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Search of human proteins with 239750438
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239750438 PREDICTED: hypothetical protein [Homo sapiens]
(510 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239750438 PREDICTED: hypothetical protein [Homo sapiens] 1046 0.0
gi|239744740 PREDICTED: hypothetical protein XP_002343259 [Homo ... 776 0.0
gi|239755920 PREDICTED: hypothetical protein XP_002344746 [Homo ... 768 0.0
gi|239750574 PREDICTED: hypothetical protein [Homo sapiens] 55 2e-07
gi|169205732 PREDICTED: hypothetical protein [Homo sapiens] 55 2e-07
gi|57864582 hornerin [Homo sapiens] 52 2e-06
gi|62122917 filaggrin family member 2 [Homo sapiens] 52 2e-06
gi|239750846 PREDICTED: hypothetical protein [Homo sapiens] 50 5e-06
gi|239745208 PREDICTED: hypothetical protein XP_002343389 [Homo ... 50 5e-06
gi|239756319 PREDICTED: hypothetical protein [Homo sapiens] 50 6e-06
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s... 49 8e-06
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s... 49 8e-06
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s... 49 8e-06
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap... 49 8e-06
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 49 1e-05
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 49 1e-05
gi|56699482 hypothetical protein LOC25940 [Homo sapiens] 49 1e-05
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 48 2e-05
gi|28875797 small protein rich in arginine and glycine [Homo sap... 47 3e-05
gi|169171347 PREDICTED: hypothetical protein [Homo sapiens] 47 4e-05
gi|169172209 PREDICTED: hypothetical protein [Homo sapiens] 47 4e-05
gi|169170953 PREDICTED: hypothetical protein [Homo sapiens] 47 4e-05
gi|239508753 PREDICTED: hypothetical protein [Homo sapiens] 47 4e-05
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 47 5e-05
gi|239749709 PREDICTED: hypothetical protein [Homo sapiens] 47 5e-05
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 46 7e-05
gi|60097902 filaggrin [Homo sapiens] 45 1e-04
gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 45 2e-04
gi|186928825 dermokine isoform 3 precursor [Homo sapiens] 45 2e-04
gi|156616290 collagen type VI alpha 6 [Homo sapiens] 45 2e-04
>gi|239750438 PREDICTED: hypothetical protein [Homo sapiens]
Length = 510
Score = 1046 bits (2705), Expect = 0.0
Identities = 510/510 (100%), Positives = 510/510 (100%)
Query: 1 MDGASQARSDCWGILLAFSPSQTHWCKKVFSTWIRQIDVKTEGELKTKNIRTCRAYFWSD 60
MDGASQARSDCWGILLAFSPSQTHWCKKVFSTWIRQIDVKTEGELKTKNIRTCRAYFWSD
Sbjct: 1 MDGASQARSDCWGILLAFSPSQTHWCKKVFSTWIRQIDVKTEGELKTKNIRTCRAYFWSD 60
Query: 61 SDVSGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVE 120
SDVSGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVE
Sbjct: 61 SDVSGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVE 120
Query: 121 FRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGV 180
FRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGV
Sbjct: 121 FRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGV 180
Query: 181 QIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRP 240
QIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRP
Sbjct: 181 QIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRP 240
Query: 241 GQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEE 300
GQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEE
Sbjct: 241 GQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEE 300
Query: 301 LLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALL 360
LLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALL
Sbjct: 301 LLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALL 360
Query: 361 RAQAASAGRDGGGAMASGIYQRAGIAIEHKPGCLCSTEKFCLFGREPRMQTKCKTHADAQ 420
RAQAASAGRDGGGAMASGIYQRAGIAIEHKPGCLCSTEKFCLFGREPRMQTKCKTHADAQ
Sbjct: 361 RAQAASAGRDGGGAMASGIYQRAGIAIEHKPGCLCSTEKFCLFGREPRMQTKCKTHADAQ 420
Query: 421 FFSLQVHLGVVLHLFFGLHGLQRPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERR 480
FFSLQVHLGVVLHLFFGLHGLQRPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERR
Sbjct: 421 FFSLQVHLGVVLHLFFGLHGLQRPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERR 480
Query: 481 RAVGRQRQRGEERRLVTQHRAHGEVRRPVR 510
RAVGRQRQRGEERRLVTQHRAHGEVRRPVR
Sbjct: 481 RAVGRQRQRGEERRLVTQHRAHGEVRRPVR 510
>gi|239744740 PREDICTED: hypothetical protein XP_002343259 [Homo
sapiens]
Length = 457
Score = 776 bits (2003), Expect = 0.0
Identities = 408/510 (80%), Positives = 413/510 (80%), Gaps = 67/510 (13%)
Query: 1 MDGASQARSDCWGILLAFSPSQTHWCKKVFSTWIRQIDVKTEGELKTKNIRTCRAYFWSD 60
MDGASQARSDCWGILLAFSPSQTHWCKKVFSTWIRQIDVKTEGELKTKNIRTCRAYFWSD
Sbjct: 1 MDGASQARSDCWGILLAFSPSQTHWCKKVFSTWIRQIDVKTEGELKTKNIRTCRAYFWSD 60
Query: 61 SDVSGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVE 120
SDVSGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVE
Sbjct: 61 SDVSGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVE 120
Query: 121 FRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGV 180
FRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGV
Sbjct: 121 FRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGV 180
Query: 181 QIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRP 240
QIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRP
Sbjct: 181 QIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRP 240
Query: 241 GQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEE 300
GQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEE
Sbjct: 241 GQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEE 300
Query: 301 LLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALL 360
LLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALL
Sbjct: 301 LLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALL 360
Query: 361 RAQAASAGRDGGGAMASGIYQRAGIAIEHKPGCLCSTEKFCLFGREPRMQTKCKTHADAQ 420
RAQAASAGRDGGGAMA R G E+ GR
Sbjct: 361 RAQAASAGRDGGGAMAP--QMRLGPQ---------GGERDAGLGRP-------------- 395
Query: 421 FFSLQVHLGVVLHLFFGLHGLQRPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERR 480
H L ++ G + ER +GR Q R ERR
Sbjct: 396 ------------------HQLIHDRLGQGARQRERRRAVGRQRQ----------RGEERR 427
Query: 481 RAVGRQRQRGEERRLVTQHRAHGEVRRPVR 510
LVTQHRAHGEVRRP R
Sbjct: 428 --------------LVTQHRAHGEVRRPKR 443
>gi|239755920 PREDICTED: hypothetical protein XP_002344746 [Homo
sapiens]
Length = 600
Score = 768 bits (1982), Expect = 0.0
Identities = 404/506 (79%), Positives = 409/506 (80%), Gaps = 67/506 (13%)
Query: 5 SQARSDCWGILLAFSPSQTHWCKKVFSTWIRQIDVKTEGELKTKNIRTCRAYFWSDSDVS 64
SQARSDCWGILLAFSPSQTHWCKKVFSTWIRQIDVKTEGELKTKNIRTCRAYFWSDSDVS
Sbjct: 148 SQARSDCWGILLAFSPSQTHWCKKVFSTWIRQIDVKTEGELKTKNIRTCRAYFWSDSDVS 207
Query: 65 GTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFRAR 124
GTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFRAR
Sbjct: 208 GTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFRAR 267
Query: 125 VHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEE 184
VHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEE
Sbjct: 268 VHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEE 327
Query: 185 GVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 244
GVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL
Sbjct: 328 GVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 387
Query: 245 RRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLAR 304
RRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLAR
Sbjct: 388 RRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLAR 447
Query: 305 QARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQA 364
QARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQA
Sbjct: 448 QARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQA 507
Query: 365 ASAGRDGGGAMASGIYQRAGIAIEHKPGCLCSTEKFCLFGREPRMQTKCKTHADAQFFSL 424
ASAGRDGGGAMA R G E+ GR
Sbjct: 508 ASAGRDGGGAMAP--QMRLGPQ---------GGERDAGLGRP------------------ 538
Query: 425 QVHLGVVLHLFFGLHGLQRPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERRRAVG 484
H L ++ G + ER +GR Q R ERR
Sbjct: 539 --------------HQLIHDRLGQGARQRERRRAVGRQRQ----------RGEERR---- 570
Query: 485 RQRQRGEERRLVTQHRAHGEVRRPVR 510
LVTQHRAHGEVRRP R
Sbjct: 571 ----------LVTQHRAHGEVRRPKR 586
>gi|239750574 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1297
Score = 55.1 bits (131), Expect = 2e-07
Identities = 110/400 (27%), Positives = 135/400 (33%), Gaps = 62/400 (15%)
Query: 104 GRQGHGAGG-ERGGAAVEFRARVHCHRGRAGGQGGDFAVQ-----GPRGRR------HGG 151
GR+G AGG ERGG R R RGR G V G G R H G
Sbjct: 360 GRRGRAAGGQERGGRG---RRRQQGRRGRRQAGPGLAKVDVDVLAGALGLRWQWVLVHAG 416
Query: 152 QGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCR----RGGGRRCGHVRV 207
Q G R HR A RA + G +R G R G GR G R
Sbjct: 417 QAGQPLQGQARGPHRPAALAQEALRAAAAR-PHGRRHYRVRGLRGAGPEGAGRLAGPWR- 474
Query: 208 GVREQA---SERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGP 264
G+R Q + HG A + VL+ V G G G G+G A G
Sbjct: 475 GLRLQTLLLQDAPHGGA--HEHVLVAVPATGVGGLVGA---------GQGAVA--AAGNA 521
Query: 265 RNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPV-EELLARQARGEAEARQGA-----LG 318
R G G G GA ++AG E VPV ++L G+ A LG
Sbjct: 522 PERLPAGVQGCGEEVGRGARGDRVAGGHVEVVPVGQQLAICMLHGQLGTAPHAHVPTVLG 581
Query: 319 QVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQAASAGRDG-----GG 373
GGR GL+A R RR R P G G GG
Sbjct: 582 GALGGRA--------GLVAAPARRECPARRRGGCWPRRPRRRHGGGGGGGGPGLQDLLGG 633
Query: 374 AMASGIYQRAGIAIEHKPGCLCSTEKFCLFGREPRMQTKCKTHADAQFFSLQVHLGVVLH 433
A G + +A P T + GR + C A + + VV
Sbjct: 634 GHAGGAHGHVVVA----PAAAAPTAREGRAGRHGHVAVVCPQVAAGAPVGADLDVSVV-- 687
Query: 434 LFFGLHGLQRPQMRLGPQGGERDAGLGRPHQLIHDRLGQG 473
L+ G+ G G R A G PHQ + + G+G
Sbjct: 688 LWVGVVGHLGRGRGAGRAEAARAAREGGPHQGVFIQRGRG 727
Score = 48.5 bits (114), Expect = 1e-05
Identities = 83/286 (29%), Positives = 105/286 (36%), Gaps = 45/286 (15%)
Query: 69 RGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGH----GAGGERGGAAVEFRAR 124
RGR AG +AA + G +F++ G GH G G+ G + +
Sbjct: 698 RGRGAGRA----EAARAAREGGPHQG--VFIQRGRGGLGHRPLPGWRGQGVGPLAQPSVQ 751
Query: 125 VHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAV----RDRHRDGVGAVAQPRAHGV 180
V R G QGP G E TAA R R RDG+G VA A G
Sbjct: 752 VLGRVPRDPAVGAATVAQGPVH----GHVPVELTAAAAVSGRGRLRDGLGRVASVAAEGA 807
Query: 181 QIEEGVAV----HRAG--GCRRGGGRRCGHVRVGV----REQASERGHGQALGGQDVLLE 230
Q+ AV H AG G RGGG G G Q R + +G + V
Sbjct: 808 QVAWAGAVLVQGHEAGVAGGARGGGAAAGGPLAGAVVQRMRQRRVRAGRRRVGARAV--A 865
Query: 231 VEGQGGRGRPGQSLR-RSGRGHGRGI-------QARDTGGGPRNRGQEGTHA----SGRH 278
G+ G G G R R G GHG + Q R +G A + R
Sbjct: 866 AAGRQGAGAGGGGRRVRHGHGHGAAVLQRAPCRQQRHLAPAAAAAAAQGVRAAQGRAHRP 925
Query: 279 AGEGAP-HGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGG 323
+GAP H G + R +A G A + ALG+ RGG
Sbjct: 926 GAQGAPSHRHRPGARGRRSRRRAAVA--LAGGAHPARAALGRRRGG 969
Score = 44.3 bits (103), Expect = 3e-04
Identities = 94/325 (28%), Positives = 111/325 (34%), Gaps = 72/325 (22%)
Query: 111 GGERGGAA--VEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDG 168
GG GG A V AR C R GG + PR RRHGG GGG +D
Sbjct: 581 GGALGGRAGLVAAPARRECPARRRGGCWP----RRPR-RRHGGGGGGGGPGL-----QDL 630
Query: 169 VGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVL 228
+G AHG + A A R G R GHV V + A+ G L VL
Sbjct: 631 LGGGHAGGAHGHVVVAPAAA--APTAREGRAGRHGHVAVVCPQVAAGAPVGADLDVSVVL 688
Query: 229 -LEVEGQGGRGR------PGQSLRRSGRGHGRGIQARDTGG-------GPRNRG-----Q 269
+ V G GRGR ++ R G G IQ R GG G R +G Q
Sbjct: 689 WVGVVGHLGRGRGAGRAEAARAAREGGPHQGVFIQ-RGRGGLGHRPLPGWRGQGVGPLAQ 747
Query: 270 EGTHASGR----------HAGEGAPHGKL------AGVQEERVPVEELLARQARGEAEAR 313
GR +G HG + A R + + L R A AE
Sbjct: 748 PSVQVLGRVPRDPAVGAATVAQGPVHGHVPVELTAAAAVSGRGRLRDGLGRVASVAAEGA 807
Query: 314 Q--------------GALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPAL 359
Q G G RGG ++ R R R GRR A
Sbjct: 808 QVAWAGAVLVQGHEAGVAGGARGGGAAAGGPLAGAVVQRMRQRRVRAGRRRVGAR----- 862
Query: 360 LRAQAASAGRDGGGAMASGIYQRAG 384
A+AGR G GA G R G
Sbjct: 863 ---AVAAAGRQGAGAGGGGRRVRHG 884
Score = 41.2 bits (95), Expect = 0.002
Identities = 48/150 (32%), Positives = 58/150 (38%), Gaps = 15/150 (10%)
Query: 94 GGRLFLRAEFGRQGHGAGGERGGAAVEFRA-RVHCHRGRAGGQGGDFAVQGPRGRRHGGQ 152
G + RA +Q H A AA RA + HR A G G RGRR +
Sbjct: 888 GAAVLQRAPCRQQRHLAPAAAAAAAQGVRAAQGRAHRPGAQGAPSHRHRPGARGRRSRRR 947
Query: 153 ------GGGEQTAAVRDRHRDGVGAVAQPRAH-----GVQIEEGVAVHRAGGCRRGGGRR 201
GG A R R G AV AH G Q+++ V RAG GRR
Sbjct: 948 AAVALAGGAHPARAALGRRRGGGQAVGARAAHQARLAGGQVDQVVVAARAGDADGVRGRR 1007
Query: 202 CGHVRVGVR---EQASERGHGQALGGQDVL 228
+ + R E+ ER HG G DVL
Sbjct: 1008 PRRLALTARPELEELLERLHGLQDGLVDVL 1037
Score = 32.7 bits (73), Expect = 0.80
Identities = 63/212 (29%), Positives = 80/212 (37%), Gaps = 19/212 (8%)
Query: 65 GTGLRGRAAGPVRLGFQA---ANQPLDALQFAGGR-LFLRAEFGRQGHGAGGERGGAAVE 120
G GR+ P R QA P AL+ GR L L GR + + A
Sbjct: 183 GLSAHGRSTAP-RTTDQAPGLTRGPRPALRCQRGRRLQLSWGGGRLVAPSRADTHAALAA 241
Query: 121 FRARVHCHRGRAGGQGGDFAVQGPRG-RRHGGQGGGEQTAAVRDRH-RDGVGAVAQPRAH 178
F R H GR G +G G RR GG+G G AA R D +GA R
Sbjct: 242 FPERDIFHGGRVVALGVVGEGRGHGGDRRGGGEGLGTVAAAAPLRVCADDLGAAVGVRGL 301
Query: 179 GVQIEEGV----AVHRAGGCRRGGGRRCGHVRV----GVREQASERGHGQALGGQDVLLE 230
++EG+ +H A RR GH G R++ RG G V+
Sbjct: 302 A-GLQEGLDSRHLLHEAQPLH--ARRRAGHAGSFWLRGGRDRL-RRGGGHTKSHLGVVTI 357
Query: 231 VEGQGGRGRPGQSLRRSGRGHGRGIQARDTGG 262
V G+ GR GQ GR +G + R G
Sbjct: 358 VPGRRGRAAGGQERGGRGRRRQQGRRGRRQAG 389
>gi|169205732 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1297
Score = 55.1 bits (131), Expect = 2e-07
Identities = 110/400 (27%), Positives = 135/400 (33%), Gaps = 62/400 (15%)
Query: 104 GRQGHGAGG-ERGGAAVEFRARVHCHRGRAGGQGGDFAVQ-----GPRGRR------HGG 151
GR+G AGG ERGG R R RGR G V G G R H G
Sbjct: 360 GRRGRAAGGQERGGRG---RRRQQGRRGRRQAGPGLAKVDVDVLAGALGLRWQWVLVHAG 416
Query: 152 QGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCR----RGGGRRCGHVRV 207
Q G R HR A RA + G +R G R G GR G R
Sbjct: 417 QAGQPLQGQARGPHRPAALAQEALRAAAAR-PHGRRHYRVRGLRGAGPEGAGRLAGPWR- 474
Query: 208 GVREQA---SERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGP 264
G+R Q + HG A + VL+ V G G G G+G A G
Sbjct: 475 GLRLQTLLLQDAPHGGA--HEHVLVAVPATGVGGLVGA---------GQGAVA--AAGNA 521
Query: 265 RNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPV-EELLARQARGEAEARQGA-----LG 318
R G G G GA ++AG E VPV ++L G+ A LG
Sbjct: 522 PERLPAGVQGCGEEVGRGARGDRVAGGHVEVVPVGQQLAICMLHGQLGTAPHAHVPTVLG 581
Query: 319 QVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQAASAGRDG-----GG 373
GGR GL+A R RR R P G G GG
Sbjct: 582 GALGGRA--------GLVAAPARRECPARRRGGCWPRRPRRRHGGGGGGGGPGLQDLLGG 633
Query: 374 AMASGIYQRAGIAIEHKPGCLCSTEKFCLFGREPRMQTKCKTHADAQFFSLQVHLGVVLH 433
A G + +A P T + GR + C A + + VV
Sbjct: 634 GHAGGAHGHVVVA----PAAAAPTAREGRAGRHGHVAVVCPQVAAGAPVGADLDVSVV-- 687
Query: 434 LFFGLHGLQRPQMRLGPQGGERDAGLGRPHQLIHDRLGQG 473
L+ G+ G G R A G PHQ + + G+G
Sbjct: 688 LWVGVVGHLGRGRGAGRAEAARAAREGGPHQGVFIQRGRG 727
Score = 48.5 bits (114), Expect = 1e-05
Identities = 83/286 (29%), Positives = 105/286 (36%), Gaps = 45/286 (15%)
Query: 69 RGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGH----GAGGERGGAAVEFRAR 124
RGR AG +AA + G +F++ G GH G G+ G + +
Sbjct: 698 RGRGAGRA----EAARAAREGGPHQG--VFIQRGRGGLGHRPLPGWRGQGVGPLAQPSVQ 751
Query: 125 VHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAV----RDRHRDGVGAVAQPRAHGV 180
V R G QGP G E TAA R R RDG+G VA A G
Sbjct: 752 VLGRVPRDPAVGAATVAQGPVH----GHVPVELTAAAAVSGRGRLRDGLGRVASVAAEGA 807
Query: 181 QIEEGVAV----HRAG--GCRRGGGRRCGHVRVGV----REQASERGHGQALGGQDVLLE 230
Q+ AV H AG G RGGG G G Q R + +G + V
Sbjct: 808 QVAWAGAVLVQGHEAGVAGGARGGGAAAGGPLAGAVVQRMRQRRVRAGRRRVGARAV--A 865
Query: 231 VEGQGGRGRPGQSLR-RSGRGHGRGI-------QARDTGGGPRNRGQEGTHA----SGRH 278
G+ G G G R R G GHG + Q R +G A + R
Sbjct: 866 AAGRQGAGAGGGGRRVRHGHGHGAAVLQRAPCRQQRHLAPAAAAAAAQGVRAAQGRAHRP 925
Query: 279 AGEGAP-HGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGG 323
+GAP H G + R +A G A + ALG+ RGG
Sbjct: 926 GAQGAPSHRHRPGARGRRSRRRAAVA--LAGGAHPARAALGRRRGG 969
Score = 44.3 bits (103), Expect = 3e-04
Identities = 94/325 (28%), Positives = 111/325 (34%), Gaps = 72/325 (22%)
Query: 111 GGERGGAA--VEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDG 168
GG GG A V AR C R GG + PR RRHGG GGG +D
Sbjct: 581 GGALGGRAGLVAAPARRECPARRRGGCWP----RRPR-RRHGGGGGGGGPGL-----QDL 630
Query: 169 VGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVL 228
+G AHG + A A R G R GHV V + A+ G L VL
Sbjct: 631 LGGGHAGGAHGHVVVAPAAA--APTAREGRAGRHGHVAVVCPQVAAGAPVGADLDVSVVL 688
Query: 229 -LEVEGQGGRGR------PGQSLRRSGRGHGRGIQARDTGG-------GPRNRG-----Q 269
+ V G GRGR ++ R G G IQ R GG G R +G Q
Sbjct: 689 WVGVVGHLGRGRGAGRAEAARAAREGGPHQGVFIQ-RGRGGLGHRPLPGWRGQGVGPLAQ 747
Query: 270 EGTHASGR----------HAGEGAPHGKL------AGVQEERVPVEELLARQARGEAEAR 313
GR +G HG + A R + + L R A AE
Sbjct: 748 PSVQVLGRVPRDPAVGAATVAQGPVHGHVPVELTAAAAVSGRGRLRDGLGRVASVAAEGA 807
Query: 314 Q--------------GALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPAL 359
Q G G RGG ++ R R R GRR A
Sbjct: 808 QVAWAGAVLVQGHEAGVAGGARGGGAAAGGPLAGAVVQRMRQRRVRAGRRRVGAR----- 862
Query: 360 LRAQAASAGRDGGGAMASGIYQRAG 384
A+AGR G GA G R G
Sbjct: 863 ---AVAAAGRQGAGAGGGGRRVRHG 884
Score = 41.2 bits (95), Expect = 0.002
Identities = 48/150 (32%), Positives = 58/150 (38%), Gaps = 15/150 (10%)
Query: 94 GGRLFLRAEFGRQGHGAGGERGGAAVEFRA-RVHCHRGRAGGQGGDFAVQGPRGRRHGGQ 152
G + RA +Q H A AA RA + HR A G G RGRR +
Sbjct: 888 GAAVLQRAPCRQQRHLAPAAAAAAAQGVRAAQGRAHRPGAQGAPSHRHRPGARGRRSRRR 947
Query: 153 ------GGGEQTAAVRDRHRDGVGAVAQPRAH-----GVQIEEGVAVHRAGGCRRGGGRR 201
GG A R R G AV AH G Q+++ V RAG GRR
Sbjct: 948 AAVALAGGAHPARAALGRRRGGGQAVGARAAHQARLAGGQVDQVVVAARAGDADGVRGRR 1007
Query: 202 CGHVRVGVR---EQASERGHGQALGGQDVL 228
+ + R E+ ER HG G DVL
Sbjct: 1008 PRRLALTARPELEELLERLHGLQDGLVDVL 1037
Score = 32.7 bits (73), Expect = 0.80
Identities = 63/212 (29%), Positives = 80/212 (37%), Gaps = 19/212 (8%)
Query: 65 GTGLRGRAAGPVRLGFQA---ANQPLDALQFAGGR-LFLRAEFGRQGHGAGGERGGAAVE 120
G GR+ P R QA P AL+ GR L L GR + + A
Sbjct: 183 GLSAHGRSTAP-RTTDQAPGLTRGPRPALRCQRGRRLQLSWGGGRLVAPSRADTHAALAA 241
Query: 121 FRARVHCHRGRAGGQGGDFAVQGPRG-RRHGGQGGGEQTAAVRDRH-RDGVGAVAQPRAH 178
F R H GR G +G G RR GG+G G AA R D +GA R
Sbjct: 242 FPERDIFHGGRVVALGVVGEGRGHGGDRRGGGEGLGTVAAAAPLRVCADDLGAAVGVRGL 301
Query: 179 GVQIEEGV----AVHRAGGCRRGGGRRCGHVRV----GVREQASERGHGQALGGQDVLLE 230
++EG+ +H A RR GH G R++ RG G V+
Sbjct: 302 A-GLQEGLDSRHLLHEAQPLH--ARRRAGHAGSFWLRGGRDRL-RRGGGHTKSHLGVVTI 357
Query: 231 VEGQGGRGRPGQSLRRSGRGHGRGIQARDTGG 262
V G+ GR GQ GR +G + R G
Sbjct: 358 VPGRRGRAAGGQERGGRGRRRQQGRRGRRQAG 389
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 51.6 bits (122), Expect = 2e-06
Identities = 72/289 (24%), Positives = 99/289 (34%), Gaps = 57/289 (19%)
Query: 103 FGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVR 162
+GRQG G+G G GQ G + Q P RHG G ++
Sbjct: 2525 YGRQGSGSGQSPG-----------------HGQRGSGSRQSPSYGRHGSGSGRSSSSG-- 2565
Query: 163 DRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG--HGQ 220
+H G+G + H + + + G G G G+ + G R S RG HG
Sbjct: 2566 -QHGSGLGESSGFGHHESSSGQSSSYSQHGS---GSGHSSGYGQHGSRSGQSSRGERHGS 2621
Query: 221 ALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASG-RHA 279
+ G GQ G G R GHGR G G G H SG H+
Sbjct: 2622 SSGSSSHY----GQHGSG------SRQSSGHGR------QGSGSGQSPSRGRHGSGLGHS 2665
Query: 280 GEGAPHGKLAGVQEERVPVEELLARQA-RGEAEARQG---ALGQVRGGRVRLHRERREGL 335
HG +G R P E L + G+ E+ G A Q G + + G
Sbjct: 2666 SSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGS 2725
Query: 336 LARERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMASGIYQRAG 384
+ + + G Q++S G G G+ S Y R G
Sbjct: 2726 TSGQSSTFDQEGSS-----------TGQSSSYGHRGSGSSQSSGYGRHG 2763
Score = 50.4 bits (119), Expect = 4e-06
Identities = 72/296 (24%), Positives = 100/296 (33%), Gaps = 57/296 (19%)
Query: 103 FGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVR 162
+GRQG G+G G GQ G + Q P RHG G ++
Sbjct: 1115 YGRQGSGSGQSPG-----------------HGQRGSGSRQSPSYGRHGSGSGRSSSSG-- 1155
Query: 163 DRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG--HGQ 220
+H G+G + H + + + G G G G+ + G R S RG HG
Sbjct: 1156 -QHGSGLGESSGFGHHESSSGQSSSYSQHGS---GSGHSSGYGQHGSRSGQSSRGERHGS 1211
Query: 221 ALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASG-RHA 279
+ G GQ G G R GHGR G G + G H SG H+
Sbjct: 1212 SSGSSSHY----GQHGSG------SRQSSGHGR------QGSGSGHSPSRGRHGSGLGHS 1255
Query: 280 GEGAPHGKLAGVQEERVPVEELLARQA-RGEAEARQG---ALGQVRGGRVRLHRERREGL 335
HG +G R P E + G+ E+ G A Q G + + G
Sbjct: 1256 SSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGS 1315
Query: 336 LARERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMASGIYQRAGIAIEHKP 391
+ + + G Q++S G G G+ S Y R G P
Sbjct: 1316 TSGQSSTFDQEGSS-----------TGQSSSYGHRGSGSSQSSGYGRHGAGSGQSP 1360
Score = 50.4 bits (119), Expect = 4e-06
Identities = 71/296 (23%), Positives = 101/296 (34%), Gaps = 57/296 (19%)
Query: 103 FGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVR 162
+GRQG G+G G GQ G + Q P RHG G ++
Sbjct: 2055 YGRQGSGSGQSPG-----------------HGQRGSGSRQSPSYGRHGSGSGRSSSSG-- 2095
Query: 163 DRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG--HGQ 220
+H G+G + H + + + G G G G+ + G R S RG HG
Sbjct: 2096 -QHGPGLGESSGFGHHESSSGQSSSYSQHGS---GSGHSSGYGQHGSRSGQSSRGERHGS 2151
Query: 221 ALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGR-HA 279
+ G GQ G G R GHGR G G + G H SG H+
Sbjct: 2152 SSGSSSRY----GQHGSG------SRQSSGHGR------QGSGSGHSPSRGRHGSGSGHS 2195
Query: 280 GEGAPHGKLAGVQEERVPVEELLARQA-RGEAEARQG---ALGQVRGGRVRLHRERREGL 335
HG +G R P E + G+ E+ G A Q G + + G
Sbjct: 2196 SSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGS 2255
Query: 336 LARERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMASGIYQRAGIAIEHKP 391
+ + + G Q++S G+ G G+ S Y + G P
Sbjct: 2256 TSGQSSTFDQEGSS-----------TGQSSSHGQHGSGSSQSSSYGQQGSGSGQSP 2300
Score = 47.0 bits (110), Expect = 4e-05
Identities = 69/294 (23%), Positives = 98/294 (33%), Gaps = 53/294 (18%)
Query: 103 FGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVR 162
+GRQG G+G G GQ G + Q P RHG G ++
Sbjct: 1585 YGRQGSGSGQSPG-----------------HGQRGSGSRQSPSYGRHGSGSGRSSSSG-- 1625
Query: 163 DRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQAL 222
+H G+G + H + + + G G G G+ + G R S R G+
Sbjct: 1626 -QHGSGLGESSGFGHHESSSGQSSSYSQHGS---GSGHSSGYGQHGSRSGQSSR--GERH 1679
Query: 223 GGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASG-RHAGE 281
G GQ G G R GHGR G G G H SG H+
Sbjct: 1680 GSSSRSSSRYGQHGSG------SRQSSGHGR------QGSGSGQSPSRGRHGSGLGHSSS 1727
Query: 282 GAPHGKLAGVQEERVPVEELLARQA-RGEAEARQG---ALGQVRGGRVRLHRERREGLLA 337
HG +G R P E + G+ E+ G A Q G + + G +
Sbjct: 1728 HGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS 1787
Query: 338 RERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMASGIYQRAGIAIEHKP 391
+ + G Q++S G+ G G+ S Y + G P
Sbjct: 1788 GQSSTFDQEGSS-----------TGQSSSHGQHGSGSSQSSSYGQQGSGSGQSP 1830
Score = 43.9 bits (102), Expect = 3e-04
Identities = 71/297 (23%), Positives = 101/297 (34%), Gaps = 39/297 (13%)
Query: 108 HGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRD 167
HG+ + + + + GR GQ + Q P HG +G G + +H
Sbjct: 390 HGSSSRQSSSYGQHESASRHSSGR--GQHSSGSGQSPG---HGQRGSGSGQSPSSGQHGT 444
Query: 168 GVGAVAQPRAH--------GVQIEEGVAVHRAGGCRRGGG--RRCGHVRVGVREQASERG 217
G G + + G E + H +G + G G GH + G R S RG
Sbjct: 445 GFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRG 504
Query: 218 HGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASG- 276
Q G GQ G G R GH R +G G G H SG
Sbjct: 505 ERQ--GSSAGSSSSYGQHGSGS------RQSLGHSR----HGSGSGQSPSPSRGRHESGS 552
Query: 277 RHAGEGAPHGKLAGVQEERVPVEELLARQA-RGEAEARQG-ALGQVRGGRVRLHRERREG 334
R + PHG +G R P E + G E+R G + G + G H G
Sbjct: 553 RQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGH-SSTHG 611
Query: 335 LLARERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMASGIYQRAGIAIEHKP 391
+ G+ A + Q++S G+ G G+ S Y + G P
Sbjct: 612 QHGSTSGQSSSCGQHGATS--------GQSSSHGQHGSGSSQSSRYGQQGSGSGQSP 660
Score = 42.4 bits (98), Expect = 0.001
Identities = 54/198 (27%), Positives = 71/198 (35%), Gaps = 27/198 (13%)
Query: 107 GHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRR---HGGQGGGEQTAAVRD 163
G+G G R G + R H G + G + G R+ HG QG G + R
Sbjct: 1192 GYGQHGSRSGQSS--RGERH---GSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRG 1246
Query: 164 RHRDGVGAVAQPRAHGV----QIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQ-ASERGH 218
RH G+G + HG G R+G G G Q S GH
Sbjct: 1247 RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 1306
Query: 219 ----GQ--ALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGT 272
GQ + GQ + EG GQS RG G ++ +G G G +
Sbjct: 1307 FCSQGQHGSTSGQSSTFDQEGSS----TGQSSSYGHRGSG---SSQSSGYGRHGAGSGQS 1359
Query: 273 HASGRHAGEGAPHGKLAG 290
+ GRH G G+ H G
Sbjct: 1360 PSRGRH-GSGSGHSSSYG 1376
Score = 42.0 bits (97), Expect = 0.001
Identities = 52/198 (26%), Positives = 67/198 (33%), Gaps = 20/198 (10%)
Query: 107 GHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHR 166
G+G G R G + R H R+ + G + HG QG G + R RH
Sbjct: 1662 GYGQHGSRSGQSS--RGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHG 1719
Query: 167 DGVGAVAQPRAHGV----QIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQ-ASERGH--- 218
G+G + HG G R+G G G Q S GH
Sbjct: 1720 SGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCS 1779
Query: 219 -GQ--ALGGQDVLLEVEGQ--GGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTH 273
GQ + GQ + EG G GQ S + G Q +G P G H
Sbjct: 1780 QGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSP----SRGRH 1835
Query: 274 ASGR-HAGEGAPHGKLAG 290
SG H+ HG +G
Sbjct: 1836 GSGSGHSSSYGQHGSGSG 1853
Score = 41.2 bits (95), Expect = 0.002
Identities = 69/314 (21%), Positives = 96/314 (30%), Gaps = 39/314 (12%)
Query: 107 GHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRR---HG--GQGGGEQTAAV 161
GH + E+ G+ +R H G + G + G R+ HG G G G+ +
Sbjct: 1422 GHSSSYEQHGSRSGQSSRGERH-GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS 1480
Query: 162 RDRHRDGVGAVAQ--PRAHGVQIEEGVAVHRAGGCRRGG-----------------GRRC 202
R RH G G + P G + +G G G
Sbjct: 1481 RGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSS 1540
Query: 203 GHVRV-----GVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQA 257
GH Q+S G A GQ G G G + SG G G
Sbjct: 1541 GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 1600
Query: 258 RDTGGGPRNRGQEGTHASG-----RHAGEGAPHGKLAGVQEERVPVEELLARQARGEAEA 312
R G G R G H SG G+ G+ +G + + G
Sbjct: 1601 R--GSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG 1658
Query: 313 RQGALGQVRGGRVRLHRERREGLLARERARL--FHLGRRCALANRAPALLRAQAASAGRD 370
GQ + R R G +R +R G R + + Q+ S GR
Sbjct: 1659 HSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRH 1718
Query: 371 GGGAMASGIYQRAG 384
G G S + + G
Sbjct: 1719 GSGLGHSSSHGQHG 1732
Score = 40.8 bits (94), Expect = 0.003
Identities = 53/210 (25%), Positives = 68/210 (32%), Gaps = 31/210 (14%)
Query: 107 GHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRR---HGGQGGGEQTAAVRD 163
G+G G R G + R H G + G + G R+ HG QG G + R
Sbjct: 2602 GYGQHGSRSGQSS--RGERH---GSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRG 2656
Query: 164 RHRDGVGAVAQPRAHGV----QIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQ-ASERGH 218
RH G+G + HG G R G G G Q S GH
Sbjct: 2657 RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGH 2716
Query: 219 ----GQ--ALGGQDVLLEVEG-----------QGGRGRPGQSLRRSGRGHGRGIQARDTG 261
GQ + GQ + EG +G R G G G+ + G
Sbjct: 2717 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHG 2776
Query: 262 GGPRNRGQEGTHASGRHAGEG-APHGKLAG 290
G G H SG G + HG +G
Sbjct: 2777 SGSGQSSSYGQHGSGSGQSSGYSQHGSGSG 2806
Score = 40.4 bits (93), Expect = 0.004
Identities = 75/318 (23%), Positives = 110/318 (34%), Gaps = 45/318 (14%)
Query: 103 FGRQGHGAG-----GERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRR---HGGQGG 154
+ + G G+G G+ G + + + G + GQ + +G + +G G
Sbjct: 1297 YSQHGSGSGHFCSQGQHGSTSGQ--SSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGA 1354
Query: 155 GEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQAS 214
G + R RH G G + HG + R G G G+ G G E +S
Sbjct: 1355 GSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS---GSGQSSGF---GHHESSS 1408
Query: 215 ERGHGQALGGQDVLLEVEGQGGRGRPGQSLR--RSGRGHGRGIQARDTGGGPRNRGQEGT 272
+ G G + R GQS R R G G G G R G
Sbjct: 1409 WQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQ 1468
Query: 273 HAS----------GRH-AGEG-----APHGKLAGVQEERVPVEELLARQA-RGEAEARQG 315
H S GRH +G G +P+G +G R P E + + G E+R G
Sbjct: 1469 HGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSG 1528
Query: 316 -ALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQAASAGRDGGGA 374
+ G + G H G + G+ A + Q++S G+ G G+
Sbjct: 1529 QSSGYGQHGSSSGH-SSTHGQHGSTSGQSSSCGQHGASS--------GQSSSHGQHGSGS 1579
Query: 375 MASGIYQRAGIAIEHKPG 392
S Y R G PG
Sbjct: 1580 SQSSGYGRQGSGSGQSPG 1597
Score = 40.0 bits (92), Expect = 0.005
Identities = 48/194 (24%), Positives = 67/194 (34%), Gaps = 29/194 (14%)
Query: 96 RLFLRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGG 155
RL + +F Q + G+ + H+ GQ G + Q P +G G G
Sbjct: 158 RLSFQRDFSGQHNSYSGQSSSYGEQ---NSDSHQSSGRGQCGSGSGQSP---NYGQHGSG 211
Query: 156 EQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASE 215
++ D H G G + H + + G G G G+ + G R S
Sbjct: 212 SGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGS---GSGHSSGYGQHGSRSGQSS 268
Query: 216 RG--HGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTH 273
RG H + G GQ G G R GHGR G G R H
Sbjct: 269 RGERHRSSSGSSSSY----GQHGSG------SRQSLGHGR------QGSGSRQSPSHVRH 312
Query: 274 ASGRHAGEGAPHGK 287
SG +G + HG+
Sbjct: 313 GSG--SGHSSSHGQ 324
Score = 40.0 bits (92), Expect = 0.005
Identities = 46/195 (23%), Positives = 65/195 (33%), Gaps = 31/195 (15%)
Query: 107 GHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRR---HGGQGGGEQTAAVRD 163
G+G G R G + +R HR + G + G R+ HG QG G + +
Sbjct: 256 GYGQHGSRSGQS----SRGERHRS-SSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHV 310
Query: 164 RHRDGVGAVAQPRAHGVQIE---------------EGVAVHRAGGCRRGGGRRCGHVRVG 208
RH G G + HG G H +G + G + G G
Sbjct: 311 RHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGS---G 367
Query: 209 VREQASERGHGQALG-----GQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGG 263
+S+ HG G GQ + S SGRG + G G
Sbjct: 368 SGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHG 427
Query: 264 PRNRGQEGTHASGRH 278
R G + +SG+H
Sbjct: 428 QRGSGSGQSPSSGQH 442
Score = 39.7 bits (91), Expect = 0.007
Identities = 49/205 (23%), Positives = 64/205 (31%), Gaps = 24/205 (11%)
Query: 105 RQGHGAGGERGGAAVEFRARVHCH-----RGRAGGQGGDFAVQGPRGRRHG--------- 150
R G + GER G++ +R H + G+ G + Q P RHG
Sbjct: 1669 RSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSH 1728
Query: 151 ---GQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGG---CRRGG-GRRCG 203
G G G ++ R G +V G + H +G C +G G G
Sbjct: 1729 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG 1788
Query: 204 HVRVGVREQAS---ERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDT 260
+E +S HGQ G QG S R G G G
Sbjct: 1789 QSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQH 1848
Query: 261 GGGPRNRGQEGTHASGRHAGEGAPH 285
G G G H SG G H
Sbjct: 1849 GSGSGWSSSSGRHGSGSGQSSGFGH 1873
Score = 37.7 bits (86), Expect = 0.025
Identities = 49/205 (23%), Positives = 62/205 (30%), Gaps = 24/205 (11%)
Query: 105 RQGHGAGGERGGAAVEFRARVHCH---------RGRAGGQGGDFAVQGPRGRRHG----- 150
R G + GER G++ +R H GR G G +G G G
Sbjct: 2139 RSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSH 2198
Query: 151 ---GQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGG---CRRGG-GRRCG 203
G G G ++ R G +V G + H +G C +G G G
Sbjct: 2199 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG 2258
Query: 204 HVRVGVREQAS---ERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDT 260
+E +S HGQ G QG S R G G G
Sbjct: 2259 QSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQH 2318
Query: 261 GGGPRNRGQEGTHASGRHAGEGAPH 285
G G G H SG G H
Sbjct: 2319 GSGSGWSSSSGRHGSGSGQSSGFGH 2343
Score = 37.4 bits (85), Expect = 0.033
Identities = 65/283 (22%), Positives = 90/283 (31%), Gaps = 48/283 (16%)
Query: 128 HRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVA 187
H G+ G + Q P HG +G G + RH G G + HG G
Sbjct: 875 HHASGRGRHGSGSGQSPG---HGQRGSGSGQSPSYGRHGSGSGRSSSSGRHG----SGSG 927
Query: 188 VHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRS 247
G + G+ G+ + G S GH + E G R +
Sbjct: 928 QSSGFGHKSSSGQSSGYTQHG-----SGSGHSSSY---------EQHGSRSGQSSRSEQH 973
Query: 248 GRGHGRGIQARDTGGGPRNRGQEGTHAS----------GRH-AGEG-----APHGKLAGV 291
G G G G R G H S GRH +G G P+ +G
Sbjct: 974 GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGW 1033
Query: 292 QEERVPVEELLARQA-RGEAEARQG-ALGQVRGGRVRLHRERREGLLARERARLFHLGRR 349
R P E + G E+R G + G + G H G + G+
Sbjct: 1034 SSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGH-SSTHGQHGSTSGQSSSCGQH 1092
Query: 350 CALANRAPALLRAQAASAGRDGGGAMASGIYQRAGIAIEHKPG 392
A + Q++S G+ G G+ S Y R G PG
Sbjct: 1093 GASS--------GQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG 1127
Score = 37.0 bits (84), Expect = 0.043
Identities = 68/317 (21%), Positives = 98/317 (30%), Gaps = 48/317 (15%)
Query: 107 GHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRR---HG--GQGGGEQTAAV 161
GH + E+ G+ +R H G + G + G R+ HG G G G+ +
Sbjct: 952 GHSSSYEQHGSRSGQSSRSEQH-GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS 1010
Query: 162 RDRHRDGVGAVAQ---------------PRAHGVQIEEGVAVHRAGGCRRGG----GRRC 202
R RH G G + P G G+ + + G G
Sbjct: 1011 RGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSS 1070
Query: 203 GHVRV-----GVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQA 257
GH Q+S G A GQ G G G + SG G G
Sbjct: 1071 GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 1130
Query: 258 RDTGGGPRNRGQEGTHASG-----RHAGEGAPHGKLAGVQEERVPVEELLARQARGEAEA 312
R G G R G H SG G+ G+ +G + + G
Sbjct: 1131 R--GSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG 1188
Query: 313 RQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQAASAGRDGG 372
GQ + R R G + + H G+ + + Q++ GR G
Sbjct: 1189 HSSGYGQHGSRSGQSSRGERHGSSSGSSS---HYGQHGSGSR--------QSSGHGRQGS 1237
Query: 373 GAMASGIYQRAGIAIEH 389
G+ S R G + H
Sbjct: 1238 GSGHSPSRGRHGSGLGH 1254
Score = 37.0 bits (84), Expect = 0.043
Identities = 64/318 (20%), Positives = 105/318 (33%), Gaps = 62/318 (19%)
Query: 101 AEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHG--------GQ 152
+ +G+QG G+G RGR G G + G G G G
Sbjct: 2287 SSYGQQGSGSGQSPS-------------RGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS 2333
Query: 153 GGGEQT-----------AAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRR 201
G G+ + ++ +H G G + HG + + R G G
Sbjct: 2334 GSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSS-GSSSS 2392
Query: 202 CGHVRVGVREQASERGHGQALG--------------GQDVLLEVEGQGGRGRPGQSLRRS 247
G G R+ HG G GQ G G + S
Sbjct: 2393 YGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYES 2452
Query: 248 GRGHGRGIQARDTGGGPRN-RGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLARQA 306
G GH G+ R++ G + GQ G +S H+ HG +G + +
Sbjct: 2453 GSGHSSGLGHRESRSGQSSGYGQHG--SSSGHSSTHGQHGSTSG---------QSSSCGQ 2501
Query: 307 RGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQAAS 366
G + + + GQ G + R+G + + G+R + + ++P+ R + S
Sbjct: 2502 HGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP---GHGQRGSGSRQSPSYGRHGSGS 2558
Query: 367 AGRDGGGAMASGIYQRAG 384
G SG+ + +G
Sbjct: 2559 GRSSSSGQHGSGLGESSG 2576
Score = 36.2 bits (82), Expect = 0.073
Identities = 68/320 (21%), Positives = 106/320 (33%), Gaps = 64/320 (20%)
Query: 101 AEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAA 160
+ +G+QG G+G RGR G G +G G G ++
Sbjct: 1817 SSYGQQGSGSGQSPS-------------RGRHGSGSG-------HSSSYGQHGSGSGWSS 1856
Query: 161 VRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGG--RRCGHVRVGVREQASERG- 217
RH G G ++ G E + +G + G G + + G R S RG
Sbjct: 1857 SSGRHGSGSG-----QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE 1911
Query: 218 -HGQALGG------------QDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGP 264
HG + G Q + G G P S R G G G+ G G
Sbjct: 1912 QHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGS 1971
Query: 265 RNRGQEGTHASGRHAGEGAPH-----GKLAGVQEERVPVEELLARQARGEAEARQGALGQ 319
G + SG G H G+ +G + G A + + GQ
Sbjct: 1972 GWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQ 2031
Query: 320 --VRGGRVRLHRERREGLLARERARLFHLGRRCALANRAPALLR-----AQAASAGRDGG 372
G+ H + G ++ GR+ + + ++P + Q+ S GR G
Sbjct: 2032 HGASSGQSSSHGQHGSG-----SSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 2086
Query: 373 GAMASGIYQRAGIAIEHKPG 392
G+ R+ + +H PG
Sbjct: 2087 GS------GRSSSSGQHGPG 2100
Score = 34.7 bits (78), Expect = 0.21
Identities = 61/295 (20%), Positives = 81/295 (27%), Gaps = 47/295 (15%)
Query: 107 GHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHG------------GQGG 154
GHG G G + RGR G G + P G G G
Sbjct: 2405 GHGQHGSGSGQSPS------PSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSS 2458
Query: 155 GEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQAS 214
G R G G H + H G G CG + +S
Sbjct: 2459 GLGHRESRSGQSSGYGQHGSSSGHS-------STHGQHGSTSGQSSSCGQHGASSGQSSS 2511
Query: 215 ERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHA 274
HG Q +G G PG R SG +G G G H
Sbjct: 2512 HGQHGSG-SSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG--RSSSSGQHG 2568
Query: 275 SGRHAGEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREG 334
SG G H + + Q + G GQ + R R G
Sbjct: 2569 SGLGESSGFGHHESSSGQSS--------SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 2620
Query: 335 LLARERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMASGIYQRAGIAIEH 389
+ + H G+ + + Q++ GR G G+ S R G + H
Sbjct: 2621 SSSGSSS---HYGQHGSGSR--------QSSGHGRQGSGSGQSPSRGRHGSGLGH 2664
Score = 34.3 bits (77), Expect = 0.28
Identities = 60/292 (20%), Positives = 79/292 (27%), Gaps = 38/292 (13%)
Query: 107 GHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHG------------GQGG 154
GHG G G + RGR G G + GP G G G
Sbjct: 1935 GHGQHGSGSGQSPS------PSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSS 1988
Query: 155 GEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQAS 214
G R G G H + H G G CG + +S
Sbjct: 1989 GLGHRESRSGQSSGYGQHGSSSGHS-------STHGQHGSASGQSSSCGQHGASSGQSSS 2041
Query: 215 ERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHA 274
HG Q +G G PG R SG +G G G H
Sbjct: 2042 HGQHGSG-SSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG--RSSSSGQHG 2098
Query: 275 SGRHAGEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREG 334
G G H + + Q + G GQ + R R G
Sbjct: 2099 PGLGESSGFGHHESSSGQSS--------SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 2150
Query: 335 LLARERARL--FHLGRRCALANRAPALLRAQAASAGRDGGGAMASGIYQRAG 384
+ +R G R + + + S GR G G+ S + + G
Sbjct: 2151 SSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHG 2202
Score = 33.5 bits (75), Expect = 0.47
Identities = 48/228 (21%), Positives = 69/228 (30%), Gaps = 15/228 (6%)
Query: 64 SGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFR- 122
SG G G +G G + + + + R G HG+G + + R
Sbjct: 489 SGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRH 548
Query: 123 ---ARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGG-GEQTAAVRDRHRDGVGAVAQPRAH 178
+R G G G + +GP G G G Q + R G G H
Sbjct: 549 ESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQES--RSGQSSGYGQHGSSSGH 606
Query: 179 GVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRG 238
+ H G G CG + +S HG Q +G G
Sbjct: 607 S-------STHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSG-SSQSSRYGQQGSGSGQ 658
Query: 239 RPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHG 286
P + S GH +G G + SG+ +G G G
Sbjct: 659 SPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSG 706
Score = 32.7 bits (73), Expect = 0.80
Identities = 46/197 (23%), Positives = 67/197 (34%), Gaps = 39/197 (19%)
Query: 103 FGRQGHGAG---GERGGAAVEFRARVHCHRGRAGGQGGDFAVQGP------RGRRHGGQG 153
FG+ G+G + G A+ F ++ GR G G + G + +G
Sbjct: 817 FGQHESGSGQGYSQHGSASGHFSSQ-----GRHGSTSGQSSSSGQHDSSSGQSSSYGQHE 871
Query: 154 GGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQA 213
A+ R RH G G Q HG + G G G G +
Sbjct: 872 SASHHASGRGRHGSGSG---QSPGHGQR-----------GSGSGQSPSYGRHGSGSGRSS 917
Query: 214 SERGHGQALGGQDVLLEVEGQGGRGRPGQS----LRRSGRGHGRGIQARDTGGGPRNRGQ 269
S HG G + G G + GQS SG GH + + G +R +
Sbjct: 918 SSGRHGSGSG------QSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSE 971
Query: 270 EGTHASGRHAGEGAPHG 286
+ +SG + G HG
Sbjct: 972 QHGSSSGSSSSYG-QHG 987
Score = 32.7 bits (73), Expect = 0.80
Identities = 43/192 (22%), Positives = 67/192 (34%), Gaps = 39/192 (20%)
Query: 103 FGRQGHGAG-----GERGGAAVEFRARVHCHRGRAGGQGGDFAVQGP---RGRRHGGQGG 154
+ + G G+G G+ G + + + G + GQ G + +G QG
Sbjct: 1767 YSQHGSGSGHFCSQGQHGSTSGQ--SSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGS 1824
Query: 155 GEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQAS 214
G + R RH G G + HG G + G R G G Q+S
Sbjct: 1825 GSGQSPSRGRHGSGSGHSSSYGQHG----SGSGWSSSSG-RHGSGSG----------QSS 1869
Query: 215 ERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHA 274
GH ++ Q G + SG GH + + G +RG++ +
Sbjct: 1870 GFGHHESSSWQS-------------SGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSS 1916
Query: 275 SGRHAGEGAPHG 286
SG + G HG
Sbjct: 1917 SGSSSSYG-QHG 1927
Score = 32.3 bits (72), Expect = 1.1
Identities = 53/224 (23%), Positives = 66/224 (29%), Gaps = 47/224 (20%)
Query: 108 HGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRR---HGGQGGGEQTAAVRDR 164
H +G + G+ +R H G + G + G + HG QG G + R R
Sbjct: 722 HSSGYRKHGSRSGQSSRSEQH-GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVR 780
Query: 165 HRDGVGAVAQPRAHGV---------QIEEGVAVHRAGGCRRGG--------GRRCGHVRV 207
H G + HG E G G G G GH
Sbjct: 781 HGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSS 840
Query: 208 GVRE-----QASERGHGQALGGQDVLLEVEGQ--------GGRGR--------PGQSLRR 246
R Q+S G + GQ GQ GRGR PG R
Sbjct: 841 QGRHGSTSGQSSSSGQHDSSSGQS---SSYGQHESASHHASGRGRHGSGSGQSPGHGQRG 897
Query: 247 SGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAG 290
SG G +G G G H SG G H +G
Sbjct: 898 SGSGQSPSYGRHGSGSG--RSSSSGRHGSGSGQSSGFGHKSSSG 939
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 51.6 bits (122), Expect = 2e-06
Identities = 52/206 (25%), Positives = 69/206 (33%), Gaps = 25/206 (12%)
Query: 104 GRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRD 163
G GHG +RG RA H + G G G GE ++V +
Sbjct: 2008 GHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHE 2067
Query: 164 RHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGH-------VRVGVREQASER 216
RH G H G G R G R GH V GV S
Sbjct: 2068 RHGTTHGQTGDTTRHA---HSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGH 2124
Query: 217 GHGQALGGQ-DVLLEVEGQGG--RGRPGQSLRRSGRGHGRGIQARD-TGGGPRNRGQEG- 271
+GQA + + G+ G G+ G + R GHG+ Q T G R+ E
Sbjct: 2125 TYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESS 2184
Query: 272 ----------THASGRHAGEGAPHGK 287
TH+ H+ G+ HG+
Sbjct: 2185 DSEVHSEASPTHSGHTHSQAGSRHGQ 2210
Score = 47.0 bits (110), Expect = 4e-05
Identities = 53/203 (26%), Positives = 65/203 (32%), Gaps = 31/203 (15%)
Query: 102 EFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGG--EQTA 159
E G HG + G R H + G G G HG G E +
Sbjct: 1931 EHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHS--GHTHGQAGSHYPESGS 1988
Query: 160 AVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRV-------GVREQ 212
+V +RH G A HG G G R G R GH GV
Sbjct: 1989 SVHERHGTTHGQTADTTRHG---HSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHT 2045
Query: 213 ASERGHGQALGGQDVLLEVEGQGG----------RGRPGQSLRRSGRGHGRGIQARDTGG 262
S HGQA G Q G+ G G+ G + R + GHG+ Q
Sbjct: 2046 HSGHAHGQA-GSQ------HGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTA 2098
Query: 263 GPRNRGQEGTHASGRHAGEGAPH 285
G R G + S H+G H
Sbjct: 2099 GRRGSGHSESSDSEVHSGVSHTH 2121
Score = 45.4 bits (106), Expect = 1e-04
Identities = 50/198 (25%), Positives = 64/198 (32%), Gaps = 20/198 (10%)
Query: 107 GHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGG--GEQTAAVRDR 164
GHG + G R+ H + G G RG HG G GE + V +R
Sbjct: 1784 GHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGESESIVDER 1843
Query: 165 HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGH-------VRVGVREQASERG 217
H G H + G G G RR GH V G S
Sbjct: 1844 HGTTHGQTGDTSGHS---QSGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHT 1900
Query: 218 HGQAL---GGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRG-QEGTH 273
H QA G + + Q G+ G + HG+ IQ G R G E +
Sbjct: 1901 HSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSD 1960
Query: 274 ASG----RHAGEGAPHGK 287
+ G H G HG+
Sbjct: 1961 SEGPSGVSHTHSGHTHGQ 1978
Score = 42.0 bits (97), Expect = 0.001
Identities = 47/195 (24%), Positives = 63/195 (32%), Gaps = 12/195 (6%)
Query: 104 GRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGG--GEQTAAV 161
G GHG +RG R H + G + + HG G GE + V
Sbjct: 1402 GHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTV 1461
Query: 162 RDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGC--RRGGGR---RCGHVRVGVREQASER 216
RH G H G + R RRG G V G S
Sbjct: 1462 HGRHGTTHGQTGDTTRH-AHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGH 1520
Query: 217 GHGQA---LGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARD-TGGGPRNRGQEGT 272
HGQ+ G + ++ + G+ G + R S GH + Q T G R E T
Sbjct: 1521 THGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSEST 1580
Query: 273 HASGRHAGEGAPHGK 287
+ G PH +
Sbjct: 1581 DSEVHSGGSHRPHSR 1595
Score = 42.0 bits (97), Expect = 0.001
Identities = 57/241 (23%), Positives = 77/241 (31%), Gaps = 52/241 (21%)
Query: 102 EFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHG----------- 150
E G HG G G + H H G++ +G + G RG H
Sbjct: 1456 ESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGS--STTGRRGSGHSESSDSEVHSGG 1513
Query: 151 ---------GQGG---GEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGG 198
GQ G GE + + DRHR G H E G R G
Sbjct: 1514 SHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTT---QTGSRTTG 1570
Query: 199 GRRCGH-------VRVGVREQASERGHGQALGG---QDVLLEVEGQGG--RGRPGQSLRR 246
+R H V G + R H G ++ V + G G+ G +
Sbjct: 1571 RQRTSHSESTDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGH 1630
Query: 247 SGRGHGRGIQ--ARDTG----------GGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEE 294
S GHG+ Q +R TG + G TH H G+ HG+ + E
Sbjct: 1631 SHSGHGQSTQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESIVPE 1690
Query: 295 R 295
R
Sbjct: 1691 R 1691
Score = 40.0 bits (92), Expect = 0.005
Identities = 42/197 (21%), Positives = 60/197 (30%), Gaps = 20/197 (10%)
Query: 108 HGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRD 167
HG + G R H + G G GE + V +RH
Sbjct: 1710 HGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGT 1769
Query: 168 GVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRV-------GVREQASERGH-- 218
G H G G R G R GH G ++ RGH
Sbjct: 1770 IHGQTGDTTRHA---HSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTH 1826
Query: 219 ---GQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGT--- 272
G G + +++ G+ G + S GHG+ Q+ + G R G +
Sbjct: 1827 GQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDS 1886
Query: 273 --HASGRHAGEGAPHGK 287
H+ G H G H +
Sbjct: 1887 EVHSGGSHTHSGHTHSQ 1903
Score = 38.1 bits (87), Expect = 0.019
Identities = 81/418 (19%), Positives = 141/418 (33%), Gaps = 85/418 (20%)
Query: 103 FGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVR 162
FG+ G G+G G E R+R + GQ G + Q +HG G QT+
Sbjct: 1051 FGQHGTGSGQSSGFGQYESRSRQSSY-----GQHGSGSSQSSGYGQHGSNSG--QTS--- 1100
Query: 163 DRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQAL 222
G HR G + G G G + + HG
Sbjct: 1101 ----------------------GFGQHRPGSGQSSG---FGQYGSGSGQSSGFGQHGSGT 1135
Query: 223 GGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRN------RGQEGTHASG 276
G + E + G+ GQ +G G ++G GP G + +SG
Sbjct: 1136 GKSSGFAQHEYRSGQSSYGQ--HGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSG 1193
Query: 277 RH---AGEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGR--------- 324
+H +G+ G+ + + G+ E++Q G GR
Sbjct: 1194 QHISDSGQSTGFGQYGSGSGQSTGL---------GQGESQQVESGSTVHGRQETTHGQTI 1244
Query: 325 -VRLHRERREGLLARERARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMASGIYQRA 383
H + +G + +R+ RR + + + + + ++ + + A Y ++
Sbjct: 1245 NTTRHSQSGQGQSTQTGSRVTR-RRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKS 1303
Query: 384 GIAIEHKPGCL----CSTEKFCLFGREPRMQTKCKT-------HADAQFFSLQVHLGVVL 432
G + + G T + G QT +T H+DA +VH GV
Sbjct: 1304 GSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFSHSDAT--DSEVHSGV-- 1359
Query: 433 HLFFGLHGLQRPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERRRAVGRQRQRG 490
H ++ + G Q GE ++ + H+ + + G+ G+ QRG
Sbjct: 1360 --SHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGH--GQSTQRG 1413
Score = 37.7 bits (86), Expect = 0.025
Identities = 50/213 (23%), Positives = 65/213 (30%), Gaps = 25/213 (11%)
Query: 105 RQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDR 164
+ GHG + G + R H + G GE + V R
Sbjct: 1859 QSGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKR 1918
Query: 165 HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRV-------GVREQASERG 217
H+ G HG G + G R G R GH GV S
Sbjct: 1919 HQTTHGQTGDTTEHG-HPSHGQTIQT--GSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHT 1975
Query: 218 HGQALGGQ-DVLLEVEGQGG--RGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQ----- 269
HGQA + V + G G+ + R GHG+ Q G R G
Sbjct: 1976 HGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSD 2035
Query: 270 -EG------THASGRHAGEGAPHGKLAGVQEER 295
EG TH+ H G+ HG+ ER
Sbjct: 2036 SEGHSGVSHTHSGHAHGQAGSQHGESGSSVHER 2068
Score = 36.6 bits (83), Expect = 0.056
Identities = 43/193 (22%), Positives = 58/193 (30%), Gaps = 39/193 (20%)
Query: 106 QGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRH 165
Q GE G A +H +G GQ GD G G Q G T R H
Sbjct: 2128 QARSQHGESGSA-------IHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSH 2180
Query: 166 RDG----VGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQA 221
+ V + A P G + + H G G + H + G + + G+
Sbjct: 2181 SESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGY--- 2237
Query: 222 LGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGE 281
GQS +R R GR G G H+ G H
Sbjct: 2238 -------------------GQSTQRGSRTTGR------RGSGHSESSDSEVHSWGSHTHS 2272
Query: 282 GAPHGKLAGVQEE 294
G G+ Q +
Sbjct: 2273 GHIQGQAGSQQRQ 2285
Score = 35.0 bits (79), Expect = 0.16
Identities = 54/247 (21%), Positives = 78/247 (31%), Gaps = 39/247 (15%)
Query: 101 AEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAA 160
A FG+ G G+G G E R+ + GQ G + Q +HG G QT+
Sbjct: 818 AGFGQHGSGSGQSSGFGQHESRSHQSSY-----GQHGSGSSQSSGYGQHGSSSG--QTSG 870
Query: 161 VRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG--- 217
+HR G + HG + + G G G+ G + R S G
Sbjct: 871 F-GQHRSSSGQYSGFGQHGSGSGQSSGFGQHG---TGSGQYSGFGQHESRSHQSSYGQHG 926
Query: 218 -----------HGQALG------------GQDVLLEVEGQGGRGRPGQSLRRSGRGHGRG 254
HG + G GQ G G G SG G G
Sbjct: 927 SGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSG 986
Query: 255 IQARDTGGGPRNRGQEGTHA--SGRHAGEGAPHGKLAGVQEERVPVEELLARQARGEAEA 312
++ N GQ G+ + S + G+ G+ G + R + G
Sbjct: 987 FGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSD 1046
Query: 313 RQGALGQ 319
+ GQ
Sbjct: 1047 QSSGFGQ 1053
Score = 33.9 bits (76), Expect = 0.36
Identities = 48/197 (24%), Positives = 58/197 (29%), Gaps = 17/197 (8%)
Query: 108 HGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRD 167
HG + G E + VH G GQ GD G Q G T H +
Sbjct: 1749 HGQARSQHG---ESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSE 1805
Query: 168 -----GVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCG--HVRVGVREQASERGHGQ 220
G +Q R H G A + G R G H + G S+ GHGQ
Sbjct: 1806 YSDSEGHSGFSQ-RPHSRGHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQ 1864
Query: 221 ALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAG 280
+ GR R G S H G + R Q G S H
Sbjct: 1865 STQSGS------STTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKR 1918
Query: 281 EGAPHGKLAGVQEERVP 297
HG+ E P
Sbjct: 1919 HQTTHGQTGDTTEHGHP 1935
Score = 33.1 bits (74), Expect = 0.62
Identities = 46/234 (19%), Positives = 75/234 (32%), Gaps = 13/234 (5%)
Query: 103 FGRQGHGAGGERGGAAVEFRARVHCH--RGRAGGQGGDFAVQGPR---GRRHGGQGGGEQ 157
FG+ G +G G E R+R + G Q + G R G G G G+
Sbjct: 518 FGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQS 577
Query: 158 TAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRA-------GGCRRGGGRRCGHVRVGVR 210
T + G + G G H + G G + G+ + G R
Sbjct: 578 TGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSR 637
Query: 211 EQASERGHGQALGGQDVLLEV-EGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQ 269
+ + HG + G G GQ + SG+ G G +G +
Sbjct: 638 QTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHG 697
Query: 270 EGTHASGRHAGEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGG 323
G+ S + G+ G+ +G + + + + G + GQ G
Sbjct: 698 FGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSG 751
Score = 32.7 bits (73), Expect = 0.80
Identities = 47/202 (23%), Positives = 65/202 (32%), Gaps = 25/202 (12%)
Query: 103 FGRQGHGAGGERGGAAVEFRARVHCHRGRAGG--QGGDFAVQGPRGRRHGGQ-GGGEQTA 159
FG+ G G+G G E R+ + + G Q + G R GQ G G +
Sbjct: 593 FGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQS 652
Query: 160 AVRDRHRDGVGAVAQPRAH--GVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG 217
++ G G + H G G H + R G G G + +
Sbjct: 653 TGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHES----RSGHSSYGQHGFGSSQSSGYGQ 708
Query: 218 HGQALG------------GQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPR 265
HG + G GQ G G G SG G G ++ G
Sbjct: 709 HGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQS 768
Query: 266 NRGQEGTHASGRHAGEG-APHG 286
+ GQ H+SG G HG
Sbjct: 769 SYGQ---HSSGSSQSSGYGQHG 787
Score = 32.0 bits (71), Expect = 1.4
Identities = 44/192 (22%), Positives = 64/192 (33%), Gaps = 24/192 (12%)
Query: 108 HGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHG-------GQGGGEQTAA 160
H G+ G + + +RV R + + D V RH G + +
Sbjct: 1249 HSQSGQ--GQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGST 1306
Query: 161 VRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGH-------VRVGV--RE 211
VR R G HG G G R G +R H V GV R
Sbjct: 1307 VRRRQGTTHGQRGDTTRHG---HSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRP 1363
Query: 212 QASERGHGQA---LGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRG 268
+ E+ H QA G + + + G+ G++ GHG+ Q G R G
Sbjct: 1364 HSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGRRGSG 1423
Query: 269 QEGTHASGRHAG 280
+ S H+G
Sbjct: 1424 HSESSDSEVHSG 1435
Score = 30.4 bits (67), Expect = 4.0
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 21/200 (10%)
Query: 103 FGRQGHGAGGERG-GAAVEFRARVHC---HRGRAG----GQGGDFAVQGPRGRRHGGQGG 154
FG+ G G+G G G V + H R+G GQ G + Q +HG G
Sbjct: 655 FGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSG 714
Query: 155 GEQTAAVRDRHRDGVGAVAQPRAHGVQIEE--GVAVHRAGGCRRGG----GRRCGHVRVG 208
QT+ +H G + HG + G H +G + G R G G
Sbjct: 715 --QTSGF-GQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYG 771
Query: 209 VREQASER--GHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRN 266
S + G+GQ Q G G G SG G G +G G +
Sbjct: 772 QHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSS 831
Query: 267 RGQEGTHASGRHAGEGAPHG 286
G H S H HG
Sbjct: 832 GF--GQHESRSHQSSYGQHG 849
Score = 29.3 bits (64), Expect = 8.9
Identities = 44/184 (23%), Positives = 57/184 (30%), Gaps = 25/184 (13%)
Query: 107 GHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHR 166
G+G G G F HR +G G G G G ++ +H
Sbjct: 1011 GYGQHGSSSGQTTGFGQ----HRSSSGQYSG-----------FGQHGSGSDQSSGFGQHG 1055
Query: 167 DGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVRE-QASERGHGQALGGQ 225
G G Q G Q E G G + G+ + G Q S G + GQ
Sbjct: 1056 TGSG---QSSGFG-QYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQ 1111
Query: 226 DVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHAS-----GRHAG 280
G G G SG G G + G + GQ GT +S G+H
Sbjct: 1112 SSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHES 1171
Query: 281 EGAP 284
P
Sbjct: 1172 GSGP 1175
>gi|239750846 PREDICTED: hypothetical protein [Homo sapiens]
Length = 463
Score = 50.1 bits (118), Expect = 5e-06
Identities = 82/269 (30%), Positives = 99/269 (36%), Gaps = 63/269 (23%)
Query: 150 GGQGGGEQ-------TAAVRDRHRDGVGAVAQPRAHGVQ--------IEEGVAVHRAGGC 194
G GGG Q + V R R GVG+ H VQ G AGGC
Sbjct: 4 GEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGC 63
Query: 195 RRGGGRRCGHVRVGVREQAS-------ERGHGQALGGQDVLLEVEGQGGR---GRPGQSL 244
RG G G VREQ +RGHG G L G GG+ R Q L
Sbjct: 64 LRGRGAERGR---RVREQGGDGRWQRRQRGHGGRRG-----LNGHGDGGQRLARRVAQRL 115
Query: 245 RRSGRG------HGRGIQARDTGGGP-------RNRGQEGTHASGR--------HAGEGA 283
+R G HG G D GG R G+ G H GEG
Sbjct: 116 QRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQ 175
Query: 284 PHGKLAGVQEERVPVEELLARQARGEAEARQ-----GALGQVRGGRVRLHRERREGLLAR 338
P L +++ + E +L +ARG A Q G L QVR R R E + GLL +
Sbjct: 176 PPRHLVFPRDDVLDGEGVL--EARGLRHAAQVVGGGGHLWQVR-ARGRQRAEPQLGLLLQ 232
Query: 339 ERARLFHL-GRRCALANRAPALLRAQAAS 366
R+ L GR+ AL Q A+
Sbjct: 233 VLRRVGWLAGRQVVGLKHLEALAAPQEAA 261
Score = 37.4 bits (85), Expect = 0.033
Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 30/154 (19%)
Query: 106 QGHGAGGER----GGAAVE---FRARVHCHRGRAGGQGGDFAVQ-------GPRGRRHGG 151
QG G GER GGAA+ R R R QGGD Q G RG G
Sbjct: 42 QGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHG 101
Query: 152 QGGGEQTAAVRDR-HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVR 210
GG V R R VGAV R HG + G V AGG HV
Sbjct: 102 DGGQRLARRVAQRLQRHAVGAVVATR-HG---DGGGRVDHAGGAI--------HVWPAGA 149
Query: 211 EQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 244
++A+ HG L G+ V GG G+P + L
Sbjct: 150 QRAA---HGSQLVGERVGSGHRLHGGEGQPPRHL 180
Score = 34.7 bits (78), Expect = 0.21
Identities = 40/132 (30%), Positives = 50/132 (37%), Gaps = 26/132 (19%)
Query: 104 GRQGHGAGGERGGAAVEFRARVHC-------HRGRAGGQ----GGDFAV--QGPRGRRHG 150
G GHG GG+R V R + H G GG+ GG V G + HG
Sbjct: 96 GLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHG 155
Query: 151 GQGGGEQTAAVRDRHRDGVGAVAQPRAHGV----QIEEGVAVHRAGGCRR-----GGGRR 201
Q GE+ + H G QP H V + +G V A G R GGG
Sbjct: 156 SQLVGERVGSGHRLH----GGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGH 211
Query: 202 CGHVRVGVREQA 213
VR R++A
Sbjct: 212 LWQVRARGRQRA 223
>gi|239745208 PREDICTED: hypothetical protein XP_002343389 [Homo
sapiens]
Length = 463
Score = 50.1 bits (118), Expect = 5e-06
Identities = 82/269 (30%), Positives = 99/269 (36%), Gaps = 63/269 (23%)
Query: 150 GGQGGGEQ-------TAAVRDRHRDGVGAVAQPRAHGVQ--------IEEGVAVHRAGGC 194
G GGG Q + V R R GVG+ H VQ G AGGC
Sbjct: 4 GEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGC 63
Query: 195 RRGGGRRCGHVRVGVREQAS-------ERGHGQALGGQDVLLEVEGQGGR---GRPGQSL 244
RG G G VREQ +RGHG G L G GG+ R Q L
Sbjct: 64 LRGRGAERGR---RVREQGGDGRWQRRQRGHGGRRG-----LNGHGDGGQRLARRVAQRL 115
Query: 245 RRSGRG------HGRGIQARDTGGGP-------RNRGQEGTHASGR--------HAGEGA 283
+R G HG G D GG R G+ G H GEG
Sbjct: 116 QRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQ 175
Query: 284 PHGKLAGVQEERVPVEELLARQARGEAEARQ-----GALGQVRGGRVRLHRERREGLLAR 338
P L +++ + E +L +ARG A Q G L QVR R R E + GLL +
Sbjct: 176 PPRHLVFPRDDVLDGEGVL--EARGLRHAAQVVGGGGHLWQVR-ARGRQRAEPQLGLLLQ 232
Query: 339 ERARLFHL-GRRCALANRAPALLRAQAAS 366
R+ L GR+ AL Q A+
Sbjct: 233 VLRRVGWLAGRQVVGLKHLEALAAPQEAA 261
Score = 37.4 bits (85), Expect = 0.033
Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 30/154 (19%)
Query: 106 QGHGAGGER----GGAAVE---FRARVHCHRGRAGGQGGDFAVQ-------GPRGRRHGG 151
QG G GER GGAA+ R R R QGGD Q G RG G
Sbjct: 42 QGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHG 101
Query: 152 QGGGEQTAAVRDR-HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVR 210
GG V R R VGAV R HG + G V AGG HV
Sbjct: 102 DGGQRLARRVAQRLQRHAVGAVVATR-HG---DGGGRVDHAGGAI--------HVWPAGA 149
Query: 211 EQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 244
++A+ HG L G+ V GG G+P + L
Sbjct: 150 QRAA---HGSQLVGERVGSGHRLHGGEGQPPRHL 180
Score = 34.7 bits (78), Expect = 0.21
Identities = 40/132 (30%), Positives = 50/132 (37%), Gaps = 26/132 (19%)
Query: 104 GRQGHGAGGERGGAAVEFRARVHC-------HRGRAGGQ----GGDFAV--QGPRGRRHG 150
G GHG GG+R V R + H G GG+ GG V G + HG
Sbjct: 96 GLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHG 155
Query: 151 GQGGGEQTAAVRDRHRDGVGAVAQPRAHGV----QIEEGVAVHRAGGCRR-----GGGRR 201
Q GE+ + H G QP H V + +G V A G R GGG
Sbjct: 156 SQLVGERVGSGHRLH----GGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGH 211
Query: 202 CGHVRVGVREQA 213
VR R++A
Sbjct: 212 LWQVRARGRQRA 223
>gi|239756319 PREDICTED: hypothetical protein [Homo sapiens]
Length = 463
Score = 49.7 bits (117), Expect = 6e-06
Identities = 78/257 (30%), Positives = 96/257 (37%), Gaps = 56/257 (21%)
Query: 155 GEQTAAVRDRHRDGVGAVAQPRAHGVQ--------IEEGVAVHRAGGCRRGGGRRCGHVR 206
G+ + V R R GVG+ H VQ G AGGC RG G G
Sbjct: 16 GKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGR-- 73
Query: 207 VGVREQAS-------ERGHGQALGGQDVLLEVEGQGGR---GRPGQSLRRSGRG------ 250
VREQ +RGHG G L G GG+ R Q L+R G
Sbjct: 74 -RVREQGGDGRWQRRQRGHGGRRG-----LNGHGDGGQRLARRVAQRLQRHAVGAVVATR 127
Query: 251 HGRGIQARDTGGGP-------RNRGQEGTHASGR--------HAGEGAPHGKLAGVQEER 295
HG G D GG R G+ G H GEG P L +++
Sbjct: 128 HGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDV 187
Query: 296 VPVEELLARQARGEAEARQ-----GALGQVRGGRVRLHRERREGLLARERARLFHL-GRR 349
+ E +L +ARG A Q G L QVR R R E + GLL + R+ L GR+
Sbjct: 188 LDGEGVL--EARGLRHAAQVVGGGGHLWQVR-ARGRQRAEPQLGLLLQVLRRVGWLAGRQ 244
Query: 350 CALANRAPALLRAQAAS 366
AL Q A+
Sbjct: 245 VVGLKHLEALAAPQEAA 261
Score = 37.4 bits (85), Expect = 0.033
Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 30/154 (19%)
Query: 106 QGHGAGGER----GGAAVE---FRARVHCHRGRAGGQGGDFAVQ-------GPRGRRHGG 151
QG G GER GGAA+ R R R QGGD Q G RG G
Sbjct: 42 QGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHG 101
Query: 152 QGGGEQTAAVRDR-HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVR 210
GG V R R VGAV R HG + G V AGG HV
Sbjct: 102 DGGQRLARRVAQRLQRHAVGAVVATR-HG---DGGGRVDHAGGAI--------HVWPAGA 149
Query: 211 EQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 244
++A+ HG L G+ V GG G+P + L
Sbjct: 150 QRAA---HGSQLVGERVGSGHRLHGGEGQPPRHL 180
Score = 37.0 bits (84), Expect = 0.043
Identities = 47/144 (32%), Positives = 53/144 (36%), Gaps = 23/144 (15%)
Query: 183 EEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQ 242
E G A G RGG CG V R G G+ G GG G
Sbjct: 14 EPGKASEVVGRRTRGGVGSCGSVH-------RHRVQGGGRAGE----RFAGGGGAALAGG 62
Query: 243 SLRRSGRGHGRGIQARDTGGGPR-NRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEEL 301
LR GRG RG + R+ GG R R Q G H G +G G Q V +
Sbjct: 63 CLR--GRGAERGRRVREQGGDGRWQRRQRG------HGGRRGLNGHGDGGQRLARRVAQR 114
Query: 302 LARQARGEAEARQGALGQVRGGRV 325
L R A G A + G GGRV
Sbjct: 115 LQRHAVGAVVATRHGDG---GGRV 135
Score = 34.7 bits (78), Expect = 0.21
Identities = 40/132 (30%), Positives = 50/132 (37%), Gaps = 26/132 (19%)
Query: 104 GRQGHGAGGERGGAAVEFRARVHC-------HRGRAGGQ----GGDFAV--QGPRGRRHG 150
G GHG GG+R V R + H G GG+ GG V G + HG
Sbjct: 96 GLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHG 155
Query: 151 GQGGGEQTAAVRDRHRDGVGAVAQPRAHGV----QIEEGVAVHRAGGCRR-----GGGRR 201
Q GE+ + H G QP H V + +G V A G R GGG
Sbjct: 156 SQLVGERVGSGHRLH----GGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGH 211
Query: 202 CGHVRVGVREQA 213
VR R++A
Sbjct: 212 LWQVRARGRQRA 223
>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
sapiens]
Length = 600
Score = 49.3 bits (116), Expect = 8e-06
Identities = 59/197 (29%), Positives = 69/197 (35%), Gaps = 38/197 (19%)
Query: 105 RQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGD---FAVQGPRGRRHGGQGGGEQTAAV 161
R G G G GG GR GG+GGD F +GPRG R GGG
Sbjct: 415 RGGPGGPGGPGGPM-----------GRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRA 463
Query: 162 RDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRR-----GGGRRCGHVRVGVREQASER 216
D G Q A + + A G GG R G
Sbjct: 464 GDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG------------- 510
Query: 217 GHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRN-----RGQEG 271
G G GG+ L++ G GG R G+ R G GRG+ GGG R G
Sbjct: 511 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLM 570
Query: 272 THASGRHAGEGAPHGKL 288
GR G G P GK+
Sbjct: 571 EQMGGRRGGRGGP-GKM 586
>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
sapiens]
Length = 655
Score = 49.3 bits (116), Expect = 8e-06
Identities = 59/197 (29%), Positives = 69/197 (35%), Gaps = 38/197 (19%)
Query: 105 RQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGD---FAVQGPRGRRHGGQGGGEQTAAV 161
R G G G GG GR GG+GGD F +GPRG R GGG
Sbjct: 470 RGGPGGPGGPGGPM-----------GRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRA 518
Query: 162 RDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRR-----GGGRRCGHVRVGVREQASER 216
D G Q A + + A G GG R G
Sbjct: 519 GDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG------------- 565
Query: 217 GHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRN-----RGQEG 271
G G GG+ L++ G GG R G+ R G GRG+ GGG R G
Sbjct: 566 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLM 625
Query: 272 THASGRHAGEGAPHGKL 288
GR G G P GK+
Sbjct: 626 EQMGGRRGGRGGP-GKM 641
>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
sapiens]
Length = 661
Score = 49.3 bits (116), Expect = 8e-06
Identities = 59/197 (29%), Positives = 69/197 (35%), Gaps = 38/197 (19%)
Query: 105 RQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGD---FAVQGPRGRRHGGQGGGEQTAAV 161
R G G G GG GR GG+GGD F +GPRG R GGG
Sbjct: 476 RGGPGGPGGPGGPM-----------GRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRA 524
Query: 162 RDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRR-----GGGRRCGHVRVGVREQASER 216
D G Q A + + A G GG R G
Sbjct: 525 GDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG------------- 571
Query: 217 GHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRN-----RGQEG 271
G G GG+ L++ G GG R G+ R G GRG+ GGG R G
Sbjct: 572 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLM 631
Query: 272 THASGRHAGEGAPHGKL 288
GR G G P GK+
Sbjct: 632 EQMGGRRGGRGGP-GKM 647
>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
sapiens]
Length = 656
Score = 49.3 bits (116), Expect = 8e-06
Identities = 59/197 (29%), Positives = 69/197 (35%), Gaps = 38/197 (19%)
Query: 105 RQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGD---FAVQGPRGRRHGGQGGGEQTAAV 161
R G G G GG GR GG+GGD F +GPRG R GGG
Sbjct: 471 RGGPGGPGGPGGPM-----------GRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRA 519
Query: 162 RDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRR-----GGGRRCGHVRVGVREQASER 216
D G Q A + + A G GG R G
Sbjct: 520 GDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG------------- 566
Query: 217 GHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRN-----RGQEG 271
G G GG+ L++ G GG R G+ R G GRG+ GGG R G
Sbjct: 567 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLM 626
Query: 272 THASGRHAGEGAPHGKL 288
GR G G P GK+
Sbjct: 627 EQMGGRRGGRGGP-GKM 642
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 48.9 bits (115), Expect = 1e-05
Identities = 76/229 (33%), Positives = 88/229 (38%), Gaps = 43/229 (18%)
Query: 60 DSDVSGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFG--RQGHGAGGER--G 115
DS SG RGR G R G++ GGR R +G R G G GG+R G
Sbjct: 383 DSRPSGGDFRGRGYGGER-GYRGR----------GGRGGDRGGYGGDRSGGGYGGDRSSG 431
Query: 116 GAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQP 175
G R+ GG GGD + G G R GG GG DR G G
Sbjct: 432 GGYSGDRS--------GGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDR---GGGYGGDR 480
Query: 176 RAHGVQIEEGVAVHRAG-GCRRG--GGRRCGH--VRVGVREQASERGHGQALGGQDVLLE 230
+G G R G G RG GG R G+ R G S G+G GG
Sbjct: 481 GGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGG----- 535
Query: 231 VEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGG-PRNRGQEGTHASGRH 278
G GG G RSG G+G D GGG +RG G GR+
Sbjct: 536 -SGYGGDRSGGYGGDRSGGGYG-----GDRGGGYGGDRGGYGGKMGGRN 578
Score = 48.1 bits (113), Expect = 2e-05
Identities = 67/207 (32%), Positives = 85/207 (41%), Gaps = 34/207 (16%)
Query: 106 QGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAA---VR 162
+G G GGERG +RGR GG+GGD G G R GG GG++++
Sbjct: 392 RGRGYGGERG------------YRGR-GGRGGDRGGYG--GDRSGGGYGGDRSSGGGYSG 436
Query: 163 DRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCR--RGGGR---RCGHVRVGVREQASERG 217
DR G G +G G R GG RGGG R G+ +RG
Sbjct: 437 DRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRG 496
Query: 218 -HGQALGGQDVLLEVEGQGG-RGRPGQSLRRSG----RGHGRGIQARDTGG--GPRNRGQ 269
+G GG + G GG RG G R G RG G G +GG G R+ G
Sbjct: 497 GYGGDRGGYGG--DRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGG 554
Query: 270 EGTHASGRHAGE-GAPHGKLAGVQEER 295
G G + G+ G GK+ G + R
Sbjct: 555 YGGDRGGGYGGDRGGYGGKMGGRNDYR 581
Score = 36.2 bits (82), Expect = 0.073
Identities = 41/156 (26%), Positives = 53/156 (33%), Gaps = 12/156 (7%)
Query: 139 FAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGG 198
FA + P R GG GGG + R R G G + + RR
Sbjct: 314 FATRRPEFMRGGGSGGGRRGRG-GYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNS 372
Query: 199 GRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRG--RPGQSLRRSGRGH----- 251
+C R + G+ GG+ G+GGRG R G RSG G+
Sbjct: 373 CNQCNEPRPEDSRPSGGDFRGRGYGGE---RGYRGRGGRGGDRGGYGGDRSGGGYGGDRS 429
Query: 252 -GRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHG 286
G G +GGG G + R G G G
Sbjct: 430 SGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRG 465
Score = 36.2 bits (82), Expect = 0.073
Identities = 74/284 (26%), Positives = 85/284 (29%), Gaps = 92/284 (32%)
Query: 100 RAEFGRQGHGAGGERGGAA----------------------------VEFRARVHCH--- 128
R EF R G GG RG + F R C+
Sbjct: 318 RPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCN 377
Query: 129 --------------RGRA----------GGQGGDFAVQGPRGRRHGGQGGGEQTAA---V 161
RGR GG+GGD G G R GG GG++++
Sbjct: 378 EPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYG--GDRSGGGYGGDRSSGGGYS 435
Query: 162 RDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQA 221
DR G G +G G R GG GG R G+ G+G
Sbjct: 436 GDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGG--YGGDRGGGY-------GGDRGGYGGD 486
Query: 222 LGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTG--GGPRNRGQEGTHASGRHA 279
GG G GG R G R G G RG D G GG R+RG G G
Sbjct: 487 RGG--------GYGG-DRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG 537
Query: 280 GEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGG 323
G G G R G R G G RGG
Sbjct: 538 YGGDRSGGYGG------------DRSGGGYGGDRGGGYGGDRGG 569
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 48.9 bits (115), Expect = 1e-05
Identities = 76/229 (33%), Positives = 88/229 (38%), Gaps = 43/229 (18%)
Query: 60 DSDVSGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFG--RQGHGAGGER--G 115
DS SG RGR G R G++ GGR R +G R G G GG+R G
Sbjct: 386 DSRPSGGDFRGRGYGGER-GYRGR----------GGRGGDRGGYGGDRSGGGYGGDRSSG 434
Query: 116 GAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQP 175
G R+ GG GGD + G G R GG GG DR G G
Sbjct: 435 GGYSGDRS--------GGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDR---GGGYGGDR 483
Query: 176 RAHGVQIEEGVAVHRAG-GCRRG--GGRRCGH--VRVGVREQASERGHGQALGGQDVLLE 230
+G G R G G RG GG R G+ R G S G+G GG
Sbjct: 484 GGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGG----- 538
Query: 231 VEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGG-PRNRGQEGTHASGRH 278
G GG G RSG G+G D GGG +RG G GR+
Sbjct: 539 -SGYGGDRSGGYGGDRSGGGYG-----GDRGGGYGGDRGGYGGKMGGRN 581
Score = 48.1 bits (113), Expect = 2e-05
Identities = 67/207 (32%), Positives = 85/207 (41%), Gaps = 34/207 (16%)
Query: 106 QGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAA---VR 162
+G G GGERG +RGR GG+GGD G G R GG GG++++
Sbjct: 395 RGRGYGGERG------------YRGR-GGRGGDRGGYG--GDRSGGGYGGDRSSGGGYSG 439
Query: 163 DRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCR--RGGGR---RCGHVRVGVREQASERG 217
DR G G +G G R GG RGGG R G+ +RG
Sbjct: 440 DRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRG 499
Query: 218 -HGQALGGQDVLLEVEGQGG-RGRPGQSLRRSG----RGHGRGIQARDTGG--GPRNRGQ 269
+G GG + G GG RG G R G RG G G +GG G R+ G
Sbjct: 500 GYGGDRGGYGG--DRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGG 557
Query: 270 EGTHASGRHAGE-GAPHGKLAGVQEER 295
G G + G+ G GK+ G + R
Sbjct: 558 YGGDRGGGYGGDRGGYGGKMGGRNDYR 584
Score = 36.2 bits (82), Expect = 0.073
Identities = 41/156 (26%), Positives = 53/156 (33%), Gaps = 12/156 (7%)
Query: 139 FAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGG 198
FA + P R GG GGG + R R G G + + RR
Sbjct: 317 FATRRPEFMRGGGSGGGRRGRG-GYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNS 375
Query: 199 GRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRG--RPGQSLRRSGRGH----- 251
+C R + G+ GG+ G+GGRG R G RSG G+
Sbjct: 376 CNQCNEPRPEDSRPSGGDFRGRGYGGE---RGYRGRGGRGGDRGGYGGDRSGGGYGGDRS 432
Query: 252 -GRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHG 286
G G +GGG G + R G G G
Sbjct: 433 SGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRG 468
Score = 36.2 bits (82), Expect = 0.073
Identities = 74/284 (26%), Positives = 85/284 (29%), Gaps = 92/284 (32%)
Query: 100 RAEFGRQGHGAGGERGGAA----------------------------VEFRARVHCH--- 128
R EF R G GG RG + F R C+
Sbjct: 321 RPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCN 380
Query: 129 --------------RGRA----------GGQGGDFAVQGPRGRRHGGQGGGEQTAA---V 161
RGR GG+GGD G G R GG GG++++
Sbjct: 381 EPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYG--GDRSGGGYGGDRSSGGGYS 438
Query: 162 RDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQA 221
DR G G +G G R GG GG R G+ G+G
Sbjct: 439 GDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGG--YGGDRGGGY-------GGDRGGYGGD 489
Query: 222 LGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTG--GGPRNRGQEGTHASGRHA 279
GG G GG R G R G G RG D G GG R+RG G G
Sbjct: 490 RGG--------GYGG-DRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSG 540
Query: 280 GEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGG 323
G G G R G R G G RGG
Sbjct: 541 YGGDRSGGYGG------------DRSGGGYGGDRGGGYGGDRGG 572
>gi|56699482 hypothetical protein LOC25940 [Homo sapiens]
Length = 518
Score = 48.5 bits (114), Expect = 1e-05
Identities = 55/179 (30%), Positives = 66/179 (36%), Gaps = 17/179 (9%)
Query: 104 GRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRD 163
GR GH GG RGG + H GR GG+G QG G GGG Q RD
Sbjct: 350 GRGGHEQGGGRGGRGG------YDHGGRGGGRGNKH--QGGWTDGGSGGGGGYQDGGYRD 401
Query: 164 RHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALG 223
G + G Q G + G G + G + R Q HG G
Sbjct: 402 SGFQPGGYHGGHSSGGYQ-GGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGH-HGDRGG 459
Query: 224 GQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEG 282
G+ G+GGRG G + G GRG Q GG Q G + H+G G
Sbjct: 460 GRG------GRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGY-QYNHSGFG 511
Score = 43.5 bits (101), Expect = 5e-04
Identities = 60/182 (32%), Positives = 72/182 (39%), Gaps = 28/182 (15%)
Query: 105 RQGHGAGGERGGAAVEFRARVHCHRGRAGG--QGGDFAVQGPRGRRHGGQGGG---EQTA 159
+Q G GG RGG H G GG QGG +G G HGG+GGG +
Sbjct: 331 QQTGGRGGGRGGYE-------HSSYGGRGGHEQGGGRGGRG--GYDHGGRGGGRGNKHQG 381
Query: 160 AVRDRHRDGVGAVAQP--RAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG 217
D G G R G Q H +GG + GG G + +S G
Sbjct: 382 GWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGG-------YGGFQTSSSYTG 434
Query: 218 HGQALGG--QDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHAS 275
G GG QD + G G R G R GRG GRG +A GGG RG + H
Sbjct: 435 SGYQGGGYQQDNRYQDGGHHG-DRGGGRGGRGGRG-GRGGRA-GQGGGWGGRGSQNYHQG 491
Query: 276 GR 277
G+
Sbjct: 492 GQ 493
Score = 32.0 bits (71), Expect = 1.4
Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 9/79 (11%)
Query: 208 GVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNR 267
G ++Q RG G+ GG E GGRG Q R GRG G GGG N+
Sbjct: 328 GPQQQTGGRGGGR--GGY----EHSSYGGRGGHEQGGGRGGRG---GYDHGGRGGGRGNK 378
Query: 268 GQEGTHASGRHAGEGAPHG 286
Q G G G G G
Sbjct: 379 HQGGWTDGGSGGGGGYQDG 397
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 47.8 bits (112), Expect = 2e-05
Identities = 56/219 (25%), Positives = 76/219 (34%), Gaps = 21/219 (9%)
Query: 104 GRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHG----GQGGGEQTA 159
G + G G E G E +G G+ G+ +G G G G+G GE+
Sbjct: 835 GEEEEGEGEEEEGEGEEEEGE---GKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEG 891
Query: 160 AVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHG 219
+G G + + EEG G G G G G E G G
Sbjct: 892 EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEG-EEGEGE--GEEEEGEGEGEDGEGEG 948
Query: 220 QALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEG--THASGR 277
+ G+ E EG+G G+ G G G + G G G+E G
Sbjct: 949 EEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGE--EEEGEGEGEEEEGEEEGEEEGEGE 1006
Query: 278 HAGEGAPHGKLAGVQEERVPVE-ELLARQARGEAEARQG 315
GEG G +EE VE E+ + GE E +G
Sbjct: 1007 EEGEG------EGEEEEEGEVEGEVEGEEGEGEGEEEEG 1039
Score = 35.4 bits (80), Expect = 0.12
Identities = 65/298 (21%), Positives = 94/298 (31%), Gaps = 49/298 (16%)
Query: 67 GLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGG--------ERGGAA 118
G GR G G A D + G + R E R G G +R G
Sbjct: 650 GPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEE 709
Query: 119 VEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAH 178
E + R H+ + + G G+G E+ + ++G G +
Sbjct: 710 QEQKEREQGHQKERNQEMEE------GGEEEHGEGEEEEGDREEEEEKEGEG---KEEGE 760
Query: 179 GVQIE------EGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEV- 231
G ++E EG + G G G E+ RG + GG+ EV
Sbjct: 761 GEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVE 820
Query: 232 -----------EGQG----GRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASG 276
EG+G G G + G G+G + + G G G+EG
Sbjct: 821 EGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEG-EEEGEEGEGEGE 879
Query: 277 RHAGEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREG 334
GEG + G EE + GE E G+ G + E EG
Sbjct: 880 EEEGEGEGEEEGEGEGEE---------EEGEGEGEEEGEGEGEEEEGEGKGEEEGEEG 928
>gi|28875797 small protein rich in arginine and glycine [Homo
sapiens]
Length = 248
Score = 47.4 bits (111), Expect = 3e-05
Identities = 50/132 (37%), Positives = 57/132 (43%), Gaps = 22/132 (16%)
Query: 129 RGRAGGQGGDFAVQG-PRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVA 187
RG GG+G +G PRG GG+ A R R G+ Q G G A
Sbjct: 97 RGAIGGRGLPIIQRGLPRGGLRGGR-------ATRTLLRGGMSLRGQNLLRG-----GRA 144
Query: 188 VHRAGGCRRGGGR-RCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRR 246
V G RRGG R R G R G+ A RG +GG+ G GRGR G R
Sbjct: 145 VAPRMGLRRGGVRGRGGPGRGGLGRGAMGRG---GIGGRG-----RGMIGRGRGGFGGRG 196
Query: 247 SGRGHGRGIQAR 258
GRG GRG AR
Sbjct: 197 RGRGRGRGALAR 208
Score = 39.3 bits (90), Expect = 0.009
Identities = 37/96 (38%), Positives = 40/96 (41%), Gaps = 6/96 (6%)
Query: 193 GCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVL----LEVEGQGGRGRPGQ-SLRRS 247
G RGG R R +R S RG GG+ V L G GRG PG+ L R
Sbjct: 111 GLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGLRRGGVRGRGGPGRGGLGRG 170
Query: 248 GRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGA 283
G G GI R G R RG G GR G GA
Sbjct: 171 AMGRG-GIGGRGRGMIGRGRGGFGGRGRGRGRGRGA 205
>gi|169171347 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1128
Score = 47.0 bits (110), Expect = 4e-05
Identities = 53/156 (33%), Positives = 63/156 (40%), Gaps = 18/156 (11%)
Query: 228 LLEVEGQGGRGRPGQSLRRSG-----RGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEG 282
L E G+G R S + +G GH + RD GG +RG+EG G AG G
Sbjct: 382 LAESRGRGVTPRASWSRQPAGGPLSSEGHLLPLVQRDGGGLAEHRGREGEE--GVRAGGG 439
Query: 283 APHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERAR 342
G R PV G A +GA VRG V ERR E A+
Sbjct: 440 GTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQS-VRGPGV----ERR----VAEGAQ 490
Query: 343 LFHLGRRCALANRAPALLRAQAASAGRDGGGAMASG 378
F G R L A + RAQ A+ GR GGG G
Sbjct: 491 QF--GPRVGLRQHAERVERAQRAAEGRGGGGGGGCG 524
Score = 42.7 bits (99), Expect = 8e-04
Identities = 53/182 (29%), Positives = 68/182 (37%), Gaps = 27/182 (14%)
Query: 128 HRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVA 187
HRGR G +G G R GG G + G GA + G Q G
Sbjct: 425 HRGREGEEGVRAGGGGTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGR----GAQSVRGPG 480
Query: 188 VHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRS 247
V R R G + RVG+R+ A Q EG+GG G G +
Sbjct: 481 VER----RVAEGAQQFGPRVGLRQHAERVERAQR--------AAEGRGGGGGGGCGAQAH 528
Query: 248 GRGHGRGIQARDTGGGPRNRGQ-------EGTHASGRH-AGEGAPHGKLAGVQ--EERVP 297
R G+G Q R G G RG+ +G ++ RH G PH ++ ERVP
Sbjct: 529 RRVVGQG-QVRWEGVGQAARGRRMAHHCSQGRNSQSRHQPGRDRPHHHHLELESLRERVP 587
Query: 298 VE 299
E
Sbjct: 588 CE 589
Score = 35.4 bits (80), Expect = 0.12
Identities = 44/154 (28%), Positives = 56/154 (36%), Gaps = 21/154 (13%)
Query: 99 LRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQT 158
+RA G G GG G RA V G G +V+GP R +G +
Sbjct: 434 VRAGGGGTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQSVRGPGVERRVAEGAQQ-- 491
Query: 159 AAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCG---HVRVGVREQASE 215
G R H ++E A A G GGG CG H RV + Q
Sbjct: 492 ----------FGPRVGLRQHAERVER--AQRAAEGRGGGGGGGCGAQAHRRVVGQGQVRW 539
Query: 216 RGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGR 249
G GQA G+ + +GR QS + GR
Sbjct: 540 EGVGQAARGR----RMAHHCSQGRNSQSRHQPGR 569
Score = 31.2 bits (69), Expect = 2.3
Identities = 35/126 (27%), Positives = 49/126 (38%), Gaps = 15/126 (11%)
Query: 64 SGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGR------QGHGAGGERGGA 117
+G G GR A VR G + + Q G R+ LR R G GG GG
Sbjct: 464 AGAGAAGRGAQSVR-GPGVERRVAEGAQQFGPRVGLRQHAERVERAQRAAEGRGGGGGGG 522
Query: 118 AVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRA 177
R +G+ +G A +G R H QG Q+ RH+ G +P
Sbjct: 523 CGAQAHRRVVGQGQVRWEGVGQAARGRRMAHHCSQGRNSQS-----RHQPGRD---RPHH 574
Query: 178 HGVQIE 183
H +++E
Sbjct: 575 HHLELE 580
>gi|169172209 PREDICTED: hypothetical protein [Homo sapiens]
Length = 801
Score = 47.0 bits (110), Expect = 4e-05
Identities = 53/156 (33%), Positives = 63/156 (40%), Gaps = 18/156 (11%)
Query: 228 LLEVEGQGGRGRPGQSLRRSG-----RGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEG 282
L E G+G R S + +G GH + RD GG +RG+EG G AG G
Sbjct: 55 LAESRGRGVTPRASWSRQPAGGPLSSEGHLLPLVQRDGGGLAEHRGREGEE--GVRAGGG 112
Query: 283 APHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERAR 342
G R PV G A +GA VRG V ERR E A+
Sbjct: 113 GTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQS-VRGPGV----ERR----VAEGAQ 163
Query: 343 LFHLGRRCALANRAPALLRAQAASAGRDGGGAMASG 378
F G R L A + RAQ A+ GR GGG G
Sbjct: 164 QF--GPRVGLRQHAERVERAQRAAEGRGGGGGGGCG 197
Score = 42.7 bits (99), Expect = 8e-04
Identities = 53/182 (29%), Positives = 68/182 (37%), Gaps = 27/182 (14%)
Query: 128 HRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVA 187
HRGR G +G G R GG G + G GA + G Q G
Sbjct: 98 HRGREGEEGVRAGGGGTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGR----GAQSVRGPG 153
Query: 188 VHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRS 247
V R R G + RVG+R+ A Q EG+GG G G +
Sbjct: 154 VER----RVAEGAQQFGPRVGLRQHAERVERAQR--------AAEGRGGGGGGGCGAQAH 201
Query: 248 GRGHGRGIQARDTGGGPRNRGQ-------EGTHASGRH-AGEGAPHGKLAGVQ--EERVP 297
R G+G Q R G G RG+ +G ++ RH G PH ++ ERVP
Sbjct: 202 RRVVGQG-QVRWEGVGQAARGRRMAHHCSQGRNSQSRHQPGRDRPHHHHLELESLRERVP 260
Query: 298 VE 299
E
Sbjct: 261 CE 262
Score = 35.4 bits (80), Expect = 0.12
Identities = 44/154 (28%), Positives = 56/154 (36%), Gaps = 21/154 (13%)
Query: 99 LRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQT 158
+RA G G GG G RA V G G +V+GP R +G +
Sbjct: 107 VRAGGGGTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQSVRGPGVERRVAEGAQQ-- 164
Query: 159 AAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCG---HVRVGVREQASE 215
G R H ++E A A G GGG CG H RV + Q
Sbjct: 165 ----------FGPRVGLRQHAERVER--AQRAAEGRGGGGGGGCGAQAHRRVVGQGQVRW 212
Query: 216 RGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGR 249
G GQA G+ + +GR QS + GR
Sbjct: 213 EGVGQAARGR----RMAHHCSQGRNSQSRHQPGR 242
Score = 31.2 bits (69), Expect = 2.3
Identities = 35/126 (27%), Positives = 49/126 (38%), Gaps = 15/126 (11%)
Query: 64 SGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGR------QGHGAGGERGGA 117
+G G GR A VR G + + Q G R+ LR R G GG GG
Sbjct: 137 AGAGAAGRGAQSVR-GPGVERRVAEGAQQFGPRVGLRQHAERVERAQRAAEGRGGGGGGG 195
Query: 118 AVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRA 177
R +G+ +G A +G R H QG Q+ RH+ G +P
Sbjct: 196 CGAQAHRRVVGQGQVRWEGVGQAARGRRMAHHCSQGRNSQS-----RHQPGRD---RPHH 247
Query: 178 HGVQIE 183
H +++E
Sbjct: 248 HHLELE 253
>gi|169170953 PREDICTED: hypothetical protein [Homo sapiens]
Length = 801
Score = 47.0 bits (110), Expect = 4e-05
Identities = 53/156 (33%), Positives = 63/156 (40%), Gaps = 18/156 (11%)
Query: 228 LLEVEGQGGRGRPGQSLRRSG-----RGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEG 282
L E G+G R S + +G GH + RD GG +RG+EG G AG G
Sbjct: 55 LAESRGRGVTPRASWSRQPAGGPLSSEGHLLPLVQRDGGGLAEHRGREGEE--GVRAGGG 112
Query: 283 APHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERAR 342
G R PV G A +GA VRG V ERR E A+
Sbjct: 113 GTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQS-VRGPGV----ERR----VAEGAQ 163
Query: 343 LFHLGRRCALANRAPALLRAQAASAGRDGGGAMASG 378
F G R L A + RAQ A+ GR GGG G
Sbjct: 164 QF--GPRVGLRQHAERVERAQRAAEGRGGGGGGGCG 197
Score = 42.7 bits (99), Expect = 8e-04
Identities = 53/182 (29%), Positives = 68/182 (37%), Gaps = 27/182 (14%)
Query: 128 HRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVA 187
HRGR G +G G R GG G + G GA + G Q G
Sbjct: 98 HRGREGEEGVRAGGGGTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGR----GAQSVRGPG 153
Query: 188 VHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRS 247
V R R G + RVG+R+ A Q EG+GG G G +
Sbjct: 154 VER----RVAEGAQQFGPRVGLRQHAERVERAQR--------AAEGRGGGGGGGCGAQAH 201
Query: 248 GRGHGRGIQARDTGGGPRNRGQ-------EGTHASGRH-AGEGAPHGKLAGVQ--EERVP 297
R G+G Q R G G RG+ +G ++ RH G PH ++ ERVP
Sbjct: 202 RRVVGQG-QVRWEGVGQAARGRRMAHHCSQGRNSQSRHQPGRDRPHHHHLELESLRERVP 260
Query: 298 VE 299
E
Sbjct: 261 CE 262
Score = 35.4 bits (80), Expect = 0.12
Identities = 44/154 (28%), Positives = 56/154 (36%), Gaps = 21/154 (13%)
Query: 99 LRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQT 158
+RA G G GG G RA V G G +V+GP R +G +
Sbjct: 107 VRAGGGGTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQSVRGPGVERRVAEGAQQ-- 164
Query: 159 AAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCG---HVRVGVREQASE 215
G R H ++E A A G GGG CG H RV + Q
Sbjct: 165 ----------FGPRVGLRQHAERVER--AQRAAEGRGGGGGGGCGAQAHRRVVGQGQVRW 212
Query: 216 RGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGR 249
G GQA G+ + +GR QS + GR
Sbjct: 213 EGVGQAARGR----RMAHHCSQGRNSQSRHQPGR 242
Score = 31.2 bits (69), Expect = 2.3
Identities = 35/126 (27%), Positives = 49/126 (38%), Gaps = 15/126 (11%)
Query: 64 SGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGR------QGHGAGGERGGA 117
+G G GR A VR G + + Q G R+ LR R G GG GG
Sbjct: 137 AGAGAAGRGAQSVR-GPGVERRVAEGAQQFGPRVGLRQHAERVERAQRAAEGRGGGGGGG 195
Query: 118 AVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRA 177
R +G+ +G A +G R H QG Q+ RH+ G +P
Sbjct: 196 CGAQAHRRVVGQGQVRWEGVGQAARGRRMAHHCSQGRNSQS-----RHQPGRD---RPHH 247
Query: 178 HGVQIE 183
H +++E
Sbjct: 248 HHLELE 253
>gi|239508753 PREDICTED: hypothetical protein [Homo sapiens]
Length = 801
Score = 47.0 bits (110), Expect = 4e-05
Identities = 53/156 (33%), Positives = 63/156 (40%), Gaps = 18/156 (11%)
Query: 228 LLEVEGQGGRGRPGQSLRRSG-----RGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEG 282
L E G+G R S + +G GH + RD GG +RG+EG G AG G
Sbjct: 55 LAESRGRGVTPRASWSRQPAGGPLSSEGHLLPLVQRDGGGLAEHRGREGEE--GVRAGGG 112
Query: 283 APHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERAR 342
G R PV G A +GA VRG V ERR E A+
Sbjct: 113 GTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQS-VRGPGV----ERR----VAEGAQ 163
Query: 343 LFHLGRRCALANRAPALLRAQAASAGRDGGGAMASG 378
F G R L A + RAQ A+ GR GGG G
Sbjct: 164 QF--GPRVGLRQHAERVERAQRAAEGRGGGGGGGCG 197
Score = 42.7 bits (99), Expect = 8e-04
Identities = 53/182 (29%), Positives = 68/182 (37%), Gaps = 27/182 (14%)
Query: 128 HRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVA 187
HRGR G +G G R GG G + G GA + G Q G
Sbjct: 98 HRGREGEEGVRAGGGGTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGR----GAQSVRGPG 153
Query: 188 VHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRS 247
V R R G + RVG+R+ A Q EG+GG G G +
Sbjct: 154 VER----RVAEGAQQFGPRVGLRQHAERVERAQR--------AAEGRGGGGGGGCGAQAH 201
Query: 248 GRGHGRGIQARDTGGGPRNRGQ-------EGTHASGRH-AGEGAPHGKLAGVQ--EERVP 297
R G+G Q R G G RG+ +G ++ RH G PH ++ ERVP
Sbjct: 202 RRVVGQG-QVRWEGVGQAARGRRMAHHCSQGRNSQSRHQPGRDRPHHHHLELESLRERVP 260
Query: 298 VE 299
E
Sbjct: 261 CE 262
Score = 35.4 bits (80), Expect = 0.12
Identities = 44/154 (28%), Positives = 56/154 (36%), Gaps = 21/154 (13%)
Query: 99 LRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQT 158
+RA G G GG G RA V G G +V+GP R +G +
Sbjct: 107 VRAGGGGTGEVRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQSVRGPGVERRVAEGAQQ-- 164
Query: 159 AAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCG---HVRVGVREQASE 215
G R H ++E A A G GGG CG H RV + Q
Sbjct: 165 ----------FGPRVGLRQHAERVER--AQRAAEGRGGGGGGGCGAQAHRRVVGQGQVRW 212
Query: 216 RGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGR 249
G GQA G+ + +GR QS + GR
Sbjct: 213 EGVGQAARGR----RMAHHCSQGRNSQSRHQPGR 242
Score = 31.2 bits (69), Expect = 2.3
Identities = 35/126 (27%), Positives = 49/126 (38%), Gaps = 15/126 (11%)
Query: 64 SGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGR------QGHGAGGERGGA 117
+G G GR A VR G + + Q G R+ LR R G GG GG
Sbjct: 137 AGAGAAGRGAQSVR-GPGVERRVAEGAQQFGPRVGLRQHAERVERAQRAAEGRGGGGGGG 195
Query: 118 AVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRA 177
R +G+ +G A +G R H QG Q+ RH+ G +P
Sbjct: 196 CGAQAHRRVVGQGQVRWEGVGQAARGRRMAHHCSQGRNSQS-----RHQPGRD---RPHH 247
Query: 178 HGVQIE 183
H +++E
Sbjct: 248 HHLELE 253
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 46.6 bits (109), Expect = 5e-05
Identities = 57/173 (32%), Positives = 65/173 (37%), Gaps = 32/173 (18%)
Query: 128 HRGRAGGQGGDFAVQGP---RGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEE 184
HRGR GG+GG+ P RG R G GGG R G G V H
Sbjct: 704 HRGR-GGRGGNEPPPPPPPFRGARGGRSGGGPPNG----RGGPGGGMVGGG-GHRPHEGP 757
Query: 185 GVAVHRAGGCRR----GGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRP 240
G + + G R GGG GH G G ++GG EG GG G
Sbjct: 758 GGGMGNSSGHRPHEGPGGGMGSGH--------RPHEGPGGSMGGGGGHRPHEGPGG-GIS 808
Query: 241 GQSLRRSGRGHGRGIQARDTGGGPR-------NRGQEGTHASGRHAGEGAPHG 286
G S R G G G+ A GGG R + G G H G G PHG
Sbjct: 809 GGSGHRPHEGPGGGMGA---GGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHG 858
>gi|239749709 PREDICTED: hypothetical protein [Homo sapiens]
Length = 178
Score = 46.6 bits (109), Expect = 5e-05
Identities = 60/167 (35%), Positives = 72/167 (43%), Gaps = 20/167 (11%)
Query: 217 GHGQA-LGGQDVLLEVEGQGGRGRPGQSLR--RSGRGHGRGIQA---RDTGGGPRNRGQE 270
G G++ LGG V G+G G +R RS R G G +A R GG PR + Q
Sbjct: 10 GRGRSGLGGSGGAPRVRGRGTAVGVGIGVRVWRSRRAEGGGAEAAAARTAGGEPRAQRQA 69
Query: 271 GTHASGRHAGEGAPHGKLAGVQEERVPVEELLARQAR-GEAEARQGALGQVRGGRVRLHR 329
G+ A EG G+ V +VP E L A+ G + QGA Q R H
Sbjct: 70 GSQAD----EEG---GRPERVNHGQVPQGERLRAMAKGGVGKGSQGAERQAS----RPHA 118
Query: 330 ERREGLLARERARLFHLGRRCALA--NRAPALLRAQAASAGRDGGGA 374
E R GL RA RR A A R+P RA AA R GG A
Sbjct: 119 EHRLGLSHLTRAAGAGAARRRAGAARTRSPKGCRAGAARLERAGGPA 165
Score = 30.4 bits (67), Expect = 4.0
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
Query: 440 GLQRPQMRLGPQGGERDAGLGRPHQLIHDRLGQGARQRERRRAVGRQRQRGEERRLVTQH 499
G R Q + G Q E GRP ++ H ++ QG R R + + +G ER+ H
Sbjct: 61 GEPRAQRQAGSQADEEG---GRPERVNHGQVPQGERLRAMAKGGVGKGSQGAERQASRPH 117
Query: 500 RAH 502
H
Sbjct: 118 AEH 120
>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
Length = 819
Score = 46.2 bits (108), Expect = 7e-05
Identities = 85/332 (25%), Positives = 120/332 (36%), Gaps = 56/332 (16%)
Query: 70 GRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFRARVHCHR 129
GRA LG A P++ + A G + G+G ++ +A +
Sbjct: 14 GRAGPGAPLGAALARTPVELAAESAAPALSAAAAGVKILGSGDKK---LRRQKAAAGGKK 70
Query: 130 GRAGGQGGDFAVQGPRGRRH-------GG---QGGGEQTAAVRDRHRDGVGAVAQPRAHG 179
R GQ G AV G R+H GG +GGGEQ AA G G +PR G
Sbjct: 71 ARLRGQKG--AVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLG-GRGRKPRRRG 127
Query: 180 VQIEE-GVAVHR--------AGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLE 230
+ G R AG RG G + GV+ Q E+ A
Sbjct: 128 QKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAA--------- 178
Query: 231 VEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRN-RGQEGTHASGRHAGEGAPHGKLA 289
G + R G+ RR G RG + D G R + + G GR P
Sbjct: 179 --AAGAKSRSGKKPRRRG-AKSRGDE--DKKGRQREAKSRFGKTRGGRRKKHRRPKPAAG 233
Query: 290 GVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRR 349
G + R ++ ++ RG+ A GG+ R+ + R G +L G+
Sbjct: 234 GAKSRRGGGKKPQKQRRRGQKAA--------TGGKSRVGKSRGGG-----DKKLRRQGQN 280
Query: 350 CALA---NRAPALLRAQAASAGRDGGGAMASG 378
ALA R A + A+ GR G G + G
Sbjct: 281 AALAGAKRRGAATAGEKPAAKGRGGRGPKSLG 312
Score = 40.0 bits (92), Expect = 0.005
Identities = 69/271 (25%), Positives = 103/271 (38%), Gaps = 61/271 (22%)
Query: 109 GAGGERGGAAVEFRARVHCHRGRAGGQ--------GGDFAV--QGPRG-----RRHGGQG 153
GA RGG + R + GG+ GGD + QG +R G
Sbjct: 234 GAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAAT 293
Query: 154 GGEQTAAVRDRHRDGVGAVA-------------QPRAHGVQIEEGVAVHRAGGCRRGGGR 200
GE+ AA + R G G + +PR G + + A G +RGGG
Sbjct: 294 AGEKPAA---KGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAA----GTKRGGGG 346
Query: 201 RCGHVRVGVREQASERGHGQ-------------ALGGQDV--LLEVEGQG-GRGRPG-QS 243
+ VGV+ + +R G+ + GG D L E + +G GR +P Q+
Sbjct: 347 QQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQN 406
Query: 244 LRRSGRGHGRGIQARDTGGG---PRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEE 300
RR + + A+ GGG PR RG + + G + G Q+ R E
Sbjct: 407 PRRRAQ---KAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAE 463
Query: 301 LLARQARGEAEARQGALG---QVRGGRVRLH 328
A + + RQ A + RGG ++ H
Sbjct: 464 AGAESRGDKKQGRQKASAAGTKSRGGGLKSH 494
Score = 36.2 bits (82), Expect = 0.073
Identities = 84/346 (24%), Positives = 121/346 (34%), Gaps = 62/346 (17%)
Query: 94 GGRLFLRAEFGRQGHGAGGERGGAAVEFRARVHCHRG-----RAGGQGGDFAVQGPRGRR 148
GG LR + G+ AG +R GAA RG GGQ + G + RR
Sbjct: 269 GGDKKLRRQ-GQNAALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRR 327
Query: 149 HGGQ------------GGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRR 196
G + GGG+Q AAV GV + + R G + A AG R
Sbjct: 328 RGQKATKAAAAGTKRGGGGQQKAAVV-----GVKSRKKQRRRGKKPRRQKA-SAAGAKSR 381
Query: 197 GGG--------RRCGHVRVGVREQ-----------ASERGHGQALGGQDVLLEVEGQGGR 237
GGG +R G R R Q A RG G + + +GG+
Sbjct: 382 GGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGK 441
Query: 238 GRPGQSLRRSGRGHGRGIQARDTGG----------------GPRNRGQEGTHASGRHAGE 281
R G + RG +A + G G ++RG SG++
Sbjct: 442 SRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWR 501
Query: 282 GAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERA 341
+ AG + + +Q R + A GA +V G + R R++ A
Sbjct: 502 RGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSR-QRQKAVAAGATSHG 560
Query: 342 RLFHLGRRCALANRAPALLRAQAASAGRDGGGAMASGIYQRAGIAI 387
+ R N+ P AA+A GGG G +Q+A +
Sbjct: 561 GGGNKQSRGGGGNK-PRQWGQTAAAAKTRGGGDKQPG-WQKAAAGV 604
Score = 33.9 bits (76), Expect = 0.36
Identities = 53/193 (27%), Positives = 72/193 (37%), Gaps = 45/193 (23%)
Query: 104 GRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRD 163
G G+GG++ A A GQ + A + PR RR +G G Q AAV
Sbjct: 650 GATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAE-ARKKPRRRRAKSRGDGGQNAAV-- 706
Query: 164 RHRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALG 223
+ + G + R G R GGG A RG G A
Sbjct: 707 -------GINPWQRRGKK-------PRLGKSRGGGG-------------AKSRGSGGA-- 737
Query: 224 GQDVLLEVEGQGG-RGRPGQSLRRSGRGHGRGIQARDTGGGPRNR-GQEGTHASGRHA-- 279
+ G GG + R G+ S + HG G R GGG ++R G++ A G+ A
Sbjct: 738 ------KSRGSGGAKSRSGKKAAAS-KSHGGGGAKRRRGGGAKSRSGEKAVTAGGQKAAA 790
Query: 280 --GEGAPHGKLAG 290
G+ P K G
Sbjct: 791 AGGKKPPRVKSRG 803
Score = 32.0 bits (71), Expect = 1.4
Identities = 40/157 (25%), Positives = 62/157 (39%), Gaps = 22/157 (14%)
Query: 174 QPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEV-- 231
+P A G + AV + R+ RR +A RG G GQ+ + +
Sbjct: 665 KPAAAGSESSAAAAVGQEAEARKKPRRR----------RAKSRGDG----GQNAAVGINP 710
Query: 232 -EGQGGRGRPGQSLRRSG---RGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGK 287
+ +G + R G+S G RG G G ++R +GG G++ AS H G GA +
Sbjct: 711 WQRRGKKPRLGKSRGGGGAKSRGSG-GAKSRGSGGAKSRSGKKAA-ASKSHGGGGAKRRR 768
Query: 288 LAGVQEERVPVEELLARQARGEAEARQGALGQVRGGR 324
G + Q A ++ + RGGR
Sbjct: 769 GGGAKSRSGEKAVTAGGQKAAAAGGKKPPRVKSRGGR 805
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 45.4 bits (106), Expect = 1e-04
Identities = 71/286 (24%), Positives = 96/286 (33%), Gaps = 69/286 (24%)
Query: 101 AEFGRQG--HGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQT 158
AE RQ H A GG A + R AG + G Q RH G G G+ +
Sbjct: 3592 AESSRQSGTHHAENSSGGQAASSHEQA---RSSAGERHGSHHQQSADSSRHSGIGHGQAS 3648
Query: 159 AAVRDR-HRDGVGAVA-------------------QPRAHGVQIEEGVAVHRAGGCRRGG 198
+AVRD HR G+ A Q H +E AG R G
Sbjct: 3649 SAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSG 3708
Query: 199 G----------RRCGHVRVGV---------REQASERG-HGQALGGQDVLLEVEGQGGRG 238
H R G EQA + H + GQD + G G
Sbjct: 3709 SFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGG 3768
Query: 239 RPG----QSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGR------HAGEGAPHGKL 288
R G QS+ RSG G + GQ G+ ++ R +G+G+ H
Sbjct: 3769 RQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRH--- 3825
Query: 289 AGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREG 334
+G + + +R + Q G+ G R R RR+G
Sbjct: 3826 SGSRHHEASTQADSSRHS-------QSGQGESAGSR----RSRRQG 3860
Score = 42.7 bits (99), Expect = 8e-04
Identities = 63/256 (24%), Positives = 89/256 (34%), Gaps = 64/256 (25%)
Query: 129 RGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDR-HRDGVGAVAQP-RAHGVQIE-EG 185
R AG + G Q RH G G G+ ++AVRD HR G+ A H + +
Sbjct: 2647 RSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQS 2706
Query: 186 VAVHRAGG---------CRRGGGRRCGH-----VRVGVREQA---------SERG----- 217
V+ H G R G GH +V EQ+ S RG
Sbjct: 2707 VSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSR 2766
Query: 218 ---------HGQALGGQDVLLEVEGQGGRGRPG----QSLRRSGRGHGRGIQARDTGGGP 264
H + GQD + G GR G S+ SG G
Sbjct: 2767 HEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSD 2826
Query: 265 RNRGQEGTHASGR------HAGEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALG 318
+RGQ G+ ++ R +G+G+ H +G + ++R + Q G
Sbjct: 2827 ASRGQSGSRSASRTTRNEEQSGDGSRH---SGSRHHEASTHADISRHS-------QAVQG 2876
Query: 319 QVRGGRVRLHRERREG 334
Q G R R RR+G
Sbjct: 2877 QSEGSR----RSRRQG 2888
Score = 40.8 bits (94), Expect = 0.003
Identities = 52/194 (26%), Positives = 68/194 (35%), Gaps = 45/194 (23%)
Query: 129 RGRAGGQGGD-FAVQGPRGRRHGGQGGGEQTAAVRDR-HRDGVGAVAQ------------ 174
R AG + G +Q RH G G G+ ++AVRD HR G+ A
Sbjct: 701 RSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQ 760
Query: 175 ------PRAHGVQIEEGVAVHRAGGCRRGGGRRCGHV---------------RVGVR--- 210
H Q + A R+G R G V GVR
Sbjct: 761 SVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGS 820
Query: 211 --EQASERG-HGQALGGQDVLLEVEGQGGRGRPG----QSLRRSGRGHGRGIQARDTGGG 263
EQA + H + GQD + G RGR G QS+ RSG G
Sbjct: 821 HHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRS 880
Query: 264 PRNRGQEGTHASGR 277
+RGQ G+ ++ R
Sbjct: 881 DASRGQSGSRSASR 894
Score = 40.8 bits (94), Expect = 0.003
Identities = 52/192 (27%), Positives = 69/192 (35%), Gaps = 26/192 (13%)
Query: 101 AEFGRQG--HGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQT 158
AE RQ H A GG A + R AG + G Q RH G G G+ +
Sbjct: 2296 AESSRQSGTHHAENSSGGQAASSHEQA---RSSAGERHGSHHQQSADSSRHSGIGHGQAS 2352
Query: 159 AAVRDR-HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERG 217
+AVRD HR G+ A + + +V G + G + H Q S RG
Sbjct: 2353 SAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHG---QAGPHQQSH-------QESTRG 2402
Query: 218 HGQALGGQ------DVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEG 271
G+ V + + GR G S GR QARD+ + QEG
Sbjct: 2403 RSAGRSGRSGSFLYQVSTHEQSESAHGRTGTS--TGGRQGSHHKQARDS--SRHSTSQEG 2458
Query: 272 THASGRHAGEGA 283
H G +
Sbjct: 2459 QDTIHGHPGSSS 2470
Score = 40.8 bits (94), Expect = 0.003
Identities = 63/245 (25%), Positives = 86/245 (35%), Gaps = 68/245 (27%)
Query: 105 RQGHGAGGER-------------GGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGG 151
R GHG +R GG A + R G + G Q RH G
Sbjct: 3261 RAGHGHSADRSRQSGTRHAETSSGGQAASSHEQA---RSSPGERHGSRHQQSADSSRHSG 3317
Query: 152 QGGGEQTAAVRD-RHRDGVGAVA-QPRAHGVQIE-EGVAVHRAGGCR----------RGG 198
G+ ++AVRD RH G+ A H + + + V+ H G R G
Sbjct: 3318 IPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSG 3377
Query: 199 GR--RCGH--VRVGVREQASERGHGQ------------------------ALGGQDVLLE 230
GR R G +V EQ SE HG+ + GQD +
Sbjct: 3378 GRSGRSGSFLYQVSTHEQ-SESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRG 3436
Query: 231 VEGQGGRGRPG----QSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGR------HAG 280
G RGR G QS+ RSG G +RGQ G+ ++ R +G
Sbjct: 3437 HPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSG 3496
Query: 281 EGAPH 285
+G+ H
Sbjct: 3497 DGSRH 3501
Score = 37.4 bits (85), Expect = 0.033
Identities = 52/215 (24%), Positives = 72/215 (33%), Gaps = 31/215 (14%)
Query: 128 HRGRAG-GQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGV 186
H RAG G D + Q G RH G Q A+ ++ R G HG + ++
Sbjct: 3258 HEDRAGHGHSADRSRQS--GTRHAETSSGGQAASSHEQARSSPG-----ERHGSRHQQSA 3310
Query: 187 AVHRAGGCRRGGG----RRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQ 242
R G RG R H + + GH + Q V G G G Q
Sbjct: 3311 DSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSV----SGHGQAGPHQQ 3366
Query: 243 SLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELL 302
S + S ARD GG R + H + HG+ R
Sbjct: 3367 SHQES---------ARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQ 3417
Query: 303 ARQARGEAEARQGA------LGQVRGGRVRLHRER 331
AR + + +++G G R GR H E+
Sbjct: 3418 ARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQ 3452
Score = 37.0 bits (84), Expect = 0.043
Identities = 57/230 (24%), Positives = 77/230 (33%), Gaps = 57/230 (24%)
Query: 108 HGAGGERGGAAVEFRARVHCHRGRAGGQ-GGDFAVQGPRGRRHGGQGGGEQTAAVRDR-H 165
H RG AA R AG + G +Q RH G G G+ ++AVRD H
Sbjct: 1981 HTESSSRGQAASSHEQA----RSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGH 2036
Query: 166 RDGVGAVAQPRAHGVQIEEGVAVHRAG-----------GCRRGGGRRCGH-----VRVGV 209
R G+ A + + +V G R G G +V
Sbjct: 2037 RGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVST 2096
Query: 210 REQASERGHGQAL------------------------GGQDVLLEVEGQGGRGRPG---- 241
EQ SE HGQ+ GQD + G GR G
Sbjct: 2097 HEQ-SESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQE 2155
Query: 242 QSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGR------HAGEGAPH 285
QS+ RSG G +RGQ G+ ++ R +G+G+ H
Sbjct: 2156 QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRH 2205
Score = 37.0 bits (84), Expect = 0.043
Identities = 49/193 (25%), Positives = 66/193 (34%), Gaps = 44/193 (22%)
Query: 129 RGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDR-HRDGVGAVAQP-RAHGVQIE-EG 185
R AG + G Q RH G G G+ ++AVRD HR G+ A H + +
Sbjct: 2971 RSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQS 3030
Query: 186 VAVHRAGG---------CRRGGGRRCGH-----VRVGVREQA---------SERG----- 217
V+ H G R G GH +V EQ+ S RG
Sbjct: 3031 VSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSR 3090
Query: 218 ---------HGQALGGQDVLLEVEGQGGRGRPG----QSLRRSGRGHGRGIQARDTGGGP 264
H + GQD + G GR G S+ SG G
Sbjct: 3091 HEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSD 3150
Query: 265 RNRGQEGTHASGR 277
+RGQ G+ ++ R
Sbjct: 3151 ASRGQSGSRSASR 3163
Score = 34.7 bits (78), Expect = 0.21
Identities = 59/270 (21%), Positives = 87/270 (32%), Gaps = 37/270 (13%)
Query: 106 QGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRH 165
+GH G RGG + G +G QG HG G + R+
Sbjct: 517 RGH-PGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEE 575
Query: 166 RDGVGA-VAQPRAHGVQIEEGVAVHRAGGCRRGGGRRC---------------GHVRVGV 209
+ G G + R H + + H G + G R GH
Sbjct: 576 QSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSE 635
Query: 210 R--EQASERGHGQAL-----GGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGI------- 255
R AS HG A G + E + G G S R+SG H +
Sbjct: 636 RWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAAS 695
Query: 256 ---QARDTGGGPR-NRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLARQARGEAE 311
QAR + G +R Q + S RH+G G HG+ + + ++ E
Sbjct: 696 SHEQARSSAGERHGSRHQLQSADSSRHSGTG--HGQASSAVRDSGHRGSSGSQATDSEGH 753
Query: 312 ARQGALGQVRGGRVRLHRERREGLLARERA 341
+ V G H ++ AR+R+
Sbjct: 754 SEDSDTQSVSGHGQAGHHQQSHQESARDRS 783
Score = 34.7 bits (78), Expect = 0.21
Identities = 48/209 (22%), Positives = 66/209 (31%), Gaps = 20/209 (9%)
Query: 128 HRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVA 187
H+ G G G RH G Q A+ ++ R G HG ++
Sbjct: 2933 HQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAG-----ERHGSHHQQSAD 2987
Query: 188 VHRAGGCRRGGG----RRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQS 243
R G G R GH + + GH + Q V GQ G S
Sbjct: 2988 SSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSV--SAHGQAG------S 3039
Query: 244 LRRSGRGHGRGIQARDTGGGPRNRGQEGTH--ASGRHAGEGAPHGKLAGVQEERVPVEEL 301
++S + RG +G Q TH + H G G + E+
Sbjct: 3040 HQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR 3099
Query: 302 LARQARGEAEARQGALGQVRGGRVRLHRE 330
+ G+ R G G RGGR H E
Sbjct: 3100 HSASQYGQDTIR-GHPGSSRGGRQGYHHE 3127
Score = 33.9 bits (76), Expect = 0.36
Identities = 72/339 (21%), Positives = 111/339 (32%), Gaps = 46/339 (13%)
Query: 60 DSDVSGTGLRGRAAGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAV 119
DSD G+A + ++A G + +Q + G G +
Sbjct: 756 DSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTG-PST 814
Query: 120 EFRARVHCHRGR-----AGGQGGDFAVQG-PRGRRHGGQGGGEQTAAVRDRHRDGVGA-- 171
R H + R + Q G ++G P R G QG + + R H +
Sbjct: 815 GVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHT 874
Query: 172 VAQPRAHGVQIEEGVA----VHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDV 227
+Q R+ + + G R R G R G A H QA GQ
Sbjct: 875 TSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQS- 933
Query: 228 LLEVEGQGGRGRPGQSLRRSGRGHGR--------GIQARDTGGGPRNRGQEGTHASGRHA 279
EG R G S+ + G G +R+ G + + + G+ H
Sbjct: 934 ----EGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHH 989
Query: 280 GEGAPHGKLAGVQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARE 339
+ A HG A + G A + GQ H + R R
Sbjct: 990 EDRAGHGHSADSSRQS------------GTPHAETSSGGQAASS----HEQARSSPGERH 1033
Query: 340 RARLFHLGRRCALANRAPALLRAQAASAGRDGGGAMASG 378
+R ++ A ++R + R QA+SA RD G +SG
Sbjct: 1034 GSR----HQQSADSSRHSGIPRRQASSAVRDSGHWGSSG 1068
Score = 33.1 bits (74), Expect = 0.62
Identities = 45/217 (20%), Positives = 66/217 (30%), Gaps = 21/217 (9%)
Query: 111 GGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVG 170
G RGG + G +G QG HG G + R + G G
Sbjct: 1170 GSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDG 1229
Query: 171 AVAQPRAH--GVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVL 228
+ H + + G + G R H V + + H D
Sbjct: 1230 SRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERH------SDDS 1283
Query: 229 LEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHA-----SGRHAGEGA 283
+ G R G S +S G +R G +R G A SG H E +
Sbjct: 1284 ERLSGSASRNHHGSSREQSRDG------SRHPGFHQEDRASHGHSADSSRQSGTHHTESS 1337
Query: 284 PHGKLAGVQEE--RVPVEELLARQARGEAEARQGALG 318
HG+ E+ P E +R + +R +G
Sbjct: 1338 SHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIG 1374
Score = 32.7 bits (73), Expect = 0.80
Identities = 42/187 (22%), Positives = 63/187 (33%), Gaps = 31/187 (16%)
Query: 122 RARVHCHRGRAGGQGGDFAV----QGPRGRRHGGQGGGEQTAAVRDRHRDGVGA------ 171
+ R RG++G + Q G RH G E ++ VG
Sbjct: 2174 QGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGP 2233
Query: 172 -VAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLE 230
++PR V + H RR G H +EQ+ + G +
Sbjct: 2234 RTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNH-HGSAQEQSRD-------GSRHPRSH 2285
Query: 231 VEGQGGRGRPGQSLRRSGRGHGRGI----------QARDTGGGPRNRGQEGTHASGRHAG 280
E + G G +S R+SG H QAR + G + + S RH+G
Sbjct: 2286 HEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSG 2345
Query: 281 EGAPHGK 287
G HG+
Sbjct: 2346 IG--HGQ 2350
Score = 32.7 bits (73), Expect = 0.80
Identities = 50/217 (23%), Positives = 70/217 (32%), Gaps = 39/217 (17%)
Query: 104 GRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRD 163
G G +GG +G + R G +G QG HG G + R+
Sbjct: 2464 GHPGSSSGGRQGSHYEQLVDR----SGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRN 2519
Query: 164 RHRDGVGA-VAQPRAHGVQIEEGVAVHRAGGCRRGGGRRC---------------GHVRV 207
+ G G+ + R H + H G + G R GH
Sbjct: 2520 DEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSED 2579
Query: 208 GVR--EQASERGHGQAL-----GGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGI----- 255
R AS HG A G + E + G G S R+SG H +
Sbjct: 2580 SERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQA 2639
Query: 256 -----QARDTGGGPRNRGQEGTHASGRHAGEGAPHGK 287
QAR + G + + S RH+G G HG+
Sbjct: 2640 ASSHEQARSSAGERHGSHHQQSADSSRHSGIG--HGQ 2674
Score = 32.3 bits (72), Expect = 1.1
Identities = 44/193 (22%), Positives = 63/193 (32%), Gaps = 29/193 (15%)
Query: 106 QGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRH 165
+GH G RGG + + G +G QG HG G + R+
Sbjct: 1490 RGH-PGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEE 1548
Query: 166 RDGVGA-VAQPRAHGVQIEEGVAVHRAGGCRRGGGRRC---------------GHVRVGV 209
+ G G+ + R H G + H G G + GH
Sbjct: 1549 QSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSE 1608
Query: 210 R--EQASERGHGQAL-----GGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGG 262
R E AS +G A G ++ E + G +S R+SG H A + G
Sbjct: 1609 RRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRH-----AETSSG 1663
Query: 263 GPRNRGQEGTHAS 275
G QE +S
Sbjct: 1664 GQAASSQEQARSS 1676
Score = 31.6 bits (70), Expect = 1.8
Identities = 51/222 (22%), Positives = 70/222 (31%), Gaps = 34/222 (15%)
Query: 95 GRLFLRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQ-- 152
G+ +R G G G +V+ H QG A +G G R +
Sbjct: 3430 GQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQT 3489
Query: 153 ------GGGEQ----------TAAVRDRH-RDGVGAVAQPRAHGVQIEEGVAVHRAGGCR 195
G G + T A RH + G G A PR Q + G
Sbjct: 3490 RNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHS 3549
Query: 196 RGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHGRGI 255
R G R A E+ G + E + G G +S R+SG H
Sbjct: 3550 EDSERWSGSASRNHRGSAQEQSRD---GSRHPTSHHEDRAGHGHSAESSRQSGTHHAENS 3606
Query: 256 ----------QARDTGGGPRNRGQEGTHASGRHAGEGAPHGK 287
QAR + G + + S RH+G G HG+
Sbjct: 3607 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIG--HGQ 3646
Score = 30.8 bits (68), Expect = 3.1
Identities = 41/169 (24%), Positives = 53/169 (31%), Gaps = 30/169 (17%)
Query: 109 GAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDG 168
G GER G + F +V H G R G GG Q R RH
Sbjct: 1753 GQSGERSGRSGSFLYQVSTHEQSESAHG-----------RTGPSTGGRQ----RSRHEQ- 1796
Query: 169 VGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVL 228
A+ + +EG R GGR+ H V H Q+
Sbjct: 1797 ----ARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERS 1852
Query: 229 LEVEGQGGRGRPGQSLRRSGRGHGRGIQARDTGGGPRNRGQEGTHASGR 277
GQ G +S+ R R + +G G R+ G AS R
Sbjct: 1853 DVSRGQSG----SRSVSRQTRNE------KQSGDGSRHSGSRHHEASSR 1891
Score = 30.4 bits (67), Expect = 4.0
Identities = 58/268 (21%), Positives = 88/268 (32%), Gaps = 32/268 (11%)
Query: 114 RGGAAVEFRARVHCHRG-RAGGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAV 172
R A+ E + + H G R GG+ G Q H G T+ R G
Sbjct: 1154 RHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHG---- 1209
Query: 173 AQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVE 232
Q + + G R G R + S+ G Q+ G +
Sbjct: 1210 -QSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTS----R 1264
Query: 233 GQGGRGRPGQSLRRSGRGHGR--GIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAG 290
QG R R G +R+ G R + ++G+ G H + A HG A
Sbjct: 1265 HQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSAD 1324
Query: 291 VQEERVPVEELLARQARGEAEARQGALGQVRGGRVRLHRERREGLLARERARLFHLGRRC 350
+ + G + GQ V H + R R +R ++
Sbjct: 1325 ------------SSRQSGTHHTESSSHGQA----VSSHEQARSSPGERHGSR----HQQS 1364
Query: 351 ALANRAPALLRAQAASAGRDGGGAMASG 378
A ++R + QA+SA RD G +SG
Sbjct: 1365 ADSSRHSGIGHRQASSAVRDSGHRGSSG 1392
>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
Length = 398
Score = 45.1 bits (105), Expect = 2e-04
Identities = 64/252 (25%), Positives = 88/252 (34%), Gaps = 30/252 (11%)
Query: 73 AGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRA 132
A VR +Q A + +GG ++ G G G G GG + VH + G +
Sbjct: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNP-GGLGTPW---VHGYPGNS 180
Query: 133 GGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAG 192
G G P G+ GG GG + GAVAQP V+ A ++
Sbjct: 181 AGSFGMNPQGAPWGQ--GGNGGPPNFGT------NTQGAVAQPGYGSVR-----ASNQNE 227
Query: 193 GCRR----GGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSG 248
GC G G + G Q+ G G + G G S SG
Sbjct: 228 GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG 287
Query: 249 RGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLARQARG 308
G +R G + G +SG H G G +G G ++ +ARG
Sbjct: 288 GSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP--------GNEARG 339
Query: 309 EAEAR-QGALGQ 319
E+ QG GQ
Sbjct: 340 SGESGIQGFRGQ 351
>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
Length = 416
Score = 45.1 bits (105), Expect = 2e-04
Identities = 64/252 (25%), Positives = 88/252 (34%), Gaps = 30/252 (11%)
Query: 73 AGPVRLGFQAANQPLDALQFAGGRLFLRAEFGRQGHGAGGERGGAAVEFRARVHCHRGRA 132
A VR +Q A + +GG ++ G G G G GG + VH + G +
Sbjct: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNP-GGLGTPW---VHGYPGNS 180
Query: 133 GGQGGDFAVQGPRGRRHGGQGGGEQTAAVRDRHRDGVGAVAQPRAHGVQIEEGVAVHRAG 192
G G P G+ GG GG + GAVAQP V+ A ++
Sbjct: 181 AGSFGMNPQGAPWGQ--GGNGGPPNFGT------NTQGAVAQPGYGSVR-----ASNQNE 227
Query: 193 GCRR----GGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSG 248
GC G G + G Q+ G G + G G S SG
Sbjct: 228 GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG 287
Query: 249 RGHGRGIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEELLARQARG 308
G +R G + G +SG H G G +G G ++ +ARG
Sbjct: 288 GSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP--------GNEARG 339
Query: 309 EAEAR-QGALGQ 319
E+ QG GQ
Sbjct: 340 SGESGIQGFRGQ 351
>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
Length = 2263
Score = 44.7 bits (104), Expect = 2e-04
Identities = 55/215 (25%), Positives = 77/215 (35%), Gaps = 35/215 (16%)
Query: 95 GRLFLRAEFGRQG----HGAGGERGGAAVEFRARVHCHRGRAGGQGGDFAVQGPRGRR-- 148
GR + + G QG G G+RG + RG G G D +++GP G +
Sbjct: 1479 GRKGEKGDEGSQGSPGKRGTPGDRGAKGL---------RGDPGAPGVDSSIEGPTGLKGE 1529
Query: 149 HGGQG-----------GGEQTAAVRDR--HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCR 195
G QG G + A R H G P G +E + + G R
Sbjct: 1530 RGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDG--LEGSLGLKGPQGPR 1587
Query: 196 RGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQSLRRSGRGHG--R 253
G + VG + G G G Q L QG +G PG + G R
Sbjct: 1588 GEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRL---GSQGNKGEPGDLGEKGAVGFPGPR 1644
Query: 254 GIQARDTGGGPRNRGQEGTHASGRHAGEGAPHGKL 288
G+Q D G + G++G GE P G++
Sbjct: 1645 GLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEI 1679
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,103,879
Number of Sequences: 37866
Number of extensions: 1228514
Number of successful extensions: 7299
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 317
Number of HSP's that attempted gapping in prelim test: 5538
Number of HSP's gapped (non-prelim): 1471
length of query: 510
length of database: 18,247,518
effective HSP length: 107
effective length of query: 403
effective length of database: 14,195,856
effective search space: 5720929968
effective search space used: 5720929968
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.