Guide to the Human Genome
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Search of human proteins with 239749546

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239749546 PREDICTED: similar to solute carrier family 4
(anion exchanger), member 1, adaptor protein [Homo sapiens]
         (210 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239755020 PREDICTED: similar to solute carrier family 4 (anio...   436   e-123
gi|239749546 PREDICTED: similar to solute carrier family 4 (anio...   436   e-123
gi|239743698 PREDICTED: hypothetical protein XP_002342928 [Homo ...   436   e-123
gi|155722990 solute carrier family 4 (anion exchanger), member 1...   289   1e-78
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    53   2e-07
gi|17975763 myelin transcription factor 1 [Homo sapiens]               47   1e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    47   2e-05
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap...    47   2e-05
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    46   2e-05
gi|166795264 AE binding protein 2 isoform b [Homo sapiens]             46   3e-05
gi|166795262 AE binding protein 2 isoform a [Homo sapiens]             46   3e-05
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H...    45   4e-05
gi|221219020 NYD-SP11 protein [Homo sapiens]                           45   4e-05
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    45   4e-05
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    45   6e-05
gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sa...    45   6e-05
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ...    44   8e-05
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap...    44   8e-05
gi|7657465 podocalyxin-like 2 [Homo sapiens]                           44   8e-05
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        44   1e-04
gi|150170670 piccolo isoform 2 [Homo sapiens]                          44   1e-04
gi|150378539 piccolo isoform 1 [Homo sapiens]                          44   1e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       44   1e-04
gi|87298939 hypothetical protein LOC131831 [Homo sapiens]              43   2e-04
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    43   2e-04
gi|215422388 death-domain associated protein isoform a [Homo sap...    43   2e-04
gi|215422366 death-domain associated protein isoform b [Homo sap...    43   2e-04
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]              42   3e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    42   3e-04
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]            42   4e-04

>gi|239755020 PREDICTED: similar to solute carrier family 4 (anion
           exchanger), member 1, adaptor protein [Homo sapiens]
          Length = 210

 Score =  436 bits (1121), Expect = e-123
 Identities = 210/210 (100%), Positives = 210/210 (100%)

Query: 1   MKGGSKFKLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 60
           MKGGSKFKLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE
Sbjct: 1   MKGGSKFKLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 60

Query: 61  DGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLC 120
           DGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLC
Sbjct: 61  DGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLC 120

Query: 121 AGPSASKNEYEKSRGELKKKKTPGPANFHQHFLPNILKMTQTTVCGSHLKVKVEMAEPIL 180
           AGPSASKNEYEKSRGELKKKKTPGPANFHQHFLPNILKMTQTTVCGSHLKVKVEMAEPIL
Sbjct: 121 AGPSASKNEYEKSRGELKKKKTPGPANFHQHFLPNILKMTQTTVCGSHLKVKVEMAEPIL 180

Query: 181 MTSMAIDCFRIPKENLVDHVTWNIWDNVSN 210
           MTSMAIDCFRIPKENLVDHVTWNIWDNVSN
Sbjct: 181 MTSMAIDCFRIPKENLVDHVTWNIWDNVSN 210


>gi|239749546 PREDICTED: similar to solute carrier family 4 (anion
           exchanger), member 1, adaptor protein [Homo sapiens]
          Length = 210

 Score =  436 bits (1121), Expect = e-123
 Identities = 210/210 (100%), Positives = 210/210 (100%)

Query: 1   MKGGSKFKLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 60
           MKGGSKFKLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE
Sbjct: 1   MKGGSKFKLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 60

Query: 61  DGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLC 120
           DGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLC
Sbjct: 61  DGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLC 120

Query: 121 AGPSASKNEYEKSRGELKKKKTPGPANFHQHFLPNILKMTQTTVCGSHLKVKVEMAEPIL 180
           AGPSASKNEYEKSRGELKKKKTPGPANFHQHFLPNILKMTQTTVCGSHLKVKVEMAEPIL
Sbjct: 121 AGPSASKNEYEKSRGELKKKKTPGPANFHQHFLPNILKMTQTTVCGSHLKVKVEMAEPIL 180

Query: 181 MTSMAIDCFRIPKENLVDHVTWNIWDNVSN 210
           MTSMAIDCFRIPKENLVDHVTWNIWDNVSN
Sbjct: 181 MTSMAIDCFRIPKENLVDHVTWNIWDNVSN 210


>gi|239743698 PREDICTED: hypothetical protein XP_002342928 [Homo
           sapiens]
          Length = 210

 Score =  436 bits (1121), Expect = e-123
 Identities = 210/210 (100%), Positives = 210/210 (100%)

Query: 1   MKGGSKFKLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 60
           MKGGSKFKLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE
Sbjct: 1   MKGGSKFKLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 60

Query: 61  DGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLC 120
           DGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLC
Sbjct: 61  DGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLC 120

Query: 121 AGPSASKNEYEKSRGELKKKKTPGPANFHQHFLPNILKMTQTTVCGSHLKVKVEMAEPIL 180
           AGPSASKNEYEKSRGELKKKKTPGPANFHQHFLPNILKMTQTTVCGSHLKVKVEMAEPIL
Sbjct: 121 AGPSASKNEYEKSRGELKKKKTPGPANFHQHFLPNILKMTQTTVCGSHLKVKVEMAEPIL 180

Query: 181 MTSMAIDCFRIPKENLVDHVTWNIWDNVSN 210
           MTSMAIDCFRIPKENLVDHVTWNIWDNVSN
Sbjct: 181 MTSMAIDCFRIPKENLVDHVTWNIWDNVSN 210


>gi|155722990 solute carrier family 4 (anion exchanger), member 1,
           adaptor protein [Homo sapiens]
          Length = 796

 Score =  289 bits (739), Expect = 1e-78
 Identities = 140/145 (96%), Positives = 141/145 (97%)

Query: 1   MKGGSKFKLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 60
           MKGGSKFKLKT T GKLPPK PELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE
Sbjct: 611 MKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLE 670

Query: 61  DGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLC 120
           DGSLSRPQPEI+PEAAVQEMRPPTDLTHFKE QTHENMSQLSEEEQNKDYQDCSKTTSLC
Sbjct: 671 DGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLC 730

Query: 121 AGPSASKNEYEKSRGELKKKKTPGP 145
           AGPSASKNEYEKSRGELKKKKTPGP
Sbjct: 731 AGPSASKNEYEKSRGELKKKKTPGP 755



 Score = 29.6 bits (65), Expect = 1.9
 Identities = 30/126 (23%), Positives = 48/126 (38%), Gaps = 10/126 (7%)

Query: 28  LMRMKDEPEVEEEEEEEEE--------EEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQE 79
           L RMK   +++E+ E  E         E +  E  E+ K     LS    +   +A + E
Sbjct: 483 LNRMKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESPSQDSLDAFMSE 542

Query: 80  MRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKK 139
           M+  + L      + H    +L +E+Q    +   K       P   K E + +  E K 
Sbjct: 543 MKSGSTLDGVSRKKLHLRTFELRKEQQR--LKGLIKIVKPAEIPELKKTETQTTGAENKA 600

Query: 140 KKTPGP 145
           KK   P
Sbjct: 601 KKLTLP 606


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 37/137 (27%), Positives = 65/137 (47%), Gaps = 14/137 (10%)

Query: 23  ELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQ---------P 73
           E P   +R++ +  ++ EEEEEEEEE+E+++ E++  ++G  SR  P ++         P
Sbjct: 253 ETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIP 312

Query: 74  EAAVQEMRPPTDLTHFKENQTHENMSQL--SEEEQNKDY---QDCSKTTSLCAGPSASKN 128
               +EM      T  +E +  E   +   S+EE  K +   Q   K     +     + 
Sbjct: 313 RVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEER 372

Query: 129 EYEKSRGELKKKKTPGP 145
           E + S+G  +K K+P P
Sbjct: 373 EIKSSQGLKEKSKSPSP 389



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 12/29 (41%), Positives = 20/29 (68%)

Query: 32   KDEPEVEEEEEEEEEEEKEKEEHEKKKLE 60
            +++   E+EEEE++E EKE E    ++LE
Sbjct: 1248 REKRRKEQEEEEQKEREKEAERERNRQLE 1276



 Score = 30.0 bits (66), Expect = 1.5
 Identities = 20/107 (18%), Positives = 42/107 (39%), Gaps = 18/107 (16%)

Query: 21  HPE-----LPPTLMRMKDEPEVE-------------EEEEEEEEEEKEKEEHEKKKLEDG 62
           HPE     LPP      + PE+E             EE+ + ++E+  K E    ++   
Sbjct: 175 HPEGVASLLPPDFQSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQA 234

Query: 63  SLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKD 109
             ++     QP    ++   P+     + ++  +   +  EEE+ ++
Sbjct: 235 RAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEE 281



 Score = 28.9 bits (63), Expect = 3.3
 Identities = 11/28 (39%), Positives = 20/28 (71%)

Query: 30   RMKDEPEVEEEEEEEEEEEKEKEEHEKK 57
            R K+  +  +E+EEEE++E+EKE   ++
Sbjct: 1244 RAKEREKRRKEQEEEEQKEREKEAERER 1271



 Score = 28.9 bits (63), Expect = 3.3
 Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 3/40 (7%)

Query: 30   RMKDEPEVEEEEEEEEEEEKEKEEH---EKKKLEDGSLSR 66
            R K   E EEEE++E E+E E+E +   E++K  + S  R
Sbjct: 1248 REKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRER 1287



 Score = 28.5 bits (62), Expect = 4.3
 Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 7/57 (12%)

Query: 10   KTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEE------EEEKEKEEHEKKKLE 60
            KT   G   P HP  PP + +    P  E+ E+E        E E+E E  E+ + E
Sbjct: 1107 KTEEQGIPRPLHPPPPPPV-QPPQHPRAEQREQERAVREQWAEREREMERRERTRSE 1162



 Score = 27.7 bits (60), Expect = 7.4
 Identities = 18/69 (26%), Positives = 30/69 (43%), Gaps = 14/69 (20%)

Query: 38  EEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHEN 97
           E  + EEEEEEKE E               +P + P+ +V+   PP      K+    + 
Sbjct: 931 ENGQREEEEEEKEPE--------------AEPPVPPQVSVEVALPPPAEHEVKKVTLGDT 976

Query: 98  MSQLSEEEQ 106
           +++ S  +Q
Sbjct: 977 LTRRSISQQ 985



 Score = 27.7 bits (60), Expect = 7.4
 Identities = 18/89 (20%), Positives = 38/89 (42%)

Query: 30   RMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTHF 89
            R +   E E+  +E+EEEE+++ E E ++  +  L R +         +E     +    
Sbjct: 1241 RAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRG 1300

Query: 90   KENQTHENMSQLSEEEQNKDYQDCSKTTS 118
              ++  E   +   E   +D +  S++ S
Sbjct: 1301 DRDRDRERDRERGRERDRRDTKRHSRSRS 1329



 Score = 27.3 bits (59), Expect = 9.6
 Identities = 15/51 (29%), Positives = 22/51 (43%), Gaps = 2/51 (3%)

Query: 18   PPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHE--KKKLEDGSLSR 66
            PP+HP             +  E E E E  E+ + E E  + K+ +G  SR
Sbjct: 1127 PPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSR 1177


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 25/76 (32%), Positives = 45/76 (59%), Gaps = 2/76 (2%)

Query: 28  LMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLT 87
           ++  ++E E EEEEEEEEEE++E+EE E+++ E+      + E + E   +E   P  + 
Sbjct: 254 ILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI- 312

Query: 88  HFKENQTHENMSQLSE 103
            F+E+ +H +  +  E
Sbjct: 313 -FQEDTSHTSAQKAPE 327



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 32/91 (35%), Positives = 48/91 (52%), Gaps = 17/91 (18%)

Query: 32  KDEPEVEEEEEEEEEEEKEKEEHEKKKL--EDGSLSRPQ----------PEIQPE-AAVQ 78
           ++E E EEEEEEEEEEE+E+EE     +  ED S +  Q          P  +PE + + 
Sbjct: 285 EEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIV 344

Query: 79  EMRPPTDLTHFKENQTHENMSQLSEEEQNKD 109
           E+R   D    K+  TH   S +++E + +D
Sbjct: 345 EVRSDDD----KDEDTHSRKSTVTDESEMQD 371



 Score = 34.7 bits (78), Expect = 0.060
 Identities = 21/72 (29%), Positives = 37/72 (51%)

Query: 8   KLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRP 67
           ++ T  +  L P+  E   +    K +  +  EEE+EEEEE+E+EE E ++ E+      
Sbjct: 226 EVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEE 285

Query: 68  QPEIQPEAAVQE 79
           + E + E   +E
Sbjct: 286 EEEEEEEEEEEE 297


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 19/135 (14%)

Query: 11  TRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPE 70
           T   G  P    +L    +   DE E EEEEEEEEEEE+E+EE + ++ E+      + E
Sbjct: 865 TPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEE 924

Query: 71  IQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEY 130
            + E   +E             +  E   +L EEE+ +D ++  +   +         E+
Sbjct: 925 EEEEEEFEE-------------EFEEEEGELEEEEEEEDEEEEEELEEV------EDLEF 965

Query: 131 EKSRGELKKKKTPGP 145
             + GE+++   P P
Sbjct: 966 GTAGGEVEEGAPPPP 980



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 7/108 (6%)

Query: 34   EPEVEEEE---EEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQ----PEAAVQEMRPPTDL 86
            E E EEEE   EEEEEEE E+EE E +++ED        E++    P   +    PP + 
Sbjct: 932  EEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPES 991

Query: 87   THFKENQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSR 134
                + +       L E E+    ++    T+    P A  ++ E  R
Sbjct: 992  PPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVER 1039



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 32/124 (25%), Positives = 47/124 (37%), Gaps = 28/124 (22%)

Query: 18   PPK---HPELPPTLMRMKDEPEVEEEE-----------------EEEEEEEKEKEEHEKK 57
            PPK    PE  P L+   +EP  EEE                  E E E E        +
Sbjct: 992  PPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQ 1051

Query: 58   KLEDGSLSRPQP--EIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQN------KD 109
            +L +   S P    E + E    +++PP +    +E +T      L E+EQ+       D
Sbjct: 1052 ELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLAD 1111

Query: 110  YQDC 113
            + DC
Sbjct: 1112 FIDC 1115



 Score = 30.0 bits (66), Expect = 1.5
 Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 7/53 (13%)

Query: 16   KLPPKHPELPPTLMRMKDE-------PEVEEEEEEEEEEEKEKEEHEKKKLED 61
            +L  + P  PPTL+  + E       P  E   EEE E E E E  ++K+ +D
Sbjct: 1052 ELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104


>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
           sapiens]
          Length = 525

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 1/95 (1%)

Query: 19  PKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQ 78
           P  P+L          P    EEEEEEEEE+E+E  E+++ ED  +   QP+    A   
Sbjct: 292 PSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEED 351

Query: 79  EMRPPTDLTHFKENQTHENMSQLSEEEQN-KDYQD 112
           +M P  + T    +   E  ++  E E++ KD ++
Sbjct: 352 KMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEE 386


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 23/51 (45%), Positives = 34/51 (66%)

Query: 32   KDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRP 82
            +DE E EEEEEEEE+EE+E+EE E+++ E+   S P+       A++  RP
Sbjct: 1076 EDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRP 1126



 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 8/98 (8%)

Query: 19   PKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQ 78
            P  P   P      D  + EEEEEEEEEEE+E+EE E ++ E G       E  P+ A  
Sbjct: 1332 PVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGG----NVEKDPDGAKS 1387

Query: 79   EMRPPTDLTHFKENQT----HENMSQLSEEEQNKDYQD 112
            + +   +++  KE+      HE   +  EE  + +  D
Sbjct: 1388 QEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHD 1425



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 36/106 (33%), Positives = 52/106 (49%), Gaps = 9/106 (8%)

Query: 18   PPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEK-----KKLEDGSLSRPQPEIQ 72
            P   P   P    +K E E EEEEEEEEEEE+E+ E E+     +K  DG+ S+ + E  
Sbjct: 1335 PNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEE-- 1392

Query: 73   PEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTS 118
            PE + ++        H +E +  E  S    E+ + D +D S   S
Sbjct: 1393 PEISTEKEDSARLDDHEEEEEEDEEPSH--NEDHDADDEDDSHMES 1436



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 4/55 (7%)

Query: 28   LMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRP 82
            L+ +  E   EEEEEE+EEEE+E+EE E    ED      + E + E  +Q   P
Sbjct: 1061 LLELSKESSEEEEEEEDEEEEEEEEEEE----EDEEEEEEEEEEEEEENIQSSPP 1111



 Score = 34.7 bits (78), Expect = 0.060
 Identities = 17/46 (36%), Positives = 26/46 (56%)

Query: 38   EEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPP 83
            +E  EEEEEEE E+EE E+++ E+      + E + E    +  PP
Sbjct: 1066 KESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPP 1111



 Score = 34.3 bits (77), Expect = 0.079
 Identities = 20/66 (30%), Positives = 31/66 (46%)

Query: 22   PELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMR 81
            PE  P         E+ +E  EEEEEE+++EE E+++ E+      + E + E       
Sbjct: 1049 PESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQS 1108

Query: 82   PPTDLT 87
             P  LT
Sbjct: 1109 SPPRLT 1114



 Score = 30.8 bits (68), Expect = 0.87
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 12/51 (23%)

Query: 32   KDEPEVE------------EEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPE 70
            K+EPE+             EEEEEE+EE    E+H+    +D  +   + E
Sbjct: 1390 KEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE 1440



 Score = 29.6 bits (65), Expect = 1.9
 Identities = 22/91 (24%), Positives = 41/91 (45%), Gaps = 20/91 (21%)

Query: 34   EPEVEEEEEEEEE--EEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTHFKE 91
            +PE   E +EE    E+ +K++ +  K  D       P      A  E+          +
Sbjct: 1495 DPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNP------ATMEI----------D 1538

Query: 92   NQTHENMSQLSEE--EQNKDYQDCSKTTSLC 120
            ++T + +  L++E  EQ+  +QDC++T   C
Sbjct: 1539 SETVQAVQSLTQESSEQDDTFQDCAETQEAC 1569



 Score = 28.5 bits (62), Expect = 4.3
 Identities = 33/143 (23%), Positives = 56/143 (39%), Gaps = 20/143 (13%)

Query: 7    FKLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEH---EKKKLEDGS 63
            FKL   T    PP+ P        M+ + +V  EE++E  E K        E++  E G 
Sbjct: 1269 FKLNLYT----PPETP--------MEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGE 1316

Query: 64   LSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLCAGP 123
               PQ E + E     + P T      E+   +   +  EEE+ ++ ++  +      G 
Sbjct: 1317 ALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGG 1376

Query: 124  SASKN-----EYEKSRGELKKKK 141
            +  K+       EK   E+  +K
Sbjct: 1377 NVEKDPDGAKSQEKEEPEISTEK 1399


>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
          Length = 517

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 43/153 (28%), Positives = 60/153 (39%), Gaps = 29/153 (18%)

Query: 16  KLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGS------------ 63
           +L P  P  P +  R + EP  EEEEEEEEEEE E E      L  GS            
Sbjct: 16  RLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVG 75

Query: 64  ------LSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDY------- 110
                 +S P PE   +A   E     D    +E +   + S   EEE + +        
Sbjct: 76  GGEAETMSEPSPESASQAGEDEDEEEDD----EEEEDESSSSGGGEEESSAESLVGSSGG 131

Query: 111 QDCSKTTSLCAGPSASKNEYEKSRGELKKKKTP 143
               +T SL  G ++S +     +  L++ K P
Sbjct: 132 SSSDETRSLSPGAASSSSGDGDGKEGLEEPKGP 164


>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
          Length = 503

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 43/153 (28%), Positives = 60/153 (39%), Gaps = 29/153 (18%)

Query: 16  KLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGS------------ 63
           +L P  P  P +  R + EP  EEEEEEEEEEE E E      L  GS            
Sbjct: 16  RLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVG 75

Query: 64  ------LSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDY------- 110
                 +S P PE   +A   E     D    +E +   + S   EEE + +        
Sbjct: 76  GGEAETMSEPSPESASQAGEDEDEEEDD----EEEEDESSSSGGGEEESSAESLVGSSGG 131

Query: 111 QDCSKTTSLCAGPSASKNEYEKSRGELKKKKTP 143
               +T SL  G ++S +     +  L++ K P
Sbjct: 132 SSSDETRSLSPGAASSSSGDGDGKEGLEEPKGP 164


>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
           sapiens]
          Length = 1251

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 36/110 (32%), Positives = 54/110 (49%), Gaps = 24/110 (21%)

Query: 23  ELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHE-------------KKKLEDGSLSRPQP 69
           ++P  L R+++E E EEEEEEEEEEE+E+E  E              +  EDG  +RPQ 
Sbjct: 342 KMPRELSRIEEEKEDEEEEEEEEEEEEEEEVTEVLLDSCVVSQVGVGQSEEDG--TRPQS 399

Query: 70  EIQP---EAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKT 116
                  E   +E +         E +  E   +++EEE  K+ QD ++T
Sbjct: 400 TSDQKLWEEVGEEAKKEA------EEKAKEEAEEVAEEEAEKEPQDWAET 443



 Score = 34.7 bits (78), Expect = 0.060
 Identities = 16/44 (36%), Positives = 29/44 (65%)

Query: 33  DEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAA 76
           +E + E EE+ +EE E+  EE  +K+ +D + ++ +PE + EAA
Sbjct: 411 EEAKKEAEEKAKEEAEEVAEEEAEKEPQDWAETKEEPEAEAEAA 454



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 2/53 (3%)

Query: 25 PPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAV 77
          P   M  + EPE   EE E E E    EE  K+  E+ +++ P P+   EAA+
Sbjct: 29 PEPEMEAEVEPEPNPEEAETESESMPPEESFKE--EEVAVADPSPQETKEAAL 79



 Score = 28.1 bits (61), Expect = 5.6
 Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 2/52 (3%)

Query: 30  RMKDEPE--VEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQE 79
           + K+E E   EEE E+E ++  E +E  + + E  S   P  +  PE  V++
Sbjct: 420 KAKEEAEEVAEEEAEKEPQDWAETKEEPEAEAEAASSGVPATKQHPEVQVED 471


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 5/111 (4%)

Query: 31   MKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTHFK 90
            +  E E E EEEEE EEE+ +EE E++K E+    +   + + E   ++     +    K
Sbjct: 2243 LSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEK 2302

Query: 91   ENQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKK 141
            E +  E   ++  EE+ +   D  +    C    + + E ++ +  LKK+K
Sbjct: 2303 E-EVFEEKEEIMSEEETESLSDEEEEEESC----SLEEEVDREKEILKKEK 2348



 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 34/116 (29%), Positives = 56/116 (48%), Gaps = 15/116 (12%)

Query: 29   MRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTH 88
            +R ++E   EEEE EE++ EKE+EE +KKK E     + + E+Q +  V E +       
Sbjct: 2262 VREEEEERKEEEEGEEKQVEKEEEEKKKKKKE-----KKKEEVQEKEEVFEEK------- 2309

Query: 89   FKENQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKKTPG 144
             +E  + E    LS+EE+ +  + CS    +       K E +    E ++K   G
Sbjct: 2310 -EEIMSEEETESLSDEEEEE--ESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRG 2362



 Score = 31.6 bits (70), Expect = 0.51
 Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 28/106 (26%)

Query: 36   EVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTH 95
            EVE EE   EE E   +E EK++    SLS  + E + E   +E           E +  
Sbjct: 2219 EVESEEHFSEEMESLLDELEKQE----SLSSEEEEEREEEEERE-----------EEEVR 2263

Query: 96   ENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKK 141
            E   +  EEE+ ++ Q               K E EK + + +KKK
Sbjct: 2264 EEEEERKEEEEGEEKQ-------------VEKEEEEKKKKKKEKKK 2296



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 30/117 (25%), Positives = 53/117 (45%), Gaps = 18/117 (15%)

Query: 32   KDEPEVEEEE------EEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTD 85
            KDE EV  EE      EE+E++  E++ H +++ +   + R +   + + A +E +   +
Sbjct: 1539 KDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQE 1598

Query: 86   LTHFKENQTHENMSQLSEEEQN------KDYQDCSKTTSLCAGPSASKNEYEKSRGE 136
                 E +  +   QL++EE+       K  QD  +  +   G  A K E    RGE
Sbjct: 1599 -----EEKLAQEERQLAQEERKLAQAYVKITQD-DREMAQAEGKFAQKEETLAQRGE 1649


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 28/115 (24%), Positives = 53/115 (46%), Gaps = 2/115 (1%)

Query: 30  RMKDEPEVEEEEEEEEEEEKE--KEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLT 87
           + K+  E EE EE EEEEEKE  ++E  K+K ++    +   E +     +E        
Sbjct: 6   KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65

Query: 88  HFKENQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKKT 142
             K+ +  E   +  EEE+ K+ ++  +           + E E+ + + +++KT
Sbjct: 66  RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120



 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 24/51 (47%), Positives = 30/51 (58%)

Query: 8  KLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKK 58
          K KT+   K   K  E      + K + E EE EEEEEEEE+EKEE EK++
Sbjct: 43 KKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEE 93



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 16/113 (14%)

Query: 30  RMKDEPEVEEEEEEEE-EEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTH 88
           + K + E EE EE EE EEE+EKE   K+K ++    R + E + +    E R   +   
Sbjct: 3   KKKKKKETEETEETEETEEEEEKEGKRKEKRKE---KRKEKEKKKKTKETEKRKEKEEEE 59

Query: 89  FKENQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKK 141
            K  +  +   +  E E+ ++ ++              K E EK  G  +KKK
Sbjct: 60  KKRKRKRKKKKEEEEREEEEEEEE------------EEKEEEEKEEGRRRKKK 100



 Score = 36.6 bits (83), Expect = 0.016
 Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 8/102 (7%)

Query: 15  GKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPE 74
           GK   K  E      + K   E E+ +E+EEEE+K K + +KKK E+    R + E + E
Sbjct: 27  GKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEE---EREEEEEEEE 83

Query: 75  AAVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKT 116
              +E          K+ +         EEE+ K  +   KT
Sbjct: 84  EEKEEEEKEEGRRRKKKKKRRR-----KEEEEEKKKKRRRKT 120



 Score = 29.6 bits (65), Expect = 1.9
 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 11/63 (17%)

Query: 10 KTRTAGKLPPKHPELPPTLMRMKDEPEVEEEE-----------EEEEEEEKEKEEHEKKK 58
          K +   K   K  E        +   E EEEE           EEEE EE+E+EE E+K+
Sbjct: 28 KRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKE 87

Query: 59 LED 61
           E+
Sbjct: 88 EEE 90


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 21/46 (45%), Positives = 33/46 (71%)

Query: 32  KDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAV 77
           ++E + EEEEEEE+EEE+E+EE E++K  +  LS   PE + + A+
Sbjct: 865 EEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQAI 910



 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 18/37 (48%), Positives = 27/37 (72%)

Query: 33  DEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQP 69
           +E E EEEE+EEEEEE+E+EE E+++ E+      +P
Sbjct: 860 EEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEP 896



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 16/29 (55%), Positives = 24/29 (82%)

Query: 33  DEPEVEEEEEEEEEEEKEKEEHEKKKLED 61
           D  E EEEEEE+EEEE+E+E+ E+++ E+
Sbjct: 858 DSEEEEEEEEEQEEEEEEEEQEEEEEEEE 886



 Score = 36.6 bits (83), Expect = 0.016
 Identities = 16/29 (55%), Positives = 24/29 (82%)

Query: 33  DEPEVEEEEEEEEEEEKEKEEHEKKKLED 61
           D  + EEEEEEEEE+E+E+EE E+++ E+
Sbjct: 855 DGGDSEEEEEEEEEQEEEEEEEEQEEEEE 883



 Score = 27.3 bits (59), Expect = 9.6
 Identities = 12/38 (31%), Positives = 23/38 (60%)

Query: 42  EEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQE 79
           + EEEEE+E+E+ E+++ E+      + E + E   +E
Sbjct: 858 DSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895


>gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo
            sapiens]
          Length = 1925

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 7/118 (5%)

Query: 33   DEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTHFKEN 92
            +E E E EEEEEEEEE E+EE  K+++E+    R + E +   A     P  +     + 
Sbjct: 1769 EEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQW 1828

Query: 93   QTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNE-------YEKSRGELKKKKTP 143
            Q  + ++ + +EEQ +D ++  +     A    +  E        E SRGE+     P
Sbjct: 1829 QWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEALLENMIQNILVEASRGEVVLTSRP 1886


>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
           isoform 1 [Homo sapiens]
          Length = 1112

 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 34/128 (26%), Positives = 61/128 (47%), Gaps = 14/128 (10%)

Query: 20  KHPELP-PTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSL---SRPQPEIQPEA 75
           K PE   P + +   +P+ +E++ +E+E +KEK++ ++KK ED      + P P   P  
Sbjct: 737 KSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKAEDLDFWLSTTPPPAPAPAP 796

Query: 76  AVQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRG 135
           A     P TD       +  +  ++   EE + + QD  K +         K + E+++G
Sbjct: 797 APV---PSTD-------ECEDAKTEAQGEEDDAEGQDQDKKSPKPKKKKHRKEKEERTKG 846

Query: 136 ELKKKKTP 143
           + K KK P
Sbjct: 847 KKKSKKQP 854



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 15/52 (28%), Positives = 27/52 (51%)

Query: 32  KDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPP 83
           K  P+ ++++  +E+EE+ K + + KK   GS       +Q  A  +E  PP
Sbjct: 826 KKSPKPKKKKHRKEKEERTKGKKKSKKQPPGSEEAAGEPVQNGAPEEEQLPP 877



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 9/96 (9%)

Query: 17  LPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAA 76
           +P K P LP     M D+  V+ EEE    ++ EK++  KK+ E     + +    P  +
Sbjct: 620 VPLKVPGLP-----MSDQ-YVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTES 673

Query: 77  VQEMRPPTDLTHFKENQTHENMSQLSEEEQNKDYQD 112
            +++ P   +    E       + L  +E +KD  D
Sbjct: 674 DEDIAPAQQVDIVTEEMPE---NALPSDEDDKDPND 706



 Score = 27.3 bits (59), Expect = 9.6
 Identities = 13/40 (32%), Positives = 21/40 (52%)

Query: 18  PPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKK 57
           PP  P   P  +   DE E  + E + EE++ E ++ +KK
Sbjct: 788 PPPAPAPAPAPVPSTDECEDAKTEAQGEEDDAEGQDQDKK 827


>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
           sapiens]
          Length = 528

 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 36/107 (33%), Positives = 52/107 (48%), Gaps = 9/107 (8%)

Query: 9   LKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDG--SLSR 66
           L   +A  L     E PP    +   P  EEEEEEEEEEE+ +EE E++  E+    LS 
Sbjct: 289 LPAPSAPDLTEPKEEQPP----VPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSP 344

Query: 67  PQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQLSEEEQN-KDYQD 112
           PQP    E    +M P  + T    +   E  ++  E E++ KD ++
Sbjct: 345 PQPASPAEE--DKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEE 389


>gi|7657465 podocalyxin-like 2 [Homo sapiens]
          Length = 605

 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 29/63 (46%), Positives = 34/63 (53%), Gaps = 6/63 (9%)

Query: 22  PELPPTLMRMK------DEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEA 75
           P LP  L +M         P  EEEEEEEEEEE+EKEE EK++ E+     P    Q EA
Sbjct: 140 PNLPSPLPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEA 199

Query: 76  AVQ 78
             Q
Sbjct: 200 KPQ 202



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 3/70 (4%)

Query: 17  LPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKK---LEDGSLSRPQPEIQP 73
           LP  +   PP  M  ++E E EEEEEE E+EE EK+E E+++     +GS    +P+++ 
Sbjct: 146 LPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRD 205

Query: 74  EAAVQEMRPP 83
            +     + P
Sbjct: 206 FSLTSSSQTP 215


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 35/129 (27%), Positives = 59/129 (45%), Gaps = 8/129 (6%)

Query: 19  PKHPELP--PTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAA 76
           P+ P  P  P     ++E E EE+EEEEEE+E+E+EE E+++ E+      + E     A
Sbjct: 718 PQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVA 777

Query: 77  VQEMRPPTDLTHFKENQTHENMSQ------LSEEEQNKDYQDCSKTTSLCAGPSASKNEY 130
           + E+  P   +  + ++   + SQ      L  ++Q +     S           SK   
Sbjct: 778 LGEVLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLV 837

Query: 131 EKSRGELKK 139
             S G++KK
Sbjct: 838 LVSPGDMKK 846


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 30/107 (28%), Positives = 56/107 (52%), Gaps = 7/107 (6%)

Query: 2    KGGSKFKLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKE-EHEKKKLE 60
            KG SK + K R        H  L PT+    +E E+ EEEE  +E+EK++E E +++K  
Sbjct: 1749 KGESKQQRKARHR-----PHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSS 1803

Query: 61   DGSLSRPQPEIQPEAAVQEMR-PPTDLTHFKENQTHENMSQLSEEEQ 106
                 + + E++ +   +  + PP++L+  ++    E + Q +E E+
Sbjct: 1804 SKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEE 1850



 Score = 31.2 bits (69), Expect = 0.67
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 1/63 (1%)

Query: 8    KLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRP 67
            KL+   A  L  K P LP     + +E ++  EE++   EEK+    +KK L +   S P
Sbjct: 1199 KLEKDKASALQEKKP-LPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAP 1257

Query: 68   QPE 70
            + +
Sbjct: 1258 EEQ 1260



 Score = 27.7 bits (60), Expect = 7.4
 Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 23/126 (18%)

Query: 31   MKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTHFK 90
            ++++  + EE++   EEEK + E +K  LE+   +    ++ PEA           T   
Sbjct: 1208 LQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAK----------TSAP 1257

Query: 91   ENQTHE---NMSQLSEEE---------QNKDYQDCSKTTSLCAG-PSASKNEYEKSRGEL 137
            E Q H+   +  Q++EE+           +  Q  +K   L +G P +   E +K+   +
Sbjct: 1258 EEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTI 1317

Query: 138  KKKKTP 143
            K++  P
Sbjct: 1318 KEQPQP 1323


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 30/107 (28%), Positives = 56/107 (52%), Gaps = 7/107 (6%)

Query: 2    KGGSKFKLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKE-EHEKKKLE 60
            KG SK + K R        H  L PT+    +E E+ EEEE  +E+EK++E E +++K  
Sbjct: 1749 KGESKQQRKARHR-----PHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSS 1803

Query: 61   DGSLSRPQPEIQPEAAVQEMR-PPTDLTHFKENQTHENMSQLSEEEQ 106
                 + + E++ +   +  + PP++L+  ++    E + Q +E E+
Sbjct: 1804 SKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEE 1850



 Score = 31.2 bits (69), Expect = 0.67
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 1/63 (1%)

Query: 8    KLKTRTAGKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRP 67
            KL+   A  L  K P LP     + +E ++  EE++   EEK+    +KK L +   S P
Sbjct: 1199 KLEKDKASALQEKKP-LPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAP 1257

Query: 68   QPE 70
            + +
Sbjct: 1258 EEQ 1260



 Score = 27.7 bits (60), Expect = 7.4
 Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 23/126 (18%)

Query: 31   MKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTHFK 90
            ++++  + EE++   EEEK + E +K  LE+   +    ++ PEA           T   
Sbjct: 1208 LQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAK----------TSAP 1257

Query: 91   ENQTHE---NMSQLSEEE---------QNKDYQDCSKTTSLCAG-PSASKNEYEKSRGEL 137
            E Q H+   +  Q++EE+           +  Q  +K   L +G P +   E +K+   +
Sbjct: 1258 EEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTI 1317

Query: 138  KKKKTP 143
            K++  P
Sbjct: 1318 KEQPQP 1323


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 1/71 (1%)

Query: 40  EEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQ-THENM 98
           + EE ++E+KEKEE E++K + GS+   Q E+  E    E +  T +   K  Q + E  
Sbjct: 179 DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEP 238

Query: 99  SQLSEEEQNKD 109
            Q  E EQ  D
Sbjct: 239 KQEEEREQGSD 249



 Score = 35.0 bits (79), Expect = 0.046
 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 3/73 (4%)

Query: 16  KLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQ--- 72
           KL  K  E    L  +K + E   +  EEEE+ +++EE ++K  E+    R + EI+   
Sbjct: 553 KLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRR 612

Query: 73  PEAAVQEMRPPTD 85
            EAA +  + P D
Sbjct: 613 AEAAEKRQKMPED 625



 Score = 32.0 bits (71), Expect = 0.39
 Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 13/87 (14%)

Query: 33  DEPEVEEEEEEE----------EEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRP 82
           +EP+ EEE E+           EEE+KE+ E E+ +LE     R + E   + A +  R 
Sbjct: 236 EEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARI 295

Query: 83  PTD---LTHFKENQTHENMSQLSEEEQ 106
             +       +E +  E   ++ EEE+
Sbjct: 296 EAEEKAAAQERERREAEERERMREEEK 322



 Score = 30.0 bits (66), Expect = 1.5
 Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 7/119 (5%)

Query: 30  RMKDEPEVEEEEE-----EEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPT 84
           R+K+E +   EE      EEEE+ K +E+   K+LE+   +  + +I+ E   Q++    
Sbjct: 358 RIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKW 417

Query: 85  DLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKKTP 143
            +   K  +     + L ++ + K  +  +K   L       K E  K   ++KK K P
Sbjct: 418 -VNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDE-KIKKDKEP 474



 Score = 28.5 bits (62), Expect = 4.3
 Identities = 23/109 (21%), Positives = 50/109 (45%), Gaps = 10/109 (9%)

Query: 33  DEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTHFKEN 92
           +E    +E E  E EE+E+   E+K+  +    R + + + + A +E +   +    +E 
Sbjct: 298 EEKAAAQERERREAEERERMREEEKRAAE---ERQRIKEEEKRAAEERQRIKE----EEK 350

Query: 93  QTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKK 141
           +  E   ++ EEE+    +   +  +       +K E +K   +L++KK
Sbjct: 351 RAAEERQRIKEEEKRAAEE---RQRARAEEEEKAKVEEQKRNKQLEEKK 396



 Score = 28.1 bits (61), Expect = 5.6
 Identities = 14/50 (28%), Positives = 28/50 (56%), Gaps = 2/50 (4%)

Query: 32  KDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMR 81
           ++   ++EEE+   EE +  +E EK+  E+   +R + E   +A V+E +
Sbjct: 340 EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEE--EKAKVEEQK 387


>gi|87298939 hypothetical protein LOC131831 [Homo sapiens]
          Length = 663

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 27/65 (41%), Positives = 36/65 (55%), Gaps = 2/65 (3%)

Query: 15 GKLPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPE 74
          GK   K  E    L   ++E EVEEEEEE EEEE+E EE E++ +E+  +   Q    PE
Sbjct: 14 GKKDQKESE--EELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPE 71

Query: 75 AAVQE 79
             +E
Sbjct: 72 TFSEE 76



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 15/47 (31%), Positives = 28/47 (59%)

Query: 33 DEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQE 79
          D  + +++E EEE EE+E+EE  +++ E+      + E + E  V+E
Sbjct: 12 DPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEE 58



 Score = 29.6 bits (65), Expect = 1.9
 Identities = 25/119 (21%), Positives = 49/119 (41%), Gaps = 4/119 (3%)

Query: 38  EEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHEN 97
           ++E EEE EEE+E+EE E+++ E         E + E   +E+          E  + E 
Sbjct: 18  QKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEEY 77

Query: 98  MSQLSE-EEQNKDYQDCSKTTSLCAGPSASKN---EYEKSRGELKKKKTPGPANFHQHF 152
           + ++++  + + D+ D     +    PS +         +  E      P   + H+ F
Sbjct: 78  LWKVTDIGDYDDDFPDVRPRLASIVSPSLTSTFVPSQSATSTETPSASPPSSTSSHKSF 136


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 5/81 (6%)

Query: 33  DEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAV-----QEMRPPTDLT 87
           DE E EEEEEEEEE    +EE + +++++G     + + + EAA      +       ++
Sbjct: 444 DEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQIS 503

Query: 88  HFKENQTHENMSQLSEEEQNK 108
           + K  +  + +S+ S E+QNK
Sbjct: 504 NEKNLEPGKQISRSSGEQQNK 524


>gi|215422388 death-domain associated protein isoform a [Homo
           sapiens]
          Length = 740

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 5/81 (6%)

Query: 33  DEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAV-----QEMRPPTDLT 87
           DE E EEEEEEEEE    +EE + +++++G     + + + EAA      +       ++
Sbjct: 444 DEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQIS 503

Query: 88  HFKENQTHENMSQLSEEEQNK 108
           + K  +  + +S+ S E+QNK
Sbjct: 504 NEKNLEPGKQISRSSGEQQNK 524


>gi|215422366 death-domain associated protein isoform b [Homo
           sapiens]
          Length = 752

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 5/81 (6%)

Query: 33  DEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAV-----QEMRPPTDLT 87
           DE E EEEEEEEEE    +EE + +++++G     + + + EAA      +       ++
Sbjct: 456 DEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQIS 515

Query: 88  HFKENQTHENMSQLSEEEQNK 108
           + K  +  + +S+ S E+QNK
Sbjct: 516 NEKNLEPGKQISRSSGEQQNK 536


>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
          Length = 587

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 5/92 (5%)

Query: 32  KDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTHFKE 91
           ++E E EEEEEEEEEEE+ ++  + +K    S     P     A V    PP D++ F  
Sbjct: 380 EEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTGEPAPVLSSPPPADVSTFLA 439

Query: 92  NQTHENMSQLSEEE-----QNKDYQDCSKTTS 118
             + E + +L  +      Q  D  D  K  S
Sbjct: 440 FPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVS 471



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 21/52 (40%), Positives = 29/52 (55%)

Query: 33  DEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPT 84
           DE E EEEE EEEEEE E+EE E ++ E+      + E Q     ++   P+
Sbjct: 360 DEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPS 411



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 24/69 (34%), Positives = 34/69 (49%)

Query: 34  EPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQ 93
           + E EEEEEE EEEE+E EE E++  E+      + E +P+   Q  +  T      +  
Sbjct: 359 DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPN 418

Query: 94  THENMSQLS 102
           T E    LS
Sbjct: 419 TGEPAPVLS 427


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 13/111 (11%)

Query: 29  MRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTH 88
           + +K+ PE EEEEEEEEEE++E EE E+   E+G     + + + E    E      L  
Sbjct: 525 IEVKENPEEEEEEEEEEEEDEESEEEEE---EEGESEGSEGDEEDEKVSDEKDSGKTLDK 581

Query: 89  FKENQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKK 139
               +   +    S++++ K+ +   K          +K   EK R E  K
Sbjct: 582 KPSKEMSSDSEYDSDDDRTKEERAYDK----------AKRRIEKRRLEHSK 622



 Score = 36.2 bits (82), Expect = 0.021
 Identities = 30/121 (24%), Positives = 58/121 (47%), Gaps = 14/121 (11%)

Query: 32  KDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEA-------AVQEMRPPT 84
           + E E  E+E+ E +++KEKE  E+ K E   L++ Q E +  A         Q +  P+
Sbjct: 376 RKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPS 435

Query: 85  DLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKKTPG 144
             +  K+   +E+  +  +  Q  + ++ S++  LCA     +      +G  +K++TP 
Sbjct: 436 KDSLPKKRPIYEDKKR-KKIPQQLESKEVSESMELCAAVEVME------QGVPEKEETPP 488

Query: 145 P 145
           P
Sbjct: 489 P 489



 Score = 33.1 bits (74), Expect = 0.18
 Identities = 29/125 (23%), Positives = 49/125 (39%), Gaps = 17/125 (13%)

Query: 27  TLMRMKDEPEVEEEEEEEEEEEK-----EKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMR 81
           T+ + K E +  E ++ +EE+ K     EKEE E  K +       Q + + E    ++ 
Sbjct: 227 TVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVT 286

Query: 82  PPTDLTHFKENQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKK 141
             T +    E +     +   + E +K  +D              K + EK   E +KKK
Sbjct: 287 VDTGVIPASEEKAETPTAAEDDNEGDKKKKD------------KKKKKGEKEEKEKEKKK 334

Query: 142 TPGPA 146
            P  A
Sbjct: 335 GPSKA 339



 Score = 32.7 bits (73), Expect = 0.23
 Identities = 16/35 (45%), Positives = 22/35 (62%)

Query: 21  HPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHE 55
           H E+       ++E E EEE+EE EEEE+E+ E E
Sbjct: 524 HIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESE 558



 Score = 32.3 bits (72), Expect = 0.30
 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 2/71 (2%)

Query: 2   KGGSKFKLKTRTAGKLPPKHPELP--PTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKL 59
           +G  K K K +  G+   K  E    P+   +K   E   + +EEEE +K +EE   K+L
Sbjct: 310 EGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRL 369

Query: 60  EDGSLSRPQPE 70
           E+    R + E
Sbjct: 370 EELEAKRKEEE 380



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 28/125 (22%), Positives = 57/125 (45%), Gaps = 26/125 (20%)

Query: 19  PKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQ 78
           P   E   T    +D+ E +++++++++++ EKEE EK+K +  S          +A V+
Sbjct: 293 PASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPS----------KATVK 342

Query: 79  EMRPPTDLTHFKENQTHENMSQLSEEE--QNKDYQDCSKTTSLCAGPSASKNEYEKSRGE 136
            M+              E +++L EEE  Q ++ ++  K           +   E+ + E
Sbjct: 343 AMQ--------------EALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRE 388

Query: 137 LKKKK 141
            KK+K
Sbjct: 389 RKKQK 393



 Score = 27.7 bits (60), Expect = 7.4
 Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 1/43 (2%)

Query: 20  KHPELPPTLMRMKDEPEVEEEEEEEE-EEEKEKEEHEKKKLED 61
           ++PE        ++E E  EEEEEEE E E  + + E +K+ D
Sbjct: 529 ENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSD 571


>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 185

 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 21/48 (43%), Positives = 32/48 (66%)

Query: 33  DEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEM 80
           +E EVEEEEEE EEEEKE+E+ E ++ E+    + + E + E   ++M
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKM 166



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 18/30 (60%), Positives = 26/30 (86%)

Query: 32  KDEPEVEEEEEEEEEEEKEKEEHEKKKLED 61
           K+E E EEE+EEE+EE++E+EE E KK+E+
Sbjct: 139 KEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 22/49 (44%), Positives = 33/49 (67%), Gaps = 1/49 (2%)

Query: 32  KDEPEVEEEE-EEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQE 79
           ++E EVEEEE EEE+EE++E+EE E++K ED      + +   E  V+E
Sbjct: 125 EEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 18/45 (40%), Positives = 31/45 (68%)

Query: 17  LPPKHPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLED 61
           LP +  E+      +++E + EE+EE+EEEEEKE+E+ E ++ E+
Sbjct: 116 LPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEE 160



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 20/43 (46%), Positives = 27/43 (62%)

Query: 37  VEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQE 79
           VEEEE EEEEEE E+EE E++K ED      + E + +   +E
Sbjct: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEE 160



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 19/46 (41%), Positives = 29/46 (63%)

Query: 34  EPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQE 79
           E E EE EEEE+EEEKE++E E++K E+      + E + +   +E
Sbjct: 124 EEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEE 169



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 17/58 (29%), Positives = 36/58 (62%)

Query: 32  KDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTHF 89
           ++E E EE+EEE+EE+E+E+E+ E+K+ ++    +   +++ E   +E+      T +
Sbjct: 127 EEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQY 184



 Score = 32.0 bits (71), Expect = 0.39
 Identities = 15/40 (37%), Positives = 26/40 (65%)

Query: 35  PEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPE 74
           P  EEE EEEEEE +E+E+ E+K+ ++    + + + + E
Sbjct: 117 PVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDE 156



 Score = 28.9 bits (63), Expect = 3.3
 Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 3/69 (4%)

Query: 42  EEEEEEEKEKEEHEKKKLEDGSLSRPQPEIQPEAAVQEMRPPTDLTHFKENQTHENMSQL 101
           EEEE EE+E+E  E++K E+      + E + E    E     +    +E +  E   ++
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE---EI 175

Query: 102 SEEEQNKDY 110
             E Q   Y
Sbjct: 176 DTEIQRTQY 184


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.126    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,628,730
Number of Sequences: 37866
Number of extensions: 586552
Number of successful extensions: 30122
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 981
Number of HSP's successfully gapped in prelim test: 632
Number of HSP's that attempted gapping in prelim test: 8304
Number of HSP's gapped (non-prelim): 9347
length of query: 210
length of database: 18,247,518
effective HSP length: 98
effective length of query: 112
effective length of database: 14,536,650
effective search space: 1628104800
effective search space used: 1628104800
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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