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Search of human proteins with 239744583
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens]
(1394 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens] 2803 0.0
gi|169204289 PREDICTED: ovostatin [Homo sapiens] 2561 0.0
gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens] 1268 0.0
gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens] 956 0.0
gi|162809334 pregnancy-zone protein [Homo sapiens] 938 0.0
gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens] 714 0.0
gi|239752557 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 462 e-129
gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 392 e-108
gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens] 387 e-107
gi|239752555 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 376 e-104
gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens] 372 e-102
gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens] 364 e-100
gi|169217713 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 278 3e-74
gi|169217831 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 253 7e-67
gi|239755748 PREDICTED: ovostatin [Homo sapiens] 204 5e-52
gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain conta... 181 4e-45
gi|115298678 complement component 3 precursor [Homo sapiens] 171 5e-42
gi|169218213 PREDICTED: similar to complement component C3, part... 157 9e-38
gi|178557739 complement component 4B preproprotein [Homo sapiens] 136 1e-31
gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo s... 135 2e-31
gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo s... 135 2e-31
gi|67190748 complement component 4A preproprotein [Homo sapiens] 135 4e-31
gi|38016947 complement component 5 preproprotein [Homo sapiens] 134 6e-31
gi|239754277 PREDICTED: similar to Complement component 4A (Rodg... 61 9e-09
gi|239758130 PREDICTED: similar to complement component 4B (Chil... 54 1e-06
gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens] 47 1e-04
gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sap... 47 1e-04
gi|169214179 PREDICTED: similar to complement component 3 [Homo ... 32 4.3
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 32 4.3
gi|22550104 ubiquitin specific protease 32 [Homo sapiens] 32 5.6
>gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens]
Length = 1394
Score = 2803 bits (7267), Expect = 0.0
Identities = 1394/1394 (100%), Positives = 1394/1394 (100%)
Query: 1 MTGSHLSHDSWQYVLLIPSVLQEGSLDKACAQLFNLTESVVLTVSLNYGEVQTKIFEENV 60
MTGSHLSHDSWQYVLLIPSVLQEGSLDKACAQLFNLTESVVLTVSLNYGEVQTKIFEENV
Sbjct: 1 MTGSHLSHDSWQYVLLIPSVLQEGSLDKACAQLFNLTESVVLTVSLNYGEVQTKIFEENV 60
Query: 61 TGENFFKCISFEVPQARSDPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYK 120
TGENFFKCISFEVPQARSDPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYK
Sbjct: 61 TGENFFKCISFEVPQARSDPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYK 120
Query: 121 PGQKDVNGIAQFFLDTYTFTYPNITLKDPQNNRIFQWQNVTSFRNITQLSFQLISEPMFG 180
PGQKDVNGIAQFFLDTYTFTYPNITLKDPQNNRIFQWQNVTSFRNITQLSFQLISEPMFG
Sbjct: 121 PGQKDVNGIAQFFLDTYTFTYPNITLKDPQNNRIFQWQNVTSFRNITQLSFQLISEPMFG 180
Query: 181 DYWIVVKRNSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYTFGQPVQ 240
DYWIVVKRNSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYTFGQPVQ
Sbjct: 181 DYWIVVKRNSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYTFGQPVQ 240
Query: 241 GKTQIRVCREYFSSSNCEKNDNEICEQFIAQLENGCVSQIVNTKVFQLYRSGLFMTFHVA 300
GKTQIRVCREYFSSSNCEKNDNEICEQFIAQLENGCVSQIVNTKVFQLYRSGLFMTFHVA
Sbjct: 241 GKTQIRVCREYFSSSNCEKNDNEICEQFIAQLENGCVSQIVNTKVFQLYRSGLFMTFHVA 300
Query: 301 VIVTEFGTGNYCMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFSDPNNVPMV 360
VIVTEFGTGNYCMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFSDPNNVPMV
Sbjct: 301 VIVTEFGTGNYCMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFSDPNNVPMV 360
Query: 361 NKLLQLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPKSCYLPSWLTPQY 420
NKLLQLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPKSCYLPSWLTPQY
Sbjct: 361 NKLLQLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPKSCYLPSWLTPQY 420
Query: 421 LDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLVSL 480
LDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLVSL
Sbjct: 421 LDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLVSL 480
Query: 481 SHDSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQV 540
SHDSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQV
Sbjct: 481 SHDSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQV 540
Query: 541 DKCFKHKVNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYN 600
DKCFKHKVNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYN
Sbjct: 541 DKCFKHKVNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYN 600
Query: 601 MVPSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKV 660
MVPSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKV
Sbjct: 601 MVPSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKV 660
Query: 661 FTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSRIACRGENADYVEQAIIQTVR 720
FTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSRIACRGENADYVEQAIIQTVR
Sbjct: 661 FTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSRIACRGENADYVEQAIIQTVR 720
Query: 721 TNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQPF 780
TNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQPF
Sbjct: 721 TNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQPF 780
Query: 781 FIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSEVIQAG 840
FIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSEVIQAG
Sbjct: 781 FIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSEVIQAG 840
Query: 841 GRKTNIWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEGIEK 900
GRKTNIWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEGIEK
Sbjct: 841 GRKTNIWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEGIEK 900
Query: 901 ERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDILGLAMQNLVVLQMPYGGG 960
ERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDILGLAMQNLVVLQMPYGGG
Sbjct: 901 ERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDILGLAMQNLVVLQMPYGGG 960
Query: 961 EQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQNQ 1020
EQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQNQ
Sbjct: 961 EQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQNQ 1020
Query: 1021 KGSIWLSALTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWEGGD 1080
KGSIWLSALTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWEGGD
Sbjct: 1021 KGSIWLSALTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWEGGD 1080
Query: 1081 EEDISLTAYVVGMFFEAGLNSTFPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKE 1140
EEDISLTAYVVGMFFEAGLNSTFPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKE
Sbjct: 1081 EEDISLTAYVVGMFFEAGLNSTFPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKE 1140
Query: 1141 KQVESLLQTLDQSATKLNNVIYWERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRK 1200
KQVESLLQTLDQSATKLNNVIYWERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRK
Sbjct: 1141 KQVESLLQTLDQSATKLNNVIYWERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRK 1200
Query: 1201 IPDLTYASKIVQWLAQQMNSHGGFSSNQVINVGLILIAICGEEGLFSKNQNTVTFSSEGS 1260
IPDLTYASKIVQWLAQQMNSHGGFSSNQVINVGLILIAICGEEGLFSKNQNTVTFSSEGS
Sbjct: 1201 IPDLTYASKIVQWLAQQMNSHGGFSSNQVINVGLILIAICGEEGLFSKNQNTVTFSSEGS 1260
Query: 1261 SEIQFNGHNRLLVQRSEVTQAPGQYTVDVEGRGCTFIQATLKYNVLLPKKASGFSLSLEI 1320
SEIQFNGHNRLLVQRSEVTQAPGQYTVDVEGRGCTFIQATLKYNVLLPKKASGFSLSLEI
Sbjct: 1261 SEIQFNGHNRLLVQRSEVTQAPGQYTVDVEGRGCTFIQATLKYNVLLPKKASGFSLSLEI 1320
Query: 1321 VKNYSLTVFDLTVNLKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEEVNNRSLIFHHKDSY 1380
VKNYSLTVFDLTVNLKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEEVNNRSLIFHHKDSY
Sbjct: 1321 VKNYSLTVFDLTVNLKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEEVNNRSLIFHHKDSY 1380
Query: 1381 IEYKDKINTCLAVV 1394
IEYKDKINTCLAVV
Sbjct: 1381 IEYKDKINTCLAVV 1394
>gi|169204289 PREDICTED: ovostatin [Homo sapiens]
Length = 1353
Score = 2561 bits (6639), Expect = 0.0
Identities = 1284/1330 (96%), Positives = 1299/1330 (97%), Gaps = 8/1330 (0%)
Query: 73 VPQARSDPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQKDVNGIAQF 132
VPQARSDPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQKDVNGIAQF
Sbjct: 24 VPQARSDPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQKDVNGIAQF 83
Query: 133 FLDTYTFTYPNITLKDPQNNRIFQWQNVTSFRNITQLSFQLISEPMFGDYWIVVKRNSRK 192
FLDTYTFTYPNITLKDPQNNRIFQ QNVTSFRNITQLSFQLISEPMFGDYWIVVKRNSR+
Sbjct: 84 FLDTYTFTYPNITLKDPQNNRIFQRQNVTSFRNITQLSFQLISEPMFGDYWIVVKRNSRE 143
Query: 193 TVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYTFGQPVQGKTQIRVCREYF 252
TVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKY FGQPVQG+TQIRVCREYF
Sbjct: 144 TVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYNFGQPVQGETQIRVCREYF 203
Query: 253 SSSNCEKNDNEICEQFIAQLENGCVSQIVNTKVFQLYRSGLFMTFHVAVIVTEFGTGNYC 312
SSSNCEKN+NEICEQFIAQLENGCVSQIVNTKVFQLYRSGLFMTFHVAVIVTE GTGNY
Sbjct: 204 SSSNCEKNENEICEQFIAQLENGCVSQIVNTKVFQLYRSGLFMTFHVAVIVTESGTGNYF 263
Query: 313 MQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFSDPNNVPMVNKLLQLELNDEF 372
MQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFSDPNNVPMVNKLLQLELNDEF
Sbjct: 264 MQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFSDPNNVPMVNKLLQLELNDEF 323
Query: 373 IGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPKSCYLPSWLTPQYLDAHFLVSRFYS 432
IGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRP+SCYLPSWLTPQYLDAHFLVSRFYS
Sbjct: 324 IGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQYLDAHFLVSRFYS 383
Query: 433 RTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLVSLSHDSGNFQHRIS 492
RTNSFLKIVPEPKQLECN QKVVTVHYSLNSEAYEDDSNVKFFYLVSLSHDSGNFQHRIS
Sbjct: 384 RTNSFLKIVPEPKQLECNQQKVVTVHYSLNSEAYEDDSNVKFFYLVSLSHDSGNFQHRIS 443
Query: 493 SSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVNIKF 552
SSPIYTAWNGNFSFP+SISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVNIKF
Sbjct: 444 SSPIYTAWNGNFSFPISISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVNIKF 503
Query: 553 SNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYNMVPSIEPYGYFY 612
SNEQGLPGSNASL LQAAPVLFCAL AVD NVLLLKSEQQLSAESVYNMVPSIEPYGYFY
Sbjct: 504 SNEQGLPGSNASLCLQAAPVLFCALRAVDRNVLLLKSEQQLSAESVYNMVPSIEPYGYFY 563
Query: 613 HGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVC 672
HGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVC
Sbjct: 564 HGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVC 623
Query: 673 VMERRLPLPKPLYLETENYGPMHSVPSRIACRGENADYVEQAIIQTVRTNFPETWMWDLV 732
VMERRLPLPKPLYLETENYGPM SVPSRIACRGENADYVEQAIIQTVRTNFPETWMWDLV
Sbjct: 624 VMERRLPLPKPLYLETENYGPMRSVPSRIACRGENADYVEQAIIQTVRTNFPETWMWDLV 683
Query: 733 SVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQPFFIEIASPFSVVQ 792
SVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQPFFIEIASPFSVVQ
Sbjct: 684 SVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQPFFIEIASPFSVVQ 743
Query: 793 NEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSEVIQAGGRKTNIWTIIPK 852
NEQFDLIVN FSY NTCVEISVQVEESQNYEANI+T KINGSEVIQAGGRKTN+WTIIPK
Sbjct: 744 NEQFDLIVNVFSYRNTCVEISVQVEESQNYEANIHTLKINGSEVIQAGGRKTNVWTIIPK 803
Query: 853 KLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEGIEKERTQSFLICTEG 912
KLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVV+SFLVEPEGIEKERTQSFLICTEG
Sbjct: 804 KLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVQSFLVEPEGIEKERTQSFLICTEG 863
Query: 913 AKASKQGVLDLPNDVVEGSARGFFTVVGDILGLAMQNLVVLQMPYGGGEQNAALLASDTY 972
AKASKQGVLDLPNDVVEGSARGFFTVVGDILGLA+QNLVVLQMPYG GEQNAALLASDTY
Sbjct: 864 AKASKQGVLDLPNDVVEGSARGFFTVVGDILGLALQNLVVLQMPYGSGEQNAALLASDTY 923
Query: 973 VLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQNQKGSIWLSALTFK 1032
VLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQ+QKGSI LSALTFK
Sbjct: 924 VLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQSQKGSIXLSALTFK 983
Query: 1033 TLERMKKFVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWEGGDEEDISLTAYVVG 1092
TLERMKK+VFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWEGGDEEDISLTAYVVG
Sbjct: 984 TLERMKKYVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWEGGDEEDISLTAYVVG 1043
Query: 1093 MFFEAGLNSTFPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQ 1152
MFFEAGLN TFPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQ
Sbjct: 1044 MFFEAGLNFTFPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQ 1103
Query: 1153 SATKLNNVIYWERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIVQ 1212
SA KLNNVIYWERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIVQ
Sbjct: 1104 SAPKLNNVIYWERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIVQ 1163
Query: 1213 WLAQQMNSHGGFSSNQVINVGLILIAIC-------GEEGLFSKNQNTVTFSSEGSSEI-Q 1264
WLAQ+MNSHGGFSSNQVINVGLILIAIC GEEGLFSK+QNTVTFSSEGSSEI Q
Sbjct: 1164 WLAQRMNSHGGFSSNQVINVGLILIAICLMQKLARGEEGLFSKDQNTVTFSSEGSSEIFQ 1223
Query: 1265 FNGHNRLLVQRSEVTQAPGQYTVDVEGRGCTFIQATLKYNVLLPKKASGFSLSLEIVKNY 1324
NGHNRLLVQRSEVTQAPG+YTVDVEG GCTFIQATLKYNVLLPKKASGFSLSLEIVKNY
Sbjct: 1224 VNGHNRLLVQRSEVTQAPGEYTVDVEGHGCTFIQATLKYNVLLPKKASGFSLSLEIVKNY 1283
Query: 1325 SLTVFDLTVNLKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEEVNNRSLIFHHKDSYIEYK 1384
S T FDLTV LKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEEVNNRSLIF HKDSYIEYK
Sbjct: 1284 SSTAFDLTVTLKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEEVNNRSLIFQHKDSYIEYK 1343
Query: 1385 DKINTCLAVV 1394
DKINTC A+V
Sbjct: 1344 DKINTCSAIV 1353
>gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens]
Length = 750
Score = 1268 bits (3281), Expect = 0.0
Identities = 632/642 (98%), Positives = 634/642 (98%), Gaps = 5/642 (0%)
Query: 359 MVNKLLQLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPKSCYLPSWLTP 418
MVNKLLQLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRP+SCYLPSWLTP
Sbjct: 1 MVNKLLQLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTP 60
Query: 419 QYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLV 478
QYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYL
Sbjct: 61 QYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLC 120
Query: 479 SLSHDSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRF 538
+ DSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRF
Sbjct: 121 T--SDSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRF 178
Query: 539 QVDKCFKHKVNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESV 598
QVDKCFKHKVNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESV
Sbjct: 179 QVDKCFKHKVNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESV 238
Query: 599 YNMVPSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGL 658
YNMVPSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGL
Sbjct: 239 YNMVPSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGL 298
Query: 659 KVFTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSRIAC---RGENADYVEQAI 715
KVFTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSRIA RGENADYVEQAI
Sbjct: 299 KVFTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSRIASSGIRGENADYVEQAI 358
Query: 716 IQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLE 775
IQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLE
Sbjct: 359 IQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLE 418
Query: 776 VSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSE 835
VSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSE
Sbjct: 419 VSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSE 478
Query: 836 VIQAGGRKTNIWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEP 895
VIQAGGRKTNIWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEP
Sbjct: 479 VIQAGGRKTNIWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEP 538
Query: 896 EGIEKERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDILGLAMQNLVVLQM 955
EGIEKERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDILGLAMQNLVVLQM
Sbjct: 539 EGIEKERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDILGLAMQNLVVLQM 598
Query: 956 PYGGGEQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSN 997
PYGGGEQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSN
Sbjct: 599 PYGGGEQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSN 640
Score = 40.0 bits (92), Expect = 0.016
Identities = 18/32 (56%), Positives = 23/32 (71%)
Query: 175 SEPMFGDYWIVVKRNSRKTVTHQFAVKRYVLP 206
+E +FG Y IVVKR S KT+THQF +K +P
Sbjct: 702 NETVFGGYSIVVKRKSGKTLTHQFTIKAIPVP 733
>gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens]
Length = 1474
Score = 956 bits (2471), Expect = 0.0
Identities = 538/1413 (38%), Positives = 829/1413 (58%), Gaps = 55/1413 (3%)
Query: 12 QYVLLIPSVLQEGSLDKACAQLFNLTESVVLTVSLNYGEVQTKIFEENVTGENFFKCISF 71
QY++L+PS+L + +K C L L E+V ++ SL +F + + C++F
Sbjct: 30 QYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVRGNRSLFTDLEAENDVLHCVAF 89
Query: 72 EVPQARS-DPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQKDVNGIA 130
VP++ S + + F+T KG T ++R +V +++ +++VFVQTDK YKPGQ +
Sbjct: 90 AVPKSSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVV 149
Query: 131 QFFLDTYTFT--YPNITLKDPQNNRIFQWQNVTSFRNITQLSFQLISEPMFGDYWIVVKR 188
+ + P + ++DP+ NRI QWQ+ + Q SF L SEP G Y +VV++
Sbjct: 150 SMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQK 209
Query: 189 NSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYTFGQPVQGKTQIRVC 248
S H F V+ +VLPKFEV V P+ +TI ++E V VC YT+G+PV G + +C
Sbjct: 210 KSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSIC 269
Query: 249 REYFSSSNCEKNDNE-ICEQFIAQLEN-GCVSQIVNTKVFQLYRSGLFMTFHVAVIVTEF 306
R+Y +S+C D++ CE+F QL + GC Q V TKVFQL R M H + E
Sbjct: 270 RKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEE 329
Query: 307 GTGNYCMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFSDPNNVPMVNKLLQL 366
GT ++++ + S IT+ + ++F +D+ +R+GI +FG ++ D VP+ NK++ +
Sbjct: 330 GT---VVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFI 386
Query: 367 ELND-EFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPKSCYLPSWLTPQYLDAHF 425
N+ + N TTDE+G QFSI+T+++ ++ Y CY W++ ++ +AH
Sbjct: 387 RGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHH 446
Query: 426 LVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLVSLSHD-- 483
+S + SF+ + P +L C H + V HY LN + F+YL+
Sbjct: 447 TAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIV 506
Query: 484 -SGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDK 542
+G + + G+FS + + +D+AP A L +Y + P+G+++ DS ++ V+
Sbjct: 507 RTGTHGLLVKQEDM----KGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVEN 562
Query: 543 CFKHKVNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYNMV 602
C +KV++ FS Q LP S+A L + AAP CAL AVD +VLL+K + +LSA SVYN++
Sbjct: 563 CLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLL 622
Query: 603 PSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFT 662
P + G+ L+D ++ CI + +++ NG+ YTPVS+ + D+Y+ + +MGLK FT
Sbjct: 623 PEKDLTGF---PGPLNDQDDEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFT 679
Query: 663 NLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSRIACRGE-NADYVEQAIIQTVRT 721
N RKP++C ++ + P L Y S + RG +VE+ +TVR
Sbjct: 680 NSKIRKPKMCPQLQQYEMHGPEGLRVGFY------ESDVMGRGHARLVHVEEPHTETVRK 733
Query: 722 NFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQPFF 781
FPETW+WDLV V+S+G A + +PDTIT+W+A FC++ D G GISST +L QPFF
Sbjct: 734 YFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFF 793
Query: 782 IEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSEVIQAGG 841
+E+ P+SV++ E F L +YL C+ +SVQ+E S + A + K I A G
Sbjct: 794 VELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLA-VPVEKEQAPHCICANG 852
Query: 842 RKTNIWTIIPKKLGKVNITVVAESKQS-SACPNEGMEQQKLNWKDTVVKSFLVEPEGIEK 900
R+T W + PK LG VN TV AE+ +S C E + KDTV+K LVEPEG+EK
Sbjct: 853 RQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEK 912
Query: 901 ERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDILGLAMQNLV-VLQMPYGG 959
E T + L+C G + S++ L LP +VVE SAR +V+GDILG AMQN +LQMPYG
Sbjct: 913 ETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGC 972
Query: 960 GEQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQ- 1018
GEQN L A + YVLDYL T+QLT E++SKA L+ GYQRQL++K+ DGSYS F ++
Sbjct: 973 GEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERY 1032
Query: 1019 -NQKGSIWLSALTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWE 1077
+G+ WL+A KT + + ++FIDE Q LIWLS +QK +GCF++ G L N+A +
Sbjct: 1033 GRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIK 1092
Query: 1078 GGDEEDISLTAYVVGMFFEAGLNSTFPALRNALFCLEAAL------DSGVTNGYNHAILA 1131
GG E++++L+AY+ E L T P +RNALFCLE+A D G ++ Y A+LA
Sbjct: 1093 GGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHG-SHVYTKALLA 1151
Query: 1132 YAFALAGKEKQVESLLQTLDQSATKLNNVIYWERERKPKTEEFPSFIPWAPSAQTEKSCY 1191
YAFALAG + + + +L++L++ A K +N ++WER +KPK + P APSA+ E + Y
Sbjct: 1152 YAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSY 1211
Query: 1192 VLLAVISRK----IPDLTYASKIVQWLAQQMNSHGGFSSNQVINVGLILIAICGEEGLFS 1247
VLLA ++ + DLT A+ IV+W+ +Q N+ GGFSS Q V L ++ G F+
Sbjct: 1212 VLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYG-AATFT 1270
Query: 1248 KN----QNTVTFSSEGSSEIQFNGHNRLLVQRSEVTQAPGQYTVDVEGRGCTFIQATLKY 1303
+ Q T+ S SS+ Q + +NRLL+Q+ + + PG+Y++ V G GC ++Q +LKY
Sbjct: 1271 RTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKY 1330
Query: 1304 NVLLPKKASGFSLSLEIV-----KNYSLTVFDLTVNLKYTGIRNKSSMVVIDVKMLSGF- 1357
N+L K+ F+L ++ + + + T F +++++ YTG R+ S+M ++DVKM+SGF
Sbjct: 1331 NILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFI 1390
Query: 1358 --TPTMSSIEEVNNRSLIFHHKDSYIEYKDKIN 1388
PT+ +E N+ S + + Y DK++
Sbjct: 1391 PLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVS 1423
>gi|162809334 pregnancy-zone protein [Homo sapiens]
Length = 1482
Score = 938 bits (2424), Expect = 0.0
Identities = 538/1401 (38%), Positives = 827/1401 (59%), Gaps = 57/1401 (4%)
Query: 12 QYVLLIPSVLQEGSLDKACAQLFNLTESVVLTVSLNYGEVQTKIFEENVTGENFFKCISF 71
QY++L+PS+L + K C L +L E+V ++ SL G +F + V ++ F C+SF
Sbjct: 29 QYMVLVPSLLHTEAPKKGCVLLSHLNETVTVSASLESGRENRSLFTDLVAEKDLFHCVSF 88
Query: 72 EVPQ-ARSDPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQK---DVN 127
+P+ + S +AF++ KG T + +R +V + + +++VFVQTDKP YKPGQ V
Sbjct: 89 TLPRISASSEVAFLSIQIKGPTQDFRKRNTVLVLNTQSLVFVQTDKPMYKPGQTVRFRVV 148
Query: 128 GIAQFFLDTYTFTYPNITLKDPQNNRIFQWQNVTSFRNITQLSFQLISEPMFGDYWIVVK 187
+ + F P I L++P+ NRI QWQ++ I QLSF L SEP+ G Y +VV+
Sbjct: 149 SVDENFRPRNELI-PLIYLENPRRNRIAQWQSLKLEAGINQLSFPLSSEPIQGSYRVVVQ 207
Query: 188 RNSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYTFGQPVQGKTQIRV 247
S + H F V+ +VLPKFEV V P+ ++I D++ + VC +YT+G+PV G + +
Sbjct: 208 TESGGRIQHPFTVEEFVLPKFEVKVQVPKIISIMDEKVNITVCGEYTYGKPVPGLATVSL 267
Query: 248 CREYFSSSNCEKNDNEICEQFIAQLE-NGCVSQIVNTKVFQLYRSGLFMTFHVAVIVTEF 306
CR+ NC+K E+CE+F QL NGC++Q V+TK+ Q+ +G M V + E
Sbjct: 268 CRKLSRVLNCDKQ--EVCEEFSQQLNSNGCITQQVHTKMLQITNTGFEMKLRVEARIREE 325
Query: 307 GTGNYCMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFSDPNNVPMVNKLLQL 366
GT ++++ IT ++ + F +D+ +R+GI +F + D VP+ NKL +
Sbjct: 326 GTD---LEVTANRISEITNIVSKLKFVKVDSHFRQGIPFFAQVLLVDGKGVPIPNKLFFI 382
Query: 367 ELND-EFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPKSCYLPSWLTPQYLDAHF 425
+ND + N TT+E G AQFSI+T+ I + ++ V P C+ SW+ + A
Sbjct: 383 SVNDANYYSNATTNEQGLAQFSINTTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQH 442
Query: 426 LVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLVSLSH--- 482
+R +S + S++ + P L C H + +T HY+LN +A + S + F YL+
Sbjct: 443 TANRVFSLSGSYIHLEPVAGTLPCGHTETITAHYTLNRQAMGELSELSFHYLIMAKGVIV 502
Query: 483 DSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDK 542
SG + S + G+F+ + +D+AP A +F++ + P GE+V DS +F+++
Sbjct: 503 RSGTHTLPVESGDM----KGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEIEN 558
Query: 543 CFKHKVNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYNMV 602
C +KV++ FS Q P S+A L + AAP CAL AVD +VLL+K E +LS SVYN++
Sbjct: 559 CLANKVDLSFSPAQSPPASHAHLQVAAAPQSLCALRAVDQSVLLMKPEAELSVSSVYNLL 618
Query: 603 PSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFT 662
+++ F ++ + ++ C P+ +NG Y P+S+ + DIY+ ++ MGLKVFT
Sbjct: 619 -TVKDLTNFPDNVDQQEEEQGHC-PRPFFIHNGAIYVPLSS-NEADIYSFLKGMGLKVFT 675
Query: 663 NLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSR--IACRGE------NADYVEQA 714
N RKP+ C + +P + YG V R + G N +
Sbjct: 676 NSKIRKPKSCSV---IPSVSAGAVGQGYYGAGLGVVERPYVPQLGTYNVIPLNNEQSSGP 732
Query: 715 IIQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTL 774
+ +TVR+ FPETW+W+LV+V+SSG A + +PDTIT+W+A FC++ D G GISST +L
Sbjct: 733 VPETVRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASL 792
Query: 775 EVSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGS 834
QPFF+E+ P+SV++ E F L +YL C+ +SVQ++ S + A+ NT K S
Sbjct: 793 RAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLASQNT-KGEES 851
Query: 835 EVIQAGGRKTNIWTIIPKKLGKVNITVVAESKQS-SACPNEGMEQQKLNWKDTVVKSFLV 893
I R+T WT+ PK LG VN +V AE+ QS C NE +E ++ KDTV+K+ LV
Sbjct: 852 YCICGNERQTLSWTVTPKTLGNVNFSVSAEAMQSLELCGNEVVEVPEIKRKDTVIKTLLV 911
Query: 894 EPEGIEKERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDILGLAMQNLV-V 952
E EGIE+E+T S + C GA S+Q L LP++VV+ SAR F+V+GDILG AMQN+ +
Sbjct: 912 EAEGIEQEKTFSSMTCASGANVSEQLSLKLPSNVVKESARASFSVLGDILGSAMQNIQNL 971
Query: 953 LQMPYGGGEQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSY 1012
LQMPYG GEQN L A + YVL+YL T+QLT+E+++KA L GYQRQL++K+ DGSY
Sbjct: 972 LQMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQEIKAKAVGYLITGYQRQLNYKHQDGSY 1031
Query: 1013 SVFWQQ--NQKGSIWLSALTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSGCFKNDGQ 1070
S F ++ +G+ WL+A KT + + ++FIDE Q+L WLS QK +GCF++ G
Sbjct: 1032 STFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQKDNGCFRSSGS 1091
Query: 1071 LFNHAWEGGDEEDISLTAYVVGMFFEAGLNSTFPALRNALFCLEAALDSGV--TNG---Y 1125
L N+A +GG E++ +L+AYV E L T P +RNALFCLE+A + T+G Y
Sbjct: 1092 LLNNAIKGGVEDEATLSAYVTIALLEIPLPVTNPIVRNALFCLESAWNVAKEGTHGSHVY 1151
Query: 1126 NHAILAYAFALAGKEKQVESLLQTLDQSATKLNNVIYWERERKPKTEEFPSFIPWAPSAQ 1185
A+LAYAF+L GK+ Q +L +LD+ A K +N+++WER ++PK + APSA+
Sbjct: 1152 TKALLAYAFSLLGKQNQNREILNSLDKEAVKEDNLVHWERPQRPKAPVGHLYQTQAPSAE 1211
Query: 1186 TEKSCYVLLAVISRK----IPDLTYASKIVQWLAQQMNSHGGFSSNQVINVGLILIAICG 1241
E + YVLLA ++ + DLT A+ IV+W+ +Q N+ GGFSS Q V L ++ G
Sbjct: 1212 VEMTSYVLLAYLTAQPAPTSGDLTSATNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYG 1271
Query: 1242 EEGLFSKN----QNTVTFSSEGSSEIQFNGHNRLLVQRSEVTQAPGQYTVDVEGRGCTFI 1297
F++ Q TV S S+ Q + +N LL+Q+ + + PG+Y + V G C ++
Sbjct: 1272 -AATFTRTEKTAQVTVQDSQTFSTNFQVDNNNLLLLQQISLPELPGEYVITVTGERCVYL 1330
Query: 1298 QATLKYNVLLPKKASGFSLSLEIVK-----NYSLTVFDLTVNLKYTGIRNKSSMVVIDVK 1352
Q ++KYN+L K+ S F+L ++ V + + T F +++ + YTG R S+MV++DVK
Sbjct: 1331 QTSMKYNILPEKEDSPFALKVQTVPQTCDGHKAHTSFQISLTISYTGNRPASNMVIVDVK 1390
Query: 1353 MLSGFTPTMSSIEEVNNRSLI 1373
M+SGF P +++ + S +
Sbjct: 1391 MVSGFIPLKPTVKMLERSSSV 1411
>gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]
Length = 1454
Score = 714 bits (1842), Expect = 0.0
Identities = 465/1390 (33%), Positives = 710/1390 (51%), Gaps = 78/1390 (5%)
Query: 13 YVLLIPSVLQEGSLDKACAQLFNLTESVVLTVSLNYGEVQTKIFEENVTGENFFKCISFE 72
Y++ +P+ L S+ K C L V TV+L + K+ E + + CISF
Sbjct: 23 YLVTLPARLNFPSVQKVCLDLSPGYSDVKFTVTLETKDKTQKLLEYSGLKKRHLHCISFL 82
Query: 73 VPQAR--SDPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQKDVNGIA 130
VP ++ +A I S G ++ EE++ V I+ + N FVQTDKP Y PGQ+ I
Sbjct: 83 VPPPAGGTEEVATIRVSGVGNNISFEEKKKVLIQRQGNGTFVQTDKPLYTPGQQVYFRIV 142
Query: 131 QFFLDTYTFT--YPNITLKDPQNNRIFQWQNVTSFRNITQLSFQLISEPMFGDYWIVVKR 188
+ Y + L+DP +NRI QW V + I LSFQL E M G Y + V
Sbjct: 143 TMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVDLSFQLAPEAMLGTYTVAVAE 202
Query: 189 NSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYTFGQPVQGKTQIRVC 248
F+V+ YVLPKF+V V P+ ++ + F V +C +YT+G+P+ G Q+ VC
Sbjct: 203 GK---TFGTFSVEEYVLPKFKVEVVEPKELSTVQESFLVKICCRYTYGKPMLGAVQVSVC 259
Query: 249 RE---YFSSSNCEKNDNEICEQFIAQLEN-GCVSQIVNTKVFQLYRSGLFMTFHVAVIVT 304
++ Y+ + + C Q + GC S V+ F L ++ V
Sbjct: 260 QKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPVDMATFDLIGYAYSHQINIVATVV 319
Query: 305 EFGTGNYCMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFSDPNNVPMVNKLL 364
E GTG ++ + +++I+ +G++ FE+ FY + G ++ ++ + N L+
Sbjct: 320 EEGTG---VEANATQNIYISPQMGSMTFEDTSNFYHPNFPFSGKIRVRGHDDSFLKNHLV 376
Query: 365 QLEL---NDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPKSCYLPSWLTPQYL 421
L + N F TD NG A F+++TS + +L+ + Y P + Y
Sbjct: 377 FLVIYGTNGTFNQTLVTDNNGLAPFTLETSGWNGTDVSLEGKFQMEDLVYNPEQVPRYYQ 436
Query: 422 DAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKF-FYLVSL 480
+A+ + FYS T SFL I L+C + V V Y ++ D + F +YL+
Sbjct: 437 NAYLHLRPFYSTTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPADASPDQEISFSYYLIGK 496
Query: 481 SHDSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQV 540
Q ++S +FS L+ ++ LAP L +Y + PSG +VAD ++F V
Sbjct: 497 GSLVMEGQKHLNSKK--KGLKASFSLSLTFTSRLAPDPSLVIYAIFPSGGVVADKIQFSV 554
Query: 541 DKCFKHKVNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYN 600
+ CF ++V++ FS Q LPG+ L LQAAP CAL AVD +VLLL+ +++LS SVY
Sbjct: 555 EMCFDNQVSLGFSPSQQLPGAEVELQLQAAPGSLCALRAVDESVLLLRPDRELSNRSVYG 614
Query: 601 MVPSIEPYGYFYHGLNLDDGKEDPC---------------IPQRDMFYNGLYYTPVSNYG 645
M P YG++ + + + D C +PQ + + P + G
Sbjct: 615 MFPFW--YGHYPYQV----AEYDQCPVSGPWDFPQPLIDPMPQGHSSQRSIIWRPSFSEG 668
Query: 646 DGDIYNIVRNMGLKVFTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSRIACRG 705
D+++ R++GLK+ +N +KP C P Y G H P
Sbjct: 669 T-DLFSFFRDVGLKILSNAKIKKPVDCSHR------SPEYSTAMGAGGGH--PEAF---- 715
Query: 706 ENADYVEQAIIQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVG 765
E++ + QA VR FPETW+WDL + +SG + +PD IT+W+A FC + G
Sbjct: 716 ESSTPLHQAEDSQVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRG 775
Query: 766 FGISSTTTLEVSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEAN 825
FG+S T L +PFF+++ P+SVV+ E F L F+YL C+ + + +S Y+
Sbjct: 776 FGLSPTVGLTAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKSHEYQ-- 833
Query: 826 INTWKING-SEVIQAGGRKTNIWTIIPKKLGKVNITVVAESKQSSA-CPNE-GMEQQKLN 882
+ +W + S + A KT+ W I KLG +N T+ + S+ C + G QK
Sbjct: 834 LESWADSQTSSCLCADEAKTHHWNITAVKLGHINFTISTKILDSNEPCGGQKGFVPQK-G 892
Query: 883 WKDTVVKSFLVEPEGIEKERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDI 942
DT++K LV+PEG+ E+T S L+C +G AS+ L+LP D+V S + + TV+GDI
Sbjct: 893 RSDTLIKPVLVKPEGVLVEKTHSSLLCPKGKVASESVSLELPVDIVPDSTKAYVTVLGDI 952
Query: 943 LGLAMQNLV-VLQMPYGGGEQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQR 1001
+G A+QNL ++QMP G GEQN L A YVL YL+ LTEE++S+A L GYQ+
Sbjct: 953 MGTALQNLDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKAGLLTEEIRSRAVGFLEIGYQK 1012
Query: 1002 QLSFKNSDGSYSVFWQQNQKGSIWLSALTFKTLERMKKFVFIDENVQKQTLIWLSSQQKT 1061
+L +K+S+GSYS F +++ G+ WL+A K + +KF+FID + L W++ Q
Sbjct: 1013 ELMYKHSNGSYSAFGERDGNGNTWLTAFVTKCFGQAQKFIFIDPKNIQDALKWMAGNQLP 1072
Query: 1062 SGCFKNDGQLFNHAWEGGDEEDISLTAYVVGMFFEAGLNSTFPALRNALFCLEAALDSGV 1121
SGC+ N G L + A +GG ++++SLTAYV E G + P + L CL+ + S
Sbjct: 1073 SGCYANVGNLLHTAMKGGVDDEVSLTAYVTAALLEMGKDVDDPMVSQGLRCLKNSATS-T 1131
Query: 1122 TNGYNHAILAYAFALAGKEKQVESLLQTLDQSATKLNNVIYWERERKPKTEEFPSFIPWA 1181
TN Y A+LAY F+LAG+ LL+ LDQ A IYW ++ P + P P A
Sbjct: 1132 TNLYTQALLAYIFSLAGEMDIRNILLKQLDQQAIISGESIYWSQKPTPSSNASPWSEPAA 1191
Query: 1182 PSAQTEKSCYVLLAVISRKIPDLTY-----ASKIVQWLAQQMNSHGGFSSNQVINVGLIL 1236
E + Y LLA +++ P LT A+ IV WLA+Q N++GGFSS Q V L
Sbjct: 1192 --VDVELTAYALLAQLTK--PSLTQKEIAKATSIVAWLAKQRNAYGGFSSTQDTVVALQA 1247
Query: 1237 IAICGEEGLFSKNQNTVTFSSEGSSEIQFN--GHNRLLVQRSEVTQAPGQYTVDVEGRGC 1294
+A + + S + + FN NRL+ Q+ + PG YT++ G+GC
Sbjct: 1248 LAKYATTAYMPSEEINLVVKSTENFQRTFNIQSVNRLVFQQDTLPNVPGMYTLEASGQGC 1307
Query: 1295 TFIQATLKYNVLLPKKASGFSLSLEIVK-----NYSLTVFDLTVNLKYTGIRNKSSMVVI 1349
++Q L+YN+L P FSLS+EI K S LT++ Y G R+ S+M ++
Sbjct: 1308 VYVQTVLRYNILPPTNMKTFSLSVEIGKARCEQPTSPRSLTLTIHTSYVGSRSSSNMAIV 1367
Query: 1350 DVKMLSGFTP 1359
+VKMLSGF+P
Sbjct: 1368 EVKMLSGFSP 1377
>gi|239752557 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 261
Score = 462 bits (1189), Expect = e-129
Identities = 232/246 (94%), Positives = 236/246 (95%), Gaps = 2/246 (0%)
Query: 359 MVNKLLQLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPKSCYLPSWLTP 418
MVNKLLQLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRP+SCYLPSWLTP
Sbjct: 1 MVNKLLQLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTP 60
Query: 419 QYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLV 478
QYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYL
Sbjct: 61 QYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYL- 119
Query: 479 SLSHDSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRF 538
+ DSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRF
Sbjct: 120 -CTSDSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRF 178
Query: 539 QVDKCFKHKVNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESV 598
QVDKCFKHKVNIKFSNEQGLPGSNASL LQAAPVLFCAL AVD NVLLLKSEQQLSAESV
Sbjct: 179 QVDKCFKHKVNIKFSNEQGLPGSNASLCLQAAPVLFCALRAVDRNVLLLKSEQQLSAESV 238
Query: 599 YNMVPS 604
++ S
Sbjct: 239 SSLTSS 244
>gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 278
Score = 392 bits (1007), Expect = e-108
Identities = 195/202 (96%), Positives = 195/202 (96%), Gaps = 3/202 (1%)
Query: 656 MGLKVFTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSRIAC---RGENADYVE 712
MGLKVFTNLHYRKPEVCVMERRLPLPKPLYLETENYGPM SVPSRIA RGENADYVE
Sbjct: 1 MGLKVFTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMRSVPSRIASSGIRGENADYVE 60
Query: 713 QAIIQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTT 772
QAIIQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTT
Sbjct: 61 QAIIQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTT 120
Query: 773 TLEVSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKIN 832
TLEVSQPFFIEIASPFSVVQNEQFDLIVN FSY NTCVEISVQVEESQNYEANINTWKIN
Sbjct: 121 TLEVSQPFFIEIASPFSVVQNEQFDLIVNVFSYRNTCVEISVQVEESQNYEANINTWKIN 180
Query: 833 GSEVIQAGGRKTNIWTIIPKKL 854
GSEVIQAGGRKTNIWTIIPKKL
Sbjct: 181 GSEVIQAGGRKTNIWTIIPKKL 202
>gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]
Length = 1445
Score = 387 bits (993), Expect = e-107
Identities = 360/1344 (26%), Positives = 594/1344 (44%), Gaps = 184/1344 (13%)
Query: 110 VFVQTDKPTYKPGQKDVNGIAQFFLDTYTF-TYPNITLKDPQNNRIFQWQNVTSFRNITQ 168
VF+QTDK YKP Q+ I F D + T NI +KDP++N I QW + S +
Sbjct: 131 VFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVIS 190
Query: 169 LSFQLISEPMFGDYWIVVKRNSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVD 228
+FQL S P+ GD+ I V+ N + T F V YVLPKFEVT+ P +++
Sbjct: 191 KTFQLSSHPILGDWSIQVQVNDQ-TYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGT 249
Query: 229 VCAKYTFGQPVQG--------------KTQIRVCREYFSSSNCEKNDNEICEQFIAQLEN 274
+ AKYT+G+PV+G K I + S+N ND E+ + + N
Sbjct: 250 ITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEM--KNVMDSSN 307
Query: 275 GCVSQIVNTKVFQLYRSGLFMTFHVAVIVTEFGTGNYCMQISEKTSVFITQLLGTVNFEN 334
G ++ L G + VTE TG + + T+VF Q + F +
Sbjct: 308 GL------SEYLDLSSPG---PVEILTTVTESVTG---ISRNVSTNVFFKQHDYIIEFFD 355
Query: 335 MDTFYRRGISYFGTLKFS--DPNNVPMVNK-------LLQLELNDEFIGNYTTDENGEA- 384
T + +++ T+K + D N + + + + Q + + G+ + ++ EA
Sbjct: 356 YTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAV 415
Query: 385 ---QFSIDTSDIFDPEFNL--KATYVRPKSCYLPSWLTPQYLDAHFLVSRFYSRTNSFLK 439
+++ S F EF + ++ ++ K+ +L S + H L + S+T LK
Sbjct: 416 QKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGS---KSSMAVHSLF-KSPSKTYIQLK 471
Query: 440 IVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLVSLSHDSGNFQHRISSSPIYTA 499
E ++ + VV+ + L +Y S + LV++ +
Sbjct: 472 TRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQ---LVAVGKQNSTM------------ 516
Query: 500 WNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVNIKFSNEQGLP 559
F L+ P A + VY + GEI++D ++ V FK+K+ + +S + P
Sbjct: 517 ------FSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEP 570
Query: 560 GSNASLYLQAA-PVLFCALGAVDGNVLLLKSEQQLSAESVYNMVPSIEPYGYFYHGLNLD 618
SL + P + AVD +V L+ + ++ E N+V +E Y Y+
Sbjct: 571 SEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITME---NVVHELELYNTGYY----- 622
Query: 619 DGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVCVMERRL 678
MF N + + + GL V T+ + K + +
Sbjct: 623 ----------LGMFMNS--------------FAVFQECGLWVLTDANLTKDYIDGVYDNA 658
Query: 679 PLPKPLYLETENYGPMHSVPSRIACRGENADYVEQAIIQTVRTNFPETWMWDLVSVDSSG 738
+ E E H V G + VR +FPETW+W ++
Sbjct: 659 EYAERFMEENEG----HIVDIHDFSLGSSPH---------VRKHFPETWIWLDTNMGYRI 705
Query: 739 SANLSFLIPDTITQWEASGFCVNGDVGFGISSTTT-LEVSQPFFIEIASPFSVVQNEQFD 797
+PD+IT W A+GF ++ D+G G+++T L+ QPFFI + P+SV++ E+F
Sbjct: 706 YQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFA 765
Query: 798 LIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSE-----VIQAGGRKTNIWTIIPK 852
L + F+YL E+ V +E+S ++ + + +IN + ++ + T ++ I P
Sbjct: 766 LEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPT 825
Query: 853 KLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEGIEKERTQSFLI-CTE 911
LG++ ITV A S +S D V + LV+ EGIEK +QS L+ T+
Sbjct: 826 HLGEIPITVTALSPTAS---------------DAVTQMILVKAEGIEKSYSQSILLDLTD 870
Query: 912 GAKASKQGVLDL--PNDVVEGSARGFFTVVGDILGLAMQNLV-VLQMPYGGGEQNAALLA 968
S L P + V GS R T +GD+LG ++ L +++MPYG GEQN A
Sbjct: 871 NRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFA 930
Query: 969 SDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQNQKGSIWLSA 1028
+ Y+LDYL +QLT+ ++ KA + GYQR+L ++ DGS+S F + GS WLSA
Sbjct: 931 PNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSA 990
Query: 1029 LTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWEGGDEEDISLTA 1088
+ ++ ID+NV +T WL QK++G F + G++ + +GG++ ++LTA
Sbjct: 991 FVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTA 1050
Query: 1089 YVVGMFFEAGLNSTFPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQ 1148
Y+V ++ ++ LE+ G+++ Y A++ YA + G K E+ L
Sbjct: 1051 YIVTSLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEA-LN 1109
Query: 1149 TLDQSATKLNNVIYWERERKPKTEEFPSFIPWAP-SAQTEKSCYVLLA-----VISRKIP 1202
L A + + +W ++ W P S E + Y LL+ S IP
Sbjct: 1110 MLTWRAEQEGGMQFWVSSESKLSDS------WQPRSLDIEVAAYALLSHFLQFQTSEGIP 1163
Query: 1203 DLTYASKIVQWLAQQMNSHGGFSSNQVINVGLILIAICGEEGLFSKNQNTVTFSSEGS-S 1261
I++WL++Q NS GGF+S Q V L ++ + VT + S S
Sbjct: 1164 -------IMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPS 1216
Query: 1262 EIQF--NGHNRLLVQRSEVTQA-PGQYTVDVEGRGCTFIQATLKYNVLLPKKASG----- 1313
++F + HNRLL+Q +E+ P + G G Q + YNV KASG
Sbjct: 1217 PVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNV----KASGSSRRR 1272
Query: 1314 --------FSLSLEIVKNY-SLTVFDLTVNLKYTGIRNKSSMVVIDVKMLSGFTPTMSSI 1364
F L + + +N L DL V ++G +S M +++V +LSGF +I
Sbjct: 1273 RSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFSG-PGRSGMALMEVNLLSGFMVPSEAI 1331
Query: 1365 EEVNNRSLIFHHKDSYIEYKDKIN 1388
+ + Y D +N
Sbjct: 1332 SLSETVKKVEYDHGKLNLYLDSVN 1355
>gi|239752555 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 195
Score = 376 bits (965), Expect = e-104
Identities = 184/190 (96%), Positives = 186/190 (97%), Gaps = 2/190 (1%)
Query: 359 MVNKLLQLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPKSCYLPSWLTP 418
MVNKLLQLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRP+SCYLPSWLTP
Sbjct: 1 MVNKLLQLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTP 60
Query: 419 QYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLV 478
QYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYL
Sbjct: 61 QYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYL- 119
Query: 479 SLSHDSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRF 538
+ DSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRF
Sbjct: 120 -CTSDSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRF 178
Query: 539 QVDKCFKHKV 548
QVDKCFKHKV
Sbjct: 179 QVDKCFKHKV 188
>gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens]
Length = 1428
Score = 372 bits (955), Expect = e-102
Identities = 354/1340 (26%), Positives = 585/1340 (43%), Gaps = 193/1340 (14%)
Query: 110 VFVQTDKPTYKPGQKDVNGIAQFFLDTYTF-TYPNITLKDPQNNRIFQWQNVTSFRNITQ 168
VF+QTDK YKP Q+ I F D + T NI +KDP++N I QW + S +
Sbjct: 131 VFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVIS 190
Query: 169 LSFQLISEPMFGDYWIVVKRNSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVD 228
+FQL S P+ GD+ I V+ N + T F V YVLPKFEVT+ P +++
Sbjct: 191 KTFQLSSHPILGDWSIQVQVNDQ-TYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGT 249
Query: 229 VCAKYTFGQPVQG--------------KTQIRVCREYFSSSNCEKNDNEICEQFIAQLEN 274
+ AKYT+G+PV+G K I + S+N ND E+ + + N
Sbjct: 250 ITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEM--KNVMDSSN 307
Query: 275 GCVSQIVNTKVFQLYRSGLFMTFHVAVIVTEFGTGNYCMQISEKTSVFITQLLGTVNFEN 334
G ++ L G + VTE TG + + T+VF Q + F +
Sbjct: 308 GL------SEYLDLSSPG---PVEILTTVTESVTG---ISRNVSTNVFFKQHDYIIEFFD 355
Query: 335 MDTFYRRGISYFGTLKFS--DPNNVPMVNK-------LLQLELNDEFIGNYTTDENGEA- 384
T + +++ T+K + D N + + + + Q + + G+ + ++ EA
Sbjct: 356 YTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAV 415
Query: 385 ---QFSIDTSDIFDPEFNL--KATYVRPKSCYLPSWLTPQYLDAHFLVSRFYSRTNSFLK 439
+++ S F EF + ++ ++ K+ +L S + H L + S+T LK
Sbjct: 416 QKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGS---KSSMAVHSLF-KSPSKTYIQLK 471
Query: 440 IVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLVSLSHDSGNFQHRISSSPIYTA 499
E ++ + VV+ + L +Y S + LV++ +
Sbjct: 472 TRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQ---LVAVGKQNSTM------------ 516
Query: 500 WNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVNIKFSNEQGLP 559
F L+ P A + VY + GEI++D ++ V FK+K+ + +S + P
Sbjct: 517 ------FSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEP 570
Query: 560 GSNASLYLQAA-PVLFCALGAVDGNVLLLKSEQQLSAESVYNMVPSIEPYGYFYHGLNLD 618
SL + P + AVD +V L+ + ++ E N+V +E Y Y+
Sbjct: 571 SEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITME---NVVHELELYNTGYY----- 622
Query: 619 DGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVCVMERRL 678
MF N + + + GL V T+ + K + +
Sbjct: 623 ----------LGMFMNS--------------FAVFQECGLWVLTDANLTKDYIDGVYDNA 658
Query: 679 PLPKPLYLETENYGPMHSVPSRIACRGENADYVEQAIIQTVRTNFPETWMWDLVSVDSSG 738
+ E E H V G + VR +FPETW+W ++
Sbjct: 659 EYAERFMEENEG----HIVDIHDFSLGSSPH---------VRKHFPETWIWLDTNMGYRI 705
Query: 739 SANLSFLIPDTITQWEASGFCVNGDVGFGISSTTT-LEVSQPFFIEIASPFSVVQNEQFD 797
+PD+IT W A+GF ++ D+G G+++T L+ QPFFI + P+SV++ E+F
Sbjct: 706 YQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFA 765
Query: 798 LIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSE-----VIQAGGRKTNIWTIIPK 852
L + F+YL E+ V +E+S ++ + + +IN + ++ + T ++ I P
Sbjct: 766 LEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPT 825
Query: 853 KLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEGIEKERTQSFLI-CTE 911
LG++ ITV A S +S D V + LV+ EGIEK +QS L+ T+
Sbjct: 826 HLGEIPITVTALSPTAS---------------DAVTQMILVKAEGIEKSYSQSILLDLTD 870
Query: 912 GAKASKQGVLDL--PNDVVEGSARGFFTVVGDILGLAMQNLV-VLQMPYGGGEQNAALLA 968
S L P + V GS R T +GD+LG ++ L +++MPYG GEQN A
Sbjct: 871 NRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFA 930
Query: 969 SDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQNQKGSIWLSA 1028
+ Y+LDYL +QLT+ ++ KA + GYQR+L ++ DGS+S F + GS WLSA
Sbjct: 931 PNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSA 990
Query: 1029 LTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWEGGDEEDISLTA 1088
+ ++ ID+NV +T WL QK++G F + G++ + +GG++ ++LTA
Sbjct: 991 FVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTA 1050
Query: 1089 YVVGMFFEAGLNSTFPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQ 1148
Y+V ++ ++ LE+ G+++ Y A++ YA + G K E+ L
Sbjct: 1051 YIVTSLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEA-LN 1109
Query: 1149 TLDQSATKLNNVIYWERERKPKTEEFPSFIPWAP-SAQTEKSCYVLLA-----VISRKIP 1202
L A + + +W ++ W P S E + Y LL+ S IP
Sbjct: 1110 MLTWRAEQEGGMQFWVSSESKLSDS------WQPRSLDIEVAAYALLSHFLQFQTSEGIP 1163
Query: 1203 DLTYASKIVQWLAQQMNSHGGFSSNQVINVGLILIAICGEEGLFSKNQNTVTFSSEGSSE 1262
I++WL++Q NS GGF+S Q V L A+ L + + + + G S
Sbjct: 1164 -------IMRWLSRQRNSLGGFASTQDTTVA--LKALSEFAALMNTERTNIQVTVTGPS- 1213
Query: 1263 IQFNGHNRLLVQRSEVTQAPGQYTVDVEGRGCTFIQATLKYNVLLPKKASG--------- 1313
+ +VQ P + G G Q + YNV KASG
Sbjct: 1214 ---SPSPLAVVQ-------PTAVNISANGFGFAICQLNVVYNV----KASGSSRRRRSIQ 1259
Query: 1314 ----FSLSLEIVKNY-SLTVFDLTVNLKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEEVN 1368
F L + + +N L DL V ++G +S M +++V +LSGF +I
Sbjct: 1260 NQEAFDLDVAVKENKDDLNHVDLNVCTSFSG-PGRSGMALMEVNLLSGFMVPSEAISLSE 1318
Query: 1369 NRSLIFHHKDSYIEYKDKIN 1388
+ + Y D +N
Sbjct: 1319 TVKKVEYDHGKLNLYLDSVN 1338
>gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]
Length = 1368
Score = 364 bits (935), Expect = e-100
Identities = 345/1314 (26%), Positives = 578/1314 (43%), Gaps = 184/1314 (14%)
Query: 140 TYPNITL-KDPQNNRIFQWQNVTSFRNITQLSFQLISEPMFGDYWIVVKRNSRKTVTHQF 198
++ +TL DP++N I QW + S + +FQL S P+ GD+ I V+ N + T F
Sbjct: 84 SFKTLTLPSDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQ-TYYQSF 142
Query: 199 AVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYTFGQPVQG--------------KTQ 244
V YVLPKFEVT+ P +++ + AKYT+G+PV+G K
Sbjct: 143 QVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKN 202
Query: 245 IRVCREYFSSSNCEKNDNEICEQFIAQLENGCVSQIVNTKVFQLYRSGLFMTFHVAVIVT 304
I + S+N ND E+ + + NG ++ L G + VT
Sbjct: 203 ITKTFKINGSANFSFNDEEM--KNVMDSSNGL------SEYLDLSSPG---PVEILTTVT 251
Query: 305 EFGTGNYCMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFS--DPNNVPMVNK 362
E TG + + T+VF Q + F + T + +++ T+K + D N + + +
Sbjct: 252 ESVTG---ISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEER 308
Query: 363 -------LLQLELNDEFIGNYTTDENGEA----QFSIDTSDIFDPEFNL--KATYVRPKS 409
+ Q + + G+ + ++ EA +++ S F EF + ++ ++ K+
Sbjct: 309 RNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKA 368
Query: 410 CYLPSWLTPQYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDD 469
+L S + H L + S+T LK E ++ + VV+ + L +Y
Sbjct: 369 YFLGS---KSSMAVHSLF-KSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVV 424
Query: 470 SNVKFFYLVSLSHDSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSG 529
S + LV++ + F L+ P A + VY + G
Sbjct: 425 SRGQ---LVAVGKQNSTM------------------FSLTPENSWTPKACVIVYYIEDDG 463
Query: 530 EIVADSVRFQVDKCFKHKVNIKFSNEQGLPGSNASLYLQAA-PVLFCALGAVDGNVLLLK 588
EI++D ++ V FK+K+ + +S + P SL + P + AVD +V L+
Sbjct: 464 EIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMN 523
Query: 589 SEQQLSAESVYNMVPSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGD 648
+ ++ E N+V +E Y Y+ MF N
Sbjct: 524 ASNDITME---NVVHELELYNTGYY---------------LGMFMNS------------- 552
Query: 649 IYNIVRNMGLKVFTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSRIACRGENA 708
+ + + GL V T+ + K + + + E E H V G +
Sbjct: 553 -FAVFQECGLWVLTDANLTKDYIDGVYDNAEYAERFMEENEG----HIVDIHDFSLGSSP 607
Query: 709 DYVEQAIIQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGI 768
VR +FPETW+W ++ +PD+IT W A+GF ++ D+G G+
Sbjct: 608 H---------VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGL 658
Query: 769 SSTTT-LEVSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANIN 827
++T L+ QPFFI + P+SV++ E+F L + F+YL E+ V +E+S ++ +
Sbjct: 659 TTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMT 718
Query: 828 TWKINGSE-----VIQAGGRKTNIWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLN 882
+ +IN + ++ + T ++ I P LG++ ITV A S +S
Sbjct: 719 SNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPTAS------------- 765
Query: 883 WKDTVVKSFLVEPEGIEKERTQSFLI-CTEGAKASKQGVLDL--PNDVVEGSARGFFTVV 939
D V + LV+ EGIEK +QS L+ T+ S L P + V GS R T +
Sbjct: 766 --DAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAI 823
Query: 940 GDILGLAMQNLV-VLQMPYGGGEQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSNG 998
GD+LG ++ L +++MPYG GEQN A + Y+LDYL +QLT+ ++ KA + G
Sbjct: 824 GDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQG 883
Query: 999 YQRQLSFKNSDGSYSVFWQQNQKGSIWLSALTFKTLERMKKFVFIDENVQKQTLIWLSSQ 1058
YQR+L ++ DGS+S F + GS WLSA + ++ ID+NV +T WL
Sbjct: 884 YQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGH 943
Query: 1059 QKTSGCFKNDGQLFNHAWEGGDEEDISLTAYVVGMFFEAGLNSTFPALRNALFCLEAALD 1118
QK++G F + G++ + +GG++ ++LTAY+V ++ ++ LE+
Sbjct: 944 QKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFS 1003
Query: 1119 SGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQSATKLNNVIYWERERKPKTEEFPSFI 1178
G+++ Y A++ YA + G K E+ L L A + + +W ++
Sbjct: 1004 RGISDNYTLALITYALSSVGSPKAKEA-LNMLTWRAEQEGGMQFWVSSESKLSDS----- 1057
Query: 1179 PWAP-SAQTEKSCYVLLA-----VISRKIPDLTYASKIVQWLAQQMNSHGGFSSNQVINV 1232
W P S E + Y LL+ S IP I++WL++Q NS GGF+S Q V
Sbjct: 1058 -WQPRSLDIEVAAYALLSHFLQFQTSEGIP-------IMRWLSRQRNSLGGFASTQDTTV 1109
Query: 1233 GLILIAICGEEGLFSKNQNTVTFSSEGS-SEIQF--NGHNRLLVQRSEVTQA-PGQYTVD 1288
L ++ + VT + S S ++F + HNRLL+Q +E+ P +
Sbjct: 1110 ALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNIS 1169
Query: 1289 VEGRGCTFIQATLKYNVLLPKKASG-------------FSLSLEIVKNY-SLTVFDLTVN 1334
G G Q + YNV KASG F L + + +N L DL V
Sbjct: 1170 ANGFGFAICQLNVVYNV----KASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVC 1225
Query: 1335 LKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEEVNNRSLIFHHKDSYIEYKDKIN 1388
++G +S M +++V +LSGF +I + + Y D +N
Sbjct: 1226 TSFSG-PGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVN 1278
>gi|169217713 PREDICTED: similar to Ovostatin homolog 2 [Homo sapiens]
Length = 189
Score = 278 bits (710), Expect = 3e-74
Identities = 138/138 (100%), Positives = 138/138 (100%)
Query: 1103 FPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQSATKLNNVIY 1162
FPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQSATKLNNVIY
Sbjct: 47 FPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQSATKLNNVIY 106
Query: 1163 WERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIVQWLAQQMNSHG 1222
WERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIVQWLAQQMNSHG
Sbjct: 107 WERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIVQWLAQQMNSHG 166
Query: 1223 GFSSNQVINVGLILIAIC 1240
GFSSNQVINVGLILIAIC
Sbjct: 167 GFSSNQVINVGLILIAIC 184
>gi|169217831 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 136
Score = 253 bits (647), Expect = 7e-67
Identities = 122/123 (99%), Positives = 123/123 (100%)
Query: 359 MVNKLLQLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPKSCYLPSWLTP 418
MVNKLLQLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRP+SCYLPSWLTP
Sbjct: 1 MVNKLLQLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTP 60
Query: 419 QYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLV 478
QYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLV
Sbjct: 61 QYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLV 120
Query: 479 SLS 481
SLS
Sbjct: 121 SLS 123
>gi|239755748 PREDICTED: ovostatin [Homo sapiens]
Length = 257
Score = 204 bits (519), Expect = 5e-52
Identities = 106/118 (89%), Positives = 109/118 (92%), Gaps = 1/118 (0%)
Query: 1257 SEGSSEI-QFNGHNRLLVQRSEVTQAPGQYTVDVEGRGCTFIQATLKYNVLLPKKASGFS 1315
SEGSSEI Q NGHNRLLVQRSEVTQAPGQYTVDVEG GCTFIQATLKYNVLLPKKASGFS
Sbjct: 73 SEGSSEIFQVNGHNRLLVQRSEVTQAPGQYTVDVEGHGCTFIQATLKYNVLLPKKASGFS 132
Query: 1316 LSLEIVKNYSLTVFDLTVNLKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEEVNNRSLI 1373
LSLEIVKNYS T FDLTV LKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEE+ N+ +
Sbjct: 133 LSLEIVKNYSSTAFDLTVTLKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEELENKGQV 190
>gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain
containing 8 [Homo sapiens]
Length = 1932
Score = 181 bits (459), Expect = 4e-45
Identities = 200/876 (22%), Positives = 372/876 (42%), Gaps = 115/876 (13%)
Query: 100 SVAIRSRENVVFVQTDKPTYKPGQKDVNGIAQFFLDTYTFTYPNIT---------LKDPQ 150
SV + R VF+QTDKP Y+P + + +T + PN+ + DP+
Sbjct: 167 SVTVDGRGASVFIQTDKPVYRPQHR-------VLISIFTVS-PNLRPVNEKLEAYILDPR 218
Query: 151 NNRIFQWQNVTSFR-NITQLSFQLISEPMFGDYWIVVKRNSRKTVTHQFAVKRYVLPKFE 209
+R+ +W+++ F IT +SF L +P+ G+++I V+ F V++YVLPKFE
Sbjct: 219 GSRMIEWRHLKPFCCGITNMSFPLSDQPVLGEWFIFVEMQGH-AYNKSFEVQKYVLPKFE 277
Query: 210 VTVNAPQTVTISDDEFQVDVCAKYTFGQPVQGKTQIRVCREYFSSSNCEKNDNEICEQFI 269
+ ++ P+ + D V A+YTFG+PV G I + + E + I
Sbjct: 278 LLIDPPRYIQDLDACETGTVRARYTFGKPVAGALMINMTVNGVGYYSHEVGRPVLRTTKI 337
Query: 270 AQLENG--CVSQIVNTKVFQLYRSGLFMTFHVAVIVTEFGTGNYCMQISEKTSVFITQLL 327
+ CV ++ V + +R + + V + G+ + + T V QL+
Sbjct: 338 LGSRDFDICVRDMIPADVPEHFRGRVSIWAMVTSV-----DGSQQVAFDDSTPVQ-RQLV 391
Query: 328 GTVNFENMDTFYRRGISYFGTLKFSDPNNVPMVNKLLQLELN----DEFIGNYTTDENGE 383
++ ++ G++Y G ++ S P+ P +Q++ D + + G
Sbjct: 392 DIRYSKDTRKQFKPGLAYVGKVELSYPDGSPAEGVTVQIKAELTPKDNIYTSEVVSQRGL 451
Query: 384 AQFSIDTSDIFDPEFNLKATYVRPKSCYLPSWLTP---QYLDAHFLVSRFYSRTNSFLKI 440
F I P A +V ++ + P QYL ++ + +YS + +L++
Sbjct: 452 VGFEI-------PSIPTSAQHVWLETKVMALNGKPVGAQYLPSYLSLGSWYSPSQCYLQL 504
Query: 441 VPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLVSL-----------SHDSGNFQH 489
P L+ + ++S+ S N +Y V+ +H +
Sbjct: 505 QPPSHPLQVGEE----AYFSVKSTC---PCNFTLYYEVAARGNIVLSGQQPAHTTQQRSK 557
Query: 490 RISSS---PIYTAWNGNFSFP---------------LSISADLAPAAVLFVYTLHPSGEI 531
R + + PI P L+++ + P L V+ + +GE
Sbjct: 558 RAAPALEKPIRLTHLSETEPPPAPEAEVDVCVTSLHLAVTPSMVPLGRLLVFYVRENGEG 617
Query: 532 VADSVRFQVDKCFKHKVNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQ 591
VADS++F V+ F+++V++ +S + PG L ++AA + AVD +V LL+S
Sbjct: 618 VADSLQFAVETFFENQVSVTYSANETQPGEVVDLRIRAARGSCVCVAAVDKSVYLLRSGF 677
Query: 592 QLSAESVYNMVPSIEPYGYFYHGLNLDDGKEDPC-IPQRDMFYNGLYYTPVSNYGDGDIY 650
+L+ V+ + + F G++ +DG + + + ++ P D
Sbjct: 678 RLTPAQVFQELEDYDVSDSF--GVSREDGPFWWAGLTAQRRRRSSVFPWPWGITKDSGF- 734
Query: 651 NIVRNMGLKVFTN---LHYRKPEVCVMERRLPLPKPLYLETENYGPMHSV-PSRIACRGE 706
GL V T+ L++R+ + +P +P + G + +V PSR R E
Sbjct: 735 -AFTETGLVVMTDRVSLNHRQDGGLYTDEAVPAFQP------HTGSLVAVAPSRHPPRTE 787
Query: 707 NADYVEQAIIQTVRTNFPETWMWDLVSV-DSSGSANLSFLIPDTITQWEASGFCVNGDVG 765
RT FPETW+W +++ D SG LS +PD+IT W ++ G
Sbjct: 788 KRK----------RTFFPETWIWHCLNISDPSGEGTLSVKVPDSITSWVGEAVALSTSQG 837
Query: 766 FGISSTTTLEVSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEAN 825
GI+ + L+ +PFF++ P +++ EQ + ++ ++Y+ TC E+ +++ + +
Sbjct: 838 LGIAEPSLLKTFKPFFVDFMLPALIIRGEQVKIPLSVYNYMGTCAEVYMKLSVPKGIQFV 897
Query: 826 INTWKIN-GSEVIQAGGRKTNIWTIIP-KKLGKVNITVVAESKQSSACPNEGMEQQKLNW 883
+ K + ++ A G IW ++ LG NIT A + + C +G +
Sbjct: 898 GHPGKRHVTKKMCVAPGEAEPIWVVLSFSDLGLNNITAKALAYGDTNCCRDGRSSKHPEE 957
Query: 884 K----------DTVVKSFLVEPEGIEKERTQSFLIC 909
D V +S +VE EG+ + T S C
Sbjct: 958 NHADRRVPIGVDHVRRSVMVEAEGVPRAYTYSAFFC 993
Score = 178 bits (451), Expect = 4e-44
Identities = 125/417 (29%), Positives = 203/417 (48%), Gaps = 16/417 (3%)
Query: 916 SKQGVLDLPNDVVEGSARGFFTVVGDILGLAMQNLV-VLQMPYGGGEQNAALLASDTYVL 974
S+ L +P+ + GS R +++GD++G + +L +L++P+G GEQN A + +VL
Sbjct: 1147 SEAFTLGVPHGAIPGSERATASIIGDVMGPTLNHLNNLLRLPFGCGEQNMIHFAPNVFVL 1206
Query: 975 DYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQNQKGSIWLSALTFKTL 1034
YL+ T+QL+ EV+ + L GYQRQL++K DGSYS F +++ GS+WL+A K+
Sbjct: 1207 KYLQKTQQLSPEVERETTDYLVQGYQRQLTYKRQDGSYSAFGERDASGSMWLTAFVLKSF 1266
Query: 1035 ERMKKFVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWEGGDEEDISLTAYVVGMF 1094
+ + F+F+D W+ QQ+ G F G++ N +GG + LTAYVV
Sbjct: 1267 AQARSFIFVDPRELAAAKSWIIQQQQADGSFLAVGRVLNKDIQGGIHGTVPLTAYVVVAL 1326
Query: 1095 FEAGLNSTFP--ALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQ 1152
E G S + A LE+A + + Y+ A+ YA L E+ L+ L
Sbjct: 1327 LETGTASEEERGSTDKARHFLESAAPLAM-DPYSCALTTYALTLLRSPAAPEA-LRKLRS 1384
Query: 1153 SATKLNNVIYWERERKPKTEE--FPSFIPWAP----SAQTEKSCYVLLAVISRKIPDLTY 1206
A + V +W ++ F SF SA+ E + Y LL + D+
Sbjct: 1385 LAIMRDGVTHWSLSNSWDVDKGTFLSFSDRVSQSVVSAEVEMTAYALLTY--TLLGDVAA 1442
Query: 1207 ASKIVQWLAQQMNSHGGFSSNQVINVGLILI---AICGEEGLFSKNQNTVTFSSEGSSEI 1263
A +V+WL+QQ N+ GGFSS Q V L + AI G + + + + +
Sbjct: 1443 ALPVVKWLSQQRNALGGFSSTQDTCVALQALAEYAILSYAGGINLTVSLASTNLDYQETF 1502
Query: 1264 QFNGHNRLLVQRSEVTQAPGQYTVDVEGRGCTFIQATLKYNVLLPKKASGFSLSLEI 1320
+ + N+ ++Q + + P V +G GC +Q + YNV P F L + +
Sbjct: 1503 ELHRTNQKVLQTAAIPSLPTGLFVSAKGDGCCLMQIDVTYNVPDPVAKPAFQLLVSL 1559
>gi|115298678 complement component 3 precursor [Homo sapiens]
Length = 1663
Score = 171 bits (433), Expect = 5e-42
Identities = 326/1533 (21%), Positives = 591/1533 (38%), Gaps = 227/1533 (14%)
Query: 1 MTGSHLSHDSWQYVLLIPSVLQEGSLDKACAQLFNLTESVVLTVSLNYGEVQTKIFEENV 60
+T L+ S Y ++ P++L+ S + + + V +TV+++ + +
Sbjct: 14 LTHLPLALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFPGKKLVLSSEK 73
Query: 61 T----GENFFKCISFEVPQARSDPLA-----FITFSAKGATLNLEERRSVAIRSRENVVF 111
T N ++F +P R F+T A T +E+ V+++S +F
Sbjct: 74 TVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEKVVLVSLQS--GYLF 131
Query: 112 VQTDKPTYKPGQKDVNGIAQFFLDTYTFTYPNITLKDPQNNR-IFQWQNVTSFRN---IT 167
+QTDK Y PG + I F ++ + + +N I Q+ S +N +
Sbjct: 132 IQTDKTIYTPGSTVLYRI--FTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVL 189
Query: 168 QLSFQLISEPMFGDYWI--VVKRNSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTISDDE- 224
LS+ + G + I + + ++ + +F VK YVLP FEV V + +E
Sbjct: 190 PLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEK 249
Query: 225 -FQVDVCAKYTFGQPVQGKTQIRVCREYFSSSNCEKNDNEICEQFIAQLENGCVSQIVNT 283
+V + A++ +G+ V+G + F + E+ + +E+G +++
Sbjct: 250 GLEVTITARFLYGKKVEGTAFV-----IFGIQDGEQRISLPESLKRIPIEDGSGEVVLSR 304
Query: 284 KVF----------QLYRSGLFMTFHVAVIVTEFGTGNYCMQISEKTSVFITQLLGTVNFE 333
KV L L+++ A ++ G+ M +E++ + I ++F
Sbjct: 305 KVLLDGVQNPRAEDLVGKSLYVS---ATVILHSGSD---MVQAERSGIPIVTSPYQIHFT 358
Query: 334 NMDTFYRRGISYFGTLKFSDPNNVPMVNKLLQLELNDEFIGNYTTDENGEAQFSIDTSDI 393
+++ G+ + + ++P+ P + ++ D T +G A+ SI+T
Sbjct: 359 KTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTV--QSLTQGDGVAKLSINTHPS 416
Query: 394 FDPEFNLKATYVRPKSCYLPSWLTPQYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQK 453
P L T K + + + A L +N++L + + E +
Sbjct: 417 QKP---LSITVRTKKQELSEAEQATRTMQA--LPYSTVGNSNNYLHL--SVLRTELRPGE 469
Query: 454 VVTVHYSLNSEAYEDDSNVKFFYLVSLSHDSGNFQHRISSSPIYTAWNGNFSFPLSISAD 513
+ V++ L + + K Y L + G + + PLSI+ D
Sbjct: 470 TLNVNFLLRMDRAHE---AKIRYYTYLIMNKGRLLK--AGRQVREPGQDLVVLPLSITTD 524
Query: 514 LAPAAVLFVY--TLHPSG--EIVADSVRFQV-DKCFKHKVNIKFSNE--QGLPGSNASLY 566
P+ L Y + SG E+VADSV V D C V +E Q +PG +L
Sbjct: 525 FIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLK 584
Query: 567 LQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYNMVPSIEPYGYFYHGLNLDDGKEDPCI 626
++ L AVD V +L + +L+ ++++V D G C
Sbjct: 585 IEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKA------------DIG----CT 628
Query: 627 PQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVCVMERRLP----LPK 682
P Y G++ + + L+ R+ V + E+R+ PK
Sbjct: 629 PGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAARRRRSVQLTEKRMDKVGKYPK 688
Query: 683 PL---------------------------------YLETENY----GPMHSVPSRIACRG 705
L +L+ NY H+ S +
Sbjct: 689 ELRKCCEDGMRENPMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLAR 748
Query: 706 ENAD---YVEQAIIQTVRTNFPETWMW---DLVSVDSSGSAN--LSFLIPDTITQWEASG 757
N D E+ I+ R+ FPE+W+W DL +G + ++ + D+IT WE
Sbjct: 749 SNLDEDIIAEENIVS--RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILA 806
Query: 758 FCVNGDVGFGISSTTTLEVSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVE 817
++ G ++ + V Q FFI++ P+SVV+NEQ ++ ++Y E+ V+VE
Sbjct: 807 VSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQN-QELKVRVE 865
Query: 818 ESQNYE-ANINTWKINGSEVIQAGGRKTNI--WTIIPKKLGKVNITVVAESKQSSACPNE 874
N ++ T K + + + + + I+P K G + V A
Sbjct: 866 LLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFI---- 921
Query: 875 GMEQQKLNWKDTVVKSFLVEPEGIEKERTQSF------LICTEGAKASKQGVLDLPNDVV 928
D V KS V PEGI +T + + EG + DL + V
Sbjct: 922 ---------SDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVP 972
Query: 929 EGSARGFFTVVGDILGLAMQNLV-------VLQMPYGGGEQNAALLASDTYVLDYLKSTE 981
+ + + G + ++ V ++ P G GEQN + + YL TE
Sbjct: 973 DTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETE 1032
Query: 982 QLTE---EVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQNQKGSIWLSALTFKTLERMK 1038
Q + E + A L+ GY +QL+F+ +++ F + S WL+A K
Sbjct: 1033 QWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAF--VKRAPSTWLTAYVVKVFSLAV 1090
Query: 1039 KFVFIDENVQKQTLIWL-SSQQKTSGCFKNDGQLFNHAWEGG----DEEDISLTAYVVGM 1093
+ ID V + WL +QK G F+ D + + GG +E+D++LTA+V+
Sbjct: 1091 NLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLIS 1150
Query: 1094 FFEA------GLNSTFPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLL 1147
EA +NS ++ A LEA + Y AI YA A G+ K
Sbjct: 1151 LQEAKDICEEQVNSLPGSITKAGDFLEANY-MNLQRSYTVAIAGYALAQMGRLKG----- 1204
Query: 1148 QTLDQSATKLNNVIYWERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYA 1207
L++ T + WE P E + Y LLA++ K D +
Sbjct: 1205 PLLNKFLTTAKDKNRWED-------------PGKQLYNVEATSYALLALLQLK--DFDFV 1249
Query: 1208 SKIVQWLAQQMNSHGGFSSNQVINVGLILIAICGEEGLFSKNQN---TVTFSSEGSSEIQ 1264
+V+WL +Q GG+ S Q + +A ++ + N ++ S SS+I
Sbjct: 1250 PPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSR-SSKIT 1308
Query: 1265 FNGH-NRLLVQRSEVTQAPGQYTVDVEGRGCTFIQATLKYNVLLPKKASGFSLSLEIV-- 1321
H + RSE T+ +TV EG+G + Y+ + + L++
Sbjct: 1309 HRIHWESASLLRSEETKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIK 1368
Query: 1322 --------KNYSLTVFDLTVNLKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEEVNN---- 1369
+ L + +Y G ++ ++M ++D+ M++GF P ++++ N
Sbjct: 1369 PAPETEKRPQDAKNTMILEICTRYRGDQD-ATMSILDISMMTGFAPDTDDLKQLANGVDR 1427
Query: 1370 ------RSLIFHHKDSYIEYKDKI----NTCLA 1392
F +++ I Y DK+ + CLA
Sbjct: 1428 YISKYELDKAFSDRNTLIIYLDKVSHSEDDCLA 1460
>gi|169218213 PREDICTED: similar to complement component C3, partial
[Homo sapiens]
Length = 1295
Score = 157 bits (396), Expect = 9e-38
Identities = 290/1341 (21%), Positives = 516/1341 (38%), Gaps = 197/1341 (14%)
Query: 1 MTGSHLSHDSWQYVLLIPSVLQEGSLDKACAQLFNLTESVVLTVSLNYGEVQTKIFEENV 60
+T L+ S Y ++ P++L+ S + + + V +TV+++ + +
Sbjct: 14 LTHLPLALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFPGKKLVLSSEK 73
Query: 61 T----GENFFKCISFEVPQARSDPLA-----FITFSAKGATLNLEERRSVAIRSRENVVF 111
T N ++F +P R F+T A T +E+ V+++S +F
Sbjct: 74 TVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEKVVLVSLQS--GYLF 131
Query: 112 VQTDKPTYKPGQKDVNGIAQFFLDTYTFTYPNITLKDPQNNR-IFQWQNVTSFRN---IT 167
+QTDK Y PG + I F ++ + + +N I Q+ S +N +
Sbjct: 132 IQTDKTIYTPGSTVLYRI--FTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVL 189
Query: 168 QLSFQLISEPMFGDYWI--VVKRNSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTISDDE- 224
LS+ + G + I + + ++ + +F VK YVLP FEV V + +E
Sbjct: 190 PLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEK 249
Query: 225 -FQVDVCAKYTFGQPVQGKTQIRVCREYFSSSNCEKNDNEICEQFIAQLENGCVSQIVNT 283
+V + A++ +G+ V+G + F + E+ + +E+G +++
Sbjct: 250 GLEVTITARFLYGKKVEGTAFV-----IFGIQDGEQRISLPESLKRIPIEDGSGEVVLSR 304
Query: 284 KVF----------QLYRSGLFMTFHVAVIVTEFGTGNYCMQISEKTSVFITQLLGTVNFE 333
KV L L+++ A ++ G+ M +E++ + I ++F
Sbjct: 305 KVLLDGVQNLRAEDLVGKSLYVS---ATVILHSGSD---MVQAERSGIPIVTSPYQIHFT 358
Query: 334 NMDTFYRRGISYFGTLKFSDPNNVPMVNKLLQLELNDEFIGNYTTDENGEAQFSIDTSDI 393
+++ G+ + + ++P+ P + ++ D T +G A+ SI+T
Sbjct: 359 KTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTV--QSLTQGDGVAKLSINTHPS 416
Query: 394 FDPEFNLKATYVRPKSCYLPSWLTPQYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQK 453
P L T K + + + A L +N++L + + E +
Sbjct: 417 QKP---LSITVRTKKQELSEAEQATRTMQA--LPYSTVGNSNNYLHL--SVLRTELRPGE 469
Query: 454 VVTVHYSLNSEAYEDDSNVKFFYLVSLSHDSGNFQHRISSSPIYTAWNGNFSFPLSISAD 513
+ V++ L + + K Y L + G + + PLSI+ D
Sbjct: 470 TLNVNFLLRMDRAHE---AKIRYYTYLIMNKGRLLK--AGRQVREPGQDLVVLPLSITTD 524
Query: 514 LAPAAVLFVY--TLHPSG--EIVADSVRFQV-DKCFKHKVNIKFSNE--QGLPGSNASLY 566
P+ L Y + SG E+VADSV V D C V +E Q +PG +L
Sbjct: 525 FIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLK 584
Query: 567 LQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYNMVPSIEPYGYFYHGLNLDDGKEDPCI 626
++ L AVD V +L + +L+ ++++V D G C
Sbjct: 585 IEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKA------------DIG----CT 628
Query: 627 PQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVCVMERRLP----LPK 682
P Y G++ + + L+ R+ V + E+R+ PK
Sbjct: 629 PGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAARRRRSVQLTEKRMDKVGKYPK 688
Query: 683 PL---------------------------------YLETENY----GPMHSVPSRIACRG 705
L +L+ NY H+ S +
Sbjct: 689 ELRKCCEDGMRENPMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLAR 748
Query: 706 ENAD---YVEQAIIQTVRTNFPETWMW---DLVSVDSSGSAN--LSFLIPDTITQWEASG 757
N D E+ I+ R+ FPE+W+W DL +G + ++ + D+IT WE
Sbjct: 749 SNLDEDIIAEENIVS--RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILA 806
Query: 758 FCVNGDVGFGISSTTTLEVSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVE 817
++ G ++ + V Q FFI++ P+SVV+NEQ ++ ++Y E+ V+VE
Sbjct: 807 VSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQN-QELKVRVE 865
Query: 818 ESQNYE-ANINTWKINGSEVIQAGGRKTNI--WTIIPKKLGKVNITVVAESKQSSACPNE 874
N ++ T K + + + + + I+P K G + V A
Sbjct: 866 LLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFI---- 921
Query: 875 GMEQQKLNWKDTVVKSFLVEPEGIEKERTQSF------LICTEGAKASKQGVLDLPNDVV 928
D V KS V PEGI +T + + EG + DL + V
Sbjct: 922 ---------SDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVP 972
Query: 929 EGSARGFFTVVGDILGLAMQNLV-------VLQMPYGGGEQNAALLASDTYVLDYLKSTE 981
+ + + G + ++ V ++ P G GEQN + + YL TE
Sbjct: 973 DTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETE 1032
Query: 982 QLTE---EVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQNQKGSIWLSALTFKTLERMK 1038
Q + E + A L+ GY +QL+F+ +++ F + S WL+A K
Sbjct: 1033 QWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAF--VKRAPSTWLTAYVVKVFSLAV 1090
Query: 1039 KFVFIDENVQKQTLIWL-SSQQKTSGCFKNDGQLFNHAWEGG----DEEDISLTAYVVGM 1093
+ ID V + WL +QK G F+ D + + GG +E+D++LTA+V+
Sbjct: 1091 NLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLIS 1150
Query: 1094 FFEA------GLNSTFPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLL 1147
EA +NS ++ A LEA + Y AI YA A G+ K
Sbjct: 1151 LQEAKDICEEQVNSLPGSITKAGDFLEANY-MNLQRSYTVAIAGYALAQMGRLKG----- 1204
Query: 1148 QTLDQSATKLNNVIYWERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYA 1207
L++ T + WE P E + Y LLA++ K D +
Sbjct: 1205 PLLNKFLTTAKDKNRWED-------------PGKQLYNVEATSYALLALLQLK--DFDFV 1249
Query: 1208 SKIVQWLAQQMNSHGGFSSNQ 1228
+V+WL +Q GG+ S Q
Sbjct: 1250 PPVVRWLNEQRYYGGGYGSTQ 1270
>gi|178557739 complement component 4B preproprotein [Homo sapiens]
Length = 1744
Score = 136 bits (343), Expect = 1e-31
Identities = 159/649 (24%), Positives = 263/649 (40%), Gaps = 68/649 (10%)
Query: 719 VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQ 778
VR+ FPE W+W + +VD L+ +PD++T WE G ++ G +++ L V +
Sbjct: 774 VRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFR 831
Query: 779 PFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSEVIQ 838
F + + P SV + EQ +L ++YL+ + +SV V + + ++
Sbjct: 832 EFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGL-CLAGGGGLAQQVLVP 890
Query: 839 AGGRKTNIWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEG- 897
AG + ++++P V++ VVA + D V K +E EG
Sbjct: 891 AGSARPVAFSVVPTAATAVSLKVVARG------------SFEFPVGDAVSKVLQIEKEGA 938
Query: 898 IEKERTQSFL--ICTEGAKASKQGVLDLPNDVVEGSARGFFTVVG----DILG----LAM 947
I +E L + G G D PN + +G + V D LG L+
Sbjct: 939 IHREELVYELNPLDHRGRTLEIPGNSD-PNMIPDGDFNSYVRVTASDPLDTLGSEGALSP 997
Query: 948 QNLV-VLQMPYGGGEQNAALLASDTYVLDYLKSTEQ---LTEEVQSKAFFLLSNGYQRQL 1003
+ +L++P G GEQ LA YL TEQ L E + A L+ GY R
Sbjct: 998 GGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQ 1057
Query: 1004 SFKNSDGSYSVFWQQNQKGSIWLSALTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSG 1063
F+ +DGSY+ + + S WL+A K L ++ V ++T WL SQQ+ G
Sbjct: 1058 QFRKADGSYAAWLSRG--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADG 1115
Query: 1064 CFKNDGQLFNHAWEG---GDEEDISLTAYV-------VGMFFEAGL----NSTFPALRNA 1109
F++ + + + +G G++E ++LTA+V + +F + G ++ A
Sbjct: 1116 SFQDLSPVIHRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKA 1175
Query: 1110 LFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLL-QTLDQSATKLNNVIYW----- 1163
L +G+ + AI AYA L + + L A + + +YW
Sbjct: 1176 SSFLGEKASAGLLGAHAAAITAYALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTG 1235
Query: 1164 ------ERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIVQWLAQQ 1217
P+ P +P AP+ E + Y LL ++ + A + WL +Q
Sbjct: 1236 SQSNAVSPTPAPRNPSDP--MPQAPALWIETTAYALLHLLLHE-GKAEMADQAAAWLTRQ 1292
Query: 1218 MNSHGGFSSNQVINVGL-ILIAICGEEGLFSKNQNTVTFSSEG-----SSEIQFNGHNRL 1271
+ GGF S Q + L L A + VT SS G S +Q N
Sbjct: 1293 GSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIR 1352
Query: 1272 LVQRSEVTQAPGQYTVDVEGRGCTFIQATLKYNVLLPKKASGFSLSLEI 1320
++ + V V G ++ YNVL K + L +E+
Sbjct: 1353 GLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEV 1401
Score = 60.8 bits (146), Expect = 9e-09
Identities = 55/157 (35%), Positives = 80/157 (50%), Gaps = 24/157 (15%)
Query: 105 SRENVVFVQTDKPTYKPGQKDVNGIAQFFLD------TYTFTYPNITLKDPQNNRIFQWQ 158
SR +F+QTD+P Y PGQ+ + F LD T T T + +++ R+ + +
Sbjct: 136 SRRGHLFLQTDQPIYNPGQRVRYRV--FALDQKMRPSTDTIT---VMVENSHGLRVRK-K 189
Query: 159 NVTSFRNITQLSFQL--ISEPMFGDYWIVVKRNS---RKTVTHQFAVKRYVLPKFEV--T 211
V +I Q F + ISEP W + R S + QF VK+YVLP FEV T
Sbjct: 190 EVYMPSSIFQDDFVIPDISEP---GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKIT 246
Query: 212 VNAPQTVTISD--DEFQVDVCAKYTFGQPVQGKTQIR 246
P +T+ DE Q+D+ A+Y +G+PVQG +R
Sbjct: 247 PGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVR 283
>gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo
sapiens]
Length = 1698
Score = 135 bits (341), Expect = 2e-31
Identities = 159/649 (24%), Positives = 264/649 (40%), Gaps = 68/649 (10%)
Query: 719 VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQ 778
VR+ FPE W+W + +VD L+ +PD++T WE G ++ G +++ L V +
Sbjct: 774 VRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFR 831
Query: 779 PFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSEVIQ 838
F + + P SV + EQ +L ++YL+ + +SV V + + ++
Sbjct: 832 EFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGL-CLAGGGGLAQQVLVP 890
Query: 839 AGGRKTNIWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEG- 897
AG + ++++P V++ VVA + D V K +E EG
Sbjct: 891 AGSARPVAFSVVPTAAAAVSLKVVARG------------SFEFPVGDAVSKVLQIEKEGA 938
Query: 898 IEKERTQSFL--ICTEGAKASKQGVLDLPNDVVEGSARGFFTVVG----DILG----LAM 947
I +E L + G G D PN + +G + V D LG L+
Sbjct: 939 IHREELVYELNPLDHRGRTLEIPGNSD-PNMIPDGDFNSYVRVTASDPLDTLGSEGALSP 997
Query: 948 QNLV-VLQMPYGGGEQNAALLASDTYVLDYLKSTEQ---LTEEVQSKAFFLLSNGYQRQL 1003
+ +L++P G GEQ LA YL TEQ L E + A L+ GY R
Sbjct: 998 GGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQ 1057
Query: 1004 SFKNSDGSYSVFWQQNQKGSIWLSALTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSG 1063
F+ +DGSY+ + ++ S WL+A K L ++ V ++T WL SQQ+ G
Sbjct: 1058 QFRKADGSYAAWLSRD--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADG 1115
Query: 1064 CFKNDGQLFNHAWEG---GDEEDISLTAYV-------VGMFFEAGL----NSTFPALRNA 1109
F++ + + + +G G++E ++LTA+V + +F + G ++ A
Sbjct: 1116 SFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKA 1175
Query: 1110 LFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLL-QTLDQSATKLNNVIYW----- 1163
L +G+ + AI AYA L + + L A + + +YW
Sbjct: 1176 NSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTG 1235
Query: 1164 ------ERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIVQWLAQQ 1217
P+ P +P AP+ E + Y LL ++ + A + WL +Q
Sbjct: 1236 SQSNAVSPTPAPRNPSDP--MPQAPALWIETTAYALLHLLLHE-GKAEMADQAAAWLTRQ 1292
Query: 1218 MNSHGGFSSNQVINVGL-ILIAICGEEGLFSKNQNTVTFSSEG-----SSEIQFNGHNRL 1271
+ GGF S Q + L L A + VT SS G S +Q N
Sbjct: 1293 GSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIR 1352
Query: 1272 LVQRSEVTQAPGQYTVDVEGRGCTFIQATLKYNVLLPKKASGFSLSLEI 1320
++ + V V G ++ YNVL K + L +E+
Sbjct: 1353 GLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEV 1401
Score = 60.8 bits (146), Expect = 9e-09
Identities = 55/157 (35%), Positives = 80/157 (50%), Gaps = 24/157 (15%)
Query: 105 SRENVVFVQTDKPTYKPGQKDVNGIAQFFLD------TYTFTYPNITLKDPQNNRIFQWQ 158
SR +F+QTD+P Y PGQ+ + F LD T T T + +++ R+ + +
Sbjct: 136 SRRGHLFLQTDQPIYNPGQRVRYRV--FALDQKMRPSTDTIT---VMVENSHGLRVRK-K 189
Query: 159 NVTSFRNITQLSFQL--ISEPMFGDYWIVVKRNS---RKTVTHQFAVKRYVLPKFEV--T 211
V +I Q F + ISEP W + R S + QF VK+YVLP FEV T
Sbjct: 190 EVYMPSSIFQDDFVIPDISEP---GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKIT 246
Query: 212 VNAPQTVTISD--DEFQVDVCAKYTFGQPVQGKTQIR 246
P +T+ DE Q+D+ A+Y +G+PVQG +R
Sbjct: 247 PGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVR 283
>gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo
sapiens]
Length = 1744
Score = 135 bits (341), Expect = 2e-31
Identities = 159/649 (24%), Positives = 264/649 (40%), Gaps = 68/649 (10%)
Query: 719 VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQ 778
VR+ FPE W+W + +VD L+ +PD++T WE G ++ G +++ L V +
Sbjct: 774 VRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFR 831
Query: 779 PFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSEVIQ 838
F + + P SV + EQ +L ++YL+ + +SV V + + ++
Sbjct: 832 EFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGL-CLAGGGGLAQQVLVP 890
Query: 839 AGGRKTNIWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEG- 897
AG + ++++P V++ VVA + D V K +E EG
Sbjct: 891 AGSARPVAFSVVPTAAAAVSLKVVARG------------SFEFPVGDAVSKVLQIEKEGA 938
Query: 898 IEKERTQSFL--ICTEGAKASKQGVLDLPNDVVEGSARGFFTVVG----DILG----LAM 947
I +E L + G G D PN + +G + V D LG L+
Sbjct: 939 IHREELVYELNPLDHRGRTLEIPGNSD-PNMIPDGDFNSYVRVTASDPLDTLGSEGALSP 997
Query: 948 QNLV-VLQMPYGGGEQNAALLASDTYVLDYLKSTEQ---LTEEVQSKAFFLLSNGYQRQL 1003
+ +L++P G GEQ LA YL TEQ L E + A L+ GY R
Sbjct: 998 GGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQ 1057
Query: 1004 SFKNSDGSYSVFWQQNQKGSIWLSALTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSG 1063
F+ +DGSY+ + ++ S WL+A K L ++ V ++T WL SQQ+ G
Sbjct: 1058 QFRKADGSYAAWLSRD--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADG 1115
Query: 1064 CFKNDGQLFNHAWEG---GDEEDISLTAYV-------VGMFFEAGL----NSTFPALRNA 1109
F++ + + + +G G++E ++LTA+V + +F + G ++ A
Sbjct: 1116 SFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKA 1175
Query: 1110 LFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLL-QTLDQSATKLNNVIYW----- 1163
L +G+ + AI AYA L + + L A + + +YW
Sbjct: 1176 NSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTG 1235
Query: 1164 ------ERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIVQWLAQQ 1217
P+ P +P AP+ E + Y LL ++ + A + WL +Q
Sbjct: 1236 SQSNAVSPTPAPRNPSDP--MPQAPALWIETTAYALLHLLLHE-GKAEMADQAAAWLTRQ 1292
Query: 1218 MNSHGGFSSNQVINVGL-ILIAICGEEGLFSKNQNTVTFSSEG-----SSEIQFNGHNRL 1271
+ GGF S Q + L L A + VT SS G S +Q N
Sbjct: 1293 GSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIR 1352
Query: 1272 LVQRSEVTQAPGQYTVDVEGRGCTFIQATLKYNVLLPKKASGFSLSLEI 1320
++ + V V G ++ YNVL K + L +E+
Sbjct: 1353 GLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEV 1401
Score = 60.8 bits (146), Expect = 9e-09
Identities = 55/157 (35%), Positives = 80/157 (50%), Gaps = 24/157 (15%)
Query: 105 SRENVVFVQTDKPTYKPGQKDVNGIAQFFLD------TYTFTYPNITLKDPQNNRIFQWQ 158
SR +F+QTD+P Y PGQ+ + F LD T T T + +++ R+ + +
Sbjct: 136 SRRGHLFLQTDQPIYNPGQRVRYRV--FALDQKMRPSTDTIT---VMVENSHGLRVRK-K 189
Query: 159 NVTSFRNITQLSFQL--ISEPMFGDYWIVVKRNS---RKTVTHQFAVKRYVLPKFEV--T 211
V +I Q F + ISEP W + R S + QF VK+YVLP FEV T
Sbjct: 190 EVYMPSSIFQDDFVIPDISEP---GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKIT 246
Query: 212 VNAPQTVTISD--DEFQVDVCAKYTFGQPVQGKTQIR 246
P +T+ DE Q+D+ A+Y +G+PVQG +R
Sbjct: 247 PGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVR 283
>gi|67190748 complement component 4A preproprotein [Homo sapiens]
Length = 1744
Score = 135 bits (339), Expect = 4e-31
Identities = 159/649 (24%), Positives = 264/649 (40%), Gaps = 68/649 (10%)
Query: 719 VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQ 778
VR+ FPE W+W + +VD L+ +PD++T WE G ++ G +++ L V +
Sbjct: 774 VRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFR 831
Query: 779 PFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSEVIQ 838
F + + P SV + EQ +L ++YL+ + +SV V + + ++
Sbjct: 832 EFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGL-CLAGGGGLAQQVLVP 890
Query: 839 AGGRKTNIWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEG- 897
AG + ++++P V++ VVA + D V K +E EG
Sbjct: 891 AGSARPVAFSVVPTAAAAVSLKVVARG------------SFEFPVGDAVSKVLQIEKEGA 938
Query: 898 IEKERTQSFL--ICTEGAKASKQGVLDLPNDVVEGSARGFFTVVG----DILG----LAM 947
I +E L + G G D PN + +G + V D LG L+
Sbjct: 939 IHREELVYELNPLDHRGRTLEIPGNSD-PNMIPDGDFNSYVRVTASDPLDTLGSEGALSP 997
Query: 948 QNLV-VLQMPYGGGEQNAALLASDTYVLDYLKSTEQ---LTEEVQSKAFFLLSNGYQRQL 1003
+ +L++P G GEQ LA YL TEQ L E + A L+ GY R
Sbjct: 998 GGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQ 1057
Query: 1004 SFKNSDGSYSVFWQQNQKGSIWLSALTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSG 1063
F+ +DGSY+ + ++ S WL+A K L ++ V ++T WL SQQ+ G
Sbjct: 1058 QFRKADGSYAAWLSRD--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADG 1115
Query: 1064 CFKNDGQLFNHAWEG---GDEEDISLTAYV-------VGMFFEAGL----NSTFPALRNA 1109
F++ + + + +G G++E ++LTA+V + +F + G ++ A
Sbjct: 1116 SFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKA 1175
Query: 1110 LFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLL-QTLDQSATKLNNVIYW----- 1163
L +G+ + AI AYA L + + L A + + +YW
Sbjct: 1176 NSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTG 1235
Query: 1164 ------ERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIVQWLAQQ 1217
P+ P +P AP+ E + Y LL ++ + A + WL +Q
Sbjct: 1236 SQSNAVSPTPAPRNPSDP--MPQAPALWIETTAYALLHLLLHE-GKAEMADQASAWLTRQ 1292
Query: 1218 MNSHGGFSSNQVINVGL-ILIAICGEEGLFSKNQNTVTFSSEG-----SSEIQFNGHNRL 1271
+ GGF S Q + L L A + VT SS G S +Q N
Sbjct: 1293 GSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIR 1352
Query: 1272 LVQRSEVTQAPGQYTVDVEGRGCTFIQATLKYNVLLPKKASGFSLSLEI 1320
++ + V V G ++ YNVL K + L +E+
Sbjct: 1353 GLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEV 1401
Score = 60.8 bits (146), Expect = 9e-09
Identities = 55/157 (35%), Positives = 80/157 (50%), Gaps = 24/157 (15%)
Query: 105 SRENVVFVQTDKPTYKPGQKDVNGIAQFFLD------TYTFTYPNITLKDPQNNRIFQWQ 158
SR +F+QTD+P Y PGQ+ + F LD T T T + +++ R+ + +
Sbjct: 136 SRRGHLFLQTDQPIYNPGQRVRYRV--FALDQKMRPSTDTIT---VMVENSHGLRVRK-K 189
Query: 159 NVTSFRNITQLSFQL--ISEPMFGDYWIVVKRNS---RKTVTHQFAVKRYVLPKFEV--T 211
V +I Q F + ISEP W + R S + QF VK+YVLP FEV T
Sbjct: 190 EVYMPSSIFQDDFVIPDISEP---GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKIT 246
Query: 212 VNAPQTVTISD--DEFQVDVCAKYTFGQPVQGKTQIR 246
P +T+ DE Q+D+ A+Y +G+PVQG +R
Sbjct: 247 PGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVR 283
>gi|38016947 complement component 5 preproprotein [Homo sapiens]
Length = 1676
Score = 134 bits (337), Expect = 6e-31
Identities = 146/557 (26%), Positives = 255/557 (45%), Gaps = 80/557 (14%)
Query: 719 VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQ 778
+R+ FPE+W+W++ V L F +PD++T WE G ++ + G ++ T +V +
Sbjct: 765 IRSYFPESWLWEVHLVPRR--KQLQFALPDSLTTWEIQGVGIS-NTGICVADTVKAKVFK 821
Query: 779 PFFIEIASPFSVVQNEQFDLIVNAFSY----LNTCVEISVQVEESQNYEANINTWKINGS 834
F+E+ P+SVV+ EQ L ++Y + CV++S + I+ S
Sbjct: 822 DVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSS 881
Query: 835 EVI--QAGGRKTNI--WTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNW--KDTVV 888
+ + + G +++ +T++P ++G NI E+ W K+ +V
Sbjct: 882 KCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLET-----------------WFGKEILV 924
Query: 889 KSFLVEPEGIEKERTQSFLICTEGAKAS----KQGVLDLPNDVVEG-------SARGFFT 937
K+ V PEG+++E + G + K+ +P D+V S +G
Sbjct: 925 KTLRVVPEGVKRESYSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGL-- 982
Query: 938 VVGDILG--LAMQNLVVL-QMPYGGGEQNAALLASDTYVLDYLKS--------TEQLTEE 986
+VG+IL L+ + + +L +P G E + YV YL++ ++ L E+
Sbjct: 983 LVGEILSAVLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEK 1042
Query: 987 VQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQNQKGSIWLSALTFKTLERMKKFVFIDEN 1046
+ K L G +S++N+D SYSV+ + S WL+A + L ++ K+V ++N
Sbjct: 1043 QKLKK--KLKEGMLSIMSYRNADYSYSVW--KGGSASTWLTAFALRVLGQVNKYVEQNQN 1098
Query: 1047 VQKQTLIWL-SSQQKTSGCFKNDGQLFNHAWEG-----GDEEDISLTAY-VVGM---FFE 1096
+L+WL + Q +G FK + Q +G E + LTA+ V+G+ F
Sbjct: 1099 SICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDI 1158
Query: 1097 AGLNSTFPALRNA-LFCLEAALDSGVTNGYNHAILAYAFALAGK-EKQVESLLQTLDQSA 1154
L AL A F LE L + T + AI AYA +L K Q S++ L + A
Sbjct: 1159 CPLVKIDTALIKADNFLLENTLPAQST--FTLAISAYALSLGDKTHPQFRSIVSALKREA 1216
Query: 1155 -TKLNNVIY--WERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIV 1211
K N IY W+ + K P+ + E + Y LL ++ K D+ Y + ++
Sbjct: 1217 LVKGNPPIYRFWKDNLQHKDSSVPN---TGTARMVETTAYALLTSLNLK--DINYVNPVI 1271
Query: 1212 QWLAQQMNSHGGFSSNQ 1228
+WL+++ GGF S Q
Sbjct: 1272 KWLSEEQRYGGGFYSTQ 1288
Score = 61.2 bits (147), Expect = 7e-09
Identities = 125/632 (19%), Positives = 248/632 (39%), Gaps = 69/632 (10%)
Query: 13 YVLLIPSVLQEGSLDKACAQLFNLTESVVLTVSL--------NYGEVQTKIFEENVTGEN 64
YV+ P + + G+ + Q++ TE+ T+S+ +Y + EN +
Sbjct: 23 YVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDKKFSYSSGHVHLSSENKFQNS 82
Query: 65 FFKCISFEVPQARSDPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQK 124
I + +P++++ + + + + + I +F+ TDKP Y P Q
Sbjct: 83 AILTIQPKQLPGGQNPVSYVYLEV--VSKHFSKSKRMPITYDNGFLFIHTDKPVYTPDQS 140
Query: 125 DVNGIAQFFLDTYTFTYPNI-TLKDPQNNRIFQWQNVTSFRNITQLSFQLISEPMFGDYW 183
+ D + T DP+ + + + + I+ F++ S P +G +
Sbjct: 141 VKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHIGIISFPDFKIPSNPRYGMWT 200
Query: 184 IVVK--RNSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTI---SDDEFQVDVCAKYTFGQP 238
I K + T T F VK YVLP F V++ P+ I + F++ + A+Y + +
Sbjct: 201 IKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIE-PEYNFIGYKNFKNFEITIKARYFYNKV 259
Query: 239 VQGKTQIRVCREYFSSSNCEKNDNEICEQFI--AQLENGCVSQIV---NTKVFQLYRSGL 293
V T+ V + + + + E+ + + L NG ++Q+ T V +L L
Sbjct: 260 V---TEADVYITFGIREDLKDDQKEMMQTAMQNTMLING-IAQVTFDSETAVKELSYYSL 315
Query: 294 ----FMTFHVAVIVTEFGTGNYCMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTL 349
++AV V E TG + + +E + +N F + GI Y +
Sbjct: 316 EDLNNKYLYIAVTVIE-STGGFSEE-AEIPGIKYVLSPYKLNLVATPLFLKPGIPYPIKV 373
Query: 350 KFSDP-----NNVPMVNKLLQLELNDEFIG-----NYTTDENGEAQFSID-TSDIFDPEF 398
+ D VP+ +++N E + T ++G A F ++ S + EF
Sbjct: 374 QVKDSLDQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASFVLNLPSGVTVLEF 433
Query: 399 NLKATYVRPKSCYLPSWLTPQYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVT-- 456
N+K P + + S + S+L I NH+ ++
Sbjct: 434 NVKTD--------APDLPEENQAREGYRAIAYSSLSQSYLYI-----DWTDNHKALLVGE 480
Query: 457 -VHYSLNSEAYEDDSNVKFFYLVSLSHDSGNFQHRISSSPIYTAWNGNFSFPLSISADLA 515
++ + ++ D + YL+ G H + A + + P ++ ++
Sbjct: 481 HLNIIVTPKSPYIDKITHYNYLIL---SKGKIIHFGTREKFSDASYQSINIP--VTQNMV 535
Query: 516 PAAVLFVY---TLHPSGEIVADSVRFQVDKCFKHKVNIKFSNEQGL--PGSNASLYLQAA 570
P++ L VY T + E+V+DSV +++ +++ + S + PG SL +
Sbjct: 536 PSSRLLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQTVSLNMATG 595
Query: 571 PVLFCALGAVDGNVLLLKSEQQLSAESVYNMV 602
+ AL AVD V ++ + E V+ +
Sbjct: 596 MDSWVALAAVDSAVYGVQRGAKKPLERVFQFL 627
>gi|239754277 PREDICTED: similar to Complement component 4A (Rodgers
blood group) [Homo sapiens]
Length = 270
Score = 60.8 bits (146), Expect = 9e-09
Identities = 55/157 (35%), Positives = 80/157 (50%), Gaps = 24/157 (15%)
Query: 105 SRENVVFVQTDKPTYKPGQKDVNGIAQFFLD------TYTFTYPNITLKDPQNNRIFQWQ 158
SR +F+QTD+P Y PGQ+ + F LD T T T + +++ R+ + +
Sbjct: 56 SRRGHLFLQTDQPIYNPGQRVRYRV--FALDQKMRPSTDTIT---VMVENSHGLRVRK-K 109
Query: 159 NVTSFRNITQLSFQL--ISEPMFGDYWIVVKRNS---RKTVTHQFAVKRYVLPKFEV--T 211
V +I Q F + ISEP W + R S + QF VK+YVLP FEV T
Sbjct: 110 EVYMPSSIFQDDFVIPDISEP---GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKIT 166
Query: 212 VNAPQTVTISD--DEFQVDVCAKYTFGQPVQGKTQIR 246
P +T+ DE Q+D+ A+Y +G+PVQG +R
Sbjct: 167 PGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVR 203
>gi|239758130 PREDICTED: similar to complement component 4B (Childo
blood group), partial [Homo sapiens]
Length = 666
Score = 53.5 bits (127), Expect = 1e-06
Identities = 73/326 (22%), Positives = 124/326 (38%), Gaps = 35/326 (10%)
Query: 1027 SALTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWEG---GDEED 1083
+A K L ++ V ++T WL SQQ+ G F++ + + + +G G++E
Sbjct: 1 TAFVLKVLSLAQEQVGGSREKLQETSNWLLSQQQADGSFQDLSPVIHRSMQGGLVGNDET 60
Query: 1084 ISLTAYV-------VGMFFEAGL----NSTFPALRNALFCLEAALDSGVTNGYNHAILAY 1132
++LTA+V + +F + G ++ A L +G+ + AI AY
Sbjct: 61 VALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAY 120
Query: 1133 AFALAGKEKQVESLL-QTLDQSATKLNNVIYW-----------ERERKPKTEEFPSFIPW 1180
A L + + L A + + +YW P+ P +P
Sbjct: 121 ALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDP--MPQ 178
Query: 1181 APSAQTEKSCYVLLAVISRKIPDLTYASKIVQWLAQQMNSHGGFSSNQVINVGL-ILIAI 1239
AP+ E + Y LL ++ + A + WL +Q + GGF S Q + L L A
Sbjct: 179 APALWIETTAYALLHLLLHE-GKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAY 237
Query: 1240 CGEEGLFSKNQNTVTFSSEG-----SSEIQFNGHNRLLVQRSEVTQAPGQYTVDVEGRGC 1294
+ VT SS G S +Q N ++ + V V G
Sbjct: 238 WIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSK 297
Query: 1295 TFIQATLKYNVLLPKKASGFSLSLEI 1320
++ YNVL K + L +E+
Sbjct: 298 GTLKVLRTYNVLDMKNTTCQDLQIEV 323
>gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens]
Length = 95
Score = 47.4 bits (111), Expect = 1e-04
Identities = 22/28 (78%), Positives = 25/28 (89%)
Query: 1346 MVVIDVKMLSGFTPTMSSIEEVNNRSLI 1373
MVVIDVKMLSGFTPTMSSIEE+ N+ +
Sbjct: 1 MVVIDVKMLSGFTPTMSSIEELENKGQV 28
>gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sapiens]
Length = 95
Score = 47.4 bits (111), Expect = 1e-04
Identities = 22/28 (78%), Positives = 25/28 (89%)
Query: 1346 MVVIDVKMLSGFTPTMSSIEEVNNRSLI 1373
MVVIDVKMLSGFTPTMSSIEE+ N+ +
Sbjct: 1 MVVIDVKMLSGFTPTMSSIEELENKGQV 28
>gi|169214179 PREDICTED: similar to complement component 3 [Homo
sapiens]
Length = 390
Score = 32.0 bits (71), Expect = 4.3
Identities = 29/142 (20%), Positives = 59/142 (41%), Gaps = 25/142 (17%)
Query: 1275 RSEVTQAPGQYTVDVEGRGCTFIQATLKYNVLLPKKASGFSLSLEIV----------KNY 1324
RSE T+ +TV EG+G + Y+ + + L++
Sbjct: 47 RSEETKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQD 106
Query: 1325 SLTVFDLTVNLKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEEVNN----------RSLIF 1374
+ L + +Y G ++ ++M ++D+ M++GF P ++++ N F
Sbjct: 107 AKNTMILEICTRYRGDQD-ATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAF 165
Query: 1375 HHKDSYIEYKDKI----NTCLA 1392
+++ I Y DK+ + CLA
Sbjct: 166 SDRNTLIIYLDKVSHSEDDCLA 187
>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
Length = 789
Score = 32.0 bits (71), Expect = 4.3
Identities = 18/51 (35%), Positives = 30/51 (58%), Gaps = 8/51 (15%)
Query: 348 TLKFSDPNNVPMVNKLLQLELNDEFIGNYTTDENGEAQFSI---DTSDIFD 395
T +F+ P +VP+ L +++ ND +G EN E ++SI D +D+FD
Sbjct: 272 TYQFNSPESVPLGTHLGRIKANDPDVG-----ENAEMEYSIAEGDGADMFD 317
>gi|22550104 ubiquitin specific protease 32 [Homo sapiens]
Length = 1604
Score = 31.6 bits (70), Expect = 5.6
Identities = 58/231 (25%), Positives = 85/231 (36%), Gaps = 48/231 (20%)
Query: 457 VHYSLNSEAYEDDS--NVKFFYLVSLSHDSGNFQHRISSSPIYT-AWNGNFSFPLSISAD 513
V Y N E S N + + +H + RI SS Y FS +S +++
Sbjct: 411 VKYDANPVVIEPSSVLNGGKYSFGTAAHPMEQVEDRIGSSLSYVNTTEEKFSDNISTASE 470
Query: 514 LAPAAVL-FVYTLHPSGEIVADSVRFQVDKCFKHKVNIKFSNEQGLPGSNASLYLQAAPV 572
+ A F+Y+ P ++ CF + N +N Q L G+N ++ L P
Sbjct: 471 ASETAGSGFLYSATPGADV-----------CFARQHNTSDNNNQCLLGANGNILLHLNPQ 519
Query: 573 LFCALGAVDGNVLL----------------LKSEQQLSAESVYNMVPSIEPYG---YFYH 613
GA+D L+ LK QL Y MVP EP Y ++
Sbjct: 520 ---KPGAIDNQPLVTQEPVKATSLTLEGGRLKRTPQLIHGRDYEMVP--EPVWRALYHWY 574
Query: 614 GLNL-------DDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMG 657
G NL + K D IP+ ++F L + NI NMG
Sbjct: 575 GANLALPRPVIKNSKTD--IPELELFPRYLLFLRQQPATRTQQSNIWVNMG 623
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,942,008
Number of Sequences: 37866
Number of extensions: 2165685
Number of successful extensions: 4453
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 4242
Number of HSP's gapped (non-prelim): 62
length of query: 1394
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1279
effective length of database: 13,892,928
effective search space: 17769054912
effective search space used: 17769054912
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.