BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH domain 7 [Homo sapiens] (663 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do... 1345 0.0 gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do... 1317 0.0 gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH do... 1316 0.0 gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens] 1292 0.0 gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH do... 1286 0.0 gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 1265 0.0 gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 1262 0.0 gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat... 970 0.0 gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens] 806 0.0 gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens] 762 0.0 gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens] 564 e-161 gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens] 466 e-131 gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 458 e-129 gi|239755300 PREDICTED: similar to centaurin, gamma-like family,... 349 5e-96 gi|239755288 PREDICTED: cyclin Y-like 2 [Homo sapiens] 176 6e-44 gi|239749780 PREDICTED: cyclin Y-like 2 [Homo sapiens] 176 6e-44 gi|239744040 PREDICTED: cyclin Y-like 2 [Homo sapiens] 176 6e-44 gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma... 146 7e-35 gi|187608516 centaurin, beta 2 [Homo sapiens] 132 8e-31 gi|46094081 development and differentiation enhancing factor 1 [... 130 4e-30 gi|7661880 centaurin beta1 [Homo sapiens] 129 7e-30 gi|206725422 G protein-coupled receptor kinase interacting ArfGA... 125 2e-28 gi|206725420 G protein-coupled receptor kinase interacting ArfGA... 125 2e-28 gi|21237786 G protein-coupled receptor kinase interacting ArfGAP... 125 2e-28 gi|17149830 G protein-coupled receptor kinase interacting ArfGAP... 125 2e-28 gi|17149832 G protein-coupled receptor kinase interacting ArfGAP... 125 2e-28 gi|206725415 G protein-coupled receptor kinase interacting ArfGA... 125 2e-28 gi|146231998 G protein-coupled receptor kinase interactor 1 isof... 123 6e-28 gi|41393573 G protein-coupled receptor kinase interactor 1 isofo... 123 6e-28 gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 117 4e-26 >gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH domain 7 [Homo sapiens] Length = 663 Score = 1345 bits (3480), Expect = 0.0 Identities = 663/663 (100%), Positives = 663/663 (100%) Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60 Query: 61 DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQYS 120 DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQYS Sbjct: 61 DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQYS 120 Query: 121 LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHITK 180 LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHITK Sbjct: 121 LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHITK 180 Query: 181 NRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD 240 NRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD Sbjct: 181 NRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD 240 Query: 241 KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM 300 KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM Sbjct: 241 KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM 300 Query: 301 KYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKSDGLSKDMDTGLGDSICFSPSISS 360 KYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKSDGLSKDMDTGLGDSICFSPSISS Sbjct: 301 KYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKSDGLSKDMDTGLGDSICFSPSISS 360 Query: 361 TTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL 420 TTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL Sbjct: 361 TTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL 420 Query: 421 ASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS 480 ASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS Sbjct: 421 ASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS 480 Query: 481 GIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEK 540 GIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEK Sbjct: 481 GIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEK 540 Query: 541 ERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGD 600 ERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGD Sbjct: 541 ERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGD 600 Query: 601 GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD 660 GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD Sbjct: 601 GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD 660 Query: 661 ECV 663 ECV Sbjct: 661 ECV 663 >gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 [Homo sapiens] Length = 663 Score = 1317 bits (3408), Expect = 0.0 Identities = 650/663 (98%), Positives = 656/663 (98%) Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGA DRMAGAPMAAAVQPAEVTVEVGE Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60 Query: 61 DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQYS 120 DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTV FSQQYS Sbjct: 61 DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVRFSQQYS 120 Query: 121 LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHITK 180 LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHI K Sbjct: 121 LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHIMK 180 Query: 181 NRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD 240 RNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD Sbjct: 181 KRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD 240 Query: 241 KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM 300 KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM Sbjct: 241 KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM 300 Query: 301 KYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKSDGLSKDMDTGLGDSICFSPSISS 360 K IHKKEIDLQTSTIKVPGKWPSLAT ACTPIS+SKS+GLSKDMDTGLGDSICFSPSISS Sbjct: 301 KNIHKKEIDLQTSTIKVPGKWPSLATSACTPISTSKSNGLSKDMDTGLGDSICFSPSISS 360 Query: 361 TTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL 420 TT PKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL Sbjct: 361 TTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL 420 Query: 421 ASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS 480 ASLQSCESSKSKSQLTSQS+AMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS Sbjct: 421 ASLQSCESSKSKSQLTSQSKAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS 480 Query: 481 GIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEK 540 GIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQG+TKP+EKSTREEK Sbjct: 481 GIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEK 540 Query: 541 ERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGD 600 ERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGD Sbjct: 541 ERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGD 600 Query: 601 GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD 660 GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD Sbjct: 601 GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD 660 Query: 661 ECV 663 +CV Sbjct: 661 KCV 663 >gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH domain 8 [Homo sapiens] Length = 663 Score = 1316 bits (3406), Expect = 0.0 Identities = 651/663 (98%), Positives = 654/663 (98%) Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGA DRMAGAPMAAAVQPAEVTVEVGE Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60 Query: 61 DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQYS 120 DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTV FSQQYS Sbjct: 61 DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVRFSQQYS 120 Query: 121 LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHITK 180 LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHI K Sbjct: 121 LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHIMK 180 Query: 181 NRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD 240 RNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD Sbjct: 181 KRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD 240 Query: 241 KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM 300 KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM Sbjct: 241 KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYM 300 Query: 301 KYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKSDGLSKDMDTGLGDSICFSPSISS 360 K IHKKEIDLQTSTIKVPGKWPSLAT ACTPISSSKS+GLSKDMDTGLGDSICFSPSISS Sbjct: 301 KNIHKKEIDLQTSTIKVPGKWPSLATSACTPISSSKSNGLSKDMDTGLGDSICFSPSISS 360 Query: 361 TTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL 420 TT PKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL Sbjct: 361 TTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL 420 Query: 421 ASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS 480 ASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS Sbjct: 421 ASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS 480 Query: 481 GIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEK 540 GIH SLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQG+TKP+EKSTREEK Sbjct: 481 GIHHSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEK 540 Query: 541 ERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGD 600 ERWIRSKYEEKLFLAPLPCTELSLGQQLL ATADEDLQTAILLLAHGSREEVNETCGEGD Sbjct: 541 ERWIRSKYEEKLFLAPLPCTELSLGQQLLWATADEDLQTAILLLAHGSREEVNETCGEGD 600 Query: 601 GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD 660 GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD Sbjct: 601 GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD 660 Query: 661 ECV 663 ECV Sbjct: 661 ECV 663 >gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens] Length = 686 Score = 1292 bits (3343), Expect = 0.0 Identities = 645/686 (94%), Positives = 650/686 (94%), Gaps = 23/686 (3%) Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTCRVHPSVSLEFDQQQGSVCPSESE YEAGA DRMAGAPMAAAVQPAEVTVEVGE Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESETYEAGARDRMAGAPMAAAVQPAEVTVEVGE 60 Query: 61 DLHMHHVRDREMPEALEFN-----------------------PSANPEASTIFQRNSQTD 97 DLHMHHVRDREMPEALEFN PSANPEASTIFQRNSQTD Sbjct: 61 DLHMHHVRDREMPEALEFNLSANPESSTIFQRNSQTEALEFNPSANPEASTIFQRNSQTD 120 Query: 98 VVEIRRSNCTNHVSTVHFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157 VVEIRRSNCTNHVS V FSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA Sbjct: 121 VVEIRRSNCTNHVSAVRFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180 Query: 158 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217 DR+LSIPDEQLHSFAVSTVHI K RNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP Sbjct: 181 DRTLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240 Query: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW Sbjct: 241 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300 Query: 278 KKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKS 337 KKKYVTLCSNG+LTYYSSLGDYMK IHKKEIDLQTSTIKVPGKWPSLAT ACTPISSSKS Sbjct: 301 KKKYVTLCSNGMLTYYSSLGDYMKNIHKKEIDLQTSTIKVPGKWPSLATSACTPISSSKS 360 Query: 338 DGLSKDMDTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397 +GLSKDMDTGLGDSICFSPSISSTT PKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT Sbjct: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420 Query: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 457 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480 Query: 458 DCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517 DCETQNPKWASLNLGVLMCIECSGIHRSLG LSRVRSLELDDWPVELRKVMSSI NDLA Sbjct: 481 DCETQNPKWASLNLGVLMCIECSGIHRSLGPHLSRVRSLELDDWPVELRKVMSSIVNDLA 540 Query: 518 NSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 577 NSIWEGSSQG+TKP+EKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL Sbjct: 541 NSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 600 Query: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637 QTAILLLAHGS EEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA Sbjct: 601 QTAILLLAHGSCEEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660 Query: 638 LTYARQASSQECINVLLQYGCPDECV 663 LTYARQASSQECINVLLQYGCPDECV Sbjct: 661 LTYARQASSQECINVLLQYGCPDECV 686 >gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 [Homo sapiens] Length = 686 Score = 1286 bits (3327), Expect = 0.0 Identities = 643/686 (93%), Positives = 649/686 (94%), Gaps = 23/686 (3%) Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTC VHPSVSLEFDQQQGSVCPSESEIYEAGA DRMAGAPMAAAVQPAEVTVEVGE Sbjct: 1 MGNILTCCVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGE 60 Query: 61 DLHMHHVRDREMPEALEF-----------------------NPSANPEASTIFQRNSQTD 97 DLHMHH+RD+EMPEALEF NPSANPEASTIFQRNSQTD Sbjct: 61 DLHMHHIRDQEMPEALEFSLSANPEASTIFQRNSQTDALEFNPSANPEASTIFQRNSQTD 120 Query: 98 VVEIRRSNCTNHVSTVHFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157 VVEIRRSNCTNHVST FSQQYS CSTIFLDDSTA QHYLTMTIISVTLEIPHHITQRDA Sbjct: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTASQHYLTMTIISVTLEIPHHITQRDA 180 Query: 158 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP Sbjct: 181 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240 Query: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277 TPVCKRSMRWSNLFTSEKGS PDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW Sbjct: 241 TPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300 Query: 278 KKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKS 337 KKKYVTLCSNGVLTYYSSLGDYMK IHKKEIDL+TSTIKVPGKWPSLAT AC PISSSKS Sbjct: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360 Query: 338 DGLSKDMDTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397 +GLSKDMDTGLGDSICFSPSISSTT PKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT Sbjct: 361 NGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420 Query: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 457 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480 Query: 458 DCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517 D ETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA Sbjct: 481 DYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 540 Query: 518 NSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 577 NSIWEGSSQG+TKP+ KSTREEKERWIRSKYEEKLFLAPLPCTELSLGQ LLRATADEDL Sbjct: 541 NSIWEGSSQGQTKPSVKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQHLLRATADEDL 600 Query: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA Sbjct: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 660 Query: 638 LTYARQASSQECINVLLQYGCPDECV 663 LTYARQASSQECINVLLQYGCPDECV Sbjct: 661 LTYARQASSQECINVLLQYGCPDECV 686 >gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 [Homo sapiens] Length = 684 Score = 1265 bits (3273), Expect = 0.0 Identities = 636/686 (92%), Positives = 642/686 (93%), Gaps = 25/686 (3%) Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60 Query: 61 DLHMHHVRDREMPEALEFN-----------------------PSANPEASTIFQRNSQTD 97 DLHMH VRDREMPEALEFN SANPEASTIFQRNSQTD Sbjct: 61 DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120 Query: 98 VVEIRRSNCTNHVSTVHFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157 VVEIRRSNCTNHVST FSQQYS CSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA Sbjct: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180 Query: 158 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217 DRSLSIPDEQLHSFAVSTVHI K RNGGGSLNNYSSSIP TPSTSQEDPQFSVPPTANTP Sbjct: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240 Query: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW Sbjct: 241 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300 Query: 278 KKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKS 337 KKKYVTLCSNGVLTYYSSLGDYMK IHKKEIDL+TSTIKVPGKWPSLAT AC PISSSKS Sbjct: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360 Query: 338 DGLSKDMDTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397 +GLSKDMDTGLGDSICFSP ISSTT PKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT Sbjct: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420 Query: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 457 WHFEATTYEERDAWVQAIQSQILASLQSC+SSKSKSQLTSQSEAMALQSIQNMRGNAHCV Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480 Query: 458 DCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517 DCETQNPKWASLNLGVLMCIECSGIHRS GTRLSRVRSLELDDWPVELRKVMSSIGN+LA Sbjct: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540 Query: 518 NSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 577 NSIWEGSSQG+TKP+ KSTREEKE WIRSKYEEKLFLAPLPCTELSLGQQLLRAT DEDL Sbjct: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600 Query: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL QLL GVDVMARDAHGNTA Sbjct: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTA 658 Query: 638 LTYARQASSQECINVLLQYGCPDECV 663 LTYARQASSQECINVLLQYGCPDECV Sbjct: 659 LTYARQASSQECINVLLQYGCPDECV 684 >gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat and PH domain 10 [Homo sapiens] Length = 684 Score = 1262 bits (3266), Expect = 0.0 Identities = 635/686 (92%), Positives = 641/686 (93%), Gaps = 25/686 (3%) Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE Sbjct: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60 Query: 61 DLHMHHVRDREMPEALEFN-----------------------PSANPEASTIFQRNSQTD 97 DLHMH VRDREMPEALEFN SANPEASTIFQRNSQTD Sbjct: 61 DLHMHQVRDREMPEALEFNLSANPEASTIFQRNSQTDALEFNSSANPEASTIFQRNSQTD 120 Query: 98 VVEIRRSNCTNHVSTVHFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 157 VVEIRRSNCTNHVST FSQQYS CSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA Sbjct: 121 VVEIRRSNCTNHVSTERFSQQYSSCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDA 180 Query: 158 DRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217 DRSLSIPDEQLHSFAVSTVHI K RNGGGSLNNYSSSIP TPSTSQEDPQFSVPPTANTP Sbjct: 181 DRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240 Query: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 277 TPVCK SMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW Sbjct: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTW 300 Query: 278 KKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKS 337 KKKYVTLCSNGVLTYYSSLGDYMK IHKKEIDL+TSTIKVPGKWPSLAT AC PISSSKS Sbjct: 301 KKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKS 360 Query: 338 DGLSKDMDTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 397 +GLSKDMDTGLGDSICFSP ISSTT PKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT Sbjct: 361 NGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQT 420 Query: 398 WHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCV 457 WHFEATTYEERDAWVQAIQSQILASLQSC+SSKSKSQLTSQSEAMALQSIQNMRGNAHCV Sbjct: 421 WHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCV 480 Query: 458 DCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLA 517 DCETQNPKWASLNLGVLMCIECSGIHRS GTRLSRVRSLELDDWPVELRKVMSSIGN+LA Sbjct: 481 DCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELA 540 Query: 518 NSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDL 577 NSIWEGSSQG+TKP+ KSTREEKE WIRSKYEEKLFLAPLPCTELSLGQQLLRAT DEDL Sbjct: 541 NSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDL 600 Query: 578 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 637 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL QLL GVDVMARDAHGNTA Sbjct: 601 QTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLL--XGVDVMARDAHGNTA 658 Query: 638 LTYARQASSQECINVLLQYGCPDECV 663 LTYARQASSQECINVLLQYGCPDECV Sbjct: 659 LTYARQASSQECINVLLQYGCPDECV 684 >gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating protein 11 [Homo sapiens] Length = 550 Score = 970 bits (2507), Expect = 0.0 Identities = 490/550 (89%), Positives = 504/550 (91%), Gaps = 25/550 (4%) Query: 139 MTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPST 198 MTIISVTLEI HHIT+RDADRSL+I DEQL+SFA STVHITK RNGGGSLNNYSSSIP T Sbjct: 1 MTIISVTLEIHHHITERDADRSLTILDEQLYSFAFSTVHITKKRNGGGSLNNYSSSIPLT 60 Query: 199 PSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRA 258 PSTSQED FSVPPTANTPTP+CK+SM WSNLFTSEKGSDPDK RKA E+HADTIGSGRA Sbjct: 61 PSTSQEDLYFSVPPTANTPTPICKQSMGWSNLFTSEKGSDPDKGRKALESHADTIGSGRA 120 Query: 259 IPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVP 318 IPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMK IHKKEIDL+TSTIKVP Sbjct: 121 IPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVP 180 Query: 319 GKWPSLATLACTPISSSKSDGLSKDM---------DTGLGDSICFSPSISSTTIPKLNPP 369 GKWPSLAT AC PISSSKS+GLSKDM D GLGDSICFSPSISSTT PKLN P Sbjct: 181 GKWPSLATSACAPISSSKSNGLSKDMEALHMSANSDIGLGDSICFSPSISSTTSPKLNLP 240 Query: 370 PSPHANKKKHLKKKSTNN----------------FMIVSATGQTWHFEATTYEERDAWVQ 413 PSPHANKKKHLKKKSTNN FMIVS TGQT HF+ATTYEERDAWVQ Sbjct: 241 PSPHANKKKHLKKKSTNNLKDDGLSSTAEEEEEKFMIVSVTGQTCHFKATTYEERDAWVQ 300 Query: 414 AIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGV 473 AIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGN+HCVDCETQNPKWASLNLGV Sbjct: 301 AIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNSHCVDCETQNPKWASLNLGV 360 Query: 474 LMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTE 533 LMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQG+TKP+ Sbjct: 361 LMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSI 420 Query: 534 KSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVN 593 +STREEKERWIRSKYE KLFLAPLPCTELSLGQ LLRATADEDL+TAILLLAHGSREEVN Sbjct: 421 ESTREEKERWIRSKYEHKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSREEVN 480 Query: 594 ETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVL 653 ETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVL Sbjct: 481 ETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVL 540 Query: 654 LQYGCPDECV 663 LQYGCPDECV Sbjct: 541 LQYGCPDECV 550 >gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens] Length = 804 Score = 806 bits (2082), Expect = 0.0 Identities = 410/532 (77%), Positives = 452/532 (84%), Gaps = 32/532 (6%) Query: 162 SIPDEQLHSFA----VSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217 S+P+ HS VS VHI++ NGGGSL++YSSS+PSTPSTSQ++ + VPPTANTP Sbjct: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304 Query: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 276 TPV K+S R SNLFTS KGSDPDKE+K E+ AD+IGSGRAIPIKQGMLLKRSGK L K Sbjct: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364 Query: 277 WKKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSK 336 WKKKYVTLC NGVLTY+ SL DYM+ +H KEIDL +T+KVPGK P AT AC PISS K Sbjct: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424 Query: 337 SDGLSKDM---------DTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNN 387 ++GLSKDM DTGLGDS+C SPSISSTT PKL+PPPSPHAN+KKH +KKST+N Sbjct: 425 TNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSN 484 Query: 388 F------------------MIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESS 429 F +IVS TGQTWHFEATTYEERDAWVQAI+SQILASLQSCESS Sbjct: 485 FKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESS 544 Query: 430 KSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTR 489 K+KS+LTSQSEAMALQSI+NMRGN+HCVDCETQNP WASLNLG LMCIECSGIHR+LGT Sbjct: 545 KNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTH 604 Query: 490 LSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSKYE 549 LSRVRSL+LDDWPVEL KVMSSIGN+LANS+WE SSQGRTKP+ STREEKERWIR+KYE Sbjct: 605 LSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYE 664 Query: 550 EKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLAC 609 +KLFLAPLPCTELSLGQ LLRATADEDL+TAILLLAHGSR+EVNETCGEGDG TALHLAC Sbjct: 665 QKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLAC 724 Query: 610 RKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 661 RKGNVVLAQLLIWYGVDV ARDAHGNTAL YARQASSQECI+VLLQYGCPDE Sbjct: 725 RKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE 776 >gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens] Length = 857 Score = 762 bits (1968), Expect = 0.0 Identities = 401/585 (68%), Positives = 449/585 (76%), Gaps = 85/585 (14%) Query: 162 SIPDEQLHSFA----VSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217 S+P+ HS VS VHI++ NGGGSL++YSSS+PSTPSTSQ++ + VPPTANTP Sbjct: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304 Query: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 276 TPV K+S R SNLFTS KGSDPDKE+K E+ AD+IGSGRAIPIKQGMLLKRSGK L K Sbjct: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364 Query: 277 WKKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWP-------------- 322 WKKKYVTLC NGVLTY+ SL DYM+ +H KEIDL +T+KVPGK P Sbjct: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424 Query: 323 ------SLATLACTPIS--------------------SSKSDGLSK-------------- 342 +++L +P S +S+ DG+ + Sbjct: 425 TNGLSKDMSSLHISPNSGNVTSASGSQMASGISLVSFNSRPDGMHQRSYSVSSADQWSEA 484 Query: 343 --------DMDTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNNF------ 388 DTGLGDS+C SPSISSTT PKL+PPPSPHAN+KKH +KKST+NF Sbjct: 485 TVIANSAISSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLS 544 Query: 389 ------------MIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLT 436 +IVS TGQTWHFEATTYEERDAWVQAI+SQILASLQSCESSK+KS+LT Sbjct: 545 GTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLT 604 Query: 437 SQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSL 496 SQSEAMALQSI+NMRGN+HCVDCETQNP WASLNLG LMCIECSGIHR+LGT LSRVRSL Sbjct: 605 SQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSL 664 Query: 497 ELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAP 556 +LDDWPVEL KVMSSIGN+LANS+WE SSQGRTKP+ STREEKERWIR+KYE+KLFLAP Sbjct: 665 DLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKLFLAP 724 Query: 557 LPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL 616 LPCTELSLGQ LLRATADEDL+TAILLLAHGSR+EVNETCGEGDG TALHLACRKGNVVL Sbjct: 725 LPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVL 784 Query: 617 AQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 661 AQLLIWYGVDV ARDAHGNTAL YARQASSQECI+VLLQYGCPDE Sbjct: 785 AQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE 829 >gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens] Length = 911 Score = 564 bits (1454), Expect = e-161 Identities = 302/582 (51%), Positives = 388/582 (66%), Gaps = 82/582 (14%) Query: 162 SIPDEQLHSF----AVSTVHITKNRNGGGS-LNNYSSSIPSTPSTSQEDPQFSVPPTANT 216 S+P+ HS ++ VHI + NGGGS ++YSSS+PSTPS SQ + + ++T Sbjct: 301 SLPNSPSHSAVSAASIPAVHINQATNGGGSAFSDYSSSVPSTPSISQRELRIETIAASST 360 Query: 217 PTPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-K 275 PTP+ K+S R SN+FTS KG+D D+E+KA E D+IGSGRAIPIKQG+LLKRSGK L K Sbjct: 361 PTPIRKQSKRRSNIFTSRKGADLDREKKAAECKVDSIGSGRAIPIKQGILLKRSGKSLNK 420 Query: 276 TWKKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACT----- 330 WKKKYVTLC NG+LTY+ SL DYM+ IH KEIDL +T+KVPGK AT A Sbjct: 421 EWKKKYVTLCDNGLLTYHPSLHDYMQNIHGKEIDLLRTTVKVPGKRLPRATPATAPGTSP 480 Query: 331 ---------------------------------PISSS-----KSDGLSK---------- 342 P+SSS + +GL + Sbjct: 481 RANGLSVERSNTQLGGGTGAPHSASSASLHSERPLSSSAWAGPRPEGLHQRSCSVSSADQ 540 Query: 343 --DMDTGLGDSI---CFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNN---------- 387 + T L + P+ ++ PKL+PPPSPH+N+KKH +KKST Sbjct: 541 WSEATTSLPPGMQHPASGPAEVLSSSPKLDPPPSPHSNRKKHRRKKSTGTPRPDGPSSAT 600 Query: 388 --------FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQS 439 F++VS TGQTWHFEA+T EER+ WVQ++Q+QILASLQ C S+K K++L +Q+ Sbjct: 601 EEAEESFEFVVVSLTGQTWHFEASTAEERELWVQSVQAQILASLQGCRSAKDKTRLGNQN 660 Query: 440 EAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD 499 A+A+Q+++ +RGN+ C+DC+ NP WASLNLG LMCIECSGIHR LG LSRVRSL+LD Sbjct: 661 AALAVQAVRTVRGNSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLD 720 Query: 500 DWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPC 559 DWP EL VM+++GN LANS+WEG+ G +KP + REEKERWIR+KYE+KLFLAPLP Sbjct: 721 DWPPELLAVMTAMGNALANSVWEGALGGYSKPGPDACREEKERWIRAKYEQKLFLAPLPS 780 Query: 560 TELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQL 619 +++ LGQQLLRA ++DL+ ++LLAHGS+EEVNET G+GDG TALHL+ NVV QL Sbjct: 781 SDVPLGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGDGRTALHLSSAMANVVFTQL 840 Query: 620 LIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 661 LIWYGVDV +RDA G T L YAR+A SQEC ++L+Q+GCP E Sbjct: 841 LIWYGVDVRSRDARGLTPLAYARRAGSQECADILIQHGCPGE 882 >gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens] Length = 836 Score = 466 bits (1199), Expect = e-131 Identities = 264/557 (47%), Positives = 344/557 (61%), Gaps = 63/557 (11%) Query: 162 SIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTP-- 219 S+P HS A + V + GG ++YSSS+PS+P+ + + A TP Sbjct: 245 SLPSSPSHSAASTPV--AGQASNGGHTSDYSSSLPSSPNVGHRELRAEAAAVAGLSTPGS 302 Query: 220 VCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KTWK 278 + + + R ++LF + +GSD E+++ ++ +T GSGRAIPIKQ LLKRSG L K WK Sbjct: 303 LHRAAKRRTSLFANRRGSD--SEKRSLDSRGETTGSGRAIPIKQSFLLKRSGNSLNKEWK 360 Query: 279 KKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKSD 338 KKYVTL SNG L Y+ S+ DY+ H KE+DL +T+KVPGK P A A P S+ + Sbjct: 361 KKYVTLSSNGFLLYHPSINDYIHSTHGKEMDLLRTTVKVPGKRPPRAISAFGP--SASIN 418 Query: 339 GLSKDMDT-GLGDSI-------CFSPSISSTTIP-------------------------- 364 GL KDM T +G+ + SPS SS P Sbjct: 419 GLVKDMSTVQMGEGLEATTPMPSPSPSPSSLQPPPDQTSKHLLKPDRNLARALSTDCTPS 478 Query: 365 ------KLNPPPSPHANKKKHLK--------------KKSTNNFMIVSATGQTWHFEATT 404 PPPSP K++ K ++ F+IVS+TGQTWHFEA + Sbjct: 479 GDLSPLSREPPPSPMVKKQRRKKLTTPSKTEGSAGQAEEENFEFLIVSSTGQTWHFEAAS 538 Query: 405 YEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNP 464 +EERDAWVQAI+SQILASLQ CESSK K + SQSEA+A+Q+I+N +GN+ CVDC NP Sbjct: 539 FEERDAWVQAIESQILASLQCCESSKVKLRTDSQSEAVAIQAIRNAKGNSICVDCGAPNP 598 Query: 465 KWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGS 524 WASLNLG L+CIECSGIHR+LGT LSRVRSL+LDDWP EL V+++IGND AN +WE Sbjct: 599 TWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPRELTLVLTAIGNDTANRVWESD 658 Query: 525 SQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLL 584 ++GR KP+ S+REE+E WIR+KYE+ LFLAPL +E LG+QL A +D+ T +LLL Sbjct: 659 TRGRAKPSRDSSREERESWIRAKYEQLLFLAPLSTSEEPLGRQLWAAVQAQDVATVLLLL 718 Query: 585 AHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQA 644 AH ++ + + + LHLA +VV+ QLL+WYG DV ARDA G TAL YARQA Sbjct: 719 AHARHGPLDTSVEDPQLRSPLHLAAELAHVVITQLLLWYGADVAARDAQGRTALFYARQA 778 Query: 645 SSQECINVLLQYGCPDE 661 SQ C ++LLQ+GCP E Sbjct: 779 GSQLCADILLQHGCPGE 795 >gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] Length = 1192 Score = 458 bits (1178), Expect = e-129 Identities = 264/577 (45%), Positives = 344/577 (59%), Gaps = 83/577 (14%) Query: 162 SIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTP-- 219 S+P HS A + V + GG ++YSSS+PS+P+ + + A TP Sbjct: 581 SLPSSPSHSAASTPV--AGQASNGGHTSDYSSSLPSSPNVGHRELRAEAAAVAGLSTPGS 638 Query: 220 VCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KTWK 278 + + + R ++LF + +GSD E+++ ++ +T GSGRAIPIKQ LLKRSG L K WK Sbjct: 639 LHRAAKRRTSLFANRRGSD--SEKRSLDSRGETTGSGRAIPIKQSFLLKRSGNSLNKEWK 696 Query: 279 KKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKSD 338 KKYVTL SNG L Y+ S+ DY+ H KE+DL +T+KVPGK P A A P S+ + Sbjct: 697 KKYVTLSSNGFLLYHPSINDYIHSTHGKEMDLLRTTVKVPGKRPPRAISAFGP--SASIN 754 Query: 339 GLSKDMDT-GLGDSI-------CFSPSISSTTIP-------------------------- 364 GL KDM T +G+ + SPS SS P Sbjct: 755 GLVKDMSTVQMGEGLEATTPMPSPSPSPSSLQPPPDQTSKHLLKPDRNLARALSTDCTPS 814 Query: 365 ------KLNPPPSPHANKKKHLKKKSTNN------------------------------- 387 PPPSP K++ K + + Sbjct: 815 GDLSPLSREPPPSPMVKKQRRKKLTTPSKTEGSAGQAEAKRKMWKLKSFGSLRNIYKAEE 874 Query: 388 ---FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMAL 444 F+IVS+TGQTWHFEA ++EERDAWVQAI+SQILASLQ CESSK K + SQSEA+A+ Sbjct: 875 NFEFLIVSSTGQTWHFEAASFEERDAWVQAIESQILASLQCCESSKVKLRTDSQSEAVAI 934 Query: 445 QSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVE 504 Q+I+N +GN+ CVDC NP WASLNLG L+CIECSGIHR+LGT LSRVRSL+LDDWP E Sbjct: 935 QAIRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPRE 994 Query: 505 LRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSL 564 L V+++IGND AN +WE ++GR KP+ S+REE+E WIR+KYE+ LFLAPL +E L Sbjct: 995 LTLVLTAIGNDTANRVWESDTRGRAKPSRDSSREERESWIRAKYEQLLFLAPLSTSEEPL 1054 Query: 565 GQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYG 624 G+QL A +D+ T +LLLAH ++ + + + LHLA +VV+ QLL+WYG Sbjct: 1055 GRQLWAAVQAQDVATVLLLLAHARHGPLDTSVEDPQLRSPLHLAAELAHVVITQLLLWYG 1114 Query: 625 VDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 661 DV ARDA G TAL YARQA SQ C ++LLQ+GCP E Sbjct: 1115 ADVAARDAQGRTALFYARQAGSQLCADILLQHGCPGE 1151 >gi|239755300 PREDICTED: similar to centaurin, gamma-like family, member 1 [Homo sapiens] Length = 284 Score = 349 bits (895), Expect = 5e-96 Identities = 170/173 (98%), Positives = 173/173 (100%) Query: 491 SRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSKYEE 550 SRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQG+TKP+EKSTREEKERWIRSKYEE Sbjct: 112 SRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSKYEE 171 Query: 551 KLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACR 610 KLFLAPLPCT+LSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACR Sbjct: 172 KLFLAPLPCTDLSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACR 231 Query: 611 KGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV 663 KGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV Sbjct: 232 KGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV 284 Score = 39.7 bits (91), Expect = 0.009 Identities = 18/18 (100%), Positives = 18/18 (100%) Query: 155 RDADRSLSIPDEQLHSFA 172 RDADRSLSIPDEQLHSFA Sbjct: 94 RDADRSLSIPDEQLHSFA 111 >gi|239755288 PREDICTED: cyclin Y-like 2 [Homo sapiens] Length = 362 Score = 176 bits (446), Expect = 6e-44 Identities = 104/177 (58%), Positives = 118/177 (66%), Gaps = 5/177 (2%) Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTC V P S Q QG VC ESEIYEA A D +AG P+AAAV+P EVT GE Sbjct: 1 MGNILTCCVCPRASPGLHQHQGLVCHCESEIYEAAAGDLIAGVPVAAAVEPGEVTFVAGE 60 Query: 61 DLHMHHVRDREMPE--ALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQ 118 LHMHH+ +REMPE LE NPS +P+ASTIF R SQTDV E ++ VST HF+QQ Sbjct: 61 GLHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTDVQEKKKKQLCK-VSTEHFTQQ 119 Query: 119 YSLCSTIFLDDSTAIQHYLTMTIISV--TLEIPHHITQRDADRSLSIPDEQLHSFAV 173 YS CSTIFLDDS A Q +LTMT+ S I + +RDA RSL I DEQLH V Sbjct: 120 YSSCSTIFLDDSIASQPHLTMTLKSXCDLGTILSYQAKRDAHRSLGIFDEQLHPLTV 176 >gi|239749780 PREDICTED: cyclin Y-like 2 [Homo sapiens] Length = 362 Score = 176 bits (446), Expect = 6e-44 Identities = 104/177 (58%), Positives = 118/177 (66%), Gaps = 5/177 (2%) Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTC V P S Q QG VC ESEIYEA A D +AG P+AAAV+P EVT GE Sbjct: 1 MGNILTCCVCPRASPGLHQHQGLVCHCESEIYEAAAGDLIAGVPVAAAVEPGEVTFVAGE 60 Query: 61 DLHMHHVRDREMPE--ALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQ 118 LHMHH+ +REMPE LE NPS +P+ASTIF R SQTDV E ++ VST HF+QQ Sbjct: 61 GLHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTDVQEKKKKQLCK-VSTEHFTQQ 119 Query: 119 YSLCSTIFLDDSTAIQHYLTMTIISV--TLEIPHHITQRDADRSLSIPDEQLHSFAV 173 YS CSTIFLDDS A Q +LTMT+ S I + +RDA RSL I DEQLH V Sbjct: 120 YSSCSTIFLDDSIASQPHLTMTLKSXCDLGTILSYQAKRDAHRSLGIFDEQLHPLTV 176 >gi|239744040 PREDICTED: cyclin Y-like 2 [Homo sapiens] Length = 362 Score = 176 bits (446), Expect = 6e-44 Identities = 104/177 (58%), Positives = 118/177 (66%), Gaps = 5/177 (2%) Query: 1 MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGE 60 MGNILTC V P S Q QG VC ESEIYEA A D +AG P+AAAV+P EVT GE Sbjct: 1 MGNILTCCVCPRASPGLHQHQGLVCHCESEIYEAAAGDLIAGVPVAAAVEPGEVTFVAGE 60 Query: 61 DLHMHHVRDREMPE--ALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQ 118 LHMHH+ +REMPE LE NPS +P+ASTIF R SQTDV E ++ VST HF+QQ Sbjct: 61 GLHMHHICEREMPEDIPLEPNPSDHPKASTIFLRKSQTDVQEKKKKQLCK-VSTEHFTQQ 119 Query: 119 YSLCSTIFLDDSTAIQHYLTMTIISV--TLEIPHHITQRDADRSLSIPDEQLHSFAV 173 YS CSTIFLDDS A Q +LTMT+ S I + +RDA RSL I DEQLH V Sbjct: 120 YSSCSTIFLDDSIASQPHLTMTLKSXCDLGTILSYQAKRDAHRSLGIFDEQLHPLTV 176 >gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 [Homo sapiens] Length = 834 Score = 146 bits (368), Expect = 7e-35 Identities = 82/192 (42%), Positives = 114/192 (59%), Gaps = 22/192 (11%) Query: 388 FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQ----SCES-------SKSKSQLT 436 F ++S T ++ +A + + R AWVQA+Q+ I ++ + SC S S S S + Sbjct: 332 FEVLSPT-KSCMLQADSEKLRQAWVQAVQASIASAYRESPDSCYSERLDRTASPSTSSID 390 Query: 437 SQSEAM--------ALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGT 488 S ++ LQ +Q++ GN+ C DC +P+WAS+NLGVL+CIECSGIHRSLG Sbjct: 391 SATDTRERGVKGESVLQRVQSVAGNSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGV 450 Query: 489 RLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQ--GRTKPTEKSTREEKERWIRS 546 S+VRSL LD W EL K+M +GN N I+E + G KPT S+R++KE WI+ Sbjct: 451 HCSKVRSLTLDSWEPELLKLMCELGNSAVNQIYEAQCEGAGSRKPTASSSRQDKEAWIKD 510 Query: 547 KYEEKLFLAPLP 558 KY EK FL P Sbjct: 511 KYVEKKFLRKAP 522 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 2/81 (2%) Query: 561 ELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLL 620 EL G RA DL LAHG+ EVN E +G T L A G++++ + L Sbjct: 665 ELHPGLLAHRAARARDLPALAAALAHGA--EVNWADAEDEGKTPLVQAVLGGSLIVCEFL 722 Query: 621 IWYGVDVMARDAHGNTALTYA 641 + G DV RD+ G L +A Sbjct: 723 LQNGADVNQRDSRGRAPLHHA 743 >gi|187608516 centaurin, beta 2 [Homo sapiens] Length = 778 Score = 132 bits (333), Expect = 8e-31 Identities = 76/186 (40%), Positives = 111/186 (59%), Gaps = 21/186 (11%) Query: 388 FMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSC---------ESSKSKSQLTSQ 438 F +VS T ++ +A + + R AW++A+Q+ I + + +SS S L S Sbjct: 330 FEVVSPT-KSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSG 388 Query: 439 SEAM--------ALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRL 490 +E+ ALQ +Q + GNA C DC +P+WAS+NLG+ +CIECSGIHRSLG Sbjct: 389 NESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHF 448 Query: 491 SRVRSLELDDWPVELRKVMSSIGNDLANSIWEGS--SQGRTKPTEKSTREEKERWIRSKY 548 S+VRSL LD W EL K+M +GND+ N ++E + G KP + R+EKE +IR+KY Sbjct: 449 SKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKP-QPGQRQEKEAYIRAKY 507 Query: 549 EEKLFL 554 E+ F+ Sbjct: 508 VERKFV 513 Score = 38.5 bits (88), Expect = 0.020 Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 2/85 (2%) Query: 557 LPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVL 616 L L+ G QL RA+ +++L LAHG+ +VN E + T L A G++V Sbjct: 599 LDSKHLNPGLQLYRASYEKNLPKMAEALAHGA--DVNWANSEENKATPLIQAVLGGSLVT 656 Query: 617 AQLLIWYGVDVMARDAHGNTALTYA 641 + L+ G +V RD G L +A Sbjct: 657 CEFLLQNGANVNQRDVQGRGPLHHA 681 >gi|46094081 development and differentiation enhancing factor 1 [Homo sapiens] Length = 1129 Score = 130 bits (327), Expect = 4e-30 Identities = 93/293 (31%), Positives = 144/293 (49%), Gaps = 20/293 (6%) Query: 372 PHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAI---QSQILASLQSCES 428 P+A KK S N +T+HF+A ++ AW+ + + + L E Sbjct: 377 PNAEDKKSFDLISHN---------RTYHFQAEDEQDYVAWISVLTNSKEEALTMAFRGEQ 427 Query: 429 SKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGT 488 S ++ L ++A+ ++ +Q + GN C DC + P W S NLG+L CIECSGIHR +G Sbjct: 428 SAGENSLEDLTKAI-IEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGV 486 Query: 489 RLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRT-KPTEKSTREEKERWIRSK 547 +SR++SLELD + ++GN+ N I E + + KPT S ++ +I +K Sbjct: 487 HISRIQSLELDKLGTSELLLAKNVGNNSFNDIMEANLPSPSPKPTPSSDMTVRKEYITAK 546 Query: 548 YEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSR--EEVNETCGEGDGCTAL 605 Y + F T + +LL A DL I + A G E + E G+ G TAL Sbjct: 547 YVDHRFSRKTCSTSSAKLNELLEAIKSRDLLALIQVYAEGVELMEPLLEP-GQELGETAL 605 Query: 606 HLACR---KGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655 HLA R + ++ L L+ ++ + A GNT L Y S EC+ +LL+ Sbjct: 606 HLAVRTADQTSLHLVDFLVQNCGNLDKQTALGNTVLHYCSMYSKPECLKLLLR 658 >gi|7661880 centaurin beta1 [Homo sapiens] Length = 740 Score = 129 bits (325), Expect = 7e-30 Identities = 99/319 (31%), Positives = 135/319 (42%), Gaps = 70/319 (21%) Query: 391 VSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSK-------------SQLTS 437 V +T ++ +A + WV A+QS I ++ S S T Sbjct: 331 VVSTSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSAATL 390 Query: 438 QSEAMA-----------LQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSL 486 S MA + +Q++ GNA C DC P+WAS+NLGV +CI+CSGIHRSL Sbjct: 391 GSGGMARGREPGGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSL 450 Query: 487 GTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRT--KPTEKSTREEKERWI 544 G S+VRSL LD W EL K+M +GN + N I+E + KP +R+EKE WI Sbjct: 451 GVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWI 510 Query: 545 RSKYEEKLFLAPLP-----------------------------------------CTELS 563 +KY EK FL LP L Sbjct: 511 HAKYVEKKFLTKLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLGSLH 570 Query: 564 LGQQLLRATA-DEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIW 622 G L RA+ L T LAHG+ +VN G D T L A +++ + L+ Sbjct: 571 PGALLFRASGHPPSLPTMADALAHGA--DVNWVNGGQDNATPLIQATAANSLLACEFLLQ 628 Query: 623 YGVDVMARDAHGNTALTYA 641 G +V D+ G L +A Sbjct: 629 NGANVNQADSAGRGPLHHA 647 Score = 41.2 bits (95), Expect = 0.003 Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 4/86 (4%) Query: 568 LLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDV 627 L++ATA L LL +G+ ++ G G LH A G+ LA L + G D+ Sbjct: 611 LIQATAANSLLACEFLLQNGANVNQADSAGRGP----LHHATILGHTGLACLFLKRGADL 666 Query: 628 MARDAHGNTALTYARQASSQECINVL 653 ARD+ G LT A + ++ + + +L Sbjct: 667 GARDSEGRDPLTIAMETANADIVTLL 692 >gi|206725422 G protein-coupled receptor kinase interacting ArfGAP 2 isoform 5 [Homo sapiens] Length = 729 Score = 125 bits (313), Expect = 2e-28 Identities = 75/222 (33%), Positives = 114/222 (51%), Gaps = 17/222 (7%) Query: 448 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 507 + +R + C DC +P WAS+N G +C EC +HRSLG +S+VR L+ WP L + Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62 Query: 508 VMSSIGNDLANSIWEGS-------SQGRTKPT-EKSTREEKERWIRSKYEEKLFLAPLPC 559 ++ ++ N+ ANSIWE S GR K + K +IR+KY+ F+ LPC Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122 Query: 560 ------TELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 613 T L +QL + +L+T + LL+ G++ G T LH+A + G Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179 Query: 614 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655 ++ A+LL YG D +D+ G T + YARQ E L++ Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221 >gi|206725420 G protein-coupled receptor kinase interacting ArfGAP 2 isoform 6 [Homo sapiens] Length = 681 Score = 125 bits (313), Expect = 2e-28 Identities = 75/222 (33%), Positives = 114/222 (51%), Gaps = 17/222 (7%) Query: 448 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 507 + +R + C DC +P WAS+N G +C EC +HRSLG +S+VR L+ WP L + Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62 Query: 508 VMSSIGNDLANSIWEGS-------SQGRTKPT-EKSTREEKERWIRSKYEEKLFLAPLPC 559 ++ ++ N+ ANSIWE S GR K + K +IR+KY+ F+ LPC Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122 Query: 560 ------TELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 613 T L +QL + +L+T + LL+ G++ G T LH+A + G Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179 Query: 614 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655 ++ A+LL YG D +D+ G T + YARQ E L++ Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221 >gi|21237786 G protein-coupled receptor kinase interacting ArfGAP 2 isoform 3 [Homo sapiens] Length = 679 Score = 125 bits (313), Expect = 2e-28 Identities = 75/222 (33%), Positives = 114/222 (51%), Gaps = 17/222 (7%) Query: 448 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 507 + +R + C DC +P WAS+N G +C EC +HRSLG +S+VR L+ WP L + Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62 Query: 508 VMSSIGNDLANSIWEGS-------SQGRTKPT-EKSTREEKERWIRSKYEEKLFLAPLPC 559 ++ ++ N+ ANSIWE S GR K + K +IR+KY+ F+ LPC Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122 Query: 560 ------TELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 613 T L +QL + +L+T + LL+ G++ G T LH+A + G Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179 Query: 614 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655 ++ A+LL YG D +D+ G T + YARQ E L++ Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221 >gi|17149830 G protein-coupled receptor kinase interacting ArfGAP 2 isoform 1 [Homo sapiens] Length = 759 Score = 125 bits (313), Expect = 2e-28 Identities = 75/222 (33%), Positives = 114/222 (51%), Gaps = 17/222 (7%) Query: 448 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 507 + +R + C DC +P WAS+N G +C EC +HRSLG +S+VR L+ WP L + Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62 Query: 508 VMSSIGNDLANSIWEGS-------SQGRTKPT-EKSTREEKERWIRSKYEEKLFLAPLPC 559 ++ ++ N+ ANSIWE S GR K + K +IR+KY+ F+ LPC Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122 Query: 560 ------TELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 613 T L +QL + +L+T + LL+ G++ G T LH+A + G Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179 Query: 614 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655 ++ A+LL YG D +D+ G T + YARQ E L++ Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221 >gi|17149832 G protein-coupled receptor kinase interacting ArfGAP 2 isoform 2 [Homo sapiens] Length = 631 Score = 125 bits (313), Expect = 2e-28 Identities = 75/222 (33%), Positives = 114/222 (51%), Gaps = 17/222 (7%) Query: 448 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 507 + +R + C DC +P WAS+N G +C EC +HRSLG +S+VR L+ WP L + Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62 Query: 508 VMSSIGNDLANSIWEGS-------SQGRTKPT-EKSTREEKERWIRSKYEEKLFLAPLPC 559 ++ ++ N+ ANSIWE S GR K + K +IR+KY+ F+ LPC Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122 Query: 560 ------TELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 613 T L +QL + +L+T + LL+ G++ G T LH+A + G Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179 Query: 614 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655 ++ A+LL YG D +D+ G T + YARQ E L++ Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221 >gi|206725415 G protein-coupled receptor kinase interacting ArfGAP 2 isoform 4 [Homo sapiens] Length = 471 Score = 125 bits (313), Expect = 2e-28 Identities = 75/222 (33%), Positives = 114/222 (51%), Gaps = 17/222 (7%) Query: 448 QNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRK 507 + +R + C DC +P WAS+N G +C EC +HRSLG +S+VR L+ WP L + Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62 Query: 508 VMSSIGNDLANSIWEGS-------SQGRTKPT-EKSTREEKERWIRSKYEEKLFLAPLPC 559 ++ ++ N+ ANSIWE S GR K + K +IR+KY+ F+ LPC Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122 Query: 560 ------TELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGN 613 T L +QL + +L+T + LL+ G++ G T LH+A + G Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179 Query: 614 VVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655 ++ A+LL YG D +D+ G T + YARQ E L++ Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221 >gi|146231998 G protein-coupled receptor kinase interactor 1 isoform 1 [Homo sapiens] Length = 770 Score = 123 bits (308), Expect = 6e-28 Identities = 74/214 (34%), Positives = 111/214 (51%), Gaps = 17/214 (7%) Query: 456 CVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGND 515 C DC +P WAS++ GVL+C EC +HRSLG +S V+ L WP L +++ ++ ++ Sbjct: 11 CADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASN 70 Query: 516 LANSIWEGS-------SQGRTKPT-EKSTREEKERWIRSKYEEKLFLAPLPC------TE 561 ANSIWE S GR K + K +IR+KY+ F+ LPC T Sbjct: 71 GANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTA 130 Query: 562 LSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLI 621 L +QL + +L+T + LL+ G++ G T LH+A + G + A+LL+ Sbjct: 131 KDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGTTPLHVAAKAGQTLQAELLV 187 Query: 622 WYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655 YG D + D +G T + YARQA E L++ Sbjct: 188 VYGADPGSPDVNGRTPIDYARQAGHHELAERLVE 221 >gi|41393573 G protein-coupled receptor kinase interactor 1 isoform 2 [Homo sapiens] Length = 761 Score = 123 bits (308), Expect = 6e-28 Identities = 74/214 (34%), Positives = 111/214 (51%), Gaps = 17/214 (7%) Query: 456 CVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGND 515 C DC +P WAS++ GVL+C EC +HRSLG +S V+ L WP L +++ ++ ++ Sbjct: 11 CADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASN 70 Query: 516 LANSIWEGS-------SQGRTKPT-EKSTREEKERWIRSKYEEKLFLAPLPC------TE 561 ANSIWE S GR K + K +IR+KY+ F+ LPC T Sbjct: 71 GANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTA 130 Query: 562 LSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLI 621 L +QL + +L+T + LL+ G++ G T LH+A + G + A+LL+ Sbjct: 131 KDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGTTPLHVAAKAGQTLQAELLV 187 Query: 622 WYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655 YG D + D +G T + YARQA E L++ Sbjct: 188 VYGADPGSPDVNGRTPIDYARQAGHHELAERLVE 221 >gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 isoform b [Homo sapiens] Length = 894 Score = 117 bits (292), Expect = 4e-26 Identities = 88/279 (31%), Positives = 135/279 (48%), Gaps = 24/279 (8%) Query: 396 QTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEA-----------MAL 444 +T+HF+A E +AWV +Q+ +L S + + S A + + Sbjct: 361 RTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAGPGSWGSAGHDGEPHDLTKLLI 420 Query: 445 QSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD-DWPV 503 +++ GN+ C DC +P W S NLGVL CI+CSG+HR LG R SR++SL LD P Sbjct: 421 AEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPS 480 Query: 504 ELRKVMSSIGNDLANSIWEGS--SQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTE 561 EL + ++GN N + E S G KP+ +S + +I +KY E F CT Sbjct: 481 ELLLAL-NMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFAR--RCTP 537 Query: 562 LSLGQQLLRATADEDLQTAILLLAHGS--REEVNETCGEGDGCTALHLACRKGN---VVL 616 Q+L A + DL + + A+G + + + LHLA + N + L Sbjct: 538 EP--QRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPL 595 Query: 617 AQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQ 655 +I G + A+ A GNTAL YA + +C+ +LL+ Sbjct: 596 VDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLK 634 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.128 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,304,628 Number of Sequences: 37866 Number of extensions: 1211423 Number of successful extensions: 5372 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 336 Number of HSP's successfully gapped in prelim test: 74 Number of HSP's that attempted gapping in prelim test: 3821 Number of HSP's gapped (non-prelim): 1435 length of query: 663 length of database: 18,247,518 effective HSP length: 109 effective length of query: 554 effective length of database: 14,120,124 effective search space: 7822548696 effective search space used: 7822548696 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.