Guide to the Human Genome
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Search of human proteins with 239751459

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
         (4485 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s...  8953   0.0  
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s...  8947   0.0  
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s...  8792   0.0  
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap...  5712   0.0  
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]          5294   0.0  
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]         2287   0.0  
gi|75677365 dynein heavy chain domain 3 [Homo sapiens]               2162   0.0  
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]    1989   0.0  
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]          1981   0.0  
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]          1946   0.0  
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]           1921   0.0  
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]    1896   0.0  
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]           1893   0.0  
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]        1344   0.0  
gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap...  1213   0.0  
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]     1160   0.0  
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]     954   0.0  
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H...   701   0.0  
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]     158   1e-37
gi|71061468 centromere protein E [Homo sapiens]                        48   3e-04
gi|124249396 coiled-coil domain containing 30 [Homo sapiens]           46   0.001
gi|34577114 cytomatrix protein p110 [Homo sapiens]                     44   0.004
gi|148762940 DVL-binding protein DAPLE [Homo sapiens]                  42   0.014
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 42   0.018
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    42   0.018
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    42   0.018
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]     41   0.023
gi|4502395 beclin 1 [Homo sapiens]                                     41   0.031
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   39   0.089
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    39   0.12 

>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
            sapiens]
          Length = 4485

 Score = 8953 bits (23232), Expect = 0.0
 Identities = 4485/4485 (100%), Positives = 4485/4485 (100%)

Query: 1    MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60
            MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG
Sbjct: 1    MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60

Query: 61   MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120
            MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL
Sbjct: 61   MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120

Query: 121  LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180
            LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER
Sbjct: 121  LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180

Query: 181  IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC 240
            IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC
Sbjct: 181  IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC 240

Query: 241  IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300
            IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME
Sbjct: 241  IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300

Query: 301  QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360
            QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK
Sbjct: 301  QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360

Query: 361  GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420
            GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF
Sbjct: 361  GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420

Query: 421  FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480
            FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD
Sbjct: 421  FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480

Query: 481  PGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAE 540
            PGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAE
Sbjct: 481  PGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAE 540

Query: 541  VAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLE 600
            VAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLE
Sbjct: 541  VAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLE 600

Query: 601  VSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPL 660
            VSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPL
Sbjct: 601  VSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPL 660

Query: 661  ILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELI 720
            ILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELI
Sbjct: 661  ILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELI 720

Query: 721  VGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQN 780
            VGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQN
Sbjct: 721  VGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQN 780

Query: 781  RMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQ 840
            RMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQ
Sbjct: 781  RMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQ 840

Query: 841  AMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFE 900
            AMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFE
Sbjct: 841  AMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFE 900

Query: 901  IRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMNYKMDLEDNT 960
            IRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMNYKMDLEDNT
Sbjct: 901  IRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMNYKMDLEDNT 960

Query: 961  DLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTW 1020
            DLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTW
Sbjct: 961  DLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTW 1020

Query: 1021 TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW 1080
            TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW
Sbjct: 1021 TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW 1080

Query: 1081 GFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATD 1140
            GFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATD
Sbjct: 1081 GFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATD 1140

Query: 1141 NMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSIL 1200
            NMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSIL
Sbjct: 1141 NMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSIL 1200

Query: 1201 RRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKVFLLKGIMEALSKSGGLFEVPVP 1260
            RRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKVFLLKGIMEALSKSGGLFEVPVP
Sbjct: 1201 RRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKVFLLKGIMEALSKSGGLFEVPVP 1260

Query: 1261 DYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLD 1320
            DYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLD
Sbjct: 1261 DYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLD 1320

Query: 1321 KEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLAD 1380
            KEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLAD
Sbjct: 1321 KEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLAD 1380

Query: 1381 LLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEV 1440
            LLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEV
Sbjct: 1381 LLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEV 1440

Query: 1441 LVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFI 1500
            LVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFI
Sbjct: 1441 LVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFI 1500

Query: 1501 GSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICE 1560
            GSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICE
Sbjct: 1501 GSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICE 1560

Query: 1561 KALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASD 1620
            KALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASD
Sbjct: 1561 KALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASD 1620

Query: 1621 KPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPR 1680
            KPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPR
Sbjct: 1621 KPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPR 1680

Query: 1681 EQWILDYPAQIWWTTEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRM 1740
            EQWILDYPAQIWWTTEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRM
Sbjct: 1681 EQWILDYPAQIWWTTEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRM 1740

Query: 1741 KIMTICTIDVHARDVVAKMIVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYL 1800
            KIMTICTIDVHARDVVAKMIVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYL
Sbjct: 1741 KIMTICTIDVHARDVVAKMIVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYL 1800

Query: 1801 GNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCS 1860
            GNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCS
Sbjct: 1801 GNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCS 1860

Query: 1861 EQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLG 1920
            EQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLG
Sbjct: 1861 EQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLG 1920

Query: 1921 EIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEAR 1980
            EIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEAR
Sbjct: 1921 EIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEAR 1980

Query: 1981 LLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDF 2040
            LLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDF
Sbjct: 1981 LLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDF 2040

Query: 2041 NIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQL 2100
            NIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQL
Sbjct: 2041 NIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQL 2100

Query: 2101 EELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPV 2160
            EELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPV
Sbjct: 2101 EELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPV 2160

Query: 2161 TREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIP 2220
            TREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIP
Sbjct: 2161 TREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIP 2220

Query: 2221 LNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMIL 2280
            LNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMIL
Sbjct: 2221 LNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMIL 2280

Query: 2281 FDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFT 2340
            FDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFT
Sbjct: 2281 FDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFT 2340

Query: 2341 CFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVP 2400
            CFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVP
Sbjct: 2341 CFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVP 2400

Query: 2401 SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNT 2460
            SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNT
Sbjct: 2401 SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNT 2460

Query: 2461 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT 2520
            DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT
Sbjct: 2461 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT 2520

Query: 2521 VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSF 2580
            VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSF
Sbjct: 2521 VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSF 2580

Query: 2581 PGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVF 2640
            PGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVF
Sbjct: 2581 PGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVF 2640

Query: 2641 NLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTK 2700
            NLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTK
Sbjct: 2641 NLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTK 2700

Query: 2701 KFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMNLV 2760
            KFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMNLV
Sbjct: 2701 KFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMNLV 2760

Query: 2761 LFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIP 2820
            LFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIP
Sbjct: 2761 LFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIP 2820

Query: 2821 DLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENII 2880
            DLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENII
Sbjct: 2821 DLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENII 2880

Query: 2881 SSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAI 2940
            SSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAI
Sbjct: 2881 SSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAI 2940

Query: 2941 DWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNY 3000
            DWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNY
Sbjct: 2941 DWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNY 3000

Query: 3001 TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELK 3060
            TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELK
Sbjct: 3001 TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELK 3060

Query: 3061 QKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALL 3120
            QKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALL
Sbjct: 3061 QKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALL 3120

Query: 3121 AAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKV 3180
            AAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKV
Sbjct: 3121 AAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKV 3180

Query: 3181 DTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEV 3240
            DTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEV
Sbjct: 3181 DTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEV 3240

Query: 3241 YCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEA 3300
            YCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEA
Sbjct: 3241 YCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEA 3300

Query: 3301 DATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYR 3360
            DATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYR
Sbjct: 3301 DATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYR 3360

Query: 3361 NELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGN 3420
            NELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGN
Sbjct: 3361 NELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGN 3420

Query: 3421 TERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVD 3480
            TERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVD
Sbjct: 3421 TERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVD 3480

Query: 3481 PVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT 3540
            PVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT
Sbjct: 3481 PVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT 3540

Query: 3541 RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT 3600
            RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT
Sbjct: 3541 RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT 3600

Query: 3601 ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV 3660
            ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV
Sbjct: 3601 ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV 3660

Query: 3661 YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV 3720
            YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV
Sbjct: 3661 YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV 3720

Query: 3721 TFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIE 3780
            TFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIE
Sbjct: 3721 TFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIE 3780

Query: 3781 GSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKF 3840
            GSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKF
Sbjct: 3781 GSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKF 3840

Query: 3841 VEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQ 3900
            VEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQ
Sbjct: 3841 VEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQ 3900

Query: 3901 EVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGSHEDYRVFI 3960
            EVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGSHEDYRVFI
Sbjct: 3901 EVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGSHEDYRVFI 3960

Query: 3961 SAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCM 4020
            SAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCM
Sbjct: 3961 SAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCM 4020

Query: 4021 LFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFG 4080
            LFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFG
Sbjct: 4021 LFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFG 4080

Query: 4081 EIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLP 4140
            EIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLP
Sbjct: 4081 EIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLP 4140

Query: 4141 PESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSE 4200
            PESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSE
Sbjct: 4141 PESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSE 4200

Query: 4201 RKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECER 4260
            RKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECER
Sbjct: 4201 RKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECER 4260

Query: 4261 MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY 4320
            MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY
Sbjct: 4261 MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY 4320

Query: 4321 ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT 4380
            ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT
Sbjct: 4321 ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT 4380

Query: 4381 KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME 4440
            KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME
Sbjct: 4381 KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME 4440

Query: 4441 TKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV 4485
            TKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV
Sbjct: 4441 TKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV 4485


>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
            sapiens]
          Length = 4485

 Score = 8947 bits (23217), Expect = 0.0
 Identities = 4481/4485 (99%), Positives = 4483/4485 (99%)

Query: 1    MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60
            MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG
Sbjct: 1    MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60

Query: 61   MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120
            MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL
Sbjct: 61   MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120

Query: 121  LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180
            LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER
Sbjct: 121  LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180

Query: 181  IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC 240
            IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWD RLLNLKC
Sbjct: 181  IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDTRLLNLKC 240

Query: 241  IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300
            IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME
Sbjct: 241  IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300

Query: 301  QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360
            QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK
Sbjct: 301  QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360

Query: 361  GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420
            GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF
Sbjct: 361  GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420

Query: 421  FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480
            FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD
Sbjct: 421  FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480

Query: 481  PGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAE 540
            PGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAE
Sbjct: 481  PGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAE 540

Query: 541  VAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLE 600
            VAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLE
Sbjct: 541  VAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLE 600

Query: 601  VSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPL 660
            VSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPL
Sbjct: 601  VSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPL 660

Query: 661  ILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELI 720
            ILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELI
Sbjct: 661  ILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELI 720

Query: 721  VGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQN 780
            VGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQN
Sbjct: 721  VGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQN 780

Query: 781  RMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQ 840
            RMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQ
Sbjct: 781  RMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQ 840

Query: 841  AMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFE 900
            AMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFE
Sbjct: 841  AMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFE 900

Query: 901  IRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMNYKMDLEDNT 960
            IRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMNYKMDLEDNT
Sbjct: 901  IRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMNYKMDLEDNT 960

Query: 961  DLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTW 1020
            DLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTW
Sbjct: 961  DLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTW 1020

Query: 1021 TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW 1080
            TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW
Sbjct: 1021 TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW 1080

Query: 1081 GFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATD 1140
            GFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATD
Sbjct: 1081 GFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATD 1140

Query: 1141 NMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSIL 1200
            NMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSIL
Sbjct: 1141 NMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSIL 1200

Query: 1201 RRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKVFLLKGIMEALSKSGGLFEVPVP 1260
            RRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKVFLLKGIMEALSKSGGLFEVPVP
Sbjct: 1201 RRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKVFLLKGIMEALSKSGGLFEVPVP 1260

Query: 1261 DYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLD 1320
            DYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLD
Sbjct: 1261 DYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLD 1320

Query: 1321 KEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLAD 1380
            KEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLAD
Sbjct: 1321 KEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLAD 1380

Query: 1381 LLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEV 1440
            LLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEV
Sbjct: 1381 LLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEV 1440

Query: 1441 LVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFI 1500
            LVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFI
Sbjct: 1441 LVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFI 1500

Query: 1501 GSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICE 1560
            GSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICE
Sbjct: 1501 GSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICE 1560

Query: 1561 KALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASD 1620
            KALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASD
Sbjct: 1561 KALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASD 1620

Query: 1621 KPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPR 1680
            KPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPR
Sbjct: 1621 KPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPR 1680

Query: 1681 EQWILDYPAQIWWTTEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRM 1740
            EQWILDYPAQIWWTTEVGLAFARLEEGYENAI+DYNKKQISQLNVLITLL+GNLNAGDRM
Sbjct: 1681 EQWILDYPAQIWWTTEVGLAFARLEEGYENAIRDYNKKQISQLNVLITLLMGNLNAGDRM 1740

Query: 1741 KIMTICTIDVHARDVVAKMIVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYL 1800
            KIMTICTIDVHARDVVAKMIVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYL
Sbjct: 1741 KIMTICTIDVHARDVVAKMIVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYL 1800

Query: 1801 GNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCS 1860
            GNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCS
Sbjct: 1801 GNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCS 1860

Query: 1861 EQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLG 1920
            EQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLG
Sbjct: 1861 EQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLG 1920

Query: 1921 EIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEAR 1980
            EIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEAR
Sbjct: 1921 EIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEAR 1980

Query: 1981 LLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDF 2040
            LLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDF
Sbjct: 1981 LLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDF 2040

Query: 2041 NIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQL 2100
            NIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQL
Sbjct: 2041 NIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQL 2100

Query: 2101 EELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPV 2160
            EELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPV
Sbjct: 2101 EELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPV 2160

Query: 2161 TREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIP 2220
            TREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIP
Sbjct: 2161 TREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIP 2220

Query: 2221 LNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMIL 2280
            LNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMIL
Sbjct: 2221 LNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMIL 2280

Query: 2281 FDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFT 2340
            FDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFT
Sbjct: 2281 FDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFT 2340

Query: 2341 CFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVP 2400
            CFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVP
Sbjct: 2341 CFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVP 2400

Query: 2401 SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNT 2460
            SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNT
Sbjct: 2401 SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNT 2460

Query: 2461 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT 2520
            DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT
Sbjct: 2461 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT 2520

Query: 2521 VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSF 2580
            VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSF
Sbjct: 2521 VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSF 2580

Query: 2581 PGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVF 2640
            PGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVF
Sbjct: 2581 PGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVF 2640

Query: 2641 NLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTK 2700
            NLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTK
Sbjct: 2641 NLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTK 2700

Query: 2701 KFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMNLV 2760
            KFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMNLV
Sbjct: 2701 KFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMNLV 2760

Query: 2761 LFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIP 2820
            LFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIP
Sbjct: 2761 LFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIP 2820

Query: 2821 DLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENII 2880
            DLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENII
Sbjct: 2821 DLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENII 2880

Query: 2881 SSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAI 2940
            SSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAI
Sbjct: 2881 SSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAI 2940

Query: 2941 DWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNY 3000
            DWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNY
Sbjct: 2941 DWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNY 3000

Query: 3001 TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELK 3060
            TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELK
Sbjct: 3001 TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELK 3060

Query: 3061 QKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALL 3120
            QKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALL
Sbjct: 3061 QKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALL 3120

Query: 3121 AAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKV 3180
            AAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKV
Sbjct: 3121 AAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKV 3180

Query: 3181 DTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEV 3240
            DTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEV
Sbjct: 3181 DTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEV 3240

Query: 3241 YCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEA 3300
            YCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEA
Sbjct: 3241 YCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEA 3300

Query: 3301 DATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYR 3360
            DATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYR
Sbjct: 3301 DATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYR 3360

Query: 3361 NELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGN 3420
            NELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGN
Sbjct: 3361 NELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGN 3420

Query: 3421 TERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVD 3480
            TERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVD
Sbjct: 3421 TERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVD 3480

Query: 3481 PVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT 3540
            PVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT
Sbjct: 3481 PVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT 3540

Query: 3541 RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT 3600
            RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT
Sbjct: 3541 RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT 3600

Query: 3601 ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV 3660
            ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV
Sbjct: 3601 ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV 3660

Query: 3661 YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV 3720
            YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV
Sbjct: 3661 YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV 3720

Query: 3721 TFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIE 3780
            TFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIE
Sbjct: 3721 TFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIE 3780

Query: 3781 GSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKF 3840
            GSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKF
Sbjct: 3781 GSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKF 3840

Query: 3841 VEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQ 3900
            VEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQ
Sbjct: 3841 VEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQ 3900

Query: 3901 EVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGSHEDYRVFI 3960
            EVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLE YSTGSHEDYRVFI
Sbjct: 3901 EVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLEHYSTGSHEDYRVFI 3960

Query: 3961 SAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCM 4020
            SAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCM
Sbjct: 3961 SAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCM 4020

Query: 4021 LFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFG 4080
            LFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFG
Sbjct: 4021 LFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFG 4080

Query: 4081 EIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLP 4140
            EIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLP
Sbjct: 4081 EIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLP 4140

Query: 4141 PESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSE 4200
            PESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSE
Sbjct: 4141 PESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSE 4200

Query: 4201 RKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECER 4260
            RKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECER
Sbjct: 4201 RKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECER 4260

Query: 4261 MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY 4320
            MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY
Sbjct: 4261 MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY 4320

Query: 4321 ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT 4380
            ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT
Sbjct: 4321 ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT 4380

Query: 4381 KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME 4440
            KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME
Sbjct: 4381 KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME 4440

Query: 4441 TKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV 4485
            TKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV
Sbjct: 4441 TKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV 4485


>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
            sapiens]
          Length = 4470

 Score = 8792 bits (22813), Expect = 0.0
 Identities = 4433/4511 (98%), Positives = 4441/4511 (98%), Gaps = 67/4511 (1%)

Query: 1    MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60
            MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG
Sbjct: 1    MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAG 60

Query: 61   MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120
            MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL
Sbjct: 61   MIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL 120

Query: 121  LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180
            LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER
Sbjct: 121  LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMER 180

Query: 181  IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC 240
            IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC
Sbjct: 181  IPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKC 240

Query: 241  IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300
            IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME
Sbjct: 241  IHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEME 300

Query: 301  QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360
            QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK
Sbjct: 301  QADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLK 360

Query: 361  GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420
            GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF
Sbjct: 361  GLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSF 420

Query: 421  FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480
            FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD
Sbjct: 421  FQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLD 480

Query: 481  PGDS------------NFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMC 528
            PGDS            NFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMC
Sbjct: 481  PGDSVGPRAGLDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMC 540

Query: 529  GGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQ 588
            GGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQ
Sbjct: 541  GGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQ 600

Query: 589  LKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGV 648
            LKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGV
Sbjct: 601  LKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGV 660

Query: 649  DQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENE 708
            DQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENE
Sbjct: 661  DQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENE 720

Query: 709  TFRKFVGNLELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYI 768
            TFRKFVGNLELIVGWYNE+   +KAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYI
Sbjct: 721  TFRKFVGNLELIVGWYNEV---MKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYI 777

Query: 769  QEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKR 828
            QEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKR
Sbjct: 778  QEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKR 837

Query: 829  YAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDN 888
            YAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDN
Sbjct: 838  YAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDN 897

Query: 889  MVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKD 948
            MVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKD
Sbjct: 898  MVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKD 957

Query: 949  RMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIY 1008
            RMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIY
Sbjct: 958  RMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIY 1017

Query: 1009 GCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP 1068
            GCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP
Sbjct: 1018 GCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP 1077

Query: 1069 FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGH 1128
            FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGH
Sbjct: 1078 FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGH 1137

Query: 1129 LMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLT 1188
            LMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLT
Sbjct: 1138 LMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLT 1197

Query: 1189 VAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNK----VFLLKGI 1244
            VAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNK    +  ++GI
Sbjct: 1198 VAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAMEGI 1257

Query: 1245 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ 1304
            MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ
Sbjct: 1258 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ 1317

Query: 1305 MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ 1364
            MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ
Sbjct: 1318 MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ 1377

Query: 1365 ATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQH 1424
            ATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQH
Sbjct: 1378 ATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQH 1437

Query: 1425 EPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISI 1484
            EPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISI
Sbjct: 1438 EPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISI 1497

Query: 1485 WFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPG 1544
            WFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPG
Sbjct: 1498 WFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPG 1557

Query: 1545 LYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSK 1604
            LYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSK
Sbjct: 1558 LYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSK 1617

Query: 1605 LFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTL 1664
            LFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTL
Sbjct: 1618 LFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTL 1677

Query: 1665 RHEIPEAVVTYEEKPREQWILDYPAQ-------IWWTTEVGLAFARLEEGYENAIKDYNK 1717
            RHEIPEAVVTYEEKPREQWILDYPAQ       IWWTTEVGLAFARLEEGYENAI+DYNK
Sbjct: 1678 RHEIPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNK 1737

Query: 1718 KQISQLNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMIV---ESSQAFTWQAQLR 1774
            KQISQLNVLITLL+GNLNAGDRMKIMTICTIDVHARDVVAKMIV   ESSQAFTWQAQLR
Sbjct: 1738 KQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLR 1797

Query: 1775 HRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGP 1834
            HRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGP
Sbjct: 1798 HRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGP 1857

Query: 1835 AGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEV 1894
            AGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEV
Sbjct: 1858 AGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEV 1917

Query: 1895 LSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFR 1954
            LSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFR
Sbjct: 1918 LSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFR 1977

Query: 1955 PCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVL 2014
            PCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVL
Sbjct: 1978 PCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVL 2037

Query: 2015 VVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF 2074
            VVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF
Sbjct: 2038 VVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF 2097

Query: 2075 EKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL 2134
            EKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL
Sbjct: 2098 EKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL 2157

Query: 2135 KRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDID 2194
            KRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDID
Sbjct: 2158 KRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDID 2217

Query: 2195 PMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPAD 2254
            PMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPAD
Sbjct: 2218 PMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPAD 2277

Query: 2255 LGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYL 2314
            LGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYL
Sbjct: 2278 LGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYL 2337

Query: 2315 LECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKF 2374
            LECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKF
Sbjct: 2338 LECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKF 2397

Query: 2375 PSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKS 2434
            PSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKS
Sbjct: 2398 PSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKS 2457

Query: 2435 WPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRN 2494
            WPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRN
Sbjct: 2458 WPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRN 2517

Query: 2495 YGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVA 2554
            YGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVA
Sbjct: 2518 YGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVA 2577

Query: 2555 CMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQL 2614
            CMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQL
Sbjct: 2578 CMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQL 2637

Query: 2615 VAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHET 2674
            VAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHET
Sbjct: 2638 VAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHET 2697

Query: 2675 ERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVT 2734
            ERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVT
Sbjct: 2698 ERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVT 2757

Query: 2735 DMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQ 2794
            DMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQ
Sbjct: 2758 DMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQ 2817

Query: 2795 SLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQF 2854
            SLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQF
Sbjct: 2818 SLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQF 2877

Query: 2855 LVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVI 2914
            LVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVI
Sbjct: 2878 LVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVI 2937

Query: 2915 LCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASIS 2974
            LCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIP  +KASIS
Sbjct: 2938 LCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIP-VIKASIS 2996

Query: 2975 FFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENG 3034
            FFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENG
Sbjct: 2997 FFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENG 3056

Query: 3035 LMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKV 3094
            LMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKV
Sbjct: 3057 LMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKV 3116

Query: 3095 EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAV 3154
            EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAV
Sbjct: 3117 EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAV 3176

Query: 3155 MILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDP 3214
            MILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDP
Sbjct: 3177 MILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDP 3236

Query: 3215 EFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE 3274
            EFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE
Sbjct: 3237 EFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE 3296

Query: 3275 LNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQ 3334
            LNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQ
Sbjct: 3297 LNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQ 3356

Query: 3335 GVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDD 3394
            GVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDD
Sbjct: 3357 GVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDD 3416

Query: 3395 ADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQK 3454
            ADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQK
Sbjct: 3417 ADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQK 3476

Query: 3455 SYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLI 3514
            SYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLI
Sbjct: 3477 SYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLI 3536

Query: 3515 LHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEF 3574
            LHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEF
Sbjct: 3537 LHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEF 3596

Query: 3575 KIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEAR 3634
            KIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEAR
Sbjct: 3597 KIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEAR 3656

Query: 3635 ENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTD 3694
            ENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTD
Sbjct: 3657 ENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTD 3716

Query: 3695 EITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDF 3754
            EITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDF
Sbjct: 3717 EITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDF 3776

Query: 3755 LQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLC 3814
            LQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLC
Sbjct: 3777 LQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLC 3836

Query: 3815 MVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKD 3874
            MVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKD
Sbjct: 3837 MVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKD 3896

Query: 3875 VEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLV 3934
            VEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ        NIHLV
Sbjct: 3897 VEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ--------NIHLV 3948

Query: 3935 ARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHA 3994
            ARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHA
Sbjct: 3949 ARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHA 4008

Query: 3995 NLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLT 4054
            NLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLT
Sbjct: 4009 NLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLT 4068

Query: 4055 ISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDV 4114
            ISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDV
Sbjct: 4069 ISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDV 4128

Query: 4115 LLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQP 4174
            LLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQP
Sbjct: 4129 LLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQP 4188

Query: 4175 KETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPET 4234
            KETDSGAGTGVSREEK                             VKAVLDDILEKIPET
Sbjct: 4189 KETDSGAGTGVSREEK-----------------------------VKAVLDDILEKIPET 4219

Query: 4235 FNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLST 4294
            FNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLST
Sbjct: 4220 FNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLST 4279

Query: 4295 ALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSF 4354
            ALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSF
Sbjct: 4280 ALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSF 4339

Query: 4355 LTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVI 4414
            LTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVI
Sbjct: 4340 LTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVI 4399

Query: 4415 AEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKW 4474
            AEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKW
Sbjct: 4400 AEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKW 4459

Query: 4475 ILAAVALLLQV 4485
            ILAAVALLLQV
Sbjct: 4460 ILAAVALLLQV 4470


>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
          Length = 4486

 Score = 5712 bits (14817), Expect = 0.0
 Identities = 2806/4506 (62%), Positives = 3513/4506 (77%), Gaps = 67/4506 (1%)

Query: 6    DVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQ----VLVLTLNAAGM 61
            D RL  L    ++ L+     W +  G+ E   L   F  +   +    +LV+     G+
Sbjct: 22   DRRLRLLGTYVAMSLRPAAGAWERCAGSAEAEQLLQAFLGRDAAEGPRPLLVVRPGPRGL 81

Query: 62   II-PCLGF-PQS--LKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVL 117
             I P L   P+S    +K ++F++T  E    D++R  ++ GD+   P++ L A+  EV+
Sbjct: 82   AIRPGLEVGPESGLAGAKALFFLRTGPEPPGPDSFRGAVVCGDLPAAPLEHLAALFSEVV 141

Query: 118  SSLLNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLES 177
              +L   +N   WP ++ ED+ +  H L+ ++ V+  ++KGKTLLP+P     ++     
Sbjct: 142  LPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFADSK 201

Query: 178  MERIPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLN 237
             E +  S+D  +++AIE+ +I WS+Q++ VL ++S+Q LL G +P P+VE EFW +R  +
Sbjct: 202  SETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKSRYED 261

Query: 238  LKCIHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLE 297
            LK I+ QL    V  + ++L+K +S Y+PA + +Y +V   L EA DI ++L PL+  LE
Sbjct: 262  LKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQRHLE 321

Query: 298  EMEQADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEE 357
             +E A+F  +   +  +L  +C IWAT + Y +P R+ V+LQE CN +I+    +LSPE+
Sbjct: 322  ALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQEICNLLIQQASNYLSPED 381

Query: 358  VLKGLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVP-WEFPSSLAFSR 416
            +L+    E+EE    + +  + L    Q +     N+  +FK+ + V  W+F SSL F R
Sbjct: 382  LLRS---EVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQEVKEWDFQSSLVFVR 438

Query: 417  INSFFQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKY 476
            ++ F  ++  +E L KTA++F KL K+E  GVRGN L   V ++++E  E+ ++ +    
Sbjct: 439  LDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQEMYRLLSGSSS 498

Query: 477  DPLDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPL 536
            D L    ++F+ D ++F  K++DLDRRL TIF Q FDD   ++ + KLL + G L+ERPL
Sbjct: 499  DCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHAFKLLDIAGNLLERPL 558

Query: 537  ILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQ 596
            +  + + +Y V++++F+ +LD  +++Y   +    E     +HKNMP VAG L+W+ EL+
Sbjct: 559  VARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVHKNMPTVAGGLRWAQELR 618

Query: 597  ERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNL 656
            +R++    +   + HP M  AE K   QKY++M+ LL  +  ++Y+ W   V +   +NL
Sbjct: 619  QRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYETRLYEDWCRTVSEKSQYNL 678

Query: 657  GQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGN 716
             QPL+ RD  +  I +NF+  L++VL+E+ YL  ++ K +P++A ++FS  + +R+ V N
Sbjct: 679  SQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPETAAAMFSSRDFYRQLVAN 738

Query: 717  LELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILH 776
            LEL+  WYN++   +  VEF L++ EL+ ID++L +AE TL W  EG+  Y+ E+   +H
Sbjct: 739  LELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKTEGICDYVTEITSSIH 798

Query: 777  NLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAG 836
            +L+ R+QK K N+E I   MK W   P+F+ KD K+E+LL LD R   + K Y  ++++G
Sbjct: 799  DLEQRIQKTKDNVEEIQNIMKTW-VTPIFKTKDGKRESLLSLDDRHDRMEKYYNLIKESG 857

Query: 837  VKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIA 896
            +KI A+V EN  LF AD  S  WK YV  ID+++L+ F   I  SL +L++N      + 
Sbjct: 858  LKIHALVQENLGLFSADPTSNIWKTYVNSIDNLLLNGFFLAIECSLKYLLENTECKAGLT 917

Query: 897  PLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDR--MNYKM 954
            P+FE ++ L    L F P+LE G   GF  ++EGL+  I+ +  L+PRL+      +Y++
Sbjct: 918  PIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPSLVPRLSPQNGSPHYQV 977

Query: 955  DLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTA 1014
            DL+   DL  MR  +   V   M     YQ +F +YSYL+ ++ +E +  FL+YG  +T 
Sbjct: 978  DLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVEDRKEVLGQFLLYGHILTP 1037

Query: 1015 EDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALL 1074
            E+++   +D IP+ PP L+QF+ QIDSYE LYEEV + E  KVF GW++ D RPFK +LL
Sbjct: 1038 EEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKVFDGWMKIDIRPFKASLL 1097

Query: 1075 STIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKE 1134
            + I+RW  +FK+HL +HVT+SLA+L+AF+K +  GL K +++GD+ GLVE+MGHLM VKE
Sbjct: 1098 NIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKGDFQGLVEIMGHLMAVKE 1157

Query: 1135 RQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQA 1194
            RQ+ TD MFEPLKQTIELLKTY +E+PE +  +L+ELPE W N KK+AI VK  VAPLQA
Sbjct: 1158 RQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNIKKVAITVKQQVAPLQA 1217

Query: 1195 NEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLN----KVFLLKGIMEALSK 1250
            NEV++LR++C  F+ +Q +F E+F +EAPF F   +P++ L+    ++  ++  M ++S+
Sbjct: 1218 NEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDARHIEIQQMESTMASISE 1277

Query: 1251 SGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCK 1310
            S  LFEV VPDYKQL+ C +EV  LKELWD + +V +SI  W+TT W++INVE M+++CK
Sbjct: 1278 SASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECK 1337

Query: 1311 KFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKF 1370
            +FA+ +R+LDKE++ WDAF GL++TV N ++SLRAV+ELQNPAIRERHW+QLMQAT V F
Sbjct: 1338 QFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSF 1397

Query: 1371 KMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRT 1430
             M ++TTLA LLQL LH YEDEVR IVDKA KE GMEK LK L +TW+ MEFQ+EPHPRT
Sbjct: 1398 TMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRT 1457

Query: 1431 GTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQR 1490
               +L S E L+E LEDNQVQLQNL+MSKY+A FL+EV+ WQ+KLST D+VISIWFEVQR
Sbjct: 1458 NVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQR 1517

Query: 1491 TWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLE 1550
            TW+HLESIF GSEDIR QLP DS+RF+ I+ +FK L  DA K PNVV+ T+KPGLY KLE
Sbjct: 1518 TWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLE 1577

Query: 1551 ALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLC 1610
             ++  L +CEKALAEYL+TKRLAFPRFYF+SS+DLLDILSNG  P +V RHLSKLFD++ 
Sbjct: 1578 DIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMA 1637

Query: 1611 KLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPE 1670
            K++F+LDAS +P K  LGMYSKE+EY+ F + CD SGQVE+WLN VL  M +T+RHE+ E
Sbjct: 1638 KMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTE 1697

Query: 1671 AVVTYEEKPREQWILDYPAQ-------IWWTTEVGLAFARLEEGYENAIKDYNKKQISQL 1723
             V  YEEKPREQW+ D+PAQ       IWWTTEVG+AFARLEEGYE+A+KDY KKQ++QL
Sbjct: 1698 GVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQL 1757

Query: 1724 NVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEE 1780
              LIT+LIG L+ GDR KIMTICTIDVHARDVVAKMI   V+++QAF W +QLRHRWD+E
Sbjct: 1758 KTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDE 1817

Query: 1781 KRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKT 1840
             +HCFANICDAQ  YSYEYLGNTPRLVITPLTDRCYITLTQSLHL M GAPAGPAGTGKT
Sbjct: 1818 VKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKT 1877

Query: 1841 ETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAV 1900
            ETTKDLGRALG +VYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSV+AV
Sbjct: 1878 ETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAV 1937

Query: 1901 QVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVV 1960
            QVK +QDAIR KK+ F+FLGE I L P+VGIFITMNPGYAGR ELPENLK+LFRPCAMVV
Sbjct: 1938 QVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVV 1997

Query: 1961 PDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSL 2020
            PDFELICEIML+AEGF+EA+ LARKFITLY LCKELLSKQDHYDWGLRAIKSVLVVAGSL
Sbjct: 1998 PDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSL 2057

Query: 2021 KRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQ 2080
            KRGDP R EDQVLMR+LRDFNIPKIVTDD+P+FMGLIGDLFPALDVPR+RD NFE ++++
Sbjct: 2058 KRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRK 2117

Query: 2081 SIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVA 2140
            +IV+LKLQAED+FVLKVVQLEELL VRHSVF+VG AG+GKSQVL+SL+KTYQ +KR+PV 
Sbjct: 2118 AIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKRRPVW 2177

Query: 2141 VDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIES 2200
             DL+PKAVT DELFGIINP T EWKDGLFS+IMR+LANITHDGPKWI+LDGDIDPMWIES
Sbjct: 2178 TDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDGPKWILLDGDIDPMWIES 2237

Query: 2201 LNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPV 2260
            LNTVMDDNKVLTLASNERIPLN TM+L+FEISHLRTATPATVSRAGILYINPADLGWNP 
Sbjct: 2238 LNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPP 2297

Query: 2261 VSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLT 2320
            VSSWIE+R++Q+E+ANL ILFDKYLPTCLD LR  FKKI P+PE +++Q + +LLECLLT
Sbjct: 2298 VSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLT 2357

Query: 2321 EKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTI 2380
             + +P D P+E+YE YFVF   WAFGGAM QDQLVDYR EFSKWW+ EFKT+KFPSQGTI
Sbjct: 2358 TEDIPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSKWWLTEFKTVKFPSQGTI 2417

Query: 2381 FDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLV 2440
            FDYYIDP+TKKF PW+  VP FE DP++PLQA LVHT+ETIR+ YFM+ LM +  PVMLV
Sbjct: 2418 FDYYIDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLV 2477

Query: 2441 GNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGT 2500
            G AGTGKSVL+G KL SL+ + YLV+ VPFN+YTTSAMLQ VLEKPLEKK+GRNYGPPG 
Sbjct: 2478 GTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGN 2537

Query: 2501 KKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTS 2560
            KKL+YFIDDMNMPEVD YGTV PHT+IRQH+D+ HWYDR KL+LK+I N QYV+CMNPT+
Sbjct: 2538 KKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQYVSCMNPTA 2597

Query: 2561 GSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALA 2620
            GSFTI+ RLQRHF VF +SFPG +AL++IY+ ILTQHL   +   ++Q+    L+  ALA
Sbjct: 2598 GSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLALA 2657

Query: 2621 LHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGD 2680
             HQKI  TFLPT IKFHY+FNLRD +NIFQG+LFS+ E +K+  DL+RL+LHE+ RVY D
Sbjct: 2658 FHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRD 2717

Query: 2681 KMVDEKDQETLHRVTMASTKKFFDDLGDELLFAK-PNIFCHFAQGIGDPKYVPVTDMAPL 2739
            KMV+EKD +   ++     KK FDD+ D +   + PN++CHFA GIG+PKY+PV     L
Sbjct: 2718 KMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFANGIGEPKYMPVQSWELL 2777

Query: 2740 NKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRL 2799
             + LV+ L+++NEVN VM+LVLFEDA+ H+C INRILESPRGNALLVGVGGSGKQSL+RL
Sbjct: 2778 TQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQSLTRL 2837

Query: 2800 AAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLIN 2859
            AA+IS +DVFQITL+KGY I D K+DLA+  +KA VKN+ +VFLMTD+QVA+E+FLVLIN
Sbjct: 2838 AAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVLIN 2897

Query: 2860 DLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSP 2919
            DLLASGEIP L+ +DEVENIIS++R +VKS G+ D RE CWKFFI+++RRQLKV LCFSP
Sbjct: 2898 DLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKFFIDRIRRQLKVTLCFSP 2957

Query: 2920 VGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSY 2979
            VG+ LRVR+RKFPA+VNCTAI WFHEWP+ AL SVS RFL+ TEGI   VK SIS FM++
Sbjct: 2958 VGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQSISKFMAF 3017

Query: 2980 VHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQ 3039
            VHT+VN+ S+ YL+ E+RYNYTTPK+FLE I+LYQ+LL + R EL  K ERLENGL+KL 
Sbjct: 3018 VHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLH 3077

Query: 3040 STASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINK 3099
            ST++QVDDLKAKLA QE ELKQKNE AD+LIQVVG+E +KVS+EKA+AD+EE KV VI  
Sbjct: 3078 STSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIML 3137

Query: 3100 NVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTA 3159
             V +KQK CE DLAKAEPAL AAQ AL+TLNK NLTELKSFGSPP AV NV+AAVM+L A
Sbjct: 3138 EVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMA 3197

Query: 3160 PGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRS 3219
            P G++PKD+SWKAAK+ M KVD FLDSL  F+KE+I E CLKA +PY  +P F+PEF+ +
Sbjct: 3198 PRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDPEFNPEFVAT 3257

Query: 3220 KSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANL 3279
            KS AAAGLCSW INIVRFYEV+CDV PKRQAL +A A+L  AQEKL+ IK KIA LN NL
Sbjct: 3258 KSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENL 3317

Query: 3280 SNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLC 3339
            + LT+ FEKATA+K+KCQQEA+ T   I LANRLVGGLASEN+RWA++V+NF+ Q  TLC
Sbjct: 3318 AKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLC 3377

Query: 3340 GDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVAT 3399
            GD+LLI+AF+SY+G+FTKKYR  L+++ W PY+  LK PIP+T  LDPL +L DDADVA 
Sbjct: 3378 GDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPLRMLMDDADVAA 3437

Query: 3400 WNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDV 3459
            W N+GLP+DRMS ENATIL N ERWPL+VD QLQGIKWIKNKY  +L+  ++GQK YL +
Sbjct: 3438 WQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYGEDLRVTQIGQKGYLQI 3497

Query: 3460 IEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKY 3519
            IEQA+  G  +LIEN+ E++DPVL PLLGR  IKKG++IKIGDKE EY+PKFRLILHTK 
Sbjct: 3498 IEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGDKECEYNPKFRLILHTKL 3557

Query: 3520 FNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLK 3579
             NPHY+PE+QAQ TLINF VTRDGLEDQLLAAVV+ ERPDLEQLK++LTK QN FKI LK
Sbjct: 3558 ANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKITLK 3617

Query: 3580 ELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRP 3639
             LEDSLL+RLS+ASGNFLG+T LVENLE TK TA+E+E+KV EAK+TEVKINEARE+YRP
Sbjct: 3618 TLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAREHYRP 3677

Query: 3640 AAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYS 3699
            AA RASLLYFI+NDL+KI+P+YQFSLKAF++VF+KA++R  P   +++RV NL D IT+S
Sbjct: 3678 AAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFS 3737

Query: 3700 VYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQG 3759
            VY YT RGLFE DKL +LAQ+TFQ+L M +E+N VELDFLLR P + G  SPV+FL HQ 
Sbjct: 3738 VYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVEFLSHQA 3797

Query: 3760 WGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCL 3819
            WG +K LS M+EF NLD DIEGSAK WKK VESE PEKE  P+EWKNKTALQ+LCM+R +
Sbjct: 3798 WGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTALQRLCMLRAM 3857

Query: 3820 RPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALG 3879
            RPDRMTYA+++FVEEK+GSK+V GR+++F+ S+EES P+T +FFILSPGVDPLKDVE+ G
Sbjct: 3858 RPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQG 3917

Query: 3880 KKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLG 3939
            +KLG+T +N   HNVSLGQGQEVVAE ALD+AA+KGHWVILQ        NIHLVA+WL 
Sbjct: 3918 RKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQ--------NIHLVAKWLS 3969

Query: 3940 TLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKA 3999
            TL+KKLE +S  SH ++RVF+SAEPAPSPE HIIPQGILEN+IKITNEPPTGMHANLHKA
Sbjct: 3970 TLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKA 4029

Query: 4000 LDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINV 4059
            LD FTQDTLEMC++E EFK +LFALCYFHAVVAERRKFG QGWNRSYPFN GDLTIS+NV
Sbjct: 4030 LDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNV 4089

Query: 4060 LYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG 4119
            LYN+LEAN KVP+DDLRYLFGEIMYGGHITDDWDRRLCRTYL E+IR EMLEG++ LAPG
Sbjct: 4090 LYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPG 4149

Query: 4120 FQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDS 4179
            F +P N+DY GYH+YID  LPPESPYLYGLHPNAEIGFLT TSEKLFRTVLE+QP+++ +
Sbjct: 4150 FPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQA 4209

Query: 4180 GAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAE 4239
              G G +REEK                             VKA+L++ILE++ + FN+ E
Sbjct: 4210 RDGAGATREEK-----------------------------VKALLEEILERVTDEFNIPE 4240

Query: 4240 IMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYD 4299
            +MAK  E+TPY+VVAFQEC RMNILT E++RSL+EL LGLKGELT+T+ +E+L  AL++D
Sbjct: 4241 LMAKVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFD 4300

Query: 4300 TVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIM 4359
             VP++W  RAYPS  GLAAW+ DLL RI+ELEAWT DF +P+TVWL GFFNPQSFLTAIM
Sbjct: 4301 MVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIM 4360

Query: 4360 QSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARL 4419
            QS ARKNEWPLD+M L  ++TKKNRE+  +PPREG+Y++GLFMEGA WDTQ G+I EA+L
Sbjct: 4361 QSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKL 4420

Query: 4420 KELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAV 4479
            K+LTP MPV+FIKAIP D+ + +++Y CPVYKT  RGPTYVWTFNLKTKE  +KW+LA V
Sbjct: 4421 KDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPTYVWTFNLKTKENPSKWVLAGV 4480

Query: 4480 ALLLQV 4485
            ALLLQ+
Sbjct: 4481 ALLLQI 4486


>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
          Length = 4523

 Score = 5294 bits (13732), Expect = 0.0
 Identities = 2620/4516 (58%), Positives = 3367/4516 (74%), Gaps = 78/4516 (1%)

Query: 2    TMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAGM 61
            + A D R+ +L    +++L F  +KWS+ + +E+N  +  EF E      LV +  A+G 
Sbjct: 52   SFAQDARVRFLGGRLAMMLGFTEEKWSQYLESEDNRQVLGEFLESTSPACLVFSFAASGR 111

Query: 62   IIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSLL 121
            +      P+    K V+  K  +E+I  +++   +L+G++    +  + A ++E+L  +L
Sbjct: 112  LAASQEIPRDANHKLVFISKKITESIGVNDFSQVVLFGELPALSLGHVSAFLDEILVPVL 171

Query: 122  NQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMERI 181
            +   N   W    S+D+   +  +K +M++  GK+  +TLLPIP   G +D      E  
Sbjct: 172  SNKNNHKSWSCFTSQDMEYHIEVMKKKMYIFRGKMSRRTLLPIPTVAGKMDLDQNCSENK 231

Query: 182  PSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCI 241
            P S + ++LHAIE+ +I+WSHQI++++ +DS Q LL+GLH  PQ E +FW  R  NL CI
Sbjct: 232  PPSNERIILHAIESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQAELDFWMMRRENLSCI 291

Query: 242  HEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQ 301
            ++QL  P V K+V+IL   +S Y+P L++++  V   L EA D+ LYL+PLR  ++ +++
Sbjct: 292  YDQLQAPVVLKMVKILTTKQSSYFPTLKDIFLAVENALLEAQDVELYLRPLRRHIQCLQE 351

Query: 302  ADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLKG 361
             +F      IA +  TIC IW+ S++YNTPAR+IV+LQEFCN  I     +LSPE++L+G
Sbjct: 352  TEFPQTRILIAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFINQATAYLSPEDLLRG 411

Query: 362  LQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFF 421
               EIEE L  + +AVN+LK    ++      +  +F  ++  PW+F S L F R + F 
Sbjct: 412  ---EIEESLEKVQVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDFQSHLVFCRFDKFL 468

Query: 422  QRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLDP 481
             R+  IE+++ T +EF KLE++E GG +G +L   V  + +E+ EL K+F    YDP D 
Sbjct: 469  DRLIKIEDIFATTLEFEKLERLEFGGTKGAILNGQVHEMSEELMELCKLFKQSTYDPSDC 528

Query: 482  GDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAEV 541
             +  F+ DY  F+ K  + DRRL TI C+ F +C+ ++++ KLL + G  +E+P+++   
Sbjct: 529  TNMEFESDYVAFKSKTLEFDRRLGTIICEAFFNCNGLEAAFKLLTIFGNFLEKPVVMEIF 588

Query: 542  APRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLEV 601
            +  YS ++ +F+ ELD  K LY+  M   E G++ +++KNMP  +G +KW+ ++ +RL++
Sbjct: 589  SLHYSTLVHMFNTELDVCKQLYNEHMKQIECGHV-VLNKNMPFTSGNMKWAQQVLQRLQM 647

Query: 602  SMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPLI 661
               +   + +  +   +  L YQKY EM  LL     +IY +W + VD+ C FNL QPL+
Sbjct: 648  FWSNFASLRYLFLGNPDHALVYQKYVEMTTLLDQFESRIYNEWKSNVDEICEFNLNQPLV 707

Query: 662  LRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELIV 721
               A + L+ VNF   LVAVLREVKYL   ++++IPDSA ++F +  T  K++GNL+L+V
Sbjct: 708  KFSAINGLLCVNFDPKLVAVLREVKYLLMLKKQDIPDSALAIFKKRNTILKYIGNLDLLV 767

Query: 722  GWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQNR 781
              YN++K  +  VE+ LI+ EL AID +L +A T L W  +  + YI+ VR     L++R
Sbjct: 768  QGYNKLKQTLLEVEYPLIEDELRAIDEQLTAATTWLTWQDD-CWGYIERVRAATSELEHR 826

Query: 782  MQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQA 841
            +++ ++N++ I Q M+ W+   L  R+++++EA   L+ +     K+Y  ++  G KI  
Sbjct: 827  VERTQKNVKVIQQTMRGWARCVLPPRREHRREAAFTLEDKGDLFTKKYKLIQGDGCKIHN 886

Query: 842  MVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFEI 901
            +V EN +LF+A+     WK YV +IDD+V++ F Q I   L F + N       AP F+ 
Sbjct: 887  LVEENRKLFKANPSLDTWKIYVEFIDDIVVEGFFQAIMHDLDFFLKNTEKQLKPAPFFQA 946

Query: 902  RMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAK--DRMNYKMDLEDN 959
            +M L    + F P+L+  +  GF  L+E ++ + + ++  + R+A   +  NY+ D+++ 
Sbjct: 947  QMILLPPEIVFKPSLDREAGDGFYDLVEEMLCNSFRMSAQMNRIATHLEIKNYQNDMDNM 1006

Query: 960  TDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDT 1019
              L E+R+E+ + V+N + +  +++++ E ++YLW D+  EFMK+FL+YG AV+++++D 
Sbjct: 1007 LGLAEVRQEIMNRVVNVINKVLDFRNTLETHTYLWVDDRAEFMKHFLLYGHAVSSDEMDA 1066

Query: 1020 WTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRR 1079
              ++ IP+ PPTL QF+EQID YE LY ++SK E+ +VF  W + D +PFK +LL+ I++
Sbjct: 1067 HANEEIPEQPPTLEQFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLLTIIKK 1126

Query: 1080 WGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAAT 1139
            W +MF+ HL   V +SL +L+ F+K    GL + L EGD+DGLV++M HL+ V+ RQ AT
Sbjct: 1127 WSWMFQEHLLRFVIDSLNELQEFIKETDSGLQRELNEGDHDGLVDIMVHLLAVRSRQRAT 1186

Query: 1140 DNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSI 1199
            D +FEPLK+TI LL++YG++MPE+++++L+ELPE W  TKK+A  V+  V+PL   EV++
Sbjct: 1187 DELFEPLKETITLLESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEVTL 1246

Query: 1200 LRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNK----VFLLKGIMEALSKSGGLF 1255
            +R+KC  F+ KQ EFRERFR  AP  F+  NPY +L+K    +  L+  M  + +S  LF
Sbjct: 1247 IRKKCILFDAKQAEFRERFRHYAPLGFNAENPYTALDKANEELEALEEEMLQMQESTRLF 1306

Query: 1256 EVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAK- 1314
            EV +P+YKQ+K C +E++LLK LWD+++ V  SI++W  T+W+ I+VEQMD++ ++FAK 
Sbjct: 1307 EVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRRFAKA 1366

Query: 1315 ----DMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKF 1370
                ++ SL+KE++ WDA+ GL+ TVK++  SLRA++ELQ+PA+R+RHW QLM+A  VKF
Sbjct: 1367 SSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQSPALRDRHWHQLMKAIGVKF 1426

Query: 1371 KMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRT 1430
             ++E TTLADLL L LH  ED+VR IVDKAVKE G EKV+  +  TW+ M+F +E H RT
Sbjct: 1427 LINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTWATMKFSYEVHYRT 1486

Query: 1431 GTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQR 1490
            G  +LKS E L ETLE NQVQLQ L+ SKY+ +F+++V SWQ KL+ AD VI  W EVQR
Sbjct: 1487 GIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQR 1546

Query: 1491 TWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLE 1550
            TWSHLESIF+ SEDIR QL  D++RFD ++ EFK LM    K  NV+EAT +P LY KL+
Sbjct: 1547 TWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVENVLEATCRPNLYEKLK 1606

Query: 1551 ALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLC 1610
             L+  L++CEKALAEYLETKR+AFPRFYFVSSADLLDILS G  P +V+ HL+KLFDS+ 
Sbjct: 1607 DLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQPKQVTCHLAKLFDSIA 1666

Query: 1611 KLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPE 1670
             L+F  D  D      +GMYSKE EY+ F  EC+  G VE WL ++   M  T+RH I E
Sbjct: 1667 DLQFE-DNQDVSAHRAVGMYSKEKEYVPFQAECECVGHVETWLLQLEQTMQETVRHSITE 1725

Query: 1671 AVVTYEEKPREQWILDYPAQ-------IWWTTEVGLAFARLEEGYENAIKDYNKKQISQL 1723
            A+V YEEKPRE WI D+PAQ       IWWTT+VG+AF+RLEEGYE A+KD++KKQISQL
Sbjct: 1726 AIVAYEEKPRELWIFDFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQL 1785

Query: 1724 NVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI-----VESSQAFTWQAQLRHRWD 1778
            N LITLL+G L  GDR KIMTICTIDVHARDVVAK+I     V S QAFTW +QLRHRW+
Sbjct: 1786 NTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWE 1845

Query: 1779 EEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTG 1838
            + ++HCF NICDAQ QY YEYLGN+PRLVITPLTDRCYITLTQSLHL M GAPAGPAGTG
Sbjct: 1846 DTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTG 1905

Query: 1839 KTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVI 1898
            KTETTKDLGRALG MVYVFNCSEQMDYKS GNIYKGL QTGAWGCFDEFNRISVEVLSV+
Sbjct: 1906 KTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVV 1965

Query: 1899 AVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAM 1958
            AVQVK + DAIR +KK F FLGE I L P+VGIFITMNPGYAGR ELPENLKALFRPCAM
Sbjct: 1966 AVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAM 2025

Query: 1959 VVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAG 2018
            V PD ELICEI+L+AEGF++AR LARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAG
Sbjct: 2026 VAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAG 2085

Query: 2019 SLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKII 2078
            SLKRGD +R EDQVLMRALRDFN+PKIVTDD+PVF+GL+GDLFPALDVPR+R L+FE+++
Sbjct: 2086 SLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMV 2145

Query: 2079 KQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKP 2138
            +QS +EL+LQ E+SF+LKVVQLEELL VRHSVF+VGNAG+GKS++L++LN+TY N+K+KP
Sbjct: 2146 RQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKP 2205

Query: 2139 VAVDLDPKAVTCDELFGIINPVTREWKDG---------LFSTIMRDLANITHDGPKWIIL 2189
            V  DL+PKAVT DELFG I+  TREWKDG         LFS+I+R+ AN+ HDGPKWI+L
Sbjct: 2206 VWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVL 2265

Query: 2190 DGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILY 2249
            DGDIDPMWIESLNTVMDDNKVLTLASNERI L   MRL+FEI HLR+ATPATVSRAGILY
Sbjct: 2266 DGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILY 2325

Query: 2250 INPADLGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQ 2309
            +NP DLGWNP V+SWI+RR+ QSEKANL ILFDKY+P CLDKLR  FK IT +PE +++Q
Sbjct: 2326 VNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQ 2385

Query: 2310 TILYLLECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEF 2369
            T+  LLECLLT + VP DSP+E+YE+YFVF C WAFGG + QDQ+ DY+ +FS+WW  E 
Sbjct: 2386 TLCVLLECLLTPENVPSDSPKEVYEVYFVFACIWAFGGTLLQDQISDYQADFSRWWQKEM 2445

Query: 2370 KTIKFPSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDL 2429
            K +KFPSQGTIFDYY+D  TKK LPW DK+  F +DPDVPLQ  LVHTTET R+RYFM+L
Sbjct: 2446 KAVKFPSQGTIFDYYVDHKTKKLLPWADKIAQFTMDPDVPLQTVLVHTTETARLRYFMEL 2505

Query: 2430 LMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEK 2489
            L+EK  P+MLVGNAG GK+V +GD L SL+ D Y+V  VPFN+YTTS  LQ +LEKPLEK
Sbjct: 2506 LLEKGKPLMLVGNAGVGKTVFVGDTLASLSED-YIVSRVPFNYYTTSTALQKILEKPLEK 2564

Query: 2490 KSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHN 2549
            K+G NYGP G KKL+YFIDDMNMPEVD YGTV PHTLIRQH+D+ HWYDR K+ LK+IHN
Sbjct: 2565 KAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEIHN 2624

Query: 2550 CQYVACMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQR 2609
            CQYVACMNP  GSFTI+ RLQRHF VFA +FP  +AL TIY  I + H   ++ + +I R
Sbjct: 2625 CQYVACMNPMVGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILR 2684

Query: 2610 ISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRL 2669
                L+ A +A HQ +   FLPTAIKFHY+FNLRDLSN+FQG+LF++ E LK PLDL+ L
Sbjct: 2685 SGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHL 2744

Query: 2670 WLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPK 2729
            WLHE+ RVYGDK++D+KD +   R  + +  K+F+ +   +L  +P I+CHFA    DP 
Sbjct: 2745 WLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHMLLQQPLIYCHFADRGKDPH 2804

Query: 2730 YVPVTDMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVG 2789
            Y+PV D   L  +L + LD+YNE+NA M+LVLFEDA+ H+CRI+RIL +P+G ALLVGVG
Sbjct: 2805 YMPVKDWEVLKTILTETLDNYNELNAAMHLVLFEDAMQHVCRISRILRTPQGCALLVGVG 2864

Query: 2790 GSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQV 2849
            GSGKQSLSRLAAY+ GL+VFQITL +GYGI +L++DLA  YI+   KN+P+VFL+TD+QV
Sbjct: 2865 GSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAKNMPTVFLLTDAQV 2924

Query: 2850 AEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRR 2909
             +E FLVLINDLLASGEIP LF +++V+ IIS +  +V +LGM D+RE CWKFF+ +VR 
Sbjct: 2925 LDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHALGMVDSRENCWKFFMARVRL 2984

Query: 2910 QLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEV 2969
            QLK+ILCFSPVG  LRVRARKFPA+VNCTAIDWFH WP++ALVSVS RF+EET+GI    
Sbjct: 2985 QLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVSRRFIEETKGIEPVH 3044

Query: 2970 KASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIE 3029
            K SIS FM++VHTTVNEMS  Y   ERR+NYTTPK+FLEQI L++NLL KK+ E+  K E
Sbjct: 3045 KDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKE 3104

Query: 3030 RLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQ 3089
            RL NG+ KL++TASQV DLKA+LA QEAEL+ +N  A+ LI  +G++ EKVS+EK IAD 
Sbjct: 3105 RLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSREKTIADA 3164

Query: 3090 EEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVN 3149
            EE KV  I   V +KQ+ CE DL KAEPAL+AA  AL+TLN+ NL+ELK+F +PP AV N
Sbjct: 3165 EERKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTN 3224

Query: 3150 VTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKP-YQG 3208
            VTAAVM+L AP G++PKD+SWKAAK+ MGKVD FL +L  +DKEHIPE CLK     Y  
Sbjct: 3225 VTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLK 3284

Query: 3209 NPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRI 3268
            +P F+P  IR+KS AAAGLC+W INI++FYEVYCDV PKRQAL +AN ELA A EKL  I
Sbjct: 3285 DPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAI 3344

Query: 3269 KNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESV 3328
            + K+ +L+ NLS LT++FEKATAEK++CQ+E + TN+ I LANRLV  L ++ IRW +S+
Sbjct: 3345 RKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSI 3404

Query: 3329 ENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPL 3388
            ++F +Q  TLCGDVLL +AFVSYVG FT++YR EL+   W+P++   KV IP+T GLD +
Sbjct: 3405 KSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWVPFLQQ-KVSIPLTEGLDLI 3463

Query: 3389 SLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKA 3448
            S+LTDDA +A WNN+GLPSDRMSTENA IL + ERWPL++D Q QGIKWIKNKY  +LK 
Sbjct: 3464 SMLTDDATIAAWNNEGLPSDRMSTENAAILTHCERWPLVIDPQQQGIKWIKNKYGMDLKV 3523

Query: 3449 IRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYH 3508
              LGQK +L+ IE A++ GD +LIEN+ ET+DPVLDPLLGRNTIKKGKYI+IGDKE E++
Sbjct: 3524 THLGQKGFLNAIETALAFGDVILIENLEETIDPVLDPLLGRNTIKKGKYIRIGDKECEFN 3583

Query: 3509 PKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLT 3568
              FRLILHTK  NPHYKPE+QAQ TL+NF VT DGLE QLLA VV+ ERPDLE+LK  LT
Sbjct: 3584 KNFRLILHTKLANPHYKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLT 3643

Query: 3569 KSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEV 3628
            K QN+FKI LK LED LL RLSAA G+FL DT LVE LE TK T +EIE KV+EAK  E 
Sbjct: 3644 KHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENER 3703

Query: 3629 KINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQR 3688
            KINEARE YRP A RASLLYF++NDL KINP+YQFSLKAFNV+F +AI++     +++ R
Sbjct: 3704 KINEARECYRPVAARASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGR 3763

Query: 3689 VINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGV 3748
            +  L + IT++V++YT++ LFE+DKL FL+Q+ FQ+L  KKE++P+ELDFLLRF  +   
Sbjct: 3764 ISILMESITHAVFLYTSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLRFTVEHTH 3823

Query: 3749 VSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKT 3808
            +SPVDFL  Q W  IKA++ M+EF+ +D D+EGSAK+W+K VESE PEKE  P+EWK K+
Sbjct: 3824 LSPVDFLTSQSWSAIKAIAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKS 3883

Query: 3809 ALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPG 3868
             +QKL ++R +RPDRMTYA++NFVEEK+G+K+VE   ++  K++EESSP+T IFFILSPG
Sbjct: 3884 LIQKLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPG 3943

Query: 3869 VDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHC 3928
            VD LKD+E LGK+LGFTID+GK HNVSLGQGQE VAE AL+ A++ GHWVILQ       
Sbjct: 3944 VDALKDLEILGKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQ------- 3996

Query: 3929 RNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEP 3988
             N+HLVA+WLGTL+K LER+S GSH DYRVF+SAE AP+P+ HIIPQG+LEN+IKITNEP
Sbjct: 3997 -NVHLVAKWLGTLEKLLERFSQGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEP 4055

Query: 3989 PTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPF 4048
            PTGM ANLH AL  F QDTLE+C+KE EFK +LF+LCYFHA VA R +FG QGW+RSYPF
Sbjct: 4056 PTGMLANLHAALYNFDQDTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPF 4115

Query: 4049 NNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTE 4108
            N GDLTI  +VLYNYLEAN KVPW+DLRYLFGEIMYGGHITDDWDR+LCR YL E++   
Sbjct: 4116 NPGDLTICASVLYNYLEANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPS 4175

Query: 4109 MLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRT 4168
            + E +++LAPGF  PP LDY GYH+YI+E LPPESP LYGLHPNAEI FLTVTS  LFRT
Sbjct: 4176 LTEDELMLAPGFAAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRT 4235

Query: 4169 VLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDIL 4228
            +LEMQP+   SG   G S EEK                             VK VLDDIL
Sbjct: 4236 LLEMQPRNALSGDELGQSTEEK-----------------------------VKNVLDDIL 4266

Query: 4229 EKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTD 4288
            EK+PE FNMAEIM K + ++PYV+V FQECERMNIL  E+R SL++L+L LKGEL ++  
Sbjct: 4267 EKLPEEFNMAEIMQKNSNRSPYVLVCFQECERMNILIREIRISLEQLDLSLKGELALSPA 4326

Query: 4289 VEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGF 4348
            VE    AL YDTVPDTW   AYPS  GLA W+ DLLLR REL+ WT D  LP  VWL+GF
Sbjct: 4327 VEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAVVWLSGF 4386

Query: 4349 FNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWD 4408
            FNPQSFLTAIMQ+MARKNEWPLDK  L+ +VTKK +ED   PPREG+Y++GLFMEGARWD
Sbjct: 4387 FNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGAYLHGLFMEGARWD 4446

Query: 4409 TQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTK 4468
            TQ G I EARLKEL   MPVIF KA PVDR ETK  YECPVY+T++RGP+Y+WTF LK++
Sbjct: 4447 TQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTKLRGPSYIWTFRLKSE 4506

Query: 4469 EKAAKWILAAVALLLQ 4484
            EK AKW+LA VALLL+
Sbjct: 4507 EKTAKWVLAGVALLLE 4522


>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
          Length = 4471

 Score = 2287 bits (5927), Expect = 0.0
 Identities = 1445/4480 (32%), Positives = 2366/4480 (52%), Gaps = 333/4480 (7%)

Query: 132  QVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMERIPSSLDNLLLH 191
            Q++ ++ +  V +  + +     +++G+  L +P  + S++G +  +   P ++D L   
Sbjct: 194  QLIRDEFLMNVQKFASNIQRTMQQLEGEIKLEMP--IISVEGEVSDLAADPETVDIL--- 248

Query: 192  AIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQLNRPKVN 251
              E  +I+W +QI   +    AQ         P  E EFW  R   L  +HEQ   P V 
Sbjct: 249  --EQCVINWLNQISTAVE---AQLKKTPQGKGPLAEIEFWRERNATLSALHEQTKLPIVR 303

Query: 252  KIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQAD-FTMLPTF 310
            K++++++++ S     LQ V+T + +   EA+D V +L  +    + +     F ++   
Sbjct: 304  KVLDVIKESDSMLVANLQPVFTELFKFHTEASDNVRFLSTVERYFKNITHGSGFHVVLDT 363

Query: 311  IAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLKGLQGEIEEVL 370
            I  ++  +  +W  S +YN   R+I +++    +I E     ++   + K  +   +   
Sbjct: 364  IPAMMSALRMVWIISRHYNKDERMIPLMERIAWEIAERVCRVVNLRTLFKENRASAQSKT 423

Query: 371  SGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFFQRIQTIEEL 430
                  + + K+ Y  +D      K+    +E   WEF     F R +      Q + ++
Sbjct: 424  LEARNTLRLWKKAY--FD---TRAKIEASGRED-RWEFDRKRLFERTDYMATICQDLSDV 477

Query: 431  YKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLDPGDSNFDRDY 490
             +   EF  +   EL  V G+       +  D+V         C+ D L     N     
Sbjct: 478  LQILEEFYNIFGPELKAVTGD------PKRIDDVL--------CRVDGLVTPMENLT--- 520

Query: 491  ADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAEVAPRYSVMLE 550
                                 FD  S IKSS    Y+        LI         ++ +
Sbjct: 521  ---------------------FDPFS-IKSSQFWKYVMDEFKIEVLI--------DIINK 550

Query: 551  LFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLEVSMKHLKHVE 610
            +F   L+N                 P ++KN PPVAG + W   L  R++ ++   + V+
Sbjct: 551  IFVQNLEN-----------------PPLYKNHPPVAGAIYWERSLFFRIKHTILRFQEVQ 593

Query: 611  HPVMS--GAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPLILRDAASN 668
              + S  G E K   QKY E+   ++ + ++ Y+QW+   +Q     + + L+ + + + 
Sbjct: 594  EILDSDRGQEVK---QKYLEVGRTMKEYEDRKYEQWMEVTEQVLPALMKKSLLTKSSIAT 650

Query: 669  ----------LIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLE 718
                      +  +NFS AL  ++ E KYL  Q    +P+ A ++  + + F ++   ++
Sbjct: 651  EEPSTLERGAVFAINFSPALREIINETKYLE-QLGFTVPELARNVALQEDKFLRYTAGIQ 709

Query: 719  LIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNL 778
             ++  Y+ +   +   E +L+K   + +     S    L WN  G+  YI   ++ +   
Sbjct: 710  RMLDHYHMLIGTLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIGDYITGCKQAIGKF 769

Query: 779  QNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALL------------DLDGRIANLN 826
            ++ + +  +N + IS  +    A  LF+    K E  L            +    + ++ 
Sbjct: 770  ESLVHQIHKNADDISSRLTLIEAINLFKYPAAKSEEELPGVKEFFEHIERERASDVDHMV 829

Query: 827  KRYAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLM 886
            + Y A+     K++ +V  +    +A  L+     Y  Y +  + +   + I K+L    
Sbjct: 830  RWYLAIGPLLTKVEGLVV-HTNTGKAPKLA----SYYKYWEKKIYEVLTKLILKNLQSF- 883

Query: 887  DNMVIDESIAPLFEIRMELDEDGLTFNP-TLEVGSDRGFLALIEGLVNDIYNVARLI--- 942
             N +I  ++ PLF     L    +  +P T E+  D+     +   V    +  R +   
Sbjct: 884  -NSLILGNV-PLFHTETILTAPEIILHPNTNEI--DKMCFHCVRNCVEITKHFVRWMNGS 939

Query: 943  -----PRLAKDR----MNYKMDLEDNTDLIEMR----EEVSSLVINAMKEAEEYQDSFER 989
                 P+  ++     +N+  D+  N  +IE      + V  ++IN MK    Y   ++R
Sbjct: 940  CIECPPQKGEEEEVVIINFYNDISLNPQIIEQAVMIPQNVHRILINLMK----YLQKWKR 995

Query: 990  YSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEV 1049
            Y  LW  +    M+ F                     K PP +A + E++  Y K+  EV
Sbjct: 996  YRPLWKLDKAIVMEKFAA-------------------KKPPCVA-YDEKLQFYSKIAYEV 1035

Query: 1050 SKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMG 1109
             +    K  H  ++   R     +    + W     + L+      L +L   M+     
Sbjct: 1036 MRHPLIKDEH-CIRLQLRHLANTVQENAKSWVISLGKLLNESAKEELYNLHEEMEHLAKN 1094

Query: 1110 LTKPLKEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQ 1169
            L K       + L  V+  + +++ +    +  +  +++    +  Y    P+     + 
Sbjct: 1095 LRKI--PNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYNLFPPDAEKELVD 1152

Query: 1170 ELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDP 1229
            ++   W+N    ++ V+  +  ++     + R +   + ++  EF +RF  E P S  D 
Sbjct: 1153 KIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKRFYSEGPGSVGD- 1211

Query: 1230 NPYKSLNKVFLLKGIMEA-----------LSKSGGLFEVPVPDYKQLKACHREVRLLKEL 1278
                 L+K   L G+ E            L+ +  LF++P+  Y +L    +E+  L+ +
Sbjct: 1212 ----DLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKEMSGLRMI 1267

Query: 1279 WDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKN 1338
            +++   +  + E+W  T W ++NV+ +    + F + +R L + ++       L+  +K 
Sbjct: 1268 YELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKMKA 1327

Query: 1339 VITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVD 1398
               S+  + +L+N A+R+RHW++LM+ T V F+M+E  TL ++  + LH + D +  IV 
Sbjct: 1328 FKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTDVLNEIVT 1387

Query: 1399 KAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTM----MLKSSEVLVETLEDNQVQLQN 1454
             A+KE  +EK +K +  TW  M+F    + + GT     +L S + ++++L+DN   LQ+
Sbjct: 1388 AAIKEVAIEKAVKEILDTWENMKFTVVKYCK-GTQERGYILGSVDEIIQSLDDNTFNLQS 1446

Query: 1455 LMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQ 1514
            +  S+++  FL+ V  W++ LS    VI IW  VQR W +LESIFIG  DIR+QLP +++
Sbjct: 1447 ISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGG-DIRSQLPEEAK 1505

Query: 1515 RFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAF 1574
            +FD+I++ FK +M + +K P +      P   + L+ + + L  C+K+L +YL++KR AF
Sbjct: 1506 KFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAF 1565

Query: 1575 PRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKED 1634
            PRF+F+S  +LL IL + +DP+ V  H+ K++D++  L+F  +  D   K+   M S E 
Sbjct: 1566 PRFFFISDDELLSILGS-SDPLCVQEHMIKMYDNIASLRF--NDGDSGEKLVSAMISAEG 1622

Query: 1635 EYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTY-EEKPREQWILDYP----- 1688
            E M F +     G+VE W+  VL+ M  T R    EA+  Y E++ R  W+L Y      
Sbjct: 1623 EVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWMLLYQGMVVL 1682

Query: 1689 --AQIWWTTEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRMKIMTIC 1746
              +Q+WWT EV   F + ++G + A+K+Y +K   Q++ L+T +   L+  DR K  T+ 
Sbjct: 1683 AASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVL 1742

Query: 1747 TIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNT 1803
             IDVHARD+V   I   +  ++ F W++QLR  WD E        C     Y YEY+G  
Sbjct: 1743 IIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLN 1802

Query: 1804 PRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQM 1863
             RLVITPLTDR Y+TLTQ+L + +GGAPAGPAGTGKTETTKDL +ALG +  V NC E M
Sbjct: 1803 GRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGM 1862

Query: 1864 DYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEII 1923
            DY++ G I+ GLAQ GAWGCFDEFNRI   VLSVI+ Q++ +++A+  +   F F G+ I
Sbjct: 1863 DYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQEI 1922

Query: 1924 GLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLA 1983
             L   +GIFITMNPGYAGR ELPE++KALFRP  ++VPD + ICEIML +EGFLEA+ LA
Sbjct: 1923 SLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLA 1982

Query: 1984 RKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIP 2043
            +K   LY L +E LSKQ HYD+GLRA+KSVLV+AG LKRG     ED VLMRALRD N+P
Sbjct: 1983 KKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLP 2042

Query: 2044 KIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEEL 2103
            K V +D+P+F+GLI DLFP LD PR R  +F   ++Q + E         V KVVQ+ E 
Sbjct: 2043 KFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFET 2102

Query: 2104 LQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTRE 2163
            +  RH+  +VG    GKS V+ +L +    L        L+PKAV+  EL+GI++P TR+
Sbjct: 2103 MLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYGILDPTTRD 2162

Query: 2164 WKDGLFSTIMRDLANITHDGP-KWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLN 2222
            W DG+ S I R++   T     K+I+ DGD+D +W+E++N+VMDDN++LTLA+ ERI L 
Sbjct: 2163 WTDGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQ 2222

Query: 2223 RTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFD 2282
                L+FE+  L+ A+PATVSR G++Y++P +L + P    W+ +   + E+ NL  LF+
Sbjct: 2223 AHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFE 2282

Query: 2283 KYLPTCLDKLRFG---------FKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRELY 2333
            KY+P  +D +  G          K I P  ++ ++  +  +L+ LL  +    D    L 
Sbjct: 2283 KYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEGEIEDLD----LL 2338

Query: 2334 ELYFVFTCFWAFGGAMFQDQLVDY-----------RVEFSKWWINEFKTIKFPSQ-GTIF 2381
            E YF+   + + G ++ +D  + +            V+    W N     + P Q  T++
Sbjct: 2339 ECYFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPG---ELPGQLPTLY 2395

Query: 2382 DYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVG 2441
            D++ D    +++PW+  VP +   P+      LVHT +T R  + ++ +++   PV+ VG
Sbjct: 2396 DFHFDNKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVG 2455

Query: 2442 NAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTK 2501
             +GT K+    + L++L+ +  +V  V F+  TTS  +Q  LE  +EK++   YGPP  K
Sbjct: 2456 ESGTSKTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGK 2515

Query: 2502 KLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHK-LTLKDIHNCQYVACMNPTS 2560
            +L+ F+DDMNMP VD+YGT  P  L++  ++  + YDR K L  K I +  ++A M    
Sbjct: 2516 RLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAG 2575

Query: 2561 GSFT-IDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAAL 2619
            G    +D R    F VF V FP +E+L  IY++IL  H +  +   +I  +S +L    L
Sbjct: 2576 GGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTS--TFHESIVAVSGKLTFCTL 2633

Query: 2620 ALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYG 2679
            AL++ I     PT  KFHY+FNLRDLS +F GL+ +  E  +T   +VR+W +E  RV+ 
Sbjct: 2634 ALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFH 2693

Query: 2680 DKMVDEKDQETLHR-VTMASTKKFFDDLGDELLFAKPNIFCHFAQGI--GDPK-YVPVTD 2735
            D+++ E D++ + + +     + F DD+  E++   P +F  F   +  G+P+ Y  + D
Sbjct: 2694 DRLISETDKQLVQQHIGSLVVEHFKDDV--EVVMRDPILFGDFQMALHEGEPRIYEDIQD 2751

Query: 2736 MAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQS 2795
                  L  ++L+ YNE N  MNLVLF+DA+ H+ R++RI+   RG+ALLVGVGGSGKQS
Sbjct: 2752 YEAAKALFQEILEEYNESNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQS 2811

Query: 2796 LSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFL 2855
            LSRLAA+ +  +VF+I L +GY     + DL + Y+K  ++N   +FL TD+ VAEE FL
Sbjct: 2812 LSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFL 2871

Query: 2856 VLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVIL 2915
             LIN++L SG +P LF E+E E+I+S +  +    GM   +E+ W++F+ K    L ++L
Sbjct: 2872 ELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKSANNLHIVL 2931

Query: 2916 CFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISF 2975
              SPVG  LR   R FP +VN T IDWF  WP  AL +V+  FL     IP E   ++  
Sbjct: 2932 GMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVK 2991

Query: 2976 FMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGL 3035
             +  VH +V+  S+ +L   RR NY TPK +L+ I  Y  LL +K    +A+ +RL+ GL
Sbjct: 2992 HVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGL 3051

Query: 3036 MKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVE 3095
             KL+    Q+D+L  KLA Q+  L +K+ + + L++ + +      ++K +A+++ +++E
Sbjct: 3052 DKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIE 3111

Query: 3096 VINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVM 3155
              NK +  ++   ET LA+  P L AA+  L  L+K+++TE++SF  PP  V  V   ++
Sbjct: 3112 EQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECIL 3171

Query: 3156 ILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPE 3215
            I+     K  K+ +WK AK +M     FL SL + D + I ++ +K  K          E
Sbjct: 3172 IM-----KGYKELNWKTAKGVMSD-PNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTE 3225

Query: 3216 FIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAEL 3275
             + + S A  G+  +   ++ + +V+ ++ PKR+ +          + +L RI+N++A +
Sbjct: 3226 EMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAI 3285

Query: 3276 NANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQG 3335
               L  L + +E A  EK K Q+EA+   R ++ A++L+ GL SENIRW   ++    + 
Sbjct: 3286 QKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRR 3345

Query: 3336 VTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDA 3395
            V L GD LL +AF+SY G FT ++R+E++ + W   I  L+  IP++      SLLTDD 
Sbjct: 3346 VKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDI--LEREIPLSQPFRLESLLTDDV 3403

Query: 3396 DVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNK-YRSELKAIRLGQK 3454
            +++ W +QGLP D +S +N  +     R+PL +D Q Q + WIK K  ++ L+       
Sbjct: 3404 EISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDP 3463

Query: 3455 SYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRN-TIKKGK-YIKIGDKEVEYHPKFR 3512
             +L  +E +I  G   L  ++ E +DPV+D +L +N  + +G+ +I +GDKEV+Y   FR
Sbjct: 3464 DFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFR 3523

Query: 3513 LILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQN 3572
            L L+TK  NP Y P +  +  +IN+ VT  GLEDQLL+ +VA ER +LE+ + +L +  +
Sbjct: 3524 LYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETS 3583

Query: 3573 EFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINE 3632
            E K +LK+LEDSLL  L+ ++GN L +  LV  LE TK  A+E+ EK+  A+ T + I+ 
Sbjct: 3584 ENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDR 3643

Query: 3633 ARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINL 3692
             R+ YRPAA R ++L+F+L+++  +N +YQ+SL AF  VF  +++++ P + + +R+ N+
Sbjct: 3644 LRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNI 3703

Query: 3693 TDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPF---KAGVV 3749
             D +T+S+Y +   GLFER KL+F   +T ++   +  +   ELDF L+      K+   
Sbjct: 3704 MDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKSKRK 3763

Query: 3750 SPVDFLQHQGWGGIKALSEM--DEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNK 3807
             P  +L  QGW  I  LSEM  D F  L  D+E +   W++  + ++ E+   P  + N 
Sbjct: 3764 KPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQFPVPLGYDNN 3823

Query: 3808 -TALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILS 3866
             T  QKL ++RC R DR+  A+ ++V   MG K+V+   + F   +E+S+P + I FILS
Sbjct: 3824 ITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPHSPIVFILS 3883

Query: 3867 PGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQ 3926
            PG DP  D+  L ++ GF     +L  +++GQGQE VA   L+ A  +G W++LQ     
Sbjct: 3884 PGSDPATDLMKLAERSGF--GGNRLKFLAMGQGQEKVALQLLETAVARGQWLMLQ----- 3936

Query: 3927 HCRNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITN 3986
               N HL+ +WL  L+K LER  T  H D+R++++ +P     T   P GIL+ ++K+  
Sbjct: 3937 ---NCHLLVKWLKDLEKSLERI-TKPHPDFRLWLTTDP-----TKGFPIGILQKSLKVVT 3987

Query: 3987 EPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSY 4046
            EPP G+  N+       + + L+ C     FK +++ L +FHAVV ERRKFG  GWN  Y
Sbjct: 3988 EPPNGLKLNMRATYFKISHEMLDQC-PHPAFKPLVYVLAFFHAVVQERRKFGKIGWNVYY 4046

Query: 4047 PFNNGDLTISINVLYNYL-----EANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYL 4101
             FN  D  + + +L  YL     + +P++PW  L+YL GE+MYGG   D +DRR+   Y+
Sbjct: 4047 DFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYM 4106

Query: 4102 AEYIRTEMLEGDVLL------------APGFQIPPNLDYKGYHEYIDENLPPESPYLYGL 4149
             EY+      GD +                ++IP   + + + E I+      +P ++GL
Sbjct: 4107 DEYL------GDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGL 4160

Query: 4150 HPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELR 4209
            HPNAEIG+ T  +  ++  +LE+QP+  +S   +G+SR++  G                 
Sbjct: 4161 HPNAEIGYYTQAARDMWAHLLELQPQTGES--SSGISRDDYIGQ---------------- 4202

Query: 4210 RGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAK-AAEKTPYVVVAFQECERMNILTNEM 4268
                         V  +I  K+P+ F++ ++  +     +P  VV  QE ER N L   M
Sbjct: 4203 -------------VAKEIENKMPKVFDLDQVRKRLGTGLSPTSVVLLQELERFNKLVVRM 4249

Query: 4269 RRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIR 4328
             +SL EL   L GE+ ++ +++D++ +LF   +P+ W   A  ++  L  W    L R  
Sbjct: 4250 TKSLAELQRALAGEVGMSNELDDVARSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFS 4309

Query: 4329 ELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTK-KNREDM 4387
            +   W T+ + P+ +WL+G   P+S+LTA++Q+  RKN WPLD+  L  +VTK ++ +++
Sbjct: 4310 QYMLWVTE-SEPSVMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDADEV 4368

Query: 4388 TAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYEC 4447
                 +G +V GL++EGA WD + G + +++ K L   +P++ I  I   R++ +N +  
Sbjct: 4369 NERAGQGCFVSGLYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRT 4428

Query: 4448 PVYKTRIR----GPTYVWTFNLKTKEKAAKWILAAVALLL 4483
            PVY T +R    G   V+  +L T    + W+L  V L L
Sbjct: 4429 PVYTTSMRRNAMGVGLVFEADLFTTRHISHWVLQGVCLTL 4468


>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
          Length = 4427

 Score = 2162 bits (5603), Expect = 0.0
 Identities = 1363/4074 (33%), Positives = 2144/4074 (52%), Gaps = 237/4074 (5%)

Query: 479  LDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLIL 538
            LD  ++ +  DY  F   I+DL+     +    F+    +     LL     L  R  I 
Sbjct: 446  LDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFELVRDVPHGVLLLDTFHRLASREAIK 505

Query: 539  AEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQER 598
                 +   +  LF++EL        A +        P +   +   +G+ +W   L+ R
Sbjct: 506  RTYDKKAVDLYMLFNSEL--------ALVNRERNKKWPDLEPYVAQYSGKARWVHILRRR 557

Query: 599  LEVSMKHLK--HVEHPVMSGAEAKLTYQKYDEMM-ELLRCHREKIYQQWVAGVDQDCHFN 655
            ++  M  L   H    + +G E+  TYQ+  + + EL+R    K +Q+W + +D+DC   
Sbjct: 558  IDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVR----KTFQEWTSSLDKDCIRR 613

Query: 656  LGQPLI-LRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFV 714
            L  PL+ +    + ++ VNF K+L+ +  E+ Y   +   E P    ++    E  R   
Sbjct: 614  LDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWE-RLLFETPHYVVNVAERAEDLRILR 672

Query: 715  GNLELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQY-IQEVRE 773
             NL L+   YN I  ++   E  L K  +  +D K+      L W  +G   + I E R 
Sbjct: 673  ENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAFFITECRI 732

Query: 774  ILHNLQNRMQKAKQNIEGISQAMKDWSANPL-----------FERKDNKKEALLDLDGRI 822
                +Q  + + K +   I    ++ S   L            E +++++E    +  ++
Sbjct: 733  HASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREHRAAVQQKL 792

Query: 823  ANLNKRYAAVRDAGVKIQAMVAENAELFRAD--TLSLPWKDYVIYIDDMVLDEFDQFIRK 880
             NL++           +  ++  + E+F+ D   +   W  Y+I +D M+ D     ++ 
Sbjct: 793  MNLHQ----------DVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKW 842

Query: 881  SLSFLMDNMVIDESIAP--LFEIRMELDED------GLTFNPTLEVGSDRGFLALIEGLV 932
            SL  L   +  D   +P  LF++ + L  D       + F+PTL+          + G+V
Sbjct: 843  SLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQT---------LAGVV 893

Query: 933  NDIYN-----------VARLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAE 981
            NDI N           +  ++ +    R   +  +E + D+ +++ ++SS + N     +
Sbjct: 894  NDIGNHLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQ 953

Query: 982  EYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDS 1041
             Y  +++ Y  +W  N   F+  +                     +  P ++ F   I  
Sbjct: 954  NYLKTWDMYREIWEINKDSFIHRY--------------------QRLNPPVSSFVADIAR 993

Query: 1042 YEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEA 1101
            Y ++   V K E T     ++  DC   K +L+     W   F   L       L +L  
Sbjct: 994  YTEVANNVQK-EETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELHT 1052

Query: 1102 FMKVARMGLTKPLKEGDYDG----LVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYG 1157
            ++K     +++P +  +  G    LV+ + H +      A  +    P+ +   +L+ Y 
Sbjct: 1053 YLKENAEKISRPPQTLEELGVSLQLVDALKHDL------ANVETQIPPIHEQFAILEKYE 1106

Query: 1158 EEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRER 1217
              + + +   L  L   W   ++  +  K  +   +    + L      F+ K H   E 
Sbjct: 1107 VPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDFKKKAHTLLED 1166

Query: 1218 FRREAPFSFSDPNPYKSLNKVFLLKGIMEALSKSG-------GLFEVPVPDYKQLKACHR 1270
            F  +  F+ S+     +L+++  ++ ++ A+ +         G+F++  P  K L+   +
Sbjct: 1167 FEFKGHFT-SNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQPPSKDLQNLEK 1225

Query: 1271 EVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMK--TWDA 1328
            E+  L+++W++      +  +WKT ++  +  E M+       + +  L KE K   W+ 
Sbjct: 1226 ELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAKEYKDRNWEI 1285

Query: 1329 FVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKM-SEETTLADLLQLNLH 1387
                 + ++    ++  +S+L+NPA+RERHW Q+    Q +F   SE  TL  +++L + 
Sbjct: 1286 IETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMD 1345

Query: 1388 SYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLED 1447
             + +++  I   A KE  +E  L+ +  TW + +    P+   G   L+ +E + + LED
Sbjct: 1346 QHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRGTEEVFQALED 1405

Query: 1448 NQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRT 1507
            NQV L  +  S+++  F K+V  W++ LS    VI +   VQR W +LE+IF+G EDIR 
Sbjct: 1406 NQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLG-EDIRK 1464

Query: 1508 QLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYL 1567
            QLP +S  FD +N  +KA+M+   K  N + +T  PGL + L  +   L   +K+L  YL
Sbjct: 1465 QLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYL 1524

Query: 1568 ETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGL 1627
            ETKR  FPRFYF+S+ DLL+IL    +P  V  HL K FD++  L+ +           +
Sbjct: 1525 ETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAV 1584

Query: 1628 GMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEE--KPREQWIL 1685
            GM+S + EY+ F     L G VE WL  V   M  TLR  +    +   +    R++W+ 
Sbjct: 1585 GMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVK 1644

Query: 1686 DYP-------AQIWWTTEVGLAFARLEEGYENAI-KDYNKKQISQLNVLITLLIGNLNAG 1737
            ++        +QI WT +V       +E  +  I K   K Q+S LN     + GNL   
Sbjct: 1645 EWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKI 1704

Query: 1738 DRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQ 1794
             R+KI+ + TI++HARDV+ K+    +    +F W +QLR  W+++   C     + Q Q
Sbjct: 1705 MRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQ 1764

Query: 1795 YSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMV 1854
            Y+YEYLGN+ RLVITPLTDRCY+TLT +LHL  GG+P GPAGTGKTET KDLG+ALG  V
Sbjct: 1765 YNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYV 1824

Query: 1855 YVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKK 1914
             V NCSE +DYKS G +Y GLAQTGAWGCFDEFNRI++EVLSV+A Q+ C+  A+ A   
Sbjct: 1825 IVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLT 1884

Query: 1915 AFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAE 1974
             F+F G  I L+ + GIFITMNPGYAGR ELPENLK++FRP AMVVPD  LI EI+L  E
Sbjct: 1885 HFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGE 1944

Query: 1975 GFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLM 2034
            GF   ++LA+K  TLY+L  + LS+QDHYD+GLRA+ S+L  AG  +R  P   +++VL+
Sbjct: 1945 GFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLL 2004

Query: 2035 RALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFV 2094
             ++RD NI K+ + D P+F  ++ DLFP +++P        + ++Q I ++ LQ+    +
Sbjct: 2005 LSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTL 2064

Query: 2095 LKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRK-------PVAVDLDPKA 2147
             KV QL E    RHS  IVG  GSGK+   + L  +  +L R             L+PKA
Sbjct: 2065 TKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKA 2124

Query: 2148 VTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDD 2207
            ++  EL+G  +  T EW DG+ S++MR          KWI+ DG +D +WIE++N+VMDD
Sbjct: 2125 LSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDD 2184

Query: 2208 NKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIER 2267
            NKVLTL + ERI +   + L+FE+  L  A+PATVSR G++Y + ADLGW P V SW+E+
Sbjct: 2185 NKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEK 2244

Query: 2268 RKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPD 2327
            R  ++E   L  +F+K +   L   +   K++ P+PE + I ++  L   L T +     
Sbjct: 2245 RP-KAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLCKLYSALATPENGVNP 2303

Query: 2328 SPRELY----ELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDY 2383
            +  E Y    E+ FVF+  W+   ++  D+    R++    ++ E +   FP++ T+++Y
Sbjct: 2304 ADGENYVTMVEMTFVFSMIWSVCASV--DEEGRKRIDS---YLREIEG-SFPNKDTVYEY 2357

Query: 2384 YIDPDTKKFLPWTDKVP-SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGN 2442
            ++DP  + +  + DK+P S+   P+ P    +V T +T+R  Y +  L+    P++LVG 
Sbjct: 2358 FVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGP 2417

Query: 2443 AGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKK 2502
             GTGK+ +    L+SL +  + V  V  +  TTS  +Q ++E  +EK++   Y P G K 
Sbjct: 2418 VGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKS 2477

Query: 2503 LVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGS 2562
            ++ F+DD+NMP  D +G+  P  LIR  +D+  WYDR K T+K I     +A M P  G 
Sbjct: 2478 MITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGGG 2537

Query: 2563 FTIDS-RLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALAL 2621
             T+ S RL+  F +  ++FP +  +  I+ T++ Q L  +     ++ I + +  A L +
Sbjct: 2538 RTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKL--QDFEEEVKPIGNVVTEATLDM 2595

Query: 2622 HQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDK 2681
            +  +   FLPT  K HY+FNLRD+S +FQG+L +  +   T   + RLW+HE  RV+ D+
Sbjct: 2596 YNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDR 2655

Query: 2682 MVDEKDQETLHRVTMASTKKFFDDLGDELLFAK-PNIFCHFAQGIGDPK-YVPVTDMAPL 2739
            +VD  D E    +       FFD     L  +K P IF  F   + +PK Y  +TD+  L
Sbjct: 2656 LVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDF---LKEPKVYEDLTDLTVL 2712

Query: 2740 NKLLVDVLDSYNEVNAV--MNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLS 2797
              ++   L+ YN   +V  M LVLF +A+ HI RI R++  PRGN LLVG+GGSG+QSL+
Sbjct: 2713 KTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLA 2772

Query: 2798 RLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVL 2857
            RLA+ I     FQI + K Y   + + D+   Y +A V+   + F+  D+Q+A+E FL  
Sbjct: 2773 RLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLED 2832

Query: 2858 INDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCF 2917
            IN++L+SGE+P L+  DE E I S +  Q +   + ++ ++ + + IE+V+  L ++LC 
Sbjct: 2833 INNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCL 2892

Query: 2918 SPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETE-GIPWEVKASISFF 2976
            SP+G   R   R++PA+VNCT I+WF EWP++AL+ V+ + L   + G    +   ++  
Sbjct: 2893 SPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQI 2952

Query: 2977 MSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLM 3036
               +H +V + S+  L   RR+NY TP  +LE +  Y+ LL +KR EL+A+  +L  GL 
Sbjct: 2953 FVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLF 3012

Query: 3037 KLQSTASQVDDLKAKLAIQEAELKQ-KNESADQLIQVVGIEAEKVSKEKAI-ADQEEVKV 3094
            K+  T  +V  +  +L   + ++ + + +  + L+ +V  + E   ++KA+ A+ E++ V
Sbjct: 3013 KIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAV 3072

Query: 3095 EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAV 3154
            E I           + DL +A PAL  A  AL++LNK ++ E+KS+G PP  V  V  AV
Sbjct: 3073 EEIKCQALADN--AQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAV 3130

Query: 3155 MILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDP 3214
            MIL         + +W  AK  +G+   F+ SL  FDK++I +  LK    Y   P F P
Sbjct: 3131 MILRG------NEPTWAEAKRQLGE-QNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQP 3183

Query: 3215 EFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE 3274
            + I   S AA  LC W   +  +  +Y  V PKR  +  A A+L E Q  L+  + K+ E
Sbjct: 3184 DIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLRE 3243

Query: 3275 LNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQ 3334
            +   L  L   +++  A+K + +++++     +  A  LV GLA E  RW E+V+     
Sbjct: 3244 VAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEED 3303

Query: 3335 GVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDD 3394
               L GD LL +AF+SY+G F   YR+E++ + WI  I  L+VP   +  +D  + L + 
Sbjct: 3304 LGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAID--NFLCNP 3361

Query: 3395 ADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSE-LKAIRLGQ 3453
              V  WN QGLPSD  STEN  I+    RW L++D Q Q +KWIKN    + LK I L  
Sbjct: 3362 TKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQM 3421

Query: 3454 KSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKG--KYIKIGDKEVEYHPKF 3511
              YL ++E AI  G  +L++N+ E +DP L+P+L ++  + G    ++IGDKEVEY+  F
Sbjct: 3422 SDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNF 3481

Query: 3512 RLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQ 3571
            R  + TK  NPHY PE  A+ T++NF V   GLE QLL  VV KERP+LE+ K +L  + 
Sbjct: 3482 RFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINI 3541

Query: 3572 NEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKIN 3631
               K  LKELED +L  L+ A+G+ L D  LV  L T+K TA+E+ E++  ++ TE+  +
Sbjct: 3542 AAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTD 3601

Query: 3632 EARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVIN 3691
             ARE YRP A+RAS+L+F+LND+  I+P+YQFSL A+  +F  +I ++  +N+++ R+  
Sbjct: 3602 LAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDY 3661

Query: 3692 LTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVV-- 3749
            L D  TY+VY YT R LFER KL+F   +  ++L    +LN  E +F LR     GVV  
Sbjct: 3662 LNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLR----GGVVLD 3717

Query: 3750 ------SPV-DFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPK 3802
                  +P   +L    W  I  L ++  F  L +  E   + W     + APEK + P 
Sbjct: 3718 REGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPG 3777

Query: 3803 EWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSI 3861
            EW+N    +Q++ +VR LR DR+ + + +F+   +GS+F+E   +      E+S+P + +
Sbjct: 3778 EWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPL 3837

Query: 3862 FFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ 3921
             FILSPGVDP   +  L + +G      + H +SLGQGQ  +A   L     +GHWV L 
Sbjct: 3838 VFILSPGVDPTSALLQLAEHMGMA---QRFHALSLGQGQAPIAARLLREGVTQGHWVFL- 3893

Query: 3922 VRGGQHCRNIHLVARWLGTLDKKLERYST-GSHEDYRVFISAEPAPSPETHIIPQGILEN 3980
                    N HL   W+  LDK +E+      H  +R+++S+ P P       P  IL+ 
Sbjct: 3894 -------ANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPD-----FPISILQV 3941

Query: 3981 AIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQ 4040
            +IK+T EPP G+ AN+ +   L ++     C+K  ++K +LF+LC+FH+V+ ER+KF   
Sbjct: 3942 SIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQL 4001

Query: 4041 GWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTY 4100
            GWN  Y FN+ D  +S N+L  YL+   + PWD L+YL   I YGGH+TDDWDRRL  TY
Sbjct: 4002 GWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTY 4061

Query: 4101 LAEYIRTEMLEGD---VLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGF 4157
            + +Y   + L      +     + IP +     Y EYI      + P  +G HPNA++  
Sbjct: 4062 INDYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVAS 4121

Query: 4158 LTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTG 4217
                ++ LF T+L +QP+ T + AG G +REEK               LEL         
Sbjct: 4122 QITEAQTLFDTLLSLQPQITPTRAG-GQTREEKV--------------LELAA------- 4159

Query: 4218 FQVKAVLDDILEKIPETFNMAEIM-AKAAEKTPYVVVAFQECERMNILTNEMRRSLKELN 4276
                    D+ +KIPE  +        A + +P  VV  QE +R N L   +  SL +L 
Sbjct: 4160 --------DVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLE 4211

Query: 4277 LGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTD 4336
             G++G + ++T +E++   +F   VP  W  +AYPS   LAAW  DL +R+ + E W + 
Sbjct: 4212 KGIQGLIVMSTSLEEIFNCIFDAHVPPLW-GKAYPSQKPLAAWTRDLAMRVEQFELWASR 4270

Query: 4337 FALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSY 4396
               P   WL+GF  P  FLTA++QS AR+N   +D +     V+  +  ++  PP++G +
Sbjct: 4271 ARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVW 4330

Query: 4397 VYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVY 4450
            V GL++EGA WD +   + EA   +L   MP I  +     +   K +Y CP Y
Sbjct: 4331 VRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCY 4384



 Score =  107 bits (268), Expect = 2e-22
 Identities = 74/315 (23%), Positives = 147/315 (46%), Gaps = 16/315 (5%)

Query: 31  IGAEENVALFTEFFEKPDVQVLVLTLNAAGMIIPCLGFPQSLKSKGVYFIKTKSENINKD 90
           +  +E+ A+   F + P   +L + ++    +   LG P   +++ VYFI+     I  +
Sbjct: 93  VWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVYFIRQAPVPITWE 152

Query: 91  NYRARLLYGDISPTPVDQLIAVVEEVLSSLLNQSENMAGWPQVVSEDIVKQVHRLKNEMF 150
           N+ A + +G +    +  L+ ++  V +  +  +    GWP+ +       +H+    + 
Sbjct: 153 NFEATVQFGTVRGPYIPALLRLLGGVFAPQIFAN---TGWPESIRNHFASHLHKFLACLT 209

Query: 151 VMSGKIKGKTLLPIPEHLGSLDGTLESMERIPSSL--DNLLLHAIETTIIDWSHQIRDVL 208
               K++G T+L IP          E+M   P  +  D  L+  +ET++I W+ QI+++L
Sbjct: 210 DTRYKLEGHTVLYIPA---------EAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML 260

Query: 209 SKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQLNRPKVNKIVEILEKAKSCYWPAL 268
           S        + L PL ++EF  W  R ++L  I +QL +  V  +  IL  AKS Y    
Sbjct: 261 SAQETVETGENLGPLEEIEF--WRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPF 318

Query: 269 QNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQADFTMLPTFIAKVLDTICFIWATSEYY 328
             +   + +G ++A   + +L  L+   +E+       + + + K++  I  IW  S +Y
Sbjct: 319 MKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHY 378

Query: 329 NTPARIIVILQEFCN 343
           NT  R+  + ++ C+
Sbjct: 379 NTRERLTSLFRKVCD 393


>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
          Length = 4158

 Score = 1989 bits (5154), Expect = 0.0
 Identities = 1240/3777 (32%), Positives = 1975/3777 (52%), Gaps = 257/3777 (6%)

Query: 866  IDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFL 925
            I   + +E  +   K  + +++    DES+ P+F   + L    L F P+LE      FL
Sbjct: 480  IQKWITEEKPEVPDKKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLE-----DFL 534

Query: 926  ALIEGLVNDIYNVARLIPRLAKDR---------MNYKMD-------------LEDNTDLI 963
              I G VN   N    +P L  D          +N K++              ED+ +  
Sbjct: 535  DGILGAVNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFH 594

Query: 964  EMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDD 1023
             +  ++   +  A + A  Y  +FE++   + +N                 E LD     
Sbjct: 595  TIISQIKETIQAAFESARIYAATFEKFQIFFKEN-----------------ESLDL---Q 634

Query: 1024 TIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRW--- 1080
             +    P +  F EQ++ Y K +++      T+   G L  D R  ++ L+ +  R    
Sbjct: 635  ALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNV-GLLLIDTRLLREKLIPSPLRCLEV 693

Query: 1081 -GFMFKRHLSNHVTNSLADLE-AFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAA 1138
              FM  R     V   + + + A  K+  +    P    +Y   V  +  L +++ER  +
Sbjct: 694  LNFMLPRQSKKKVDAIIFEAQDAEYKLEFV----PTTTTEY---VHSLLFLDEIQERIES 746

Query: 1139 TDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVS 1198
             ++    + Q  +L++ Y    P E           +A  K   + V+  +     +  S
Sbjct: 747  LEDEGNIVTQMYKLMEQYQVPTPPEDFAV-------FATMKPSIVAVRNAIDKSVGDRES 799

Query: 1199 ILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYK---SLNKVFL----LKGIMEALSKS 1251
             +++ C        E       E      DP         +K+ L    L+ ++  L K 
Sbjct: 800  SIKQFCVHLGSDLEELNNEVN-EVKLQAQDPQILDISADQDKIRLILNNLQSVLADLQKR 858

Query: 1252 GGL-------FEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ 1304
                      F+V V  ++ L+    E++L + LWD     +   ++W  +K+  ++ E 
Sbjct: 859  AFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLKSKFDCLDPEV 918

Query: 1305 MDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQ 1364
            ++    K+AK +  L+K +        L   V+ +   L  + +L+NP ++ RHW  + Q
Sbjct: 919  LNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQ 978

Query: 1365 ATQVKFKMSE-ETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQ 1423
                    +E   TL  L QL++  +  E+++I  +A  E+ +E +LK ++ +W   EF 
Sbjct: 979  TVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVEDSWKTTEFV 1038

Query: 1424 HEPHPRT-GTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVI 1482
              PH  +    +L  ++ +   L+D+ + +  L  S+YL      V  WQ++L+  +  +
Sbjct: 1039 ILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQTL 1098

Query: 1483 SIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSK 1542
              W   QR W +LESIF  + DI+ QLP +++ F  +++ +K +M    + PN + A ++
Sbjct: 1099 EEWLTCQRNWLYLESIF-NAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQ 1157

Query: 1543 PGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHL 1602
            PGL    +     L   +K L  YLE+KR+ FPRFYF+S+ +LL+IL+   +P  V  HL
Sbjct: 1158 PGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHL 1217

Query: 1603 SKLFDSLCKLKFRL---------DASDKPLKVG----LGMYSKEDEYMVFDQECDLSGQV 1649
             K FDS+ KL+F L             +P KV     L M S E E +   +     G V
Sbjct: 1218 RKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLGKGLKARGNV 1277

Query: 1650 EVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWIL-DYPAQ-------IWWTTEVGLAF 1701
            E WL +V + M ++LR     A+  Y+ K R  W++  +P+Q       I W  ++    
Sbjct: 1278 EEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPSQVILTVSQIMWCRDLTECL 1337

Query: 1702 ARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI- 1760
                  +  A+K++ K    +LN L  ++ G+L    R  +  + TIDVHARD+V +++ 
Sbjct: 1338 ETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTALITIDVHARDIVTELVQ 1397

Query: 1761 --VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYIT 1818
              VE+ ++F WQ QLR+ WD +  +C A +  +Q  Y YEYLG  PRLVITPLTDRCY+ 
Sbjct: 1398 SKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLGACPRLVITPLTDRCYLC 1457

Query: 1819 LTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQT 1878
            L  +L L +GGAPAGPAGTGKTETTKDL +AL     VFNCS+ +DYK  G  + GLAQ+
Sbjct: 1458 LMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQS 1517

Query: 1879 GAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPG 1938
            GAW CFDEFNRI +EVLSVIA Q+  +++A  AK   F F G  I L+ T   FITMNPG
Sbjct: 1518 GAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLVMTCAAFITMNPG 1577

Query: 1939 YAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLS 1998
            YAGR ELP+NLKALFRP AM+VP++ LI E++L +EGF  +++LARK   +Y LC E LS
Sbjct: 1578 YAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKMTQMYKLCSEQLS 1637

Query: 1999 KQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIG 2058
            +QDHYD+G+RA+KSVLV+AGSLKR +P   ED VL+RAL+D N+PK +TDD  +F G+I 
Sbjct: 1638 QQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSNLPKFLTDDALLFSGIIS 1697

Query: 2059 DLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGS 2118
            DLFP + +P       +  I   +    LQ E   V KV+Q  E + VRH V +VG  G 
Sbjct: 1698 DLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGG 1757

Query: 2119 GKSQVLKSLNKTYQNLKRKPV---------AVDLDPKAVTCDELFGIINPVTREWKDGLF 2169
            GK+ V + L +T  NL++  +            L+PK++T  EL+G +N +T EWKDGL 
Sbjct: 1758 GKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLM 1817

Query: 2170 STIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVF 2229
            +  +R   N T +  KWII DG +D +WIE++NTV+DDNK+L LA++ERI L   + ++F
Sbjct: 1818 ALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLF 1877

Query: 2230 EISHLRTATPATVSRAGILYINPADLGWNPVVSSW---IERRKVQSEKANLMILFDKYLP 2286
            E+  LR A+PATVSR G+++++P +L W P V +W   I ++  +  +  ++ LF +Y+ 
Sbjct: 1878 EVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKLTEETQEYILNLFQRYVD 1937

Query: 2287 TCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEK-----TVPPDSPRELYELYFVFTC 2341
              L  +     +  P  +I+ + T+  LLE L+  K      +       +    FVF  
Sbjct: 1938 EGLHFINKKCSQAIPQVDISKVTTLCCLLESLILGKDGVNLAMEQTKLNTILCQTFVFCY 1997

Query: 2342 FWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVPS 2401
             W+ GG + ++    +   F +   ++    + P+ G ++  ++D DTK+  PW   +P+
Sbjct: 1998 LWSLGGNLTENYYDSFDT-FIRTQFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIPT 2056

Query: 2402 FELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESL-NT 2460
            F+ + DVP    LV TT+T+R  Y M+ L+     V+  G  G GKSV+    L  +  +
Sbjct: 2057 FKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQES 2116

Query: 2461 DNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGT 2520
              Y+   + F+  T+SA  Q ++E  LE+K     G PG K++V F+DD+NMP +D+YG+
Sbjct: 2117 AGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGS 2176

Query: 2521 VAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYV-ACMNPTSGSFTIDSRLQRHFCVFAVS 2579
              P  L+RQ+ D   +YDR+KL  K+I +   + AC  P  G   +  R  RHF +  + 
Sbjct: 2177 QPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLP 2236

Query: 2580 FPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYV 2639
             P + +L  I+  IL   L+      A+++ +S +V A++ ++ K++   LPT  K HYV
Sbjct: 2237 MPSEHSLKQIFQAILNGFLS--DFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYV 2294

Query: 2640 FNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMAST 2699
            FNLRDLS   QG+L      ++  + + RL+ HE +RV+ D++++ +D+   H +     
Sbjct: 2295 FNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMA 2354

Query: 2700 KKFFDDLGD-ELLFAKPNI---FCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVN- 2754
             K F    D E    KP I   F  F     D  Y  + D+     +L D LD YN  N 
Sbjct: 2355 NKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNP 2414

Query: 2755 AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLK 2814
              + LV F+DA+ H+ RI R++   RGNALLVGVGG+GKQSL+RLAA+I G    QI L 
Sbjct: 2415 KEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELS 2474

Query: 2815 KGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMED 2874
            +GY       DL   Y  A V++   VFL TD+Q+  E+FL  IN++L SGE+P LF +D
Sbjct: 2475 RGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKD 2534

Query: 2875 EVENIISSMRPQVKSLGMND-TRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPA 2933
            E+E ++++ RP+ K +G+++  R+  +++FI KVR++L ++LC SPVG   R R R FP+
Sbjct: 2535 ELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPS 2594

Query: 2934 VVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLA 2993
            +VNC  IDWF +WP +AL+SVS  F  + +    E+K  +      VH +V+ M+  Y  
Sbjct: 2595 LVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYN 2654

Query: 2994 TERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLA 3053
              RR  YTTP ++LE I LY ++L++KR ++++  +R++NGL KL  T   VD +K  L+
Sbjct: 2655 ELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLS 2714

Query: 3054 IQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLA 3113
              E  L  K+E  + L++ + ++ E   + +    ++E   +V  +         + DL 
Sbjct: 2715 ALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLD 2774

Query: 3114 KAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAA 3173
            +A PAL AA +ALD+L+K +++E++ F  PPD V+ V  A+ IL      +     W +A
Sbjct: 2775 EALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISIL------LNAKPDWPSA 2828

Query: 3174 KIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCIN 3233
            K ++G    FL  L ++DKE+I    L   + Y  NP F PE +   S A   +C W   
Sbjct: 2829 KQLLGD-SNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRA 2887

Query: 3234 IVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEK 3293
            +  +  V   V PKRQ L  A AEL      L   +  + ++   +  L   ++K   EK
Sbjct: 2888 MDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEK 2947

Query: 3294 IKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVG 3353
                +    T   ++ A +L   L  E +RW ES++ F  +   + G+V + +A V+Y G
Sbjct: 2948 ESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYG 3007

Query: 3354 YFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTE 3413
             FT +YR  L+E  WI    +L++PI  +  L  +++L D  ++  WN  GLP D +STE
Sbjct: 3008 AFTAQYRQSLIE-CWIQDCQSLEIPIDPSFSL--INILGDPYEIRQWNTDGLPRDLISTE 3064

Query: 3414 NATILGNTERWPLIVDAQLQGIKWIKNK-YRSELKAIRLGQKSYLDVIEQAISEGDTLLI 3472
            N  ++    RWPL++D Q Q  +WI+NK  +S LK I+L   ++L ++E +I  G  +L+
Sbjct: 3065 NGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLL 3124

Query: 3473 ENIGETVDPVLDPLLGRNTIKKG--KYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQA 3530
            E + ET+DP L+P+L +     G    I++GD +++Y   FR  + TK  NPHY PE+  
Sbjct: 3125 EELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCI 3184

Query: 3531 QCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLS 3590
            + T+INF VT+ GLEDQLL+ VV  E+P LE+ +  L    N  K  LK +E+ +L  L 
Sbjct: 3185 KVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLF 3244

Query: 3591 AASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFI 3650
             + GN L +  L++ L+ +K T+  I+ ++ EA+ TE  IN ARE YRP A + S++YF+
Sbjct: 3245 TSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFV 3304

Query: 3651 LNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFE 3710
            +  L++I+P+YQ+SLK F  +F   I+ +     ++QR+  L ++   + Y+  +RGLFE
Sbjct: 3305 IASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFE 3364

Query: 3711 RDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSP----VDFLQHQGWGGIKAL 3766
            + KLI+   +  +++  +  L+  E +F LR         P      +L    W     L
Sbjct: 3365 QHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDL 3424

Query: 3767 SE-MDEFKNLDSDIEG--------------SAKRWKKLVESEAPEKEIFPKE-------W 3804
             E    F  L  +I                + ++W+   + +  +K +  ++       W
Sbjct: 3425 EESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPW 3484

Query: 3805 K-NKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFF 3863
                ++  KL +++C + +++ +A+ +FV E +G +F+E   V+    Y++ S +T + F
Sbjct: 3485 SAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVF 3544

Query: 3864 ILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVR 3923
            ILS G DP+   +   ++ G+   + ++ ++SLGQGQ  +AE  +  A + G+WV LQ  
Sbjct: 3545 ILSTGSDPMGAFQRFARESGY---SERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQ-- 3599

Query: 3924 GGQHCRNIHLVARWLGTLDKKLERYS---TGSHEDYRVFISAEPAPSPETHIIPQGILEN 3980
                  N HL   W+  +++ ++ ++   +   + +R+F+S+ P     ++  P  +L+N
Sbjct: 3600 ------NCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMP-----SNTFPVTVLQN 3648

Query: 3981 AIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQ 4040
            ++K+TNEPP G+ AN+ +A    T    E      +++ ++F +C+FHA++ ER+KFG  
Sbjct: 3649 SVKVTNEPPKGLRANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPL 3708

Query: 4041 GWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTY 4100
            GWN  Y FN+ D   ++  L  Y +   K+PWD L Y+ GEI YGG +TD WD+R  RT 
Sbjct: 3709 GWNICYEFNDSDRECALLNLKLYCKEG-KIPWDALIYITGEITYGGRVTDSWDQRCLRTI 3767

Query: 4101 LAEYIRTEMLEGDVLLA-PGFQIPPNLD-YKGYHEYIDENLP-PESPYLYGLHPNAEIGF 4157
            L  +   E LE D   +  G    P  D  + + +YI ENLP  + P ++G+H NA + F
Sbjct: 3768 LKRFFSPETLEEDYKYSESGIYFAPMADSLQEFKDYI-ENLPLIDDPEIFGMHENANLVF 3826

Query: 4158 LTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTG 4217
                +  L  T+LE+QP+   S  G G S +E    L      R  E LE          
Sbjct: 3827 QYKETSTLINTILEVQPR--SSTGGEGKSNDEIVQELVASVQTRVPEKLE---------- 3874

Query: 4218 FQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNL 4277
                      +E   E+  + ++  +    T    V  QE +R N L   +  SL+ LN 
Sbjct: 3875 ----------MEGASESLFVKDLQGRLNSLT---TVLGQEVDRFNNLLKLIHTSLETLNK 3921

Query: 4278 GLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDF 4337
             + G + ++ ++E +  +   + VP  W   AYPS+  L +W  DL+LR   ++ W    
Sbjct: 3922 AIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLKR- 3980

Query: 4338 ALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNRE------------ 4385
              P + W++GFF PQ FLT  +Q+ ARK   P+D++     V    R+            
Sbjct: 3981 GQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQ 4040

Query: 4386 -------DMTAP-PREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVD 4437
                   DM  P P +G  V+G+FM+ +RWD +  VI +A   ++ P +PV+  +    +
Sbjct: 4041 FGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDALPGQMNPVLPVVHFEP-QQN 4099

Query: 4438 RMETKNIYECPVYKTRIRGPT---------YVWTFNLKTKEKAAKWILAAVALLLQV 4485
               +  +Y CP+YKT  R  T         +V T  L +K     WI    ALL Q+
Sbjct: 4100 YKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSALLCQL 4156


>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
          Length = 4265

 Score = 1981 bits (5131), Expect = 0.0
 Identities = 1170/3340 (35%), Positives = 1832/3340 (54%), Gaps = 192/3340 (5%)

Query: 1254 LFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFA 1313
            +F +P+ +Y +L    +E +   +LW          E W       I+ EQ++ +  +  
Sbjct: 1002 IFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAF 1061

Query: 1314 KDMRSLDKEMKTWDAF--VGLD--NTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVK 1369
            K M    K+ K   A   V LD    ++     +  +  L+NP +R RHW+ L     + 
Sbjct: 1062 KTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININ 1121

Query: 1370 FKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPR 1429
             +     T A  L++NL  + + +  + + A KE  +E+ L  ++  WS + F   P+  
Sbjct: 1122 VRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKA 1181

Query: 1430 TGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQ 1489
            T T +LKS +   + L+D+ V  QN+  S Y   F + + SW+ KL     V+  W   Q
Sbjct: 1182 TDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQ 1241

Query: 1490 RTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKL 1549
            R+W +LE IF  SEDI  QLP +S+R+  + + +K +M++A +   V+   S   + + L
Sbjct: 1242 RSWLYLEPIF-SSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSL 1300

Query: 1550 EALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSL 1609
                K L + +K L+EYLETKR AFPRFYF+S  +LL+ILS   DP  V  HL K F+++
Sbjct: 1301 RDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENI 1360

Query: 1610 CKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIP 1669
             +L F+ D     L++   MYS E E +        S  VE WL  V   M +++   I 
Sbjct: 1361 ARLLFQED-----LEI-THMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIE 1414

Query: 1670 EAVVTYEEKPREQWILDYPAQI-------WWTTEVGLAFARLEEGYENAIKDYNKKQISQ 1722
            +A+  Y   PR QW+L++P Q+       +WT EV  A   LE G  N       +   Q
Sbjct: 1415 KAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEA---LEAG--NLRSQLFPQLCQQ 1469

Query: 1723 LNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMIVE---SSQAFTWQAQLRHRWDE 1779
            L+ L+ L+ G L+   R  +  +  I+VHA+DVV+K+I E   S   F W +QLR+ W  
Sbjct: 1470 LSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTN 1529

Query: 1780 EKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGK 1839
               +  A   +A+  Y YEYLGN+ RLVITPLTDRCY+TLT +LHL  GGAPAGPAGTGK
Sbjct: 1530 NDLYIRA--VNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGK 1587

Query: 1840 TETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIA 1899
            TETTKDLG+AL     VFNCS+Q+D+ + G  +KGLA  GAW CFDEFNRI +EVLSV+A
Sbjct: 1588 TETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVA 1647

Query: 1900 VQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMV 1959
             Q+  +Q A + + + F F G  I L+P+  +FITMNPGYAGR ELP+NLKALFRP AM+
Sbjct: 1648 QQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMM 1707

Query: 1960 VPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGS 2019
            VPD+ +I EI L + GF EA +LA+K  T + L  E LS QDHYD+G+RA+K+V+  AG+
Sbjct: 1708 VPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGN 1767

Query: 2020 LKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNF---EK 2076
            LKR +PS  E+ + +RA+RD N+PK + +DL +F G++ DLFP +   ++ D ++   ++
Sbjct: 1768 LKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTI---KEEDTDYGILDE 1824

Query: 2077 IIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKR 2136
             I+++     L+  + F+ K +QL E   VRH + +VG  GSGKS   + L     +LK 
Sbjct: 1825 AIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKG 1884

Query: 2137 KPV-------AVD---LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKW 2186
            +P        AV+   L+PK++T  +L+G  + +T EW DG+FS+ +R  A  +    KW
Sbjct: 1885 QPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKW 1944

Query: 2187 IILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAG 2246
             + DG +D +WIE++NTV+DDNK L L+S E I L   M ++FE+  L  A+PATVSR G
Sbjct: 1945 YMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCG 2004

Query: 2247 ILYINPADLGWNPVVSSWIERRK--VQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPE 2304
            ++Y+ P+ LG  P +  W+ +    ++  + +   LF  +L   +  +R   K++     
Sbjct: 2005 MVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTN 2064

Query: 2305 ITVIQTILYLLECLLTE-------KTVPPDSPRELYEL---YFVFTCFWAFGGAMFQDQL 2354
              +  ++L LL+C           K +P +    + EL   +F+F+  W+ G        
Sbjct: 2065 CNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSG- 2123

Query: 2355 VDYRVEFSKW----WINEFKTIKFPSQGTIFDYYIDP----------DTKK------FLP 2394
               R  FS W      NE  T+ FP +G +FDY ++           D ++      ++ 
Sbjct: 2124 ---RTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVK 2180

Query: 2395 WTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDK 2454
            W D    F + PD      +V T +T+++ + +D+L+    PV+ +G  GTGK++ + DK
Sbjct: 2181 WMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDK 2240

Query: 2455 LESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPE 2514
            L      +Y+   + F+  T++   Q  ++  L+K+    +GPP  +  ++FIDD+NMP 
Sbjct: 2241 LLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPA 2300

Query: 2515 VDKYGTVAPHTLIRQHMDHRHWYDRHKL-TLKDIHNCQYVACMNPTSGSF-TIDSRLQRH 2572
            ++ YG   P  L+RQ MDH  WYDR  +   K++ +  +V  M P  G   T+  RL RH
Sbjct: 2301 LETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRH 2360

Query: 2573 FCVFAVSFPGQEALTTIYNTILTQHL-------AFRSV---SMAIQRISSQLVAAALALH 2622
            F   + +   + +   I++TIL   L       ++R     +  I   +  LV A + ++
Sbjct: 2361 FNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVY 2420

Query: 2623 QKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKM 2682
              IT+  LPT  K HY FNLRDLS +FQG+L +    ++  + L+RLW HE  RV+ D++
Sbjct: 2421 ATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRL 2480

Query: 2683 VDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPK-YVPVTDMAPLNK 2741
            V+E+D+    ++     +++         F +P ++  F     D K Y  +T  + + +
Sbjct: 2481 VNEEDRSWFDQLLKRCMEQWEVTFNKVCPF-QPILYGDFMSPGSDVKSYELITSESKMMQ 2539

Query: 2742 LLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLA 2800
            ++ + ++ YN++N A + LVLF DA++HICRI+R L    GNALL+GVGGSG+ SL+RLA
Sbjct: 2540 VIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLA 2599

Query: 2801 AYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLIND 2860
            ++++  + FQI L K YG+ + + D+    +KA ++N+P  FL +D+Q+  E FL  IN+
Sbjct: 2600 SHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINN 2659

Query: 2861 LLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPV 2920
            +L SG+IP L+  DE + I+S+MRP ++  G+  T+      +  +VR  + ++LC SP+
Sbjct: 2660 VLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMSPI 2719

Query: 2921 GSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEET---EGIPWEVKASISFFM 2977
            G V R R R+FP++VNC  IDWF+EWP +AL SV+  FL E    E    E++  I   +
Sbjct: 2720 GEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCV 2779

Query: 2978 SYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMK 3037
             Y+H +V++    YLA   R+NY TPK++LE + ++  L+ +K+ EL     R+++GL K
Sbjct: 2780 -YIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDK 2838

Query: 3038 LQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVI 3097
            L  T+  V  ++  L      L++  +     ++ + ++     + +     EE+K    
Sbjct: 2839 LLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEK 2898

Query: 3098 NKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMIL 3157
             K         + DL +A PAL AA  +L  LNKN++TE+++   PP  V  V  AV I+
Sbjct: 2899 AKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIM 2958

Query: 3158 TA----------PGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQ 3207
                        PG K+  D  W+  K ++     FL+SL KFDK++I +  +KA +PY 
Sbjct: 2959 KGIKPKKVPGEKPGTKV--DDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYI 3016

Query: 3208 GNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSR 3267
             N  F P  I   S A   +C W   + +++ V   V PKRQAL EA  +L   Q  L  
Sbjct: 3017 DNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDE 3076

Query: 3268 IKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAES 3327
             K ++ E+   ++ + + + +   +K + + + +   + +  A +L+ GL+ E +RW E+
Sbjct: 3077 AKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQET 3136

Query: 3328 VENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDP 3387
            VEN +     + GDVL+ + FV+Y+G FT +YR  L +  W+  + +  VP   T+    
Sbjct: 3137 VENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDS-WVKQLRSHNVPH--TSEPTL 3193

Query: 3388 LSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSE-L 3446
            +  L +   + +W   GLP+D +S EN  I   ++RW   +D Q Q  KWIKN  +   L
Sbjct: 3194 IGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGL 3253

Query: 3447 KAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKK--GKYIKIGDKE 3504
               +L  + +L  +E AI  G   L+EN+GE +DP L+P+L + T K+     +K+GD  
Sbjct: 3254 DVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTV 3313

Query: 3505 VEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLK 3564
            + YH  FR+ + TK  NPHY PE+  + TLINF ++  GLEDQLL  VVA+ERPDLE+ K
Sbjct: 3314 IPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAK 3373

Query: 3565 ANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAK 3624
              L  S  + +  LK++ED +L RLS++ GN + D  L++ LE +K  A+EI+ KV  A+
Sbjct: 3374 NQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAE 3433

Query: 3625 ITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANE 3684
             TE  I+  R  Y P A R  +L+F ++DL  ++P+YQ+SL+ F  +F   I  +  A+ 
Sbjct: 3434 QTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADN 3493

Query: 3685 VKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPF 3744
            +K+R+ N+   +TYS+Y    R LFE+ KL+F   +  +++  + ++N  E  +LL    
Sbjct: 3494 LKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLL---- 3549

Query: 3745 KAGVVSPV------DFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKE 3798
              G +S +      D+L  + W  I ALS +  F +  SD       ++ + +S  P +E
Sbjct: 3550 SGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHRE 3609

Query: 3799 IFPKEWKNKT-ALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSP 3857
              P  W       QKL ++RCLR D++T A+++FV   +  +F+E ++   S  +++S+ 
Sbjct: 3610 PLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNS 3669

Query: 3858 STSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHW 3917
            +T + F+LSPG DP  D+    +++ F+    KL  +SLGQGQ   AE  +  + E+G W
Sbjct: 3670 TTPLIFVLSPGTDPAADLYKFAEEMKFS---KKLSAISLGQGQGPRAEAMMRSSIERGKW 3726

Query: 3918 VILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGS-HEDYRVFISAEPAPSPETHIIPQG 3976
            V  Q        N HL   W+  L++ +E  +    H D+R+++++ P+        P  
Sbjct: 3727 VFFQ--------NCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNK-----FPVS 3773

Query: 3977 ILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRK 4036
            IL+N  K+T EPP G+ ANL K+     +D L  C K MEFK +L +LC FH    ERRK
Sbjct: 3774 ILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRK 3833

Query: 4037 FGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRL 4096
            FG  G+N  Y F +GDL I I+ L  +L+    +P+  L+Y  GEI YGG +TDDWDRR 
Sbjct: 3834 FGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRC 3893

Query: 4097 CRTYLAEYIRTEMLEGDVLLAPG---FQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNA 4153
                L ++   ++L  +   +      QIPP  D  GY  YI      + P ++GLH NA
Sbjct: 3894 IMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNA 3953

Query: 4154 EIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGC 4213
             I F    +  L  T++++QPK + +G+     REE                        
Sbjct: 3954 NITFAQNETFALLGTIIQLQPKSSSAGSQ---GREEI----------------------- 3987

Query: 4214 PGTGFQVKAVLDDILEKIPETFNMAEIMAK--AAEKTPYVVVAFQECERMNILTNEMRRS 4271
                  V+ V  +IL K+PE  N+  +MAK     +     V  QE  R N L   + ++
Sbjct: 3988 ------VEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQT 4041

Query: 4272 LKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELE 4331
            L++L   LKG + +++ +E ++ +L+ +TVP+ W A+AYPS+  L++W  DLL R+  L+
Sbjct: 4042 LQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQ 4101

Query: 4332 AWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPP 4391
            AW  D  +P   W++GFF PQ+FLT  +Q+ ARK    +D +    +V  +   ++T  P
Sbjct: 4102 AWIQD-GIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRP 4160

Query: 4392 REGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYK 4451
            + G Y++GLF+EGARWD +   +AE++ KEL   M VI++   P  + + ++ Y CP+YK
Sbjct: 4161 QVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYK 4220

Query: 4452 TRIRGPT---------YVWTFNLKTKEKAAKWILAAVALL 4482
            T  R  T         YV    + T +    WI   VAL+
Sbjct: 4221 TLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALI 4260


>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
          Length = 4024

 Score = 1946 bits (5040), Expect = 0.0
 Identities = 1225/3730 (32%), Positives = 1949/3730 (52%), Gaps = 248/3730 (6%)

Query: 897  PLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRL-----AKDRMN 951
            P F +R+ LD D + F P L    D  FL + + ++  +  V R+  +L     +K +  
Sbjct: 400  PGFIMRLILDNDTIKFEPELSDYIDI-FLNVYDVMIKAVSFVPRVETKLYSKWESKSKPT 458

Query: 952  YKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCA 1011
                +  N  +   +E++  +++       E+   +++Y +L T   +  + NFL     
Sbjct: 459  TLKPIILNEIVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFL----- 513

Query: 1012 VTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQ 1071
              AE+              +  +  ++I  Y+KL EE+       +  G  +  C    +
Sbjct: 514  --AEN-------------HSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIR 558

Query: 1072 ALLSTI-----RRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVM 1126
            AL+        +    MF+ H    V   L D   F ++A   L+ P    +   L+E+ 
Sbjct: 559  ALVKRADIICGKLLAKMFRDH--QEVNTRLCD--EFERIAEKALSTPPNTAE---LMEMK 611

Query: 1127 GHLMKVKERQAAT-DNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQV 1185
             ++ KV+       +      K  +  L  Y    P ++ L       +    +      
Sbjct: 612  AYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHR 671

Query: 1186 KLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSD-PNPYKSLNKVFLLKGI 1244
            K+    ++  +   L+ +C++F  +   + ++   E  +SF D  +  + L K  +L G 
Sbjct: 672  KIIKEKIEQYQEG-LKLRCERFVEELESYAKQ--SEEFYSFGDLQDVQRYLKKAQILNGK 728

Query: 1245 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKE-------LWDMVVVVNTSIEDWKTTKW 1297
            ++  +     F      +  L + + + + +++       L++  V  +++   W    +
Sbjct: 729  LDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPY 788

Query: 1298 KDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRA----VSELQNPA 1353
              +N +Q++ D   + + +  L+K        + +   V++ +   +     +  + NP 
Sbjct: 789  HKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPG 848

Query: 1354 IRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKAL 1413
            +R RHW+ +        + S+++T++  L +NL  Y D    I + A KE  +EK ++ +
Sbjct: 849  LRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKM 908

Query: 1414 DSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQ 1473
             + W  +EF    +  TGT +L S + +   L+D+ ++ Q +  S ++  + K++  W+ 
Sbjct: 909  ITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEG 968

Query: 1474 KLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKT 1533
            KL     ++  W +VQ TW +LE IF  S DI +Q+P + +RF  +++ ++ +M   ++ 
Sbjct: 969  KLLLLQEILDEWLKVQATWLYLEPIF-SSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQD 1027

Query: 1534 PNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGN 1593
             +V+   +   +  +L+   + L +  K L EYLE KRL FPRF+F+S+ +LL+ILS   
Sbjct: 1028 KHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETK 1087

Query: 1594 DPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWL 1653
            DP  V  HL K F+ + K++F        +K   G   +  E +         GQVE WL
Sbjct: 1088 DPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEG---EVVELIEIISTAKARGQVEKWL 1144

Query: 1654 NRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYP-------AQIWWTTEVGLAFARLEE 1706
              +   M +++     +A   Y +  R  W+ D+P       +QI+WT EV  A     +
Sbjct: 1145 VELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIK 1204

Query: 1707 GYENAIKDYNKKQISQLNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI---VES 1763
              E  +K  N+    Q++ ++TL+ G L+  +R+ +  +  +DVHARDV++ ++   +  
Sbjct: 1205 ALEQYLKTCNR----QIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISD 1260

Query: 1764 SQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSL 1823
               F W +QLR+ W E   H    + +A ++Y YEYLGN+PRLVITPLTDRCY TL  +L
Sbjct: 1261 DSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGAL 1318

Query: 1824 HLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGC 1883
            HL +GGAP GPAGTGKTETTKDL +A+     VFNCS+ +DY + G  +KGL   GAW C
Sbjct: 1319 HLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWAC 1378

Query: 1884 FDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRA 1943
            FDEFNRI +EVLSV+A Q+  +Q  I A      F G  + L PT  +FITMNPGYAGR+
Sbjct: 1379 FDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRS 1438

Query: 1944 ELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHY 2003
            ELP+NLKALFR  AM+VPD+ +I EI+L + GF+ AR L+ K +  Y LC E LS Q HY
Sbjct: 1439 ELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHY 1498

Query: 2004 DWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPA 2063
            D+G+RA+KSVL  AG+LK   P+  E+ +L+R++ D N+PK ++ DLP+F G+  DLFP 
Sbjct: 1499 DYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPG 1558

Query: 2064 LDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQV 2123
            + +P+    +    IK +   + LQ    F  K++Q+ E++ VRH   IVG    GK+  
Sbjct: 1559 VKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSA 1618

Query: 2124 LKSLNKTYQNLKRKPVAVD-------LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDL 2176
             + L     ++  K +  +       L+PK+VT  +L+G  + V+ EW DG+ +   R  
Sbjct: 1619 YRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAF 1678

Query: 2177 ANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRT 2236
            A+      KW+I DG +D +WIE++NTV+DDNK L L S E I ++  M L+FE   L  
Sbjct: 1679 ASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEV 1738

Query: 2237 ATPATVSRAGILYINPADLGWNPVVSSWIERRKVQ---SEKANLMILFDKYLPTCLDKLR 2293
            A+PATVSR G++Y+ P  LGW P++ SW+          +K  +M LFD+ +P  ++ +R
Sbjct: 1739 ASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIR 1798

Query: 2294 FGFKKITPVPEITVIQTILYLLECLL----TEKTVPPDSPRELYEL---YFVFTCFWAFG 2346
               K+++P  +  ++++++ L++C +     E  +   + RE Y L    F+F+  W+ G
Sbjct: 1799 KHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVG 1858

Query: 2347 GAMFQDQLVDY--------RVEFSKWWINEFK-------------TIKFPSQGTIFDY-Y 2384
             +   D  + +            S    N FK             T+ FP +GTI+DY +
Sbjct: 1859 ASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQF 1918

Query: 2385 IDPDTKKFLPWTDKVPSFELDP-DVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNA 2443
            +     K+ PW  K+      P DV     +V T +TIR    M+LL     P + VG  
Sbjct: 1919 VTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPT 1978

Query: 2444 GTGKSVLMGD-KLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKK 2502
            GTGKSV + +  L  LN + Y    + F+  TT+A  Q ++   L+K+    +GPP  K+
Sbjct: 1979 GTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKR 2038

Query: 2503 LVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGS 2562
            +V F+DD+NMP  + YG   P  L+RQ +DH +WYD    ++  + + Q +  M P  G 
Sbjct: 2039 MVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGG 2098

Query: 2563 FT-IDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAF-RSVSMAIQRISSQLVAAALA 2620
               +  R  RHF +  ++    +++ TI++ ILT HL            +++Q+V   + 
Sbjct: 2099 RNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMT 2158

Query: 2621 LHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGD 2680
            L+++     LPT  K HY+FNLRD S + QG+  S  E  +T   + RLW+HE  RVY D
Sbjct: 2159 LYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYD 2218

Query: 2681 KMVDEKDQETLHRVTMASTKKF----FDDLGDELLF----------AKPNIFCHFAQGIG 2726
            +++D  D+  L        + +    F +L   L F           +  +FC F     
Sbjct: 2219 RLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDF----H 2274

Query: 2727 DPK-----YVPVTDMAPLNKLLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPR 2780
            DPK     Y  + D+  L  ++   L+ YN ++   MNLVLF  A+ HI RI+RIL+ PR
Sbjct: 2275 DPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPR 2334

Query: 2781 GNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPS 2840
             +ALLVGVGGSG+QS++RLAA+++   VFQ+ + KGY   +   DL     K A   +  
Sbjct: 2335 SHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQG 2394

Query: 2841 VFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSM----RPQVKSLGMNDTR 2896
            VFL TD+Q+ EE FL  +++LL +GEIP LF  DE + I   M    R + K+   + + 
Sbjct: 2395 VFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSP 2454

Query: 2897 ETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSA 2956
               +  FI+  R QL V+L  SP+G   R R RKFPA+VNC  IDWF  WPEDAL +V++
Sbjct: 2455 IALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVAS 2514

Query: 2957 RFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNL 3016
            RFLEE E +  E++          HT+  ++S+ +    +RYNY TP ++LE I  ++ L
Sbjct: 2515 RFLEEIE-MSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLL 2573

Query: 3017 LAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIE 3076
            L KKR+E++   +R E GL KL S +SQV  ++ +L     +LK  ++  D+++ ++  E
Sbjct: 2574 LEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKE 2633

Query: 3077 AEKVSK-EKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLT 3135
            + +V+K EK +   E +  E    +   K + C+ DLA A P L +A  ALDTL   ++T
Sbjct: 2634 SVEVAKTEKIVKADETIANEQAMASKAIKDE-CDADLAGALPILESALAALDTLTAQDIT 2692

Query: 3136 ELKSFGSPPDAVVNVTAAVMIL-----------TAPGGKIPKDKSWKAAKIMMGKVDTFL 3184
             +KS  SPP  V  V  A+ IL           T  G KI  +  W  AK ++G +  FL
Sbjct: 2693 VVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKI--EDFWGPAKRLLGDM-RFL 2749

Query: 3185 DSLKKFDKEHIPEACLKAF-KPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCD 3243
             SL ++DK++IP A +    K Y  NP F PE IR+ STAA GLC W I +  + +V   
Sbjct: 2750 QSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKI 2809

Query: 3244 VAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADAT 3303
            VAPK+  L  A  EL  A + L + +  + E+   L+ L    E    +K   + + D  
Sbjct: 2810 VAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLC 2869

Query: 3304 NRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNEL 3363
            ++ +  A +L+GGL  E  RW+ +        + L GD+L+ S  V+Y+G FT  YR   
Sbjct: 2870 SKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQN- 2928

Query: 3364 MEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTER 3423
              K W          IP ++    +  L +   + TWN  GLPSD  S +N  I+ N  R
Sbjct: 2929 QTKEWTTLCKGR--DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARR 2986

Query: 3424 WPLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPV 3482
            WPL++D Q Q  KWIKN  + + L  I+L +  Y+  +E  I  G  +L+EN+GE +DP+
Sbjct: 2987 WPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPI 3046

Query: 3483 LDPLLGRNTIKKG--KYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVT 3540
            L+PLL + T K+G    I++GD  +EY P FR  + TK  NPHY PE   + TL+NF++T
Sbjct: 3047 LEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMIT 3106

Query: 3541 RDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDT 3600
             +G++DQLL  VVA+ERPDLE+ K  L     E K  LKE+ED +L  LS++ GN L D 
Sbjct: 3107 PEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDE 3166

Query: 3601 ALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPV 3660
              ++ L ++K  A+EI +K   A+ TE KI+  R  YRP A  +S+L+F L DL  I P+
Sbjct: 3167 TAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPM 3226

Query: 3661 YQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQV 3720
            YQ+SL  F  +F  +I+ +  +  + +R+  L D  TYS+Y+   R LFE+DKL+F   +
Sbjct: 3227 YQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCL 3286

Query: 3721 TFQVLSMKKELNPVELDFLLRFPFKAGVVSP----VDFLQHQGWGGIKALSEMDEFKNLD 3776
            T  +L  ++ +N  E  FLL      G+ +P      +L  + W  I  L ++  FK + 
Sbjct: 3287 TINLLLHERAINKAEWRFLLTGGI--GLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIR 3344

Query: 3777 SDIEGSAKRWKKLVESEAPEKEIFPKEWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEK 3835
             +       WKK+ +S  P  E+FP+EW++K    Q++ ++RCLRPD++   ++ F+  +
Sbjct: 3345 REFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINR 3404

Query: 3836 MGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVS 3895
            +G  F+E    + +K++ +S+    + F+LSPG DP+  +       G+     KL ++S
Sbjct: 3405 LGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGY--GGSKLSSLS 3462

Query: 3896 LGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGS-HE 3954
            LGQGQ  +A   L+ A ++G WV+LQ        N HL   W+ TL+K  E  S  S H 
Sbjct: 3463 LGQGQGPIAMKMLEKAVKEGTWVVLQ--------NCHLATSWMPTLEKVCEELSPESTHP 3514

Query: 3955 DYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKAL---DLFTQDTLEMC 4011
            D+R+++++ P+P+      P  +L+N +K+TNE P G+ AN+ ++     +   +    C
Sbjct: 3515 DFRMWLTSYPSPN-----FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSC 3569

Query: 4012 TKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVP 4071
             K  EFK +L+ LC+FHA+V ERRKFG  GWN  Y FN  DL IS+  L+ +L    ++P
Sbjct: 3570 KKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELP 3629

Query: 4072 WDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG---FQIPPNLDY 4128
            ++ LRY+ GE  YGG +TDDWDRR  R+ L ++   E++E           + +PP+ D+
Sbjct: 3630 YEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDH 3689

Query: 4129 KGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSRE 4188
            K Y EY        +P ++G++ NA+I      ++ LF  +L  Q +   +GAG   S E
Sbjct: 3690 KSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSR--SAGAGAKSSDE 3747

Query: 4189 EKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKT 4248
                                           V  V  DIL K+P  F++   M +    T
Sbjct: 3748 ------------------------------VVNEVASDILGKLPNNFDIEAAMRR--YPT 3775

Query: 4249 PYV----VVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDT 4304
             Y      V  QE  R N L   +R S   +   +KG   ++TD+E++ +++    +P+ 
Sbjct: 3776 TYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEM 3835

Query: 4305 WVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMAR 4364
            W+ ++YPS+  L ++  D L R++ L+ W  +   P   WL+GFF  Q+FLT   Q+ AR
Sbjct: 3836 WMGKSYPSLKPLGSYVNDFLARLKFLQQW-YEVGPPPVFWLSGFFFTQAFLTGAQQNYAR 3894

Query: 4365 KNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTP 4424
            K   P+D +    EV +   ++   PP +G +++GLF++GA W+ +   +AE+  K L  
Sbjct: 3895 KYTIPIDLLGFDYEVMED--KEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYD 3952

Query: 4425 AMPVIFIKAIPVDRMETKNIYECPVYKTRIR---------GPTYVWTFNLKTKEKAAKWI 4475
             +PV+++K      +  +  Y  P+YKT  R            +V    L + +    WI
Sbjct: 3953 TVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWI 4012

Query: 4476 LAAVALLLQV 4485
               VALL Q+
Sbjct: 4013 GRGVALLCQL 4022


>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
          Length = 4624

 Score = 1921 bits (4977), Expect = 0.0
 Identities = 1188/3643 (32%), Positives = 1930/3643 (52%), Gaps = 188/3643 (5%)

Query: 929  EGLVNDIYNVARLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFE 988
            E  + D   +A +   +     NY  ++ +N +++++   +S+++ +  KE     D F+
Sbjct: 1083 ENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKEVITSMDCFK 1142

Query: 989  RYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEE 1048
            RY+++W    +E +K F+                       P L++F+ QI  ++ L +E
Sbjct: 1143 RYNHIWQKGKEEAIKTFITQS--------------------PLLSEFESQILYFQNLEQE 1182

Query: 1049 VSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARM 1108
            ++  E   V  G +       K AL +  + W  +  RH +    + + ++   ++    
Sbjct: 1183 IN-AEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEFNK 1241

Query: 1109 GLTKPLKEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKL 1168
             L +P+K  D D +   M  L +++E Q + D    P++++  LL  YG  +  E   K+
Sbjct: 1242 KLNRPIK--DLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKV 1299

Query: 1169 QELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSD 1228
              L   W      A +V+  +  LQ +    L    + F    H+F   +    P + S 
Sbjct: 1300 DTLHYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMA-SG 1358

Query: 1229 PNPYKSLNKVFLLKGIMEALSK-----SGG--LFEVPVPDYKQLKACHREVRLLKELWDM 1281
              P ++ +++ + +   + + +     +GG  LF +P   Y QL    +++ LL++++ +
Sbjct: 1359 LKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTL 1418

Query: 1282 VVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVIT 1341
               V  ++  +    W ++N+E+++ +  +F    R L + +K W AF+ L   + +   
Sbjct: 1419 YNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSE 1478

Query: 1342 SLRAVSELQNPAIRERHWQQLMQATQVKFKMSEET-TLADLLQLNLHSYEDEVRNIVDKA 1400
                +  + + A+ ERHW+++   T     +  E+  L ++++  L  Y++E+ +I   A
Sbjct: 1479 CCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISA 1538

Query: 1401 VKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLK--SSEVLVETLEDNQVQLQNLMMS 1458
            VKE  +E+ LK + + W    F        G ++L+  S+  ++  +ED+ + L +L+ +
Sbjct: 1539 VKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSLMLLGSLLSN 1598

Query: 1459 KYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDD 1518
            +Y   F  ++  W Q LS +  +I  W  VQ  W +LE++F+G  DI  QLP +++RF +
Sbjct: 1599 RYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGG-DIAKQLPKEAKRFSN 1657

Query: 1519 INQEFKALMEDAVKTPNVVEA-TSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRF 1577
            I++ +  +M  A + P+VV+       L   L  L   L IC+K+L  YLE KRL FPRF
Sbjct: 1658 IDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRF 1717

Query: 1578 YFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYM 1637
            +FVS   LL+IL   +D   +  HL  +FD++  +KF     D+ L +     S+E E +
Sbjct: 1718 FFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRILSIS----SQEGETI 1773

Query: 1638 VFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPRE--QWILDYPAQIW--- 1692
              D+     G VEVWLN +L+   S+L   I +A    +E   +  +++  +PAQ+    
Sbjct: 1774 ELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSSFPAQVGLLG 1833

Query: 1693 ----WT--TEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRMKIMTIC 1746
                WT  +E  L  A+ ++     ++  N+  +  LN LI +   +L++ +R+K  T+ 
Sbjct: 1834 IQMIWTRDSEEALRNAKFDK---KIMQKTNQAFLELLNTLIDVTTRDLSSTERVKYETLI 1890

Query: 1747 TIDVHARDV---VAKMIVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNT 1803
            TI VH RD+   +  M ++S   F W  Q R  ++E+      +I D    Y  E+LG T
Sbjct: 1891 TIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCT 1950

Query: 1804 PRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQM 1863
             RLVITPLTDRCYITL Q+L + MGGAPAGPAGTGKTETTKD+GR LG  V VFNCS+QM
Sbjct: 1951 DRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQM 2010

Query: 1864 DYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFL-GEI 1922
            D++  G I+KGLAQ+G+WGCFDEFNRI + VLSV A Q+  +    +  KK+F F  G+ 
Sbjct: 2011 DFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDN 2070

Query: 1923 IGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLL 1982
            + + P  G+F+TMNPGYAGR ELPENLK  FR  AM+VPD ++I  + L + GF++  +L
Sbjct: 2071 VTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVL 2130

Query: 1983 ARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNI 2042
            ARKF TLY LC+E LSKQ HYD+GLR I SVL   G+ KR +P   E  ++MR LRD N+
Sbjct: 2131 ARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNL 2190

Query: 2043 PKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEE 2102
             K++ +D P+F+ LI DLFP + + +      E  I + + E  L     + LKV+QL E
Sbjct: 2191 SKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFE 2250

Query: 2103 LLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTR 2162
              +VRH +  +G +G+GK+  + +L +   +  +    + ++PKA+T  ++FG ++  T 
Sbjct: 2251 TQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFGRLDVATN 2310

Query: 2163 EWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLN 2222
            +W DG+FST+ R           WIILDG +D +WIE+LN+V+DDNK LTLA+ +RIP+ 
Sbjct: 2311 DWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMA 2370

Query: 2223 RTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFD 2282
               +++FE  ++  A+PATVSR G+++++ + L W+P++  ++++R  Q  +    IL  
Sbjct: 2371 PNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAE----ILRQ 2426

Query: 2283 KYLPTCLDKLRFGFKKIT---PVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVF 2339
             Y  +  D  RF  + +     V E  VI   + +L+ L+  K    +  +      FVF
Sbjct: 2427 LYTESFPDLYRFCIQNLEYKMEVLEAFVITQSINMLQGLIPLKEQGGEVSQAHLGRLFVF 2486

Query: 2340 TCFWAFGGAMFQDQLVDYRVEFSKWWINE-FKTIKFPSQG----TIFDYYIDPDTKKFLP 2394
               W+ G A+     +D R     W  +    T++ P       T FDYY+ PD   +  
Sbjct: 2487 ALLWSAGAALE----LDGRRRLELWLRSRPTGTLELPPPAGPGDTAFDYYVAPDGT-WTH 2541

Query: 2395 WTDKVPSFELDPDVPLQ--ASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMG 2452
            W  +   +    D   +  + LV   + +R  + +  + ++   V+L+G  GT K+V++ 
Sbjct: 2542 WNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIK 2601

Query: 2453 DKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNM 2512
              +   + + ++++++ F+  TT  M Q  +E  ++K+ G  YGPP  KK+  FIDD+NM
Sbjct: 2602 GFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNM 2661

Query: 2513 PEVDKYGTVAPHTLIRQHMDHRHWYDRHKL-TLKDIHNCQYVACM-NPTSGSFTIDSRLQ 2570
            P ++++G    + ++RQ M+   +Y+  K      I + Q++A M +P  G   I  RL+
Sbjct: 2662 PIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLK 2721

Query: 2571 RHFCVFAVSFPGQEALTTIYNTILTQHLAF-RSVSMAIQRISSQLVAAALALHQKITATF 2629
            R F +F  + P + ++  I+  I   H    R  S  ++   ++LV     L Q      
Sbjct: 2722 RQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKM 2781

Query: 2630 LPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQE 2689
            LPT  KFHYVFNLRDLS ++QG+L +T+EV+K P DL++LW HE +RV  D+     D  
Sbjct: 2782 LPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVT 2841

Query: 2690 TLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGD----------------PK-YVP 2732
               +  ++  ++ F +  ++ L     I  +F   + D                PK Y P
Sbjct: 2842 WFDKALVSLVEEEFGE--EKKLLVDCGIDTYFVDFLRDAPEAAGETSEEADAETPKIYEP 2899

Query: 2733 VTDMAPLNKLLVDVLDSYNEV--NAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGG 2790
            +   + L + L   L  YNE    A M++V F DA+ H+ +I+R++ +P+GNALLVGVGG
Sbjct: 2900 IESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGG 2959

Query: 2791 SGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVA 2850
            SGKQSL+RLA++I+G   FQITL + Y   +L  DL   Y  A  +     F+ TD+++ 
Sbjct: 2960 SGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIK 3019

Query: 2851 EEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMN--DTRETCWKFFIEKVR 2908
            +E FL  +N++L+SGE+  LF  DE++ I S +   +K        T E    +F+ +VR
Sbjct: 3020 DESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNENLHDYFMSRVR 3079

Query: 2909 RQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETE-GIPW 2967
            + L ++LCFSPVG   R RA KFPA+++   IDWF  WP+DALV+VS  FL   +     
Sbjct: 3080 QNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSL 3139

Query: 2968 EVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAK 3027
            E+K  +   M      V E    Y    RR  + TPK++L  I+ Y+ +  +K  E+   
Sbjct: 3140 EIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTL 3199

Query: 3028 IERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIA 3087
              R+  GL KL+  +  V  L  +L  +E EL+  N+ AD +++ V ++A+   K KA  
Sbjct: 3200 ANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEV 3259

Query: 3088 DQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAV 3147
             + + + + I  ++++ +   E  L  A+PAL  A+ AL T+  +++  +++ G PP  +
Sbjct: 3260 QKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLI 3319

Query: 3148 VNVTAAVMIL---TAPGGKIPKDKS-----WKAAKIMMGKVDTFLDSLKKFDKEHIPEAC 3199
            + +   V++L        KI  +KS     W+ +  +M     FL +L++F K+ I E  
Sbjct: 3320 MRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLM-TAGNFLQNLQQFPKDTINEEV 3378

Query: 3200 LKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELA 3259
            ++   PY   P ++ E  +      AGLCSW   +  F+ +  +V P +  L        
Sbjct: 3379 IEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHL 3438

Query: 3260 EAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLAS 3319
             A + L + + ++ +  A L  + + +E+A  EK    ++A+     +  A+ L+ GLA 
Sbjct: 3439 LAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAG 3498

Query: 3320 ENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPI 3379
            E  RW E  + F +Q   L GDVLL +AF+SY G F +++R+ L+   W   +   K  I
Sbjct: 3499 EKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLND-WRKEMKARK--I 3555

Query: 3380 PITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIK 3439
            P    L+   +L D   ++ WN QGLP+D +S +N  I+    R+PL++D Q QG  WIK
Sbjct: 3556 PFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIK 3615

Query: 3440 NKY-RSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKY- 3497
            NK  R+EL+   L  K + + +E ++S G  LLIE++GE +DP LD +L RN IK G   
Sbjct: 3616 NKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGSTF 3675

Query: 3498 -IKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKE 3556
             +K+GDKEV+    FRL + TK  NP Y PE+ A+ ++I+F VT  GLEDQLL  V+  E
Sbjct: 3676 KVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTE 3735

Query: 3557 RPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEI 3616
            + +LE+ + +L +     K  +KELED+LL RL++  G+ + D +L+  L  TK TA E+
Sbjct: 3736 KQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEV 3795

Query: 3617 EEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAI 3676
             +K+  +  TEV+IN ARE YRP A R S+LYF++ ++  +N +YQ SL+ F  +F+ ++
Sbjct: 3796 TQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSL 3855

Query: 3677 QRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVEL 3736
             R+  +    +R+ N+ + +TY VY Y ARGL+E  K +F   +T ++   +  +   E 
Sbjct: 3856 ARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEF 3915

Query: 3737 DFLLR----FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVES 3792
              L++       KA    P  ++    W  +  LS++ +F ++   I  + K WK   + 
Sbjct: 3916 LTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWFDK 3975

Query: 3793 EAPEKEIFPKEW-KNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKS 3851
            E PE+E  P  + K+    ++L ++R   PDR     + ++ + MG K+ EG  ++  K+
Sbjct: 3976 ENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKT 4035

Query: 3852 YEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVA 3911
            +EES P T +  +LS G DP   + ALGK+L       +   VS+GQGQEV A   L   
Sbjct: 4036 WEESDPRTPLICLLSMGSDPTDSIIALGKRLKI-----ETRYVSMGQGQEVHARKLLQQT 4090

Query: 3912 AEKGHWVILQVRGGQHCRNIHLVARWLGTL-DKKLERYSTGSHEDYRVFISAEPAPSPET 3970
               G W +LQ        N HL   ++  L D  +E      H+ +R++++ E       
Sbjct: 4091 MANGGWALLQ--------NCHLGLDFMDELMDIIIETELV--HDAFRLWMTTEAHKQ--- 4137

Query: 3971 HIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAV 4030
               P  +L+ +IK  N+PP G+ A L +     +QD L++ +   ++K ML+A+ + H+ 
Sbjct: 4138 --FPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGS-QWKPMLYAVAFLHST 4194

Query: 4031 VAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLE---ANPKVPWDDLRYLFGEIMYGGH 4087
            V ERRKFGA GWN  Y FN  D   ++  + N+L+       V W  +RY+ GEI YGG 
Sbjct: 4195 VQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGR 4254

Query: 4088 ITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLY 4147
            +TDD+D+RL  T+   +    M   D     G+ IP       Y +YI      +SP ++
Sbjct: 4255 VTDDYDKRLLNTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVF 4314

Query: 4148 GLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLE 4207
            GLHPNA+I + +  ++ +  T+L +QPK+T  G     +RE     L             
Sbjct: 4315 GLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDE--TREAVVARLA------------ 4360

Query: 4208 LRRGGCPGTGFQVKAVLDDILEKIPET---FNMAEIMAKAAEKTPYVVVAFQECERMNIL 4264
                             DD+LEK+P     F + E + K     P  +   QE +RM  +
Sbjct: 4361 -----------------DDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRV 4403

Query: 4265 TNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLL 4324
             + +R +L EL L + G + ++ ++ D    +F   +P  W   ++ S   L  W+ +L+
Sbjct: 4404 LSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWISST-LGFWFTELI 4462

Query: 4325 LRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNE-WPLDKMCLSVEVTKKN 4383
             R  +  +W  +   P   W+ GFFNPQ FLTA+ Q + R N+ W LD M L  EVTK  
Sbjct: 4463 ERNSQFTSWVFN-GRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWM 4521

Query: 4384 REDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKN 4443
            ++D++APP EG YVYGL++EGA WD +   + E++ K L   MPVI I A   + +    
Sbjct: 4522 KDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIYA-ENNTLRDPR 4580

Query: 4444 IYECPVYKTRIRGP-TYVWTFNLKTKEKAAKWILAAVALLLQV 4485
             Y CP+YK  +R    Y+   +L+T +    W+L  VALL  V
Sbjct: 4581 FYSCPIYKKPVRTDLNYIAAVDLRTAQTPEHWVLRGVALLCDV 4623



 Score =  168 bits (426), Expect = 1e-40
 Identities = 148/628 (23%), Positives = 282/628 (44%), Gaps = 50/628 (7%)

Query: 190 LHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQLNRPK 249
           L  IE  +  W  Q   VL++++ Q L +     P+ E E W  RL     + EQL  P 
Sbjct: 250 LGKIEDCMKVWIKQTEQVLAENN-QLLKEADDVGPRAELEHWKKRLSKFNYLLEQLKSPD 308

Query: 250 VNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQADFTMLPT 309
           V  ++ +L  AKS      + +   +T+   EA D V YL  L    + +  +D   +  
Sbjct: 309 VKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYSSDPLSMMD 368

Query: 310 FIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLS----------PEEVL 359
            I  +++ I  I++ S YYNT  +I  +  +  NQII   + +++          P++V+
Sbjct: 369 AIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYITNNGTASIWNQPQDVV 428

Query: 360 KGLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFK-DKEPVPWEFPSSLAFSRIN 418
           +      E++LS I        +L Q Y  C    K   K +     ++F     F +  
Sbjct: 429 E------EKILSAI--------KLKQEYQLCFHKTKQKLKQNPNAKQFDFSEMYIFGKFE 474

Query: 419 SFFQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDP 478
           +F +R+  I +++ T   +  L+   + G     L  + T+ Y  +   +K     +Y+ 
Sbjct: 475 TFHRRLAKIIDIFTTLKTYSVLQDSTIEG-----LEDMATK-YQGIVATIK---KKEYNF 525

Query: 479 LDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLIL 538
           LD    +FD+DY +F  +  DL   L       F   + I+++ + L M        +  
Sbjct: 526 LDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTF---AKIQNTNQALRMLKKFERLNIPN 582

Query: 539 AEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQER 598
             +  +Y ++LE + A++D    LY  Q         P + +N PP+AG++ W+ +L  R
Sbjct: 583 LGIDDKYQLILENYGADIDMISKLYTKQKYD------PPLARNQPPIAGKILWARQLFHR 636

Query: 599 LEVSMKHLKHVEHP-VMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLG 657
           ++  M+  +  +HP V+S AEAK   + Y+ M ++L       ++ W+  + ++ H  L 
Sbjct: 637 IQQPMQLFQ--QHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLRQI-EEIHVGLE 693

Query: 658 QPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNL 717
             L+++   +  + VNF   ++ + RE + +  Q   E+   A SLF + + +++   N+
Sbjct: 694 ASLLVKAPGTGELFVNFDPQILILFRETECM-AQMGLEVSPLATSLFQKRDRYKRNFSNM 752

Query: 718 ELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHN 777
           ++++  Y  +K+ + A    LI   L  +D  L      L W    +  Y++     + +
Sbjct: 753 KMMLAEYQRVKSKIPAAIEQLIVPHLAKVDEALQPGLAALTWTSLNIEAYLENTFAKIKD 812

Query: 778 LQNRMQKAKQNIE-GISQAMKDWSANPL 804
           L+  + +    IE  I   +++ S+ PL
Sbjct: 813 LELLLDRVNDLIEFRIDAILEEMSSTPL 840


>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
          Length = 4490

 Score = 1896 bits (4911), Expect = 0.0
 Identities = 1181/3618 (32%), Positives = 1906/3618 (52%), Gaps = 172/3618 (4%)

Query: 946  AKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNF 1005
            A+   N+   + ++ D+ ++   +SS V +  K A E    F++Y  LWT++    +K F
Sbjct: 966  ARKLKNFYPGVAEHKDISKLVLLLSSSVNSLRKAAHEALQDFQKYKTLWTEDRDVKVKEF 1025

Query: 1006 LIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCD 1065
            L                       P+L + + +I  Y    +E+ + +   V  G L+  
Sbjct: 1026 LANN--------------------PSLTEIRSEILHYATFEQEIDELKPIIVV-GALELH 1064

Query: 1066 CRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEV 1125
              P K AL    + W  +  R+L+      ++ + AF+      L++P++  D D +   
Sbjct: 1065 TEPMKLALSIEAKAWKMLLCRYLNEEYKKKMSYMIAFINEYLKKLSRPIR--DLDDVRFA 1122

Query: 1126 MGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQV 1185
            M  L  +++ +   D    P+++   +L  +  E+ +E    +  L   +   +  A+ V
Sbjct: 1123 MEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSFNKLQSKAVSV 1182

Query: 1186 KLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKVFLLKGIM 1245
            +  +  +Q    S L    + F      F E +  E P   + P P ++ N++ + +   
Sbjct: 1183 QEDLVQVQPKFKSNLLESVEVFREDVINFAEAYELEGPMVPNIP-PQEASNRLQIFQASF 1241

Query: 1246 EAL-------SKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWK 1298
            + L       S    LF +PV DY+ L    +E+ LL++L+ +   V +SI  +    W 
Sbjct: 1242 DDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWG 1301

Query: 1299 DINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERH 1358
            D+++E+++ +  +F    R L K +K W AF+ L   + +   S   +  + N A+++RH
Sbjct: 1302 DVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRH 1361

Query: 1359 WQQLMQATQVKFKM-SEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTW 1417
            W ++ + T   F + S+   L ++++  L  ++D++ +I   A+KE  +E  L  +   W
Sbjct: 1362 WDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENW 1421

Query: 1418 SMMEFQHEPHPRTGTMMLKSSEV--LVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKL 1475
            +            G ++LK +E   ++  +ED+ + L +L+ ++Y A F K + +W  KL
Sbjct: 1422 TNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKL 1481

Query: 1476 STADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPN 1535
            ST+  +I  W  VQ  W +LE++F+G  DI  QLP +++RF +I++ +  +M+ A + PN
Sbjct: 1482 STSSDIIEEWLVVQNLWVYLEAVFVGG-DIAKQLPQEAKRFQNIDKSWIKIMQRAHENPN 1540

Query: 1536 VVEA-TSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGND 1594
            V+        +   L  L + L +C+K+L  YLE KRL FPRF+FVS   LL+IL   +D
Sbjct: 1541 VINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASD 1600

Query: 1595 PVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLN 1654
               +  HL  + D++ ++ F     D+ + V     S+E E +V D      G VE+WL 
Sbjct: 1601 SHTIQPHLPAVSDNINEVTFHAKDYDRIMAV----ISREGEKIVLDNSVMAKGPVEIWLL 1656

Query: 1655 RVLDRMCSTLRHEIPEAVVTYEEKPRE--QWILDYPAQIWWTTEVGLAFARLEEGYENAI 1712
             +L    S+L + I  A     +   +   ++  +PAQ+       L     EE   NA 
Sbjct: 1657 DLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGIQMLWTHDSEEALRNAK 1716

Query: 1713 KDY------NKKQISQLNVLITLLIGNLNAGDRMKIMTICTIDVHARDV---VAKMIVES 1763
             D       N+K +  LN LI+    +L+  DR+K  T+ TI VH RD+   + KM ++S
Sbjct: 1717 DDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIHVHQRDIFDDLVKMHIKS 1776

Query: 1764 SQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSL 1823
               F W  Q R  + E+      +I D    Y  E+LG T RLVITPLTDRCYITL Q+L
Sbjct: 1777 PTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFLGCTDRLVITPLTDRCYITLAQAL 1836

Query: 1824 HLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGC 1883
             + MGGAPAGPAGTGKTETTKD+GR LG  V VFNCS+QMD++  G I+KGLAQ+G+WGC
Sbjct: 1837 GMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGC 1896

Query: 1884 FDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFL-GEIIGLIPTVGIFITMNPGYAGR 1942
            FDEFNRI + VLSV A Q+  V  A + +KK F F  G+ + L P  GIF+TMNPGYAGR
Sbjct: 1897 FDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGR 1956

Query: 1943 AELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDH 2002
             ELPENLK  FR  AM+VPD ++I  + L + GFLE  +LA+KF  LY LC+E L+KQ H
Sbjct: 1957 QELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVH 2016

Query: 2003 YDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFP 2062
            YD+GLR I SVL   GS KR  P  +E  ++MR LRD N+ K+V +D P+F+ LI DLFP
Sbjct: 2017 YDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFP 2076

Query: 2063 ALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQ 2122
             L +        +  +   +    L     + LK+VQL E   VRH +  +G +GSGK+ 
Sbjct: 2077 GLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTT 2136

Query: 2123 VLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHD 2182
            V+  L K      R    + ++PKA+T  ++FG ++  T +W DG+FST+ R        
Sbjct: 2137 VITILMKAQTECGRPHREMRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKG 2196

Query: 2183 GPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATV 2242
               ++ILDG +D +WIE+LN+V+DDNK LTLA+ +RIP+  + +L+FE+ ++  A+PATV
Sbjct: 2197 ENIFLILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATV 2256

Query: 2243 SRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPV 2302
            SR G++YI+ + L W P++ +W+++R  Q E A  + L++K        ++        +
Sbjct: 2257 SRMGMVYISSSALSWRPILQAWLKKRTAQ-EAAVFLTLYEKVFEDTYTYMKLNLNPKMQL 2315

Query: 2303 PEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFS 2362
             E   I   L LLE L+  K     S  E     FVF   W+ G A+ + +  +    F 
Sbjct: 2316 LECNYIVQSLNLLEGLIPSKEEGGVSCVEHLHKLFVFGLMWSLG-ALLELESREKLEAFL 2374

Query: 2363 KWWINEFKTIKFP--SQGTIFDYYIDPDTKKFLPWTDKVPSFELDPD-VPLQAS-LVHTT 2418
            +   ++    + P  S  T++++Y+  D   +  W  K+  +    D +P  +S LV   
Sbjct: 2375 RQHESKLDLPEIPKGSNQTMYEFYVT-DYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNV 2433

Query: 2419 ETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAM 2478
            + IR  + +D + ++   V+L G  GT K+V++   L+  + +  L +++ F+  T   M
Sbjct: 2434 DNIRTNFLIDTIAKQHKAVLLTGEQGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEPMM 2493

Query: 2479 LQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYD 2538
             Q  +E  ++K+ G  YGPPG +K+  FIDD+NMP ++++G    + ++RQ M+    Y 
Sbjct: 2494 FQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYS 2553

Query: 2539 RHK----LTLKDIHNCQYVACM-NPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTI 2593
              K     T+ D+   Q +A M +P  G   I  RL+R F VF  + P   ++  I+  I
Sbjct: 2554 LDKPGDFTTIVDV---QLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGII 2610

Query: 2594 LTQHL-AFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGL 2652
               +    RS    I  +   LV+    L Q      LPT  KFHY+FNLRDLS I+QG+
Sbjct: 2611 GCGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGM 2670

Query: 2653 LFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLF 2712
            L   AE   +   L+ L+ HE  RV  D+ +  +D++  +     + ++         + 
Sbjct: 2671 LTIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCIL 2730

Query: 2713 AKPNIFCHFAQGIGDPK---------YVP-VTDMAPLNKLLVDVLDSY----NEV--NAV 2756
             +P  F  F + + +P           VP + ++ P    L + L  Y    NE+     
Sbjct: 2731 PEP-YFVDFLREMPEPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTS 2789

Query: 2757 MNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKG 2816
            ++LV F+DA+ H+ +I+RI+ +  GNALLVGVGGSGKQSLSRLA++I+G  +FQITL + 
Sbjct: 2790 LDLVFFKDAMTHLIKISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRS 2849

Query: 2817 YGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEV 2876
            Y + +L  DL A Y  A        F+ TDS++ +E FL  +N+LL+SGEI  LF  DE+
Sbjct: 2850 YNVTNLTDDLKALYKVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEM 2909

Query: 2877 ENI----ISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFP 2932
            + I    IS M+ ++       T +  +++FI + R+ L V+LCFSPVG   R R+ KFP
Sbjct: 2910 DEITQGLISVMKRELPR--HPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFP 2967

Query: 2933 AVVNCTAIDWFHEWPEDALVSVSARFLEETEGI-PWEVKASISFFMSYVHTTVNEMSRVY 2991
             +++   +DWF  WP +AL++V++ FL +   +   E+K  +   M   H  V+E    Y
Sbjct: 2968 GLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESY 3027

Query: 2992 LATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAK 3051
                RR  + TPK++L  I  Y+N+ A+K   +  + ER+  GL KL   +  V  L   
Sbjct: 3028 FQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQD 3087

Query: 3052 LAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETD 3111
            LA++E EL   +  AD+++  V + A+  +K K    + + K + I   +  ++   E+ 
Sbjct: 3088 LAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESK 3147

Query: 3112 LAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMIL--------TAPGGK 3163
            L  A+PAL  A+ AL+T+  N++  ++    PP  ++ +   V++L        T    K
Sbjct: 3148 LEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEK 3207

Query: 3164 IPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTA 3223
                 SW  +  +M     FL SL++F K+ I E  ++  +PY     +  E  +     
Sbjct: 3208 SCCKPSWGESLKLMSATG-FLWSLQQFPKDTINEETVELLQPYFNMDDYTFESAKKVCGN 3266

Query: 3224 AAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLT 3283
             AGL SW + +  FY +  +V P +  L +    LA A  +L + +  + E  A L  + 
Sbjct: 3267 VAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQ 3326

Query: 3284 SAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVL 3343
            + F+ A  EK+    +AD   + +  A+ L+ GL+ E IRW +  + F++Q   L GD+L
Sbjct: 3327 AKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDIL 3386

Query: 3344 LISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQ 3403
            L + F+SY+G F + +RN L++  W   +   K  IP T  L+ +S+L D   +  W  Q
Sbjct: 3387 LCTGFLSYLGPFNQIFRNYLLKDQWEMELRARK--IPFTENLNLISMLVDPPTIGEWGLQ 3444

Query: 3404 GLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQ 3462
            GLP D +S +N  I+    R+PL++D Q QG  WIK+K + ++L+   L  K +   +E 
Sbjct: 3445 GLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRTHLED 3504

Query: 3463 AISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKY--IKIGDKEVEYHPKFRLILHTKYF 3520
            ++S G  LLIE+I E +DP LD +L +N IK G    +K+GDKE +    F+L + TK  
Sbjct: 3505 SLSLGRPLLIEDIHEELDPALDNVLEKNFIKSGTTFKVKVGDKECDIMDTFKLYITTKLP 3564

Query: 3521 NPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKE 3580
            NP + PE+ A+ ++I+F VT  GLE+QLL  V+  E+ +LE  +  L +     K  +KE
Sbjct: 3565 NPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNKRKMKE 3624

Query: 3581 LEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPA 3640
            LED+LL +LSA  G+ + D +L+  L TTK TA+E+ EK+  A  TE+KIN A+E +RPA
Sbjct: 3625 LEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQEEFRPA 3684

Query: 3641 AERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSV 3700
            A R S+LYF++ +++ +N +YQ SL  F  +F++++ R+  +   ++R+ N+ + +TY V
Sbjct: 3685 ATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEYLTYEV 3744

Query: 3701 YMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLR----FPFKAGVVSPVDFLQ 3756
            + Y+ RGL+E  K +F+  +T ++   +  +   E   L++       KA    P  ++ 
Sbjct: 3745 FTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKPYRWIL 3804

Query: 3757 HQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKT-ALQKLCM 3815
               W  +  LS++ +F  + + I  + K WK   + +APE+EI P  + +      KL +
Sbjct: 3805 DMTWLNLVELSKLPQFAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLL 3864

Query: 3816 VRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDV 3875
            +R   PDR  +  + ++ + +  K+ E   +   K++EES   T +   LS G DP   +
Sbjct: 3865 IRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMGSDPTNQI 3924

Query: 3876 EALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVA 3935
            +AL KKL       +   +S+GQGQEV A   + ++ ++G WV+LQ        N HL  
Sbjct: 3925 DALAKKLKL-----ECRTISMGQGQEVHARKLIQMSMQQGGWVLLQ--------NCHLGL 3971

Query: 3936 RWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHAN 3995
             ++  L + L   +  S + +RV+I+ EP         P  +L+ ++K TNEPP G+ A 
Sbjct: 3972 EFMEELLETLIT-TEASDDSFRVWITTEPHDR-----FPITLLQTSLKFTNEPPQGVRAG 4025

Query: 3996 LHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTI 4055
            L +      QD L++    M +K ML+ + + H+ V ERRKFG  GWN  Y FN+ D + 
Sbjct: 4026 LKRTFAGINQDLLDISNLPM-WKPMLYTVAFLHSTVQERRKFGPLGWNIPYEFNSADFSA 4084

Query: 4056 SINVLYNYLEA---NPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEG 4112
            S+  + N+L+       V W+ +RY+ GE+ YGG +TDD+D+RL   +   +   +M E 
Sbjct: 4085 SVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEP 4144

Query: 4113 DVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEM 4172
                  G++IP       Y EYI      ++P ++GLHPNA+I + + T+  +  T+  +
Sbjct: 4145 SFCFYTGYKIPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITNI 4204

Query: 4173 QPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIP 4232
            QPKE  SG G G +RE     L                              +D+L K+P
Sbjct: 4205 QPKE--SGGGVGETREAIVYRLS-----------------------------EDMLSKLP 4233

Query: 4233 ETFNMAEI---MAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDV 4289
              +   E+   + K        +   QE +RM  + + +R SL +L L ++G + ++ ++
Sbjct: 4234 PDYIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENL 4293

Query: 4290 EDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFF 4349
             D    ++   +P  W   ++ S   L  W+ +LL R  +   W  +   P   W+ GFF
Sbjct: 4294 RDALDNMYDARIPQLWKRVSWDSST-LGFWFTELLERNAQFSTWIFE-GRPNVFWMTGFF 4351

Query: 4350 NPQSFLTAIMQSMARKNE-WPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWD 4408
            NPQ FLTA+ Q + R ++ W LD + +  EV ++ +E++T+PP EG Y+YGL+M+GA WD
Sbjct: 4352 NPQGFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWD 4411

Query: 4409 TQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVY-KTRIRGPTYVWTFNLKT 4467
             + G + E+  K L   +PV+ I AI     +   +Y CP+Y K R    T++    L+T
Sbjct: 4412 RRNGKLMESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDLTFITVVYLRT 4471

Query: 4468 KEKAAKWILAAVALLLQV 4485
                  WIL  VALL  +
Sbjct: 4472 VLSPDHWILRGVALLCDI 4489



 Score =  163 bits (412), Expect = 4e-39
 Identities = 154/731 (21%), Positives = 308/731 (42%), Gaps = 46/731 (6%)

Query: 69  PQSLKSKGVYFIKTKSE-NINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSL------- 120
           P  LK   ++F++ +++  IN    +   L+  +  +    L+  + ++L+++       
Sbjct: 11  PDKLKGLCIFFVRCRNDVAINVKTIQEEALFTVLDASK--GLLNGIRDMLANIFLPAVLA 68

Query: 121 ------LNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGT 174
                 LNQS+       + +E I + +  L      + G +K KT+  +          
Sbjct: 69  TNNWGALNQSKQGESEKHIFTETINRYLSFLDGARISIEGTVKLKTIDNVNF------SK 122

Query: 175 LESMERIPSSLDNL-LLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDA 233
           L + E + ++  N   +H +E  ++ W  QI  VL  +S Q   +     P  E E W  
Sbjct: 123 LHTFEEVTAAASNSETVHQLEEVLMVWYKQIEQVLI-ESEQMRKEAGDSGPLTELEHWKR 181

Query: 234 RLLNLKCIHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLR 293
                  I EQ+  P    ++ +L  A S      +++   +T+   E+ D V YL  L 
Sbjct: 182 MSAKFNYIIEQIKGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLE 241

Query: 294 ILLEEMEQADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFL 353
            + + +   D   +   I  +++ I  I   S YYNT  R+  +  +  NQ++   + ++
Sbjct: 242 KVCQPLYNHDLVSMAHGIQNLINAIRMIHGVSRYYNTSERMTSLFIKVTNQMVTACKAYI 301

Query: 354 SPEEVLKGLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLA 413
           +   +      E   VL  I   + + KE   ++       KL  +      +E      
Sbjct: 302 TDGGLNHVWDQETPVVLKKIQDCIFLFKEYQASFH---KTRKLISESSGEKSFEVSEMYI 358

Query: 414 FSRINSFFQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFAD 473
           F +  +F +R++ I E+      +  L    + G+  +++      IY  V +       
Sbjct: 359 FGKFEAFCKRLEKITEMITVVQTYSTLSNSTIEGI--DIMAIKFRNIYQGVKKK------ 410

Query: 474 CKYDPLDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLME 533
            +YD LDP  + FD D+ DF  KI  L+ ++       F      + + +LL     L  
Sbjct: 411 -QYDILDPRRTEFDTDFLDFMTKINGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKL-N 468

Query: 534 RPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSL 593
            P +  E+      +L+ + AELD  K LY +Q       + P + +NMPP+AG++ W  
Sbjct: 469 IPCLGLEINHTIERILQYYVAELDATKKLYHSQK------DDPPLARNMPPIAGKILWVR 522

Query: 594 ELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCH 653
           +L  R+   + +       ++S  + K   ++Y+++  +L       +  W+  + Q  H
Sbjct: 523 QLYRRISEPINYF-FKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIREISQ-LH 580

Query: 654 FNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKF 713
           + L   L +R   +  + VNF   ++ V+RE K +  + + ++P+ A+ L       +  
Sbjct: 581 YALQATLFVRHPETGKLLVNFDPKILEVVRETKCM-IKMKLDVPEQAKRLLKLESKLKAD 639

Query: 714 VGNLELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVRE 773
              L+ ++ +Y+E+   V +V   L+  +++ ++  L    T L W+   +  + QEV  
Sbjct: 640 KLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEVEL 699

Query: 774 ILHNLQNRMQK 784
           +L      ++K
Sbjct: 700 VLDMFNQLLKK 710


>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
          Length = 4116

 Score = 1893 bits (4904), Expect = 0.0
 Identities = 1171/3414 (34%), Positives = 1805/3414 (52%), Gaps = 213/3414 (6%)

Query: 1200 LRRKCQQFELK---QHEFRERFRREAPFSFSDPNPY--------KSLNKVFLLKGIMEAL 1248
            L ++C +FEL+    H   E FR+    +  +            K+LN+ F      E +
Sbjct: 786  LIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNELSKNLNRAF---AEFELI 842

Query: 1249 SKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDID 1308
            +K   L E     Y  L+A  +     ++LW      +   E+W       +N EQ+  +
Sbjct: 843  NKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIAEE 902

Query: 1309 CKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRA----VSELQNPAIRERHWQQLMQ 1364
                 +    L K +    A   L   VK  I   +     +S   NP +++RHWQQ+ +
Sbjct: 903  IGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQISE 962

Query: 1365 ATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQH 1424
                + K +E T L+++L+     + +++  I   A KE  +EK L  +   W  + F  
Sbjct: 963  IVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTFSF 1022

Query: 1425 EPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISI 1484
              +  T T +L + + +   L+D+ ++ Q +  S ++     E   W++KL      +  
Sbjct: 1023 VKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNLDA 1082

Query: 1485 WFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPG 1544
            W + Q TW +LE IF  SEDI  Q+P + ++F  ++  +K+LM  AVK   ++ A  +P 
Sbjct: 1083 WLKCQATWLYLEPIF-SSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQPR 1141

Query: 1545 LYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSK 1604
            +  KL+     L   +K L +YLE KRL FPRF+F+S+ +LL+ILS   DP+ V  HL K
Sbjct: 1142 MAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLKK 1201

Query: 1605 LFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQE---CDLSGQVEVWLNRVLDRMC 1661
             F+ + KL+F  +     L++ +GM S E E + F Q+    +  G VE WL +V   M 
Sbjct: 1202 CFEGIAKLEFTDN-----LEI-VGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMML 1255

Query: 1662 STLRHEIPEAVVTYEEKPREQWILDYPAQ-------IWWTTEVGLAFARLEEGYENAIKD 1714
            +++R  I   +  Y + PR  W+L +P Q       I+WT EV  A A      EN + D
Sbjct: 1256 ASMREVIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQALA------ENTLLD 1309

Query: 1715 YNKKQISQLNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQA 1771
            + KK   Q+  ++ L+ G L++G R+ +  +  IDVHARDVVAK+    V     F W +
Sbjct: 1310 FLKKSNDQIAQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWIS 1369

Query: 1772 QLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAP 1831
            QLR+ W    +     I   +  Y YEYLGN+PRLVITPLTDRCY TL  +L L +GGAP
Sbjct: 1370 QLRYYW--VAKDVQVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAP 1427

Query: 1832 AGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRIS 1891
             GPAGTGKTETTKDL +AL     VFNCS+ +DYK+ G  +KGLAQ GAW CFDEFNRI 
Sbjct: 1428 EGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIE 1487

Query: 1892 VEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKA 1951
            VEVLSV+A Q+  +Q AI  K K F F G  + L PT  +FITMNPGYAGRAELP+NLKA
Sbjct: 1488 VEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKA 1547

Query: 1952 LFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIK 2011
            LFR  AM+VPD+ LI EI L + GFL++R LA+K +  Y LC E LS Q HYD+G+RA+K
Sbjct: 1548 LFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVK 1607

Query: 2012 SVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRD 2071
            SVL  AG+LK   P   E  +L+RAL D N+ K +  D+P+F G+I DLFP + +P+   
Sbjct: 1608 SVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDY 1667

Query: 2072 LNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTY 2131
              F K++  +I ++KLQ    F+ K++Q+ E++ VRH   IVG+   GK+   K L    
Sbjct: 1668 EVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAAL 1727

Query: 2132 QNL----KRKPVAVD---LDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGP 2184
             +L    + +  AV+   ++PKA+T  +L+G  + V+ EW DG+ +   R+ A+   D  
Sbjct: 1728 GDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSLSDDR 1787

Query: 2185 KWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSR 2244
            KWII DG +D +WIE++NTV+DDNK L L S E I +N  M L+FE + L  A+PATVSR
Sbjct: 1788 KWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSR 1847

Query: 2245 AGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFDKYL---PTCLDKLRFGFKKITP 2301
             G++Y+ P  LGW P+  S+++       K +  ++ D ++     CL+  R   K +  
Sbjct: 1848 CGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQ 1907

Query: 2302 VPEITVIQTILYLLECLLTEKTVPPDSPRELYE------------LYFVFTCFWAFGGAM 2349
               I +  +++ L   LL E     +   EL E              F+F+  W   G +
Sbjct: 1908 TSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTI 1967

Query: 2350 FQDQLVDYRVEFSKWWIN------EFKTIK------FPSQGTIFD-YYIDPDTKKFLPWT 2396
              D    + V F    +         K++K      FP +G+I+D Y+I   +  +  WT
Sbjct: 1968 NADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQASGHWETWT 2027

Query: 2397 DKVPSFE--LDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDK 2454
              +   E  +     +   ++ T ET R  +F+   ++   P++ VG  GTGKS +  + 
Sbjct: 2028 QYITKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNF 2087

Query: 2455 LESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPE 2514
            L  L  + YL   + F+  T++   Q ++   L+++    +GPP  KK V F+DD+NMP 
Sbjct: 2088 LLHLPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPA 2147

Query: 2515 VDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFT-IDSRLQRHF 2573
             + YG   P  L+RQ +DH +W+D+   T  DI +   V  M P  G    I  R  RH 
Sbjct: 2148 KEVYGAQPPIELLRQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHL 2207

Query: 2574 CVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTA 2633
             + +++    + LT I+++I+  H   +   +   R    LV A   +++     FLPT 
Sbjct: 2208 NIISINAFEDDILTKIFSSIVDWHFG-KGFDVMFLRYGKMLVQATKTIYRDAVENFLPTP 2266

Query: 2634 IKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHR 2693
             K HYVFNLRD S + QG+L      L+     +RLW+HE  RV+ D+++D++D++    
Sbjct: 2267 SKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFN 2326

Query: 2694 VTMASTKKFFDDLGDELLF------------AKPNIFCHFAQGIGDPK-YVPVTDMAPLN 2740
            +   +T   F    +++L              +   F  + +   D K Y  +TD+  L 
Sbjct: 2327 MVKETTSNCFKQTIEKVLIHLSPTGKIVDDNIRSLFFGDYFKPESDQKIYDEITDLKQLT 2386

Query: 2741 KLLVDVLDSYNEVN-AVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRL 2799
             ++   L+ +N ++ A M+LV+F  A+ HI RI R+L+  +G+ LLVG+GGSG+QS ++L
Sbjct: 2387 VVMEHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKL 2446

Query: 2800 AAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLIN 2859
            + +++  +++QI + K Y   D + DL    ++  V    +VFL  D+Q+ +E F+  IN
Sbjct: 2447 STFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDIN 2506

Query: 2860 DLLASGEIPGLFMEDEVENIISSMRPQVKSLG--MNDTRETCWKFFIEKVRRQLKVILCF 2917
             LL +G++P +F  DE  +I+  M+   ++ G  +  T  + + FFIE+V  ++   L  
Sbjct: 2507 MLLNTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVINKISFSLAM 2566

Query: 2918 SPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFM 2977
            SP+G   R R R FP+++NC  IDWF  WP DAL  V+ +FLE+ E +   ++  +    
Sbjct: 2567 SPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVE-LDDNIRVEVVSMC 2625

Query: 2978 SYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMK 3037
             Y   +V ++S  Y    RR+NY TP ++LE I  ++ LL  KR E+     R   GL K
Sbjct: 2626 KYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQK 2685

Query: 3038 LQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVI 3097
            L   ASQV  ++ +L   + +L   +E   +++  +  E  +   +K +   +E +  V 
Sbjct: 2686 LDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVA 2745

Query: 3098 NKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMIL 3157
                   +  CE DLA+A PAL AA  ALDTLN  +++ +KS  +PP  V  V  ++ I+
Sbjct: 2746 AAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIM 2805

Query: 3158 ----------TAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKP-Y 3206
                       +  GK+ +D  W  +K ++G +  FL+SLK +DK++IP   +K  +  +
Sbjct: 2806 KGMKPERKPDPSGSGKMIED-YWGVSKKILGDL-KFLESLKTYDKDNIPPLTMKRIRERF 2863

Query: 3207 QGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCD----VAPKRQALEEANAELAEAQ 3262
              +P F P  I++ S+A  GLC W    VR  EVY      VAPKR+ L EA  +LA   
Sbjct: 2864 INHPEFQPAVIKNVSSACEGLCKW----VRAMEVYDRVAKVVAPKRERLREAEGKLAAQM 2919

Query: 3263 EKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENI 3322
            +KL++ + ++  +   L  L   FE+   +K   ++  +  ++ ++ A +L+ GL  E  
Sbjct: 2920 QKLNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKD 2979

Query: 3323 RWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPIT 3382
            RW E+      +   L GDVLL S  V+Y+G FT  YR +   + W+    +  +P    
Sbjct: 2980 RWTEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQ-WLAECKDKVIP---- 3034

Query: 3383 NGLDPLSL---LTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIK 3439
             G    SL   L D   +  W   GLP D  S +N  I+ N+ RW L++D   Q  KWIK
Sbjct: 3035 -GFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIK 3093

Query: 3440 NKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKG--K 3496
            N  + ++L  I+    +Y+ ++E A+  G  +LIENIGE +D  ++P+L + T K+   +
Sbjct: 3094 NMEKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVE 3153

Query: 3497 YIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKE 3556
            Y+++G+  +EY   F+L + T+  NPHY PE+  +  L+NF++T  GL+DQLL  V AKE
Sbjct: 3154 YMRLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKE 3213

Query: 3557 RPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEI 3616
            +P+LE+ K  L     + K  LKE+ED +L  LS + GN L D   ++ L ++K  + EI
Sbjct: 3214 KPELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEI 3273

Query: 3617 EEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAI 3676
             EK   A +TE +I+E R  Y+P A  ++ ++F ++DL  I P+YQ+SL  F  ++  ++
Sbjct: 3274 SEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSL 3333

Query: 3677 QRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVEL 3736
              +T + E+  R+  + D  T S+Y    R LFE+DKL+F   +T  ++  KKE+     
Sbjct: 3334 THSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVW 3393

Query: 3737 DFLLRFPFKAGVVSP---VDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESE 3793
             FLL          P     +L  + W  I   S + +   L   +E +   WK + +S 
Sbjct: 3394 YFLLTGGIALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKLIYDSA 3453

Query: 3794 APEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYE 3853
             P +E  P  WK    L+K+ ++RCLRPD+M  A++ F+ E MG  ++E  + +   SY 
Sbjct: 3454 WPHEEQLPGSWKFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYN 3513

Query: 3854 ESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAE 3913
            +SS    + F+LSP  DP+  +      LG  +   +   +SLGQGQ  +A   ++ A +
Sbjct: 3514 DSSCCAPLIFVLSPSADPMAGLLKFADDLG--MGGTRTQTISLGQGQGPIAAKMINNAIK 3571

Query: 3914 KGHWVILQVRGGQHCRNIHLVARWLGTLDKKLER--YSTGSHEDYRVFISAEPAPSPETH 3971
             G WV+LQ        N HL A W+ TL+K  E       ++  +R+++++ P+      
Sbjct: 3572 DGTWVVLQ--------NCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEK---- 3619

Query: 3972 IIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTL------EMCTKEMEFKCMLFALC 4025
              P  IL+N IK+TNEPP G+ ANL   L  +  D +      + C K + ++ MLF LC
Sbjct: 3620 -FPVSILQNGIKMTNEPPKGLRANL---LRSYLNDPISDPVFFQSCAKAVMWQKMLFGLC 3675

Query: 4026 YFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYG 4085
            +FHAVV ERR FG  GWN  Y FN  DL IS+  +  +L    +VP+D L YL GE  YG
Sbjct: 3676 FFHAVVQERRNFGPLGWNIPYEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYG 3735

Query: 4086 GHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG--FQIPPNLDYKGYHEYIDENLP-PE 4142
            G +TDD DRRL  + L+ +   E+ E    LAPG  + IPP+  Y+ Y +Y+  NLP   
Sbjct: 3736 GRVTDDKDRRLLLSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSYQSYIDYL-RNLPITA 3794

Query: 4143 SPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERK 4202
             P ++GLH NA+I      + +LF  VL   P+++    G+G S +E             
Sbjct: 3795 HPEVFGLHENADITKDNQETNQLFEGVLLTLPRQS---GGSGKSPQE------------- 3838

Query: 4203 GEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMA--KAAEKTPYVVVAFQECER 4260
                             V+ +  DIL K+P  F++ E+M       +     V  QE  R
Sbjct: 3839 ----------------VVEELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIR 3882

Query: 4261 MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY 4320
             N LT  +RRSL  L   +KG++ +++++E++  ++    VP  W A++YPS+  L  + 
Sbjct: 3883 FNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYV 3942

Query: 4321 ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT 4380
            ADLL R+   + W  D   P   W++GF+  QSFLT + Q+ ARK   P+D +    EVT
Sbjct: 3943 ADLLARLTFFQEW-IDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVT 4001

Query: 4381 KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME 4440
             +    M   P +G+Y+ GLF+EGARWD +T  I E+  K L   +P+I++K        
Sbjct: 4002 PQETV-MENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFL 4060

Query: 4441 TKNIYECPVYKTRIRGPT---------YVWTFNLKTKEKAAKWILAAVALLLQV 4485
             ++IY CPVYKT  R  T         YV +  L T      WI   VA L Q+
Sbjct: 4061 HQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLCQL 4114


>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
          Length = 4646

 Score = 1344 bits (3478), Expect = 0.0
 Identities = 950/3423 (27%), Positives = 1677/3423 (48%), Gaps = 299/3423 (8%)

Query: 1263 KQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKE 1322
            ++++    E++ LK +W  +  V   I+  K   W  +   ++  +       ++S    
Sbjct: 1317 ERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPAR 1376

Query: 1323 MKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLADLL 1382
            ++ + ++  +   +K  +     V EL++ A+++RHW+QLM+   V + +SE  TL  + 
Sbjct: 1377 LRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSE-LTLGQIW 1435

Query: 1383 QLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLV 1442
             ++L   E  V++++  A  E  +E+ LK +   W+  E     + +    +++  + L 
Sbjct: 1436 DVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNY-QNKCRLIRGWDDLF 1494

Query: 1443 ETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGS 1502
              ++++   +  + +S Y   F ++  SW+ KL+   ++  +W +VQR W +LE IF GS
Sbjct: 1495 NKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGS 1554

Query: 1503 EDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKA 1562
             DI+  LP ++QRF  I+ EF ALM+   K+P V++  +  G+   LE L   L   +KA
Sbjct: 1555 ADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKA 1614

Query: 1563 LAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKP 1622
            L EYLE +R +FPRFYFV   DLL+I+ N  +  ++ +H  K+F  +  +    D S   
Sbjct: 1615 LGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNS--- 1671

Query: 1623 LKVGLGMYSKEDEYMVFDQECDLSGQVEV--WLNRVLDRMCSTLRHEIPEAV-------- 1672
              V LG+ S+E E ++F     ++   ++  WL  V   M  TL   + E+V        
Sbjct: 1672 --VVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGK 1729

Query: 1673 ---------VTYEEKPREQWILDYPAQIWWTTEVGLAFARLEEGYENAIKDYNKKQIS-Q 1722
                     +T+ +K + Q ++   AQI W+  V  A + +  G + A        +   
Sbjct: 1730 ATSIDPNTYITWIDKYQAQLVV-LSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVT 1788

Query: 1723 LNVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDE 1779
            LNVL   ++       R K+  + T  VH RDV   +I   ++++++F W +Q+R  +D 
Sbjct: 1789 LNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDP 1848

Query: 1780 EKRHCFANI----CDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPA 1835
            ++      +     +A+  Y +EYLG   +LV TPLTDRCY+T+TQ+L   +GG+P GPA
Sbjct: 1849 KQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPA 1908

Query: 1836 GTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVL 1895
            GTGKTE+ K LG  LG  V VFNC E  D+++ G I+ GL Q GAWGCFDEFNR+   +L
Sbjct: 1909 GTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERML 1968

Query: 1896 SVIAVQVKCVQDAIRAKKK----------AFNFLGEIIGLIPTVGIFITMNPGYAGRAEL 1945
            S ++ QV+C+Q+A+R                  L + + + P + IFITMNPGYAGR+ L
Sbjct: 1969 SAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNL 2028

Query: 1946 PENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDW 2005
            P+NLK LFR  AM  PD +LI ++ML ++GF  A +LA K +  + LC E LS Q HYD+
Sbjct: 2029 PDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDF 2088

Query: 2006 GLRAIKSVLVVAGSLKRGDPSRA---------------------EDQVLMRALRDFNIPK 2044
            GLRA+KSVLV AG++KR    +                      E ++L++++ +  +PK
Sbjct: 2089 GLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPK 2148

Query: 2045 IVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDS------FVLKVV 2098
            +V +D+P+   L+ D+FP +   R       + +K+   E+ L   D       +V KV+
Sbjct: 2149 LVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVL 2208

Query: 2099 QLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKR-KPVAVDLDPKAVTCDELFGII 2157
            QL ++ Q+ H + +VG +GSGKS   + L K  + L+  + VA  +DPKA++ D L+G +
Sbjct: 2209 QLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTL 2268

Query: 2158 NPVTREWKDGLFSTIMRDLANITH---DGPKWIILDGDIDPMWIESLNTVMDDNKVLTLA 2214
            +P TREW DGLF+ ++R + +         +WI+ DGD+DP W+E+LN+V+DDNK+LTL 
Sbjct: 2269 DPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLP 2328

Query: 2215 SNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRK----- 2269
            + ER+ L   +R++FE+  L+ AT ATVSR G+++ +   L  + + ++++ R +     
Sbjct: 2329 NGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLD 2388

Query: 2270 --------------------------VQSEKANLMILF--DKYLPTCLDKLRFGFKKITP 2301
                                      +Q + A +M  +     L T   +  F  + I  
Sbjct: 2389 EGEDEAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMD 2448

Query: 2302 VPEITVIQTILYLLE--C--LLTEKTVPPDSPRELYEL------YFVFTCFWAFGGAMFQ 2351
            +  +  + ++  +L   C  +       PD P ++ +L      Y V+   W+  G    
Sbjct: 2449 LTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSG---- 2504

Query: 2352 DQLVDYRVEFSKWWINEFKTIKFPSQGTI--FDYYIDPDTKKFLPWTDKVPSFELD---- 2405
            D  +  R E  ++ I    T+  P+   I   DY +   + ++ PW  KVP  E++    
Sbjct: 2505 DSRLKMRAELGEY-IRRITTVPLPTAPNIPIIDYEVSI-SGEWSPWQAKVPQIEVETHKV 2562

Query: 2406 --PDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNY 2463
              PDV     +V T +T+R    +   + +  P++L G  G+GK++ +   L +L     
Sbjct: 2563 AAPDV-----VVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPD--- 2614

Query: 2464 LVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGT--------KKLVYFIDDMNMPEV 2515
             ++ V  NF  +SA    +L K  +        P G         K LV F D++N+P++
Sbjct: 2615 -MEVVGLNF--SSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDM 2671

Query: 2516 DKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTS--GSFTIDSRLQRHF 2573
            DKYGT    + IRQ ++H  +Y     T   +   Q+V   NP +  G   +  R  RH 
Sbjct: 2672 DKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHV 2731

Query: 2574 CVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTA 2633
             V  V +PG  +LT IY T    + A   +  +++  +  L AA +  +      F    
Sbjct: 2732 PVVYVDYPGPASLTQIYGTF---NRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDT 2788

Query: 2634 IKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLD-LVRLWLHETERVYGDKMVDEKDQETLH 2692
             + HY+++ R+++   +G+  +   +   P++ L+R+W HE  R++ D++V+++++    
Sbjct: 2789 -QPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTD 2847

Query: 2693 RVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNE 2752
                    K F ++  E   ++P ++ ++        Y+PV D   L   +   L  + E
Sbjct: 2848 ENIDTVALKHFPNIDREKAMSRPILYSNWLS----KDYIPV-DQEELRDYVKARLKVFYE 2902

Query: 2753 VNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQIT 2812
                + LVLF + + H+ RI+RI   P+G+ LL+GV G+GK +LSR  A+++GL V+QI 
Sbjct: 2903 EELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIK 2962

Query: 2813 LKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFM 2872
            + + Y   D   DL     ++  KN    F+M +S V +  FL  +N LLA+GE+PGLF 
Sbjct: 2963 VHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFE 3022

Query: 2873 EDEVENIISSMRPQVKSLG-MNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKF 2931
             DE   +++  +   +  G M D+ E  +K+F  +V R L V+   +P    L+ RA   
Sbjct: 3023 GDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATS 3082

Query: 2932 PAVVNCTAIDWFHEWPEDALVSVSARF-----LEETEGI--------------PWEVKAS 2972
            PA+ N   ++WF +W  +AL  V   F     LE+   I              P   + +
Sbjct: 3083 PALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREA 3142

Query: 2973 ISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLE 3032
            I     +VH T+++ +        R    TP+ +L+ I  Y NL  +KR+EL  +   L 
Sbjct: 3143 IVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLN 3202

Query: 3033 NGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEV 3092
             GL K++ T  QV++L+  L I+  EL+ KN +A+  ++ +  + ++  K+K ++ + + 
Sbjct: 3203 VGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQE 3262

Query: 3093 KVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTA 3152
            ++    + + +KQ + + DL K EPA++ AQ A+ ++ K +L E++S  +PP AV     
Sbjct: 3263 QLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALE 3322

Query: 3153 AVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKP-YQGNPT 3211
            ++ +L    G+   D  WK  + ++ + + F+ ++  F  E I +A  +  K  Y  NP+
Sbjct: 3323 SICLLL---GESTTD--WKQIRSIIMR-ENFIPTIVNFSAEEISDAIREKMKKNYMSNPS 3376

Query: 3212 FDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNK 3271
            ++ E +   S A   +  W I  + + ++   V P R  L++   +  + Q+K + ++  
Sbjct: 3377 YNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQM 3436

Query: 3272 IAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENF 3331
            I +L A+++     +    +E    + +  A    +  +  L+  L++E  RW ++ E F
Sbjct: 3437 IRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETF 3496

Query: 3332 RSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLK-VPIPITNGLDPLSL 3390
            ++Q  T+ GD LL +AF++Y GYF ++ R  L    +  + H+L+   I     +     
Sbjct: 3497 KNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNL----FTTWSHHLQQANIQFRTDIARTEY 3552

Query: 3391 LTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIR 3450
            L++  +   W    LP+D + TENA +L    R+PLI+D   Q  ++I N+Y+      +
Sbjct: 3553 LSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDR----K 3608

Query: 3451 LGQKSYLDV-----IEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGK--YIKIGDK 3503
            + + S+LD      +E A+  G+ LL++++ E+ DPVL+P+L R   + G    I +GD+
Sbjct: 3609 ITRTSFLDDAFRKNLESALRFGNPLLVQDV-ESYDPVLNPVLNREVRRTGGRVLITLGDQ 3667

Query: 3504 EVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQL 3563
            +++  P F + L T+     + P++ ++ T +NF VTR  L+ Q L  V+  ERPD+++ 
Sbjct: 3668 DIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEK 3727

Query: 3564 KANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEA 3623
            +++L K Q EF++ L++LE SLL  L+   G  L D  ++  LE  K  A+E+  KV E 
Sbjct: 3728 RSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEET 3787

Query: 3624 KITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPAN 3683
             I   ++    + Y P +   S +YF +  L +I+ +YQ+SL+ F  ++   +       
Sbjct: 3788 DIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLK 3847

Query: 3684 EV---KQRVINLTDEITYSVYMYTARGLFERDKLIF---LAQVTFQVLSMKKELNPVELD 3737
             V    QR+  +T ++    +   ARG+  +D + F   LA++  +  ++ +     E  
Sbjct: 3848 GVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKG-TVGEPTYDAEFQ 3906

Query: 3738 FLLR---FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEA 3794
              LR       AG    +  L  +    +  LS +  FK+L + ++   +++   ++S +
Sbjct: 3907 HFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQAD-EQFGIWLDSSS 3965

Query: 3795 PEKEIFPKEWKNKT-------ALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVE 3847
            PE+ + P  W  +T       A+ +L +++  RPDR+      FV   +G  F+      
Sbjct: 3966 PEQTV-PYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQP 4024

Query: 3848 FSKSY---EESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEV-V 3903
               ++    E  P+T +     PG D    VE L  +      N ++ ++++G  +    
Sbjct: 4025 LDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAE-----QNTQITSIAIGSAEGFNQ 4079

Query: 3904 AENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAE 3963
            A+ A++ A + G WV+L        +N+HL   WL  L+KKL  +S   H  +R+F++ E
Sbjct: 4080 ADKAINTAVKSGRWVML--------KNVHLAPGWLMQLEKKL--HSLQPHACFRLFLTME 4129

Query: 3964 PAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFA 4023
              P      +P  +L        EPP G+ AN+ +     +     +C    E   + F 
Sbjct: 4130 INPK-----VPVNLLRAGRIFVFEPPPGVKANMLRTFS--SIPVSRICKSPNERARLYFL 4182

Query: 4024 LCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLE---------ANPKVPWDD 4074
            L +FHA++ ER ++   GW++ Y F   DL  + + +  +L+         +  K+PW  
Sbjct: 4183 LAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSA 4242

Query: 4075 LRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLA------PGFQIPPNLDY 4128
            L+ L  + +YGG + +++D+RL  T+L     T   + +  LA         Q+P  +  
Sbjct: 4243 LKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRR 4302

Query: 4129 KGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSRE 4188
            + + ++++     ++P   GL  NAE   LT     +   +L+MQ  E +          
Sbjct: 4303 EEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDED--------- 4353

Query: 4189 EKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKT 4248
                 L    +E+K    +    G P     +     + L  IP+T +  +   +   K 
Sbjct: 4354 ----DLAYAETEKKTR-TDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENI-KD 4407

Query: 4249 PYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVAR 4308
            P      +E +    L  ++R+ L ++    +G+   T  +  L   L    +P +W   
Sbjct: 4408 PLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHY 4467

Query: 4309 AYPSMMGLAAWYADLLLRIRELEAWTTDFALPTT-------VWLAGFFNPQSFLTAIMQS 4361
              P+ M +  W +D   RI++L+  +   A           V L G F P++++TA  Q 
Sbjct: 4468 TVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQY 4527

Query: 4362 MARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKE 4421
            +A+ N W L+++CL V VT      + A       V GL ++GA  +     ++ A    
Sbjct: 4528 VAQANSWSLEELCLEVNVTTSQGATLDAC---SFGVTGLKLQGATCNNNKLSLSNA---- 4580

Query: 4422 LTPAMPVIFIKAIPVDRMETK-NIYECPVYKTRIRGP-TYVWTFNLKTKEKAAKWILAAV 4479
            ++ A+P+  ++ +     E K ++   PVY    R    +   F + TKE    +    V
Sbjct: 4581 ISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGV 4640

Query: 4480 ALL 4482
            A+L
Sbjct: 4641 AVL 4643



 Score = 47.4 bits (111), Expect = 3e-04
 Identities = 116/640 (18%), Positives = 252/640 (39%), Gaps = 73/640 (11%)

Query: 186 DNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQL 245
           D   L+ +++ +  W  +I+ V   D   A    L      E  FW      L  I E+ 
Sbjct: 238 DPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQ-----EISFWLNLERALYRIQEKR 292

Query: 246 NRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLK--PLRILLEEMEQAD 303
             P+V   ++IL+  K  +     +  T + + L+  ND    +K  PL  LL   E   
Sbjct: 293 ESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATE--- 349

Query: 304 FTMLPTFIAKVLDTICFIWATSEYYNTPARII-VILQEFCNQIIEMTRTFLSPEEVLKGL 362
              +   +  +   +  I  T        R++  I ++  +Q++++    L   +++   
Sbjct: 350 LDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKV----LGTRKLMHVA 405

Query: 363 QGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFFQ 422
             E E+V+           E++QT+D     +++  +D      E    + + RIN   +
Sbjct: 406 YEEFEKVMVACF-------EVFQTWDDEYEKLQVLLRDIVKRKREENLKMVW-RINPAHR 457

Query: 423 RIQT-IEELYKTAIEFLKLEKIELGGVRGNLL-------GSLVTRIYDEVFELVKVFADC 474
           ++Q  ++++ K   +  +L  + +  +R  +        G +      +V E++   AD 
Sbjct: 458 KLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADA 517

Query: 475 --------------KYDPLDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKS 520
                         + D LD      +   A  +   + +DR    I  +  D     K+
Sbjct: 518 NAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKN 577

Query: 521 SAKLLYMCG---GLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPL 577
           + ++  +      L  RP I   +    + +++    ++++    +  Q   S+   +  
Sbjct: 578 ANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSH 637

Query: 578 IHKNMPPVAGQLKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLR--C 635
           + +++PPV+G + W+ ++  +L     ++K VE  +  G E  +  QK  +  +  R   
Sbjct: 638 V-RDLPPVSGSIIWAKQIDRQLTA---YMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKL 693

Query: 636 HREKIYQQWVAGVDQDCHFNLG--------QPLILRDAASNL--IHVNFSKALVAVLREV 685
           + ++I+  W   V Q    NLG        +   +R    N+  + VNF   ++ + +EV
Sbjct: 694 NTQEIFDDWARKVQQR---NLGVSGRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKEV 750

Query: 686 ---KYLNFQQQKEIPDSAESLFSENETFRKFVGNLELIVGWYNEIKTIVKAVEFLLIKSE 742
              K+L F+    I + A      N+ +   +  +E +  +    + + +     L+ + 
Sbjct: 751 RNLKWLGFRVPLAIVNKAH---QANQLYPFAISLIESVRTYERTCEKVEERNTISLLVAG 807

Query: 743 LEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQNRM 782
           L+     L++    L W    +  Y+Q + E + N Q ++
Sbjct: 808 LKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKV 847


>gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens]
          Length = 798

 Score = 1213 bits (3139), Expect = 0.0
 Identities = 575/835 (68%), Positives = 689/835 (82%), Gaps = 37/835 (4%)

Query: 3651 LNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFE 3710
            +NDL+KI+P+YQFSLKAF++VF+KA++R  P   +++RV NL D IT+SVY YT RGLFE
Sbjct: 1    MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60

Query: 3711 RDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMD 3770
             DKL +LAQ+TFQ+L M +E+N VELDFLLR P + G  SPV+FL HQ WG +K LS M+
Sbjct: 61   CDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVEFLSHQAWGAVKVLSSME 120

Query: 3771 EFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKN 3830
            EF NLD DIEGSAK WKK VESE PEKE  P+EWKNKTALQ+LCM+R +RPDRMTYA+++
Sbjct: 121  EFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTALQRLCMLRAMRPDRMTYALRD 180

Query: 3831 FVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGK 3890
            FVEEK+GSK+V GR+++F+ S+EES P+T +FFILSPGVDPLKDVE+ G+KLG+T +N  
Sbjct: 181  FVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQN 240

Query: 3891 LHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYST 3950
             HNVSLGQGQEVVAE ALD+AA+KGHWVILQ        NIHLVA+WL TL+KKLE +S 
Sbjct: 241  FHNVSLGQGQEVVAEAALDLAAKKGHWVILQ--------NIHLVAKWLSTLEKKLEEHSE 292

Query: 3951 GSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEM 4010
             SH ++RVF+SAEPAPSPE HIIPQGILEN+IKITNEPPTGMHANLHKALD FTQDTLEM
Sbjct: 293  NSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEM 352

Query: 4011 CTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKV 4070
            C++E EFK +LFALCYFHAVVAERRKFG QGWNRSYPFN GDLTIS+NVLYN+LEAN KV
Sbjct: 353  CSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKV 412

Query: 4071 PWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKG 4130
            P+DDLRYLFGEIMYGGHITDDWDRRLCRTYL E+IR EMLEG++ LAPGF +P N+DY G
Sbjct: 413  PYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPGFPLPGNMDYNG 472

Query: 4131 YHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEK 4190
            YH+YID  LPPESPYLYGLHPNAEIGFLT TSEKLFRTVLE+QP+++ +  G G +REEK
Sbjct: 473  YHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEK 532

Query: 4191 AGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPY 4250
                                         VKA+L++ILE++ + FN+ E+MAK  E+TPY
Sbjct: 533  -----------------------------VKALLEEILERVTDEFNIPELMAKVEERTPY 563

Query: 4251 VVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAY 4310
            +VVAFQEC RMNILT E++RSL+EL LGLKGELT+T+ +E+L  AL++D VP++W  RAY
Sbjct: 564  IVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAY 623

Query: 4311 PSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPL 4370
            PS  GLAAW+ DLL RI+ELEAWT DF +P+TVWL GFFNPQSFLTAIMQS ARKNEWPL
Sbjct: 624  PSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPL 683

Query: 4371 DKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIF 4430
            D+M L  ++TKKNRE+  +PPREG+Y++GLFMEGA WDTQ G+I EA+LK+LTP MPV+F
Sbjct: 684  DQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMF 743

Query: 4431 IKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV 4485
            IKAIP D+ + +++Y CPVYKT  RGPTYVWTFNLKTKE  +KW+LA VALLLQ+
Sbjct: 744  IKAIPADKQDCRSVYSCPVYKTSQRGPTYVWTFNLKTKENPSKWVLAGVALLLQI 798


>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
          Length = 4314

 Score = 1160 bits (3001), Expect = 0.0
 Identities = 949/3556 (26%), Positives = 1647/3556 (46%), Gaps = 284/3556 (7%)

Query: 1062 LQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDG 1121
            L  +C P K  +   I++   +    L   +   L +++ F+  A   LT  +     + 
Sbjct: 908  LNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLT--IMPQSVEE 965

Query: 1122 LVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKL 1181
            + +      K++ER+     +F+  +    LL+T      E I     +  +     +  
Sbjct: 966  IGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFELMMESH 1025

Query: 1182 AIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAP----FSFSDPNPYKSLNK 1237
             + +K  +  ++ N  S L+   Q+ E    +F+ R+ +  P          N      K
Sbjct: 1026 QLMIKDQIEVMKGNVKSRLQIYYQELE----KFKARWDQLKPGDDVIETGQHNTLDKSAK 1081

Query: 1238 VFLLKGI--------MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSI 1289
            +   K I         + L      F +  P++    +  +++    ++W          
Sbjct: 1082 LIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGF 1141

Query: 1290 -----EDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLR 1344
                 EDW T + K    E+  ++   +   +R +++            +  K VI  L+
Sbjct: 1142 QEMANEDWITFRTKTYLFEEFLMN---WHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILK 1198

Query: 1345 AVSELQNPAIRERHWQQLMQATQVKFKMSEETTL-ADLLQL--NLHSYEDEVRNIVDKAV 1401
             V   +   +   HW  L +   +    S E  L  DLL++   + +   +++++  +A 
Sbjct: 1199 YV---RGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQ 1255

Query: 1402 KESGMEKVLKALD-----STWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLM 1456
             E  + + L+ LD     + +++++++ +   RT   ++K  + +V  + DN+  LQ+L 
Sbjct: 1256 GEVTIREALRELDLWGVGAVFTLIDYE-DSQSRT-MKLIKDWKDIVNQVGDNRCLLQSLK 1313

Query: 1457 MSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRF 1516
             S Y   F  +V+ W++KL+  D  +     +QR W +LE IF      R  LP +  RF
Sbjct: 1314 DSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFG-----RGALPKEQTRF 1368

Query: 1517 DDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPR 1576
            + ++++F+++M D  K   V   T+  G+ N L  +   L  C+K+L E+LE KR AFPR
Sbjct: 1369 NRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPR 1428

Query: 1577 FYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEY 1636
            FYF+   DLL+IL    +P  +  HL KLF  +  + F     D+  K    M S E E 
Sbjct: 1429 FYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCF-----DEKSKHITAMKSLEGEV 1483

Query: 1637 MVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYPAQIWWTTE 1696
            + F  +  LS  VE WLN +   M  TL   + E V T            +P+QI    E
Sbjct: 1484 VPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAE 1543

Query: 1697 VGLAFARLEEGYENAIKDYNKKQISQLNVLITLLI------------GNLNAGD-RMKIM 1743
                  +  E  ENAIKD++  QI     L+  L             GN  +G   +K+ 
Sbjct: 1544 Q----IKFTEDVENAIKDHSLHQIE--TQLVNKLEQYTNIDTSSEDPGNTESGILELKLK 1597

Query: 1744 TICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYL 1800
             +    +H  DVV ++    V +++ + W+ QLR  + +    C   + D++ QY+YEY 
Sbjct: 1598 ALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRF-YMKSDHTCCVQMVDSEFQYTYEYQ 1656

Query: 1801 GNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCS 1860
            GN  +LV TPLTD+CY+TLTQ++ + +GG P GPAGTGKTE+ K LG  LG  V VFNC 
Sbjct: 1657 GNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCD 1716

Query: 1861 EQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLG 1920
            E +D KS G I+ GL + GAWGCFDEFNR+   VLS +++Q++ +QDA++  +     LG
Sbjct: 1717 EGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLG 1776

Query: 1921 EIIGLIPTVGIFITMNP---GYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFL 1977
            + + +    GIFITMNP   GY GR +LP+NLK LFRP AM  PD ELI E++L +EGF 
Sbjct: 1777 KEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFK 1836

Query: 1978 EARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSL-----KRGDPSRA-EDQ 2031
            +A++L+RK + ++ L +ELL+ Q HYDWGLRA+K+VL  +G+L     K G    A E  
Sbjct: 1837 DAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANESH 1896

Query: 2032 VLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAED 2091
            ++++ALR   + K    D   F  LI D+FP +++           +KQ   E   +   
Sbjct: 1897 IVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIP 1956

Query: 2092 SFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCD 2151
            + + K ++L E L  R  V IVG +G+GKS + + L        +      ++PKA+   
Sbjct: 1957 NQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKVVKQYTMNPKAMPRY 2016

Query: 2152 ELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVL 2211
            +L G I+  TREW DG+ +   R +     D   WII DGDIDP WIESLN+V+DDN++L
Sbjct: 2017 QLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLL 2076

Query: 2212 TLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQ 2271
            T+ S ERI     +  VFE   L  A+PAT+SR G+++++  +   N ++ SW+ R +  
Sbjct: 2077 TMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWL-RNQPA 2135

Query: 2272 SEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRE 2331
              + NL      Y       L++  K+   V E +++ T++  L  L           R+
Sbjct: 2136 EYRNNLENWIGDYFEKA---LQWVLKQNDYVVETSLVGTVMNGLSHL--------HGCRD 2184

Query: 2332 LYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKK 2391
              E  F+       GG +     +++  E   W          P      D Y D    +
Sbjct: 2185 HDE--FIINLIRGLGGNLNMKSRLEFTKEVFHWARESPPDFHKP-----MDTYYDSTRGR 2237

Query: 2392 FLPWTDKVPSFELDPDVP--LQASLVHTTETIR-IRYFMD-LLMEKSWPVMLVGNAGTGK 2447
               +  K P      D    L   ++ T +  R + YF   L  +   P +LVG  G GK
Sbjct: 2238 LATYVLKKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLSSDTKQPFILVGPEGCGK 2297

Query: 2448 SVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKP---LEKKSGRNYGPPGTKKLV 2504
             +L+      L +    +  V  +  TTS  L   L +    +   +GR Y P   ++LV
Sbjct: 2298 GMLLRYAFSQLRSTQ--IATVHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLV 2355

Query: 2505 YFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTS--GS 2562
             ++ D+N+P++DK+GT      ++Q + ++ +YD + L    + N Q VA M+     G 
Sbjct: 2356 LYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDEN-LEWVGLENIQIVASMSAGGRLGR 2414

Query: 2563 FTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQ---LVAAAL 2619
              + +R      + ++ +P +E L TIY   L   L     + +I   SS+   L  + +
Sbjct: 2415 HKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSSSKIYLLAGSMV 2474

Query: 2620 ALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAE--VLKTPLDLV-RLWLHETER 2676
             +++++ A F       HY F    L+    GL     E      PLD V  +  +E  R
Sbjct: 2475 QVYEQVRAKFTVDDYS-HYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARR 2533

Query: 2677 VYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFC------HFAQGIGDPKY 2730
            ++ DK+V  K+   LH   +  T  F  D G ++L    + F       H +     P  
Sbjct: 2534 LFRDKIVGAKE---LHLFDIILTSVFQGDWGSDILDNMSDSFYVTWGARHNSGARAAPGQ 2590

Query: 2731 VPVTDMAPLNKL----LVDVLDS----YNEVNAVMNLVLFEDAVAHICRINRILESPRGN 2782
                   PL KL    L DV+      Y   N  ++++LF + + ++ RI+R+L  P G+
Sbjct: 2591 PLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQNLDILLFHEVLEYMSRIDRVLSFPGGS 2650

Query: 2783 ALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVF 2842
             LL G  G G+++++ L +++ G  +F   + +GY +   K DL      A ++    V 
Sbjct: 2651 LLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVL 2710

Query: 2843 LMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKF 2902
            L+ D Q     FL +IN LL+SGE+PGL+  +E+E ++  ++ Q    G        + +
Sbjct: 2711 LLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFG---PVFNY 2767

Query: 2903 FIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEET 2962
            F  ++++ L ++L      S   +     PA+     + W   W   ++  +      ET
Sbjct: 2768 FTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSET 2827

Query: 2963 EG---------IPWEVKASI--SFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIK 3011
             G            + K S+   F  S++   ++E  + Y AT  RY      TFL    
Sbjct: 2828 GGGEKYNDKKRKEEKKKNSVDPDFLKSFL--LIHESCKAYGATPSRY-----MTFLH--- 2877

Query: 3012 LYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQ 3071
            +Y  + + K+ EL+ +   L+ G+ KL    + VD+L  K   Q   LK K + AD  +Q
Sbjct: 2878 VYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQ 2937

Query: 3072 VVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNK 3131
            ++ +  +  S++K   ++ + ++      + E++   + +L + +P +  A+ A+  +  
Sbjct: 2938 MITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKP 2997

Query: 3132 NNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFD 3191
             +L+E++S   PPD + ++   V+ L         D SW + K  + K     + +  FD
Sbjct: 2998 ESLSEIRSLRMPPDVIRDILEGVLRLMG-----IFDTSWVSMKSFLAKRGV-REDIATFD 3051

Query: 3192 KEHIPEACLKAFKP--YQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQ 3249
              +I +   ++ +   ++   +FDP+  +  STAAA L +W    +++  V   + P   
Sbjct: 3052 ARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLET 3111

Query: 3250 ALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILL 3309
                  + L + +++  +++  +  +   +S L   F+  T+E  K + E       I  
Sbjct: 3112 EQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKA 3171

Query: 3310 ANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWI 3369
            A  L+  L  E+ RW   V     +  TL     L +AF++Y+    +  R   +E+ W 
Sbjct: 3172 AEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEE-WT 3230

Query: 3370 PYIHNLKVPIPITNGLDPLSL---LTDDADVATWNNQGLPSDRMSTENATI---LGNTER 3423
                        + GL+   L   L  +++   W ++GLPSD +S ENA +   +   + 
Sbjct: 3231 K-----------SAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQIIGLKS 3279

Query: 3424 W----PLIVDAQLQGIKWIKNKYR-SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGET 3478
            W    P ++D   Q  +W+K   + S L+ I     +++  +E A+  G TL+I+ + + 
Sbjct: 3280 WSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTLIIQEM-DG 3338

Query: 3479 VDPVLDPLLGRNTIKKGK--YIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLIN 3536
            V+PVL PLL R+ + +G    ++IGDK ++Y+ +FRL L T+  NP   P+  +  T +N
Sbjct: 3339 VEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVN 3398

Query: 3537 FLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNF 3596
            F  TR GL  QLLA  +  E+PDLE+ K  L + + + KI L +LE+SLL  L+ + GN 
Sbjct: 3399 FTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNI 3458

Query: 3597 LGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNK 3656
            L +  L+E+L  TK +++ I+E + E+   ++ +++ R+ Y P AE AS +YFI++DL+K
Sbjct: 3459 LENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSK 3518

Query: 3657 INPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIF 3716
            IN +Y+FSL AF  +F++A+Q    +   +QR+ +L   + + VY Y  R LF+ D+L+F
Sbjct: 3519 INNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMF 3578

Query: 3717 LAQVT-------FQVLSMKKELNPVELDFLLRFPFKAGVVS--PVDFLQHQGWG-GIKAL 3766
                        FQ          V  D L +   +  +    P    Q + W      +
Sbjct: 3579 ALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKI 3638

Query: 3767 SEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTAL-QKLCMVRCLRPDRMT 3825
            +    ++ L  +    A  W+    +   E+E FP     K +L Q++ +V+ LRPDR+ 
Sbjct: 3639 ALPSLYQTLCFE---DAALWRTYYNNSMCEQE-FPSILAKKVSLFQQILVVQALRPDRLQ 3694

Query: 3826 YAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFT 3885
             A+  F  + +G K V    +   + Y+E+     I  I+SPG DP ++++ L       
Sbjct: 3695 SAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQELANA---E 3751

Query: 3886 IDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKL 3945
                  H V++GQGQ  +A   L   A  G W+ L        +N+HLV  WL  L+K+L
Sbjct: 3752 RSGECYHQVAMGQGQADLAIQMLKECARNGDWLCL--------KNLHLVVSWLPVLEKEL 3803

Query: 3946 ERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQ 4005
               +    + +R++++AE  P+         +L++++KIT E P G+  NL +  + +T 
Sbjct: 3804 N--TLQPKDTFRLWLTAEVHPN-----FTPILLQSSLKITYESPPGLKKNLMRTYESWTP 3856

Query: 4006 DTLEMCTKEMEFKC-MLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYL 4064
            +  ++  K+   +   LF+L +FHA   ERR +  QGW + Y F+  DL    N++    
Sbjct: 3857 E--QISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLF 3914

Query: 4065 EANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLE------GDVLLAP 4118
            +    V W+ +  L    +YGG I + +D R+ ++YL ++  + +++         +   
Sbjct: 3915 DGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPY 3974

Query: 4119 GFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETD 4178
               +P +     Y   I++    + P  +GL  N     +  +S+++  + +  Q +   
Sbjct: 3975 SVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPAN-----IARSSQRMISSQVISQLRILG 4029

Query: 4179 SGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMA 4238
                 G   + +  S +L P                         + ++ +K+ +  N+ 
Sbjct: 4030 RSITAGSKFDREIWSNELSP-------------------------VLNLWKKLNQNSNLI 4064

Query: 4239 -EIMAKAAEKTPYVVVAFQECERMNI--LTNEMRRSLKELNLGLKGELTITTDVEDLSTA 4295
             + +    ++    +++F   E+ N   L   + +SL  L+  ++G   ++++V+ L++A
Sbjct: 4065 HQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASA 4124

Query: 4296 LFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWT----TDFALPTTVWLAGFFNP 4351
            L     P  W ++ +        +   L+ R   ++ W         L  T+ L+  F+P
Sbjct: 4125 LLNQKCPLAWQSK-WEGPEDPLQYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHP 4183

Query: 4352 QSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQT 4411
             +FL A+ Q  AR     +D +        + +E      +    + GL +EG  +D   
Sbjct: 4184 DTFLNALRQETARAVGRSVDSLKFVASWKGRLQE-----AKLQIKISGLLLEGCSFDGNQ 4238

Query: 4412 GVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYEC---PVYKTRIRGPTYVWTFNLKTK 4468
                +     ++  +P  F+  IP D     +  EC   PVY T       V   ++   
Sbjct: 4239 LSENQLDSPSVSSVLP-CFMGWIPQDACGPYSPDECISLPVY-TSAERDRVVTNIDVPCG 4296

Query: 4469 EKAAKWILAAVALLLQ 4484
                +WI    AL L+
Sbjct: 4297 GNQDQWIQCGAALFLK 4312



 Score = 40.8 bits (94), Expect = 0.031
 Identities = 51/273 (18%), Positives = 119/273 (43%), Gaps = 24/273 (8%)

Query: 531 LMERPLILAEVA-PRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQL 589
           L++RP I  E+   R +++  L D+  D      +       + + PL  KN+  V   +
Sbjct: 427 LVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSGKNLSEVVNSI 486

Query: 590 KWSLELQERLEVSMKHLKHVEHPVMSGAEA-KLTYQKYDEMMELLRCHREKIYQQWVAGV 648
            W  +L+ +++ ++K    +   ++S     +  +Q   ++++ L+ + ++ +  W   +
Sbjct: 487 VWVRQLELKVDDTIK----IAEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSRDI 542

Query: 649 DQDCH-------FNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAE 701
                             ++  D+   L+ V++S  LV +LREV+ L+      IP   +
Sbjct: 543 QSGLSDSRSGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLS-ALGFVIPAKIQ 601

Query: 702 SLFSENETFRKFVGNLELIVGWYNEI-KTIVKAVEFLLIKSELEAIDVKLLS-----AET 755
            + +  + F K    L+ +  +YN I + ++++   ++++S L    +   S      ++
Sbjct: 602 QVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKS 661

Query: 756 TLFWNG----EGVFQYIQEVREILHNLQNRMQK 784
            + W+     EG  Q +Q   E L     +++K
Sbjct: 662 QITWDNPKELEGYIQKLQNAAERLATENRKLRK 694


>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
          Length = 3092

 Score =  954 bits (2467), Expect = 0.0
 Identities = 655/2072 (31%), Positives = 1037/2072 (50%), Gaps = 210/2072 (10%)

Query: 892  DESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDRMN 951
            D+   P+F+I +  D+D + F PT +   D   L+L+E +   + NV  +   L+     
Sbjct: 319  DQQRLPIFKIELTFDDDKMEFYPTFQDLEDN-VLSLVERIAEALQNVQTIPSWLSGTSTP 377

Query: 952  YKMDLEDNTDLIEMREEVSSLVINAMKEA--EEYQDSFERYSYLWTDNLQEFMKNFLIYG 1009
              +D E    ++    +     ++   E   + Y+   E+Y             N+L+ G
Sbjct: 378  VNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKY-------------NWLLDG 424

Query: 1010 CAVTAEDLDTW-TDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRP 1068
             AV  E+++T+ T+D       T  ++ E I+ +  L  E+       + +  ++ DC  
Sbjct: 425  TAV--ENIETFQTEDH------TFDEYTEFIEKFLSLASEIMLLPQW-IHYTMVRLDCED 475

Query: 1069 FKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGH 1128
             K  L +  + +        +N + N +A              + +KE           H
Sbjct: 476  LKTGLTNKAKAF--------ANILLNDIASKYRKENECICSEFEAIKE-----------H 516

Query: 1129 LMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWAN--------TKK 1180
             +KV E    T+ M + L   +E  +T G E   E+ L++QE     +          + 
Sbjct: 517  ALKVPE---TTEEMMD-LISYVEKARTVGIE---ELILRIQESKRQMSYFLDVFLFPQED 569

Query: 1181 LAIQVKLTVAPLQANEV----------------SILRRKCQQFELKQHEFRERFRREAPF 1224
            LA+   + + P + N +                + L  K ++  L+  +   R      F
Sbjct: 570  LALNATVLMWPRKINPIFDENDELIENAKHKKENELMAKREKLILEIEKESRRMEEFTEF 629

Query: 1225 SFSDPNPYKSLNKVFLLKGIMEA------LSKSGGLFEVPVPDYKQLKACHREVRLLKEL 1278
            +  +       +   L K I E+      ++K   LF+  +  Y +L      +   ++ 
Sbjct: 630  AELERMQQYVTDVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKF 689

Query: 1279 WDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKN 1338
            ++ V+    S + W    + D+N E M+ D ++F+   R + K +K +   +  +   K 
Sbjct: 690  FNFVLKWQRSEKRWMDGGFLDLNGESMEADVEEFS---REIFKTLKFFQTKLKKELQEKR 746

Query: 1339 VITSLRAVSELQ-------NPAI-----RERHWQQLMQATQVKFKMSEETTLADLLQLNL 1386
                 R++ E +       N  I     R RHW+Q+ +           TTL  +L+LNL
Sbjct: 747  KAARKRSLEEEKIEEEPKDNATITMCRMRARHWKQISEIVGYDLTPDSGTTLRKVLKLNL 806

Query: 1387 HSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLE 1446
              Y ++   I   A KE  +EK +  +  TW  + F    +  TG  +L S + +   L+
Sbjct: 807  TPYLEQFEVISAGASKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSSVDEIQAILD 866

Query: 1447 DNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIR 1506
            D  ++ Q +  S ++  F  E+ +W+ +L      I  W +VQ  W +LE IF  SEDI 
Sbjct: 867  DQIIKTQTMRGSPFIKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFC-SEDIM 925

Query: 1507 TQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEY 1566
             Q+P + ++F  +++ ++ +M+   K P V+ ATS  GL  KL+   + L    K L  Y
Sbjct: 926  QQMPEEGRQFQTVDRHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAY 985

Query: 1567 LETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVG 1626
            LE KRL FPRF+F+S+ ++L+ILS   DP+ V  HL K F+ + KL+F  +   K     
Sbjct: 986  LEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFLPNLDIK----- 1040

Query: 1627 LGMYSKEDEYMVFDQECDLS---GQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQW 1683
              MYS E E +        S   G VE WL +V D M  ++   I  A + Y E  R  W
Sbjct: 1041 -AMYSSEGERVELIALISTSAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARRDW 1099

Query: 1684 ILDYPAQI-------WWTTEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNA 1736
            + ++P Q+       +WT+E     +   EG    +K Y K+  +QLN ++ L+ G L+ 
Sbjct: 1100 VREWPGQVVLCISQMFWTSETQEVISGGTEG----LKKYYKELQNQLNEIVELVRGKLSK 1155

Query: 1737 GDRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEEKRHCFANICDAQI 1793
              R  +  + TIDVHARDVV  MI   V     F W AQLR+ W+ E       I +  +
Sbjct: 1156 QTRTTLGALVTIDVHARDVVMDMIKMGVSHDTDFLWLAQLRYYWENENAR--VRIINCNV 1213

Query: 1794 QYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTM 1853
            +Y+YEYLGN+PRLVITPLTDRCY TL  + +L +GGAP GPAGTGKTETTKDL +AL   
Sbjct: 1214 KYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQ 1273

Query: 1854 VYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKK 1913
              VFNCS+ +DY + G  +KGLA +GAW CFDEFNRI +EVLSV+A Q+ C+Q AI+ K 
Sbjct: 1274 CVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKL 1333

Query: 1914 KAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMA 1973
              F F G  + L P   + ITMNPGYAGR+ELP+NLK LFR  AM+VP++ LI EI L +
Sbjct: 1334 VVFVFEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYS 1393

Query: 1974 EGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVL 2033
             GFL AR L+ K +  Y LC E LS Q HYD+G+RA+K+VLV AG+LK   P+  ED +L
Sbjct: 1394 YGFLNARPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILL 1453

Query: 2034 MRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSF 2093
            +R+++D N PK ++ D+P+F G+  DLFP + +P      F +   ++     LQ    F
Sbjct: 1454 LRSIKDVNEPKFLSHDIPLFNGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFF 1513

Query: 2094 VLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL-------KRKPVAVDLDPK 2146
            + K++Q  E++ VRH   +VG   + K++VL  L  T   +       + K +   ++PK
Sbjct: 1514 LEKIIQTYEMMIVRHGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPK 1573

Query: 2147 AVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMD 2206
            ++T  +LFG  +PV+ EW DG+ +   R+ A       KW++ DG ID +WIES+NTV+D
Sbjct: 1574 SITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLD 1633

Query: 2207 DNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIE 2266
            DNK L L S E I ++  M L+FE   L  A+PATVSR G++Y+ P+ LGW P+VSSW+ 
Sbjct: 1634 DNKKLCLMSGEIIQMSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLN 1693

Query: 2267 RRK----VQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTE- 2321
              K        +A L  LF   +P  L++ R    ++  +   T++  IL +L       
Sbjct: 1694 SLKGPLCEPEYQALLRGLFAWLIPPSLNQ-RVELFQLNYL-YTTIVSKILKILITFRISN 1751

Query: 2322 --KTVPPDSPRELYELY------FVFTCFWAFGGAMFQD--QLVDYRVEF---------- 2361
              K VP  +     + +      F+F+  W+ GG+   D  ++ D  +            
Sbjct: 1752 YFKYVPLKTQCTFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENP 1811

Query: 2362 -----SKWWINEFKTIKFPSQGTIFDYYIDPDTK-KFLPWTDKVPSFEL-DPDVPLQASL 2414
                  KW         F  +G ++DY  +   K +++ W + + +  L D  + +Q  +
Sbjct: 1812 VPDSVGKW------ECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKIQDII 1865

Query: 2415 VHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKL-ESLNTDNYLVQAVPFNFY 2473
            V T +TIR  + MDL +  + P++ VG  GTGKSV + DKL   L  D Y    +  +  
Sbjct: 1866 VPTMDTIRYTFLMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSAR 1925

Query: 2474 TTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDH 2533
            T++  +Q ++   L+K+    +GPP  KK + FIDDMNMP ++KYG   P  L+RQ  D 
Sbjct: 1926 TSANQVQNIIMARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDC 1985

Query: 2534 RHWY---DRHKLTLKDIHNCQYVACMNPTSGSFT-IDSRLQRHFCVFAVSFPGQEALTTI 2589
             HWY   D  K+TL DI   + +A M P  G    +  R  RHF + +++    E +  I
Sbjct: 1986 GHWYDLKDTSKITLVDI---ELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRI 2042

Query: 2590 YNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIF 2649
            +++I+  +L           I +Q+V   + ++++     LPT  K HY FNLRD S + 
Sbjct: 2043 FSSIVAFYLRTHEFPPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVI 2102

Query: 2650 QGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDE 2709
            +G L    + +     ++RL++HE  RV+ D+++++ D+  L ++T    K  F +    
Sbjct: 2103 RGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKE---- 2158

Query: 2710 LLFAKPNIFCHFAQGIG-----------------------DPKYVPVTDMAPLNKLLVDV 2746
               +  +IF H  +                          D  Y+ + ++   + ++   
Sbjct: 2159 ---SFHSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQC 2215

Query: 2747 LDSYNEVNAV-MNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISG 2805
            LD YN+ +   MNLV+F   + H+ RI R+L+   GNALLVG+GGSG+QSL+RLA  ++ 
Sbjct: 2216 LDEYNQTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAK 2275

Query: 2806 LDVFQITLKKGYGIPDLKIDLAAQYIKAAVKN 2837
            + +FQ  + K YG+ + + D+ + +I   V N
Sbjct: 2276 MHIFQPEISKSYGMNEWREDMKS-FIAVPVTN 2306



 Score =  427 bits (1097), Expect = e-118
 Identities = 273/824 (33%), Positives = 424/824 (51%), Gaps = 72/824 (8%)

Query: 3685 VKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLR--F 3742
            +++R+  L D  TY++Y    R LFE+DKL+F   +   +L  +KE+   EL FLL    
Sbjct: 2316 LEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLLTGGV 2375

Query: 3743 PFKAGVVSP-VDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFP 3801
              K+   +P   +LQ + W  I   SE   F+ L          W+++ +S+ P    FP
Sbjct: 2376 SLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPHNAKFP 2435

Query: 3802 KEW-KNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTS 3860
                KN   LQK+ ++RCLRPD++T AI N+V +K+G KFVE    + +KSY +S+ +  
Sbjct: 2436 APMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSNCTIP 2495

Query: 3861 IFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVIL 3920
            + F+LSPG DP+  +         ++   K   +SLGQGQ  +A   +  A E+G WV L
Sbjct: 2496 LIFVLSPGADPMASLLKFANDK--SMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWVCL 2553

Query: 3921 QVRGGQHCRNIHLVARWLGTLDKKLERYSTGS-HEDYRVFISAEPAPSPETHIIPQGILE 3979
            Q        N HL   W+  L+K  E +++ + +  +R+++++ P+        P  IL+
Sbjct: 2554 Q--------NCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSK-----FPVTILQ 2600

Query: 3980 NAIKITNEPPTGMHANLHKAL---DLFTQDTLEMCT-KEMEFKCMLFALCYFHAVVAERR 4035
            N +K+TNEPPTG+  NL ++     +   +  + C  KE+ ++ +LF +C+FHA+V ER+
Sbjct: 2601 NGVKMTNEPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERK 2660

Query: 4036 KFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRR 4095
            KFG  GWN  Y FN  DL ISI  L  ++     +P++ + YL GE  YGG +TDDWDRR
Sbjct: 2661 KFGPLGWNIPYGFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRR 2720

Query: 4096 LCRTYLAEYIRTEMLEG-DVLLAP--GFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPN 4152
            L  T LA++    ++E      +P   +  PP   Y+ Y E+I +    + P ++GLH N
Sbjct: 2721 LLLTMLADFYNLYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHEN 2780

Query: 4153 AEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGG 4212
             +I      ++ LF ++L  Q     +GA         +GS   +  E            
Sbjct: 2781 VDISKDLQQTKTLFESLLLTQGGSKQTGA---------SGSTDQILLE------------ 2819

Query: 4213 CPGTGFQVKAVLDDILEKIPETFNMAEIMAK--AAEKTPYVVVAFQECERMNILTNEMRR 4270
                      +  DIL K+P  F++   + K     +     V  QE ER N L   +R 
Sbjct: 2820 ----------ITKDILNKLPSDFDIEMALRKYPVRYEESMNTVLVQEMERFNNLIITIRN 2869

Query: 4271 SLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIREL 4330
            +L++L   +KG + + + +E LS +L    VP+ W  R+YPS+  L ++  D L R+  L
Sbjct: 2870 TLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFL 2929

Query: 4331 EAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAP 4390
            + W      P   WL+GFF  Q+FLT  MQ+ ARK   P+D +    EV   +  D +  
Sbjct: 2930 QDWYNS-GKPCVFWLSGFFFTQAFLTGAMQNYARKYTTPIDLLGYEFEVIPSDTSDTS-- 2986

Query: 4391 PREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVY 4450
            P +G Y++GL+++GARWD ++G++AE   K L   MP+I+IK     R+   + Y CP+Y
Sbjct: 2987 PEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLY 3046

Query: 4451 KTRIRGPT---------YVWTFNLKTKEKAAKWILAAVALLLQV 4485
            KT  R  T         +V    LKT +    WI   VALL Q+
Sbjct: 3047 KTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLCQL 3090


>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
            sapiens]
          Length = 4515

 Score =  701 bits (1810), Expect = 0.0
 Identities = 506/1918 (26%), Positives = 886/1918 (46%), Gaps = 266/1918 (13%)

Query: 2774 RILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKA 2833
            R+L     N   +G+ G GK++ + LA Y++   ++++ +       + K      +I A
Sbjct: 2653 RLLSRELENCFQIGIDGCGKKTCATLACYLTDNKLYRVPISHKCAYIEFKEVFKKVFIHA 2712

Query: 2834 AVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMN 2893
             +K  P+V ++ +  + ++ FL  +N +++SG IP LF   E+++I   +R   +  G  
Sbjct: 2713 GLKGKPTVLMVPNLNIEQDSFLEDLNYIISSGRIPDLFENVELDSIAMKIRYLTEQSGHM 2772

Query: 2894 DTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVS 2953
            D R++   FF +++ + L + +  SP G   R   R +P++++   IDW+  WPE+AL+ 
Sbjct: 2773 DNRQSLLSFFQKRIYKNLHIFVIMSPEGPSFRQNCRVYPSMISSCTIDWYERWPEEALLI 2832

Query: 2954 VSARFLEETEGIP--WEVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIK 3011
            V+  FL+E         +K  ++     +H ++ +++R Y     R+ YTTP ++L+ ++
Sbjct: 2833 VANSFLKEKVNFENRENLKEKLAPTCVQIHKSMKDLNRKYFEETGRFYYTTPNSYLQFME 2892

Query: 3012 LYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQ 3071
             + ++L  +  E+  K +R   GL  +    + V +++ +L I   +++QK +  + L++
Sbjct: 2893 TFAHILRAREEEMQTKRDRFHMGLSTILEATTLVTEMQEELLILGPQVEQKTKETETLME 2952

Query: 3072 VVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNK 3131
             +  +++ V K + +  Q+E  V    + V +  +    +L    PA   A  AL+ L+K
Sbjct: 2953 KLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQKTANELKSVLPAFDKAIVALNALDK 3012

Query: 3132 NNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFD 3191
             ++ EL+ +  PP  V+ V  AV IL      + K  +W  AK+++ +   FL  L   D
Sbjct: 3013 ADVAELRVYTRPPFLVLTVMNAVCIL------LQKKPNWATAKLLLSETG-FLKKLINLD 3065

Query: 3192 KEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQAL 3251
            K+ IP+      K     P F+P  I   S A   LC W I +  ++EV   V PK+  +
Sbjct: 3066 KDSIPDKVFVKLKKIVTLPDFNPHKISLVSVACCSLCQWVIALNNYHEVQKVVGPKQIQV 3125

Query: 3252 EEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLAN 3311
             EA   L  A+++L+  +  +  +  +L  L +A++   AEK          +R    A+
Sbjct: 3126 AEAQNVLKIARQRLAEKQRGLQLVEEHLLFLQAAYKDTVAEKQLLANRKTMASRRFQCAS 3185

Query: 3312 RLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPY 3371
             L+  L  E  RW E++    ++   + GD+LL +A + Y G  T ++R  ++ K+    
Sbjct: 3186 VLLTVLEDEKTRWQETINQIDNKLEGILGDILLSAACIVYSGILTPEFRQLIVNKWETFC 3245

Query: 3372 IHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQ 3431
            I N    I +++    + ++    +++ W+NQGLP  + S ENA ++ N ++WPL++D  
Sbjct: 3246 IEN---GISLSSKFSLIKVMAQKYEISRWHNQGLPHGQYSVENAILIKNGQQWPLLIDPH 3302

Query: 3432 LQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNT 3491
             Q  KWI+    S L+ + +   +Y   IE A+  G ++L++N+ ET+ P L  +L ++ 
Sbjct: 3303 RQAHKWIRQMEGSRLQKLSIEDSNYTKKIENAMKTGGSVLLQNLLETLAPGLKAILKKDI 3362

Query: 3492 I-KKGKY-IKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLL 3549
              KKG Y I++GD E EY+  FRL L T+  NPH+ P +    T+INF VT  GL+DQLL
Sbjct: 3363 YQKKGHYFIRVGDAEFEYNSNFRLYLSTEIDNPHFLPSVYNFVTMINFTVTFQGLQDQLL 3422

Query: 3550 AAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETT 3609
            + VV  E P LE  ++ L +S +   I L+ELE+  L  L  A G+ L D  +V+ L  +
Sbjct: 3423 STVVTHEVPHLEDQRSKLLESISLDAITLEELEEKTLNLLQKALGSILDDDKIVDTLRKS 3482

Query: 3610 KHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFN 3669
            K T++EI +++   K  E +I   R+NY P A R +LLYF++ DL +IN +YQFSL  F+
Sbjct: 3483 KMTSNEISKRIEATKKAESEIQAIRKNYLPIATRGALLYFLVADLTQINYMYQFSLDWFH 3542

Query: 3670 VVFEKAI-------------QRTTP------------------ANEVKQRVINLTDEITY 3698
             VF  ++             ++ +P                   N + + + +  D +T 
Sbjct: 3543 QVFVSSVVSKSKEQEHSFKREKVSPKEVHEFISISKEPNLENEKNLLDKHIKSAIDMLTK 3602

Query: 3699 SVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELD--FL----------------- 3739
            S++   +  LF  DKL F  ++   ++      N ++ D  FL                 
Sbjct: 3603 SIFKVVSSALFNEDKLCFSFRLCTVIMQNNANGNLIQDDIGFLPEEEWNIFLYSGILINI 3662

Query: 3740 --------LRFPFKAGVVSPVDFLQHQGWGGIKALS-EMDEFKNLDSDIEGSAKRWKKLV 3790
                    L   F+ G    + +L    W   + +S  ++ F  L   +  +  +W    
Sbjct: 3663 KSALSQSRLTSTFEIGESQHLQWLSDSRWRQCQYVSTHLEPFSLLCKSLLSNVSQWDTFK 3722

Query: 3791 ESEAP---------------EKEIFPKE------------------WKNKTALQKLCMVR 3817
             S+A                E+   P E                  W+  T+ Q+L +V+
Sbjct: 3723 NSKAVYSLISTPFSSENASLEENTKPPEETELLNENKETCNPINFPWEKLTSFQRLILVK 3782

Query: 3818 CLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEA 3877
             LRP+ +  +++ F+ EKMG+K+++   V    +Y+ S+  T +  I + G+D    +  
Sbjct: 3783 VLRPESLNNSVRKFITEKMGNKYLQRTGVNLKDAYKGSNARTPLILIQTHGIDLTNILLR 3842

Query: 3878 LGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEK-GHWVILQVRGGQHCRNIHLVAR 3936
              ++L  T  +  +  +SLG+ Q   AE+ +  A  K   WV LQ        N HL   
Sbjct: 3843 FAQELKGTTHHVTI--ISLGRDQAAKAEDLILKALTKTQQWVFLQ--------NCHLATS 3892

Query: 3937 WLGTLDKKLERYSTGS---HEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMH 3993
            ++  L   +E +++ +     ++R+++S++   S      P  +L+  +KI  E P G+ 
Sbjct: 3893 FMPRLCTIVESFNSPNVTIDPEFRLWLSSKSYSS-----FPIPVLKKGLKIAVESPQGLK 3947

Query: 3994 ANLHKALDL-----FTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPF 4048
            +NL +          T++  E       +K +LF+LC+F+AV+ ER+ +G  GWN +Y F
Sbjct: 3948 SNLLQTFGCTGSGEVTEEIFENPDCGQWWKKLLFSLCFFNAVINERKNYGILGWNIAYKF 4007

Query: 4049 NNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTE 4108
            N+ DL ++I VL N L   P + W  LRYL GE++YGG + D+WD+R  +T L ++   E
Sbjct: 4008 NSSDLGVAIKVLENSLRGQPSISWQALRYLIGEVIYGGRVIDNWDKRCLKTLLYKFCNPE 4067

Query: 4109 MLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRT 4168
            +L+ D      F    +   K Y   I      + P + G+HP A         EK    
Sbjct: 4068 VLKDD------FSFSRSASIKDYIHIIQSLPDDDLPEVLGIHPEAIRSCWETQGEKFIEN 4121

Query: 4169 VLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDIL 4228
            ++ MQPK T               +L + P + K E               V  +L D+L
Sbjct: 4122 LIAMQPKTT-------------TANLMIRPEQSKDE--------------LVMEILSDLL 4154

Query: 4229 EKIPETFNMAEIMA--------------------KAAEKTPY---VVVAF--QECERMNI 4263
            +++P T    EI                         +  P    V++ F  QE +R + 
Sbjct: 4155 KRLPLTVEKEEIAVGTPSTLKSMMSSSIWESLSKNLKDHDPLIHCVLLTFLKQEIKRFDK 4214

Query: 4264 LTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADL 4323
            L   + +SLK+L L +KGE+ +T ++E++  +     VP  W   AY S   L++W  DL
Sbjct: 4215 LLFVIHKSLKDLQLAIKGEIILTQELEEIFNSFLNMRVPTLWQKHAYRSCKPLSSWIDDL 4274

Query: 4324 LLRIRELEAWT------------------------------------TDF--ALPTTVWL 4345
            + R+     W                                      +F    P+  WL
Sbjct: 4275 IQRLNFFNTWAKVAYTAIQRRYMRFVTVWKQSIPSTSQKCKHPEDSENNFFEGFPSRYWL 4334

Query: 4346 AGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEV----TKKNREDMTAPPRE-------- 4393
              FF PQ+FL A++Q   R     +D +  +  V    T K+ +     P++        
Sbjct: 4335 PAFFFPQAFLAAVLQDYGRSRGIAVDALTFTHHVISNTTDKDEKFSVFMPKKLNIVRRAF 4394

Query: 4394 --------GSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKN-- 4443
                    G Y++GLF+EGARW+ +  ++ ++   E+    P I+     +   +T N  
Sbjct: 4395 KGSASSHTGVYIFGLFIEGARWNREQKILEDSLPLEMCCDFPDIYFLPTKIS-TKTPNAS 4453

Query: 4444 --------IYECPVYKTRIRG--------PT-YVWTFNLKTKEKAAKWILAAVALLLQ 4484
                     +ECPVY+T  R         PT ++ +  L TK+  + WI   VALL +
Sbjct: 4454 NQTDSELYAFECPVYQTPERSRILATTGLPTNFLTSVYLSTKKPPSHWITMRVALLCE 4511



 Score =  620 bits (1600), Expect = e-177
 Identities = 420/1383 (30%), Positives = 677/1383 (48%), Gaps = 219/1383 (15%)

Query: 1271 EVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFV 1330
            ++ L K+LW+       +  +W+ +  + I+VE +  +  K    +  L+K +   D   
Sbjct: 995  DLTLRKKLWEAQEEWKRASWEWRNSSLQSIDVESVQRNVSKLMHIISVLEKGLPKSDMVT 1054

Query: 1331 GLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYE 1390
             L   V      L  +  L NP ++ RHW+ L +       + +   + +LL L +  YE
Sbjct: 1055 HLKQVVTEFKQELPIIIALGNPCLKPRHWEALQEIIGKSVPLDKNCKVENLLALKMFQYE 1114

Query: 1391 DEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRT--GTMMLKSSEVLVETLEDN 1448
            +E+ ++   A  E+ +EK+L  +   W+        H        ++ S + +   LE++
Sbjct: 1115 NEINDMSTSATNEAALEKMLFKIIDFWNTTPLPLILHHTEIYSIFIIPSIDDISAQLEES 1174

Query: 1449 QVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQ 1508
            QV L  +  S ++      V  W Q L+     +  W   QR W +LE +F  SE IR Q
Sbjct: 1175 QVILATIKGSPHIGPIKDLVNEWDQNLTLFSYTLEEWMNCQRNWLYLEPVFHSSE-IRRQ 1233

Query: 1509 LPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLE 1568
            LP +++ F  +   +K +M       N ++ T+  G+   L+     L   +K+L +YLE
Sbjct: 1234 LPAETELFSQVISMWKKIMSKIQNKQNALQITTSAGVLEILQNCNIHLEHIKKSLEDYLE 1293

Query: 1569 TKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLK-FRLDASDKPLKVGL 1627
             KRL FPRFYF+S+A+LLDIL++  +P  V  HL K F+++ +L  ++ D     +K+  
Sbjct: 1294 VKRLIFPRFYFLSNAELLDILADSRNPESVQPHLVKCFENIKQLLIWKQDIGPPAVKM-- 1351

Query: 1628 GMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEEKPREQWILDY 1687
             + S E E +V  ++  +   VE WL  V   M   L+          +E+     IL +
Sbjct: 1352 -LISAEGEGLVLPKKIRVRSAVEQWLVNVEKSMFDVLK----------KERYIYNIILLF 1400

Query: 1688 PAQIWWTTEVGLAFARLEEGYENAIKDYNKKQISQLN---------VLITLLIGNLNAGD 1738
             +QI +  +   +F          +  Y+++++ +++         V   +++   N+  
Sbjct: 1401 QSQIMFYNDCVKSF----------VSSYSREKLEKVHAGLMCHLEEVADLVVLDTSNSRT 1450

Query: 1739 RMKIMTICTIDVHARDVVAKMIVES---SQAFTWQAQLRHRWDEEKRHCFANICDAQIQY 1795
            +  +  +  + VH RD+V  +++++   ++ F W   L+++W+E+++ C+ +  +A   Y
Sbjct: 1451 KAILGALLILYVHCRDIVINLLLKNIFNAEDFEWTRHLQYKWNEKQKLCYVSQGNASFTY 1510

Query: 1796 SYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVY 1855
             YEYLG T RLVITPLTDRC++TL ++LHL +GG PAGPAGTGKTET KDL ++LG    
Sbjct: 1511 GYEYLGCTSRLVITPLTDRCWLTLMEALHLNLGGCPAGPAGTGKTETVKDLAKSLGKHCV 1570

Query: 1856 VFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKA 1915
            VFNC E +DYK     + GL Q+GAW CFDEFN I +EVLSVIA Q+  ++ A       
Sbjct: 1571 VFNCFEDLDYKIVRKFFFGLVQSGAWSCFDEFNLIDLEVLSVIASQILTIKAAKDNYSAR 1630

Query: 1916 FNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEG 1975
            F   G+ I +  +  +FITMNP Y G  ELP+NLK+LFRP AM+VP +++I EI+L + G
Sbjct: 1631 FVLEGKEIRINMSCAVFITMNPRYGGGVELPDNLKSLFRPVAMMVPHYQMIAEIILFSFG 1690

Query: 1976 FLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQ---V 2032
            F  A  L+ K   LY L ++ LS+QDHY++GLR++K VL++AG+ KR     +E     +
Sbjct: 1691 FKSANSLSGKLTNLYELARKQLSQQDHYNFGLRSLKIVLIMAGTKKREFKCLSEADETLI 1750

Query: 2033 LMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDS 2092
            ++ A+R+ ++PK   +D+P+F  +IGD+FP + V +   L  EK+I  +  +L LQ   S
Sbjct: 1751 VIEAIREASLPKCPPEDVPLFENIIGDIFPEVTVLKVNQLALEKVIYTATQQLGLQNWSS 1810

Query: 2093 FVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNL---------KRKPVA--- 2140
               K++Q    LQV   V +VG  G GK+ V + L K    L         +RK  +   
Sbjct: 1811 QKEKIIQFYNQLQVCVGVMLVGPTGGGKTTVRRILEKALTLLPIADFLSVAERKSASKIS 1870

Query: 2141 -----VD---LDPKAVTCDELFGIINPVTREWKDGLFSTIMR------------------ 2174
                 VD   L+PK VT  EL+G ++P T EW DGL S  +R                  
Sbjct: 1871 ERKGKVDICVLNPKCVTLSELYGQLDPNTMEWTDGLLSATIRSYVYFNTPKNTKKDIDLR 1930

Query: 2175 ------DLANI----------THDGP------------------KWIILDGDIDPMWIES 2200
                  DL+N+          T D                    +WIILDG +D  W+E+
Sbjct: 1931 LKSRISDLSNVFKLDSSDTTETDDNIFEEIEKVVKIPENHNFDWQWIILDGPVDTFWVEN 1990

Query: 2201 LNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPV 2260
            LN+V+DD + L LA++ERI L   +R++FE+ +L  A+PATVSR  ++Y++P DLGW P 
Sbjct: 1991 LNSVLDDTRTLCLANSERIALTNKIRVIFEVDNLSQASPATVSRCAMVYMDPVDLGWEPY 2050

Query: 2261 VSSWIERRKVQSEKANLMILFDKYLPTCLDKLRF--GFKKITPVP--EITVIQTILYLLE 2316
            V SW+ +      ++ +  L      +  D L+F    +K  P P  +ITV+ T+  +L+
Sbjct: 2051 VKSWLLKTSKIISQSGVDCLEFMIKNSVTDGLQFIRNRQKFQPYPMEDITVVITLCRILD 2110

Query: 2317 CL------------------------------LTEKTVP------------PDSPRELYE 2334
                                            +T K +             PD   ++ +
Sbjct: 2111 AFFDFMGKNGGFEQSDDLNDTSSKEANSQRESVTFKDIEKRDENTWYPEKNPDKLTKIIQ 2170

Query: 2335 LYFVFTCFWAFGGAMFQ----------------DQLVDYRVEFSK--------------- 2363
              FVF   WAFGGA+ +                D L     +F K               
Sbjct: 2171 KLFVFAFTWAFGGALNREDEHRENIPFCPSLEPDSLAKVTYDFDKLVHELFGNSSQVGWK 2230

Query: 2364 -WWINEFK-----TIKFPS-QGTIFDYYIDPDTKKFLPWTDKVPSFE--LDPDVPLQASL 2414
             W  ++ +      I  P+ + +IF Y++D +  +F+PW+D VP+ +  +     L  +L
Sbjct: 2231 HWGQSQGRRRKGNCINLPTGECSIFGYFVDIEQCEFIPWSDLVPNDQTLIQRGTSLLTNL 2290

Query: 2415 -------------------VHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKL 2455
                                 T +T  + + M LL++ S PV+L G +G GK+  +   L
Sbjct: 2291 QRSGGNFLKITECGECINYTATRDTTCLSFLMSLLLKNSCPVLLTGESGVGKTAAINQML 2350

Query: 2456 ESL 2458
            E L
Sbjct: 2351 EKL 2353



 Score =  134 bits (336), Expect = 3e-30
 Identities = 74/240 (30%), Positives = 125/240 (52%), Gaps = 2/240 (0%)

Query: 2464 LVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAP 2523
            +V  + F+   T+A  + ++ K L +++    G P   +++ FIDDMNMP  D YG   P
Sbjct: 2426 VVSTINFSTNVTAAKTKEMILKKLIRRTKDTLGAPKNNRILIFIDDMNMPVSDMYGAQPP 2485

Query: 2524 HTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSFPGQ 2583
              LIRQ +D    YD  K T K+I +   VA   P      I  RL +HF +  +  P Q
Sbjct: 2486 LELIRQLLDLGGVYDTEKNTWKNIQDLSIVAACVPVVND--ISPRLLKHFSMLVLPHPSQ 2543

Query: 2584 EALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVFNLR 2643
            + L TI+   L  + +  + +  +Q+   Q+++ +LA++ ++    LPT  K HY+FNLR
Sbjct: 2544 DILCTIFQAHLGIYFSINNFTPEVQKSKDQIISCSLAIYHQVRQNMLPTPTKCHYMFNLR 2603

Query: 2644 DLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFF 2703
            D+  +  GLL +   V+ +      L++HE  RV+ D+++D  D+   +R+     +  F
Sbjct: 2604 DMFKLLLGLLQADRTVVNSKEMAALLFVHEATRVFHDRLIDFTDKSLFYRLLSRELENCF 2663


>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
          Length = 4753

 Score =  158 bits (399), Expect = 1e-37
 Identities = 229/1063 (21%), Positives = 417/1063 (39%), Gaps = 163/1063 (15%)

Query: 1784 CFANICDAQIQYSYEYLGNTPRLVITP--LTDRCYITLTQSLHLIMGGAPAGPAGTGKTE 1841
            C+ ++      Y+YEYLG  PRL   P  L +R  + L  +L  +  G   GP G GK  
Sbjct: 1638 CWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKRA 1695

Query: 1842 TTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQ 1901
                L +ALG  + +  CS Q++ +   N   G  Q GAW   ++ +++   +LS +  +
Sbjct: 1696 IVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQR 1755

Query: 1902 V--------KCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGY-------AGRAELP 1946
            +           Q+A R          +++G        +++  GY       A  + +P
Sbjct: 1756 LGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVLRALSSAVP 1815

Query: 1947 ENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLS-------- 1998
             NL  L RP A+ +PD   + E+ L+  G  +A  +A +    ++L +EL+S        
Sbjct: 1816 ANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLP 1875

Query: 1999 --KQDHYDWGLRAIKSVLVVAGSLKRGDP---SRAEDQVLMRALRDFNIPKIVTDDLPVF 2053
              KQ   D     I+++ V     K   P   +  E+  L+R+     +  +   +L   
Sbjct: 1876 LLKQILED----TIRTLNVTKEEPKCQKPRSLAAIEEAALLRSPLFSILNGLHLHNL--- 1928

Query: 2054 MGLIGDLFPALDVPRKRDLNFEKIIKQSIVE----LKLQAEDSFVLKVVQLEELLQVRHS 2109
             GL+  LFP+        + + K++K  +VE    + L      +  + QL + L     
Sbjct: 1929 RGLLCALFPSASQVLAEPMTY-KLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASG 1987

Query: 2110 VFIVGNAGSGKSQVLKSLNKTYQNLKR---------KPVAVD-LDPKAVTCDELFGIINP 2159
            + ++G AGSGK+    SL K    L           +PV +  L P  ++  E  G +  
Sbjct: 1988 ILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEFLGWLEG 2047

Query: 2160 VTREWKDGLFSTIMRDLANITHDGPK-----------WIILDGDIDPMWIESLNTVMDDN 2208
                W  G+F  ++R      + G K           WII DG  +  W++S+  ++ + 
Sbjct: 2048 SC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSEL 2105

Query: 2209 KVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWI--- 2265
              L+L S ++I       L+ E++     +P  V    +++    +  W  ++S+ +   
Sbjct: 2106 PQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCG-GEQTWQCILSALMASL 2164

Query: 2266 --ERRKVQSEKANLMILFDKYLPTCLDKLRF-GFKKI----------TPVPEITVIQTIL 2312
              E R      A L  + +  +P  L  L   G   +            V E+T +  IL
Sbjct: 2165 PYEYRLQHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVCAGVAEVTSMARIL 2224

Query: 2313 YLLECL---LTEKTVP---------------------------------PDSPRE--LYE 2334
            + L  L   L E+  P                                 PD  RE  L  
Sbjct: 2225 HSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSDDVPDKCREHLLAV 2284

Query: 2335 LYFVFTCFWAFGGAMFQD--QLVDYRVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKF 2392
              F+F   W FG  +      + D  +  S   ++ +   + P    +FD ++ P+    
Sbjct: 2285 SSFLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYP--EPPPSALVFDLHVSPEDGTL 2342

Query: 2393 LPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMG 2452
            +P+T +  S  +   +    +   + +T R+ Y +DLL+    PV+L G A TGKS  + 
Sbjct: 2343 VPFTGQYLSSHIKGTL---GTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFVE 2399

Query: 2453 DKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNM 2512
              +E  +   Y      F+      +L   ++   +      +       L++ ++D+++
Sbjct: 2400 VLVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLEDLHL 2459

Query: 2513 PEVDKYGTVAP-HTLIRQHMDHRHWYDRHKLTLKDIH-NCQYVACMN-PTSGSFTIDSRL 2569
               D   +  P    +RQ MD    Y    L L+ +     ++A +  P      +  RL
Sbjct: 2460 ATSDPEKSCQPVLETLRQAMDGT-VYAHSTLELQTLQPTVNFLATVTVPGYCERPLCPRL 2518

Query: 2570 QRHFCVFAVSFPGQEALTTIYNTILTQHL-AFRSVSMAIQRISSQLVAAALALHQKITAT 2628
             R F V A+    Q  L   +  I+   L  F SV    + ++  LV A++   + +   
Sbjct: 2519 FRLFTVLALESMTQATLLERHVPIIQAWLERFPSVERE-RALARGLVRASVEAWEAVCNC 2577

Query: 2629 FLPTAIKFHYVFNLRDLSNIF----------------------------QGLLFSTAEVL 2660
            F+P+ +  HY F+L  +S++                              GL  +   V+
Sbjct: 2578 FMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVM 2637

Query: 2661 KTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFF 2703
                ++VRLWLHE +R + D++   +++    ++ +   +  F
Sbjct: 2638 MATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVF 2680



 Score =  119 bits (298), Expect = 7e-26
 Identities = 157/722 (21%), Positives = 292/722 (40%), Gaps = 77/722 (10%)

Query: 2768 HICRINRILESPRGNALLV-GVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDL 2826
            H+ R+ R+L  PR + LL+ G  G+G+ +   LA+ I     F +       I     D 
Sbjct: 2871 HVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCLRDA 2930

Query: 2827 AAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLA---SGEIPGLFMEDEVENIISSM 2883
            +     A + + P V L+  S V     L  ++ LLA   SG  PG + E +++ I   +
Sbjct: 2931 SWH---AGMLSQP-VALLVPSGVD----LTTLHRLLALATSGSFPGQYTEADLDRIGEHL 2982

Query: 2884 RPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCT--AID 2941
              +   +  N  +E   + F ++V   L +        +  ++ +  F  ++     +ID
Sbjct: 2983 PRENLGVKQNIKKEMVLQRFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATASID 3042

Query: 2942 WFHEWPEDALVSVSARFLEETEGIPWEVKA-SISFFMSYVHTTVNEMSRVYLATERRYNY 3000
             +  W + AL  V+   LE  + +P +  +       + + +    M+ ++L+    + +
Sbjct: 3043 RYEPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSATHYHEH 3102

Query: 3001 -------TTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLA 3053
                    TPKTFL+ +  +  L  +   ++  K +R++N L  L+    +       + 
Sbjct: 3103 LCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTHANLIF 3162

Query: 3054 IQEAELKQKNESADQLIQVVGIEAEKVSKEKAIAD--QEEVKVEVINKNVTEKQKACETD 3111
              E +LK   +S     Q   +E  K+  ++ + +   +E  +E + +     Q   E  
Sbjct: 3163 DLEQQLKDSGKSLSMFQQQ--LEQSKLLYKQQLEECRHQENLIENLARQRDALQAQREAF 3220

Query: 3112 LAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWK 3171
            L +   A L   E L  L   +  E++S+ +PP++VV VT A+  L         +  W 
Sbjct: 3221 LEQMSKAFL---EPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDL------FHHETGWA 3271

Query: 3172 AAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWC 3231
            +AK ++   D F   L  F KE I ++ L         P  D   +R+ S  AA L +W 
Sbjct: 3272 SAKQLLCTED-FYQELVFFPKEKITDSELIKLHLILKAPGMDDAALRAVSRPAASLAAWL 3330

Query: 3232 INIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATA 3291
              ++ +   +C   P    L++  A L   Q +L   + +  E   +   L    E A A
Sbjct: 3331 WAVLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQETLEHNLALAKMVEDAQA 3390

Query: 3292 E-----KIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLIS 3346
                  K   Q +    ++  + A      L +    W   ++  + + +T+ GD LL S
Sbjct: 3391 SHNCVAKTLSQAQCGQYHKWPMKA-----ALLTPMRAWTTQLQKLKGRCMTVFGDTLLCS 3445

Query: 3347 AFVSYVGYFTKKYRNELMEKFWIPYIHNLK------------------VPIPITNGL--- 3385
            A + Y+G F    R EL+++ W+      +                  V IP  N L   
Sbjct: 3446 AAIIYLGPFPPLRRQELLDE-WLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPLLAT 3504

Query: 3386 ----DPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTE-----RWPLIVDAQLQGIK 3436
                  LSLL+ +++   W+    P  + +     +L +       RWPL++D   + + 
Sbjct: 3505 HSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNEALI 3564

Query: 3437 WI 3438
            W+
Sbjct: 3565 WL 3566



 Score = 62.4 bits (150), Expect = 1e-08
 Identities = 196/1003 (19%), Positives = 347/1003 (34%), Gaps = 145/1003 (14%)

Query: 3544 LEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALV 3603
            LE+Q+L  ++ +E P+LE    +L     +    ++  E+ LL  L   +         +
Sbjct: 3757 LEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFL 3816

Query: 3604 ENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQF 3663
             N+   +    ++     E +  +++       YRP       +   L+ L  + P++  
Sbjct: 3817 RNIVRAQGKLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCM 3876

Query: 3664 SLKAFNVVFEKAIQRTTP---------ANEVKQRVINLTDEITYSVYMYTARGLFERDKL 3714
            S + +  V ++A+    P         A+ + Q   +LT ++  S    TA GL +   +
Sbjct: 3877 SPENWLAVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTV--TALGLTQVPLV 3934

Query: 3715 IFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVS-----PVDFLQHQGWGGIKALSEM 3769
              L  +     + K      EL+ L  +P  A   S     PV  +    W G KA  E 
Sbjct: 3935 GALGALALLQATGKAS----ELERLALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHEC 3990

Query: 3770 D------EFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTAL-QKLCMVRCLRPD 3822
            +       F  L + + G +  W+  +   +      P       +L QKL + R LRP+
Sbjct: 3991 EMLELLPPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPE 4050

Query: 3823 RMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALG--K 3880
             +  A+ +F    +G    E      +  ++ S  +  +  +L P   P   +  L   +
Sbjct: 4051 CLAGALADFTTSLLGRPLDENTYAP-TMPFKHSQATQPMLILLPPPGHPSATLHPLTVIQ 4109

Query: 3881 KLGFTIDNGKLHNVSLGQGQEV-----VAENALDVAAEKGHWVILQVRGGQHCRNIHLVA 3935
            KL      G+     +  G E      V  + L  A  +GHW++L         N HL+ 
Sbjct: 4110 KLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLD--------NCHLMP 4161

Query: 3936 RW-----------LG------------TLDKKLERYSTGSHEDYRVFISAEPAPSPETHI 3972
             W           LG             LD+   R  +  H D+R+++     P+  +  
Sbjct: 4162 HWPKELLQLLLELLGRAKVVADLESEQLLDQPESRNVSTVHRDFRLWLI---VPAESSAS 4218

Query: 3973 IPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVA 4032
            +P      A+   +  P   + +L     L     L      M+       L   H ++ 
Sbjct: 4219 LP------AVLTQHSMPVFWNQSLELGHVLIDSVELAQQVLYMQPPTQALPLLLLHGLLL 4272

Query: 4033 ERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDW 4092
             R+ +G +       ++   LT  +    + L A+   P   ++ L   + YGG + D  
Sbjct: 4273 HRQLYGTRLQAHRGRWSQVTLT-QVLQTQDQLWASLSNPRAAMQELAASVFYGGPLGDTE 4331

Query: 4093 DRR----LCRTYLA----EYIRTEMLEGDVLLAPGFQIPP--NLDYKGYHEYIDENLP-P 4141
            DR     L +  L+     +++    +   LLA    +P    LD     +     LP P
Sbjct: 4332 DREALISLTQACLSPSSGSWVQPHTPQS--LLATLMPLPELRELDAMAECKAQMHLLPSP 4389

Query: 4142 ESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSER 4201
              P L GL    +   L   S  L   +    P                      +P  R
Sbjct: 4390 PEPRLCGLSEGPQAWLLRRQSRALLSALQRSSP--------------------VWVPESR 4429

Query: 4202 KGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAA-----EKTPYVVVAFQ 4256
            +G  L  RR        QV   L+ + + +       E  A  +      + P   V   
Sbjct: 4430 RGAQLAERR--LRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPLEGVLET 4487

Query: 4257 ECERMNILTNEMRRSLKELNLGLKGELTI-TTDVEDLSTALFYDTVPDTWVARAYPSMMG 4315
            E   ++ L   ++R L  L   LKG     +     ++ AL+   +P  W   A      
Sbjct: 4488 EALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQP 4547

Query: 4316 LAAWY------ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAI-----MQSMAR 4364
               W         LL+R   + A  +         L+ F +P+  L A+     +     
Sbjct: 4548 PWHWLRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALDQNVP 4607

Query: 4365 KNEWPLDKMCLSVEVTKKNREDMTAP-------------PREGSYVYGLFMEGARWDTQT 4411
             + +P  +  +S ++  K  E  + P             P  G  + GL +  A WD   
Sbjct: 4608 SSNFPGSRGSVSSQLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAEWDPIA 4667

Query: 4412 GVIAEARLKELTPAMPVIFIKAIP----VDRMETKNIYECPVY 4450
            G + ++   + +P  PV      P    +       +Y CPVY
Sbjct: 4668 GALQDSPSSQPSPLPPVSISTQAPGTSDLPAPADLTVYSCPVY 4710



 Score = 44.7 bits (104), Expect = 0.002
 Identities = 70/406 (17%), Positives = 153/406 (37%), Gaps = 56/406 (13%)

Query: 1256 EVPVPDYKQLKACH-REVRLLKELWDMVVVVNTSIEDWKTTKWKDINV----EQMDIDCK 1310
            E PVP    L  C  R +   + +W +  V++ +I +WK   +   +     E+ +    
Sbjct: 1002 ETPVP----LPICGTRPIVQQQRIWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLT 1057

Query: 1311 KFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQV-K 1369
            + A+   +L+         + +    ++ +  L  +  L   ++   + Q L++A  +  
Sbjct: 1058 EAARMSTTLELHSPVLQHCMRILGEFRSYLPLLTKLGSLHPQSL---NCQCLLRALGLGS 1114

Query: 1370 FKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQ------ 1423
             +  E  TL  LL   L  + D +  +     +    ++ ++ L   W   + +      
Sbjct: 1115 LQTIELLTLGQLLTYPLLEFADRINQVWQNENERIHAQETIRRLQRYWEARQLRLLNFIL 1174

Query: 1424 HEPHPR----------------------TGTMMLKSSEVLVETLEDNQVQLQNLMMSKYL 1461
            H P+                        +GT +L     L ++++++   L  ++  +  
Sbjct: 1175 HVPYEPPASERSKRQVLRSPQWEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKS 1234

Query: 1462 AHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGD--SQRFDDI 1519
                K    W   +    +++ +W   Q+ W  L  +     +++ Q P    + RF  +
Sbjct: 1235 GDLNKIALEWVAIMHGLGALLEVWLTFQQKWIFLNKVL---HEMKIQFPNADLNSRFKVM 1291

Query: 1520 NQEFKALMEDAVKTPNVV-----EATSKP-----GLYNKLEALKKSLAICEKALAEYLET 1569
            + +++ LM  +V  P V+      A   P      L   L+A    L     +L   L  
Sbjct: 1292 DDQYRTLMRISVADPMVLSLVVPSAERSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYG 1351

Query: 1570 KRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFR 1615
                FPR +F+S ++L+ +L+   +  E    + + F  +  + FR
Sbjct: 1352 VCAHFPRLFFLSDSELVALLAARLESCEAQLWVRRCFPHVHAVSFR 1397


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 47.8 bits (112), Expect = 3e-04
 Identities = 99/485 (20%), Positives = 189/485 (38%), Gaps = 86/485 (17%)

Query: 3236 RFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE---LNANLSNLTSAFEKATAE 3292
            R  EV   +  K Q L+E   +L   QE++S ++ KI E   L   L N     E    E
Sbjct: 1121 RLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETE 1180

Query: 3293 KIKCQQ-------EADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLI 3345
            +++  Q       E  +  +   +   L     +E       +    + G+    ++ + 
Sbjct: 1181 RLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIA 1240

Query: 3346 SAFVSYVGYFTKKYRNELMEKFW-------IPYIHN-LKVPIPITNGLDPLSLLTDDADV 3397
               +        + R  + EK         +   H  L+  IP+ +  +   LL +  +V
Sbjct: 1241 HIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLH--EEQELLPNVKEV 1298

Query: 3398 A----TWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQ 3453
            +    T N   L +++ +T+++T L   E   L ++ + Q       + + E+K++   +
Sbjct: 1299 SETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQ-------ESQEEIKSLTK-E 1350

Query: 3454 KSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRL 3513
            +  L  I++A+      L E+I ET+  + +     +  K+ + + + +K+ E     ++
Sbjct: 1351 RDNLKTIKEALEVKHDQLKEHIRETLAKIQE-----SQSKQEQSLNMKEKDNE---TTKI 1402

Query: 3514 ILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNE 3573
            +   + F P     ++ +  ++          D++ +  VAKE+ DL++L+  L    ++
Sbjct: 1403 VSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKS--VAKEKDDLQRLQEVLQSESDQ 1460

Query: 3574 FKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEA--KITEVKIN 3631
             K  +KE+                            KH  +E E KV     K  E  IN
Sbjct: 1461 LKENIKEI--------------------------VAKHLETEEELKVAHCCLKEQEETIN 1494

Query: 3632 EARENYRPAAERASLLYFILNDL-----NKINPVY----QFSLKAFNVVFEKAIQRTTPA 3682
            E R N        S +   L  +     NKI  +Y    QF++K  + V EK        
Sbjct: 1495 ELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEK-------V 1547

Query: 3683 NEVKQ 3687
            NE+KQ
Sbjct: 1548 NELKQ 1552



 Score = 46.2 bits (108), Expect = 7e-04
 Identities = 195/1049 (18%), Positives = 397/1049 (37%), Gaps = 186/1049 (17%)

Query: 3017 LAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIE 3076
            L++K TE+    ++LE    KLQ+   ++ + +     ++  +KQ +E  +++ ++   +
Sbjct: 1500 LSEKETEISTIQKQLEAINDKLQNKIQEIYEKE-----EQFNIKQISEVQEKVNELKQFK 1554

Query: 3077 AEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEAL----DTLNKN 3132
              + +K+ A+   E   +E+ N+ + E Q+  +  + K +  +   QEAL    D L +N
Sbjct: 1555 EHRKAKDSALQSIESKMLELTNR-LQESQEEIQI-MIKEKEEMKRVQEALQIERDQLKEN 1612

Query: 3133 N---LTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKK 3189
                + ++K         + +TA               + ++  K+ +  ++T    L +
Sbjct: 1613 TKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQ 1672

Query: 3190 FDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQ 3249
               E++ E           + T + + +RS               +R  E       K++
Sbjct: 1673 ILHENLEE---------MRSVTKERDDLRSVEETLKVERDQLKENLR--ETITRDLEKQE 1721

Query: 3250 ALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKAT----AEKIKCQQEADATNR 3305
             L+  +  L E QE + +++  ++E    +SN+    E +     A+ +K Q+E    + 
Sbjct: 1722 ELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHM 1781

Query: 3306 VILLANRLVG---GLASE---------------NIRWAESVENFRS---QGVTLCGDVLL 3344
             +      +    G+ SE               N +  E ++  ++   Q +TL  DV  
Sbjct: 1782 HLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNE 1841

Query: 3345 ISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQG 3404
                VS +    K+ +++ +    +  I NL +   +   L+ +  +  + D      + 
Sbjct: 1842 TQKKVSEMEQLKKQIKDQSLTLSKLE-IENLNLAQKLHENLEEMKSVMKERDNLRRVEET 1900

Query: 3405 LPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSY---LDVIE 3461
            L  +R   + +                LQ  K    + + ELK  R+  K +   +D + 
Sbjct: 1901 LKLERDQLKES----------------LQETKARDLEIQQELKTARMLSKEHKETVDKLR 1944

Query: 3462 QAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFN 3521
            + ISE  T+ I +I + +D   D L  +    + K +++   + + +   + I   +   
Sbjct: 1945 EKISE-KTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLK 2003

Query: 3522 PHYKPE---MQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVL 3578
              ++ +   MQ+   + NF +T+   E      +VAKER +L ++K +L   +++F   L
Sbjct: 2004 KQFEAQNLSMQS-VRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATL 2062

Query: 3579 KELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYR 3638
            +E    ++AR    +     +  L+   +  +H    + EK    K    + +E  ++Y 
Sbjct: 2063 RE----MIAR-DRQNHQVKPEKRLLS--DGQQHLTESLREKCSRIKELLKRYSEMDDHYE 2115

Query: 3639 PAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITY 3698
                R SL      DL K             + F+K +     AN     +  L  +   
Sbjct: 2116 -CLNRLSL------DLEK------------EIEFQKELSMRVKAN---LSLPYLQTKHIE 2153

Query: 3699 SVYMYTARGLFERDKLI-FLAQVTFQVLSMKKE----LNPVELDFLLRFPFKAGVVSPVD 3753
             ++    R   E  +++  L  V   V  +K+E    +N  E+DF+     +  ++  + 
Sbjct: 2154 KLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQ 2213

Query: 3754 FLQHQGWGGIKALSEMDEFKNLDSDIE-----------GSAKRWKKLVESEAPEKEIFPK 3802
             LQ       + L ++   +N+D  IE            S K   + V S   E   F +
Sbjct: 2214 HLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLE 2273

Query: 3803 EWKN--------KTALQK----LCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSK 3850
            EW N        K  +QK    +C V     +R+   +    E        E RS   SK
Sbjct: 2274 EWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTE-------FEERSATISK 2326

Query: 3851 SYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDV 3910
             +E+                   D+++L +K      N +    SL  G +V        
Sbjct: 2327 EWEQ-------------------DLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTT---- 2363

Query: 3911 AAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPET 3970
                           Q  +N H+ +R      +K+       HE      + E A   E+
Sbjct: 2364 ---------------QDNKNPHVTSRATQLTTEKIRELENSLHE------AKESAMHKES 2402

Query: 3971 HIIPQGILENAIKITNEPPTGMHANLHKA 3999
             II    ++  +++TN+    + A +H++
Sbjct: 2403 KIIK---MQKELEVTNDIIAKLQAKVHES 2428



 Score = 37.4 bits (85), Expect = 0.34
 Identities = 182/964 (18%), Positives = 364/964 (37%), Gaps = 195/964 (20%)

Query: 579  HKNMPPVAGQLKWSLELQERLEVSMKHLK-HVEHPVMSGAEAK-------LTYQKYDEMM 630
            ++ +  +  + K   ELQ+  E    HL+ ++     +G + K       +  +++ E +
Sbjct: 1192 YEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETI 1251

Query: 631  ELLRCHREKIYQQWVAGVD-QDCHFNLGQPL-ILRDAASNLIHVNFSKALVAVLREVKYL 688
            + LR    +   Q +   D +  H  L + + +L +    L +V         + E++ L
Sbjct: 1252 DELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELL 1311

Query: 689  NFQQQKEIPDSAESLFSENETFR---KFVGNLELIVGWYNEIKTIVKAVEFLLIKSELEA 745
               +Q    DS      E E  R   KF  + E       EIK++ K  + L  K+  EA
Sbjct: 1312 T--EQSTTKDSTTLARIEMERLRLNEKFQESQE-------EIKSLTKERDNL--KTIKEA 1360

Query: 746  IDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQNRMQKAKQNI---EGISQAMKDWSAN 802
            ++VK                Q  + +RE L  +Q    K +Q++   E  ++  K  S  
Sbjct: 1361 LEVKH--------------DQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEM 1406

Query: 803  PLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQAMVAENAELFRADTLSLPWKDY 862
              F+ KD+   ALL ++  +  L+KR     D   +++++  E  +L R        ++ 
Sbjct: 1407 EQFKPKDS---ALLRIEIEMLGLSKRLQESHD---EMKSVAKEKDDLQRL-------QEV 1453

Query: 863  VIYIDDMVLDEFDQFIRKSLS----FLMDNMVIDESIAPLFEIRMELDEDGL---TFNPT 915
            +    D + +   + + K L       + +  + E    + E+R+ L E      T    
Sbjct: 1454 LQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQ 1513

Query: 916  LEVGSDRGFLALIEGLVNDIY------NVARLIP--------------RLAKDRMNYKMD 955
            LE  +D+     ++  + +IY      N+ ++                R AKD     ++
Sbjct: 1514 LEAINDK-----LQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIE 1568

Query: 956  ---LEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAV 1012
               LE    L E +EE+  ++I   +E +  Q++ +    +  D L+E  K  +      
Sbjct: 1569 SKMLELTNRLQESQEEIQ-IMIKEKEEMKRVQEALQ----IERDQLKENTKEIVAKMKES 1623

Query: 1013 TAEDLDTWTDDTIPKTPPTLAQFQEQIDSYE--KLYEEVSKCEN---TKVFHGWLQ---- 1063
              ++        + +T   + + +   + +E  KL  E  + EN   T++ H  L+    
Sbjct: 1624 QEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRS 1683

Query: 1064 -CDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGL 1122
                R   +++  T++      K +L   +T  L   E  +K+  M L +   +   D L
Sbjct: 1684 VTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEE-LKIVHMHLKE--HQETIDKL 1740

Query: 1123 VEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLA 1182
              +      V E+     NM + L+ + + LK    ++ EE+ +    L E      KL 
Sbjct: 1741 RGI------VSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLR 1794

Query: 1183 IQVKLTVAPLQ------ANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLN 1236
              V      L        N  + L+ K Q+ +  +H+                       
Sbjct: 1795 GIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQL---------------------- 1832

Query: 1237 KVFLLKGIMEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTK 1296
             + L K + E   K        V + +QLK         K++ D  + ++          
Sbjct: 1833 -ITLKKDVNETQKK--------VSEMEQLK---------KQIKDQSLTLS---------- 1864

Query: 1297 WKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRE 1356
               + +E +++  +K  +++  +   MK  D    ++ T+K     L+    LQ    R+
Sbjct: 1865 --KLEIENLNL-AQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLK--ESLQETKARD 1919

Query: 1357 RHWQQLMQAT------------QVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKES 1404
               QQ ++              +++ K+SE+T     +Q +L   +DE++  + +  K  
Sbjct: 1920 LEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQK-- 1977

Query: 1405 GMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHF 1464
               K L+ L     + E  +  H +   M     +   + L    V++ N  ++K L   
Sbjct: 1978 ---KELQLL----RVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHES 2030

Query: 1465 LKEV 1468
            L+E+
Sbjct: 2031 LEEI 2034



 Score = 37.0 bits (84), Expect = 0.44
 Identities = 27/131 (20%), Positives = 63/131 (48%), Gaps = 8/131 (6%)

Query: 3007 LEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESA 3066
            +EQ K   + L +   E++   +RL+    +++S A + DDL+    + ++E  Q  E+ 
Sbjct: 1406 MEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENI 1465

Query: 3067 DQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEAL 3126
             +++       E++        ++E  +  +  N++EK    ET+++  +  L    EA+
Sbjct: 1466 KEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEK----ETEISTIQKQL----EAI 1517

Query: 3127 DTLNKNNLTEL 3137
            +   +N + E+
Sbjct: 1518 NDKLQNKIQEI 1528


>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
          Length = 783

 Score = 45.8 bits (107), Expect = 0.001
 Identities = 46/223 (20%), Positives = 101/223 (45%), Gaps = 29/223 (13%)

Query: 1262 YKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDK 1321
            Y+ +   HR+VR L++  +++ +         T   +   ++Q +   K+   + R  D+
Sbjct: 411  YQNVDELHRQVRTLQDKENLLEM---------TCSQQQSRIQQQEALLKQLENEKRKYDE 461

Query: 1322 EMKTWDAFVGLDNTVKNVITSLRA----VSELQNPAIR---ERHWQQLMQATQVKFKMSE 1374
             +K+        + ++    +LR     + +L N  +R   E+H QQ ++  +VK++++ 
Sbjct: 462  HVKSNQELSEKLSKLQQEKEALREEYLRLLKLLNVHVRNYNEKHHQQKVKLQKVKYRLTN 521

Query: 1375 ETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTW---------SMMEFQHE 1425
            E  L D     ++ +EDE+  +  K  KE  ++  + A + T           ++E +  
Sbjct: 522  EVELRD---KRINQFEDEIGILQHKIEKEKAIQDQITAQNDTLLLEKRKLQEQVIEQEQL 578

Query: 1426 PHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEV 1468
             H    T+    S VL    E+ Q+Q  +L +++ +  FL+ +
Sbjct: 579  IHSNKWTISSIQSRVLYMDKENKQLQENSLRLTQQIG-FLERI 620


>gi|34577114 cytomatrix protein p110 [Homo sapiens]
          Length = 957

 Score = 43.9 bits (102), Expect = 0.004
 Identities = 86/381 (22%), Positives = 155/381 (40%), Gaps = 71/381 (18%)

Query: 3004 KTFLEQIKLYQNLLAKKRTELVA---KIERLENG---------LMKLQSTA--------- 3042
            KT ++Q+K     L+KK +EL+A   K+E L N          ++K   TA         
Sbjct: 433  KTKIDQLK---QELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQ 489

Query: 3043 SQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINK--- 3099
            ++VD L+ +L  +E+ L +K +    L +  G  A ++   K + + +E K+ V+ K   
Sbjct: 490  TEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIE 549

Query: 3100 --------------NVTEKQKACETDLAKAEPALLAAQEAL--------------DTLNK 3131
                          N+ ++ K+ +TD +  + AL   +EAL              +  ++
Sbjct: 550  NLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDR 609

Query: 3132 NNLTELKSFGSP-PDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMG-KVDTFLDSL-- 3187
              L E++SF     D    V A    LT     +   K   ++    G K D+ L SL  
Sbjct: 610  ERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEI 669

Query: 3188 ---KKFDKEHIPEACLKAFKPYQGNPTFDPEF---IRSKSTAAAGLCSWC----INIVRF 3237
               +K ++    EA LK     + +   +PEF   I+     A+     C      + R 
Sbjct: 670  AIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRL 729

Query: 3238 YEVYCDVAPKRQALEEANAELAEAQEKLSRIKN-KIAELNANLSNLTSAFEKATAEKIKC 3296
             E+  +V  ++   ++  AEL     +  + +N K+A L  N   L         E+++ 
Sbjct: 730  LEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHN-QQLEKKKNAQLLEEVRR 788

Query: 3297 QQEADATNRVILLANRLVGGL 3317
            ++++ A N   L    L+  L
Sbjct: 789  REDSMADNSQHLQIEELMNAL 809


>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
          Length = 2028

 Score = 42.0 bits (97), Expect = 0.014
 Identities = 63/343 (18%), Positives = 139/343 (40%), Gaps = 25/343 (7%)

Query: 3007 LEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNES- 3065
            LE+  L    L K+  +L  KIE+L+  L + + +   ++ L  +L  ++ +L+   E+ 
Sbjct: 489  LEESGLKCGELEKENHQLSKKIEKLQTQLEREKQSNQDLETLSEELIREKEQLQSDMETL 548

Query: 3066 -ADQLIQVVGIEAEKVSKEKA---IADQEEVKVEVINKNVTEKQKACETDLAKAEPALLA 3121
             AD+  Q+  +E EK    +A   + ++ +V  E   K+V ++ KA    + +A   L  
Sbjct: 549  KADKARQIKDLEQEKDHLNRAMWSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQ 608

Query: 3122 AQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVD 3181
             +     L++ +L + K  G   +    +   +  L    G++ +          +  ++
Sbjct: 609  LEFEKRQLHR-DLEQAKEKG---ERAEKLERELQRLQEENGRLAR---------KVTSLE 655

Query: 3182 TFLDSLKKFDKE----HIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRF 3237
            T  + ++  + E     +    L+       N +   E +   +     L +  + + R 
Sbjct: 656  TATEKVEALEHESQGLQLENRTLRKSLDTLQNVSLQLEGLERDNKQ---LDAENLELRRL 712

Query: 3238 YEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQ 3297
             E     + K   +E  N +L   +E+L +  + +  L      L  +++  +AE ++ Q
Sbjct: 713  VETMRFTSTKLAQMERENQQLEREKEELRKNVDLLKALGKKSERLELSYQSVSAENLRLQ 772

Query: 3298 QEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCG 3340
            Q  ++++         +G L +E       +E  R     L G
Sbjct: 773  QSLESSSHKTQTLESELGELEAERQALRRDLEALRLANAQLEG 815


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 41.6 bits (96), Expect = 0.018
 Identities = 54/281 (19%), Positives = 120/281 (42%), Gaps = 64/281 (22%)

Query: 1179 KKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLN-- 1236
            KK+  +    +  LQ NE S++R+     EL++   +E  +++      +    + +   
Sbjct: 876  KKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRKENEKQKNELLSMEAEVCEKIGCL 935

Query: 1237 ------KVFLLKGIMEALSKSGGLFEVPVPD--YKQLKACHREVRLLKELWDMVVVVNTS 1288
                   +F +  + + +  S  L E+ + +  Y +L A +R++ L K   D ++V  TS
Sbjct: 936  QRFKEMAIFKIAALQKVVDNSVSLSELELANKQYNELTAKYRDI-LQK---DNMLVQRTS 991

Query: 1289 IEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEM-----------KTWDAFVGLDN--- 1334
                        N+E ++ +     + + S++KE+           + W+    L N   
Sbjct: 992  ------------NLEHLECENISLKEQVESINKELEITKEKLHTIEQAWEQETKLGNESS 1039

Query: 1335 --------TVKNVITSLRAVSELQNPAIRER----HWQQLMQATQVKFKMSE------ET 1376
                    T  ++++  + ++ L+   + ER    H Q++ +  +   K  E      ET
Sbjct: 1040 MDKAKKSITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELET 1099

Query: 1377 TLADLLQLNLHSYE------DEVRNIVDKAVKESGMEKVLK 1411
              A+L ++NL + +      DE+ + V KAV ++  +++L+
Sbjct: 1100 KFAELTKINLDAQKVEQMLRDELADSVSKAVSDADRQRILE 1140



 Score = 37.0 bits (84), Expect = 0.44
 Identities = 31/130 (23%), Positives = 63/130 (48%), Gaps = 13/130 (10%)

Query: 3008 EQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQ----VDDLKAK-----LAIQEAE 3058
            E+I++    + K   E V ++E++ +   ++++   Q    +D LK +     L +QE  
Sbjct: 230  EKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELT 289

Query: 3059 --LKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAE 3116
              LK KNE  D ++  V  + E+     +  D E ++ + +  N+ EK K  + D  K+ 
Sbjct: 290  DLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKSN 349

Query: 3117 PALLAAQEAL 3126
              ++A Q+ +
Sbjct: 350  --VMALQQGI 357



 Score = 35.4 bits (80), Expect = 1.3
 Identities = 51/241 (21%), Positives = 89/241 (36%), Gaps = 40/241 (16%)

Query: 3009 QIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQ 3068
            Q+ ++     K   +++A+ ERL   L K    A ++   K  L I   ++  + E   +
Sbjct: 2187 QLSMHYESKTKGTEKIIAENERLRKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGK 2246

Query: 3069 LIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALL-------A 3121
             +Q     AE    +   AD +  K  V+ +    K K  ETD+AK   ++         
Sbjct: 2247 RLQF----AESRGPQLEGADSKSWKSIVVTRMYETKLKELETDIAKKNQSITDLKQLVKE 2302

Query: 3122 AQEALDTLNKNN------LTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKS-----W 3170
            A E    +NK N      +  LK      +    +   + +L     ++ K+K+      
Sbjct: 2303 ATEREQKVNKYNEDLEQQIKILKHVPEGAETEQGLKRELQVLRLANHQLDKEKAELIHQI 2362

Query: 3171 KAAKIMMGKVDTFLDS---------------LKKFDKEHIPEACLKAFKPYQGNPTFDPE 3215
            +A K   G   T  D+               +   +K+H+ E   K  K  +    FDP 
Sbjct: 2363 EANKDQSGAESTIPDADQLKEKIKDLETQLKMSDLEKQHLKEEIKKLKKELE---NFDPS 2419

Query: 3216 F 3216
            F
Sbjct: 2420 F 2420



 Score = 35.0 bits (79), Expect = 1.7
 Identities = 31/126 (24%), Positives = 63/126 (50%), Gaps = 7/126 (5%)

Query: 3007 LEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDD--LKAKLAIQEAELKQKNE 3064
            LE+++      AK   +L  K+ +LEN L   Q +A   D   L+ ++   E +L+QK+ 
Sbjct: 70   LEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDR 129

Query: 3065 SADQLIQVVGIEAEKVSKEKAI----ADQEEVKVEVINKNVTEKQKACETDLAKAEPALL 3120
              + + + +  E +KV+++ A+    A+ E  K+   NK + +K +    D+   +  + 
Sbjct: 130  ELEDMEKELEKE-KKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQID 188

Query: 3121 AAQEAL 3126
            + +E L
Sbjct: 189  SQKETL 194



 Score = 32.7 bits (73), Expect = 8.3
 Identities = 56/265 (21%), Positives = 106/265 (40%), Gaps = 41/265 (15%)

Query: 3560 LEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVE---NLE--TTKHTAS 3614
            +E+LK+ L   + + K + + L +      +AA    +  T+  E   N++    +HT  
Sbjct: 1727 VERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTR- 1785

Query: 3615 EIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEK 3674
            E++ +V +     +K+ EA    + +  R + L   LNDLN      Q   KA+N +  +
Sbjct: 1786 ELKTQVEDLNENLLKLKEA---LKTSKNRENSLTDNLNDLNN---ELQKKQKAYNKILRE 1839

Query: 3675 AIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPV 3734
              +     +E+K+++  LT  +         + L E        ++  +V  ++ +L   
Sbjct: 1840 KEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIE--------ELQRKVKKLENQLE-- 1889

Query: 3735 ELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKK------ 3788
                        G V  VD    +     + L   +E K   + IEG   + K+      
Sbjct: 1890 ------------GKVEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKEGEVF 1937

Query: 3789 -LVESEAPEKEIFPKEWKNKTALQK 3812
             L +     K++F K  K K  LQ+
Sbjct: 1938 TLTKQLNTLKDLFAKADKEKLTLQR 1962


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 41.6 bits (96), Expect = 0.018
 Identities = 93/479 (19%), Positives = 182/479 (37%), Gaps = 77/479 (16%)

Query: 1151 ELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELK 1210
            + L++  +E    I  +L+ L E WA+    ++  + T+  + +     + RK Q     
Sbjct: 2697 QALRSSNKEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQL---- 2752

Query: 1211 QHEFRERFRREAPFSFSDP-NPYKSLNKVFLLKGIMEALSKSGGLFEVPVPDYKQLKACH 1269
                 E++          P  P   L + F+L   ++++                 +A H
Sbjct: 2753 -----EQWMESVDQKIEHPLQPQPGLKEKFVLLDHLQSILSEAE---------DHTRALH 2798

Query: 1270 REVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAF 1329
            R +   +EL++      T  E +K T  +++  +  DI        M    ++M+     
Sbjct: 2799 RLIAKSRELYE-----KTEDESFKDTAQEELKTQFNDI--------MTVAKEKMRK---- 2841

Query: 1330 VGLDNTVKNVITSLRAVSELQN---PAIRERH-WQQLM---QATQVKFKMSEETTLADLL 1382
              ++  VK+ +  L AV E  +    A  E H W  +     ATQ K    +E   +  +
Sbjct: 2842 --VEEIVKDHLMYLDAVHEFTDWLHSAKEELHRWSDMSGDSSATQKKLSKIKELIDSREI 2899

Query: 1383 QLNLHSYEDEVRNIVDKAVKESGMEKV---LKALDSTWSMME---FQHEPHPRTGTMMLK 1436
              +  S  + +   V +    SG E +   ++AL + W   E   FQ        T    
Sbjct: 2900 GASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQ--------TQSCL 2951

Query: 1437 SSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLS------TADSVISIWFEVQR 1490
             + V    L + +   Q   + + L  F   + +W Q+L+      T + ++  W + Q 
Sbjct: 2952 ENLVSQMALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQE 3011

Query: 1491 TWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLE 1550
                L+     +ED+++QL  +  RF      +   +   +K  N +   +  G  NK +
Sbjct: 3012 ILDALQKAEPRTEDLKSQL-NELCRFSRDLSTYSGKVSGLIKEYNCLCLQASKGCQNKEQ 3070

Query: 1551 ALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSL 1609
             L++      +   ++L   +        +++A   DI  N +   EVS  L K+ + L
Sbjct: 3071 ILQQRFRKAFRDFQQWLVNAK--------ITTAKCFDIPQNIS---EVSTSLQKIQEFL 3118



 Score = 36.6 bits (83), Expect = 0.58
 Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 13/113 (11%)

Query: 3560 LEQLKANLTKSQNEFKIVLKELED--SLLARLSAASGNFLGDTALVENLETTKHTASEIE 3617
            ++ ++ANL +S+ +      EL D  ++L +    +   L  ++L+E +E          
Sbjct: 3412 MDSMEANLNESERQHA----ELRDKTTMLGKAKLLNEEVLSYSSLLETIEVKG------- 3460

Query: 3618 EKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNV 3670
              + E  +T++++ + +E YR   ERA         L +++  YQ  LKAF V
Sbjct: 3461 AGMTEHYVTQLELQDLQERYRAIQERAKEAVTKSEKLVRLHQEYQRDLKAFEV 3513


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 41.6 bits (96), Expect = 0.018
 Identities = 93/479 (19%), Positives = 182/479 (37%), Gaps = 77/479 (16%)

Query: 1151 ELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELK 1210
            + L++  +E    I  +L+ L E WA+    ++  + T+  + +     + RK Q     
Sbjct: 2690 QALRSSNKEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQL---- 2745

Query: 1211 QHEFRERFRREAPFSFSDP-NPYKSLNKVFLLKGIMEALSKSGGLFEVPVPDYKQLKACH 1269
                 E++          P  P   L + F+L   ++++                 +A H
Sbjct: 2746 -----EQWMESVDQKIEHPLQPQPGLKEKFVLLDHLQSILSEAE---------DHTRALH 2791

Query: 1270 REVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAF 1329
            R +   +EL++      T  E +K T  +++  +  DI        M    ++M+     
Sbjct: 2792 RLIAKSRELYE-----KTEDESFKDTAQEELKTQFNDI--------MTVAKEKMRK---- 2834

Query: 1330 VGLDNTVKNVITSLRAVSELQN---PAIRERH-WQQLM---QATQVKFKMSEETTLADLL 1382
              ++  VK+ +  L AV E  +    A  E H W  +     ATQ K    +E   +  +
Sbjct: 2835 --VEEIVKDHLMYLDAVHEFTDWLHSAKEELHRWSDMSGDSSATQKKLSKIKELIDSREI 2892

Query: 1383 QLNLHSYEDEVRNIVDKAVKESGMEKV---LKALDSTWSMME---FQHEPHPRTGTMMLK 1436
              +  S  + +   V +    SG E +   ++AL + W   E   FQ        T    
Sbjct: 2893 GASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQ--------TQSCL 2944

Query: 1437 SSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLS------TADSVISIWFEVQR 1490
             + V    L + +   Q   + + L  F   + +W Q+L+      T + ++  W + Q 
Sbjct: 2945 ENLVSQMALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQE 3004

Query: 1491 TWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLE 1550
                L+     +ED+++QL  +  RF      +   +   +K  N +   +  G  NK +
Sbjct: 3005 ILDALQKAEPRTEDLKSQL-NELCRFSRDLSTYSGKVSGLIKEYNCLCLQASKGCQNKEQ 3063

Query: 1551 ALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSL 1609
             L++      +   ++L   +        +++A   DI  N +   EVS  L K+ + L
Sbjct: 3064 ILQQRFRKAFRDFQQWLVNAK--------ITTAKCFDIPQNIS---EVSTSLQKIQEFL 3111



 Score = 36.6 bits (83), Expect = 0.58
 Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 13/113 (11%)

Query: 3560 LEQLKANLTKSQNEFKIVLKELED--SLLARLSAASGNFLGDTALVENLETTKHTASEIE 3617
            ++ ++ANL +S+ +      EL D  ++L +    +   L  ++L+E +E          
Sbjct: 3405 MDSMEANLNESERQHA----ELRDKTTMLGKAKLLNEEVLSYSSLLETIEVKG------- 3453

Query: 3618 EKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNV 3670
              + E  +T++++ + +E YR   ERA         L +++  YQ  LKAF V
Sbjct: 3454 AGMTEHYVTQLELQDLQERYRAIQERAKEAVTKSEKLVRLHQEYQRDLKAFEV 3506


>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
          Length = 1979

 Score = 41.2 bits (95), Expect = 0.023
 Identities = 63/303 (20%), Positives = 131/303 (43%), Gaps = 30/303 (9%)

Query: 3044 QVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQE----EVKVEVINK 3099
            ++++L+  L  ++A ++   E+  +L   +   +E   KE    D E    + K +V+ K
Sbjct: 1348 ELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDVLQK 1407

Query: 3100 NVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTA 3159
             + EK    +   AK++  L + +   + +N+N L           AV N+   ++IL  
Sbjct: 1408 LLKEKDLLIK---AKSDQLLSSNENFTNKVNENELLR--------QAVTNLKERILILEM 1456

Query: 3160 PGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPY--QGNPTFDPEFI 3217
              GK+ K ++ K  +   GK +T   +L++ + +       K F+ +  +       + +
Sbjct: 1457 DIGKL-KGENEKIVETYRGK-ETEYQALQETNMKFSMMLREKEFECHSMKEKALAFEQLL 1514

Query: 3218 RSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQ-----ALEEANAELAEAQEKLSRIKNKI 3272
            + K     G  +  +N V+  +    V  + +     AL++   E    Q ++ R+++K 
Sbjct: 1515 KEKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKE 1574

Query: 3273 AELNANL----SNLTSAFEKATAEKIKCQ-QEADATNRVILLANRLVGGL-ASENIRWAE 3326
               N  L    ++L  + +  T E +  + +EA    +V +L  +LV    A EN     
Sbjct: 1575 FRSNQELERLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQA 1634

Query: 3327 SVE 3329
            SV+
Sbjct: 1635 SVQ 1637


>gi|4502395 beclin 1 [Homo sapiens]
          Length = 450

 Score = 40.8 bits (94), Expect = 0.031
 Identities = 33/130 (25%), Positives = 56/130 (43%), Gaps = 3/130 (2%)

Query: 3005 TFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNE 3064
            T L+Q+    N+   +       +E LE      +  + Q+     +LA++E  L Q+ E
Sbjct: 143  TLLDQLDTQLNVTENECQNYKRCLEILEQ---MNEDDSEQLQMELKELALEEERLIQELE 199

Query: 3065 SADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQE 3124
              ++  ++V    EKV  E    DQEE + +        +Q   + +L   E  +  AQ 
Sbjct: 200  DVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQT 259

Query: 3125 ALDTLNKNNL 3134
             LD L K N+
Sbjct: 260  QLDKLKKTNV 269


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 39.3 bits (90), Expect = 0.089
 Identities = 35/170 (20%), Positives = 80/170 (47%), Gaps = 19/170 (11%)

Query: 2981 HTTVNEMS-----RVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGL 3035
            H+T  E++     R  L TE +  +   K+ L Q++  +++L K +  L  K   +++  
Sbjct: 1049 HSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLT 1108

Query: 3036 MKLQSTASQVDDLKAKLAIQEAELKQKN-ESADQLIQVVGIE----------AEKVSKEK 3084
             +L+    +++D K +L   +  LK++N E   +  QV  ++           +K+ K +
Sbjct: 1109 AELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLE 1168

Query: 3085 AIADQEEVKVEVINKNV---TEKQKACETDLAKAEPALLAAQEALDTLNK 3131
               ++ E++++  NK +    +K +  +  L + E  +L  ++ +  L K
Sbjct: 1169 GTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKK 1218



 Score = 34.7 bits (78), Expect = 2.2
 Identities = 56/290 (19%), Positives = 110/290 (37%), Gaps = 38/290 (13%)

Query: 3018 AKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEA 3077
            +K  +E+  K  +L     +L+        + AK A  E EL +KNE    L   +  E 
Sbjct: 686  SKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEH 745

Query: 3078 EKVSKEKAIADQEEVKVEVINKNVTEKQ-KACETDLAKAEPALLAAQEALDTLNKNNLTE 3136
            EK+     +A ++  K+ +      EKQ +  E  L K +      ++ +  L ++ + +
Sbjct: 746  EKI----CLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICK 801

Query: 3137 LKSFGSPPDAVVNVTAAVMILTAPGGKIPKD--KSWKAAKIMMGKVDTFLDSLKKFDK-- 3192
                        ++ +   +LT   G++ K+  K  +A K +  +V      +++ D   
Sbjct: 802  QH----------HLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSAL 851

Query: 3193 EHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYC---DVAPKRQ 3249
            E   E  +      +GN     + ++ KS                 EVYC   ++  K  
Sbjct: 852  EICKEELVLHLNQLEGNKEKFEKQLKKKSE----------------EVYCLQKELKIKNH 895

Query: 3250 ALEEANAELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQE 3299
            +L+E + +    Q  L + +  + +       L     K   +  K +QE
Sbjct: 896  SLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQE 945


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sapiens]
          Length = 1116

 Score = 38.9 bits (89), Expect = 0.12
 Identities = 66/350 (18%), Positives = 134/350 (38%), Gaps = 50/350 (14%)

Query: 3017 LAKKRTELVA---KIERLEN---------GLMKLQSTA---------SQVDDLKAKLAIQ 3055
            L++K TEL+A   K+E L N          ++K   TA         ++VD L+ +L  +
Sbjct: 475  LSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEK 534

Query: 3056 EAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKA 3115
            E  L +K +    + +  G +A ++   K + D +E KV V+ K +   Q+     L   
Sbjct: 535  ETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQE----QLRDK 590

Query: 3116 EPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKS------ 3169
            E  + + +E + +L  +      +  +  +A+      +  L     +  ++K       
Sbjct: 591  EKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNY 650

Query: 3170 WKAAKIMMGKVDTFLDSLKKFD------KEHIPEACLKAFKPYQGNPTFDPEFIRSKSTA 3223
             K  K +  KV      L + +      KEH         K      T +    + K   
Sbjct: 651  KKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEE- 709

Query: 3224 AAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANLSNLT 3283
                   C+ +    +   + A + +A  E +  +   + +++R K++ ++  A +  L 
Sbjct: 710  -------CLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 762

Query: 3284 SAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRS 3333
               ++   EK    ++     R +   N+ V      N++  E VE  +S
Sbjct: 763  EILKEVENEKNDKDKKIAELERQVKDQNKKVA-----NLKHKEQVEKKKS 807


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 158,629,306
Number of Sequences: 37866
Number of extensions: 6923556
Number of successful extensions: 20388
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 135
Number of HSP's that attempted gapping in prelim test: 18963
Number of HSP's gapped (non-prelim): 1219
length of query: 4485
length of database: 18,247,518
effective HSP length: 123
effective length of query: 4362
effective length of database: 13,590,000
effective search space: 59279580000
effective search space used: 59279580000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 73 (32.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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