Search of human proteins with 117676365

Search of human proteins with 117676365

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117676365 tumor necrosis factor, alpha-induced protein 8
isoform a [Homo sapiens]
         (198 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117676365 tumor necrosis factor, alpha-induced protein 8 isof...   393   e-110
gi|117676370 tumor necrosis factor, alpha-induced protein 8 isof...   373   e-104
gi|59709436 tumor necrosis factor, alpha-induced protein 8-like ...   261   4e-70
gi|22748781 tumor necrosis factor, alpha-induced protein 8-like ...   231   2e-61
gi|157389001 tumor necrosis factor, alpha-induced protein 8-like...   208   2e-54
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom...    34   0.071
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom...    34   0.071
gi|27734883 tripartite motif family-like 2 [Homo sapiens]              33   0.21 
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr...    32   0.27 
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr...    32   0.27 
gi|109659849 filamin A interacting protein 1-like isoform 2 [Hom...    32   0.27 
gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo sa...    32   0.46 
gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo s...    32   0.46 
gi|55749678 ninein-like [Homo sapiens]                                 30   1.8  
gi|187608516 centaurin, beta 2 [Homo sapiens]                          30   1.8  
gi|6912236 angiopoietin-like 2 precursor [Homo sapiens]                30   1.8  
gi|38016947 complement component 5 preproprotein [Homo sapiens]        29   2.3  
gi|71061468 centromere protein E [Homo sapiens]                        29   2.3  
gi|4758648 kinesin family member 5B [Homo sapiens]                     29   3.0  
gi|55749644 UHRF1 (ICBP90) binding protein 1-like isoform a [Hom...    29   3.0  
gi|227497884 brain-enriched guanylate kinase-associated protein ...    28   3.9  
gi|13124765 brain-enriched guanylate kinase-associated protein [...    28   3.9  
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]                    28   3.9  
gi|140161498 hypothetical protein LOC23281 isoform a [Homo sapiens]    28   3.9  
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]         28   6.7  
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]         28   6.7  
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]         28   6.7  
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]         28   6.7  
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]         28   6.7  
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]         28   6.7  

>gi|117676365 tumor necrosis factor, alpha-induced protein 8 isoform
           a [Homo sapiens]
          Length = 198

 Score =  393 bits (1010), Expect = e-110
 Identities = 198/198 (100%), Positives = 198/198 (100%)

Query: 1   MHSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTRE 60
           MHSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTRE
Sbjct: 1   MHSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTRE 60

Query: 61  YTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVD 120
           YTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVD
Sbjct: 61  YTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVD 120

Query: 121 YTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKP 180
           YTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKP
Sbjct: 121 YTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKP 180

Query: 181 HLQKLCDGINKMLDEENI 198
           HLQKLCDGINKMLDEENI
Sbjct: 181 HLQKLCDGINKMLDEENI 198


>gi|117676370 tumor necrosis factor, alpha-induced protein 8 isoform
           b [Homo sapiens]
          Length = 188

 Score =  373 bits (957), Expect = e-104
 Identities = 187/188 (99%), Positives = 188/188 (100%)

Query: 11  VATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEK 70
           +ATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEK
Sbjct: 1   MATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEK 60

Query: 71  IIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSR 130
           IIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSR
Sbjct: 61  IIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSR 120

Query: 131 LLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGIN 190
           LLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGIN
Sbjct: 121 LLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGIN 180

Query: 191 KMLDEENI 198
           KMLDEENI
Sbjct: 181 KMLDEENI 188


>gi|59709436 tumor necrosis factor, alpha-induced protein 8-like 3
           [Homo sapiens]
          Length = 292

 Score =  261 bits (666), Expect = 4e-70
 Identities = 118/194 (60%), Positives = 167/194 (86%)

Query: 3   SEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYT 62
           SE E       DVF+SK+LA+QAQKKIL K+ SK++A  LIDDTSSE+ DELY+VT+E+T
Sbjct: 97  SEGEPVTAAGPDVFSSKSLALQAQKKILSKIASKTVANMLIDDTSSEIFDELYKVTKEHT 156

Query: 63  QNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYT 122
            NKKEA KI+K+LIK  IK+ ILYRNNQF+Q+EL ++EKF+KK++Q AMT+VSF++V+YT
Sbjct: 157 HNKKEAHKIMKDLIKVAIKIGILYRNNQFSQEELVIVEKFRKKLNQTAMTIVSFYEVEYT 216

Query: 123 FDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHL 182
           FDRNVLS LL+EC++++H+++QRHLT ++HGR+N+VF+HF+D EFL+ LY+  G+ +P+L
Sbjct: 217 FDRNVLSNLLHECKDLVHELVQRHLTPRTHGRINHVFNHFADVEFLSTLYSLDGDCRPNL 276

Query: 183 QKLCDGINKMLDEE 196
           +++C+GINK+LDE+
Sbjct: 277 KRICEGINKLLDEK 290


>gi|22748781 tumor necrosis factor, alpha-induced protein 8-like 1
           [Homo sapiens]
          Length = 186

 Score =  231 bits (590), Expect = 2e-61
 Identities = 105/185 (56%), Positives = 148/185 (80%)

Query: 14  DVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIK 73
           D F++K+LA+QAQKK+L KM SK++   L+DDTSSEVLDELYR TRE+T+++KEA+K++K
Sbjct: 2   DTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKMLK 61

Query: 74  NLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLN 133
           NL+K  +KL +L R +Q   +ELAL+ +F+ +   LAMT VSFHQVD+TFDR VL+  L 
Sbjct: 62  NLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAVGLL 121

Query: 134 ECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGINKML 193
           ECR++LHQ +  HLTAKSHGR+N+VF H +DC+FLAALY P   ++ HL+++C+G+ +ML
Sbjct: 122 ECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRML 181

Query: 194 DEENI 198
           DE ++
Sbjct: 182 DEGSL 186


>gi|157389001 tumor necrosis factor, alpha-induced protein 8-like 2
           [Homo sapiens]
          Length = 184

 Score =  208 bits (530), Expect = 2e-54
 Identities = 99/180 (55%), Positives = 140/180 (77%), Gaps = 2/180 (1%)

Query: 16  FNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNL 75
           F+SK+LA+QA+KK+L KM  +S+A   ID+TSSEVLDELYRV++EYT ++ +A+++IK+L
Sbjct: 4   FSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPQAQRVIKDL 63

Query: 76  IKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNEC 135
           IK  IK+A+L+RN  F   ELAL  +F++K+ Q AMT +SF +VD+TF+  VL+ LL EC
Sbjct: 64  IKVAIKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLLTEC 123

Query: 136 REMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGINKMLDE 195
           R++L ++++ HLT KSHGR+ +VFDHFSD   L ALY P  +F  HL K+CDG+ K+LDE
Sbjct: 124 RDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYGP--DFTQHLGKICDGLRKLLDE 181


>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
           sapiens]
          Length = 1133

 Score = 34.3 bits (77), Expect = 0.071
 Identities = 33/151 (21%), Positives = 68/151 (45%), Gaps = 15/151 (9%)

Query: 1   MHSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTRE 60
           +  E E  K++      S+    Q ++K   ++ +     T +   +  V+DE  R+T +
Sbjct: 196 LEQECERLKKLIDQEIKSQEEKEQEKEK---RVTTLKEELTKLKSFALMVVDEQQRLTAQ 252

Query: 61  YTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVD 120
            T  +++ +++  N  +T  KLA+     Q  + +   +EK      +L      FHQ  
Sbjct: 253 LTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEK------ELQTQTTKFHQDQ 306

Query: 121 YTFDRNVLSRLLNECREMLHQIIQRHLTAKS 151
            T    ++++L NE  +  ++ +Q+ L A S
Sbjct: 307 DT----IMAKLTNE--DSQNRQLQQKLAALS 331


>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
           sapiens]
          Length = 1135

 Score = 34.3 bits (77), Expect = 0.071
 Identities = 33/151 (21%), Positives = 68/151 (45%), Gaps = 15/151 (9%)

Query: 1   MHSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTRE 60
           +  E E  K++      S+    Q ++K   ++ +     T +   +  V+DE  R+T +
Sbjct: 196 LEQECERLKKLIDQEIKSQEEKEQEKEK---RVTTLKEELTKLKSFALMVVDEQQRLTAQ 252

Query: 61  YTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVD 120
            T  +++ +++  N  +T  KLA+     Q  + +   +EK      +L      FHQ  
Sbjct: 253 LTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEK------ELQTQTTKFHQDQ 306

Query: 121 YTFDRNVLSRLLNECREMLHQIIQRHLTAKS 151
            T    ++++L NE  +  ++ +Q+ L A S
Sbjct: 307 DT----IMAKLTNE--DSQNRQLQQKLAALS 331


>gi|27734883 tripartite motif family-like 2 [Homo sapiens]
          Length = 387

 Score = 32.7 bits (73), Expect = 0.21
 Identities = 31/148 (20%), Positives = 70/148 (47%), Gaps = 11/148 (7%)

Query: 1   MHSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTRE 60
           ++ E E++ +   +  +  NL    ++ +L + +  +   T +++   E+L  L RV RE
Sbjct: 66  LNEECEQNLQRQQECISDLNL----RETLLNQAIKLA---TELEEMFQEMLQRLGRVGRE 118

Query: 61  YTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVD 120
             +  KE+E      +++++KL I+    +  +  LAL++  K  + +    ++   +  
Sbjct: 119 NMEKLKESEARASEQVRSLLKL-IVELEKKCGEGTLALLKNAKYSLERSKSLLLEHLEPA 177

Query: 121 YTFDRNVLSRLLNECREMLHQIIQRHLT 148
           +  D   LS         + +++QRHLT
Sbjct: 178 HITD---LSLCHIRGLSSMFRVLQRHLT 202


>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
           repeats isoform 2 [Homo sapiens]
          Length = 1403

 Score = 32.3 bits (72), Expect = 0.27
 Identities = 31/146 (21%), Positives = 70/146 (47%), Gaps = 22/146 (15%)

Query: 20  NLAVQAQKKILGKMVSKSIATT---LIDDTSSEVLDELYRVTREYTQNKKEAEKII---K 73
           NL ++ +   +   VS+ +  +   +IDD + ++LD    VT++YT+ K E EK++    
Sbjct: 722 NLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLD----VTQKYTEKKLEMEKLLLEND 777

Query: 74  NLIKTVIKLAILYRNNQFNQDELALME----KFKKKVHQLAMTVVSFHQVDYTFDRNVLS 129
           +L K V +L  ++   + ++ E+  ++    + KK++ +L              D+  + 
Sbjct: 778 SLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGE--------DQEKIH 829

Query: 130 RLLNECREMLHQIIQRHLTAKSHGRV 155
            L +E   +   +  +++  K+H  V
Sbjct: 830 ALTSENTNLKKMMSNQYVPVKTHEEV 855


>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
           repeats isoform 1 [Homo sapiens]
          Length = 1416

 Score = 32.3 bits (72), Expect = 0.27
 Identities = 31/146 (21%), Positives = 70/146 (47%), Gaps = 22/146 (15%)

Query: 20  NLAVQAQKKILGKMVSKSIATT---LIDDTSSEVLDELYRVTREYTQNKKEAEKII---K 73
           NL ++ +   +   VS+ +  +   +IDD + ++LD    VT++YT+ K E EK++    
Sbjct: 735 NLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLD----VTQKYTEKKLEMEKLLLEND 790

Query: 74  NLIKTVIKLAILYRNNQFNQDELALME----KFKKKVHQLAMTVVSFHQVDYTFDRNVLS 129
           +L K V +L  ++   + ++ E+  ++    + KK++ +L              D+  + 
Sbjct: 791 SLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGE--------DQEKIH 842

Query: 130 RLLNECREMLHQIIQRHLTAKSHGRV 155
            L +E   +   +  +++  K+H  V
Sbjct: 843 ALTSENTNLKKMMSNQYVPVKTHEEV 868


>gi|109659849 filamin A interacting protein 1-like isoform 2 [Homo
           sapiens]
          Length = 893

 Score = 32.3 bits (72), Expect = 0.27
 Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 12/102 (11%)

Query: 50  VLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQL 109
           V+DE  R+T + T  +++ +++  N  +T  KLA+     Q  + +   +EK      +L
Sbjct: 2   VVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEK------EL 55

Query: 110 AMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKS 151
                 FHQ   T    ++++L NE  +  ++ +Q+ L A S
Sbjct: 56  QTQTTKFHQDQDT----IMAKLTNE--DSQNRQLQQKLAALS 91


>gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo
           sapiens]
          Length = 529

 Score = 31.6 bits (70), Expect = 0.46
 Identities = 27/121 (22%), Positives = 58/121 (47%), Gaps = 11/121 (9%)

Query: 2   HSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYR----- 56
           H++ E++++   +    + LAV+A KK     +S   A+ L ++   E   +  R     
Sbjct: 337 HNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFK 396

Query: 57  ---VTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTV 113
              +   YTQ KKE E+ ++ L K + + A      +   DE++  +  ++ +H+L + +
Sbjct: 397 LKLLLESYTQQKKEQEEFLR-LEKEIREKAEKAEKRKNAADEISRFQ--ERDLHKLELKI 453

Query: 114 V 114
           +
Sbjct: 454 L 454


>gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo
           sapiens]
          Length = 446

 Score = 31.6 bits (70), Expect = 0.46
 Identities = 27/121 (22%), Positives = 58/121 (47%), Gaps = 11/121 (9%)

Query: 2   HSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYR----- 56
           H++ E++++   +    + LAV+A KK     +S   A+ L ++   E   +  R     
Sbjct: 254 HNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFK 313

Query: 57  ---VTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTV 113
              +   YTQ KKE E+ ++ L K + + A      +   DE++  +  ++ +H+L + +
Sbjct: 314 LKLLLESYTQQKKEQEEFLR-LEKEIREKAEKAEKRKNAADEISRFQ--ERDLHKLELKI 370

Query: 114 V 114
           +
Sbjct: 371 L 371


>gi|55749678 ninein-like [Homo sapiens]
          Length = 1382

 Score = 29.6 bits (65), Expect = 1.8
 Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 4/99 (4%)

Query: 41   TLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALME 100
            TL+ +    V  EL      +   +KE E + K+  K   ++ +L R NQ  +D+L+   
Sbjct: 1094 TLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLS--- 1150

Query: 101  KFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREML 139
            +   +V QL     S HQ      R  +  L     E++
Sbjct: 1151 QLNVRVLQLGQE-ASTHQAQNEEHRVTIQMLTQSLEEVV 1188


>gi|187608516 centaurin, beta 2 [Homo sapiens]
          Length = 778

 Score = 29.6 bits (65), Expect = 1.8
 Identities = 31/131 (23%), Positives = 54/131 (41%), Gaps = 19/131 (14%)

Query: 40  TTLIDDTSSEVLDELYRVTRE----YTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDE 95
           T L D T   +  +L    +E    +   KK+ EK+ +     ++K A + RN Q   +E
Sbjct: 95  TILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEE 154

Query: 96  LA-LMEKFKKKVHQLAMTVVSFHQVDYTFDRNVL-SRLLNECREMLHQIIQRHLTAKSHG 153
              ++   +K    +A+        DY    NVL S+  +E  + +   +  HL     G
Sbjct: 155 ATNILTATRKCFRHIAL--------DYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQG 206

Query: 154 RVNNVFDHFSD 164
                +D FS+
Sbjct: 207 -----YDLFSE 212


>gi|6912236 angiopoietin-like 2 precursor [Homo sapiens]
          Length = 493

 Score = 29.6 bits (65), Expect = 1.8
 Identities = 34/142 (23%), Positives = 64/142 (45%), Gaps = 12/142 (8%)

Query: 56  RVTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMT--- 112
           RVT     N KE E +++N +    K  +   NN     EL   ++  + + QL      
Sbjct: 64  RVTGAICVNSKEPEVLLENRVH---KQELELLNN-----ELLKQKRQIETLQQLVEVDGG 115

Query: 113 VVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRV-NNVFDHFSDCEFLAAL 171
           +VS  ++     RN+ SR+     ++LH+II++   A    ++ N + +  +D   LA+ 
Sbjct: 116 IVSEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQLENRILNQTADMLQLASK 175

Query: 172 YNPFGNFKPHLQKLCDGINKML 193
           Y    +   HL  L    ++++
Sbjct: 176 YKDLEHKYQHLATLAHNQSEII 197


>gi|38016947 complement component 5 preproprotein [Homo sapiens]
          Length = 1676

 Score = 29.3 bits (64), Expect = 2.3
 Identities = 11/35 (31%), Positives = 22/35 (62%)

Query: 89   NQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTF 123
            N F+ D L   +K KKK+ +  ++++S+   DY++
Sbjct: 1032 NIFHSDPLIEKQKLKKKLKEGMLSIMSYRNADYSY 1066


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 29.3 bits (64), Expect = 2.3
 Identities = 21/112 (18%), Positives = 54/112 (48%), Gaps = 1/112 (0%)

Query: 3    SEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATT-LIDDTSSEVLDELYRVTREY 61
            S  ++  E + D   +++L +Q + +I    + +   T   +    SE  D+L  + ++ 
Sbjct: 1752 SNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDL 1811

Query: 62   TQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTV 113
              +  + ++ I+ L     +L  L ++    Q +++ ME+ KK++   ++T+
Sbjct: 1812 ENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTL 1863



 Score = 28.9 bits (63), Expect = 3.0
 Identities = 28/135 (20%), Positives = 65/135 (48%), Gaps = 5/135 (3%)

Query: 4    EAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTL--IDDTSSEVLDELYRVTREY 61
            E ++ KE   +   +++L +Q + K   +M+SK    T+  + +  SE   ++  + ++ 
Sbjct: 1904 ERDQLKESLQET-KARDLEIQQELKT-ARMLSKEHKETVDKLREKISEKTIQISDIQKDL 1961

Query: 62   TQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDY 121
             ++K E +K I+ L K  ++L  +  +   +  ++  ME+ KK+     +++ S    ++
Sbjct: 1962 DKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNF 2021

Query: 122  TFDRNVLSRLLNECR 136
               +  L   L E R
Sbjct: 2022 QLTKK-LHESLEEIR 2035


>gi|4758648 kinesin family member 5B [Homo sapiens]
          Length = 963

 Score = 28.9 bits (63), Expect = 3.0
 Identities = 25/103 (24%), Positives = 48/103 (46%), Gaps = 9/103 (8%)

Query: 1   MHSEAEESKEVATDVFNS-KNLAVQAQKKILGKMVSKSIATTLIDD-------TSSEVLD 52
           + +E + SKE   +V  + + LAV   +K   ++  K+    L+ D       T + +  
Sbjct: 477 LQAENDASKEEVKEVLQALEELAVNYDQKSQ-EVEDKTKEYELLSDELNQKSATLASIDA 535

Query: 53  ELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDE 95
           EL ++       KK A +++ +L+K + ++ I   NN   Q E
Sbjct: 536 ELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPE 578


>gi|55749644 UHRF1 (ICBP90) binding protein 1-like isoform a [Homo
           sapiens]
          Length = 1464

 Score = 28.9 bits (63), Expect = 3.0
 Identities = 34/129 (26%), Positives = 50/129 (38%), Gaps = 25/129 (19%)

Query: 78  TVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVL-----SRLL 132
           TV + +IL+ N QF  D    + +F   V++L     S   VD   D  +L     S + 
Sbjct: 532 TVDERSILWLN-QFLLDLKQSLNQFMA-VYKLNDNSKSDEHVDVRVDGLMLKFVIPSEVK 589

Query: 133 NECREMLHQIIQ-----------RHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPH 181
           +EC +   + I            RH     H  +  +F  F DC+F +  Y  F      
Sbjct: 590 SECHQDQPRAISIQSSEMIATNTRHCPNCRHSDLEALFQDFKDCDFFSKTYTSF------ 643

Query: 182 LQKLCDGIN 190
             K CD  N
Sbjct: 644 -PKSCDNFN 651


>gi|227497884 brain-enriched guanylate kinase-associated protein
           [Homo sapiens]
          Length = 593

 Score = 28.5 bits (62), Expect = 3.9
 Identities = 35/156 (22%), Positives = 74/156 (47%), Gaps = 9/156 (5%)

Query: 22  AVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIK 81
           A+Q QK  L K +S +  T  ++   +E     + +  E  + ++E EK+ + L +    
Sbjct: 6   ALQEQKGELRKRLSYT--THKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSN 63

Query: 82  LAILYRNNQFNQDELALM-EKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLH 140
              L R NQ  +D+L  M + ++++   L+  +V+ +   +  +  V    L+E  E+  
Sbjct: 64  YMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALN--SHLLEAKVTIDKLSEDNELYR 121

Query: 141 Q----IIQRHLTAKSHGRVNNVFDHFSDCEFLAALY 172
           +      Q    ++++GRV+ V +  SD +   +L+
Sbjct: 122 KDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLH 157


>gi|13124765 brain-enriched guanylate kinase-associated protein
           [Homo sapiens]
          Length = 593

 Score = 28.5 bits (62), Expect = 3.9
 Identities = 35/156 (22%), Positives = 74/156 (47%), Gaps = 9/156 (5%)

Query: 22  AVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIK 81
           A+Q QK  L K +S +  T  ++   +E     + +  E  + ++E EK+ + L +    
Sbjct: 6   ALQEQKGELRKRLSYT--THKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSN 63

Query: 82  LAILYRNNQFNQDELALM-EKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLH 140
              L R NQ  +D+L  M + ++++   L+  +V+ +   +  +  V    L+E  E+  
Sbjct: 64  YMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALN--SHLLEAKVTIDKLSEDNELYR 121

Query: 141 Q----IIQRHLTAKSHGRVNNVFDHFSDCEFLAALY 172
           +      Q    ++++GRV+ V +  SD +   +L+
Sbjct: 122 KDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLH 157


>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
          Length = 898

 Score = 28.5 bits (62), Expect = 3.9
 Identities = 16/37 (43%), Positives = 23/37 (62%), Gaps = 3/37 (8%)

Query: 45  DTSSEVLDELYRVTREYTQNKKEAEKIIKN---LIKT 78
           D+  E  D+L   T + TQ K+EA++I KN   +IKT
Sbjct: 404 DSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKT 440


>gi|140161498 hypothetical protein LOC23281 isoform a [Homo sapiens]
          Length = 1379

 Score = 28.5 bits (62), Expect = 3.9
 Identities = 14/25 (56%), Positives = 16/25 (64%)

Query: 3   SEAEESKEVATDVFNSKNLAVQAQK 27
           SEA ESKEV T V  ++NL   A K
Sbjct: 504 SEARESKEVTTSVAENRNLLENADK 528


>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
          Length = 983

 Score = 27.7 bits (60), Expect = 6.7
 Identities = 31/154 (20%), Positives = 65/154 (42%), Gaps = 20/154 (12%)

Query: 7   ESKEVATDV------FNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTRE 60
           E K   TD       +     +++++  +L   + +S+          +V  E+ ++  E
Sbjct: 777 EEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKE------KEKVHSEVVQIRSE 830

Query: 61  YTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVD 120
            +Q K+E E I   L     ++  L +  Q  Q+ELA M+++ +   +L        + D
Sbjct: 831 VSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKL--------EED 882

Query: 121 YTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGR 154
                N +S+ + + +E L+ + Q   +  S  R
Sbjct: 883 KDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKR 916


>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
          Length = 972

 Score = 27.7 bits (60), Expect = 6.7
 Identities = 31/154 (20%), Positives = 65/154 (42%), Gaps = 20/154 (12%)

Query: 7   ESKEVATDV------FNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTRE 60
           E K   TD       +     +++++  +L   + +S+          +V  E+ ++  E
Sbjct: 766 EEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKE------KEKVHSEVVQIRSE 819

Query: 61  YTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVD 120
            +Q K+E E I   L     ++  L +  Q  Q+ELA M+++ +   +L        + D
Sbjct: 820 VSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKL--------EED 871

Query: 121 YTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGR 154
                N +S+ + + +E L+ + Q   +  S  R
Sbjct: 872 KDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKR 905


>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
          Length = 951

 Score = 27.7 bits (60), Expect = 6.7
 Identities = 31/154 (20%), Positives = 65/154 (42%), Gaps = 20/154 (12%)

Query: 7   ESKEVATDV------FNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTRE 60
           E K   TD       +     +++++  +L   + +S+          +V  E+ ++  E
Sbjct: 745 EEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKE------KEKVHSEVVQIRSE 798

Query: 61  YTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVD 120
            +Q K+E E I   L     ++  L +  Q  Q+ELA M+++ +   +L        + D
Sbjct: 799 VSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKL--------EED 850

Query: 121 YTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGR 154
                N +S+ + + +E L+ + Q   +  S  R
Sbjct: 851 KDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKR 884


>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 27.7 bits (60), Expect = 6.7
 Identities = 31/154 (20%), Positives = 65/154 (42%), Gaps = 20/154 (12%)

Query: 7   ESKEVATDV------FNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTRE 60
           E K   TD       +     +++++  +L   + +S+          +V  E+ ++  E
Sbjct: 774 EEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKE------KEKVHSEVVQIRSE 827

Query: 61  YTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVD 120
            +Q K+E E I   L     ++  L +  Q  Q+ELA M+++ +   +L        + D
Sbjct: 828 VSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKL--------EED 879

Query: 121 YTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGR 154
                N +S+ + + +E L+ + Q   +  S  R
Sbjct: 880 KDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKR 913


>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 27.7 bits (60), Expect = 6.7
 Identities = 31/154 (20%), Positives = 65/154 (42%), Gaps = 20/154 (12%)

Query: 7   ESKEVATDV------FNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTRE 60
           E K   TD       +     +++++  +L   + +S+          +V  E+ ++  E
Sbjct: 774 EEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKE------KEKVHSEVVQIRSE 827

Query: 61  YTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVD 120
            +Q K+E E I   L     ++  L +  Q  Q+ELA M+++ +   +L        + D
Sbjct: 828 VSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKL--------EED 879

Query: 121 YTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGR 154
                N +S+ + + +E L+ + Q   +  S  R
Sbjct: 880 KDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKR 913


>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 27.7 bits (60), Expect = 6.7
 Identities = 31/154 (20%), Positives = 65/154 (42%), Gaps = 20/154 (12%)

Query: 7   ESKEVATDV------FNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTRE 60
           E K   TD       +     +++++  +L   + +S+          +V  E+ ++  E
Sbjct: 774 EEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKE------KEKVHSEVVQIRSE 827

Query: 61  YTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVD 120
            +Q K+E E I   L     ++  L +  Q  Q+ELA M+++ +   +L        + D
Sbjct: 828 VSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKL--------EED 879

Query: 121 YTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGR 154
                N +S+ + + +E L+ + Q   +  S  R
Sbjct: 880 KDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKR 913


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.132    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,131,181
Number of Sequences: 37866
Number of extensions: 229991
Number of successful extensions: 866
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 837
Number of HSP's gapped (non-prelim): 55
length of query: 198
length of database: 18,247,518
effective HSP length: 97
effective length of query: 101
effective length of database: 14,574,516
effective search space: 1472026116
effective search space used: 1472026116
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.