Search of human proteins with 239746595

Search of human proteins with 239746595

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239746595 PREDICTED: hypothetical protein XP_002343793 [Homo
sapiens]
         (663 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239746595 PREDICTED: hypothetical protein XP_002343793 [Homo ...  1405   0.0  
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]      42   0.002
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       40   0.009
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       40   0.009
gi|32479521 dishevelled 1 [Homo sapiens]                               39   0.020
gi|57864582 hornerin [Homo sapiens]                                    38   0.034
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]               37   0.058
gi|163965366 nascent polypeptide-associated complex alpha subuni...    37   0.076
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             36   0.099
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          36   0.099
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          36   0.099
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          36   0.099
gi|239757861 PREDICTED: similar to armadillo repeat containing, ...    36   0.13 
gi|239754873 PREDICTED: similar to hCG2040393 [Homo sapiens]           36   0.13 
gi|239749412 PREDICTED: hypothetical protein XP_002347031 [Homo ...    36   0.13 
gi|239743547 PREDICTED: hypothetical protein XP_002342883 [Homo ...    36   0.13 
gi|38373682 pleckstrin homology domain containing family G membe...    36   0.13 
gi|111154084 pleckstrin homology domain containing family G memb...    36   0.13 
gi|111154088 pleckstrin homology domain containing family G memb...    36   0.13 
gi|111154080 pleckstrin homology domain containing family G memb...    36   0.13 
gi|111154078 pleckstrin homology domain containing family G memb...    36   0.13 
gi|239753475 PREDICTED: hypothetical protein [Homo sapiens]            35   0.17 
gi|239748044 PREDICTED: hypothetical protein XP_002346500 [Homo ...    35   0.17 
gi|239741935 PREDICTED: hypothetical protein XP_002342357 [Homo ...    35   0.17 
gi|38016904 thrombospondin repeat containing 1 isoform 1 [Homo s...    35   0.17 
gi|56788359 thrombospondin repeat containing 1 isoform 2 [Homo s...    35   0.17 
gi|30039694 zinc finger protein 598 [Homo sapiens]                     35   0.17 
gi|62122917 filaggrin family member 2 [Homo sapiens]                   35   0.22 
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       35   0.22 
gi|4506321 protein tyrosine phosphatase, receptor type, N precur...    35   0.22 

>gi|239746595 PREDICTED: hypothetical protein XP_002343793 [Homo
           sapiens]
          Length = 663

 Score = 1405 bits (3636), Expect = 0.0
 Identities = 663/663 (100%), Positives = 663/663 (100%)

Query: 1   MSHNNALLAWCPPTLSSWCPPNTLLLGLMLSPMKIQDVSSAAPSICQQVQVLRTPPPLQA 60
           MSHNNALLAWCPPTLSSWCPPNTLLLGLMLSPMKIQDVSSAAPSICQQVQVLRTPPPLQA
Sbjct: 1   MSHNNALLAWCPPTLSSWCPPNTLLLGLMLSPMKIQDVSSAAPSICQQVQVLRTPPPLQA 60

Query: 61  PEGAAWLLTNPPQQHPQRPLSTQPSHGPYWPSPTHLISVGSAQSQGTITPSARHKGRWAP 120
           PEGAAWLLTNPPQQHPQRPLSTQPSHGPYWPSPTHLISVGSAQSQGTITPSARHKGRWAP
Sbjct: 61  PEGAAWLLTNPPQQHPQRPLSTQPSHGPYWPSPTHLISVGSAQSQGTITPSARHKGRWAP 120

Query: 121 DRGPPHTVDARAGLLQHGLVHLLGIEGRIPHAQLGTRGDVSGGGEVHVAAVLVGRQVLVL 180
           DRGPPHTVDARAGLLQHGLVHLLGIEGRIPHAQLGTRGDVSGGGEVHVAAVLVGRQVLVL
Sbjct: 121 DRGPPHTVDARAGLLQHGLVHLLGIEGRIPHAQLGTRGDVSGGGEVHVAAVLVGRQVLVL 180

Query: 181 GLRRWPHQHHPVAVILVGGVEAHGVPVLLEHLKGKCRLLFPFGDPPGLKGTELCPLDELS 240
           GLRRWPHQHHPVAVILVGGVEAHGVPVLLEHLKGKCRLLFPFGDPPGLKGTELCPLDELS
Sbjct: 181 GLRRWPHQHHPVAVILVGGVEAHGVPVLLEHLKGKCRLLFPFGDPPGLKGTELCPLDELS 240

Query: 241 DGEHPLGSIFQSSDLQLHKADHRALVRFTQSTPWRGCALKDGFNSPWERQCQQVHPWWGC 300
           DGEHPLGSIFQSSDLQLHKADHRALVRFTQSTPWRGCALKDGFNSPWERQCQQVHPWWGC
Sbjct: 241 DGEHPLGSIFQSSDLQLHKADHRALVRFTQSTPWRGCALKDGFNSPWERQCQQVHPWWGC 300

Query: 301 YGTEQGQTGMGSSDGGGTTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVERASFTEDVT 360
           YGTEQGQTGMGSSDGGGTTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVERASFTEDVT
Sbjct: 301 YGTEQGQTGMGSSDGGGTTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVERASFTEDVT 360

Query: 361 SLTEVEECQGLGSGEEGIGAGTSPGHVQDRGGHGVPRAQAPRTEADIGSPEHRPLRQRRT 420
           SLTEVEECQGLGSGEEGIGAGTSPGHVQDRGGHGVPRAQAPRTEADIGSPEHRPLRQRRT
Sbjct: 361 SLTEVEECQGLGSGEEGIGAGTSPGHVQDRGGHGVPRAQAPRTEADIGSPEHRPLRQRRT 420

Query: 421 LGAQSTGPSDRGGHWRQHVPGTITHNTTTTPRELPSSTEATEVRRGVPCPSSPALGHQVA 480
           LGAQSTGPSDRGGHWRQHVPGTITHNTTTTPRELPSSTEATEVRRGVPCPSSPALGHQVA
Sbjct: 421 LGAQSTGPSDRGGHWRQHVPGTITHNTTTTPRELPSSTEATEVRRGVPCPSSPALGHQVA 480

Query: 481 QPPPGEGGTAGQLLPTEPPHQACRDCFWKLLWVSPVPVLITPHPLPRLGVHVSAGRPRPG 540
           QPPPGEGGTAGQLLPTEPPHQACRDCFWKLLWVSPVPVLITPHPLPRLGVHVSAGRPRPG
Sbjct: 481 QPPPGEGGTAGQLLPTEPPHQACRDCFWKLLWVSPVPVLITPHPLPRLGVHVSAGRPRPG 540

Query: 541 MQREANEQTSSLAAGAQHVNHLGKSTLLQPPHTVSGTAGLQLRTLEWIKETHSGALKHVF 600
           MQREANEQTSSLAAGAQHVNHLGKSTLLQPPHTVSGTAGLQLRTLEWIKETHSGALKHVF
Sbjct: 541 MQREANEQTSSLAAGAQHVNHLGKSTLLQPPHTVSGTAGLQLRTLEWIKETHSGALKHVF 600

Query: 601 WCVPAATLLSSQWERNRWLSLRVPLFSLRLLPPRLQTQRPLGSCRSWHMEGPGAHGGHSP 660
           WCVPAATLLSSQWERNRWLSLRVPLFSLRLLPPRLQTQRPLGSCRSWHMEGPGAHGGHSP
Sbjct: 601 WCVPAATLLSSQWERNRWLSLRVPLFSLRLLPPRLQTQRPLGSCRSWHMEGPGAHGGHSP 660

Query: 661 CPA 663
           CPA
Sbjct: 661 CPA 663


>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
          Length = 2382

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 37/151 (24%), Positives = 57/151 (37%), Gaps = 13/151 (8%)

Query: 445 HNTTTTPRELPSSTEATEVRRGVPCPSSPALGHQVAQPPPGEGGTAGQLLPTEPPHQACR 504
           H+T T P  +PS+ +A     GV  PSS A G    QP            P + P Q   
Sbjct: 685 HSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQ-- 742

Query: 505 DCFWKLLWVSPVPVLITPHPLPRLGVHVSAGRPRPGMQREANEQTSSLAAGAQHVNHLGK 564
               + +  +  P     + L +      A   +P  Q +A +    ++AG Q       
Sbjct: 743 ----QGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQ------- 791

Query: 565 STLLQPPHTVSGTAGLQLRTLEWIKETHSGA 595
             + QP  T+ G   + + T   +   HSGA
Sbjct: 792 LPVSQPVPTIQGEPQIPVATQPSVVPVHSGA 822


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 60/225 (26%), Positives = 80/225 (35%), Gaps = 31/225 (13%)

Query: 364 EVEECQGLGSGEEGIGAGTSPGHVQDRGGHGVPRAQAPRTEADIGSPEHRPLRQRRTLGA 423
           E+   +GL +GE    AG  P  +  +G    P  QA       G PE  PL   R+   
Sbjct: 562 ELMAIEGLENGEGPATAG--PRLLTFQGSELSPELQAAMAG---GGPEPLPLPPARSPSQ 616

Query: 424 QSTGPSDRGGHWRQHVPGTITHNTTTTP---RELPSSTEATEVRRGVPCPSSPALGHQVA 480
           +S G   RG    Q  P         +P   R LP  TE    R    C S P  G    
Sbjct: 617 ESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTE----RPPKLCSSLPGQG---- 668

Query: 481 QPPP----GEGGTAGQLLPTEPPHQACRDCFWKLLWVSPVPVLITPHPLPRLGVHVSAGR 536
            PPP       G+     P  PP        W   +++  P      P P+   H S  R
Sbjct: 669 -PPPYVFMYPQGSPSSPAPGPPPGAP-----WAFSYLAGPPATPPDPPRPKRRSH-SLSR 721

Query: 537 PRPGMQREANEQT----SSLAAGAQHVNHLGKSTLLQPPHTVSGT 577
           P P       E      S+L + A      G+S L++   +V+ T
Sbjct: 722 PGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPT 766



 Score = 33.1 bits (74), Expect = 0.84
 Identities = 39/129 (30%), Positives = 50/129 (38%), Gaps = 24/129 (18%)

Query: 448  TTTPRELPSSTEATEVRRGVPCPSSPALGHQVAQPP-PGEGGTAGQLL----PTEPPHQA 502
            ++ P+  PSS  A    +GVP P +P+   Q   PP PG G  +         TEPP   
Sbjct: 952  SSLPQPEPSSLPA----QGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAP 1007

Query: 503  CRDCFWKLLWVSPVPVLIT--------PHPLPRLGVH-------VSAGRPRPGMQREANE 547
                       +P PV +         P   PRLG          S G   PG  ++  E
Sbjct: 1008 AALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVGPGQAQQRLE 1067

Query: 548  QTSSLAAGA 556
            QTSS  A A
Sbjct: 1068 QTSSSLAAA 1076



 Score = 29.6 bits (65), Expect = 9.3
 Identities = 26/91 (28%), Positives = 33/91 (36%), Gaps = 8/91 (8%)

Query: 43  PSICQQVQVLRTPPPLQAPEGAAWL---LTNPPQQHPQRPLSTQPSHGPYWPSPTHLISV 99
           P +    Q   + P    P GA W    L  PP   P  P   + SH    P PT   + 
Sbjct: 671 PYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAE 730

Query: 100 GSAQ-----SQGTITPSARHKGRWAPDRGPP 125
           G A+     + G+     R  GR A  R  P
Sbjct: 731 GEAEGPVGSTLGSYATLTRRPGRSALVRTSP 761


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 60/225 (26%), Positives = 80/225 (35%), Gaps = 31/225 (13%)

Query: 364 EVEECQGLGSGEEGIGAGTSPGHVQDRGGHGVPRAQAPRTEADIGSPEHRPLRQRRTLGA 423
           E+   +GL +GE    AG  P  +  +G    P  QA       G PE  PL   R+   
Sbjct: 644 ELMAIEGLENGEGPATAG--PRLLTFQGSELSPELQAAMAG---GGPEPLPLPPARSPSQ 698

Query: 424 QSTGPSDRGGHWRQHVPGTITHNTTTTP---RELPSSTEATEVRRGVPCPSSPALGHQVA 480
           +S G   RG    Q  P         +P   R LP  TE    R    C S P  G    
Sbjct: 699 ESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTE----RPPKLCSSLPGQG---- 750

Query: 481 QPPP----GEGGTAGQLLPTEPPHQACRDCFWKLLWVSPVPVLITPHPLPRLGVHVSAGR 536
            PPP       G+     P  PP        W   +++  P      P P+   H S  R
Sbjct: 751 -PPPYVFMYPQGSPSSPAPGPPPGAP-----WAFSYLAGPPATPPDPPRPKRRSH-SLSR 803

Query: 537 PRPGMQREANEQT----SSLAAGAQHVNHLGKSTLLQPPHTVSGT 577
           P P       E      S+L + A      G+S L++   +V+ T
Sbjct: 804 PGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPT 848



 Score = 33.1 bits (74), Expect = 0.84
 Identities = 39/129 (30%), Positives = 50/129 (38%), Gaps = 24/129 (18%)

Query: 448  TTTPRELPSSTEATEVRRGVPCPSSPALGHQVAQPP-PGEGGTAGQLL----PTEPPHQA 502
            ++ P+  PSS  A    +GVP P +P+   Q   PP PG G  +         TEPP   
Sbjct: 1034 SSLPQPEPSSLPA----QGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAP 1089

Query: 503  CRDCFWKLLWVSPVPVLIT--------PHPLPRLGVH-------VSAGRPRPGMQREANE 547
                       +P PV +         P   PRLG          S G   PG  ++  E
Sbjct: 1090 AALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVGPGQAQQRLE 1149

Query: 548  QTSSLAAGA 556
            QTSS  A A
Sbjct: 1150 QTSSSLAAA 1158



 Score = 29.6 bits (65), Expect = 9.3
 Identities = 26/91 (28%), Positives = 33/91 (36%), Gaps = 8/91 (8%)

Query: 43  PSICQQVQVLRTPPPLQAPEGAAWL---LTNPPQQHPQRPLSTQPSHGPYWPSPTHLISV 99
           P +    Q   + P    P GA W    L  PP   P  P   + SH    P PT   + 
Sbjct: 753 PYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAE 812

Query: 100 GSAQ-----SQGTITPSARHKGRWAPDRGPP 125
           G A+     + G+     R  GR A  R  P
Sbjct: 813 GEAEGPVGSTLGSYATLTRRPGRSALVRTSP 843


>gi|32479521 dishevelled 1 [Homo sapiens]
          Length = 670

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 35/137 (25%), Positives = 52/137 (37%), Gaps = 17/137 (12%)

Query: 384 PGHVQDRGGHGVPRAQAPRTEADIGSPEHRPLRQ--RRTLGAQSTG-------PSDRGGH 434
           PG     G  G  +++  ++     S    P R+  RR  GA  +G       PS  G  
Sbjct: 531 PGFSYGSGSTGSQQSEGSKSSGSTRSSRRAPGREKERRAAGAGGSGSESDHTAPSGVGSS 590

Query: 435 WRQHVPGTITHNTTTTPRELPSSTEATEVRRGVPCPSSPALGHQVAQPPPGEGGTAGQLL 494
           WR+   G ++    ++PR   S+T       G+P P      + V   PPG G    +L 
Sbjct: 591 WRERPAGQLSRG--SSPRSQASATAP-----GLPPPHPTTKAYTVVGGPPG-GPPVRELA 642

Query: 495 PTEPPHQACRDCFWKLL 511
              P     R  F K +
Sbjct: 643 AVPPELTGSRQSFQKAM 659


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 28/99 (28%), Positives = 41/99 (41%), Gaps = 3/99 (3%)

Query: 299 GCYGTEQGQT-GMGSSDGGGTTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVERASFTE 357
           G Y +  GQT G G  + G    +   +    S    +QG   S + + SS  +  S + 
Sbjct: 336 GHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSR 395

Query: 358 DVTSLTEVEECQ--GLGSGEEGIGAGTSPGHVQDRGGHG 394
             +S  + E       G G+   G+G SPGH Q   G G
Sbjct: 396 QSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSG 434



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 28/96 (29%), Positives = 38/96 (39%), Gaps = 13/96 (13%)

Query: 301 YGTEQGQTGMGSSDGGGTTGNSLLRSHMKSTPR--KTQGPWKSQTERVSSQVERASFTED 358
           +G  +  +G G S  G  +G      H  S  R   T G   S  +  SS  + +S+ + 
Sbjct: 817 FGQHESGSGQGYSQHGSASG------HFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQH 870

Query: 359 VTSLTEVEECQGLGSGEEGIGAGTSPGHVQDRGGHG 394
                E       G G  G G+G SPGH Q   G G
Sbjct: 871 -----ESASHHASGRGRHGSGSGQSPGHGQRGSGSG 901



 Score = 33.1 bits (74), Expect = 0.84
 Identities = 64/298 (21%), Positives = 98/298 (32%), Gaps = 43/298 (14%)

Query: 240  SDGEHPLGSIFQSSDLQLHKADHRALVRFTQSTPWRGCALKDGFNSPWERQCQQVHPWWG 299
            S G+H   S   SS  Q   A H A  R    +   G     G         Q   P +G
Sbjct: 853  SSGQHDSSSGQSSSYGQHESASHHASGRGRHGS---GSGQSPGHGQRGSGSGQS--PSYG 907

Query: 300  CYGTEQGQTGMGSSDGGGTTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVERASFTEDV 359
             +G+  G++      G G+ G S    H  S+ + +           SS  E+       
Sbjct: 908  RHGSGSGRSSSSGRHGSGS-GQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQ 966

Query: 360  TSLTEVEEC----------------QGLGSGEEGIGAGTSPGHVQDRGGHGVPRA----- 398
            +S +E                    Q LG G+ G G+G SP   + R G G  ++     
Sbjct: 967  SSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGP 1026

Query: 399  -------QAPRTEADIGSPEHRPLRQRRTLGAQSTGPSDRG---GHWRQHVP--GTITHN 446
                    + R   + GS     L  R +   QS+G    G   GH   H     T   +
Sbjct: 1027 YRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 1086

Query: 447  TTTTPRELPSSTEATEVRRGVPCPSSPALGHQVA----QPPPGEGGTAGQLLPTEPPH 500
            ++       S   ++  + G     S   G Q +     P  G+ G+  +  P+   H
Sbjct: 1087 SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 1144



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 38/148 (25%), Positives = 53/148 (35%), Gaps = 25/148 (16%)

Query: 303  TEQGQTGMGSSDGGG----------TTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVER 352
            +  GQ G GSS   G          + G+    S  + +P  + G   S + R SS  + 
Sbjct: 1100 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSP--SYGRHGSGSGRSSSSGQH 1157

Query: 353  ASFTEDVTSLTEVEECQGLGSGEEGIGAGTSPGHVQDRGGHGVPRAQAPRTE---ADIGS 409
             S   + +     E   G  S     G+G+  GH    G HG    Q+ R E   +  GS
Sbjct: 1158 GSGLGESSGFGHHESSSGQSSSYSQHGSGS--GHSSGYGQHGSRSGQSSRGERHGSSSGS 1215

Query: 410  PEHRPLRQRRTLGAQSTGPSDRGGHWRQ 437
              H         G   +G     GH RQ
Sbjct: 1216 SSH--------YGQHGSGSRQSSGHGRQ 1235



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 37/145 (25%), Positives = 51/145 (35%), Gaps = 19/145 (13%)

Query: 303  TEQGQTGMGSSDGGG----------TTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVER 352
            +  GQ G GSS   G          + G+    S  + +P  + G   S + R SS  + 
Sbjct: 1570 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSP--SYGRHGSGSGRSSSSGQH 1627

Query: 353  ASFTEDVTSLTEVEECQGLGSGEEGIGAGTSPGHVQDRGGHGVPRAQAPRTEADIGSPEH 412
             S   + +     E   G  S     G+G+  GH    G HG    Q+ R E    S   
Sbjct: 1628 GSGLGESSGFGHHESSSGQSSSYSQHGSGS--GHSSGYGQHGSRSGQSSRGERHGSSS-- 1683

Query: 413  RPLRQRRTLGAQSTGPSDRGGHWRQ 437
               R     G   +G     GH RQ
Sbjct: 1684 ---RSSSRYGQHGSGSRQSSGHGRQ 1705



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 38/148 (25%), Positives = 53/148 (35%), Gaps = 25/148 (16%)

Query: 303  TEQGQTGMGSSDGGG----------TTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVER 352
            +  GQ G GSS   G          + G+    S  + +P  + G   S + R SS  + 
Sbjct: 2510 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSP--SYGRHGSGSGRSSSSGQH 2567

Query: 353  ASFTEDVTSLTEVEECQGLGSGEEGIGAGTSPGHVQDRGGHGVPRAQAPRTE---ADIGS 409
             S   + +     E   G  S     G+G+  GH    G HG    Q+ R E   +  GS
Sbjct: 2568 GSGLGESSGFGHHESSSGQSSSYSQHGSGS--GHSSGYGQHGSRSGQSSRGERHGSSSGS 2625

Query: 410  PEHRPLRQRRTLGAQSTGPSDRGGHWRQ 437
              H         G   +G     GH RQ
Sbjct: 2626 SSH--------YGQHGSGSRQSSGHGRQ 2645



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 36/163 (22%), Positives = 60/163 (36%), Gaps = 26/163 (15%)

Query: 296 PWWGCYGTEQGQTGMGSSDGGGTTGNSLLRSHMKSTPRKT--------------QGPWKS 341
           P +G +G+  GQ+    + G G+  +S    H  S+ + +               G   S
Sbjct: 203 PNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGS 262

Query: 342 QTERVSSQVERASFTEDVTSLTE--VEECQGLGSGEEGIGAGTSPGHVQDRGGHGVPRAQ 399
           ++ + S      S +   +S  +      Q LG G +G G+  SP HV+   G G   + 
Sbjct: 263 RSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSH 322

Query: 400 A----------PRTEADIGSPEHRPLRQRRTLGAQSTGPSDRG 432
                       R   + GS +     Q  +   QS+G S  G
Sbjct: 323 GQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHG 365



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 25/91 (27%), Positives = 37/91 (40%), Gaps = 5/91 (5%)

Query: 302  GTEQGQTGMGSSDGGGTTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVERASFTEDVTS 361
            G    ++  G S G G  G+S   S        T G   S  +  +S  + +S  +  + 
Sbjct: 1519 GLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSG 1578

Query: 362  LTEVEECQGLGSGEEGIGAGTSPGHVQDRGG 392
             +     Q  G G +G G+G SPGH Q   G
Sbjct: 1579 SS-----QSSGYGRQGSGSGQSPGHGQRGSG 1604



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 25/91 (27%), Positives = 37/91 (40%), Gaps = 5/91 (5%)

Query: 302  GTEQGQTGMGSSDGGGTTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVERASFTEDVTS 361
            G    ++  G S G G  G+S   S        T G   S  +  +S  + +S  +  + 
Sbjct: 2459 GLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSG 2518

Query: 362  LTEVEECQGLGSGEEGIGAGTSPGHVQDRGG 392
             +     Q  G G +G G+G SPGH Q   G
Sbjct: 2519 SS-----QSSGYGRQGSGSGQSPGHGQRGSG 2544



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 15/114 (13%)

Query: 330 STPRKTQGPWKSQTERVSSQV--------ERASFTEDVTSLTEV--EECQGLGSGEEGIG 379
           S  R  +G  K  TE +S ++        +  S++   +S  E   +  Q  G G+ G G
Sbjct: 139 SYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSG 198

Query: 380 AGTSPGHVQDRGGHGVPRAQAPRTEA-DIGSPEHRPLRQRRTLGAQSTGPSDRG 432
           +G SP +    G HG    Q+   +    GS +     Q ++   QS+G S  G
Sbjct: 199 SGQSPNY----GQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHG 248



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 35/153 (22%), Positives = 55/153 (35%), Gaps = 21/153 (13%)

Query: 369  QGLGSGEEGIGAGTSPGHVQDRGGHGVPRA------------QAPRTEADIGSPEHRPLR 416
            Q LG G+ G G+G SP   + R G G  ++             + R   + GS     L 
Sbjct: 1462 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLG 1521

Query: 417  QRRTLGAQSTGPSDRG---GHWRQHVP--GTITHNTTTTPRELPSSTEATEVRRGVPCPS 471
             R +   QS+G    G   GH   H     T   +++       S   ++  + G     
Sbjct: 1522 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQ 1581

Query: 472  SPALGHQVA----QPPPGEGGTAGQLLPTEPPH 500
            S   G Q +     P  G+ G+  +  P+   H
Sbjct: 1582 SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 1614



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 35/153 (22%), Positives = 55/153 (35%), Gaps = 21/153 (13%)

Query: 369  QGLGSGEEGIGAGTSPGHVQDRGGHGVPRA------------QAPRTEADIGSPEHRPLR 416
            Q LG G+ G G+G SP   + R G G  ++             + R   + GS     L 
Sbjct: 2402 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLG 2461

Query: 417  QRRTLGAQSTGPSDRG---GHWRQHVP--GTITHNTTTTPRELPSSTEATEVRRGVPCPS 471
             R +   QS+G    G   GH   H     T   +++       S   ++  + G     
Sbjct: 2462 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQ 2521

Query: 472  SPALGHQVA----QPPPGEGGTAGQLLPTEPPH 500
            S   G Q +     P  G+ G+  +  P+   H
Sbjct: 2522 SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2554



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 24/85 (28%), Positives = 33/85 (38%), Gaps = 15/85 (17%)

Query: 369  QGLGSGEEGIGAGTSPGHVQDRGGHGVPRA------------QAPRTEADIGSPEHRPLR 416
            Q LG G+ G G+G SP   + R G G  ++             + R   + GS     L 
Sbjct: 1932 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLG 1991

Query: 417  QRRTLGAQSTGPSDRG---GHWRQH 438
             R +   QS+G    G   GH   H
Sbjct: 1992 HRESRSGQSSGYGQHGSSSGHSSTH 2016



 Score = 29.6 bits (65), Expect = 9.3
 Identities = 25/106 (23%), Positives = 41/106 (38%), Gaps = 19/106 (17%)

Query: 298  WGCYGTEQGQTGMGSSDGGGTTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVERASFTE 357
            +G + +  GQ+   S  G G+  +S    H   + + ++G     + R SS+  +     
Sbjct: 1637 FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGS 1696

Query: 358  DVTSLTEVEECQGLGSGEEGIGAGTSP---------GHVQDRGGHG 394
              +S          G G +G G+G SP         GH    G HG
Sbjct: 1697 RQSS----------GHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHG 1732



 Score = 29.6 bits (65), Expect = 9.3
 Identities = 24/91 (26%), Positives = 36/91 (39%), Gaps = 5/91 (5%)

Query: 302  GTEQGQTGMGSSDGGGTTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVERASFTEDVTS 361
            G    ++  G S G G  G+S   S          G   S  +  +S  + +S  +  + 
Sbjct: 1989 GLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSG 2048

Query: 362  LTEVEECQGLGSGEEGIGAGTSPGHVQDRGG 392
             +     Q  G G +G G+G SPGH Q   G
Sbjct: 2049 SS-----QSSGYGRQGSGSGQSPGHGQRGSG 2074


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score = 37.0 bits (84), Expect = 0.058
 Identities = 99/404 (24%), Positives = 131/404 (32%), Gaps = 84/404 (20%)

Query: 59   QAPEGAAWLLTNPPQQHPQRPLSTQPS-HGPYWPSPTHLISVGSAQSQGTITPSARHKGR 117
            Q P+G    L  P   H  + +   P  HGP  P        G    QG+  P    +G 
Sbjct: 656  QGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQ-------GPPGPQGSSGP----QGH 704

Query: 118  WAPDRGPPHTVDARAGLLQHGLVHLLGIEGRIPHAQLGTRGDVSGGGEVHVAAVLVGRQV 177
              P +GPP            G +   G  G  P   LG +G     G             
Sbjct: 705  MGP-QGPPGP---------QGHIGPQGPPG--PQGHLGPQGPPGTQGMQGPPGPR----- 747

Query: 178  LVLGLRRWPHQHHPVAVILVGGVEAHGV--PVLLEHLKGKCRLLFPFG--DPPGLK---- 229
               G++  PH H      + GG  + G+  PV    L G    L P G   PPG +    
Sbjct: 748  ---GMQGPPHPHG-----IQGGPGSQGIQGPVSQGPLMG----LNPRGMQGPPGPRENQG 795

Query: 230  ----GTELCPLDELSDGEHPLGSIFQSSDLQLHKADHRALVRFTQSTPWRGCAL--KDGF 283
                G  +    +   G HP G +      ++        +R  Q  P +G  L      
Sbjct: 796  PAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQE---IRGMQGPPPQGSMLGPPQEL 852

Query: 284  NSPWERQCQQVHPWWGCYGTEQGQTGMGSSDGGGTTGNSLLRSHMKST--PRKTQGP--W 339
              P   Q QQ  P          Q  +G    GG  G    +        P  +QGP  +
Sbjct: 853  RGPPGSQSQQGPP----------QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPF 902

Query: 340  KSQTERVSSQVERASFTEDVTSLTEVEECQGLGS-GEEGI------GAGTSPGHVQDRGG 392
            + Q   +     RA F ++  S        GLG  G +G       G G  P     RG 
Sbjct: 903  QQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGP 962

Query: 393  ---HGVPRAQAPRTEADIGSPEHRPLRQRRTLGAQSTGPSDRGG 433
               H  P ++  R     G PEH P R     G    GP DR G
Sbjct: 963  PNHHMGPMSE--RRHEQSGGPEHGPERGPFRGGQDCRGPPDRRG 1004


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 36.6 bits (83), Expect = 0.076
 Identities = 35/119 (29%), Positives = 44/119 (36%), Gaps = 17/119 (14%)

Query: 383  SPGHVQDRGGHGVPRAQAPRTEADIGSPEHRPLRQRRTLGAQSTGPSDRGGHWRQHVPGT 442
            SP       G   P A  P +    GSP   PL +       +T PS +GG     + G 
Sbjct: 1022 SPAATPFPKGASTPPAATPPSPK--GSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079

Query: 443  ITHNTTTTPRELPSSTEATEVRRGVPCPSSPALGHQVAQPPPGEGGTAGQLLPTEPPHQ 501
             T    T P   P    AT   +G P P +       A PP  +GG A       PPH+
Sbjct: 1080 PTPPAATPPS--PKGGPATPSPKGAPMPPA-------ATPPSPKGGLA------TPPHK 1123


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 36.2 bits (82), Expect = 0.099
 Identities = 41/176 (23%), Positives = 61/176 (34%), Gaps = 16/176 (9%)

Query: 315 GGGTTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVERASFTEDVTSLTEVEECQGLGSG 374
           GG   G +  R   +   R+++    +   R   +   A       SL+        GSG
Sbjct: 376 GGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSG 435

Query: 375 EEGIGAGTSPGHVQDRGGHGVPRAQAPRTEADIGSPEHRPLRQRRTLGAQST--GPSDRG 432
               G G  PG  +  GGHG    + P        P  RP     + GA     GP    
Sbjct: 436 RGAPGPGPEPGSERGHGGHGKRAKERP--------PRARPASTSPSPGAHGRRGGPE--- 484

Query: 433 GHWRQHVPGTITHNTTTTPRELPSSTEATEVRRGVPCPS-SPALGHQVAQPPPGEG 487
           G      PG   H  + +    PS + +    +    PS SP+    +++   GEG
Sbjct: 485 GKSSSRSPG--PHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEG 538


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 36.2 bits (82), Expect = 0.099
 Identities = 30/92 (32%), Positives = 36/92 (39%), Gaps = 12/92 (13%)

Query: 36  QDVSSAAPSICQQVQVLRTPPPLQAPEGAAWLLTNPPQQHPQRPLSTQPSHGPYWPSPTH 95
           QD  S + S  QQ  +   PP LQAP G     ++ P   PQ P           P PT 
Sbjct: 165 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT----------PGPTP 214

Query: 96  LISVGSAQSQGTITPSARHKGRWAPDRGPPHT 127
             S  +   QG+ T S       AP    PHT
Sbjct: 215 --SATAVPPQGSPTASQAPNQPQAPTAPVPHT 244



 Score = 29.6 bits (65), Expect = 9.3
 Identities = 28/81 (34%), Positives = 32/81 (39%), Gaps = 2/81 (2%)

Query: 14  TLSSWCPPNTLLLGLMLSPMKIQDVSSAA-PSICQQVQVLRTPPPLQAPEGAAWLLTNPP 72
           +LS+  PP+     L L P      SS A P    Q Q L  PP    P G   +   PP
Sbjct: 420 SLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPP 479

Query: 73  -QQHPQRPLSTQPSHGPYWPS 92
             QHP  P    P   P  PS
Sbjct: 480 FAQHPFVPGGPPPITPPTCPS 500


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 36.2 bits (82), Expect = 0.099
 Identities = 30/92 (32%), Positives = 36/92 (39%), Gaps = 12/92 (13%)

Query: 36  QDVSSAAPSICQQVQVLRTPPPLQAPEGAAWLLTNPPQQHPQRPLSTQPSHGPYWPSPTH 95
           QD  S + S  QQ  +   PP LQAP G     ++ P   PQ P           P PT 
Sbjct: 719 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT----------PGPTP 768

Query: 96  LISVGSAQSQGTITPSARHKGRWAPDRGPPHT 127
             S  +   QG+ T S       AP    PHT
Sbjct: 769 --SATAVPPQGSPTASQAPNQPQAPTAPVPHT 798



 Score = 29.6 bits (65), Expect = 9.3
 Identities = 28/81 (34%), Positives = 32/81 (39%), Gaps = 2/81 (2%)

Query: 14   TLSSWCPPNTLLLGLMLSPMKIQDVSSAA-PSICQQVQVLRTPPPLQAPEGAAWLLTNPP 72
            +LS+  PP+     L L P      SS A P    Q Q L  PP    P G   +   PP
Sbjct: 974  SLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPP 1033

Query: 73   -QQHPQRPLSTQPSHGPYWPS 92
              QHP  P    P   P  PS
Sbjct: 1034 FAQHPFVPGGPPPITPPTCPS 1054


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 36.2 bits (82), Expect = 0.099
 Identities = 30/92 (32%), Positives = 36/92 (39%), Gaps = 12/92 (13%)

Query: 36  QDVSSAAPSICQQVQVLRTPPPLQAPEGAAWLLTNPPQQHPQRPLSTQPSHGPYWPSPTH 95
           QD  S + S  QQ  +   PP LQAP G     ++ P   PQ P           P PT 
Sbjct: 719 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT----------PGPTP 768

Query: 96  LISVGSAQSQGTITPSARHKGRWAPDRGPPHT 127
             S  +   QG+ T S       AP    PHT
Sbjct: 769 --SATAVPPQGSPTASQAPNQPQAPTAPVPHT 798



 Score = 29.6 bits (65), Expect = 9.3
 Identities = 28/81 (34%), Positives = 32/81 (39%), Gaps = 2/81 (2%)

Query: 14   TLSSWCPPNTLLLGLMLSPMKIQDVSSAA-PSICQQVQVLRTPPPLQAPEGAAWLLTNPP 72
            +LS+  PP+     L L P      SS A P    Q Q L  PP    P G   +   PP
Sbjct: 974  SLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPP 1033

Query: 73   -QQHPQRPLSTQPSHGPYWPS 92
              QHP  P    P   P  PS
Sbjct: 1034 FAQHPFVPGGPPPITPPTCPS 1054


>gi|239757861 PREDICTED: similar to armadillo repeat containing,
            X-linked 4 [Homo sapiens]
          Length = 2382

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 41/152 (26%), Positives = 59/152 (38%), Gaps = 18/152 (11%)

Query: 287  WERQCQQVHPWWG-CYGTEQGQTGMGSSDGGGTTGNSLLRSHMKSTPRKTQGPWKSQTER 345
            W     Q   W+  C G+   QT  GS   GG +G  +  S    T + + G W S   +
Sbjct: 1591 WAGTGDQASGWFCVCPGS---QTNGGS--WGGASGQDVGGSRPGPTNQSSAGSWDSPGSQ 1645

Query: 346  VSSQVERASFTEDVTSLTEVEECQGLGSGEEGIGAGTSPGHVQDRGGHGVPRAQAPRTEA 405
            VS      +   D     +   C   G  ++ IG G  PG     GG   P ++     +
Sbjct: 1646 VSGSCWTGAGAVD-----QAGGCSKPGFEDQAIGGGFWPGAGDQTGGGSRPGSE--DQSS 1698

Query: 406  DIGSPEHRPLRQRRTLGAQSTGPSDR--GGHW 435
             IGS     +   + LG    GP+D+  GG W
Sbjct: 1699 GIGS---WGVAGGQVLGGARPGPADQSSGGSW 1727


>gi|239754873 PREDICTED: similar to hCG2040393 [Homo sapiens]
          Length = 333

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 30/110 (27%), Positives = 35/110 (31%), Gaps = 25/110 (22%)

Query: 390 RGGHGVPRAQAPRTEADIGSPEHRPLRQRRTLGAQSTGPSDRGGHWRQHVPGTITHNTTT 449
           R GH  PR Q P+       P   PL                        PG +T  +  
Sbjct: 57  RPGHTAPRTQQPKPSGPSSHPREPPL------------------------PGAVTGGSLH 92

Query: 450 TPRELPSSTEATEVRRGVPCPSSPALGHQVAQPPPGEGGTAGQLLPTEPP 499
             +E P    AT   R    P SP   H+   PPPG     G     EPP
Sbjct: 93  F-QEPPPLGAATAGSRHRQKPPSPGSRHRWEPPPPGAATATGSRHRREPP 141


>gi|239749412 PREDICTED: hypothetical protein XP_002347031 [Homo
           sapiens]
          Length = 333

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 30/110 (27%), Positives = 35/110 (31%), Gaps = 25/110 (22%)

Query: 390 RGGHGVPRAQAPRTEADIGSPEHRPLRQRRTLGAQSTGPSDRGGHWRQHVPGTITHNTTT 449
           R GH  PR Q P+       P   PL                        PG +T  +  
Sbjct: 57  RPGHTAPRTQQPKPSGPSSHPREPPL------------------------PGAVTGGSLH 92

Query: 450 TPRELPSSTEATEVRRGVPCPSSPALGHQVAQPPPGEGGTAGQLLPTEPP 499
             +E P    AT   R    P SP   H+   PPPG     G     EPP
Sbjct: 93  F-QEPPPLGAATAGSRHRQKPPSPGSRHRWEPPPPGAATATGSRHRREPP 141


>gi|239743547 PREDICTED: hypothetical protein XP_002342883 [Homo
           sapiens]
          Length = 333

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 30/110 (27%), Positives = 35/110 (31%), Gaps = 25/110 (22%)

Query: 390 RGGHGVPRAQAPRTEADIGSPEHRPLRQRRTLGAQSTGPSDRGGHWRQHVPGTITHNTTT 449
           R GH  PR Q P+       P   PL                        PG +T  +  
Sbjct: 57  RPGHTAPRTQQPKPSGPSSHPREPPL------------------------PGAVTGGSLH 92

Query: 450 TPRELPSSTEATEVRRGVPCPSSPALGHQVAQPPPGEGGTAGQLLPTEPP 499
             +E P    AT   R    P SP   H+   PPPG     G     EPP
Sbjct: 93  F-QEPPPLGAATAGSRHRQKPPSPGSRHRWEPPPPGAATATGSRHRREPP 141


>gi|38373682 pleckstrin homology domain containing family G member 5
           isoform a [Homo sapiens]
          Length = 1006

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 52/192 (27%), Positives = 75/192 (39%), Gaps = 20/192 (10%)

Query: 330 STPRKTQGPWKSQTERVSSQVERASFTEDVTSLTEVEECQGLGSGEEGIGAGTSPGHVQD 389
           S+P    GP+ SQ++  S     +S T   + L  +    G     +      SP  +QD
Sbjct: 771 SSPEFDSGPFSSQSDETSLSTTASSAT-PTSELLPLGPVDGRSCSMDSAYGTLSPTSLQD 829

Query: 390 RGGHG-----VPRA-QAPRTEADIGSPEHRPLRQRRTLGAQSTGP----SDRGGHWRQHV 439
               G     VPRA ++PR  +   SP    LR+R  +   S  P    S       Q +
Sbjct: 830 FVAPGPMAELVPRAPESPRVPSPPPSPR---LRRRTPVQLLSCPPHLLKSKSEASLLQLL 886

Query: 440 PGTITHNTTTTP----RELPSSTEATEVR-RGVPCPSSPALGHQVAQPPPGEGGTAGQLL 494
            G  TH T + P     EL  +  A  +R +G P  + P+   + A P PG G      L
Sbjct: 887 AGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGA-PSPGSGPGLVGCL 945

Query: 495 PTEPPHQACRDC 506
             EP     + C
Sbjct: 946 AGEPAGSHRKRC 957


>gi|111154084 pleckstrin homology domain containing family G member 5
            isoform b [Homo sapiens]
          Length = 1083

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 52/192 (27%), Positives = 75/192 (39%), Gaps = 20/192 (10%)

Query: 330  STPRKTQGPWKSQTERVSSQVERASFTEDVTSLTEVEECQGLGSGEEGIGAGTSPGHVQD 389
            S+P    GP+ SQ++  S     +S T   + L  +    G     +      SP  +QD
Sbjct: 848  SSPEFDSGPFSSQSDETSLSTTASSAT-PTSELLPLGPVDGRSCSMDSAYGTLSPTSLQD 906

Query: 390  RGGHG-----VPRA-QAPRTEADIGSPEHRPLRQRRTLGAQSTGP----SDRGGHWRQHV 439
                G     VPRA ++PR  +   SP    LR+R  +   S  P    S       Q +
Sbjct: 907  FVAPGPMAELVPRAPESPRVPSPPPSPR---LRRRTPVQLLSCPPHLLKSKSEASLLQLL 963

Query: 440  PGTITHNTTTTP----RELPSSTEATEVR-RGVPCPSSPALGHQVAQPPPGEGGTAGQLL 494
             G  TH T + P     EL  +  A  +R +G P  + P+   + A P PG G      L
Sbjct: 964  AGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGA-PSPGSGPGLVGCL 1022

Query: 495  PTEPPHQACRDC 506
              EP     + C
Sbjct: 1023 AGEPAGSHRKRC 1034


>gi|111154088 pleckstrin homology domain containing family G member
           5 isoform a [Homo sapiens]
          Length = 1006

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 52/192 (27%), Positives = 75/192 (39%), Gaps = 20/192 (10%)

Query: 330 STPRKTQGPWKSQTERVSSQVERASFTEDVTSLTEVEECQGLGSGEEGIGAGTSPGHVQD 389
           S+P    GP+ SQ++  S     +S T   + L  +    G     +      SP  +QD
Sbjct: 771 SSPEFDSGPFSSQSDETSLSTTASSAT-PTSELLPLGPVDGRSCSMDSAYGTLSPTSLQD 829

Query: 390 RGGHG-----VPRA-QAPRTEADIGSPEHRPLRQRRTLGAQSTGP----SDRGGHWRQHV 439
               G     VPRA ++PR  +   SP    LR+R  +   S  P    S       Q +
Sbjct: 830 FVAPGPMAELVPRAPESPRVPSPPPSPR---LRRRTPVQLLSCPPHLLKSKSEASLLQLL 886

Query: 440 PGTITHNTTTTP----RELPSSTEATEVR-RGVPCPSSPALGHQVAQPPPGEGGTAGQLL 494
            G  TH T + P     EL  +  A  +R +G P  + P+   + A P PG G      L
Sbjct: 887 AGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGA-PSPGSGPGLVGCL 945

Query: 495 PTEPPHQACRDC 506
             EP     + C
Sbjct: 946 AGEPAGSHRKRC 957


>gi|111154080 pleckstrin homology domain containing family G member
           5 isoform a [Homo sapiens]
          Length = 1006

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 52/192 (27%), Positives = 75/192 (39%), Gaps = 20/192 (10%)

Query: 330 STPRKTQGPWKSQTERVSSQVERASFTEDVTSLTEVEECQGLGSGEEGIGAGTSPGHVQD 389
           S+P    GP+ SQ++  S     +S T   + L  +    G     +      SP  +QD
Sbjct: 771 SSPEFDSGPFSSQSDETSLSTTASSAT-PTSELLPLGPVDGRSCSMDSAYGTLSPTSLQD 829

Query: 390 RGGHG-----VPRA-QAPRTEADIGSPEHRPLRQRRTLGAQSTGP----SDRGGHWRQHV 439
               G     VPRA ++PR  +   SP    LR+R  +   S  P    S       Q +
Sbjct: 830 FVAPGPMAELVPRAPESPRVPSPPPSPR---LRRRTPVQLLSCPPHLLKSKSEASLLQLL 886

Query: 440 PGTITHNTTTTP----RELPSSTEATEVR-RGVPCPSSPALGHQVAQPPPGEGGTAGQLL 494
            G  TH T + P     EL  +  A  +R +G P  + P+   + A P PG G      L
Sbjct: 887 AGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGA-PSPGSGPGLVGCL 945

Query: 495 PTEPPHQACRDC 506
             EP     + C
Sbjct: 946 AGEPAGSHRKRC 957


>gi|111154078 pleckstrin homology domain containing family G member 5
            isoform c [Homo sapiens]
          Length = 1062

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 52/192 (27%), Positives = 75/192 (39%), Gaps = 20/192 (10%)

Query: 330  STPRKTQGPWKSQTERVSSQVERASFTEDVTSLTEVEECQGLGSGEEGIGAGTSPGHVQD 389
            S+P    GP+ SQ++  S     +S T   + L  +    G     +      SP  +QD
Sbjct: 827  SSPEFDSGPFSSQSDETSLSTTASSAT-PTSELLPLGPVDGRSCSMDSAYGTLSPTSLQD 885

Query: 390  RGGHG-----VPRA-QAPRTEADIGSPEHRPLRQRRTLGAQSTGP----SDRGGHWRQHV 439
                G     VPRA ++PR  +   SP    LR+R  +   S  P    S       Q +
Sbjct: 886  FVAPGPMAELVPRAPESPRVPSPPPSPR---LRRRTPVQLLSCPPHLLKSKSEASLLQLL 942

Query: 440  PGTITHNTTTTP----RELPSSTEATEVR-RGVPCPSSPALGHQVAQPPPGEGGTAGQLL 494
             G  TH T + P     EL  +  A  +R +G P  + P+   + A P PG G      L
Sbjct: 943  AGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGA-PSPGSGPGLVGCL 1001

Query: 495  PTEPPHQACRDC 506
              EP     + C
Sbjct: 1002 AGEPAGSHRKRC 1013


>gi|239753475 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 721

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 27/108 (25%), Positives = 44/108 (40%), Gaps = 11/108 (10%)

Query: 477 HQVAQPP-----PGEGGTAGQLLPTEPPHQACRDCFWKLLWVSPVPVLITPHPLPRLGVH 531
           H+  +PP     PG   T+ +   +EPP   C        W+S +P   T     R G+H
Sbjct: 214 HEAQKPPKHTAPPGPDLTSIRTPASEPPVTGCHPPSGGCGWISRLPRTWTRVAASRWGLH 273

Query: 532 VSAGRPRPGMQREANEQTSSLAAGAQHVNHLGKSTLLQPPHTVSGTAG 579
           +  G      QR +       ++G   ++HL  ++ + PP    G  G
Sbjct: 274 MGWG------QRPSTVLLPLPSSGRPCLHHLSPTSSILPPQAPGGAPG 315


>gi|239748044 PREDICTED: hypothetical protein XP_002346500 [Homo
           sapiens]
          Length = 721

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 27/108 (25%), Positives = 44/108 (40%), Gaps = 11/108 (10%)

Query: 477 HQVAQPP-----PGEGGTAGQLLPTEPPHQACRDCFWKLLWVSPVPVLITPHPLPRLGVH 531
           H+  +PP     PG   T+ +   +EPP   C        W+S +P   T     R G+H
Sbjct: 214 HEAQKPPKHTAPPGPDLTSIRTPASEPPVTGCHPPSGGCGWISRLPRTWTRVAASRWGLH 273

Query: 532 VSAGRPRPGMQREANEQTSSLAAGAQHVNHLGKSTLLQPPHTVSGTAG 579
           +  G      QR +       ++G   ++HL  ++ + PP    G  G
Sbjct: 274 MGWG------QRPSTVLLPLPSSGRPCLHHLSPTSSILPPQAPGGAPG 315


>gi|239741935 PREDICTED: hypothetical protein XP_002342357 [Homo
           sapiens]
          Length = 721

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 27/108 (25%), Positives = 44/108 (40%), Gaps = 11/108 (10%)

Query: 477 HQVAQPP-----PGEGGTAGQLLPTEPPHQACRDCFWKLLWVSPVPVLITPHPLPRLGVH 531
           H+  +PP     PG   T+ +   +EPP   C        W+S +P   T     R G+H
Sbjct: 214 HEAQKPPKHTAPPGPDLTSIRTPASEPPVTGCHPPSGGCGWISRLPRTWTRVAASRWGLH 273

Query: 532 VSAGRPRPGMQREANEQTSSLAAGAQHVNHLGKSTLLQPPHTVSGTAG 579
           +  G      QR +       ++G   ++HL  ++ + PP    G  G
Sbjct: 274 MGWG------QRPSTVLLPLPSSGRPCLHHLSPTSSILPPQAPGGAPG 315


>gi|38016904 thrombospondin repeat containing 1 isoform 1 [Homo
           sapiens]
          Length = 1074

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 45/147 (30%), Positives = 58/147 (39%), Gaps = 22/147 (14%)

Query: 374 GEEGIGAGTSPGHVQDRGGHGVPRAQAPRTEADIG--SPEHRPLRQR--RTLGAQSTGPS 429
           GEE I + T     +    +G P+ + P TE  +   SP+  PL     +T  A  T P+
Sbjct: 190 GEEAIPSPTP--RAEPFSANGSPQTELPPTELSVHTPSPQAEPLSPETAQTEVAPRTRPA 247

Query: 430 DRGGHWRQHVPGTI----THN--------TTTTPRELPSSTEATEV---RRGVPCPSSPA 474
               H R    GT     TH+         +  PR   S   A+     RR  P PS P 
Sbjct: 248 PLRHHPRAQASGTEPPSPTHSLGEGGFFRASPQPRRPSSQGWASPQVAGRRPDPFPSVPR 307

Query: 475 LGHQVAQPPPGEGGTA-GQLLPTEPPH 500
              Q  Q P G GGT  G  L  +P H
Sbjct: 308 GRGQQGQGPWGTGGTPHGPRLEPDPQH 334


>gi|56788359 thrombospondin repeat containing 1 isoform 2 [Homo
           sapiens]
          Length = 877

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 45/147 (30%), Positives = 58/147 (39%), Gaps = 22/147 (14%)

Query: 374 GEEGIGAGTSPGHVQDRGGHGVPRAQAPRTEADIG--SPEHRPLRQR--RTLGAQSTGPS 429
           GEE I + T     +    +G P+ + P TE  +   SP+  PL     +T  A  T P+
Sbjct: 190 GEEAIPSPTP--RAEPFSANGSPQTELPPTELSVHTPSPQAEPLSPETAQTEVAPRTRPA 247

Query: 430 DRGGHWRQHVPGTI----THN--------TTTTPRELPSSTEATEV---RRGVPCPSSPA 474
               H R    GT     TH+         +  PR   S   A+     RR  P PS P 
Sbjct: 248 PLRHHPRAQASGTEPPSPTHSLGEGGFFRASPQPRRPSSQGWASPQVAGRRPDPFPSVPR 307

Query: 475 LGHQVAQPPPGEGGTA-GQLLPTEPPH 500
              Q  Q P G GGT  G  L  +P H
Sbjct: 308 GRGQQGQGPWGTGGTPHGPRLEPDPQH 334


>gi|30039694 zinc finger protein 598 [Homo sapiens]
          Length = 904

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 16/74 (21%)

Query: 455 PSSTEATEVRRGVPCPSSPALGHQVAQPPPGEGGTAGQLLPTEPPHQACRDCFWKLLWVS 514
           P    A  + +G P P  P L   +++PPPG  G    LLP+  PH AC           
Sbjct: 683 PPGFSAVVLLKGTPPPPPPGLVPPISKPPPGFSG----LLPS--PHPAC----------V 726

Query: 515 PVPVLITPHPLPRL 528
           P P   T    PRL
Sbjct: 727 PSPATTTTTKAPRL 740


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score = 35.0 bits (79), Expect = 0.22
 Identities = 31/139 (22%), Positives = 52/139 (37%), Gaps = 12/139 (8%)

Query: 298 WGCYGTEQGQTGMGSSDGGGTTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVERASFTE 357
           +G YG+  GQ+      G G+  +S    H   + + + G   S + + S   +  S + 
Sbjct: 807 FGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSG 866

Query: 358 DVTSLTEVEECQG--LGSGEEGIGAGTSPGHVQDRGGHGVPRAQAPRTEADIGSPEHRPL 415
             +   +     G   G G+ G G+G S G     G HG    Q        G  +H   
Sbjct: 867 QTSGFGQHRSSSGQYSGFGQHGSGSGQSSGF----GQHGTGSGQYS------GFGQHESR 916

Query: 416 RQRRTLGAQSTGPSDRGGH 434
             + + G   +G S   G+
Sbjct: 917 SHQSSYGQHGSGSSQSSGY 935



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 29/137 (21%), Positives = 48/137 (35%), Gaps = 10/137 (7%)

Query: 298 WGCYGTEQGQTGMGSSDGGGTTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVERASFTE 357
           +G +G+  GQ+      G G+  +S    H   + + + G   S + + S   +  S   
Sbjct: 732 FGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQT 791

Query: 358 DVTSLTEVEECQGLGSGEEGIGAGTSPGHVQDRGGHGVPRAQAPRTEADIGSPEHRPLRQ 417
                      Q  G G+ G G+G S G  Q   G G             G  +H     
Sbjct: 792 SGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSG----------QSSGFGQHESRSH 841

Query: 418 RRTLGAQSTGPSDRGGH 434
           + + G   +G S   G+
Sbjct: 842 QSSYGQHGSGSSQSSGY 858



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 24/97 (24%), Positives = 37/97 (38%)

Query: 298 WGCYGTEQGQTGMGSSDGGGTTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVERASFTE 357
           +G YG+  GQ+      G G+  +S    H   + + + G   S + + S   +  S   
Sbjct: 580 FGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQT 639

Query: 358 DVTSLTEVEECQGLGSGEEGIGAGTSPGHVQDRGGHG 394
                      Q  G G+ G G+G S G  Q   G G
Sbjct: 640 SGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSG 676



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 30/139 (21%), Positives = 50/139 (35%), Gaps = 12/139 (8%)

Query: 298 WGCYGTEQGQTGMGSSDGGGTTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVERASFTE 357
           +G YG+  GQ+        G+  +S    H   +   + G     + + S   +  S + 
Sbjct: 655 FGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSG 714

Query: 358 DVTSLTEVEECQGLGS--GEEGIGAGTSPGHVQDRGGHGVPRAQAPRTEADIGSPEHRPL 415
             +   + E   G  S  G+ G G+G S G  Q   G G             G  +H   
Sbjct: 715 QTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSG----------QSSGFGQHESR 764

Query: 416 RQRRTLGAQSTGPSDRGGH 434
             + + G  S+G S   G+
Sbjct: 765 SGQSSYGQHSSGSSQSSGY 783



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 29/139 (20%), Positives = 48/139 (34%), Gaps = 12/139 (8%)

Query: 298  WGCYGTEQGQTGMGSSDGGGTTGNSLLRSHMKSTPRKTQGPWKSQTERVSSQVERASFTE 357
            +G +G+  GQ+      G G+   S    H   + + + G   S + + S   +  S + 
Sbjct: 884  FGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSG 943

Query: 358  DVTSLTEVEECQGLGSG--EEGIGAGTSPGHVQDRGGHGVPRAQAPRTEADIGSPEHRPL 415
                  +     G  SG  + G G+G S G  Q   G G             G  +H   
Sbjct: 944  QTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSG----------KSSGFGQHESR 993

Query: 416  RQRRTLGAQSTGPSDRGGH 434
              +   G   +G S   G+
Sbjct: 994  SSQSNYGQHGSGSSQSSGY 1012


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 35.0 bits (79), Expect = 0.22
 Identities = 34/125 (27%), Positives = 52/125 (41%), Gaps = 16/125 (12%)

Query: 416  RQRRTLGAQSTGPSDRGGHWRQHVPGT-ITHNTTTTPRELPSSTEATEVRRGV------- 467
            ++ R   AQ T         +    GT +  +  TTP    ++T  ++   G        
Sbjct: 2712 KENRDQSAQCTASKSNDSTEQNLSDGTPMPDSYPTTPSSTDAATSESKETLGTLQSSQQQ 2771

Query: 468  -PCPSSPALGH--QVAQPPPGEGGTAGQLL-PTEP----PHQACRDCFWKLLWVSPVPVL 519
               P+ PALG   Q  Q P GEGG++ QLL P EP    P +   +     + +SP P +
Sbjct: 2772 PTLPTPPALGEVPQELQSPAGEGGSSTQLLMPVEPEELGPTRPSGEAETTQMELSPAPTI 2831

Query: 520  ITPHP 524
             +  P
Sbjct: 2832 TSLSP 2836


>gi|4506321 protein tyrosine phosphatase, receptor type, N precursor
           [Homo sapiens]
          Length = 979

 Score = 35.0 bits (79), Expect = 0.22
 Identities = 27/93 (29%), Positives = 37/93 (39%), Gaps = 32/93 (34%)

Query: 467 VPCPSSPALGHQVAQPPPGEGGTAGQ------------------LLPTEPPHQACRDCFW 508
           +P  S+PA  H++ QPP G+GG                      LLP +PPH +      
Sbjct: 145 IPTGSAPAAQHRLPQPPVGKGGAGASSSLSPLQAELLPPLLEHLLLPPQPPHPS------ 198

Query: 509 KLLWVSPVPVLITPHPL----PRLGVHVSAGRP 537
               +S  P L+ P+       R G  VS G P
Sbjct: 199 ----LSYEPALLQPYLFHQFGSRDGSRVSEGSP 227


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,315,187
Number of Sequences: 37866
Number of extensions: 2015395
Number of successful extensions: 8515
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 215
Number of HSP's that attempted gapping in prelim test: 7918
Number of HSP's gapped (non-prelim): 836
length of query: 663
length of database: 18,247,518
effective HSP length: 109
effective length of query: 554
effective length of database: 14,120,124
effective search space: 7822548696
effective search space used: 7822548696
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.