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Search of human proteins with 117938759
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117938759 GNAS complex locus XLas [Homo sapiens]
(1037 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117938759 GNAS complex locus XLas [Homo sapiens] 2117 0.0
gi|4504047 GNAS complex locus GNASL [Homo sapiens] 746 0.0
gi|117938762 GNAS complex locus isoform f [Homo sapiens] 742 0.0
gi|18426900 GNAS complex locus GNASS [Homo sapiens] 707 0.0
gi|117938765 GNAS complex locus isoform g [Homo sapiens] 705 0.0
gi|33695153 guanine nucleotide binding protein (G protein), alph... 598 e-170
gi|4504043 guanine nucleotide binding protein (G protein), alpha... 597 e-170
gi|215272301 guanine nucleotide binding protein (G protein), alp... 597 e-170
gi|162461738 guanine nucleotide binding protein, alpha activatin... 262 1e-69
gi|156139155 guanine nucleotide binding protein, alpha transduci... 261 2e-69
gi|10567816 guanine nucleotide binding protein, alpha activating... 261 3e-69
gi|20330805 guanine nucleotide binding protein, alpha transducin... 255 1e-67
gi|4504041 guanine nucleotide binding protein (G protein), alpha... 255 2e-67
gi|5729850 guanine nucleotide binding protein (G protein), alpha... 251 2e-66
gi|33946324 guanine nucleotide binding protein (G protein), alph... 249 7e-66
gi|22027522 rod-type transducin alpha subunit [Homo sapiens] 249 1e-65
gi|22027520 rod-type transducin alpha subunit [Homo sapiens] 249 1e-65
gi|40254462 guanine nucleotide binding protein (G protein), q po... 248 3e-65
gi|115511049 guanine nucleotide binding protein (G protein), alp... 246 1e-64
gi|4758444 G alpha 14 [Homo sapiens] 244 4e-64
gi|4504051 guanine nucleotide binding protein, alpha z polypepti... 236 8e-62
gi|156104883 guanine nucleotide binding protein (G protein), alp... 228 2e-59
gi|24111250 guanine nucleotide binding protein (G protein), alph... 226 7e-59
gi|42476111 guanine nucleotide binding protein (G protein) alpha... 226 1e-58
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 98 4e-20
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 91 4e-18
gi|163965366 nascent polypeptide-associated complex alpha subuni... 91 7e-18
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 87 1e-16
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 86 2e-16
gi|150170670 piccolo isoform 2 [Homo sapiens] 84 5e-16
>gi|117938759 GNAS complex locus XLas [Homo sapiens]
Length = 1037
Score = 2117 bits (5485), Expect = 0.0
Identities = 1037/1037 (100%), Positives = 1037/1037 (100%)
Query: 1 MGVRNCLYGNNMSGQRDIPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIP 60
MGVRNCLYGNNMSGQRDIPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIP
Sbjct: 1 MGVRNCLYGNNMSGQRDIPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIP 60
Query: 61 VENDGEACGPPEVSRPNFQVLNPAFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQ 120
VENDGEACGPPEVSRPNFQVLNPAFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQ
Sbjct: 61 VENDGEACGPPEVSRPNFQVLNPAFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQ 120
Query: 121 PGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQ 180
PGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQ
Sbjct: 121 PGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQ 180
Query: 181 VPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPP 240
VPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPP
Sbjct: 181 VPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPP 240
Query: 241 GLSRVIAQVDGSSQFAAVAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSP 300
GLSRVIAQVDGSSQFAAVAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSP
Sbjct: 241 GLSRVIAQVDGSSQFAAVAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSP 300
Query: 301 WMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAE 360
WMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAE
Sbjct: 301 WMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAE 360
Query: 361 MEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADP 420
MEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADP
Sbjct: 361 MEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADP 420
Query: 421 DSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAA 480
DSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAA
Sbjct: 421 DSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAA 480
Query: 481 ETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSPEIQAADP 540
ETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSPEIQAADP
Sbjct: 481 ETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSPEIQAADP 540
Query: 541 PTPRPTRASAWRGKSESSRGRRVYYDEGVASSDDDSSGDESDDGTSGCLRWFQHRRNRRR 600
PTPRPTRASAWRGKSESSRGRRVYYDEGVASSDDDSSGDESDDGTSGCLRWFQHRRNRRR
Sbjct: 541 PTPRPTRASAWRGKSESSRGRRVYYDEGVASSDDDSSGDESDDGTSGCLRWFQHRRNRRR 600
Query: 601 RKPQRNLLRNFLVQAFGGCFGRSESPQPKASRSLKVKKVPLAEKRRQMRKEALEKRAQKR 660
RKPQRNLLRNFLVQAFGGCFGRSESPQPKASRSLKVKKVPLAEKRRQMRKEALEKRAQKR
Sbjct: 601 RKPQRNLLRNFLVQAFGGCFGRSESPQPKASRSLKVKKVPLAEKRRQMRKEALEKRAQKR 660
Query: 661 AEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDP 720
AEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDP
Sbjct: 661 AEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDP 720
Query: 721 QAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNV 780
QAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNV
Sbjct: 721 QAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNV 780
Query: 781 PDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDL 840
PDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDL
Sbjct: 781 PDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDL 840
Query: 841 LRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVI 900
LRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVI
Sbjct: 841 LRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVI 900
Query: 901 REDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFAR 960
REDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFAR
Sbjct: 901 REDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFAR 960
Query: 961 YTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFN 1020
YTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFN
Sbjct: 961 YTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFN 1020
Query: 1021 DCRDIIQRMHLRQYELL 1037
DCRDIIQRMHLRQYELL
Sbjct: 1021 DCRDIIQRMHLRQYELL 1037
>gi|4504047 GNAS complex locus GNASL [Homo sapiens]
Length = 394
Score = 746 bits (1927), Expect = 0.0
Identities = 365/384 (95%), Positives = 376/384 (97%)
Query: 654 EKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNG 713
++R +++A+++ +K I+KQLQ +K Y THRLLLLGAGESGKSTIVKQMRILHVNGFNG
Sbjct: 11 DQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNG 70
Query: 714 EGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDY 773
EGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDY
Sbjct: 71 EGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDY 130
Query: 774 ILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADY 833
ILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADY
Sbjct: 131 ILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADY 190
Query: 834 VPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS 893
VPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS
Sbjct: 191 VPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS 250
Query: 894 SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIED 953
SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIED
Sbjct: 251 SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIED 310
Query: 954 YFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTE 1013
YFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTE
Sbjct: 311 YFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTE 370
Query: 1014 NIRRVFNDCRDIIQRMHLRQYELL 1037
NIRRVFNDCRDIIQRMHLRQYELL
Sbjct: 371 NIRRVFNDCRDIIQRMHLRQYELL 394
>gi|117938762 GNAS complex locus isoform f [Homo sapiens]
Length = 395
Score = 742 bits (1915), Expect = 0.0
Identities = 365/385 (94%), Positives = 376/385 (97%), Gaps = 1/385 (0%)
Query: 654 EKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNG 713
++R +++A+++ +K I+KQLQ +K Y THRLLLLGAGESGKSTIVKQMRILHVNGFNG
Sbjct: 11 DQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNG 70
Query: 714 EGGEEDPQAARSNSDG-EKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVD 772
EGGEEDPQAARSNSDG EKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVD
Sbjct: 71 EGGEEDPQAARSNSDGSEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVD 130
Query: 773 YILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQAD 832
YILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQAD
Sbjct: 131 YILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQAD 190
Query: 833 YVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVA 892
YVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVA
Sbjct: 191 YVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVA 250
Query: 893 SSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIE 952
SSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIE
Sbjct: 251 SSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIE 310
Query: 953 DYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDT 1012
DYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDT
Sbjct: 311 DYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDT 370
Query: 1013 ENIRRVFNDCRDIIQRMHLRQYELL 1037
ENIRRVFNDCRDIIQRMHLRQYELL
Sbjct: 371 ENIRRVFNDCRDIIQRMHLRQYELL 395
>gi|18426900 GNAS complex locus GNASS [Homo sapiens]
Length = 380
Score = 707 bits (1824), Expect = 0.0
Identities = 350/384 (91%), Positives = 361/384 (94%), Gaps = 14/384 (3%)
Query: 654 EKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNG 713
++R +++A+++ +K I+KQLQ +K Y THRLLLLGAGESGKSTIVKQMRILHVNGFNG
Sbjct: 11 DQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNG 70
Query: 714 EGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDY 773
D EKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDY
Sbjct: 71 --------------DSEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDY 116
Query: 774 ILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADY 833
ILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADY
Sbjct: 117 ILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADY 176
Query: 834 VPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS 893
VPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS
Sbjct: 177 VPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS 236
Query: 894 SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIED 953
SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIED
Sbjct: 237 SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIED 296
Query: 954 YFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTE 1013
YFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTE
Sbjct: 297 YFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTE 356
Query: 1014 NIRRVFNDCRDIIQRMHLRQYELL 1037
NIRRVFNDCRDIIQRMHLRQYELL
Sbjct: 357 NIRRVFNDCRDIIQRMHLRQYELL 380
>gi|117938765 GNAS complex locus isoform g [Homo sapiens]
Length = 379
Score = 705 bits (1819), Expect = 0.0
Identities = 349/384 (90%), Positives = 361/384 (94%), Gaps = 15/384 (3%)
Query: 654 EKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNG 713
++R +++A+++ +K I+KQLQ +K Y THRLLLLGAGESGKSTIVKQMRILHVNGFNG
Sbjct: 11 DQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNG 70
Query: 714 EGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDY 773
+ EKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDY
Sbjct: 71 D---------------EKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDY 115
Query: 774 ILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADY 833
ILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADY
Sbjct: 116 ILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADY 175
Query: 834 VPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS 893
VPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS
Sbjct: 176 VPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS 235
Query: 894 SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIED 953
SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIED
Sbjct: 236 SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIED 295
Query: 954 YFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTE 1013
YFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTE
Sbjct: 296 YFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTE 355
Query: 1014 NIRRVFNDCRDIIQRMHLRQYELL 1037
NIRRVFNDCRDIIQRMHLRQYELL
Sbjct: 356 NIRRVFNDCRDIIQRMHLRQYELL 379
>gi|33695153 guanine nucleotide binding protein (G protein), alpha
activating activity polypeptide, olfactory type isoform 1
[Homo sapiens]
Length = 458
Score = 598 bits (1541), Expect = e-170
Identities = 295/417 (70%), Positives = 342/417 (82%), Gaps = 17/417 (4%)
Query: 621 GRSESPQPKASRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGY 680
G +PKA + K K+ + + R+ A E+ A K A +K S+ ID+ L+D+K
Sbjct: 59 GSPACARPKADKP-KEKRQRTEQLSAEEREAAKEREAVKEA-RKVSRGIDRMLRDQKRDL 116
Query: 681 MCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKN 740
THRLLLLGAGESGKSTIVKQMRILHVNGFN E EK K+ DI+
Sbjct: 117 QQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPE---------------EKKQKILDIRK 161
Query: 741 NLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDE 800
N+K+AI TIV+AMS ++PPV LANPENQFR DYI S+ + DF++ EF++H K LW+DE
Sbjct: 162 NVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDE 221
Query: 801 GVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKV 860
GV+AC+ERSNEYQLIDCAQYFL++ID + DY P+DQDLLRCRVLTSGIFET+FQVDKV
Sbjct: 222 GVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKV 281
Query: 861 NFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIW 920
NFHMFDVGGQRDERRKWIQCFNDVTAII+V A SSYNMVIREDN TNRL+E+L+LF+SIW
Sbjct: 282 NFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIW 341
Query: 921 NNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRA 980
NNRWLRTIS+ILFLNKQD+LAEKVLAGKSKIEDYFPE+A YT PEDATP+ GEDP+VTRA
Sbjct: 342 NNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRA 401
Query: 981 KYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL 1037
K+FIRD FLRISTA+GDG+HYCYPHFTCAVDTENIRRVFNDCRDIIQRMHL+QYELL
Sbjct: 402 KFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL 458
>gi|4504043 guanine nucleotide binding protein (G protein), alpha
activating activity polypeptide, olfactory type isoform 2
[Homo sapiens]
Length = 381
Score = 597 bits (1538), Expect = e-170
Identities = 285/388 (73%), Positives = 330/388 (85%), Gaps = 15/388 (3%)
Query: 650 KEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVN 709
K ++ ++ ++ +K I+KQLQ E++ Y THRLLLLGAGESGKSTIVKQMRILHVN
Sbjct: 9 KTTEDQGVDEKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVN 68
Query: 710 GFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQF 769
GFN E EK K+ DI+ N+K+AI TIV+AMS ++PPV LANPENQF
Sbjct: 69 GFNPE---------------EKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQF 113
Query: 770 RVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIK 829
R DYI S+ + DF++ EF++H K LW+DEGV+AC+ERSNEYQLIDCAQYFL++ID +
Sbjct: 114 RSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVS 173
Query: 830 QADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIF 889
DY P+DQDLLRCRVLTSGIFET+FQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAII+
Sbjct: 174 LVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIY 233
Query: 890 VVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKS 949
V A SSYNMVIREDN TNRL+E+L+LF+SIWNNRWLRTIS+ILFLNKQD+LAEKVLAGKS
Sbjct: 234 VAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKS 293
Query: 950 KIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCA 1009
KIEDYFPE+A YT PEDATP+ GEDP+VTRAK+FIRD FLRISTA+GDG+HYCYPHFTCA
Sbjct: 294 KIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCA 353
Query: 1010 VDTENIRRVFNDCRDIIQRMHLRQYELL 1037
VDTENIRRVFNDCRDIIQRMHL+QYELL
Sbjct: 354 VDTENIRRVFNDCRDIIQRMHLKQYELL 381
>gi|215272301 guanine nucleotide binding protein (G protein), alpha
activating activity polypeptide, olfactory type isoform 2
[Homo sapiens]
Length = 381
Score = 597 bits (1538), Expect = e-170
Identities = 285/388 (73%), Positives = 330/388 (85%), Gaps = 15/388 (3%)
Query: 650 KEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVN 709
K ++ ++ ++ +K I+KQLQ E++ Y THRLLLLGAGESGKSTIVKQMRILHVN
Sbjct: 9 KTTEDQGVDEKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVN 68
Query: 710 GFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQF 769
GFN E EK K+ DI+ N+K+AI TIV+AMS ++PPV LANPENQF
Sbjct: 69 GFNPE---------------EKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQF 113
Query: 770 RVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIK 829
R DYI S+ + DF++ EF++H K LW+DEGV+AC+ERSNEYQLIDCAQYFL++ID +
Sbjct: 114 RSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVS 173
Query: 830 QADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIF 889
DY P+DQDLLRCRVLTSGIFET+FQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAII+
Sbjct: 174 LVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIY 233
Query: 890 VVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKS 949
V A SSYNMVIREDN TNRL+E+L+LF+SIWNNRWLRTIS+ILFLNKQD+LAEKVLAGKS
Sbjct: 234 VAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKS 293
Query: 950 KIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCA 1009
KIEDYFPE+A YT PEDATP+ GEDP+VTRAK+FIRD FLRISTA+GDG+HYCYPHFTCA
Sbjct: 294 KIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCA 353
Query: 1010 VDTENIRRVFNDCRDIIQRMHLRQYELL 1037
VDTENIRRVFNDCRDIIQRMHL+QYELL
Sbjct: 354 VDTENIRRVFNDCRDIIQRMHLKQYELL 381
>gi|162461738 guanine nucleotide binding protein, alpha activating
polypeptide O isoform b [Homo sapiens]
Length = 354
Score = 262 bits (669), Expect = 1e-69
Identities = 157/378 (41%), Positives = 218/378 (57%), Gaps = 37/378 (9%)
Query: 657 AQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGG 716
A++RA +RSK I+K L+++ + +LLLLGAGESGKSTIVKQM+I+H +GF+GE
Sbjct: 7 AEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDV 66
Query: 717 EEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILS 776
++ SN+ +++ IV AM L +E + E + +
Sbjct: 67 KQYKPVVYSNTI---------------QSLAAIVRAMDTL--GIEYGDKERKADAKMVCD 109
Query: 777 VMN-VPDFD-FPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYV 834
V++ + D + F E LW D G++ C+ RS EYQL D A+Y+LD +D I ADY
Sbjct: 110 VVSRMEDTEPFSAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQ 169
Query: 835 PSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASS 894
P++QD+LR RV T+GI ET F ++F +FDVGGQR ER+KWI CF DVTAIIF VA S
Sbjct: 170 PTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALS 229
Query: 895 SYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDY 954
Y+ V+ ED TNR+ E+L LF SI NN+W S+ILFLNK+D+ EK+ KS +
Sbjct: 230 GYDQVLHEDETTNRMHESLKLFDSICNNKWFTDTSIILFLNKKDIFEEKI--KKSPLTIC 287
Query: 955 FPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTEN 1014
FPE YT P T A +I+ ++ + + Y H TCA DT N
Sbjct: 288 FPE---YTGPS----------AFTEAVAYIQAQY---ESKNKSAHKEIYTHVTCATDTNN 331
Query: 1015 IRRVFNDCRDIIQRMHLR 1032
I+ VF+ D+I +LR
Sbjct: 332 IQFVFDAVTDVIIAKNLR 349
>gi|156139155 guanine nucleotide binding protein, alpha transducing 3
[Homo sapiens]
Length = 354
Score = 261 bits (668), Expect = 2e-69
Identities = 153/377 (40%), Positives = 224/377 (59%), Gaps = 35/377 (9%)
Query: 657 AQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGG 716
++ + KRSK ++K+LQ++ T +LLLLGAGESGKSTIVKQM+I+H NG+
Sbjct: 7 SESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGY----- 61
Query: 717 EEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILS 776
S+ E I +N ++I IV AM+ L ++ NP + + +
Sbjct: 62 ----------SEQECMEFKAVIYSNTLQSILAIVKAMTTL--GIDYVNPRSAEDQRQLYA 109
Query: 777 VMN-VPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVP 835
+ N + D P+ E K LW D G++AC+ER++EYQL D A Y+L+ +D I + YVP
Sbjct: 110 MANTLEDGGMTPQLAEVIKRLWRDPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVP 169
Query: 836 SDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSS 895
++QD+L RV T+GI ET+F ++F MFDVGGQR ER+KWI CF VT IIF A S+
Sbjct: 170 NEQDVLHSRVKTTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSA 229
Query: 896 YNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYF 955
Y+MV+ ED + NR+ E+L+LF SI N+++ T S++LFLNK+D+ EKV K + F
Sbjct: 230 YDMVLVEDEEVNRMHESLHLFNSICNHKYFSTTSIVLFLNKKDIFQEKVT--KVHLSICF 287
Query: 956 PEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENI 1015
PE+ T ED A +I+++FL ++ D Y H TCA DT+N+
Sbjct: 288 PEYTGPNTFED-------------AGNYIKNQFLDLNLKKEDKE--IYSHMTCATDTQNV 332
Query: 1016 RRVFNDCRDIIQRMHLR 1032
+ VF+ DII + +L+
Sbjct: 333 KFVFDAVTDIIIKENLK 349
>gi|10567816 guanine nucleotide binding protein, alpha activating
polypeptide O isoform a [Homo sapiens]
Length = 354
Score = 261 bits (666), Expect = 3e-69
Identities = 160/378 (42%), Positives = 219/378 (57%), Gaps = 37/378 (9%)
Query: 657 AQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGG 716
A++RA +RSK I+K L+++ + +LLLLGAGESGKSTIVKQM+I+H +GF+GE
Sbjct: 7 AEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDV 66
Query: 717 EEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILS 776
++ SN+ +++ IV AM L +E + E + +
Sbjct: 67 KQYKPVVYSNTI---------------QSLAAIVRAMDTL--GIEYGDKERKADAKMVCD 109
Query: 777 VMN-VPDFD-FPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYV 834
V++ + D + F E LW D G++ C+ RS EYQL D A+Y+LD +D I ADY
Sbjct: 110 VVSRMEDTEPFSAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQ 169
Query: 835 PSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASS 894
P++QD+LR RV T+GI ET F ++F +FDVGGQR ER+KWI CF DVTAIIF VA S
Sbjct: 170 PTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALS 229
Query: 895 SYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDY 954
Y+ V+ ED TNR+ E+L LF SI NN++ S+ILFLNK+DL EK+ KS +
Sbjct: 230 GYDQVLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKI--KKSPLTIC 287
Query: 955 FPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTEN 1014
FPE+ T EDA +I+ +F S + YC H TCA DT N
Sbjct: 288 FPEYTGPNTYEDAAA-------------YIQAQF-ESKNRSPNKEIYC--HMTCATDTNN 331
Query: 1015 IRRVFNDCRDIIQRMHLR 1032
I+ VF+ DII +LR
Sbjct: 332 IQVVFDAVTDIIIANNLR 349
>gi|20330805 guanine nucleotide binding protein, alpha transducing
activity polypeptide 2 [Homo sapiens]
Length = 354
Score = 255 bits (652), Expect = 1e-67
Identities = 151/377 (40%), Positives = 225/377 (59%), Gaps = 35/377 (9%)
Query: 657 AQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGG 716
A+ + KRSK ++K+LQ++ T +LLLLGAGESGKSTIVKQM+I+H +G++ E
Sbjct: 7 AEDKELAKRSKELEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDGYSPEEC 66
Query: 717 EEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILS 776
E I N+ ++I I+ AM+ L ++ A P + +
Sbjct: 67 LEFKAI---------------IYGNVLQSILAIIRAMTTL--GIDYAEPSCADDGRQLNN 109
Query: 777 VMN-VPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVP 835
+ + + + PPE E + LW+D GV+AC+ER+ EYQL D A Y+L++++ I +Y+P
Sbjct: 110 LADSIEEGTMPPELVEVIRRLWKDGGVQACFERAAEYQLNDSASYYLNQLERITDPEYLP 169
Query: 836 SDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSS 895
S+QD+LR RV T+GI ETKF V +NF MFDVGGQR ER+KWI CF VT IIF A S+
Sbjct: 170 SEQDVLRSRVKTTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSA 229
Query: 896 YNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYF 955
Y+MV+ ED++ NR+ E+L+LF SI N+++ S++LFLNK+DL EK+ K + F
Sbjct: 230 YDMVLVEDDEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKI--KKVHLSICF 287
Query: 956 PEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENI 1015
PE+ + +D A +I+ +FL ++ Y H TCA DT+N+
Sbjct: 288 PEYDGNNSYDD-------------AGNYIKSQFLDLNMRKDVKE--IYSHMTCATDTQNV 332
Query: 1016 RRVFNDCRDIIQRMHLR 1032
+ VF+ DII + +L+
Sbjct: 333 KFVFDAVTDIIIKENLK 349
>gi|4504041 guanine nucleotide binding protein (G protein), alpha
inhibiting activity polypeptide 2 [Homo sapiens]
Length = 355
Score = 255 bits (651), Expect = 2e-67
Identities = 152/378 (40%), Positives = 222/378 (58%), Gaps = 36/378 (9%)
Query: 657 AQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGG 716
A+ +A +RSK+IDK L+++ +LLLLGAGESGKSTIVKQM+I+H +G++
Sbjct: 7 AEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYS---- 62
Query: 717 EEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPE--NQFRVDYI 774
EE+ + R+ + +N ++I IV AM NL ++ A+P + R +
Sbjct: 63 EEECRQYRAV-----------VYSNTIQSIMAIVKAMGNL--QIDFADPSRADDARQLFA 109
Query: 775 LSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYV 834
LS P + + LW D GV+AC+ RS EYQL D A Y+L+ ++ I Q+DY+
Sbjct: 110 LSCTAEEQGVLPDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYI 169
Query: 835 PSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASS 894
P+ QD+LR RV T+GI ET F ++F MFDVGGQR ER+KWI CF VTAIIF VA S
Sbjct: 170 PTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALS 229
Query: 895 SYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDY 954
+Y++V+ ED + NR+ E++ LF SI NN+W S+ILFLNK+DL EK+ S +
Sbjct: 230 AYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIT--HSPLTIC 287
Query: 955 FPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTEN 1014
FPE+ ++A +I+ +F ++ Y HFTCA DT+N
Sbjct: 288 FPEYTGANKYDEAAS-------------YIQSKFEDLNKRKDTKE--IYTHFTCATDTKN 332
Query: 1015 IRRVFNDCRDIIQRMHLR 1032
++ VF+ D+I + +L+
Sbjct: 333 VQFVFDAVTDVIIKNNLK 350
>gi|5729850 guanine nucleotide binding protein (G protein), alpha
inhibiting activity polypeptide 3 [Homo sapiens]
Length = 354
Score = 251 bits (642), Expect = 2e-66
Identities = 151/377 (40%), Positives = 217/377 (57%), Gaps = 33/377 (8%)
Query: 657 AQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGG 716
A+ +A +RSK+ID+ L+++ +LLLLGAGESGKSTIVKQM+I+H +G++
Sbjct: 7 AEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYS---- 62
Query: 717 EEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILS 776
D K KV N ++ I I+ AM L A + R ++L+
Sbjct: 63 ----------EDECKQYKVVVYSNTIQSII-AIIRAMGRLKIDFGEAARADDARQLFVLA 111
Query: 777 VMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPS 836
+ + PE K LW D GV+AC+ RS EYQL D A Y+L+ +D I Q++Y+P+
Sbjct: 112 G-SAEEGVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPT 170
Query: 837 DQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSY 896
QD+LR RV T+GI ET F + F MFDVGGQR ER+KWI CF VTAIIF VA S Y
Sbjct: 171 QQDVLRTRVKTTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDY 230
Query: 897 NMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFP 956
++V+ ED + NR+ E++ LF SI NN+W S+ILFLNK+DL EK+ +S + +P
Sbjct: 231 DLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKI--KRSPLTICYP 288
Query: 957 EFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIR 1016
E+ T E+A +I+ +F ++ Y HFTCA DT+N++
Sbjct: 289 EYTGSNTYEEAAA-------------YIQCQFEDLNRRKDTKE--IYTHFTCATDTKNVQ 333
Query: 1017 RVFNDCRDIIQRMHLRQ 1033
VF+ D+I + +L++
Sbjct: 334 FVFDAVTDVIIKNNLKE 350
>gi|33946324 guanine nucleotide binding protein (G protein), alpha
inhibiting activity polypeptide 1 [Homo sapiens]
Length = 354
Score = 249 bits (637), Expect = 7e-66
Identities = 150/376 (39%), Positives = 216/376 (57%), Gaps = 33/376 (8%)
Query: 657 AQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGG 716
A+ +A +RSK+ID+ L+++ +LLLLGAGESGKSTIVKQM+I+H G++ E
Sbjct: 7 AEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEEC 66
Query: 717 EEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILS 776
++ SN+ ++I I+ AM L + + R ++L+
Sbjct: 67 KQYKAVVYSNTI---------------QSIIAIIRAMGRLKIDFGDSARADDARQLFVLA 111
Query: 777 VMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPS 836
F E K LW+D GV+AC+ RS EYQL D A Y+L+ +D I Q +Y+P+
Sbjct: 112 GAAEEGF-MTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPT 170
Query: 837 DQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSY 896
QD+LR RV T+GI ET F ++F MFDVGGQR ER+KWI CF VTAIIF VA S Y
Sbjct: 171 QQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDY 230
Query: 897 NMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFP 956
++V+ ED + NR+ E++ LF SI NN+W S+ILFLNK+DL EK+ KS + +P
Sbjct: 231 DLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKI--KKSPLTICYP 288
Query: 957 EFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIR 1016
E+A T E+A +I+ +F ++ Y HFTCA DT+N++
Sbjct: 289 EYAGSNTYEEAAA-------------YIQCQFEDLNKRKDTKE--IYTHFTCATDTKNVQ 333
Query: 1017 RVFNDCRDIIQRMHLR 1032
VF+ D+I + +L+
Sbjct: 334 FVFDAVTDVIIKNNLK 349
>gi|22027522 rod-type transducin alpha subunit [Homo sapiens]
Length = 350
Score = 249 bits (635), Expect = 1e-65
Identities = 145/373 (38%), Positives = 223/373 (59%), Gaps = 35/373 (9%)
Query: 661 AEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDP 720
AE+K S+ ++K+L+++ T +LLLLGAGESGKSTIVKQM+I+H +G++ E
Sbjct: 7 AEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLE------ 60
Query: 721 QAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMN- 779
E + I N ++I IV AM+ L ++ + Q ++ + +
Sbjct: 61 ---------ECLEFIAIIYGNTLQSILAIVRAMTTL--NIQYGDSARQDDARKLMHMADT 109
Query: 780 VPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQD 839
+ + P E + + LW+D G++AC+ER++EYQL D A Y+L ++ + YVP++QD
Sbjct: 110 IEEGTMPKEMSDIIQRLWKDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQD 169
Query: 840 LLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMV 899
+LR RV T+GI ET+F +NF MFDVGGQR ER+KWI CF VT IIF+ A S+Y+MV
Sbjct: 170 VLRSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMV 229
Query: 900 IREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFA 959
+ ED++ NR+ E+L+LF SI N+R+ T S++LFLNK+D+ EK+ K+ + FP++
Sbjct: 230 LVEDDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFFEKI--KKAHLSICFPDYD 287
Query: 960 RYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVF 1019
T ED A +I+ +FL ++ Y H TCA DT+N++ VF
Sbjct: 288 GPNTYED-------------AGNYIKVQFLELNMRRDVKE--IYSHMTCATDTQNVKFVF 332
Query: 1020 NDCRDIIQRMHLR 1032
+ DII + +L+
Sbjct: 333 DAVTDIIIKENLK 345
>gi|22027520 rod-type transducin alpha subunit [Homo sapiens]
Length = 350
Score = 249 bits (635), Expect = 1e-65
Identities = 145/373 (38%), Positives = 223/373 (59%), Gaps = 35/373 (9%)
Query: 661 AEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDP 720
AE+K S+ ++K+L+++ T +LLLLGAGESGKSTIVKQM+I+H +G++ E
Sbjct: 7 AEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLE------ 60
Query: 721 QAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMN- 779
E + I N ++I IV AM+ L ++ + Q ++ + +
Sbjct: 61 ---------ECLEFIAIIYGNTLQSILAIVRAMTTL--NIQYGDSARQDDARKLMHMADT 109
Query: 780 VPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQD 839
+ + P E + + LW+D G++AC+ER++EYQL D A Y+L ++ + YVP++QD
Sbjct: 110 IEEGTMPKEMSDIIQRLWKDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQD 169
Query: 840 LLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMV 899
+LR RV T+GI ET+F +NF MFDVGGQR ER+KWI CF VT IIF+ A S+Y+MV
Sbjct: 170 VLRSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMV 229
Query: 900 IREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFA 959
+ ED++ NR+ E+L+LF SI N+R+ T S++LFLNK+D+ EK+ K+ + FP++
Sbjct: 230 LVEDDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFFEKI--KKAHLSICFPDYD 287
Query: 960 RYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVF 1019
T ED A +I+ +FL ++ Y H TCA DT+N++ VF
Sbjct: 288 GPNTYED-------------AGNYIKVQFLELNMRRDVKE--IYSHMTCATDTQNVKFVF 332
Query: 1020 NDCRDIIQRMHLR 1032
+ DII + +L+
Sbjct: 333 DAVTDIIIKENLK 345
>gi|40254462 guanine nucleotide binding protein (G protein), q
polypeptide [Homo sapiens]
Length = 359
Score = 248 bits (632), Expect = 3e-65
Identities = 143/369 (38%), Positives = 212/369 (57%), Gaps = 34/369 (9%)
Query: 669 IDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSD 728
I++QL+ +K +LLLLG GESGKST +KQMRI+H +G+ SD
Sbjct: 25 IERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGY---------------SD 69
Query: 729 GEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPE 788
+K + + N+ A++ ++ AM L P + + + ++ + V V F+ P
Sbjct: 70 EDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENP-- 127
Query: 789 FYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTS 848
+ + K+LW D G++ CY+R EYQL D +Y+L+ +D + Y+P+ QD+LR RV T+
Sbjct: 128 YVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPTT 187
Query: 849 GIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNR 908
GI E F + V F M DVGGQR ERRKWI CF +VT+I+F+VA S Y+ V+ E + NR
Sbjct: 188 GIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENR 247
Query: 909 LQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDAT 968
++E+ LF++I W + SVILFLNK+DLL EK++ S + DYFPE+
Sbjct: 248 MEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIM--YSHLVDYFPEY---------- 295
Query: 969 PEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQR 1028
G A+ FI F+ ++ D Y HFTCA DTENIR VF +D I +
Sbjct: 296 --DGPQRDAQAAREFILKMFVDLNP---DSDKIIYSHFTCATDTENIRFVFAAVKDTILQ 350
Query: 1029 MHLRQYELL 1037
++L++Y L+
Sbjct: 351 LNLKEYNLV 359
>gi|115511049 guanine nucleotide binding protein (G protein), alpha 11
(Gq class) [Homo sapiens]
Length = 359
Score = 246 bits (627), Expect = 1e-64
Identities = 148/378 (39%), Positives = 212/378 (56%), Gaps = 34/378 (8%)
Query: 660 RAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEED 719
+ K+ + I+KQL+ +K +LLLLG GESGKST +KQMRI+H G++ E
Sbjct: 16 KESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEE----- 70
Query: 720 PQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMN 779
D TK+ + N+ A++ ++ AM L + +N+ I V
Sbjct: 71 --------DKRGFTKL--VYQNIFTAMQAMIRAMETL--KILYKYEQNKANALLIREVDV 118
Query: 780 VPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQD 839
F ++ K LWED G++ CY+R EYQL D A+Y+L +D I Y+P+ QD
Sbjct: 119 EKVTTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQD 178
Query: 840 LLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMV 899
+LR RV T+GI E F ++ + F M DVGGQR ERRKWI CF +VT+I+F+VA S Y+ V
Sbjct: 179 VLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQV 238
Query: 900 IREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFA 959
+ E + NR++E+ LF++I W + SVILFLNK+DLL +K+L S + DYFPEF
Sbjct: 239 LVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKIL--YSHLVDYFPEF- 295
Query: 960 RYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVF 1019
G A+ FI F+ ++ D Y HFTCA DTENIR VF
Sbjct: 296 -----------DGPQRDAQAAREFILKMFVDLNP---DSDKIIYSHFTCATDTENIRFVF 341
Query: 1020 NDCRDIIQRMHLRQYELL 1037
+D I +++L++Y L+
Sbjct: 342 AAVKDTILQLNLKEYNLV 359
>gi|4758444 G alpha 14 [Homo sapiens]
Length = 355
Score = 244 bits (622), Expect = 4e-64
Identities = 151/382 (39%), Positives = 217/382 (56%), Gaps = 36/382 (9%)
Query: 657 AQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGG 716
A+++ ++ S I++QL+ +K +LLLLG GESGKST +KQMRI+H +G++ E
Sbjct: 9 AEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDE-- 66
Query: 717 EEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILS 776
D + TK+ + N+ A++ ++ AM L ++ +N+ I
Sbjct: 67 -----------DRKGFTKL--VYQNIFTAMQAMIRAMDTL--RIQYVCEQNKENAQIIRE 111
Query: 777 VMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPS 836
V E E K LW+D G++ CY+R EYQL D A+Y+L ID I +VP+
Sbjct: 112 VEVDKVSMLSREQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPT 171
Query: 837 DQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSY 896
QD+LR RV T+GI E F ++ + F M DVGGQR ERRKWI CF VT+IIF+VA S Y
Sbjct: 172 QQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEY 231
Query: 897 NMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFP 956
+ V+ E + NR++E+ LFK+I W SVILFLNK+DLL EK++ S + YFP
Sbjct: 232 DQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIM--YSHLISYFP 289
Query: 957 EFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRI-STASGDGRHYCYPHFTCAVDTENI 1015
E YT P+ +D R RD L++ + D Y HFTCA DT+NI
Sbjct: 290 E---YTGPK-------QDVRAA------RDFILKLYQDQNPDKEKVIYSHFTCATDTDNI 333
Query: 1016 RRVFNDCRDIIQRMHLRQYELL 1037
R VF +D I +++LR++ L+
Sbjct: 334 RFVFAAVKDTILQLNLREFNLV 355
>gi|4504051 guanine nucleotide binding protein, alpha z polypeptide
[Homo sapiens]
Length = 355
Score = 236 bits (602), Expect = 8e-62
Identities = 142/378 (37%), Positives = 210/378 (55%), Gaps = 36/378 (9%)
Query: 657 AQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGG 716
++++ +RS+ ID+ L+ E +LLLLG SGKSTIVKQM+I+H GFN E
Sbjct: 7 SEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEAC 66
Query: 717 EEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILS 776
+E I N +++ I+ A++ L ++ NP+ + + +
Sbjct: 67 KEYKPL---------------IIYNAIDSLTRIIRALAAL--RIDFHNPDRAYDAVQLFA 109
Query: 777 VMNVPDF--DFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYV 834
+ + + PE + LW D G +AC+ RS+EY L D A Y+L+ ++ I ADY+
Sbjct: 110 LTGPAESKGEITPELLGVMRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYI 169
Query: 835 PSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASS 894
P+ +D+LR R +T+GI E KF ++ F M DVGGQR ER+KWI CF VTAIIF V S
Sbjct: 170 PTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELS 229
Query: 895 SYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDY 954
Y++ + EDNQT+R+ E+L LF SI NN W S+ILFLNK+DLLAEK+ + +
Sbjct: 230 GYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKI--RRIPLTIC 287
Query: 955 FPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTEN 1014
FPE+ T E+A +I+ +F ++ Y HFTCA DT N
Sbjct: 288 FPEYKGQNTYEEAA-------------VYIQRQFEDLN--RNKETKEIYSHFTCATDTSN 332
Query: 1015 IRRVFNDCRDIIQRMHLR 1032
I+ VF+ D+I + +L+
Sbjct: 333 IQFVFDAVTDVIIQNNLK 350
>gi|156104883 guanine nucleotide binding protein (G protein), alpha 15
(Gq class) [Homo sapiens]
Length = 374
Score = 228 bits (581), Expect = 2e-59
Identities = 139/393 (35%), Positives = 214/393 (54%), Gaps = 44/393 (11%)
Query: 654 EKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNG 713
+++A R +++ ++++ +Q + ++ G + +LLLLG GESGKST +KQMRI+H G++
Sbjct: 17 DEKAAARVDQEINRILLEQKKQDR-GEL---KLLLLGPGESGKSTFIKQMRIIHGAGYS- 71
Query: 714 EGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDY 773
EE+ + R + N+ ++ ++ AM L P + PE++
Sbjct: 72 ---EEERKGFRPL-----------VYQNIFVSMRAMIEAMERLQIP--FSRPESKHHASL 115
Query: 774 ILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADY 833
++S F + + LW D G+RA YER E+ L+D A Y+L ++ I + Y
Sbjct: 116 VMSQDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGY 175
Query: 834 VPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS 893
VP+ QD+LR R+ T+GI E F V K N + DVGGQ+ ER+KWI CF +V A+I++ +
Sbjct: 176 VPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASL 235
Query: 894 SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIED 953
S Y+ + E+NQ NR++E+L LF +I W ++ SVILFLNK D+L EK+ S +
Sbjct: 236 SEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKI--PTSHLAT 293
Query: 954 YFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDG---------RHYCYP 1004
YFP F G AK FI D + R+ T DG +
Sbjct: 294 YFPSF------------QGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFS 341
Query: 1005 HFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL 1037
H+TCA DT+NIR+VF D RD + +L + LL
Sbjct: 342 HYTCATDTQNIRKVFKDVRDSVLARYLDEINLL 374
>gi|24111250 guanine nucleotide binding protein (G protein), alpha 13
[Homo sapiens]
Length = 377
Score = 226 bits (577), Expect = 7e-59
Identities = 143/381 (37%), Positives = 207/381 (54%), Gaps = 37/381 (9%)
Query: 662 EKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQ 721
++++SK IDK L EK ++LLLGAGESGKST +KQMRI+H F+ EE
Sbjct: 27 QQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRP 86
Query: 722 AARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNL-VPPVELANPEN-----QFRVDYIL 775
I +N+ + + +V A L +P + +N ++ F +
Sbjct: 87 T---------------IYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPM 131
Query: 776 SVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVP 835
+ + + ++ +ALW D G++ Y+R E+QL + +YFLD +D + + DY+P
Sbjct: 132 AAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIP 191
Query: 836 SDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSS 895
S QD+L R T GI E F++ V F M DVGGQR ER++W +CF+ VT+I+F+V+SS
Sbjct: 192 SQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSE 251
Query: 896 YNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYF 955
++ V+ ED TNRL E+LN+F++I NNR +S+ILFLNK DLL EKV I+DYF
Sbjct: 252 FDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQI--VSIKDYF 309
Query: 956 PEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENI 1015
EF DP R E R + + Y HFT A++TENI
Sbjct: 310 LEFE-------------GDPHCLRDVQKFLVECFR-NKRRDQQQKPLYHHFTTAINTENI 355
Query: 1016 RRVFNDCRDIIQRMHLRQYEL 1036
R VF D +D I +L+Q L
Sbjct: 356 RLVFRDVKDTILHDNLKQLML 376
>gi|42476111 guanine nucleotide binding protein (G protein) alpha 12
[Homo sapiens]
Length = 381
Score = 226 bits (575), Expect = 1e-58
Identities = 147/409 (35%), Positives = 217/409 (53%), Gaps = 38/409 (9%)
Query: 632 RSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGA 691
R+L +P + R+ R +R ++RS+ ID L E+ ++LLLGA
Sbjct: 6 RTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGA 65
Query: 692 GESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVA 751
GESGKST +KQMRI+H G E D +A D I +N+ + +V
Sbjct: 66 GESGKSTFLKQMRIIH-------GREFDQKALLEFRD--------TIFDNILKGSRVLVD 110
Query: 752 AMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYE----HAKALWEDEGVRACYE 807
A L P + + EN+ ++++ N P ++ ALW D G+R +
Sbjct: 111 ARDKLGIPWQYS--ENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFS 168
Query: 808 RSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDV 867
R +E+QL + +YFLD +D I Q +Y PS QD+L R T GI E F + K+ F M DV
Sbjct: 169 RRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDV 228
Query: 868 GGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRT 927
GGQR +R+KW QCF+ +T+I+F+V+SS Y+ V+ ED +TNRL E++N+F++I NN+
Sbjct: 229 GGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFN 288
Query: 928 ISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDE 987
+S+ILFLNK DLL EKV I+ +FP+F P ED + + F R
Sbjct: 289 VSIILFLNKMDLLVEKVKT--VSIKKHFPDFR-------GDPHRLEDVQRYLVQCFDRKR 339
Query: 988 FLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYEL 1036
R + HFT A+DTEN+R VF+ +D I + +L+ L
Sbjct: 340 RNRSKP--------LFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML 380
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 98.2 bits (243), Expect = 4e-20
Identities = 170/632 (26%), Positives = 202/632 (31%), Gaps = 115/632 (18%)
Query: 33 APGAAAPGAGPSPAEEMETEPPHNEPIPVENDGE--------------ACGPPEVSRPNF 78
APG A P + P P P N GE GP V P
Sbjct: 402 APGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPP- 460
Query: 79 QVLNPAFREA--GAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGP 136
PA E GA G P P E P GF P + P G + GP
Sbjct: 461 ---GPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGF-PGADGVAGPKGPAGERGSPGP 516
Query: 137 ALMEPGAFSGARPGLGGY-----------SPPPE--EAMPFEFDQPAQRGCSQLLLQVPD 183
A + RPG G SP P+ P Q + G P
Sbjct: 517 AGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPG--------PP 568
Query: 184 LAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLS 243
PG G AGV G P + A P KAG R G PP P DGE P P
Sbjct: 569 GPPGARGQAGVMGFPGPKGAAGEPGKAGER-GVPGPPGAVGPAGKDGEAGAQGPPGP--- 624
Query: 244 RVIAQVDGSSQFAAVAASSAVRLTPAANAPP--------LWVPGAIGSPSQEAVRPPSNF 295
A G A S + P PP VPG +G+P R F
Sbjct: 625 ---AGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGF 681
Query: 296 TGSSPWMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKR--ERAERPP 353
G + GPP G P G + P N + A G P GAP + + P
Sbjct: 682 PGE---RGVQGPPGPAG--PRGANGAPGNDGAKGDA--GAP----GAPGSQGAPGLQGMP 730
Query: 354 VEEEAAEMEG----AADAAEGGKVPSPG----------YGSPAAGAASADTAARAAPAAP 399
E AA + G DA G SPG G P A D + P+ P
Sbjct: 731 GERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGD-KGESGPSGP 789
Query: 400 ADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADP-DSGAAPDA-PADPDSGA 457
A P +GA D G P P FA P + P A +P D+GA DA P P A
Sbjct: 790 AGP-TGARGAPGDRG-EPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPA 847
Query: 458 APDAP----ADPDAGAAPEAPAAPAAA--ETRAAHVAPAAP--DAGAPTAPAASATRAAQ 509
P P P A A + P A A V P P +AG P P + +
Sbjct: 848 GPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGK 907
Query: 510 VRRAASAAPASGARRKIHLRPPSPEIQAAD------------PPTPRPTRASAWRG--KS 555
R + A R + PP P A + P TP P + RG
Sbjct: 908 GPRGETGP----AGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGL 963
Query: 556 ESSRGRRVYYDEGVASSDDDSSGDESDDGTSG 587
RG R + S + G G G
Sbjct: 964 PGQRGERGFPGLPGPSGEPGKQGPSGASGERG 995
Score = 84.3 bits (207), Expect = 5e-16
Identities = 151/612 (24%), Positives = 188/612 (30%), Gaps = 76/612 (12%)
Query: 14 GQRDIPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEAC--GPP 71
G+ P G + + + PG P A E P P DGEA GPP
Sbjct: 563 GRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPP 622
Query: 72 EVSRPNFQVLNPAFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGL 131
+ P E G G P + +P A P G +PG GV L
Sbjct: 623 GPAGPA--------GERGEQGPAGSPGFQGLPGPAGPPGEAG------KPG-EQGVPGDL 667
Query: 132 EAFGPALMEPGAFSGAR-----PGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQVPDLAP 186
A GP SGAR PG G PP A P + ++ P AP
Sbjct: 668 GAPGP--------SGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPG-AP 718
Query: 187 GGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVI 246
G GA G+ G P E A P G RG P + P + G PPG +
Sbjct: 719 GSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAP 778
Query: 247 AQVDGSSQFAAVAASSAVRLTPAANAPP--------LWVPGAIGSPSQEAVRPPSNFTGS 298
G S + A + R P P PGA G P + + G
Sbjct: 779 GD-KGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGD 837
Query: 299 S---PWMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVE 355
+ +GPP IG+ A PP A P P PP
Sbjct: 838 AGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGP 897
Query: 356 EEAAEMEG-------AADAAEGGKVPSPGYGSPAA--GAASADTAARAAPAAPADPD--- 403
A EG A G+V PG PA G+ AD A AP P
Sbjct: 898 PGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPA-GAPGTPGPQGIAG 956
Query: 404 ----SGATPEDPDSGTAPADPDSGAFAADPDSGAA----PAAPADPDSGAAPDAPADPDS 455
G + + G SG SGA+ P P P A P P +
Sbjct: 957 QRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGP--PGESGR 1014
Query: 456 GAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAAS 515
AP A P +P A AP AP A P PA + + A
Sbjct: 1015 EGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGP 1074
Query: 516 AAPASGARRKIHLRPPSPEIQAADPPTPRPTRASAWRGKSESSRGRRVYYDEGVASSDDD 575
A P + R P A P PR + +G R +
Sbjct: 1075 AGPVG----PVGARGP------AGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPG 1124
Query: 576 SSGDESDDGTSG 587
S G++ G SG
Sbjct: 1125 SPGEQGPSGASG 1136
Score = 69.7 bits (169), Expect = 1e-11
Identities = 123/509 (24%), Positives = 146/509 (28%), Gaps = 71/509 (13%)
Query: 35 GAAAPGA-GPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAFREAGAHGS 93
G + PG GPS + P P + G P S P G G
Sbjct: 174 GISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGP-----------MGPRGP 222
Query: 94 YSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFG-PALMEPGAFSG---ARP 149
PP + EA +P P P P G G P + FSG A+
Sbjct: 223 PGPPGKNGDDGEAGKPGR----PGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKG 278
Query: 150 GLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQVPDLAPGGPGAAGVPGAPPEEPQALRPAK 209
G P E P E P Q G P PG G G PG
Sbjct: 279 DAGPAGPKGEPGSPGENGAPGQMG--------PRGLPGERGRPGAPGPAGARGNDGATGA 330
Query: 210 AGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSAVRLTPA 269
AG G P P + +G P G S V G A ++ P
Sbjct: 331 AGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRG-SEGPQGVRGEPGPPGPAGAAGPAGNPG 389
Query: 270 ANAPP-----LWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGS-----APAGVD 319
A+ P PG G+P R PS G GPP G+ AP
Sbjct: 390 ADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPG------GPPGPKGNSGEPGAPGSKG 443
Query: 320 DTPVNMDSPPIALDGPPIKVSGAPDKRERAER-------PPVEEEAAEMEG--AADAAEG 370
DT + P+ + GPP + R E PP E G AD G
Sbjct: 444 DTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAG 503
Query: 371 GKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPD 430
K P+ GSP + +P P P +P P PD
Sbjct: 504 PKGPAGERGSPGPAGP------KGSPGEAGRPGEAGLPGAKGLTGSPGSPG-------PD 550
Query: 431 SGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPA 490
P PA D P P A P A A V PA
Sbjct: 551 GKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPA 610
Query: 491 APD--AGA--PTAPAASATRAAQVRRAAS 515
D AGA P PA A + A S
Sbjct: 611 GKDGEAGAQGPPGPAGPAGERGEQGPAGS 639
Score = 59.7 bits (143), Expect = 1e-08
Identities = 128/539 (23%), Positives = 167/539 (30%), Gaps = 82/539 (15%)
Query: 52 EPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAFREAGAHGSYSPPPEEAMPFEAEQPSL 111
E P E PV DG P + + G G PP + +P QP L
Sbjct: 85 EVPEGECCPVCPDGSE-SPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIP---GQPGL 140
Query: 112 GGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQ 171
G PG P GP PG PGLGG P + + +D+ +
Sbjct: 141 PG------PPGPP----------GP----PGP-----PGLGGNFAPQ---LSYGYDEKST 172
Query: 172 RGCSQLLLQVPDLA------PGGPGAAGVPGAP--PEEPQALRPAKAGSRGGYSPPPEET 223
G S P PG PG G G P P EP A P G RG PP +
Sbjct: 173 GGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGP--MGPRGPPGPPGKNG 230
Query: 224 MPFELDGEGFGDDSPPPGLS-----------------RVIAQVDGSSQFAAVAASSAVRL 266
E G + PPG R + +DG+ A A
Sbjct: 231 DDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPG 290
Query: 267 TPAAN-AP----PLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDT 321
+P N AP P +PG G P P+ G+ +GPP G PAG
Sbjct: 291 SPGENGAPGQMGPRGLPGERGRPGAPG---PAGARGNDGATGAAGPPGPTG--PAGPPGF 345
Query: 322 PVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAEMEGAADAAEGGKVPSPGYGSP 381
P + + A GP + R E P A A+G G+P
Sbjct: 346 PGAVGAKGEA--GPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAP 403
Query: 382 AAGAASADTAARAAPAAPADPDSGATPE--DPDSGTAPADPDSGAFAADPDSGAAPAAPA 439
A AR P+ P P P+ + G + D+GA +P P
Sbjct: 404 GIAGAPGFPGAR-GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGA-KGEPGPVGVQGPPG 461
Query: 440 DPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTA 499
A +P P P + + P A A + +P P
Sbjct: 462 PAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKG 521
Query: 500 PAASATRAAQV----RRAASAAPAS-GARRKIHLRPPSPEIQAADPPTPRPTRASAWRG 553
A R + + + +P S G K PP P Q P P P A G
Sbjct: 522 SPGEAGRPGEAGLPGAKGLTGSPGSPGPDGK--TGPPGPAGQDGRPGPPGPPGARGQAG 578
Score = 30.4 bits (67), Expect = 9.0
Identities = 57/207 (27%), Positives = 70/207 (33%), Gaps = 13/207 (6%)
Query: 12 MSGQRDIPPEIGEQPEQ--PPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACG 69
++GQR + G++ E+ P L P GPS A E PP P+ G A
Sbjct: 954 IAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASG-ERGPPG----PMGPPGLAGP 1008
Query: 70 PPEVSRPNFQVLNPAFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHA 129
P E R A G GS + A P G P P P+G
Sbjct: 1009 PGESGREGAP---GAEGSPGRDGSPGAKGDRGETGPAGPPGAPGA-PGAPGPVGPAGKSG 1064
Query: 130 GLEAFGPA-LMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLL-LQVPDLAPG 187
GPA P GAR G P ++ E +G LQ P PG
Sbjct: 1065 DRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPG 1124
Query: 188 GPGAAGVPGAPPEEPQALRPAKAGSRG 214
PG G GA P AG+ G
Sbjct: 1125 SPGEQGPSGASGPAGPRGPPGSAGAPG 1151
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 91.3 bits (225), Expect = 4e-18
Identities = 147/577 (25%), Positives = 195/577 (33%), Gaps = 83/577 (14%)
Query: 26 PEQPPLEAPGAAA------PGAGPSPAEEMETEPP--HNEPIPVENDGEACGPPEVSRPN 77
PE P P +A P + P + E PP + P PV + G A G
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130
Query: 78 FQVLNPAFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFP-----SGVHAGLE 132
+ L + E A G + P+ + + G P P +G GL
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 190
Query: 133 AFGPALMEPGAFSGARPGLGGYSP-------PPEEAMPFE---FDQPAQRGCSQLLLQVP 182
P+ G R + S P P +PA R S +
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250
Query: 183 DLAPGGPGAAGVPGAP--PEEP-----QALRPAKAGSRGGYSPPPEETMPF--ELDGEGF 233
A GP A G P AP P +P QALRP + +PP ++ P L
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV------TPPRKDAAPALGPLSSSPL 304
Query: 234 GDDSPPPGLSR----VIAQVDGSSQFAAVAASSAVRLTPAANAPPLWVPGAIGSPSQEAV 289
SP L + SS A+ P+ +APP ++ +
Sbjct: 305 ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPP-----SLQTLPSPPA 359
Query: 290 RPPSNFTGSSPWMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERA 349
PPS T S + + S P TP P +AL PP++ +P
Sbjct: 360 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL--PPLQAPPSPPAS--- 414
Query: 350 ERPPVEEEAAEMEGAADA-------AEGGKVPSPGYGSPAAGAASADTAARAAPAAPADP 402
PP+ A A +A A PSP +P + AS + A P + A P
Sbjct: 415 --PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472
Query: 403 DSGATP-EDPDSGTAPADPDSGAFAADPDSG----AAPAAPADPDSGAAPDAPADPDSGA 457
A P + P S PA P A P AAP AP A A P A
Sbjct: 473 SLAAPPLQVPPS--PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 530
Query: 458 APDAPADPDAGAAPEAPAA-----PAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRR 512
P PA G AP +P+A P A A AAP P +P AS T A RR
Sbjct: 531 LPSPPAS-FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP-RR 588
Query: 513 AASAAP---ASGARRKIHLRPPSPEIQAADPPTPRPT 546
+ P SG R + L P P PP+ P+
Sbjct: 589 PPTPGPDTSVSGPRLTLALAPGPP-----PPPSRSPS 620
Score = 68.2 bits (165), Expect = 4e-11
Identities = 132/569 (23%), Positives = 186/569 (32%), Gaps = 109/569 (19%)
Query: 30 PLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAFREAG 89
PL +P + P A +P P + + +A PP+V+ P PA
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGL------QALRPPQVTPPRKDAA-PALGPLS 300
Query: 90 AHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARP 149
+ +P P A+ +A PTL P P + P + P + S
Sbjct: 301 SSPLATPSPSAALQSQAP--------PTL--PATPHSSSLTCQLATPLPLAPPSPS---- 346
Query: 150 GLGGYSPPPEEAMPFEFDQPAQRGCSQL---LLQVPDLAPGGPGAAGVPGAPPEEPQALR 206
+PP + +P P + + L LQ P + + PP+ P AL
Sbjct: 347 -----APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL- 400
Query: 207 PAKAGSRGGYSPPPEETMPFELDGEGFGDDSPP--PGLSRVIAQVDGSSQFAAVAASSAV 264
+ PP + P SPP P LS + + AV A
Sbjct: 401 ----------ALPPLQAPP-----------SPPASPPLSPLATPSPQAPNALAVHLLQAP 439
Query: 265 RLTPAANAPPLWVPGA--IGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDTP 322
P + PP+ P + P + PPS S + PP S P TP
Sbjct: 440 FSPPPS--PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 497
Query: 323 VNMDSPPIALDGPPIKVSGAPDKRERA-ERPPVE---EEAAEMEGAADAAEGGKVPSPGY 378
PP+A PP++++ P + A PP++ A G A + +P
Sbjct: 498 PPQAPPPLA--APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 555
Query: 379 GSPAAGAASADTAA--RAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPA 436
+P A A + P+ PA P A P G PD+ AP
Sbjct: 556 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG-----PDTSVSGPRLTLALAPG 610
Query: 437 APADPD---------------SGAAPDAPAD-------PDSGAAPDAPADPDAGAAPEAP 474
P P S +A P + P+ GAA P D + A A
Sbjct: 611 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 670
Query: 475 AAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRA---ASAAPASGARRKIHLRP- 530
+ A A AP AP P SA + SA PA GA L P
Sbjct: 671 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA-----LDPG 725
Query: 531 PSPEIQAADPPTPRPTRASAWRGKSESSR 559
PSP +A+A G SSR
Sbjct: 726 PSPGTSGG--------KAAAGAGAGASSR 746
Score = 63.2 bits (152), Expect = 1e-09
Identities = 103/422 (24%), Positives = 137/422 (32%), Gaps = 72/422 (17%)
Query: 19 PPEIGEQPEQPPLEAPGAAAPGA------------GPSPAEEMETEPPHNEPIPVENDGE 66
PP P PL P AP A PSP + PP + P+
Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 467
Query: 67 ACGPPEVSRPNFQV-----LNPAFREAGAHGSYSPPPEEAMPFEAEQPSLGG----FWPT 117
+ PP ++ P QV +P + +PPP A P + +P P
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 527
Query: 118 LEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQL 177
L+ P G F P+ P + P PP A P P+ L
Sbjct: 528 LQALPSPPASFPGQAPFSPSASLPMSPLATPPP----QAPPVLAAPLLQVPPSPPASPTL 583
Query: 178 L------LQVPDLAPGGPG-----AAGVPGAPPEEPQAL--RPAKAGSRGGYSPPPEETM 224
PD + GP A G P P P + P AG + PEE
Sbjct: 584 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 643
Query: 225 PFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSAVRLTPAANAPPLWVPGAIGSP 284
++ EG SPPP ++ AA ++ R APPL GA G+P
Sbjct: 644 GYDSGPEGGAAASPPP-----------DAELAACHPAAWSR----GPAPPLAFRGAPGAP 688
Query: 285 SQEAVRPPSNFTGSSPWM----EISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVS 340
PP+ GS+ + E GP AP +D P S A G S
Sbjct: 689 ---LPWPPATGPGSADGLCTIYETEGPE-SATPAPGALDPGPSPGTSGGKAAAGAGAGAS 744
Query: 341 GAPDKRERAERPPVEEEAAE----------MEGAADAAEGGKVPSPGYGSPAAGAASADT 390
K+ R P+ A + AA+ A GG PG G+ G
Sbjct: 745 SRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPG-GAEGGGVTGGAR 803
Query: 391 AA 392
AA
Sbjct: 804 AA 805
Score = 62.0 bits (149), Expect = 3e-09
Identities = 89/326 (27%), Positives = 116/326 (35%), Gaps = 55/326 (16%)
Query: 259 AASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAP--- 315
A + A TPAA AP L P GSP RPP T ++ + + G +G P
Sbjct: 8 AKAGAAARTPAARAPGLLTPRPPGSP-----RPPPPVTPAA--LRVLGAAGAVGRKPLAE 60
Query: 316 --AGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAEMEGAADAAEGGKV 373
G+ + P A P + +G R A RPP E A G V
Sbjct: 61 RAGGIGGATI----PESAPRAGPTRSAGT-SSRNPASRPPASGR-GERAPPAKNTSPGPV 114
Query: 374 PSPGYGS-------------------PAAGAASADTAARAAPAAPADPD-SGATPEDPDS 413
SPG S A + + R+A +A A D SG TP P
Sbjct: 115 SSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 174
Query: 414 GTAPADPDSGAFAA--DPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAP 471
A +G P A P P + + A + +P A P AG
Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 234
Query: 472 EAPAAPAAAETRAAHVAPA--APDA-GAPTAPA---------ASATRAAQVR-RAASAAP 518
+ PA+ + + + +PA P A G P APA A R QV AAP
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP 294
Query: 519 ASGARRKIHLRPPSPE--IQAADPPT 542
A G L PSP +Q+ PPT
Sbjct: 295 ALGPLSSSPLATPSPSAALQSQAPPT 320
Score = 36.6 bits (83), Expect = 0.13
Identities = 44/145 (30%), Positives = 56/145 (38%), Gaps = 16/145 (11%)
Query: 431 SGAAPAAPADPDSGAAPDAPADPDSGAAPDAPAD----PDAGAAPEAPAAPAAAETRAAH 486
+GAA PA G P P PA AGA P A A A
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69
Query: 487 VAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSPEIQAADPPTPRPT 546
+ +AP AG PT A +++ R AS PASG + PP+ + P P
Sbjct: 70 IPESAPRAG-PTRSAGTSS-----RNPASRPPASGRGER---APPAK--NTSPGPVSSPG 118
Query: 547 RAS-AWRGKSESSRGRRVYYDEGVA 570
RAS R +G R+ +E VA
Sbjct: 119 RASGTTRPGPLGQKGLRISAEETVA 143
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 90.5 bits (223), Expect = 7e-18
Identities = 140/553 (25%), Positives = 178/553 (32%), Gaps = 68/553 (12%)
Query: 19 PPEIGEQPEQPPLEAPGAAAPGAG-PSPAEEMETEPPHNEPIP-VENDGEACGPPEVSRP 76
PP P PL P A PSP T P P G P P
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099
Query: 77 NFQVLNPAFREAGAHGSYSPPPEEAMPFE--AEQPSLGGFWPTLEQPGFPSGVHAGLEAF 134
+ PA G + PP + P A PS G T G P+
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT-------- 1151
Query: 135 GPALMEPGAFSG-ARPGLGGYSPPPEEAMPFE---FDQPAQRGCSQLLLQVPDLAPGGPG 190
PA P G A P G P P P+ +G P GG
Sbjct: 1152 -PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1210
Query: 191 AAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVD 250
GAP P A P+ G SP T P G + PP
Sbjct: 1211 TPSPKGAPTT-PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP---------- 1259
Query: 251 GSSQFAAVAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTG--SSPWMEISGPP 308
A + TP + L P G+P+ V PPS G +SP PP
Sbjct: 1260 ------PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPP 1313
Query: 309 FEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAEMEGAADAA 368
+P G TP PP PP +P P + +G
Sbjct: 1314 AATPPSPKGSPGTP-----PPKGAPTPPAVTPPSPKGT-----PTLPATTPSSKGGPTTP 1363
Query: 369 EGGKVPSPGYGSPA--AGAASADTAARAAPAAPA---DPDSGAT-PEDPDSGTAPADPDS 422
+ P+P +P+ G A + + PA P+ DP S A P P APA P +
Sbjct: 1364 SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK--APATPVT 1421
Query: 423 GAFAADPDSG-AAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGA----APEAPAAP 477
AA P G P A AP A A P + DP A +P+ P AP
Sbjct: 1422 REGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP 1481
Query: 478 AAAETRAA-HVAPAAP-DAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSPEI 535
T ++ APA P GAPT PA + +V PA+ + R+ + P + +
Sbjct: 1482 KQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEV-------PATPSSRRDPIAPTATLL 1534
Query: 536 QAADPPTPRPTRA 548
P T P A
Sbjct: 1535 SKKTPATLAPKEA 1547
Score = 88.6 bits (218), Expect = 3e-17
Identities = 144/581 (24%), Positives = 186/581 (32%), Gaps = 84/581 (14%)
Query: 29 PPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAFREA 88
PP P + G P + T P P P G PP P PA
Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTTPAATPPSP---KGGLATPPPKGAPT----TPAATPP 1157
Query: 89 GAHGSYSPPPEEAMPFE--AEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSG 146
G + PP + P A PS G T G P+ PA P G
Sbjct: 1158 SPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTT---------PAATPPSPKGG 1208
Query: 147 -ARPGLGGYSPPPEEAMPFE---FDQPAQRGCSQLLLQVPDLAPGGPGAAGVPGAPPEEP 202
A P G P P P+ +G P GGP GAP P
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPT--P 1266
Query: 203 QALRPAKAGSRGGYSPPPEETMPFEL-----DGEGFGDDSPPPGLSRVIAQVDGSSQFAA 257
A P +GG + PP + P +G SPP G A S + +
Sbjct: 1267 PAATPPSL--KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSP 1324
Query: 258 VAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWM-EISGPPFEIGSAPA 316
TP A PP G+P+ A P S ++P E PP S
Sbjct: 1325 GTPPPKGAPTPPAVTPP----SPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380
Query: 317 GVDDTPVNMDSPPI--ALDGPPIKVSGAPDKRERAERPPVEEEAAEMEGAADAAEGGKVP 374
G TP + P + G P + P ++A PV E GAA ++G P
Sbjct: 1381 GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTRE-----GAATPSKGDLTP 1435
Query: 375 SPGYGSPAAGAASADTAARAAPAAPADPDSGATPE-DPDSGTAPADPDSGAFAADPDSGA 433
P + A A +A + PA P+ P P S P P A ++ P
Sbjct: 1436 -PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKK-- 1492
Query: 434 APAAPADPDSGAAP--------DAPADPDSGAAPDAPAD------------------PDA 467
APA PA + P + PA P S P AP P A
Sbjct: 1493 APATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPA 1552
Query: 468 GAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPA------SG 521
P PA + A P++ +A +P A S + A + PA
Sbjct: 1553 MTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE 1612
Query: 522 ARRKIHLRPPSPEIQAADP-----PTPRPTRASAWRGKSES 557
A + PPSPE A P PT P S+ + S
Sbjct: 1613 APTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTS 1653
Score = 86.3 bits (212), Expect = 1e-16
Identities = 144/567 (25%), Positives = 174/567 (30%), Gaps = 109/567 (19%)
Query: 30 PLEAPGAAAPGAGP-------SPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLN 82
P E P AP P SP + T P P G A PP + P+
Sbjct: 896 PKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKG-APTPPAATPPS----- 949
Query: 83 PAFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPG 142
P A ++P P A P PS G T G P+ PA P
Sbjct: 950 PKGGPATPSPKWAPTPPAATP-----PSPKGGPATPSPKGAPTP---------PAATPPS 995
Query: 143 AFSG-ARPGLGGYSPPPEEAMPFEFDQPAQ----RGCSQLLLQVPDLAPGGPGAAGVPGA 197
G A P G PP P PA +G S P G P A +P
Sbjct: 996 PKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKG 1055
Query: 198 PPEEPQALRPAKAG-----SRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGS 252
P P A P+ G S G PP T P SP G
Sbjct: 1056 APTTPAATLPSPKGGPATPSLKGAPTPPAATPP-----------SPKGG----------- 1093
Query: 253 SQFAAVAASSAVRLTPAANAPP----LWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPP 308
A + + PAA P L P G+P+ A PPS G ++ PP
Sbjct: 1094 ---PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG------LATPP 1144
Query: 309 FEIGSAPAGVDDTPV-NMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAEMEGAADA 367
P G TP SP L PP K GAP P A A
Sbjct: 1145 ------PKGAPTTPAATPPSPKGGLATPPPK--GAPTTPAATPPSPKGGLATPSPKGAPT 1196
Query: 368 AEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAA 427
PSP G A T A P +P + +P+ + A P A
Sbjct: 1197 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPA 1256
Query: 428 DPDSGAAPAAPA------------DPDSGAAPDA---PADPDSGAA---PDAPADPDAGA 469
P AP PA P GA A P P G A P P A
Sbjct: 1257 TPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAAT 1316
Query: 470 APEAPAAPAAAETRAAHVAPAA---PDAGAPTAPAAS-ATRAAQVRRAASAAPASGARRK 525
P +P + A PA G PT PA + +++ ++ P A
Sbjct: 1317 PPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATP 1376
Query: 526 IH-----LRPPSPEIQAADP-PTPRPT 546
H + PPSP+ A P P PT
Sbjct: 1377 SHKGGPAMTPPSPKRGPAIPSPKGDPT 1403
Score = 81.3 bits (199), Expect = 4e-15
Identities = 123/466 (26%), Positives = 156/466 (33%), Gaps = 61/466 (13%)
Query: 131 LEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFE-FDQPAQRGCSQLLLQVPDLAPGGP 189
LE+ PA + P G SP E + + P + G L VP + P
Sbjct: 650 LESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCP 709
Query: 190 GAAGVPGA-PPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQ 248
A P L P S S PP T P +G S ++ +
Sbjct: 710 VAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKE 769
Query: 249 VDGSSQFAAVAASSAVRLTPAANAP-PLWVPGAIGSPSQEAVRPPSNFTGSSPWMEI--- 304
A+ ASS LT A++P PL V S S + RPP+ + P I
Sbjct: 770 CPTEDSGASATASSKGTLTYLADSPSPLGV-----SVSPQTKRPPTKKGSAGPDTPIGNL 824
Query: 305 SGP--PFEIGSAPA------GVDDTPVNMDSP-PIALDGPPIKVSGAPDKRERAERPPVE 355
S P P E P G D+P SP P + G P + P + PP E
Sbjct: 825 SSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKE 884
Query: 356 EEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPA---APADPD-------SG 405
+ EG P+P + +S+ ARA PA PA P
Sbjct: 885 TPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPA 944
Query: 406 ATPEDPDSGTA--------------PADPDSGAFAADPDSGAAPAAPADPDSGAAPDAPA 451
ATP P G A P P G P P A P P P+
Sbjct: 945 ATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPS 1004
Query: 452 DPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPA---APDA-----GAPTAPAAS 503
P P A P +P A P A T A P+ +P A GAPT PAA+
Sbjct: 1005 -PKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT 1063
Query: 504 ATRAAQVRRAASAAPA-SGARRKIHLRPPSPEIQAADPPTPRPTRA 548
+ A P+ GA PPSP+ P TP P A
Sbjct: 1064 LPSP----KGGPATPSLKGAPTPPAATPPSPK---GGPATPSPKGA 1102
Score = 74.3 bits (181), Expect = 5e-13
Identities = 119/423 (28%), Positives = 147/423 (34%), Gaps = 88/423 (20%)
Query: 185 APGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEET-------MPFELDGEGFGDDS 237
+P P G P P A+ P S G + PP+ET +PF +G +
Sbjct: 855 SPTPPSPKGAP-----TPSAVTPL---SPKGVTLPPKETPTPSVVNLPFPKEGPA----T 902
Query: 238 PPPGLSRVIAQVDGSSQFAAVAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTG 297
P P + ++ S + A R TPA P P G+P+ A PPS G
Sbjct: 903 PAPKQAPALSMTSSSPKKA--------RATPAPKGIPA-SPSPKGAPTPPAATPPSPKGG 953
Query: 298 ----SSPWMEISGPPFEIGSAPAGVDDTPVNMDSP-PIALDGPPIKVSGAPDKRERAERP 352
S W PP +P G TP +P P A P K A + A P
Sbjct: 954 PATPSPKWAPT--PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP 1011
Query: 353 PV--------EEEAAEMEGAADAAEGGKVPSPGYGSPAA-----GAASADTAARAAP-AA 398
P A A PSP GSPAA GA + A +P
Sbjct: 1012 PAVTPPSPKGSPAATPFPKGASTPPAATPPSPK-GSPAATPLPKGAPTTPAATLPSPKGG 1070
Query: 399 PADPD-------SGATPEDPDSGTAPADPDS-------------GAFAADPDSGAAPAAP 438
PA P ATP P G A P G A P GA P P
Sbjct: 1071 PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGA-PTTP 1129
Query: 439 A----DPDSGAAPDAP--ADPDSGAAPDAP----ADPDAGAAPEAPAA-PAAAETRAAHV 487
A P G A P A A P +P A P AP PAA P + + A
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1189
Query: 488 AP-AAPDAGAPTAPAASATRAAQVRRAASAAP-ASGARRKIHLRPPSPE----IQAADPP 541
+P AP A T P+ A + A P A+ K L PSP+ AA PP
Sbjct: 1190 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1249
Query: 542 TPR 544
+P+
Sbjct: 1250 SPK 1252
Score = 63.2 bits (152), Expect = 1e-09
Identities = 130/535 (24%), Positives = 169/535 (31%), Gaps = 117/535 (21%)
Query: 36 AAAPGAGPSPAEEMETEPPHNEPIPVEND-----GEACGPPEVSRPNFQVLNPAFREAGA 90
AA P PSP T PP P P G PP PN V+ P + G
Sbjct: 1245 AATP---PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301
Query: 91 HGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPS--GVHAGLEAFGPAL--MEPGAFSG 146
+ SPP P A PS G T G P+ V P L P + G
Sbjct: 1302 --ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG 1359
Query: 147 ARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQVPDLAPGGPGAAGVPGAPPEEPQALR 206
P P A P PA S P P P G P +P P + +
Sbjct: 1360 PTTPSSKEGPTPPAATPSHKGGPAMTPPS------PKRGPAIPSPKGDPTSPAVIPLSPK 1413
Query: 207 --PAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSAV 264
PA +R G + P + D PP ++ V A+SA
Sbjct: 1414 KAPATPVTREGAATPSK-------------GDLTPPAVTPV--------SLKKAPATSAP 1452
Query: 265 RLTPAANAPPLWVPGAIGSPSQEAVRPPSN---------FTGSSPWMEISGP-------- 307
+ PA P + G P+ AV PPS T SSP + P
Sbjct: 1453 KGGPAT-------PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL 1505
Query: 308 PFEIGSAPAGVDDTPVNMDSP-----------------------PIALDGP-PIKVSGAP 343
P I S+P V TP + P P A+ P P K P
Sbjct: 1506 PAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIP 1565
Query: 344 DKRERAERPPVEEEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPD 403
+E P +E ++ +G P PA + S + AP PA
Sbjct: 1566 TPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSP----KEAPTPPA--- 1618
Query: 404 SGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAPA 463
TP P+ G A P G + P P S D+P P S
Sbjct: 1619 --VTPPSPEKGPATPAP----------KGTPTSPPVTPSS--LKDSPTSPASVTCKMGAT 1664
Query: 464 DPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAP 518
P A A P A + VAPA TAP + Q +++++ +P
Sbjct: 1665 VPQASKGLPAKKGPTA--LKEVLVAPAPESTPIITAP---TRKGPQTKKSSATSP 1714
Score = 37.0 bits (84), Expect = 0.097
Identities = 38/131 (29%), Positives = 48/131 (36%), Gaps = 11/131 (8%)
Query: 381 PAAGAASADTAARAAPAAPADPDSGATPED-PDSGTAPADPDSGAFAADPDSGAAPAAPA 439
P + A S TAA P P P+ P S A P F + + P
Sbjct: 27 PMSSALSV-TAALGQPGPTLPPPCSPAPQQCPLSAANQASP----FPSPSTIASTPLEVP 81
Query: 440 DPDSGAAPDAPADPDSGAAPDAPAD-PDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPT 498
P S + P G AP+AP P+ P +PAA A A A P + AP
Sbjct: 82 FPQSSSGTALPL----GTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPL 137
Query: 499 APAASATRAAQ 509
A A A + Q
Sbjct: 138 ALVALAPHSVQ 148
Score = 30.4 bits (67), Expect = 9.0
Identities = 38/144 (26%), Positives = 52/144 (36%), Gaps = 10/144 (6%)
Query: 420 PDSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAA 479
P S A + G P S A P + A+P A E P ++
Sbjct: 27 PMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSS 86
Query: 480 AETRAA-HVAPAAPD-----AGAPTAPAASATRAAQVRRAASAAPASGA-RRKIHLRPPS 532
+ T AP AP G P +PAA A + + P+S A + L P S
Sbjct: 87 SGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHS 146
Query: 533 PEIQAADPP---TPRPTRASAWRG 553
+ +A PP T P+ A A G
Sbjct: 147 VQKSSAFPPNLLTSPPSVAVAESG 170
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 86.7 bits (213), Expect = 1e-16
Identities = 147/560 (26%), Positives = 196/560 (35%), Gaps = 101/560 (18%)
Query: 37 AAPGAGPS-----PAEEM-ETEPP--HNEPIPVENDGEACGPPEVSRPNFQVLNPAFREA 88
+AP AGP+ PA E PP + P PV + G A G + L + E
Sbjct: 73 SAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 132
Query: 89 GAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFP-----SGVHAGLEAFGPALMEPGA 143
A G + P+ + + G P P +G GL P+
Sbjct: 133 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 192
Query: 144 FSGARPGLGGYSP-------PPEEAMPFE---FDQPAQRGCSQLLLQVPDLAPGGPGAAG 193
G R + S P P +PA R S + A GP A G
Sbjct: 193 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 252
Query: 194 VPGAP--PEEP-----QALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVI 246
P AP P +P QALRP + +PP ++ P G S P +
Sbjct: 253 TPRAPAHPSQPKPKGLQALRPPQV------TPPRKDAAP------ALGPLSSSP-----L 295
Query: 247 AQVDGSSQFAAVAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISG 306
A S+ + A S L PP ++GSP+ +A +F S P ++
Sbjct: 296 ATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH---SFLPSPPLSPLAT 352
Query: 307 PPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAEMEGAAD 366
PP + +PP AL PP++ +P PP+ A A +
Sbjct: 353 PPPQ----------------APP-ALALPPLQAPPSPPAS-----PPLSPLATPSPQAPN 390
Query: 367 A-------AEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATP-EDPDSGTAPA 418
A A PSP +P + AS + A P + A P A P + P S PA
Sbjct: 391 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS--PPA 448
Query: 419 DPDSGAFAADPDSG----AAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAP 474
P A P AAP AP A A P A P PA G AP +P
Sbjct: 449 SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSP 507
Query: 475 AA-----PAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAP---ASGARRKI 526
+A P A A AAP P +P AS T A RR + P SG R +
Sbjct: 508 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP-RRPPTPGPDTSVSGPRLTL 566
Query: 527 HLRPPSPEIQAADPPTPRPT 546
L P P PP+ P+
Sbjct: 567 ALAPGPP-----PPPSRSPS 581
Score = 78.6 bits (192), Expect = 3e-14
Identities = 116/460 (25%), Positives = 148/460 (32%), Gaps = 82/460 (17%)
Query: 129 AGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQVPDLAPGG 188
AG A PA PG + PG PP A G L + GG
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA-----GG 64
Query: 189 PGAAGVP-GAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPG-LSRVI 246
G A +P AP P A RG +PP + T P + G + PG L +
Sbjct: 65 IGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 124
Query: 247 AQVDGSSQFAAVAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISG 306
++ A A+ A P + A+ + S P
Sbjct: 125 LRISAEETVARGKATEA--------------------PKRSALSAGARRDTSGPTPGTPS 164
Query: 307 PPFEIGSAPAGVD---DTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAEMEG 363
P S AG + P P +GP VS A + P AA
Sbjct: 165 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP-----AARRRP 219
Query: 364 AADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPD----------- 412
+A GG + P S ++ A + AR+ P+A P + A P P
Sbjct: 220 SA----GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 275
Query: 413 -----SGTAPA-DPDSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAA-------- 458
APA P S + A P A P+ A P P PA P S A
Sbjct: 276 VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 335
Query: 459 -------PDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVR 511
P P P A P+AP A A +A PA+P P+ A A V
Sbjct: 336 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 395
Query: 512 RAASAAPASGARRKIHLRPPSPEIQAA-DPPTPRPTRASA 550
AP S PPSP +QA PP P SA
Sbjct: 396 --LLQAPFS--------PPPSPPVQAPFSPPASPPVSPSA 425
Score = 73.9 bits (180), Expect = 7e-13
Identities = 132/545 (24%), Positives = 187/545 (34%), Gaps = 91/545 (16%)
Query: 30 PLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQV---LNPAFR 86
PL +P + P A +P P + + +A PP+V+ P L P
Sbjct: 239 PLSSPARSGPSARGTPRAPAHPSQPKPKGL------QALRPPQVTPPRKDAAPALGPLSS 292
Query: 87 EAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSG 146
A S S PP + P PSL TL P A P L +F
Sbjct: 293 SPLATPSPSAPPSPSAP-----PSL----QTLPSPPATPPSQATTSLGSPTLQATHSFLP 343
Query: 147 ARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQVPDLAPGGPGAAGVPGAPPEEPQALR 206
+ P L + PP +A P P LQ P P P + + P+ P AL
Sbjct: 344 SPP-LSPLATPPPQAPPALALPP---------LQAPPSPPASPPLSPLATPSPQAPNAL- 392
Query: 207 PAKAGSRGGYSPPPEETM--PFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSAV 264
A + +SPPP + PF SPP +S + +A+
Sbjct: 393 -AVHLLQAPFSPPPSPPVQAPF----------SPP------------ASPPVSPSATPPS 429
Query: 265 RLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDTPVN 324
+ P+ APPL VP + P+ + P + +P ++ PP ++ P P
Sbjct: 430 QAPPSLAAPPLQVPPS--PPASPPMSPSATPPPQAP-PPLAAPPLQLAKPPP---QAPPA 483
Query: 325 MDSPPI-ALDGPPIKVSGAPDKRERAERPPVEEEAAEMEGAADAAEGGKVPSPGYGSPAA 383
+ +PP+ AL PP G A P + A +P P +
Sbjct: 484 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA------APLLQVPPS 537
Query: 384 GAASADTAARAAPAAPADPDSGATPE-----DPDSGTAPADPDSGAFAADPDSGAAPAAP 438
AS A P P S + P P P+ S + +G + +A
Sbjct: 538 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 597
Query: 439 ADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPT 498
+ P+ D+ P+ GAA P D + A A + A A AP AP P
Sbjct: 598 STPEELRGYDS--GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 655
Query: 499 APAASATRAAQVRRA---ASAAPASGARRKIHLRP-PSPEIQAADPPTPRPTRASAWRGK 554
SA + SA PA GA L P PSP +A+A G
Sbjct: 656 TGPGSADGLCTIYETEGPESATPAPGA-----LDPGPSPGTSGG--------KAAAGAGA 702
Query: 555 SESSR 559
SSR
Sbjct: 703 GASSR 707
Score = 63.2 bits (152), Expect = 1e-09
Identities = 103/422 (24%), Positives = 137/422 (32%), Gaps = 72/422 (17%)
Query: 19 PPEIGEQPEQPPLEAPGAAAPGA------------GPSPAEEMETEPPHNEPIPVENDGE 66
PP P PL P AP A PSP + PP + P+
Sbjct: 369 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 428
Query: 67 ACGPPEVSRPNFQV-----LNPAFREAGAHGSYSPPPEEAMPFEAEQPSLGG----FWPT 117
+ PP ++ P QV +P + +PPP A P + +P P
Sbjct: 429 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 488
Query: 118 LEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQL 177
L+ P G F P+ P + P PP A P P+ L
Sbjct: 489 LQALPSPPASFPGQAPFSPSASLPMSPLATPPP----QAPPVLAAPLLQVPPSPPASPTL 544
Query: 178 L------LQVPDLAPGGPG-----AAGVPGAPPEEPQAL--RPAKAGSRGGYSPPPEETM 224
PD + GP A G P P P + P AG + PEE
Sbjct: 545 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 604
Query: 225 PFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSAVRLTPAANAPPLWVPGAIGSP 284
++ EG SPPP ++ AA ++ R APPL GA G+P
Sbjct: 605 GYDSGPEGGAAASPPP-----------DAELAACHPAAWSR----GPAPPLAFRGAPGAP 649
Query: 285 SQEAVRPPSNFTGSSPWM----EISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVS 340
PP+ GS+ + E GP AP +D P S A G S
Sbjct: 650 ---LPWPPATGPGSADGLCTIYETEGPE-SATPAPGALDPGPSPGTSGGKAAAGAGAGAS 705
Query: 341 GAPDKRERAERPPVEEEAAE----------MEGAADAAEGGKVPSPGYGSPAAGAASADT 390
K+ R P+ A + AA+ A GG PG G+ G
Sbjct: 706 SRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPG-GAEGGGVTGGAR 764
Query: 391 AA 392
AA
Sbjct: 765 AA 766
Score = 56.2 bits (134), Expect = 2e-07
Identities = 86/345 (24%), Positives = 122/345 (35%), Gaps = 71/345 (20%)
Query: 259 AASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAP--- 315
A + A TPAA AP L P GSP RPP T ++ + + G +G P
Sbjct: 8 AKAGAAARTPAARAPGLLTPRPPGSP-----RPPPPVTPAA--LRVLGAAGAVGRKPLAE 60
Query: 316 -------AGVDDT-----PVNMDSPPIALDG---PPIKVSG-----APDKRERAERP-PV 354
A + ++ P PP + G PP K + +P + RP P+
Sbjct: 61 RAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 120
Query: 355 EEEAAEMEGAADAAEGGKVPSPGYGSPAAGA----------ASADTAARAAPAAPAD--- 401
++ + A G +P + +AGA + AR + AA +
Sbjct: 121 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 180
Query: 402 --PDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAPAD------- 452
P A P P G + + + S PAA P +G PA
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPS---PAARRRPSAGGGLQRPASRSLSSSA 237
Query: 453 -PDSGAA---PDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAA 508
P S A P A P A A P P R V P DA P +S+ A
Sbjct: 238 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 297
Query: 509 QVRRAASAAPASGARRKIHLRPPSPEIQAADPPTPRPTRASAWRG 553
+ SA P+ A PPS + + P TP P++A+ G
Sbjct: 298 P---SPSAPPSPSA-------PPSLQTLPSPPATP-PSQATTSLG 331
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 85.9 bits (211), Expect = 2e-16
Identities = 137/558 (24%), Positives = 191/558 (34%), Gaps = 79/558 (14%)
Query: 29 PPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAFREA 88
PPLE + AP + +P + T P N P + PP + + + P
Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLP--------SLAPPPLQTASAPLTTPHLE-- 559
Query: 89 GAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGAR 148
+PP P +A L T P PS + PAL P
Sbjct: 560 ------TPPCPAPCPLQAPPSPL-----TTPPPETPSSIATPPPQAPPALASPPLQGLPS 608
Query: 149 PGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQVPDLAPGGPGAAGVPGAPPEEPQALRPA 208
P L + PP +A P P LQ P P P + + P+ P AL A
Sbjct: 609 PPLSPLATPPPQAPPXLALPP---------LQAPPSPPASPPLSPLATPSPQAPNAL--A 657
Query: 209 KAGSRGGYSPPPEETMPFELDGEGFGDDSP--------PPGLSRVIAQVDGSSQFAAVAA 260
+ +SPPP + SP PP L+ QV S + +
Sbjct: 658 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 717
Query: 261 SSAV---RLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWME--ISGPPFEIG-SA 314
SA + P APPL VP PS A P S P + ++ PP ++ S
Sbjct: 718 PSATPPPQAPPPLAAPPLQVP-----PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP 772
Query: 315 PAGVDDTPVNMDSP--PIALDGPPIKVSGAPDKRERAERPPVEEEAAEMEGAADAAEGGK 372
PA + +P+ P P AL PP++ +P + P + M A
Sbjct: 773 PASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 832
Query: 373 --VPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPE-----DPDSGTAPADPDSGAF 425
+ +P P + AS A P P S + P P P+ S
Sbjct: 833 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 892
Query: 426 AADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAA 485
+ +G + +A + P+ D+ P+ GAA P D + A A + A A
Sbjct: 893 SGPDLAGHSSSATSTPEELRGYDS--GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 950
Query: 486 HVAPAAPDAGAPTAPAASATRAAQVRRA---ASAAPASGARRKIHLRP-PSPEIQAADPP 541
AP AP P SA + SA PA GA L P PSP
Sbjct: 951 RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA-----LDPGPSPGTSGG--- 1002
Query: 542 TPRPTRASAWRGKSESSR 559
+A+A G SSR
Sbjct: 1003 -----KAAAGAGAGASSR 1015
Score = 85.5 bits (210), Expect = 2e-16
Identities = 141/566 (24%), Positives = 200/566 (35%), Gaps = 80/566 (14%)
Query: 26 PEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAF 85
P PPL P AP + PS ++T P P + PP + P+ Q + P
Sbjct: 332 PPSPPLATPLPLAPPS-PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ 390
Query: 86 --REAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGA 143
+ +PP A+ SLG PTL+ H+ L P +
Sbjct: 391 VPHSLTSPSLQAPPSPLALSSLQATTSLGS--PTLQ------ATHSFL-TMSPRQTQASL 441
Query: 144 FSGARPGLGGYSPPPEEA-MPFEFDQPAQRGCSQLL--LQVPDLAPGGPGAAGVPGAPPE 200
S +RP PP +A + P Q S + L P + + P+
Sbjct: 442 TSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ 501
Query: 201 EP-QALRPAKAGSRGGYSPPPEETMPFELDG---EGFGDDSPPPGLSRVIAQVDGSSQFA 256
P +L ++ +PP +T P L E +PPP
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP---------------- 545
Query: 257 AVAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGS--SPWME----ISGPPFE 310
+ +SA TP PP P + +P PP S +P + ++ PP +
Sbjct: 546 -LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQ 604
Query: 311 -IGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAEMEGAADA-- 367
+ S P TP P +AL PP++ +P PP+ A A +A
Sbjct: 605 GLPSPPLSPLATPPPQAPPXLAL--PPLQAPPSPPAS-----PPLSPLATPSPQAPNALA 657
Query: 368 -----AEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATP---------EDPDS 413
A PSP +P + AS + A P + A P A P P S
Sbjct: 658 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 717
Query: 414 GTAPADPDSGAFAADPDSGAAPAAPADPD-SGAAPDAPADPDSGAAP----------DAP 462
+A P + A P P+ PA P S +A P P AAP P
Sbjct: 718 PSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP 777
Query: 463 ADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGA 522
P A P+AP A A +A PA+ AP +P+AS + A P A
Sbjct: 778 MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 837
Query: 523 -RRKIHLRPP-SPEIQA-ADPPTPRP 545
++ PP SP +QA PPTP P
Sbjct: 838 PLLQVPPSPPASPTLQAPRRPPTPGP 863
Score = 75.1 bits (183), Expect = 3e-13
Identities = 116/517 (22%), Positives = 159/517 (30%), Gaps = 96/517 (18%)
Query: 19 PPEIGEQPEQPPLEAPGAAAP----GAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVS 74
PPE PP +AP A A G P + T PP P +A P S
Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639
Query: 75 RPNFQVLNPAFREAGA------HGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGV- 127
P + P+ + A +SPPP P F P P PS
Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPP--------SPPVQAPFSPPASPPVSPSATP 691
Query: 128 --HAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQVPDLA 185
A P L P + + P +PPP+ P LQVP
Sbjct: 692 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP----------LQVPPSP 741
Query: 186 PGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRV 245
P P + PP P L + PP + P SPP L
Sbjct: 742 PASPPMSPSATPPPRVPPLL-----------AAPPLQVPP-----------SPPASLP-- 777
Query: 246 IAQVDGSSQFAAVAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEIS 305
++P A PP P P Q PP++F G +P+ +
Sbjct: 778 --------------------MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 817
Query: 306 GPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKR---ERAERPPVEEEAAEME 362
P + P +PP+ L P ++V +P + RPP +
Sbjct: 818 SLPMSPLATPP--------PQAPPV-LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 868
Query: 363 G-AADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPD 421
G A P P SP++ + D A ++ A + P+ G A + P
Sbjct: 869 GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP- 927
Query: 422 SGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAE 481
PD+ A PA G AP GA P G+A
Sbjct: 928 -------PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 980
Query: 482 TRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAP 518
+A AP A D G + A A+S +P
Sbjct: 981 PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 1017
Score = 66.6 bits (161), Expect = 1e-10
Identities = 141/633 (22%), Positives = 199/633 (31%), Gaps = 122/633 (19%)
Query: 26 PEQPPLEAPGAAA------PGAGPSPAEEMETEPP--HNEPIPVENDGEACGPPEVSRPN 77
PE P P +A P + P + E PP + P PV + G A G
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130
Query: 78 FQVLNPAFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFP-----SGVHAGLE 132
+ L + E A G + P+ + + G P P +G GL
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 190
Query: 133 AFGPALMEPGAFSGARPGLGGYSP-------PPEEAMPFE---FDQPAQRGCSQLLLQVP 182
P+ G R + S P P +PA R S +
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250
Query: 183 DLAPGGPGAAGVPGAP--PEEP-----QALRPAK-------------------------A 210
A GP A G P AP P +P QALRP + +
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 310
Query: 211 GSRGGYSPPPEET---MPFELDGEG-------FGDDSP--PPGLSRVIAQ-VDGSSQFAA 257
G++ PPP+ +P L SP PP L + + SQ
Sbjct: 311 GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370
Query: 258 VAASSAVRLTPAANA-PPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIG---- 312
+ ++ P+ PP+ VP ++ SPS +A P + + P +
Sbjct: 371 SMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFL 430
Query: 313 -----------SAPAGVDDTPVNMDSPPIALD-----GPPIKVSGAPDKRERAERPPVEE 356
++P+ TP DSPP+ PP++ S +P + +
Sbjct: 431 TMSPRQTQASLTSPSRPASTPP--DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP 488
Query: 357 EAAEMEGAADAAEG-------------GKVPSPGYGSPAAGAASADTAARAAPAAPADPD 403
A A+ + + + P +P A + + A P
Sbjct: 489 LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT 548
Query: 404 SGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGA-----APDAPADPDSGAA 458
+ A P T P P A P P P P S A AP A A P
Sbjct: 549 ASAPLTTPHLETPPC-PAPCPLQAPPSPLTTPP-PETPSSIATPPPQAPPALASPPLQGL 606
Query: 459 PDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAP 518
P P P A P+AP A +A PA+P P+ A A V AP
Sbjct: 607 PSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH--LLQAP 664
Query: 519 ASGARRKIHLRPPSPEIQAA-DPPTPRPTRASA 550
S PPSP +QA PP P SA
Sbjct: 665 FS--------PPPSPPVQAPFSPPASPPVSPSA 689
Score = 62.8 bits (151), Expect = 2e-09
Identities = 105/447 (23%), Positives = 143/447 (31%), Gaps = 82/447 (18%)
Query: 129 AGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQVPDLAPGG 188
AG A PA PG + PG PP A G L + GG
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA-----GG 64
Query: 189 PGAAGVPGAPPE-----------EPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDS 237
G A +P + P A RP +G RG +PP + T P + G +
Sbjct: 65 IGGATIPESAPRAGPTRSAGTSSRNPASRPPASG-RGERAPPAKNTSPGPVSSPGRASGT 123
Query: 238 PPPG-LSRVIAQVDGSSQFAAVAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFT 296
PG L + ++ A A+ A P + A+ +
Sbjct: 124 TRPGPLGQKGLRISAEETVARGKATEA--------------------PKRSALSAGARRD 163
Query: 297 GSSPWMEISGPPFEIGSAPAGVD---DTPVNMDSPPIALDGPPIKVSGAPDKRERAERPP 353
S P P S AG + P P +GP VS A + P
Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP- 222
Query: 354 VEEEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPD- 412
AA +A GG + P S ++ A + AR+ P+A P + A P P
Sbjct: 223 ----AARRRPSA----GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274
Query: 413 ---------------SGTAPA-DPDSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSG 456
APA P S + A P A P P AA PA
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPAT---- 330
Query: 457 AAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASA 516
P P AP +P+AP + +T P+ P AP + T Q +
Sbjct: 331 LPPSPPLATPLPLAPPSPSAPPSLQT-----LPSPPATPPSQAPPSMTTPPMQAPPSLQT 385
Query: 517 APASGARRKIHLRPPSPEIQAADPPTP 543
P + SP +QA PP+P
Sbjct: 386 IPPIQVPHSL----TSPSLQA--PPSP 406
Score = 60.8 bits (146), Expect = 6e-09
Identities = 89/331 (26%), Positives = 115/331 (34%), Gaps = 53/331 (16%)
Query: 259 AASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAP--- 315
A + A TPAA AP L P GSP RPP T ++ + + G +G P
Sbjct: 8 AKAGAAARTPAARAPGLLTPRPPGSP-----RPPPPVTPAA--LRVLGAAGAVGRKPLAE 60
Query: 316 --AGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAEMEGAADAAEGGKV 373
G+ + P A P + +G R A RPP E A G V
Sbjct: 61 RAGGIGGATI----PESAPRAGPTRSAGT-SSRNPASRPPASGR-GERAPPAKNTSPGPV 114
Query: 374 PSPGYGS-------------------PAAGAASADTAARAAPAAPADPD-SGATPEDPDS 413
SPG S A + + R+A +A A D SG TP P
Sbjct: 115 SSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 174
Query: 414 GTAPADPDSGAFAA--DPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAP 471
A +G P A P P + + A + +P A P AG
Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 234
Query: 472 EAPAAPAAAETRAAHVAPA--APDA-GAPTAPA---------ASATRAAQVR-RAASAAP 518
+ PA+ + + + +PA P A G P APA A R QV AAP
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP 294
Query: 519 ASGARRKIHLRPPSPEIQAADPPTPRPTRAS 549
A G L PSP A P P A+
Sbjct: 295 ALGPLSSSPLATPSPSGTKARPVPPPDNAAT 325
Score = 55.8 bits (133), Expect = 2e-07
Identities = 98/402 (24%), Positives = 133/402 (33%), Gaps = 60/402 (14%)
Query: 18 IPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPN 77
+PP P P P AP +P ++ PP + P+ PP ++ P
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765
Query: 78 FQVLNPAFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPA 137
QV P+ + + PP +A P A P L+ P G F P+
Sbjct: 766 LQV-PPSPPASLPMSPLAKPPPQAPPALAT--------PPLQALPSPPASFPGQAPFSPS 816
Query: 138 LMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLL------LQVPDLAPGGPG- 190
P + P PP A P P+ L PD + GP
Sbjct: 817 ASLPMSPLATPPP----QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 872
Query: 191 ----AAGVPGAPPEEPQAL--RPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSR 244
A G P P P + P AG + PEE ++ EG SPPP
Sbjct: 873 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP---- 928
Query: 245 VIAQVDGSSQFAAVAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWM-- 302
++ AA ++ R APPL GA G+P PP+ GS+ +
Sbjct: 929 -------DAELAACHPAAWSR----GPAPPLAFRGAPGAP---LPWPPATGPGSADGLCT 974
Query: 303 --EISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAE 360
E GP AP +D P S A G S K+ R P+ A
Sbjct: 975 IYETEGPE-SATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQAS 1033
Query: 361 ----------MEGAADAAEGGKVPSPGYGSPAAGAASADTAA 392
+ AA+ A GG PG G+ G AA
Sbjct: 1034 VVQHLLSRTLLLAAAEGAAGGSGGGPG-GAEGGGVTGGARAA 1074
Score = 36.6 bits (83), Expect = 0.13
Identities = 44/145 (30%), Positives = 56/145 (38%), Gaps = 16/145 (11%)
Query: 431 SGAAPAAPADPDSGAAPDAPADPDSGAAPDAPAD----PDAGAAPEAPAAPAAAETRAAH 486
+GAA PA G P P PA AGA P A A A
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69
Query: 487 VAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSPEIQAADPPTPRPT 546
+ +AP AG PT A +++ R AS PASG + PP+ + P P
Sbjct: 70 IPESAPRAG-PTRSAGTSS-----RNPASRPPASGRGER---APPAK--NTSPGPVSSPG 118
Query: 547 RAS-AWRGKSESSRGRRVYYDEGVA 570
RAS R +G R+ +E VA
Sbjct: 119 RASGTTRPGPLGQKGLRISAEETVA 143
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 84.3 bits (207), Expect = 5e-16
Identities = 137/600 (22%), Positives = 214/600 (35%), Gaps = 91/600 (15%)
Query: 19 PPEIGEQPEQPPLEAPG--AAAPGAGPSPAEEME-TEPPHNEPIPVENDGEACGPPEVSR 75
PP P +PP + PG + PG PA+ T+P +P V+ + PP ++
Sbjct: 304 PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQ---PPGTTK 360
Query: 76 PNFQVLNPAFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFG 135
P Q L PA A GS P E+ P QP G P +QPG +
Sbjct: 361 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPA-QQPGPAKPPTQQVGTPK 419
Query: 136 PALMEPGAFSGAR-----------PGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQVPDL 184
P +PG S A+ PG G P ++A P + Q G ++ Q+P
Sbjct: 420 PLAQQPGLQSPAKAPGPTKTPVQQPGPG--KIPAQQAGPGK-TSAQQTGPTKPPSQLPGP 476
Query: 185 APGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPP---PG 241
A P G PP++P + +P + G PPP++ P + + G PP PG
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKP-PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535
Query: 242 LSRVIAQVDGSSQFAAVAASSAVRLTPAAN--APPLWVPGAIGSPSQ---EAVRPPSNFT 296
++ AQ ++ +A ++ V T + PP P A PSQ + + P N T
Sbjct: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTT 595
Query: 297 --------------------------GSSP---------WMEISGPPFEIGSAPAGVDDT 321
G +P W+ ++ G D
Sbjct: 596 ELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQM----KRALGGDLA 651
Query: 322 PVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAEMEGAADAAEGGKVPSPGYGSP 381
PV SP L P+ + A K P ++ + + AA + K P P P
Sbjct: 652 PV-PSSPQPKLKTAPVTTTSAVSKSS-----PQPQQTSPKKDAAPKQDLSKAPEPKKPPP 705
Query: 382 AAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAP--- 438
+ + A P + DS + P P + P++ D A D P
Sbjct: 706 LVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTD 765
Query: 439 --ADPDSGAAPDAPADPDSGAAPDAPADP-DAGAAPEAPAAPAAAETRAAHVAPAAPDAG 495
+ + PD P+ A + P +A + + P E + + A P
Sbjct: 766 LVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPA 825
Query: 496 APT------APAASATRAAQVRRAASAAPASGARRKIHLRP---PSPEIQAADPPTPRPT 546
+ + P++ + QV A+ K+ +P P P+ + PP PRPT
Sbjct: 826 SDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK-GSPTPPGPRPT 884
Score = 73.2 bits (178), Expect = 1e-12
Identities = 108/470 (22%), Positives = 155/470 (32%), Gaps = 99/470 (21%)
Query: 86 REAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFS 145
+E G PP + P + G L+Q G P + + +P
Sbjct: 198 KEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISS---------QQPEKIK 248
Query: 146 GARPGLGGYSPPPEEAMPFEFDQ-PAQRGCSQLLLQVPDLAPG--------GPGAAGVPG 196
PG G P + + + P QR S+ + D+ G P +
Sbjct: 249 SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ 308
Query: 197 APPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFA 256
P +P A +P S+ G + PP + P GL++ +AQ G+ +
Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPPAQ----------------PSGLTKPLAQQPGTVK-- 350
Query: 257 AVAASSAVRLTPAANAPPLWVPGAIGSPSQEA--VRPPSNFTGSS-PWMEISGPPFEIGS 313
PP+ PG P+Q +PP+ TGS P E GP + +
Sbjct: 351 ----------------PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP--KALA 392
Query: 314 APAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAEMEGAADAAEGGKV 373
P GV TP P PP + G P +P ++ + A V
Sbjct: 393 QPPGVGKTPAQQPGPA----KPPTQQVGTP-------KPLAQQPGLQSPAKAPGPTKTPV 441
Query: 374 PSPGYGS-PAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSG 432
PG G PA A T+A+ P P S G A P A P
Sbjct: 442 QQPGPGKIPAQQAGPGKTSAQQT--GPTKPPSQLP------GPAKPPPQQPGPAKPPPQQ 493
Query: 433 AAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAP 492
A P G+ P P G A +P P + P P +A+ A +PA P
Sbjct: 494 PGSAKPPSQQPGSTKPPPQQP--GPAKPSPQQPGSTKPPSQQ--PGSAKPSAQQPSPAKP 549
Query: 493 DAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSPEIQAADPPT 542
A T P V + S P L+PP+ A PP+
Sbjct: 550 SAQQSTKP---------VSQTGSGKP---------LQPPTVSPSAKQPPS 581
Score = 46.6 bits (109), Expect = 1e-04
Identities = 91/397 (22%), Positives = 136/397 (34%), Gaps = 58/397 (14%)
Query: 155 SPPPEEAMPFEFDQPAQRGCSQLLLQVPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRG 214
SP P++ P + P Q + P P G P A +A +P +A S
Sbjct: 676 SPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA-----KAKQPPEADSLS 730
Query: 215 GYSPPPEETMPFELDGEGFGDDSP-PPGLSRVIAQVDGSSQFAA---VAASSAVRLTPAA 270
+PP E ++P E D DD P P + + + SS + +S
Sbjct: 731 KPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEK 790
Query: 271 NAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDTPVNMDSPPI 330
PPL A PSQ PP+ S PF+ + P D+ + P
Sbjct: 791 TTPPLKTDSA--KPSQSF--PPTGEKVS---------PFDSKAIPRPASDSKIISHPGPS 837
Query: 331 A-----LDGPPIKVSGAPDKRERAERP-----PVEEEAAEMEGAADAAEGGKVPSPGYGS 380
+ P++ P K + P P+ + + G A G VP+P S
Sbjct: 838 SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA-GQTVPTP-QQS 895
Query: 381 PAAGAASADTAARAAPAAPADPDSGATPEDPDSG----------TAPADPDSGAFAADPD 430
P S + A TP++ +G + ++ S A P
Sbjct: 896 PKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPH 955
Query: 431 SGAAPAAPAD--PDSGAAPDAPADPDS-GAAPDAPA-------DPDAGAA----PEAPAA 476
S + P AP P P + P S G AP APA + A AA P+A A
Sbjct: 956 SQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015
Query: 477 PAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRA 513
P T P D+ + TA A ++ ++
Sbjct: 1016 PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKS 1052
Score = 42.7 bits (99), Expect = 0.002
Identities = 106/495 (21%), Positives = 154/495 (31%), Gaps = 82/495 (16%)
Query: 117 TLEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQ 176
+LE G P G+ A A G A SGA P EA + + +R +
Sbjct: 6 SLEGEGLPEGLAAAAAAGGGA-------SGAGSPSHTAIPAGMEADLSQLSEEERRQIAA 58
Query: 177 LLLQVPDLAPGG--PGAAGVP-----------------GAPPEEPQALRPAKAGSRGGYS 217
++ + L G P AA P G PP+ + +P + SR +
Sbjct: 59 VMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDT 118
Query: 218 PPPEETMP-------------FELDGEGFGDDSPPPG-------LSRVIAQVDGSSQFAA 257
E+ +P D + S PG LS V + V+ + F
Sbjct: 119 FRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDL 178
Query: 258 VAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAG 317
++ S A + V G P + ++PP P + GP G P
Sbjct: 179 ISDSEASQEETTKKQKV--VQKEQGKP-EGIIKPPLQQQPPKPIPKQQGP----GRDPLQ 231
Query: 318 VDDTPVNMDS---------PPIALDGPPIKVSGAPDKRERAERPPVEEEAAEMEGAADAA 368
D TP ++ S PP G PI+ + + A+ P + + AD
Sbjct: 232 QDGTPKSISSQQPEKIKSQPPGT--GKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIV 289
Query: 369 EGGKV----PSPGY--------GSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTA 416
G V PSP G P A + + PA P P GT
Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTV 349
Query: 417 PADPDSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAA 476
P PA P +G+ + P A P A PA
Sbjct: 350 KPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAK 409
Query: 477 PAAAETRAAHVAPAAPDAGAPT-APAASATRAAQVRRAASAAPASG-----ARRKIHLRP 530
P + P +P AP + T Q A +G A++ +P
Sbjct: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469
Query: 531 PSPEIQAADPPTPRP 545
PS A PP +P
Sbjct: 470 PSQLPGPAKPPPQQP 484
Score = 32.3 bits (72), Expect = 2.4
Identities = 36/167 (21%), Positives = 60/167 (35%), Gaps = 19/167 (11%)
Query: 384 GAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDS 443
G+ T A + +P + + P+D T S AD AP+ P P
Sbjct: 3563 GSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKV 3622
Query: 444 GAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAG-------- 495
+P +P P G A ++ P P+ + A V PA+P
Sbjct: 3623 LYSPISPLSP--GKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMS 3680
Query: 496 --APTAPAASATRAAQVR-------RAASAAPASGARRKIHLRPPSP 533
P +P A + A + + + +SGA++K+ P+P
Sbjct: 3681 DPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNP 3727
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,172,134
Number of Sequences: 37866
Number of extensions: 3310775
Number of successful extensions: 39845
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 505
Number of HSP's successfully gapped in prelim test: 1895
Number of HSP's that attempted gapping in prelim test: 17780
Number of HSP's gapped (non-prelim): 12624
length of query: 1037
length of database: 18,247,518
effective HSP length: 112
effective length of query: 925
effective length of database: 14,006,526
effective search space: 12956036550
effective search space used: 12956036550
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.