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Search of human proteins with 239749449
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
(275 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 541 e-154
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 273 9e-74
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 158 6e-39
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 148 4e-36
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 145 4e-35
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 141 7e-34
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 138 5e-33
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 134 1e-31
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 127 8e-30
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 127 1e-29
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 127 1e-29
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 122 4e-28
gi|148746195 trichohyalin [Homo sapiens] 120 2e-27
gi|52426743 cisplatin resistance-associated overexpressed protei... 118 6e-27
gi|19923485 cisplatin resistance-associated overexpressed protei... 118 6e-27
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 111 6e-25
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 111 8e-25
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 110 1e-24
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 108 5e-24
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 107 1e-23
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 106 3e-23
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 104 7e-23
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 104 7e-23
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 104 1e-22
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 103 1e-22
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 103 2e-22
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 102 5e-22
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 102 5e-22
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 102 5e-22
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 102 5e-22
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 541 bits (1394), Expect = e-154
Identities = 275/275 (100%), Positives = 275/275 (100%)
Query: 1 MVKAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGK 60
MVKAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGK
Sbjct: 1 MVKAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGK 60
Query: 61 KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER 120
KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER
Sbjct: 61 KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER 120
Query: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180
KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180
Query: 181 KERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVFRYR 240
KERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVFRYR
Sbjct: 181 KERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVFRYR 240
Query: 241 IFHTGLDHFPIKTNILLSRHEVNDGEIEVNDGEML 275
IFHTGLDHFPIKTNILLSRHEVNDGEIEVNDGEML
Sbjct: 241 IFHTGLDHFPIKTNILLSRHEVNDGEIEVNDGEML 275
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 273 bits (699), Expect = 9e-74
Identities = 148/235 (62%), Positives = 185/235 (78%), Gaps = 29/235 (12%)
Query: 1 MVKAISSRAAVKLNTELQMVSCSHISKPCTQ-----------------------RESERK 37
MVKAISSRAAVKLNTELQMVSCSHISKPCTQ RESERK
Sbjct: 1 MVKAISSRAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERK 60
Query: 38 KERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKR 97
KERREREKRKREREKERKRERGKKEKK +K+E ERERK++ REK+ KE EKE+RK
Sbjct: 61 KERREREKRKREREKERKRERGKKEKKGERKKE---ERERKKRRREKENKEGEEKEKRK- 116
Query: 98 KKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRE 157
KKEKK+R R + +ER++K+ERK ER+ ++R++ +R+K R++K RK+R+R K+ G++E
Sbjct: 117 KKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRER-KQVGEKE 175
Query: 158 RKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTD 212
+RK+++++ER KKRERNRKERKKERERKERRERKKERKK+ +KKER+KDR+T+
Sbjct: 176 EERKEKERKER-KKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTN 229
Score = 90.1 bits (222), Expect = 2e-18
Identities = 50/131 (38%), Positives = 89/131 (67%), Gaps = 9/131 (6%)
Query: 108 QRGRRERKKKKERK-ERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKE 166
Q G + +++ER+ E +E K+ RE +RKK R+++ +++R+REKER KRER +K++K E
Sbjct: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKER-KRERGKKEKKGE 89
Query: 167 EREKKRERNRKERKKE-RERKERRERKKERKKER------RKKKERKKDRKTDRQTDSQV 219
++++RER ++ R+KE +E +E+ +RKK+ KKER K++ERK++RK + + + +
Sbjct: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149
Query: 220 FRPLRESAFNR 230
+ RE R
Sbjct: 150 KKEEREKERER 160
Score = 65.1 bits (157), Expect = 6e-11
Identities = 36/110 (32%), Positives = 67/110 (60%), Gaps = 13/110 (11%)
Query: 131 RERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRE 190
RER+R+ +K+ +KER+ E+++ +RER+++KR++E KERK+ER +KE+
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKRERE----------KERKRERGKKEK-- 86
Query: 191 RKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVFRYR 240
K ERKKE R++K+R+++++ + + + + R + G R R
Sbjct: 87 -KGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER 135
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 158 bits (399), Expect = 6e-39
Identities = 85/196 (43%), Positives = 143/196 (72%), Gaps = 15/196 (7%)
Query: 31 QRESERKKER-REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRK-----EREK 84
QR++ER +++ REREK ++ER +ER+R+R K+ K + + ERG+ERER+R+ ER++
Sbjct: 168 QRQTERNRQKEREREKNRQER-RERERQREKENKTEDRHSERGRERERERETETETERKR 226
Query: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR-----R 139
Q R+++R+ ++ +K+ ER++ RE ++ KER ERER+ + R+R++K+R R
Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDKER-ERERDRDRDRDRRQKERERQTDR 285
Query: 140 KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER 199
K++RR ER RE ER KRER+R++ ++ ER +KRER R ER++ERER+ ER +E+++ER
Sbjct: 286 KRQRRTERDRETER-KRERQRERERERERNRKRERER-ERERERERQRETERDREKERER 343
Query: 200 RKKKERKKDRKTDRQT 215
++K++ + DR+ +RQT
Sbjct: 344 KRKRQTEMDRERNRQT 359
Score = 155 bits (393), Expect = 3e-38
Identities = 85/215 (39%), Positives = 143/215 (66%), Gaps = 21/215 (9%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRK-----EREKQ 85
Q+E ER+K R+ER +R+R+REKE K E E+ + ++RER E E +RK ER++Q
Sbjct: 176 QKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQ 235
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKER------KERERENKQRRERKRKKRR 139
RK RE+E++ ++ +RE ++ RER++ ++R KERER+ ++R+R+ ++ R
Sbjct: 236 RKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDR 295
Query: 140 KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNR---KERKKERERKER------RE 190
+ +R++ER+RE+ER +RER RK+ ++ ERE++RER R ++R+KERERK + RE
Sbjct: 296 ETERKRERQRERER-ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE 354
Query: 191 RKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
R ++ +E R++ ER+++R+ +R S R RE
Sbjct: 355 RNRQTGREGRRQAERERERERERDRQSAREREERE 389
Score = 155 bits (391), Expect = 5e-38
Identities = 82/197 (41%), Positives = 138/197 (70%), Gaps = 9/197 (4%)
Query: 32 RESERKKER-REREKRKREREKERKRERGKKEKKKRKKRERGKERERKR-KEREKQRKER 89
RE R+KER R REKR+ ERE +RKRER ++EK + +KR+R +ER+R R KERE+Q
Sbjct: 54 RERNRQKERERRREKRQTERETDRKRER-RREKDRHRKRDRHRERQRDREKERERQTDRE 112
Query: 90 REKERRKRKKEKKKRERKQRGRRERKKKKE---RKERERENKQRRERKRKKRRKKKRRKE 146
R+++R K + +K+RER+ ER + ++ ++ERER+ +ER+R+ R+++R+ E
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172
Query: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
R R+KER +RE+ R++R++ ER++++E ++R ER R+ RER+ E + ER+++ +R+
Sbjct: 173 RNRQKER-EREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
Query: 207 KD--RKTDRQTDSQVFR 221
+D RKT+R+ + Q R
Sbjct: 232 RDRQRKTEREREKQAER 248
Score = 153 bits (387), Expect = 1e-37
Identities = 85/210 (40%), Positives = 147/210 (70%), Gaps = 25/210 (11%)
Query: 32 RESERKKERREREKRKREREKERKRERG-KKEKKKRKKRERGKERERKR-KEREKQRKER 89
RE ER++E +RKR+ ++ER R+R ++E++K+ +RER ERE +R KERE++R
Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269
Query: 90 REKERRKRKKEK---KKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
R+++RR++++E+ +KR+R+ RE ++K+ER +RERE ++ R RKR++ R+++R +E
Sbjct: 270 RDRDRRQKERERQTDRKRQRRTERDRETERKRER-QRERERERERNRKRERERERERERE 328
Query: 147 RKREKERGKRERKRKKRKKEEREKKRERNR-----------KERKKERER-----KERRE 190
R+RE ER RE++R++++K + E RERNR +ER++ERER +ER E
Sbjct: 329 RQRETERD-REKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE 387
Query: 191 RKKERKKERRKKKER--KKDRKTDRQTDSQ 218
R+++R ++R+K++ER +KDR R+T+ Q
Sbjct: 388 RERDRDRDRQKERERQTEKDRDGQRETEKQ 417
Score = 151 bits (381), Expect = 7e-37
Identities = 82/224 (36%), Positives = 147/224 (65%), Gaps = 27/224 (12%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKER------- 82
T+RE E++ ER +R+ ER+KER+RER + + R+++ER ++ +RKR+ R
Sbjct: 238 TEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRET 297
Query: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER---KERERENKQR----RERKR 135
E++R+ +RE+ER + + K++RER++ RER+++ ER KERER+ K++ RER R
Sbjct: 298 ERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNR 357
Query: 136 KKRRKKKRRKERKREKERGK----------RERKRKKRKKEEREKKRERNR---KERKKE 182
+ R+ +R+ ER+RE+ER + RER R + +++ERE++ E++R +E +K+
Sbjct: 358 QTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ 417
Query: 183 RERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRES 226
RER++ RE ++ R++ R ++K++ ++R +RQTD Q R + S
Sbjct: 418 REREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRS 461
Score = 150 bits (380), Expect = 9e-37
Identities = 70/206 (33%), Positives = 144/206 (69%), Gaps = 19/206 (9%)
Query: 30 TQRESERKKERREREKRKREREKERKRERG-----KKEKKKRKKRERGKERERKRKEREK 84
T+R+ + +ER + K +REREK+ +RER +++K++ ++R+R ++R+R++KERE+
Sbjct: 222 TERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERER 281
Query: 85 Q--RKERREKERRKRKKEKKKRERKQRGRRERKKKKER---KERERENKQRRERKRKKRR 139
Q RK +R ER + + K++R+R++ RER +K+ER +ERERE ++ ER R+K R
Sbjct: 282 QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKER 341
Query: 140 KKKRRKERKREKERGKR---------ERKRKKRKKEEREKKRERNRKERKKERERKERRE 190
++KR+++ + ++ER ++ ER+R++ ++ +R+ RER +ER ++R+R++ RE
Sbjct: 342 ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERE 401
Query: 191 RKKERKKERRKKKERKKDRKTDRQTD 216
R+ E+ ++ +++ E++++R+ DR+++
Sbjct: 402 RQTEKDRDGQRETEKQREREKDRESE 427
Score = 149 bits (377), Expect = 2e-36
Identities = 81/230 (35%), Positives = 145/230 (63%), Gaps = 41/230 (17%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGK-----------------KEKKKRKKRERG 72
T RE +R++E+ +++RERE ER+ ERG+ KE++++ RER
Sbjct: 109 TDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ 168
Query: 73 KERER---KRKEREKQRKERREKERRKRKKEKKKRERKQRGRR-----------ERKKKK 118
++ ER K +EREK R+ERRE+ER++ K+ K + +RGR ERK++
Sbjct: 169 RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQT 228
Query: 119 ERK-------ERERENKQRRER--KRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE 169
+R+ ERERE + RER +R+ R K+R +ER R+++R +R+++R+++ +R+
Sbjct: 229 DRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQ 288
Query: 170 KKRERNRK-ERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
++ ER+R+ ERK+ER+R+ RER++ RK+ER +++ER+++R+ + + D +
Sbjct: 289 RRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDRE 338
Score = 147 bits (371), Expect = 1e-35
Identities = 76/199 (38%), Positives = 141/199 (70%), Gaps = 13/199 (6%)
Query: 31 QRESERKKERREREKRKREREKERKRERGK-KEKKKRKKRERGKERERKRKEREKQRKER 89
QR++E+++ER+ +R+R+ E+ R++ER + K +++R++RER +E+E K ++R +R
Sbjct: 152 QRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRE 211
Query: 90 REKERRKRKKEKKKRERKQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKRRKERK 148
RE+ER + ++KR+ + R+RK ++ER K+ ERE RE +R K R+++R ++R
Sbjct: 212 RERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRD 271
Query: 149 REKERGKRERK--RKKRKKEER----EKKRERNR-KERKKERERKERRERKKERKKERRK 201
R++ + +RER+ RK++++ ER E+KRER R +ER++ER RK RER++ER++ER++
Sbjct: 272 RDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR 331
Query: 202 K----KERKKDRKTDRQTD 216
+ +E++++RK RQT+
Sbjct: 332 ETERDREKERERKRKRQTE 350
Score = 146 bits (369), Expect = 2e-35
Identities = 77/201 (38%), Positives = 143/201 (71%), Gaps = 17/201 (8%)
Query: 31 QRESERKKERREREK---RKREREKERKRERGKKEKKKRKKRERGKERER-----KRKER 82
Q+E ER++E+R+ E+ RKRER +E+ R R K+++ + ++R+R KERER + ++R
Sbjct: 59 QKERERRREKRQTERETDRKRERRREKDRHR-KRDRHRERQRDREKERERQTDRERDRQR 117
Query: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKE-RKERERENKQRRERKRKKRRKK 141
EK+R ++E+ER ++ ++ R+R+ G+RER+++++ KERER+ + R+R+ ++ R+K
Sbjct: 118 EKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQK 177
Query: 142 KRRKERKREKERGKRERKRKKRKK-----EEREKKRERNRK-ERKKERERKERRERKKER 195
+R +E+ R+ ER +RER+R+K K ER ++RER R+ E + ER+R+ RER ++R
Sbjct: 178 EREREKNRQ-ERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQR 236
Query: 196 KKERRKKKERKKDRKTDRQTD 216
K ER ++K+ +++R ++R+T+
Sbjct: 237 KTEREREKQAERERASERETE 257
Score = 146 bits (369), Expect = 2e-35
Identities = 71/213 (33%), Positives = 146/213 (68%), Gaps = 10/213 (4%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGK-KEKKKRKKRERGKERERKR---KEREKQ 85
T+RE++RK+ERR + R R+R++ R+R+R + KE++++ RER ++RE++R KERE++
Sbjct: 71 TERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERE 130
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKRR 144
+ E+ R ++ +++RER++ +ER+++ +R ++R+ E +++ER+R+K R+++R
Sbjct: 131 TEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRE 190
Query: 145 KERKREKERGKRERKRKKRKKEEREKKRE-----RNRKERKKERERKERRERKKERKKER 199
+ER+REKE +R ++ ++ ERE++ E + + +R+++R+RK RER+K+ ++ER
Sbjct: 191 RERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERER 250
Query: 200 RKKKERKKDRKTDRQTDSQVFRPLRESAFNRVT 232
++E ++D++ +R+ D R R+ R T
Sbjct: 251 ASERETERDKERERERDRDRDRDRRQKERERQT 283
Score = 141 bits (355), Expect = 7e-34
Identities = 83/215 (38%), Positives = 145/215 (67%), Gaps = 31/215 (14%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKR--ERG--------KERERKR- 79
QR+ E+++ER+ +R R+REKER R+ KE+++ +R ERG +ERER+R
Sbjct: 98 QRDREKERERQTDRERDRQREKERNRQ---KERERETEREGERGRDRQTDGQRERERQRD 154
Query: 80 --KEREKQ--RKERREKERRKRKKEKKKRERKQRGRRERKKKKERK----------ERER 125
KERE+Q R+ +R+ ER ++K+ ++++ R++R RER+++KE K ERER
Sbjct: 155 AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER 214
Query: 126 ENKQRRERKRKKRRKKKRRKERKREKERGKR-ERKRKKRKKEEREKKRERNR-KERKKER 183
E + E +RK++ ++R ++RK E+ER K+ ER+R ++ ER+K+RER R ++R ++R
Sbjct: 215 ERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDR 274
Query: 184 ERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
+KE RER+ +RK++RR +++R+ +RK +RQ + +
Sbjct: 275 RQKE-RERQTDRKRQRRTERDRETERKRERQRERE 308
Score = 132 bits (333), Expect = 3e-31
Identities = 70/197 (35%), Positives = 133/197 (67%), Gaps = 21/197 (10%)
Query: 46 RKREREKERKRERGKKEKKKR-----KKRERGKERERKRKEREKQRKERREKERRKRKKE 100
R+R +E R RG + K ++R R KERER+R++R+ +R+ R++ERR+ K
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
Query: 101 KKKRERKQRGRRERKKKKERK-ERERENKQRRERKRKKRRKKKRRKERKREKER---GKR 156
+KR+R + +R+R+K++ER+ +RER+ ++ +ER R+K R+++ +E +R ++R G+R
Sbjct: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR 147
Query: 157 ERKRKKRKKEEREKKRERNR---------KERKKERERKERRERKKERKKERR---KKKE 204
ER+R++ ++ERE++ +R R KER++E+ R+ERRER+++R+KE + + E
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE 207
Query: 205 RKKDRKTDRQTDSQVFR 221
R ++R+ +R+T+++ R
Sbjct: 208 RGRERERERETETETER 224
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 148 bits (374), Expect = 4e-36
Identities = 72/187 (38%), Positives = 135/187 (72%), Gaps = 8/187 (4%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERER-----KRKEREKQ 85
+R+ ERK+E ++ +RER+++R+RE + + + ++R+R +ER+R K +ER+K+
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKRR 144
R +R++ER ++ +++RER+++ R+R+ +ER K+R+RE K+ +R R++ RK R
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
Query: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK-KK 203
++++ E+ER RER+R+++++ ER+++RER R+ ++ + ER ERKKERKKER+K +K
Sbjct: 122 RDKQTERER-DRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK 180
Query: 204 ERKKDRK 210
E+KK+ K
Sbjct: 181 EKKKEEK 187
Score = 147 bits (372), Expect = 8e-36
Identities = 71/183 (38%), Positives = 140/183 (76%), Gaps = 9/183 (4%)
Query: 30 TQRESERKKERR---EREKRKREREKERKRERGKKEKKKRKKRERGKERERKR-KEREKQ 85
T+RE +R++ER ERE R R+R++ R+R+R + + K+RER KER+R+R +ERE +
Sbjct: 17 TERERDRQRERENQTERENRHRQRDRHRERDR---QTDREKERERQKERDRQRQRERETE 73
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKRR 144
R+ R++ER+++++ K++ +R++ R+R++K+E + RER K RER ++ R++ R
Sbjct: 74 RETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRE 133
Query: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE 204
+ER+R++ER +R+R+R+++++ +RE++R R+ERKKER+++ ++ERK+++K+E+R++ +
Sbjct: 134 RERQRQRER-ERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDK 192
Query: 205 RKK 207
++K
Sbjct: 193 KRK 195
Score = 147 bits (371), Expect = 1e-35
Identities = 78/190 (41%), Positives = 138/190 (72%), Gaps = 9/190 (4%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERG----KERER-KRKEREKQ 85
+RE++R KE R+RERE + +RE +++ + ++R+R KERER K ++R++Q
Sbjct: 8 KRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQ 67
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
R+ E+E ++++ +++RERK++ RER K ++R ER+RE + RER RK R++ ++
Sbjct: 68 RERETERETERQRERQRQRERKRQTDRERDKDRDR-ERKRETDRNRERNRKGGRERDKQT 126
Query: 146 ERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER-RERKKERKKERRKKKE 204
ER+R++ER +R+R+R++ ++ +RE+KRE +R ER++ ER+ER +ERKKERKKER++KK+
Sbjct: 127 ERERDRER-ERQRQRERERQRQRERKRETDR-ERQRWAEREERKKERKKERKKERKEKKK 184
Query: 205 RKKDRKTDRQ 214
+K R+ ++
Sbjct: 185 EEKRREDKKR 194
Score = 123 bits (308), Expect = 2e-28
Identities = 59/172 (34%), Positives = 122/172 (70%), Gaps = 10/172 (5%)
Query: 49 EREKERKRERGK-KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERK 107
ER++ERKRE + KE ++ + R+R +E + +R+ R +QR RE++R+ ++++++R+++
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 108 QRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEE 167
+ +R+R ERE E + R+R+R+++R++KR+ +R+R+K+R RERKR+ + E
Sbjct: 62 RDRQRQR-------ERETERETERQRERQRQRERKRQTDRERDKDRD-RERKRETDRNRE 113
Query: 168 REKKRERNR-KERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
R +K R R K+ ++ER+R+ R+R++ER+++R+++++R+ DR+ R + +
Sbjct: 114 RNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE 165
Score = 81.3 bits (199), Expect = 9e-16
Identities = 41/112 (36%), Positives = 79/112 (70%), Gaps = 6/112 (5%)
Query: 111 RRERKKKKER-KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE 169
+RERK++ +R KE ERE ++RER+ + R+ + R +R R +ER +R+ + K+ ER+
Sbjct: 4 QRERKRETDRGKETERERDRQRERENQTERENRHR-QRDRHRER---DRQTDREKERERQ 59
Query: 170 KKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFR 221
K+R+R R +R++E ER+ R+R+++R++ER+++ +R++D+ DR+ + R
Sbjct: 60 KERDRQR-QRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDR 110
Score = 76.3 bits (186), Expect = 3e-14
Identities = 45/114 (39%), Positives = 79/114 (69%), Gaps = 8/114 (7%)
Query: 122 ERERENKQRRERKRKKRRKKKRRKER--KREKE--RGKRERKRKKRKKEEREKKRERNRK 177
ER+RE K+ +R ++ R++ R++ER + E+E +R+R R++ ++ +REK+RER +K
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERER-QK 60
Query: 178 ERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRP-LRESAFNR 230
ER ++R+R+ ER+ ER++ER++++ERK R+TDR+ D R RE+ NR
Sbjct: 61 ERDRQRQRERETERETERQRERQRQRERK--RQTDRERDKDRDRERKRETDRNR 112
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 145 bits (366), Expect = 4e-35
Identities = 75/199 (37%), Positives = 139/199 (69%), Gaps = 12/199 (6%)
Query: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
K + + +++KER+E EK +RERE+ER+RER ++E+++ ++RER +E+E KERE++R
Sbjct: 289 KKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKE---KERERER 345
Query: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
+ R+++R K + + RER + RER + K+R R ++ R+R+R++ R+++R +E
Sbjct: 346 ERDRDRDRTKERDRDRDRERDRDRDRERSSDRN-KDRSRSREKSRDRERERERERERERE 404
Query: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKK---ERERKERRERKKERKKERRKK- 202
R+RE+ER +RER+R++ ++ EREK ++R+R+E ++ ER + ER+ R+KE + R K
Sbjct: 405 RERERER-EREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKN 463
Query: 203 ---KERKKDRKTDRQTDSQ 218
+ERKK R+ +++ + +
Sbjct: 464 WEIRERKKTREYEKEAERE 482
Score = 144 bits (364), Expect = 6e-35
Identities = 81/209 (38%), Positives = 140/209 (66%), Gaps = 10/209 (4%)
Query: 31 QRESERKKERREREK---RKREREKERKRERGK---KEKKKRKKRERGKERERKRKEREK 84
+RE ER++ERRERE+ R+REREKE++RER + +++ + K+R+R ++RER R +R++
Sbjct: 313 ERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDR-DRDR 371
Query: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKR 143
+R R K+R + +++ + RER++ RER++++ER +ERERE ++ RER+R++ + KKR
Sbjct: 372 ERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKR 431
Query: 144 RKERKREKERGKRERKRKKRKKEEREKKRERN--RKERKKERERKERRERKKERKKERRK 201
+E E +R+ +RK R+KE ++R +N +ERKK RE ++ ER++ER++E K
Sbjct: 432 DREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAK 491
Query: 202 KKERKKDRKTDRQTDSQVFRPLRESAFNR 230
+ +R K+ D D + R SA +
Sbjct: 492 EAKRLKEFLEDYDDDRDDPKYYRGSALQK 520
Score = 143 bits (360), Expect = 2e-34
Identities = 72/198 (36%), Positives = 133/198 (67%), Gaps = 18/198 (9%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR-KEREKQRKER 89
++E ER++ +ER +R+RERE+ER+R ++E+++ ++RE+ KERER+R ++R++ R +
Sbjct: 297 KKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKE 356
Query: 90 REKERRKRKKEKKKRERKQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKRRKERK 148
R+++R + + + RER ++R + +E+ ++RERE ++ RER+R++ R+++R +ER+
Sbjct: 357 RDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERE 416
Query: 149 REKERGKRERKRKKRKKEERE----KKRERNRKERKKE------------RERKERRERK 192
RE+ER + K KKR +EE E ++R+ RK R+KE RERK+ RE +
Sbjct: 417 REREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYE 476
Query: 193 KERKKERRKKKERKKDRK 210
KE ++E +++E K+ K
Sbjct: 477 KEAEREEERRREMAKEAK 494
Score = 139 bits (351), Expect = 2e-33
Identities = 73/173 (42%), Positives = 123/173 (71%), Gaps = 10/173 (5%)
Query: 52 KERKRERGKKEKKKRKKRERGKERERKRKEREKQR--KERREKER-RKRKKEKKKRERKQ 108
+E KR+ +E K + + E E+ +KE+E+Q KERRE+ER R+R++E+++RER++
Sbjct: 270 EEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERER 329
Query: 109 RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGK---RERKRKKRKK 165
RER+K+KER ERERE + R+R +++ R + R ++R R++ER ++R R + K
Sbjct: 330 EREREREKEKER-ERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKS 388
Query: 166 EEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
+RE++RER ER++ERER+ RER++ER++ER +++ER+KD+K DR+ D +
Sbjct: 389 RDRERERER---EREREREREREREREREREREREREREREKDKKRDREEDEE 438
Score = 136 bits (343), Expect = 2e-32
Identities = 73/184 (39%), Positives = 127/184 (69%), Gaps = 12/184 (6%)
Query: 35 ERKKERREREKRK-REREKERKRERGKKEK------KKRKKRERGKERERKRKEREKQRK 87
E K++ RE K R+ K+ + E+GKKEK K+R++RER +ERER+R+ERE++R+
Sbjct: 271 EDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERE 330
Query: 88 ERREKERRKRKKEKKKRERKQRGRRERKKKKER---KERERENKQRRERKRKKRRKKKRR 144
RE+E+ K ++ +++R+R + +ER + ++R ++R+RE R + R + R+K R
Sbjct: 331 REREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRD 390
Query: 145 KERKREKERGK-RERKRKKRKKEEREKKRERNR-KERKKERERKERRERKKERKKERRKK 202
+ER+RE+ER + RER+R++ ++ ERE++RER R +E+ K+R+R+E E ER+K RK
Sbjct: 391 REREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKL 450
Query: 203 KERK 206
+E++
Sbjct: 451 REKE 454
Score = 119 bits (297), Expect = 4e-27
Identities = 75/236 (31%), Positives = 127/236 (53%), Gaps = 44/236 (18%)
Query: 32 RESERKKERREREKRKREREKERKRERGK-KEKKKRKKRERGKERERKRKEREKQRKERR 90
RE R +ER +R+RERE+ER+RER + +E+++ ++RER K+++R R+E E+ ERR
Sbjct: 385 REKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERR 444
Query: 91 EKERRKRKKEKKKRERKQRGR-RERKKKKE-RKERERENKQRRERKRKKRRKK------- 141
+ ER+ R+KE +ER + RERKK +E KE ERE ++RRE ++ +R K
Sbjct: 445 KLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYD 504
Query: 142 ---------------KRRKERKREKERGKRERKRKKRKKEE------------------- 167
KR ++R++E E +R+RKR+K + EE
Sbjct: 505 DDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQR 564
Query: 168 REKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPL 223
E++ ER R+ + K+ E E +K+ K+E+R++ +++ + RP+
Sbjct: 565 MEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPI 620
Score = 118 bits (295), Expect = 6e-27
Identities = 74/219 (33%), Positives = 127/219 (57%), Gaps = 37/219 (16%)
Query: 31 QRESERKKER-REREK-------------RKREREKERKRERGKKEKKKRKKRERGKERE 76
+RE E++KER RERE+ R RER+++R RER ++ K + R R K R+
Sbjct: 332 EREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRER-SSDRNKDRSRSREKSRD 390
Query: 77 RKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK 136
R+R ERE++R+ RE+ER + ++ +++RER++ RE+ KK++R+E E + +RR+ +RK
Sbjct: 391 RER-EREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERK 449
Query: 137 KRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERN-RKERKKERE----------- 184
R K+ +ER + E +R++ R+ K+ ERE++R R KE K+ +E
Sbjct: 450 LREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDD 509
Query: 185 ---------RKERRERKKERKKERRKKKERKKDRKTDRQ 214
+K R+R+KE + + R +K K++ + RQ
Sbjct: 510 PKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQ 548
Score = 86.7 bits (213), Expect = 2e-17
Identities = 57/221 (25%), Positives = 118/221 (53%), Gaps = 53/221 (23%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERE---------RKRKE 81
+RE ER++ER +R+RERE+ER+RER ++E++K KKR+R ++ E RK +E
Sbjct: 394 ERERERERERERERERERERERERERER-EREREKDKKRDREEDEEDAYERRKLERKLRE 452
Query: 82 RE------------KQRKERREKERRKRKKEKKKRERKQRGRR----------------- 112
+E ++RK+ RE E+ ++E+++RE + +R
Sbjct: 453 KEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKY 512
Query: 113 -----------ERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRK 161
+R+K+ E ER+R+ ++ + ++R + + E +R ++E +R+
Sbjct: 513 YRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERR 572
Query: 162 KRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKK 202
++ + ++E + E +E ++++E++E+RE E ++E +K
Sbjct: 573 RQPQIKQEPESE---EEEEEKQEKEEKREEPMEEEEEPEQK 610
Score = 73.9 bits (180), Expect = 1e-13
Identities = 47/179 (26%), Positives = 97/179 (54%), Gaps = 5/179 (2%)
Query: 31 QRESERKKERREREKRKRERE---KERKRERGKKEKKKRKKRERGKERERKRKEREKQRK 87
+ + E ERR+ E++ RE+E +ER + +E+KK ++ E+ ERE +R+ RE ++
Sbjct: 434 EEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERR-REMAKE 492
Query: 88 ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKER 147
+R KE + + + + RG +K+ ++R E+E E +R ++ K+ ++ R++
Sbjct: 493 AKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDR-EKEMEADERDRKREKEELEEIRQRLL 551
Query: 148 KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
E +R +++ E R + + + E ++E E K+ +E K+E E ++ E+K
Sbjct: 552 AEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Score = 52.8 bits (125), Expect = 3e-07
Identities = 28/101 (27%), Positives = 55/101 (54%)
Query: 28 PCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK 87
P R S +K R+REK E++RKRE+ + E+ +++ G +R +Q
Sbjct: 510 PKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEA 569
Query: 88 ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENK 128
ERR + + K++ E ++ E +++ + E++++ +E E E K
Sbjct: 570 ERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Score = 48.5 bits (114), Expect = 6e-06
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Query: 23 SHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRER-GKERERKRKE 81
S + K RE E + + R+R++ K E E+ R+R + + +R +E ER+R+
Sbjct: 516 SALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQP 575
Query: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKK 116
+ KQ E E+E K++KE+K+ E + +K
Sbjct: 576 QIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Score = 31.2 bits (69), Expect = 1.0
Identities = 17/62 (27%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
Query: 18 QMVSCSHISKPCTQRESERKKERREREKRKREREK-ERKRERGKKEKKKRKKRERGKERE 76
++++ H + E++ ERR + + K+E E E + E+ +KE+K+ + E +E E
Sbjct: 549 RLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPE 608
Query: 77 RK 78
+K
Sbjct: 609 QK 610
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 141 bits (355), Expect = 7e-34
Identities = 81/204 (39%), Positives = 141/204 (69%), Gaps = 21/204 (10%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR-KEREKQRKER 89
QRE +R +E+ E+E R+R+++R RER +KEK+ + R+R K+ E +R +EREKQ+
Sbjct: 78 QRERDRVREKTEKE---RDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
Query: 90 REKER-------RKRKKEKKKRERKQR-GRRERKKKKERKERERENKQRRERKRKKRRKK 141
RE++R R R+KE++++ K R G+RE + ++ER +RERE ++ RE +R + R++
Sbjct: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERER-DREREKQKERETERDRDRQR 193
Query: 142 KRRKERKREKERGKRERKRKKRKKEEREKKRERNR-----KERKKERERKERRERKKERK 196
KER+R+ +R +R+R+RK + + +RE RE R +ER+++R+R + R+R+++RK
Sbjct: 194 DTEKERERQTDR-ERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRK 252
Query: 197 KERRK--KKERKKDRKTDRQTDSQ 218
+ER+K KKERKK+RK ++ + +
Sbjct: 253 EERKKERKKERKKERKEKKKEEKR 276
Score = 141 bits (355), Expect = 7e-34
Identities = 84/196 (42%), Positives = 141/196 (71%), Gaps = 20/196 (10%)
Query: 32 RESERKKERREREK---RKREREK----ERKRERGKKEKKKRKKRERGKERERKRKEREK 84
R+ +R +ERR +EK R R+REK ER RER +K+K + ++R+RG+ERER R +REK
Sbjct: 94 RDRKRDRERRRKEKETNRNRDREKQTEIERDRER-EKQKGRERERDRGRERERDR-DREK 151
Query: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERK-ERERENKQRRERKRKKRRKKKR 143
+R+ + EK+R +++ + +RER RER+K+KER+ ER+R+ ++ E++R+++ ++R
Sbjct: 152 ERERQTEKDRDGQRETETERERD----REREKQKERETERDRDRQRDTEKERERQTDRER 207
Query: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNR---KERKKERERKERR--ERKKERKKE 198
++RK + ER +RE R+ ++ +R ++R+R+R KER +ER+RKE R ERKKERKKE
Sbjct: 208 DRQRKTQTER-QRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKE 266
Query: 199 RRKKKERKKDRKTDRQ 214
R++KK+ +K R+ ++
Sbjct: 267 RKEKKKEEKRREDKKR 282
Score = 139 bits (350), Expect = 3e-33
Identities = 77/194 (39%), Positives = 132/194 (68%), Gaps = 15/194 (7%)
Query: 35 ERKKER-REREKRKREREKERKRERGKKEKKKRKKR----------ERGKERER-KRKER 82
+R++ER R REK ++ER+++RKR+R ++ K+K R ER +ERE+ K +ER
Sbjct: 76 DRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRER 135
Query: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK 142
E+ R RE++R + K+ +++ E+ + G+RE + ++ER +RERE ++ RE +R + R++
Sbjct: 136 ERDRGRERERDRDREKERERQTEKDRDGQRETETERER-DREREKQKERETERDRDRQRD 194
Query: 143 RRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKK 202
KER+R+ +R +R+R+RK + + +RE RE R E + RER+ R+R KER +ER +K
Sbjct: 195 TEKERERQTDR-ERDRQRKTQTERQRETDREGER-ETDRRRERQRDRDRGKERDRERDRK 252
Query: 203 KERKKDRKTDRQTD 216
+ERKK+RK +R+ +
Sbjct: 253 EERKKERKKERKKE 266
Score = 130 bits (327), Expect = 1e-30
Identities = 69/170 (40%), Positives = 127/170 (74%), Gaps = 10/170 (5%)
Query: 32 RESERKKER-REREKRK-REREKERKRERGKKEKKKRKKRERGKERERK-RKEREKQRKE 88
RE + + ER REREK+K RERE++R RER ++++ + K+RER E++R ++E E +R+
Sbjct: 115 REKQTEIERDREREKQKGRERERDRGRER-ERDRDREKERERQTEKDRDGQRETETERER 173
Query: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKER---KERERENKQRRERKRKKRRKKKRRK 145
RE+E++K ++ ++ R+R++ +ER+++ +R ++R+ + +++RE R+ R+ RR+
Sbjct: 174 DREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRR 233
Query: 146 ERKREKERGK---RERKRKKRKKEEREKKRERNRKERKKERERKERRERK 192
ER+R+++RGK RER RK+ +K+ER+K+R++ RKE+KKE +R+E ++RK
Sbjct: 234 ERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
Score = 117 bits (293), Expect = 1e-26
Identities = 67/193 (34%), Positives = 123/193 (63%), Gaps = 19/193 (9%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
+ES R + K +++R+R+R +++ +K + R+R ++RER+RKE+E R RE
Sbjct: 57 QESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDRE 116
Query: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151
K+ + E+ + KQ+GR ERER+ + RER R + ++++R+ E+ R+
Sbjct: 117 KQT---EIERDREREKQKGR----------ERERDRGRERERDRDREKERERQTEKDRDG 163
Query: 152 ER---GKRERKRKKRKKEEREKKRERNR-KERKKERERKERRERKKERK--KERRKKKER 205
+R +RER R++ K++ERE +R+R+R ++ +KERER+ RER ++RK ER+++ +R
Sbjct: 164 QRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDR 223
Query: 206 KKDRKTDRQTDSQ 218
+ +R+TDR+ + Q
Sbjct: 224 EGERETDRRRERQ 236
Score = 106 bits (264), Expect = 3e-23
Identities = 57/152 (37%), Positives = 104/152 (68%), Gaps = 10/152 (6%)
Query: 70 ERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ 129
+R +ER+R R++ EK+R R+++R +R+KEK+ R R K+ + ++RERE ++
Sbjct: 76 DRQRERDRVREKTEKERDRDRKRDRERRRKEKETN----RNRDREKQTEIERDREREKQK 131
Query: 130 RRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERR 189
RER+R + R+++R ++R++E+ER + E+ R +++ E E++R+R R E++KERE + R
Sbjct: 132 GRERERDRGRERERDRDREKERER-QTEKDRDGQRETETERERDRER-EKQKERETERDR 189
Query: 190 ERKKERKKERRKKKERKKDRKTDRQTDSQVFR 221
+R+++ +KER ER+ DR+ DRQ +Q R
Sbjct: 190 DRQRDTEKER----ERQTDRERDRQRKTQTER 217
Score = 95.5 bits (236), Expect = 4e-20
Identities = 55/127 (43%), Positives = 96/127 (75%), Gaps = 9/127 (7%)
Query: 31 QRESERKKER-REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRK-EREKQRKE 88
QRE+E ++ER REREK+K ERE ER R+R +++ +K ++R+ +ER+R+RK + E+QR+
Sbjct: 164 QRETETERERDREREKQK-ERETERDRDR-QRDTEKERERQTDRERDRQRKTQTERQRET 221
Query: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
RE ER ++ +++R+R RG+ ER ++++RKE E K+ R+++RKK RK+K+++E++
Sbjct: 222 DREGERETDRRRERQRDR-DRGK-ERDRERDRKE---ERKKERKKERKKERKEKKKEEKR 276
Query: 149 REKERGK 155
RE ++ K
Sbjct: 277 REDKKRK 283
Score = 65.1 bits (157), Expect = 6e-11
Identities = 37/83 (44%), Positives = 56/83 (67%), Gaps = 12/83 (14%)
Query: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
K T+R+ E +E R+RER+ R R+RGK ER +ER+RK +ER+K+R
Sbjct: 212 KTQTERQRETDREGERETDRRRERQ--RDRDRGK---------ERDRERDRK-EERKKER 259
Query: 87 KERREKERRKRKKEKKKRERKQR 109
K+ R+KER+++KKE+K+RE K+R
Sbjct: 260 KKERKKERKEKKKEEKRREDKKR 282
Score = 50.4 bits (119), Expect = 2e-06
Identities = 26/63 (41%), Positives = 39/63 (61%), Gaps = 9/63 (14%)
Query: 30 TQRESERKKERREREKRKREREKERKRERG---------KKEKKKRKKRERGKERERKRK 80
T RE ER+ +RR +R R+R KER RER KKE+KK +K ++ +E+ R+ K
Sbjct: 221 TDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDK 280
Query: 81 ERE 83
+R+
Sbjct: 281 KRK 283
Score = 42.4 bits (98), Expect = 4e-04
Identities = 21/46 (45%), Positives = 32/46 (69%), Gaps = 3/46 (6%)
Query: 32 RESERKKERREREKRKREREKERKRERG---KKEKKKRKKRERGKE 74
R ER +ER +E+RK+ER+KERK+ER K+EK++ K+ + E
Sbjct: 241 RGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
Score = 40.8 bits (94), Expect = 0.001
Identities = 15/43 (34%), Positives = 34/43 (79%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGK 73
+R+ ER ++ +++RK+ER+KERK ++ ++++++ KKR+ G+
Sbjct: 244 ERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 138 bits (348), Expect = 5e-33
Identities = 63/181 (34%), Positives = 126/181 (69%), Gaps = 2/181 (1%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
E + + + R+ +R E++R+ R + ++ R +G+ E +R ER ++R+ R
Sbjct: 610 ERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVD 669
Query: 93 ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE 152
+RR + ++ RER++ RER++++ER +RERE ++ ER+R + R+++R KER RE++
Sbjct: 670 DRRDERARERDRERERDRERERERERER-DREREKERELERERAREREREREKERDRERD 728
Query: 153 RGK-RERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKT 211
R + +R+R++ ++ +REK+RER R+ER++ERER+ RER++ER++ER ++++++++R+
Sbjct: 729 RDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQR 788
Query: 212 D 212
D
Sbjct: 789 D 789
Score = 135 bits (341), Expect = 3e-32
Identities = 68/193 (35%), Positives = 131/193 (67%), Gaps = 6/193 (3%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR---KEREKQRK 87
+R +R +RR+ R+R+RE+ER RER ++E+++ + RER KERE +R +ERE++R+
Sbjct: 662 ERRVDRVDDRRDERARERDRERERDRER-ERERERERDREREKERELERERARERERERE 720
Query: 88 ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKER 147
+ R++ER + + ++RER++ RE+++++ER+ERERE ++ RER+R++ R+++R +ER
Sbjct: 721 KERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARER 780
Query: 148 KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207
+E+ER +R+ + K + +++R +KRE R++R ER+ +K+ R + ++ K
Sbjct: 781 DKERER-QRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPK 839
Query: 208 DRKTDRQTDSQVF 220
R+ + DS +
Sbjct: 840 -RRREHSPDSDAY 851
Score = 132 bits (332), Expect = 3e-31
Identities = 70/194 (36%), Positives = 132/194 (68%), Gaps = 14/194 (7%)
Query: 31 QRESER-KKERREREKRKR----------EREKERKRERGKKEKKKRKKRERGKERERKR 79
+R ER +++ RER++R E E++ +RE + ++ ++ ER +ER+R+R
Sbjct: 624 RRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRER 683
Query: 80 KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR 139
ER+++R+ RE+ER + ++++++ ER++ RER+++KER +RER+ + +R+R++ R
Sbjct: 684 -ERDRERERERERERDREREKERELERERAREREREREKER-DRERDRDRDHDRERERER 741
Query: 140 KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER 199
++ R KER+RE+E +RER+R++ ++ ERE++RER R ER KERER+ E K + + +R
Sbjct: 742 ERDREKEREREREERERERERERERERERERERERAR-ERDKERERQRDWEDKDKGRDDR 800
Query: 200 RKKKERKKDRKTDR 213
R+K+E ++ + R
Sbjct: 801 REKREEIREDRNPR 814
Score = 129 bits (325), Expect = 2e-30
Identities = 69/184 (37%), Positives = 119/184 (64%), Gaps = 4/184 (2%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
E +R ER R++ + + R ER +++ ++R +R R + R + E +R ERRE+
Sbjct: 604 ERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRND-ELERDERREE 662
Query: 93 ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE 152
R R +++ ++R R + ++ +ERERE + RE++R+ R++ R +ER+REKE
Sbjct: 663 RRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKE 722
Query: 153 RGKRERKRKKRKKEEREKKRERNR-KERKKERERKER-RERKKERKKERRKKKERKKDRK 210
R RER R + ERE++RER+R KER++ERE +ER RER++ER++ER +++ER ++R
Sbjct: 723 RD-RERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERD 781
Query: 211 TDRQ 214
+R+
Sbjct: 782 KERE 785
Score = 126 bits (317), Expect = 2e-29
Identities = 67/196 (34%), Positives = 133/196 (67%), Gaps = 9/196 (4%)
Query: 27 KPCTQRESERKKERREREKRKREREKER---KRERGKKEKKKRKKRERGKERERKRKERE 83
+P + + + + ER++R+ ER +R +R+ +E+ + ++R+R +ERER+R ER+
Sbjct: 640 RPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERER-ERD 698
Query: 84 KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKR 143
++R++ RE ER + ++ +++RE+++ R+R + +R ERERE ++ RE++R +R +++R
Sbjct: 699 REREKERELERERAREREREREKERDRERDRDRDHDR-ERERERERDREKER-EREREER 756
Query: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER--RK 201
+ER+RE+ER +RER+R++ + ER+K+RER R K++ R +RRE+++E +++R R
Sbjct: 757 ERERERERER-ERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRD 815
Query: 202 KKERKKDRKTDRQTDS 217
+ +K +K R S
Sbjct: 816 GHDERKSKKRYRNEGS 831
Score = 115 bits (289), Expect = 3e-26
Identities = 77/254 (30%), Positives = 137/254 (53%), Gaps = 24/254 (9%)
Query: 31 QRESERKKERREREKRKREREKERKRERGK-----KEKKKRKKRERGKERERKRKEREKQ 85
+RE ER+ ER +R+REREKER RER + +E+++ ++R+R KERER+R+ERE++
Sbjct: 700 EREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERE 759
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKEREREN-KQRRERKRKKRRKKKRR 144
R+ RE+ER + ++ ++ RER + RER++ E K++ R++ +++RE R+ R +
Sbjct: 760 RERERERERERERERERARERDK--ERERQRDWEDKDKGRDDRREKREEIREDRNPRDGH 817
Query: 145 KERKREK----ERGKRERKRKKRKKEEREKKRERNRKERKKERER--------KERRERK 192
ERK +K E R+ KR++E N + K E+ R +E R
Sbjct: 818 DERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLS 877
Query: 193 KERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVFRYRIFHTGLDHFPIK 252
E R+ + +++DRK +R+ S+ + E + V+ V + R L+ ++
Sbjct: 878 PSHLTEDRQGRWKEEDRKPERKESSRRY----EEQELKEKVSSVDKQREQTEILESSRMR 933
Query: 253 TNILLSRHEVNDGE 266
++ H+ D E
Sbjct: 934 AQDIIGHHQSEDRE 947
Score = 108 bits (270), Expect = 5e-24
Identities = 63/188 (33%), Positives = 116/188 (61%), Gaps = 5/188 (2%)
Query: 44 EKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKK 103
E R E++R ER +++ + ER +R RE+ ++ + R E ++
Sbjct: 597 ETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELER 656
Query: 104 RERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKR 163
ER++ R +R + R ER RE + RER R++ R+++R ++R+REKER + ER+R +
Sbjct: 657 DERREERRVDRVDDR-RDERARERDRERERDRERERERERERDREREKER-ELERERARE 714
Query: 164 KKEEREKKRERNRKERKKERERKERRERKKERKKER-RKKKERKKDRKTDRQTDSQVFRP 222
++ EREK+R+R R +R ++ +R+ RER+++R+KER R+++ER+++R+ +R+ + + R
Sbjct: 715 REREREKERDRER-DRDRDHDRERERERERDREKEREREREERERERERERERERERERE 773
Query: 223 LRESAFNR 230
RE A R
Sbjct: 774 -RERARER 780
Score = 89.7 bits (221), Expect = 2e-18
Identities = 60/200 (30%), Positives = 98/200 (49%), Gaps = 20/200 (10%)
Query: 32 RESERKKERREREKRKRER-----EKERKRERGKKEKKKRKKRE-------RGKERERKR 79
R R + R +R R R R EK + RG + R ER R
Sbjct: 548 RNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDR 607
Query: 80 KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR 139
R + R+ +R E+ +R+ ++R +R + + + + R +R+ R
Sbjct: 608 YPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDR 667
Query: 140 KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNR-KERKKERERKERRERKKERKKE 198
RR ER RE++R +RER R ERE++RER R +ER+KERE + R R++ER++E
Sbjct: 668 VDDRRDERARERDR-ERERDR------ERERERERERDREREKERELERERARERERERE 720
Query: 199 RRKKKERKKDRKTDRQTDSQ 218
+ + +ER +DR DR+ + +
Sbjct: 721 KERDRERDRDRDHDRERERE 740
Score = 83.6 bits (205), Expect = 2e-16
Identities = 57/193 (29%), Positives = 94/193 (48%), Gaps = 8/193 (4%)
Query: 31 QRESERKKERRE--REKRKREREKERKRERGK----KEKKKRKKRERGKERERKRKEREK 84
+ ES R + R E E R R R RG+ EK R R +
Sbjct: 535 REESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHD 594
Query: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK-RKKRRKKKR 143
+ R R R E+ R++ + ER+ + + RE QR R + R +
Sbjct: 595 SWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDEL 654
Query: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
++ +RE+ R R R+ + ER+++RER+R ER++ERER+ RER+KER+ ER + +
Sbjct: 655 ERDERREERRVDRVDDRRDERARERDRERERDR-ERERERERERDREREKERELERERAR 713
Query: 204 ERKKDRKTDRQTD 216
ER+++R+ +R +
Sbjct: 714 EREREREKERDRE 726
Score = 72.8 bits (177), Expect = 3e-13
Identities = 49/221 (22%), Positives = 96/221 (43%), Gaps = 18/221 (8%)
Query: 28 PCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK 87
P R + + R+RE R R+++ E + + + E + R E + +
Sbjct: 495 PRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSE 554
Query: 88 ERREKERRKRKKEKKKRERKQRGRR-----------------ERKKKKERKERERENKQR 130
R ++ R R + + E+ RG R E + ++R E R
Sbjct: 555 IRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNR 614
Query: 131 RERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRE 190
+ + ++ ++R+ +ER +R + + E +R+ R+ER+ +R R E
Sbjct: 615 DQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDE 674
Query: 191 RKKERKKERRKKKERKKDRKTDRQTDSQVFRPL-RESAFNR 230
R +ER +ER + +ER+++R+ +R + + R L RE A R
Sbjct: 675 RARERDRERERDRERERERERERDREREKERELERERARER 715
Score = 68.9 bits (167), Expect = 4e-12
Identities = 52/219 (23%), Positives = 98/219 (44%), Gaps = 16/219 (7%)
Query: 15 TELQMVSCSHIS-------KPCTQRESE----RKKERREREKRKREREKERKRERGKKEK 63
T ++ V H++ KP Q+ S + R R R + G +
Sbjct: 1163 TRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQS 1222
Query: 64 KKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKER 123
+++ G K K E + + ++ KR + + ++ R ++ E
Sbjct: 1223 GRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPES 1282
Query: 124 ERENKQRRERKRKKRRKKKR-RKERKREKERGKRE-RKRKKRKKEEREKKRERNR---KE 178
+R+ R + R ++R R E RE+ER +R+ R+R+ + +++ R R+R +E
Sbjct: 1283 DRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRE 1342
Query: 179 RKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDS 217
R++ERER +RR+ +ER++ ER +DR DR +S
Sbjct: 1343 RERERERDKRRDLDRERERLISDSVERDRDRDRDRTFES 1381
Score = 68.6 bits (166), Expect = 6e-12
Identities = 46/177 (25%), Positives = 83/177 (46%), Gaps = 8/177 (4%)
Query: 39 ERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRK 98
ER+ R + + E R +++ + R E +R+ R R + R R
Sbjct: 1246 ERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRY 1305
Query: 99 KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERG-KRE 157
+ ++RER++R R+R E +R+ + R R + R ++R +ER+R+K R RE
Sbjct: 1306 EHDRERERERRDTRQR-------EWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRE 1358
Query: 158 RKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQ 214
R+R ER++ R+R+R + E +R E K E + ER + + D++
Sbjct: 1359 RERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKE 1415
Score = 65.5 bits (158), Expect = 5e-11
Identities = 52/246 (21%), Positives = 96/246 (39%), Gaps = 46/246 (18%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
T + +R+ ERRE + KR+REK+ + ER ++ + + R R ++R R R
Sbjct: 406 TSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTR 465
Query: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERE-RENKQRRERK-RKKRRKKKRRKER 147
+E R + + RE + R ++ + R R R+ R+R+ R RK+ E
Sbjct: 466 DRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEE 525
Query: 148 KREKERG--KRERKRKKRKKEEREKKRERNRKERK------------------------- 180
R R + E R + + E R + R R +R
Sbjct: 526 SRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDS 585
Query: 181 -----------------KERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPL 223
ER+R R+ + + + +++ ++DR+ +R+ D + P+
Sbjct: 586 HSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPI 645
Query: 224 RESAFN 229
R N
Sbjct: 646 RHQGRN 651
Score = 64.7 bits (156), Expect = 8e-11
Identities = 40/179 (22%), Positives = 80/179 (44%), Gaps = 10/179 (5%)
Query: 39 ERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRK 98
+R++ R R +E+ R ++ + +R +E R +++REK +E RE E+ +
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSS 442
Query: 99 KEKKKRERKQRGRRERKKKKERKERE--------RENKQRRERKRKKRRKKKRRKERKRE 150
+ +R+ R R+R+ ++ ++R R++++ R+ R + + R R
Sbjct: 443 SRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTR 502
Query: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDR 209
R+R+ + ++E E R RE R E + E + E R E + DR
Sbjct: 503 DAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESR--SEIRNDR 559
Score = 63.5 bits (153), Expect = 2e-10
Identities = 48/200 (24%), Positives = 84/200 (42%), Gaps = 9/200 (4%)
Query: 24 HISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKERE 83
H P +R +R +R ++K+ R R RE+ R + E
Sbjct: 345 HSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHE 404
Query: 84 K------QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKK 137
+ +R ERRE R KR +EK RE ++ + + + R +RE + + R R
Sbjct: 405 RTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDT 464
Query: 138 RRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER-RERKKERK 196
R +++ R R R R+ R KE R+ + R+ ++ R+R+ R RK++
Sbjct: 465 RDRRELRDSRDMRDSREMRDYSRD--TKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTY 522
Query: 197 KERRKKKERKKDRKTDRQTD 216
E + R R+ +T+
Sbjct: 523 PEESRSYGRNHLREESSRTE 542
Score = 62.8 bits (151), Expect = 3e-10
Identities = 55/273 (20%), Positives = 112/273 (41%), Gaps = 56/273 (20%)
Query: 8 RAAVKLNTELQMVSCSHISKPCTQRESERKKERR---------EREKRKREREKERKRER 58
R+ + + L+ S S K + S KK+R+ ++++ + + ++K R
Sbjct: 203 RSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPR 262
Query: 59 --------------GKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKR 104
GKK K+K K ++R +E+ R K+R + + +REK + R +
Sbjct: 263 TPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQ 322
Query: 105 ERKQRGRRERKKKKERKERERENKQRRERKR---------------------------KK 137
R + + + RKR
Sbjct: 323 HHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSP 382
Query: 138 RRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKK 197
+RK+ + R +E+G+ + +R + + R ++RE R +R +E++ +E RE ++++
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSS 442
Query: 198 ERRKKKERK----KDRKTDRQTDSQVFRPLRES 226
R + +R+ +DR+ R T + R LR+S
Sbjct: 443 SRDHRDDREPRDGRDRRDARDTRDR--RELRDS 473
Score = 62.4 bits (150), Expect = 4e-10
Identities = 52/252 (20%), Positives = 105/252 (41%), Gaps = 17/252 (6%)
Query: 28 PCTQRESERKKERREREKRKREREKERKRE---RGKKEKKKRKKRERGKERERKR-KERE 83
P R R+K R + E+ + ++ +R RGK++++K + ER E+++ ++
Sbjct: 388 PPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHR 447
Query: 84 KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK--RKKRRKK 141
R+ R ++RR + + +RE R R+ + +E ++ R+ K+ R+ + R R
Sbjct: 448 DDREPRDGRDRRDARDTRDRRE--LRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAH 505
Query: 142 KRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
R R+ R + + R + E +R E + E + R E + +R R
Sbjct: 506 DYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRG 565
Query: 202 KKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVFRYRIFHTGLDHFPIKTNILLSRHE 261
+ ++ + SQ+ +S + + R + D +P + N R +
Sbjct: 566 RVPELPEKGSRGSRGSQI-----DSHSSNSNYHDSWETRSSYPERDRYPERDN----RDQ 616
Query: 262 VNDGEIEVNDGE 273
D E GE
Sbjct: 617 ARDSSFERRHGE 628
Score = 62.0 bits (149), Expect = 5e-10
Identities = 56/264 (21%), Positives = 107/264 (40%), Gaps = 76/264 (28%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKK-----RKKRERGKERERKRK---ER 82
+RE ER++ER +R RER+KER+R+R ++K K R+KRE +E R ER
Sbjct: 761 ERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDER 820
Query: 83 EKQRKERREKERRKRKKEKKKRERKQ---------------------------------- 108
+ +++ R E R+ K++RE
Sbjct: 821 KSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSH 880
Query: 109 --RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR----------------- 149
R+ R K+++RK +E+ +R E + K + K+R++
Sbjct: 881 LTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGH 940
Query: 150 ---------------EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
K++ K ++K K+KKE+ N + ++ + ++ +K+
Sbjct: 941 HQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKK 1000
Query: 195 RKKERRKKKERKKDRKTDRQTDSQ 218
+ E+++KK + +D + Q
Sbjct: 1001 KSIEKKRKKSKGDSDISDEEAAQQ 1024
Score = 61.2 bits (147), Expect = 9e-10
Identities = 40/181 (22%), Positives = 77/181 (42%), Gaps = 2/181 (1%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Q + RE+ + ER + R ++ + R KR+R K+ +R+ + Q R
Sbjct: 386 QSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRD 445
Query: 91 EKERRKRKKEKKKRE-RKQRGRRE-RKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
++ R+ + + +R+ R R RRE R + R RE + R ++ + R + ++
Sbjct: 446 HRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAH 505
Query: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
++R R+ RK+ E + RN + R R + R + R + R +
Sbjct: 506 DYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRG 565
Query: 209 R 209
R
Sbjct: 566 R 566
Score = 61.2 bits (147), Expect = 9e-10
Identities = 50/234 (21%), Positives = 96/234 (41%), Gaps = 21/234 (8%)
Query: 4 AISSRAAVKLNTELQMVSCSHISKPCTQR----ESERKKERREREKRKREREKERKRERG 59
A ++ AA +T +S S T E +K R R ++ + +
Sbjct: 1121 ATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQH 1180
Query: 60 KKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKK- 118
+K +++ G R + + R + R + ++ G R+R+K K
Sbjct: 1181 RKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKS 1240
Query: 119 -----ERKERERENKQRR-ERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKR 172
ERK R + K+ R R+ R +R R+ + + R++ +
Sbjct: 1241 LEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQ 1300
Query: 173 ERNRKERKKERERKERRERKKE----------RKKERRKKKERKKDRKTDRQTD 216
ER+R E +ERER+ R R++E R ++R + +ER+++R+ D++ D
Sbjct: 1301 ERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRD 1354
Score = 60.1 bits (144), Expect = 2e-09
Identities = 46/218 (21%), Positives = 96/218 (44%), Gaps = 55/218 (25%)
Query: 49 EREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR---------------------- 86
++ KE+ + + + E+K R ++RG++ ER+R++R+K R
Sbjct: 278 KKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQ 337
Query: 87 -----KERREKERRKRKKEKKKR----------------------ERKQRGRRERKKKKE 119
+ RRKR + +RKQ R R +E
Sbjct: 338 SGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMRE 397
Query: 120 R----KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERN 175
+ ER ++ RR +R+ R K+ R++ RE+ ++++ + +++RE + R+
Sbjct: 398 KGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRD 457
Query: 176 RKERKKERERKERRERKKERKKERRKKKERKKDRKTDR 213
R++ + R+R+E R+ + R + R+ ++ +D K R
Sbjct: 458 RRDARDTRDRRELRDSRDMR--DSREMRDYSRDTKESR 493
Score = 57.0 bits (136), Expect = 2e-08
Identities = 42/190 (22%), Positives = 83/190 (43%), Gaps = 11/190 (5%)
Query: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
+P S+R+ R +R + R + + +ER + + +ERE++
Sbjct: 1258 EPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRD 1317
Query: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
+RE +R K + R+R + RER+++++++ R+ + RER ++ R ++
Sbjct: 1318 TRQREWDRDADKDWPRNRDRDRLRERERERERDKR---RDLDRERERLISDSVERDRDRD 1374
Query: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRER--------KKERKKE 198
R R E + E ++ K E E +R+ R KER ++ ++ K E
Sbjct: 1375 RDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSE 1434
Query: 199 RRKKKERKKD 208
R + E D
Sbjct: 1435 RTESLEAGDD 1444
Score = 54.3 bits (129), Expect = 1e-07
Identities = 44/183 (24%), Positives = 87/183 (47%), Gaps = 16/183 (8%)
Query: 26 SKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERER-------- 77
S+ + R S + +R+ + ++R +ER + E + ++RER R+R
Sbjct: 1270 SRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADK 1329
Query: 78 ---KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK 134
+ ++R++ R+ RE+ER KR+ ++RER ER + ++R +R E+ Q +
Sbjct: 1330 DWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDR-DRTFESSQ---IE 1385
Query: 135 RKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
KR + K E +R+ E R+ +++ +++ + +E K ER E E +
Sbjct: 1386 SVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKS-ERTESLEAGDD 1444
Query: 195 RKK 197
K
Sbjct: 1445 ESK 1447
Score = 51.2 bits (121), Expect = 1e-06
Identities = 45/193 (23%), Positives = 89/193 (46%), Gaps = 7/193 (3%)
Query: 16 ELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKER 75
E + +S SH+++ R E ++ +E +R E+E K + +K++ + R
Sbjct: 872 ESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSR 931
Query: 76 ERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135
R + + E RE R + KKK K + + +KKK++ ER N +
Sbjct: 932 MRAQDIIGHHQSEDRETSDRAHDENKKK--AKIQKKPIKKKKEDDVGIERGNIETTSEDG 989
Query: 136 K----KRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRER 191
+ K+ +KK+ E+KR+K +G + ++ ++ ++K+ R KE E E
Sbjct: 990 QVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKE-ELVEMCNG 1048
Query: 192 KKERKKERRKKKE 204
K ++ +KK++
Sbjct: 1049 KNGILEDSQKKED 1061
Score = 49.3 bits (116), Expect = 4e-06
Identities = 46/222 (20%), Positives = 90/222 (40%), Gaps = 23/222 (10%)
Query: 13 LNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKK---- 68
++TE Q + S P + S + +E K +ER E + E + E +
Sbjct: 96 VDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGD 155
Query: 69 ------RERGKERERKRKEREKQRKERREKERRKR---KKEKKKRERKQRGRRERKKKKE 119
E E +R++ +RE + E+ E+R+ KKE + + +K
Sbjct: 156 INYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKS 215
Query: 120 RKERERENKQRRERKRKKRRK----------KKRRKERKREKERGKRERKRKKRKKEERE 169
K +R++ + KK RK ++R + + K++G R E+
Sbjct: 216 SKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIA 275
Query: 170 KKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKT 211
++ K + K+R ++ R+ K + R++++R K R T
Sbjct: 276 LGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRST 317
Score = 49.3 bits (116), Expect = 4e-06
Identities = 45/215 (20%), Positives = 95/215 (44%), Gaps = 15/215 (6%)
Query: 21 SCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR- 79
S SH S+ + ES+R+ R R+R +ER R +E RER + R+R
Sbjct: 1270 SRSHSSRRSSP-ESDRQVHSRSGSFDSRDRLQERDRYEHDRE------RERERRDTRQRE 1322
Query: 80 --KEREKQRKERREKER-RKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK 136
++ +K R+++R R+R++E+++ +R+ R + + ER+R+ R+R R
Sbjct: 1323 WDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRD----RDRDRT 1378
Query: 137 KRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERK 196
+ +R K G+ ER + ++ +ER K+ + +E + ++
Sbjct: 1379 FESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTES 1438
Query: 197 KERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRV 231
E + + D + + + P+ + + +
Sbjct: 1439 LEAGDDESKLDDAHSLGSGAGEGYEPISDDELDEI 1473
Score = 48.5 bits (114), Expect = 6e-06
Identities = 44/188 (23%), Positives = 78/188 (41%), Gaps = 12/188 (6%)
Query: 31 QRESERKK-ERREREKRKREREKERKRERGKKEKKK--RKKRERGKERERKRKEREKQRK 87
+R ER + RER K KR+ ++R +E RK+ RG+ RE KE K K
Sbjct: 75 RRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHRE---KEDIKITK 131
Query: 88 ERREKERRKRKKEKKKRERKQRGR------RERKKKKERKERERENKQRRERKRKKRRKK 141
ER + + + + R+ G E + +R++ +RE + + +KR +
Sbjct: 132 ERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEI 191
Query: 142 KRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
+KE E R K RK + K++ + +++RK ++R
Sbjct: 192 IIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNS 251
Query: 202 KKERKKDR 209
K + K +
Sbjct: 252 KTNQSKKK 259
Score = 47.8 bits (112), Expect = 1e-05
Identities = 36/173 (20%), Positives = 82/173 (47%), Gaps = 10/173 (5%)
Query: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKER 94
++ ++ R + R +E E ++ + +E ++ ERK R + +E +EK
Sbjct: 856 DKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVS 915
Query: 95 R--KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK- 151
K++++ + E + ++ + ++RE ++ E K+K + +KK K++K +
Sbjct: 916 SVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDV 975
Query: 152 --ERGKRERKRK-----KRKKEEREKKRERNRKERKKERERKERRERKKERKK 197
ERG E + KK +++K E+ RK+ K + + + ++ +KK
Sbjct: 976 GIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKK 1028
Score = 42.7 bits (99), Expect = 3e-04
Identities = 48/239 (20%), Positives = 94/239 (39%), Gaps = 48/239 (20%)
Query: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRER-----GKERERKRKE 81
+P K +R++ + ++R E +KE + + RE+ KER + +E
Sbjct: 80 RPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESEE 139
Query: 82 REKQRKERR------------------EKERRKRKKEKKKRERKQRGRRER-KKKKERKE 122
+ + R E +R+K ++E K E++ +RE KKE
Sbjct: 140 ENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSP 199
Query: 123 RERENKQRRERKRKKRRKKKRRKERKREKERGKRERK-----------RKKRKKEEREKK 171
+K +K K +RK + K++RK ++ K + +KK
Sbjct: 200 EVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKK 259
Query: 172 RERN-------------RKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDS 217
R K+ K++ + K+R E K K+R + ER+++++ ++ S
Sbjct: 260 GPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTS 318
Score = 41.6 bits (96), Expect = 8e-04
Identities = 48/208 (23%), Positives = 82/208 (39%), Gaps = 29/208 (13%)
Query: 21 SCSHISKPCTQRESERKKERREREKRK---REREKERKRERGKKEKKKRKKRE------- 70
+C + P + + RR E+ RER K KR+ E +KR E
Sbjct: 56 TCRFVHGPSPRGKGYSSNYRRSPERPTGDLRERMKN-KRQDVDTEPQKRNTEESSSPVRK 114
Query: 71 ---RGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGR------RERKKKKERK 121
RG+ RE KE K KER + + + + R+ G E + +R+
Sbjct: 115 ESSRGRHRE---KEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQ 171
Query: 122 ERERENKQRRERKRKKRRKKKRRKERKREKERGK------RERKRKKRKKEEREKKRERN 175
+ +RE + + +KR + +KE E R K + K K++ K +
Sbjct: 172 KIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSAS 231
Query: 176 RKERKKERERKERRERKKERKKERRKKK 203
+K+RK ++++ K + KKK
Sbjct: 232 KKDRKTSAVSSPLLDQQRNSKTNQSKKK 259
Score = 39.3 bits (90), Expect = 0.004
Identities = 46/202 (22%), Positives = 79/202 (39%), Gaps = 15/202 (7%)
Query: 34 SERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93
S R K +R ER RER K + + + E +++ E+ R++
Sbjct: 64 SPRGKGYSSNYRRSPERPTGDLRER-------MKNKRQDVDTEPQKRNTEESSSPVRKES 116
Query: 94 RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE-RKRKKRRKKKRRKERKREKE 152
R R +EK+ + + E +++ E R++ + K +K ++E
Sbjct: 117 SRGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRE 176
Query: 153 RGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKK--ERKKERRKKKERKKDRK 210
K E++ ++++E KK R K R+ K +RK + KKDRK
Sbjct: 177 LMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRK 236
Query: 211 TDRQTDSQVFRPLRESAFNRVT 232
T S V PL + N T
Sbjct: 237 T-----SAVSSPLLDQQRNSKT 253
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 134 bits (336), Expect = 1e-31
Identities = 67/204 (32%), Positives = 131/204 (64%), Gaps = 6/204 (2%)
Query: 14 NTELQMVSCSHISKPCTQRESERKKERREREK---RKREREKERKRERGK-KEKKKRKKR 69
+TE + + + T RE +R KE + ++ R R+R++ER RER + +E++K+ R
Sbjct: 11 HTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDR 70
Query: 70 ERGKERERKR-KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENK 128
E ++RER+R ++R+++ + R+KER + + RER+++ RE ++ ++R ERE++ +
Sbjct: 71 EGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR-EREKQKE 129
Query: 129 QRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER 188
RER+ + ++R ++ +RE+E G+ + + ++ ERE+KRER RK KERER
Sbjct: 130 MGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTD 189
Query: 189 RERKKERKKERRKKKERKKDRKTD 212
ER+++R+ +R++ ++R+ +R+ D
Sbjct: 190 MERERQRETDRKRDRQRESERERD 213
Score = 131 bits (330), Expect = 6e-31
Identities = 70/195 (35%), Positives = 130/195 (66%), Gaps = 14/195 (7%)
Query: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRK-----EREKQRKER 89
+R++ERR R+R+R KE K E E+ +++ RER +ER+R R+ +RE +R+
Sbjct: 18 DRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRE 77
Query: 90 REKERRKRKKEKKKRERKQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKRRKERK 148
RE++R ++++ +++R++++ R + +ER K++ERE ++ R+R+R+K+++ R ++
Sbjct: 78 RERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTD 137
Query: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERR-----KKK 203
RE +R +RER+ ++ ++ RE+K E +ER ERERK RERK+E K+ R +++
Sbjct: 138 RETDR-ERERQAERERETGRERKTEDRHRER--ERERKRERERKRETKERERHTDMERER 194
Query: 204 ERKKDRKTDRQTDSQ 218
+R+ DRK DRQ +S+
Sbjct: 195 QRETDRKRDRQRESE 209
Score = 129 bits (325), Expect = 2e-30
Identities = 65/198 (32%), Positives = 134/198 (67%), Gaps = 11/198 (5%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
T E+E +RER +R+ +RE++R +E +++ + R+R +ER R+R +R+++R+++
Sbjct: 10 THTETETMDRQRER-RRETDRERDRAKESKTEDRHSERDRQRDRERNRER-DRDREREKQ 67
Query: 90 REKERRKRKKEKKKRERKQRGRRERKKKKE-----RKERERENKQRRERKRKKRRKKKRR 144
++E ++++ ++ R+R++ RER K++E +RER+ ++ RE +R + R+++++
Sbjct: 68 TDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQ 127
Query: 145 KERKREKERGKR-ERKRKKRKKEEREKKRERNRKERKKERERKERRERKKER---KKERR 200
KE RE++ + +R+R+++ + ERE RER ++R +ERER+ +RER+++R ++ER
Sbjct: 128 KEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERH 187
Query: 201 KKKERKKDRKTDRQTDSQ 218
ER++ R+TDR+ D Q
Sbjct: 188 TDMERERQRETDRKRDRQ 205
Score = 108 bits (271), Expect = 4e-24
Identities = 63/196 (32%), Positives = 120/196 (61%), Gaps = 15/196 (7%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
+ ++E + E E R+RE+ R+ +R + K+ K +R ER+R+R +RE+ R+ R
Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQR-DRERNRERDR 60
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKRRKERKR 149
++ER K+ + +R+R++ R+R+++ ER +++ERE + E R+++++K+R ER R
Sbjct: 61 DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVR 120
Query: 150 EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDR 209
++ER K++ ++R+ + RE RER ER+ ERER+ RERK E +R ++R
Sbjct: 121 DREREKQKEMGRERQTD-RETDRER---ERQAERERETGRERKTE---------DRHRER 167
Query: 210 KTDRQTDSQVFRPLRE 225
+ +R+ + + R +E
Sbjct: 168 ERERKRERERKRETKE 183
Score = 100 bits (249), Expect = 1e-21
Identities = 59/167 (35%), Positives = 107/167 (64%), Gaps = 9/167 (5%)
Query: 67 KKRERGKERERKRKEREKQRKERREKER-RKRKKEKKKRERKQRGRRERKKKKERKERER 125
+ + G+ + + ++QR+ RRE +R R R KE K +R ER ++++R ER R
Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDR----HSERDRQRDR-ERNR 56
Query: 126 ENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERER 185
E + RER+++ R+ +R++ER+R+++R +RE +R++ K+ E ++ E +R ER+K++ER
Sbjct: 57 ERDRDREREKQTDREGERQRERERDRDR-QRETERERDKERETDRHTETDR-ERQKQKER 114
Query: 186 KERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVT 232
+ R R +ER+K++ +ER+ DR+TDR+ + Q R RE+ R T
Sbjct: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERE-RETGRERKT 160
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 127 bits (320), Expect = 8e-30
Identities = 67/189 (35%), Positives = 128/189 (67%), Gaps = 19/189 (10%)
Query: 28 PCTQRESERKKERREREKRKREREKERKRERGK---KEKKKRKKRERGKERERKR----- 79
P RE ER++ER + KR +ER +E+ RE K +++K+ ++R+R ++R+RKR
Sbjct: 54 PAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGD 113
Query: 80 --KEREKQRKERREKER-RKRKKEKKKRERKQRG-------RRERKKKKERKERERENKQ 129
+E E +R+E RE++R RKR+K+++++ +++ G E+ + +ER+ E E +
Sbjct: 114 RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173
Query: 130 RRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNR-KERKKERERKER 188
RER+R+K+R+ +R ++R+R++E+ RER R ++K+ E+++ RER ++R KER+R+ +
Sbjct: 174 DRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQ 233
Query: 189 RERKKERKK 197
RE+ ++R+K
Sbjct: 234 REKDRDRQK 242
Score = 127 bits (320), Expect = 8e-30
Identities = 69/183 (37%), Positives = 126/183 (68%), Gaps = 12/183 (6%)
Query: 41 REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKE 100
RERE R+RERE++RKR KE+ + K RE K+R+R+RK R+++R+ R+++R++ +
Sbjct: 58 RERE-RQRERERQRKRA---KERHREKDREIEKDRDRQRK-RDRERQRWRDRDRKRERWG 112
Query: 101 KKKRERKQRGRRERKKKKERK-ERERENKQRRERKRKKRRKKKRRKERKREKERGK---- 155
+ RE + + ER+++++RK E++RE +++RE K R+ + K+R RE+E G+
Sbjct: 113 DRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERY 172
Query: 156 --RERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDR 213
RER+R+K+++ R++ RER R++ +ER+R ++ER+K+R +ER ++R K+R +R
Sbjct: 173 RDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRER 232
Query: 214 QTD 216
Q +
Sbjct: 233 QRE 235
Score = 89.7 bits (221), Expect = 2e-18
Identities = 66/190 (34%), Positives = 106/190 (55%), Gaps = 39/190 (20%)
Query: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE 132
+ERER+R ERE+QRK +E+ R K ++ +K R+R+++ ++RER+ + R+
Sbjct: 58 RERERQR-ERERQRKRAKERHREKDREIEKDRDRQRK-----------RDRERQRWRDRD 105
Query: 133 RKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNR---------------K 177
RKR++ + R E +R++ER +R+R RK REK RER R K
Sbjct: 106 RKRERWGDRDRETETERQEER-ERQRDRK------REKDRERQRQREIGIDKDREIETEK 158
Query: 178 ERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVF 237
+R +ERE E ER ++R++ER+K++E ++DR +RQ + + RE +R
Sbjct: 159 DRDREREMGE-TERYRDRERERQKQRETRRDRDRERQREKED----RERDRDRQKEREKD 213
Query: 238 RYRIFHTGLD 247
RYR TG D
Sbjct: 214 RYRERETGRD 223
Score = 84.0 bits (206), Expect = 1e-16
Identities = 51/138 (36%), Positives = 92/138 (66%), Gaps = 13/138 (9%)
Query: 31 QRESERKKERREREKRKREREKERKRERG---------KKEKKKRKKRERGK-ERERKR- 79
+ E+ER++ER + RKRE+++ER+R+R + EK + ++RE G+ ER R R
Sbjct: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
Query: 80 KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR 139
+ER+KQR+ RR+++R +R++EK+ RER + ++ER+K + R ERE + +ER R+++R
Sbjct: 177 RERQKQRETRRDRDR-ERQREKEDRERDRDRQKEREKDRYR-ERETGRDRDKERDRERQR 234
Query: 140 KKKRRKERKREKERGKRE 157
+K R +++ + G+ E
Sbjct: 235 EKDRDRQKAIDCVPGRWE 252
Score = 77.4 bits (189), Expect = 1e-14
Identities = 44/126 (34%), Positives = 82/126 (65%), Gaps = 12/126 (9%)
Query: 109 RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGK-RERKRKKRKKEE 167
RG R +ER+RE RER+RK+ +++ R K+R+ EK+R + R+R R++++ +
Sbjct: 48 RGSRVAPAIIRERERQRE----RERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRD 103
Query: 168 REKKRER-NRKERKKERERKERRERKKERKKERRKKKERK------KDRKTDRQTDSQVF 220
R++KRER ++R+ E ER+E RER+++RK+E+ ++++R+ KDR+ + + D
Sbjct: 104 RDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRE 163
Query: 221 RPLRES 226
R + E+
Sbjct: 164 REMGET 169
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 127 bits (318), Expect = 1e-29
Identities = 77/237 (32%), Positives = 130/237 (54%), Gaps = 21/237 (8%)
Query: 7 SRAAVKLNTELQMVSCSHISKPCTQRESERKKERRER---EKRKREREKERKRERGKKEK 63
SR++ K ++ + H S+ + S +K RR + +KR + RE+ + R R
Sbjct: 316 SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRD 375
Query: 64 KKRKKRERGKERER-KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE 122
K++ RE+ KE+ER K K+REK+R+ +E+E+ K + + K R++++ RE+ K+K+R E
Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDR-E 434
Query: 123 RERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERN--RKERK 180
RERE + E+ R K ++K++ KE++REK+R K +++K+ K+ R R N R+ R
Sbjct: 435 RERE--KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRS 492
Query: 181 KERERKERRERKKERKKERRK------------KKERKKDRKTDRQTDSQVFRPLRE 225
RER+ RR R R K + KKD+K +++ D R RE
Sbjct: 493 SSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERE 549
Score = 126 bits (317), Expect = 2e-29
Identities = 67/202 (33%), Positives = 118/202 (58%), Gaps = 8/202 (3%)
Query: 32 RESERKKERREREKRKREREKERKRERGK---KEKKKRKKRERGKERERKRKEREKQRKE 88
+E ER KE+ ++R+RE+E+E+++ERGK ++K++ K RE+ KE++R+R EREK+ ++
Sbjct: 385 KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER-EREKEHEK 443
Query: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
R+KE+ K + ++K+RE+ + + K+KK++K R R R + ++RR+ R
Sbjct: 444 DRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR-RSRSSSRERRRRRS 502
Query: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
R R R K KRK R RN+K++K+E+ER ER++ + +K +D
Sbjct: 503 RSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRD 562
Query: 209 RKTDRQTDSQVFRPLRESAFNR 230
K + +S L+E N+
Sbjct: 563 GKEKLEKNS---TSLKEKEHNK 581
Score = 122 bits (307), Expect = 3e-28
Identities = 67/181 (37%), Positives = 111/181 (61%), Gaps = 11/181 (6%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
ES + ER K R R R + R + R+KR + K R R ++K+RR
Sbjct: 296 ESGKSNER----KGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRS 351
Query: 93 ERRKRKKEKKKRERKQRGR-RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151
+ +K+ K + RK R R R K+K+ +E+ +E ++ +E+ R+K R+ R KER++EK
Sbjct: 352 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERE--REKEREKEK 409
Query: 152 ERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKT 211
ERGK + + K+R+K +REK +E K+R++ERE++ ++R KE++KE+ K+KER+KDR
Sbjct: 410 ERGKNKDRDKEREK-DREKDKE---KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 465
Query: 212 D 212
+
Sbjct: 466 E 466
Score = 121 bits (303), Expect = 8e-28
Identities = 64/188 (34%), Positives = 120/188 (63%), Gaps = 7/188 (3%)
Query: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR-KEREKQ 85
+P + + +ERK R R + R + R K+ + K + R + R R++ + R K
Sbjct: 294 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKS 353
Query: 86 RKERREKERRKRKKEKKKRER-KQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKR 143
++R K R +RK + R K++ RE+ K+KER KE++RE ++ RE++R+K +++ +
Sbjct: 354 PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 413
Query: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
K+R +E+E+ RE+ ++K ++ EREK+ E++R +++KE+E+ + +ER+K+R KE +K
Sbjct: 414 NKDRDKEREKD-REKDKEKDREREREKEHEKDR-DKEKEKEQDKEKEREKDRSKEIDEK- 470
Query: 204 ERKKDRKT 211
RKKD+K+
Sbjct: 471 -RKKDKKS 477
Score = 112 bits (280), Expect = 4e-25
Identities = 65/203 (32%), Positives = 112/203 (55%), Gaps = 11/203 (5%)
Query: 25 ISKPCTQRESERKKERREREKRKREREK----ERKRERGKKEKKKRKKRERGKERERKRK 80
I KP KE E KR RE + + E GK ++K + + +
Sbjct: 260 IVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSS 319
Query: 81 EREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR-- 138
+ R++R + + R R + + +K R R + KK K RER + R R KR
Sbjct: 320 SKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD 379
Query: 139 -RKKKRRKERKREKERGK-RERKRKKRKKEEREKKRERNR---KERKKERERKERRERKK 193
R+K + KER +EK+R K RER++++ K++ER K ++R++ K+R+K++E+ RER+K
Sbjct: 380 TREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREK 439
Query: 194 ERKKERRKKKERKKDRKTDRQTD 216
E +K+R K+KE+++D++ +R+ D
Sbjct: 440 EHEKDRDKEKEKEQDKEKEREKD 462
Score = 111 bits (278), Expect = 6e-25
Identities = 58/193 (30%), Positives = 116/193 (60%), Gaps = 4/193 (2%)
Query: 34 SERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93
S+ + + +RKR + K R R + +++ +R +++ K RE+++ R
Sbjct: 314 SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS 373
Query: 94 RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153
R KRK ++K + K+R + E+ ++KER ERE+E ++ +ER + K R K+R K+R+++KE+
Sbjct: 374 RDKRKDTREKIKEKERVK-EKDREKER-EREKEREKEKERGKNKDRDKEREKDREKDKEK 431
Query: 154 GKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDR 213
RER+R+K +++R+K++E+ ++++KERE+ +E ++RKK+++ + + + R
Sbjct: 432 -DREREREKEHEKDRDKEKEK-EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRR 489
Query: 214 QTDSQVFRPLRES 226
S R R S
Sbjct: 490 SRSSSRERRRRRS 502
Score = 104 bits (260), Expect = 7e-23
Identities = 61/200 (30%), Positives = 113/200 (56%), Gaps = 17/200 (8%)
Query: 31 QRESERKKER-----REREK-RKREREKERKRERGKKEKKKRKKRERGKERER---KRKE 81
+RE ER+KE+ ++R+K R+++REK+++++R ++E++K +++R KE+E+ K KE
Sbjct: 400 EREKEREKEKERGKNKDRDKEREKDREKDKEKDR-EREREKEHEKDRDKEKEKEQDKEKE 458
Query: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141
REK R + +++R+K KK + RR R +ER+ R + R R K ++K
Sbjct: 459 REKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRK 518
Query: 142 KRRKERKREKERGKRERKRKKRK---KEEREKKRERNRKERKKERERKERRERKKERKKE 198
R R R K+++KR+K + E RE++R + ++ +R+ KE+ E+ KE
Sbjct: 519 SSRSPSPR--SRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKE 576
Query: 199 RRKKKERKKDRKTDRQTDSQ 218
+ KE D ++ D +
Sbjct: 577 KEHNKE--PDSSVSKEVDDK 594
Score = 82.4 bits (202), Expect = 4e-16
Identities = 49/181 (27%), Positives = 90/181 (49%), Gaps = 8/181 (4%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
+ E +R KE+ + + +++EREK+R +E +K KK +K R + R+ R R+ RR
Sbjct: 440 EHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRR 499
Query: 91 EKERR-----KRKKEKKKRERKQRGRRERKKKKERKEREREN-KQRRERKRK-KRRKKKR 143
+ R + K K++ + R R KK +++E+ER++ +RRER+R RK
Sbjct: 500 RRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSN 559
Query: 144 RKERKREKERGKRERKRKKRKKE-EREKKRERNRKERKKERERKERRERKKERKKERRKK 202
++ K + E+ K K+ KE + +E + K+ + E K + + +E
Sbjct: 560 DRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLST 619
Query: 203 K 203
K
Sbjct: 620 K 620
Score = 69.7 bits (169), Expect = 3e-12
Identities = 45/175 (25%), Positives = 81/175 (46%), Gaps = 35/175 (20%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKK---------------RERGKER 75
+RE E +K+R + +++++++EKER+++R K+ +KRKK R R R
Sbjct: 436 EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSR 495
Query: 76 ERKRKERE------------KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKER 123
ER+R+ K++ R R + KK+KK+ +ER ER+ER
Sbjct: 496 ERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR-------EKERDHISERRER 548
Query: 124 ERENKQRR-ERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRK 177
ER R+ R + K ++ +EKE K ++ ++++ R K
Sbjct: 549 ERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 603
Score = 42.7 bits (99), Expect = 3e-04
Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 5/111 (4%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKK-RERGKERER--KRKEREKQR 86
+ RE R++ R + + +RK R + + KK ++R KER+ +R+ERE+
Sbjct: 493 SSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERST 552
Query: 87 KERREKERR--KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135
R+ R K K EK K++ + KE + ++ R E +
Sbjct: 553 SMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 603
Score = 41.6 bits (96), Expect = 8e-04
Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 9/105 (8%)
Query: 123 RERENKQRRERKRKKRRKKKRRKERKREKER-GKRERKRKKRKKEEREKKRERNRKERKK 181
+E E +R R+ + E + ER G R R + K K R ++ + K
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSK 332
Query: 182 ERERKERRER--KKERK------KERRKKKERKKDRKTDRQTDSQ 218
R R R R +K+R+ K+R K +ER+K R D +
Sbjct: 333 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKR 377
Score = 41.2 bits (95), Expect = 0.001
Identities = 25/113 (22%), Positives = 52/113 (46%), Gaps = 1/113 (0%)
Query: 21 SCSHISKPCTQRESERKKERREREKRKREREKERKRERGK-KEKKKRKKRERGKERERKR 79
S S P T + +RK R + + +++K+R++ER E+++R++ ++ R
Sbjct: 502 SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDR 561
Query: 80 KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE 132
+EK K + ++ KE K+ ++ + +E K + N Q E
Sbjct: 562 DGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNE 614
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 127 bits (318), Expect = 1e-29
Identities = 77/237 (32%), Positives = 130/237 (54%), Gaps = 21/237 (8%)
Query: 7 SRAAVKLNTELQMVSCSHISKPCTQRESERKKERRER---EKRKREREKERKRERGKKEK 63
SR++ K ++ + H S+ + S +K RR + +KR + RE+ + R R
Sbjct: 200 SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRD 259
Query: 64 KKRKKRERGKERER-KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE 122
K++ RE+ KE+ER K K+REK+R+ +E+E+ K + + K R++++ RE+ K+K+R E
Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDR-E 318
Query: 123 RERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERN--RKERK 180
RERE + E+ R K ++K++ KE++REK+R K +++K+ K+ R R N R+ R
Sbjct: 319 RERE--KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRS 376
Query: 181 KERERKERRERKKERKKERRK------------KKERKKDRKTDRQTDSQVFRPLRE 225
RER+ RR R R K + KKD+K +++ D R RE
Sbjct: 377 SSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERE 433
Score = 126 bits (317), Expect = 2e-29
Identities = 67/202 (33%), Positives = 118/202 (58%), Gaps = 8/202 (3%)
Query: 32 RESERKKERREREKRKREREKERKRERGK---KEKKKRKKRERGKERERKRKEREKQRKE 88
+E ER KE+ ++R+RE+E+E+++ERGK ++K++ K RE+ KE++R+R EREK+ ++
Sbjct: 269 KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER-EREKEHEK 327
Query: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
R+KE+ K + ++K+RE+ + + K+KK++K R R R + ++RR+ R
Sbjct: 328 DRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR-RSRSSSRERRRRRS 386
Query: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
R R R K KRK R RN+K++K+E+ER ER++ + +K +D
Sbjct: 387 RSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRD 446
Query: 209 RKTDRQTDSQVFRPLRESAFNR 230
K + +S L+E N+
Sbjct: 447 GKEKLEKNS---TSLKEKEHNK 465
Score = 122 bits (307), Expect = 3e-28
Identities = 67/181 (37%), Positives = 111/181 (61%), Gaps = 11/181 (6%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
ES + ER K R R R + R + R+KR + K R R ++K+RR
Sbjct: 180 ESGKSNER----KGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRS 235
Query: 93 ERRKRKKEKKKRERKQRGR-RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151
+ +K+ K + RK R R R K+K+ +E+ +E ++ +E+ R+K R+ R KER++EK
Sbjct: 236 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERE--REKEREKEK 293
Query: 152 ERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKT 211
ERGK + + K+R+K +REK +E K+R++ERE++ ++R KE++KE+ K+KER+KDR
Sbjct: 294 ERGKNKDRDKEREK-DREKDKE---KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 349
Query: 212 D 212
+
Sbjct: 350 E 350
Score = 121 bits (303), Expect = 8e-28
Identities = 64/188 (34%), Positives = 120/188 (63%), Gaps = 7/188 (3%)
Query: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR-KEREKQ 85
+P + + +ERK R R + R + R K+ + K + R + R R++ + R K
Sbjct: 178 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKS 237
Query: 86 RKERREKERRKRKKEKKKRER-KQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKR 143
++R K R +RK + R K++ RE+ K+KER KE++RE ++ RE++R+K +++ +
Sbjct: 238 PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 297
Query: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
K+R +E+E+ RE+ ++K ++ EREK+ E++R +++KE+E+ + +ER+K+R KE +K
Sbjct: 298 NKDRDKEREKD-REKDKEKDREREREKEHEKDR-DKEKEKEQDKEKEREKDRSKEIDEK- 354
Query: 204 ERKKDRKT 211
RKKD+K+
Sbjct: 355 -RKKDKKS 361
Score = 112 bits (280), Expect = 4e-25
Identities = 65/203 (32%), Positives = 112/203 (55%), Gaps = 11/203 (5%)
Query: 25 ISKPCTQRESERKKERREREKRKREREK----ERKRERGKKEKKKRKKRERGKERERKRK 80
I KP KE E KR RE + + E GK ++K + + +
Sbjct: 144 IVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSS 203
Query: 81 EREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR-- 138
+ R++R + + R R + + +K R R + KK K RER + R R KR
Sbjct: 204 SKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD 263
Query: 139 -RKKKRRKERKREKERGK-RERKRKKRKKEEREKKRERNR---KERKKERERKERRERKK 193
R+K + KER +EK+R K RER++++ K++ER K ++R++ K+R+K++E+ RER+K
Sbjct: 264 TREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREK 323
Query: 194 ERKKERRKKKERKKDRKTDRQTD 216
E +K+R K+KE+++D++ +R+ D
Sbjct: 324 EHEKDRDKEKEKEQDKEKEREKD 346
Score = 111 bits (278), Expect = 6e-25
Identities = 58/193 (30%), Positives = 116/193 (60%), Gaps = 4/193 (2%)
Query: 34 SERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93
S+ + + +RKR + K R R + +++ +R +++ K RE+++ R
Sbjct: 198 SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS 257
Query: 94 RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153
R KRK ++K + K+R + E+ ++KER ERE+E ++ +ER + K R K+R K+R+++KE+
Sbjct: 258 RDKRKDTREKIKEKERVK-EKDREKER-EREKEREKEKERGKNKDRDKEREKDREKDKEK 315
Query: 154 GKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDR 213
RER+R+K +++R+K++E+ ++++KERE+ +E ++RKK+++ + + + R
Sbjct: 316 -DREREREKEHEKDRDKEKEK-EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRR 373
Query: 214 QTDSQVFRPLRES 226
S R R S
Sbjct: 374 SRSSSRERRRRRS 386
Score = 104 bits (260), Expect = 7e-23
Identities = 61/200 (30%), Positives = 113/200 (56%), Gaps = 17/200 (8%)
Query: 31 QRESERKKER-----REREK-RKREREKERKRERGKKEKKKRKKRERGKERER---KRKE 81
+RE ER+KE+ ++R+K R+++REK+++++R ++E++K +++R KE+E+ K KE
Sbjct: 284 EREKEREKEKERGKNKDRDKEREKDREKDKEKDR-EREREKEHEKDRDKEKEKEQDKEKE 342
Query: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141
REK R + +++R+K KK + RR R +ER+ R + R R K ++K
Sbjct: 343 REKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRK 402
Query: 142 KRRKERKREKERGKRERKRKKRK---KEEREKKRERNRKERKKERERKERRERKKERKKE 198
R R R K+++KR+K + E RE++R + ++ +R+ KE+ E+ KE
Sbjct: 403 SSRSPSPR--SRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKE 460
Query: 199 RRKKKERKKDRKTDRQTDSQ 218
+ KE D ++ D +
Sbjct: 461 KEHNKE--PDSSVSKEVDDK 478
Score = 82.4 bits (202), Expect = 4e-16
Identities = 49/181 (27%), Positives = 90/181 (49%), Gaps = 8/181 (4%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
+ E +R KE+ + + +++EREK+R +E +K KK +K R + R+ R R+ RR
Sbjct: 324 EHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRR 383
Query: 91 EKERR-----KRKKEKKKRERKQRGRRERKKKKERKEREREN-KQRRERKRK-KRRKKKR 143
+ R + K K++ + R R KK +++E+ER++ +RRER+R RK
Sbjct: 384 RRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSN 443
Query: 144 RKERKREKERGKRERKRKKRKKE-EREKKRERNRKERKKERERKERRERKKERKKERRKK 202
++ K + E+ K K+ KE + +E + K+ + E K + + +E
Sbjct: 444 DRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLST 503
Query: 203 K 203
K
Sbjct: 504 K 504
Score = 69.7 bits (169), Expect = 3e-12
Identities = 45/175 (25%), Positives = 81/175 (46%), Gaps = 35/175 (20%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKK---------------RERGKER 75
+RE E +K+R + +++++++EKER+++R K+ +KRKK R R R
Sbjct: 320 EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSR 379
Query: 76 ERKRKERE------------KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKER 123
ER+R+ K++ R R + KK+KK+ +ER ER+ER
Sbjct: 380 ERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR-------EKERDHISERRER 432
Query: 124 ERENKQRR-ERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRK 177
ER R+ R + K ++ +EKE K ++ ++++ R K
Sbjct: 433 ERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 487
Score = 42.7 bits (99), Expect = 3e-04
Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 5/111 (4%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKK-RERGKERER--KRKEREKQR 86
+ RE R++ R + + +RK R + + KK ++R KER+ +R+ERE+
Sbjct: 377 SSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERST 436
Query: 87 KERREKERR--KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135
R+ R K K EK K++ + KE + ++ R E +
Sbjct: 437 SMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 487
Score = 41.6 bits (96), Expect = 8e-04
Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 9/105 (8%)
Query: 123 RERENKQRRERKRKKRRKKKRRKERKREKER-GKRERKRKKRKKEEREKKRERNRKERKK 181
+E E +R R+ + E + ER G R R + K K R ++ + K
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSK 216
Query: 182 ERERKERRER--KKERK------KERRKKKERKKDRKTDRQTDSQ 218
R R R R +K+R+ K+R K +ER+K R D +
Sbjct: 217 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKR 261
Score = 41.2 bits (95), Expect = 0.001
Identities = 25/113 (22%), Positives = 52/113 (46%), Gaps = 1/113 (0%)
Query: 21 SCSHISKPCTQRESERKKERREREKRKREREKERKRERGK-KEKKKRKKRERGKERERKR 79
S S P T + +RK R + + +++K+R++ER E+++R++ ++ R
Sbjct: 386 SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDR 445
Query: 80 KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE 132
+EK K + ++ KE K+ ++ + +E K + N Q E
Sbjct: 446 DGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNE 498
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 122 bits (305), Expect = 4e-28
Identities = 68/202 (33%), Positives = 112/202 (55%), Gaps = 19/202 (9%)
Query: 31 QRES-ERKKERR----------EREKRKREREKERKRERGKKEKKKRKKRERGKERER-K 78
+RE+ ER+KERR R R RER + R R R +K ++ + RER KE ER +
Sbjct: 305 EREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGR 364
Query: 79 RKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138
R++R+ ++ E+E+ + + ++ +E++ RG E KK KE K+ R +R+ K++K+
Sbjct: 365 RRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKK 424
Query: 139 RKKKRRKERK-----REKERGKRERKRKKRK--KEEREKKRERNRKERKKERERKERRER 191
+ R +ERK R + GKR R R K K K + E K + N++ R + R + E+
Sbjct: 425 HSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEK 484
Query: 192 KKERKKERRKKKERKKDRKTDR 213
K+R+ K+K RK+ R +R
Sbjct: 485 SKKREHSPSKEKSRKRSRSKER 506
Score = 121 bits (304), Expect = 6e-28
Identities = 66/207 (31%), Positives = 113/207 (54%), Gaps = 18/207 (8%)
Query: 25 ISKPCTQRESERKKER------REREKRKREREKERKRERGKKEKKKRKKRERGKERER- 77
+ + +RE ER++ R R R RER + R R R +K ++ + RER KE ER
Sbjct: 304 LEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERG 363
Query: 78 KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKK 137
+R++R+ ++ E+E+ + + ++ +E++ RG E KK KE K+ R +R+ K++K
Sbjct: 364 RRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEK 423
Query: 138 RRKKKRRKERK-----REKERGKRERKRKKRK--KEEREKKRERNRKERKKERERKERRE 190
+ + R +ERK R + GKR R R K K K + E K + N++ R + R + E
Sbjct: 424 KHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVE 483
Query: 191 RKKERK----KERRKKKERKKDRKTDR 213
+ K+R+ KE+ +K+ R K+R R
Sbjct: 484 KSKKREHSPSKEKSRKRSRSKERSHKR 510
Score = 112 bits (281), Expect = 3e-25
Identities = 64/205 (31%), Positives = 109/205 (53%), Gaps = 12/205 (5%)
Query: 32 RESERKKER---REREKRKREREKERKRERGKKEKK---KRKKRERGKERERKRKEREKQ 85
RE R + R R+ ++R R+RE+E++ ERG++ + K + ER KERER R ER K+
Sbjct: 333 RERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSR-ERSKE 391
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR-RERKRKKRRKKKRR 144
++ R E E +K K++K R + R +K+KK + R RE K R R R R ++ + R
Sbjct: 392 QRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSR 451
Query: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE 204
+ K K + + + K KR + + + + K +K+E + + RK+ R KER K++
Sbjct: 452 SKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRD 511
Query: 205 RKKDR----KTDRQTDSQVFRPLRE 225
+ K DR+ + + +E
Sbjct: 512 HSDSKDQSDKHDRRRSQSIEQESQE 536
Score = 109 bits (272), Expect = 3e-24
Identities = 60/183 (32%), Positives = 102/183 (55%), Gaps = 9/183 (4%)
Query: 32 RESERKKERREREKRKREREKERKRER-----GKKEKKKRKKRERGKER---ERKRKERE 83
R ER++ R R R R R R G ++ ER KER ER+ KERE
Sbjct: 253 RHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKERE 312
Query: 84 KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKR 143
K+R+ R +R ++ + RER + R R +K +R++R+RE ++ ER R++ R +
Sbjct: 313 KERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDK 372
Query: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
+ +REKER +R R+R K ++ E + +++++++ R R ++R+ KKE+K R + +
Sbjct: 373 ERGNEREKER-ERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSR 431
Query: 204 ERK 206
ERK
Sbjct: 432 ERK 434
Score = 105 bits (263), Expect = 3e-23
Identities = 63/207 (30%), Positives = 109/207 (52%), Gaps = 14/207 (6%)
Query: 21 SCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKR-------ERGK 73
S S P R +E RE E+E++R+R ++E K+R+K +RG
Sbjct: 266 SLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGL 325
Query: 74 ERERKR-KEREKQRKERREKERRKRKKEKKKRERKQRG-RRERKKKKER-KERERENKQR 130
ER R R +ER + R R+++ +R +++++ + +RG RR+R KER ERE+E ++
Sbjct: 326 ERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERS 385
Query: 131 RERKRKKRRK----KKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERK 186
RER +++R + +K+ KE K ++ +R KK KK R + RER + R + R
Sbjct: 386 RERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAG 445
Query: 187 ERRERKKERKKERRKKKERKKDRKTDR 213
+R + + K + K + ++K K R
Sbjct: 446 KRSRSRSKEKSSKHKNESKEKSNKRSR 472
Score = 105 bits (262), Expect = 4e-23
Identities = 56/185 (30%), Positives = 98/185 (52%), Gaps = 7/185 (3%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER--- 89
E +R ERR +R R R + R+ +E+E+QR ER
Sbjct: 250 EIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAK 309
Query: 90 -REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
REKERR+ + + ER++ RER + + R + +++ R+R+R+K ++ RR++R
Sbjct: 310 EREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRD 369
Query: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKE---RRERKKERKKERRKKKER 205
+KERG K ++R +E +++R R E KK +E K+ R+ K++ KKE++ + R
Sbjct: 370 YDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSR 429
Query: 206 KKDRK 210
++RK
Sbjct: 430 SRERK 434
Score = 105 bits (261), Expect = 6e-23
Identities = 56/190 (29%), Positives = 102/190 (53%), Gaps = 7/190 (3%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
R+ ER+KE +R R+ +KER ER EK++ + RER KE+ + + EK+ KE ++
Sbjct: 352 RDREREKENERGRRRDRDYDKERGNER---EKERERSRERSKEQRSRGEVEEKKHKEDKD 408
Query: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151
R + K K+E+K R R++K + R R N +R R R K + K + E K +
Sbjct: 409 DRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSR-NAGKRSRSRSKEKSSKHKNESKEKS 467
Query: 152 ERGKRERKRKKRKKEEREKKRERN-RKERKKERERKERRERKKER--KKERRKKKERKKD 208
+ R + + E+ KKRE + KE+ ++R R + R K++ K++ K +R++
Sbjct: 468 NKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRS 527
Query: 209 RKTDRQTDSQ 218
+ ++++ +
Sbjct: 528 QSIEQESQEK 537
Score = 103 bits (257), Expect = 2e-22
Identities = 56/194 (28%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
+RE E ++ RR +ER ER++ER + ++ +++R RG+ E+K KE + R+ R
Sbjct: 355 EREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRD 414
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK-KRRKKKRRKERKR 149
+K R KKEKK + R R+ R + + R +R + +E+ K K K++ +R R
Sbjct: 415 DK--RDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSR 472
Query: 150 EKERGKRERKRKKRKKE---EREKKRERNR-KERKKERERKERRERKKERKKERRKKKER 205
+G+ + K +K+E +EK R+R+R KER +R+ + +++ + + R + E+
Sbjct: 473 SGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQ 532
Query: 206 KKDRKTDRQTDSQV 219
+ K + D V
Sbjct: 533 ESQEKQHKNKDETV 546
Score = 93.2 bits (230), Expect = 2e-19
Identities = 56/196 (28%), Positives = 105/196 (53%), Gaps = 24/196 (12%)
Query: 42 EREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRK----- 96
+++ + R R+ ++ + G +E + +R R + R R R+ R R+
Sbjct: 230 DQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSS 289
Query: 97 -------RKKEKKKRERKQRGRRERKKKKERK-----ERERENKQRRERKRKKRRKKK-- 142
R+KE+++ ER+ + RE+++++ R ER R + R R R + R +K
Sbjct: 290 SFDRELEREKERQRLEREAK-EREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGD 348
Query: 143 ---RRKERKREKERG-KRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKE 198
R +ER++E ERG +R+R K + EREK+RER+R+ K++R R E E+K + K+
Sbjct: 349 RRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKD 408
Query: 199 RRKKKERKKDRKTDRQ 214
R+ ++ K+D K +++
Sbjct: 409 DRRHRDDKRDSKKEKK 424
Score = 90.1 bits (222), Expect = 2e-18
Identities = 54/167 (32%), Positives = 91/167 (54%), Gaps = 12/167 (7%)
Query: 61 KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGR------RER 114
+ +K +K + G E + ER + R RR R+ + + R + G RE
Sbjct: 236 RPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDREL 295
Query: 115 KKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRER 174
+++KER+ ERE K+R E++R++ R R ER+R + R ER R + + +R+ R
Sbjct: 296 EREKERQRLEREAKER-EKERRRSRSIDRGLERRRSRSR---ERHRSRSRSRDRKGDRRD 351
Query: 175 NRKERKKERERKERRERK--KERKKERRKKKERKKDRKTDRQTDSQV 219
+ER+KE ER RR+R KER ER K++ER ++R ++++ +V
Sbjct: 352 RDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEV 398
Score = 73.2 bits (178), Expect = 2e-13
Identities = 47/167 (28%), Positives = 90/167 (53%), Gaps = 16/167 (9%)
Query: 73 KERERKRKEREKQRKER--REKERRKRKKEKKKRERKQRGRRERKKKKERKER-----ER 125
K R RK K+ K+ E R ERR+ + ++ ++ RR R + R+ +R
Sbjct: 234 KTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDR 293
Query: 126 ENKQRRERKRKKRRKKKRRKERKREK--ERGKRERKRKKRKKEEREKKRERNRKERKKER 183
E ++ +ER+R +R K+R KER+R + +RG ER+R + ++ R + R R+RK +++R
Sbjct: 294 ELEREKERQRLEREAKEREKERRRSRSIDRGL-ERRRSRSRERHRSRSRSRDRKGDRRDR 352
Query: 184 ERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNR 230
+R+ +E++ ER ++++R D++ + + + R S R
Sbjct: 353 DRE------REKENERGRRRDRDYDKERGNEREKERERSRERSKEQR 393
Score = 69.7 bits (169), Expect = 3e-12
Identities = 48/152 (31%), Positives = 77/152 (50%), Gaps = 16/152 (10%)
Query: 79 RKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138
+K ++Q K R K ++ K+ ++ +R RR R ++ R RR R R
Sbjct: 226 QKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRR---SPRRSRSRSHH 282
Query: 139 RKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNR-------KERKKERERKERRER 191
R+ RE ER K ER+R +R+ +EREK+R R+R + R + RER R R
Sbjct: 283 REGHGSSSFDRELEREK-ERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSR 341
Query: 192 KKERKKERR-----KKKERKKDRKTDRQTDSQ 218
++RK +RR ++KE ++ R+ DR D +
Sbjct: 342 SRDRKGDRRDRDREREKENERGRRRDRDYDKE 373
Score = 57.0 bits (136), Expect = 2e-08
Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 4/119 (3%)
Query: 27 KPCTQRESERKKERRERE----KRKREREKERKRERGKKEKKKRKKRERGKERERKRKER 82
K R ERK R R KR R R KE+ + + K+K KR R + R
Sbjct: 424 KHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVE 483
Query: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141
+ +++E + + RK+ + K +R + K + ++ +R R +E + K+ + K
Sbjct: 484 KSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNK 542
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 120 bits (300), Expect = 2e-27
Identities = 55/210 (26%), Positives = 147/210 (70%), Gaps = 12/210 (5%)
Query: 16 ELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKER 75
+L+ + + + + E ++++ RRE++ R+++ E+ R+++ ++E+++R++++ +
Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336
Query: 76 ERKRKEREKQRKE--RREKERRKR----KKEKKKRERKQRGRRERKKKKERKERERENKQ 129
++ R+E+E++R++ RRE+E +R ++E+++ R+Q+ RRE++ ++E++ R RE +
Sbjct: 337 QQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLR-REQQL 395
Query: 130 RRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER- 188
RRE++ ++ ++ +R ++ +RE++ + ++ R+++++E E+K E+ R+E++ +RE++ER
Sbjct: 396 RREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR 455
Query: 189 ----RERKKERKKERRKKKERKKDRKTDRQ 214
RE + ER ++ R+K++ K+D++ +R+
Sbjct: 456 DWLKREEETERHEQERRKQQLKRDQEEERR 485
Score = 118 bits (296), Expect = 5e-27
Identities = 61/205 (29%), Positives = 142/205 (69%), Gaps = 11/205 (5%)
Query: 31 QRESERKKE---RREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK 87
+RE E ++E RRE+E+ +RE++ R++E ++E++ R++++ +E ++ R+E++ +R+
Sbjct: 340 RREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE-QQLRREQQLRRE 398
Query: 88 ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK-- 145
++ +E++ R++++ +RE++ R ++ ++++E + E++++Q R +R KR +++RR
Sbjct: 399 QQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWL 458
Query: 146 ERKREKERGKRERKRKKRKKEEREKKRERNRK-ERKKERERKERRE----RKKERKKERR 200
+R+ E ER ++ER++++ K+++ E++RER K E ++ RE++ERRE R++E ++E+R
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR 518
Query: 201 KKKERKKDRKTDRQTDSQVFRPLRE 225
K++ +++R R Q R +E
Sbjct: 519 LKRQEEEERLQQRLRSEQQLRREQE 543
Score = 117 bits (292), Expect = 1e-26
Identities = 62/202 (30%), Positives = 139/202 (68%), Gaps = 11/202 (5%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERER----KRKEREKQR 86
+RE + ++E++ R +++ RE+E +R K E+++R++R + ++ ER KR+E ++
Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467
Query: 87 KERREKERRKRKKEKKKRERKQR-GRRERKKKKERKERE--RENKQRRERKRKKRRKKKR 143
++ R K++ KR +E+++RER + ER++++ER+E++ RE ++RRE++ K++ +++R
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER 527
Query: 144 RKERKREKERGKRERKRKKRK--KEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
++R R +++ +RE++ ++ + K E EK+ E+ R+E++ +RE++ERR++ +R++ERR+
Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQ 587
Query: 202 K--KERKKDRKTDRQTDSQVFR 221
+ K +++R R +V R
Sbjct: 588 QRLKREQEERLEQRLKREEVER 609
Score = 115 bits (288), Expect = 4e-26
Identities = 60/221 (27%), Positives = 153/221 (69%), Gaps = 21/221 (9%)
Query: 31 QRESERKKERRER--EKRKREREKERKRERGKKEKKKRKKRERGKERERKRKE---REKQ 85
++E ER++++ ER ++ +RE+++ER+ ++ ++E+++R++++ +E+E +R+E R +Q
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
Query: 86 RKERREKERRKRKKEKKKRE--RKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKR 143
+ERRE++ R+ ++ +++++ R+Q+ RRE++ ++E++ R RE + RRE++ ++ ++ +R
Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR-REQQLRREQQLRREQQLRR 427
Query: 144 RKERKREKERGKRERKRKKRKKEE--------REKKRERNRKERKKERERKERRERKKER 195
+E +R +++ ++ER+ ++ K+E+ RE++ ER+ +ER+K++ ++++ E ++ER
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 196 -----KKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRV 231
++ERR+++ER++ + Q + + R R+ R+
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
Score = 115 bits (287), Expect = 5e-26
Identities = 56/198 (28%), Positives = 141/198 (71%), Gaps = 12/198 (6%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKE--RR 90
E ER++++ RE++ R ++ER+ +R K+++++ + ++R + ++ R+E+E++R++ +R
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552
Query: 91 EKERR---KRKKEKKKRERKQRG----RRERKKKKERKERERENK--QRRERKRKKRRKK 141
E+E+R +R++++ KRE+++R +RE +++++R +RE+E + QR +R+ +R ++
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Query: 142 KRRKERKREKERGKRERKRKKRKKEEREKKRERN-RKERKKERERKERRERKKERKKERR 200
+ R+E++ ++E + ER+++ K EE+E++R++ R+E+++ RE++ +RE ++ER ++R
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRL 672
Query: 201 KKKERKKDRKTDRQTDSQ 218
K++ ++ R+ + + Q
Sbjct: 673 KREHEEERREQELAEEEQ 690
Score = 113 bits (283), Expect = 2e-25
Identities = 53/187 (28%), Positives = 128/187 (68%), Gaps = 4/187 (2%)
Query: 31 QRESERKKERREREKRKREREKERKRERG-KKEKKKRKKRERGKERERKRKEREKQRKER 89
+RE + ++E++ R +++ RE++ +RE+ ++E++ R+++E + ++ +ER +QR +R
Sbjct: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
Query: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
++ERR K +++ ER ++ RR+++ K++++E RE + E + ++ ++++R ++ +R
Sbjct: 450 EQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR 509
Query: 150 EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDR 209
E+E R+++ +++EE E+ ++R R E++ RE++ERRE+ +R++E+R ++ER++ R
Sbjct: 510 EQE---ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
Query: 210 KTDRQTD 216
Q +
Sbjct: 567 LKREQEE 573
Score = 113 bits (282), Expect = 2e-25
Identities = 53/192 (27%), Positives = 139/192 (72%), Gaps = 9/192 (4%)
Query: 31 QRESERKKERREREK--RKRERE---KERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
+ E +R++E +E E+ RK ER+ +ER+ E ++++ +R+++ R K+ E +R+++E++
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
R+++ +E+++ ++E++ R R+Q RRE++ ++E++E RE + RRE++ ++R ++ RR+
Sbjct: 322 REQQERREQQEERREQQLR-REQEERREQQLRREQEEERREQQLRREQEEERREQQLRRE 380
Query: 146 ERKREKERGKRE---RKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKK 202
++ R +++ +RE R+ ++ ++E++ ++ ++ R+E++ RE++ RRE+++ER +++ ++
Sbjct: 381 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440
Query: 203 KERKKDRKTDRQ 214
+ R++ K +++
Sbjct: 441 ERREQRLKREQE 452
Score = 113 bits (282), Expect = 2e-25
Identities = 59/217 (27%), Positives = 139/217 (64%), Gaps = 11/217 (5%)
Query: 8 RAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKR-KREREKER----KRERGKKE 62
R +L E Q+ + + + E+K E+ RE+R KRE+E+ R + E ++
Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467
Query: 63 KKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE 122
+++R+K++ +++E +R+ER + +E +E+++R++++ +RE+++R R +R K++E +E
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEER-REQRLKRQEEEE 526
Query: 123 R-----ERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRK 177
R E + RRE++ ++ + KR +E++ E+ER ++ KR++ ++ ++ KRE R+
Sbjct: 527 RLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERR 586
Query: 178 ERKKERERKERRERKKERKKERRKKKERKKDRKTDRQ 214
+++ +RE++ER E++ +R++ R ++E +++++ R+
Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEERREQRLKRE 623
Score = 113 bits (282), Expect = 2e-25
Identities = 61/194 (31%), Positives = 132/194 (68%), Gaps = 14/194 (7%)
Query: 31 QRESERKKER--REREKR----KREREKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
+ E ER+++R RE+E+R KRE E ER + +K++ KR + E +ER K +E E+
Sbjct: 437 KHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEER 496
Query: 85 -QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKR 143
+++ERRE++ R+ ++E++++ K++ ER +++ R E++ +Q R++ +R++++
Sbjct: 497 REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEK 556
Query: 144 RKERKREKERGKRERKRK-----KRKKEEREKKRERNRKERKKERERKERRER--KKERK 196
R E++R ++R KRE++ + KR++E R+++ +R ++ER ++R ++E ER ++ER+
Sbjct: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR 616
Query: 197 KERRKKKERKKDRK 210
++R K++E +++R+
Sbjct: 617 EQRLKREEPEEERR 630
Score = 112 bits (281), Expect = 3e-25
Identities = 50/194 (25%), Positives = 134/194 (69%), Gaps = 6/194 (3%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKER--EKQRKE 88
Q E E++ +RE RK E + + + + ++E ++ +++ R ER+ R+ER E+Q+++
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
R +E++ R+K++++R +Q RRE+++++E++E RE + RRE++ ++ ++ +R +E +
Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358
Query: 149 REKERGKRERKRKKR----KKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE 204
R +++ +RE++ ++R ++E++ ++ ++ R+E++ RE++ RRE++ R+++ R++++
Sbjct: 359 RREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Query: 205 RKKDRKTDRQTDSQ 218
+++++ R+ + +
Sbjct: 419 LRREQQLRREQEEE 432
Score = 112 bits (281), Expect = 3e-25
Identities = 53/186 (28%), Positives = 131/186 (70%), Gaps = 4/186 (2%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERE--RKRKEREKQRKE 88
+ E+ER ++ R +++ KR++E+ER+ K E+++R++++ +E++ R+++ER +QR +
Sbjct: 461 EEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLK 520
Query: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
R+E+E R +++ + +++ ++ R++ +R+E +R ++RRE++ K+ ++++R + K
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLK 580
Query: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
RE+ER R+++ K+ ++E E++ +R ER ++ ER+E+R +++E ++ERR++ + ++
Sbjct: 581 REEER--RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE 638
Query: 209 RKTDRQ 214
++ RQ
Sbjct: 639 QEERRQ 644
Score = 112 bits (281), Expect = 3e-25
Identities = 64/232 (27%), Positives = 149/232 (64%), Gaps = 31/232 (13%)
Query: 31 QRESERKKE--RREREKRKRER-----EKERKRERGKKEKKKRKKRERGKERERKRKERE 83
+ E ER+K+ +R++E+ +RER E+ER+ ++ ++E++ R+++E +E+ KR+E E
Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE 525
Query: 84 KQRKERREKERRKRKKEKKKRE----RKQRGRRERKKKKERKERERENKQ----RRERKR 135
++ ++R E++ R++++++RE R++ R E++++++R +RE+E ++ +RE +R
Sbjct: 526 ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
Query: 136 KKRRKKKRRKER------KREKERGKRERKRKKR-KKEEREKKR---------ERNRKER 179
+++R K+ ++ER + E ER ++E +R++R K+EE E++R + R+++
Sbjct: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
Query: 180 KKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRV 231
+ RE++ERRE++ +R++E + ++R K + + + ++ +E A R+
Sbjct: 646 QLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERI 697
Score = 112 bits (279), Expect = 5e-25
Identities = 55/195 (28%), Positives = 139/195 (71%), Gaps = 14/195 (7%)
Query: 33 ESERKKERRER-------EKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
+ E +KE R+R E++ +E E +R+RE ++E++ RK + RER+ +E+++Q
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 86 RKERREKERRKRKKEKKKRE---RKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK 142
R R ++ RRK+++E+++++ R+Q+ RRE+++++ ++ RE ++RRE++ ++ ++++
Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358
Query: 143 RRKE---RKREKERGKRERKRKKRKKEEREKKRERN-RKERKKERERKERRERKKERKKE 198
RR++ R++E+ER +++ +R+++ + E++ +RE+ R+E++ RE++ RRE++ R+++
Sbjct: 359 RREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Query: 199 RRKKKERKKDRKTDR 213
R++++ +++++ +R
Sbjct: 419 LRREQQLRREQEEER 433
Score = 111 bits (278), Expect = 6e-25
Identities = 60/210 (28%), Positives = 128/210 (60%), Gaps = 10/210 (4%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Q E ER ++R E++ R ++ER+ + K+E++KR ++ER ++R ++ +E + + +R
Sbjct: 522 QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR 581
Query: 91 EKERR----KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
E+ERR KR++E++ +R +R ER +++ER+E+ + ++ E +R++ K + ++E
Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641
Query: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER------RERKKERKKERR 200
R++++ R +++ +R++R K E E++R R +R+ E ER+E+ +E+ +ER K R
Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701
Query: 201 KKKERKKDRKTDRQTDSQVFRPLRESAFNR 230
K + + + + D + RP ++ R
Sbjct: 702 PKWQWQLESEADARQSKVYSRPRKQEGQRR 731
Score = 110 bits (276), Expect = 1e-24
Identities = 53/217 (24%), Positives = 138/217 (63%), Gaps = 18/217 (8%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
++E ER++++ RE+ + RE++ +RE+ + +++ ++ ++ + ++ R+E++ +R+++
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 413
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
+E++ R++++ +RE+++ R E+K ++ER+E+ + +Q R KR ++ R E++R
Sbjct: 414 RREQQLRREQQLRREQEEE-RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR 472
Query: 151 KERGKRERKRKKR----KKEEREKKRERNRKERKKERERKERRERKKERKKER------- 199
K++ KR+++ ++R K EE E++ ++ R+E++ RE++ERRE++ +R++E
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRL 532
Query: 200 ------RKKKERKKDRKTDRQTDSQVFRPLRESAFNR 230
R+++E ++++ R+ + ++ + RE R
Sbjct: 533 RSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
Score = 110 bits (276), Expect = 1e-24
Identities = 55/194 (28%), Positives = 127/194 (65%), Gaps = 10/194 (5%)
Query: 31 QRESERKKERREREKRKREREKERKRE----RGKKEKKKRKKRERGKERERKRKEREKQR 86
QRE K+ R+E+E++ RE E+ ++ E R ++EK++R++RER +++K +++E+Q
Sbjct: 914 QREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL 973
Query: 87 KERREKERRKRKKEKKKRERKQRGR------RERKKKKERKERERENKQRRERKRKKRRK 140
++RR++++EKK RE ++ + RE ++K+ R+E ER+ +++ E ++++ +
Sbjct: 974 LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQL 1033
Query: 141 KKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERR 200
+ +E++R +ER ++ R+ ++ ++EE + E R++E ER+ R+E + ++++E+
Sbjct: 1034 LREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL 1093
Query: 201 KKKERKKDRKTDRQ 214
++E +K R+ +R+
Sbjct: 1094 LREEPEKRRRQERE 1107
Score = 110 bits (275), Expect = 1e-24
Identities = 55/219 (25%), Positives = 144/219 (65%), Gaps = 10/219 (4%)
Query: 16 ELQMVSCS-HISKPCTQRESERKKERREREKRKREREKERKRERG-----KKEKKKRKKR 69
E Q+ SC H ++ E R++E E ++ RE +++++RER ++E+K+ +KR
Sbjct: 190 EEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKR 249
Query: 70 ER--GKERERKRKEREKQRKERREKERRKRKKEKK--KRERKQRGRRERKKKKERKERER 125
E KE E+ ++E ++++E +E+E + RK E++ +RER++ +++++ ++E++ R +
Sbjct: 250 ETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK 309
Query: 126 ENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERER 185
+ ++RRE++ ++R +++RR++++ +E+ R + ++R+++ R ++ E R+++ + +
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369
Query: 186 KERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLR 224
+ERRE++ R+++ R++++ +++++ R+ + + LR
Sbjct: 370 EERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 408
Score = 109 bits (272), Expect = 3e-24
Identities = 65/194 (33%), Positives = 122/194 (62%), Gaps = 16/194 (8%)
Query: 32 RESERKKERREREKRKREREK------------ERKRERGKKEKKKRKKRERGKERERK- 78
RE K+ R+ERE++ R+ +K KR R ++EKK R++ E +E E+
Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
Query: 79 RKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138
R+EREK+R R+E ER+ RKK++ ++E +Q R ER+K++ +ERER+ ++ E ++++
Sbjct: 1005 REEREKRR--RQEWERQYRKKDELQQEEEQLLREEREKRR-LQERERQYREEEELQQEEE 1061
Query: 139 RKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKE 198
+ +E +R +E ++ RK ++ ++EE + RE K R++ERER+ R E + ++++E
Sbjct: 1062 QLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEE 1121
Query: 199 RRKKKERKKDRKTD 212
+ ++ER+K R+ +
Sbjct: 1122 QLLREEREKRRRQE 1135
Score = 108 bits (270), Expect = 5e-24
Identities = 55/188 (29%), Positives = 120/188 (63%), Gaps = 4/188 (2%)
Query: 26 SKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERK-RKEREK 84
+KP Q + ++++ + E+ + +RE+ KR R ++E++ R++ + +E E+ R+EREK
Sbjct: 891 AKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREK 950
Query: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR 144
+R++ RE++ RK KK ++K E+ E +K+ R+ERE++ ++ E ++++ + +
Sbjct: 951 RRRQERERQYRKDKKLQQKEEQLLG---EEPEKRRRQEREKKYREEEELQQEEEQLLREE 1007
Query: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE 204
+E++R +E ++ RK+ + ++EE + RE K R +ERER+ R E + ++++E+ +E
Sbjct: 1008 REKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEE 1067
Query: 205 RKKDRKTD 212
R+ R+ +
Sbjct: 1068 RETRRRQE 1075
Score = 108 bits (269), Expect = 7e-24
Identities = 56/188 (29%), Positives = 118/188 (62%), Gaps = 5/188 (2%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
+E R +E+R +K + + E+ERKR R K + + KE++ ++E E+ ++E RE
Sbjct: 860 QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREERE 919
Query: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR-----KE 146
K RR+ ++ + + E + + E+ ++ER++R R+ ++R+ RK KK ++K+ + E
Sbjct: 920 KRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPE 979
Query: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
++R +ER K+ R+ ++ ++EE + RE K R++E ER+ R++ + ++++E+ ++ER+
Sbjct: 980 KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREERE 1039
Query: 207 KDRKTDRQ 214
K R +R+
Sbjct: 1040 KRRLQERE 1047
Score = 107 bits (268), Expect = 9e-24
Identities = 64/215 (29%), Positives = 138/215 (64%), Gaps = 18/215 (8%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Q+E +R++ERR ++R R +E + ER ++++ KR+ R+ +E++ R+ERE++R+ R+
Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRR-RQ 1332
Query: 91 EKERRKRKKEKKKRERKQRG-RRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
E +R+ R++E+ +ER+++ RR+ + +K R+E R +Q R+ +++R +++ +ERK
Sbjct: 1333 ETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKF 1392
Query: 150 EKERG-----------KRERKRKKRKKEEREKKRERNRKERKKERE-RKERRERK----K 193
KE +++R RK R++E++ ++ER+RK R++E++ R++ RERK +
Sbjct: 1393 LKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452
Query: 194 ERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAF 228
++ ++ R +K R++++ + + Q+ R R+ F
Sbjct: 1453 QQLRQERHRKFREEEQLLQEREEQQLHRQERDRKF 1487
Score = 107 bits (267), Expect = 1e-23
Identities = 52/199 (26%), Positives = 126/199 (63%), Gaps = 13/199 (6%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
+RE E++ E+ RE+R + ++ER+ + K+E+++R++R + ++ ER + +++ ER
Sbjct: 551 KREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL 610
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
E+E +R++++ KRE + RR++ K E +E R+ + RRE++ ++ ++ KR +E +R
Sbjct: 611 EQE--ERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL 668
Query: 151 KERGKRERKRKKRKKEEREKKRERNRKERK-----------KERERKERRERKKERKKER 199
++R KRE + ++R++E E+++E+ R+ K E + ++ + + RK+E
Sbjct: 669 EQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEG 728
Query: 200 RKKKERKKDRKTDRQTDSQ 218
+++++ +++++ R+++ Q
Sbjct: 729 QRRRQEQEEKRRRRESELQ 747
Score = 106 bits (265), Expect = 2e-23
Identities = 66/232 (28%), Positives = 137/232 (59%), Gaps = 34/232 (14%)
Query: 31 QRESERK--KERREREKRKREREKERKR---ERGKKEKKKRKKRERGKERERKRKEREKQ 85
QR S R +E+RER+ R ER++ +R E +KE+++R++RER KE + +E + Q
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ 841
Query: 86 RKERR----------EKERRKRKKEKKKRERKQRGRRERKKKKER---------KERERE 126
R+ER ++++ +R+ ++++R++K R + E ++K+ R +E+ R+
Sbjct: 842 RRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRK 901
Query: 127 NKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERK 186
+Q + + ++ ++++R K R++E+ER RE ++ ++EE + RE K R++ERER+
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQERQYRE--EEQLQQEEEQLLREEREKRRRQERERQ 959
Query: 187 ERRERKKERKK--------ERRKKKERKKDRKTDRQTDSQVFRPLRESAFNR 230
R+++K ++K+ E+R+++ER+K + + + + + LRE R
Sbjct: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR 1011
Score = 106 bits (264), Expect = 3e-23
Identities = 53/209 (25%), Positives = 136/209 (65%), Gaps = 25/209 (11%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRE-----RGKERER-------- 77
+ +SE+++ +R++++R+ E R+R+ ++ +++R + E +G E E
Sbjct: 152 EEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLR 211
Query: 78 -------KRKEREKQRKERREKERRKRKKEKKKRERKQRG---RRERKKKKERKEREREN 127
+RK RE+++++RRE++ R ++E++K RK+ + E K ++E +R+RE
Sbjct: 212 RRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQREL 271
Query: 128 KQRRERKRKKRRKKKRRK--ERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERER 185
++ E+ RK R++ RR+ E +++++R +RE++ +++++EER +++E R+++++ ++
Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQ 331
Query: 186 KERRERKKERKKERRKKKERKKDRKTDRQ 214
+ERRE++ R++E R++++ +++++ +R+
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERR 360
Score = 105 bits (263), Expect = 3e-23
Identities = 63/228 (27%), Positives = 133/228 (58%), Gaps = 30/228 (13%)
Query: 28 PCTQRESERKKERREREKRKR---EREKERKRERGKKEKKKRKKRERGKERERKRKER-- 82
P + + +R+++RREREK + E E+ ++RER ++ +++ + +ER R +++R
Sbjct: 812 PEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRD 871
Query: 83 -------EKQRKERREK-------ERRKRKKEKKKRERKQRGRRERKKKKERKERERENK 128
E++RK RR + + RK+++ +E ++ +RE ++K+ R+E+ER+ +
Sbjct: 872 QKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYR 931
Query: 129 QRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER 188
+ + ++++ + + +E++R +ER ++ RK KK +++E + E K R++ERE+K R
Sbjct: 932 EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYR 991
Query: 189 RER----------KKERKKERRKKKERKKDRKTD-RQTDSQVFRPLRE 225
E ++ER+K RR++ ER+ +K + +Q + Q+ R RE
Sbjct: 992 EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREERE 1039
Score = 103 bits (257), Expect = 2e-22
Identities = 54/219 (24%), Positives = 134/219 (61%), Gaps = 24/219 (10%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK------ 84
Q+ E+++E E E++ ++E+ +R+R +++++ ++R+ +ERE +R E E+
Sbjct: 139 QKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKG 198
Query: 85 ----------QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK 134
Q + R E R++ +E+K+++R++R R ++++E++ R+RE R+E +
Sbjct: 199 HETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE 258
Query: 135 RKKRRKKKRRKERKREKER-GKRERKRKKRKKEEREKKRER-------NRKERKKERERK 186
+ + + +R++E + E+E+ K ER+ +R+++E E++++R RK+ ++ RE++
Sbjct: 259 KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
Query: 187 ERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
E R ++ER++++ +++E++ R+ + + + Q+ R E
Sbjct: 319 EERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357
Score = 103 bits (256), Expect = 2e-22
Identities = 63/219 (28%), Positives = 139/219 (63%), Gaps = 25/219 (11%)
Query: 31 QRESERKKERRERE------KRKREREKERKRERGKKEKKKRKKRERGKERERKRKERE- 83
Q E +R+ E R+R+ +R+R++ +E++RE + E++ +K+ER ++R+R+R++ E
Sbjct: 115 QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQS-EKQERLEQRDRQRRDEEL 173
Query: 84 -KQRKERREKERRKRKKEK----KKRERKQRGRRERKKKKE-----RKERERENKQRRER 133
+QR+E +E+E R+ ++E+ K E ++ E+ +++E RK RE + +QRRER
Sbjct: 174 WRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER 233
Query: 134 K----RKKRRKKKRRKE---RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERK 186
+ +++ K+ R++E RK E++ + E +R++ +EE E+ R+ R+E ++ER+ +
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE 293
Query: 187 ERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
E+++++ R+++ R+K+E ++ + + + + Q R +E
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Score = 103 bits (256), Expect = 2e-22
Identities = 60/208 (28%), Positives = 130/208 (62%), Gaps = 12/208 (5%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Q E E +KE + R+ RK + EK+ RE ++++++++ + +E E+ +ERE+Q R+
Sbjct: 1298 QLEREEQKEAKRRD-RKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQ 1356
Query: 91 EKERRKRKKEKKKRERKQR----GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
E++R+ R++E + +E+ ++ +R R++++ERK + E + R + + ++ R+ + RK
Sbjct: 1357 ERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKF 1416
Query: 147 RKREKERGKRERKRKKRKKEEREKKRERNRK------ERKKERERKERRERKKERKKERR 200
R+ E++ ++ER RK R++E++ +++ER RK + ++ER RK R E + +++E +
Sbjct: 1417 REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQ 1476
Query: 201 KKKERKKDRKTDRQTDSQVFRPLRESAF 228
+ +++DRK + + Q+ R R+ F
Sbjct: 1477 QLHRQERDRKF-LEEEQQLRRQERDRKF 1503
Score = 103 bits (256), Expect = 2e-22
Identities = 65/204 (31%), Positives = 128/204 (62%), Gaps = 16/204 (7%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Q+E++R+ + + EK+ E+E KR R + ++K R++ + +ERE + R+++ ++ R
Sbjct: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFR 1363
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKE------RERENKQRRERKRKKR------ 138
E+E R +++ +K E +QR RR+ +++K KE +ERE + R++R RK R
Sbjct: 1364 EEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQL 1423
Query: 139 -RKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKK 197
R+++ RK R+ E++ ++ER+RK +EE++ ++ER+RK R++E+ +ER E++ R++
Sbjct: 1424 SRQERDRKFREEEQQVRRQERERKF-LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE 1482
Query: 198 ERRKKKERKKDRKTDRQTDSQVFR 221
RK E ++++ RQ + FR
Sbjct: 1483 RDRKFLE--EEQQLRRQERDRKFR 1504
Score = 102 bits (253), Expect = 5e-22
Identities = 66/239 (27%), Positives = 135/239 (56%), Gaps = 38/239 (15%)
Query: 27 KPCTQRESERKKERREREKRKRE-----REKERKRERGKKEKKKRKKRERGKERERK-RK 80
+P +R ER+K+ RE E+ ++E RE+ KR R + E++ RKK E +E E+ R+
Sbjct: 977 EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036
Query: 81 EREKQRKERREK----------------------------ERRKRKKEKKKRERKQRGRR 112
EREK+R + RE+ ER+ RK+E+ ++E +Q R
Sbjct: 1037 EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL-LR 1095
Query: 113 ERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKR 172
E +K+ R+ERER+ ++ E ++++ + + +E++R +E ++ R+ ++ ++EE + R
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
Query: 173 ERNRKERKKERERKERRERKKERKKE---RRKKKERKKDRKTDRQTDSQVFRPLRESAF 228
E K R++E ER+ R E + ++++E R ++++R+++R+ + + ++ R R+ +
Sbjct: 1156 EEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRY 1214
Score = 101 bits (252), Expect = 6e-22
Identities = 62/197 (31%), Positives = 123/197 (62%), Gaps = 18/197 (9%)
Query: 33 ESERKKERREREKRKRE------------REKERKRERGKKEKKKRKKRERGKERER-KR 79
E K+ R+EREK+ RE RE+ KR R + E++ RKK E +E E+ R
Sbjct: 976 EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLR 1035
Query: 80 KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR 139
+EREK+R + E+ER+ R++E+ ++E +Q ER+ ++ R+E ER+ ++ E ++++ +
Sbjct: 1036 EEREKRRLQ--ERERQYREEEELQQEEEQLLGEERETRR-RQELERQYRKEEELQQEEEQ 1092
Query: 140 KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER 199
+ E++R +ER ++ R+ ++ ++EE + RE K R++E ER+ R E + ++++E+
Sbjct: 1093 LLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQ 1152
Query: 200 --RKKKERKKDRKTDRQ 214
R++ E+++ ++ +RQ
Sbjct: 1153 LLREEPEKRRRQELERQ 1169
Score = 101 bits (251), Expect = 8e-22
Identities = 55/205 (26%), Positives = 133/205 (64%), Gaps = 20/205 (9%)
Query: 36 RKKERREREKRKREREK--------------ERKRERGKKEKKKRKKRERGKERERKRKE 81
+++E +ERE+R+ E E+ E + R + + +RK RE +++ R+R++
Sbjct: 176 QRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQD 235
Query: 82 R---EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138
R E++ KE R++E RK+E+K +E + + +RE ++++E+ + + RRER+ +++
Sbjct: 236 RVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQ 295
Query: 139 RKKKRRKER--KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERK 196
++++ R+E+ +R++E +RE++ ++R+++ER +++E R+E++ RE++ERRE++ R+
Sbjct: 296 QQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE-RREQQLRREQEERREQQLRRE 354
Query: 197 KERRKKKERKKDRKTDRQTDSQVFR 221
+E +++++ + + + + + Q+ R
Sbjct: 355 QEEERREQQLRREQEEERREQQLRR 379
Score = 101 bits (251), Expect = 8e-22
Identities = 59/216 (27%), Positives = 134/216 (62%), Gaps = 21/216 (9%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
++E ERK + E++ R +ERE++ +++R +K +++ ++ R +ER+RK +E E+Q + R+
Sbjct: 1385 RQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR-QERDRKFREEEQQVR-RQ 1442
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR- 149
E+ER+ ++E++ R+ + R RE ++ + +E ++ ++Q R+RK + ++ RR+ER R
Sbjct: 1443 ERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRK 1502
Query: 150 -----------------EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERK 192
E+++ R+++++K +EE++ +R+ ++R+++R+RK R E +
Sbjct: 1503 FREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQ 1562
Query: 193 KERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAF 228
+++E ++ +++DRK R + +V R +E F
Sbjct: 1563 LRQEREEQQLSRQERDRKF-RLEEQKVRRQEQERKF 1597
Score = 100 bits (250), Expect = 1e-21
Identities = 65/228 (28%), Positives = 129/228 (56%), Gaps = 33/228 (14%)
Query: 31 QRESERKKERREREKRKREREKER-----------KRERGKKEKKKRKKRERGKERERKR 79
+RESE + + ER R+++ E++R K ERG++ R +ER+ +
Sbjct: 741 RRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRA 800
Query: 80 KER---------EKQRKERREKERRKRKKEKK-KRERKQRGRRERKKKKERKERERENKQ 129
+ER E++ KE+R ++RR+R+KE + E +Q RRER ++ + +E + Q
Sbjct: 801 EERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ 860
Query: 130 RRERKRKKRRKKKRRKERKREKERGK---------RERKRKKR---KKEEREKKRERNRK 177
R R +++RR +K R + + E++R + +E+ RK++ ++EE E +RE K
Sbjct: 861 ERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREK 920
Query: 178 ERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
R++E+ER+ R E + ++++E+ ++ER+K R+ +R+ + + L++
Sbjct: 921 RRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
Score = 100 bits (249), Expect = 1e-21
Identities = 61/231 (26%), Positives = 143/231 (61%), Gaps = 34/231 (14%)
Query: 27 KPCTQRESERKKERREREKRKRERE----------KER--KRERGKKEKKKRKKRERGKE 74
+P ++ E +RR ++++++ERE +ER +R+R +++++ ++R+ +E
Sbjct: 123 EPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQE 182
Query: 75 RERKRKER----------------EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKK 118
RE +R E E+Q + R E R++ +E+K+++R++R R ++++
Sbjct: 183 REERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEE 242
Query: 119 ERKERERENKQRRERKRKKRRKKKRRKERKREKER-GKRERKRKKRKKEEREKKRERNRK 177
E++ R+RE R+E ++ + + +R++E + E+E+ K ER+ +R+++E E++++R R+
Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302
Query: 178 E----RKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLR 224
E RK+E ER+E++E ++E ++ERR+++E +++++ R+ + + + LR
Sbjct: 303 EQQLRRKQEEERREQQEERRE-QQERREQQEERREQQLRREQEERREQQLR 352
Score = 100 bits (249), Expect = 1e-21
Identities = 56/202 (27%), Positives = 127/202 (62%), Gaps = 15/202 (7%)
Query: 29 CTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKE 88
C +RE + R++R+++ RE E++ R+ ++ ++ +++ R +ERERK E E+Q ++
Sbjct: 1401 CQEREQQL---RQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQ 1457
Query: 89 RREKERRKRKKEKKKRERKQRGRRERKKK--KERKERERENKQRRERKRKKRRKKKRRKE 146
R ++ R+ ++ ++RE +Q R+ER +K +E ++ R+ + R+ R+++ R ++ RK
Sbjct: 1458 ERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKF 1517
Query: 147 RKREKERGKRERKRK--------KRKKEEREKKRERNRKERKKERERKERRERKKERKKE 198
+ E++ +++R+RK +R++ ++++++R+RK R++E+ R+ER E++ R +
Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR--Q 1575
Query: 199 RRKKKERKKDRKTDRQTDSQVF 220
R +K R +++K RQ + F
Sbjct: 1576 ERDRKFRLEEQKVRRQEQERKF 1597
Score = 100 bits (248), Expect = 2e-21
Identities = 56/196 (28%), Positives = 128/196 (65%), Gaps = 8/196 (4%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKR-KKRERGKERER-KRKEREKQRKE 88
+RE K+E+ ER + +RE+ER+++R K+E+++R ++R + +E ER +++ER +QR +
Sbjct: 562 RREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLK 621
Query: 89 RREKERRKR----KKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR 144
R E E +R K E+++ R+Q+ RRE+++++E++ + E ++R E++ K+ +++RR
Sbjct: 622 REEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERR 681
Query: 145 KERKREKERGK-RERKRKKRKKEEREKKRERNRKERK-KERERKERRERKKERKKERRKK 202
++ E+E+ + RER + + K + + + E + ++ K R RK+ +R+++ ++E+R++
Sbjct: 682 EQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRR 741
Query: 203 KERKKDRKTDRQTDSQ 218
+E + + + + Q
Sbjct: 742 RESELQWQEEERAHRQ 757
Score = 100 bits (248), Expect = 2e-21
Identities = 55/186 (29%), Positives = 121/186 (65%), Gaps = 8/186 (4%)
Query: 31 QRESERKKERREREKRKREREK----ERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
+R ER+++ RE E+ ++E E+ ER+ R ++ +++ +K E ++ E + E ++
Sbjct: 1041 RRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEK 1100
Query: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
+ R+E+ER+ R++E+ ++E +Q R ER+K++ R+E ER+ ++ E ++++ + + E
Sbjct: 1101 RRRQERERQCREEEELQQEEEQLLREEREKRR-RQELERQYREEEEVQQEEEQLLREEPE 1159
Query: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
++R +E ++ R+ ++ ++EE + RE K R++ERER+ R E + +R+K RK++ R
Sbjct: 1160 KRRRQELERQYREEEELQQEEEQLLREEQEK-RRQERERQYREEEELQRQK--RKQRYRD 1216
Query: 207 KDRKTD 212
+D+++D
Sbjct: 1217 EDQRSD 1222
Score = 100 bits (248), Expect = 2e-21
Identities = 72/223 (32%), Positives = 140/223 (62%), Gaps = 20/223 (8%)
Query: 23 SHISKPCTQRESERKKERREREKRKRERE---KERKRERGKKEKKKRKKRE---RGKERE 76
S K + E E K+ R+E +++ RE E +ER+ + +++++ RK RE R +E+
Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG 1373
Query: 77 RKRKEREKQRKERREKERRKRKKEKKKR--ERKQRGRRERKKKKERKERERENKQRRERK 134
RK E E+QR R+E+ER+ K+E++ R ER+Q+ R++R +K R+E ++ ++Q R+RK
Sbjct: 1374 RKFLE-EEQRLRRQERERKFLKEEQQLRCQEREQQLRQDR-DRKFREEEQQLSRQERDRK 1431
Query: 135 RKKRRKKKRRKERKR----EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRE 190
++ ++ RR+ER+R E+++ ++ER RK R++E+ ++RE + R +ER+RK E
Sbjct: 1432 FREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHR-QERDRKFLEE 1490
Query: 191 RKKERKKERRKK--KERKKDRKTDR---QTDSQVFRPLRESAF 228
++ R++ER +K ++ + ++ +R + + Q+ R R+ F
Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKF 1533
Score = 99.8 bits (247), Expect = 2e-21
Identities = 57/212 (26%), Positives = 138/212 (65%), Gaps = 19/212 (8%)
Query: 33 ESERKKERREREKRKREREKERKRE-RGKKEKKKRKKRERGKERE-RKRKEREKQRKERR 90
E ++++E+ RE+R++ R +ER+R+ R ++E ++ +++ G+ERE R+R+E E+Q ++
Sbjct: 1025 ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEE 1084
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
E ++ + + +++ E+++R RER+ ++E + ++ E + RE + K+RR++ R+ R+ E
Sbjct: 1085 ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEE 1144
Query: 151 K--------------ERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERK 196
+ +R ++E +R+ R++EE +++ E+ +E +++R ++ R+ ++E +
Sbjct: 1145 EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEE 1204
Query: 197 KERRKKKERKKDRKTDRQTDSQ-VFRPLRESA 227
+R+K+K+R +D D+++D + + P +E+A
Sbjct: 1205 LQRQKRKQRYRDE--DQRSDLKWQWEPEKENA 1234
Score = 99.4 bits (246), Expect = 3e-21
Identities = 54/185 (29%), Positives = 123/185 (66%), Gaps = 7/185 (3%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKE-- 88
++E +RK E + R++ERE++ + +R +K +++ + + G+E++ +R+ER+++ +E
Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEE 1697
Query: 89 ---RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
RR++ RK +E+++ R++ R+ R++++ R+E E+E +R+ER RK +++ R
Sbjct: 1698 QQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRP 1757
Query: 146 ERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKER 205
ER+ ++ R ++ER RK R++E+ ++RE ++ R +E +RK R E + +++E ++ + +
Sbjct: 1758 EREEQQLR-RQERDRKFREEEQLRQERE-EQQLRSQESDRKFREEEQLRQEREEQQLRPQ 1815
Query: 206 KKDRK 210
++D K
Sbjct: 1816 QRDGK 1820
Score = 99.0 bits (245), Expect = 4e-21
Identities = 65/213 (30%), Positives = 131/213 (61%), Gaps = 16/213 (7%)
Query: 32 RESERKKERREREKRKREREKERKRERGKK---EKKKRKKRERGK----ERERKRKEREK 84
RE E++ R+ERE++ E E++ ++ER +K E++ ++RE + ER+RK E E+
Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQ 1492
Query: 85 Q--RKER----REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138
Q R+ER RE+E R ++ E+K E +Q+ R+++++K +E ++ +Q R ++R++
Sbjct: 1493 QLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQD 1552
Query: 139 RKKKRRKERKREKERGKRERKRKKRKKEER--EKKRERNRKERK-KERERKERRERKKER 195
R +K R+E + +ER +++ R++R ++ R E+K R +ERK E E++ RR+ +++
Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612
Query: 196 KKERRKKKERKKDRKTDRQTDSQVFRPLRESAF 228
++ R +K R+ ++ + + Q+ R R+ F
Sbjct: 1613 LRQERDRKFREDEQLLQEREEQQLHRQERDRKF 1645
Score = 99.0 bits (245), Expect = 4e-21
Identities = 59/216 (27%), Positives = 129/216 (59%), Gaps = 20/216 (9%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
R ER ++ RE+E R +E E++ E + +++R+++ +E++ +R+ER +QR++ R+
Sbjct: 1495 RRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD 1554
Query: 92 KERRKRKKEKKKRERKQRGRRERKKK------------KERKERERENKQRRERKRKKRR 139
++ R+ ++ +++RE +Q R+ER +K +ERK E E + RR+ +++ R
Sbjct: 1555 RKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLR 1614
Query: 140 KKKRRKER-------KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERK 192
+++ RK R +RE+++ R+ + +K +EE + +R+ ++ + +R+RK R E +
Sbjct: 1615 QERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQ 1674
Query: 193 KERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAF 228
++ E ++ + +++DRK R+ + Q+ R RE F
Sbjct: 1675 LLQEGEEQQLRRQERDRKF-REEEQQLRRQERERKF 1709
Score = 98.6 bits (244), Expect = 5e-21
Identities = 54/208 (25%), Positives = 128/208 (61%), Gaps = 9/208 (4%)
Query: 29 CTQRESERKKERREREKRKREREKERKRERGKKEKKKRKK-RERGKERER-----KRKER 82
C RE+E+ ++ + + R R+ +++ + G+++++ R++ R R ++R+R ++ ER
Sbjct: 1242 CKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLER 1301
Query: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK 142
E+Q++ +R + + +K+ + ER+++ RR+ +K R+E + ++ + R++ R +K
Sbjct: 1302 EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRK 1361
Query: 143 RRKERKREKERGKR--ERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERR 200
R+E R +E+G++ E +++ R++E K + ++ R +ERE++ R++R ++ ++E +
Sbjct: 1362 FREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ 1421
Query: 201 KKKERKKDRKTDRQTDSQVFRPLRESAF 228
+ +++DRK R+ + QV R RE F
Sbjct: 1422 QLSRQERDRKF-REEEQQVRRQERERKF 1448
Score = 98.6 bits (244), Expect = 5e-21
Identities = 60/226 (26%), Positives = 147/226 (65%), Gaps = 27/226 (11%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK-----Q 85
+++ +RK + E++ R++ER ++R+++R +K +++ + R+ +E++ R+ER++ +
Sbjct: 1526 RQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEE 1585
Query: 86 RKERREKERRK--------RKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK- 136
+K RR+++ RK R++E +++ R++R R+ R+ ++ +ERE + R+ER RK
Sbjct: 1586 QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKF 1645
Query: 137 -----KRRKKKRRKERKREKERGKRERKRKKRKKEERE-KKRERNRKERKKERE-RKERR 189
+ R+++R ++ + +++R RE ++ ++ EE++ +++ER+RK R++E++ R++ R
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
Query: 190 ERK--KERKKERRKKKERK--KDRKTDRQTDSQVFRPLRESAFNRV 231
ERK +E ++ RR++ ERK ++ + ++T+ + R R+ + ++
Sbjct: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLR--RQERYRKI 1749
Score = 98.2 bits (243), Expect = 7e-21
Identities = 61/210 (29%), Positives = 130/210 (61%), Gaps = 12/210 (5%)
Query: 29 CTQRESERKKERREREKRKRE-REKERKRERGKKEKKKRKKRER----GKERERKRKERE 83
C +ES + R+E ++R+ E R+++ + E G++ ++KR+++ER G+E+ K++ E
Sbjct: 103 CDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLE 162
Query: 84 KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKR 143
++ ++RR++E ++++E ++RE + R E ++ + K E E E+ R++ + R
Sbjct: 163 QRDRQRRDEELWRQRQEWQEREER---RAEEEQLQSCKGHETEEFPDEEQLRRRELLELR 219
Query: 144 RKERKREKERGKRERKRKKRKKEEREKKRERN---RKERKKERERKERRERKKERKKERR 200
RK R+ EK++ +RER+ + ++EE ++ R+R RKE +K +E + +R+R+ + ++E+
Sbjct: 220 RKGRE-EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
Query: 201 KKKERKKDRKTDRQTDSQVFRPLRESAFNR 230
+K ER++ R+ ++ + Q R RE R
Sbjct: 279 RKLERQELRRERQEEEQQQQRLRREQQLRR 308
Score = 98.2 bits (243), Expect = 7e-21
Identities = 47/193 (24%), Positives = 116/193 (60%), Gaps = 11/193 (5%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
+R+ K+E R++R + ++ER +R K+E+ +R ++E +E+ KR+E E++R+++
Sbjct: 574 RRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL 633
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
K + ++ +++ R+Q+ RRE++ K+E +E E + +RE + ++R ++ +E+++
Sbjct: 634 LKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQA 693
Query: 151 KERGK-----------RERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER 199
+ER K E ++ K R +K+E R+ +++E +R+ R + +++ER
Sbjct: 694 RERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEER 753
Query: 200 RKKKERKKDRKTD 212
+++++++++ D
Sbjct: 754 AHRQQQEEEQRRD 766
Score = 97.4 bits (241), Expect = 1e-20
Identities = 66/210 (31%), Positives = 130/210 (61%), Gaps = 16/210 (7%)
Query: 31 QRESERKKERREREKRKRER-----EKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
+ E + +ER E++ ++ER E+E++ R ++++K R++ R +E ERK E E+Q
Sbjct: 1464 REEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQ 1523
Query: 86 --RKERREK----ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR 139
R++R+ K E++ R++E+ ++ R+ R R+ R++++ R+ERE + R+ER RK R
Sbjct: 1524 LHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRL 1583
Query: 140 KKKRRKERKREKERGKRERKRKKRKKE-EREKKRERNRKERKKERERKERRERKKERKKE 198
++ +K R++E+ER E +++ R++E +++ ++ER+RK R+ E+ +ER E++ R++
Sbjct: 1584 EE--QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQER 1641
Query: 199 RRKKKERKKDRKTDRQTDSQVFRPLRESAF 228
RK E + + RQ Q R R+ F
Sbjct: 1642 DRKFLEEEPQLR--RQEREQQLRHDRDRKF 1669
Score = 97.4 bits (241), Expect = 1e-20
Identities = 62/214 (28%), Positives = 136/214 (63%), Gaps = 20/214 (9%)
Query: 31 QRESERKKERREREKRKREREKER--KRERGKK-----EKKKRKKRERG-KERERKRKER 82
QR +R ++ RE E+ ++ERE+++ ++ER +K +K +R+++ER E E++ + +
Sbjct: 1548 QRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ 1607
Query: 83 EKQRKERREKERRKRKKEK--KKRERKQRGRRERKKK-----KERKERERENKQRRERKR 135
E Q++ R+E++R+ R+ E+ ++RE +Q R+ER +K + + +ERE + R +R R
Sbjct: 1608 EGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDR 1667
Query: 136 KKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRK----ERKKERERKERRER 191
K R +++ +E + ++ R ++ER RK R++E++ +++ER RK E++ R+ ER+ R
Sbjct: 1668 KFREEEQLLQEGEEQQLR-RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFR 1726
Query: 192 KKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
++E+ ++ ++++ ++ + + + + RP RE
Sbjct: 1727 EEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760
Score = 96.7 bits (239), Expect = 2e-20
Identities = 60/196 (30%), Positives = 130/196 (66%), Gaps = 16/196 (8%)
Query: 31 QRESERKKERREREKRKRE-----REKERKRERGKKEKKKRKKRERG-KERERKRKEREK 84
++E ERK + E++ R++E RE+E+ R+ ++E+ +R++R R E E+ R ERE+
Sbjct: 1702 RQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREE 1761
Query: 85 QRKERREKERRKRKKEKKKRERKQRGRRERK-----KKKERKERERENKQRRERKRK-KR 138
Q+ R+E++R+ R++E+ ++ER+++ R ++ +++E+ +ERE +Q R ++R K
Sbjct: 1762 QQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKY 1821
Query: 139 RKKKRRKERKREKERGKRERKRKKRKKEE--REKKRERNRKERKKERERKERRERKKERK 196
R ++ + + + +++R ++ER R+ R +E+ ++K R +E +E E+K R+ER+++ +
Sbjct: 1822 RWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLR 1881
Query: 197 KE--RRKKKERKKDRK 210
+E RR++KE ++ R+
Sbjct: 1882 EEHIRRQQKEEQRHRQ 1897
Score = 96.3 bits (238), Expect = 3e-20
Identities = 54/190 (28%), Positives = 116/190 (61%), Gaps = 13/190 (6%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKE-KKKRKKRERGKERERKRKEREKQR--- 86
Q++ R+++ R ++ KRE E+ER +R K+E +++R+++E +E + + +ER K R
Sbjct: 644 QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPK 703
Query: 87 -KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
+ + E E R+ + R RKQ G+R R++++E++ R Q +E +R R++++ +
Sbjct: 704 WQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763
Query: 146 ERK-----REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERR 200
R + +E+ +R R+R + RE +R R+ R +ER+++E+R +E +KE+R
Sbjct: 764 RRDFTWQWQAEEKSERGRQRLSARPPLRE---QRERQLRAEERQQREQRFLPEEEEKEQR 820
Query: 201 KKKERKKDRK 210
+++ R+++++
Sbjct: 821 RRQRREREKE 830
Score = 96.3 bits (238), Expect = 3e-20
Identities = 52/201 (25%), Positives = 129/201 (64%), Gaps = 8/201 (3%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
R E+K R+E+E++ E E++ +R+ G+++ ++ + R + +E E+ +ERE+Q+ R+E
Sbjct: 1582 RLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDR-KFREDEQLLQEREEQQLHRQE 1640
Query: 92 KERR-------KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR 144
++R+ R++E++++ R R R+ R++++ +E E + +R+ER RK R ++++
Sbjct: 1641 RDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQL 1700
Query: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE 204
+ ++RE++ + E++ ++++ E + ++ E+ R+E ++E+ R++ R RK +++ R ++E
Sbjct: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760
Query: 205 RKKDRKTDRQTDSQVFRPLRE 225
++ R+ +R + LR+
Sbjct: 1761 EQQLRRQERDRKFREEEQLRQ 1781
Score = 95.9 bits (237), Expect = 3e-20
Identities = 67/222 (30%), Positives = 134/222 (60%), Gaps = 30/222 (13%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERK---------RKER 82
+E E + RR+ RK E+ R +E+G+K ++ ++R R +ERERK +ER
Sbjct: 1346 QEREEQPLRRQERDRKFREEELRHQEQGRKFLEE-EQRLRRQERERKFLKEEQQLRCQER 1404
Query: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRE----RKKKKERKERERENKQRRERKRKKR 138
E+Q ++ R+++ R+ +++ ++ER ++ R E R++++ERK E E + R+ER RK R
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR 1464
Query: 139 RKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK-----KERERK------- 186
+++ +ER+ E++ ++ER RK ++E++ +++ER+RK R+ +E ERK
Sbjct: 1465 EEEQLLQERE-EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQ 1523
Query: 187 ---ERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
++R+RK +++++ +++ER + R+ DR + LR+
Sbjct: 1524 LHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQ 1565
Score = 95.5 bits (236), Expect = 4e-20
Identities = 70/248 (28%), Positives = 138/248 (55%), Gaps = 41/248 (16%)
Query: 27 KPCTQRESERKKERREREKRKRE-----REKERKRERGKKEKKKRKKRERGKERERKRKE 81
+P +R ER+++ RE E+ ++E RE+ KR R + E++ R++ E +E E+ +E
Sbjct: 1097 EPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLRE 1156
Query: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141
E +++ R+E ER+ R++E+ ++E +Q R E++K+ R+ERER+ ++ E +R+KR+++
Sbjct: 1157 -EPEKRRRQELERQYREEEELQQEEEQLLREEQEKR--RQERERQYREEEELQRQKRKQR 1213
Query: 142 KRRKERKR--------EKERGKRERKRKKRKKEEREKKR--------------------E 173
R ++++ EKE R+ K + +E + ++ E
Sbjct: 1214 YRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGE 1273
Query: 174 RNRKERKKERERKERRER--KKERKKERRKKKE-RKKDRKTDRQTDSQVFRPLRESAFNR 230
+ ++R++ER R ++R+R +E + ER ++KE +++DRK+ Q + Q+ R RE R
Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKS--QEEKQLLREEREEKRRR 1331
Query: 231 VTVTGVFR 238
FR
Sbjct: 1332 QETDRKFR 1339
Score = 95.1 bits (235), Expect = 6e-20
Identities = 60/211 (28%), Positives = 135/211 (63%), Gaps = 15/211 (7%)
Query: 31 QRESERKKERREREKRKR-EREKERKRERGKK--EKKKRKKRERGK-----ERERKRKER 82
Q E++ R+ER+++ R E +K R++E+ +K E +++ +R+ G+ ER+RK +E
Sbjct: 1565 QEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRED 1624
Query: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRERKKK-----KERKERERENKQRRERKRKK 137
E+ +ER E++ ++++++K E + + RR+ +++ ++RK RE E + +++
Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQL 1684
Query: 138 RRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKK 197
RR+++ RK R+ E++ ++ER+RK ++E++ +++E RK R++E+ R+E E+++ R++
Sbjct: 1685 RRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQE-TEQEQLRRQ 1743
Query: 198 ERRKKKERKKDRKTDRQTDSQVFRPLRESAF 228
ER +K ++ + +R+ + Q+ R R+ F
Sbjct: 1744 ERYRKILEEEQLRPERE-EQQLRRQERDRKF 1773
Score = 94.7 bits (234), Expect = 8e-20
Identities = 66/239 (27%), Positives = 132/239 (55%), Gaps = 43/239 (17%)
Query: 32 RESERKKERREREKRKREREKERKRE----RGKKEKKKRKKRERG--------------- 72
RE K+ R+E E++ RE E+ ++ E R + EK++R++ ER
Sbjct: 1125 REEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL 1184
Query: 73 -KERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERE------- 124
+E+E++R+ERE+Q +E E +R+KRK+ + +++ + + + +KE R+
Sbjct: 1185 REEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKG 1244
Query: 125 RENKQRRERKRKKRRKKK----------RRKERKREKERGK---RERKRKKRKKEEREKK 171
REN+Q R+ + + R ++ ++ER RE+ER + R+R + ++ ERE++
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304
Query: 172 RERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNR 230
+E R++RK + E++ RE ER+++RR+++ +K R+ ++ + +PLR +R
Sbjct: 1305 KEAKRRDRKSQEEKQLLRE---EREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDR 1360
Score = 94.4 bits (233), Expect = 1e-19
Identities = 56/196 (28%), Positives = 123/196 (62%), Gaps = 22/196 (11%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
R ER ++ RE E++ R +E+ERK + +++ ++++ + +E E+ R+E E+++ R+E
Sbjct: 1685 RRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQE 1744
Query: 92 KERR-------KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR 144
+ R+ + ++E+++ R++R R+ R++++ R+ERE + + +E RK R +++ R
Sbjct: 1745 RYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLR 1804
Query: 145 KERKREKERGKRERKRKKRKKEER---EKKRERNRKERKK-----------ERERKERRE 190
+ER+ ++ R ++R K R +EE+ E++ +R R+ER + E+ R+E +E
Sbjct: 1805 QEREEQQLR-PQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE 1863
Query: 191 RKKERKKERRKKKERK 206
+E +++RR+++ERK
Sbjct: 1864 LWQEEEQKRRQERERK 1879
Score = 94.0 bits (232), Expect = 1e-19
Identities = 58/206 (28%), Positives = 132/206 (64%), Gaps = 17/206 (8%)
Query: 31 QRESERKKERREREKRKREREKER--KRERGKK---EKKKRKKRERGKE----RERKRKE 81
Q ER ++ RE E+ +ERE+++ ++ER +K E+ + +++ER ++ R+RK +E
Sbjct: 1612 QLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFRE 1671
Query: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK--RKKRR 139
E+ +E E++ R++++++K RE +Q+ RR+ +++K +E ++ +Q ERK +++
Sbjct: 1672 EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQL 1731
Query: 140 KKKRRKERKREKERGKR---ERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERK 196
+++ +E+ R +ER ++ E + + ++E++ +++ER+RK R++E+ R+ER E++ +
Sbjct: 1732 RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Query: 197 KERRKKKERKKDRKTDRQTDSQVFRP 222
+ RK +E ++ R ++ + Q RP
Sbjct: 1792 ESDRKFREEEQLR---QEREEQQLRP 1814
Score = 92.8 bits (229), Expect = 3e-19
Identities = 56/224 (25%), Positives = 127/224 (56%), Gaps = 31/224 (13%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
+RE K+E E E+R++ + E + ER ++++ R++++ +E+ KR+E E++ ++R
Sbjct: 615 RREQRLKREEPEEERRQQLLKSEEQEER--RQQQLRREQQERREQRLKREEEEERLEQRL 672
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKK---------------KERKERERENKQRRERKR 135
++E + ++E++ E +Q RER K ++ K R KQ +R+R
Sbjct: 673 KREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRR 732
Query: 136 KKRRKKKRRKERK---REKERGKRERKRKKRKKE-----EREKKRERNRKE------RKK 181
+++ +K+RR+E + +E+ER R+++ ++++++ + E+K ER R+ ++
Sbjct: 733 QEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLRE 792
Query: 182 ERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
+RER+ R E +++R++ ++E K+ R+ R+ + + L E
Sbjct: 793 QRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEE 836
Score = 92.8 bits (229), Expect = 3e-19
Identities = 58/240 (24%), Positives = 139/240 (57%), Gaps = 12/240 (5%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
+ E ++++E+ E+R+ R +E +R+ K+E+ ++++ + +E KR+ +E++R+ R
Sbjct: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE 1112
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKK-KERKERERENKQRRERKRKKRRKKKRRKERKR 149
E+E ++ +++ + ER++R R+E +++ +E +E ++E +Q + +KRR+++ ++ +
Sbjct: 1113 EEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172
Query: 150 EKERGKRERKRKKRKKEEREKKRERN-RKERKKERERKERRERKKERKKERRKKKERKKD 208
E+E + E + + ++E+R ++RER R+E + +R+++++R R ++++ + + + E +K+
Sbjct: 1173 EEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKE 1232
Query: 209 RKTDRQTDSQVFRPLRESAFNRVTVTGVFRYRIFHTGLDHFPIKTNILLSRHEVNDGEIE 268
D++V+ RE+ R R R L H LL + D E E
Sbjct: 1233 NAV---RDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQH-------LLGEQQERDREQE 1282
Score = 92.4 bits (228), Expect = 4e-19
Identities = 68/259 (26%), Positives = 139/259 (53%), Gaps = 47/259 (18%)
Query: 16 ELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKE--------KKKRK 67
ELQ + + +R ER+++ RE E+ +R++ K+R R+ ++ +K+
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
Query: 68 KRE-----RGKERERKRK-----------------------EREKQRKERREKERRKRKK 99
R+ +G+E E+ R+ ER+++++ RR ++R +
Sbjct: 1235 VRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFP 1294
Query: 100 EKKKRER---KQRGRRERKKKKERK--ERERENKQRRERKRKKRRKKKRRKERKREKERG 154
E+++ ER K+ RR+RK ++E++ ERE K+RR+ +K R++++ + + E+
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR 1354
Query: 155 KRERKRKKRKKEEREKKR-----ERNRKERKKERERKERRERKKERKKERRKKKERKKDR 209
++ER RK R++E R +++ E ++ R++ERERK +E ++ R +ER ++ + +DR
Sbjct: 1355 RQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR 1414
Query: 210 KTDRQTDSQVFRPLRESAF 228
K R+ + Q+ R R+ F
Sbjct: 1415 KF-REEEQQLSRQERDRKF 1432
Score = 92.0 bits (227), Expect = 5e-19
Identities = 55/191 (28%), Positives = 123/191 (64%), Gaps = 10/191 (5%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERG-KERERKRKEREKQRKER 89
Q E++ R+ER+++ E E + +R+ ++E++ R R+R +E E+ +E E+Q+ R
Sbjct: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQ--EREQQLRHDRDRKFREEEQLLQEGEEQQLRR 1686
Query: 90 REKERRKRKKE----KKKRERK--QRGRRERKKKKERKERERENKQRRERKRKKRRKKKR 143
+E++R+ R++E +++RERK Q ++ R+++ ERK RE E ++ + + RR+++
Sbjct: 1687 QERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERY 1746
Query: 144 RKERKREKERGKRERKRKKRKKEERE-KKRERNRKERKKERERKERRERKKERKKERRKK 202
RK + E+ R +RE ++ +R++ +R+ ++ E+ R+ER++++ R + +RK +++ R++
Sbjct: 1747 RKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQE 1806
Query: 203 KERKKDRKTDR 213
+E ++ R R
Sbjct: 1807 REEQQLRPQQR 1817
Score = 91.7 bits (226), Expect = 6e-19
Identities = 68/246 (27%), Positives = 135/246 (54%), Gaps = 51/246 (20%)
Query: 31 QRESERKKER--REREKRKREREKERKRERGKKEKKK--RKKRERGKERER----KRKER 82
+RE ER+++R RE+E+R +R K + ER ++E+++ R KRE +E R K +E+
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639
Query: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKER------ERENKQRRERKRK 136
E++R+++ +E+++R++++ KRE ++ +R K++ +ER E E +Q RER +
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
Query: 137 K--------------------RRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNR 176
+ R +K+ +R+R+++ E KR++R+ E + ++ ER
Sbjct: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ----EEKRRRRESELQWQEEERAH 755
Query: 177 KERKKERERKE-----RRERKKERKKER-------RKKKERKKDRKTDRQTDSQVFRPLR 224
+++++E +R++ + E K ER ++R R+++ER+ R +RQ Q F P
Sbjct: 756 RQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQL-RAEERQQREQRFLPEE 814
Query: 225 ESAFNR 230
E R
Sbjct: 815 EEKEQR 820
Score = 91.7 bits (226), Expect = 6e-19
Identities = 49/210 (23%), Positives = 126/210 (60%), Gaps = 15/210 (7%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
++E ERK E++ R++E +++ ++ER +K ++ + + +E++ R+ER+++ E
Sbjct: 1590 RQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEE 1649
Query: 91 EKERRKRKKEKKKRERKQRGRRE------------RKKKKERKERERENKQRRERKRKKR 138
+ RR+ ++++ + +R ++ R E R+++++RK RE E + RR+ + +K
Sbjct: 1650 PQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKF 1709
Query: 139 RKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRE---RKKER 195
+++++ R+ + + + E + ++ ++E+ +++ER RK ++E+ R ER E R++ER
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER 1769
Query: 196 KKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
++ R++++ +++R+ + + R RE
Sbjct: 1770 DRKFREEEQLRQEREEQQLRSQESDRKFRE 1799
Score = 91.7 bits (226), Expect = 6e-19
Identities = 50/206 (24%), Positives = 129/206 (62%), Gaps = 14/206 (6%)
Query: 27 KPCTQRESERKKERREREKRKREREK------ERKRERGKKEKKKRKKRERGKERERKRK 80
+P +R+ ++ R +R+++ RE E+ E++ R ++++K R++ ++ + +ER+RK
Sbjct: 1649 EPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERK 1708
Query: 81 E-REKQRKERREKERRKRKKEKKKRE-------RKQRGRRERKKKKERKERERENKQRRE 132
+E+Q+ R+E ER+ R++E+ ++E R++R R+ ++++ R ERE + +R+E
Sbjct: 1709 FLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQE 1768
Query: 133 RKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERK 192
R RK R +++ R+ER+ ++ R + ++ + +++ R+++ E+ + ++++ + + E+
Sbjct: 1769 RDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQL 1828
Query: 193 KERKKERRKKKERKKDRKTDRQTDSQ 218
+ ++E+R ++ER + + + Q +Q
Sbjct: 1829 QLEEQEQRLRQERDRQYRAEEQFATQ 1854
Score = 90.9 bits (224), Expect = 1e-18
Identities = 55/229 (24%), Positives = 130/229 (56%), Gaps = 38/229 (16%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKE-----RERKRKEREKQR 86
R+ E ++ R+E+E+++R RE E + + ++ +++++ E+ ++ + ++ ER +QR
Sbjct: 724 RKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR 783
Query: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR-------KKRR 139
R R +R+++ + ER+QR E++ E +E+E+ +QRRER++ +++
Sbjct: 784 LSARPPLREQRERQLRAEERQQR---EQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL 840
Query: 140 KKKRRKERKREKERGKRERKRKKRKKEER-----------EKKRERN------------R 176
+++ R ++ +E+E G +E + ++R +E+R E+KR R+ R
Sbjct: 841 QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR 900
Query: 177 KERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
KE++ +E +E +R++ K+ R++++ + ++ + +Q + Q+ R RE
Sbjct: 901 KEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE 949
Score = 90.1 bits (222), Expect = 2e-18
Identities = 49/198 (24%), Positives = 125/198 (63%), Gaps = 3/198 (1%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
++E+E+++ RR+ RK E++ + ER +++ +++++ + +E E+ R+ERE+Q+ +
Sbjct: 1732 RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Query: 91 EKERRKRKKEKKKRERKQRGRR--ERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
E +R+ R++E+ ++ER+++ R +R K +E + + +++ +R R++R ++ R +E+
Sbjct: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQF 1851
Query: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
+E+ +RE +++ ++EE+++++ER RK R++ R+++ E++ + E + ++ +
Sbjct: 1852 ATQEKSRRE-EQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHG 1910
Query: 209 RKTDRQTDSQVFRPLRES 226
R + T P+R S
Sbjct: 1911 RLLEPGTHQFASVPVRSS 1928
Score = 89.0 bits (219), Expect = 4e-18
Identities = 57/201 (28%), Positives = 125/201 (62%), Gaps = 12/201 (5%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKK---EKKKRKKRERGKER--ERKRKEREKQ 85
++E ERK E+ +++ E+E+ R++ER +K E++ R +RE + R ER RK RE++
Sbjct: 1718 RQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEE 1777
Query: 86 --RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR--RERKRKKRRKK 141
R+ER E++ R ++ ++K RE +Q R+ +++++ + ++R+ K R E+ + + +++
Sbjct: 1778 QLRQEREEQQLRSQESDRKFREEEQ--LRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQ 1835
Query: 142 KRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
+ R+ER R+ ++ ++K ++EE+E +E +K R++ERERK R E + ++KE ++
Sbjct: 1836 RLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQK-RRQERERKLREEHIRRQQKEEQR 1894
Query: 202 KKERKKDRKTDRQTDSQVFRP 222
++ + + + + ++ P
Sbjct: 1895 HRQVGEIKSQEGKGHGRLLEP 1915
Score = 85.5 bits (210), Expect = 5e-17
Identities = 50/218 (22%), Positives = 129/218 (59%), Gaps = 20/218 (9%)
Query: 28 PCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK 87
P Q + E + + R+ + R R++E +R R ++E+K+R++ + +E +R R++Q +
Sbjct: 702 PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761
Query: 88 ERRE--------KERRKRKKEKKKRERKQRGRRERK-KKKERKERER----ENKQRRERK 134
E+R +E+ +R +++ R +RER+ + +ER++RE+ E +++ +R+
Sbjct: 762 EQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRR 821
Query: 135 RKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
R++R ++K + + E++ +RER ++ +++E+ ++ + R+ +++ R++K R + ++E
Sbjct: 822 RQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEE 881
Query: 195 RKKERRK-------KKERKKDRKTDRQTDSQVFRPLRE 225
RK+ R +++ +K+++ ++ + ++ R RE
Sbjct: 882 RKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREERE 919
Score = 61.2 bits (147), Expect = 9e-10
Identities = 40/161 (24%), Positives = 94/161 (58%), Gaps = 10/161 (6%)
Query: 55 KRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRER 114
+ +R + + K+ ++R +E +++R E ++ E +RR++K+++++RE + E+
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEG--EEQ 154
Query: 115 KKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRER 174
+K+ER E +R+ ++R E ++R++ + R+ER+ E+E + + K + E E+
Sbjct: 155 SEKQERLE-QRDRQRRDEELWRQRQEWQEREERRAEEE----QLQSCKGHETEEFPDEEQ 209
Query: 175 NRKERKKERERKERRERKKERKKERRK---KKERKKDRKTD 212
R+ E RK R E++++R++ + + ++E K+ RK +
Sbjct: 210 LRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRE 250
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 118 bits (295), Expect = 6e-27
Identities = 60/190 (31%), Positives = 110/190 (57%), Gaps = 5/190 (2%)
Query: 32 RESERKKERREREKRKREREKERK-RERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
R+ KKE++ERE+R++ERE+ER+ RER ++ +++ +++ER ++RER+++ R + R R
Sbjct: 243 RDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSR 302
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
+RR + KR R + RR R + + R+ R + +R+ R R + R++ + ++RK
Sbjct: 303 TSDRRCSRSRDHKRSRSRERRRSRSRDR-RRSRSHDRSERKHRSRSRDRRRSKSRDRKSY 361
Query: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE---RKK 207
K R K + + RK +E+EK+ ++K K R+++ E KE K E +
Sbjct: 362 KHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSE 421
Query: 208 DRKTDRQTDS 217
D K++ T S
Sbjct: 422 DIKSEGDTQS 431
Score = 112 bits (280), Expect = 4e-25
Identities = 57/192 (29%), Positives = 108/192 (56%), Gaps = 3/192 (1%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
T E + K +R E + ER K+ K+ER ++EK++ ++RE +ER+R+R+E E++++
Sbjct: 226 TVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREE-RERKRRREEEEREKERA 284
Query: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
R++ERRKR + + + + RR + + ++ R RE ++ R R R++ R R + + R
Sbjct: 285 RDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHR 344
Query: 150 EKERGKRERKRKKRKK-EEREKKRERNRKERKKERERKERRERKKERKK-ERRKKKERKK 207
+ R +R K + RK + R K R+R + + KE+E++ ++K K R K+ E
Sbjct: 345 SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTN 404
Query: 208 DRKTDRQTDSQV 219
+ T ++V
Sbjct: 405 TESKESDTKNEV 416
Score = 103 bits (256), Expect = 2e-22
Identities = 48/167 (28%), Positives = 99/167 (59%), Gaps = 1/167 (0%)
Query: 52 KERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER-REKERRKRKKEKKKRERKQRG 110
K E +K +K+ ++ +R + +++++ERE++ KER RE+E R+RK+ +++ ER++
Sbjct: 224 KATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKER 283
Query: 111 RRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREK 170
R+R+++K + R R + + +R+ + R KR + R+R + R + R+ + + ER+
Sbjct: 284 ARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKH 343
Query: 171 KRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDS 217
+ + R K R+RK + R K R +E+ +K + K+ R +D + S
Sbjct: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSS 390
Score = 100 bits (249), Expect = 1e-21
Identities = 55/156 (35%), Positives = 93/156 (59%), Gaps = 5/156 (3%)
Query: 70 ERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ 129
E KE+ RKR E E R ER +KE+++R E++++ER +R R ER++K+ R+E ERE ++
Sbjct: 228 EELKEKLRKRTE-EPDRDERLKKEKQER--EEREKER-EREREERERKRRREEEEREKER 283
Query: 130 RRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERR 189
R+R+R+KR + + R + R R R K+ + ER + R R+R+ R + +R ER+
Sbjct: 284 ARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR-RSRSHDRSERK 342
Query: 190 ERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
R + R + R K ++RK + + D + R +E
Sbjct: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKE 378
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 118 bits (295), Expect = 6e-27
Identities = 60/190 (31%), Positives = 110/190 (57%), Gaps = 5/190 (2%)
Query: 32 RESERKKERREREKRKREREKERK-RERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
R+ KKE++ERE+R++ERE+ER+ RER ++ +++ +++ER ++RER+++ R + R R
Sbjct: 243 RDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSR 302
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
+RR + KR R + RR R + + R+ R + +R+ R R + R++ + ++RK
Sbjct: 303 TSDRRCSRSRDHKRSRSRERRRSRSRDR-RRSRSHDRSERKHRSRSRDRRRSKSRDRKSY 361
Query: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE---RKK 207
K R K + + RK +E+EK+ ++K K R+++ E KE K E +
Sbjct: 362 KHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSE 421
Query: 208 DRKTDRQTDS 217
D K++ T S
Sbjct: 422 DIKSEGDTQS 431
Score = 112 bits (280), Expect = 4e-25
Identities = 57/192 (29%), Positives = 108/192 (56%), Gaps = 3/192 (1%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
T E + K +R E + ER K+ K+ER ++EK++ ++RE +ER+R+R+E E++++
Sbjct: 226 TVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREE-RERKRRREEEEREKERA 284
Query: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
R++ERRKR + + + + RR + + ++ R RE ++ R R R++ R R + + R
Sbjct: 285 RDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHR 344
Query: 150 EKERGKRERKRKKRKK-EEREKKRERNRKERKKERERKERRERKKERKK-ERRKKKERKK 207
+ R +R K + RK + R K R+R + + KE+E++ ++K K R K+ E
Sbjct: 345 SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTN 404
Query: 208 DRKTDRQTDSQV 219
+ T ++V
Sbjct: 405 TESKESDTKNEV 416
Score = 103 bits (256), Expect = 2e-22
Identities = 48/167 (28%), Positives = 99/167 (59%), Gaps = 1/167 (0%)
Query: 52 KERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER-REKERRKRKKEKKKRERKQRG 110
K E +K +K+ ++ +R + +++++ERE++ KER RE+E R+RK+ +++ ER++
Sbjct: 224 KATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKER 283
Query: 111 RRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREK 170
R+R+++K + R R + + +R+ + R KR + R+R + R + R+ + + ER+
Sbjct: 284 ARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKH 343
Query: 171 KRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDS 217
+ + R K R+RK + R K R +E+ +K + K+ R +D + S
Sbjct: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSS 390
Score = 100 bits (249), Expect = 1e-21
Identities = 55/156 (35%), Positives = 93/156 (59%), Gaps = 5/156 (3%)
Query: 70 ERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ 129
E KE+ RKR E E R ER +KE+++R E++++ER +R R ER++K+ R+E ERE ++
Sbjct: 228 EELKEKLRKRTE-EPDRDERLKKEKQER--EEREKER-EREREERERKRRREEEEREKER 283
Query: 130 RRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERR 189
R+R+R+KR + + R + R R R K+ + ER + R R+R+ R + +R ER+
Sbjct: 284 ARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR-RSRSHDRSERK 342
Query: 190 ERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
R + R + R K ++RK + + D + R +E
Sbjct: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKE 378
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 111 bits (278), Expect = 6e-25
Identities = 75/268 (27%), Positives = 149/268 (55%), Gaps = 48/268 (17%)
Query: 8 RAAVKLNTELQM-VSCSHISKPCTQRESERKKERREREKRKREREKERKR---------E 57
++ +K NT L+M CS + K + E+ R+KE E+ +R++ E +R+R E
Sbjct: 517 KSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE 576
Query: 58 RGKKEKKKRKKRERGKERERKRKER---------EKQRKERREKERRKRKKEKKKRERKQ 108
R +K + R++ E+ KE ++K+ E+ EK ++ER +E+ K+K KK E +
Sbjct: 577 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 636
Query: 109 RGRRE-----------------------RKKKKERKERER---ENKQRRERKRKKRRKKK 142
R++ +KKK+E +ER R E K+ E++ ++RR+++
Sbjct: 637 ARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE 696
Query: 143 RRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER--- 199
RR++ +RE+ER ++ER+ ++R+ E+E++RE+ R + ++E + +E+ R ++ + +R
Sbjct: 697 RREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELE 756
Query: 200 RKKKERKKDRKTDRQTDSQVFRPLRESA 227
KKK+ ++ R +RQ + + +E+A
Sbjct: 757 EKKKKEEQQRLAERQLQEEQEKKAKEAA 784
Score = 102 bits (254), Expect = 4e-22
Identities = 65/228 (28%), Positives = 132/228 (57%), Gaps = 20/228 (8%)
Query: 11 VKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRE 70
VKL E ++ + Q + E+KK+ ++ + E+ ++ K ER +EK K+K
Sbjct: 570 VKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAA 629
Query: 71 RGKER-ERKRKEREKQRK----ERREKERR------KRKKEKKKRERKQ-------RGRR 112
+ E E +RK+ E+ R+ ++ E+ERR K+K+E+++R RK R
Sbjct: 630 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQRE 689
Query: 113 ERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKR 172
+ ++++ER+E+ER ++RRE++R+++ ++ +ER+RE+ER + ER+ ++R+K R +K
Sbjct: 690 QERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKE 749
Query: 173 ERNRK--ERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
+ R+ E+KK+ E++ ER+ + ++E++ K+ + + D Q
Sbjct: 750 QLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQ 797
Score = 53.9 bits (128), Expect = 1e-07
Identities = 32/122 (26%), Positives = 67/122 (54%), Gaps = 1/122 (0%)
Query: 111 RRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREK 170
R + K KER+R RR+ + ++ R++K ++++R E K +R+ + RK + +
Sbjct: 527 RMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARE 586
Query: 171 KRERNRKERKKERERKERR-ERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFN 229
+ E+ ++E+KK+ E+K + + K E+ KE R +E+ K + ++ + R +E
Sbjct: 587 RVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEAR 646
Query: 230 RV 231
R+
Sbjct: 647 RL 648
Score = 28.5 bits (62), Expect = 6.7
Identities = 16/72 (22%), Positives = 33/72 (45%)
Query: 112 RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKK 171
+E ++ +E +E + + +K R+KKRR +++ R R+ +RK +
Sbjct: 38 QEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQLS 97
Query: 172 RERNRKERKKER 183
R R + E+
Sbjct: 98 SRRLRSKDSVEK 109
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 111 bits (277), Expect = 8e-25
Identities = 45/123 (36%), Positives = 94/123 (76%)
Query: 43 REKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKK 102
++K+K+++E E E + E+++ K+ +R ++R+ KRKE+EK++K + ++R+++++E+K
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 103 KRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKK 162
KR+RK++ ++E ++++E +E E E K+ E++ +RRKKK+++ RK E+E K++R+RK
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120
Query: 163 RKK 165
+KK
Sbjct: 121 KKK 123
Score = 110 bits (275), Expect = 1e-24
Identities = 51/129 (39%), Positives = 94/129 (72%), Gaps = 7/129 (5%)
Query: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKER 94
++KK+++E E+ + E E + E+ K K+KRK++ + KE+++K KE EK++++ E+++
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 95 RKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERG 154
RKRK++KKK E ER++++E +E E+E +++ E +R+K++KK+RRKE + EK++
Sbjct: 62 RKRKRKKKKEE------EEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK- 114
Query: 155 KRERKRKKR 163
KR RK KK+
Sbjct: 115 KRRRKTKKK 123
Score = 109 bits (272), Expect = 3e-24
Identities = 50/120 (41%), Positives = 86/120 (71%), Gaps = 1/120 (0%)
Query: 97 RKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKR 156
+KK+KKK+E ++ E +++E KE +R+ K++ +RK K+++KK + E+++EKE ++
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 157 ERKRK-KRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQT 215
+RKRK K+KKEE E++ E +E +KE E KE R+K++KK RRK++E +K +K R+T
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120
Score = 107 bits (267), Expect = 1e-23
Identities = 46/128 (35%), Positives = 90/128 (70%), Gaps = 5/128 (3%)
Query: 75 RERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK 134
+++K+K++E + E E+ + +KE K++E+++ R+E++KKK+ KE E+ ++ E K
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 135 RKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
++KR++KK+++E +RE+E + E +KEE EK+ R RK++KK R ++E E+KK+
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEE-----EEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115
Query: 195 RKKERRKK 202
R+++ +KK
Sbjct: 116 RRRKTKKK 123
Score = 103 bits (256), Expect = 2e-22
Identities = 43/131 (32%), Positives = 95/131 (72%), Gaps = 8/131 (6%)
Query: 51 EKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRG 110
+K++K+++ +E ++ ++ E +E+E KRKE+ K++++ +EK+++ ++ EK+K + ++
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 111 RRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREK 170
+R+RK+KK+++E ERE ++ E + K +E ++E+ R ++++K+++RK+EE EK
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEK--------EEEEKEEGRRRKKKKKRRRKEEEEEK 112
Query: 171 KRERNRKERKK 181
K++R RK +KK
Sbjct: 113 KKKRRRKTKKK 123
Score = 99.0 bits (245), Expect = 4e-21
Identities = 46/108 (42%), Positives = 81/108 (75%), Gaps = 2/108 (1%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
+ E E +KE + +EKRK E+ KE+++++ KE +KRK++E +E++RKRK ++K+ +E R
Sbjct: 18 ETEEEEEKEGKRKEKRK-EKRKEKEKKKKTKETEKRKEKEE-EEKKRKRKRKKKKEEEER 75
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138
E+E + ++EK++ E+++ RR++KKK+ RKE E E K++R RK KK+
Sbjct: 76 EEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 69.7 bits (169), Expect = 3e-12
Identities = 23/91 (25%), Positives = 67/91 (73%)
Query: 128 KQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKE 187
K+++++K++ ++ + + E++ GKR+ KRK+++KE+ +KK+ + ++RK++ E ++
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 188 RRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
+R+RK+++KKE +++E +++ + +++ + +
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEK 91
Score = 65.1 bits (157), Expect = 6e-11
Identities = 23/78 (29%), Positives = 59/78 (75%)
Query: 26 SKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
+K +R+ + ++E++ + KRK+++E+E + E ++E++++++ E+ + R RK+K++ ++
Sbjct: 46 TKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRR 105
Query: 86 RKERREKERRKRKKEKKK 103
++E EK++++R+K KKK
Sbjct: 106 KEEEEEKKKKRRRKTKKK 123
Score = 38.1 bits (87), Expect = 0.008
Identities = 15/56 (26%), Positives = 35/56 (62%)
Query: 170 KKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
KK+++ +KE ++ E +E E +++ K + K+KE++K+++ ++T R +E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE 56
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 110 bits (275), Expect = 1e-24
Identities = 67/208 (32%), Positives = 114/208 (54%), Gaps = 17/208 (8%)
Query: 25 ISKPCTQRESERKKERREREK-RKREREKERK-RERGKKEKKKRKKRERGKERERKRKER 82
+ P R +R++ER RE+ +RERE ER+ R R ++E + K RE + R R R R
Sbjct: 1125 VQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRR 1184
Query: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKE--------------RKERERENK 128
K+R + +EK+ K++K +++ K RK K +KE ER +
Sbjct: 1185 RKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAER 1244
Query: 129 QRRERKRKKRRKKKRRKERKREKERGK-RERKRKKRKKEEREKKRERNRKERKKERERKE 187
+ KR+K ++++ +KER++E ER + R+ +R+KR++ RE+ RER R+ + +R
Sbjct: 1245 AKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDR 1304
Query: 188 RRERKKERKKERRKKKERKKDRKTDRQT 215
RER +ER +ER ++ ++ R R T
Sbjct: 1305 DRERDRERGRERDRRDTKRHSRSRSRST 1332
Score = 98.6 bits (244), Expect = 5e-21
Identities = 62/206 (30%), Positives = 109/206 (52%), Gaps = 32/206 (15%)
Query: 28 PCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK 87
P Q + E+RE+E+ RE+ ER+RE + RER R ERE R
Sbjct: 1123 PPVQPPQHPRAEQREQERAVREQWAEREREM--------------ERRERTRSEREWDRD 1168
Query: 88 ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRK------- 140
+ RE R + + ++R+ + + + ++ +KKE+ + E K + RK +
Sbjct: 1169 KVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLP 1228
Query: 141 -------KKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKK 193
+K + +R KER KR +++++ +++EREK+ ER ER ++ ER++RRE +
Sbjct: 1229 LTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAER---ERNRQLEREKRREHSR 1285
Query: 194 ERKKERRKKKERKK-DRKTDRQTDSQ 218
ER +ER +++ER + DR DR+ D +
Sbjct: 1286 ERDRERERERERDRGDRDRDRERDRE 1311
Score = 78.2 bits (191), Expect = 7e-15
Identities = 44/166 (26%), Positives = 86/166 (51%), Gaps = 41/166 (24%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKE----------------------------- 62
R R ++RR +E+ K + +K K+E+ ++E
Sbjct: 1175 RSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQI 1234
Query: 63 -KKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER- 120
+K+ ++ ER KERE++RKE+E++ ++ REKE + + + +RE+++ RER +++ER
Sbjct: 1235 VQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERE 1294
Query: 121 ---------KERERENKQRRERKRKKRRKKKRRKERKRE-KERGKR 156
++RER+ ++ RER R+ ++ R + R ++RG R
Sbjct: 1295 RERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGR 1340
Score = 77.8 bits (190), Expect = 1e-14
Identities = 37/108 (34%), Positives = 72/108 (66%), Gaps = 6/108 (5%)
Query: 51 EKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRG 110
+KE +R KE++KR+K + +E E+K +E+E +R+ R+ ER KR++ ++R+R+
Sbjct: 1236 QKEAERAERAKEREKRRKEQ--EEEEQKEREKEAERERNRQLEREKRREHSRERDRE--- 1290
Query: 111 RRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRER 158
RER+++++R +R+R+ ++ RER R++ R+ +R R R + R+R
Sbjct: 1291 -RERERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDR 1337
Score = 75.1 bits (183), Expect = 6e-14
Identities = 36/106 (33%), Positives = 69/106 (65%), Gaps = 2/106 (1%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKK-EKKKRKKRERGKERERKR-KEREKQRKE 88
Q+E+ER + +EREKR++E+E+E ++ER K+ E+++ ++ ER K RE R ++RE++R+
Sbjct: 1236 QKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERER 1295
Query: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK 134
R++ R R +E+ + ++R RR+ K+ + R + R R+
Sbjct: 1296 ERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341
Score = 66.2 bits (160), Expect = 3e-11
Identities = 36/116 (31%), Positives = 69/116 (59%), Gaps = 5/116 (4%)
Query: 15 TELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERG-KKEKKKRKKRERGK 73
T+ Q+V + +R+KE+ E E+++RE+E ER+R R ++EK++ RER +
Sbjct: 1230 TDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDR 1289
Query: 74 ERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ 129
ERER ERE+ R + R+++R + ++ ++R+R+ R R + + R+R ++
Sbjct: 1290 ERER---ERERDRGD-RDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341
Score = 56.6 bits (135), Expect = 2e-08
Identities = 40/187 (21%), Positives = 87/187 (46%), Gaps = 2/187 (1%)
Query: 34 SERKKERREREKRKREREKERKRE-RGKKEKKKRKKRERGKERER-KRKEREKQRKERRE 91
SE K + + + RK ER R R+ R K + + E +++E R R + + +
Sbjct: 210 SEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKT 269
Query: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151
+E + ++E+++ + ++ G E +K +E + ++ E R K + + + R +
Sbjct: 270 EEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQ 329
Query: 152 ERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKT 211
E+ ER + + +E +K R++++KE + E ++ K + KE+ K
Sbjct: 330 EQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSP 389
Query: 212 DRQTDSQ 218
R T+ +
Sbjct: 390 PRLTEDR 396
Score = 50.1 bits (118), Expect = 2e-06
Identities = 38/174 (21%), Positives = 79/174 (45%), Gaps = 10/174 (5%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERG-KERERKRKEREKQRKER 89
+R S R ++ R + + + E + ++ + R + +R K E + +E E++ +
Sbjct: 225 ERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDE 284
Query: 90 REK---ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
E+ E +K ++ +E K+ G + K E ER + +E++ +R + R +
Sbjct: 285 EEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQ 344
Query: 147 RKREKERGKRERKRKKRK------KEEREKKRERNRKERKKERERKERRERKKE 194
+ K R+++ K+ K +EERE K + KE+ K E +K+
Sbjct: 345 EEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKK 398
Score = 48.1 bits (113), Expect = 8e-06
Identities = 45/221 (20%), Positives = 94/221 (42%), Gaps = 20/221 (9%)
Query: 3 KAISSRAAVKLNTEL-QMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKK 61
K + AA + N+++ + +S + K +++ E ++R ERE R+ +E E +
Sbjct: 113 KHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDE 172
Query: 62 E--------------KKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERK 107
+ ++ E R RK ++ + + RK E++ R
Sbjct: 173 MIHPEGVASLLPPDFQSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRS-SRV 231
Query: 108 QRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEE 167
++ R + + + E E+++ R + R + + E + E+E + E ++ +E
Sbjct: 232 RQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDE 291
Query: 168 REKKRE----RNRKERKKERERKERRERKKERKKERRKKKE 204
+K RE + KE +E R + E ER K R +++E
Sbjct: 292 GQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQE 332
Score = 47.0 bits (110), Expect = 2e-05
Identities = 32/157 (20%), Positives = 74/157 (47%), Gaps = 2/157 (1%)
Query: 26 SKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
S+P + E + R R + R + E + E ++E+++ + E G + +K +E
Sbjct: 243 SQPAEEEEDQETPSRNLRVRADRNLKTEEEEEE-EEEEEEDDEEEEGDDEGQKSREAPIL 301
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
++ + E E R K ++ + + + R + ++ ER R +++ + R+++++
Sbjct: 302 KEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEM 361
Query: 146 ERKREKERGKRERKRKKRKKEE-REKKRERNRKERKK 181
+ E +RE K + KE+ + R ++RKK
Sbjct: 362 KTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKK 398
Score = 42.4 bits (98), Expect = 4e-04
Identities = 42/194 (21%), Positives = 82/194 (42%), Gaps = 20/194 (10%)
Query: 45 KRKREREKERKRERGKKEKKKRKKRERGK-ERERKRKERE----------KQRKERREKE 93
K+ E+++E R+R ++E ++ + E E E + E + ER E E
Sbjct: 138 KQYLEKQQELLRQRLEREAREAAELEEASAESEDEMIHPEGVASLLPPDFQSSLERPELE 197
Query: 94 RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153
+ K +++G + +K ++ + R +Q R K + + +E + R
Sbjct: 198 LSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSR 257
Query: 154 GKRER-----KRKKRKKEEREK----KRERNRKERKKERERKERRERKKERKKERRKKKE 204
R R K ++ ++EE E+ + E E +K RE +E K+E ++ R K E
Sbjct: 258 NLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPE 317
Query: 205 RKKDRKTDRQTDSQ 218
D + ++ Q
Sbjct: 318 EMMDERPKTRSQEQ 331
Score = 37.4 bits (85), Expect = 0.014
Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 37 KKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRK 96
K+ + E E+ R + +E ER K ++++ ERG R ++E K R+++E
Sbjct: 302 KEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQE--- 358
Query: 97 RKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE 152
KE K + RE K + KE+ + R + +K+ E+ +E
Sbjct: 359 --KEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEE 412
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 108 bits (270), Expect = 5e-24
Identities = 54/182 (29%), Positives = 117/182 (64%), Gaps = 6/182 (3%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
RE E K R+E+ R++E+E + + +++KK R++ E+ +E+E K E+E++ +E+ E
Sbjct: 272 REQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE 331
Query: 92 KERR------KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
K R +++K+ +++E+K R + ER +++ + RE+E + R + K ++ +K + +
Sbjct: 332 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEE 391
Query: 146 ERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKER 205
ER RE+E+ RE + R++EE+ +K+E N E++++ +++R +KE+ E+ K +E+
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
Query: 206 KK 207
++
Sbjct: 452 EE 453
Score = 102 bits (254), Expect = 4e-22
Identities = 61/222 (27%), Positives = 138/222 (62%), Gaps = 11/222 (4%)
Query: 4 AISSRAAVKLNTE--LQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKK 61
A S ++ ++LN + + + + P Q + +++ R+ E+ + + +K RK+E
Sbjct: 199 AESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMW 258
Query: 62 EKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERK 121
+++R + + GK RE++ K R +Q K RE+E+ R++EK+ RE+K+ R+++++ +
Sbjct: 259 RQEERLREQEGKMREQEEKMR-RQEKRLREQEKELREQEKELREQKKL----REQEEQMQ 313
Query: 122 ERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEER---EKKRERNRKE 178
E+E + ++ E+ R++ K R++ER E+E+ RE+++K R +EER + +R R ++E
Sbjct: 314 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 373
Query: 179 RKKERERK-ERRERKKERKKERRKKKERKKDRKTDRQTDSQV 219
R +E+E+ E+ E+ +E ++ R ++K+ +++ +T R+ + ++
Sbjct: 374 RMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKM 415
Score = 101 bits (251), Expect = 8e-22
Identities = 49/183 (26%), Positives = 117/183 (63%), Gaps = 1/183 (0%)
Query: 36 RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERR 95
+++E RE+EK+ R++E++ R+ + +++ K RE+ ++ R+ K +Q KE RE+E+
Sbjct: 239 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKE 298
Query: 96 KRKKEKKKRERKQRGRRERKK-KKERKERERENKQRRERKRKKRRKKKRRKERKREKERG 154
R+++K + + +Q +E K ++E K RE+E K R+ +R ++K+ R++ ++ +++
Sbjct: 299 LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 358
Query: 155 KRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQ 214
+R ++ +R +E+ E+ RE+ + ++E+ ++E R R++E+K ++ R+++ K +Q
Sbjct: 359 ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 418
Query: 215 TDS 217
++
Sbjct: 419 EEN 421
Score = 99.4 bits (246), Expect = 3e-21
Identities = 63/197 (31%), Positives = 129/197 (65%), Gaps = 15/197 (7%)
Query: 32 RESERKKERREREK--RKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
RE E KK R++ EK R+ ER +E++ + ++E+K R++ +R +E+E++ +E+EK+ +E+
Sbjct: 244 REQE-KKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ 302
Query: 90 ---REKERRKRKKEKKKRERKQRGRRERKKKKERKER-ERENKQRRERKRKKRRKKKR-- 143
RE+E + +++E+K E++++ R + +K ++ER + KQ RE+++K R +++R
Sbjct: 303 KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 362
Query: 144 -RKERKREKERGKRERKR---KKRKKEEREKKRERNRKERKKERERKERRER--KKERKK 197
+ ER REKE RE+++ ++ K +E E+ RER +K R++E +E+ E+ K+E
Sbjct: 363 EQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 422
Query: 198 ERRKKKERKKDRKTDRQ 214
+++KE ++ R +++
Sbjct: 423 WEQEEKEWQQQRLPEQK 439
Score = 97.1 bits (240), Expect = 2e-20
Identities = 54/200 (27%), Positives = 121/200 (60%), Gaps = 6/200 (3%)
Query: 32 RESERK---KERREREKRKREREK-ERKRERGKKEKKKRKKRERGKERERKRKEREKQRK 87
R+ E+K +E R E+ +R REK ER RE+ K +++ K RE K +E+++K +++ K
Sbjct: 496 RDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEK 555
Query: 88 ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENK--QRRERKRKKRRKKKRRK 145
R E+ R+R+K+ ++ E R + E+ +++E K RE+E K ++ E+ +++ K ++
Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
Query: 146 ERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKER 205
E+ E+E + +++++ E+ EK +E+ K ++E + +E+ E+ +E++++ + ++E+
Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 675
Query: 206 KKDRKTDRQTDSQVFRPLRE 225
++++ Q + R E
Sbjct: 676 MREQEEKMQGQEEKMREQEE 695
Score = 94.7 bits (234), Expect = 8e-20
Identities = 57/203 (28%), Positives = 117/203 (57%), Gaps = 15/203 (7%)
Query: 31 QRESERKKERREREKRKREREKERKRERGK---KEKKKRKKRERGKERERKRKEREKQRK 87
Q E R+KE R RE+ K ++E+ +E + +EKK R++ E +E+E K +++E+
Sbjct: 364 QDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 423
Query: 88 ERREKE----RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKR 143
E+ EKE R +KEK + K + + E+ ++E K R++E +E+K ++ K +
Sbjct: 424 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 483
Query: 144 RKERKREKERGKRERKRKKRKKEER--------EKKRERNRKERKKERERKERRERKKER 195
++++ E+E R++++K +EER +K ER R+++K ++ ++ RE KK +
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQ 543
Query: 196 KKERRKKKERKKDRKTDRQTDSQ 218
++E++ + +K R+ +R + +
Sbjct: 544 EQEKKTWDQEEKMREEERMRERE 566
Score = 94.7 bits (234), Expect = 8e-20
Identities = 49/188 (26%), Positives = 122/188 (64%), Gaps = 5/188 (2%)
Query: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK-- 92
E++K + + EK + EK R +E ++KK ++E+ +E+E + E+E++ +++ +K
Sbjct: 444 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 503
Query: 93 --ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
E R +++++ RE+++R RE+KK +++E+ RE K+ +E+++K ++++ +E +R
Sbjct: 504 DQEERMWEQDERLREKEER-MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM 562
Query: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRK 210
+ER K+ R+ ++ +E+ EK +E+ K R++E + E+ E+ +E++++ +++E+ +++
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622
Query: 211 TDRQTDSQ 218
+ + Q
Sbjct: 623 EEDKMQEQ 630
Score = 94.0 bits (232), Expect = 1e-19
Identities = 50/189 (26%), Positives = 124/189 (65%), Gaps = 6/189 (3%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
+R E+ + RE+E+R RE++K ++E +E+KK +++E+ K +++ K RE++R R
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEK-KTWDQEEKMREEERMRER 565
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENK-QRRERKRKKRRKK---KRRKE 146
EK+ R+ ++ +++E K + + E+ +++E K E+E K Q +E K ++ +K + ++
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
Query: 147 RKREKERGKRERKRKKRKKEERE-KKRERNRKERKKERERKERRERKKERKKERRKKKER 205
+ +E+E E++ K +++EE+ ++ E+ R++ +K RE++E+ + ++E+ +E+ +K +
Sbjct: 626 KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQG 685
Query: 206 KKDRKTDRQ 214
++++ +++
Sbjct: 686 QEEKMREQE 694
Score = 93.6 bits (231), Expect = 2e-19
Identities = 51/200 (25%), Positives = 122/200 (61%), Gaps = 6/200 (3%)
Query: 32 RESERKKERREREKRKREREKERKRER-GKKEKKKRKKRERGKERERKRKEREKQRKERR 90
RE E + +E + R +E++ + ER +++++ R+K ER +E+++ ++ EK R+E++
Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKK 541
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKE---RERENK--QRRERKRKKRRKKKRRK 145
+E+ K+ +++++ R++ RER+KK +E RE+E K ++ E+ R++ K ++
Sbjct: 542 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE 601
Query: 146 ERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKER 205
E+ +E+E E++ K ++EE +K +E+ ++E + +E+ E+ E++++ R+++E+
Sbjct: 602 EKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK 661
Query: 206 KKDRKTDRQTDSQVFRPLRE 225
++++ Q + R E
Sbjct: 662 MREQEEKMQGQEEKMREQEE 681
Score = 93.6 bits (231), Expect = 2e-19
Identities = 54/199 (27%), Positives = 120/199 (60%), Gaps = 19/199 (9%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRK---------KRERGKERERKRKE 81
Q E R+KE R RE++K +++E+ RE K +++++K + ER +ERE+K +E
Sbjct: 512 QDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 571
Query: 82 REKQRKERREK----ERRKRKKEKKKRERKQRGRRERKKKKERKER----ERENKQRRER 133
E+ +E+ EK E + R++E+K E++++ + + +K E++E+ E E+K + +
Sbjct: 572 EEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQE 631
Query: 134 KR--KKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRER 191
+ ++ K + ++E+ E+E RE++ K R++EE+ + +E +E++++ + +E + R
Sbjct: 632 EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMR 691
Query: 192 KKERKKERRKKKERKKDRK 210
++E K +++K ++ K
Sbjct: 692 EQEEKMRGQEEKMWGQEEK 710
Score = 93.2 bits (230), Expect = 2e-19
Identities = 51/200 (25%), Positives = 122/200 (61%), Gaps = 12/200 (6%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
T RE E K +++E ++E EKE +++R ++K+K ++E+ +E+E K E+E++ +++
Sbjct: 407 TMREQEEKMQKQEENMWEQE-EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 465
Query: 90 RE---------KERRKRKKEKKKRERKQRGRRERKKKKERKER--ERENKQRRERKRKKR 138
E ++ + R++E + E++++ R + +K +++ER E++ + R + +R +
Sbjct: 466 EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMRE 525
Query: 139 RKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKE 198
+KK ++E K +E+ +E+++K +EE+ ++ ER R+ KK RE +E ++E+ +E
Sbjct: 526 QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 585
Query: 199 RRKKKERKKDRKTDRQTDSQ 218
+ +K ++++ +++ Q
Sbjct: 586 QEEKMREQEEKMWEQEEKMQ 605
Score = 92.8 bits (229), Expect = 3e-19
Identities = 58/216 (26%), Positives = 127/216 (58%), Gaps = 21/216 (9%)
Query: 31 QRESERKKERREREKRKREREKERKRER-GKKEKKKRKKRERGKERERKRKEREKQRKER 89
+R E+++ RE+EK + EK ++ ER ++EKK R++ E +E+E K +++E+ E+
Sbjct: 366 ERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 425
Query: 90 REKE----RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
EKE R +KEK + K + + E+ ++E K R++E +E+K ++ K + ++
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 485
Query: 146 ERKREKERGKRERKRKKRKKEER---EKKRERNRKERKKERE---------RKERRERKK 193
++ E+E R++++K +EER + +R R ++ER +E++ R+E++ +++
Sbjct: 486 DQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQ 545
Query: 194 ERK----KERRKKKERKKDRKTDRQTDSQVFRPLRE 225
E+K +E+ +++ER ++R+ + + ++ R E
Sbjct: 546 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEE 581
Score = 92.4 bits (228), Expect = 4e-19
Identities = 55/193 (28%), Positives = 118/193 (61%), Gaps = 6/193 (3%)
Query: 27 KPCTQRESERKKER-REREKRKRERE---KERKRERGKKEKKKRKKRERGKERERKRKER 82
K Q E R++ER REREK+ RE E +E++ + ++E+K R++ E+ E+E K +E+
Sbjct: 548 KTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ 607
Query: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRERK-KKKERKERERENKQRRERKRKKRRKK 141
E++ E+ EK + +++K + + + +E K +++E K E+E K R + ++ + +++
Sbjct: 608 EEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 667
Query: 142 KRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
K + + ++ +E+ ++ + ++++ +E+ EK R + K +E E+ +E K ++E R+
Sbjct: 668 KMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQE-EKMWGQEEKMWGQEEMRE 726
Query: 202 KKERKKDRKTDRQ 214
K+ER +D+K Q
Sbjct: 727 KEERIRDQKEKMQ 739
Score = 92.0 bits (227), Expect = 5e-19
Identities = 56/196 (28%), Positives = 120/196 (61%), Gaps = 14/196 (7%)
Query: 27 KPCTQRESERKKERREREKRKREREKERKR-ERGKKEKKKRKKRERGKER--ERKRKERE 83
K ++E E +++++ RE+ ++ +E+E K E+ +K +++ +K R +ER E++++ RE
Sbjct: 290 KELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE 349
Query: 84 KQRKERREKER------RKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKK 137
+++K R ++ER R R+KE++ RE+++ +E K ++E + RERE K R E + +
Sbjct: 350 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMR 409
Query: 138 RRKKKRRKE-----RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERK 192
+++K +K+ + EKE ++ +K K E+EK +E+ K ++E + +++ E
Sbjct: 410 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 469
Query: 193 KERKKERRKKKERKKD 208
+ KK R++K R+++
Sbjct: 470 GQEKKMWRQEKMREQE 485
Score = 92.0 bits (227), Expect = 5e-19
Identities = 53/211 (25%), Positives = 125/211 (59%), Gaps = 23/211 (10%)
Query: 31 QRESERKKER-REREKRKRE-----REKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
Q E +++ER REREK+ RE RE+E K ++ ++ +++++E ++R ++KE+
Sbjct: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 443
Query: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK-- 142
++++ +E+E + ++E+K R++++ +E+K ++ K RE+E++ + ++ + +++K
Sbjct: 444 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 503
Query: 143 -------RRKERKREKERGKRERKR--------KKRKKEEREKKRERNRKERKKERERKE 187
+ ER REKE RE+K+ ++ KK + ++K+ +++E+ +E ER
Sbjct: 504 DQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563
Query: 188 RRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
RE+K ++E +++E K + ++ + +
Sbjct: 564 EREKKMREEEEMMREQEEKMQEQEEKMREQE 594
Score = 90.5 bits (223), Expect = 1e-18
Identities = 59/200 (29%), Positives = 119/200 (59%), Gaps = 19/200 (9%)
Query: 31 QRESERKKERREREKRKREREKE-RKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Q + R +E R E+ +R REKE R RE+ K +++ K +E + RER++K RE++ R
Sbjct: 350 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMR 409
Query: 90 REKERRKRKK----EKKKRERKQRGRRERKKK---------KERKERERENKQRRERKRK 136
++E+ ++++ E++++E +Q+ E+K+K +E K E+E K R + +
Sbjct: 410 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 469
Query: 137 KRRKKKRRKERKREKERGKRERKRKKRKKEER-----EKKRERNRKERKKERERKERRER 191
+ KK R+E+ RE+E E++ K R +E++ E+ E++ + R+KE +E+++
Sbjct: 470 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKM 529
Query: 192 KKERKKERRKKKERKKDRKT 211
++ +K R +KK +++++KT
Sbjct: 530 WQQEEKMREEKKTQEQEKKT 549
Score = 89.7 bits (221), Expect = 2e-18
Identities = 54/218 (24%), Positives = 126/218 (57%), Gaps = 18/218 (8%)
Query: 31 QRESERKKERREREKRKREREKER-KRERGKKEKK------KRKKRERGKERERKRKERE 83
++E + ++E R RE+ K+ RE+E RE+ +K +K +++++E ++R ++KE+
Sbjct: 383 EQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 442
Query: 84 KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK- 142
++++ +E+E + ++E+K R++++ +E+K ++ K RE+E++ + ++ + +++K
Sbjct: 443 WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 502
Query: 143 --------RRKERKREKERGKRERKR--KKRKKEEREKKRERNRKERKKERERKERRERK 192
+ ER REKE RE+K+ ++ +K EKK + K+ + E+ ER
Sbjct: 503 WDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM 562
Query: 193 KERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNR 230
+ER+K+ R+++E ++++ Q + R E + +
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600
Score = 89.7 bits (221), Expect = 2e-18
Identities = 48/189 (25%), Positives = 118/189 (62%), Gaps = 15/189 (7%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEK-----KKRKKRERGKERERKRKEREK--- 84
E E+ +E+ E+ + E+ ++++ G+++K K R++ ++ E+E K +++E+
Sbjct: 444 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 503
Query: 85 -QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENK------QRRERKRKK 137
Q + E++ R R+KE++ RE+K+ ++E K ++E+K +E+E K + RE +R +
Sbjct: 504 DQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563
Query: 138 RRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKK 197
R+KK R+E + +E+ ++ ++++++ +E+ EK E+ K +++E + E+ E+ E+++
Sbjct: 564 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 623
Query: 198 ERRKKKERK 206
E + +++ +
Sbjct: 624 EDKMQEQEE 632
Score = 89.4 bits (220), Expect = 3e-18
Identities = 53/187 (28%), Positives = 117/187 (62%), Gaps = 14/187 (7%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERG-------KERERKRKEREK- 84
+ E+ +E+ E+ R+ ER E++++ ++E+K R + ER +E+E + +E+EK
Sbjct: 322 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 381
Query: 85 -QRKERREKERRKRKKEKKKRERKQ--RGRRERKKKKERKERERENKQRRERKRKKRRKK 141
+++E+ ++E R R++EKK RE ++ R + E+ +K+E E+E K+ ++++ ++++K
Sbjct: 382 WEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441
Query: 142 KRRKERKREKERGKRERKRKKRKKEE---REKKRERNRKERKKERERKERRERKKERKKE 198
+E+ +E+E E++ K R +EE +EKK R K R++E + E+ E+ ++++++
Sbjct: 442 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 501
Query: 199 RRKKKER 205
++ER
Sbjct: 502 MWDQEER 508
Score = 84.7 bits (208), Expect = 8e-17
Identities = 50/210 (23%), Positives = 123/210 (58%), Gaps = 15/210 (7%)
Query: 31 QRESERKKER---REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK 87
Q E R +E +E++ ++E+ +E++ + ++E+K R + ++ ++E + E++++ +
Sbjct: 458 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLR 517
Query: 88 ERREKERRKRK---KEKKKRERKQRGRRER-------KKKKERKERERENKQRRERK--R 135
E+ E+ R ++K +E+K RE K+ +E+ K ++E + RERE K R E + R
Sbjct: 518 EKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 577
Query: 136 KKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKER 195
++ K + ++E+ RE+E E++ K +++EE+ ++E E+++E + +E+ E E+
Sbjct: 578 EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQ 637
Query: 196 KKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
+++ ++++E+ +++ + + R E
Sbjct: 638 EEKMQEQEEKMWEQEEKMREQEEKMREQEE 667
Score = 82.8 bits (203), Expect = 3e-16
Identities = 56/218 (25%), Positives = 120/218 (55%), Gaps = 27/218 (12%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGK------ERERKRKERE 83
T E KK+ E +++ R E E K E K+ ++K ER K + ++E
Sbjct: 179 TITNEELKKKNAELQEKLRLAESE-KSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMW 237
Query: 84 KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKER-ERENKQRRERKRKKRRKKK 142
+Q +E RE+E++ RK+E+K +++R R + K +E++E+ R+ K+ RE++++ R ++K
Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK 297
Query: 143 RRKERKREKERGKRERKRKKRKKEEREKKRERNRK---------ERKKERERKERRERKK 193
+E+K+ +E+ ++ ++++++ E+ EK RE+ K E++K+ +E++ R +
Sbjct: 298 ELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 357
Query: 194 E----------RKKERRKKKERKKDRKTDRQTDSQVFR 221
E R+KE R +++ K + ++ + + R
Sbjct: 358 EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIR 395
Score = 77.8 bits (190), Expect = 1e-14
Identities = 41/166 (24%), Positives = 99/166 (59%), Gaps = 5/166 (3%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Q + E+ +E+ E+ + E+ +E++ + ++E+K ++ E K +E++ E++ K +
Sbjct: 584 QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEK-MQ 642
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
E+E + ++E+K RE++++ R + +K + ++E+ RE +++ + + +K R+++ + + E
Sbjct: 643 EQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEE 702
Query: 151 KERGKRER----KRKKRKKEEREKKRERNRKERKKERERKERRERK 192
K G+ E+ + K +EE +K ER R +++K +ER E +
Sbjct: 703 KMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEER 748
Score = 67.8 bits (164), Expect = 1e-11
Identities = 51/189 (26%), Positives = 103/189 (54%), Gaps = 14/189 (7%)
Query: 37 KKERREREKRKREREK---ERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93
KK R E+ +ER+ E R E+ K+K E ++ E+ + + +E +
Sbjct: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
Query: 94 RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153
R+ + + + + +E ++E + RE+E K RK+ K R++ER RE+E
Sbjct: 215 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK-----IRKQEEKMWRQEERLREQEG 269
Query: 154 GKRERKRKKRKKEEREKKRERNRKERKKE-RERKERRERKKERKKERRK-----KKERKK 207
RE++ K R++E+R +++E+ +E++KE RE+K+ RE++++ +++ K +K R++
Sbjct: 270 KMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQ 329
Query: 208 DRKTDRQTD 216
+ K RQ +
Sbjct: 330 EEKMWRQEE 338
Score = 67.8 bits (164), Expect = 1e-11
Identities = 43/153 (28%), Positives = 91/153 (59%), Gaps = 4/153 (2%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
++ E++++ E+E++ E+E+E K + ++E+ ++ E+ +E+E K E+E++ +E+
Sbjct: 602 EKMQEQEEKMWEQEEKMWEQEEEDKMQ--EQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 659
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR-RERKRKKRRKKKRRKERKR 149
EK R + +K + +E K R + E+ + +E K RE+E K R +E K + +K +E K
Sbjct: 660 EKMREQEEK-MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKM 718
Query: 150 EKERGKRERKRKKRKKEEREKKRERNRKERKKE 182
+ RE++ + R ++E+ ++R +ER E
Sbjct: 719 WGQEEMREKEERIRDQKEKMQERLPEHEERCSE 751
Score = 56.6 bits (135), Expect = 2e-08
Identities = 38/153 (24%), Positives = 83/153 (54%), Gaps = 11/153 (7%)
Query: 76 ERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135
E KER+ E + +KK E +++ R +K E + +E K++ ER +
Sbjct: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAK 221
Query: 136 ---------KKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERK 186
+ + R++E RE+E+ R+++ K ++EER +++E +E++++ R+
Sbjct: 222 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQ 281
Query: 187 ERRERKKERKKERRKKKERKKDRKTDRQTDSQV 219
E+R R E++KE R++++ +++K R+ + Q+
Sbjct: 282 EKRLR--EQEKELREQEKELREQKKLREQEEQM 312
Score = 33.9 bits (76), Expect = 0.16
Identities = 41/211 (19%), Positives = 85/211 (40%), Gaps = 23/211 (10%)
Query: 26 SKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
S+ C E E+K + +E +RE E + R +K + ++ RK +
Sbjct: 63 SEGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGN 122
Query: 86 RKERREKERR-----------KRKKEKKKRERKQRGRRERKKKKERKERERE-------N 127
E ++ R +R K+ R + KER E N
Sbjct: 123 LGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITN 182
Query: 128 KQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKE 187
++ +++ + + K + + K E + +E KRK + + + + N + + R+ +E
Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242
Query: 188 RRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
RE++K + +K+E K R+ +R + +
Sbjct: 243 LREQEK-----KIRKQEEKMWRQEERLREQE 268
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 107 bits (266), Expect = 1e-23
Identities = 55/199 (27%), Positives = 127/199 (63%), Gaps = 6/199 (3%)
Query: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKER 94
ER ++ +E +K++ E++ + E+ +K K++R E+ K++ +K E + + ++E+E
Sbjct: 582 ERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEA 641
Query: 95 RKRKKEKKKRERKQRGRRERKKKKERKERER---ENKQRRERKRKKRRKKKRRKERKREK 151
R+ + +++ E ++ +KKK+E +ER R E K+ E++ ++RR+++RR++ +RE+
Sbjct: 642 RRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQ 701
Query: 152 ERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER---RKKKERKKD 208
ER ++ER+ ++R+ E+E++RE+ R + ++E + +E+ R ++ + +R KKK+ ++
Sbjct: 702 ERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 761
Query: 209 RKTDRQTDSQVFRPLRESA 227
R +RQ + + +E+A
Sbjct: 762 RLAERQLQEEQEKKAKEAA 780
Score = 102 bits (254), Expect = 4e-22
Identities = 65/228 (28%), Positives = 132/228 (57%), Gaps = 20/228 (8%)
Query: 11 VKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRE 70
VKL E ++ + Q + E+KK+ ++ + E+ ++ K ER +EK K+K
Sbjct: 566 VKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAA 625
Query: 71 RGKER-ERKRKEREKQRK----ERREKERR------KRKKEKKKRERKQ-------RGRR 112
+ E E +RK+ E+ R+ ++ E+ERR K+K+E+++R RK R
Sbjct: 626 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQRE 685
Query: 113 ERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKR 172
+ ++++ER+E+ER ++RRE++R+++ ++ +ER+RE+ER + ER+ ++R+K R +K
Sbjct: 686 QERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKE 745
Query: 173 ERNRK--ERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
+ R+ E+KK+ E++ ER+ + ++E++ K+ + + D Q
Sbjct: 746 QLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQ 793
Score = 99.0 bits (245), Expect = 4e-21
Identities = 58/215 (26%), Positives = 131/215 (60%), Gaps = 14/215 (6%)
Query: 8 RAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRK 67
++ +K NT L+M K ++ E + + E E+ +R++ +E KR R ++ K KR+
Sbjct: 517 KSFIKRNTPLRMDP-----KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE 571
Query: 68 KRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKEREREN 127
+R R + R+R E+ K+ K+++ +++ + EK ++ +++R E+ KKK ++ E
Sbjct: 572 ERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEV 631
Query: 128 KQRRERKRKKRR--------KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKER 179
+ RR+++ + RR +++R +E ++K+ ++ER RK + + ++RE+ R+E+
Sbjct: 632 EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 691
Query: 180 -KKERERKERRERKKERKKERRKKKERKKDRKTDR 213
++E+ER+E+ R++ER+++ R+ E+++ R+ +R
Sbjct: 692 ERREQERREQERREQERREQERQLAEQERRREQER 726
Score = 91.3 bits (225), Expect = 8e-19
Identities = 63/214 (29%), Positives = 123/214 (57%), Gaps = 17/214 (7%)
Query: 23 SHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKER 82
S I + R ++KER+ E +R+ E E+ R R K E+ KR++ E E K K
Sbjct: 518 SFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLR-RQKVEEDKRRRLE-----EVKLKRE 571
Query: 83 EKQRKERREKERRKRKKEKKKRERKQR-GRRERKKKKERKERERENKQRRERKRKKRRKK 141
E+ RK + +ER ++ KE+KK++ +Q+ + + K +K ++ER E K +++ KK +
Sbjct: 572 ERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEV 631
Query: 142 KRRKERKREKERGK--RERKRKKRKKEEREKKRE------RNRKERKKERERKERRERKK 193
+ R++++ E R + ++ + ++R +E +KK+E R E K+ E++E+ R++
Sbjct: 632 EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 691
Query: 194 ERKKERRKKKERKKD--RKTDRQTDSQVFRPLRE 225
ER+++ R+++ER++ R+ +RQ Q R +E
Sbjct: 692 ERREQERREQERREQERREQERQLAEQERRREQE 725
Score = 53.9 bits (128), Expect = 1e-07
Identities = 30/114 (26%), Positives = 65/114 (57%), Gaps = 1/114 (0%)
Query: 119 ERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKE 178
+ KER+R RR+ + ++ R++K ++++R E K +R+ + RK + ++ E+ ++E
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
Query: 179 RKKERERKERR-ERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRV 231
+KK+ E+K + + K E+ KE R +E+ K + ++ + R +E R+
Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 644
Score = 28.5 bits (62), Expect = 6.7
Identities = 16/72 (22%), Positives = 33/72 (45%)
Query: 112 RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKK 171
+E ++ +E +E + + +K R+KKRR +++ R R+ +RK +
Sbjct: 38 QEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQLS 97
Query: 172 RERNRKERKKER 183
R R + E+
Sbjct: 98 SRRLRSKDSVEK 109
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 106 bits (264), Expect = 3e-23
Identities = 53/189 (28%), Positives = 96/189 (50%), Gaps = 2/189 (1%)
Query: 34 SERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93
S R + R R RE++RK + ++ + R + + G+ E K K +K + E +
Sbjct: 32 SPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDK 91
Query: 94 RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR-RKKKRRKERKREKE 152
K +++ + G K+K+ + R R + + R R+R+ R R ++R+K R R +E
Sbjct: 92 EHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE 151
Query: 153 RGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTD 212
R K+ R R + +K+ R + RER R+ R + R R R R + R + R + ++RKK +
Sbjct: 152 R-KKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKP 210
Query: 213 RQTDSQVFR 221
R+ + R
Sbjct: 211 RRFSRSLSR 219
Score = 105 bits (262), Expect = 4e-23
Identities = 61/199 (30%), Positives = 98/199 (49%), Gaps = 4/199 (2%)
Query: 32 RESERKKERREREKRKREREKERKRERGK-KEKKKRKKRERGKERERKRKEREKQRKERR 90
RE +RK + R+ R R R KE +R K K KK K E + K RE+
Sbjct: 48 RERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSEN 107
Query: 91 EKERRKRKKEKKKRERKQ-RGR-RERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
++R KRK+ K R R R R RER+ + +ER++ + RERK+ + R ++R+K R
Sbjct: 108 GEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRS 167
Query: 149 REKERGKRERKRKKRKKEEREKKRERNR-KERKKERERKERRERKKERKKERRKKKERKK 207
R +ER +R R R + + R + R R+R + R ++R+++ + R+ R R +
Sbjct: 168 RSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFR 227
Query: 208 DRKTDRQTDSQVFRPLRES 226
R T + R L +
Sbjct: 228 GRNTAMDAQEALARRLERA 246
Score = 104 bits (259), Expect = 1e-22
Identities = 66/224 (29%), Positives = 109/224 (48%), Gaps = 11/224 (4%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
T + ++KKE+ E R + R R + ++KRK G++ + + +E +R E
Sbjct: 16 TSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHES 75
Query: 90 REKERRKRKKEKKK-RERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
++K +K K E+ +E RER E E + +R+ERK + R R + R+
Sbjct: 76 KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGE---DRHKRKERKSSRGRSHSRSRSRE 132
Query: 149 REKERGKRERKRKKRKKEEREKKRERNR---KERKKERERKER-RERKKERKKERRKKKE 204
R RERK+ + + ER+K R R+R K R + RERK R R R + R + R + +
Sbjct: 133 RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRS 192
Query: 205 RKKDRKTDRQTDSQVFRPLRES-AFNRVTVTGVFRYRIFHTGLD 247
R + R R ++ +P R S + +R FR R +T +D
Sbjct: 193 RSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGR--NTAMD 234
Score = 95.5 bits (236), Expect = 4e-20
Identities = 55/189 (29%), Positives = 93/189 (49%), Gaps = 19/189 (10%)
Query: 34 SERKKERREREKRKREREKERKRER---GKKEKKKRKKRERGKERERKRKEREKQRKERR 90
S+ +++ EK +R+K++++ + K R R + RERKRK + RK R
Sbjct: 4 SDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRS 63
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
R R KE ++ E K + ++ K + E ++E + + RER + R K ++R+
Sbjct: 64 ----RSRSKEGRRHESKDKSSKKHKSE-EHNDKEHSSDKGRERLNSSENGEDRHKRKERK 118
Query: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRK 210
RG+ + R R R+ R + RERK+ R R +ERKK R + +ERKK R
Sbjct: 119 SSRGR-----------SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRS 167
Query: 211 TDRQTDSQV 219
R+ ++
Sbjct: 168 RSRERKRRI 176
Score = 86.7 bits (213), Expect = 2e-17
Identities = 47/180 (26%), Positives = 94/180 (52%), Gaps = 9/180 (5%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKK---RERGKERERKRKEREKQRKER 89
E KE + R+R E +R K++++K + R + RER+ + R ++RK+
Sbjct: 86 EEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKS 145
Query: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
R + R ++K + RERK+ R R++K+ + R R + R R R + R + R ++RK+
Sbjct: 146 RSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKK 205
Query: 150 EKERGKRERKRKKRKKEE---REKKRERNRKE---RKKERERKERRERKKERKKERRKKK 203
E+ +R + R R + + +E R+ ER +K + +R+KE +++++++
Sbjct: 206 RIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
Score = 84.3 bits (207), Expect = 1e-16
Identities = 57/202 (28%), Positives = 97/202 (48%), Gaps = 27/202 (13%)
Query: 32 RESERKKERREREKRKREREKERKRERGK-----------KEKKKRKKRERGKERERKR- 79
R E K + ++ K + +KE ++G+ + K+K +K RG+ R R
Sbjct: 71 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 130
Query: 80 KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR 139
+ER + + R K+ R R +E+K K R R +KK + RER +RR R R + R
Sbjct: 131 RERRHRSRSRERKKSRSRSRERK----KSRSRSRERKKSRSRSRER---KRRIRSRSRSR 183
Query: 140 KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNR-------KERKKERERKERRERK 192
+ R + R R + R R R RKKR ++ R R +R + R + +E R+
Sbjct: 184 SRHRHRTRSRSRTR-SRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARR 242
Query: 193 KERKKERRKKKERKKDRKTDRQ 214
ER K+ ++++E++ K +Q
Sbjct: 243 LERAKKLQEQREKEMVEKQKQQ 264
Score = 75.1 bits (183), Expect = 6e-14
Identities = 43/161 (26%), Positives = 80/161 (49%), Gaps = 10/161 (6%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR-----KEREK 84
++ +R K + + R R + R RER + + + +K+ R + RERK+ +ER+K
Sbjct: 105 SENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKK 164
Query: 85 QRKERREKERRKRKKEKKKRERKQRGR-RERKKKKERKERERENKQRRERKRKKRRKK-- 141
R RE++RR R + + + + R R R R + + R ++R K RR + R
Sbjct: 165 SRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 224
Query: 142 --KRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180
+ R +E R +R K+ +E+REK+ +K+++
Sbjct: 225 PFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
Score = 66.6 bits (161), Expect = 2e-11
Identities = 35/143 (24%), Positives = 73/143 (51%), Gaps = 12/143 (8%)
Query: 26 SKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
S+ +R R +ER++ R RER+K R R R +++K R R +ER+R+ + R +
Sbjct: 128 SRSRERRHRSRSRERKKSRSRSRERKKSRSRSR-----ERKKSRSRSRERKRRIRSRSRS 182
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE-------RERENKQRRERKRKKR 138
R R + R + + + R+RK+R + R+ + R R + +R
Sbjct: 183 RSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARR 242
Query: 139 RKKKRRKERKREKERGKRERKRK 161
++ ++ + +REKE +++++++
Sbjct: 243 LERAKKLQEQREKEMVEKQKQQE 265
Score = 62.0 bits (149), Expect = 5e-10
Identities = 38/128 (29%), Positives = 63/128 (49%), Gaps = 2/128 (1%)
Query: 21 SCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR- 79
S S K R ERKK R +RK+ R + R+R+R + + + + R R + R R R
Sbjct: 137 SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRT 196
Query: 80 KEREKQRKERREKERR-KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138
+ R + RK+R EK RR R + RGR +E R E ++ + +R+K
Sbjct: 197 RSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKE 256
Query: 139 RKKKRRKE 146
+K++++
Sbjct: 257 MVEKQKQQ 264
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 104 bits (260), Expect = 7e-23
Identities = 68/199 (34%), Positives = 116/199 (58%), Gaps = 14/199 (7%)
Query: 27 KPCTQRESERKKERREREKRK-REREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
KP Q + K R+ EKRK + R + E GK + K K+R E ER+++ RE+Q
Sbjct: 52 KPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKER----EHERRKRHREEQ 107
Query: 86 RKERREKERRKRK---KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK 142
K RRE ER+KR+ +E +RER + + ERK+++ERK RE++ K++RE+K ++RR ++
Sbjct: 108 DKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQ-KEQREQKERERRAEE 166
Query: 143 RRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKK 202
RRKER+ +E R ++ ++ K +R + RER E + +K K+E+ ++
Sbjct: 167 RRKEREARREVSAHHRTMRE-DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 225
Query: 203 KERKKDRK----TDRQTDS 217
++ D + ++R+T S
Sbjct: 226 RDLLSDLQDISDSERKTSS 244
Score = 94.4 bits (233), Expect = 1e-19
Identities = 59/190 (31%), Positives = 106/190 (55%), Gaps = 13/190 (6%)
Query: 26 SKPCTQRESERKKERREREKRKRE-REKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
SK + E E + R E R R ++ +RG+++ K ++ RKE+
Sbjct: 9 SKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIK----PPQQMSRKEKVH 64
Query: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR 144
RK+ + KE+R+ + + G+ R K+KER+ R K+ RE + K RR+ +R+
Sbjct: 65 HRKDEKRKEKRRHRSHSA-----EGGKHARVKEKEREHERR--KRHREEQDKARREWERQ 117
Query: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE 204
K R+ +E +RER R ++ + +RE++R + R+++K++RE+KER R +ER+KER ++E
Sbjct: 118 KRREMAREHSRRERDRLEQLERKRERER-KMREQQKEQREQKERERRAEERRKEREARRE 176
Query: 205 RKKDRKTDRQ 214
+T R+
Sbjct: 177 VSAHHRTMRE 186
Score = 91.3 bits (225), Expect = 8e-19
Identities = 50/202 (24%), Positives = 104/202 (51%), Gaps = 16/202 (7%)
Query: 31 QRESERKKERRE-REKRKREREKERKRERGKKEKKKRKKR----ERGKERERKRKEREKQ 85
+RE ER+K RE ++K +RE E++++RE ++ ++ + R ER +ERERK +E++K+
Sbjct: 94 EREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKE 153
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
++E++E+ERR ++ K++ R++ R +++ ++ + + R R R + +
Sbjct: 154 QREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGD 213
Query: 146 ERKREKERGKRER-----------KRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
RK KE ER +K E + E ++E E +E E
Sbjct: 214 GRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 273
Query: 195 RKKERRKKKERKKDRKTDRQTD 216
+ E +++E +++ +T ++
Sbjct: 274 EESEEEEEEEEEEEEETGSNSE 295
Score = 89.7 bits (221), Expect = 2e-18
Identities = 49/162 (30%), Positives = 90/162 (55%), Gaps = 2/162 (1%)
Query: 40 RREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKK 99
RRE R E + + ++ +++K K+ +RK K R + K R ++K
Sbjct: 34 RREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEK 93
Query: 100 EKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERK 159
E++ ER++R R E+ K + ER++ + RE R++R + ++ ERKRE+ER RE++
Sbjct: 94 ERE-HERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQL-ERKRERERKMREQQ 151
Query: 160 RKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
+++R+++ERE++ E RKER+ RE +E ++ K
Sbjct: 152 KEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVK 193
Score = 89.4 bits (220), Expect = 3e-18
Identities = 65/232 (28%), Positives = 123/232 (53%), Gaps = 25/232 (10%)
Query: 65 KRKKRERGKERERKRK--------EREKQRKERREKERRKRKKEKKKRERKQRGRRERKK 116
KR E G+ R+ + + RE ++R E++ K ++ RK++ + +
Sbjct: 10 KRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDE 69
Query: 117 KKERKERERENKQ---RRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE-KKR 172
K++ K R R + + R ++K R+ +RRK + E+++ +RE +R+KR++ RE +R
Sbjct: 70 KRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRR 129
Query: 173 ERNRKE---RKKERERKERRERK--KERKKERRKKKERKKDRKTDRQTDSQVFRPLRESA 227
ER+R E RK+ERERK R ++K +E+K+ R+ +ER+K+R+ R+ + R +RE
Sbjct: 130 ERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMREDY 188
Query: 228 FNRVTVTGVFR------YRIFHTGLDHFPIKTNILLSRHEVNDGEIEVNDGE 273
++V + R F G P+K + R ++D + +++D E
Sbjct: 189 SDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ-DISDSE 239
Score = 86.7 bits (213), Expect = 2e-17
Identities = 57/215 (26%), Positives = 111/215 (51%), Gaps = 27/215 (12%)
Query: 37 KKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRK 96
K++ RE E+RKR RE++ ++ ++E +++K+RE +E R+ ++R +Q + +RE+ER+
Sbjct: 91 KEKEREHERRKRHREEQ---DKARREWERQKRREMAREHSRRERDRLEQLERKRERERKM 147
Query: 97 RKKEKKKRERKQRGRR------ERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
R+++K++RE+K+R RR ER+ ++E R ++ K K + RE
Sbjct: 148 REQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRE 207
Query: 151 K-ERGKRERKRKKRKKEERE---KKRERNRKERK--------------KERERKERRERK 192
+ E G + K+ K EER+ ++ + ERK E E +E E +
Sbjct: 208 RFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE 267
Query: 193 KERKKERRKKKERKKDRKTDRQTDSQVFRPLRESA 227
+E ++E +++ + + +T S +SA
Sbjct: 268 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 302
Score = 80.1 bits (196), Expect = 2e-15
Identities = 59/212 (27%), Positives = 104/212 (49%), Gaps = 27/212 (12%)
Query: 31 QRESERKKER---REREKRKRER----EKERKRERGKKEKKKRKKRERGKERERKRKERE 83
+RE ER+K R RE +R+R+R E++R+RER +E++K ++ + KERER+ +ER
Sbjct: 111 RREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQ--KERERRAEERR 168
Query: 84 KQRKERRE-----KERRKRKKEKKK------------RERKQRGRRERKKKKERKERERE 126
K+R+ RRE + R+ +K K RER + G RK KE K ER+
Sbjct: 169 KEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG-DGRKPVKEEKMEERD 227
Query: 127 NKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERK 186
+ RK + E G E + ++ ++EE E + +E ++E E +
Sbjct: 228 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEE 287
Query: 187 ERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
E E E+ ++ +++ D + +++
Sbjct: 288 EETGSNSEEASEQSAEEVSEEEMSEDEERENE 319
Score = 63.9 bits (154), Expect = 1e-10
Identities = 43/157 (27%), Positives = 81/157 (51%), Gaps = 15/157 (9%)
Query: 81 EREKQRKERREKERRKRKKE------KKKRERKQRGRRERKKKKERKERERENKQRRERK 134
+R+ +R E E R + E +RE R E K ++ +++ +
Sbjct: 6 DRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHH 65
Query: 135 RKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKER---ERKERRER 191
RK ++K++R+ R E GK R ++K ++ ER R+R+R+E+ K R ER++RRE
Sbjct: 66 RKDEKRKEKRRHRSHSAEGGKHARVKEKEREHER---RKRHREEQDKARREWERQKRREM 122
Query: 192 KKE---RKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
+E R+++R ++ ERK++R+ + + R +E
Sbjct: 123 AREHSRRERDRLEQLERKRERERKMREQQKEQREQKE 159
Score = 42.4 bits (98), Expect = 4e-04
Identities = 41/205 (20%), Positives = 86/205 (41%), Gaps = 51/205 (24%)
Query: 31 QRESERKKERREREKRKRE-REKERKRERGKKEKKKRKK--------------------- 68
+R+ ER+++ RE++K +RE +E+ER+ E +KE++ R++
Sbjct: 138 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 197
Query: 69 --------RER-----GKE--RERKRKERE----------KQRK----ERREKERRKRKK 99
RER G++ +E K +ER+ +RK E E +
Sbjct: 198 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 257
Query: 100 EKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERK 159
E+++ E ++ ++ E +E E E ++ + ++ +E E+ ER+
Sbjct: 258 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 317
Query: 160 RKKRKKEEREKKRERNRKERKKERE 184
+ E + +R+ E ++ E
Sbjct: 318 NENHLLVVPESRFDRDSGESEEAEE 342
Score = 35.0 bits (79), Expect = 0.071
Identities = 24/128 (18%), Positives = 55/128 (42%), Gaps = 5/128 (3%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
+ E+ +ER + + ERK + + +E E + +E E E E+
Sbjct: 219 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 278
Query: 93 ERRKRKKEKKK-----RERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKER 147
E + ++E+++ E ++ E +++ ++ EREN+ + R + +
Sbjct: 279 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 338
Query: 148 KREKERGK 155
+ E+E G+
Sbjct: 339 EAEEEVGE 346
Score = 32.7 bits (73), Expect = 0.35
Identities = 24/119 (20%), Positives = 49/119 (41%), Gaps = 5/119 (4%)
Query: 13 LNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERG 72
L ++LQ +S S + S E E+ + E E+E + E+++ ++ E
Sbjct: 228 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEE 287
Query: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRER-----KQRGRRERKKKKERKERERE 126
+E +E +Q E +E +E++ + R R+ + +E +E E
Sbjct: 288 EETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 346
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 104 bits (260), Expect = 7e-23
Identities = 68/199 (34%), Positives = 116/199 (58%), Gaps = 14/199 (7%)
Query: 27 KPCTQRESERKKERREREKRK-REREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
KP Q + K R+ EKRK + R + E GK + K K+R E ER+++ RE+Q
Sbjct: 86 KPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKER----EHERRKRHREEQ 141
Query: 86 RKERREKERRKRK---KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK 142
K RRE ER+KR+ +E +RER + + ERK+++ERK RE++ K++RE+K ++RR ++
Sbjct: 142 DKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQ-KEQREQKERERRAEE 200
Query: 143 RRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKK 202
RRKER+ +E R ++ ++ K +R + RER E + +K K+E+ ++
Sbjct: 201 RRKEREARREVSAHHRTMRE-DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 259
Query: 203 KERKKDRK----TDRQTDS 217
++ D + ++R+T S
Sbjct: 260 RDLLSDLQDISDSERKTSS 278
Score = 98.2 bits (243), Expect = 7e-21
Identities = 72/258 (27%), Positives = 141/258 (54%), Gaps = 27/258 (10%)
Query: 41 REREKRKREREK-ERKRERGKKEK-KKRKKRERGKERERKRK--------EREKQRKERR 90
+E+++RK + EK E KR + ++ KR E G+ R+ + + RE ++R
Sbjct: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ---RRERKRKKRRKKKRRKER 147
E++ K ++ RK++ + +K++ K R R + + R ++K R+ +RRK
Sbjct: 78 EEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRH 137
Query: 148 KREKERGKRERKRKKRKKEERE-KKRERNRKE---RKKERERKERRERKKERKKERRKKK 203
+ E+++ +RE +R+KR++ RE +RER+R E RK+ERERK R ++K++R+++ R+++
Sbjct: 138 REEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERR 197
Query: 204 --ERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVFR------YRIFHTGLDHFPIKTNI 255
ER+K+R+ R+ + R +RE ++V + R F G P+K
Sbjct: 198 AEERRKEREARREVSAH-HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEK 256
Query: 256 LLSRHEVNDGEIEVNDGE 273
+ R ++D + +++D E
Sbjct: 257 MEERDLLSDLQ-DISDSE 273
Score = 96.3 bits (238), Expect = 3e-20
Identities = 63/207 (30%), Positives = 113/207 (54%), Gaps = 28/207 (13%)
Query: 32 RESERKKERREREKRKRER---EKERKRE----------------RGKKEKKKRKKRERG 72
+E +R+KE+ E+ + KR + +++ KR+ R +++ +RG
Sbjct: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
Query: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRERKQR----GRRERKKKKERKERERENK 128
+E + + +Q + + RK +K K+KR + G+ R K+KER+ R K
Sbjct: 78 EEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERR--K 135
Query: 129 QRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKE-RERKE 187
+ RE + K RR+ +R+K R+ +E +RER R ++ ER+++RER +E++KE RE+KE
Sbjct: 136 RHREEQDKARREWERQKRREMAREHSRRERDRLEQL--ERKRERERKMREQQKEQREQKE 193
Query: 188 RRERKKERKKERRKKKERKKDRKTDRQ 214
R R +ER+KER ++E +T R+
Sbjct: 194 RERRAEERRKEREARREVSAHHRTMRE 220
Score = 91.3 bits (225), Expect = 8e-19
Identities = 50/202 (24%), Positives = 104/202 (51%), Gaps = 16/202 (7%)
Query: 31 QRESERKKERRE-REKRKREREKERKRERGKKEKKKRKKR----ERGKERERKRKEREKQ 85
+RE ER+K RE ++K +RE E++++RE ++ ++ + R ER +ERERK +E++K+
Sbjct: 128 EREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKE 187
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
++E++E+ERR ++ K++ R++ R +++ ++ + + R R R + +
Sbjct: 188 QREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGD 247
Query: 146 ERKREKERGKRER-----------KRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
RK KE ER +K E + E ++E E +E E
Sbjct: 248 GRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 307
Query: 195 RKKERRKKKERKKDRKTDRQTD 216
+ E +++E +++ +T ++
Sbjct: 308 EESEEEEEEEEEEEEETGSNSE 329
Score = 86.7 bits (213), Expect = 2e-17
Identities = 57/215 (26%), Positives = 111/215 (51%), Gaps = 27/215 (12%)
Query: 37 KKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRK 96
K++ RE E+RKR RE++ ++ ++E +++K+RE +E R+ ++R +Q + +RE+ER+
Sbjct: 125 KEKEREHERRKRHREEQ---DKARREWERQKRREMAREHSRRERDRLEQLERKRERERKM 181
Query: 97 RKKEKKKRERKQRGRR------ERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
R+++K++RE+K+R RR ER+ ++E R ++ K K + RE
Sbjct: 182 REQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRE 241
Query: 151 K-ERGKRERKRKKRKKEERE---KKRERNRKERK--------------KERERKERRERK 192
+ E G + K+ K EER+ ++ + ERK E E +E E +
Sbjct: 242 RFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE 301
Query: 193 KERKKERRKKKERKKDRKTDRQTDSQVFRPLRESA 227
+E ++E +++ + + +T S +SA
Sbjct: 302 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 336
Score = 82.0 bits (201), Expect = 5e-16
Identities = 56/168 (33%), Positives = 92/168 (54%), Gaps = 14/168 (8%)
Query: 40 RREREKRKREREKER-----KRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKER 94
RRE R E + ++ +KEK +K E+ KE+ R R + K R KE+
Sbjct: 68 RREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEK 127
Query: 95 -RKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153
R+ ++ K+ RE + + RRE +++K R+E RE+ RRER R ++ ++KR +ERK +E+
Sbjct: 128 EREHERRKRHREEQDKARREWERQK-RREMAREHS-RRERDRLEQLERKRERERKM-REQ 184
Query: 154 GKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
K +R++K ERE++ E RKER+ RE +E ++ K
Sbjct: 185 QKEQREQK-----ERERRAEERRKEREARREVSAHHRTMREDYSDKVK 227
Score = 80.1 bits (196), Expect = 2e-15
Identities = 59/212 (27%), Positives = 104/212 (49%), Gaps = 27/212 (12%)
Query: 31 QRESERKKER---REREKRKRER----EKERKRERGKKEKKKRKKRERGKERERKRKERE 83
+RE ER+K R RE +R+R+R E++R+RER +E++K ++ + KERER+ +ER
Sbjct: 145 RREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQ--KERERRAEERR 202
Query: 84 KQRKERRE-----KERRKRKKEKKK------------RERKQRGRRERKKKKERKERERE 126
K+R+ RRE + R+ +K K RER + G RK KE K ER+
Sbjct: 203 KEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG-DGRKPVKEEKMEERD 261
Query: 127 NKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERK 186
+ RK + E G E + ++ ++EE E + +E ++E E +
Sbjct: 262 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEE 321
Query: 187 ERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
E E E+ ++ +++ D + +++
Sbjct: 322 EETGSNSEEASEQSAEEVSEEEMSEDEERENE 353
Score = 42.4 bits (98), Expect = 4e-04
Identities = 41/205 (20%), Positives = 86/205 (41%), Gaps = 51/205 (24%)
Query: 31 QRESERKKERREREKRKRE-REKERKRERGKKEKKKRKK--------------------- 68
+R+ ER+++ RE++K +RE +E+ER+ E +KE++ R++
Sbjct: 172 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 231
Query: 69 --------RER-----GKE--RERKRKERE----------KQRK----ERREKERRKRKK 99
RER G++ +E K +ER+ +RK E E +
Sbjct: 232 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 291
Query: 100 EKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERK 159
E+++ E ++ ++ E +E E E ++ + ++ +E E+ ER+
Sbjct: 292 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 351
Query: 160 RKKRKKEEREKKRERNRKERKKERE 184
+ E + +R+ E ++ E
Sbjct: 352 NENHLLVVPESRFDRDSGESEEAEE 376
Score = 35.0 bits (79), Expect = 0.071
Identities = 24/128 (18%), Positives = 55/128 (42%), Gaps = 5/128 (3%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
+ E+ +ER + + ERK + + +E E + +E E E E+
Sbjct: 253 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 312
Query: 93 ERRKRKKEKKK-----RERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKER 147
E + ++E+++ E ++ E +++ ++ EREN+ + R + +
Sbjct: 313 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 372
Query: 148 KREKERGK 155
+ E+E G+
Sbjct: 373 EAEEEVGE 380
Score = 32.7 bits (73), Expect = 0.35
Identities = 24/119 (20%), Positives = 49/119 (41%), Gaps = 5/119 (4%)
Query: 13 LNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERG 72
L ++LQ +S S + S E E+ + E E+E + E+++ ++ E
Sbjct: 262 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEE 321
Query: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRER-----KQRGRRERKKKKERKERERE 126
+E +E +Q E +E +E++ + R R+ + +E +E E
Sbjct: 322 EETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 380
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 104 bits (259), Expect = 1e-22
Identities = 62/196 (31%), Positives = 116/196 (59%), Gaps = 5/196 (2%)
Query: 34 SERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93
+++K E++ERE++KR+ EK + R+ +KE+ + K+++ K++E +RK E+ K + +
Sbjct: 229 AQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVD 288
Query: 94 RR--KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151
+EK + E KKK+ K++++ K+ +E+++KK K K +
Sbjct: 289 TGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEAL 348
Query: 152 ERGKRERKRKKRKKEEREKK-RERNRKERKKERERKERRERKKERKKER--RKKKERKKD 208
+ K E +R+KR++EER K+ E K +++ER +E+RERKK+++KER R KKE K
Sbjct: 349 AKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLL 408
Query: 209 RKTDRQTDSQVFRPLR 224
K+ R+ ++ L+
Sbjct: 409 TKSQREARARAEATLK 424
Score = 73.9 bits (180), Expect = 1e-13
Identities = 42/163 (25%), Positives = 89/163 (54%), Gaps = 2/163 (1%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
T E + + ++++++K+K++ EKE K + KK K + + + ++E E+Q++E
Sbjct: 303 TAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREE 362
Query: 90 REKERRKRKKEKKKRE--RKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKER 147
E+ +R + E K++E R ++ +RERKK+KE++ +ER K+ + + +R + R +
Sbjct: 363 EERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEAT 422
Query: 148 KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRE 190
+ + E K ++R ++ RK+ ++ E KE E
Sbjct: 423 LKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSE 465
Score = 68.6 bits (166), Expect = 6e-12
Identities = 52/223 (23%), Positives = 101/223 (45%), Gaps = 25/223 (11%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
RE+ K E+ ++K++K ++GKK+ E ++++ K K+ K + E
Sbjct: 76 RETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYS 135
Query: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR---------------- 135
K ++ K + ++ KK +E E +K+ +ER R
Sbjct: 136 GSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQ 195
Query: 136 -KKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
+K +KK ++ + E G + + K +KK E+ +ERKK E K + + KE
Sbjct: 196 SRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKE 255
Query: 195 RKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTV-TGV 236
+++ KK++ K +++ R+ + E+ ++VTV TGV
Sbjct: 256 KEELETGKKDQSKQKESQRKFE-------EETVKSKVTVDTGV 291
Score = 63.2 bits (152), Expect = 2e-10
Identities = 57/237 (24%), Positives = 115/237 (48%), Gaps = 49/237 (20%)
Query: 31 QRESERKKERREREKRK---------------REREKERKRERGKKEKKKRKKRERGKER 75
+++ + +KE +E+EK+K + +E+E +++R ++E+ KR + K +
Sbjct: 318 KKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRK 377
Query: 76 ERKRKEREK-QRKERREKERRKR-KKEKK---KRERKQRGRRERKKK------KERKERE 124
E +R E+EK +RK+++EKER++R KKE K K +R+ R R E K E ++
Sbjct: 378 EEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKD 437
Query: 125 RENKQRRERKRKKRRKKKRRKERKREK------------ERGKRERKRKKRKKEEREKKR 172
K+R + KKR+K ++ E K E+G E++ E E++
Sbjct: 438 SLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEED 497
Query: 173 ERNR-----------KERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
+ +E +K K E K+ ++E +++E ++D +++ + + +
Sbjct: 498 TEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEE 554
Score = 52.8 bits (125), Expect = 3e-07
Identities = 57/266 (21%), Positives = 108/266 (40%), Gaps = 76/266 (28%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR----- 86
+E E +++R E E+ KR E E KR+ ++E+ +++KRER K++E++RKER K+
Sbjct: 352 KEEEERQKREEEERIKRLEELEAKRK--EEERLEQEKRERKKQKEKERKERLKKEGKLLT 409
Query: 87 -------------------------------KERREKERRKRKKEKKKRERKQ------- 108
K+R E +KRKK ++ E K+
Sbjct: 410 KSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMEL 469
Query: 109 --------RGRRERKKKKERKERERE----------------NKQRRERKRKKRRKKKRR 144
+G E+++ E E E +++ + + K + +
Sbjct: 470 CAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKE 529
Query: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE 204
+ E+E + E + ++EE E + E + + + E+ E+ K KK
Sbjct: 530 NPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKP------ 583
Query: 205 RKKDRKTDRQTDSQVFRPLRESAFNR 230
K+ +D + DS R E A+++
Sbjct: 584 -SKEMSSDSEYDSDDDRTKEERAYDK 608
Score = 40.4 bits (93), Expect = 0.002
Identities = 60/289 (20%), Positives = 112/289 (38%), Gaps = 78/289 (26%)
Query: 2 VKAISSRAA-VKLNTELQMVSCSHISKPCTQRESERKKERR-EREKRKREREKERKR-ER 58
VKA+ A +K E Q K + E++RK+E R E+EKR+R+++KE++R ER
Sbjct: 341 VKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKER 400
Query: 59 GKKE-----KKKRKKRERGKE-------------------------RERKRKEREKQRKE 88
KKE K +R+ R R + ++KRK+ +Q +
Sbjct: 401 LKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLES 460
Query: 89 RR-------------------EKERRKRKKEKKKRE-------------------RKQRG 110
+ EKE E ++ E K G
Sbjct: 461 KEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEG 520
Query: 111 RR------ERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRK 164
+ E +++E +E E E + E + ++ + + E E E+ E+ K
Sbjct: 521 NKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESE-GSEGDEEDEKVSDEKDSGKTL 579
Query: 165 KEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDR 213
++ K+ + + + KE R K +++ +++ E K+ T++
Sbjct: 580 DKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEK 628
Score = 39.7 bits (91), Expect = 0.003
Identities = 24/111 (21%), Positives = 48/111 (43%), Gaps = 6/111 (5%)
Query: 39 ERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRK 98
E +E + + E E+E + + +E+++ + G E + E+ K EK+ K
Sbjct: 526 EVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGD------EEDEKVSDEKDSGKTL 579
Query: 99 KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
+K +E + + ++ER + +RR KR+ K E+ R
Sbjct: 580 DKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLR 630
Score = 38.1 bits (87), Expect = 0.008
Identities = 25/107 (23%), Positives = 47/107 (43%), Gaps = 5/107 (4%)
Query: 24 HISKPCTQRESERKKERREREKRKREREKERKRERG----KKEKKKRKKRERGKERERK- 78
HI E E ++E E ++ E E+E G ++++K +++ GK ++K
Sbjct: 524 HIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKP 583
Query: 79 RKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERER 125
KE + + +R K ++ K +R+ RR K E+ R
Sbjct: 584 SKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLR 630
Score = 35.0 bits (79), Expect = 0.071
Identities = 29/171 (16%), Positives = 74/171 (43%), Gaps = 11/171 (6%)
Query: 59 GKKEKKKRKKRER--------GKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRG 110
GKK+K K + + E E +E++ ++ + K+++++KK+ + +
Sbjct: 2 GKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKE 61
Query: 111 RRERKKKKERKEREREN---KQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEE 167
E + + + +RE K + + K K++K +K +K+ + K+
Sbjct: 62 LEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDS 121
Query: 168 REKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
+ KK + + E + + + ++ K + +K +K D + + +S+
Sbjct: 122 KSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSK 172
Score = 34.7 bits (78), Expect = 0.093
Identities = 25/114 (21%), Positives = 51/114 (44%), Gaps = 12/114 (10%)
Query: 77 RKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK 136
++ E E++ +E E++ E+ + E ++ G E + E E+ + E+
Sbjct: 528 KENPEEEEEEEEEEEED------EESEEEEEEEGESEGSEGDEEDEKVSD-----EKDSG 576
Query: 137 KRRKKKRRKERKREKERGKRERKRKKRKKEEREKKR-ERNRKERKKERERKERR 189
K KK KE + E + + K+ + ++ K+R E+ R E K ++ R
Sbjct: 577 KTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLR 630
Score = 31.2 bits (69), Expect = 1.0
Identities = 20/99 (20%), Positives = 46/99 (46%)
Query: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180
KE+E + + +++K KK++ K +E + K ++ K E N +E
Sbjct: 33 KEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFT 92
Query: 181 KERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQV 219
+ ++K+ ++ KK+ + ++ KD K+ + +V
Sbjct: 93 SKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKV 131
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 103 bits (258), Expect = 1e-22
Identities = 51/187 (27%), Positives = 97/187 (51%), Gaps = 3/187 (1%)
Query: 42 EREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEK 101
E +K++ +R R R R ++ + R R +R+ K R RR K R+R+
Sbjct: 238 EPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHS 297
Query: 102 KKRERKQRGR-RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERK- 159
++R R+ R + R KKKE KE++R + +R + R+ R+R G R K
Sbjct: 298 RERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKK 357
Query: 160 -RKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
R ++K R R++KE+KK+++++ R+ ++ +++K K+++KDR+ ++D
Sbjct: 358 PRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKD 417
Query: 219 VFRPLRE 225
V + R+
Sbjct: 418 VKQVTRD 424
Score = 101 bits (251), Expect = 8e-22
Identities = 54/205 (26%), Positives = 103/205 (50%), Gaps = 6/205 (2%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
+R R + R + R R R K +R R ++ R+ R K R++K++++EK+R +
Sbjct: 267 RRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTP 326
Query: 91 EKE----RRKRKKEKKKRERKQRG--RRERKKKKERKERERENKQRRERKRKKRRKKKRR 144
K RR R +++R R+ R R +K + +++ R RR +K KK+ K K R
Sbjct: 327 PKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKER 386
Query: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE 204
+RE+ K+++ + K K ER+ + +++ K+ ++ + +E+ ++ KKE +K E
Sbjct: 387 SRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIE 446
Query: 205 RKKDRKTDRQTDSQVFRPLRESAFN 229
+ + + LRES N
Sbjct: 447 TGSPKTKECSVEKGTGDSLRESKVN 471
Score = 100 bits (250), Expect = 1e-21
Identities = 58/184 (31%), Positives = 97/184 (52%), Gaps = 15/184 (8%)
Query: 37 KKERREREKRKREREKERKR---ERGKKEKKKRKKRERGKERERKR-KEREKQRKERREK 92
KKE + R R R R + R+ R ++ + + ++R K R R+R K ++R RE+
Sbjct: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300
Query: 93 ERRKRKKEK---KKRERKQRGRRERKKKK---ERKERERENKQRRERKRKKRRKKKRRKE 146
RR R K KK+E K++ R + K R+ R ++RR R R R K+ +
Sbjct: 301 GRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRS 360
Query: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
KR+ R R+ KK KK++++K+R R+ +ER +++K K+++K+R +K E
Sbjct: 361 PKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKK-----SKDKEKDRERKSESD 415
Query: 207 KDRK 210
KD K
Sbjct: 416 KDVK 419
Score = 85.9 bits (211), Expect = 4e-17
Identities = 56/184 (30%), Positives = 86/184 (46%), Gaps = 29/184 (15%)
Query: 61 KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER 120
K K+ E +R R+ + E +KE ++R + R R+ RR + R
Sbjct: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRR---RRTPSSSRHR 267
Query: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRER---KRKKRKKEEREKKRERN-- 175
+ R R ++ + R +RR K R+ R +ERG+R R K + +KKE++EKKR +
Sbjct: 268 RSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPP 327
Query: 176 ------RKERKKERERKERRER------KKERKKE---------RRKKKERKKDRKTDRQ 214
R+ R RER+ RR R KK R + RR KKE+KKD+ +R
Sbjct: 328 KSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERS 387
Query: 215 TDSQ 218
D +
Sbjct: 388 RDER 391
Score = 71.2 bits (173), Expect = 9e-13
Identities = 57/204 (27%), Positives = 94/204 (46%), Gaps = 21/204 (10%)
Query: 7 SRAAVKLNTELQMVSCSHISKPCTQRESERKKERRER------EKRKREREKERKRERGK 60
SR+ + + + S P +R R++ RR R +K+K ++EK+R + K
Sbjct: 269 SRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPK 328
Query: 61 KEKKKRKKRERGKERERKR---------KEREKQRKERREKERRKRKKEK---KKRERKQ 108
R+ R +ER R+R K R +RK R R+ KKEK K +ER
Sbjct: 329 SYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKER-S 387
Query: 109 RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEER 168
R RER K++K +++E + RERK + + K+ E+E+G K KK +K+
Sbjct: 388 RDERERSTSKKKKSKDKE--KDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPI 445
Query: 169 EKKRERNRKERKKERERKERRERK 192
E + ++ ++ RE K
Sbjct: 446 ETGSPKTKECSVEKGTGDSLRESK 469
Score = 47.4 bits (111), Expect = 1e-05
Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 2/106 (1%)
Query: 24 HISKPCTQRESERKKERRERE--KRKREREKERKRERGKKEKKKRKKRERGKERERKRKE 81
H + ++ ER ++ RER K+K+ ++KE+ RER + K K+ R + E + +
Sbjct: 374 HKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYD 433
Query: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKEREREN 127
EK++KE ++ K K+ K G R+ K + E+
Sbjct: 434 SEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEED 479
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 103 bits (256), Expect = 2e-22
Identities = 59/191 (30%), Positives = 104/191 (54%), Gaps = 15/191 (7%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
R K+ +R ++R R R+++R+RER + + K+R R ++R+R R+ R ++R RE
Sbjct: 25 RSPSDKRSKRGDDRRSRSRDRDRRRER---SRSRDKRRSRSRDRKRLRRSRSRERDRSRE 81
Query: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK------RKKRRKKKRRK 145
+ RR R +++++ + RGRR R K ++ EN+ R + K K+++K K K
Sbjct: 82 R-RRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDK 140
Query: 146 ERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKER 205
E ++EK+ G + + K E E ++ + R E+ +E +RK+ E E KKE + K+
Sbjct: 141 EDEKEKDAGNFD-----QNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQG 195
Query: 206 KKDRKTDRQTD 216
KK D D
Sbjct: 196 KKWSLEDDDDD 206
Score = 101 bits (251), Expect = 8e-22
Identities = 50/175 (28%), Positives = 95/175 (54%), Gaps = 12/175 (6%)
Query: 40 RREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKK 99
R R RKR + R R + K+ +RG +R + ++R+++R+ R +++R+ +
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62
Query: 100 EKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR---------KKKRRKERKRE 150
+KR R+ R R + ++ R+ R R+ ++ R R R +R KK + R +E
Sbjct: 63 RDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE 122
Query: 151 KERGKRERKRKKRKKEEREKKRER---NRKERKKERERKERRERKKERKKERRKK 202
K G K KK+ K+++E ++E+ N + K E E ++R+ER ++ ++E+RKK
Sbjct: 123 KTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKK 177
Score = 82.8 bits (203), Expect = 3e-16
Identities = 44/164 (26%), Positives = 87/164 (53%), Gaps = 13/164 (7%)
Query: 59 GKKEKKKRKKR-ERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKK 117
G++ + RK+ RG+ R R ++ +R +RR R +++ +R + R R +R+ +
Sbjct: 2 GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61
Query: 118 KERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKR------KKRKKEEREKK 171
++R R ++ R ER R + R++ R ++R+R + R + R R K +K E R +
Sbjct: 62 SRDRKRLRRSRSR-ERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRS 120
Query: 172 RER-----NRKERKKERERKERRERKKERKKERRKKKERKKDRK 210
+E+ + KE+KK+++ KE + K ++ K +E + RK
Sbjct: 121 KEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRK 164
Score = 74.7 bits (182), Expect = 8e-14
Identities = 44/171 (25%), Positives = 85/171 (49%), Gaps = 9/171 (5%)
Query: 32 RESERKKERREREKRKREREK---ERKRERGKKEKKKRKKRERGKERERKRKEREKQRKE 88
R ER + R +R R R+R++ R RER + +++R+ R R + R R R + R
Sbjct: 47 RRRERSRSRDKRRSRSRDRKRLRRSRSRERDRS-RERRRSRSRDRRRSRSRSRGRRSRSS 105
Query: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ-----RRERKRKKRRKKKR 143
+ +K + + +E+ G ++KKK++ ++E E ++ + + ++ RK+K
Sbjct: 106 SPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKE 165
Query: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
R E+ RE++R K + KKE E K+ + + + + E +KE
Sbjct: 166 RVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKE 216
Score = 72.0 bits (175), Expect = 5e-13
Identities = 47/173 (27%), Positives = 79/173 (45%), Gaps = 5/173 (2%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
R ER + R R R R+R + R R RG++ + + K+ E + + +EK
Sbjct: 72 RSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSS-SPGNKSKKTENRSRSKEKTDGGESS 130
Query: 92 KERRKRKKEKKKRERKQRGRRERKKKKE--RKERERENKQRRERKRKKRRKKKRRKERKR 149
KE++K K +K+ + K G ++ K +E RK +ER K R E+++K K+
Sbjct: 131 KEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIE 190
Query: 150 EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKK 202
E ++GK+ E+ + E+ E E E + + E KE KK
Sbjct: 191 EMKQGKKWSLEDDDDDEDDPAEAEKEGNE--MEGEELDPLDAYMEEVKEEVKK 241
Score = 59.3 bits (142), Expect = 4e-09
Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 9/118 (7%)
Query: 110 GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKR-ERKRKKRKKEER 168
GR R +K R R + R R +R K+ R R ++R +R ER R + K+ R
Sbjct: 2 GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61
Query: 169 EKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRES 226
+ R+R R+ R +ER+R R++ R + ++R++ R R S+ P +S
Sbjct: 62 SRDRKRLRRSRSRERDRS--------RERRRSRSRDRRRSRSRSRGRRSRSSSPGNKS 111
Score = 50.1 bits (118), Expect = 2e-06
Identities = 41/155 (26%), Positives = 73/155 (47%), Gaps = 21/155 (13%)
Query: 26 SKPCTQRESERKKERREREKRKR---EREKERKRERGKKEKKKRK-----KRERGKERER 77
S+ + +K E R R K K E KE+K+++ KE +K K + + +E R
Sbjct: 102 SRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMR 161
Query: 78 KRKER-EKQRKERREKERRKRKKEKKKRERKQRGRR------------ERKKKKERKERE 124
KRKER EK R+E+R+K + KK+ E ++G++ + +KE E E
Sbjct: 162 KRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEME 221
Query: 125 RENKQRRERKRKKRRKKKRRKERKREKERGKRERK 159
E + ++ +++ ++ + K G E+K
Sbjct: 222 GEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKK 256
Score = 38.5 bits (88), Expect = 0.006
Identities = 21/90 (23%), Positives = 41/90 (45%), Gaps = 14/90 (15%)
Query: 141 KKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERR 200
++ R RKR RG+ + + R ++ KR +R+ R ++R+R R
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDR--------------R 48
Query: 201 KKKERKKDRKTDRQTDSQVFRPLRESAFNR 230
+++ R +D++ R D + R R +R
Sbjct: 49 RERSRSRDKRRSRSRDRKRLRRSRSRERDR 78
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 102 bits (253), Expect = 5e-22
Identities = 58/197 (29%), Positives = 125/197 (63%), Gaps = 11/197 (5%)
Query: 31 QRESERKKERREREKRKREREKERKRERG---KKEKKKRKKRERGKERERKRKEREKQRK 87
++ E++++ RE+E++ RE+E++ +R+ +KE+K R++ E E+E K + +E+
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 373
Query: 88 ERREKERRKR----KKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKR 143
E+ EK RR+ +KE+K RE +++ + K +++ ++R+ E K R + KR+++ K
Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 433
Query: 144 RKERK-REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKE---R 199
R+E K RE+E RE+++K ++EE+ ++E+ R+E K++ + + R+ +K ++E R
Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR 493
Query: 200 RKKKERKKDRKTDRQTD 216
+K+K +++ K +Q +
Sbjct: 494 QKEKMHEQEEKIRKQEE 510
Score = 97.4 bits (241), Expect = 1e-20
Identities = 58/194 (29%), Positives = 122/194 (62%), Gaps = 8/194 (4%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ--RKE 88
++ E++K R + EKR+ E + + +R ++E K ++ E+ +E+E K +E+EK+ R+E
Sbjct: 398 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 457
Query: 89 RREKERRKRKKEKKKRERKQRGRRERK-KKKERKERERENKQRRERK-RKKRRKKKRRKE 146
+ E+ K ++E+K++E+++ R+E K ++E R++E +E K RK+ K R++E
Sbjct: 458 EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE 517
Query: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERER----KERRERKKERKKERRKK 202
+ RE+E RE++ K ++EE+ +++E +E +K E+ +E + +++E K R+++
Sbjct: 518 KIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEE 577
Query: 203 KERKKDRKTDRQTD 216
K R+++ K RQ +
Sbjct: 578 KIREQEEKVWRQEE 591
Score = 94.0 bits (232), Expect = 1e-19
Identities = 61/221 (27%), Positives = 126/221 (57%), Gaps = 17/221 (7%)
Query: 13 LNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERG--KKEKKKRKKRE 70
L ELQ VS + + E + +++ EK R+ EK ++ E ++E+K R++ E
Sbjct: 270 LGKELQSVSAK-LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328
Query: 71 RGKERERKRKEREKQRKERREKERRK-----RKKEKKKR--------ERKQRGRRERKKK 117
+ +E+E K + +E+ E+ EK RR+ K+EK +R E K R + E +
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 388
Query: 118 KERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRK 177
KE K RE E K + K +++ +K++ +E+ RE+E+ ++E++ K ++EE+ +++E +
Sbjct: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK-RQEQEAKMWRQEEKIREQEEKIR 447
Query: 178 ERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
E++K+ R+E + ++E+ +E K++E+++ + + + Q
Sbjct: 448 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQ 488
Score = 94.0 bits (232), Expect = 1e-19
Identities = 54/189 (28%), Positives = 119/189 (62%), Gaps = 6/189 (3%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
R+ E+ +E E+ + + E+ +E++ + ++E+K R++ E E+E K + +E+ E+ E
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363
Query: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151
K RR+ + +K E K R + E +KE K RE E K + K +++ +K++ +E+ RE+
Sbjct: 364 KMRRQEEMMWEKEE-KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 422
Query: 152 ERGKRERKRKKRKKEEREKKRERNRKERKKERERKERR--ERKKERKKERRKKKER--KK 207
E+ ++E++ K ++EE+ +++E +E++K+ R+E + E++K R++E+R+++E ++
Sbjct: 423 EK-RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 481
Query: 208 DRKTDRQTD 216
+ K Q +
Sbjct: 482 EEKIHEQEE 490
Score = 94.0 bits (232), Expect = 1e-19
Identities = 51/194 (26%), Positives = 123/194 (63%), Gaps = 9/194 (4%)
Query: 32 RESERKKERR-----EREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
RE E+K R+ E+EK + E +++ + E ++E+K ++ E +++E+ ++ EK R
Sbjct: 447 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIR 506
Query: 87 KERRE---KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKR 143
K+ + +E + R++E+K RE++++ R+ +K +E++E RE ++ E+++ +K++
Sbjct: 507 KQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ 566
Query: 144 RKERKREKERGK-RERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKK 202
+E K ++ K RE++ K ++EE+ +++E R+E++++ ++E + R++E K + +++
Sbjct: 567 EQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEE 626
Query: 203 KERKKDRKTDRQTD 216
K R+++ K Q +
Sbjct: 627 KIREQEEKIREQEE 640
Score = 93.6 bits (231), Expect = 2e-19
Identities = 54/176 (30%), Positives = 110/176 (62%), Gaps = 5/176 (2%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Q E +KE + RE ++ E+E+ RE+ +K +++ K RE+ K +E++ K +Q ++ R
Sbjct: 382 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK-MWRQEEKIR 440
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
E+E + R++EKK ++++ + K ++E K +E+E R+E K ++ + R+KE+ E
Sbjct: 441 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHE 500
Query: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
+E E+ RK+ +K R++++ R ++E+ +E+E K R+ +K R++E ++E K
Sbjct: 501 QE----EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552
Score = 92.8 bits (229), Expect = 3e-19
Identities = 53/192 (27%), Positives = 121/192 (63%), Gaps = 13/192 (6%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKER---------ERKRKE 81
+ E R++E+R+ ++ K R++E+ RE+ +K +++ KK R +E+ E KR+E
Sbjct: 415 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 474
Query: 82 RE---KQRKERREKERRKRKKEKK-KRERKQRGRRERKKKKERKERERENKQRRERKRKK 137
+E +Q ++ E+E R+KEK ++E K R + E+ ++E K RE+E K R + ++
Sbjct: 475 QEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534
Query: 138 RRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKK 197
R+++K R++ + +E K + K ++E+R+++ ++ ++ +K RE++E+ R++E+ +
Sbjct: 535 RQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR 594
Query: 198 ERRKKKERKKDR 209
E+ +K++ ++++
Sbjct: 595 EQEEKRQEQEEK 606
Score = 92.4 bits (228), Expect = 4e-19
Identities = 50/186 (26%), Positives = 121/186 (65%), Gaps = 11/186 (5%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
E E+++E+ ++ R+ E+ +E++ + ++E+K R++ E+ +E+E K ++E++ +E+ EK
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEK 620
Query: 93 ----ERRKRKKEKKKRERKQRGRRERKKKKERKER--ERENKQRRERKRKKRRKKKRRKE 146
E + R++E+K RE+++ + + +K E++E+ E+E K + + + R+++K R++
Sbjct: 621 IQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQ 680
Query: 147 RKREKERGKRERKRKKRKKEEREKKRERNRK-----ERKKERERKERRERKKERKKERRK 201
K+ +E+ ++ R++++ +E+ EK E+ K E+ +E+E K RR+ +K ++E R
Sbjct: 681 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 740
Query: 202 KKERKK 207
+++ +K
Sbjct: 741 RQQEEK 746
Score = 92.0 bits (227), Expect = 5e-19
Identities = 60/203 (29%), Positives = 126/203 (62%), Gaps = 17/203 (8%)
Query: 31 QRESERKKERREREKRKREREKERKRERG--KKEKKKRKKRERGKERERK---RKEREKQ 85
Q + ++E+R+ E++ RE+EK +++E ++E+K R++ E+ +E+E+K ++E+ +
Sbjct: 403 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE 462
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRE--RKKKKERKERERENKQ-----RRERKRKKR 138
+++ RE+E+R+ ++E ++E K + E R+K+K ++ E+ KQ R+E K +++
Sbjct: 463 QEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQ 522
Query: 139 RKKKRRKE----RKREKERGKRERKRKKRKKEEREK-KRERNRKERKKERERKERRERKK 193
+K R +E R+ EK R + E R++ K E+EK E R+E++ + R+E + R++
Sbjct: 523 EEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ 582
Query: 194 ERKKERRKKKERKKDRKTDRQTD 216
E K R+++K R+++ K Q +
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEE 605
Score = 91.7 bits (226), Expect = 6e-19
Identities = 54/209 (25%), Positives = 126/209 (60%), Gaps = 16/209 (7%)
Query: 26 SKPCTQRESERKKERREREKRK---REREKERKRERGKKEKKKRKKRERGKERER----- 77
+K Q E R++E + RE+ K R+ EK ++E+ ++E+K++++ E ++ E+
Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE 489
Query: 78 -----KRKEREKQRKERREKERRKRKKEK-KKRERKQRGRRERKKKKERKERERENKQRR 131
K K E++ K R+++E+ R++EK +++E K R + E+ ++E K RE+E R
Sbjct: 490 EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE 549
Query: 132 ERKRKKRRK--KKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERR 189
E K ++ K ++ +++ + +K + E+ R++ +K R++++ R ++E+++E+E K +
Sbjct: 550 EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK 609
Query: 190 ERKKERKKERRKKKERKKDRKTDRQTDSQ 218
+ +K R++E + +++ +K R+ + + Q
Sbjct: 610 QEEKIREQEEKIQEQEEKIREQEEKIREQ 638
Score = 91.7 bits (226), Expect = 6e-19
Identities = 57/189 (30%), Positives = 117/189 (61%), Gaps = 7/189 (3%)
Query: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK-- 92
+ +K R++ EK R+ EK R++E +E++++ R+ K RE++ RE+++ +EK
Sbjct: 501 QEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIW 560
Query: 93 ERRKRKKEKKKRERKQRGRRERKKK---KERKERERENK-QRRERKRKKRRKKKRRKERK 148
E KR++++ K R++ RE+++K +E K RE+E K Q +E K K+ +K R +E K
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEK 620
Query: 149 -REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207
+E+E RE++ K R++EE +++E E++++ +E + +++E R+++K R++
Sbjct: 621 IQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQ 680
Query: 208 DRKTDRQTD 216
++K Q +
Sbjct: 681 EKKIREQEE 689
Score = 90.9 bits (224), Expect = 1e-18
Identities = 61/208 (29%), Positives = 122/208 (58%), Gaps = 22/208 (10%)
Query: 31 QRESERKKERREREKRKRER--EKERKRERGK-----KEKKKRK-------KRERGKERE 76
+R+ E E+ E+ +R+ E EKE K R + KE+K R+ K E+ +E E
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 397
Query: 77 RKRKEREK--QRKERREKERRKRKKEKKKRERKQRGRRERK-KKKERKERERENKQRRER 133
K E+EK +++E+R++E + R++EK++ + + R+E K +++E K RE+E K R+
Sbjct: 398 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 457
Query: 134 KRKKRRKKKRRKERKREKERGKRERKRKKRKKE---EREKKRERNRKERKKERE--RKER 188
++ ++K R +E+++E+E R+ ++ ++E ++EK E+ K RK+E + R+E
Sbjct: 458 EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE 517
Query: 189 RERKKERKKERRKKKERKKDRKTDRQTD 216
+ R++E K +++K +++ K Q +
Sbjct: 518 KIREQEEKIREQEEKMWRQEEKIREQEE 545
Score = 90.1 bits (222), Expect = 2e-18
Identities = 52/182 (28%), Positives = 114/182 (62%), Gaps = 6/182 (3%)
Query: 32 RESERKKERRE--REKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
RE E+++E+ E R++ K ++E R++ K +++ K R++ ++ R+ ++ +Q ++
Sbjct: 467 REEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKI 526
Query: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
RE+E + ++E+K RE+++ R E K ++ K E E +Q +E K ++ +K R +E K
Sbjct: 527 REQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKV 586
Query: 150 EKERGK-RERKRKKRKKEEREKKRE---RNRKERKKERERKERRERKKERKKERRKKKER 205
++ K RE++ K++++EE+ K+E R ++E+ +E+E K R + +K R++E +++
Sbjct: 587 WRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQE 646
Query: 206 KK 207
+K
Sbjct: 647 EK 648
Score = 90.1 bits (222), Expect = 2e-18
Identities = 53/210 (25%), Positives = 127/210 (60%), Gaps = 11/210 (5%)
Query: 32 RESERKKER-----REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKERE--- 83
RE E K R RE+E+ RE EK ++E+ +E+K++++ ++ +E K +E+E
Sbjct: 527 REQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKV 586
Query: 84 -KQRKERREKERRKRKKEKK--KRERKQRGRRERKKKKERKERERENKQRRERKRKKRRK 140
+Q ++ RE+E +++++E+K K+E K R + E+ +++E K RE+E K R + + + ++
Sbjct: 587 WRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQE 646
Query: 141 KKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERR 200
+K ++ ++ E+ ++ +++++ + EK RE+ +K R++E + +E+ E +E++++
Sbjct: 647 EKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 706
Query: 201 KKKERKKDRKTDRQTDSQVFRPLRESAFNR 230
+++E+ +++ Q + R E + +
Sbjct: 707 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 736
Score = 89.0 bits (219), Expect = 4e-18
Identities = 55/201 (27%), Positives = 116/201 (57%), Gaps = 16/201 (7%)
Query: 32 RESERKKERREREKRKREREKERKRER-GKKEKKKRKKRERGKERERKRKEREKQRKERR 90
RE E K R+E ++E + R+ E +KE+K R++ E E+E K + +E+ E+
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 390
Query: 91 EK-----------ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR 139
EK E+ + ++EK++ E K R + +R++++ + R+ E + +E K +++
Sbjct: 391 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 450
Query: 140 KKKRRKERK-REKERGKRERKRKKRKKEEREKKRERNRKE---RKKERERKERRERKKER 195
KK R+E K E+E+ + E KR+++++ R++++ ++E +K++ +E + RK+E
Sbjct: 451 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE 510
Query: 196 KKERRKKKERKKDRKTDRQTD 216
K R+++K R+++ K Q +
Sbjct: 511 KVWRQEEKIREQEEKIREQEE 531
Score = 88.6 bits (218), Expect = 5e-18
Identities = 55/197 (27%), Positives = 121/197 (61%), Gaps = 12/197 (6%)
Query: 31 QRESERKKER---REREKRKREREKERKRERG--KKEKKKRKKRERGKERERKRKEREK- 84
Q E RK+E R+ EK + + EK R++E ++E+K R++ E +E E K E+EK
Sbjct: 501 QEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE-KMHEQEKI 559
Query: 85 -QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR----RERKRKKRR 139
+ ++R+E+E + ++E+K RE++++ R+ +K +E++E+ +E +++ E+ R++
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 619
Query: 140 KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER 199
K + ++E+ RE+E RE++ +++EE+ ++E E++++ + +E ++E K
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE 679
Query: 200 RKKKERKKDRKTDRQTD 216
++KK R+++ K Q +
Sbjct: 680 QEKKIREQEEKIREQEE 696
Score = 88.6 bits (218), Expect = 5e-18
Identities = 61/203 (30%), Positives = 128/203 (63%), Gaps = 18/203 (8%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKERE----KQRK 87
RE E +K R + EK R+ EK R++E +E++K ++E+ E E KR+E+E +Q +
Sbjct: 520 REQE-EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE-KRQEQEDKMWRQEE 577
Query: 88 ERREKERRKRKKEKKKRERKQRGRRERKK--KKERKERERENK-QRRERKRKKRRKKKRR 144
+ RE+E + ++E+K RE++++ + + +K K+E K RE+E K Q +E K +++ +K R
Sbjct: 578 KIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIRE 637
Query: 145 KE---RKREKERGKRERK--RKKRKKEERE----KKRERNRKERKKERERKERRERKKER 195
+E +++E++ G++E K ++ K +E+E ++ E+ R++ KK RE++E+ ++E
Sbjct: 638 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEM 697
Query: 196 KKERRKKKERKKDRKTDRQTDSQ 218
+E+ +K ++++ +++ Q
Sbjct: 698 MQEQEEKMWEQEEKMCEQEEKMQ 720
Score = 88.2 bits (217), Expect = 7e-18
Identities = 46/181 (25%), Positives = 119/181 (65%), Gaps = 5/181 (2%)
Query: 35 ERKKERREREKRKREREKERKRERG--KKEKKKRKKRERGKERERKRKEREKQRKERRE- 91
E+++ R++EK + EK RK+E ++E+K R++ E+ +E+E K +E++ +E+ E
Sbjct: 487 EQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEM 546
Query: 92 --KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
+E + ++EK E K++ + ++ ++E K RE+E K R+ ++ + +++KR+++ ++
Sbjct: 547 WREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
Query: 150 EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDR 209
++ ++ R+++++ +E+ EK RE+ K R++E +E+ E+ E++++ +++E+ +++
Sbjct: 607 MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666
Query: 210 K 210
+
Sbjct: 667 E 667
Score = 85.9 bits (211), Expect = 4e-17
Identities = 50/212 (23%), Positives = 117/212 (55%), Gaps = 2/212 (0%)
Query: 8 RAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRK 67
RA + L + H+ K ++ + + E E R +++ ++ ++E+K ++
Sbjct: 253 RAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK-MWRQEEKIQE 311
Query: 68 KRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKEREREN 127
E+ +E+E K +E+E++ +E+ EK RR+ + +K E+ +R +K+E+ R+ E
Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 371
Query: 128 KQRRERKRKKRRKKKRRKERK-REKERGKRERKRKKRKKEEREKKRERNRKERKKERERK 186
+E K +++ + KE K RE E E+++ + ++E+R+++ + +E+++E+E K
Sbjct: 372 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 431
Query: 187 ERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
R+ +K R++E + +++ KK + + + Q
Sbjct: 432 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ 463
Score = 85.9 bits (211), Expect = 4e-17
Identities = 49/189 (25%), Positives = 120/189 (63%), Gaps = 3/189 (1%)
Query: 31 QRESERKKERREREKRKRE-REKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Q E R++E + RE+ ++ R++E+ RE+ + +++ K E+ K E ++++ ++ + R
Sbjct: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWR 574
Query: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR-RERKRKKRRKKKRRKERK 148
+E++ R+++++ ++E K R + E+++++E K ++E K R +E K +++ +K R +E K
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634
Query: 149 -REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207
RE+E +E++ K ++EE+ ++E +E+++ R+E + R++E+K +++K R++
Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ 694
Query: 208 DRKTDRQTD 216
+ Q +
Sbjct: 695 EEMMQEQEE 703
Score = 75.1 bits (183), Expect = 6e-14
Identities = 44/157 (28%), Positives = 99/157 (63%), Gaps = 5/157 (3%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
RE E K++ +E EK ++ EK R++E +E++++ + + K RE++ +E++ K +
Sbjct: 594 REQEEKRQEQE-EKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652
Query: 92 KERRKRKKEKKKRERKQRGRRERK-KKKERKERERENKQRRERKRKKRRKKK--RRKERK 148
+E+ ++EK + + + R+E K +++E+K RE+E K R + + + +++K ++E+
Sbjct: 653 EEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM 712
Query: 149 REKERGKRERKRKKRKKEEREKKRE-RNRKERKKERE 184
E+E +E++ K R++EE+ ++E R R++ +K +E
Sbjct: 713 CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 72.8 bits (177), Expect = 3e-13
Identities = 35/156 (22%), Positives = 98/156 (62%), Gaps = 4/156 (2%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
+ + E+++E+ E+ ++ E+ +E++ + ++E+K R++ E+ +E+E +E+E++ E+
Sbjct: 594 REQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQE 653
Query: 91 EK----ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
EK E + +++E+ ++++ R + KK +E++E+ RE ++ + + +K +++ +
Sbjct: 654 EKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 713
Query: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKKE 182
+ EK + + E+ R++ +K ++ R R ++E+ +E
Sbjct: 714 EQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 68.6 bits (166), Expect = 6e-12
Identities = 49/193 (25%), Positives = 108/193 (55%), Gaps = 13/193 (6%)
Query: 39 ERREREKRKREREKERKRERGK----KEKKKRKKRERGKERERKRKEREKQRKERREKER 94
E + E + +E +RK ER K +++ + + GKE + + + Q +E R
Sbjct: 234 ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR 293
Query: 95 RKRKKEKKKRERKQRGRRERKKKKERKERERENKQR-RERKRKKRRKKK---RRKERKRE 150
+++E+K ++++ + +K +E++E+ RE +++ RE++ K RR+++ ++E+ R
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 151 KERGKRERKRKKRKKEER--EKKRERNRKER---KKERERKERRERKKERKKERRKKKER 205
+E E++ K R++EE EK+ + R+E +KE + +E E+ E++K R ++++R
Sbjct: 354 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 413
Query: 206 KKDRKTDRQTDSQ 218
+++ K Q Q
Sbjct: 414 QEEEKIREQEKRQ 426
Score = 58.2 bits (139), Expect = 8e-09
Identities = 43/199 (21%), Positives = 102/199 (51%), Gaps = 16/199 (8%)
Query: 34 SERKKERREREKRKREREK------------ERKRERGKKEKKKRKKRERGKERERKRKE 81
+++KK R E+ +ER+ E +E+ K ++K + E K + +
Sbjct: 186 TQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVK 245
Query: 82 REKQRKERRE----KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKK 137
K++ ER + +++ + + + +E + + + + +E + R N+Q+ E+ ++
Sbjct: 246 ELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQ 305
Query: 138 RRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKK 197
K + +E+ +E+E RE++ K R++EE+ +++E E++++ R+E +KE K
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 198 ERRKKKERKKDRKTDRQTD 216
R+++ +K+ K RQ +
Sbjct: 366 RRQEEMMWEKEEKMRRQEE 384
Score = 58.2 bits (139), Expect = 8e-09
Identities = 28/107 (26%), Positives = 69/107 (64%), Gaps = 4/107 (3%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
TQ + E+ E+ E+ + E+ +E++ ++E+K R++ ++ +E+E K +E+E+ +E+
Sbjct: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQ 701
Query: 90 REK----ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE 132
EK E + ++E+K +E++++ RR+ +K E++ R R+ +++ +
Sbjct: 702 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Score = 53.5 bits (127), Expect = 2e-07
Identities = 47/228 (20%), Positives = 104/228 (45%), Gaps = 9/228 (3%)
Query: 3 KAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKE 62
K + R +L E +S T E + K + + + + E EK + K+
Sbjct: 188 KKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKEL 247
Query: 63 KKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE 122
K+K ++ + +++ + E + KE + K + + E + R ++++E+
Sbjct: 248 KRKLERAKLLLPQQQLQAEADHLGKELQSVSA----KLQAQVEENELWNRLNQQQEEKMW 303
Query: 123 RERENKQRRERKRKKRRKKKRRKERK--REKERGKRERKRKKRKKEEREKKRERNRKERK 180
R+ E Q E K +++ +K R +E K ++E+ +R+ + K+E+ ++ E ++ +
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363
Query: 181 KERERKE---RRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
K R ++E +E K R++E +KE K ++ + + R E
Sbjct: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 411
Score = 49.7 bits (117), Expect = 3e-06
Identities = 29/97 (29%), Positives = 61/97 (62%), Gaps = 6/97 (6%)
Query: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKERE--- 83
K C Q E +E+ E R+ E+ +E++++ ++E+K R++ E +E+E K E+E
Sbjct: 655 KMCEQEEK--MQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM 712
Query: 84 -KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKE 119
+Q ++ +E+E + R++E+K E++ R R++ +K +E
Sbjct: 713 CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 45.1 bits (105), Expect = 7e-05
Identities = 46/223 (20%), Positives = 93/223 (41%), Gaps = 19/223 (8%)
Query: 15 TELQMVS--CSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERG 72
TELQM H K + + K E E+ +K+K R E
Sbjct: 140 TELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELT 199
Query: 73 KERERKRKE------REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERK----- 121
KER+ E +++ KE+ K + K + + ++ Q +E K+K ER
Sbjct: 200 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP 259
Query: 122 ------ERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERN 175
E + K+ + K + + + + R ++ + + R++ K +E E+K +
Sbjct: 260 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 319
Query: 176 RKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
++ +++ E+ +E K R++E +KE K R+ + + +
Sbjct: 320 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 362
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 102 bits (253), Expect = 5e-22
Identities = 59/204 (28%), Positives = 126/204 (61%), Gaps = 18/204 (8%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
RE E KK R++ EK R+ E+ R++E +E++++ R+ + RE++++ RE++++ R +
Sbjct: 282 REQE-KKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQ 340
Query: 92 KERRKRKKEKKKRERKQRGRRERKKKKERK---ERER---ENKQRRERKRKKRRKKKR-- 143
KE R+++++ +++E K + E+ +++E K + ER + KQ RE+++K R +++R
Sbjct: 341 KELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 400
Query: 144 -RKERKREKERGKRER--------KRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
+ ER REKE RE+ K ++ KK + ++K+ R+++E+ +E ER RE+K
Sbjct: 401 EQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMR 460
Query: 195 RKKERRKKKERKKDRKTDRQTDSQ 218
++E +++E K ++ + + +
Sbjct: 461 EEEETMREQEEKMQKQEENMWEQE 484
Score = 102 bits (253), Expect = 5e-22
Identities = 60/192 (31%), Positives = 123/192 (64%), Gaps = 16/192 (8%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRK---------E 81
+R E++KE RE+EK RE+++ R++E +E++++ + K RE++ K E
Sbjct: 321 KRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWE 380
Query: 82 REKQRKER----REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENK--QRRERKR 135
+EKQ +E+ R++E R +++++ RE+++R RE++K E+ E+ RE K Q +E+K
Sbjct: 381 QEKQMREQEQKMRDQEERMWEQDERLREKEER-MREQEKMWEQVEKMREEKKMQEQEKKT 439
Query: 136 KKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKER 195
+ + +K + +ER RE+E+ RE + R++EE+ +K+E N E++++ +++R +KE+
Sbjct: 440 RDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 499
Query: 196 KKERRKKKERKK 207
E+ K +E+++
Sbjct: 500 LWEQEKMQEQEE 511
Score = 101 bits (252), Expect = 6e-22
Identities = 57/201 (28%), Positives = 124/201 (61%), Gaps = 22/201 (10%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
RE E K R+E+ R++E+E + + +++K+ R++ E+ +E+E K E+E++ +E+ E
Sbjct: 310 REQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEE 369
Query: 92 K-----------ERRKRKKEKKKRERKQRGRRERKKKKERKERERE--------NKQRRE 132
K E++ R++E+K R++++R + ++ +E++ER RE K R E
Sbjct: 370 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREE 429
Query: 133 RKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRE---RNRKERKKERERKERR 189
+K +++ KK R +E K ++E RER++K R++EE +++E + ++E E+E KE +
Sbjct: 430 KKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ 489
Query: 190 ERKKERKKERRKKKERKKDRK 210
+++ +KE+ ++E+ ++++
Sbjct: 490 QQRLPEQKEKLWEQEKMQEQE 510
Score = 99.4 bits (246), Expect = 3e-21
Identities = 54/195 (27%), Positives = 126/195 (64%), Gaps = 5/195 (2%)
Query: 36 RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERR 95
+++E RE+EK+ R++E++ R+ + +++ K RE+ ++ R+ K +Q KE RE+E+
Sbjct: 277 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKE 336
Query: 96 KRK-KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERG 154
R+ KE +++E + + + E+ ++E K RE+E K R+ +R ++K+ R++ ++ +++
Sbjct: 337 LREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 396
Query: 155 KR--ERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERK--KERRKKKERKKDRK 210
+R E+ + R+KEER +++E+ ++ +K RE K+ +E++K+ + +E+ +++ER ++R+
Sbjct: 397 ERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRERE 456
Query: 211 TDRQTDSQVFRPLRE 225
+ + + R E
Sbjct: 457 KKMREEEETMREQEE 471
Score = 97.1 bits (240), Expect = 2e-20
Identities = 60/220 (27%), Positives = 134/220 (60%), Gaps = 15/220 (6%)
Query: 4 AISSRAAVKLNTE--LQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKK 61
A S ++ ++LN + + + + P Q + +++ R+ E+ + + +K RK+E
Sbjct: 237 AESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMW 296
Query: 62 EKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERK 121
+++R + + GK RE++ K +Q K RE+E+ R++EK+ RE+K+ R+++++ +
Sbjct: 297 RQEERLREQEGKMREQEEK-MWRQEKRLREQEKELREQEKELREQKEL----REQEEQMQ 351
Query: 122 ERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEER---EKKRERNRKE 178
E+E + ++ E+ R++ K R++ER E+E+ RE+++K R +EER + +R R ++E
Sbjct: 352 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 411
Query: 179 RKKERER-----KERRERKKERKKERRKKKERKKDRKTDR 213
R +E+E+ ++ RE KK +++E++ + + +K ++ +R
Sbjct: 412 RMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEER 451
Score = 97.1 bits (240), Expect = 2e-20
Identities = 58/192 (30%), Positives = 119/192 (61%), Gaps = 12/192 (6%)
Query: 31 QRESERKKERR--EREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKE 88
Q + R +E R E+++R RE+E ER RE+ K ++ K RE K +E+++K R+++ K
Sbjct: 388 QEQKMRDQEERMWEQDERLREKE-ERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKM 446
Query: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
+ E+ R+R+K+ ++ E R + E+ +K+E E+E K+ ++++ ++++K +E+
Sbjct: 447 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 506
Query: 149 REKERGKRERKRKKRKKEE---REKKRERNRKERKKERERKERRERKKER------KKER 199
+E+E E++ K R +EE +EKK R K R++E + E+ E+ +++ ++ER
Sbjct: 507 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 566
Query: 200 RKKKERKKDRKT 211
+KK +++++KT
Sbjct: 567 MEKKTQEQEKKT 578
Score = 96.7 bits (239), Expect = 2e-20
Identities = 55/205 (26%), Positives = 119/205 (58%), Gaps = 8/205 (3%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
+ + +++E++ R++ ++ +E+ER RER EKK R++ E +E+E K +++E+ E+
Sbjct: 428 EEKKMQEQEKKTRDQEEKMQEEERIRER---EKKMREEEETMREQEEKMQKQEENMWEQE 484
Query: 91 EKE----RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
EKE R +KEK + K + + E+ ++E K R++E +E+K ++ K + +++
Sbjct: 485 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 544
Query: 147 RKREKERGKRERKRKKRKKEER-EKKRERNRKERKKERERKERRERKKERKKERRKKKER 205
+ E+E R++++K +EER EKK + K+ + E+ ER +ER+K+ R+++E
Sbjct: 545 QMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 604
Query: 206 KKDRKTDRQTDSQVFRPLRESAFNR 230
++++ Q + + E + +
Sbjct: 605 MREQEEKMQEQEEKMQEQEEKMWEQ 629
Score = 94.7 bits (234), Expect = 8e-20
Identities = 62/212 (29%), Positives = 120/212 (56%), Gaps = 24/212 (11%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKR---------ERGKERERKRKE 81
Q E R+KE R RE+ K + E+ RE K +++++K R ER +ERE+K +E
Sbjct: 402 QDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMRE 461
Query: 82 REKQRKERREKERRKRKK--EKKKRERKQRGRRERKKK---------KERKERERENKQR 130
E+ +E+ EK +++ + E++++E +Q+ E+K+K +E K E+E K R
Sbjct: 462 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 521
Query: 131 RERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEER----EKKRERNRKERKKERERK 186
+ + + KK R+E+ RE+E E++ K R +E++ E++ E+ +E++K+ +
Sbjct: 522 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQ 581
Query: 187 ERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
E + R++ER +ER KK +++ +++ Q
Sbjct: 582 EEKMREEERMREREKKMREEEEMMREQEEKMQ 613
Score = 93.2 bits (230), Expect = 2e-19
Identities = 48/189 (25%), Positives = 120/189 (63%), Gaps = 3/189 (1%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
T RE E K +++E ++E EKE +++R ++K+K ++E+ +E+E K E+E++ +++
Sbjct: 465 TMREQEEKMQKQEENMWEQE-EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 523
Query: 90 REK--ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKER 147
E + +K +++K RE++ + + +K ++++++ + ++R E+K +++ KK +E
Sbjct: 524 EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEE 583
Query: 148 KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207
K +E RER++K R++EE +++E +E++++ + +E + ++E K + +++K ++
Sbjct: 584 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643
Query: 208 DRKTDRQTD 216
+ K Q +
Sbjct: 644 EEKMWEQEE 652
Score = 91.3 bits (225), Expect = 8e-19
Identities = 47/177 (26%), Positives = 115/177 (64%), Gaps = 4/177 (2%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
+E E+K +E + R+ ER +ER+++ ++E+ R++ E+ +E+E K +E+E++ E+ E
Sbjct: 572 QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEE 631
Query: 92 KERRKRKK---EKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
K + + +K +++K ++ E+++ E+KE+ E+++ +E+++ + +++K ++ K
Sbjct: 632 KMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEK 691
Query: 149 REKERGKRERKR-KKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE 204
EK+ ++E+K + K E E RER +K R++E +E+ E+ +E++++ ++++E
Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 748
Score = 90.9 bits (224), Expect = 1e-18
Identities = 57/193 (29%), Positives = 122/193 (63%), Gaps = 16/193 (8%)
Query: 32 RESERKKERREREKR-----KREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
+E +K+ +E+EK+ ++ RE+ER RER EKK R++ E +E+E K +E+E++
Sbjct: 563 QEERMEKKTQEQEKKTWDQEEKMREEERMRER---EKKMREEEEMMREQEEKMQEQEEKM 619
Query: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKK-RRKKKRRK 145
+E+ EK ++E+K +E++++ + +K E++E+ E ++ E+K K +K + +
Sbjct: 620 QEQEEK---MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ 676
Query: 146 ERKREKERGKRERKRKKRKKEEREKK---RERNRKERK-KERERKERRERKKERKKERRK 201
E+ +E+E E+++ ++K +E+EKK +E+ R+E +ERE+K R E + R++E +
Sbjct: 677 EKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKM 736
Query: 202 KKERKKDRKTDRQ 214
+++ +K ++ + +
Sbjct: 737 QEQEEKMQEQEEE 749
Score = 90.9 bits (224), Expect = 1e-18
Identities = 53/196 (27%), Positives = 114/196 (58%), Gaps = 8/196 (4%)
Query: 27 KPCTQRESERKKER-REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
K Q E R++ER REREK+ RE E+E RE+ E+K +++ E+ +E+E K E+E++
Sbjct: 577 KTWDQEEKMREEERMREREKKMRE-EEEMMREQ---EEKMQEQEEKMQEQEEKMWEQEEK 632
Query: 86 RKERREK---ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK 142
+E+ EK + K ++++K +QR +++K E ++ + + K + + ++ ++K
Sbjct: 633 MQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKM 692
Query: 143 RRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKK 202
+K +++EK+ +E+ R++ EREKK + +++ E+ + +E K + ++E +
Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWE 752
Query: 203 KERKKDRKTDRQTDSQ 218
+E K + ++ + Q
Sbjct: 753 QEEKMWEQEEKMWEQQ 768
Score = 90.5 bits (223), Expect = 1e-18
Identities = 47/189 (24%), Positives = 121/189 (64%), Gaps = 3/189 (1%)
Query: 32 RESERKKERRE--REKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
+E ER +ER + RE+ + RE+E K ++ ++ +++++E ++R ++KE+ ++++
Sbjct: 447 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 506
Query: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
+E+E + ++E+K R++++ +E+K ++ K RE+E+ Q E++ K R ++++ +++
Sbjct: 507 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED-QMWEQEEKMRDQEQKMWDQEE 565
Query: 150 EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDR 209
E+ +E+++K +EE+ ++ ER R+ KK RE +E ++E+ +E+ +K + ++++
Sbjct: 566 RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEK 625
Query: 210 KTDRQTDSQ 218
+++ Q
Sbjct: 626 MWEQEEKMQ 634
Score = 90.1 bits (222), Expect = 2e-18
Identities = 51/184 (27%), Positives = 114/184 (61%), Gaps = 8/184 (4%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE- 91
+ E+ +E+ E+ R+ ER E++++ ++E+K R + ER E++ + +E+E++ +E+ +
Sbjct: 360 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 419
Query: 92 -KERRKRKKEKKKRERKQRGR-RERKKKKERKERERENKQRRERKRKKRRKKKRRKE--- 146
++ K ++EKK +E++++ R +E K ++E + RERE K R E + + +++K +K+
Sbjct: 420 WEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 479
Query: 147 --RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE 204
+ EKE ++ +K K E+EK +E+ K ++E + +++ E + KK R++K
Sbjct: 480 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 539
Query: 205 RKKD 208
R+++
Sbjct: 540 REQE 543
Score = 90.1 bits (222), Expect = 2e-18
Identities = 50/195 (25%), Positives = 123/195 (63%), Gaps = 7/195 (3%)
Query: 31 QRESERKKER-REREKRKRE-----REKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
Q E +++ER REREK+ RE RE+E K ++ ++ +++++E ++R ++KE+
Sbjct: 442 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 501
Query: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ-RRERKRKKRRKKKR 143
++++ +E+E + ++E+K R++++ +E+K ++ K RE+E++ +E K + + +K
Sbjct: 502 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 561
Query: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
+E + EK+ ++E+K ++++ RE++R R R+++ +E E R + +K +++E + ++
Sbjct: 562 DQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621
Query: 204 ERKKDRKTDRQTDSQ 218
+ +K + + + Q
Sbjct: 622 QEEKMWEQEEKMQEQ 636
Score = 87.8 bits (216), Expect = 9e-18
Identities = 46/206 (22%), Positives = 127/206 (61%), Gaps = 10/206 (4%)
Query: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER---RE 91
E++++ R++E++ ++E+ +++ ++EKK + E+ +E ER R+ +K R+E RE
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 607
Query: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR---RERKRKKRRKKKRRKERK 148
+E + +++E+K +E++++ + +K +E++E+ E +++ +E K ++++ +KE+
Sbjct: 608 QEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667
Query: 149 REKERGKRERKRKKRKKE--EREKKRERNRKERKK--ERERKERRERKKERKKERRKKKE 204
E E+ + + K ++++++ E+EK ++ +++ KK ++E+ E +ER+K+ R+++E
Sbjct: 668 WEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Query: 205 RKKDRKTDRQTDSQVFRPLRESAFNR 230
++++ Q + + E + +
Sbjct: 728 MMREQEEKMQEQEEKMQEQEEEMWEQ 753
Score = 87.0 bits (214), Expect = 2e-17
Identities = 51/204 (25%), Positives = 118/204 (57%), Gaps = 5/204 (2%)
Query: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
K ++E R++E + E+ ++ R++E+K ++ +K+ + + K +++ K RE++R
Sbjct: 531 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER 590
Query: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENK-QRRERKRKKRRKKKRRK 145
REK+ R+ ++ +++E K + + E+ +++E K E+E K Q +E K ++ +K +
Sbjct: 591 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650
Query: 146 ERKREKERGKRERKRK---KRKKEEREKKRERNRKERKKER-ERKERRERKKERKKERRK 201
E K +++ E+K K K +E+EK +E+ K ++E+ E+K + + KK +E+ +
Sbjct: 651 EEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR 710
Query: 202 KKERKKDRKTDRQTDSQVFRPLRE 225
++E ++R+ + + ++ R E
Sbjct: 711 EEESMREREKKMREEEEMMREQEE 734
Score = 86.7 bits (213), Expect = 2e-17
Identities = 48/202 (23%), Positives = 116/202 (57%), Gaps = 7/202 (3%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Q E ++++ R+++ RE+E + + K +++K ++ + E+K +E+EK+ ++
Sbjct: 523 QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQE 582
Query: 91 EK---ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR----RERKRKKRRKKKR 143
EK E R R++EKK RE ++ R + +K +E++E+ +E +++ E+ +++ K
Sbjct: 583 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWE 642
Query: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
++E+ E+E E++R +KE+ + + +E+ +E+E K + K E+K + ++KK
Sbjct: 643 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Query: 204 ERKKDRKTDRQTDSQVFRPLRE 225
+++ + ++ + + +RE
Sbjct: 703 TWDQEKMREEESMREREKKMRE 724
Score = 86.3 bits (212), Expect = 3e-17
Identities = 54/195 (27%), Positives = 114/195 (58%), Gaps = 11/195 (5%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
QR E+K++ E+EK + + EK ++E +++++ +E+ R+ K +E+E Q E+
Sbjct: 491 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 550
Query: 91 EKERRKRKK--------EKKKRER-KQRGRRERKKKKERKERERENKQRRERK--RKKRR 139
EK R + +K EKK +E+ K+ +E K ++E + RERE K R E + R++
Sbjct: 551 EKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEE 610
Query: 140 KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER 199
K + ++E+ +E+E E++ K +++EE+ ++E E++++ ++R +KE+ E
Sbjct: 611 KMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH 670
Query: 200 RKKKERKKDRKTDRQ 214
K +E++K ++ + +
Sbjct: 671 EKMQEQEKMQEQEEK 685
Score = 86.3 bits (212), Expect = 3e-17
Identities = 52/198 (26%), Positives = 116/198 (58%), Gaps = 18/198 (9%)
Query: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK-- 92
E++K + + EK + EK R +E ++KK ++E+ +E+E + E+E++ +++ +K
Sbjct: 502 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 561
Query: 93 ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK--RKKRRKKKRRKERKRE 150
++ +R ++K + + K+ +E K ++E + RERE K R E + R++ K + ++E+ +E
Sbjct: 562 DQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621
Query: 151 KERGKRERKRKKRKKEER------------EKKRERNRKERKKER--ERKERRERKKERK 196
+E E++ K +++EE+ EK E+ R +KE+ E ++ +E++K ++
Sbjct: 622 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQE 681
Query: 197 KERRKKKERKKDRKTDRQ 214
+E + ++ K ++KT Q
Sbjct: 682 QEEKIWEQEKMEKKTQEQ 699
Score = 84.0 bits (206), Expect = 1e-16
Identities = 45/192 (23%), Positives = 120/192 (62%), Gaps = 6/192 (3%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKE-RRE 91
E E K +E++ +E E+K + +K+ ++++ R +ER R+R+++ ++ +E RE
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 607
Query: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKER--ERENKQ-RRERKRKKRRKKKRRKERK 148
+E + +++E+K +E++++ + +K +E++E+ E+E K +E K ++++ +KE+
Sbjct: 608 QEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667
Query: 149 REKERGKRERKRKKRKKE--EREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
E E+ + + K ++++++ E+EK ++ +++ KK ++++ RE + R++E++ ++E +
Sbjct: 668 WEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Query: 207 KDRKTDRQTDSQ 218
R+ + + Q
Sbjct: 728 MMREQEEKMQEQ 739
Score = 84.0 bits (206), Expect = 1e-16
Identities = 51/189 (26%), Positives = 121/189 (64%), Gaps = 14/189 (7%)
Query: 31 QRESERKKERRE-----REKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
+R ER+K+ RE RE+ ++ +E+E K + ++E+K ++ E+ +E+E K E+E++
Sbjct: 589 ERMREREKKMREEEEMMREQEEKMQEQEEKMQ--EQEEKMWEQEEKMQEQEEKMWEQEEK 646
Query: 86 RKERREK---ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR---R 139
E+ EK ++R ++++K E ++ +E+ +++E K E+E +++ ++++K+ +
Sbjct: 647 MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ 706
Query: 140 KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKER-ERKERRERKKERKKE 198
+K R +E RE+E+ RE + R++EE+ +++E +E+++E E++E+ ++E+ E
Sbjct: 707 EKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWE 766
Query: 199 RRKKKERKK 207
+++ E+K+
Sbjct: 767 QQRLPEQKE 775
Score = 82.8 bits (203), Expect = 3e-16
Identities = 45/180 (25%), Positives = 110/180 (61%), Gaps = 7/180 (3%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Q + E+ +E+ E+ + E+ +E++ + ++E+K ++ E+ E++R +++EK + +
Sbjct: 613 QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 672
Query: 91 EKERRKRKKEKKK---RERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKER 147
+E+ K +++++K +E+ ++ +E++KK +E+ RE + RER++K R + +E
Sbjct: 673 MQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREE----EEM 728
Query: 148 KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207
RE+E +E++ K +++EE ++E E++++ ++R +KE+ E K +E++K
Sbjct: 729 MREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 788
Score = 82.8 bits (203), Expect = 3e-16
Identities = 49/208 (23%), Positives = 119/208 (57%), Gaps = 9/208 (4%)
Query: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
+E E K +E + +++E + + E+ ++++K +++R E++ K E EK +++ +
Sbjct: 620 QEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKM 679
Query: 92 KERRKR-----KKEKKKRERKQRGRRERKKKKERKERERENKQRRERK--RKKRRKKKRR 144
+E+ ++ K EKK +E++++ + K ++E RERE K R E + R++ K + +
Sbjct: 680 QEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQ 739
Query: 145 KERKREKERGKRERKRKKRKKEER--EKKRERNRKERKKERERKERRERKKERKKERRKK 202
+E+ +E+E E++ K ++EE+ E++R +KE+ E E+ + +E+ E++++ R +
Sbjct: 740 EEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQ 799
Query: 203 KERKKDRKTDRQTDSQVFRPLRESAFNR 230
+E+ + ++ + + R E + +
Sbjct: 800 EEKMRGQEEKMRGQEEKMRGQEEKMWGQ 827
Score = 80.9 bits (198), Expect = 1e-15
Identities = 41/181 (22%), Positives = 110/181 (60%), Gaps = 5/181 (2%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
+ ES R++E++ RE+ + RE+E K + ++EK + ++ E ++ E+ ++ EK +++R
Sbjct: 711 EEESMREREKKMREEEEMMREQEEKMQE-QEEKMQEQEEEMWEQEEKMWEQEEKMWEQQR 769
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
E++++ E +K + +++ + +K ++++E+ R +++ + +K R ++ + + E
Sbjct: 770 LPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEE 829
Query: 151 KERGKRER----KRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
K G+ E+ + K +EE+ +++ + ++E+ +E+E K R + +K R++E + + + +
Sbjct: 830 KMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEE 889
Query: 207 K 207
K
Sbjct: 890 K 890
Score = 79.7 bits (195), Expect = 3e-15
Identities = 55/187 (29%), Positives = 108/187 (57%), Gaps = 13/187 (6%)
Query: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGK------ERERKRKERE 83
T E KK+ E +++ E E K E K+ ++K ER K + ++E
Sbjct: 217 TITNEELKKKNAELQEKLPLAESE-KSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMW 275
Query: 84 KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKR 143
+Q +E RE+E KK +K+ E+ R + ER +++E K RE+E K R+ KR + ++K+
Sbjct: 276 RQEEELREQE----KKIRKQEEKMWR-QEERLREQEGKMREQEEKMWRQEKRLREQEKEL 330
Query: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
R++ K +E+ K R+++++ +E+ EK E+ K R++E + + ER E++K+ R+++
Sbjct: 331 REQEKELREQ-KELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 389
Query: 204 ERKKDRK 210
++ +D++
Sbjct: 390 QKMRDQE 396
Score = 79.0 bits (193), Expect = 4e-15
Identities = 46/179 (25%), Positives = 111/179 (62%), Gaps = 8/179 (4%)
Query: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER- 89
QR E+K++ E EK + E+E+ +E+ +K ++ K ++ +E+E+K ++EK R+E
Sbjct: 658 QRLPEQKEKLWEHEKMQ---EQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES 714
Query: 90 -REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
RE+E++ R++E+ RE++++ + + +K +E++E E +++ + +K +++R E
Sbjct: 715 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPE-- 772
Query: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207
+KE+ K ++++K ++++ R+++E+ + +E K R + +K R +E + + +K
Sbjct: 773 -QKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEK 830
Score = 78.6 bits (192), Expect = 6e-15
Identities = 41/175 (23%), Positives = 105/175 (60%), Gaps = 2/175 (1%)
Query: 42 EREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEK 101
E +K+ E +++ +K + + +E ++ ER + + + ++E ++++E
Sbjct: 222 ELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL 281
Query: 102 KKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK--REKERGKRERK 159
+++E+K R + E+ ++E + RE+E K R + ++ R++K+ R++ K RE+E+ RE+K
Sbjct: 282 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQK 341
Query: 160 RKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQ 214
+ ++E+ +++ E+ ++ +K RE++E+ R++ER E+ K+ ++ + D++
Sbjct: 342 ELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 396
Score = 75.5 bits (184), Expect = 5e-14
Identities = 48/202 (23%), Positives = 107/202 (52%), Gaps = 18/202 (8%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
+ + K + +E + ++E+ +++ +E+ KK + K RE RER++K RE++ R ++
Sbjct: 674 QEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQE 733
Query: 93 ERRKRKKEKKKRERKQRGRRERK------------KKKERKER--ERENKQRRERKRKKR 138
E+ + ++EK + + ++ +E K + E+KE+ E E Q +E+ ++
Sbjct: 734 EKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQE 793
Query: 139 RKKKRRKERKREKERGKRERKRKKRKKEER----EKKRERNRKERKKERERKERRERKKE 194
K + ++E+ R +E R ++ K R +EE+ E+K ++ + E+ +E K E
Sbjct: 794 EKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKME 853
Query: 195 RKKERRKKKERKKDRKTDRQTD 216
K + +++K R+++ K Q +
Sbjct: 854 EKMQGQEEKMREQEEKMRGQEE 875
Score = 66.2 bits (160), Expect = 3e-11
Identities = 51/192 (26%), Positives = 103/192 (53%), Gaps = 14/192 (7%)
Query: 34 SERKKERREREKRKREREK---ERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
+ KK R E+ +ER+ E R E+ K+K E ++ E+ + + +
Sbjct: 190 TRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVK 249
Query: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
E +R+ + + + + +E ++E + RE+E K RK+ K R++ER RE
Sbjct: 250 ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK-----IRKQEEKMWRQEERLRE 304
Query: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKE-RERKERRERKKERKKERRK-----KKE 204
+E RE++ K ++E+R +++E+ +E++KE RE+KE RE++++ +++ K +K
Sbjct: 305 QEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKM 364
Query: 205 RKKDRKTDRQTD 216
R+++ K RQ +
Sbjct: 365 REQEEKMWRQEE 376
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 102 bits (253), Expect = 5e-22
Identities = 61/182 (33%), Positives = 114/182 (62%), Gaps = 10/182 (5%)
Query: 43 REKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRK---K 99
++ ++E+ RK E+ +KEKK + +E+ +E ER+++ RE+Q K RRE ER+KR+ +
Sbjct: 89 QQMSRKEKVHHRKDEK-RKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAR 147
Query: 100 EKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERK 159
E +RER + + ERK+++ERK RE++ K++RE+K ++RR ++RRKER+ +E R
Sbjct: 148 EHSRRERDRLEQLERKRERERKMREQQ-KEQREQKERERRAEERRKEREARREVSAHHRT 206
Query: 160 RKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRK----TDRQT 215
++ ++ K +R + RER E + +K K+E+ ++++ D + ++R+T
Sbjct: 207 MRE-DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKT 265
Query: 216 DS 217
S
Sbjct: 266 SS 267
Score = 99.4 bits (246), Expect = 3e-21
Identities = 72/247 (29%), Positives = 133/247 (53%), Gaps = 16/247 (6%)
Query: 41 REREKRKREREK-ERKRERGKKEK-KKRKKRERGKERERKRKEREKQRKERREKERRKRK 98
+E+++RK + EK E KR + ++ KR E G+ R+ + + RRE R
Sbjct: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
Query: 99 KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRER 158
+E K + RK+K ++ E+ +++ R ++K R+ +RRK + E+++ +RE
Sbjct: 78 EEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREW 137
Query: 159 KRKKRKKEERE-KKRERNR---KERKKERERKERRERK--KERKKERRKKKERKKDRKTD 212
+R+KR++ RE +RER+R ERK+ERERK R ++K +E+K+ R+ +ER+K+R+
Sbjct: 138 ERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREAR 197
Query: 213 RQTDSQVFRPLRESAFNRVTVTGVFR------YRIFHTGLDHFPIKTNILLSRHEVNDGE 266
R+ + R +RE ++V + R F G P+K + R ++D +
Sbjct: 198 REVSAH-HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ 256
Query: 267 IEVNDGE 273
+++D E
Sbjct: 257 -DISDSE 262
Score = 95.5 bits (236), Expect = 4e-20
Identities = 60/227 (26%), Positives = 119/227 (52%), Gaps = 32/227 (14%)
Query: 32 RESERKKERREREKRKREREKERKR------ERGKKEKKKRKKRERGKERERKRKEREKQ 85
R+ E++KE++ +++ERE ER++ ++ ++E +++K+RE +E R+ ++R +Q
Sbjct: 100 RKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQ 159
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
+ +RE+ER+ R+++K++RE+K+R RR +++KER+ R RE R+ K +
Sbjct: 160 LERKRERERKMREQQKEQREQKERERRAEERRKEREAR-REVSAHHRTMREDYSDKVKAS 218
Query: 146 ERKREKERGKRER-----KRKKRKKEEREKK------RERNRKERK-------------- 180
R R RER RK K+E+ E++ ++ + ERK
Sbjct: 219 HWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG 278
Query: 181 KERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESA 227
E E +E E ++E ++E +++ + + +T S +SA
Sbjct: 279 SEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 325
Score = 91.3 bits (225), Expect = 8e-19
Identities = 50/202 (24%), Positives = 104/202 (51%), Gaps = 16/202 (7%)
Query: 31 QRESERKKERRE-REKRKREREKERKRERGKKEKKKRKKR----ERGKERERKRKEREKQ 85
+RE ER+K RE ++K +RE E++++RE ++ ++ + R ER +ERERK +E++K+
Sbjct: 117 EREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKE 176
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
++E++E+ERR ++ K++ R++ R +++ ++ + + R R R + +
Sbjct: 177 QREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGD 236
Query: 146 ERKREKERGKRER-----------KRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
RK KE ER +K E + E ++E E +E E
Sbjct: 237 GRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 296
Query: 195 RKKERRKKKERKKDRKTDRQTD 216
+ E +++E +++ +T ++
Sbjct: 297 EESEEEEEEEEEEEEETGSNSE 318
Score = 90.1 bits (222), Expect = 2e-18
Identities = 56/202 (27%), Positives = 109/202 (53%), Gaps = 29/202 (14%)
Query: 32 RESERKKERREREKRKRER---EKERKRE----------------RGKKEKKKRKKRERG 72
+E +R+KE+ E+ + KR + +++ KR+ R +++ +RG
Sbjct: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
Query: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE 132
+E + + +Q + + RK +K K+K+ + + +ER+ ++ ++ RE ++K RRE
Sbjct: 78 EEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVK-EKEREHERRKRHREEQDKARRE 136
Query: 133 RKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERK 192
+R+KRR E RE R +R+R + +K ERE+K +KE+++++ER+ R E
Sbjct: 137 WERQKRR------EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAE-- 188
Query: 193 KERKKERRKKKERKKDRKTDRQ 214
ER+KER ++E +T R+
Sbjct: 189 -ERRKEREARREVSAHHRTMRE 209
Score = 80.1 bits (196), Expect = 2e-15
Identities = 59/212 (27%), Positives = 104/212 (49%), Gaps = 27/212 (12%)
Query: 31 QRESERKKER---REREKRKRER----EKERKRERGKKEKKKRKKRERGKERERKRKERE 83
+RE ER+K R RE +R+R+R E++R+RER +E++K ++ + KERER+ +ER
Sbjct: 134 RREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQ--KERERRAEERR 191
Query: 84 KQRKERRE-----KERRKRKKEKKK------------RERKQRGRRERKKKKERKERERE 126
K+R+ RRE + R+ +K K RER + G RK KE K ER+
Sbjct: 192 KEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG-DGRKPVKEEKMEERD 250
Query: 127 NKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERK 186
+ RK + E G E + ++ ++EE E + +E ++E E +
Sbjct: 251 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEE 310
Query: 187 ERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
E E E+ ++ +++ D + +++
Sbjct: 311 EETGSNSEEASEQSAEEVSEEEMSEDEERENE 342
Score = 42.4 bits (98), Expect = 4e-04
Identities = 41/205 (20%), Positives = 86/205 (41%), Gaps = 51/205 (24%)
Query: 31 QRESERKKERREREKRKRE-REKERKRERGKKEKKKRKK--------------------- 68
+R+ ER+++ RE++K +RE +E+ER+ E +KE++ R++
Sbjct: 161 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 220
Query: 69 --------RER-----GKE--RERKRKERE----------KQRK----ERREKERRKRKK 99
RER G++ +E K +ER+ +RK E E +
Sbjct: 221 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 280
Query: 100 EKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERK 159
E+++ E ++ ++ E +E E E ++ + ++ +E E+ ER+
Sbjct: 281 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 340
Query: 160 RKKRKKEEREKKRERNRKERKKERE 184
+ E + +R+ E ++ E
Sbjct: 341 NENHLLVVPESRFDRDSGESEEAEE 365
Score = 35.0 bits (79), Expect = 0.071
Identities = 24/128 (18%), Positives = 55/128 (42%), Gaps = 5/128 (3%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
+ E+ +ER + + ERK + + +E E + +E E E E+
Sbjct: 242 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 301
Query: 93 ERRKRKKEKKK-----RERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKER 147
E + ++E+++ E ++ E +++ ++ EREN+ + R + +
Sbjct: 302 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 361
Query: 148 KREKERGK 155
+ E+E G+
Sbjct: 362 EAEEEVGE 369
Score = 32.7 bits (73), Expect = 0.35
Identities = 24/119 (20%), Positives = 49/119 (41%), Gaps = 5/119 (4%)
Query: 13 LNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERG 72
L ++LQ +S S + S E E+ + E E+E + E+++ ++ E
Sbjct: 251 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEE 310
Query: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRER-----KQRGRRERKKKKERKERERE 126
+E +E +Q E +E +E++ + R R+ + +E +E E
Sbjct: 311 EETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 369
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 102 bits (253), Expect = 5e-22
Identities = 61/182 (33%), Positives = 114/182 (62%), Gaps = 10/182 (5%)
Query: 43 REKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRK---K 99
++ ++E+ RK E+ +KEKK + +E+ +E ER+++ RE+Q K RRE ER+KR+ +
Sbjct: 55 QQMSRKEKVHHRKDEK-RKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAR 113
Query: 100 EKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERK 159
E +RER + + ERK+++ERK RE++ K++RE+K ++RR ++RRKER+ +E R
Sbjct: 114 EHSRRERDRLEQLERKRERERKMREQQ-KEQREQKERERRAEERRKEREARREVSAHHRT 172
Query: 160 RKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRK----TDRQT 215
++ ++ K +R + RER E + +K K+E+ ++++ D + ++R+T
Sbjct: 173 MRE-DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKT 231
Query: 216 DS 217
S
Sbjct: 232 SS 233
Score = 95.5 bits (236), Expect = 4e-20
Identities = 60/227 (26%), Positives = 119/227 (52%), Gaps = 32/227 (14%)
Query: 32 RESERKKERREREKRKREREKERKR------ERGKKEKKKRKKRERGKERERKRKEREKQ 85
R+ E++KE++ +++ERE ER++ ++ ++E +++K+RE +E R+ ++R +Q
Sbjct: 66 RKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQ 125
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
+ +RE+ER+ R+++K++RE+K+R RR +++KER+ R RE R+ K +
Sbjct: 126 LERKRERERKMREQQKEQREQKERERRAEERRKEREAR-REVSAHHRTMREDYSDKVKAS 184
Query: 146 ERKREKERGKRER-----KRKKRKKEEREKK------RERNRKERK-------------- 180
R R RER RK K+E+ E++ ++ + ERK
Sbjct: 185 HWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG 244
Query: 181 KERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESA 227
E E +E E ++E ++E +++ + + +T S +SA
Sbjct: 245 SEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 291
Score = 92.4 bits (228), Expect = 4e-19
Identities = 64/221 (28%), Positives = 118/221 (53%), Gaps = 14/221 (6%)
Query: 65 KRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERE 124
KR E G+ R+ + + + RRE R +E K + RK+K ++ E
Sbjct: 10 KRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDE 69
Query: 125 RENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE-KKRERNRKE---RK 180
+ +++ R ++K R+ +RRK + E+++ +RE +R+KR++ RE +RER+R E RK
Sbjct: 70 KRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERK 129
Query: 181 KERERKERRERK--KERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVFR 238
+ERERK R ++K +E+K+ R+ +ER+K+R+ R+ + R +RE ++V + R
Sbjct: 130 RERERKMREQQKEQREQKERERRAEERRKEREARREVSAH-HRTMREDYSDKVKASHWSR 188
Query: 239 ------YRIFHTGLDHFPIKTNILLSRHEVNDGEIEVNDGE 273
F G P+K + R ++D + +++D E
Sbjct: 189 SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ-DISDSE 228
Score = 91.3 bits (225), Expect = 8e-19
Identities = 50/202 (24%), Positives = 104/202 (51%), Gaps = 16/202 (7%)
Query: 31 QRESERKKERRE-REKRKREREKERKRERGKKEKKKRKKR----ERGKERERKRKEREKQ 85
+RE ER+K RE ++K +RE E++++RE ++ ++ + R ER +ERERK +E++K+
Sbjct: 83 EREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKE 142
Query: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
++E++E+ERR ++ K++ R++ R +++ ++ + + R R R + +
Sbjct: 143 QREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGD 202
Query: 146 ERKREKERGKRER-----------KRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
RK KE ER +K E + E ++E E +E E
Sbjct: 203 GRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 262
Query: 195 RKKERRKKKERKKDRKTDRQTD 216
+ E +++E +++ +T ++
Sbjct: 263 EESEEEEEEEEEEEEETGSNSE 284
Score = 88.2 bits (217), Expect = 7e-18
Identities = 58/202 (28%), Positives = 104/202 (51%), Gaps = 16/202 (7%)
Query: 26 SKPCTQRESERKKERREREKRKRE-REKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
SK + E E + R E R R ++ +RG+++ K ++ RKE+
Sbjct: 9 SKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIK----PPQQMSRKEKVH 64
Query: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR-RKKKR 143
RK+ + KE++ + ++K+RE ++R R ++ K R+E ER+ ++ R+ +R R +
Sbjct: 65 HRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLE 124
Query: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
+ ERKRE+ER RE+++++R+++ERE++ E RKER E ++E R +
Sbjct: 125 QLERKRERERKMREQQKEQREQKERERRAEERRKER----------EARREVSAHHRTMR 174
Query: 204 ERKKDRKTDRQTDSQVFRPLRE 225
E D+ RP RE
Sbjct: 175 EDYSDKVKASHWSRSPPRPPRE 196
Score = 87.4 bits (215), Expect = 1e-17
Identities = 55/171 (32%), Positives = 95/171 (55%), Gaps = 8/171 (4%)
Query: 40 RREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKK 99
RRE R E + + ++ +++K K+ +RK K+ + +++ RE ERRKR
Sbjct: 34 RREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRH- 92
Query: 100 EKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK-REKERGKRER 158
RE + + RRE +++K R+E RE+ RRER R ++ ++KR +ERK RE+++ +RE+
Sbjct: 93 ----REEQDKARREWERQK-RREMAREHS-RRERDRLEQLERKRERERKMREQQKEQREQ 146
Query: 159 KRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDR 209
K ++R+ EER K+RE R+ R +E K + R ++R
Sbjct: 147 KERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 197
Score = 80.1 bits (196), Expect = 2e-15
Identities = 59/212 (27%), Positives = 104/212 (49%), Gaps = 27/212 (12%)
Query: 31 QRESERKKER---REREKRKRER----EKERKRERGKKEKKKRKKRERGKERERKRKERE 83
+RE ER+K R RE +R+R+R E++R+RER +E++K ++ + KERER+ +ER
Sbjct: 100 RREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQ--KERERRAEERR 157
Query: 84 KQRKERRE-----KERRKRKKEKKK------------RERKQRGRRERKKKKERKERERE 126
K+R+ RRE + R+ +K K RER + G RK KE K ER+
Sbjct: 158 KEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG-DGRKPVKEEKMEERD 216
Query: 127 NKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERK 186
+ RK + E G E + ++ ++EE E + +E ++E E +
Sbjct: 217 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEE 276
Query: 187 ERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
E E E+ ++ +++ D + +++
Sbjct: 277 EETGSNSEEASEQSAEEVSEEEMSEDEERENE 308
Score = 42.4 bits (98), Expect = 4e-04
Identities = 41/205 (20%), Positives = 86/205 (41%), Gaps = 51/205 (24%)
Query: 31 QRESERKKERREREKRKRE-REKERKRERGKKEKKKRKK--------------------- 68
+R+ ER+++ RE++K +RE +E+ER+ E +KE++ R++
Sbjct: 127 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 186
Query: 69 --------RER-----GKE--RERKRKERE----------KQRK----ERREKERRKRKK 99
RER G++ +E K +ER+ +RK E E +
Sbjct: 187 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 246
Query: 100 EKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERK 159
E+++ E ++ ++ E +E E E ++ + ++ +E E+ ER+
Sbjct: 247 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 306
Query: 160 RKKRKKEEREKKRERNRKERKKERE 184
+ E + +R+ E ++ E
Sbjct: 307 NENHLLVVPESRFDRDSGESEEAEE 331
Score = 35.0 bits (79), Expect = 0.071
Identities = 24/128 (18%), Positives = 55/128 (42%), Gaps = 5/128 (3%)
Query: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
+ E+ +ER + + ERK + + +E E + +E E E E+
Sbjct: 208 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 267
Query: 93 ERRKRKKEKKK-----RERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKER 147
E + ++E+++ E ++ E +++ ++ EREN+ + R + +
Sbjct: 268 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 327
Query: 148 KREKERGK 155
+ E+E G+
Sbjct: 328 EAEEEVGE 335
Score = 32.7 bits (73), Expect = 0.35
Identities = 24/119 (20%), Positives = 49/119 (41%), Gaps = 5/119 (4%)
Query: 13 LNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERG 72
L ++LQ +S S + S E E+ + E E+E + E+++ ++ E
Sbjct: 217 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEE 276
Query: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRER-----KQRGRRERKKKKERKERERE 126
+E +E +Q E +E +E++ + R R+ + +E +E E
Sbjct: 277 EETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 335
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.330
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,023,235
Number of Sequences: 37866
Number of extensions: 756221
Number of successful extensions: 162579
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2187
Number of HSP's successfully gapped in prelim test: 549
Number of HSP's that attempted gapping in prelim test: 15197
Number of HSP's gapped (non-prelim): 49298
length of query: 275
length of database: 18,247,518
effective HSP length: 101
effective length of query: 174
effective length of database: 14,423,052
effective search space: 2509611048
effective search space used: 2509611048
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.