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Search of human proteins with 239743797
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239743797 PREDICTED: similar to cell recognition molecule
CASPR3 [Homo sapiens]
(944 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239743797 PREDICTED: similar to cell recognition molecule CAS... 1954 0.0
gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1... 1201 0.0
gi|47519929 cell recognition molecule CASPR3 [Homo sapiens] 1196 0.0
gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2... 746 0.0
gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap... 740 0.0
gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap... 740 0.0
gi|18640734 contactin associated protein-like 5 [Homo sapiens] 548 e-156
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi... 499 e-141
gi|4505463 contactin associated protein 1 precursor [Homo sapiens] 344 3e-94
gi|169184330 PREDICTED: novel protein similar to contactin assoc... 290 6e-78
gi|239758135 PREDICTED: similar to cell recognition molecule CAS... 272 9e-73
gi|239752499 PREDICTED: similar to cell recognition molecule Cas... 146 1e-34
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens] 114 3e-25
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens] 114 4e-25
gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens] 112 2e-24
gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens] 111 3e-24
gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens] 110 5e-24
gi|33469931 EGF-like, fibronectin type III and laminin G domains... 74 6e-13
gi|33469929 EGF-like, fibronectin type III and laminin G domains... 74 6e-13
gi|33469935 EGF-like, fibronectin type III and laminin G domains... 74 8e-13
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 73 1e-12
gi|54873613 agrin [Homo sapiens] 69 3e-11
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 68 5e-11
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 57 1e-07
gi|11321571 slit homolog 3 [Homo sapiens] 56 2e-07
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 53 1e-06
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 53 1e-06
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo... 53 1e-06
gi|33469937 EGF-like, fibronectin type III and laminin G domains... 53 2e-06
gi|188528675 slit homolog 1 [Homo sapiens] 52 2e-06
>gi|239743797 PREDICTED: similar to cell recognition molecule CASPR3
[Homo sapiens]
Length = 944
Score = 1954 bits (5063), Expect = 0.0
Identities = 944/944 (100%), Positives = 944/944 (100%)
Query: 1 MCWPFFVEVLRTTLYPSSPSVTLPARVSPFLPECHPAPLPADFQTGFSWVQPLRWVNSGV 60
MCWPFFVEVLRTTLYPSSPSVTLPARVSPFLPECHPAPLPADFQTGFSWVQPLRWVNSGV
Sbjct: 1 MCWPFFVEVLRTTLYPSSPSVTLPARVSPFLPECHPAPLPADFQTGFSWVQPLRWVNSGV 60
Query: 61 IKPGVLHLQAEADGAVFGASPCTTAAPPRWERGTEEAAGITGGERQAELGRPSRSLLDSR 120
IKPGVLHLQAEADGAVFGASPCTTAAPPRWERGTEEAAGITGGERQAELGRPSRSLLDSR
Sbjct: 61 IKPGVLHLQAEADGAVFGASPCTTAAPPRWERGTEEAAGITGGERQAELGRPSRSLLDSR 120
Query: 121 CCRPPPAPSVRDAPEPAASVPGAAPRGPERSRKLRCESAGPTSETQLGPGAAWREGLQRR 180
CCRPPPAPSVRDAPEPAASVPGAAPRGPERSRKLRCESAGPTSETQLGPGAAWREGLQRR
Sbjct: 121 CCRPPPAPSVRDAPEPAASVPGAAPRGPERSRKLRCESAGPTSETQLGPGAAWREGLQRR 180
Query: 181 GRLLVRCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGI 240
GRLLVRCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGI
Sbjct: 181 GRLLVRCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGI 240
Query: 241 TDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYI 300
TDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYI
Sbjct: 241 TDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYI 300
Query: 301 DADGSGPLGPFLVYCNMTDRSALPLAAGLCRPVMPLLCPFLLSRLRVDGGAARWPRRGDP 360
DADGSGPLGPFLVYCNMTDRSALPLAAGLCRPVMPLLCPFLLSRLRVDGGAARWPRRGDP
Sbjct: 301 DADGSGPLGPFLVYCNMTDRSALPLAAGLCRPVMPLLCPFLLSRLRVDGGAARWPRRGDP 360
Query: 361 PRCPQWAPALGCVLRVRSGRGAAAGRGEPGGALRAAAGSALRDSAAPGLTSLMVKSVTFK 420
PRCPQWAPALGCVLRVRSGRGAAAGRGEPGGALRAAAGSALRDSAAPGLTSLMVKSVTFK
Sbjct: 361 PRCPQWAPALGCVLRVRSGRGAAAGRGEPGGALRAAAGSALRDSAAPGLTSLMVKSVTFK 420
Query: 421 VAFREEYGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWT 480
VAFREEYGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWT
Sbjct: 421 VAFREEYGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWT 480
Query: 481 SDTIVLSQKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFP 540
SDTIVLSQKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFP
Sbjct: 481 SDTIVLSQKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFP 540
Query: 541 AFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQS 600
AFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQS
Sbjct: 541 AFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQS 600
Query: 601 PTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRG 660
PTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRG
Sbjct: 601 PTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRG 660
Query: 661 FLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCA 720
FLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCA
Sbjct: 661 FLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCA 720
Query: 721 FSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFR 780
FSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFR
Sbjct: 721 FSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFR 780
Query: 781 TTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVK 840
TTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVK
Sbjct: 781 TTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVK 840
Query: 841 INREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLGRSGPVDEGEPLVNADRRDS 900
INREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLGRSGPVDEGEPLVNADRRDS
Sbjct: 841 INREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLGRSGPVDEGEPLVNADRRDS 900
Query: 901 AVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC 944
AVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC
Sbjct: 901 AVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC 944
>gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1
[Homo sapiens]
Length = 1288
Score = 1201 bits (3106), Expect = 0.0
Identities = 602/698 (86%), Positives = 613/698 (87%), Gaps = 40/698 (5%)
Query: 187 CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 246
CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP
Sbjct: 494 CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 553
Query: 247 SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 306
SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG
Sbjct: 554 SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 613
Query: 307 PLGPFLVYCNMTDRSALPLAAGLCRPVMPLLCPFLLSRLRVDGGAARWPRRGDPPRCPQW 366
PLGPFLVYCNMT SA + GG RG P P
Sbjct: 614 PLGPFLVYCNMTADSAWTVVR--------------------HGGPDAVTLRGAPSGHPLS 653
Query: 367 APALGCVLRVRSGRGAAAGRGEPGGALRAAAGSALRDSAAPGLTSLMVKSVTFKVAFREE 426
A + AAG G+ LRAA A R L ++ T + +
Sbjct: 654 AVSFAY----------AAGAGQ----LRAAVNLAERCEQR-----LALRCGTARRPDSRD 694
Query: 427 YGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVL 486
GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAG+NEWTSDTIVL
Sbjct: 695 -GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVL 753
Query: 487 SQKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGEL 546
SQKEHLPVTQIVMTD GQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGEL
Sbjct: 754 SQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGEL 813
Query: 547 TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 606
TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND
Sbjct: 814 TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 873
Query: 607 NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIR 666
NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIR
Sbjct: 874 NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIR 933
Query: 667 SLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDG 726
SLQLNGVALDLEERATV PGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDG
Sbjct: 934 SLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDG 993
Query: 727 PFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPS 786
PFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSL+RDVTLTREMITLSFRTTR+PS
Sbjct: 994 PFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPS 1053
Query: 787 LLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEA 846
LLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEA
Sbjct: 1054 LLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEA 1113
Query: 847 VVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLGRSG 884
VVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVL +G
Sbjct: 1114 VVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAG 1151
Score = 123 bits (308), Expect = 9e-28
Identities = 62/64 (96%), Positives = 63/64 (98%)
Query: 881 GRSGPVDEGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSK 940
GRSGPVDEGEPLVNADRRDSAV+GGVIAV IFILLCITAIAIRIYQQRKLRKENESKVSK
Sbjct: 1225 GRSGPVDEGEPLVNADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSK 1284
Query: 941 KEEC 944
KEEC
Sbjct: 1285 KEEC 1288
Score = 48.1 bits (113), Expect = 4e-05
Identities = 59/261 (22%), Positives = 96/261 (36%), Gaps = 24/261 (9%)
Query: 490 EHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTAD 549
E+L + +T+ + H +G + + +F + SYL P GE
Sbjct: 334 ENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVS 393
Query: 550 VCFFFKTTVSSG--VFME-NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 606
V F F+T +G +F E G F+ +++ F G P VT + ND
Sbjct: 394 VTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSL-FQAGQSPRNVTAGAG--LND 450
Query: 607 NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRG------ 660
QWH V ++ VD +QP A V + + GG G
Sbjct: 451 GQWHSVSFSAKWSHMNVVVDD-DTAVQPLVA---VLIDSGDTYYFGGCLGNSSGSGCKSP 506
Query: 661 ---FLGCIRSLQLNGVALD--LEERATVMPGVE---PGCAGHCSTYGHLCRNGGRCREKR 712
F GC+R + + A+D L ++ + + C C +GG C +
Sbjct: 507 LGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSW 566
Query: 713 RGVTCDCAFSAYDGPFCSNEI 733
+CDC + Y G C + +
Sbjct: 567 DTFSCDCLGTGYTGETCHSSL 587
Score = 33.5 bits (75), Expect = 0.96
Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 16/133 (12%)
Query: 554 FKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTP-----FNDN 607
FK S+G+ + G + I +EL ++ F + GN T+ T +D
Sbjct: 212 FKAMQSNGILLHREGQHGNHITLEL-IKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270
Query: 608 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGT-------ATRQRG 660
WH V E + VD+ Q A D L LN ++ GG A ++
Sbjct: 271 HWHSVLIELLDTQVNFTVDKHTHHFQ-AKGDSS-NLDLNFEISFGGILSPGRSRAFTRKS 328
Query: 661 FLGCIRSLQLNGV 673
F GC+ +L NGV
Sbjct: 329 FHGCLENLYYNGV 341
>gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]
Length = 1288
Score = 1196 bits (3094), Expect = 0.0
Identities = 599/698 (85%), Positives = 612/698 (87%), Gaps = 40/698 (5%)
Query: 187 CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 246
CL NSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP
Sbjct: 494 CLDNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 553
Query: 247 SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 306
SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG
Sbjct: 554 SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 613
Query: 307 PLGPFLVYCNMTDRSALPLAAGLCRPVMPLLCPFLLSRLRVDGGAARWPRRGDPPRCPQW 366
PLGPFLVYCNMT +A + GG RG P P+
Sbjct: 614 PLGPFLVYCNMTADAAWTVVQ--------------------HGGPDAVTLRGAPSGHPRS 653
Query: 367 APALGCVLRVRSGRGAAAGRGEPGGALRAAAGSALRDSAAPGLTSLMVKSVTFKVAFREE 426
A + AAG G+ LR+A A R L ++ T + +
Sbjct: 654 AVSFAY----------AAGAGQ----LRSAVNLAERCEQR-----LALRCGTARRPDSRD 694
Query: 427 YGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVL 486
GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVL
Sbjct: 695 -GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVL 753
Query: 487 SQKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGEL 546
SQKEHLPVTQIVMTDAG+PHSEA YTLGPLLCRGD+SFWNSASFNTETSYLHFPAFHGEL
Sbjct: 754 SQKEHLPVTQIVMTDAGRPHSEAAYTLGPLLCRGDQSFWNSASFNTETSYLHFPAFHGEL 813
Query: 547 TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 606
TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND
Sbjct: 814 TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 873
Query: 607 NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIR 666
NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIR
Sbjct: 874 NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIR 933
Query: 667 SLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDG 726
SLQLNGVALDLEERATV PGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDG
Sbjct: 934 SLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDG 993
Query: 727 PFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPS 786
PFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPS
Sbjct: 994 PFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPS 1053
Query: 787 LLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEA 846
LLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEA
Sbjct: 1054 LLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEA 1113
Query: 847 VVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLGRSG 884
VVMVEVNQS KKQVILSSGTEFNAVKSLILGKVL +G
Sbjct: 1114 VVMVEVNQSTKKQVILSSGTEFNAVKSLILGKVLEAAG 1151
Score = 122 bits (307), Expect = 1e-27
Identities = 62/64 (96%), Positives = 62/64 (96%)
Query: 881 GRSGPVDEGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSK 940
GRSGP DEGEPLVNADRRDSAVIGGVIAV IFILLCITAIAIRIYQQRKLRKENESKVSK
Sbjct: 1225 GRSGPADEGEPLVNADRRDSAVIGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSK 1284
Query: 941 KEEC 944
KEEC
Sbjct: 1285 KEEC 1288
Score = 47.8 bits (112), Expect = 5e-05
Identities = 59/261 (22%), Positives = 96/261 (36%), Gaps = 24/261 (9%)
Query: 490 EHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTAD 549
E+L + +T+ + H +G + + +F + SYL P GE
Sbjct: 334 ENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVS 393
Query: 550 VCFFFKTTVSSG--VFME-NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 606
V F F+T +G +F E G F+ +++ F G P VT + ND
Sbjct: 394 VTFQFRTWNRAGHLLFGELRRGSGSFVLFLKDGKLKLSL-FQPGQSPRNVTAGAG--LND 450
Query: 607 NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRG------ 660
QWH V ++ VD +QP A V + + GG G
Sbjct: 451 GQWHSVSFSAKWSHMNVVVDD-DTAVQPLVA---VLIDSGDTYYFGGCLDNSSGSGCKSP 506
Query: 661 ---FLGCIRSLQLNGVALD--LEERATVMPGVE---PGCAGHCSTYGHLCRNGGRCREKR 712
F GC+R + + A+D L ++ + + C C +GG C +
Sbjct: 507 LGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSW 566
Query: 713 RGVTCDCAFSAYDGPFCSNEI 733
+CDC + Y G C + +
Sbjct: 567 DTFSCDCLGTGYTGETCHSSL 587
Score = 36.2 bits (82), Expect = 0.15
Identities = 35/133 (26%), Positives = 54/133 (40%), Gaps = 16/133 (12%)
Query: 554 FKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTP-----FNDN 607
FK S+G+ + G + I +EL ++ F + GN T+ T +D
Sbjct: 212 FKAMQSNGILLHREGQHGNHITLEL-IKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270
Query: 608 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTAT-------RQRG 660
WH V E + VD+ Q + L LN ++ GG T R++
Sbjct: 271 HWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSY--LDLNFEISFGGIPTPGRSRAFRRKS 328
Query: 661 FLGCIRSLQLNGV 673
F GC+ +L NGV
Sbjct: 329 FHGCLENLYYNGV 341
>gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2
[Homo sapiens]
Length = 1207
Score = 746 bits (1926), Expect = 0.0
Identities = 374/465 (80%), Positives = 383/465 (82%), Gaps = 41/465 (8%)
Query: 187 CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 246
CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP
Sbjct: 494 CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 553
Query: 247 SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 306
SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG
Sbjct: 554 SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 613
Query: 307 PLGPFLVYCNMTDRSALPLAAGLCRPVMPLLCPFLLSRLRVDGGAARWPRRGDPPRCPQW 366
PLGPFLVYCNMTD + + GG RG P P
Sbjct: 614 PLGPFLVYCNMTDSAWTVVR---------------------HGGPDAVTLRGAPSGHPLS 652
Query: 367 APALGCVLRVRSGRGAAAGRGEPGGALRAAAGSALRDSAAPGLTSLMVKSVTFKVAFREE 426
A + AAG G+ LRAA A R L ++ T + +
Sbjct: 653 AVSFAY----------AAGAGQ----LRAAVNLAERCEQR-----LALRCGTARRPDSRD 693
Query: 427 YGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVL 486
GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAG+NEWTSDTIVL
Sbjct: 694 -GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVL 752
Query: 487 SQKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGEL 546
SQKEHLPVTQIVMTD GQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGEL
Sbjct: 753 SQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGEL 812
Query: 547 TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 606
TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND
Sbjct: 813 TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 872
Query: 607 NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFI 651
NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFI
Sbjct: 873 NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFI 917
Score = 287 bits (735), Expect = 3e-77
Identities = 148/153 (96%), Positives = 151/153 (98%)
Query: 732 EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYV 791
EISAYFATGSSMTYHFQEHYTLSENSSSLVSSL+RDVTLTREMITLSFRTTR+PSLLLYV
Sbjct: 918 EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV 977
Query: 792 SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 851
SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE
Sbjct: 978 SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 1037
Query: 852 VNQSAKKQVILSSGTEFNAVKSLILGKVLGRSG 884
VNQSAKKQVILSSGTEFNAVKSLILGKVL +G
Sbjct: 1038 VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAG 1070
Score = 123 bits (308), Expect = 9e-28
Identities = 62/64 (96%), Positives = 63/64 (98%)
Query: 881 GRSGPVDEGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSK 940
GRSGPVDEGEPLVNADRRDSAV+GGVIAV IFILLCITAIAIRIYQQRKLRKENESKVSK
Sbjct: 1144 GRSGPVDEGEPLVNADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSK 1203
Query: 941 KEEC 944
KEEC
Sbjct: 1204 KEEC 1207
Score = 48.1 bits (113), Expect = 4e-05
Identities = 59/261 (22%), Positives = 96/261 (36%), Gaps = 24/261 (9%)
Query: 490 EHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTAD 549
E+L + +T+ + H +G + + +F + SYL P GE
Sbjct: 334 ENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVS 393
Query: 550 VCFFFKTTVSSG--VFME-NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 606
V F F+T +G +F E G F+ +++ F G P VT + ND
Sbjct: 394 VTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSL-FQAGQSPRNVTAGAG--LND 450
Query: 607 NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRG------ 660
QWH V ++ VD +QP A V + + GG G
Sbjct: 451 GQWHSVSFSAKWSHMNVVVDD-DTAVQPLVA---VLIDSGDTYYFGGCLGNSSGSGCKSP 506
Query: 661 ---FLGCIRSLQLNGVALD--LEERATVMPGVE---PGCAGHCSTYGHLCRNGGRCREKR 712
F GC+R + + A+D L ++ + + C C +GG C +
Sbjct: 507 LGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSW 566
Query: 713 RGVTCDCAFSAYDGPFCSNEI 733
+CDC + Y G C + +
Sbjct: 567 DTFSCDCLGTGYTGETCHSSL 587
Score = 33.5 bits (75), Expect = 0.96
Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 16/133 (12%)
Query: 554 FKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTP-----FNDN 607
FK S+G+ + G + I +EL ++ F + GN T+ T +D
Sbjct: 212 FKAMQSNGILLHREGQHGNHITLEL-IKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270
Query: 608 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGT-------ATRQRG 660
WH V E + VD+ Q A D L LN ++ GG A ++
Sbjct: 271 HWHSVLIELLDTQVNFTVDKHTHHFQ-AKGDSS-NLDLNFEISFGGILSPGRSRAFTRKS 328
Query: 661 FLGCIRSLQLNGV 673
F GC+ +L NGV
Sbjct: 329 FHGCLENLYYNGV 341
>gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sapiens]
Length = 1235
Score = 740 bits (1911), Expect = 0.0
Identities = 353/468 (75%), Positives = 400/468 (85%), Gaps = 1/468 (0%)
Query: 428 GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVLS 487
GTPLSWWVGRTNET T WGGS PD QKCTCGLEGNCIDSQYYCNCDA RNEWT+DT +L+
Sbjct: 622 GTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWTNDTGLLA 681
Query: 488 QKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELT 547
KEHLPVT+IV+TD G+ HSEA Y LGPLLC+GD+SFWNSASF+TE SYLHFP FHGEL+
Sbjct: 682 YKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELS 741
Query: 548 ADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDN 607
ADV FFFKTT SSGVF+ENLGI DFIRIELR+PT VTFSFDVGNGP E++VQSPT FNDN
Sbjct: 742 ADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDN 801
Query: 608 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRS 667
QWHHVR ERN+K ASLQVDQL K QPAPADGHV LQLNSQLF+GGTATRQRGFLGCIRS
Sbjct: 802 QWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRGFLGCIRS 861
Query: 668 LQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGP 727
LQLNG+ LDLEERA V P V+PGC GHCS+YG LCRNGG+CRE+ G CDC FSAY GP
Sbjct: 862 LQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGP 921
Query: 728 FCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSL 787
FCSNEISAYF +GSS+ Y+FQE+Y LS+NSSS +S H D+ L+REMI SFRTTRTPSL
Sbjct: 922 FCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSL 981
Query: 788 LLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAV 847
LL+VSSFY+EYLSVI+A NGSLQIRYKL+++Q PD FDFKNMADGQLH + INREE V
Sbjct: 982 LLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGV 1041
Query: 848 VMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLGRSGPVDEGEPLVNA 895
V +E++ + ++QV LSSGTEF+AVKSL+LG++L S VD+ L A
Sbjct: 1042 VFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHS-DVDQDTALAGA 1088
Score = 227 bits (579), Expect = 3e-59
Identities = 100/133 (75%), Positives = 113/133 (84%)
Query: 187 CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 246
C S GS CKSPLGGFQGC+RLI+I K VD I VQQG+LG+F DLQIDSCGI+DRCLP
Sbjct: 423 CPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLP 482
Query: 247 SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 306
+YCEHGGECSQSW TF C+C TGY G TCH+S+YEQSCEA+KHRGN SG YYID+DGSG
Sbjct: 483 NYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSG 542
Query: 307 PLGPFLVYCNMTD 319
PL PFL+YCNMT+
Sbjct: 543 PLEPFLLYCNMTE 555
Score = 79.0 bits (193), Expect = 2e-14
Identities = 39/58 (67%), Positives = 49/58 (84%)
Query: 883 SGPVDEGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSK 940
SG +D+ EPL NA + DSAVIGG+IAV IFILLCITAIA+RIYQQ++L K +E+K S+
Sbjct: 1150 SGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSE 1207
Score = 67.8 bits (164), Expect = 5e-11
Identities = 91/374 (24%), Positives = 138/374 (36%), Gaps = 77/374 (20%)
Query: 506 HSEADYTLGPLLCRGDKSFWNS------ASFNTETSYLHFPAFHGELTADVCFFFKTTVS 559
H+ ++ L L G+ SF S +F + SYL P F GE F F+T
Sbjct: 271 HARGEFNLMNLDYEGNVSFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNK 330
Query: 560 SGV--FMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERN 617
+G+ F E I+ I + L + + G P ++T + ND QWH V
Sbjct: 331 AGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDIT--AGVELNDGQWHSVSLSAK 388
Query: 618 VKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQ---------RGFLGCIRSL 668
S+ VD Q AP G ++ + GG + GF GC+R +
Sbjct: 389 KNHLSVAVDG--QMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPLGGFQGCMRLI 446
Query: 669 QLNGVALDLEERATVMPGVEPGCAGHCSTYG------------HLCRNGGRCREKRRGVT 716
++G +DL V+ G G+ S + C +GG C +
Sbjct: 447 SISGKVVDLIS-------VQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWSTFH 499
Query: 717 CDCAFSAYDGPFCSNEI-----SAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLT 771
C+C + Y G C N I AY G++ + +Y S+ S L
Sbjct: 500 CNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGF----YYIDSDGSGPL----------- 544
Query: 772 REMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNM 831
LLY + E I+ +NGS R + +NP A F++ +
Sbjct: 545 -------------EPFLLYCN--MTETAWTIIQHNGSDLTRVRNTNPENPYAGFFEY--V 587
Query: 832 ADGQLHQVKINREE 845
A + Q INR E
Sbjct: 588 ASMEQLQATINRAE 601
Score = 35.0 bits (79), Expect = 0.33
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 18/76 (23%)
Query: 223 QQGALGSFRDLQIDS--------CGITDRCLP-------SY---CEHGGECSQSWDTFSC 264
Q+G LG R LQ++ +T P SY C +GG+C + F C
Sbjct: 852 QRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFC 911
Query: 265 DCLGTGYTGETCHSSL 280
DC + YTG C + +
Sbjct: 912 DCTFSAYTGPFCSNEI 927
>gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sapiens]
Length = 1308
Score = 740 bits (1911), Expect = 0.0
Identities = 353/468 (75%), Positives = 400/468 (85%), Gaps = 1/468 (0%)
Query: 428 GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVLS 487
GTPLSWWVGRTNET T WGGS PD QKCTCGLEGNCIDSQYYCNCDA RNEWT+DT +L+
Sbjct: 695 GTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWTNDTGLLA 754
Query: 488 QKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELT 547
KEHLPVT+IV+TD G+ HSEA Y LGPLLC+GD+SFWNSASF+TE SYLHFP FHGEL+
Sbjct: 755 YKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELS 814
Query: 548 ADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDN 607
ADV FFFKTT SSGVF+ENLGI DFIRIELR+PT VTFSFDVGNGP E++VQSPT FNDN
Sbjct: 815 ADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDN 874
Query: 608 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRS 667
QWHHVR ERN+K ASLQVDQL K QPAPADGHV LQLNSQLF+GGTATRQRGFLGCIRS
Sbjct: 875 QWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRGFLGCIRS 934
Query: 668 LQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGP 727
LQLNG+ LDLEERA V P V+PGC GHCS+YG LCRNGG+CRE+ G CDC FSAY GP
Sbjct: 935 LQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGP 994
Query: 728 FCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSL 787
FCSNEISAYF +GSS+ Y+FQE+Y LS+NSSS +S H D+ L+REMI SFRTTRTPSL
Sbjct: 995 FCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSL 1054
Query: 788 LLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAV 847
LL+VSSFY+EYLSVI+A NGSLQIRYKL+++Q PD FDFKNMADGQLH + INREE V
Sbjct: 1055 LLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGV 1114
Query: 848 VMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLGRSGPVDEGEPLVNA 895
V +E++ + ++QV LSSGTEF+AVKSL+LG++L S VD+ L A
Sbjct: 1115 VFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHS-DVDQDTALAGA 1161
Score = 227 bits (579), Expect = 3e-59
Identities = 100/133 (75%), Positives = 113/133 (84%)
Query: 187 CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 246
C S GS CKSPLGGFQGC+RLI+I K VD I VQQG+LG+F DLQIDSCGI+DRCLP
Sbjct: 496 CPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLP 555
Query: 247 SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 306
+YCEHGGECSQSW TF C+C TGY G TCH+S+YEQSCEA+KHRGN SG YYID+DGSG
Sbjct: 556 NYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSG 615
Query: 307 PLGPFLVYCNMTD 319
PL PFL+YCNMT+
Sbjct: 616 PLEPFLLYCNMTE 628
Score = 79.0 bits (193), Expect = 2e-14
Identities = 39/58 (67%), Positives = 49/58 (84%)
Query: 883 SGPVDEGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSK 940
SG +D+ EPL NA + DSAVIGG+IAV IFILLCITAIA+RIYQQ++L K +E+K S+
Sbjct: 1223 SGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSE 1280
Score = 65.1 bits (157), Expect = 3e-10
Identities = 84/345 (24%), Positives = 127/345 (36%), Gaps = 71/345 (20%)
Query: 529 SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGV--FMENLGITDFIRIELRAPTEVTFS 586
+F + SYL P F GE F F+T +G+ F E I+ I + L +
Sbjct: 373 TFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNL 432
Query: 587 FDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLN 646
+ G P ++T + ND QWH V S+ VD Q AP G ++
Sbjct: 433 YQPGKLPSDIT--AGVELNDGQWHSVSLSAKKNHLSVAVDG--QMASAAPLLGPEQIYSG 488
Query: 647 SQLFIGGTATRQ---------RGFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCST 697
+ GG + GF GC+R + ++G +DL V+ G G+ S
Sbjct: 489 GTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLIS-------VQQGSLGNFSD 541
Query: 698 YG------------HLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEI-----SAYFATG 740
+ C +GG C + C+C + Y G C N I AY G
Sbjct: 542 LQIDSCGISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRG 601
Query: 741 SSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLS 800
++ + +Y S+ S L LLY + E
Sbjct: 602 NTSGF----YYIDSDGSGPL------------------------EPFLLYCN--MTETAW 631
Query: 801 VILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREE 845
I+ +NGS R + +NP A F++ +A + Q INR E
Sbjct: 632 TIIQHNGSDLTRVRNTNPENPYAGFFEY--VASMEQLQATINRAE 674
Score = 35.0 bits (79), Expect = 0.33
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 18/76 (23%)
Query: 223 QQGALGSFRDLQIDS--------CGITDRCLP-------SY---CEHGGECSQSWDTFSC 264
Q+G LG R LQ++ +T P SY C +GG+C + F C
Sbjct: 925 QRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFC 984
Query: 265 DCLGTGYTGETCHSSL 280
DC + YTG C + +
Sbjct: 985 DCTFSAYTGPFCSNEI 1000
Score = 31.2 bits (69), Expect = 4.8
Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 16/133 (12%)
Query: 554 FKTTVSSGVFMENLGIT-DFIRIELR-APTEVTFSFDVGNGPCEVTVQSPTP---FNDNQ 608
FKT S G+ + G D I ++LR A + + P T+ + T +D
Sbjct: 212 FKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDDQH 271
Query: 609 WHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQ-LNSQLFIGG-------TATRQRG 660
WH V +R K + VD+ A G L L+ ++ GG + R
Sbjct: 272 WHSVLIQRLGKQVNFTVDEHRHHFH---ARGEFNLMNLDYEISFGGIPAPGKSVSFPHRN 328
Query: 661 FLGCIRSLQLNGV 673
F GC+ +L NGV
Sbjct: 329 FHGCLENLYYNGV 341
>gi|18640734 contactin associated protein-like 5 [Homo sapiens]
Length = 1306
Score = 548 bits (1413), Expect = e-156
Identities = 252/457 (55%), Positives = 333/457 (72%), Gaps = 1/457 (0%)
Query: 428 GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVLS 487
GTP +WW+GR+NE H WGGS P Q+C CGL+ +C+D Q++CNCDA ++EWT+DT LS
Sbjct: 693 GTPFTWWIGRSNERHPYWGGSPPGVQQCECGLDESCLDIQHFCNCDADKDEWTNDTGFLS 752
Query: 488 QKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELT 547
K+HLPVTQIV+TD + +SEA + +GPL C GD+ FWN+ SF TE SYLHFP FH E +
Sbjct: 753 FKDHLPVTQIVITDTDRSNSEAAWRIGPLRCYGDRRFWNAVSFYTEASYLHFPTFHAEFS 812
Query: 548 ADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDN 607
AD+ FFFKTT SGVF+ENLGI DFIR+E+ +P+E+TF+ DVGNGP E+ VQSP+ NDN
Sbjct: 813 ADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPSLLNDN 872
Query: 608 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRS 667
QWH+VRAERN+K SLQVD LP+ + +GH RLQLNSQLF+GGT++RQ+GFLGCIRS
Sbjct: 873 QWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRS 932
Query: 668 LQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGP 727
L LNG +DLEERA V GV PGC GHCS+YG +C NGG+C EK G CDC S Y+GP
Sbjct: 933 LHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSICHNGGKCVEKHNGYLCDCTNSPYEGP 992
Query: 728 FCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSL 787
FC E+SA F G+S+TY FQE Y +++N S S+++ D ++E I LSF TT+ PSL
Sbjct: 993 FCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYTDSAPSKENIALSFVTTQAPSL 1052
Query: 788 LLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAV 847
LL+++S ++++ V+L NGSLQ+RY L++ + FT D N A+ ++H +KINRE
Sbjct: 1053 LLFINSSSQDFVVVLLCKNGSLQVRYHLNKEET-HVFTIDADNFANRRMHHLKINREGRE 1111
Query: 848 VMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLGRSG 884
+ ++++Q + S EF ++SL LGKV G
Sbjct: 1112 LTIQMDQQLRLSYNFSPEVEFRVIRSLTLGKVTENLG 1148
Score = 192 bits (487), Expect = 2e-48
Identities = 84/151 (55%), Positives = 106/151 (70%)
Query: 169 PGAAWREGLQRRGRLLVRCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALG 228
P + W + C N + S C +P+ FQGC+RLI I ++ D I VQQG+LG
Sbjct: 475 PDSTWVQIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLG 534
Query: 229 SFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAH 288
+F DL ID C I DRCLP+YCEHGG CSQSW TF C+C T YTG TCH+S+YEQSCE +
Sbjct: 535 NFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVY 594
Query: 289 KHRGNPSGLYYIDADGSGPLGPFLVYCNMTD 319
+H+GN +G +YID+DGSGPLGP VYCN+T+
Sbjct: 595 RHQGNTAGFFYIDSDGSGPLGPLQVYCNITE 625
Score = 57.4 bits (137), Expect = 6e-08
Identities = 32/59 (54%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 884 GPVDEGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSKKE 942
G DE EPL NA R DSAVIGGVIAV IFI+ CI I R Q K + S++ +KE
Sbjct: 1221 GKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIMTRFLYQHK-QSHRTSQMKEKE 1278
Score = 41.6 bits (96), Expect = 0.004
Identities = 34/150 (22%), Positives = 55/150 (36%), Gaps = 30/150 (20%)
Query: 605 NDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQ------ 658
ND WH V +L +D + PAP V++ + + GG
Sbjct: 446 NDGLWHSVSINARRNRITLTLDD--EAAPPAPDSTWVQIYSGNSYYFGGCPDNLTDSQCL 503
Query: 659 ---RGFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYG------------HLCR 703
+ F GC+R + ++ DL V+ G G+ S + C
Sbjct: 504 NPIKAFQGCMRLIFIDNQPKDLIS-------VQQGSLGNFSDLHIDLCSIKDRCLPNYCE 556
Query: 704 NGGRCREKRRGVTCDCAFSAYDGPFCSNEI 733
+GG C + C+C+ ++Y G C N I
Sbjct: 557 HGGSCSQSWTTFYCNCSDTSYTGATCHNSI 586
Score = 36.2 bits (82), Expect = 0.15
Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 17/88 (19%)
Query: 195 GCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRC------LPSY 248
G S GF GC+R + + + +D L ++ + S G+ C S
Sbjct: 918 GTSSRQKGFLGCIRSLHLNGQKMD--LEERAKVTS---------GVRPGCPGHCSSYGSI 966
Query: 249 CEHGGECSQSWDTFSCDCLGTGYTGETC 276
C +GG+C + + + CDC + Y G C
Sbjct: 967 CHNGGKCVEKHNGYLCDCTNSPYEGPFC 994
Score = 35.0 bits (79), Expect = 0.33
Identities = 36/141 (25%), Positives = 58/141 (41%), Gaps = 17/141 (12%)
Query: 554 FKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTP-----FNDN 607
FK+ GV G D I +EL+ + ++G+ ++ P+ +D
Sbjct: 209 FKSMQGDGVLFHGEGQRGDHITLELQKG-RLALHLNLGDSKARLSSSLPSATLGSLLDDQ 267
Query: 608 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTAT-------RQRG 660
WH V ER K + VD+ Q + L ++ +L GG ++
Sbjct: 268 HWHSVLIERVGKQVNFTVDKHTQHFRTKGETD--ALDIDYELSFGGIPVPGKPGTFLKKN 325
Query: 661 FLGCIRSLQLNGV-ALDLEER 680
F GCI +L NGV +DL +R
Sbjct: 326 FHGCIENLYYNGVNIIDLAKR 346
>gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapiens]
Length = 1331
Score = 499 bits (1285), Expect = e-141
Identities = 243/469 (51%), Positives = 325/469 (69%), Gaps = 12/469 (2%)
Query: 428 GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVLS 487
G+P +WWVG+ NE H WGGS P QKC CG+E NC D +YYCNCDA +W D LS
Sbjct: 701 GSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYKQWRKDAGFLS 760
Query: 488 QKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELT 547
K+HLPV+Q+V+ D + SEA ++GPL C+GD+++WN+ASF +SYLHF F GE +
Sbjct: 761 YKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETS 820
Query: 548 ADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDN 607
AD+ F+FKT GVF+EN+G DFI++EL++ TEV+FSFDVGNGP E+ V+SPTP ND+
Sbjct: 821 ADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDD 880
Query: 608 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRS 667
QWH V AERNVK ASLQVD+LPQ+++ AP +GH RL+L SQLF+GG A Q+GFLGCIRS
Sbjct: 881 QWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGG-AGGQQGFLGCIRS 939
Query: 668 LQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGP 727
L++NGV LDLEERA V G GC+GHC++YG C NGG+C E+ G +CDC+ +AYDG
Sbjct: 940 LRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGT 999
Query: 728 FCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSL------HRDVTLTREMITLSFRT 781
FC+ ++ A+F G + Y+FQ T + +SSS V + H D L +E I SF T
Sbjct: 1000 FCNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPD--LAQEEIRFSFST 1057
Query: 782 TRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKI 841
T+ P +LLY+SSF ++L+V++ GSLQIRY L + P D +NMA+GQ H V I
Sbjct: 1058 TKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNI 1117
Query: 842 NREEAVVMVEVNQ--SAKKQVILSSGTEFNAVKSLILGKVLGRSGPVDE 888
R E + ++++ S + SS T FN+ KSL LGKV+ +G +D+
Sbjct: 1118 TRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVI-ETGKIDQ 1165
Score = 162 bits (410), Expect = 1e-39
Identities = 72/130 (55%), Positives = 92/130 (70%), Gaps = 2/130 (1%)
Query: 190 NSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYC 249
N+S P FQGC++LI + D+ V+ V Q GSF ++ ID C I DRC+P++C
Sbjct: 506 NNSSHSVLQP--SFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHC 563
Query: 250 EHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLG 309
EHGG+CSQ+WD+F C C TGY+G TCH+S+YE SCEA+KH G S Y+ID DGSGPLG
Sbjct: 564 EHGGKCSQTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLG 623
Query: 310 PFLVYCNMTD 319
P VYCNMT+
Sbjct: 624 PLKVYCNMTE 633
Score = 62.8 bits (151), Expect = 1e-09
Identities = 57/242 (23%), Positives = 94/242 (38%), Gaps = 29/242 (11%)
Query: 530 FNTETSYLHFPAFHGELTADVCFFFKTTVSSGV-----FMENLGITDFIRIELRAPTEVT 584
F TSYL P + V F F+T +G+ F +NLG + E + +
Sbjct: 377 FFNATSYLEVPGRLNQDLFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHIN 436
Query: 585 FSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQ 644
+ ++ + S + ND QWH VR A L +D + + ++++
Sbjct: 437 IT---QTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTIDG--DEASAVRTNSPLQVK 491
Query: 645 LNSQLFIGGTATR---------QRGFLGCIRSLQLNGVALDLEERATVMPGVEPG----- 690
+ F GG + Q F GC++ +Q++ ++L E A PG
Sbjct: 492 TGEKYFFGGFLNQMNNSSHSVLQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDM 551
Query: 691 CAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEI-----SAYFATGSSMTY 745
CA + C +GG+C + C C + Y G C N I AY G + Y
Sbjct: 552 CAIIDRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNY 611
Query: 746 HF 747
++
Sbjct: 612 YW 613
Score = 48.9 bits (115), Expect = 2e-05
Identities = 42/147 (28%), Positives = 74/147 (50%), Gaps = 19/147 (12%)
Query: 554 FKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGN---GPC--EVTVQSPTPFNDN 607
FKT+ S GV + G D+I +EL+ ++ S ++G+ GP +V + + +D+
Sbjct: 216 FKTSESEGVILHGEGQQGDYITLELKK-AKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDH 274
Query: 608 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHV-RLQLNSQLFIGG-------TATRQR 659
WH V ER + +L +D + MQ +G L L+ ++ GG +++ ++
Sbjct: 275 HWHSVVIERQGRSINLTLD---RSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRK 331
Query: 660 GFLGCIRSLQLNGVAL-DLEERATVMP 685
F GC+ S+ NGV + DL R + P
Sbjct: 332 NFKGCMESINYNGVNITDLARRKKLEP 358
Score = 42.0 bits (97), Expect = 0.003
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 202 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 261
GF GC+R + + +D L ++ + S I C + CE+GG+C + +
Sbjct: 932 GFLGCIRSLRMNGVTLD--LEERAKVTSGF---ISGCSGHCTSYGTNCENGGKCLERYHG 986
Query: 262 FSCDCLGTGYTGETCHSSL 280
+SCDC T Y G C+ +
Sbjct: 987 YSCDCSNTAYDGTFCNKDV 1005
Score = 41.6 bits (96), Expect = 0.004
Identities = 22/57 (38%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
Query: 888 EGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIR-IYQQRKLRKENESKVSKKEE 943
+G+ + N R+SA+IGGVIAV IF +LC IR +++ + NE+K ++ E
Sbjct: 1249 QGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKGAESAE 1305
Score = 32.7 bits (73), Expect = 1.6
Identities = 30/140 (21%), Positives = 53/140 (37%), Gaps = 15/140 (10%)
Query: 549 DVCFFFKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGNG--PCEVTVQSPTPFN 605
++ F F TT + + + T DF+ + ++ + +++G P + V N
Sbjct: 1050 EIRFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMAN 1109
Query: 606 DNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQR------ 659
Q H V R+ K L++D P P+ LF+G +
Sbjct: 1110 -GQPHSVNITRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIH 1168
Query: 660 -----GFLGCIRSLQLNGVA 674
GF GC+ +Q N +A
Sbjct: 1169 KYNTPGFTGCLSRVQFNQIA 1188
>gi|4505463 contactin associated protein 1 precursor [Homo sapiens]
Length = 1384
Score = 344 bits (882), Expect = 3e-94
Identities = 184/512 (35%), Positives = 286/512 (55%), Gaps = 56/512 (10%)
Query: 428 GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVLS 487
G P S+W+GR E H WGGS P Q+C CGL+ +C+D YCNCDA + +W +D +L+
Sbjct: 688 GYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQWRTDKGLLT 747
Query: 488 QKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELT 547
+HLPVTQ+V+ D + SEA + L PL C GD++ WN+ SF+T + L FP +
Sbjct: 748 FVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRFPPIRANHS 806
Query: 548 ADVCFFFKTTVSSGVFMENLG------ITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSP 601
DV F+F+T+ SGVF+EN+G ++R+EL +V F+FDVGNG +TV S
Sbjct: 807 LDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDENLTVHSD 866
Query: 602 T-PFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRG 660
FND++WH VRAE NVK A L+VD P ++P P ++ ++ + L++G ++R
Sbjct: 867 DFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVGSAELKRRP 926
Query: 661 FLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCA 720
F+GC+R+++LNGV L+LE RA G P C GHC+ C +GGRC E+ TCDC
Sbjct: 927 FVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERYSYYTCDCD 986
Query: 721 FSAYDGPFCSNEISAYFATGSSMTYHFQE----------------------HYTLSENSS 758
+A+DGP+C+++I +F G+ M Y+ Q Y ++
Sbjct: 987 LTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGYIPGYDTP 1046
Query: 759 SLVSSLH-------------RDV--------TLTREMITLSFRTTRTPSLLLYVSSFYEE 797
V H R V +T E ++ SF T+ P++LLYVSSF +
Sbjct: 1047 GYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYVSSFVRD 1106
Query: 798 YLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINR--EEAVVMVEVNQS 855
Y++V++ ++G+LQ+RY+L +P + + + DGQ H + I R + V+
Sbjct: 1107 YMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITRVYRNLFIQVDYFPL 1164
Query: 856 AKKQVILSSGTEFNAVKSLILGKVLGRSGPVD 887
+++ L ++ ++ K+L LG+V+ +G +D
Sbjct: 1165 TEQKFSLLVDSQLDSPKALYLGRVM-ETGVID 1195
Score = 142 bits (359), Expect = 1e-33
Identities = 65/136 (47%), Positives = 87/136 (63%)
Query: 187 CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 246
C +S C S F GC+ L+ + + V+ LV+ LG + ++ D+CGITDRC P
Sbjct: 487 CPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSP 546
Query: 247 SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 306
+ CEH G C QSWD F C C TGY GETCH+ LY++SCEA++ G SG + ID DGSG
Sbjct: 547 NMCEHDGRCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSG 606
Query: 307 PLGPFLVYCNMTDRSA 322
PL PF+VYC++ + A
Sbjct: 607 PLKPFVVYCDIRENRA 622
Score = 46.2 bits (108), Expect = 1e-04
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 16/135 (11%)
Query: 552 FFFKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGNGPCE-----VTVQSPTPFN 605
F FKT G+ + G D++ +EL + +G+ P + TV + N
Sbjct: 201 FSFKTEEKDGLLLHAEGAQGDYVTLELEG-AHLLLHMSLGSSPIQPRPGHTTVSAGGVLN 259
Query: 606 DNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQR------ 659
D WH+VR +R + + +D Q+ RL L++++FIGG R
Sbjct: 260 DQHWHYVRVDRFGRDVNFTLDGYVQRF--ILNGDFERLNLDTEMFIGGLVGAARKNLAYR 317
Query: 660 -GFLGCIRSLQLNGV 673
F GCI ++ N V
Sbjct: 318 HNFRGCIENVIFNRV 332
Score = 35.4 bits (80), Expect = 0.25
Identities = 46/222 (20%), Positives = 80/222 (36%), Gaps = 30/222 (13%)
Query: 529 SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFM-----ENLGITDFIRIELRAPTEV 583
+F +++ P F V F F+T +G+ + + LG + E + +
Sbjct: 364 NFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSI 423
Query: 584 TFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRL 643
S G ++ + ND WH V A + +D + + + +
Sbjct: 424 AQS-----GRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDV--EGAEVRVSYPLLI 476
Query: 644 QLNSQLFIGGTA---------TRQRGFLGCIRSLQLNG--VALDLEERATVMPGVEP--- 689
+ + F GG + Q F GC+ L+++G V L L E + E
Sbjct: 477 RTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFD 536
Query: 690 --GCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFC 729
G CS ++C + GRC + C C + Y G C
Sbjct: 537 TCGITDRCSP--NMCEHDGRCYQSWDDFICYCELTGYKGETC 576
Score = 33.5 bits (75), Expect = 0.96
Identities = 11/32 (34%), Positives = 18/32 (56%)
Query: 249 CEHGGECSQSWDTFSCDCLGTGYTGETCHSSL 280
C HGG C + + ++CDC T + G C+ +
Sbjct: 968 CFHGGRCVERYSYYTCDCDLTAFDGPYCNHDI 999
Score = 32.7 bits (73), Expect = 1.6
Identities = 31/138 (22%), Positives = 55/138 (39%), Gaps = 13/138 (9%)
Query: 549 DVCFFFKTTVSSGVFME-NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDN 607
+V F F T+ + V + + + D++ + ++ + + +G P V + P D
Sbjct: 1083 EVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGTSPY-VYQLTTRPVTDG 1141
Query: 608 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATR-------QR- 659
Q H + R + +QVD P Q +L L++G QR
Sbjct: 1142 QPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRY 1201
Query: 660 ---GFLGCIRSLQLNGVA 674
GF GC+ ++ N VA
Sbjct: 1202 NTPGFSGCLSGVRFNNVA 1219
>gi|169184330 PREDICTED: novel protein similar to contactin
associated protein-like 3 (CNTNAP3) [Homo sapiens]
Length = 291
Score = 290 bits (741), Expect = 6e-78
Identities = 149/153 (97%), Positives = 151/153 (98%)
Query: 732 EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYV 791
+ISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYV
Sbjct: 2 KISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYV 61
Query: 792 SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 851
SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE
Sbjct: 62 SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 121
Query: 852 VNQSAKKQVILSSGTEFNAVKSLILGKVLGRSG 884
VNQSAKKQVILSSGTEFNAVKSLILGKVL +G
Sbjct: 122 VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAG 154
Score = 127 bits (318), Expect = 6e-29
Identities = 64/64 (100%), Positives = 64/64 (100%)
Query: 881 GRSGPVDEGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSK 940
GRSGPVDEGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSK
Sbjct: 228 GRSGPVDEGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSK 287
Query: 941 KEEC 944
KEEC
Sbjct: 288 KEEC 291
>gi|239758135 PREDICTED: similar to cell recognition molecule CASPR3
[Homo sapiens]
Length = 140
Score = 272 bits (696), Expect = 9e-73
Identities = 139/140 (99%), Positives = 140/140 (100%)
Query: 743 MTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVI 802
MTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVI
Sbjct: 1 MTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVI 60
Query: 803 LANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVIL 862
LANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVIL
Sbjct: 61 LANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVIL 120
Query: 863 SSGTEFNAVKSLILGKVLGR 882
SSGTEFNAVKSLILGKVLG+
Sbjct: 121 SSGTEFNAVKSLILGKVLGK 140
>gi|239752499 PREDICTED: similar to cell recognition molecule
Caspr2, partial [Homo sapiens]
Length = 140
Score = 146 bits (368), Expect = 1e-34
Identities = 74/74 (100%), Positives = 74/74 (100%)
Query: 807 GSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGT 866
GSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGT
Sbjct: 2 GSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGT 61
Query: 867 EFNAVKSLILGKVL 880
EFNAVKSLILGKVL
Sbjct: 62 EFNAVKSLILGKVL 75
>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
Length = 1477
Score = 114 bits (286), Expect = 3e-25
Identities = 99/371 (26%), Positives = 168/371 (45%), Gaps = 45/371 (12%)
Query: 529 SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI-TDFIRIELRAPTEVTFSF 587
+F T++SY+ + + F FKTT G+ + N G DFI +EL + + F
Sbjct: 908 TFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVEL-VKGYLHYVF 966
Query: 588 DVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNS 647
D+GNG + S P NDNQWH+V R+ ++L ++ K+ G L L S
Sbjct: 967 DLGNGANLIKGSSNKPLNDNQWHNVMISRDT--SNLHTVKIDTKITTQITAGARNLDLKS 1024
Query: 648 QLFIGGTATR-----------QRGFLGCIRSLQLNGVALDLEERATVMPG-VEPGCAGHC 695
L+IGG A + GF GC+ S+ LNG DL A G +E GC G
Sbjct: 1025 DLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPS 1084
Query: 696 ST-YGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFAT--GSSMTYHFQEHYT 752
+T C N G C ++ G +CDC+ +++ GP C++ + Y + G +TY + +
Sbjct: 1085 TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDR 1144
Query: 753 LSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYV--SSFYEEYLSVILANNGSLQ 810
S + + + + F T + ++L+ V SS +YL + + + G +
Sbjct: 1145 PSTRA---------------DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHI-HQGKIG 1188
Query: 811 IRYKLDRHQNPDAFTFDFKN--MADGQLHQVKINRE--EAVVMVEVNQSAKKQVILSSGT 866
+++ + D + N + DG+ H V+ R A + V+ ++ T
Sbjct: 1189 VKFNV----GTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLT 1244
Query: 867 EFNAVKSLILG 877
FN+ ++I+G
Sbjct: 1245 IFNSQATIIIG 1255
Score = 90.1 bits (222), Expect = 9e-18
Identities = 82/355 (23%), Positives = 150/355 (42%), Gaps = 61/355 (17%)
Query: 529 SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI--------------TDFIR 574
+F T S++ P ++ + T + F F+TT +G+ + + G DF
Sbjct: 483 TFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFA 542
Query: 575 IELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQP 634
IE+ + D+G+G ++ ND +W+HV +R+ + ++ V+ L +
Sbjct: 543 IEM-LDGHLYLLLDMGSGTIKIKALLKK-VNDGEWYHVDFQRDGRSGTISVNTL-RTPYT 599
Query: 635 APADGHVRLQLNSQLFIGG---------------TATRQRGFLGCIRSLQLNGVALDLEE 679
AP + + L L+ +L++GG TA G++GCIR L ++G + D+ +
Sbjct: 600 APGESEI-LDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQ 658
Query: 680 RATVMP--GVEPGCAGHCST--YGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISA 735
A V GV+P C+ + + C+N G CR+ CDC+ + Y G C E +
Sbjct: 659 MAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATV 718
Query: 736 YFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFY 795
GS L +H + E ++L FR+ R +L+ +S
Sbjct: 719 LSYDGSMFM------------KIQLPVVMHTEA----EDVSLRFRSQRAYGILMATTSRD 762
Query: 796 EEYLSVILANNGSLQIRYKLD-------RHQNPDAFTFDFKNMADGQLHQVKINR 843
+ + G +++ LD + P+ F N+ D + H V++ R
Sbjct: 763 SADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETL-FAGYNLNDNEWHTVRVVR 816
Score = 73.6 bits (179), Expect = 8e-13
Identities = 73/304 (24%), Positives = 125/304 (41%), Gaps = 34/304 (11%)
Query: 533 ETSYLHFPAFHGELTADVCFFFKTTVSSGV--FMENLGITDFIRIELRAPTEVTFSFDVG 590
E + FP ++ +++ F KT + G+ + ++ G DF+ + L + SF +
Sbjct: 37 EGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIF 96
Query: 591 NGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLF 650
T+ + TP ND WH VR R + +L +DQ+ K + + + S LF
Sbjct: 97 CAE-PATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRR-DMTVFSGLF 154
Query: 651 IGG--------------TATRQR-GFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHC 695
+GG + R+R F G IR +++N + + V EP +G
Sbjct: 155 VGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGG 214
Query: 696 ST-------YGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEIS-----AYFATGSSM 743
S G +C NGG C CDC+ + + G CS E + A+ G
Sbjct: 215 SPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQG 274
Query: 744 TYHFQEHY--TLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSV 801
+E Y T + + + + ITLSF+T + L+L+ +Y+++
Sbjct: 275 KSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK-SADYVNL 333
Query: 802 ILAN 805
L N
Sbjct: 334 ALKN 337
Score = 50.1 bits (118), Expect = 1e-05
Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Query: 202 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 261
GFQGCL + + + D I AL ++ G + C C + G C Q WD
Sbjct: 1048 GFQGCLASVDLNGRLPDLI---SDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDG 1104
Query: 262 FSCDCLGTGYTGETCH 277
FSCDC T ++G C+
Sbjct: 1105 FSCDCSMTSFSGPLCN 1120
Score = 48.1 bits (113), Expect = 4e-05
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
Query: 202 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDR-CLPSYCEHGGECSQSWD 260
G+ GC+R + I ++ D + Q + S ++ T + CL + C++ G C W+
Sbjct: 639 GYVGCIRDLFIDGQSKD--IRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWN 696
Query: 261 TFSCDCLGTGYTGETC 276
+ CDC GTGY G +C
Sbjct: 697 RYVCDCSGTGYLGRSC 712
Score = 47.4 bits (111), Expect = 6e-05
Identities = 78/317 (24%), Positives = 115/317 (36%), Gaps = 82/317 (25%)
Query: 549 DVCFFFKTTVSSGVFMENLG--ITDFIRIELRAP-TEVTFSFDVGNGPCEVTVQSPTPF- 604
DV F++ + G+ M D +R+EL A ++T + D C + T F
Sbjct: 741 DVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFA 800
Query: 605 ----NDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQR- 659
NDN+WH VR R K L VD Q M A H RL+ ++ G T +R
Sbjct: 801 GYNLNDNEWHTVRVVRRGKSLKLTVDD-QQAMTGQMAGDHTRLEFHN--IETGIITERRY 857
Query: 660 ------GFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGG------R 707
F+G ++SL NG+A Y LC+NG
Sbjct: 858 LSSVPSNFIGHLQSLTFNGMA-----------------------YIDLCKNGDIDYCELN 894
Query: 708 CREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRD 767
R R + D P S+Y A + Y +S+H
Sbjct: 895 ARFGFRNIIAD--------PVTFKTKSSYVALATLQAY----------------TSMH-- 928
Query: 768 VTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFD 827
+ F+TT L+LY S +++ V L G L + L N + +
Sbjct: 929 -------LFFQFKTTSLDGLILYNSGDGNDFIVVELV-KGYLHYVFDLGNGANLIKGSSN 980
Query: 828 FKNMADGQLHQVKINRE 844
K + D Q H V I+R+
Sbjct: 981 -KPLNDNQWHNVMISRD 996
Score = 43.9 bits (102), Expect = 7e-04
Identities = 58/268 (21%), Positives = 104/268 (38%), Gaps = 42/268 (15%)
Query: 439 NETHTSWGGSLPDAQK------CTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVLSQKEHL 492
+E S GGS +A + C G + +D Q C+C R +
Sbjct: 206 DEPPNSGGGSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCS--RTGFRGKDCSQEDNNVE 263
Query: 493 PVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCF 552
+ ++M D G+ + +Y +F S F + S + E+T
Sbjct: 264 GLAHLMMGDQGKSKGKEEYIA---------TFKGSEYFCYDLSQNPIQSSSDEITLS--- 311
Query: 553 FFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPT-PFNDNQWHH 611
FKT +G+ + D++ + L+ V+ ++G+G E V+ FNDN WH
Sbjct: 312 -FKTLQRNGLMLHTGKSADYVNLALKNGA-VSLVINLGSGAFEALVEPVNGKFNDNAWHD 369
Query: 612 VRAERNVKGAS--------LQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATR------ 657
V+ RN++ S + VD + D + L + ++GG+ +
Sbjct: 370 VKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQED-YTMLGSDDFFYVGGSPSTADLPGS 428
Query: 658 --QRGFLGCIRSL--QLNGVALDLEERA 681
F+GC++ + + N V L+L A
Sbjct: 429 PVSNNFMGCLKEVVYKNNDVRLELSRLA 456
Score = 32.0 bits (71), Expect = 2.8
Identities = 13/28 (46%), Positives = 16/28 (57%)
Query: 249 CEHGGECSQSWDTFSCDCLGTGYTGETC 276
C +GG CS D CDC TG+ G+ C
Sbjct: 228 CLNGGVCSVVDDQAVCDCSRTGFRGKDC 255
>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
Length = 1547
Score = 114 bits (285), Expect = 4e-25
Identities = 105/402 (26%), Positives = 180/402 (44%), Gaps = 48/402 (11%)
Query: 529 SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI-TDFIRIELRAPTEVTFSF 587
+F T++SY+ + + F FKTT G+ + N G DFI +EL + + F
Sbjct: 948 TFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVEL-VKGYLHYVF 1006
Query: 588 DVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNS 647
D+GNG + S P NDNQWH+V R+ ++L ++ K+ G L L S
Sbjct: 1007 DLGNGANLIKGSSNKPLNDNQWHNVMISRDT--SNLHTVKIDTKITTQITAGARNLDLKS 1064
Query: 648 QLFIGGTATR-----------QRGFLGCIRSLQLNGVALDLEERATVMPG-VEPGCAGHC 695
L+IGG A + GF GC+ S+ LNG DL A G +E GC G
Sbjct: 1065 DLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPS 1124
Query: 696 ST-YGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFAT--GSSMTYHFQEHYT 752
+T C N G C ++ G +CDC+ +++ GP C++ + Y + G +TY + +
Sbjct: 1125 TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDR 1184
Query: 753 LSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYV--SSFYEEYLSVILANNGSLQ 810
S + + + + F T + ++L+ V SS +YL + + + G +
Sbjct: 1185 PSTRA---------------DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHI-HQGKIG 1228
Query: 811 IRYKLDRHQNPDAFTFDFKN--MADGQLHQVKINRE--EAVVMVEVNQSAKKQVILSSGT 866
+++ + D + N + DG+ H V+ R A + V+ ++ ++
Sbjct: 1229 VKFNV----GTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDN 1284
Query: 867 EFNAVKSLILGKVLGR---SGPVDEGEPLVNADRRDSAVIGG 905
E A+ + LGR +D+G L + + + +IGG
Sbjct: 1285 ERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGG 1326
Score = 90.1 bits (222), Expect = 9e-18
Identities = 82/355 (23%), Positives = 150/355 (42%), Gaps = 61/355 (17%)
Query: 529 SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI--------------TDFIR 574
+F T S++ P ++ + T + F F+TT +G+ + + G DF
Sbjct: 523 TFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFA 582
Query: 575 IELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQP 634
IE+ + D+G+G ++ ND +W+HV +R+ + ++ V+ L +
Sbjct: 583 IEM-LDGHLYLLLDMGSGTIKIKALLKK-VNDGEWYHVDFQRDGRSGTISVNTL-RTPYT 639
Query: 635 APADGHVRLQLNSQLFIGG---------------TATRQRGFLGCIRSLQLNGVALDLEE 679
AP + + L L+ +L++GG TA G++GCIR L ++G + D+ +
Sbjct: 640 APGESEI-LDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQ 698
Query: 680 RATVMP--GVEPGCAGHCST--YGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISA 735
A V GV+P C+ + + C+N G CR+ CDC+ + Y G C E +
Sbjct: 699 MAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCEREATV 758
Query: 736 YFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFY 795
GS L +H + E ++L FR+ R +L+ +S
Sbjct: 759 LSYDGSMFM------------KIQLPVVMHTEA----EDVSLRFRSQRAYGILMATTSRD 802
Query: 796 EEYLSVILANNGSLQIRYKLD-------RHQNPDAFTFDFKNMADGQLHQVKINR 843
+ + G +++ LD + P+ F N+ D + H V++ R
Sbjct: 803 SADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETL-FAGYNLNDNEWHTVRVVR 856
Score = 67.8 bits (164), Expect = 5e-11
Identities = 58/225 (25%), Positives = 95/225 (42%), Gaps = 26/225 (11%)
Query: 533 ETSYLHFPAFHGELTADVCFFFKTTVSSGV--FMENLGITDFIRIELRAPTEVTFSFDVG 590
E + FP ++ +++ F KT + G+ + ++ G DF+ + L + SF +
Sbjct: 37 EGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIF 96
Query: 591 NGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLF 650
T+ + TP ND WH VR R + +L +DQ+ K + + + S LF
Sbjct: 97 CAE-PATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRR-DMTVFSGLF 154
Query: 651 IGG--------------TATRQR-GFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHC 695
+GG + R+R F G IR +++N + + V EP +G
Sbjct: 155 VGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGG 214
Query: 696 ST-------YGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEI 733
S G +C NGG C CDC+ + + G CS EI
Sbjct: 215 SPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEI 259
Score = 50.1 bits (118), Expect = 1e-05
Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Query: 202 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 261
GFQGCL + + + D I AL ++ G + C C + G C Q WD
Sbjct: 1088 GFQGCLASVDLNGRLPDLI---SDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDG 1144
Query: 262 FSCDCLGTGYTGETCH 277
FSCDC T ++G C+
Sbjct: 1145 FSCDCSMTSFSGPLCN 1160
Score = 48.1 bits (113), Expect = 4e-05
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
Query: 202 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDR-CLPSYCEHGGECSQSWD 260
G+ GC+R + I ++ D + Q + S ++ T + CL + C++ G C W+
Sbjct: 679 GYVGCIRDLFIDGQSKD--IRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWN 736
Query: 261 TFSCDCLGTGYTGETC 276
+ CDC GTGY G +C
Sbjct: 737 RYVCDCSGTGYLGRSC 752
Score = 47.4 bits (111), Expect = 6e-05
Identities = 78/317 (24%), Positives = 115/317 (36%), Gaps = 82/317 (25%)
Query: 549 DVCFFFKTTVSSGVFMENLG--ITDFIRIELRAP-TEVTFSFDVGNGPCEVTVQSPTPF- 604
DV F++ + G+ M D +R+EL A ++T + D C + T F
Sbjct: 781 DVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFA 840
Query: 605 ----NDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQR- 659
NDN+WH VR R K L VD Q M A H RL+ ++ G T +R
Sbjct: 841 GYNLNDNEWHTVRVVRRGKSLKLTVDD-QQAMTGQMAGDHTRLEFHN--IETGIITERRY 897
Query: 660 ------GFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGG------R 707
F+G ++SL NG+A Y LC+NG
Sbjct: 898 LSSVPSNFIGHLQSLTFNGMA-----------------------YIDLCKNGDIDYCELN 934
Query: 708 CREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRD 767
R R + D P S+Y A + Y +S+H
Sbjct: 935 ARFGFRNIIAD--------PVTFKTKSSYVALATLQAY----------------TSMH-- 968
Query: 768 VTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFD 827
+ F+TT L+LY S +++ V L G L + L N + +
Sbjct: 969 -------LFFQFKTTSLDGLILYNSGDGNDFIVVELV-KGYLHYVFDLGNGANLIKGSSN 1020
Query: 828 FKNMADGQLHQVKINRE 844
K + D Q H V I+R+
Sbjct: 1021 -KPLNDNQWHNVMISRD 1036
Score = 38.9 bits (89), Expect = 0.023
Identities = 51/210 (24%), Positives = 84/210 (40%), Gaps = 34/210 (16%)
Query: 439 NETHTSWGGSLPDAQK------CTCGLEGNCIDSQYYCNCDAG--RNEWTSDTIVLSQKE 490
+E S GGS +A + C G + +D Q C+C R + S I +
Sbjct: 206 DEPPNSGGGSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEIKFGLQC 265
Query: 491 HLPVT-------QIVMTDAGQPHSEADYTLGPL--LCRGDK-----------SFWNSASF 530
LPV + + +P +E D + L L GD+ +F S F
Sbjct: 266 VLPVLLHDNDQGKYCCINTAKPLTEKDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYF 325
Query: 531 NTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVG 590
+ S + E+T FKT +G+ + D++ + L+ V+ ++G
Sbjct: 326 CYDLSQNPIQSSSDEITLS----FKTLQRNGLMLHTGKSADYVNLALKNGA-VSLVINLG 380
Query: 591 NGPCEVTVQSPT-PFNDNQWHHVRAERNVK 619
+G E V+ FNDN WH V+ RN++
Sbjct: 381 SGAFEALVEPVNGKFNDNAWHDVKVTRNLR 410
Score = 32.3 bits (72), Expect = 2.1
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 249 CEHGGECSQSWDTFSCDCLGTGYTGETCHSSL 280
C +GG CS D CDC TG+ G+ C +
Sbjct: 228 CLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEI 259
>gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]
Length = 1642
Score = 112 bits (280), Expect = 2e-24
Identities = 108/383 (28%), Positives = 172/383 (44%), Gaps = 48/383 (12%)
Query: 529 SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI-TDFIRIELRAPTEVTFSF 587
+F + +SYL + + F FKTT G+ + N G DFI IEL + + F
Sbjct: 881 TFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIEL-VKGYIHYVF 939
Query: 588 DVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNS 647
D+GNGP + S P NDNQWH+V R+ ++ ++ + ++G L L
Sbjct: 940 DLGNGPSLMKGNSDKPVNDNQWHNVVVSRD--PGNVHTLKIDSRTVTQHSNGARNLDLKG 997
Query: 648 QLFIGGTA-----------TRQRGFLGCIRSLQLNGVALDLEERATVMPG-VEPGCAGHC 695
+L+IGG + + GF GC+ S+ LNG DL A G VE GC G
Sbjct: 998 ELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGPS 1057
Query: 696 ST-YGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAY-FATGSSMTYHFQEHYTL 753
+T C N G C ++ G TCDC ++Y GP C++ + Y F G ++ YT
Sbjct: 1058 TTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPGTTYIFGKGGALI-----TYTW 1112
Query: 754 SENSSSLVSSLHRDVTLTR-EMITLSFRTTRTPSLLLYV--SSFYEEYLSVILANNGSLQ 810
N D TR + + + F T + ++L+ V +S +YL + + + G++
Sbjct: 1113 PPN----------DRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI-DQGTVG 1161
Query: 811 IRYKLDRHQNPDAFTFDFKN--MADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEF 868
+ + + D T D N ++DG+ H V+ R ++V+ S +G +
Sbjct: 1162 VIFNV----GTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD-SWPVNERYPAGRQL 1216
Query: 869 NAVKSLILGKVLGRSGPVDEGEP 891
S K+ GR D+G P
Sbjct: 1217 TIFNSQAAIKIGGR----DQGRP 1235
Score = 76.3 bits (186), Expect = 1e-13
Identities = 82/370 (22%), Positives = 151/370 (40%), Gaps = 63/370 (17%)
Query: 521 DKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI----------- 569
D + + +F + +++ P + + T + F+TT +G+ + + G
Sbjct: 457 DVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGGGAGSHSS 516
Query: 570 ---TDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVD 626
D+ +EL + D+G+G ++ S ND +W HV +R+ + S+ V+
Sbjct: 517 AQRADYFAMEL-LDGHLYLLLDMGSGGIKLRASS-RKVNDGEWCHVDFQRDGRKGSISVN 574
Query: 627 QLPQKMQPAPADGHVR-LQLNSQLFIGG----------------TATRQRGFLGCIRSLQ 669
+ P A G L L S+L++GG TA + G++GC+R L
Sbjct: 575 S---RSTPFLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVRDLF 631
Query: 670 LNGVALDLEERATVMP--GVEPGCAGH----CSTYGHLCRNGGRCREKRRGVTCDCAFSA 723
++G + DL A GV P C+ C++ CRNGG CRE CDC +
Sbjct: 632 IDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAP--CRNGGVCREGWNRFICDCIGTG 689
Query: 724 YDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTR 783
+ G C E + GS L +++H + E ++L F + R
Sbjct: 690 FLGRVCEREATVLSYDGSMYM------------KIMLPNAMHTEA----EDVSLRFMSQR 733
Query: 784 TPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINR 843
L++ +S E + Q++ ++ + P+ F + D + H V++ R
Sbjct: 734 AYGLMMATTS--RESADTLRLELDGGQMKLTVNLGKGPETL-FAGHKLNDNEWHTVRVVR 790
Query: 844 EEAVVMVEVN 853
+ + V+
Sbjct: 791 RGKSLQLSVD 800
Score = 58.5 bits (140), Expect = 3e-08
Identities = 58/218 (26%), Positives = 87/218 (39%), Gaps = 36/218 (16%)
Query: 597 TVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGG--- 653
T+Q TP D++WH V R+ + +L VD + +Q+ S LF+GG
Sbjct: 100 TLQLDTPVADDRWHMVLLTRDARRTALAVD--GEARAAEVRSKRREMQVASDLFVGGIPP 157
Query: 654 ----------TATRQRGFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGH-----CSTY 698
T + F G + +L+L ER + G + G G C+
Sbjct: 158 DVRLSALTLSTVKYEPPFRGLLANLKLG-------ERPPALLGSQ-GLRGATADPLCAPA 209
Query: 699 GHLCRNGGRCREKRRG-VTCDCAFSAYDGPFCSNEI-----SAYFATGSSMTYHFQEHYT 752
+ C NGG C G V CDC+ + + G FCS E A+ S F T
Sbjct: 210 RNPCANGGLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEGKEEFVA--T 267
Query: 753 LSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLY 790
N H + + + ITL+FRT + L+L+
Sbjct: 268 FKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLH 305
Score = 52.0 bits (123), Expect = 3e-06
Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 5/77 (6%)
Query: 202 GFQGCLRLITIGDKAVD--PILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSW 259
G+ GC+R + I ++ D + QGA+G S +C + C +GG C + W
Sbjct: 622 GYVGCVRDLFIDGRSRDLRGLAEAQGAVGV---APFCSRETLKQCASAPCRNGGVCREGW 678
Query: 260 DTFSCDCLGTGYTGETC 276
+ F CDC+GTG+ G C
Sbjct: 679 NRFICDCIGTGFLGRVC 695
Score = 51.2 bits (121), Expect = 4e-06
Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 3/76 (3%)
Query: 202 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 261
GFQGCL + + + D I AL ++ G + C C + G C Q WD
Sbjct: 1021 GFQGCLASVDLNGRLPDLIA---DALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDG 1077
Query: 262 FSCDCLGTGYTGETCH 277
F+CDC T Y G C+
Sbjct: 1078 FTCDCTMTSYGGPVCN 1093
Score = 43.9 bits (102), Expect = 7e-04
Identities = 73/314 (23%), Positives = 114/314 (36%), Gaps = 71/314 (22%)
Query: 541 AFHGELTADVCFFFKTTVSSGVFMENLG--ITDFIRIELRAPTEVTFSFDVGNGPCEVTV 598
A H E DV F + + G+ M D +R+EL ++ + ++G GP T+
Sbjct: 717 AMHTE-AEDVSLRFMSQRAYGLMMATTSRESADTLRLELDGG-QMKLTVNLGKGP--ETL 772
Query: 599 QSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQ 658
+ NDN+WH VR R K L VD + + Q A A H+RL+ ++ G T +
Sbjct: 773 FAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEGQMAGA--HMRLEFHN--IETGIMTER 828
Query: 659 R-------GFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREK 711
R F+G + L NG M + G +C R
Sbjct: 829 RFISVVPSNFIGHLSGLVFNG--------QPYMDQCKDGDITYCEL---------NARFG 871
Query: 712 RRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLT 771
R + D P S+Y A + Y +S+H
Sbjct: 872 LRAIVAD--------PVTFKSRSSYLALATLQAY----------------ASMH------ 901
Query: 772 REMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDF-KN 830
+ F+TT LLL+ S +++ + L I Y D P + K
Sbjct: 902 ---LFFQFKTTAPDGLLLFNSGNGNDFIVIELVKG---YIHYVFDLGNGPSLMKGNSDKP 955
Query: 831 MADGQLHQVKINRE 844
+ D Q H V ++R+
Sbjct: 956 VNDNQWHNVVVSRD 969
Score = 40.0 bits (92), Expect = 0.010
Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 2/74 (2%)
Query: 547 TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPT-PFN 605
T ++ F+T +G+ + D++ + L++ V ++G+G E V+ FN
Sbjct: 287 TDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGA-VWLVINLGSGAFEALVEPVNGKFN 345
Query: 606 DNQWHHVRAERNVK 619
DN WH VR RN++
Sbjct: 346 DNAWHDVRVTRNLR 359
Score = 34.7 bits (78), Expect = 0.43
Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 775 ITLSFRTTRTPSLLLYVSSFYE-EYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMAD 833
++ S RT T +LLLY+ + ++L ++L + G L++R+ L + P D +AD
Sbjct: 53 LSFSLRTNATRALLLYLDDGGDCDFLELLLVD-GRLRLRFTLSCAE-PATLQLDTP-VAD 109
Query: 834 GQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKV 879
+ H V + R+ + V+ A+ + S E L +G +
Sbjct: 110 DRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGI 155
Score = 30.8 bits (68), Expect = 6.2
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 13/89 (14%)
Query: 203 FQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSY--CEHGGECSQ-SW 259
F+G L + +G++ +L QG G+ D C P+ C +GG C+ +
Sbjct: 175 FRGLLANLKLGERP-PALLGSQGLRGATAD---------PLCAPARNPCANGGLCTVLAP 224
Query: 260 DTFSCDCLGTGYTGETCHSSLYEQSCEAH 288
CDC TG+ G+ C + AH
Sbjct: 225 GEVGCDCSHTGFGGKFCSEEEHPMEGPAH 253
>gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]
Length = 1712
Score = 111 bits (278), Expect = 3e-24
Identities = 99/345 (28%), Positives = 159/345 (46%), Gaps = 43/345 (12%)
Query: 529 SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI-TDFIRIELRAPTEVTFSF 587
+F + +SYL + + F FKTT G+ + N G DFI IEL + + F
Sbjct: 921 TFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIEL-VKGYIHYVF 979
Query: 588 DVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNS 647
D+GNGP + S P NDNQWH+V R+ ++ ++ + ++G L L
Sbjct: 980 DLGNGPSLMKGNSDKPVNDNQWHNVVVSRD--PGNVHTLKIDSRTVTQHSNGARNLDLKG 1037
Query: 648 QLFIGGTA-----------TRQRGFLGCIRSLQLNGVALDLEERATVMPG-VEPGCAGHC 695
+L+IGG + + GF GC+ S+ LNG DL A G VE GC G
Sbjct: 1038 ELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGPS 1097
Query: 696 ST-YGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAY-FATGSSMTYHFQEHYTL 753
+T C N G C ++ G TCDC ++Y GP C++ + Y F G ++ YT
Sbjct: 1098 TTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPGTTYIFGKGGALI-----TYTW 1152
Query: 754 SENSSSLVSSLHRDVTLTR-EMITLSFRTTRTPSLLLYV--SSFYEEYLSVILANNGSLQ 810
N D TR + + + F T + ++L+ V +S +YL + + + G++
Sbjct: 1153 PPN----------DRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI-DQGTVG 1201
Query: 811 IRYKLDRHQNPDAFTFDFKN--MADGQLHQVKINREEAVVMVEVN 853
+ + + D T D N ++DG+ H V+ R ++V+
Sbjct: 1202 VIFNV----GTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD 1242
Score = 75.5 bits (184), Expect = 2e-13
Identities = 83/377 (22%), Positives = 152/377 (40%), Gaps = 68/377 (18%)
Query: 521 DKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI----------- 569
D + + +F + +++ P + + T + F+TT +G+ + + G
Sbjct: 488 DVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGGGAGSHSS 547
Query: 570 ---TDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVD 626
D+ +EL + D+G+G ++ S ND +W HV +R+ + S+ V+
Sbjct: 548 AQRADYFAMEL-LDGHLYLLLDMGSGGIKLRASS-RKVNDGEWCHVDFQRDGRKGSISVN 605
Query: 627 QLPQKMQPAPADGHVR-LQLNSQLFIGG----------------TATRQRGFLGCIRSLQ 669
+ P A G L L S+L++GG TA + G++GC+R L
Sbjct: 606 S---RSTPFLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVRDLF 662
Query: 670 LNGVALDLEERATVMP--GVEPGCAGH----CSTYGHLCRNGGRCREKRRGVTCDCAFSA 723
++G + DL A GV P C+ C++ CRNGG CRE CDC +
Sbjct: 663 IDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAP--CRNGGVCREGWNRFICDCIGTG 720
Query: 724 YDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTR 783
+ G C E + GS L +++H + E ++L F + R
Sbjct: 721 FLGRVCEREATVLSYDGSMYM------------KIMLPNAMHTEA----EDVSLRFMSQR 764
Query: 784 TPSLLLYVSSFYEEYLSVILANNGSLQIRYKLD-------RHQNPDAFTFDFKNMADGQL 836
L++ +S + + G +++ LD + P+ F + D +
Sbjct: 765 AYGLMMATTSRESADTLRLELDGGQMKLTVNLDCLRVGCAPSKGPETL-FAGHKLNDNEW 823
Query: 837 HQVKINREEAVVMVEVN 853
H V++ R + + V+
Sbjct: 824 HTVRVVRRGKSLQLSVD 840
Score = 52.0 bits (123), Expect = 3e-06
Identities = 57/240 (23%), Positives = 93/240 (38%), Gaps = 56/240 (23%)
Query: 597 TVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGG--- 653
T+Q TP D++WH V R+ + +L VD + +Q+ S LF+GG
Sbjct: 100 TLQLDTPVADDRWHMVLLTRDARRTALAVD--GEARAAEVRSKRREMQVASDLFVGGIPP 157
Query: 654 ----------TATRQRGFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGH-----CSTY 698
T + F G + +L+L ER + G + G G C+
Sbjct: 158 DVRLSALTLSTVKYEPPFRGLLANLKLG-------ERPPALLGSQ-GLRGATADPLCAPA 209
Query: 699 GHLCRNGGRCREKRRG-VTCDCAFSAYDGPFCSNEI----------------SAYFATGS 741
+ C NGG C G V CDC+ + + G FCS E S F+ G
Sbjct: 210 RNPCANGGLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEGG 269
Query: 742 SMTYHFQEHYTLSENSSSLVSSL-----------HRDVTLTREMITLSFRTTRTPSLLLY 790
+ + + ++ V++ H + + + ITL+FRT + L+L+
Sbjct: 270 AGRGGAGDVHQPTKGKEEFVATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLH 329
Score = 52.0 bits (123), Expect = 3e-06
Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 5/77 (6%)
Query: 202 GFQGCLRLITIGDKAVD--PILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSW 259
G+ GC+R + I ++ D + QGA+G S +C + C +GG C + W
Sbjct: 653 GYVGCVRDLFIDGRSRDLRGLAEAQGAVGV---APFCSRETLKQCASAPCRNGGVCREGW 709
Query: 260 DTFSCDCLGTGYTGETC 276
+ F CDC+GTG+ G C
Sbjct: 710 NRFICDCIGTGFLGRVC 726
Score = 51.2 bits (121), Expect = 4e-06
Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 3/76 (3%)
Query: 202 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 261
GFQGCL + + + D I AL ++ G + C C + G C Q WD
Sbjct: 1061 GFQGCLASVDLNGRLPDLIA---DALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDG 1117
Query: 262 FSCDCLGTGYTGETCH 277
F+CDC T Y G C+
Sbjct: 1118 FTCDCTMTSYGGPVCN 1133
Score = 40.0 bits (92), Expect = 0.010
Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 2/74 (2%)
Query: 547 TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPT-PFN 605
T ++ F+T +G+ + D++ + L++ V ++G+G E V+ FN
Sbjct: 311 TDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGA-VWLVINLGSGAFEALVEPVNGKFN 369
Query: 606 DNQWHHVRAERNVK 619
DN WH VR RN++
Sbjct: 370 DNAWHDVRVTRNLR 383
Score = 40.0 bits (92), Expect = 0.010
Identities = 75/320 (23%), Positives = 115/320 (35%), Gaps = 74/320 (23%)
Query: 541 AFHGELTADVCFFFKTTVSSGVFMENLG--ITDFIRIELRA-PTEVTFSFD---VGNGPC 594
A H E DV F + + G+ M D +R+EL ++T + D VG P
Sbjct: 748 AMHTE-AEDVSLRFMSQRAYGLMMATTSRESADTLRLELDGGQMKLTVNLDCLRVGCAPS 806
Query: 595 E--VTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIG 652
+ T+ + NDN+WH VR R K L VD + + Q A A H+RL+ ++
Sbjct: 807 KGPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEGQMAGA--HMRLEFHN--IET 862
Query: 653 GTATRQR-------GFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNG 705
G T +R F+G + L NG M + G +C
Sbjct: 863 GIMTERRFISVVPSNFIGHLSGLVFNG--------QPYMDQCKDGDITYCEL-------- 906
Query: 706 GRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLH 765
R R + D P S+Y A + Y +S+H
Sbjct: 907 -NARFGLRAIVAD--------PVTFKSRSSYLALATLQAY----------------ASMH 941
Query: 766 RDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFT 825
+ F+TT LLL+ S +++ + L I Y D P
Sbjct: 942 ---------LFFQFKTTAPDGLLLFNSGNGNDFIVIELVKG---YIHYVFDLGNGPSLMK 989
Query: 826 FDF-KNMADGQLHQVKINRE 844
+ K + D Q H V ++R+
Sbjct: 990 GNSDKPVNDNQWHNVVVSRD 1009
Score = 34.7 bits (78), Expect = 0.43
Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 775 ITLSFRTTRTPSLLLYVSSFYE-EYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMAD 833
++ S RT T +LLLY+ + ++L ++L + G L++R+ L + P D +AD
Sbjct: 53 LSFSLRTNATRALLLYLDDGGDCDFLELLLVD-GRLRLRFTLSCAE-PATLQLDTP-VAD 109
Query: 834 GQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKV 879
+ H V + R+ + V+ A+ + S E L +G +
Sbjct: 110 DRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGI 155
Score = 32.7 bits (73), Expect = 1.6
Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 13/107 (12%)
Query: 203 FQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSY--CEHGGECSQ-SW 259
F+G L + +G++ +L QG G+ D C P+ C +GG C+ +
Sbjct: 175 FRGLLANLKLGERP-PALLGSQGLRGATAD---------PLCAPARNPCANGGLCTVLAP 224
Query: 260 DTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 306
CDC TG+ G+ C + AH + G G+G
Sbjct: 225 GEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEGGAG 271
Score = 32.0 bits (71), Expect = 2.8
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
Query: 568 GITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPF-NDNQWHHVRAERNVKGASLQVD 626
G+ D++++ + T V F+VG ++T+ P +D ++H VR R+ A+LQVD
Sbjct: 1186 GLGDYLQLHIDQGT-VGVIFNVGTD--DITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD 1242
Query: 627 QLP-QKMQPAPADGHVRLQLNSQ 648
P + PA + RL + Q
Sbjct: 1243 SWPVNERYPAGNFDNERLAIARQ 1265
>gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]
Length = 1061
Score = 110 bits (276), Expect = 5e-24
Identities = 98/342 (28%), Positives = 149/342 (43%), Gaps = 37/342 (10%)
Query: 529 SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI-TDFIRIELRAPTEVTFSF 587
+F T++SYL + + F FKTT G + N G DFI +EL + + F
Sbjct: 501 TFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILFNSGDGNDFIAVEL-VKGYIHYVF 559
Query: 588 DVGNGPCEVTVQSPTPFNDNQWHHVRAER-NVKGASLQVDQLPQKMQPAPADGHVRLQLN 646
D+GNGP + S P NDNQWH+V R N SL+VD K+ +G L L
Sbjct: 560 DLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVD---TKVVTQVINGAKNLDLK 616
Query: 647 SQLFIGGTA-----------TRQRGFLGCIRSLQLNGVALDLEERATVMPG-VEPGCAGH 694
L++ G A + GF GC+ S+ LNG DL A G +E GC G
Sbjct: 617 GDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGCEGP 676
Query: 695 CST-YGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYF--ATGSSMTYHFQEHY 751
+T C N G C ++ G TCDC+ ++Y G C++ + Y +G + Y + +
Sbjct: 677 STTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILYTWPAND 736
Query: 752 TLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQI 811
S S L T ++ I + R P L ++ E+ ++ N G++ I
Sbjct: 737 RPSTRSDRLAVGFS---TTVKDGILV--RIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDI 791
Query: 812 RYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVN 853
K +R + DG+ H V+ R ++V+
Sbjct: 792 SIKEER-----------TPVNDGKYHVVRFTRNGGNATLQVD 822
Score = 75.1 bits (183), Expect = 3e-13
Identities = 61/249 (24%), Positives = 104/249 (41%), Gaps = 43/249 (17%)
Query: 529 SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI--------------TDFIR 574
+F T +Y+ P ++ + + F F+TT +G+ + G DF
Sbjct: 77 NFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFA 136
Query: 575 IELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQP 634
+EL + D+G+G +V ND +W+HV +R+ + ++ V+ + P
Sbjct: 137 VEL-LDGNLYLLLDMGSGTIKVKATQKKA-NDGEWYHVDIQRDGRSGTISVNS---RRTP 191
Query: 635 APADGHVR-LQLNSQLFIGG---------------TATRQRGFLGCIRSLQLNGVALDLE 678
A G L L +++GG TA G++GCIR L ++G + ++
Sbjct: 192 FTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIR 251
Query: 679 ERATVM--PGVEPGC----AGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNE 732
+ A + GV+ C A C +Y C+N C++ CDC + Y G C E
Sbjct: 252 QLAEMQNAAGVKSSCSRMSAKQCDSYP--CKNNAVCKDGWNRFICDCTGTGYWGRTCERE 309
Query: 733 ISAYFATGS 741
S GS
Sbjct: 310 ASILSYDGS 318
Score = 50.1 bits (118), Expect = 1e-05
Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Query: 202 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 261
GFQGCL + + + D I AL ++ G + C C + G C Q W+
Sbjct: 641 GFQGCLASVDLNGRLPDLI---NDALHRSGQIERGCEGPSTTCQEDSCANQGVCMQQWEG 697
Query: 262 FSCDCLGTGYTGETCH 277
F+CDC T Y+G C+
Sbjct: 698 FTCDCSMTSYSGNQCN 713
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 7/78 (8%)
Query: 202 GFQGCLRLITIG--DKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSY-CEHGGECSQS 258
G+ GC+R + I K + + Q A G ++ ++ + SY C++ C
Sbjct: 233 GYVGCIRDLFIDGRSKNIRQLAEMQNAAG----VKSSCSRMSAKQCDSYPCKNNAVCKDG 288
Query: 259 WDTFSCDCLGTGYTGETC 276
W+ F CDC GTGY G TC
Sbjct: 289 WNRFICDCTGTGYWGRTC 306
Score = 43.1 bits (100), Expect = 0.001
Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 6/123 (4%)
Query: 554 FKTTVSSGVFME---NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWH 610
F TTV G+ + G+ DF+++ + ++ F++G + + TP ND ++H
Sbjct: 749 FSTTVKDGILVRIDSAPGLGDFLQLHIEQG-KIGVVFNIGTVDISIK-EERTPVNDGKYH 806
Query: 611 HVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQL 670
VR RN A+LQVD P +Q+ IGG + R F G + L
Sbjct: 807 VVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGG-KDKGRLFQGQLSGLYY 865
Query: 671 NGV 673
+G+
Sbjct: 866 DGL 868
Score = 38.9 bits (89), Expect = 0.023
Identities = 59/258 (22%), Positives = 91/258 (35%), Gaps = 65/258 (25%)
Query: 597 TVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTAT 656
T+ + NDN+WH VR R K L VD + H RL+ ++ G T
Sbjct: 391 TLYAGQKLNDNEWHTVRVVRRGKSLKLTVDD--DVAEGTMVGDHTRLEFHN--IETGIMT 446
Query: 657 RQR-------GFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCR 709
+R F+G ++SL NG+ Y LC+NG
Sbjct: 447 EKRYISVVPSSFIGHLQSLMFNGL-----------------------LYIDLCKNG---- 479
Query: 710 EKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVT 769
D +C E+ A F + + + T SS L SL
Sbjct: 480 ---------------DIDYC--ELKARFGLRNIIA----DPVTFKTKSSYL--SLATLQA 516
Query: 770 LTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDF- 828
T + F+TT +L+ S ++++V L I Y D P+ +
Sbjct: 517 YTSMHLFFQFKTTSPDGFILFNSGDGNDFIAVELVKG---YIHYVFDLGNGPNVIKGNSD 573
Query: 829 KNMADGQLHQVKINREEA 846
+ + D Q H V I R+ +
Sbjct: 574 RPLNDNQWHNVVITRDNS 591
>gi|33469931 EGF-like, fibronectin type III and laminin G domains
isoform 2 [Homo sapiens]
Length = 775
Score = 73.9 bits (180), Expect = 6e-13
Identities = 87/325 (26%), Positives = 133/325 (40%), Gaps = 46/325 (14%)
Query: 536 YLHFPAFHGELTADVCFFFKTTVSSGVFMENL--GITDFIRIELRAPTEVTFSFDVGNGP 593
YL F F E+T F+ GV + + G DF+ I L A V F FD G+G
Sbjct: 397 YLSFMEF--EIT------FRPDSGDGVLLYSYDTGSKDFLSINL-AGGHVEFRFDCGSGT 447
Query: 594 CEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADG-HVRLQLNSQLFIG 652
++S P WH +R R K LQVD+ QK+ A+G +++ N+ +FIG
Sbjct: 448 G--VLRSEDPLTLGNWHELRVSRTAKNGILQVDK--QKIVEGMAEGGFTQIKCNTDIFIG 503
Query: 653 GTATRQ---------RGFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCR 703
G + F G I+ + LN + ++ T GV A H C
Sbjct: 504 GVPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKHDFT--SGVNVENAAHPCVRAP-CA 560
Query: 704 NGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSS 763
+GG CR ++ G CDC ++G C I + Y +N L
Sbjct: 561 HGGSCRPRKEGYDCDCPL-GFEGLHCQKAI----IEAIEIPQFIGRSYLTYDNPDIL--- 612
Query: 764 LHRDVTLTREMITLSFRTTRTPSLLLYVSSF----YEEYLSVILANNGSLQIRYKLDRHQ 819
+ V+ +R + + F+TT LLL+ +++S+ L +G+L Y L
Sbjct: 613 --KRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGL-RDGALVFSYNLGSGV 669
Query: 820 NPDAFTFDFKNMADGQLHQVKINRE 844
F DG+ H+VK R+
Sbjct: 670 ASIMVNGSFN---DGRWHRVKAVRD 691
Score = 53.1 bits (126), Expect = 1e-06
Identities = 43/138 (31%), Positives = 67/138 (48%), Gaps = 19/138 (13%)
Query: 548 ADVCFFFKTTVSSGVFMENLGI-----TDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPT 602
++V FKTT G+ + +DFI + LR V FS+++G+G + V
Sbjct: 620 SNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALV-FSYNLGSGVASIMVNGS- 677
Query: 603 PFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVR-LQLNSQLFIGGT------A 655
FND +WH V+A R+ + + VD + +P G +R L +N L++GG
Sbjct: 678 -FNDGRWHRVKAVRDGQSGKITVDDYGARTGKSP--GMMRQLNINGALYVGGMKEIALHT 734
Query: 656 TRQ--RGFLGCIRSLQLN 671
RQ RG +GCI L+
Sbjct: 735 NRQYMRGLVGCISHFTLS 752
Score = 37.0 bits (84), Expect = 0.087
Identities = 40/166 (24%), Positives = 63/166 (37%), Gaps = 30/166 (18%)
Query: 585 FSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADG----- 639
F F+ G G + S T WH V R+ LQ++ P G
Sbjct: 215 FRFNCGTGVAIIV--SETKIKLGGWHTVMLYRDGLNGLLQLNN------GTPVTGQSQGQ 266
Query: 640 HVRLQLNSQLFIGGTATR---------QRGFLGCIRSLQLNGVALDLE--ERATVMPGVE 688
+ ++ + L++GG + RGF GC++SL +NG +D+ + G +
Sbjct: 267 YSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGAD 326
Query: 689 PG--CAGHCSTYGHLCRNGGRCRE-KRRGVTCDCAFSAYDGPFCSN 731
G +G C C +GG C K C C + G C +
Sbjct: 327 VGECSSGICDEAS--CIHGGTCTAIKADSYICLCPL-GFKGRHCED 369
Score = 36.2 bits (82), Expect = 0.15
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 5/79 (6%)
Query: 202 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQ-SWD 260
GFQGC++ + + + +D G S D+ S GI D + C HGG C+ D
Sbjct: 296 GFQGCVQSLAVNGRRIDMRPWPLGKALSGADVGECSSGICDE---ASCIHGGTCTAIKAD 352
Query: 261 TFSCDCLGTGYTGETCHSS 279
++ C C G+ G C +
Sbjct: 353 SYICLC-PLGFKGRHCEDA 370
Score = 33.1 bits (74), Expect = 1.3
Identities = 13/39 (33%), Positives = 20/39 (51%), Gaps = 1/39 (2%)
Query: 244 CLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYE 282
C+ + C HGG C + + CDC G+ G C ++ E
Sbjct: 554 CVRAPCAHGGSCRPRKEGYDCDC-PLGFEGLHCQKAIIE 591
>gi|33469929 EGF-like, fibronectin type III and laminin G domains
isoform 1 [Homo sapiens]
Length = 1009
Score = 73.9 bits (180), Expect = 6e-13
Identities = 87/325 (26%), Positives = 133/325 (40%), Gaps = 46/325 (14%)
Query: 536 YLHFPAFHGELTADVCFFFKTTVSSGVFMENL--GITDFIRIELRAPTEVTFSFDVGNGP 593
YL F F E+T F+ GV + + G DF+ I L A V F FD G+G
Sbjct: 631 YLSFMEF--EIT------FRPDSGDGVLLYSYDTGSKDFLSINL-AGGHVEFRFDCGSGT 681
Query: 594 CEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADG-HVRLQLNSQLFIG 652
++S P WH +R R K LQVD+ QK+ A+G +++ N+ +FIG
Sbjct: 682 G--VLRSEDPLTLGNWHELRVSRTAKNGILQVDK--QKIVEGMAEGGFTQIKCNTDIFIG 737
Query: 653 GTATRQ---------RGFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCR 703
G + F G I+ + LN + ++ T GV A H C
Sbjct: 738 GVPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKHDFT--SGVNVENAAHPCVRAP-CA 794
Query: 704 NGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSS 763
+GG CR ++ G CDC ++G C I + Y +N L
Sbjct: 795 HGGSCRPRKEGYDCDCPL-GFEGLHCQKAI----IEAIEIPQFIGRSYLTYDNPDIL--- 846
Query: 764 LHRDVTLTREMITLSFRTTRTPSLLLYVSSF----YEEYLSVILANNGSLQIRYKLDRHQ 819
+ V+ +R + + F+TT LLL+ +++S+ L +G+L Y L
Sbjct: 847 --KRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGL-RDGALVFSYNLGSGV 903
Query: 820 NPDAFTFDFKNMADGQLHQVKINRE 844
F DG+ H+VK R+
Sbjct: 904 ASIMVNGSFN---DGRWHRVKAVRD 925
Score = 53.1 bits (126), Expect = 1e-06
Identities = 43/138 (31%), Positives = 67/138 (48%), Gaps = 19/138 (13%)
Query: 548 ADVCFFFKTTVSSGVFMENLGI-----TDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPT 602
++V FKTT G+ + +DFI + LR V FS+++G+G + V
Sbjct: 854 SNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALV-FSYNLGSGVASIMVNGS- 911
Query: 603 PFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVR-LQLNSQLFIGGT------A 655
FND +WH V+A R+ + + VD + +P G +R L +N L++GG
Sbjct: 912 -FNDGRWHRVKAVRDGQSGKITVDDYGARTGKSP--GMMRQLNINGALYVGGMKEIALHT 968
Query: 656 TRQ--RGFLGCIRSLQLN 671
RQ RG +GCI L+
Sbjct: 969 NRQYMRGLVGCISHFTLS 986
Score = 37.0 bits (84), Expect = 0.087
Identities = 40/166 (24%), Positives = 63/166 (37%), Gaps = 30/166 (18%)
Query: 585 FSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADG----- 639
F F+ G G + S T WH V R+ LQ++ P G
Sbjct: 449 FRFNCGTGVAIIV--SETKIKLGGWHTVMLYRDGLNGLLQLNN------GTPVTGQSQGQ 500
Query: 640 HVRLQLNSQLFIGGTATR---------QRGFLGCIRSLQLNGVALDLE--ERATVMPGVE 688
+ ++ + L++GG + RGF GC++SL +NG +D+ + G +
Sbjct: 501 YSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGAD 560
Query: 689 PG--CAGHCSTYGHLCRNGGRCRE-KRRGVTCDCAFSAYDGPFCSN 731
G +G C C +GG C K C C + G C +
Sbjct: 561 VGECSSGICDEAS--CIHGGTCTAIKADSYICLCPL-GFKGRHCED 603
Score = 36.2 bits (82), Expect = 0.15
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 5/79 (6%)
Query: 202 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQ-SWD 260
GFQGC++ + + + +D G S D+ S GI D + C HGG C+ D
Sbjct: 530 GFQGCVQSLAVNGRRIDMRPWPLGKALSGADVGECSSGICDE---ASCIHGGTCTAIKAD 586
Query: 261 TFSCDCLGTGYTGETCHSS 279
++ C C G+ G C +
Sbjct: 587 SYICLC-PLGFKGRHCEDA 604
Score = 33.1 bits (74), Expect = 1.3
Identities = 13/39 (33%), Positives = 20/39 (51%), Gaps = 1/39 (2%)
Query: 244 CLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYE 282
C+ + C HGG C + + CDC G+ G C ++ E
Sbjct: 788 CVRAPCAHGGSCRPRKEGYDCDC-PLGFEGLHCQKAIIE 825
>gi|33469935 EGF-like, fibronectin type III and laminin G domains
isoform 3 [Homo sapiens]
Length = 375
Score = 73.6 bits (179), Expect = 8e-13
Identities = 78/297 (26%), Positives = 123/297 (41%), Gaps = 36/297 (12%)
Query: 562 VFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGA 621
++ + G DF+ I L A V F FD G+G ++S P WH +R R K
Sbjct: 17 LYSYDTGSKDFLSINL-AGGHVEFRFDCGSGTG--VLRSEDPLTLGNWHELRVSRTAKNG 73
Query: 622 SLQVDQLPQKMQPAPADG-HVRLQLNSQLFIGGTATRQ---------RGFLGCIRSLQLN 671
LQVD+ QK+ A+G +++ N+ +FIGG + F G I+ + LN
Sbjct: 74 ILQVDK--QKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQKIILN 131
Query: 672 GVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSN 731
+ ++ T GV A H C +GG CR ++ G CDC ++G C
Sbjct: 132 DRTIHVKHDFT--SGVNVENAAHPCVRAP-CAHGGSCRPRKEGYDCDCPL-GFEGLHCQK 187
Query: 732 EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYV 791
I + Y +N L + V+ +R + + F+TT LLL+
Sbjct: 188 AI----IEAIEIPQFIGRSYLTYDNPDIL-----KRVSGSRSNVFMRFKTTAKDGLLLWR 238
Query: 792 SSF----YEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINRE 844
+++S+ L +G+L Y L F DG+ H+VK R+
Sbjct: 239 GDSPMRPNSDFISLGL-RDGALVFSYNLGSGVASIMVNGSFN---DGRWHRVKAVRD 291
Score = 53.1 bits (126), Expect = 1e-06
Identities = 43/138 (31%), Positives = 67/138 (48%), Gaps = 19/138 (13%)
Query: 548 ADVCFFFKTTVSSGVFMENLGI-----TDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPT 602
++V FKTT G+ + +DFI + LR V FS+++G+G + V
Sbjct: 220 SNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALV-FSYNLGSGVASIMVNGS- 277
Query: 603 PFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVR-LQLNSQLFIGGT------A 655
FND +WH V+A R+ + + VD + +P G +R L +N L++GG
Sbjct: 278 -FNDGRWHRVKAVRDGQSGKITVDDYGARTGKSP--GMMRQLNINGALYVGGMKEIALHT 334
Query: 656 TRQ--RGFLGCIRSLQLN 671
RQ RG +GCI L+
Sbjct: 335 NRQYMRGLVGCISHFTLS 352
Score = 33.1 bits (74), Expect = 1.3
Identities = 13/39 (33%), Positives = 20/39 (51%), Gaps = 1/39 (2%)
Query: 244 CLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYE 282
C+ + C HGG C + + CDC G+ G C ++ E
Sbjct: 154 CVRAPCAHGGSCRPRKEGYDCDC-PLGFEGLHCQKAIIE 191
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 73.2 bits (178), Expect = 1e-12
Identities = 105/475 (22%), Positives = 183/475 (38%), Gaps = 67/475 (14%)
Query: 440 ETHTSWGGSLPD--AQKCT---CGLEGNCIDS--QYYCNCDAG-RNEWTSDTIVLSQKEH 491
E H + G S+ A C+ CG G CI+S YCNC G + + ++T+ EH
Sbjct: 2597 EGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEH 2656
Query: 492 LPVTQIVM--TDAGQPHSEADYT-LGP--LLCRGDKSFWNSASFNTETSYLHFPAFHGEL 546
P T PH + LG + C S + + + E S++ F +FH
Sbjct: 2657 DPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRK 2716
Query: 547 TADVCFFFKTTVSSGVFM---ENLGIT--DFIRIELRAPTEVTFSFDVGNGPCEVTVQSP 601
+ F+ + G+ ++L DF+ I L + V +++G+ +
Sbjct: 2717 KTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISL-VNSSVQLRYNLGDRTIILETLQK 2775
Query: 602 TPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQR-- 659
N + WH ++A R L +D + + + L N+ +IGG ++
Sbjct: 2776 VTINGSTWHIIKAGRVGAEGYLDLDGI--NVTEKASTKMSSLDTNTDFYIGGVSSLNLVN 2833
Query: 660 ---------GFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCRE 710
GF GCIR + +N L L E C G Y + CRNGG C
Sbjct: 2834 PMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGY-NTCRNGGECTV 2892
Query: 711 KRRGVTCDCAFSAYDGPFCSNEISAY---------------FATGSSMTYHFQEHYTLSE 755
+C C + G C+ +S F+ T + Y ++
Sbjct: 2893 NGTTFSCRC-LPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENK 2951
Query: 756 NSSSLVSSL-----------HRDVTLTREMITLSFRTTRTPSLLLYVSSFYEE---YLSV 801
S S + +R L I+L+F TT+T L++++ E +L++
Sbjct: 2952 TSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAI 3011
Query: 802 ILANNGSLQIRYKL-DRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQS 855
L +N +L+I L +R P +++ + H V + + + ++ +N S
Sbjct: 3012 GL-HNQTLKIAVNLGERISVP--MSYNNGTFCCNKWHHVVVIQNQTLIKAYINNS 3063
Score = 48.5 bits (114), Expect = 3e-05
Identities = 29/79 (36%), Positives = 43/79 (54%), Gaps = 7/79 (8%)
Query: 202 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 261
GFQGC+R + I ++ + L + GA G + C T C + C +GGEC+ + T
Sbjct: 2843 GFQGCIRQVIINNQELQ--LTEFGAKGGSN---VGDCDGT-ACGYNTCRNGGECTVNGTT 2896
Query: 262 FSCDCLGTGYTGETCHSSL 280
FSC CL + G TC+ S+
Sbjct: 2897 FSCRCL-PDWAGNTCNQSV 2914
Score = 43.5 bits (101), Expect = 0.001
Identities = 57/212 (26%), Positives = 85/212 (40%), Gaps = 35/212 (16%)
Query: 543 HGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPT 602
H L ++ FF +G L DF+ + L + V +S+++G+G + +
Sbjct: 2454 HSALQNNLIFF------TGQKGHGLNGDDFLAVGLLNGS-VVYSYNLGSGIASIRSE--- 2503
Query: 603 PFNDNQW-HHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGT------- 654
P N + H V + + L+VD K AP V L + SQ ++GG
Sbjct: 2504 PLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGR-LVGLNVFSQFYVGGYSEYTPDL 2562
Query: 655 ----ATRQRGFLGCIRSLQLNGVALDLEERATVMPGVEPGC--------AGHCSTYGHLC 702
A + GF GCI +LQ+ D R P P A CS C
Sbjct: 2563 LPNGADFKNGFQGCIFTLQVR-TEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMK--C 2619
Query: 703 RNGGRCREKRRGVTCDCAFSAYDGPFCSNEIS 734
NGG C E V C+C + + G FC+ +S
Sbjct: 2620 GNGGTCIESGTSVYCNCT-TGWKGSFCTETVS 2650
Score = 40.4 bits (93), Expect = 0.008
Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 11/74 (14%)
Query: 660 GFLGCIRSLQLNGVALDLEERATVMPGVE----PGCAGHCSTYGHLCRNGGRCREKRRGV 715
GF GCI LQ+N + + A +E P CA H LCRN G C +
Sbjct: 2304 GFRGCILDLQVNNKEFFIIDEARHGKNIENCHVPWCAHH------LCRNNGTCISDNENL 2357
Query: 716 TCDCAFSAYDGPFC 729
C+C Y G C
Sbjct: 2358 FCECP-RLYSGKLC 2370
Score = 32.0 bits (71), Expect = 2.8
Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 244 CLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRG 292
CL C+ G+C + F C C G++G C + E S E K+ G
Sbjct: 894 CLFLSCQDYGDCEDMVNNFRCIC-RPGFSGSLCEIEINECSSEPCKNNG 941
Score = 32.0 bits (71), Expect = 2.8
Identities = 13/38 (34%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Query: 242 DRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSS 279
D CL C H G C + ++CDC +G+ G C ++
Sbjct: 1006 DECLSEPCLHDGVCIDGINHYTCDC-KSGFFGTHCETN 1042
Score = 31.6 bits (70), Expect = 3.6
Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 17/98 (17%)
Query: 199 PLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQS 258
P+ GF+GC+ + + +K ++ + G I++C + C C + G C
Sbjct: 2301 PVYGFRGCILDLQVNNKEF--FIIDEARHGK----NIENCHVP-WCAHHLCRNNGTCISD 2353
Query: 259 WDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSG 296
+ C+C Y+G+ C + SCE NP G
Sbjct: 2354 NENLFCECPRL-YSGKLCQFA----SCE-----NNPCG 2381
Score = 31.2 bits (69), Expect = 4.8
Identities = 10/42 (23%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 241 TDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYE 282
++ C + C++ C+ + ++ C+C +G+TG+ C + E
Sbjct: 772 SNECKMNPCKNNSTCTDLYKSYRCECT-SGWTGQNCSEEINE 812
Score = 30.8 bits (68), Expect = 6.2
Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 7/56 (12%)
Query: 225 GALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSL 280
G G F ++ I+ C S C HG +C + + C C G++G C + L
Sbjct: 1152 GFSGQFCEININECS------SSPCLHGADCEDHINGYVCKC-QPGWSGHHCENEL 1200
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 68.6 bits (166), Expect = 3e-11
Identities = 75/260 (28%), Positives = 104/260 (40%), Gaps = 23/260 (8%)
Query: 568 GITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQ 627
G DF+ + LR + F +D+G G ++S P W V ERN + +L+V
Sbjct: 1686 GKGDFVSLALR-DRRLEFRYDLGKGAA--VIRSREPVTLGAWTRVSLERNGRKGALRVGD 1742
Query: 628 LPQKMQPAPADGHVRLQLNSQLFIGGT---------ATRQRGFLGCIRSLQLNGVALDLE 678
P+ + +P H L L L++GG A GF G I+ + L G L
Sbjct: 1743 GPRVLGESPVP-HTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTP 1801
Query: 679 ERATVMPGVEPGCAGHCSTY--GHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAY 736
E V AGH T GH C NG C + C C + GP C +
Sbjct: 1802 EHVLRQVDVT-SFAGHPCTRASGHPCLNGASCVPREAAYVCLCP-GGFSGPHCEKGLVEK 1859
Query: 737 FATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYE 796
A G T F + T E +++ S + L LS RT T L+L+ E
Sbjct: 1860 SA-GDVDTLAF-DGRTFVEYLNAVTES---EKALQSNHFELSLRTEATQGLVLWSGKATE 1914
Query: 797 EYLSVILA-NNGSLQIRYKL 815
V LA +G LQ+ Y L
Sbjct: 1915 RADYVALAIVDGHLQLSYNL 1934
Score = 43.9 bits (102), Expect = 7e-04
Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 13/114 (11%)
Query: 586 SFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQL 645
S+++G+ P V ++S P N N+W V A R + SLQV +P G +L
Sbjct: 1931 SYNLGSQP--VVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPL-GATQLDT 1987
Query: 646 NSQLFIGG----------TATRQRGFLGCIRSLQLNGVALDLEERATVMPGVEP 689
+ L++GG GF+GC+R + + L L E A P + P
Sbjct: 1988 DGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLEDAVTKPELRP 2041
Score = 34.7 bits (78), Expect = 0.43
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 8/77 (10%)
Query: 202 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 261
G +GC+RL+ + ++ ++ + G + R + CG CLP+ C HGG Q+ +
Sbjct: 1515 GLRGCIRLLDVNNQRLE---LGIGPGAATRGSGVGECG-DHPCLPNPC-HGGAPCQNLEA 1569
Query: 262 --FSCDCLGTGYTGETC 276
F C C G G TC
Sbjct: 1570 GRFHCQC-PPGRVGPTC 1585
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 67.8 bits (164), Expect = 5e-11
Identities = 68/227 (29%), Positives = 96/227 (42%), Gaps = 31/227 (13%)
Query: 532 TETSYLHFPAFHGE--LTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDV 589
T SY+ + E L + +T + V M G TD+ +E+ + + FD
Sbjct: 3835 TGNSYVKYRLTENENKLEMKLTMRLRTYSTHAVVMYARG-TDYSILEIHHG-RLQYKFDC 3892
Query: 590 GNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQL 649
G+GP V+VQS ND QWH V E N A L +DQ+ AP L L++ +
Sbjct: 3893 GSGPGIVSVQS-IQVNDGQWHAVALEVNGNYARLVLDQVHTASGTAPGTLKT-LNLDNYV 3950
Query: 650 FIGGTATRQ-----------RGFLGCIRSLQLNGVALDL----------EERATVMPGVE 688
F GG +Q GF GC+ S+ LNG L L EE V PG
Sbjct: 3951 FFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLNGQELPLNSKPRSYAHIEESVDVSPGCF 4010
Query: 689 PGCAGHCSTYGHLCRNGGRCR-EKRRGVTCDCAFSAYDGPFCSNEIS 734
C++ + C+NGG C G C C+ + Y G C ++
Sbjct: 4011 LTATEDCAS--NPCQNGGVCNPSPAGGYYCKCS-ALYIGTHCEISVN 4054
Score = 37.0 bits (84), Expect = 0.087
Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 8/57 (14%)
Query: 238 CGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNP 294
C ++ C C++GG C S D C C +G+ GE C S + E S GNP
Sbjct: 4087 CQLSPYCKDEPCKNGGTCFDSLDGAVCQC-DSGFRGERCQSDIDECS-------GNP 4135
Score = 32.0 bits (71), Expect = 2.8
Identities = 39/140 (27%), Positives = 63/140 (45%), Gaps = 27/140 (19%)
Query: 741 SSMTYHFQEH--YTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEY 798
SSMT + Y L+EN + L L T+ RT T ++++Y +Y
Sbjct: 3830 SSMTLTGNSYVKYRLTENENKLEMKL-----------TMRLRTYSTHAVVMYARG--TDY 3876
Query: 799 LSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQV--KINREEAVVMVEVNQSA 856
S++ ++G LQ YK D P + + DGQ H V ++N A ++++
Sbjct: 3877 -SILEIHHGRLQ--YKFDCGSGPGIVSVQSIQVNDGQWHAVALEVNGNYARLVLD----- 3928
Query: 857 KKQVILSSGTEFNAVKSLIL 876
QV +SGT +K+L L
Sbjct: 3929 --QVHTASGTAPGTLKTLNL 3946
Score = 30.4 bits (67), Expect = 8.1
Identities = 15/38 (39%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
Query: 244 CLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLY 281
C C +GG C F C C G YTG+ C S Y
Sbjct: 4056 CSSKPCLYGGTCVVDNGGFVCQCRGL-YTGQRCQLSPY 4092
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 56.6 bits (135), Expect = 1e-07
Identities = 46/162 (28%), Positives = 71/162 (43%), Gaps = 29/162 (17%)
Query: 585 FSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVR-- 642
F FD G+G T++ PTP +H V R++ SL V L AP +G +
Sbjct: 3735 FRFDAGSGMA--TIRHPTPLALGHFHTVTLLRSLTQGSLIVGDL------APVNGTSQGK 3786
Query: 643 ---LQLNSQLFIGG--------TATRQRGFLGCIRSLQLNGVALDLEERATVMPGVEPGC 691
L LN +L++GG A GF+GC+R L++ G + + G+
Sbjct: 3787 FQGLDLNEELYLGGYPDYGAIPKAGLSSGFIGCVRELRIQGEEIVFHDLNLTAHGI---- 3842
Query: 692 AGHCST-YGHLCRNGGRCRE-KRRGVTCDCAFSAYDGPFCSN 731
HC T C+NGG+C + + C C + + G C +
Sbjct: 3843 -SHCPTCRDRPCQNGGQCHDSESSSYVCVCP-AGFTGSRCEH 3882
Score = 55.8 bits (133), Expect = 2e-07
Identities = 78/306 (25%), Positives = 118/306 (38%), Gaps = 47/306 (15%)
Query: 450 PDAQKCTCGLEGNCIDSQ---YYCNCDAGRNEWTSDTIVLSQKEHL------PVTQIVMT 500
P + C G C DS+ Y C C AG +T SQ H P V
Sbjct: 3846 PTCRDRPCQNGGQCHDSESSSYVCVCPAG---FTGSRCEHSQALHCHPEACGPDATCVNR 3902
Query: 501 DAGQPHS-EADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAF---HGELTADVCFFFKT 556
G+ ++ L C + + S + SYL PA H EL DV FK
Sbjct: 3903 PDGRGYTCRCHLGRSGLRCEEGVTV-TTPSLSGAGSYLALPALTNTHHELRLDV--EFKP 3959
Query: 557 TVSSGVFMENLG----ITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHV 612
GV + + G + DF+ + + + F +++G+G ++S P +WH V
Sbjct: 3960 LAPDGVLLFSGGKSGPVEDFVSLAM-VGGHLEFRYELGSGLA--VLRSAEPLALGRWHRV 4016
Query: 613 RAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGT--------ATRQRG-FLG 663
AER K SL+V+ ++ +P L L++ L++GG AT F G
Sbjct: 4017 SAERLNKDGSLRVNGGRPVLRSSPGKSQ-GLNLHTLLYLGGVEPSVPLSPATNMSAHFRG 4075
Query: 664 CIRSLQLNGVALDLEERATVMPGV-----EPGCAGHCSTYGHLCRNGGR------CREKR 712
C+ + +NG LDL G+ C +G C G CR+
Sbjct: 4076 CVGEVSVNGKRLDLTYSFLGSQGIGQCYDSSPCERQPCQHGATCMPAGEYEFQCLCRDGF 4135
Query: 713 RGVTCD 718
+G C+
Sbjct: 4136 KGDLCE 4141
Score = 50.4 bits (119), Expect = 8e-06
Identities = 42/137 (30%), Positives = 62/137 (45%), Gaps = 24/137 (17%)
Query: 571 DFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVD--QL 628
DFI + L+ + F + +G+G E + S P ND +WH V A R + S+QVD +L
Sbjct: 4258 DFISLGLQ-DGHLVFRYQLGSG--EARLVSEDPINDGEWHRVTALREGRRGSIQVDGEEL 4314
Query: 629 PQKMQPAPADGHVRLQLNSQLFIGG-----TATRQR---GFLGCIRSLQLNGV------- 673
P P +V + ++IGG T T R G GC+++L L+
Sbjct: 4315 VSGRSPGP---NVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVLHSARPGAPPP 4371
Query: 674 -ALDLEERATVMPGVEP 689
LDL+ RA P
Sbjct: 4372 QPLDLQHRAQAGANTRP 4388
Score = 38.9 bits (89), Expect = 0.023
Identities = 32/108 (29%), Positives = 44/108 (40%), Gaps = 18/108 (16%)
Query: 202 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITD--RCLPSYCEHGGECSQS- 258
GF GC+R + I QG F DL + + GI+ C C++GG+C S
Sbjct: 3815 GFIGCVRELRI-----------QGEEIVFHDLNLTAHGISHCPTCRDRPCQNGGQCHDSE 3863
Query: 259 WDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 306
++ C C G+TG C S Q+ H P DG G
Sbjct: 3864 SSSYVCVC-PAGFTGSRCEHS---QALHCHPEACGPDATCVNRPDGRG 3907
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 55.8 bits (133), Expect = 2e-07
Identities = 62/224 (27%), Positives = 95/224 (42%), Gaps = 33/224 (14%)
Query: 527 SASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFS 586
+ +F + SY+ + A++ T +G+ + G D + +EL V
Sbjct: 1159 TVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYK-GDNDPLALELYQG-HVRLV 1216
Query: 587 FDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQ-LPQ---KMQPAPADGHVR 642
+D + P TV S ND Q+H V + +L VD+ P+ K+Q PA G
Sbjct: 1217 YDSLSSP-PTTVYSVETVNDGQFHSVELVTLNQTLNLVVDKGTPKSLGKLQKQPAVG--- 1272
Query: 643 LQLNSQLFIGG-------TATRQR------GFLGCIRSLQLNGVALDLEERATVMPGVEP 689
+NS L++GG +A RQ GF GCI +++N D + GV P
Sbjct: 1273 --INSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSP 1330
Query: 690 GCAGHCSTYGHLCRNGGRCRE-KRRGVTCDCAFSAYDGPFCSNE 732
GC C+ H G CR ++ V C+C + GP C E
Sbjct: 1331 GCKS-CTVCKH-----GLCRSVEKDSVVCECR-PGWTGPLCDQE 1367
Score = 41.2 bits (95), Expect = 0.005
Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 15/100 (15%)
Query: 195 GCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP-SYCEHGG 253
G PLGGF GC+ + I ++ D F+ L S G++ C + C+HG
Sbjct: 1294 GTDRPLGGFHGCIHEVRINNELQD-----------FKALPPQSLGVSPGCKSCTVCKHGL 1342
Query: 254 ECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHK-HRG 292
S D+ C+C G+TG C C H+ H G
Sbjct: 1343 CRSVEKDSVVCEC-RPGWTGPLCDQEA-RDPCLGHRCHHG 1380
Score = 38.5 bits (88), Expect = 0.030
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 5/54 (9%)
Query: 240 ITDRCLP--SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHR 291
+ D C+P + C+H +C FSC+C+ GY+G+ C + C AHK R
Sbjct: 1034 VIDHCVPELNLCQHEAKCIPLDKGFSCECV-PGYSGKLCETD--NDDCVAHKCR 1084
Score = 35.4 bits (80), Expect = 0.25
Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 7/49 (14%)
Query: 689 PGCAGH-CST-----YGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSN 731
PG +G C T H CR+G +C + G TC C + GPFC +
Sbjct: 1064 PGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCP-QGFSGPFCEH 1111
Score = 32.7 bits (73), Expect = 1.6
Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 6/53 (11%)
Query: 244 CLPSYCEHGGECSQS---WDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN 293
C+ + C+HGG C S D FSC C G+ G+ C + CE + N
Sbjct: 959 CIQNPCQHGGTCHLSDSHKDGFSCSC-PLGFEGQRC--EINPDDCEDNDCENN 1008
Score = 30.4 bits (67), Expect = 8.1
Identities = 11/35 (31%), Positives = 19/35 (54%), Gaps = 1/35 (2%)
Query: 242 DRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETC 276
D C+ C HG +C + + ++C C G++G C
Sbjct: 1076 DDCVAHKCRHGAQCVDTINGYTCTC-PQGFSGPFC 1109
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 53.1 bits (126), Expect = 1e-06
Identities = 41/137 (29%), Positives = 66/137 (48%), Gaps = 18/137 (13%)
Query: 555 KTTVSSGV--FMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHV 612
+T SG+ +M + DF ++LR FS+D+G+G + PT ND QWH +
Sbjct: 2790 RTEAESGLLFYMARINHADFATVQLRNGLPY-FSYDLGSGDTHTMI--PTKINDGQWHKI 2846
Query: 613 RAERNVKGASLQVDQLPQK-MQPAPADGHVRLQLNSQLFIGGT----ATRQRGFL----- 662
+ R+ + L VD + + P AD L + L++GG TR+ G +
Sbjct: 2847 KIMRSKQEGILYVDGASNRTISPKKAD---ILDVVGMLYVGGLPINYTTRRIGPVTYSID 2903
Query: 663 GCIRSLQLNGVALDLEE 679
GC+R+L + DLE+
Sbjct: 2904 GCVRNLHMAEAPADLEQ 2920
Score = 43.1 bits (100), Expect = 0.001
Identities = 48/156 (30%), Positives = 67/156 (42%), Gaps = 23/156 (14%)
Query: 552 FFFKTTVSSGVFMENLGIT----DFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFN-- 605
F F+TT ++GV LGI+ D + IE+ ++ F D G G + P +
Sbjct: 2962 FEFRTTTTTGVL---LGISSQKMDGMGIEM-IDEKLMFHVDNGAGRFTAVYDAGVPGHLC 3017
Query: 606 DNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGG--------TATR 657
D QWH V A + L VD + Q +P N +F+GG T
Sbjct: 3018 DGQWHKVTANKIKHRIELTVDGNQVEAQ-SPNPASTSADTNDPVFVGGFPDDLKQFGLTT 3076
Query: 658 QRGFLGCIRSLQL-NGVALDLE---ERATVMPGVEP 689
F GCIRSL+L G LE +A + GV+P
Sbjct: 3077 SIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQP 3112
Score = 41.6 bits (96), Expect = 0.004
Identities = 66/300 (22%), Positives = 108/300 (36%), Gaps = 49/300 (16%)
Query: 601 PTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQR- 659
P F+D + H V ER ++QVD+ + MQ + + ++ +LF+GG +
Sbjct: 2611 PNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVEQPIEVK---KLFVGGAPPEFQP 2667
Query: 660 -------GFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKR 712
F GCI +L +N V +D R + G H + RE
Sbjct: 2668 SPLRNIPPFEGCIWNLVINSVPMDF-ARPVSFKNADIGRCAH-----------QKLREDE 2715
Query: 713 RGVTC--------DCAFSAYDGPF-------CSNEISAYFATGSSMTYHFQEHYTLSENS 757
G A+ P C+ E GS + + LS NS
Sbjct: 2716 DGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGS-------KQFGLSRNS 2768
Query: 758 SSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDR 817
++ V R I L RT LL Y++ + + NG Y L
Sbjct: 2769 HIAIAFDDTKVK-NRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLG- 2826
Query: 818 HQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILG 877
+ D T + DGQ H++KI R + ++ V+ ++ + + + V L +G
Sbjct: 2827 --SGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVG 2884
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 53.1 bits (126), Expect = 1e-06
Identities = 41/137 (29%), Positives = 66/137 (48%), Gaps = 18/137 (13%)
Query: 555 KTTVSSGV--FMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHV 612
+T SG+ +M + DF ++LR FS+D+G+G + PT ND QWH +
Sbjct: 2794 RTEAESGLLFYMARINHADFATVQLRNGLPY-FSYDLGSGDTHTMI--PTKINDGQWHKI 2850
Query: 613 RAERNVKGASLQVDQLPQK-MQPAPADGHVRLQLNSQLFIGGT----ATRQRGFL----- 662
+ R+ + L VD + + P AD L + L++GG TR+ G +
Sbjct: 2851 KIMRSKQEGILYVDGASNRTISPKKAD---ILDVVGMLYVGGLPINYTTRRIGPVTYSID 2907
Query: 663 GCIRSLQLNGVALDLEE 679
GC+R+L + DLE+
Sbjct: 2908 GCVRNLHMAEAPADLEQ 2924
Score = 43.1 bits (100), Expect = 0.001
Identities = 48/156 (30%), Positives = 67/156 (42%), Gaps = 23/156 (14%)
Query: 552 FFFKTTVSSGVFMENLGIT----DFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFN-- 605
F F+TT ++GV LGI+ D + IE+ ++ F D G G + P +
Sbjct: 2966 FEFRTTTTTGVL---LGISSQKMDGMGIEM-IDEKLMFHVDNGAGRFTAVYDAGVPGHLC 3021
Query: 606 DNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGG--------TATR 657
D QWH V A + L VD + Q +P N +F+GG T
Sbjct: 3022 DGQWHKVTANKIKHRIELTVDGNQVEAQ-SPNPASTSADTNDPVFVGGFPDDLKQFGLTT 3080
Query: 658 QRGFLGCIRSLQL-NGVALDLE---ERATVMPGVEP 689
F GCIRSL+L G LE +A + GV+P
Sbjct: 3081 SIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQP 3116
Score = 41.6 bits (96), Expect = 0.004
Identities = 66/300 (22%), Positives = 108/300 (36%), Gaps = 49/300 (16%)
Query: 601 PTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQR- 659
P F+D + H V ER ++QVD+ + MQ + + ++ +LF+GG +
Sbjct: 2615 PNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVEQPIEVK---KLFVGGAPPEFQP 2671
Query: 660 -------GFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKR 712
F GCI +L +N V +D R + G H + RE
Sbjct: 2672 SPLRNIPPFEGCIWNLVINSVPMDF-ARPVSFKNADIGRCAH-----------QKLREDE 2719
Query: 713 RGVTC--------DCAFSAYDGPF-------CSNEISAYFATGSSMTYHFQEHYTLSENS 757
G A+ P C+ E GS + + LS NS
Sbjct: 2720 DGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGS-------KQFGLSRNS 2772
Query: 758 SSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDR 817
++ V R I L RT LL Y++ + + NG Y L
Sbjct: 2773 HIAIAFDDTKVK-NRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLG- 2830
Query: 818 HQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILG 877
+ D T + DGQ H++KI R + ++ V+ ++ + + + V L +G
Sbjct: 2831 --SGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVG 2888
>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
sapiens]
Length = 3312
Score = 53.1 bits (126), Expect = 1e-06
Identities = 89/391 (22%), Positives = 148/391 (37%), Gaps = 74/391 (18%)
Query: 534 TSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGIT---DFIRIELRAPTEVTFSFDVG 590
+S++ F + F T SG+ N + DF+ +EL A +V ++ G
Sbjct: 1523 SSFVMFRGLRQRFHLTLSLSFATVQQSGLLFYNGRLNEKHDFLALELVAG-QVRLTYSTG 1581
Query: 591 NGPCEVTVQSPTPFNDNQWH--HVRAERNVKGASLQVDQLPQKMQPA-----PADGHVRL 643
V+ P +D QWH H+R + +L Q P K + A D V L
Sbjct: 1582 ESNTVVSPTVPGGLSDGQWHTVHLRYYNKPRTDALGGAQGPSKDKVAVLSVDDCDVAVAL 1641
Query: 644 Q------------------------LNSQLFIGGT-------ATRQRGFLGCIRSLQLNG 672
Q L L +GG + F+GC+R L ++G
Sbjct: 1642 QFGAEIGNYSCAAAGVQTSSKKSLDLTGPLLLGGVPNLPENFPVSHKDFIGCMRDLHIDG 1701
Query: 673 VALDLEERATVMPGVEPGCAG--HCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCS 730
+D+ G GC H G C+N G C E+ +CDC + G C
Sbjct: 1702 RRVDM-AAFVANNGTMAGCQAKLHFCDSGP-CKNSGFCSERWGSFSCDCPV-GFGGKDCQ 1758
Query: 731 NEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTRE-MITLSFRTTRTPSLLL 789
+ + +HF+ + TLS N S D+ ++ + L+FRT T +L+
Sbjct: 1759 LTM--------AHPHHFRGNGTLSWNFGS-------DMAVSVPWYLGLAFRTRATQGVLM 1803
Query: 790 YVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEA--- 846
V + L L + G L + + D ++DG+ H +++ +E
Sbjct: 1804 QVQAGPHSTLLCQL-DRGLLSVTVTRGSGR-ASHLLLDQVTVSDGRWHDLRLELQEEPGG 1861
Query: 847 -----VVMVEVNQSAKKQVILSSGTEFNAVK 872
V+MV ++ S Q ++ G+E +K
Sbjct: 1862 RRGHHVLMVSLDFSL-FQDTMAVGSELQGLK 1891
Score = 41.6 bits (96), Expect = 0.004
Identities = 57/238 (23%), Positives = 93/238 (39%), Gaps = 44/238 (18%)
Query: 652 GGTATRQRGFLGCIRSLQLNGVALDLE-ERATVMPGVEPGCAGHCSTYGHLCRNGGRCRE 710
GG R+ G C+ + G +L+ E +PGV CRNGG C +
Sbjct: 1447 GGACARREGGYTCVCRPRFTGEDCELDTEAGRCVPGV--------------CRNGGTCTD 1492
Query: 711 -KRRGVTCDC-AFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDV 768
G C C A A++GP C E++A SS + L +
Sbjct: 1493 APNGGFRCQCPAGGAFEGPRC--EVAARSFPPSSFV---------------MFRGLRQRF 1535
Query: 769 TLTREMITLSFRTTRTPSLLLYVSSFYE--EYLSVILANNGSLQIRYKLDRHQNPDAFTF 826
LT ++LSF T + LL Y E ++L++ L G +++ Y + T
Sbjct: 1536 HLT---LSLSFATVQQSGLLFYNGRLNEKHDFLALELV-AGQVRLTYSTGESNTVVSPTV 1591
Query: 827 DFKNMADGQLHQVKI---NREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLG 881
++DGQ H V + N+ + +K +V + S + + +L G +G
Sbjct: 1592 P-GGLSDGQWHTVHLRYYNKPRTDALGGAQGPSKDKVAVLSVDDCDVAVALQFGAEIG 1648
Score = 40.0 bits (92), Expect = 0.010
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 14/93 (15%)
Query: 203 FQGCLRLITIGDKAVD--PILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWD 260
F GC+R + I + VD + G + + C C++ G CS+ W
Sbjct: 1690 FIGCMRDLHIDGRRVDMAAFVANNGTMAGCQ-------AKLHFCDSGPCKNSGFCSERWG 1742
Query: 261 TFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN 293
+FSCDC G+ G+ C ++ H RGN
Sbjct: 1743 SFSCDC-PVGFGGKDCQLTM----AHPHHFRGN 1770
Score = 38.9 bits (89), Expect = 0.023
Identities = 28/99 (28%), Positives = 41/99 (41%), Gaps = 7/99 (7%)
Query: 189 GNSSGSGCKSPLGGFQGCLRLITIGDK-AVDPILVQQGALGSFRDLQIDSCGITDRCLPS 247
G GS ++P G GC++ + +G + P L+ S R C +T+ C
Sbjct: 1899 GLPPGSAEEAPQG-LVGCIQGVWLGSTPSGSPALLPP----SHRVNAEPGCVVTNACASG 1953
Query: 248 YCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCE 286
C +C W TFSC C GY G C + C+
Sbjct: 1954 PCPPHADCRDLWQTFSCTC-QPGYYGPGCVDACLLNPCQ 1991
Score = 33.1 bits (74), Expect = 1.3
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 16/75 (21%)
Query: 661 FLGCIRSLQLNGVALDLEERATVMPGVEP----------GCAGH-CST-----YGHLCRN 704
++ C+ L+ + A L +T+ ++P G G C T Y + CRN
Sbjct: 1387 YMKCVSVLRFDSSAPFLASASTLFRPIQPIAGLRCRCPPGFTGDFCETELDLCYSNPCRN 1446
Query: 705 GGRCREKRRGVTCDC 719
GG C + G TC C
Sbjct: 1447 GGACARREGGYTCVC 1461
Score = 32.7 bits (73), Expect = 1.6
Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 4/48 (8%)
Query: 239 GITDRCLPSYCEHGGECSQ---SWDTFSCDCLGTGYTGETCHSSLYEQ 283
G D CL + C++ G C + ++CDC+G GY G C + +Q
Sbjct: 1980 GCVDACLLNPCQNQGSCRHLPGAPHGYTCDCVG-GYFGHHCEHRMDQQ 2026
>gi|33469937 EGF-like, fibronectin type III and laminin G domains
isoform 4 [Homo sapiens]
Length = 152
Score = 52.8 bits (125), Expect = 2e-06
Identities = 42/132 (31%), Positives = 64/132 (48%), Gaps = 19/132 (14%)
Query: 554 FKTTVSSGVFMENLGI-----TDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQ 608
FKTT G+ + +DFI + LR V FS+++G+G + V FND +
Sbjct: 3 FKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALV-FSYNLGSGVASIMVNGS--FNDGR 59
Query: 609 WHHVRAERNVKGASLQVDQLPQKMQPAPADGHVR-LQLNSQLFIGGT------ATRQ--R 659
WH V+A R+ + + VD + +P G +R L +N L++GG RQ R
Sbjct: 60 WHRVKAVRDGQSGKITVDDYGARTGKSP--GMMRQLNINGALYVGGMKEIALHTNRQYMR 117
Query: 660 GFLGCIRSLQLN 671
G +GCI L+
Sbjct: 118 GLVGCISHFTLS 129
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 52.4 bits (124), Expect = 2e-06
Identities = 61/229 (26%), Positives = 86/229 (37%), Gaps = 43/229 (18%)
Query: 527 SASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFS 586
S +F +YL F A++ T +G+ + N G D I +EL V S
Sbjct: 1167 SVNFVDRDTYLQFTDLQNWPRANITLQVSTAEDNGILLYN-GDNDHIAVELYQG-HVRVS 1224
Query: 587 FDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADG---HVRL 643
+D G+ P + T ND Q+H V + +L +D P D H L
Sbjct: 1225 YDPGSYPSSAIYSAET-INDGQFHTVELVAFDQMVNLSIDG----GSPMTMDNFGKHYTL 1279
Query: 644 QLNSQLFIGGTAT-------------RQRGFLGCIRSLQLNGVALDLEERATVMPGVEPG 690
+ L++GG GF GCIR+L +N D + + PGV PG
Sbjct: 1280 NSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNELQDF-TKTQMKPGVVPG 1338
Query: 691 CA---------GHC---STYGHLCRNGGRCREKRRGVTCDCAFSAYDGP 727
C G C +T G +C C G+ CD DGP
Sbjct: 1339 CEPCRKLYCLHGICQPNATPGPMC----HCEAGWVGLHCD---QPADGP 1380
Score = 35.0 bits (79), Expect = 0.33
Identities = 33/155 (21%), Positives = 58/155 (37%), Gaps = 24/155 (15%)
Query: 699 GHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSS 758
G C+NG C ++ C C + GP C +S F + +T +N
Sbjct: 1133 GTECQNGANCVDQGNRPVCQC-LPGFGGPECEKLLSVNFVDRDTYL-----QFTDLQN-- 1184
Query: 759 SLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRH 818
R ITL T +LLY ++++V L +R D
Sbjct: 1185 -----------WPRANITLQVSTAEDNGILLYNGD--NDHIAVELYQG---HVRVSYDPG 1228
Query: 819 QNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVN 853
P + + + + DGQ H V++ + +V + ++
Sbjct: 1229 SYPSSAIYSAETINDGQFHTVELVAFDQMVNLSID 1263
Score = 32.7 bits (73), Expect = 1.6
Identities = 14/42 (33%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Query: 236 DSCGIT-DRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETC 276
D+C D C C++G +C +++SC C GY+G+ C
Sbjct: 1078 DNCSENQDDCRDHRCQNGAQCMDEVNSYSCLC-AEGYSGQLC 1118
Score = 32.0 bits (71), Expect = 2.8
Identities = 14/41 (34%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 237 SCGI-TDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETC 276
+CG+ TD C+ C +GG C ++C C Y G+ C
Sbjct: 1001 TCGVNTDDCVDHACANGGVCVDGVGNYTCQC-PLQYEGKAC 1040
Score = 32.0 bits (71), Expect = 2.8
Identities = 15/52 (28%), Positives = 25/52 (48%), Gaps = 5/52 (9%)
Query: 240 ITDRCLPSY--CEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHK 289
+ D C P C+H +C + D C+C+ GY G+ C + + C H+
Sbjct: 1043 LVDLCSPDLNPCQHEAQCVGTPDGPRCECM-PGYAGDNCSEN--QDDCRDHR 1091
Score = 30.4 bits (67), Expect = 8.1
Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 4/47 (8%)
Query: 242 DRCLPSYCEHGGEC-SQSWDTFSCDCLGTGYTGETCHSSLYEQSCEA 287
D CL S C++ G C + + + C C +GY G C SL SC +
Sbjct: 927 DLCLSSPCQNQGTCHNDPLEVYRCAC-PSGYKGRDCEVSL--DSCSS 970
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,082,566
Number of Sequences: 37866
Number of extensions: 2181985
Number of successful extensions: 10809
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 196
Number of HSP's that attempted gapping in prelim test: 9719
Number of HSP's gapped (non-prelim): 1166
length of query: 944
length of database: 18,247,518
effective HSP length: 112
effective length of query: 832
effective length of database: 14,006,526
effective search space: 11653429632
effective search space used: 11653429632
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.