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Search of human proteins with 117168269
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117168269 coiled-coil domain containing 33 isoform 2 [Homo
sapiens]
(367 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117168269 coiled-coil domain containing 33 isoform 2 [Homo sa... 724 0.0
gi|117168273 coiled-coil domain containing 33 isoform 1 [Homo sa... 530 e-150
gi|48762942 huntingtin interacting protein-1-related [Homo sapiens] 49 5e-06
gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens] 49 5e-06
gi|31982906 cingulin-like 1 [Homo sapiens] 48 2e-05
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 47 2e-05
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 47 4e-05
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 47 4e-05
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 47 4e-05
gi|153945715 myosin VC [Homo sapiens] 46 5e-05
gi|65301130 kazrin isoform B [Homo sapiens] 46 5e-05
gi|221139761 zinc finger protein 853 [Homo sapiens] 46 6e-05
gi|19923830 pre-B-cell leukemia homeobox interacting protein 1 [... 46 6e-05
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 45 8e-05
gi|45439327 periplakin [Homo sapiens] 45 8e-05
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 45 1e-04
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 45 1e-04
gi|39930479 DIX domain containing 1 isoform b [Homo sapiens] 45 1e-04
gi|83816971 DIX domain containing 1 isoform a [Homo sapiens] 45 1e-04
gi|32698688 citron [Homo sapiens] 45 1e-04
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 44 2e-04
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 44 2e-04
gi|16554562 caspase recruitment domain protein 9 isoform 2 [Homo... 44 2e-04
gi|47717131 caspase recruitment domain protein 9 isoform 1 [Homo... 44 2e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 44 2e-04
gi|21735548 centrosomal protein 2 [Homo sapiens] 44 3e-04
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 43 4e-04
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 43 4e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 43 5e-04
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 43 5e-04
>gi|117168269 coiled-coil domain containing 33 isoform 2 [Homo
sapiens]
Length = 367
Score = 724 bits (1868), Expect = 0.0
Identities = 367/367 (100%), Positives = 367/367 (100%)
Query: 1 MGEPGPPSPPAPKAAPGLIDSFSEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRL 60
MGEPGPPSPPAPKAAPGLIDSFSEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRL
Sbjct: 1 MGEPGPPSPPAPKAAPGLIDSFSEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRL 60
Query: 61 AQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLY 120
AQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLY
Sbjct: 61 AQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLY 120
Query: 121 QAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGK 180
QAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGK
Sbjct: 121 QAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGK 180
Query: 181 PYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPV 240
PYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPV
Sbjct: 181 PYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPV 240
Query: 241 DPGELGAGGDLTERLQETHGPGHSECTETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLE 300
DPGELGAGGDLTERLQETHGPGHSECTETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLE
Sbjct: 241 DPGELGAGGDLTERLQETHGPGHSECTETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLE 300
Query: 301 SQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPVSDPPGVAPRGSGGGAGSHR 360
SQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPVSDPPGVAPRGSGGGAGSHR
Sbjct: 301 SQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPVSDPPGVAPRGSGGGAGSHR 360
Query: 361 TPKVTGP 367
TPKVTGP
Sbjct: 361 TPKVTGP 367
>gi|117168273 coiled-coil domain containing 33 isoform 1 [Homo
sapiens]
Length = 755
Score = 530 bits (1364), Expect = e-150
Identities = 283/318 (88%), Positives = 284/318 (89%), Gaps = 34/318 (10%)
Query: 23 SEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMK 82
+EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMK
Sbjct: 430 TEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMK 489
Query: 83 QKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKA 142
QKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKA
Sbjct: 490 QKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKA 549
Query: 143 LEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENL 202
LEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENL
Sbjct: 550 LEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENL 609
Query: 203 PVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQETHGPG 262
PVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALP
Sbjct: 610 PVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALP----------------------- 646
Query: 263 HSECTETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQ 322
DLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQ
Sbjct: 647 -----------DLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQ 695
Query: 323 EQEKGFRHPSNSIIIEQP 340
EQEKGFRHPSNSIIIEQP
Sbjct: 696 EQEKGFRHPSNSIIIEQP 713
>gi|48762942 huntingtin interacting protein-1-related [Homo sapiens]
Length = 1068
Score = 49.3 bits (116), Expect = 5e-06
Identities = 63/243 (25%), Positives = 104/243 (42%), Gaps = 31/243 (12%)
Query: 24 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQ 83
E+ R+ QK D LR + + L R AQ E E QG EA+ S +
Sbjct: 394 ELEEQRKQKQKALVDNEQLRHELAQL---------RAAQLEGERSQGLREEAERKASATE 444
Query: 84 KLLLSELDMKKLRDRVQHLQNELIRKN-DREKELLLLYQAQQPQAALLKQYQGKLQKMKA 142
+K+ + H+ EL+RKN D K+L + Q+Q+ A + +Q +++++K
Sbjct: 445 ARYNK---LKEKHSELVHVHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQVEQVKR 501
Query: 143 LEETVRHQEK--VIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGE 200
E ++ +EK +EK++R LE + + ++ Q+ +T S L S +
Sbjct: 502 -ESELKLEEKSDQLEKLKRELEAKAGELAR-----AQEALSHT-----EQSKSELSSRLD 550
Query: 201 NLPVE---LYSVLLAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQE 257
L E L + A L R +A + +QQ + GEL G L ER +
Sbjct: 551 TLSAEKDALSGAVRQREADLLAAQSLVRETEAALSREQQRSSQEQGEL--QGRLAERESQ 608
Query: 258 THG 260
G
Sbjct: 609 EQG 611
Score = 33.1 bits (74), Expect = 0.41
Identities = 48/240 (20%), Positives = 95/240 (39%), Gaps = 13/240 (5%)
Query: 94 KLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKV 153
+L+ +V L+ EL + ++++ L+ + + + A L+ Q + ++ + L E +
Sbjct: 383 QLKSQVNALEGELEEQRKQKQKALVDNEQLRHELAQLRAAQLEGERSQGLREEAERKASA 442
Query: 154 IEKMERVLEDRLQDRSKP-PPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLA 212
E L+++ + L R+ + S + + E L ++ V
Sbjct: 443 TEARYNKLKEKHSELVHVHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQVEQVKRE 502
Query: 213 ENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQETHGPGHSECTETLPA 272
KL + D+ + ++ L GEL + +++ S
Sbjct: 503 SELKLEEKSDQ-------LEKLKRELEAKAGELARAQEALSHTEQSKSELSSRLDTLSAE 555
Query: 273 QDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQE---QEKGFR 329
+D LSG + A L AQS + E+ L +R +E+ +L RL E QE+G R
Sbjct: 556 KDALSGAVRQRE--ADLLAAQSLVRETEAALSREQQRSSQEQGELQGRLAERESQEQGLR 613
>gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens]
Length = 1048
Score = 49.3 bits (116), Expect = 5e-06
Identities = 63/243 (25%), Positives = 104/243 (42%), Gaps = 31/243 (12%)
Query: 24 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQ 83
E+ R+ QK D LR + + L R AQ E E QG EA+ S +
Sbjct: 374 ELEEQRKQKQKALVDNEQLRHELAQL---------RAAQLEGERSQGLREEAERKASATE 424
Query: 84 KLLLSELDMKKLRDRVQHLQNELIRKN-DREKELLLLYQAQQPQAALLKQYQGKLQKMKA 142
+K+ + H+ EL+RKN D K+L + Q+Q+ A + +Q +++++K
Sbjct: 425 ARYNK---LKEKHSELVHVHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQVEQVKR 481
Query: 143 LEETVRHQEK--VIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGE 200
E ++ +EK +EK++R LE + + ++ Q+ +T S L S +
Sbjct: 482 -ESELKLEEKSDQLEKLKRELEAKAGELAR-----AQEALSHT-----EQSKSELSSRLD 530
Query: 201 NLPVE---LYSVLLAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQE 257
L E L + A L R +A + +QQ + GEL G L ER +
Sbjct: 531 TLSAEKDALSGAVRQREADLLAAQSLVRETEAALSREQQRSSQEQGEL--QGRLAERESQ 588
Query: 258 THG 260
G
Sbjct: 589 EQG 591
Score = 33.1 bits (74), Expect = 0.41
Identities = 48/240 (20%), Positives = 95/240 (39%), Gaps = 13/240 (5%)
Query: 94 KLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKV 153
+L+ +V L+ EL + ++++ L+ + + + A L+ Q + ++ + L E +
Sbjct: 363 QLKSQVNALEGELEEQRKQKQKALVDNEQLRHELAQLRAAQLEGERSQGLREEAERKASA 422
Query: 154 IEKMERVLEDRLQDRSKP-PPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLA 212
E L+++ + L R+ + S + + E L ++ V
Sbjct: 423 TEARYNKLKEKHSELVHVHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQVEQVKRE 482
Query: 213 ENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQETHGPGHSECTETLPA 272
KL + D+ + ++ L GEL + +++ S
Sbjct: 483 SELKLEEKSDQ-------LEKLKRELEAKAGELARAQEALSHTEQSKSELSSRLDTLSAE 535
Query: 273 QDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQE---QEKGFR 329
+D LSG + A L AQS + E+ L +R +E+ +L RL E QE+G R
Sbjct: 536 KDALSGAVRQRE--ADLLAAQSLVRETEAALSREQQRSSQEQGELQGRLAERESQEQGLR 593
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 47.8 bits (112), Expect = 2e-05
Identities = 74/341 (21%), Positives = 148/341 (43%), Gaps = 56/341 (16%)
Query: 23 SEMNNYRRAMQKMAE--DILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVS 80
+E+ R ++++ + ++L+ R S + +R +L Q+E E+ QG++ E + V+
Sbjct: 787 AELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVA 846
Query: 81 MKQKLL--------LSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQ 132
Q+ + ++ +KK ++ L+ L+ EKE + +A + + L+
Sbjct: 847 QLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENE---LEA 903
Query: 133 YQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASG 192
QG L +T + Q+++ EK++ E + Q R + ++
Sbjct: 904 AQGN------LSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWH------------ 945
Query: 193 LPLGSMGENLPVELYSVLLAENA---KLRTELD----KNRHQQAPI--ILQQQALPVDPG 243
LG E L E+ ++ A +L+ +LD KNR + A + L+++ L +
Sbjct: 946 --LGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKS 1003
Query: 244 ELGAGGDLTE-RLQETHGPGHSEC-TETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLES 301
L A E RL E + E L + LL T L LE+ L +S
Sbjct: 1004 RLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQT------LKDLEYE----LEAKS 1053
Query: 302 QLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPVS 342
L+D R ++ +D ++L+ + + R +NS ++ + +S
Sbjct: 1054 HLKDDRSRLVKQMEDKVSQLEMELEEER--NNSDLLSERIS 1092
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 47.4 bits (111), Expect = 2e-05
Identities = 73/343 (21%), Positives = 143/343 (41%), Gaps = 50/343 (14%)
Query: 18 LIDSFSEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQN 77
L++ +E+N ++ +D+ + + +LE E + L+ +++ EEE+ Q
Sbjct: 1926 LMNQLAELNG---SIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQ-------- 1974
Query: 78 TVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKL 137
+K+K + K+ +++Q Q E K+ ++ LL + QQ L K
Sbjct: 1975 --LVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQ 2032
Query: 138 QKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGS 197
+K+ ALE TV+ E V + ++ LE ++ ++ ++ F +L
Sbjct: 2033 EKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLL-------- 2084
Query: 198 MGENLPVELYSVLLAENAKLRTELDKNRH------QQAPIILQQQALPVDPGELGAGGDL 251
++ E V LA+N KL+ EL N+ +Q L+++ + L ++
Sbjct: 2085 --DDTQSEAARV-LADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNM 2141
Query: 252 TER----------LQETHGPGHSECTETL-----PAQDLLSGTSDKFNLLAKLEHAQSRI 296
E+ L+ET G E TL Q L LA + S +
Sbjct: 2142 QEKLDALRREKVHLEETIG----EIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSL 2197
Query: 297 LSLESQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQ 339
++ D A++W R+ D A + +E+E + + S++ +Q
Sbjct: 2198 QDDRDRVIDEAKKWERKFSD-AIQSKEEEIRLKEDNCSVLKDQ 2239
Score = 38.9 bits (89), Expect = 0.007
Identities = 51/204 (25%), Positives = 86/204 (42%), Gaps = 18/204 (8%)
Query: 29 RRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLS 88
+ A +K+ E L+++ L + I+R+ EE A A++ V M+QKLL+
Sbjct: 2667 KEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERV----AELARDLVEMEQKLLMV 2722
Query: 89 ELDMKKLRDRVQ-------HLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMK 141
+ K L ++Q LQN N+ EL Y A + A LK+ QG L + +
Sbjct: 2723 TKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE-QGLLNRER 2781
Query: 142 --ALEETV----RHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPL 195
L ET +E + +E++ + L + L+ Q Y S + L
Sbjct: 2782 DALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASL 2841
Query: 196 GSMGENLPVELYSVLLAENAKLRT 219
+ ++L EL +E K R+
Sbjct: 2842 QNERDHLWNELEKFRKSEEGKQRS 2865
Score = 37.7 bits (86), Expect = 0.016
Identities = 84/378 (22%), Positives = 145/378 (38%), Gaps = 70/378 (18%)
Query: 24 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQ 83
++ + ++ A+ + L+++ + E N+IL +L Q E E + +NTV ++
Sbjct: 260 KLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEH-----NTLRNTVETER 314
Query: 84 ---KLLLS--ELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQ 138
K+LL EL++ + + +LQ E+ L QA Q QA L +Y Q
Sbjct: 315 EESKILLEKMELEVAERKLSFHNLQEEM------HHLLEQFEQAGQAQAELESRYSALEQ 368
Query: 139 KMKA-LEETVRH-----------------------------QEKVIEKMERV--LEDRLQ 166
K KA +EE H E+ ++ + + LED+LQ
Sbjct: 369 KHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQ 428
Query: 167 DRSKP-------PPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAK--- 216
+SK PL + + T FP + G EN+ V+ EN K
Sbjct: 429 QKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQ-AVTEENIASLQKRVVELENEKGAL 487
Query: 217 --LRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTE-RLQETHGPGHSECTETLPAQ 273
EL++ + + + Q L A +++E + + S E+ Q
Sbjct: 488 LLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEES--GQ 545
Query: 274 DLLSGTSDKFN-----LLAKLEHAQSRILSLESQLEDS-ARRWGREKQDLATRLQEQEKG 327
D+L T + + LL +++ AQ I L+ QL+ A E D Q + +G
Sbjct: 546 DVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEG 605
Query: 328 FRHPSNSIIIEQPVSDPP 345
+ +E D P
Sbjct: 606 IAPIKMKVFLEDTGQDFP 623
Score = 34.3 bits (77), Expect = 0.18
Identities = 72/333 (21%), Positives = 125/333 (37%), Gaps = 47/333 (14%)
Query: 18 LIDSFSEMNNYRRAMQKMAEDILSLRRQA----SILEGENRILRSRLAQQEEEEGQGKAS 73
L+ S+ ++N +Q + E + +++ E + +L + E+E + K
Sbjct: 1618 LLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEK 1677
Query: 74 EAQNTVSMKQKLLLSELDMKKLR-------DRVQHLQNELIRKNDREKELLLLYQAQQPQ 126
+ S +QK+L E + +LR D + L+ N KE L + +
Sbjct: 1678 MRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKE--ELERVKMEY 1735
Query: 127 AALLKQYQGKLQKMKALEETV---RHQ-EKVIEKMERVLEDRLQDRSKPPPLNRQQGKPY 182
L K++Q + + +L E V +HQ E + K + D Q P
Sbjct: 1736 ETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPG 1795
Query: 183 TGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPVDP 242
S S + E++P A++A D + H + LQQ +D
Sbjct: 1796 ETEEQDSLSMSTRPTCSESVP-------SAKSANPAVSKDFSSHDEINNYLQQ----ID- 1843
Query: 243 GELGAGGDLTERLQ--ETHGPGHSECTETLPAQ--DLLSGTSDKFNLLAKLEHAQSRILS 298
L ER+ E + E ++TL + LLS S K L L+ +++
Sbjct: 1844 -------QLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNL 1896
Query: 299 LESQLEDSARRWGR-------EKQDLATRLQEQ 324
L Q+++ R + EK DL RL Q
Sbjct: 1897 LNQQIQEELSRVTKLKETAEEEKDDLEERLMNQ 1929
Score = 33.5 bits (75), Expect = 0.31
Identities = 68/341 (19%), Positives = 134/341 (39%), Gaps = 47/341 (13%)
Query: 24 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEE--------EGQGKASEA 75
E+ + + K +I SL+ + E L+ +L + + E Q K E
Sbjct: 1338 EVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDEL 1397
Query: 76 QNTVSMKQK---LLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQA-ALLK 131
Q +S K++ L +L K+ + +Q E+I + D K L + Q + +K
Sbjct: 1398 QKLISKKEEDVSYLSGQLSEKEAA--LTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIK 1455
Query: 132 QYQGKLQKMKALEETVRHQEKVIEKMERVLEDRL--------QDRSKPPPLNRQQGKPYT 183
Q Q +L +MK E + + + ++++R L+ L +++S L+ +G
Sbjct: 1456 QLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIER 1515
Query: 184 GFPMLSASGLPLGSMGENLPVEL--YSVLLAENAKLRTELDKNRHQQAPIILQQQALPVD 241
L+ + + + L ++L E KL TE+D++ +L+ Q+L
Sbjct: 1516 LTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRS-------LLENQSLSSS 1568
Query: 242 PGEL-----GAGGDLTERLQETHGPGHSECTETLPAQD-----------LLSGTSDKFNL 285
L G D + ++E S+ E+ Q+ LL + N
Sbjct: 1569 CESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNE 1628
Query: 286 LAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQEK 326
+++H + + +L R K++ +LQE E+
Sbjct: 1629 AERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQ 1669
Score = 32.0 bits (71), Expect = 0.90
Identities = 32/144 (22%), Positives = 59/144 (40%), Gaps = 5/144 (3%)
Query: 32 MQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELD 91
+ + + SL+ + G+ + L R E+ Q A +K+++
Sbjct: 2459 LDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSH 2518
Query: 92 MKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGK--LQKMKALEETVRH 149
M L L ELI+ + +++ + +QQ Q ++ Q K K LEE ++
Sbjct: 2519 MDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKE 2578
Query: 150 QEKVIEKMER---VLEDRLQDRSK 170
E+ E + R L++ QD SK
Sbjct: 2579 SEEANEDLRRSFNALQEEKQDLSK 2602
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 46.6 bits (109), Expect = 4e-05
Identities = 75/331 (22%), Positives = 141/331 (42%), Gaps = 41/331 (12%)
Query: 32 MQKMAEDILSLRRQASILEGENRILRSRLA----QQEEEEGQGKASEAQNTVSMKQKLLL 87
M+K ED+L L Q S L E ++L RLA Q EEE + K + N + +K + +
Sbjct: 1005 MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVK---SLNKLRLKYEATI 1061
Query: 88 SEL------------DMKKLRDRV----QHLQNELIRKNDREKEL-LLLYQAQQPQAALL 130
+++ +++KL+ R+ LQ +++ + R +EL L + ++ A L
Sbjct: 1062 ADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAAL 1121
Query: 131 KQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSA 190
+ + + L +++R + + + + LE R+K R G+
Sbjct: 1122 ARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELE 1181
Query: 191 SGLPLGSMGENLPVELYSVLLAENAKLRTELDKNR--HQQAPIILQQQALPVDPGELGAG 248
L N EL S E +L+ L++ H+ A L+Q+ G+ A
Sbjct: 1182 DTLD----STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQR-----HGQ--AL 1230
Query: 249 GDLTERLQET-HGPGHSECTETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSA 307
G+L E+L++ G G E T ++ ++ +L + + R LE QL++
Sbjct: 1231 GELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQ 1290
Query: 308 RRWG---REKQDLATRLQEQEKGFRHPSNSI 335
R G R + + A +LQ + + S ++
Sbjct: 1291 GRAGDGERARAEAAEKLQRAQAELENVSGAL 1321
Score = 37.4 bits (85), Expect = 0.021
Identities = 41/149 (27%), Positives = 73/149 (48%), Gaps = 11/149 (7%)
Query: 24 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQ--GKASEAQNTVSM 81
E+ + Q+ A ++ L+ + + LE E R+RLA+Q E + +A E + ++
Sbjct: 885 ELQKVQELQQQSAREVGELQGRVAQLEEE----RARLAEQLRAEAELCAEAEETRGRLAA 940
Query: 82 KQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMK 141
+++ L EL + +L RV + E R+ EK+ L Q Q A L+ +G QK++
Sbjct: 941 RKQEL--ELVVSELEARVGE-EEECSRQMQTEKKRL--QQHIQELEAHLEAEEGARQKLQ 995
Query: 142 ALEETVRHQEKVIEKMERVLEDRLQDRSK 170
+ T + K E+ +LED+ SK
Sbjct: 996 LEKVTTEAKMKKFEEDLLLLEDQNSKLSK 1024
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 46.6 bits (109), Expect = 4e-05
Identities = 75/331 (22%), Positives = 141/331 (42%), Gaps = 41/331 (12%)
Query: 32 MQKMAEDILSLRRQASILEGENRILRSRLA----QQEEEEGQGKASEAQNTVSMKQKLLL 87
M+K ED+L L Q S L E ++L RLA Q EEE + K + N + +K + +
Sbjct: 997 MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVK---SLNKLRLKYEATI 1053
Query: 88 SEL------------DMKKLRDRV----QHLQNELIRKNDREKEL-LLLYQAQQPQAALL 130
+++ +++KL+ R+ LQ +++ + R +EL L + ++ A L
Sbjct: 1054 ADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAAL 1113
Query: 131 KQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSA 190
+ + + L +++R + + + + LE R+K R G+
Sbjct: 1114 ARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELE 1173
Query: 191 SGLPLGSMGENLPVELYSVLLAENAKLRTELDKNR--HQQAPIILQQQALPVDPGELGAG 248
L N EL S E +L+ L++ H+ A L+Q+ G+ A
Sbjct: 1174 DTLD----STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQR-----HGQ--AL 1222
Query: 249 GDLTERLQET-HGPGHSECTETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSA 307
G+L E+L++ G G E T ++ ++ +L + + R LE QL++
Sbjct: 1223 GELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQ 1282
Query: 308 RRWG---REKQDLATRLQEQEKGFRHPSNSI 335
R G R + + A +LQ + + S ++
Sbjct: 1283 GRAGDGERARAEAAEKLQRAQAELENVSGAL 1313
Score = 37.4 bits (85), Expect = 0.021
Identities = 41/149 (27%), Positives = 73/149 (48%), Gaps = 11/149 (7%)
Query: 24 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQ--GKASEAQNTVSM 81
E+ + Q+ A ++ L+ + + LE E R+RLA+Q E + +A E + ++
Sbjct: 877 ELQKVQELQQQSAREVGELQGRVAQLEEE----RARLAEQLRAEAELCAEAEETRGRLAA 932
Query: 82 KQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMK 141
+++ L EL + +L RV + E R+ EK+ L Q Q A L+ +G QK++
Sbjct: 933 RKQEL--ELVVSELEARVGE-EEECSRQMQTEKKRL--QQHIQELEAHLEAEEGARQKLQ 987
Query: 142 ALEETVRHQEKVIEKMERVLEDRLQDRSK 170
+ T + K E+ +LED+ SK
Sbjct: 988 LEKVTTEAKMKKFEEDLLLLEDQNSKLSK 1016
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 46.6 bits (109), Expect = 4e-05
Identities = 75/331 (22%), Positives = 141/331 (42%), Gaps = 41/331 (12%)
Query: 32 MQKMAEDILSLRRQASILEGENRILRSRLA----QQEEEEGQGKASEAQNTVSMKQKLLL 87
M+K ED+L L Q S L E ++L RLA Q EEE + K + N + +K + +
Sbjct: 1038 MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVK---SLNKLRLKYEATI 1094
Query: 88 SEL------------DMKKLRDRV----QHLQNELIRKNDREKEL-LLLYQAQQPQAALL 130
+++ +++KL+ R+ LQ +++ + R +EL L + ++ A L
Sbjct: 1095 ADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAAL 1154
Query: 131 KQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSA 190
+ + + L +++R + + + + LE R+K R G+
Sbjct: 1155 ARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELE 1214
Query: 191 SGLPLGSMGENLPVELYSVLLAENAKLRTELDKNR--HQQAPIILQQQALPVDPGELGAG 248
L N EL S E +L+ L++ H+ A L+Q+ G+ A
Sbjct: 1215 DTLD----STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQR-----HGQ--AL 1263
Query: 249 GDLTERLQET-HGPGHSECTETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSA 307
G+L E+L++ G G E T ++ ++ +L + + R LE QL++
Sbjct: 1264 GELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQ 1323
Query: 308 RRWG---REKQDLATRLQEQEKGFRHPSNSI 335
R G R + + A +LQ + + S ++
Sbjct: 1324 GRAGDGERARAEAAEKLQRAQAELENVSGAL 1354
Score = 37.4 bits (85), Expect = 0.021
Identities = 41/149 (27%), Positives = 73/149 (48%), Gaps = 11/149 (7%)
Query: 24 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQ--GKASEAQNTVSM 81
E+ + Q+ A ++ L+ + + LE E R+RLA+Q E + +A E + ++
Sbjct: 918 ELQKVQELQQQSAREVGELQGRVAQLEEE----RARLAEQLRAEAELCAEAEETRGRLAA 973
Query: 82 KQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMK 141
+++ L EL + +L RV + E R+ EK+ L Q Q A L+ +G QK++
Sbjct: 974 RKQEL--ELVVSELEARVGE-EEECSRQMQTEKKRL--QQHIQELEAHLEAEEGARQKLQ 1028
Query: 142 ALEETVRHQEKVIEKMERVLEDRLQDRSK 170
+ T + K E+ +LED+ SK
Sbjct: 1029 LEKVTTEAKMKKFEEDLLLLEDQNSKLSK 1057
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 46.2 bits (108), Expect = 5e-05
Identities = 40/144 (27%), Positives = 78/144 (54%), Gaps = 26/144 (18%)
Query: 32 MQKMAEDI-LSLRRQASILEGENRILRSRLAQQEEEEG-QGKASEAQNTVSMKQKLLLSE 89
++K +D+ + L QA ++G+ L ++L + +EEEG Q KA EAQN + K+K
Sbjct: 1221 LEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEK----- 1275
Query: 90 LDMKKLRDRVQHLQ---NELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEET 146
+KL D++Q +Q + L ++ + E E+ ++ + + L + + LEE
Sbjct: 1276 ---EKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTL---------ENRDLEEE 1323
Query: 147 VRHQEKVIEKMERVLEDRLQDRSK 170
+ +++VI+K L+D+++ SK
Sbjct: 1324 LDMKDRVIKK----LQDQVKTLSK 1343
>gi|65301130 kazrin isoform B [Homo sapiens]
Length = 415
Score = 46.2 bits (108), Expect = 5e-05
Identities = 41/174 (23%), Positives = 81/174 (46%), Gaps = 12/174 (6%)
Query: 5 GPPSPPAPKAAPGLIDSFSEMNNYRRAMQKMAED-----ILSLRRQASILEGENRILR-- 57
GP PP P A +D+ + R + ++ D + LR + S L+ E +LR
Sbjct: 30 GPARPPGPAACEQCVDAAGPGDRPRAGVPRVRADGDCSQPVLLREEVSRLQEEVHLLRQM 89
Query: 58 -SRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKEL 116
LA+ EE GK+SE + ++ +L E ++ + ++ +Q ++ + RK + ++
Sbjct: 90 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKAD--RKRLKGEKT 147
Query: 117 LLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSK 170
L+ Q QQ A L + + ++ E+ + E ++ + + E L +R K
Sbjct: 148 DLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAK--EKDLLEREK 199
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 45.8 bits (107), Expect = 6e-05
Identities = 52/243 (21%), Positives = 113/243 (46%), Gaps = 20/243 (8%)
Query: 25 MNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEA--QNTVSMK 82
M+ ++ + ++ L++Q L+ + + L QQE+ + Q + + Q ++
Sbjct: 153 MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQ 212
Query: 83 QKLLLSE---LDMKKLRDRVQHLQNE----LIRKNDREKELLLLYQAQQPQAALLKQYQG 135
Q+ LL + L ++ + + + LQ + L+++ + ++ LL Q Q Q LL+Q Q
Sbjct: 213 QQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQA 272
Query: 136 KLQKMKALEETVRHQEKVIEKMERVLEDRLQDRS-KPPPLNRQQGK--PYTGFPMLSASG 192
+LQ+ L++ + Q++ +++ + +++LQ + +PPPL ++ + P+ S
Sbjct: 273 QLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSE 332
Query: 193 LPLGSMGENLPVELYSVLLAENAKLRTELDKN--------RHQQAPIILQQQALPVDPGE 244
L + L + E +L+ +L + QQ + Q+ L + P E
Sbjct: 333 QELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVE 392
Query: 245 LGA 247
LGA
Sbjct: 393 LGA 395
Score = 40.4 bits (93), Expect = 0.003
Identities = 48/247 (19%), Positives = 99/247 (40%), Gaps = 9/247 (3%)
Query: 3 EPGPPSPPAPKAAPGLIDSFSEMNNYRRAMQKMAEDILSLRRQASILE----GENRILRS 58
E G P P G +S E R + + + I E G+ +
Sbjct: 33 EDGGPGPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQ 92
Query: 59 RLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLL 118
+L QQ E + Q + + Q + + D ++ ++Q +++ + + + EL L
Sbjct: 93 QLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQL 152
Query: 119 LYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQ 178
++Q QQ Q +++ Q +LQ+ + +T + QE+ + + + L+ ++Q++ Q
Sbjct: 153 MHQQQQLQPQQVQEQQ-RLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQL 211
Query: 179 GKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQAL 238
+ E L + +LL + +L+ +L + + Q LQQQ L
Sbjct: 212 QQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQ----LQQQLL 267
Query: 239 PVDPGEL 245
+L
Sbjct: 268 EQQQAQL 274
>gi|19923830 pre-B-cell leukemia homeobox interacting protein 1
[Homo sapiens]
Length = 731
Score = 45.8 bits (107), Expect = 6e-05
Identities = 45/174 (25%), Positives = 83/174 (47%), Gaps = 19/174 (10%)
Query: 15 APGLIDSFSEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQ---EEEEGQGK 71
AP DS + N + K+A++ +R + L+ + L+S + Q EEE Q +
Sbjct: 255 APVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLR 314
Query: 72 ASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDR---------EKELLLLYQA 122
+ Q Q+ L SEL ++LR R+Q L+ + +R D + + + Q
Sbjct: 315 GALQQGEAF--QRALESEL--QQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQG 370
Query: 123 ---QQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPP 173
Q+P+ + LKQ + + +AL + + Q +++ +++ LE LQD S+ P
Sbjct: 371 PREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDP 424
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 45.4 bits (106), Expect = 8e-05
Identities = 64/298 (21%), Positives = 120/298 (40%), Gaps = 28/298 (9%)
Query: 33 QKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDM 92
Q+ E L+ + S+LE + + L +L EEE + S+ + T +Q LL +
Sbjct: 1023 QRAQEHSSRLQAEKSVLEIQGQELHRKLEVLEEEVRAARQSQ-EETRGQQQALLRDHKAL 1081
Query: 93 KKLRDRVQ-HLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQE 151
+L+ R + L+ L+R D + + L A ++ QG+ ++++A +V QE
Sbjct: 1082 AQLQRRQEAELEGLLVRHRDLKANMRALELAH-------RELQGRHEQLQAQRASVEAQE 1134
Query: 152 -KVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVL 210
++ + ER+++D + R L R Q + +L+ G L
Sbjct: 1135 VALLAERERLMQDGHRQRGLEEELRRLQSEHDRAQMLLAELSRERGE------------L 1182
Query: 211 LAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGG----DLTERLQETHGPGHSEC 266
E +LR L + ++A + +Q Q L +L E L + E
Sbjct: 1183 QGERGELRGRLARLELERAQLEMQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEEN 1242
Query: 267 TETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQ 324
+ L LS + LL + ++ + + + D REKQ L ++ +Q
Sbjct: 1243 RQLLAEVQALS--RENRELLERSLESRDHLHREQREYLDQLNALRREKQKLVEKIMDQ 1298
Score = 40.4 bits (93), Expect = 0.003
Identities = 59/282 (20%), Positives = 114/282 (40%), Gaps = 16/282 (5%)
Query: 37 EDILSLRRQASILEGENRILR---SRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMK 93
E ++ L+ +A LE E LR + L ++ E Q ++ + +++ + +
Sbjct: 936 EALMELKTRALQLEEELFQLRQGPAGLGPKKRAEPQLVETQNVRLIEVERSNAMLVAEKA 995
Query: 94 KLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQ--------KMKALEE 145
L+ ++QHL+ +L R +ELLL Q Q ++ L+ + L+ K++ LEE
Sbjct: 996 ALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSVLEIQGQELHRKLEVLEE 1055
Query: 146 TVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVE 205
VR + E+ + L+D L R+Q G ++ L L
Sbjct: 1056 EVRAARQSQEETRGQQQALLRDHKALAQLQRRQEAELEGL-LVRHRDLKANMRALEL--- 1111
Query: 206 LYSVLLAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQETHGPGHSE 265
+ L + +L+ + Q+ ++ +++ L D + RLQ H
Sbjct: 1112 AHRELQGRHEQLQAQRASVEAQEVALLAERERLMQDGHRQRGLEEELRRLQSEHDRAQML 1171
Query: 266 CTETLPAQDLLSGTSDKF-NLLAKLEHAQSRILSLESQLEDS 306
E + L G + LA+LE ++++ QL +S
Sbjct: 1172 LAELSRERGELQGERGELRGRLARLELERAQLEMQSQQLRES 1213
Score = 38.1 bits (87), Expect = 0.013
Identities = 60/257 (23%), Positives = 105/257 (40%), Gaps = 49/257 (19%)
Query: 6 PPSPPAPKAAPGLIDSFSEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEE 65
P P+ A L ++ +++ R+ +++ AE +L + + LE E R LR + +
Sbjct: 248 PAEGPSHHLALQLANAKAQLRRLRQELEEKAELLLDSQAEVQGLEAEIRRLRQ---EAQA 304
Query: 66 EEGQGKASE-----AQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLY 120
GQ K +E A+ +L + ++++ R+R+Q + K+ E+E +L
Sbjct: 305 LSGQAKRAELYREEAEALRERAGRLPRLQEELRRCRERLQAAE---AYKSQLEEERVLSG 361
Query: 121 QAQQPQAALLKQYQGKLQKMKALEET--------------------VRHQEKVIEKMERV 160
+ +A L +Q + ++ L ET +RHQ + +
Sbjct: 362 VLEASKALLEEQLEAARERCARLHETQRENLLLRTRLGEAHAELDSLRHQVDQLAEENVE 421
Query: 161 LEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTE 220
LE LQ +PPP G P PL +L E V AE +LRT
Sbjct: 422 LELELQRSLEPPP-----GSP---------GEAPLAGAAPSLQDE---VREAEAGRLRTL 464
Query: 221 LDKNRHQQAPI-ILQQQ 236
+NR + + +LQ Q
Sbjct: 465 ERENRELRGLLQVLQGQ 481
Score = 32.3 bits (72), Expect = 0.69
Identities = 44/157 (28%), Positives = 75/157 (47%), Gaps = 20/157 (12%)
Query: 26 NNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKL 85
+ + RA +AE L R+ L+GE LR RLA+ E E Q ++Q Q+L
Sbjct: 1163 SEHDRAQMLLAE----LSRERGELQGERGELRGRLARLELERAQ-LEMQSQQLRESNQQL 1217
Query: 86 LLSELDMK---KLRDRVQHLQNELIRKNDREKELL------LLYQAQQPQAALLKQYQGK 136
LS + +L +++ Q E R+ E + L LL ++ + + L ++ +
Sbjct: 1218 DLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLESRDHLHREQREY 1277
Query: 137 LQKMKALEETVRHQEKVIEKM---ERVLEDRLQDRSK 170
L ++ AL R ++K++EK+ RVLE R+K
Sbjct: 1278 LDQLNALR---REKQKLVEKIMDQYRVLEPVPLPRTK 1311
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 45.4 bits (106), Expect = 8e-05
Identities = 79/339 (23%), Positives = 135/339 (39%), Gaps = 53/339 (15%)
Query: 22 FSEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQE------EEEGQGKASEA 75
+ E R AE I RQ L E R L+ R + E E E Q +
Sbjct: 1358 YEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEELERERQARREAE 1417
Query: 76 QNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQG 135
+ ++Q+L E + + R++V H Q +++++ ++ L + Q L++ Q
Sbjct: 1418 REVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQ------LEEEQH 1471
Query: 136 KLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPL 195
+ Q ++ ET+R + +EK E V E + S + ++G L +S
Sbjct: 1472 RRQLLEGELETLRRKLAALEKAE-VKEKVVLSES----VQVEKGDTEQEIQRLKSSLEEE 1526
Query: 196 GSMGENLPVEL------YSVLLAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGG 249
L VE+ S L N+K ELD R + + L++Q L ++
Sbjct: 1527 SRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLE-------- 1578
Query: 250 DLTERLQETHGPGHSECTETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARR 309
T RLQ +E + SGT+ SR+ SLE +L+D +R
Sbjct: 1579 --TRRLQSEINMAATETRDLRNMTVADSGTNH-----------DSRLWSLERELDD-LKR 1624
Query: 310 WGREK----QDLATRL----QEQEKGFRHPSNSIIIEQP 340
++K +L RL ++E+ H SI++ P
Sbjct: 1625 LSKDKDLEIDELQKRLGSVAVKREQRENHLRRSIVVIHP 1663
Score = 35.0 bits (79), Expect = 0.11
Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 17/123 (13%)
Query: 34 KMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMK 93
++ E++ +LRRQ E E +L+ R+A EE+ S AQ V+ K+ + L +
Sbjct: 1012 QLREELEALRRQKGAREAEVLLLQQRVAALAEEK-----SRAQEKVTEKEVVKLQ--NDP 1064
Query: 94 KLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEE---TVRHQ 150
+L Q LQ + R++ L + Q+ + + L+ +L+K +A+ E TV+
Sbjct: 1065 QLEAEYQQLQEDHQRQDQ-------LREKQEEELSFLQDKLKRLEKERAMAEGKITVKEV 1117
Query: 151 EKV 153
KV
Sbjct: 1118 LKV 1120
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 45.1 bits (105), Expect = 1e-04
Identities = 60/291 (20%), Positives = 115/291 (39%), Gaps = 31/291 (10%)
Query: 49 LEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIR 108
+E + + ++ +EE + + V ++++ + ++D+K+ + +++HL R
Sbjct: 705 IEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKER 764
Query: 109 KNDREKELLLLYQAQQPQAALLKQYQGKLQ-----KMKALEETVRHQEKVIEKMERVLED 163
D K L L + Q+ LL Q + K Q +K LE+ ++ + + + +R+LE
Sbjct: 765 MEDEVKNLTLQLE-QESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEF 823
Query: 164 RLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELY-SVLLAENAK-LRTEL 221
L +K N Q + + + L E Y S L K L+ E+
Sbjct: 824 ELAQLTKQYRGNEGQ----------------MRELQDQLEAEQYFSTLYKTQVKELKEEI 867
Query: 222 -DKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQETHGPGHSECTETL--PAQDLLSG 278
+KNR I Q L + L DL E E+ E Q+
Sbjct: 868 EEKNRENLKKI----QELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKA 923
Query: 279 TSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQEKGFR 329
S + +H SR+ S L RE ++L ++++ E+ ++
Sbjct: 924 ASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYK 974
Score = 32.7 bits (73), Expect = 0.53
Identities = 29/141 (20%), Positives = 66/141 (46%), Gaps = 2/141 (1%)
Query: 24 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQ 83
E+ + + ++ E L + IL EN L ++ + EEE K E N + +
Sbjct: 930 EITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFE 989
Query: 84 KLLLSELDMK-KLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKA 142
K + +E +K + +++ + N K DR+K + ++ + L Q + ++ K
Sbjct: 990 KNINTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKKEKENRKL-QLELNQEREKF 1048
Query: 143 LEETVRHQEKVIEKMERVLED 163
+ V+HQ+++ + +++E+
Sbjct: 1049 NQMVVKHQKELNDMQAQLVEE 1069
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 44.7 bits (104), Expect = 1e-04
Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 8/126 (6%)
Query: 59 RLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLL 118
RLA+ E+ E Q E + + + K LL ++ L++ + + EL ++EK++
Sbjct: 197 RLAESEKSEIQLNVKELKRKLE-RAKFLLPQVQTNTLQEEMWRQEEEL---REQEKKIRK 252
Query: 119 LYQAQQPQAALLKQYQGKL----QKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPL 174
+ Q L++ +GK+ +KM+ E+ +R QEK + + E+ L ++ + R + +
Sbjct: 253 QEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQM 312
Query: 175 NRQQGK 180
Q+ K
Sbjct: 313 QEQEEK 318
Score = 41.2 bits (95), Expect = 0.001
Identities = 38/166 (22%), Positives = 78/166 (46%), Gaps = 17/166 (10%)
Query: 29 RRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMK-----Q 83
RR +++ E LR Q L + ++ QE+EE + E K +
Sbjct: 279 RRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338
Query: 84 KLLLSELDMK----KLRDRVQHL--QNELIRKND---REKELLLLYQAQQPQAALLKQYQ 134
+L E M+ K+RD+ + + Q+E +R+ + RE+E + + + + +++ +
Sbjct: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRERE 398
Query: 135 GKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGK 180
+KM+ EET+R QE+ ++K E + ++ + + L Q+ K
Sbjct: 399 ---KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441
Score = 38.1 bits (87), Expect = 0.013
Identities = 61/305 (20%), Positives = 125/305 (40%), Gaps = 56/305 (18%)
Query: 29 RRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLS 88
R +KM LR Q L + + LR + +E+EE + E K+
Sbjct: 272 REQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEE---------KMWEQ 322
Query: 89 ELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVR 148
E +K+R++ + + + R ++EK++ Q + Q + + ++++ EE +R
Sbjct: 323 E---EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD---ERLREKEERMR 376
Query: 149 HQEKVIEKMERVL-EDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELY 207
QEK+ E+ E++ E+R+++R K M E
Sbjct: 377 EQEKMWEQEEKMQEEERIREREK--------------------------KMREE------ 404
Query: 208 SVLLAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQETHGPGHSECT 267
+ E + + ++N +Q QQQ LP +L + E+ ++ E
Sbjct: 405 EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW-----EQE 459
Query: 268 ETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARR-WGREKQ--DLATRLQEQ 324
E + Q+ + G K K+ + ++ E ++ D ++ W +E++ + RL+E+
Sbjct: 460 EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK 519
Query: 325 EKGFR 329
E+ R
Sbjct: 520 EERMR 524
Score = 34.7 bits (78), Expect = 0.14
Identities = 62/288 (21%), Positives = 119/288 (41%), Gaps = 45/288 (15%)
Query: 43 RRQASILEGENRILRS--RLAQQEEE--EGQGKASEAQNTVSMKQKLLLSELDMKKLRDR 98
R++ + E E +I + ++ +QEE E +GK E + + ++K L + K+LR++
Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQ--EKELREQ 295
Query: 99 VQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKME 158
+ L+ + K RE+E Q Q+ + + +Q + KM+ EE + QE E
Sbjct: 296 EKELREQ---KKLREQE----EQMQEQEEKMWEQEE----KMREQEEKMWRQE------E 338
Query: 159 RVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLR 218
R+ E Q R + + Q+ + + L M E + + E ++R
Sbjct: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKE---ERMREQEKMWEQEEKMQEEERIR 395
Query: 219 TELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQETHGPGHSECTETLPAQDLLSG 278
K R ++ + Q+ E++Q+ E E Q L
Sbjct: 396 EREKKMREEEETMREQE-----------------EKMQKQE-ENMWEQEEKEWQQQRLPE 437
Query: 279 TSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQD-LATRLQEQE 325
+K K++ + +I E ++ D WG+EK+ +++EQE
Sbjct: 438 QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 485
Score = 34.3 bits (77), Expect = 0.18
Identities = 25/147 (17%), Positives = 72/147 (48%), Gaps = 9/147 (6%)
Query: 20 DSFSEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEE--EGQGKASEAQN 77
+ E R +KM E+ +R Q ++ + +R +QEE+ E + K E +
Sbjct: 554 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMR----EQEEKMWEQEEKMQEQEE 609
Query: 78 TVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKL 137
+ +++ + + + K++++ + + + + ++E+++ + + Q +++ +
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE--- 666
Query: 138 QKMKALEETVRHQEKVIEKMERVLEDR 164
+KM+ EE +R QE+ ++ E + ++
Sbjct: 667 EKMQGQEEKMREQEEKMQGQEEKMREQ 693
Score = 32.7 bits (73), Expect = 0.53
Identities = 31/152 (20%), Positives = 67/152 (44%), Gaps = 6/152 (3%)
Query: 33 QKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDM 92
+KM E+ R+ + E E + QE+EE + E ++K+ E M
Sbjct: 554 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM--WEQEEKMQEQEEKM 611
Query: 93 KKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEK 152
+ +++ + E +E+E ++ Q ++ Q K ++ + +KM+ EE +R QE+
Sbjct: 612 WEQEEKMWEQEEE---DKMQEQEEMMWEQEEKMQEQEEKMWEQE-EKMREQEEKMREQEE 667
Query: 153 VIEKMERVLEDRLQDRSKPPPLNRQQGKPYTG 184
++ E + ++ + R+Q + G
Sbjct: 668 KMQGQEEKMREQEEKMQGQEEKMREQEEKMRG 699
Score = 32.3 bits (72), Expect = 0.69
Identities = 31/162 (19%), Positives = 72/162 (44%), Gaps = 16/162 (9%)
Query: 24 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQ 83
+M M + E + + + E E + QE+EE + E ++
Sbjct: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR--EQEE 660
Query: 84 KLLLSELDMK----KLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQK 139
K+ E M+ K+R++ + +Q + + ++E+++ + Q+ ++ G+ +K
Sbjct: 661 KMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKM----RGQE------EKMWGQEEK 710
Query: 140 MKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKP 181
M EE + QE++ EK ER+ + + + + + P + +P
Sbjct: 711 MWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEP 752
Score = 32.0 bits (71), Expect = 0.90
Identities = 21/112 (18%), Positives = 56/112 (50%), Gaps = 11/112 (9%)
Query: 57 RSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKEL 116
+ ++ QQEE+ + K ++ Q + Q+ + E + + R++ + E++R+ + +
Sbjct: 526 QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK--- 582
Query: 117 LLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDR 168
Q Q +++ + K+ + + E+ +EK+ E+ E++ E +D+
Sbjct: 583 ------MQEQEEKMREQEEKMWEQE--EKMQEQEEKMWEQEEKMWEQEEEDK 626
Score = 30.0 bits (66), Expect = 3.4
Identities = 31/159 (19%), Positives = 72/159 (45%), Gaps = 5/159 (3%)
Query: 24 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASE---AQNTVS 80
E R +KM E ++ + I E E ++ +E+EE K E Q
Sbjct: 370 EKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 429
Query: 81 MKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKM 140
+Q+ L + + ++++Q + ++ + ++ ++ ++ Q+ + ++ + + +M
Sbjct: 430 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW-GQEKKMWRQEKMREQEDQM 488
Query: 141 KALEETVRHQE-KVIEKMERVLEDRLQDRSKPPPLNRQQ 178
EE +R QE K+ ++ ER+ E + R K + Q+
Sbjct: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQK 527
>gi|39930479 DIX domain containing 1 isoform b [Homo sapiens]
Length = 472
Score = 44.7 bits (104), Expect = 1e-04
Identities = 38/139 (27%), Positives = 70/139 (50%), Gaps = 19/139 (13%)
Query: 23 SEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMK 82
S ++ Q + +++L +++A L+G L+ RL QQ+ + + +K
Sbjct: 130 SRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQD-----------TSVLQLK 178
Query: 83 QKLLLSELDMKKLRDRVQHLQN-ELIRKNDREKELLLLYQAQQPQA-ALLKQYQGKLQK- 139
Q+LL + +D +L H QN +L RK D LL Y+ + Q LL+Q+Q KL++
Sbjct: 179 QELLRANMDKDEL-----HNQNVDLQRKLDERNRLLGEYKKELGQKDRLLQQHQAKLEEA 233
Query: 140 MKALEETVRHQEKVIEKME 158
++ L + HQ + ++E
Sbjct: 234 LRKLSDVSYHQVDLERELE 252
>gi|83816971 DIX domain containing 1 isoform a [Homo sapiens]
Length = 683
Score = 44.7 bits (104), Expect = 1e-04
Identities = 38/139 (27%), Positives = 70/139 (50%), Gaps = 19/139 (13%)
Query: 23 SEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMK 82
S ++ Q + +++L +++A L+G L+ RL QQ+ + + +K
Sbjct: 341 SRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQD-----------TSVLQLK 389
Query: 83 QKLLLSELDMKKLRDRVQHLQN-ELIRKNDREKELLLLYQAQQPQA-ALLKQYQGKLQK- 139
Q+LL + +D +L H QN +L RK D LL Y+ + Q LL+Q+Q KL++
Sbjct: 390 QELLRANMDKDEL-----HNQNVDLQRKLDERNRLLGEYKKELGQKDRLLQQHQAKLEEA 444
Query: 140 MKALEETVRHQEKVIEKME 158
++ L + HQ + ++E
Sbjct: 445 LRKLSDVSYHQVDLERELE 463
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 44.7 bits (104), Expect = 1e-04
Identities = 79/338 (23%), Positives = 135/338 (39%), Gaps = 63/338 (18%)
Query: 23 SEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQE-------------EEEGQ 69
+++ R M ++ ED++S RR++ + E E R SRLA +E + + Q
Sbjct: 559 AQVEEMRLMMNQLEEDLVSARRRSDLYESELR--ESRLAAEEFKRKATECQHKLLKAKDQ 616
Query: 70 GKASEAQ----NTVSMKQKLLLSELD------MKKLRDRVQHLQNELIRKNDREKELLLL 119
GK + ++ +Q+L + EL +K + + LQN K E+EL L
Sbjct: 617 GKPEVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKL 676
Query: 120 YQAQQPQAALLKQYQGKLQKMKALEETVR------------------HQEKVIEKMERVL 161
+ + K KL + + LEE R H E+ I+ ++ +
Sbjct: 677 QNREDSSEGIRK----KLVEAEELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQI 732
Query: 162 EDRLQDR-SKPPPLNRQQGKPYTGFPMLSASGLPLGSMG------ENLPVELYSV-LLAE 213
+ L D+ + + R + + + +LS + +M E VEL LA
Sbjct: 733 KKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAA 792
Query: 214 NAKLRTELDKNRHQQAPIILQQQA--LPVDPGELGA-GGDLTERLQETHGPGHSECTETL 270
N+ L T+ + ++ L+QQ L G+L A L E+L++ HS+ L
Sbjct: 793 NSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLL 852
Query: 271 PAQDLLSGTS-----DKFNLLAKLEHAQSRILSLESQL 303
+ L S K L +L Q + ESQL
Sbjct: 853 ELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQL 890
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/158 (21%), Positives = 74/158 (46%), Gaps = 13/158 (8%)
Query: 24 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQ 83
E R ++ ++ R++ I E E +I QE+EE G+ E ++
Sbjct: 368 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM--WEQEE 425
Query: 84 KLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQP----QAALLKQYQGKLQ- 138
++ E M++ ++++ + ++ + ++ +E + Q Q+ Q + + + K+Q
Sbjct: 426 EMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQE 485
Query: 139 ---KMKALEETVRHQEKVIEKME---RVLEDRLQDRSK 170
KM+ EE +R QEK I + E R E+ +Q++ +
Sbjct: 486 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 523
Score = 43.1 bits (100), Expect = 4e-04
Identities = 36/158 (22%), Positives = 78/158 (49%), Gaps = 7/158 (4%)
Query: 29 RRAMQKMAEDILSLRRQASIL---EGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKL 85
RR + M E +RRQ ++ E + R L ++ +QE+ Q + + + + ++K
Sbjct: 319 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 378
Query: 86 LLSELDMKKLRDRVQHLQNELIRKNDR--EKELLLLYQAQQPQAALLKQYQGKLQKMKAL 143
E M + ++++ Q E IR+ + +++ + + ++ ++ Q + +KM+
Sbjct: 379 QEQEAKMWRQEEKIRE-QEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQ 437
Query: 144 EETVRHQEKVI-EKMERVLEDRLQDRSKPPPLNRQQGK 180
EE +R QEK I E+ E++ E + + + Q+GK
Sbjct: 438 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGK 475
Score = 38.5 bits (88), Expect = 0.010
Identities = 27/144 (18%), Positives = 68/144 (47%), Gaps = 4/144 (2%)
Query: 24 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQ 83
EM M++ E I ++ E + R + +QEE+ G+ + + M++
Sbjct: 426 EMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQE 485
Query: 84 KLLLSELDMKKLRDRVQHL--QNELIRKNDR--EKELLLLYQAQQPQAALLKQYQGKLQK 139
+ +K+R++ + + Q E IR+ + +++ +++ ++ ++ Q + +K
Sbjct: 486 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 545
Query: 140 MKALEETVRHQEKVIEKMERVLED 163
M+ EE +R QE + + E +++
Sbjct: 546 MRRQEEKMREQEVRLRQQEEKMQE 569
Score = 36.6 bits (83), Expect = 0.037
Identities = 68/357 (19%), Positives = 138/357 (38%), Gaps = 53/357 (14%)
Query: 13 KAAPGLIDSFSEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKA 72
K A L + S + ++ + E+ L+ R A LE + R+ + +E +E K
Sbjct: 160 KFAGELEQALSAVATQKKKADRYIEE-LTKERDALSLE----LYRNTITDEELKEKNAK- 213
Query: 73 SEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQ 132
+++KL L E + +++ V+ EL RK +R K LL Q Q L K+
Sbjct: 214 --------LQEKLQLVESEKSEIQLNVK----ELKRKLERAKLLLPQQQLQAEADHLGKE 261
Query: 133 YQGKLQKMKAL---------------EETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQ 177
Q K++A E+ R +EK+ E+ E++ E + R + + RQ
Sbjct: 262 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ 321
Query: 178 QGKPYTGFPMLSASGLPL-----------GSMGENLPVELYSVLLAENAKLRTELDKNRH 226
+ + + + M E + E K+R E +K +
Sbjct: 322 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR-EQEKRQE 380
Query: 227 QQAPIILQQQALPVDPGELGAGGDLTERLQETHGPGHSEC----TETLPAQDLLSGTSDK 282
Q+A + Q++ + ++ ++ + +E G + E ++ + +K
Sbjct: 381 QEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEK 440
Query: 283 F-NLLAKLEHAQSRILSLESQLEDSARRWGREKQDLA---TRLQEQEKGFRHPSNSI 335
K+ + +I E +++ + G ++ + ++QEQE+ R I
Sbjct: 441 IREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKI 497
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 44.3 bits (103), Expect = 2e-04
Identities = 79/325 (24%), Positives = 137/325 (42%), Gaps = 28/325 (8%)
Query: 24 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQ 83
E+ RR Q+ E + R+ L E+ L +L E E G+ + EA K+
Sbjct: 849 ELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAERE-GRTLSEEATRLRLEKE 907
Query: 84 KLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKAL 143
L S ++++ +++ + +L + + LLL + + A L+Q Q+ +L
Sbjct: 908 ALEGSLFEVQRQLAQLEARREQLEAEG---QALLLAKETLTGELAGLRQQIIATQEKASL 964
Query: 144 EETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLP 203
++ + Q+ V + E R Q + L R Q + + L A L S +
Sbjct: 965 DKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQ 1024
Query: 204 VELYSVLLAENAKLRTELDKNRHQQAPIIL-----QQQALPVDPGELGAGGDLTERLQET 258
EL + L AE +L E+ + ++ +L +QQAL + E A L+E+L
Sbjct: 1025 EELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTA---LSEKLM-- 1079
Query: 259 HGPGHSECTETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLA 318
G HS T +L + K + ++ E +S + +L S+L D R RE+ A
Sbjct: 1080 -GTRHSLATISLEME------RQKRDAQSRQEQDRSTVNALTSELRD--LRAQREEAAAA 1130
Query: 319 -----TRLQEQEKGFRHPSNSIIIE 338
RLQEQ + +S + E
Sbjct: 1131 HAQEVRRLQEQARDLGKQRDSCLRE 1155
Score = 40.4 bits (93), Expect = 0.003
Identities = 32/126 (25%), Positives = 62/126 (49%), Gaps = 8/126 (6%)
Query: 25 MNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQN---TVSM 81
+ R+ + ++ LRRQ +L+ EN L LA+ + G+ +E ++ T+ +
Sbjct: 1268 LQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGL 1327
Query: 82 KQKLLLSELDMKKLRDRVQHLQNELIRK----NDREKELL-LLYQAQQPQAALLKQYQGK 136
+Q+LL E ++ +R +Q Q +L + RE+ LL L +A+ + L +G
Sbjct: 1328 RQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGL 1387
Query: 137 LQKMKA 142
K++A
Sbjct: 1388 ELKLEA 1393
Score = 36.6 bits (83), Expect = 0.037
Identities = 80/368 (21%), Positives = 143/368 (38%), Gaps = 57/368 (15%)
Query: 18 LIDSFSEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEE----------- 66
L DS S+++ + +A+D L L R + LE E L+ R Q E+E
Sbjct: 734 LQDSLSKLSALN---ESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERL 790
Query: 67 --------------EGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELI----- 107
EG + +E Q +++Q+L + +L++++ L +L
Sbjct: 791 EELRLEQEVARQGLEGSLRVAE-QAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQE 849
Query: 108 ---RKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDR 164
+ + ++++ L +A + + AL K++ G ++ A E R + E+ R+ ++
Sbjct: 850 LEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAE---REGRTLSEEATRLRLEK 906
Query: 165 LQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSV---LLAENAKLRTEL 221
+ RQ + L A G L E L EL + ++A K L
Sbjct: 907 EALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEK--ASL 964
Query: 222 DKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQETHGPGHSEC-TETLPAQDLLSGTS 280
DK Q + +++A + A + +RLQ E E Q L
Sbjct: 965 DKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQ 1024
Query: 281 DKF--NLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQEK--------GFRH 330
++ L A+ E I +L+ + ++ EKQ A L+E EK G RH
Sbjct: 1025 EELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQ-ALSLKESEKTALSEKLMGTRH 1083
Query: 331 PSNSIIIE 338
+I +E
Sbjct: 1084 SLATISLE 1091
Score = 35.0 bits (79), Expect = 0.11
Identities = 28/144 (19%), Positives = 65/144 (45%), Gaps = 3/144 (2%)
Query: 25 MNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVS---M 81
+ + +RA+ ++ + + R A LE + LR L + E E+ + + + +
Sbjct: 1847 LGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRL 1906
Query: 82 KQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMK 141
+ L +EL++ + + ++Q L+ +++ L AQQ Q L ++ +
Sbjct: 1907 DRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQA 1966
Query: 142 ALEETVRHQEKVIEKMERVLEDRL 165
E T+ +E+ + R LE+++
Sbjct: 1967 QTERTLEARERAHRQRVRGLEEQV 1990
>gi|16554562 caspase recruitment domain protein 9 isoform 2 [Homo
sapiens]
Length = 492
Score = 44.3 bits (103), Expect = 2e-04
Identities = 76/345 (22%), Positives = 142/345 (41%), Gaps = 37/345 (10%)
Query: 23 SEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQG--KASEAQNTV- 79
S + ++ +Q++ E+ + R+ + EN L RLA Q EE+G + + Q +
Sbjct: 152 SLLRKHQERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEID 211
Query: 80 SMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQK 139
+K L+ +E D K R L++ + ++ +E LL++ QQ +A L Q ++Q+
Sbjct: 212 QLKHSLMKAEDDCKVERKHTLKLRHAMEQRPSQE----LLWELQQEKALL----QARVQE 263
Query: 140 MKA--LEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGS 197
++A E + I+ +E L+D + K + L
Sbjct: 264 LEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANTIFSLRK-----DLRQGEARRLRC 318
Query: 198 MGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQE 257
M E EL + L +++K+ K+R + I+LQ + + ++ + A E L
Sbjct: 319 MEEKEMFELQCLALRKDSKMY----KDRIE--AILLQMEEVAIERDQAIA---TREELHA 369
Query: 258 THGPGHSECTETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDL 317
H G L +D L L K + Q ++ E+QL R R++ +
Sbjct: 370 QHARG-------LQEKDAL--RKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLET 420
Query: 318 ATRLQEQEKGFRHPSNSIIIEQPVSDPPGVAPRGSGGGAGSHRTP 362
+ E G S + + Q + D ++ +G G GS + P
Sbjct: 421 LVLSSDLEDGSPRRSQELSLPQDLEDTQ-LSDKGCLAGGGSPKQP 464
>gi|47717131 caspase recruitment domain protein 9 isoform 1 [Homo
sapiens]
Length = 536
Score = 44.3 bits (103), Expect = 2e-04
Identities = 76/345 (22%), Positives = 142/345 (41%), Gaps = 37/345 (10%)
Query: 23 SEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQG--KASEAQNTV- 79
S + ++ +Q++ E+ + R+ + EN L RLA Q EE+G + + Q +
Sbjct: 152 SLLRKHQERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEID 211
Query: 80 SMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQK 139
+K L+ +E D K R L++ + ++ +E LL++ QQ +A L Q ++Q+
Sbjct: 212 QLKHSLMKAEDDCKVERKHTLKLRHAMEQRPSQE----LLWELQQEKALL----QARVQE 263
Query: 140 MKA--LEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGS 197
++A E + I+ +E L+D + K + L
Sbjct: 264 LEASVQEGKLDRSSPYIQVLEEDWRQALRDHQEQANTIFSLRK-----DLRQGEARRLRC 318
Query: 198 MGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQE 257
M E EL + L +++K+ K+R + I+LQ + + ++ + A E L
Sbjct: 319 MEEKEMFELQCLALRKDSKMY----KDRIE--AILLQMEEVAIERDQAIA---TREELHA 369
Query: 258 THGPGHSECTETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDL 317
H G L +D L L K + Q ++ E+QL R R++ +
Sbjct: 370 QHARG-------LQEKDAL--RKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLET 420
Query: 318 ATRLQEQEKGFRHPSNSIIIEQPVSDPPGVAPRGSGGGAGSHRTP 362
+ E G S + + Q + D ++ +G G GS + P
Sbjct: 421 LVLSSDLEDGSPRRSQELSLPQDLEDTQ-LSDKGCLAGGGSPKQP 464
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 43.9 bits (102), Expect = 2e-04
Identities = 59/299 (19%), Positives = 126/299 (42%), Gaps = 33/299 (11%)
Query: 29 RRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLS 88
R +KM LR Q L + + LR + +E+EE + E K+
Sbjct: 310 REQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEE---------KMWEQ 360
Query: 89 ELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVR 148
E +K+R++ + + + R ++EK++ Q + Q + + ++++ EE +R
Sbjct: 361 E---EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD---ERLREKEERMR 414
Query: 149 HQEKVIEKMERVLED-RLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELY 207
QEK+ E++E++ E+ ++Q++ K R Q + + + E
Sbjct: 415 EQEKMWEQVEKMREEKKMQEQEKK---TRDQEEKMQEEERIREREKKMREEEET------ 465
Query: 208 SVLLAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQETHGPGHSECT 267
+ E + + ++N +Q QQQ LP +L + E+ ++ E
Sbjct: 466 ---MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW-----EQE 517
Query: 268 ETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQEK 326
E + Q+ + G K K+ + ++ E ++ D ++ +++ + + QEQEK
Sbjct: 518 EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEK 576
Score = 42.0 bits (97), Expect = 9e-04
Identities = 36/153 (23%), Positives = 73/153 (47%), Gaps = 13/153 (8%)
Query: 38 DILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQ-NTVSMKQKL-----LLSELD 91
D LSL + + E ++ Q++ + + SE Q N +K+KL LL ++
Sbjct: 207 DALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQ 266
Query: 92 MKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKL----QKMKALEETV 147
L++ + + EL ++EK++ + Q L++ +GK+ +KM E+ +
Sbjct: 267 TNTLQEEMWRQEEEL---REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRL 323
Query: 148 RHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGK 180
R QEK + + E+ L ++ + R + + Q+ K
Sbjct: 324 REQEKELREQEKELREQKELREQEEQMQEQEEK 356
Score = 36.6 bits (83), Expect = 0.037
Identities = 32/136 (23%), Positives = 68/136 (50%), Gaps = 8/136 (5%)
Query: 33 QKMAEDILSLRRQASILEGENRILRS--RLAQQEEEEGQGKASEAQNTVSMKQKLLLSEL 90
Q++ E L Q + E E +I ++ QEE GQ K Q + ++ + +
Sbjct: 491 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 550
Query: 91 DMKKLRDRVQHL--QNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVR 148
+ K+RD+ Q + Q E + K +E+E Q ++ + ++ + + +KM+ EE +R
Sbjct: 551 E--KMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREE--ERMREREKKMREEEEMMR 606
Query: 149 HQEKVIEKMERVLEDR 164
QE+ +++ E ++++
Sbjct: 607 EQEEKMQEQEEKMQEQ 622
Score = 33.9 bits (76), Expect = 0.24
Identities = 30/148 (20%), Positives = 72/148 (48%), Gaps = 8/148 (5%)
Query: 25 MNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEE--EGQGKASEAQNTVSMK 82
M MQ+ E + + E + + ++ +QEE+ E + K E Q K
Sbjct: 605 MREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQK 664
Query: 83 QKLLLSEL--DMKKLRDRVQHL-QNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQK 139
+KL E + +K++++ + + + E + K +E+E Q + + +++ + +K
Sbjct: 665 EKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE---KK 721
Query: 140 MKALEETVRHQEKVIEKMERVLEDRLQD 167
M+ EE +R QE+ +++ E ++++ ++
Sbjct: 722 MREEEEMMREQEEKMQEQEEKMQEQEEE 749
Score = 33.9 bits (76), Expect = 0.24
Identities = 26/132 (19%), Positives = 62/132 (46%), Gaps = 3/132 (2%)
Query: 24 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEG---QGKASEAQNTVS 80
+M + +K D +R + S+ E E ++ +E+EE Q + + Q
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEM 750
Query: 81 MKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKM 140
+Q+ + E + K + Q E + ++++ +E +++ ++ ++ +G+ +KM
Sbjct: 751 WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKM 810
Query: 141 KALEETVRHQEK 152
+ EE +R QE+
Sbjct: 811 RGQEEKMRGQEE 822
Score = 32.7 bits (73), Expect = 0.53
Identities = 34/156 (21%), Positives = 72/156 (46%), Gaps = 14/156 (8%)
Query: 24 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEE---EGQGKASEAQNTV- 79
E R +KM E + +R + + E E + QEEE E + K E + T+
Sbjct: 408 EKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMR 467
Query: 80 SMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKL-- 137
++K+ E +M + ++ Q + +KE L + Q Q + + + K+
Sbjct: 468 EQEEKMQKQEENMWEQEEKEWQQQ-----RLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 522
Query: 138 -QKMKALEETVRHQEKVIEKMERV--LEDRLQDRSK 170
++M E+ + QEK+ E+ +++ E++++D+ +
Sbjct: 523 QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ 558
Score = 31.6 bits (70), Expect = 1.2
Identities = 31/158 (19%), Positives = 77/158 (48%), Gaps = 10/158 (6%)
Query: 20 DSFSEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSR---LAQQEEE--EGQGKASE 74
+ E + R +KM E+ +R Q ++ + ++ + + +QEE+ E + K E
Sbjct: 707 EKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWE 766
Query: 75 AQNTVSMKQKLLLSEL--DMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQ 132
Q K+KL E + +K+ ++ + ++++ + +E+++ + + Q ++
Sbjct: 767 QQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE---EK 823
Query: 133 YQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSK 170
G+ +KM EE + QE+ + E +E+++Q + +
Sbjct: 824 MWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEE 861
Score = 28.5 bits (62), Expect = 10.0
Identities = 28/124 (22%), Positives = 59/124 (47%), Gaps = 14/124 (11%)
Query: 44 RQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQ 103
RQ + E E+++ +++E+ E + +Q+ KK D+ + ++
Sbjct: 535 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQE--------KKTWDQEEKMR 586
Query: 104 NELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQ----KMKALEETVRHQE-KVIEKME 158
E R +REK++ + + Q +++ + K+Q KM EE ++ QE K+ E+ E
Sbjct: 587 EEE-RMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE 645
Query: 159 RVLE 162
++ E
Sbjct: 646 KMWE 649
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 43.5 bits (101), Expect = 3e-04
Identities = 83/338 (24%), Positives = 131/338 (38%), Gaps = 72/338 (21%)
Query: 11 APKAAPGLIDSFSEMNNYRRAMQKMAEDILSLRRQASILEGENRI--------------L 56
A +A G+++ ++ R A++ E++ S R +A L+ + + L
Sbjct: 1369 AQASAAGILEE--DLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALL 1426
Query: 57 RSRLAQQEEE----EGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDR 112
LA++EEE GQ + E Q + K L L LD+KK V LQ E I++ ++
Sbjct: 1427 TQTLAEREEEVETLRGQIQELEKQREMQ-KAALELLSLDLKKRNQEVD-LQQEQIQELEK 1484
Query: 113 EKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPP 172
+ +L P A Q + QK+ E +R EK E VLE +L + K
Sbjct: 1485 CRSVL----EHLPMAV-----QEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKD 1535
Query: 173 PLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAEN-------AKLRTELDKNR 225
+ Q G + + +E ++ L EN KL EL+ R
Sbjct: 1536 QMIESQ------------RGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQR 1583
Query: 226 HQQAPIILQQQALPVDPGELGAGGDLTERLQETHGPGHSECTETLPAQDLLSGTSDKFNL 285
Q + L L DL ER QE ++ DL S ++ L
Sbjct: 1584 ETQR-VALTHLTL-----------DLEERSQELQ-------AQSSQIHDLESHST---VL 1621
Query: 286 LAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQE 323
+L+ + S Q+E+ R+ QDL R QE
Sbjct: 1622 ARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQE 1659
Score = 36.2 bits (82), Expect = 0.048
Identities = 66/317 (20%), Positives = 140/317 (44%), Gaps = 41/317 (12%)
Query: 25 MNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQK 84
+ + R +Q + + +++L A LE + + + +E EGQ + Q+
Sbjct: 1538 IESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRET----------QR 1587
Query: 85 LLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALE 144
+ L+ L + L +R Q LQ + + +D E +L + Q + +K + ++++++ +
Sbjct: 1588 VALTHLTLD-LEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQK 1646
Query: 145 ETV------RHQEKVIEKME-RVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGS 197
E + R QE +++K +VLED+ ++K + +Q K L L
Sbjct: 1647 EHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIK------------LSLRE 1694
Query: 198 MGENLPVELYSVL-LAENAKLRTELDKNRHQQAPIILQQQALPVDPGE--LGAGGDLTER 254
G L + + AE K ++ + + +IL+ + V+ + + +L ++
Sbjct: 1695 RGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQ 1754
Query: 255 LQETHGPGHSECTETLPAQDLLSGTSDKFNLLAKL-----EHAQSRILSLESQLEDSARR 309
L++ H + ET LLS + +L + E + + SL+SQL+++ R
Sbjct: 1755 LEQQLQGLHRKVGET---SLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRA 1811
Query: 310 WGREKQDLATRLQEQEK 326
+ Q+L QEQ++
Sbjct: 1812 LAQRDQELEALQQEQQQ 1828
Score = 34.3 bits (77), Expect = 0.18
Identities = 64/308 (20%), Positives = 128/308 (41%), Gaps = 20/308 (6%)
Query: 29 RRAMQKMAEDILSLRRQASILEGENRIL---RSRLAQQEEEEGQGKASEAQNTVSMKQKL 85
R+ +QK+ + +L Q L+GE L R L + EE Q Q +++
Sbjct: 434 RQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVN 493
Query: 86 LLSELDMKKLRDRVQHLQNEL---IRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKA 142
+ +L + + + Q EL +R+ +R +E+L+ +A+Q ++ + +A
Sbjct: 494 VELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESL-----SELITLREA 548
Query: 143 LEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENL 202
LE + E + ++ V + L+ + T L A+ + L ++ E L
Sbjct: 549 LESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEAL 608
Query: 203 PVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQE--THG 260
++ + N +L ++N+ + + +QA +L E L E TH
Sbjct: 609 ALDKVGL----NQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHL 664
Query: 261 PGHSECTETLPAQ---DLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDL 317
+ E A+ DL +K + KL ++ + + +QLE + R+++ L
Sbjct: 665 EAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVL 724
Query: 318 ATRLQEQE 325
A +QE+E
Sbjct: 725 ARAVQEKE 732
Score = 33.1 bits (74), Expect = 0.41
Identities = 71/341 (20%), Positives = 130/341 (38%), Gaps = 79/341 (23%)
Query: 23 SEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMK 82
S+++ +RA+ + +++ +L+++ +G+ ++ ++ + QG +A T+ +
Sbjct: 1803 SQLDEAQRALAQRDQELEALQQEQQQAQGQEERVK-----EKADALQGALEQAHMTLKER 1857
Query: 83 QKLLLSELDMKKLRD--------RVQHLQNEL--IRKNDREKELLLLY-------QAQQP 125
L + + + RVQ L+ L +R RE+E LL QAQ+
Sbjct: 1858 HGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEH 1917
Query: 126 QA-------------ALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPP 172
+ A+LK+ +L+ ++A ++ RHQE+ L++ L
Sbjct: 1918 EVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEAL------- 1970
Query: 173 PLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPII 232
GK + L EL L A A L+ LD + +
Sbjct: 1971 ------GKAHAALQGKEQHLLE--------QAELSRSLEASTATLQASLDACQAHSRQL- 2015
Query: 233 LQQQALPVDPGELGAGGDLTERLQETHGPGHSECTETLPAQDLLSGTSDKFNLLAKLEHA 292
++AL + GE+ D R QE + + L +D +L H
Sbjct: 2016 --EEALRIQEGEI---QDQDLRYQE----DVQQLQQALAQRD------------EELRHQ 2054
Query: 293 QSRILSLESQLEDSAR-RWGREKQDLATRLQEQEKGFRHPS 332
Q R LE L + +EKQ+L +E+E H S
Sbjct: 2055 QEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQS 2095
Score = 32.7 bits (73), Expect = 0.53
Identities = 62/302 (20%), Positives = 126/302 (41%), Gaps = 17/302 (5%)
Query: 32 MQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELD 91
+++ +++ +LR ++ + R+R +E G+ A+ + K++ LL + +
Sbjct: 1935 LKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAA-----LQGKEQHLLEQAE 1989
Query: 92 MKK-LRDRVQHLQNEL--IRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKAL---EE 145
+ + L LQ L + + R+ E L Q + Q L+ + Q +AL +E
Sbjct: 1990 LSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDE 2049
Query: 146 TVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVE 205
+RHQ++ + +E+ L R+Q+ N Q + L S + + L +
Sbjct: 2050 ELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQS---VRELQLTLAQK 2106
Query: 206 LYSVLLAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQETHGPGHS- 264
+L + R L+ H +++Q+L +D E +L ERLQ +
Sbjct: 2107 EQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQREL-ERLQAALRQTEAR 2165
Query: 265 ECTETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQ 324
E AQDL + ++ L+ + L DS ++ +++ +L R E+
Sbjct: 2166 EIEWREKAQDLALSLAQTKASVSSLQEV-AMFLQASVLERDSEQQRLQDELELTRRALEK 2224
Query: 325 EK 326
E+
Sbjct: 2225 ER 2226
Score = 32.0 bits (71), Expect = 0.90
Identities = 34/162 (20%), Positives = 74/162 (45%), Gaps = 17/162 (10%)
Query: 29 RRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLS 88
R +QK+ E + + S + E + L+ +L+Q +EE+ + + + S++ +L+
Sbjct: 1263 RDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQN----SLESELMEL 1318
Query: 89 ELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKA------ 142
M L+ R++ + +++ + + E LL A++ A ++ Q + + +A
Sbjct: 1319 HETMASLQSRLRRAE---LQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAG 1375
Query: 143 -LEETVRHQEKVIEKMERVLE---DRLQDRSKPPPLNRQQGK 180
LEE +R ++ +E +R Q + L QGK
Sbjct: 1376 ILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGK 1417
Score = 28.9 bits (63), Expect = 7.6
Identities = 44/188 (23%), Positives = 86/188 (45%), Gaps = 25/188 (13%)
Query: 20 DSFSEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTV 79
+ E Y R +++ + SL S++E E R+L + Q+ + Q + S
Sbjct: 1035 EKLRETQEYNRIQKELEREKASLT--LSLMEKEQRLL---VLQEADSIRQQELS------ 1083
Query: 80 SMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQK 139
+++Q + ++ + K+L Q EL+R+ +EKE L Q +A LL++ +
Sbjct: 1084 ALRQDMQEAQGEQKELS-----AQMELLRQEVKEKEADFLAQ----EAQLLEELEASHIT 1134
Query: 140 MKALEETVRHQEKVIEKME---RVLEDRLQD-RSKPPPLNRQQGKPYTGFPMLSASGLPL 195
+ L ++ QE +++ R E +L+ ++ P N+ Q + + SA L
Sbjct: 1135 EQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLA-SLYSALQQAL 1193
Query: 196 GSMGENLP 203
GS+ E+ P
Sbjct: 1194 GSVCESRP 1201
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 43.1 bits (100), Expect = 4e-04
Identities = 31/154 (20%), Positives = 79/154 (51%), Gaps = 9/154 (5%)
Query: 30 RAMQKMAEDILSLRRQASILEGENRILRS---RLAQQEEEEGQGKASEAQNTVSMKQKLL 86
R +K+ E +R Q + + +R ++ +QEEE + + + ++K+
Sbjct: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409
Query: 87 LSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEET 146
E M++ ++++ + E+ R+ ++ +EL + Q Q+ + L++ + K+Q+ EE
Sbjct: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEK---LREVEEKMQEE---EEK 463
Query: 147 VRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGK 180
++ QE+ I++ E ++++ + + L +Q+ K
Sbjct: 464 MQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK 497
Score = 37.4 bits (85), Expect = 0.021
Identities = 63/304 (20%), Positives = 124/304 (40%), Gaps = 28/304 (9%)
Query: 40 LSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTV-SMKQKLLLSELDMKKLRDR 98
L+ R A LE + R+ + +E +E + E V S K ++ L+ D+K+ +R
Sbjct: 195 LTKERDAPSLE----LYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
Query: 99 VQHL--QNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEK 156
Q L Q +L + DR + L A+ QA + + L + E+ R +EK+ E+
Sbjct: 251 AQLLLPQQQLQVEADRLGKELQSVSAKL-QAQVEENELWNLLNQQQEEKMWRQEEKIQEQ 309
Query: 157 MERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAK 216
E++ E L+ R + + RQ+ K + E E + + K
Sbjct: 310 EEKMCEQELKIREQEEKMWRQEEKMHE---------------QEEKIREQEDKMWRQEEK 354
Query: 217 LRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQETHGPGHSECTETLPAQDLL 276
+R + +K R Q+ + Q++ + ++ + R +E + E + Q+
Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKK 414
Query: 277 SGTSDK--FNLLAKLEHAQSRILSLESQLED---SARRWGREKQDLATRLQEQEKGFRHP 331
D+ ++ + +I LE ++D R + Q+ ++QEQE+ +
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Query: 332 SNSI 335
I
Sbjct: 475 EEKI 478
Score = 31.6 bits (70), Expect = 1.2
Identities = 47/218 (21%), Positives = 95/218 (43%), Gaps = 16/218 (7%)
Query: 30 RAMQKMAEDILSLRRQASIL-EGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLS 88
R +KM E +R Q + E +I Q++EE + E ++K+
Sbjct: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ--EEEEKMQEQ 467
Query: 89 ELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVR 148
E +++ +++Q + + R+ K+ +++ ++ ++ + +KM+ EE ++
Sbjct: 468 EEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQ 527
Query: 149 HQEKVIEKMERVL---EDRLQDRS-KPPPLNRQQGKPYTGFPMLSASGLPLGS-----MG 199
QE+ + + E L E+++Q++ + L + GK +L +G GS +
Sbjct: 528 RQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLT 587
Query: 200 ENLPVELYSVLLAENAKLRTELDKNR-HQQAPIILQQQ 236
L VEL S E L+ + D R H Q + QQ
Sbjct: 588 PILQVELKS---QEAQSLQQQQDHYRGHLQQYVAAYQQ 622
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 43.1 bits (100), Expect = 4e-04
Identities = 31/154 (20%), Positives = 79/154 (51%), Gaps = 9/154 (5%)
Query: 30 RAMQKMAEDILSLRRQASILEGENRILRS---RLAQQEEEEGQGKASEAQNTVSMKQKLL 86
R +K+ E +R Q + + +R ++ +QEEE + + + ++K+
Sbjct: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409
Query: 87 LSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEET 146
E M++ ++++ + E+ R+ ++ +EL + Q Q+ + L++ + K+Q+ EE
Sbjct: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEK---LREVEEKMQEE---EEK 463
Query: 147 VRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGK 180
++ QE+ I++ E ++++ + + L +Q+ K
Sbjct: 464 MQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK 497
Score = 37.0 bits (84), Expect = 0.028
Identities = 63/304 (20%), Positives = 124/304 (40%), Gaps = 28/304 (9%)
Query: 40 LSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTV-SMKQKLLLSELDMKKLRDR 98
L+ R A LE + R+ + +E +E + E V S K ++ L+ D+K+ +R
Sbjct: 195 LTKERDALSLE----LYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
Query: 99 VQHL--QNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEK 156
Q L Q +L + DR + L A+ QA + + L + E+ R +EK+ E+
Sbjct: 251 AQLLLPQQQLQVEADRLGKELQSVSAKL-QAQVEENELWNLLNQQQEEKMWRQEEKIQEQ 309
Query: 157 MERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAK 216
E++ E L+ R + + RQ+ K + E E + + K
Sbjct: 310 EEKMCEQELKIREQEEKMWRQEEKMHE---------------QEEKIREQEDKMWRQEEK 354
Query: 217 LRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQETHGPGHSECTETLPAQDLL 276
+R + +K R Q+ + Q++ + ++ + R +E + E + Q+
Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKK 414
Query: 277 SGTSDK--FNLLAKLEHAQSRILSLESQLED---SARRWGREKQDLATRLQEQEKGFRHP 331
D+ ++ + +I LE ++D R + Q+ ++QEQE+ +
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Query: 332 SNSI 335
I
Sbjct: 475 EEKI 478
Score = 31.6 bits (70), Expect = 1.2
Identities = 47/218 (21%), Positives = 95/218 (43%), Gaps = 16/218 (7%)
Query: 30 RAMQKMAEDILSLRRQASIL-EGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLS 88
R +KM E +R Q + E +I Q++EE + E ++K+
Sbjct: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ--EEEEKMQEQ 467
Query: 89 ELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVR 148
E +++ +++Q + + R+ K+ +++ ++ ++ + +KM+ EE ++
Sbjct: 468 EEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQ 527
Query: 149 HQEKVIEKMERVL---EDRLQDRS-KPPPLNRQQGKPYTGFPMLSASGLPLGS-----MG 199
QE+ + + E L E+++Q++ + L + GK +L +G GS +
Sbjct: 528 RQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLT 587
Query: 200 ENLPVELYSVLLAENAKLRTELDKNR-HQQAPIILQQQ 236
L VEL S E L+ + D R H Q + QQ
Sbjct: 588 PILQVELKS---QEAQSLQQQQDHYRGHLQQYVAAYQQ 622
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 42.7 bits (99), Expect = 5e-04
Identities = 70/325 (21%), Positives = 137/325 (42%), Gaps = 47/325 (14%)
Query: 33 QKMAEDILSLRRQASILE---GENRILRSRLAQQEEE---EGQGKASEAQNTVSMKQKLL 86
QK E +L+++ S+L+ GE R R A++ EE + + +A++++ V ++L
Sbjct: 2060 QKEQELQQTLQQEQSVLDQLRGEAEAAR-RAAEEAEEARVQAEREAAQSRRQVEEAERLK 2118
Query: 87 LSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEET 146
S + + R + Q +L + + E+E QA+Q + +++K K E
Sbjct: 2119 QSAEEQAQARAQAQAAAEKL--RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2176
Query: 147 VRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVEL 206
Q+ +E+ L +L++ L ++ L A + EL
Sbjct: 2177 TLRQKAQVEQELTTLRLQLEETDHQKNLLDEE------LQRLKAEATEAARQRSQVEEEL 2230
Query: 207 YSVL--LAENAKLRTEL----------DKNRHQQAPIILQQQA-----LPVDPGELGAGG 249
+SV + E +KL+ + DK+ Q+ LQ++A + + L
Sbjct: 2231 FSVRVQMEELSKLKARIEAENRALILRDKDNTQR---FLQEEAEKMKQVAEEAARLSVAA 2287
Query: 250 DLTERLQETHGPGHSECTETLPAQDLLSGTSDKFNLLAKLE----HAQSRILSLESQL-E 304
RL++ E L Q L+ K + A E A++ +L + +L +
Sbjct: 2288 QEAARLRQL-------AEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ 2340
Query: 305 DSARRWGREKQDLATRLQEQEKGFR 329
+ ARR +K+ +A +L E+ +GF+
Sbjct: 2341 EQARRLQEDKEQMAQQLAEETQGFQ 2365
Score = 35.8 bits (81), Expect = 0.062
Identities = 52/278 (18%), Positives = 118/278 (42%), Gaps = 26/278 (9%)
Query: 33 QKMAEDILSLRRQASILEGENRILRSRLAQ----QEEEEGQGKASEAQNTVSMKQKLLLS 88
+++ E I L R+ L+ E ++L+ + + Q+E+ Q + Q+ +S K LL
Sbjct: 2446 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2505
Query: 89 ELDMKKLRDRVQHLQNELIRK----------------NDREKELLLLYQAQQPQAALLKQ 132
E +++ + +++ L + + K +R++ + + +A++ Q +
Sbjct: 2506 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2565
Query: 133 YQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASG 192
+ K ++++ LE+ R QE+++ + + L ++LQ + + T + +
Sbjct: 2566 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKT 2625
Query: 193 LPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLT 252
LP G + P + + LR ++ R Q+A I+ ++ L G
Sbjct: 2626 LPNGRDALDGPAAEAEPEHSFDG-LRRKVSAQRLQEAGILSAEEL-----QRLAQGHTTV 2679
Query: 253 ERLQETHGPGHSECTETLPAQDLLSGTSDKFNLLAKLE 290
+ L H + A LL T++K ++ A L+
Sbjct: 2680 DELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQ 2717
Score = 28.9 bits (63), Expect = 7.6
Identities = 63/309 (20%), Positives = 125/309 (40%), Gaps = 47/309 (15%)
Query: 44 RQASILEGENRILRSRLAQ------QEEEEGQGKASEAQNTVSMKQKL-------LLSEL 90
RQ EGE + LR+R + Q +EE + + Q+ K++ + +E
Sbjct: 1466 RQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEA 1525
Query: 91 DMKKLRDR-VQHLQNELIRKNDREKEL--LLLYQAQQPQAAL---LKQYQGKLQKMKA-- 142
+ + + R +Q L+ ++ + E+ L + +A+Q Q AL + + +LQ +A
Sbjct: 1526 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASF 1585
Query: 143 ------LEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLG 196
LE +++ + + ++ E R Q +++ + + + + + L L
Sbjct: 1586 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1645
Query: 197 SMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQ 256
E + + S+ AE K + E ++ ++ ++QA V EL A +L ++ Q
Sbjct: 1646 LQAEEV-AQQKSLAQAEAEKQKEEAEREARRRGK--AEEQA--VRQREL-AEQELEKQRQ 1699
Query: 257 ETHGPGHSECTETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQD 316
G AQ L+ + L A+ E + + LE+ R RE
Sbjct: 1700 LAEG----------TAQQRLAAEQELIRLRAETEQGEQQ----RQLLEEELARLQREAAA 1745
Query: 317 LATRLQEQE 325
+ QE E
Sbjct: 1746 ATQKRQELE 1754
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 42.7 bits (99), Expect = 5e-04
Identities = 70/325 (21%), Positives = 137/325 (42%), Gaps = 47/325 (14%)
Query: 33 QKMAEDILSLRRQASILE---GENRILRSRLAQQEEE---EGQGKASEAQNTVSMKQKLL 86
QK E +L+++ S+L+ GE R R A++ EE + + +A++++ V ++L
Sbjct: 2064 QKEQELQQTLQQEQSVLDQLRGEAEAAR-RAAEEAEEARVQAEREAAQSRRQVEEAERLK 2122
Query: 87 LSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEET 146
S + + R + Q +L + + E+E QA+Q + +++K K E
Sbjct: 2123 QSAEEQAQARAQAQAAAEKL--RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2180
Query: 147 VRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVEL 206
Q+ +E+ L +L++ L ++ L A + EL
Sbjct: 2181 TLRQKAQVEQELTTLRLQLEETDHQKNLLDEE------LQRLKAEATEAARQRSQVEEEL 2234
Query: 207 YSVL--LAENAKLRTEL----------DKNRHQQAPIILQQQA-----LPVDPGELGAGG 249
+SV + E +KL+ + DK+ Q+ LQ++A + + L
Sbjct: 2235 FSVRVQMEELSKLKARIEAENRALILRDKDNTQR---FLQEEAEKMKQVAEEAARLSVAA 2291
Query: 250 DLTERLQETHGPGHSECTETLPAQDLLSGTSDKFNLLAKLE----HAQSRILSLESQL-E 304
RL++ E L Q L+ K + A E A++ +L + +L +
Sbjct: 2292 QEAARLRQL-------AEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ 2344
Query: 305 DSARRWGREKQDLATRLQEQEKGFR 329
+ ARR +K+ +A +L E+ +GF+
Sbjct: 2345 EQARRLQEDKEQMAQQLAEETQGFQ 2369
Score = 35.8 bits (81), Expect = 0.062
Identities = 52/278 (18%), Positives = 118/278 (42%), Gaps = 26/278 (9%)
Query: 33 QKMAEDILSLRRQASILEGENRILRSRLAQ----QEEEEGQGKASEAQNTVSMKQKLLLS 88
+++ E I L R+ L+ E ++L+ + + Q+E+ Q + Q+ +S K LL
Sbjct: 2450 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2509
Query: 89 ELDMKKLRDRVQHLQNELIRK----------------NDREKELLLLYQAQQPQAALLKQ 132
E +++ + +++ L + + K +R++ + + +A++ Q +
Sbjct: 2510 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2569
Query: 133 YQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASG 192
+ K ++++ LE+ R QE+++ + + L ++LQ + + T + +
Sbjct: 2570 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKT 2629
Query: 193 LPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLT 252
LP G + P + + LR ++ R Q+A I+ ++ L G
Sbjct: 2630 LPNGRDALDGPAAEAEPEHSFDG-LRRKVSAQRLQEAGILSAEEL-----QRLAQGHTTV 2683
Query: 253 ERLQETHGPGHSECTETLPAQDLLSGTSDKFNLLAKLE 290
+ L H + A LL T++K ++ A L+
Sbjct: 2684 DELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQ 2721
Score = 28.9 bits (63), Expect = 7.6
Identities = 63/309 (20%), Positives = 125/309 (40%), Gaps = 47/309 (15%)
Query: 44 RQASILEGENRILRSRLAQ------QEEEEGQGKASEAQNTVSMKQKL-------LLSEL 90
RQ EGE + LR+R + Q +EE + + Q+ K++ + +E
Sbjct: 1470 RQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEA 1529
Query: 91 DMKKLRDR-VQHLQNELIRKNDREKEL--LLLYQAQQPQAAL---LKQYQGKLQKMKA-- 142
+ + + R +Q L+ ++ + E+ L + +A+Q Q AL + + +LQ +A
Sbjct: 1530 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASF 1589
Query: 143 ------LEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLG 196
LE +++ + + ++ E R Q +++ + + + + + L L
Sbjct: 1590 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1649
Query: 197 SMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQ 256
E + + S+ AE K + E ++ ++ ++QA V EL A +L ++ Q
Sbjct: 1650 LQAEEV-AQQKSLAQAEAEKQKEEAEREARRRGK--AEEQA--VRQREL-AEQELEKQRQ 1703
Query: 257 ETHGPGHSECTETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQD 316
G AQ L+ + L A+ E + + LE+ R RE
Sbjct: 1704 LAEG----------TAQQRLAAEQELIRLRAETEQGEQQ----RQLLEEELARLQREAAA 1749
Query: 317 LATRLQEQE 325
+ QE E
Sbjct: 1750 ATQKRQELE 1758
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,119,030
Number of Sequences: 37866
Number of extensions: 813360
Number of successful extensions: 9201
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 154
Number of HSP's successfully gapped in prelim test: 571
Number of HSP's that attempted gapping in prelim test: 6433
Number of HSP's gapped (non-prelim): 3121
length of query: 367
length of database: 18,247,518
effective HSP length: 104
effective length of query: 263
effective length of database: 14,309,454
effective search space: 3763386402
effective search space used: 3763386402
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.