Guide to the Human Genome
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Search of human proteins with 10863977

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10863977 LSM2 homolog, U6 small nuclear RNA associated [Homo
sapiens]
         (95 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10863977 LSM2 homolog, U6 small nuclear RNA associated [Homo ...   190   2e-49
gi|6912486 U6 snRNA-associated Sm-like protein 4 [Homo sapiens]        48   1e-06
gi|14249632 LSM10, U7 small nuclear RNA associated [Homo sapiens]      45   1e-05
gi|5902102 small nuclear ribonucleoprotein D1 polypeptide 16kDa ...    39   7e-04
gi|169160654 PREDICTED: similar to small nuclear ribonucleoprote...    35   0.010
gi|7657315 Lsm3 protein [Homo sapiens]                                 35   0.017
gi|5901998 Sm protein F [Homo sapiens]                                 35   0.017
gi|4507131 small nuclear ribonucleoprotein polypeptide F [Homo s...    32   0.11 
gi|6912488 LSM5 homolog, U6 small nuclear RNA associated isoform...    28   1.2  
gi|116812595 3'(2'), 5'-bisphosphate nucleotidase 1 [Homo sapiens]     27   2.7  
gi|4759160 small nuclear ribonucleoprotein polypeptide D3 [Homo ...    26   6.0  
gi|4507693 tuberous sclerosis 1 protein isoform 1 [Homo sapiens]       26   7.8  
gi|241666464 tuberous sclerosis 1 protein isoform 4 [Homo sapiens]     26   7.8  
gi|241666462 tuberous sclerosis 1 protein isoform 3 [Homo sapiens]     26   7.8  

>gi|10863977 LSM2 homolog, U6 small nuclear RNA associated [Homo
          sapiens]
          Length = 95

 Score =  190 bits (483), Expect = 2e-49
 Identities = 95/95 (100%), Positives = 95/95 (100%)

Query: 1  MLFYSFFKSLVGKDVVVELKNDLSICGTLHSVDQYLNIKLTDISVTDPEKYPHMLSVKNC 60
          MLFYSFFKSLVGKDVVVELKNDLSICGTLHSVDQYLNIKLTDISVTDPEKYPHMLSVKNC
Sbjct: 1  MLFYSFFKSLVGKDVVVELKNDLSICGTLHSVDQYLNIKLTDISVTDPEKYPHMLSVKNC 60

Query: 61 FIRGSVVRYVQLPADEVDTQLLQDAARKEALQQKQ 95
          FIRGSVVRYVQLPADEVDTQLLQDAARKEALQQKQ
Sbjct: 61 FIRGSVVRYVQLPADEVDTQLLQDAARKEALQQKQ 95


>gi|6912486 U6 snRNA-associated Sm-like protein 4 [Homo sapiens]
          Length = 139

 Score = 48.1 bits (113), Expect = 1e-06
 Identities = 28/80 (35%), Positives = 46/80 (57%), Gaps = 5/80 (6%)

Query: 1  MLFYSFFKSLVGKDVVVELKNDLSICGTLHSVDQYLNIKLTDISVT--DPEKYPHMLSVK 58
          ML  S  K+     ++VELKN  +  G L S D ++NI L ++  T  D +K+  M    
Sbjct: 1  MLPLSLLKTAQNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDKFWRM---P 57

Query: 59 NCFIRGSVVRYVQLPADEVD 78
           C+IRGS ++Y+++P + +D
Sbjct: 58 ECYIRGSTIKYLRIPDEIID 77


>gi|14249632 LSM10, U7 small nuclear RNA associated [Homo sapiens]
          Length = 123

 Score = 45.4 bits (106), Expect = 1e-05
 Identities = 21/68 (30%), Positives = 41/68 (60%), Gaps = 2/68 (2%)

Query: 8  KSLVGKDVVVELKNDLSICGTLHSVDQYLNIKLTDISVTDPEKYPHMLSVKNCFIRGSVV 67
          + L G+   V+L+++    G + +VD ++NI+L  ++ TD  ++ H + + + F+ G  V
Sbjct: 22 QGLQGRVTTVDLRDESVAHGRIDNVDAFMNIRLAKVTYTD--RWGHQVKLDDLFVTGRNV 79

Query: 68 RYVQLPAD 75
          RYV +P D
Sbjct: 80 RYVHIPDD 87


>gi|5902102 small nuclear ribonucleoprotein D1 polypeptide 16kDa
          [Homo sapiens]
          Length = 119

 Score = 39.3 bits (90), Expect = 7e-04
 Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 1  MLFYSFFKSLVGKDVVVELKNDLSICGTLHSVDQYLNIKLTDISVTDPEKYPHMLSVKNC 60
          M    F   L  + V +ELKN   + GT+  VD  +N  L  + +T   + P  + ++  
Sbjct: 1  MKLVRFLMKLSHETVTIELKNGTQVHGTITGVDVSMNTHLKAVKMTLKNREP--VQLETL 58

Query: 61 FIRGSVVRYVQLPADEVDTQLLQDAARKEALQQKQ 95
           IRG+ +RY  LP       LL D   K   ++++
Sbjct: 59 SIRGNNIRYFILPDSLPLDTLLVDVEPKVKSKKRE 93


>gi|169160654 PREDICTED: similar to small nuclear
          ribonucleoprotein D1 polypeptide 16kDa [Homo sapiens]
          Length = 119

 Score = 35.4 bits (80), Expect = 0.010
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 8/97 (8%)

Query: 1  MLFYSFFKSLVGKDVVVELKNDLSICGTLHSVDQYLNIKLTDISVTDPEKYPHMLSVKNC 60
          M    F   L  + V + LKN   + GT+  VD  +N  L  + +T   + P  + ++  
Sbjct: 1  MKLVRFLMKLSHETVTIALKNRTQVHGTVTGVDVSMNTHLKAVKMTPKNREP--VQLETL 58

Query: 61 FIRGSVVRYV----QLPADE--VDTQLLQDAARKEAL 91
           IRG+ +RY      LP D   VD +    + ++EA+
Sbjct: 59 SIRGNNIRYFILLDSLPLDTLLVDVEPKVKSKKREAV 95


>gi|7657315 Lsm3 protein [Homo sapiens]
          Length = 102

 Score = 34.7 bits (78), Expect = 0.017
 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 11/70 (15%)

Query: 15 VVVELKNDLSICGTLHSVDQYLNIKLTDISVT------DPEKYPHML-----SVKNCFIR 63
          + V+++ND  + G LH+ DQ+LN+ L D+  T      D E Y  +      ++   F+R
Sbjct: 29 IYVKMRNDRELRGRLHAYDQHLNMILGDVEETVTTIEIDEETYEEIYKSTKRNIPMLFVR 88

Query: 64 GSVVRYVQLP 73
          G  V  V  P
Sbjct: 89 GDGVVLVAPP 98


>gi|5901998 Sm protein F [Homo sapiens]
          Length = 80

 Score = 34.7 bits (78), Expect = 0.017
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 6/67 (8%)

Query: 6  FFKSLVGKDVVVELKNDLSICGTLHSVDQYLNIKL--TDISVTDPEKYPHMLSVKNCFIR 63
          F K ++G+ VVV+L + +   G L  +D Y+NI L  T+  V    K  +     + FIR
Sbjct: 11 FLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKY----GDAFIR 66

Query: 64 GSVVRYV 70
          G+ V Y+
Sbjct: 67 GNNVLYI 73


>gi|4507131 small nuclear ribonucleoprotein polypeptide F [Homo
          sapiens]
          Length = 86

 Score = 32.0 bits (71), Expect = 0.11
 Identities = 16/37 (43%), Positives = 23/37 (62%)

Query: 6  FFKSLVGKDVVVELKNDLSICGTLHSVDQYLNIKLTD 42
          F   L GK V+V+LK  +   G L SVD Y+N++L +
Sbjct: 10 FLNGLTGKPVMVKLKWGMEYKGYLVSVDGYMNMQLAN 46


>gi|6912488 LSM5 homolog, U6 small nuclear RNA associated isoform
          a [Homo sapiens]
          Length = 91

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 11/34 (32%), Positives = 21/34 (61%)

Query: 11 VGKDVVVELKNDLSICGTLHSVDQYLNIKLTDIS 44
          +G  + + +K+D  I GTL   D ++N+ L D++
Sbjct: 22 IGSRIHIVMKSDKEIVGTLLGFDDFVNMVLEDVT 55


>gi|116812595 3'(2'), 5'-bisphosphate nucleotidase 1 [Homo
          sapiens]
          Length = 308

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 12/38 (31%), Positives = 25/38 (65%)

Query: 56 SVKNCFIRGSVVRYVQLPADEVDTQLLQDAARKEALQQ 93
          S+   F + +++    LP++EVD +L++D+  +E L+Q
Sbjct: 61 SLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQ 98


>gi|4759160 small nuclear ribonucleoprotein polypeptide D3 [Homo
          sapiens]
          Length = 126

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 16/68 (23%), Positives = 38/68 (55%), Gaps = 8/68 (11%)

Query: 27 GTLHSVDQYLNIKLTDISVTDPEKYPHMLSVKNCFIRGSVVRYVQLPADEVDTQLLQDAA 86
          G L   +  +N ++++I+VT  +    +  ++  +IRGS +R++ LP       +L++A 
Sbjct: 30 GKLIEAEDNMNCQMSNITVTYRDG--RVAQLEQVYIRGSKIRFLILP------DMLKNAP 81

Query: 87 RKEALQQK 94
            ++++ K
Sbjct: 82 MLKSMKNK 89


>gi|4507693 tuberous sclerosis 1 protein isoform 1 [Homo sapiens]
          Length = 1164

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 12/31 (38%), Positives = 16/31 (51%)

Query: 33  DQYLNIKLTDISVTDPEKYPHMLSVKNCFIR 63
           D Y++I L   +VT P K   M S + C  R
Sbjct: 404 DDYVHISLPQATVTPPRKEERMDSARPCLHR 434


>gi|241666464 tuberous sclerosis 1 protein isoform 4 [Homo sapiens]
          Length = 1113

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 12/31 (38%), Positives = 16/31 (51%)

Query: 33  DQYLNIKLTDISVTDPEKYPHMLSVKNCFIR 63
           D Y++I L   +VT P K   M S + C  R
Sbjct: 353 DDYVHISLPQATVTPPRKEERMDSARPCLHR 383


>gi|241666462 tuberous sclerosis 1 protein isoform 3 [Homo sapiens]
          Length = 1163

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 12/31 (38%), Positives = 16/31 (51%)

Query: 33  DQYLNIKLTDISVTDPEKYPHMLSVKNCFIR 63
           D Y++I L   +VT P K   M S + C  R
Sbjct: 403 DDYVHISLPQATVTPPRKEERMDSARPCLHR 433


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,090,671
Number of Sequences: 37866
Number of extensions: 105001
Number of successful extensions: 254
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 239
Number of HSP's gapped (non-prelim): 14
length of query: 95
length of database: 18,247,518
effective HSP length: 66
effective length of query: 29
effective length of database: 15,748,362
effective search space: 456702498
effective search space used: 456702498
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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