Search of human proteins with 239750339

Search of human proteins with 239750339

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239750339 PREDICTED: hypothetical protein XP_002347374 [Homo
sapiens]
         (183 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239750339 PREDICTED: hypothetical protein XP_002347374 [Homo ...   375   e-105
gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprot...   360   e-100
gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein ...   102   2e-22
gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [H...    87   1e-17
gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]     86   2e-17
gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]    85   3e-17
gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]    84   7e-17
gi|112382270 matrix metalloproteinase 17 preproprotein [Homo sap...    82   2e-16
gi|73808268 matrix metalloproteinase 27 [Homo sapiens]                 82   3e-16
gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]       80   1e-15
gi|11968059 matrix metalloproteinase 25 preproprotein [Homo sapi...    79   2e-15
gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]    78   4e-15
gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]    77   8e-15
gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]    77   8e-15
gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein...    76   1e-14
gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein ...    76   1e-14
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]       75   2e-14
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [...    75   2e-14
gi|73858572 matrix metalloproteinase 12 preproprotein [Homo sapi...    73   1e-13
gi|58331148 matrix metalloproteinase 11 preproprotein [Homo sapi...    71   6e-13
gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]    70   1e-12
gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]     68   5e-12
gi|73808266 matrix metalloproteinase 26 preproprotein [Homo sapi...    68   5e-12
gi|45359865 matrix metalloproteinase 20 preproprotein [Homo sapi...    65   2e-11
gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]     64   6e-11
gi|22218341 matrix metalloproteinase 21 preproprotein [Homo sapi...    64   6e-11
gi|73808271 matrix metalloproteinase 28 isoform 3 [Homo sapiens]       51   6e-07
gi|5902004 matrix metalloproteinase 23B precursor [Homo sapiens]       51   6e-07
gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens]           30   1.2  
gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens]           30   1.2  

>gi|239750339 PREDICTED: hypothetical protein XP_002347374 [Homo
           sapiens]
          Length = 183

 Score =  375 bits (964), Expect = e-105
 Identities = 183/183 (100%), Positives = 183/183 (100%)

Query: 1   MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF 60
           MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF
Sbjct: 1   MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF 60

Query: 61  QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTL 120
           QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTL
Sbjct: 61  QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTL 120

Query: 121 PPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRQQFSV 180
           PPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRQQFSV
Sbjct: 121 PPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRQQFSV 180

Query: 181 PTS 183
           PTS
Sbjct: 181 PTS 183


>gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprotein
           [Homo sapiens]
          Length = 508

 Score =  360 bits (924), Expect = e-100
 Identities = 175/175 (100%), Positives = 175/175 (100%)

Query: 1   MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF 60
           MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF
Sbjct: 1   MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF 60

Query: 61  QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTL 120
           QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTL
Sbjct: 61  QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTL 120

Query: 121 PPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGR 175
           PPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGR
Sbjct: 121 PPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGR 175


>gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein
           [Homo sapiens]
          Length = 520

 Score =  102 bits (253), Expect = 2e-22
 Identities = 64/166 (38%), Positives = 91/166 (54%), Gaps = 24/166 (14%)

Query: 31  YLSQYGYLQKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDP 90
           +L +YGYL + +  +        ++A+RAFQ  S+LPVSG LD AT  +M +PRCG+ D 
Sbjct: 39  FLEKYGYLNEQVPKAPT--STRFSDAIRAFQWVSQLPVSGVLDRATLRQMTRPRCGVTDT 96

Query: 91  FN-------------------QKTLKYLLLG-RWRKKHLTFRILNLPSTLPPHTARAALR 130
            +                   ++  ++   G +W K+HL++R++N P  LP    R A+R
Sbjct: 97  NSYAAWAERISDLFARHRTKMRRKKRFAKQGNKWYKQHLSYRLVNWPEHLPEPAVRGAVR 156

Query: 131 QAFQDWSNVAPLTFQEVQA-GAADIRLS-FHGRQSSYCSNTFDGPG 174
            AFQ WSNV+ L F E  A G ADIRL+ F G  +    N FDGPG
Sbjct: 157 AAFQLWSNVSALEFWEAPATGPADIRLTFFQGDHNDGLGNAFDGPG 202


>gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [Homo
           sapiens]
          Length = 469

 Score = 86.7 bits (213), Expect = 1e-17
 Identities = 59/150 (39%), Positives = 80/150 (53%), Gaps = 14/150 (9%)

Query: 31  YLSQYGYLQ---KPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGL 87
           YL +Y  L+   + +E   N  P  + E L+  QE   L V+G+ D  T   M+QPRCG+
Sbjct: 37  YLEKYYNLKNDGRQVEKRRNSGP--VVEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGV 94

Query: 88  EDPFNQKTLKYLLLG---RWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTF 144
            D       +++L     RW + HLT+RI N    LP      A+ +AFQ WSNV PLTF
Sbjct: 95  PD-----VAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTF 149

Query: 145 QEVQAGAADIRLSFHGRQSSYCSNTFDGPG 174
            +V  G ADI +SF  R     ++ FDGPG
Sbjct: 150 TKVSEGQADIMISF-VRGDHRDNSPFDGPG 178


>gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]
          Length = 477

 Score = 85.5 bits (210), Expect = 2e-17
 Identities = 53/145 (36%), Positives = 77/145 (53%), Gaps = 4/145 (2%)

Query: 31  YLSQYGYLQKPLEGSNNFKPED-ITEALRAFQEASELPVSGQLDDATRARMRQPRCGLED 89
           YL  Y  L+K ++     K    + + +R  Q+   L V+G+LD  T   MR+PRCG+ D
Sbjct: 37  YLENYYDLKKDVKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPD 96

Query: 90  PFNQKTLKYLLLGRWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQA 149
             + +T   +   +WRK HLT+RI+N    LP     +A+ +A + W  V PLTF  +  
Sbjct: 97  VGHFRTFPGI--PKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYE 154

Query: 150 GAADIRLSFHGRQSSYCSNTFDGPG 174
           G ADI +SF  R+       FDGPG
Sbjct: 155 GEADIMISFAVREHG-DFYPFDGPG 178


>gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]
          Length = 476

 Score = 85.1 bits (209), Expect = 3e-17
 Identities = 50/144 (34%), Positives = 77/144 (53%), Gaps = 3/144 (2%)

Query: 31  YLSQYGYLQKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDP 90
           YL +Y  L+K ++         I + ++  Q+   L V+G+LD  T   MR+PRCG+ D 
Sbjct: 37  YLEKYYNLEKDVKQFRRKDSNLIVKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDV 96

Query: 91  FNQKTLKYLLLGRWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAG 150
            +  +   +   +WRK HLT+RI+N    LP     +A+ +A + W  V PLTF  +  G
Sbjct: 97  GHFSSFPGM--PKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEG 154

Query: 151 AADIRLSFHGRQSSYCSNTFDGPG 174
            ADI +SF  ++      +FDGPG
Sbjct: 155 EADIMISFAVKEHG-DFYSFDGPG 177


>gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]
          Length = 669

 Score = 84.0 bits (206), Expect = 7e-17
 Identities = 61/175 (34%), Positives = 82/175 (46%), Gaps = 31/175 (17%)

Query: 24  AEVAPVDYLSQYGYLQKPLEGSNNFKPEDI-TEALRAFQEASELPVSGQLDDATRARMRQ 82
           AEV   ++L  YGYL +P    +  +   I   AL   Q    +PV+G LD+ T+  M++
Sbjct: 49  AEVHAENWLRLYGYLPQPSRHMSTMRSAQILASALAEMQRFYGIPVTGVLDEETKEWMKR 108

Query: 83  PRCGLEDPFN--------QKTLKYLLLGR-WRKKHLTFRILNLPSTLPPHTARAALRQAF 133
           PRCG+ D F         ++  +Y L GR W   HLTF I N    L  + +  A+R+AF
Sbjct: 109 PRCGVPDQFGVRVKANLRRRRKRYALTGRKWNNHHLTFSIQNYTEKLGWYHSMEAVRRAF 168

Query: 134 QDWSNVAPLTFQEVQAGAADIRL--------------SFHGRQSSYCSNTFDGPG 174
           + W    PL FQEV     DIRL               FHG      S+ FDG G
Sbjct: 169 RVWEQATPLVFQEVP--YEDIRLRRQKEADIMVLFASGFHGD-----SSPFDGTG 216


>gi|112382270 matrix metalloproteinase 17 preproprotein [Homo
           sapiens]
          Length = 603

 Score = 82.4 bits (202), Expect = 2e-16
 Identities = 54/154 (35%), Positives = 84/154 (54%), Gaps = 10/154 (6%)

Query: 29  VDYLSQYGYLQK--PLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCG 86
           V++LS++GYL    P  G    + E++++A+ A Q+   L  +G LD+AT A M+ PRC 
Sbjct: 53  VEWLSRFGYLPPADPTTGQLQTQ-EELSKAITAMQQFGGLEATGILDEATLALMKTPRCS 111

Query: 87  LED----PFNQKTLKYLLLGRWRKKHLTFRILNLP--STLPPHTARAALRQAFQDWSNVA 140
           L D       ++  +     +W K++L++R+   P  S L   T RA +  A + WS++A
Sbjct: 112 LPDLPVLTQARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIA 171

Query: 141 PLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPG 174
           PL F EV   AADI++ F  +        FDGPG
Sbjct: 172 PLNFHEVAGSAADIQIDF-SKADHNDGYPFDGPG 204


>gi|73808268 matrix metalloproteinase 27 [Homo sapiens]
          Length = 513

 Score = 82.0 bits (201), Expect = 3e-16
 Identities = 61/170 (35%), Positives = 90/170 (52%), Gaps = 21/170 (12%)

Query: 11  LLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPED---ITEALRAFQEASELP 67
           L+ MT +   + LA+     YL+Q+  L+  +EG++  + ++   I + +R  Q    L 
Sbjct: 20  LVRMTENEENMQLAQA----YLNQFYSLE--IEGNHLVQSKNRSLIDDKIREMQAFFGLT 73

Query: 68  VSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTLPPHTARA 127
           V+G+LD  T   M+ PRCG+ D        Y L G WRK +LT+RI+N      P  ARA
Sbjct: 74  VTGKLDSNTLEIMKTPRCGVPDVGQYG---YTLPG-WRKYNLTYRIIN----YTPDMARA 125

Query: 128 ALRQAFQD----WSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGP 173
           A+ +A Q+    WS V PL F ++  G ADI ++F  R    C   FDGP
Sbjct: 126 AVDEAIQEGLEVWSKVTPLKFTKISKGIADIMIAFRTRVHGRCPRYFDGP 175


>gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]
          Length = 403

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 50/117 (42%), Positives = 65/117 (55%), Gaps = 9/117 (7%)

Query: 61  QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLG---RWRKKHLTFRILNLP 117
           QE   L V+G+ D  T   M+QPRCG+ D       +++L     RW + HLT+RI N  
Sbjct: 2   QEFFGLKVTGKPDAETLKVMKQPRCGVPD-----VAQFVLTEGNPRWEQTHLTYRIENYT 56

Query: 118 STLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPG 174
             LP      A+ +AFQ WSNV PLTF +V  G ADI +SF  R     ++ FDGPG
Sbjct: 57  PDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISF-VRGDHRDNSPFDGPG 112


>gi|11968059 matrix metalloproteinase 25 preproprotein [Homo
           sapiens]
          Length = 562

 Score = 79.3 bits (194), Expect = 2e-15
 Identities = 55/158 (34%), Positives = 79/158 (50%), Gaps = 13/158 (8%)

Query: 29  VDYLSQYGYLQKPLEGSNNFK-PEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGL 87
           VD+L++YGYL  P       + PE + +A++  Q  + LP +G++D  T A MR+PRC L
Sbjct: 33  VDWLTRYGYLPPPHPAQAQLQSPEKLRDAIKVMQRFAGLPETGRMDPGTVATMRKPRCSL 92

Query: 88  EDPFN-----QKTLKYLLLGR-WRKKHLTFRILNLP--STLPPHTARAALRQAFQDWSNV 139
            D        ++  +Y L G  W+K+ LT+R+ + P  S L   T R  +  A   W   
Sbjct: 93  PDVLGVAGLVRRRRRYALSGSVWKKRTLTWRVRSFPQSSQLSQETVRVLMSYALMAWGME 152

Query: 140 APLTFQEV---QAGAADIRLSFHGRQSSYCSNTFDGPG 174
           + LTF EV   Q    DI + F  R     S  FDG G
Sbjct: 153 SGLTFHEVDSPQGQEPDILIDF-ARAFHQDSYPFDGLG 189


>gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]
          Length = 645

 Score = 78.2 bits (191), Expect = 4e-15
 Identities = 57/168 (33%), Positives = 80/168 (47%), Gaps = 22/168 (13%)

Query: 24  AEVAPVDYLSQYGYLQK-PLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQ 82
           A  A  ++L  YGYL       S     + +  A+   Q+   +PV+G LD  T   M++
Sbjct: 77  APFAGQNWLKSYGYLLPYDSRASALHSAKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKK 136

Query: 83  PRCGLED----PFNQKTLKYLLLG-RWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWS 137
           PRCG+ D       ++  +Y L G +WR+KH+T+ I N    +     R A+RQAF  W 
Sbjct: 137 PRCGVPDHPHLSRRRRNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQ 196

Query: 138 NVAPLTFQEV-------QAGAADIRL----SFHGRQSSYCSNTFDGPG 174
            V PLTF+EV           ADI +     FHG      S+ FDG G
Sbjct: 197 KVTPLTFEEVPYHEIKSDRKEADIMIFFASGFHGD-----SSPFDGEG 239


>gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]
          Length = 582

 Score = 77.0 bits (188), Expect = 8e-15
 Identities = 59/190 (31%), Positives = 86/190 (45%), Gaps = 31/190 (16%)

Query: 11  LLPMTVSGRVLGL------AEVAPVDYLSQYGYLQK-PLEGSNNFKPEDITEALRAFQEA 63
           LLP+   G  L        +  +P  +L QYGYL    L       P+ ++ A+ A Q+ 
Sbjct: 12  LLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQSLSAAIAAMQKF 71

Query: 64  SELPVSGQLDDATRARMRQPRCGLEDPF------NQKTLKYLLLG-RWRKKHLTFRILNL 116
             L V+G+ D  T   MR+PRCG+ D F      N +  +Y + G +W+   +TF I N 
Sbjct: 72  YGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQHNEITFCIQNY 131

Query: 117 PSTLPPHTARAALRQAFQDWSNVAPLTFQEV--------QAGAADIRL----SFHGRQSS 164
              +  +    A+R+AF+ W +  PL F+EV            ADI +     FHG    
Sbjct: 132 TPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIFFAEGFHGD--- 188

Query: 165 YCSNTFDGPG 174
             S  FDG G
Sbjct: 189 --STPFDGEG 196


>gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]
          Length = 471

 Score = 77.0 bits (188), Expect = 8e-15
 Identities = 46/121 (38%), Positives = 64/121 (52%), Gaps = 3/121 (2%)

Query: 53  ITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFR 112
           +TE LR  Q    L V+G+LDD T   M++PRCG+ D          L  +W K +LT+R
Sbjct: 64  MTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFPRTL--KWSKMNLTYR 121

Query: 113 ILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDG 172
           I+N    +       A ++AF+ WS+V PL F  +  G ADI +SF G +       FDG
Sbjct: 122 IVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISF-GIKEHGDFYPFDG 180

Query: 173 P 173
           P
Sbjct: 181 P 181


>gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein
           [Homo sapiens]
          Length = 457

 Score = 76.3 bits (186), Expect = 1e-14
 Identities = 53/163 (32%), Positives = 84/163 (51%), Gaps = 24/163 (14%)

Query: 31  YLSQYGYLQKPLEGSNNFKP-EDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLED 89
           +L +YGYL       +  +  E +  AL A Q+   + ++G++D  T   M++PRCG+ D
Sbjct: 46  WLQKYGYLPPTDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPD 105

Query: 90  P------FNQKTLKYLLLG-RWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPL 142
                  F+ +  +Y L G +W+ KH+T+ I N+   +     R A+R+AF  W NV PL
Sbjct: 106 QTRGSSKFHIRRKRYALTGQKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPL 165

Query: 143 TFQEV-----QAGAADIRLS------FHGRQSSYCSNTFDGPG 174
           TF+EV     + G  D+ ++      FHG      S+ FDG G
Sbjct: 166 TFEEVPYSELENGKRDVDITIIFASGFHGD-----SSPFDGEG 203


>gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein
           [Homo sapiens]
          Length = 607

 Score = 76.3 bits (186), Expect = 1e-14
 Identities = 53/163 (32%), Positives = 84/163 (51%), Gaps = 24/163 (14%)

Query: 31  YLSQYGYLQKPLEGSNNFKP-EDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLED 89
           +L +YGYL       +  +  E +  AL A Q+   + ++G++D  T   M++PRCG+ D
Sbjct: 46  WLQKYGYLPPTDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPD 105

Query: 90  P------FNQKTLKYLLLG-RWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPL 142
                  F+ +  +Y L G +W+ KH+T+ I N+   +     R A+R+AF  W NV PL
Sbjct: 106 QTRGSSKFHIRRKRYALTGQKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPL 165

Query: 143 TFQEV-----QAGAADIRLS------FHGRQSSYCSNTFDGPG 174
           TF+EV     + G  D+ ++      FHG      S+ FDG G
Sbjct: 166 TFEEVPYSELENGKRDVDITIIFASGFHGD-----SSPFDGEG 203


>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
          Length = 610

 Score = 75.5 bits (184), Expect = 2e-14
 Identities = 49/132 (37%), Positives = 64/132 (48%), Gaps = 6/132 (4%)

Query: 41  PLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLL 100
           P E  N F  +D    L+  Q+   LP +G LD  T   MR+PRCG  D  N     +  
Sbjct: 11  PKESCNLFVLKD---TLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNF--FPR 65

Query: 101 LGRWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHG 160
             +W K  +T+RI+     L P T   A  +AFQ WS+V PL F  +  G ADI ++F G
Sbjct: 66  KPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINF-G 124

Query: 161 RQSSYCSNTFDG 172
           R        FDG
Sbjct: 125 RWEHGDGYPFDG 136


>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
           [Homo sapiens]
          Length = 660

 Score = 75.5 bits (184), Expect = 2e-14
 Identities = 49/132 (37%), Positives = 64/132 (48%), Gaps = 6/132 (4%)

Query: 41  PLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLL 100
           P E  N F  +D    L+  Q+   LP +G LD  T   MR+PRCG  D  N     +  
Sbjct: 61  PKESCNLFVLKD---TLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNF--FPR 115

Query: 101 LGRWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHG 160
             +W K  +T+RI+     L P T   A  +AFQ WS+V PL F  +  G ADI ++F G
Sbjct: 116 KPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINF-G 174

Query: 161 RQSSYCSNTFDG 172
           R        FDG
Sbjct: 175 RWEHGDGYPFDG 186


>gi|73858572 matrix metalloproteinase 12 preproprotein [Homo
           sapiens]
          Length = 470

 Score = 73.2 bits (178), Expect = 1e-13
 Identities = 44/120 (36%), Positives = 64/120 (53%), Gaps = 3/120 (2%)

Query: 55  EALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRIL 114
           E ++  Q    L V+GQLD +T   M  PRCG+ D  + + +    +  WRK ++T+RI 
Sbjct: 62  EKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPV--WRKHYITYRIN 119

Query: 115 NLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPG 174
           N    +       A+R+AFQ WSNV PL F ++  G ADI + F  R +    + FDG G
Sbjct: 120 NYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVF-ARGAHGDFHAFDGKG 178


>gi|58331148 matrix metalloproteinase 11 preproprotein [Homo
           sapiens]
          Length = 488

 Score = 70.9 bits (172), Expect = 6e-13
 Identities = 42/101 (41%), Positives = 52/101 (51%), Gaps = 7/101 (6%)

Query: 80  MRQPRCGLEDPF------NQKTLKYLLLGRWRKKHLTFRILNLPSTLPPHTARAALRQAF 133
           +R PRCG+ DP       N++    L  GRW K  LT+RIL  P  L     R  + +A 
Sbjct: 75  LRPPRCGVPDPSDGLSARNRQKRFVLSGGRWEKTDLTYRILRFPWQLVQEQVRQTMAEAL 134

Query: 134 QDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPG 174
           + WS+V PLTF EV  G ADI + F  R        FDGPG
Sbjct: 135 KVWSDVTPLTFTEVHEGRADIMIDF-ARYWHGDDLPFDGPG 174


>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
          Length = 707

 Score = 69.7 bits (169), Expect = 1e-12
 Identities = 46/130 (35%), Positives = 66/130 (50%), Gaps = 7/130 (5%)

Query: 30  DYLSQYGYLQ-KPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLE 88
           +YL +YGY +   + G +    + +  AL   Q+   LP +G+LD AT   MR PRCG+ 
Sbjct: 47  EYLYRYGYTRVAEMRGES----KSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVP 102

Query: 89  DPFNQKTLKYLLLGRWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQ 148
           D    +T +  L  +W   ++T+ I N    LP      A  +AF  WS V PLTF  V 
Sbjct: 103 DLGRFQTFEGDL--KWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVY 160

Query: 149 AGAADIRLSF 158
           +  ADI + F
Sbjct: 161 SRDADIVIQF 170


>gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]
          Length = 467

 Score = 67.8 bits (164), Expect = 5e-12
 Identities = 46/152 (30%), Positives = 71/152 (46%), Gaps = 18/152 (11%)

Query: 30  DYLSQYGYL-QKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLE 88
           DYL ++  L     + +       I E L+  Q    L V+G+ ++ T   M++PRCG+ 
Sbjct: 35  DYLEKFYQLPSNQYQSTRKNGTNVIVEKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVP 94

Query: 89  D-------PFNQKTLKYLLLGRWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAP 141
           D       P N K         W + +LT+RI N    L       A++ AF+ WS  +P
Sbjct: 95  DSGGFMLTPGNPK---------WERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASP 145

Query: 142 LTFQEVQAGAADIRLSFHGRQSSYCSNTFDGP 173
           L F  +  G ADI ++F+ R     ++ FDGP
Sbjct: 146 LIFTRISQGEADINIAFYQRDHG-DNSPFDGP 176


>gi|73808266 matrix metalloproteinase 26 preproprotein [Homo
           sapiens]
          Length = 261

 Score = 67.8 bits (164), Expect = 5e-12
 Identities = 41/105 (39%), Positives = 56/105 (53%), Gaps = 7/105 (6%)

Query: 72  LDDATRARMRQPRCGLEDPFNQKTLKYLLLGR--WRKKHLTFRILNLPSTLPPHTARAAL 129
           LD    A + QP CG+ D  +      +  GR  W K  LT+RI+N P  + P   + ++
Sbjct: 69  LDMQMHALLHQPHCGVPDGSDTS----ISPGRCKWNKHTLTYRIINYPHDMKPSAVKDSI 124

Query: 130 RQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPG 174
             A   WSNV PL FQ+VQ G ADI++SF  + +      FDGPG
Sbjct: 125 YNAVSIWSNVTPLIFQQVQNGDADIKVSF-WQWAHEDGWPFDGPG 168


>gi|45359865 matrix metalloproteinase 20 preproprotein [Homo
           sapiens]
          Length = 483

 Score = 65.5 bits (158), Expect = 2e-11
 Identities = 40/119 (33%), Positives = 60/119 (50%), Gaps = 7/119 (5%)

Query: 57  LRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLG--RWRKKHLTFRIL 114
           ++  Q    L V+G+LD  T   +++PRCG+ D  N +    L  G  +W+K  LT+RI 
Sbjct: 72  IKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYR----LFPGEPKWKKNTLTYRIS 127

Query: 115 NLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGP 173
               ++       A+  A Q WS+  PL+F  + +G ADI +SF        S  FDGP
Sbjct: 128 KYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHG-DSYPFDGP 185


>gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]
          Length = 267

 Score = 64.3 bits (155), Expect = 6e-11
 Identities = 44/148 (29%), Positives = 71/148 (47%), Gaps = 14/148 (9%)

Query: 30  DYLSQYGYLQKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLED 89
           DYL ++       + +N+ + +     L+  Q+   LP++G L+      M++PRCG+ D
Sbjct: 37  DYLKRFYLYDSETKNANSLEAK-----LKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPD 91

Query: 90  PFNQKTLKYLLLG---RWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQE 146
                  +Y L     +W  K +T+RI++    LP  T    + +A   W    PL F++
Sbjct: 92  -----VAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRK 146

Query: 147 VQAGAADIRLSFHGRQSSYCSNTFDGPG 174
           V  G ADI + F  R +   S  FDGPG
Sbjct: 147 VVWGTADIMIGF-ARGAHGDSYPFDGPG 173


>gi|22218341 matrix metalloproteinase 21 preproprotein [Homo
           sapiens]
          Length = 569

 Score = 64.3 bits (155), Expect = 6e-11
 Identities = 59/193 (30%), Positives = 83/193 (43%), Gaps = 47/193 (24%)

Query: 31  YLSQYGYL-------QKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQP 83
           +LS+YG+          P       K   + EA+R FQ A+ LP SG+LD AT A M +P
Sbjct: 56  FLSRYGWSGVWAAWGPSPEGPPETPKGAALAEAVRRFQRANALPASGELDAATLAAMNRP 115

Query: 84  RCGLED---------------PFNQKTLKY----LLLGR--WR--------------KKH 108
           RCG+ D               P   ++ +     L L R  W+              K+ 
Sbjct: 116 RCGVPDMRPPPPSAPPSPPGPPPRARSRRSPRAPLSLSRRGWQPRGYPDGGAAQAFSKRT 175

Query: 109 LTFRILN--LPSTLPPHTARAALRQAFQDWSNVAPLTFQE---VQAGAADIRLSFHGRQS 163
           L++R+L   L S L     R  +  AF+ WS V PL F+E       A DI+L F   + 
Sbjct: 176 LSWRLLGEALSSQLSVADQRRIVALAFRMWSEVTPLDFREDLAAPGAAVDIKLGFGRGRH 235

Query: 164 SYCSNTFDGPGRQ 176
             C   FDG G++
Sbjct: 236 LGCPRAFDGSGQE 248


>gi|73808271 matrix metalloproteinase 28 isoform 3 [Homo sapiens]
          Length = 130

 Score = 50.8 bits (120), Expect = 6e-07
 Identities = 26/59 (44%), Positives = 38/59 (64%), Gaps = 2/59 (3%)

Query: 31 YLSQYGYLQKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLED 89
          +L +YGYL + +  +        ++A+RAFQ  S+LPVSG LD AT  +M +PRCG+ D
Sbjct: 39 FLEKYGYLNEQVPKAPT--STRFSDAIRAFQWVSQLPVSGVLDRATLRQMTRPRCGVTD 95


>gi|5902004 matrix metalloproteinase 23B precursor [Homo sapiens]
          Length = 390

 Score = 50.8 bits (120), Expect = 6e-07
 Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 7/78 (8%)

Query: 103 RWRKKHLTFRILNLP-STLPPHTARAALRQAFQDWSNVAPLTFQEV-QAGAADIRLSFHG 160
           RW   +LT+RIL+ P + L P   R AL  AF+ WS+V+P +F+EV     +D+R+ F+ 
Sbjct: 87  RWDHFNLTYRILSFPRNLLSPRETRRALAAAFRMWSDVSPFSFREVAPEQPSDLRIGFYP 146

Query: 161 RQSSYC-----SNTFDGP 173
              + C      + FDGP
Sbjct: 147 INHTDCLVSALHHCFDGP 164


>gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 358

 Score = 30.0 bits (66), Expect = 1.2
 Identities = 17/44 (38%), Positives = 20/44 (45%)

Query: 115 NLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSF 158
           N    LP      A  +AF+ WSN + LTF        DI LSF
Sbjct: 188 NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSF 231


>gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 198

 Score = 30.0 bits (66), Expect = 1.2
 Identities = 17/44 (38%), Positives = 20/44 (45%)

Query: 115 NLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSF 158
           N    LP      A  +AF+ WSN + LTF        DI LSF
Sbjct: 28  NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSF 71


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,452,461
Number of Sequences: 37866
Number of extensions: 305214
Number of successful extensions: 674
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 613
Number of HSP's gapped (non-prelim): 38
length of query: 183
length of database: 18,247,518
effective HSP length: 96
effective length of query: 87
effective length of database: 14,612,382
effective search space: 1271277234
effective search space used: 1271277234
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.