFENPDCGQWWKKLLFSLCFFNAVINERKNYGILGWNIAYKF 4007 Query: 4049 NNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTE 4108 N+ DL ++I VL N L P + W LRYL GE++YGG + D+WD+R +T L ++ E Sbjct: 4008 NSSDLGVAIKVLENSLRGQPSISWQALRYLIGEVIYGGRVIDNWDKRCLKTLLYKFCNPE 4067 Query: 4109 MLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRT 4168 +L+ D F + K Y I + P + G+HP A EK Sbjct: 4068 VLKDD------FSFSRSASIKDYIHIIQSLPDDDLPEVLGIHPEAIRSCWETQGEKFIEN 4121 Query: 4169 VLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDIL 4228 ++ MQPK T +L + P + K E V +L D+L Sbjct: 4122 LIAMQPKTT-------------TANLMIRPEQSKDE--------------LVMEILSDLL 4154 Query: 4229 EKIPETFNMAEIMA--------------------KAAEKTPY---VVVAF--QECERMNI 4263 +++P T EI + P V++ F QE +R + Sbjct: 4155 KRLPLTVEKEEIAVGTPSTLKSMMSSSIWESLSKNLKDHDPLIHCVLLTFLKQEIKRFDK 4214 Query: 4264 LTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADL 4323 L + +SLK+L L +KGE+ +T ++E++ + VP W AY S L++W DL Sbjct: 4215 LLFVIHKSLKDLQLAIKGEIILTQELEEIFNSFLNMRVPTLWQKHAYRSCKPLSSWIDDL 4274 Query: 4324 LLRIRELEAWT------------------------------------TDF--ALPTTVWL 4345 + R+ W +F P+ WL Sbjct: 4275 IQRLNFFNTWAKVAYTAIQRRYMRFVTVWKQSIPSTSQKCKHPEDSENNFFEGFPSRYWL 4334 Query: 4346 AGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEV----TKKNREDMTAPPRE-------- 4393 FF PQ+FL A++Q R +D + + V T K+ + P++ Sbjct: 4335 PAFFFPQAFLAAVLQDYGRSRGIAVDALTFTHHVISNTTDKDEKFSVFMPKKLNIVRRAF 4394 Query: 4394 --------GSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKN-- 4443 G Y++GLF+EGARW+ + ++ ++ E+ P I+ + +T N Sbjct: 4395 KGSASSHTGVYIFGLFIEGARWNREQKILEDSLPLEMCCDFPDIYFLPTKIS-TKTPNAS 4453 Query: 4444 --------IYECPVYKTRIRG--------PT-YVWTFNLKTKEKAAKWILAAVALLLQ 4484 +ECPVY+T R PT ++ + L TK+ + WI VALL + Sbjct: 4454 NQTDSELYAFECPVYQTPERSRILATTGLPTNFLTSVYLSTKKPPSHWITMRVALLCE 4511 Score = 620 bits (1600), Expect = e-177 Identities = 420/1383 (30%), Positives = 677/1383 (48%), Gaps = 219/1383 (15%) Query: 1271 EVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFV 1330 ++ L K+LW+ + +W+ + + I+VE + + K + L+K + D Sbjct: 995 DLTLRKKLWEAQEEWKRASWEWRNSSLQSIDVESVQRNVSKLMHIISVLEKGLPKSDMVT 1054 Query: 1331 GLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYE 1390 L V L + L NP ++ RHW+ L + + + + +LL L + YE Sbjct: 1055 HLKQVVTEFKQELPIIIALGNPCLKPRHWEALQEIIGKSVPLDKNCKVENLLALKMFQYE 1114 Query: 1391 DEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRT--GTMMLKSSEVLVETLEDN 1448 +E+ ++ A E+ +EK+L + W+ H ++ S + + LE++ Sbjct: 1115 NEINDMSTSATNEAALEKMLFKIIDFWNTTPLPLILHHTEIYSIFIIPSIDDISAQLEES 1174 Query: 1449 QVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQ 1508 QV L + S ++ V W Q L+ + W QR W +LE +F SE IR Q Sbjct: 1175 QVILATIKGSPHIGPIKDLVNEWDQNLTLFSYTLEEWMNCQRNWLYLEPVFHSSE-IRRQ 1233 Query: 1509 LPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLE 1568 LP +++ F + +K +M N ++ T+ G+ L+ L +K+L +YLE Sbjct: 1234 LPAETELFSQVISMWKKIMSKIQNKQNALQITTSAGVLEILQNCNIHLEHIKKSLEDYLE 1293 Query: 1569 TKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLK-FRLDASDKPLKVGL 1627 KRL FPRFYF+S+A+LLDIL++ +P V HL K F+++ +L ++ D +K+ Sbjct: 1294 VKRLIFPRFYFLSNAELLDILADSRNPESVQPHLVKCFENIKQLLIWKQDIGPPAVKM-- 1351 Query: 1628 GMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDY 1687 + S E E +V ++ + VE WL V M L+ +E+ IL + Sbjct: 1352 -LISAEGEGLVLPKKIRVRSAVEQWLVNVEKSMFDVLK----------KERYIYNIILLF 1400 Query: 1688 PAQIWWTTEVGLAFARLEEGYENAIKDYNKKQISQLN---------VLITLLIGNLNAGD 1738 +QI + + +F + Y+++++ +++ V +++ N+ Sbjct: 1401 QSQIMFYNDCVKSF----------VSSYSREKLEKVHAGLMCHLEEVADLVVLDTSNSRT 1450 Query: 1739 RMKIMTICTIDVHARDVVAKMIVES---SQAFTWQAQLRHRWDEEKRHCFANICDAQIQY 1795 + + + + VH RD+V +++++ ++ F W L+++W+E+++ C+ + +A Y Sbjct: 1451 KAILGALLILYVHCRDIVINLLLKNIFNAEDFEWTRHLQYKWNEKQKLCYVSQGNASFTY 1510 Query: 1796 SYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVY 1855 YEYLG T RLVITPLTDRC++TL ++LHL +GG PAGPAGTGKTET KDL ++LG Sbjct: 1511 GYEYLGCTSRLVITPLTDRCWLTLMEALHLNLGGCPAGPAGTGKTETVKDLAKSLGKHCV 1570 Query: 1856 VFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKA 1915 VFNC E +DYK + GL Q+GAW CFDEFN I +EVLSVIA Q+ ++ A Sbjct: 1571 VFNCFEDLDYKIVRKFFFGLVQSGAWSCFDEFNLIDLEVLSVIASQILTIKAAKDNYSAR 1630 Query: 1916 FNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEG 1975 F G+ I + + +FITMNP Y G ELP+NLK+LFRP AM+VP +++I EI+L + G Sbjct: 1631 FVLEGKEIRINMSCAVFITMNPRYGGGVELPDNLKSLFRPVAMMVPHYQMIAEIILFSFG 1690 Query: 1976 FLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQ---V 2032 F A L+ K LY L ++ LS+QDHY++GLR++K VL++AG+ KR +E + Sbjct: 1691 FKSANSLSGKLTNLYELARKQLSQQDHYNFGLRSLKIVLIMAGTKKREFKCLSEADETLI 1750 Query: 2033 LMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDS 2092 ++ A+R+ ++PK +D+P+F +IGD+FP + V + L EK+I + +L LQ S Sbjct: 1751 VIEAIREASLPKCPPEDVPLFENIIGDIFPEVTVLKVNQLALEKVIYTATQQLGLQNWSS 1810 Query: 2093 FVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL---------KRKPVA--- 2140 K++Q LQV V +VG G GK+ V + L K L +RK + Sbjct: 1811 QKEKIIQFYNQLQVCVGVMLVGPTGGGKTTVRRILEKALTLLPIADFLSVAERKSASKIS 1870 Query: 2141 -----VD---LDPKAVTCDELFGIINPVTREWKDGLFSTIMR------------------ 2174 VD L+PK VT EL+G ++P T EW DGL S +R Sbjct: 1871 ERKGKVDICVLNPKCVTLSELYGQLDPNTMEWTDGLLSATIRSYVYFNTPKNTKKDIDLR 1930 Query: 2175 ------DLANI----------THDGP------------------KWIILDGDIDPMWIES 2200 DL+N+ T D +WIILDG +D W+E+ Sbjct: 1931 LKSRISDLSNVFKLDSSDTTETDDNIFEEIEKVVKIPENHNFDWQWIILDGPVDTFWVEN 1990 Query: 2201 LNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPV 2260 LN+V+DD + L LA++ERI L +R++FE+ +L A+PATVSR ++Y++P DLGW P Sbjct: 1991 LNSVLDDTRTLCLANSERIALTNKIRVIFEVDNLSQASPATVSRCAMVYMDPVDLGWEPY 2050 Query: 2261 VSSWIERRKVQSEKANLMILFDKYLPTCLDKLRF--GFKKITPVP--EITVIQTILYLLE 2316 V SW+ + ++ + L + D L+F +K P P +ITV+ T+ +L+ Sbjct: 2051 VKSWLLKTSKIISQSGVDCLEFMIKNSVTDGLQFIRNRQKFQPYPMEDITVVITLCRILD 2110 Query: 2317 CL------------------------------LTEKTVP------------PDSPRELYE 2334 +T K + PD ++ + Sbjct: 2111 AFFDFMGKNGGFEQSDDLNDTSSKEANSQRESVTFKDIEKRDENTWYPEKNPDKLTKIIQ 2170 Query: 2335 LYFVFTCFWAFGGAMFQ----------------DQLVDYRVEFSK--------------- 2363 FVF WAFGGA+ + D L +F K Sbjct: 2171 KLFVFAFTWAFGGALNREDEHRENIPFCPSLEPDSLAKVTYDFDKLVHELFGNSSQVGWK 2230 Query: 2364 -WWINEFK-----TIKFPS-QGTIFDYYIDPDTKKFLPWTDKVPSFE--LDPDVPLQASL 2414 W ++ + I P+ + +IF Y++D + +F+PW+D VP+ + + L +L Sbjct: 2231 HWGQSQGRRRKGNCINLPTGECSIFGYFVDIEQCEFIPWSDLVPNDQTLIQRGTSLLTNL 2290 Query: 2415 -------------------VHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKL 2455 T +T + + M LL++ S PV+L G +G GK+ + L Sbjct: 2291 QRSGGNFLKITECGECINYTATRDTTCLSFLMSLLLKNSCPVLLTGESGVGKTAAINQML 2350 Query: 2456 ESL 2458 E L Sbjct: 2351 EKL 2353 Score = 134 bits (336), Expect = 3e-30 Identities = 74/240 (30%), Positives = 125/240 (52%), Gaps = 2/240 (0%) Query: 2464 LVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAP 2523 +V + F+ T+A + ++ K L +++ G P +++ FIDDMNMP D YG P Sbjct: 2426 VVSTINFSTNVTAAKTKEMILKKLIRRTKDTLGAPKNNRILIFIDDMNMPVSDMYGAQPP 2485 Query: 2524 HTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSFPGQ 2583 LIRQ +D YD K T K+I + VA P I RL +HF + + P Q Sbjct: 2486 LELIRQLLDLGGVYDTEKNTWKNIQDLSIVAACVPVVND--ISPRLLKHFSMLVLPHPSQ 2543 Query: 2584 EALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVFNLR 2643 + L TI+ L + + + + +Q+ Q+++ +LA++ ++ LPT K HY+FNLR Sbjct: 2544 DILCTIFQAHLGIYFSINNFTPEVQKSKDQIISCSLAIYHQVRQNMLPTPTKCHYMFNLR 2603 Query: 2644 DLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFF 2703 D+ + GLL + V+ + L++HE RV+ D+++D D+ +R+ + F Sbjct: 2604 DMFKLLLGLLQADRTVVNSKEMAALLFVHEATRVFHDRLIDFTDKSLFYRLLSRELENCF 2663 >gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] Length = 4753 Score = 158 bits (399), Expect = 1e-37 Identities = 229/1063 (21%), Positives = 417/1063 (39%), Gaps = 163/1063 (15%) Query: 1784 CFANICDAQIQYSYEYLGNTPRLVITP--LTDRCYITLTQSLHLIMGGAPAGPAGTGKTE 1841 C+ ++ Y+YEYLG PRL P L +R + L +L + G GP G GK Sbjct: 1638 CWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKRA 1695 Query: 1842 TTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQ 1901 L +ALG + + CS Q++ + N G Q GAW ++ +++ +LS + + Sbjct: 1696 IVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQR 1755 Query: 1902 V--------KCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGY-------AGRAELP 1946 + Q+A R +++G +++ GY A + +P Sbjct: 1756 LGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVLRALSSAVP 1815 Query: 1947 ENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLS-------- 1998 NL L RP A+ +PD + E+ L+ G +A +A + ++L +EL+S Sbjct: 1816 ANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLP 1875 Query: 1999 --KQDHYDWGLRAIKSVLVVAGSLKRGDP---SRAEDQVLMRALRDFNIPKIVTDDLPVF 2053 KQ D I+++ V K P + E+ L+R+ + + +L Sbjct: 1876 LLKQILED----TIRTLNVTKEEPKCQKPRSLAAIEEAALLRSPLFSILNGLHLHNL--- 1928 Query: 2054 MGLIGDLFPALDVPRKRDLNFEKIIKQSIVE----LKLQAEDSFVLKVVQLEELLQVRHS 2109 GL+ LFP+ + + K++K +VE + L + + QL + L Sbjct: 1929 RGLLCALFPSASQVLAEPMTY-KLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASG 1987 Query: 2110 VFIVGNAGSGKSQVLKSLNKTYQNLKR---------KPVAVD-LDPKAVTCDELFGIINP 2159 + ++G AGSGK+ SL K L +PV + L P ++ E G + Sbjct: 1988 ILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEFLGWLEG 2047 Query: 2160 VTREWKDGLFSTIMRDLANITHDGPK-----------WIILDGDIDPMWIESLNTVMDDN 2208 W G+F ++R + G K WII DG + W++S+ ++ + Sbjct: 2048 SC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSEL 2105 Query: 2209 KVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWI--- 2265 L+L S ++I L+ E++ +P V +++ + W ++S+ + Sbjct: 2106 PQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCG-GEQTWQCILSALMASL 2164 Query: 2266 --ERRKVQSEKANLMILFDKYLPTCLDKLRF-GFKKI----------TPVPEITVIQTIL 2312 E R A L + + +P L L G + V E+T + IL Sbjct: 2165 PYEYRLQHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVCAGVAEVTSMARIL 2224 Query: 2313 YLLECL---LTEKTVP---------------------------------PDSPRE--LYE 2334 + L L L E+ P PD RE L Sbjct: 2225 HSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSDDVPDKCREHLLAV 2284 Query: 2335 LYFVFTCFWAFGGAMFQD--QLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKF 2392 F+F W FG + + D + S ++ + + P +FD ++ P+ Sbjct: 2285 SSFLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYP--EPPPSALVFDLHVSPEDGTL 2342 Query: 2393 LPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMG 2452 +P+T + S + + + + +T R+ Y +DLL+ PV+L G A TGKS + Sbjct: 2343 VPFTGQYLSSHIKGTL---GTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFVE 2399 Query: 2453 DKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNM 2512 +E + Y F+ +L ++ + + L++ ++D+++ Sbjct: 2400 VLVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLEDLHL 2459 Query: 2513 PEVDKYGTVAP-HTLIRQHMDHRHWYDRHKLTLKDIH-NCQYVACMN-PTSGSFTIDSRL 2569 D + P +RQ MD Y L L+ + ++A + P + RL Sbjct: 2460 ATSDPEKSCQPVLETLRQAMDGT-VYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPRL 2518 Query: 2570 QRHFCVFAVSFPGQEALTTIYNTILTQHL-AFRSVSMAIQRISSQLVAAALALHQKITAT 2628 R F V A+ Q L + I+ L F SV + ++ LV A++ + + Sbjct: 2519 FRLFTVLALESMTQATLLERHVPIIQAWLERFPSVERE-RALARGLVRASVEAWEAVCNC 2577 Query: 2629 FLPTAIKFHYVFNLRDLSNIF----------------------------QGLLFSTAEVL 2660 F+P+ + HY F+L +S++ GL + V+ Sbjct: 2578 FMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVM 2637 Query: 2661 KTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFF 2703 ++VRLWLHE +R + D++ +++ ++ + + F Sbjct: 2638 MATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVF 2680 Score = 119 bits (298), Expect = 7e-26 Identities = 157/722 (21%), Positives = 292/722 (40%), Gaps = 77/722 (10%) Query: 2768 HICRINRILESPRGNALLV-GVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDL 2826 H+ R+ R+L PR + LL+ G G+G+ + LA+ I F + I D Sbjct: 2871 HVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCLRDA 2930 Query: 2827 AAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLA---SGEIPGLFMEDEVENIISSM 2883 + A + + P V L+ S V L ++ LLA SG PG + E +++ I + Sbjct: 2931 SWH---AGMLSQP-VALLVPSGVD----LTTLHRLLALATSGSFPGQYTEADLDRIGEHL 2982 Query: 2884 RPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCT--AID 2941 + + N +E + F ++V L + + ++ + F ++ +ID Sbjct: 2983 PRENLGVKQNIKKEMVLQRFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATASID 3042 Query: 2942 WFHEWPEDALVSVSARFLEETEGIPWEVKA-SISFFMSYVHTTVNEMSRVYLATERRYNY 3000 + W + AL V+ LE + +P + + + + + M+ ++L+ + + Sbjct: 3043 RYEPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSATHYHEH 3102 Query: 3001 -------TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLA 3053 TPKTFL+ + + L + ++ K +R++N L L+ + + Sbjct: 3103 LCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTHANLIF 3162 Query: 3054 IQEAELKQKNESADQLIQVVGIEAEKVSKEKAIAD--QEEVKVEVINKNVTEKQKACETD 3111 E +LK +S Q +E K+ ++ + + +E +E + + Q E Sbjct: 3163 DLEQQLKDSGKSLSMFQQQ--LEQSKLLYKQQLEECRHQENLIENLARQRDALQAQREAF 3220 Query: 3112 LAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWK 3171 L + A L E L L + E++S+ +PP++VV VT A+ L + W Sbjct: 3221 LEQMSKAFL---EPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDL------FHHETGWA 3271 Query: 3172 AAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWC 3231 +AK ++ D F L F KE I ++ L P D +R+ S AA L +W Sbjct: 3272 SAKQLLCTED-FYQELVFFPKEKITDSELIKLHLILKAPGMDDAALRAVSRPAASLAAWL 3330 Query: 3232 INIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATA 3291 ++ + +C P L++ A L Q +L + + E + L E A A Sbjct: 3331 WAVLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQETLEHNLALAKMVEDAQA 3390 Query: 3292 E-----KIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLIS 3346 K Q + ++ + A L + W ++ + + +T+ GD LL S Sbjct: 3391 SHNCVAKTLSQAQCGQYHKWPMKA-----ALLTPMRAWTTQLQKLKGRCMTVFGDTLLCS 3445 Query: 3347 AFVSYVGYFTKKYRNELMEKFWIPYIHNLK------------------VPIPITNGL--- 3385 A + Y+G F R EL+++ W+ + V IP N L Sbjct: 3446 AAIIYLGPFPPLRRQELLDE-WLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPLLAT 3504 Query: 3386 ----DPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTE-----RWPLIVDAQLQGIK 3436 LSLL+ +++ W+ P + + +L + RWPL++D + + Sbjct: 3505 HSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNEALI 3564 Query: 3437 WI 3438 W+ Sbjct: 3565 WL 3566 Score = 62.4 bits (150), Expect = 1e-08 Identities = 196/1003 (19%), Positives = 347/1003 (34%), Gaps = 145/1003 (14%) Query: 3544 LEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALV 3603 LE+Q+L ++ +E P+LE +L + ++ E+ LL L + + Sbjct: 3757 LEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFL 3816 Query: 3604 ENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQF 3663 N+ + ++ E + +++ YRP + L+ L + P++ Sbjct: 3817 RNIVRAQGKLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCM 3876 Query: 3664 SLKAFNVVFEKAIQRTTP---------ANEVKQRVINLTDEITYSVYMYTARGLFERDKL 3714 S + + V ++A+ P A+ + Q +LT ++ S TA GL + + Sbjct: 3877 SPENWLAVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTV--TALGLTQVPLV 3934 Query: 3715 IFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVS-----PVDFLQHQGWGGIKALSEM 3769 L + + K EL+ L +P A S PV + W G KA E Sbjct: 3935 GALGALALLQATGKAS----ELERLALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHEC 3990 Query: 3770 D------EFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTAL-QKLCMVRCLRPD 3822 + F L + + G + W+ + + P +L QKL + R LRP+ Sbjct: 3991 EMLELLPPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPE 4050 Query: 3823 RMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALG--K 3880 + A+ +F +G E + ++ S + + +L P P + L + Sbjct: 4051 CLAGALADFTTSLLGRPLDENTYAP-TMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQ 4109 Query: 3881 KLGFTIDNGKLHNVSLGQGQEV-----VAENALDVAAEKGHWVILQVRGGQHCRNIHLVA 3935 KL G+ + G E V + L A +GHW++L N HL+ Sbjct: 4110 KLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLD--------NCHLMP 4161 Query: 3936 RW-----------LG------------TLDKKLERYSTGSHEDYRVFISAEPAPSPETHI 3972 W LG LD+ R + H D+R+++ P+ + Sbjct: 4162 HWPKELLQLLLELLGRAKVVADLESEQLLDQPESRNVSTVHRDFRLWLI---VPAESSAS 4218 Query: 3973 IPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVA 4032 +P A+ + P + +L L L M+ L H ++ Sbjct: 4219 LP------AVLTQHSMPVFWNQSLELGHVLIDSVELAQQVLYMQPPTQALPLLLLHGLLL 4272 Query: 4033 ERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDW 4092 R+ +G + ++ LT + + L A+ P ++ L + YGG + D Sbjct: 4273 HRQLYGTRLQAHRGRWSQVTLT-QVLQTQDQLWASLSNPRAAMQELAASVFYGGPLGDTE 4331 Query: 4093 DRR----LCRTYLA----EYIRTEMLEGDVLLAPGFQIPP--NLDYKGYHEYIDENLP-P 4141 DR L + L+ +++ + LLA +P LD + LP P Sbjct: 4332 DREALISLTQACLSPSSGSWVQPHTPQS--LLATLMPLPELRELDAMAECKAQMHLLPSP 4389 Query: 4142 ESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSER 4201 P L GL + L S L + P +P R Sbjct: 4390 PEPRLCGLSEGPQAWLLRRQSRALLSALQRSSP--------------------VWVPESR 4429 Query: 4202 KGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAA-----EKTPYVVVAFQ 4256 +G L RR QV L+ + + + E A + + P V Sbjct: 4430 RGAQLAERR--LRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPLEGVLET 4487 Query: 4257 ECERMNILTNEMRRSLKELNLGLKGELTI-TTDVEDLSTALFYDTVPDTWVARAYPSMMG 4315 E ++ L ++R L L LKG + ++ AL+ +P W A Sbjct: 4488 EALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQP 4547 Query: 4316 LAAWY------ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAI-----MQSMAR 4364 W LL+R + A + L+ F +P+ L A+ + Sbjct: 4548 PWHWLRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALDQNVP 4607 Query: 4365 KNEWPLDKMCLSVEVTKKNREDMTAP-------------PREGSYVYGLFMEGARWDTQT 4411 + +P + +S ++ K E + P P G + GL + A WD Sbjct: 4608 SSNFPGSRGSVSSQLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAEWDPIA 4667 Query: 4412 GVIAEARLKELTPAMPVIFIKAIP----VDRMETKNIYECPVY 4450 G + ++ + +P PV P + +Y CPVY Sbjct: 4668 GALQDSPSSQPSPLPPVSISTQAPGTSDLPAPADLTVYSCPVY 4710 Score = 44.7 bits (104), Expect = 0.002 Identities = 70/406 (17%), Positives = 153/406 (37%), Gaps = 56/406 (13%) Query: 1256 EVPVPDYKQLKACH-REVRLLKELWDMVVVVNTSIEDWKTTKWKDINV----EQMDIDCK 1310 E PVP L C R + + +W + V++ +I +WK + + E+ + Sbjct: 1002 ETPVP----LPICGTRPIVQQQRIWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLT 1057 Query: 1311 KFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQV-K 1369 + A+ +L+ + + ++ + L + L ++ + Q L++A + Sbjct: 1058 EAARMSTTLELHSPVLQHCMRILGEFRSYLPLLTKLGSLHPQSL---NCQCLLRALGLGS 1114 Query: 1370 FKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQ------ 1423 + E TL LL L + D + + + ++ ++ L W + + Sbjct: 1115 LQTIELLTLGQLLTYPLLEFADRINQVWQNENERIHAQETIRRLQRYWEARQLRLLNFIL 1174 Query: 1424 HEPHPR----------------------TGTMMLKSSEVLVETLEDNQVQLQNLMMSKYL 1461 H P+ +GT +L L ++++++ L ++ + Sbjct: 1175 HVPYEPPASERSKRQVLRSPQWEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKS 1234 Query: 1462 AHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGD--SQRFDDI 1519 K W + +++ +W Q+ W L + +++ Q P + RF + Sbjct: 1235 GDLNKIALEWVAIMHGLGALLEVWLTFQQKWIFLNKVL---HEMKIQFPNADLNSRFKVM 1291 Query: 1520 NQEFKALMEDAVKTPNVV-----EATSKP-----GLYNKLEALKKSLAICEKALAEYLET 1569 + +++ LM +V P V+ A P L L+A L +L L Sbjct: 1292 DDQYRTLMRISVADPMVLSLVVPSAERSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYG 1351 Query: 1570 KRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFR 1615 FPR +F+S ++L+ +L+ + E + + F + + FR Sbjct: 1352 VCAHFPRLFFLSDSELVALLAARLESCEAQLWVRRCFPHVHAVSFR 1397 >gi|71061468 centromere protein E [Homo sapiens] Length = 2701 Score = 47.8 bits (112), Expect = 3e-04 Identities = 99/485 (20%), Positives = 189/485 (38%), Gaps = 86/485 (17%) Query: 3236 RFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE---LNANLSNLTSAFEKATAE 3292 R EV + K Q L+E +L QE++S ++ KI E L L N E E Sbjct: 1121 RLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETE 1180 Query: 3293 KIKCQQ-------EADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLI 3345 +++ Q E + + + L +E + + G+ ++ + Sbjct: 1181 RLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIA 1240 Query: 3346 SAFVSYVGYFTKKYRNELMEKFW-------IPYIHN-LKVPIPITNGLDPLSLLTDDADV 3397 + + R + EK + H L+ IP+ + + LL + +V Sbjct: 1241 HIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLH--EEQELLPNVKEV 1298 Query: 3398 A----TWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQ 3453 + T N L +++ +T+++T L E L ++ + Q + + E+K++ + Sbjct: 1299 SETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQ-------ESQEEIKSLTK-E 1350 Query: 3454 KSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRL 3513 + L I++A+ L E+I ET+ + + + K+ + + + +K+ E ++ Sbjct: 1351 RDNLKTIKEALEVKHDQLKEHIRETLAKIQE-----SQSKQEQSLNMKEKDNE---TTKI 1402 Query: 3514 ILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNE 3573 + + F P ++ + ++ D++ + VAKE+ DL++L+ L ++ Sbjct: 1403 VSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKS--VAKEKDDLQRLQEVLQSESDQ 1460 Query: 3574 FKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEA--KITEVKIN 3631 K +KE+ KH +E E KV K E IN Sbjct: 1461 LKENIKEI--------------------------VAKHLETEEELKVAHCCLKEQEETIN 1494 Query: 3632 EARENYRPAAERASLLYFILNDL-----NKINPVY----QFSLKAFNVVFEKAIQRTTPA 3682 E R N S + L + NKI +Y QF++K + V EK Sbjct: 1495 ELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEK-------V 1547 Query: 3683 NEVKQ 3687 NE+KQ Sbjct: 1548 NELKQ 1552 Score = 46.2 bits (108), Expect = 7e-04 Identities = 195/1049 (18%), Positives = 397/1049 (37%), Gaps = 186/1049 (17%) Query: 3017 LAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIE 3076 L++K TE+ ++LE KLQ+ ++ + + ++ +KQ +E +++ ++ + Sbjct: 1500 LSEKETEISTIQKQLEAINDKLQNKIQEIYEKE-----EQFNIKQISEVQEKVNELKQFK 1554 Query: 3077 AEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEAL----DTLNKN 3132 + +K+ A+ E +E+ N+ + E Q+ + + K + + QEAL D L +N Sbjct: 1555 EHRKAKDSALQSIESKMLELTNR-LQESQEEIQI-MIKEKEEMKRVQEALQIERDQLKEN 1612 Query: 3133 N---LTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKK 3189 + ++K + +TA + ++ K+ + ++T L + Sbjct: 1613 TKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQ 1672 Query: 3190 FDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQ 3249 E++ E + T + + +RS +R E K++ Sbjct: 1673 ILHENLEE---------MRSVTKERDDLRSVEETLKVERDQLKENLR--ETITRDLEKQE 1721 Query: 3250 ALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKAT----AEKIKCQQEADATNR 3305 L+ + L E QE + +++ ++E +SN+ E + A+ +K Q+E + Sbjct: 1722 ELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHM 1781 Query: 3306 VILLANRLVG---GLASE---------------NIRWAESVENFRS---QGVTLCGDVLL 3344 + + G+ SE N + E ++ ++ Q +TL DV Sbjct: 1782 HLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNE 1841 Query: 3345 ISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQG 3404 VS + K+ +++ + + I NL + + L+ + + + D + Sbjct: 1842 TQKKVSEMEQLKKQIKDQSLTLSKLE-IENLNLAQKLHENLEEMKSVMKERDNLRRVEET 1900 Query: 3405 LPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSY---LDVIE 3461 L +R + + LQ K + + ELK R+ K + +D + Sbjct: 1901 LKLERDQLKES----------------LQETKARDLEIQQELKTARMLSKEHKETVDKLR 1944 Query: 3462 QAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFN 3521 + ISE T+ I +I + +D D L + + K +++ + + + + I + Sbjct: 1945 EKISE-KTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLK 2003 Query: 3522 PHYKPE---MQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVL 3578 ++ + MQ+ + NF +T+ E +VAKER +L ++K +L +++F L Sbjct: 2004 KQFEAQNLSMQS-VRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATL 2062 Query: 3579 KELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYR 3638 +E ++AR + + L+ + +H + EK K + +E ++Y Sbjct: 2063 RE----MIAR-DRQNHQVKPEKRLLS--DGQQHLTESLREKCSRIKELLKRYSEMDDHYE 2115 Query: 3639 PAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITY 3698 R SL DL K + F+K + AN + L + Sbjct: 2116 -CLNRLSL------DLEK------------EIEFQKELSMRVKAN---LSLPYLQTKHIE 2153 Query: 3699 SVYMYTARGLFERDKLI-FLAQVTFQVLSMKKE----LNPVELDFLLRFPFKAGVVSPVD 3753 ++ R E +++ L V V +K+E +N E+DF+ + ++ + Sbjct: 2154 KLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQ 2213 Query: 3754 FLQHQGWGGIKALSEMDEFKNLDSDIE-----------GSAKRWKKLVESEAPEKEIFPK 3802 LQ + L ++ +N+D IE S K + V S E F + Sbjct: 2214 HLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLE 2273 Query: 3803 EWKN--------KTALQK----LCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSK 3850 EW N K +QK +C V +R+ + E E RS SK Sbjct: 2274 EWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTE-------FEERSATISK 2326 Query: 3851 SYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDV 3910 +E+ D+++L +K N + SL G +V Sbjct: 2327 EWEQ-------------------DLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTT---- 2363 Query: 3911 AAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPET 3970 Q +N H+ +R +K+ HE + E A E+ Sbjct: 2364 ---------------QDNKNPHVTSRATQLTTEKIRELENSLHE------AKESAMHKES 2402 Query: 3971 HIIPQGILENAIKITNEPPTGMHANLHKA 3999 II ++ +++TN+ + A +H++ Sbjct: 2403 KIIK---MQKELEVTNDIIAKLQAKVHES 2428 Score = 37.4 bits (85), Expect = 0.34 Identities = 182/964 (18%), Positives = 364/964 (37%), Gaps = 195/964 (20%) Query: 579 HKNMPPVAGQLKWSLELQERLEVSMKHLK-HVEHPVMSGAEAK-------LTYQKYDEMM 630 ++ + + + K ELQ+ E HL+ ++ +G + K + +++ E + Sbjct: 1192 YEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETI 1251 Query: 631 ELLRCHREKIYQQWVAGVD-QDCHFNLGQPL-ILRDAASNLIHVNFSKALVAVLREVKYL 688 + LR + Q + D + H L + + +L + L +V + E++ L Sbjct: 1252 DELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELL 1311 Query: 689 NFQQQKEIPDSAESLFSENETFR---KFVGNLELIVGWYNEIKTIVKAVEFLLIKSELEA 745 +Q DS E E R KF + E EIK++ K + L K+ EA Sbjct: 1312 T--EQSTTKDSTTLARIEMERLRLNEKFQESQE-------EIKSLTKERDNL--KTIKEA 1360 Query: 746 IDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQNRMQKAKQNI---EGISQAMKDWSAN 802 ++VK Q + +RE L +Q K +Q++ E ++ K S Sbjct: 1361 LEVKH--------------DQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEM 1406 Query: 803 PLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQAMVAENAELFRADTLSLPWKDY 862 F+ KD+ ALL ++ + L+KR D +++++ E +L R ++ Sbjct: 1407 EQFKPKDS---ALLRIEIEMLGLSKRLQESHD---EMKSVAKEKDDLQRL-------QEV 1453 Query: 863 VIYIDDMVLDEFDQFIRKSLS----FLMDNMVIDESIAPLFEIRMELDEDGL---TFNPT 915 + D + + + + K L + + + E + E+R+ L E T Sbjct: 1454 LQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQ 1513 Query: 916 LEVGSDRGFLALIEGLVNDIY------NVARLIP--------------RLAKDRMNYKMD 955 LE +D+ ++ + +IY N+ ++ R AKD ++ Sbjct: 1514 LEAINDK-----LQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIE 1568 Query: 956 ---LEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAV 1012 LE L E +EE+ ++I +E + Q++ + + D L+E K + Sbjct: 1569 SKMLELTNRLQESQEEIQ-IMIKEKEEMKRVQEALQ----IERDQLKENTKEIVAKMKES 1623 Query: 1013 TAEDLDTWTDDTIPKTPPTLAQFQEQIDSYE--KLYEEVSKCEN---TKVFHGWLQ---- 1063 ++ + +T + + + + +E KL E + EN T++ H L+ Sbjct: 1624 QEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRS 1683 Query: 1064 -CDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGL 1122 R +++ T++ K +L +T L E +K+ M L + + D L Sbjct: 1684 VTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEE-LKIVHMHLKE--HQETIDKL 1740 Query: 1123 VEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLA 1182 + V E+ NM + L+ + + LK ++ EE+ + L E KL Sbjct: 1741 RGI------VSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLR 1794 Query: 1183 IQVKLTVAPLQ------ANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLN 1236 V L N + L+ K Q+ + +H+ Sbjct: 1795 GIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQL---------------------- 1832 Query: 1237 KVFLLKGIMEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTK 1296 + L K + E K V + +QLK K++ D + ++ Sbjct: 1833 -ITLKKDVNETQKK--------VSEMEQLK---------KQIKDQSLTLS---------- 1864 Query: 1297 WKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRE 1356 + +E +++ +K +++ + MK D ++ T+K L+ LQ R+ Sbjct: 1865 --KLEIENLNL-AQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLK--ESLQETKARD 1919 Query: 1357 RHWQQLMQAT------------QVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKES 1404 QQ ++ +++ K+SE+T +Q +L +DE++ + + K Sbjct: 1920 LEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQK-- 1977 Query: 1405 GMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHF 1464 K L+ L + E + H + M + + L V++ N ++K L Sbjct: 1978 ---KELQLL----RVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHES 2030 Query: 1465 LKEV 1468 L+E+ Sbjct: 2031 LEEI 2034 Score = 37.0 bits (84), Expect = 0.44 Identities = 27/131 (20%), Positives = 63/131 (48%), Gaps = 8/131 (6%) Query: 3007 LEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESA 3066 +EQ K + L + E++ +RL+ +++S A + DDL+ + ++E Q E+ Sbjct: 1406 MEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENI 1465 Query: 3067 DQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEAL 3126 +++ E++ ++E + + N++EK ET+++ + L EA+ Sbjct: 1466 KEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEK----ETEISTIQKQL----EAI 1517 Query: 3127 DTLNKNNLTEL 3137 + +N + E+ Sbjct: 1518 NDKLQNKIQEI 1528 >gi|124249396 coiled-coil domain containing 30 [Homo sapiens] Length = 783 Score = 45.8 bits (107), Expect = 0.001 Identities = 46/223 (20%), Positives = 101/223 (45%), Gaps = 29/223 (13%) Query: 1262 YKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDK 1321 Y+ + HR+VR L++ +++ + T + ++Q + K+ + R D+ Sbjct: 411 YQNVDELHRQVRTLQDKENLLEM---------TCSQQQSRIQQQEALLKQLENEKRKYDE 461 Query: 1322 EMKTWDAFVGLDNTVKNVITSLRA----VSELQNPAIR---ERHWQQLMQATQVKFKMSE 1374 +K+ + ++ +LR + +L N +R E+H QQ ++ +VK++++ Sbjct: 462 HVKSNQELSEKLSKLQQEKEALREEYLRLLKLLNVHVRNYNEKHHQQKVKLQKVKYRLTN 521 Query: 1375 ETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTW---------SMMEFQHE 1425 E L D ++ +EDE+ + K KE ++ + A + T ++E + Sbjct: 522 EVELRD---KRINQFEDEIGILQHKIEKEKAIQDQITAQNDTLLLEKRKLQEQVIEQEQL 578 Query: 1426 PHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEV 1468 H T+ S VL E+ Q+Q +L +++ + FL+ + Sbjct: 579 IHSNKWTISSIQSRVLYMDKENKQLQENSLRLTQQIG-FLERI 620 >gi|34577114 cytomatrix protein p110 [Homo sapiens] Length = 957 Score = 43.9 bits (102), Expect = 0.004 Identities = 86/381 (22%), Positives = 155/381 (40%), Gaps = 71/381 (18%) Query: 3004 KTFLEQIKLYQNLLAKKRTELVA---KIERLENG---------LMKLQSTA--------- 3042 KT ++Q+K L+KK +EL+A K+E L N ++K TA Sbjct: 433 KTKIDQLK---QELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQ 489 Query: 3043 SQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINK--- 3099 ++VD L+ +L +E+ L +K + L + G A ++ K + + +E K+ V+ K Sbjct: 490 TEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIE 549 Query: 3100 --------------NVTEKQKACETDLAKAEPALLAAQEAL--------------DTLNK 3131 N+ ++ K+ +TD + + AL +EAL + ++ Sbjct: 550 NLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDR 609 Query: 3132 NNLTELKSFGSP-PDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMG-KVDTFLDSL-- 3187 L E++SF D V A LT + K ++ G K D+ L SL Sbjct: 610 ERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEI 669 Query: 3188 ---KKFDKEHIPEACLKAFKPYQGNPTFDPEF---IRSKSTAAAGLCSWC----INIVRF 3237 +K ++ EA LK + + +PEF I+ A+ C + R Sbjct: 670 AIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRL 729 Query: 3238 YEVYCDVAPKRQALEEANAELAEAQEKLSRIKN-KIAELNANLSNLTSAFEKATAEKIKC 3296 E+ +V ++ ++ AEL + + +N K+A L N L E+++ Sbjct: 730 LEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHN-QQLEKKKNAQLLEEVRR 788 Query: 3297 QQEADATNRVILLANRLVGGL 3317 ++++ A N L L+ L Sbjct: 789 REDSMADNSQHLQIEELMNAL 809 >gi|148762940 DVL-binding protein DAPLE [Homo sapiens] Length = 2028 Score = 42.0 bits (97), Expect = 0.014 Identities = 63/343 (18%), Positives = 139/343 (40%), Gaps = 25/343 (7%) Query: 3007 LEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNES- 3065 LE+ L L K+ +L KIE+L+ L + + + ++ L +L ++ +L+ E+ Sbjct: 489 LEESGLKCGELEKENHQLSKKIEKLQTQLEREKQSNQDLETLSEELIREKEQLQSDMETL 548 Query: 3066 -ADQLIQVVGIEAEKVSKEKA---IADQEEVKVEVINKNVTEKQKACETDLAKAEPALLA 3121 AD+ Q+ +E EK +A + ++ +V E K+V ++ KA + +A L Sbjct: 549 KADKARQIKDLEQEKDHLNRAMWSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQ 608 Query: 3122 AQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVD 3181 + L++ +L + K G + + + L G++ + + ++ Sbjct: 609 LEFEKRQLHR-DLEQAKEKG---ERAEKLERELQRLQEENGRLAR---------KVTSLE 655 Query: 3182 TFLDSLKKFDKE----HIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRF 3237 T + ++ + E + L+ N + E + + L + + + R Sbjct: 656 TATEKVEALEHESQGLQLENRTLRKSLDTLQNVSLQLEGLERDNKQ---LDAENLELRRL 712 Query: 3238 YEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQ 3297 E + K +E N +L +E+L + + + L L +++ +AE ++ Q Sbjct: 713 VETMRFTSTKLAQMERENQQLEREKEELRKNVDLLKALGKKSERLELSYQSVSAENLRLQ 772 Query: 3298 QEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCG 3340 Q ++++ +G L +E +E R L G Sbjct: 773 QSLESSSHKTQTLESELGELEAERQALRRDLEALRLANAQLEG 815 >gi|109255234 centrosomal protein 290kDa [Homo sapiens] Length = 2479 Score = 41.6 bits (96), Expect = 0.018 Identities = 54/281 (19%), Positives = 120/281 (42%), Gaps = 64/281 (22%) Query: 1179 KKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLN-- 1236 KK+ + + LQ NE S++R+ EL++ +E +++ + + + Sbjct: 876 KKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRKENEKQKNELLSMEAEVCEKIGCL 935 Query: 1237 ------KVFLLKGIMEALSKSGGLFEVPVPD--YKQLKACHREVRLLKELWDMVVVVNTS 1288 +F + + + + S L E+ + + Y +L A +R++ L K D ++V TS Sbjct: 936 QRFKEMAIFKIAALQKVVDNSVSLSELELANKQYNELTAKYRDI-LQK---DNMLVQRTS 991 Query: 1289 IEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEM-----------KTWDAFVGLDN--- 1334 N+E ++ + + + S++KE+ + W+ L N Sbjct: 992 ------------NLEHLECENISLKEQVESINKELEITKEKLHTIEQAWEQETKLGNESS 1039 Query: 1335 --------TVKNVITSLRAVSELQNPAIRER----HWQQLMQATQVKFKMSE------ET 1376 T ++++ + ++ L+ + ER H Q++ + + K E ET Sbjct: 1040 MDKAKKSITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELET 1099 Query: 1377 TLADLLQLNLHSYE------DEVRNIVDKAVKESGMEKVLK 1411 A+L ++NL + + DE+ + V KAV ++ +++L+ Sbjct: 1100 KFAELTKINLDAQKVEQMLRDELADSVSKAVSDADRQRILE 1140 Score = 37.0 bits (84), Expect = 0.44 Identities = 31/130 (23%), Positives = 63/130 (48%), Gaps = 13/130 (10%) Query: 3008 EQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQ----VDDLKAK-----LAIQEAE 3058 E+I++ + K E V ++E++ + ++++ Q +D LK + L +QE Sbjct: 230 EKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELT 289 Query: 3059 --LKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAE 3116 LK KNE D ++ V + E+ + D E ++ + + N+ EK K + D K+ Sbjct: 290 DLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKSN 349 Query: 3117 PALLAAQEAL 3126 ++A Q+ + Sbjct: 350 --VMALQQGI 357 Score = 35.4 bits (80), Expect = 1.3 Identities = 51/241 (21%), Positives = 89/241 (36%), Gaps = 40/241 (16%) Query: 3009 QIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQ 3068 Q+ ++ K +++A+ ERL L K A ++ K L I ++ + E + Sbjct: 2187 QLSMHYESKTKGTEKIIAENERLRKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGK 2246 Query: 3069 LIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALL-------A 3121 +Q AE + AD + K V+ + K K ETD+AK ++ Sbjct: 2247 RLQF----AESRGPQLEGADSKSWKSIVVTRMYETKLKELETDIAKKNQSITDLKQLVKE 2302 Query: 3122 AQEALDTLNKNN------LTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKS-----W 3170 A E +NK N + LK + + + +L ++ K+K+ Sbjct: 2303 ATEREQKVNKYNEDLEQQIKILKHVPEGAETEQGLKRELQVLRLANHQLDKEKAELIHQI 2362 Query: 3171 KAAKIMMGKVDTFLDS---------------LKKFDKEHIPEACLKAFKPYQGNPTFDPE 3215 +A K G T D+ + +K+H+ E K K + FDP Sbjct: 2363 EANKDQSGAESTIPDADQLKEKIKDLETQLKMSDLEKQHLKEEIKKLKKELE---NFDPS 2419 Query: 3216 F 3216 F Sbjct: 2420 F 2420 Score = 35.0 bits (79), Expect = 1.7 Identities = 31/126 (24%), Positives = 63/126 (50%), Gaps = 7/126 (5%) Query: 3007 LEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDD--LKAKLAIQEAELKQKNE 3064 LE+++ AK +L K+ +LEN L Q +A D L+ ++ E +L+QK+ Sbjct: 70 LEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDR 129 Query: 3065 SADQLIQVVGIEAEKVSKEKAI----ADQEEVKVEVINKNVTEKQKACETDLAKAEPALL 3120 + + + + E +KV+++ A+ A+ E K+ NK + +K + D+ + + Sbjct: 130 ELEDMEKELEKE-KKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQID 188 Query: 3121 AAQEAL 3126 + +E L Sbjct: 189 SQKETL 194 Score = 32.7 bits (73), Expect = 8.3 Identities = 56/265 (21%), Positives = 106/265 (40%), Gaps = 41/265 (15%) Query: 3560 LEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVE---NLE--TTKHTAS 3614 +E+LK+ L + + K + + L + +AA + T+ E N++ +HT Sbjct: 1727 VERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTR- 1785 Query: 3615 EIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEK 3674 E++ +V + +K+ EA + + R + L LNDLN Q KA+N + + Sbjct: 1786 ELKTQVEDLNENLLKLKEA---LKTSKNRENSLTDNLNDLNN---ELQKKQKAYNKILRE 1839 Query: 3675 AIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPV 3734 + +E+K+++ LT + + L E ++ +V ++ +L Sbjct: 1840 KEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIE--------ELQRKVKKLENQLE-- 1889 Query: 3735 ELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKK------ 3788 G V VD + + L +E K + IEG + K+ Sbjct: 1890 ------------GKVEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKEGEVF 1937 Query: 3789 -LVESEAPEKEIFPKEWKNKTALQK 3812 L + K++F K K K LQ+ Sbjct: 1938 TLTKQLNTLKDLFAKADKEKLTLQR 1962 >gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2 [Homo sapiens] Length = 8749 Score = 41.6 bits (96), Expect = 0.018 Identities = 93/479 (19%), Positives = 182/479 (37%), Gaps = 77/479 (16%) Query: 1151 ELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELK 1210 + L++ +E I +L+ L E WA+ ++ + T+ + + + RK Q Sbjct: 2697 QALRSSNKEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQL---- 2752 Query: 1211 QHEFRERFRREAPFSFSDP-NPYKSLNKVFLLKGIMEALSKSGGLFEVPVPDYKQLKACH 1269 E++ P P L + F+L ++++ +A H Sbjct: 2753 -----EQWMESVDQKIEHPLQPQPGLKEKFVLLDHLQSILSEAE---------DHTRALH 2798 Query: 1270 REVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAF 1329 R + +EL++ T E +K T +++ + DI M ++M+ Sbjct: 2799 RLIAKSRELYE-----KTEDESFKDTAQEELKTQFNDI--------MTVAKEKMRK---- 2841 Query: 1330 VGLDNTVKNVITSLRAVSELQN---PAIRERH-WQQLM---QATQVKFKMSEETTLADLL 1382 ++ VK+ + L AV E + A E H W + ATQ K +E + + Sbjct: 2842 --VEEIVKDHLMYLDAVHEFTDWLHSAKEELHRWSDMSGDSSATQKKLSKIKELIDSREI 2899 Query: 1383 QLNLHSYEDEVRNIVDKAVKESGMEKV---LKALDSTWSMME---FQHEPHPRTGTMMLK 1436 + S + + V + SG E + ++AL + W E FQ T Sbjct: 2900 GASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQ--------TQSCL 2951 Query: 1437 SSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLS------TADSVISIWFEVQR 1490 + V L + + Q + + L F + +W Q+L+ T + ++ W + Q Sbjct: 2952 ENLVSQMALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQE 3011 Query: 1491 TWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLE 1550 L+ +ED+++QL + RF + + +K N + + G NK + Sbjct: 3012 ILDALQKAEPRTEDLKSQL-NELCRFSRDLSTYSGKVSGLIKEYNCLCLQASKGCQNKEQ 3070 Query: 1551 ALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSL 1609 L++ + ++L + +++A DI N + EVS L K+ + L Sbjct: 3071 ILQQRFRKAFRDFQQWLVNAK--------ITTAKCFDIPQNIS---EVSTSLQKIQEFL 3118 Score = 36.6 bits (83), Expect = 0.58 Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 13/113 (11%) Query: 3560 LEQLKANLTKSQNEFKIVLKELED--SLLARLSAASGNFLGDTALVENLETTKHTASEIE 3617 ++ ++ANL +S+ + EL D ++L + + L ++L+E +E Sbjct: 3412 MDSMEANLNESERQHA----ELRDKTTMLGKAKLLNEEVLSYSSLLETIEVKG------- 3460 Query: 3618 EKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNV 3670 + E +T++++ + +E YR ERA L +++ YQ LKAF V Sbjct: 3461 AGMTEHYVTQLELQDLQERYRAIQERAKEAVTKSEKLVRLHQEYQRDLKAFEV 3513 >gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1 [Homo sapiens] Length = 8797 Score = 41.6 bits (96), Expect = 0.018 Identities = 93/479 (19%), Positives = 182/479 (37%), Gaps = 77/479 (16%) Query: 1151 ELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELK 1210 + L++ +E I +L+ L E WA+ ++ + T+ + + + RK Q Sbjct: 2690 QALRSSNKEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQL---- 2745 Query: 1211 QHEFRERFRREAPFSFSDP-NPYKSLNKVFLLKGIMEALSKSGGLFEVPVPDYKQLKACH 1269 E++ P P L + F+L ++++ +A H Sbjct: 2746 -----EQWMESVDQKIEHPLQPQPGLKEKFVLLDHLQSILSEAE---------DHTRALH 2791 Query: 1270 REVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAF 1329 R + +EL++ T E +K T +++ + DI M ++M+ Sbjct: 2792 RLIAKSRELYE-----KTEDESFKDTAQEELKTQFNDI--------MTVAKEKMRK---- 2834 Query: 1330 VGLDNTVKNVITSLRAVSELQN---PAIRERH-WQQLM---QATQVKFKMSEETTLADLL 1382 ++ VK+ + L AV E + A E H W + ATQ K +E + + Sbjct: 2835 --VEEIVKDHLMYLDAVHEFTDWLHSAKEELHRWSDMSGDSSATQKKLSKIKELIDSREI 2892 Query: 1383 QLNLHSYEDEVRNIVDKAVKESGMEKV---LKALDSTWSMME---FQHEPHPRTGTMMLK 1436 + S + + V + SG E + ++AL + W E FQ T Sbjct: 2893 GASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQ--------TQSCL 2944 Query: 1437 SSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLS------TADSVISIWFEVQR 1490 + V L + + Q + + L F + +W Q+L+ T + ++ W + Q Sbjct: 2945 ENLVSQMALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQE 3004 Query: 1491 TWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLE 1550 L+ +ED+++QL + RF + + +K N + + G NK + Sbjct: 3005 ILDALQKAEPRTEDLKSQL-NELCRFSRDLSTYSGKVSGLIKEYNCLCLQASKGCQNKEQ 3063 Query: 1551 ALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSL 1609 L++ + ++L + +++A DI N + EVS L K+ + L Sbjct: 3064 ILQQRFRKAFRDFQQWLVNAK--------ITTAKCFDIPQNIS---EVSTSLQKIQEFL 3111 Score = 36.6 bits (83), Expect = 0.58 Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 13/113 (11%) Query: 3560 LEQLKANLTKSQNEFKIVLKELED--SLLARLSAASGNFLGDTALVENLETTKHTASEIE 3617 ++ ++ANL +S+ + EL D ++L + + L ++L+E +E Sbjct: 3405 MDSMEANLNESERQHA----ELRDKTTMLGKAKLLNEEVLSYSSLLETIEVKG------- 3453 Query: 3618 EKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNV 3670 + E +T++++ + +E YR ERA L +++ YQ LKAF V Sbjct: 3454 AGMTEHYVTQLELQDLQERYRAIQERAKEAVTKSEKLVRLHQEYQRDLKAFEV 3506 >gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] Length = 1979 Score = 41.2 bits (95), Expect = 0.023 Identities = 63/303 (20%), Positives = 131/303 (43%), Gaps = 30/303 (9%) Query: 3044 QVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQE----EVKVEVINK 3099 ++++L+ L ++A ++ E+ +L + +E KE D E + K +V+ K Sbjct: 1348 ELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDVLQK 1407 Query: 3100 NVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTA 3159 + EK + AK++ L + + + +N+N L AV N+ ++IL Sbjct: 1408 LLKEKDLLIK---AKSDQLLSSNENFTNKVNENELLR--------QAVTNLKERILILEM 1456 Query: 3160 PGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPY--QGNPTFDPEFI 3217 GK+ K ++ K + GK +T +L++ + + K F+ + + + + Sbjct: 1457 DIGKL-KGENEKIVETYRGK-ETEYQALQETNMKFSMMLREKEFECHSMKEKALAFEQLL 1514 Query: 3218 RSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQ-----ALEEANAELAEAQEKLSRIKNKI 3272 + K G + +N V+ + V + + AL++ E Q ++ R+++K Sbjct: 1515 KEKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKE 1574 Query: 3273 AELNANL----SNLTSAFEKATAEKIKCQ-QEADATNRVILLANRLVGGL-ASENIRWAE 3326 N L ++L + + T E + + +EA +V +L +LV A EN Sbjct: 1575 FRSNQELERLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQA 1634 Query: 3327 SVE 3329 SV+ Sbjct: 1635 SVQ 1637 >gi|4502395 beclin 1 [Homo sapiens] Length = 450 Score = 40.8 bits (94), Expect = 0.031 Identities = 33/130 (25%), Positives = 56/130 (43%), Gaps = 3/130 (2%) Query: 3005 TFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNE 3064 T L+Q+ N+ + +E LE + + Q+ +LA++E L Q+ E Sbjct: 143 TLLDQLDTQLNVTENECQNYKRCLEILEQ---MNEDDSEQLQMELKELALEEERLIQELE 199 Query: 3065 SADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQE 3124 ++ ++V EKV E DQEE + + +Q + +L E + AQ Sbjct: 200 DVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQT 259 Query: 3125 ALDTLNKNNL 3134 LD L K N+ Sbjct: 260 QLDKLKKTNV 269 >gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] Length = 1417 Score = 39.3 bits (90), Expect = 0.089 Identities = 35/170 (20%), Positives = 80/170 (47%), Gaps = 19/170 (11%) Query: 2981 HTTVNEMS-----RVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGL 3035 H+T E++ R L TE + + K+ L Q++ +++L K + L K +++ Sbjct: 1049 HSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLT 1108 Query: 3036 MKLQSTASQVDDLKAKLAIQEAELKQKN-ESADQLIQVVGIE----------AEKVSKEK 3084 +L+ +++D K +L + LK++N E + QV ++ +K+ K + Sbjct: 1109 AELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLE 1168 Query: 3085 AIADQEEVKVEVINKNV---TEKQKACETDLAKAEPALLAAQEALDTLNK 3131 ++ E++++ NK + +K + + L + E +L ++ + L K Sbjct: 1169 GTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKK 1218 Score = 34.7 bits (78), Expect = 2.2 Identities = 56/290 (19%), Positives = 110/290 (37%), Gaps = 38/290 (13%) Query: 3018 AKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEA 3077 +K +E+ K +L +L+ + AK A E EL +KNE L + E Sbjct: 686 SKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEH 745 Query: 3078 EKVSKEKAIADQEEVKVEVINKNVTEKQ-KACETDLAKAEPALLAAQEALDTLNKNNLTE 3136 EK+ +A ++ K+ + EKQ + E L K + ++ + L ++ + + Sbjct: 746 EKI----CLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICK 801 Query: 3137 LKSFGSPPDAVVNVTAAVMILTAPGGKIPKD--KSWKAAKIMMGKVDTFLDSLKKFDK-- 3192 ++ + +LT G++ K+ K +A K + +V +++ D Sbjct: 802 QH----------HLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSAL 851 Query: 3193 EHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYC---DVAPKRQ 3249 E E + +GN + ++ KS EVYC ++ K Sbjct: 852 EICKEELVLHLNQLEGNKEKFEKQLKKKSE----------------EVYCLQKELKIKNH 895 Query: 3250 ALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQE 3299 +L+E + + Q L + + + + L K + K +QE Sbjct: 896 SLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQE 945 >gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sapiens] Length = 1116 Score = 38.9 bits (89), Expect = 0.12 Identities = 66/350 (18%), Positives = 134/350 (38%), Gaps = 50/350 (14%) Query: 3017 LAKKRTELVA---KIERLEN---------GLMKLQSTA---------SQVDDLKAKLAIQ 3055 L++K TEL+A K+E L N ++K TA ++VD L+ +L + Sbjct: 475 LSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEK 534 Query: 3056 EAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKA 3115 E L +K + + + G +A ++ K + D +E KV V+ K + Q+ L Sbjct: 535 ETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQE----QLRDK 590 Query: 3116 EPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKS------ 3169 E + + +E + +L + + + +A+ + L + ++K Sbjct: 591 EKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNY 650 Query: 3170 WKAAKIMMGKVDTFLDSLKKFD------KEHIPEACLKAFKPYQGNPTFDPEFIRSKSTA 3223 K K + KV L + + KEH K T + + K Sbjct: 651 KKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEE- 709 Query: 3224 AAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLT 3283 C+ + + + A + +A E + + + +++R K++ ++ A + L Sbjct: 710 -------CLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 762 Query: 3284 SAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRS 3333 ++ EK ++ R + N+ V N++ E VE +S Sbjct: 763 EILKEVENEKNDKDKKIAELERQVKDQNKKVA-----NLKHKEQVEKKKS 807 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 158,629,306 Number of Sequences: 37866 Number of extensions: 6923556 Number of successful extensions: 20388 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 135 Number of HSP's that attempted gapping in prelim test: 18963 Number of HSP's gapped (non-prelim): 1219 length of query: 4485 length of database: 18,247,518 effective HSP length: 123 effective length of query: 4362 effective length of database: 13,590,000 effective search space: 59279580000 effective search space used: 59279580000 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.