Guide to the Human Genome
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Search of human proteins with 117956373

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 7 [Homo sapiens]
         (663 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do...  1345   0.0  
gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do...  1317   0.0  
gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH do...  1316   0.0  
gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]   1292   0.0  
gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH do...  1286   0.0  
gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea...  1265   0.0  
gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea...  1262   0.0  
gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat...   970   0.0  
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]               806   0.0  
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]               762   0.0  
gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]              564   e-161
gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]           466   e-131
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]         458   e-129
gi|239755300 PREDICTED: similar to centaurin, gamma-like family,...   349   5e-96
gi|239755288 PREDICTED: cyclin Y-like 2 [Homo sapiens]                176   6e-44
gi|239749780 PREDICTED: cyclin Y-like 2 [Homo sapiens]                176   6e-44
gi|239744040 PREDICTED: cyclin Y-like 2 [Homo sapiens]                176   6e-44
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma...   146   7e-35
gi|187608516 centaurin, beta 2 [Homo sapiens]                         132   8e-31
gi|46094081 development and differentiation enhancing factor 1 [...   130   4e-30
gi|7661880 centaurin beta1 [Homo sapiens]                             129   7e-30
gi|206725422 G protein-coupled receptor kinase interacting ArfGA...   125   2e-28
gi|206725420 G protein-coupled receptor kinase interacting ArfGA...   125   2e-28
gi|21237786 G protein-coupled receptor kinase interacting ArfGAP...   125   2e-28
gi|17149830 G protein-coupled receptor kinase interacting ArfGAP...   125   2e-28
gi|17149832 G protein-coupled receptor kinase interacting ArfGAP...   125   2e-28
gi|206725415 G protein-coupled receptor kinase interacting ArfGA...   125   2e-28
gi|146231998 G protein-coupled receptor kinase interactor 1 isof...   123   6e-28
gi|41393573 G protein-coupled receptor kinase interactor 1 isofo...   123   6e-28
gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domai...   117   4e-26

>gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 7 [Homo sapiens]
          Length = 663

 Score = 1345 bits (3480), Expect = 0.0
 Identities = 663/663 (100%), Positives = 663/663 (100%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60

Query: 61  DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQYS 120
           DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQYS
Sbjct: 61  DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQYS 120

Query: 121 LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHITK 180
           LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHITK
Sbjct: 121 LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHITK 180

Query: 181 NRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD 240
           NRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD
Sbjct: 181 NRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD 240

Query: 241 KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM 300
           KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM
Sbjct: 241 KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM 300

Query: 301 KYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKSDGLSKDMDTGLGDSICFSPSISS 360
           KYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKSDGLSKDMDTGLGDSICFSPSISS
Sbjct: 301 KYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKSDGLSKDMDTGLGDSICFSPSISS 360

Query: 361 TTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL 420
           TTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL
Sbjct: 361 TTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL 420

Query: 421 ASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS 480
           ASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS
Sbjct: 421 ASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS 480

Query: 481 GIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEK 540
           GIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEK
Sbjct: 481 GIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEK 540

Query: 541 ERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGD 600
           ERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGD
Sbjct: 541 ERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGD 600

Query: 601 GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD 660
           GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD
Sbjct: 601 GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD 660

Query: 661 ECV 663
           ECV
Sbjct: 661 ECV 663


>gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 4 [Homo sapiens]
          Length = 663

 Score = 1317 bits (3408), Expect = 0.0
 Identities = 650/663 (98%), Positives = 656/663 (98%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGA DRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60

Query: 61  DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQYS 120
           DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTV FSQQYS
Sbjct: 61  DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVRFSQQYS 120

Query: 121 LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHITK 180
           LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHI K
Sbjct: 121 LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHIMK 180

Query: 181 NRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD 240
            RNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD
Sbjct: 181 KRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD 240

Query: 241 KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM 300
           KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM
Sbjct: 241 KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM 300

Query: 301 KYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKSDGLSKDMDTGLGDSICFSPSISS 360
           K IHKKEIDLQTSTIKVPGKWPSLAT ACTPIS+SKS+GLSKDMDTGLGDSICFSPSISS
Sbjct: 301 KNIHKKEIDLQTSTIKVPGKWPSLATSACTPISTSKSNGLSKDMDTGLGDSICFSPSISS 360

Query: 361 TTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL 420
           TT PKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL
Sbjct: 361 TTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL 420

Query: 421 ASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS 480
           ASLQSCESSKSKSQLTSQS+AMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS
Sbjct: 421 ASLQSCESSKSKSQLTSQSKAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS 480

Query: 481 GIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEK 540
           GIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQG+TKP+EKSTREEK
Sbjct: 481 GIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEK 540

Query: 541 ERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGD 600
           ERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGD
Sbjct: 541 ERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGD 600

Query: 601 GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD 660
           GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD
Sbjct: 601 GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD 660

Query: 661 ECV 663
           +CV
Sbjct: 661 KCV 663


>gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 8 [Homo sapiens]
          Length = 663

 Score = 1316 bits (3406), Expect = 0.0
 Identities = 651/663 (98%), Positives = 654/663 (98%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGA DRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60

Query: 61  DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQYS 120
           DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTV FSQQYS
Sbjct: 61  DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVRFSQQYS 120

Query: 121 LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHITK 180
           LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHI K
Sbjct: 121 LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHIMK 180

Query: 181 NRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD 240
            RNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD
Sbjct: 181 KRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD 240

Query: 241 KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM 300
           KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM
Sbjct: 241 KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM 300

Query: 301 KYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKSDGLSKDMDTGLGDSICFSPSISS 360
           K IHKKEIDLQTSTIKVPGKWPSLAT ACTPISSSKS+GLSKDMDTGLGDSICFSPSISS
Sbjct: 301 KNIHKKEIDLQTSTIKVPGKWPSLATSACTPISSSKSNGLSKDMDTGLGDSICFSPSISS 360

Query: 361 TTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL 420
           TT PKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL
Sbjct: 361 TTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL 420

Query: 421 ASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS 480
           ASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS
Sbjct: 421 ASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS 480

Query: 481 GIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEK 540
           GIH SLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQG+TKP+EKSTREEK
Sbjct: 481 GIHHSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEK 540

Query: 541 ERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGD 600
           ERWIRSKYEEKLFLAPLPCTELSLGQQLL ATADEDLQTAILLLAHGSREEVNETCGEGD
Sbjct: 541 ERWIRSKYEEKLFLAPLPCTELSLGQQLLWATADEDLQTAILLLAHGSREEVNETCGEGD 600

Query: 601 GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD 660
           GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD
Sbjct: 601 GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD 660

Query: 661 ECV 663
           ECV
Sbjct: 661 ECV 663


>gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]
          Length = 686

 Score = 1292 bits (3343), Expect = 0.0
 Identities = 645/686 (94%), Positives = 650/686 (94%), Gaps = 23/686 (3%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTCRVHPSVSLEFDQQQGSVCPSESE YEAGA DRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESETYEAGARDRMAGAPMAAAVQPAEVTVEVGE 60

Query: 61  DLHMHHVRDREMPEALEFN-----------------------PSANPEASTIFQRNSQTD 97
           DLHMHHVRDREMPEALEFN                       PSANPEASTIFQRNSQTD
Sbjct: 61  DLHMHHVRDREMPEALEFNLSANPESSTIFQRNSQTEALEFNPSANPEASTIFQRNSQTD 120

Query: 98  VVEIRRSNCTNHVSTVHFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157
           VVEIRRSNCTNHVS V FSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA
Sbjct: 121 VVEIRRSNCTNHVSAVRFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180

Query: 158 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217
           DR+LSIPDEQLHSFAVSTVHI K RNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP
Sbjct: 181 DRTLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240

Query: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277
           TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 241 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300

Query: 278 KKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKS 337
           KKKYVTLCSNG+LTYYSSLGDYMK IHKKEIDLQTSTIKVPGKWPSLAT ACTPISSSKS
Sbjct: 301 KKKYVTLCSNGMLTYYSSLGDYMKNIHKKEIDLQTSTIKVPGKWPSLATSACTPISSSKS 360

Query: 338 DGLSKDMDTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397
           +GLSKDMDTGLGDSICFSPSISSTT PKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420

Query: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 457
           WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV
Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480

Query: 458 DCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517
           DCETQNPKWASLNLGVLMCIECSGIHRSLG  LSRVRSLELDDWPVELRKVMSSI NDLA
Sbjct: 481 DCETQNPKWASLNLGVLMCIECSGIHRSLGPHLSRVRSLELDDWPVELRKVMSSIVNDLA 540

Query: 518 NSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 577
           NSIWEGSSQG+TKP+EKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL
Sbjct: 541 NSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 600

Query: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637
           QTAILLLAHGS EEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA
Sbjct: 601 QTAILLLAHGSCEEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660

Query: 638 LTYARQASSQECINVLLQYGCPDECV 663
           LTYARQASSQECINVLLQYGCPDECV
Sbjct: 661 LTYARQASSQECINVLLQYGCPDECV 686


>gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 5 [Homo sapiens]
          Length = 686

 Score = 1286 bits (3327), Expect = 0.0
 Identities = 643/686 (93%), Positives = 649/686 (94%), Gaps = 23/686 (3%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTC VHPSVSLEFDQQQGSVCPSESEIYEAGA DRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1   MGNILTCCVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60

Query: 61  DLHMHHVRDREMPEALEF-----------------------NPSANPEASTIFQRNSQTD 97
           DLHMHH+RD+EMPEALEF                       NPSANPEASTIFQRNSQTD
Sbjct: 61  DLHMHHIRDQEMPEALEFSLSANPEASTIFQRNSQTDALEFNPSANPEASTIFQRNSQTD 120

Query: 98  VVEIRRSNCTNHVSTVHFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157
           VVEIRRSNCTNHVST  FSQQYS CSTIFLDDSTA QHYLTMTIISVTLEIPHHITQRDA
Sbjct: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTASQHYLTMTIISVTLEIPHHITQRDA 180

Query: 158 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217
           DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP
Sbjct: 181 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240

Query: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277
           TPVCKRSMRWSNLFTSEKGS PDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 241 TPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300

Query: 278 KKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKS 337
           KKKYVTLCSNGVLTYYSSLGDYMK IHKKEIDL+TSTIKVPGKWPSLAT AC PISSSKS
Sbjct: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360

Query: 338 DGLSKDMDTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397
           +GLSKDMDTGLGDSICFSPSISSTT PKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420

Query: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 457
           WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV
Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480

Query: 458 DCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517
           D ETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA
Sbjct: 481 DYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 540

Query: 518 NSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 577
           NSIWEGSSQG+TKP+ KSTREEKERWIRSKYEEKLFLAPLPCTELSLGQ LLRATADEDL
Sbjct: 541 NSIWEGSSQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQHLLRATADEDL 600

Query: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637
           QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA
Sbjct: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660

Query: 638 LTYARQASSQECINVLLQYGCPDECV 663
           LTYARQASSQECINVLLQYGCPDECV
Sbjct: 661 LTYARQASSQECINVLLQYGCPDECV 686


>gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
           and PH domain 9 [Homo sapiens]
          Length = 684

 Score = 1265 bits (3273), Expect = 0.0
 Identities = 636/686 (92%), Positives = 642/686 (93%), Gaps = 25/686 (3%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60

Query: 61  DLHMHHVRDREMPEALEFN-----------------------PSANPEASTIFQRNSQTD 97
           DLHMH VRDREMPEALEFN                        SANPEASTIFQRNSQTD
Sbjct: 61  DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120

Query: 98  VVEIRRSNCTNHVSTVHFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157
           VVEIRRSNCTNHVST  FSQQYS CSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA
Sbjct: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180

Query: 158 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217
           DRSLSIPDEQLHSFAVSTVHI K RNGGGSLNNYSSSIP TPSTSQEDPQFSVPPTANTP
Sbjct: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240

Query: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277
           TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 241 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300

Query: 278 KKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKS 337
           KKKYVTLCSNGVLTYYSSLGDYMK IHKKEIDL+TSTIKVPGKWPSLAT AC PISSSKS
Sbjct: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360

Query: 338 DGLSKDMDTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397
           +GLSKDMDTGLGDSICFSP ISSTT PKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420

Query: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 457
           WHFEATTYEERDAWVQAIQSQILASLQSC+SSKSKSQLTSQSEAMALQSIQNMRGNAHCV
Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480

Query: 458 DCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517
           DCETQNPKWASLNLGVLMCIECSGIHRS GTRLSRVRSLELDDWPVELRKVMSSIGN+LA
Sbjct: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540

Query: 518 NSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 577
           NSIWEGSSQG+TKP+ KSTREEKE WIRSKYEEKLFLAPLPCTELSLGQQLLRAT DEDL
Sbjct: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600

Query: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637
           QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL QLL   GVDVMARDAHGNTA
Sbjct: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTA 658

Query: 638 LTYARQASSQECINVLLQYGCPDECV 663
           LTYARQASSQECINVLLQYGCPDECV
Sbjct: 659 LTYARQASSQECINVLLQYGCPDECV 684


>gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
           and PH domain 10 [Homo sapiens]
          Length = 684

 Score = 1262 bits (3266), Expect = 0.0
 Identities = 635/686 (92%), Positives = 641/686 (93%), Gaps = 25/686 (3%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE
Sbjct: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60

Query: 61  DLHMHHVRDREMPEALEFN-----------------------PSANPEASTIFQRNSQTD 97
           DLHMH VRDREMPEALEFN                        SANPEASTIFQRNSQTD
Sbjct: 61  DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120

Query: 98  VVEIRRSNCTNHVSTVHFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157
           VVEIRRSNCTNHVST  FSQQYS CSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA
Sbjct: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180

Query: 158 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217
           DRSLSIPDEQLHSFAVSTVHI K RNGGGSLNNYSSSIP TPSTSQEDPQFSVPPTANTP
Sbjct: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240

Query: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277
           TPVCK SMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW
Sbjct: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300

Query: 278 KKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKS 337
           KKKYVTLCSNGVLTYYSSLGDYMK IHKKEIDL+TSTIKVPGKWPSLAT AC PISSSKS
Sbjct: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360

Query: 338 DGLSKDMDTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397
           +GLSKDMDTGLGDSICFSP ISSTT PKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT
Sbjct: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420

Query: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 457
           WHFEATTYEERDAWVQAIQSQILASLQSC+SSKSKSQLTSQSEAMALQSIQNMRGNAHCV
Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480

Query: 458 DCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517
           DCETQNPKWASLNLGVLMCIECSGIHRS GTRLSRVRSLELDDWPVELRKVMSSIGN+LA
Sbjct: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540

Query: 518 NSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 577
           NSIWEGSSQG+TKP+ KSTREEKE WIRSKYEEKLFLAPLPCTELSLGQQLLRAT DEDL
Sbjct: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600

Query: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637
           QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL QLL   GVDVMARDAHGNTA
Sbjct: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTA 658

Query: 638 LTYARQASSQECINVLLQYGCPDECV 663
           LTYARQASSQECINVLLQYGCPDECV
Sbjct: 659 LTYARQASSQECINVLLQYGCPDECV 684


>gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating
           protein 11 [Homo sapiens]
          Length = 550

 Score =  970 bits (2507), Expect = 0.0
 Identities = 490/550 (89%), Positives = 504/550 (91%), Gaps = 25/550 (4%)

Query: 139 MTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPST 198
           MTIISVTLEI HHIT+RDADRSL+I DEQL+SFA STVHITK RNGGGSLNNYSSSIP T
Sbjct: 1   MTIISVTLEIHHHITERDADRSLTILDEQLYSFAFSTVHITKKRNGGGSLNNYSSSIPLT 60

Query: 199 PSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRA 258
           PSTSQED  FSVPPTANTPTP+CK+SM WSNLFTSEKGSDPDK RKA E+HADTIGSGRA
Sbjct: 61  PSTSQEDLYFSVPPTANTPTPICKQSMGWSNLFTSEKGSDPDKGRKALESHADTIGSGRA 120

Query: 259 IPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVP 318
           IPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMK IHKKEIDL+TSTIKVP
Sbjct: 121 IPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVP 180

Query: 319 GKWPSLATLACTPISSSKSDGLSKDM---------DTGLGDSICFSPSISSTTIPKLNPP 369
           GKWPSLAT AC PISSSKS+GLSKDM         D GLGDSICFSPSISSTT PKLN P
Sbjct: 181 GKWPSLATSACAPISSSKSNGLSKDMEALHMSANSDIGLGDSICFSPSISSTTSPKLNLP 240

Query: 370 PSPHANKKKHLKKKSTNN----------------FMIVSATGQTWHFEATTYEERDAWVQ 413
           PSPHANKKKHLKKKSTNN                FMIVS TGQT HF+ATTYEERDAWVQ
Sbjct: 241 PSPHANKKKHLKKKSTNNLKDDGLSSTAEEEEEKFMIVSVTGQTCHFKATTYEERDAWVQ 300

Query: 414 AIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGV 473
           AIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGN+HCVDCETQNPKWASLNLGV
Sbjct: 301 AIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNSHCVDCETQNPKWASLNLGV 360

Query: 474 LMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTE 533
           LMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQG+TKP+ 
Sbjct: 361 LMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSI 420

Query: 534 KSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVN 593
           +STREEKERWIRSKYE KLFLAPLPCTELSLGQ LLRATADEDL+TAILLLAHGSREEVN
Sbjct: 421 ESTREEKERWIRSKYEHKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSREEVN 480

Query: 594 ETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVL 653
           ETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVL
Sbjct: 481 ETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVL 540

Query: 654 LQYGCPDECV 663
           LQYGCPDECV
Sbjct: 541 LQYGCPDECV 550


>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
          Length = 804

 Score =  806 bits (2082), Expect = 0.0
 Identities = 410/532 (77%), Positives = 452/532 (84%), Gaps = 32/532 (6%)

Query: 162 SIPDEQLHSFA----VSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217
           S+P+   HS      VS VHI++  NGGGSL++YSSS+PSTPSTSQ++ +  VPPTANTP
Sbjct: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304

Query: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 276
           TPV K+S R SNLFTS KGSDPDKE+K  E+ AD+IGSGRAIPIKQGMLLKRSGK L K 
Sbjct: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364

Query: 277 WKKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSK 336
           WKKKYVTLC NGVLTY+ SL DYM+ +H KEIDL  +T+KVPGK P  AT AC PISS K
Sbjct: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424

Query: 337 SDGLSKDM---------DTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNN 387
           ++GLSKDM         DTGLGDS+C SPSISSTT PKL+PPPSPHAN+KKH +KKST+N
Sbjct: 425 TNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSN 484

Query: 388 F------------------MIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESS 429
           F                  +IVS TGQTWHFEATTYEERDAWVQAI+SQILASLQSCESS
Sbjct: 485 FKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESS 544

Query: 430 KSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTR 489
           K+KS+LTSQSEAMALQSI+NMRGN+HCVDCETQNP WASLNLG LMCIECSGIHR+LGT 
Sbjct: 545 KNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTH 604

Query: 490 LSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSKYE 549
           LSRVRSL+LDDWPVEL KVMSSIGN+LANS+WE SSQGRTKP+  STREEKERWIR+KYE
Sbjct: 605 LSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYE 664

Query: 550 EKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLAC 609
           +KLFLAPLPCTELSLGQ LLRATADEDL+TAILLLAHGSR+EVNETCGEGDG TALHLAC
Sbjct: 665 QKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLAC 724

Query: 610 RKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 661
           RKGNVVLAQLLIWYGVDV ARDAHGNTAL YARQASSQECI+VLLQYGCPDE
Sbjct: 725 RKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE 776


>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
          Length = 857

 Score =  762 bits (1968), Expect = 0.0
 Identities = 401/585 (68%), Positives = 449/585 (76%), Gaps = 85/585 (14%)

Query: 162 SIPDEQLHSFA----VSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217
           S+P+   HS      VS VHI++  NGGGSL++YSSS+PSTPSTSQ++ +  VPPTANTP
Sbjct: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304

Query: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 276
           TPV K+S R SNLFTS KGSDPDKE+K  E+ AD+IGSGRAIPIKQGMLLKRSGK L K 
Sbjct: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364

Query: 277 WKKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWP-------------- 322
           WKKKYVTLC NGVLTY+ SL DYM+ +H KEIDL  +T+KVPGK P              
Sbjct: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424

Query: 323 ------SLATLACTPIS--------------------SSKSDGLSK-------------- 342
                  +++L  +P S                    +S+ DG+ +              
Sbjct: 425 TNGLSKDMSSLHISPNSGNVTSASGSQMASGISLVSFNSRPDGMHQRSYSVSSADQWSEA 484

Query: 343 --------DMDTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNNF------ 388
                     DTGLGDS+C SPSISSTT PKL+PPPSPHAN+KKH +KKST+NF      
Sbjct: 485 TVIANSAISSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLS 544

Query: 389 ------------MIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLT 436
                       +IVS TGQTWHFEATTYEERDAWVQAI+SQILASLQSCESSK+KS+LT
Sbjct: 545 GTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLT 604

Query: 437 SQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSL 496
           SQSEAMALQSI+NMRGN+HCVDCETQNP WASLNLG LMCIECSGIHR+LGT LSRVRSL
Sbjct: 605 SQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSL 664

Query: 497 ELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAP 556
           +LDDWPVEL KVMSSIGN+LANS+WE SSQGRTKP+  STREEKERWIR+KYE+KLFLAP
Sbjct: 665 DLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKLFLAP 724

Query: 557 LPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL 616
           LPCTELSLGQ LLRATADEDL+TAILLLAHGSR+EVNETCGEGDG TALHLACRKGNVVL
Sbjct: 725 LPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVL 784

Query: 617 AQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 661
           AQLLIWYGVDV ARDAHGNTAL YARQASSQECI+VLLQYGCPDE
Sbjct: 785 AQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE 829


>gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]
          Length = 911

 Score =  564 bits (1454), Expect = e-161
 Identities = 302/582 (51%), Positives = 388/582 (66%), Gaps = 82/582 (14%)

Query: 162 SIPDEQLHSF----AVSTVHITKNRNGGGS-LNNYSSSIPSTPSTSQEDPQFSVPPTANT 216
           S+P+   HS     ++  VHI +  NGGGS  ++YSSS+PSTPS SQ + +      ++T
Sbjct: 301 SLPNSPSHSAVSAASIPAVHINQATNGGGSAFSDYSSSVPSTPSISQRELRIETIAASST 360

Query: 217 PTPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-K 275
           PTP+ K+S R SN+FTS KG+D D+E+KA E   D+IGSGRAIPIKQG+LLKRSGK L K
Sbjct: 361 PTPIRKQSKRRSNIFTSRKGADLDREKKAAECKVDSIGSGRAIPIKQGILLKRSGKSLNK 420

Query: 276 TWKKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACT----- 330
            WKKKYVTLC NG+LTY+ SL DYM+ IH KEIDL  +T+KVPGK    AT A       
Sbjct: 421 EWKKKYVTLCDNGLLTYHPSLHDYMQNIHGKEIDLLRTTVKVPGKRLPRATPATAPGTSP 480

Query: 331 ---------------------------------PISSS-----KSDGLSK---------- 342
                                            P+SSS     + +GL +          
Sbjct: 481 RANGLSVERSNTQLGGGTGAPHSASSASLHSERPLSSSAWAGPRPEGLHQRSCSVSSADQ 540

Query: 343 --DMDTGLGDSI---CFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNN---------- 387
             +  T L   +      P+   ++ PKL+PPPSPH+N+KKH +KKST            
Sbjct: 541 WSEATTSLPPGMQHPASGPAEVLSSSPKLDPPPSPHSNRKKHRRKKSTGTPRPDGPSSAT 600

Query: 388 --------FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQS 439
                   F++VS TGQTWHFEA+T EER+ WVQ++Q+QILASLQ C S+K K++L +Q+
Sbjct: 601 EEAEESFEFVVVSLTGQTWHFEASTAEERELWVQSVQAQILASLQGCRSAKDKTRLGNQN 660

Query: 440 EAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD 499
            A+A+Q+++ +RGN+ C+DC+  NP WASLNLG LMCIECSGIHR LG  LSRVRSL+LD
Sbjct: 661 AALAVQAVRTVRGNSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLD 720

Query: 500 DWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPC 559
           DWP EL  VM+++GN LANS+WEG+  G +KP   + REEKERWIR+KYE+KLFLAPLP 
Sbjct: 721 DWPPELLAVMTAMGNALANSVWEGALGGYSKPGPDACREEKERWIRAKYEQKLFLAPLPS 780

Query: 560 TELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQL 619
           +++ LGQQLLRA  ++DL+  ++LLAHGS+EEVNET G+GDG TALHL+    NVV  QL
Sbjct: 781 SDVPLGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGDGRTALHLSSAMANVVFTQL 840

Query: 620 LIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 661
           LIWYGVDV +RDA G T L YAR+A SQEC ++L+Q+GCP E
Sbjct: 841 LIWYGVDVRSRDARGLTPLAYARRAGSQECADILIQHGCPGE 882


>gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]
          Length = 836

 Score =  466 bits (1199), Expect = e-131
 Identities = 264/557 (47%), Positives = 344/557 (61%), Gaps = 63/557 (11%)

Query: 162 SIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTP-- 219
           S+P    HS A + V      + GG  ++YSSS+PS+P+    + +      A   TP  
Sbjct: 245 SLPSSPSHSAASTPV--AGQASNGGHTSDYSSSLPSSPNVGHRELRAEAAAVAGLSTPGS 302

Query: 220 VCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KTWK 278
           + + + R ++LF + +GSD   E+++ ++  +T GSGRAIPIKQ  LLKRSG  L K WK
Sbjct: 303 LHRAAKRRTSLFANRRGSD--SEKRSLDSRGETTGSGRAIPIKQSFLLKRSGNSLNKEWK 360

Query: 279 KKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKSD 338
           KKYVTL SNG L Y+ S+ DY+   H KE+DL  +T+KVPGK P  A  A  P  S+  +
Sbjct: 361 KKYVTLSSNGFLLYHPSINDYIHSTHGKEMDLLRTTVKVPGKRPPRAISAFGP--SASIN 418

Query: 339 GLSKDMDT-GLGDSI-------CFSPSISSTTIP-------------------------- 364
           GL KDM T  +G+ +         SPS SS   P                          
Sbjct: 419 GLVKDMSTVQMGEGLEATTPMPSPSPSPSSLQPPPDQTSKHLLKPDRNLARALSTDCTPS 478

Query: 365 ------KLNPPPSPHANKKKHLK--------------KKSTNNFMIVSATGQTWHFEATT 404
                    PPPSP   K++  K              ++    F+IVS+TGQTWHFEA +
Sbjct: 479 GDLSPLSREPPPSPMVKKQRRKKLTTPSKTEGSAGQAEEENFEFLIVSSTGQTWHFEAAS 538

Query: 405 YEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNP 464
           +EERDAWVQAI+SQILASLQ CESSK K +  SQSEA+A+Q+I+N +GN+ CVDC   NP
Sbjct: 539 FEERDAWVQAIESQILASLQCCESSKVKLRTDSQSEAVAIQAIRNAKGNSICVDCGAPNP 598

Query: 465 KWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGS 524
            WASLNLG L+CIECSGIHR+LGT LSRVRSL+LDDWP EL  V+++IGND AN +WE  
Sbjct: 599 TWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPRELTLVLTAIGNDTANRVWESD 658

Query: 525 SQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLL 584
           ++GR KP+  S+REE+E WIR+KYE+ LFLAPL  +E  LG+QL  A   +D+ T +LLL
Sbjct: 659 TRGRAKPSRDSSREERESWIRAKYEQLLFLAPLSTSEEPLGRQLWAAVQAQDVATVLLLL 718

Query: 585 AHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQA 644
           AH     ++ +  +    + LHLA    +VV+ QLL+WYG DV ARDA G TAL YARQA
Sbjct: 719 AHARHGPLDTSVEDPQLRSPLHLAAELAHVVITQLLLWYGADVAARDAQGRTALFYARQA 778

Query: 645 SSQECINVLLQYGCPDE 661
            SQ C ++LLQ+GCP E
Sbjct: 779 GSQLCADILLQHGCPGE 795


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score =  458 bits (1178), Expect = e-129
 Identities = 264/577 (45%), Positives = 344/577 (59%), Gaps = 83/577 (14%)

Query: 162  SIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTP-- 219
            S+P    HS A + V      + GG  ++YSSS+PS+P+    + +      A   TP  
Sbjct: 581  SLPSSPSHSAASTPV--AGQASNGGHTSDYSSSLPSSPNVGHRELRAEAAAVAGLSTPGS 638

Query: 220  VCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KTWK 278
            + + + R ++LF + +GSD   E+++ ++  +T GSGRAIPIKQ  LLKRSG  L K WK
Sbjct: 639  LHRAAKRRTSLFANRRGSD--SEKRSLDSRGETTGSGRAIPIKQSFLLKRSGNSLNKEWK 696

Query: 279  KKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKSD 338
            KKYVTL SNG L Y+ S+ DY+   H KE+DL  +T+KVPGK P  A  A  P  S+  +
Sbjct: 697  KKYVTLSSNGFLLYHPSINDYIHSTHGKEMDLLRTTVKVPGKRPPRAISAFGP--SASIN 754

Query: 339  GLSKDMDT-GLGDSI-------CFSPSISSTTIP-------------------------- 364
            GL KDM T  +G+ +         SPS SS   P                          
Sbjct: 755  GLVKDMSTVQMGEGLEATTPMPSPSPSPSSLQPPPDQTSKHLLKPDRNLARALSTDCTPS 814

Query: 365  ------KLNPPPSPHANKKKHLKKKSTNN------------------------------- 387
                     PPPSP   K++  K  + +                                
Sbjct: 815  GDLSPLSREPPPSPMVKKQRRKKLTTPSKTEGSAGQAEAKRKMWKLKSFGSLRNIYKAEE 874

Query: 388  ---FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMAL 444
               F+IVS+TGQTWHFEA ++EERDAWVQAI+SQILASLQ CESSK K +  SQSEA+A+
Sbjct: 875  NFEFLIVSSTGQTWHFEAASFEERDAWVQAIESQILASLQCCESSKVKLRTDSQSEAVAI 934

Query: 445  QSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVE 504
            Q+I+N +GN+ CVDC   NP WASLNLG L+CIECSGIHR+LGT LSRVRSL+LDDWP E
Sbjct: 935  QAIRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPRE 994

Query: 505  LRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSL 564
            L  V+++IGND AN +WE  ++GR KP+  S+REE+E WIR+KYE+ LFLAPL  +E  L
Sbjct: 995  LTLVLTAIGNDTANRVWESDTRGRAKPSRDSSREERESWIRAKYEQLLFLAPLSTSEEPL 1054

Query: 565  GQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYG 624
            G+QL  A   +D+ T +LLLAH     ++ +  +    + LHLA    +VV+ QLL+WYG
Sbjct: 1055 GRQLWAAVQAQDVATVLLLLAHARHGPLDTSVEDPQLRSPLHLAAELAHVVITQLLLWYG 1114

Query: 625  VDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 661
             DV ARDA G TAL YARQA SQ C ++LLQ+GCP E
Sbjct: 1115 ADVAARDAQGRTALFYARQAGSQLCADILLQHGCPGE 1151


>gi|239755300 PREDICTED: similar to centaurin, gamma-like family,
           member 1 [Homo sapiens]
          Length = 284

 Score =  349 bits (895), Expect = 5e-96
 Identities = 170/173 (98%), Positives = 173/173 (100%)

Query: 491 SRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSKYEE 550
           SRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQG+TKP+EKSTREEKERWIRSKYEE
Sbjct: 112 SRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSKYEE 171

Query: 551 KLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACR 610
           KLFLAPLPCT+LSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACR
Sbjct: 172 KLFLAPLPCTDLSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACR 231

Query: 611 KGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV 663
           KGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV
Sbjct: 232 KGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV 284



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 18/18 (100%), Positives = 18/18 (100%)

Query: 155 RDADRSLSIPDEQLHSFA 172
           RDADRSLSIPDEQLHSFA
Sbjct: 94  RDADRSLSIPDEQLHSFA 111


>gi|239755288 PREDICTED: cyclin Y-like 2 [Homo sapiens]
          Length = 362

 Score =  176 bits (446), Expect = 6e-44
 Identities = 104/177 (58%), Positives = 118/177 (66%), Gaps = 5/177 (2%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTC V P  S    Q QG VC  ESEIYEA A D +AG P+AAAV+P EVT   GE
Sbjct: 1   MGNILTCCVCPRASPGLHQHQGLVCHCESEIYEAAAGDLIAGVPVAAAVEPGEVTFVAGE 60

Query: 61  DLHMHHVRDREMPE--ALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQ 118
            LHMHH+ +REMPE   LE NPS +P+ASTIF R SQTDV E ++      VST HF+QQ
Sbjct: 61  GLHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTDVQEKKKKQLCK-VSTEHFTQQ 119

Query: 119 YSLCSTIFLDDSTAIQHYLTMTIISV--TLEIPHHITQRDADRSLSIPDEQLHSFAV 173
           YS CSTIFLDDS A Q +LTMT+ S      I  +  +RDA RSL I DEQLH   V
Sbjct: 120 YSSCSTIFLDDSIASQPHLTMTLKSXCDLGTILSYQAKRDAHRSLGIFDEQLHPLTV 176


>gi|239749780 PREDICTED: cyclin Y-like 2 [Homo sapiens]
          Length = 362

 Score =  176 bits (446), Expect = 6e-44
 Identities = 104/177 (58%), Positives = 118/177 (66%), Gaps = 5/177 (2%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTC V P  S    Q QG VC  ESEIYEA A D +AG P+AAAV+P EVT   GE
Sbjct: 1   MGNILTCCVCPRASPGLHQHQGLVCHCESEIYEAAAGDLIAGVPVAAAVEPGEVTFVAGE 60

Query: 61  DLHMHHVRDREMPE--ALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQ 118
            LHMHH+ +REMPE   LE NPS +P+ASTIF R SQTDV E ++      VST HF+QQ
Sbjct: 61  GLHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTDVQEKKKKQLCK-VSTEHFTQQ 119

Query: 119 YSLCSTIFLDDSTAIQHYLTMTIISV--TLEIPHHITQRDADRSLSIPDEQLHSFAV 173
           YS CSTIFLDDS A Q +LTMT+ S      I  +  +RDA RSL I DEQLH   V
Sbjct: 120 YSSCSTIFLDDSIASQPHLTMTLKSXCDLGTILSYQAKRDAHRSLGIFDEQLHPLTV 176


>gi|239744040 PREDICTED: cyclin Y-like 2 [Homo sapiens]
          Length = 362

 Score =  176 bits (446), Expect = 6e-44
 Identities = 104/177 (58%), Positives = 118/177 (66%), Gaps = 5/177 (2%)

Query: 1   MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60
           MGNILTC V P  S    Q QG VC  ESEIYEA A D +AG P+AAAV+P EVT   GE
Sbjct: 1   MGNILTCCVCPRASPGLHQHQGLVCHCESEIYEAAAGDLIAGVPVAAAVEPGEVTFVAGE 60

Query: 61  DLHMHHVRDREMPE--ALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQ 118
            LHMHH+ +REMPE   LE NPS +P+ASTIF R SQTDV E ++      VST HF+QQ
Sbjct: 61  GLHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTDVQEKKKKQLCK-VSTEHFTQQ 119

Query: 119 YSLCSTIFLDDSTAIQHYLTMTIISV--TLEIPHHITQRDADRSLSIPDEQLHSFAV 173
           YS CSTIFLDDS A Q +LTMT+ S      I  +  +RDA RSL I DEQLH   V
Sbjct: 120 YSSCSTIFLDDSIASQPHLTMTLKSXCDLGTILSYQAKRDAHRSLGIFDEQLHPLTV 176


>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
           3 [Homo sapiens]
          Length = 834

 Score =  146 bits (368), Expect = 7e-35
 Identities = 82/192 (42%), Positives = 114/192 (59%), Gaps = 22/192 (11%)

Query: 388 FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQ----SCES-------SKSKSQLT 436
           F ++S T ++   +A + + R AWVQA+Q+ I ++ +    SC S       S S S + 
Sbjct: 332 FEVLSPT-KSCMLQADSEKLRQAWVQAVQASIASAYRESPDSCYSERLDRTASPSTSSID 390

Query: 437 SQSEAM--------ALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGT 488
           S ++           LQ +Q++ GN+ C DC   +P+WAS+NLGVL+CIECSGIHRSLG 
Sbjct: 391 SATDTRERGVKGESVLQRVQSVAGNSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGV 450

Query: 489 RLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQ--GRTKPTEKSTREEKERWIRS 546
             S+VRSL LD W  EL K+M  +GN   N I+E   +  G  KPT  S+R++KE WI+ 
Sbjct: 451 HCSKVRSLTLDSWEPELLKLMCELGNSAVNQIYEAQCEGAGSRKPTASSSRQDKEAWIKD 510

Query: 547 KYEEKLFLAPLP 558
           KY EK FL   P
Sbjct: 511 KYVEKKFLRKAP 522



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 2/81 (2%)

Query: 561 ELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLL 620
           EL  G    RA    DL      LAHG+  EVN    E +G T L  A   G++++ + L
Sbjct: 665 ELHPGLLAHRAARARDLPALAAALAHGA--EVNWADAEDEGKTPLVQAVLGGSLIVCEFL 722

Query: 621 IWYGVDVMARDAHGNTALTYA 641
           +  G DV  RD+ G   L +A
Sbjct: 723 LQNGADVNQRDSRGRAPLHHA 743


>gi|187608516 centaurin, beta 2 [Homo sapiens]
          Length = 778

 Score =  132 bits (333), Expect = 8e-31
 Identities = 76/186 (40%), Positives = 111/186 (59%), Gaps = 21/186 (11%)

Query: 388 FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSC---------ESSKSKSQLTSQ 438
           F +VS T ++   +A + + R AW++A+Q+ I  + +           +SS S   L S 
Sbjct: 330 FEVVSPT-KSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSG 388

Query: 439 SEAM--------ALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRL 490
           +E+         ALQ +Q + GNA C DC   +P+WAS+NLG+ +CIECSGIHRSLG   
Sbjct: 389 NESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHF 448

Query: 491 SRVRSLELDDWPVELRKVMSSIGNDLANSIWEGS--SQGRTKPTEKSTREEKERWIRSKY 548
           S+VRSL LD W  EL K+M  +GND+ N ++E +    G  KP +   R+EKE +IR+KY
Sbjct: 449 SKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKP-QPGQRQEKEAYIRAKY 507

Query: 549 EEKLFL 554
            E+ F+
Sbjct: 508 VERKFV 513



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 2/85 (2%)

Query: 557 LPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL 616
           L    L+ G QL RA+ +++L      LAHG+  +VN    E +  T L  A   G++V 
Sbjct: 599 LDSKHLNPGLQLYRASYEKNLPKMAEALAHGA--DVNWANSEENKATPLIQAVLGGSLVT 656

Query: 617 AQLLIWYGVDVMARDAHGNTALTYA 641
            + L+  G +V  RD  G   L +A
Sbjct: 657 CEFLLQNGANVNQRDVQGRGPLHHA 681


>gi|46094081 development and differentiation enhancing factor 1
           [Homo sapiens]
          Length = 1129

 Score =  130 bits (327), Expect = 4e-30
 Identities = 93/293 (31%), Positives = 144/293 (49%), Gaps = 20/293 (6%)

Query: 372 PHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAI---QSQILASLQSCES 428
           P+A  KK     S N         +T+HF+A   ++  AW+  +   + + L      E 
Sbjct: 377 PNAEDKKSFDLISHN---------RTYHFQAEDEQDYVAWISVLTNSKEEALTMAFRGEQ 427

Query: 429 SKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGT 488
           S  ++ L   ++A+ ++ +Q + GN  C DC +  P W S NLG+L CIECSGIHR +G 
Sbjct: 428 SAGENSLEDLTKAI-IEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGV 486

Query: 489 RLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRT-KPTEKSTREEKERWIRSK 547
            +SR++SLELD        +  ++GN+  N I E +    + KPT  S    ++ +I +K
Sbjct: 487 HISRIQSLELDKLGTSELLLAKNVGNNSFNDIMEANLPSPSPKPTPSSDMTVRKEYITAK 546

Query: 548 YEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSR--EEVNETCGEGDGCTAL 605
           Y +  F      T  +   +LL A    DL   I + A G    E + E  G+  G TAL
Sbjct: 547 YVDHRFSRKTCSTSSAKLNELLEAIKSRDLLALIQVYAEGVELMEPLLEP-GQELGETAL 605

Query: 606 HLACR---KGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655
           HLA R   + ++ L   L+    ++  + A GNT L Y    S  EC+ +LL+
Sbjct: 606 HLAVRTADQTSLHLVDFLVQNCGNLDKQTALGNTVLHYCSMYSKPECLKLLLR 658


>gi|7661880 centaurin beta1 [Homo sapiens]
          Length = 740

 Score =  129 bits (325), Expect = 7e-30
 Identities = 99/319 (31%), Positives = 135/319 (42%), Gaps = 70/319 (21%)

Query: 391 VSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSK-------------SQLTS 437
           V +T ++   +A +      WV A+QS I ++        S              S  T 
Sbjct: 331 VVSTSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSAATL 390

Query: 438 QSEAMA-----------LQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSL 486
            S  MA           +  +Q++ GNA C DC    P+WAS+NLGV +CI+CSGIHRSL
Sbjct: 391 GSGGMARGREPGGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSL 450

Query: 487 GTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRT--KPTEKSTREEKERWI 544
           G   S+VRSL LD W  EL K+M  +GN + N I+E   +     KP    +R+EKE WI
Sbjct: 451 GVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWI 510

Query: 545 RSKYEEKLFLAPLP-----------------------------------------CTELS 563
            +KY EK FL  LP                                            L 
Sbjct: 511 HAKYVEKKFLTKLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLGSLH 570

Query: 564 LGQQLLRATA-DEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIW 622
            G  L RA+     L T    LAHG+  +VN   G  D  T L  A    +++  + L+ 
Sbjct: 571 PGALLFRASGHPPSLPTMADALAHGA--DVNWVNGGQDNATPLIQATAANSLLACEFLLQ 628

Query: 623 YGVDVMARDAHGNTALTYA 641
            G +V   D+ G   L +A
Sbjct: 629 NGANVNQADSAGRGPLHHA 647



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 568 LLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDV 627
           L++ATA   L     LL +G+     ++ G G     LH A   G+  LA L +  G D+
Sbjct: 611 LIQATAANSLLACEFLLQNGANVNQADSAGRGP----LHHATILGHTGLACLFLKRGADL 666

Query: 628 MARDAHGNTALTYARQASSQECINVL 653
            ARD+ G   LT A + ++ + + +L
Sbjct: 667 GARDSEGRDPLTIAMETANADIVTLL 692


>gi|206725422 G protein-coupled receptor kinase interacting ArfGAP 2
           isoform 5 [Homo sapiens]
          Length = 729

 Score =  125 bits (313), Expect = 2e-28
 Identities = 75/222 (33%), Positives = 114/222 (51%), Gaps = 17/222 (7%)

Query: 448 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 507
           + +R +  C DC   +P WAS+N G  +C EC  +HRSLG  +S+VR L+   WP  L +
Sbjct: 3   KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62

Query: 508 VMSSIGNDLANSIWEGS-------SQGRTKPT-EKSTREEKERWIRSKYEEKLFLAPLPC 559
           ++ ++ N+ ANSIWE S         GR K   +      K  +IR+KY+   F+  LPC
Sbjct: 63  MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122

Query: 560 ------TELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 613
                 T   L +QL  +    +L+T + LL+ G++           G T LH+A + G 
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179

Query: 614 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655
           ++ A+LL  YG D   +D+ G T + YARQ    E    L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221


>gi|206725420 G protein-coupled receptor kinase interacting ArfGAP 2
           isoform 6 [Homo sapiens]
          Length = 681

 Score =  125 bits (313), Expect = 2e-28
 Identities = 75/222 (33%), Positives = 114/222 (51%), Gaps = 17/222 (7%)

Query: 448 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 507
           + +R +  C DC   +P WAS+N G  +C EC  +HRSLG  +S+VR L+   WP  L +
Sbjct: 3   KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62

Query: 508 VMSSIGNDLANSIWEGS-------SQGRTKPT-EKSTREEKERWIRSKYEEKLFLAPLPC 559
           ++ ++ N+ ANSIWE S         GR K   +      K  +IR+KY+   F+  LPC
Sbjct: 63  MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122

Query: 560 ------TELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 613
                 T   L +QL  +    +L+T + LL+ G++           G T LH+A + G 
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179

Query: 614 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655
           ++ A+LL  YG D   +D+ G T + YARQ    E    L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221


>gi|21237786 G protein-coupled receptor kinase interacting ArfGAP 2
           isoform 3 [Homo sapiens]
          Length = 679

 Score =  125 bits (313), Expect = 2e-28
 Identities = 75/222 (33%), Positives = 114/222 (51%), Gaps = 17/222 (7%)

Query: 448 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 507
           + +R +  C DC   +P WAS+N G  +C EC  +HRSLG  +S+VR L+   WP  L +
Sbjct: 3   KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62

Query: 508 VMSSIGNDLANSIWEGS-------SQGRTKPT-EKSTREEKERWIRSKYEEKLFLAPLPC 559
           ++ ++ N+ ANSIWE S         GR K   +      K  +IR+KY+   F+  LPC
Sbjct: 63  MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122

Query: 560 ------TELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 613
                 T   L +QL  +    +L+T + LL+ G++           G T LH+A + G 
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179

Query: 614 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655
           ++ A+LL  YG D   +D+ G T + YARQ    E    L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221


>gi|17149830 G protein-coupled receptor kinase interacting ArfGAP 2
           isoform 1 [Homo sapiens]
          Length = 759

 Score =  125 bits (313), Expect = 2e-28
 Identities = 75/222 (33%), Positives = 114/222 (51%), Gaps = 17/222 (7%)

Query: 448 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 507
           + +R +  C DC   +P WAS+N G  +C EC  +HRSLG  +S+VR L+   WP  L +
Sbjct: 3   KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62

Query: 508 VMSSIGNDLANSIWEGS-------SQGRTKPT-EKSTREEKERWIRSKYEEKLFLAPLPC 559
           ++ ++ N+ ANSIWE S         GR K   +      K  +IR+KY+   F+  LPC
Sbjct: 63  MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122

Query: 560 ------TELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 613
                 T   L +QL  +    +L+T + LL+ G++           G T LH+A + G 
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179

Query: 614 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655
           ++ A+LL  YG D   +D+ G T + YARQ    E    L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221


>gi|17149832 G protein-coupled receptor kinase interacting ArfGAP 2
           isoform 2 [Homo sapiens]
          Length = 631

 Score =  125 bits (313), Expect = 2e-28
 Identities = 75/222 (33%), Positives = 114/222 (51%), Gaps = 17/222 (7%)

Query: 448 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 507
           + +R +  C DC   +P WAS+N G  +C EC  +HRSLG  +S+VR L+   WP  L +
Sbjct: 3   KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62

Query: 508 VMSSIGNDLANSIWEGS-------SQGRTKPT-EKSTREEKERWIRSKYEEKLFLAPLPC 559
           ++ ++ N+ ANSIWE S         GR K   +      K  +IR+KY+   F+  LPC
Sbjct: 63  MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122

Query: 560 ------TELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 613
                 T   L +QL  +    +L+T + LL+ G++           G T LH+A + G 
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179

Query: 614 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655
           ++ A+LL  YG D   +D+ G T + YARQ    E    L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221


>gi|206725415 G protein-coupled receptor kinase interacting ArfGAP 2
           isoform 4 [Homo sapiens]
          Length = 471

 Score =  125 bits (313), Expect = 2e-28
 Identities = 75/222 (33%), Positives = 114/222 (51%), Gaps = 17/222 (7%)

Query: 448 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 507
           + +R +  C DC   +P WAS+N G  +C EC  +HRSLG  +S+VR L+   WP  L +
Sbjct: 3   KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62

Query: 508 VMSSIGNDLANSIWEGS-------SQGRTKPT-EKSTREEKERWIRSKYEEKLFLAPLPC 559
           ++ ++ N+ ANSIWE S         GR K   +      K  +IR+KY+   F+  LPC
Sbjct: 63  MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122

Query: 560 ------TELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 613
                 T   L +QL  +    +L+T + LL+ G++           G T LH+A + G 
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179

Query: 614 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655
           ++ A+LL  YG D   +D+ G T + YARQ    E    L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221


>gi|146231998 G protein-coupled receptor kinase interactor 1 isoform
           1 [Homo sapiens]
          Length = 770

 Score =  123 bits (308), Expect = 6e-28
 Identities = 74/214 (34%), Positives = 111/214 (51%), Gaps = 17/214 (7%)

Query: 456 CVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGND 515
           C DC   +P WAS++ GVL+C EC  +HRSLG  +S V+ L    WP  L +++ ++ ++
Sbjct: 11  CADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASN 70

Query: 516 LANSIWEGS-------SQGRTKPT-EKSTREEKERWIRSKYEEKLFLAPLPC------TE 561
            ANSIWE S         GR K   +      K  +IR+KY+   F+  LPC      T 
Sbjct: 71  GANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTA 130

Query: 562 LSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLI 621
             L +QL  +    +L+T + LL+ G++           G T LH+A + G  + A+LL+
Sbjct: 131 KDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGTTPLHVAAKAGQTLQAELLV 187

Query: 622 WYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655
            YG D  + D +G T + YARQA   E    L++
Sbjct: 188 VYGADPGSPDVNGRTPIDYARQAGHHELAERLVE 221


>gi|41393573 G protein-coupled receptor kinase interactor 1 isoform
           2 [Homo sapiens]
          Length = 761

 Score =  123 bits (308), Expect = 6e-28
 Identities = 74/214 (34%), Positives = 111/214 (51%), Gaps = 17/214 (7%)

Query: 456 CVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGND 515
           C DC   +P WAS++ GVL+C EC  +HRSLG  +S V+ L    WP  L +++ ++ ++
Sbjct: 11  CADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASN 70

Query: 516 LANSIWEGS-------SQGRTKPT-EKSTREEKERWIRSKYEEKLFLAPLPC------TE 561
            ANSIWE S         GR K   +      K  +IR+KY+   F+  LPC      T 
Sbjct: 71  GANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTA 130

Query: 562 LSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLI 621
             L +QL  +    +L+T + LL+ G++           G T LH+A + G  + A+LL+
Sbjct: 131 KDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGTTPLHVAAKAGQTLQAELLV 187

Query: 622 WYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655
            YG D  + D +G T + YARQA   E    L++
Sbjct: 188 VYGADPGSPDVNGRTPIDYARQAGHHELAERLVE 221


>gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
           isoform b [Homo sapiens]
          Length = 894

 Score =  117 bits (292), Expect = 4e-26
 Identities = 88/279 (31%), Positives = 135/279 (48%), Gaps = 24/279 (8%)

Query: 396 QTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEA-----------MAL 444
           +T+HF+A    E +AWV  +Q+    +L S    +  +   S   A           + +
Sbjct: 361 RTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAGPGSWGSAGHDGEPHDLTKLLI 420

Query: 445 QSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD-DWPV 503
             +++  GN+ C DC   +P W S NLGVL CI+CSG+HR LG R SR++SL LD   P 
Sbjct: 421 AEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPS 480

Query: 504 ELRKVMSSIGNDLANSIWEGS--SQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTE 561
           EL   + ++GN   N + E    S G  KP+ +S    +  +I +KY E  F     CT 
Sbjct: 481 ELLLAL-NMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFAR--RCTP 537

Query: 562 LSLGQQLLRATADEDLQTAILLLAHGS--REEVNETCGEGDGCTALHLACRKGN---VVL 616
               Q+L  A  + DL + +   A+G    + +     +      LHLA +  N   + L
Sbjct: 538 EP--QRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPL 595

Query: 617 AQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655
              +I  G  + A+ A GNTAL YA   +  +C+ +LL+
Sbjct: 596 VDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLK 634


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.128    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,304,628
Number of Sequences: 37866
Number of extensions: 1211423
Number of successful extensions: 5372
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 336
Number of HSP's successfully gapped in prelim test: 74
Number of HSP's that attempted gapping in prelim test: 3821
Number of HSP's gapped (non-prelim): 1435
length of query: 663
length of database: 18,247,518
effective HSP length: 109
effective length of query: 554
effective length of database: 14,120,124
effective search space: 7822548696
effective search space used: 7822548696
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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