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Search of human proteins with 239743724
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo
sapiens]
(1415 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 2805 0.0
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 2805 0.0
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 2354 0.0
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 2274 0.0
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 1942 0.0
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 1926 0.0
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 527 e-149
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 369 e-102
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 369 e-101
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 368 e-101
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 367 e-101
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 353 6e-97
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 353 6e-97
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 283 8e-76
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 283 8e-76
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo... 282 1e-75
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 271 3e-72
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens] 253 1e-66
gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo... 248 3e-65
gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo ... 243 9e-64
gi|52856430 protein expressed in prostate, ovary, testis, and pl... 241 3e-63
gi|209977003 ANKRD26-like family C, member 3 [Homo sapiens] 241 3e-63
gi|52856434 POTE ankyrin domain family, member G [Homo sapiens] 240 6e-63
gi|239741769 PREDICTED: similar to protein expressed in prostate... 240 6e-63
gi|224282147 prostate-specific P704P [Homo sapiens] 240 8e-63
gi|134133226 protein expressed in prostate, ovary, testis, and p... 239 1e-62
gi|153791352 prostate, ovary, testis expressed protein on chromo... 239 2e-62
gi|113413200 PREDICTED: similar to protein expressed in prostate... 238 2e-62
gi|88953571 PREDICTED: similar to protein expressed in prostate,... 238 2e-62
gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 236 1e-61
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 2805 bits (7272), Expect = 0.0
Identities = 1415/1415 (100%), Positives = 1415/1415 (100%)
Query: 1 MSPWLRPSQAVYPAAAAPGQEPTPQSHPRWLRRAPVSGPDLSSEEERVGSQGQAGPQAGR 60
MSPWLRPSQAVYPAAAAPGQEPTPQSHPRWLRRAPVSGPDLSSEEERVGSQGQAGPQAGR
Sbjct: 1 MSPWLRPSQAVYPAAAAPGQEPTPQSHPRWLRRAPVSGPDLSSEEERVGSQGQAGPQAGR 60
Query: 61 DALLGFRDVPREPRRTRKPATRAPVLQVPPAGHEGLGAASGVPAVATMRKLFSFGRRLGQ 120
DALLGFRDVPREPRRTRKPATRAPVLQVPPAGHEGLGAASGVPAVATMRKLFSFGRRLGQ
Sbjct: 61 DALLGFRDVPREPRRTRKPATRAPVLQVPPAGHEGLGAASGVPAVATMRKLFSFGRRLGQ 120
Query: 121 ALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLH 180
ALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLH
Sbjct: 121 ALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLH 180
Query: 181 LACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIY 240
LACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIY
Sbjct: 181 LACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIY 240
Query: 241 GNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANI 300
GNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANI
Sbjct: 241 GNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANI 300
Query: 301 HAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQIL 360
HAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQIL
Sbjct: 301 HAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQIL 360
Query: 361 EHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQD 420
EHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQD
Sbjct: 361 EHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQD 420
Query: 421 SQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSV 480
SQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSV
Sbjct: 421 SQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSV 480
Query: 481 RLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEY 540
RLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEY
Sbjct: 481 RLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEY 540
Query: 541 NEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET 600
NEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET
Sbjct: 541 NEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET 600
Query: 601 RDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELEN 660
RDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELEN
Sbjct: 601 RDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELEN 660
Query: 661 LLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKE 720
LLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKE
Sbjct: 661 LLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKE 720
Query: 721 KAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKH 780
KAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKH
Sbjct: 721 KAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKH 780
Query: 781 EEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLN 840
EEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLN
Sbjct: 781 EEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLN 840
Query: 841 TDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEK 900
TDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEK
Sbjct: 841 TDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEK 900
Query: 901 DKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLE 960
DKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLE
Sbjct: 901 DKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLE 960
Query: 961 QLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKLM 1020
QLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKLM
Sbjct: 961 QLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKLM 1020
Query: 1021 KSDKKIAVISTKLFTEKQRMKYFLSTLPTRPEPELPCVENLNSIELNRKYIPKTAIRIPT 1080
KSDKKIAVISTKLFTEKQRMKYFLSTLPTRPEPELPCVENLNSIELNRKYIPKTAIRIPT
Sbjct: 1021 KSDKKIAVISTKLFTEKQRMKYFLSTLPTRPEPELPCVENLNSIELNRKYIPKTAIRIPT 1080
Query: 1081 SNPQTSNNCKNFLTEVLLCXALAPVYFLLXNPLHCLADLQLYTVPGFHLERVPALSALLG 1140
SNPQTSNNCKNFLTEVLLC ALAPVYFLL NPLHCLADLQLYTVPGFHLERVPALSALLG
Sbjct: 1081 SNPQTSNNCKNFLTEVLLCXALAPVYFLLXNPLHCLADLQLYTVPGFHLERVPALSALLG 1140
Query: 1141 TPPLSASPGPPSVEREEIGEHLWEALILALGPGGDSDEDLGAPVSGAARPGQRSKTNKHT 1200
TPPLSASPGPPSVEREEIGEHLWEALILALGPGGDSDEDLGAPVSGAARPGQRSKTNKHT
Sbjct: 1141 TPPLSASPGPPSVEREEIGEHLWEALILALGPGGDSDEDLGAPVSGAARPGQRSKTNKHT 1200
Query: 1201 HMYTHTRIHKHNACTHVSSGDRGHRLWALLTQAGSCCGGLCHPTMSLLLSPHRLCVVEQL 1260
HMYTHTRIHKHNACTHVSSGDRGHRLWALLTQAGSCCGGLCHPTMSLLLSPHRLCVVEQL
Sbjct: 1201 HMYTHTRIHKHNACTHVSSGDRGHRLWALLTQAGSCCGGLCHPTMSLLLSPHRLCVVEQL 1260
Query: 1261 ETRSSLCEWLCMKDCFLGERHISTQLTDRTQQFHSASPLDTPRTXQDNPIMALSPGPVSL 1320
ETRSSLCEWLCMKDCFLGERHISTQLTDRTQQFHSASPLDTPRT QDNPIMALSPGPVSL
Sbjct: 1261 ETRSSLCEWLCMKDCFLGERHISTQLTDRTQQFHSASPLDTPRTXQDNPIMALSPGPVSL 1320
Query: 1321 RDNQDAGPETTALLDAFNTVGELFANQPSQELDPVMDLLVLSLGHQVIILDIIHIHKEAL 1380
RDNQDAGPETTALLDAFNTVGELFANQPSQELDPVMDLLVLSLGHQVIILDIIHIHKEAL
Sbjct: 1321 RDNQDAGPETTALLDAFNTVGELFANQPSQELDPVMDLLVLSLGHQVIILDIIHIHKEAL 1380
Query: 1381 TKVMESRQHVAEGKTEMQRLMTSESQEQDFFGHCG 1415
TKVMESRQHVAEGKTEMQRLMTSESQEQDFFGHCG
Sbjct: 1381 TKVMESRQHVAEGKTEMQRLMTSESQEQDFFGHCG 1415
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 2805 bits (7272), Expect = 0.0
Identities = 1415/1415 (100%), Positives = 1415/1415 (100%)
Query: 1 MSPWLRPSQAVYPAAAAPGQEPTPQSHPRWLRRAPVSGPDLSSEEERVGSQGQAGPQAGR 60
MSPWLRPSQAVYPAAAAPGQEPTPQSHPRWLRRAPVSGPDLSSEEERVGSQGQAGPQAGR
Sbjct: 1 MSPWLRPSQAVYPAAAAPGQEPTPQSHPRWLRRAPVSGPDLSSEEERVGSQGQAGPQAGR 60
Query: 61 DALLGFRDVPREPRRTRKPATRAPVLQVPPAGHEGLGAASGVPAVATMRKLFSFGRRLGQ 120
DALLGFRDVPREPRRTRKPATRAPVLQVPPAGHEGLGAASGVPAVATMRKLFSFGRRLGQ
Sbjct: 61 DALLGFRDVPREPRRTRKPATRAPVLQVPPAGHEGLGAASGVPAVATMRKLFSFGRRLGQ 120
Query: 121 ALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLH 180
ALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLH
Sbjct: 121 ALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLH 180
Query: 181 LACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIY 240
LACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIY
Sbjct: 181 LACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIY 240
Query: 241 GNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANI 300
GNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANI
Sbjct: 241 GNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANI 300
Query: 301 HAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQIL 360
HAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQIL
Sbjct: 301 HAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQIL 360
Query: 361 EHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQD 420
EHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQD
Sbjct: 361 EHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQD 420
Query: 421 SQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSV 480
SQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSV
Sbjct: 421 SQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSV 480
Query: 481 RLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEY 540
RLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEY
Sbjct: 481 RLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEY 540
Query: 541 NEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET 600
NEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET
Sbjct: 541 NEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET 600
Query: 601 RDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELEN 660
RDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELEN
Sbjct: 601 RDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELEN 660
Query: 661 LLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKE 720
LLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKE
Sbjct: 661 LLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKE 720
Query: 721 KAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKH 780
KAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKH
Sbjct: 721 KAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKH 780
Query: 781 EEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLN 840
EEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLN
Sbjct: 781 EEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLN 840
Query: 841 TDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEK 900
TDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEK
Sbjct: 841 TDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEK 900
Query: 901 DKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLE 960
DKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLE
Sbjct: 901 DKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLE 960
Query: 961 QLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKLM 1020
QLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKLM
Sbjct: 961 QLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKLM 1020
Query: 1021 KSDKKIAVISTKLFTEKQRMKYFLSTLPTRPEPELPCVENLNSIELNRKYIPKTAIRIPT 1080
KSDKKIAVISTKLFTEKQRMKYFLSTLPTRPEPELPCVENLNSIELNRKYIPKTAIRIPT
Sbjct: 1021 KSDKKIAVISTKLFTEKQRMKYFLSTLPTRPEPELPCVENLNSIELNRKYIPKTAIRIPT 1080
Query: 1081 SNPQTSNNCKNFLTEVLLCXALAPVYFLLXNPLHCLADLQLYTVPGFHLERVPALSALLG 1140
SNPQTSNNCKNFLTEVLLC ALAPVYFLL NPLHCLADLQLYTVPGFHLERVPALSALLG
Sbjct: 1081 SNPQTSNNCKNFLTEVLLCXALAPVYFLLXNPLHCLADLQLYTVPGFHLERVPALSALLG 1140
Query: 1141 TPPLSASPGPPSVEREEIGEHLWEALILALGPGGDSDEDLGAPVSGAARPGQRSKTNKHT 1200
TPPLSASPGPPSVEREEIGEHLWEALILALGPGGDSDEDLGAPVSGAARPGQRSKTNKHT
Sbjct: 1141 TPPLSASPGPPSVEREEIGEHLWEALILALGPGGDSDEDLGAPVSGAARPGQRSKTNKHT 1200
Query: 1201 HMYTHTRIHKHNACTHVSSGDRGHRLWALLTQAGSCCGGLCHPTMSLLLSPHRLCVVEQL 1260
HMYTHTRIHKHNACTHVSSGDRGHRLWALLTQAGSCCGGLCHPTMSLLLSPHRLCVVEQL
Sbjct: 1201 HMYTHTRIHKHNACTHVSSGDRGHRLWALLTQAGSCCGGLCHPTMSLLLSPHRLCVVEQL 1260
Query: 1261 ETRSSLCEWLCMKDCFLGERHISTQLTDRTQQFHSASPLDTPRTXQDNPIMALSPGPVSL 1320
ETRSSLCEWLCMKDCFLGERHISTQLTDRTQQFHSASPLDTPRT QDNPIMALSPGPVSL
Sbjct: 1261 ETRSSLCEWLCMKDCFLGERHISTQLTDRTQQFHSASPLDTPRTXQDNPIMALSPGPVSL 1320
Query: 1321 RDNQDAGPETTALLDAFNTVGELFANQPSQELDPVMDLLVLSLGHQVIILDIIHIHKEAL 1380
RDNQDAGPETTALLDAFNTVGELFANQPSQELDPVMDLLVLSLGHQVIILDIIHIHKEAL
Sbjct: 1321 RDNQDAGPETTALLDAFNTVGELFANQPSQELDPVMDLLVLSLGHQVIILDIIHIHKEAL 1380
Query: 1381 TKVMESRQHVAEGKTEMQRLMTSESQEQDFFGHCG 1415
TKVMESRQHVAEGKTEMQRLMTSESQEQDFFGHCG
Sbjct: 1381 TKVMESRQHVAEGKTEMQRLMTSESQEQDFFGHCG 1415
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 2354 bits (6101), Expect = 0.0
Identities = 1226/1424 (86%), Positives = 1273/1424 (89%), Gaps = 70/1424 (4%)
Query: 1 MSPWLRPSQAVYPAAAAPGQEPTPQSHPRWLRRAPVSGPDLSSEEERVGSQGQAGPQAGR 60
MSPWLRPSQAV PAAAAPGQEPT P P SGPDLSSE+ R GS GQAG R
Sbjct: 1 MSPWLRPSQAVCPAAAAPGQEPTLSPIPA---DGPWSGPDLSSEK-RGGSHGQAG----R 52
Query: 61 DALLGFRDVPREPRRTRKPATRAPVLQVPPAGHEGLGAASGVPAVATMRKLFSFGRRLGQ 120
DA L F +VPR+PRRTRKPA P LQ P AGH A SGV AVATMRKL SFGRRLGQ
Sbjct: 53 DARLRFWNVPRQPRRTRKPAAPEPELQSPSAGHASSRAPSGVRAVATMRKLLSFGRRLGQ 112
Query: 121 ALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLH 180
ALLSSMDQEYAG GY IRDWELRKIHRAAIKGDAAEVE CLTRRFRDLD RD+KDRTVLH
Sbjct: 113 ALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLH 172
Query: 181 LACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIY 240
LACAHGRVQVVTLLL R+CQI+ICDRLNRTPLMKAVH QEEACAI+LL+ GANPNI+DIY
Sbjct: 173 LACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIY 232
Query: 241 GNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANI 300
GNTALHYAVYN+GTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANI
Sbjct: 233 GNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANI 292
Query: 301 HAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQIL 360
HAVDNFKRTALILAVQHNLSSIVTLLLQQNI ISSQDMFGQTAEDYA C DLRSI+QQIL
Sbjct: 293 HAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQIL 352
Query: 361 EHKNKMLKNHLRNDNQETAAMKPANLKKRKER---------AKAEHNLKVASEEKQERLQ 411
EHKNKMLKNHLRNDNQETAAMKP NLKKRK+R AKAEHNLKVASEEKQERL+
Sbjct: 353 EHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLE 412
Query: 412 RSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITE 471
RSENKQPQDSQSYGKKKD M+GNFMLK+DIAMLKEELYAIKNDSLRKEKKYIQEIKSITE
Sbjct: 413 RSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITE 472
Query: 472 INANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHS 531
INANFEKSVRLNE+MITK VA+YSQQLNDLKAENARLNS+LEKEKHNKERLEAEVESLHS
Sbjct: 473 INANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHS 532
Query: 532 SLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFN 591
+LATAINEYNEI+ERKDLELVLWRADDVSRHE MGSNISQLTDKNELLTEQVHKARVKFN
Sbjct: 533 NLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFN 592
Query: 592 TLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEE 651
TLKGKLRETRDALREKTLAL SVQLDL+QAQHRIKEMKQMHPNGEAKESQSIGKQNS EE
Sbjct: 593 TLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEE 652
Query: 652 RIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYLK 711
RIRQ+ELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELM EYNYLK
Sbjct: 653 RIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLK 712
Query: 712 EKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQ 771
EKLLQ EKEKAEREVIVREFQEELVDHLK FS+SESPLEGTSHCHINL+ETWTSKKKLFQ
Sbjct: 713 EKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQ 772
Query: 772 VEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANE 831
VEIQPEEKHEEFRK+FELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANE
Sbjct: 773 VEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANE 832
Query: 832 DFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNV 891
DFSCHGDLNTDQLKMDILFKKLKQKF+DL+AEKEAVSS+CVNLAKDNEVLHQELLSM V
Sbjct: 833 DFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKV 892
Query: 892 QEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQK 951
QEKCEKLEKDKKMLEE+VLNLKTHMEKDMVELGK+QEYKSELDERA+Q IEKLEEIHLQK
Sbjct: 893 QEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQK 952
Query: 952 QAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKA 1011
QAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYE+VTTELEE+KEAFA A+KA
Sbjct: 953 QAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTELEEYKEAFAVALKA 1012
Query: 1012 NNSMSKKLMKSDKKIAVISTKLFTEKQRMKYFLSTLPTRPEPELPCVENLNSIELNRKYI 1071
N+SMS+K+ KSDKKIAVISTKLF EK+RM+YFLSTLP RP+PELPCVENLNSIELNRKYI
Sbjct: 1013 NSSMSEKITKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCVENLNSIELNRKYI 1072
Query: 1072 PKTAIRIPTSNPQTSNNCKNFLTEVLLCXALAPVYFLLXNPLHCLADLQLYTVPGFHLER 1131
PK AIRIPTSNPQTSNNCKN LTE+LL ALAP+YFLL NPLHCL DLQLYT PGFHLER
Sbjct: 1073 PKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLLXNPLHCLGDLQLYTRPGFHLER 1132
Query: 1132 VPALSALLGTPPLSASPGPPSVEREEIGEHLWEALILALGPGGDSDEDLGAPVSGAARPG 1191
VPALSALLG PPLSAS GPP VER EIGEHLWEALILALGPGGDSDEDLG+ G P
Sbjct: 1133 VPALSALLGAPPLSASLGPPLVERAEIGEHLWEALILALGPGGDSDEDLGSCCGGLCHP- 1191
Query: 1192 QRSKTNKHTHMYTHTRIHKHNACTHVSSGDRGHRLWALLTQAGSCCGGLCHPTMSLLLSP 1251
TMSLLLSP
Sbjct: 1192 ----------------------------------------------------TMSLLLSP 1199
Query: 1252 HRLCVVEQLETRSSLCEWLCMKDCFLGERHISTQLTDRTQQFHSASPLDTPRTXQDNPIM 1311
HRLCV+EQLET SSLCEWLC+KDCFLGE HISTQLT +TQQFHSASPLDTPRT QDNPIM
Sbjct: 1200 HRLCVLEQLETHSSLCEWLCVKDCFLGEMHISTQLTAQTQQFHSASPLDTPRTXQDNPIM 1259
Query: 1312 ALSPGPVSLRDNQDAGPETTALLDAFNTVGELFANQPSQELDPVMDLLVLSLGHQVIILD 1371
ALSPGPV L DNQ AGPETTALLDAFNTVGEL ANQP QELDPVMDLLVLS GHQV I D
Sbjct: 1260 ALSPGPVWLHDNQHAGPETTALLDAFNTVGELXANQPIQELDPVMDLLVLSQGHQVNIPD 1319
Query: 1372 IIHIHKEALTKVMESRQHVAEGKTEMQRLMTSESQEQDFFGHCG 1415
IIHIHKEALTKVMESRQHVAEGKTE+QRLM SESQEQDFFGHCG
Sbjct: 1320 IIHIHKEALTKVMESRQHVAEGKTEVQRLMMSESQEQDFFGHCG 1363
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 2274 bits (5893), Expect = 0.0
Identities = 1202/1453 (82%), Positives = 1250/1453 (86%), Gaps = 125/1453 (8%)
Query: 1 MSPWLRPSQAVYPAAAAPGQEPTPQSHPRWLRRAPVSGPDLSSEEERVGSQGQAGPQAGR 60
MSPWLRPSQAV PAAAAPGQEPT P P SGPDLSSE+ R GS GQAG R
Sbjct: 1 MSPWLRPSQAVCPAAAAPGQEPTLSPIPA---DGPWSGPDLSSEK-RGGSHGQAG----R 52
Query: 61 DALLGFRDVPREPRRTRKPATRAPVLQVPPAGHEGLGAASGVPA---------------- 104
DA L FR+VPR+PRRTRKPA P LQ P AGH A SGV A
Sbjct: 53 DARLRFRNVPRQPRRTRKPAAPEPELQSPSAGHASSRAPSGVRAGAELGRRLRVSLLKAV 112
Query: 105 -------------VATMRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIK 151
VATMRKL SFGRRLGQALLSSMDQEYAG GY IRDWELRKIHRAAIK
Sbjct: 113 VDRAGSRILSYIAVATMRKLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIK 172
Query: 152 GDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTP 211
GDAAEVE CLTRRFRDLD RD+KDRTVLHLACAHGRVQVVTLLL R+CQI+ICDRLNRTP
Sbjct: 173 GDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTP 232
Query: 212 LMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALN 271
LMKAVH QEEACAI+LL+ GANPNI+DIYGNTALHYAVYN+GTSLAERLLSHHANIEALN
Sbjct: 233 LMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALN 292
Query: 272 KEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNI 331
KEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNI
Sbjct: 293 KEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNI 352
Query: 332 RISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKE 391
ISSQDMFGQTAEDYA C DLRSI+QQILEHKNKMLKNHLRNDNQETAAMKP NLKKRK+
Sbjct: 353 HISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKK 412
Query: 392 R---------AKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIA 442
R AKAEHNLKVASEEKQERL+RSENKQPQDSQSYGKKKD M+GNFMLK+DIA
Sbjct: 413 RKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIA 472
Query: 443 MLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLK 502
MLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNE+MITK VA+YSQQLNDLK
Sbjct: 473 MLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLK 532
Query: 503 AENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDVSRH 562
AENARLNS+LEKEKHNKERLEAEVESLHS+LATAINEYNEI+ERKDLELVLWRADDVSRH
Sbjct: 533 AENARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRH 592
Query: 563 EKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQ 622
E MGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLAL SVQLDL+QAQ
Sbjct: 593 ETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQ 652
Query: 623 HRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVIN 682
HRIKEMKQMHPNGEAKESQSIGKQNS EERIRQ+ELENLLLERQLEDARKEGDNKEIVIN
Sbjct: 653 HRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVIN 712
Query: 683 IHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTF 742
IHRDCLENGKEDLLEERNKELM EYNYLKEKLLQ EKEKAEREVIVREFQEELVDHLK F
Sbjct: 713 IHRDCLENGKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKF 772
Query: 743 SISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRK 802
S+SESPLEGTSHCHINL+ETWTSKKKLFQVEIQPEEKHEEFRK+FELISLLNYTADQIRK
Sbjct: 773 SMSESPLEGTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRK 832
Query: 803 KNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVA 862
KNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKF+DL+A
Sbjct: 833 KNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMA 892
Query: 863 EKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVE 922
EKEAVSS+CVNLAKDNEVLHQELLSM VQEKCEKLEKDKKMLEE+VLNLKTHMEKDMVE
Sbjct: 893 EKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVE 952
Query: 923 LGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVEC 982
LGK+QEYKSELDERA+Q IEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVEC
Sbjct: 953 LGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVEC 1012
Query: 983 KFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFTEKQRMKY 1042
KFSKMKTAYE+VTTELEE+KEAFA A+KAN+SMS+K+ KSDKKIAVISTKLF EK+RM+Y
Sbjct: 1013 KFSKMKTAYEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEY 1072
Query: 1043 FLSTLPTRPEPELPCVENLNSIELNRKYIPKTAIRIPTSNPQTSNNCKNFLTEVLLCXAL 1102
FLSTLP RP+PELPCVENLNSIELNRKYIPK AIRIPTSNPQTSNNCKN LTE+LL AL
Sbjct: 1073 FLSTLPMRPDPELPCVENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWAL 1132
Query: 1103 APVYFLLXNPLHCLADLQLYTVPGFHLERVPALSALLGTPPLSASPGPPSVEREEIGEHL 1162
AP+YFLL NP L+G P A GPPSVEREEIGEHL
Sbjct: 1133 APIYFLLXNP-------------------------LMG-PEGLAGEGPPSVEREEIGEHL 1166
Query: 1163 WEALILALGPGGDSDEDLGAPVSGAARPGQRSKTNKHTHMYTHTRIHKHNACTHVSSGDR 1222
WEALILALGPGGDSDEDLG+ G P
Sbjct: 1167 WEALILALGPGGDSDEDLGSCCGGLCHP-------------------------------- 1194
Query: 1223 GHRLWALLTQAGSCCGGLCHPTMSLLLSPHRLCVVEQLETRSSLCEWLCMKDCFLGERHI 1282
TMSLLLSPHRLCV+EQLET SSLCEWLC+KDCFLGE HI
Sbjct: 1195 ---------------------TMSLLLSPHRLCVLEQLETHSSLCEWLCVKDCFLGEMHI 1233
Query: 1283 STQLTDRTQQFHSASPLDTPRTXQDNPIMALSPGPVSLRDNQDAGPETTALLDAFNTVGE 1342
STQLT +TQQFHSASPLDTPRT QDNPIMALSPGPV L DNQDAGPETTALLDAFNTVGE
Sbjct: 1234 STQLTAQTQQFHSASPLDTPRTXQDNPIMALSPGPVWLHDNQDAGPETTALLDAFNTVGE 1293
Query: 1343 LFANQPSQELDPVMDLLVLSLGHQVIILDIIHIHKEALTKVMESRQHVAEGKTEMQRLMT 1402
L ANQP QELDPVMDLLVLS GHQV I DIIHIHKEALTKVMESRQHVAEGKTE+QRLM
Sbjct: 1294 LXANQPIQELDPVMDLLVLSQGHQVNIPDIIHIHKEALTKVMESRQHVAEGKTEVQRLMM 1353
Query: 1403 SESQEQDFFGHCG 1415
SESQEQDFFGHCG
Sbjct: 1354 SESQEQDFFGHCG 1366
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 1942 bits (5032), Expect = 0.0
Identities = 991/1002 (98%), Positives = 996/1002 (99%)
Query: 108 MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRD 167
MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRD
Sbjct: 1 MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRD 60
Query: 168 LDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVL 227
LDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVL
Sbjct: 61 LDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVL 120
Query: 228 LECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 287
LECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ
Sbjct: 121 LECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 180
Query: 288 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA 347
HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA
Sbjct: 181 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA 240
Query: 348 LCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ 407
LCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ
Sbjct: 241 LCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ 300
Query: 408 ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK 467
ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK
Sbjct: 301 ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK 360
Query: 468 SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE 527
SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE
Sbjct: 361 SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE 420
Query: 528 SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKAR 587
SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKAR
Sbjct: 421 SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKAR 480
Query: 588 VKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQN 647
VKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQN
Sbjct: 481 VKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQN 540
Query: 648 SLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEY 707
SLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEY
Sbjct: 541 SLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEY 600
Query: 708 NYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKK 767
NYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKK
Sbjct: 601 NYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKK 660
Query: 768 KLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNA 827
KLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNA
Sbjct: 661 KLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNA 720
Query: 828 FANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLS 887
FANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLS
Sbjct: 721 FANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLS 780
Query: 888 MRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEI 947
MRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEI
Sbjct: 781 MRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEI 840
Query: 948 HLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAG 1007
HLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAG
Sbjct: 841 HLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAG 900
Query: 1008 AVKANNSMSKKLMKSDKKIAVISTKLFTEKQRMKYFLSTLPTRPEPELPCVENLNSIELN 1067
AVKANNSMSKKLMKSDKKIAVISTKLF EK+RM+YFLSTLP RP+PELPCVENLNSIELN
Sbjct: 901 AVKANNSMSKKLMKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCVENLNSIELN 960
Query: 1068 RKYIPKTAIRIPTSNPQTSNNCKNFLTEVLLCXALAPVYFLL 1109
RKYIPK AIRIPTSNPQTSNNCKN LTE+LL ALAP+YFLL
Sbjct: 961 RKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL 1002
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 1926 bits (4990), Expect = 0.0
Identities = 1004/1147 (87%), Positives = 1045/1147 (91%), Gaps = 46/1147 (4%)
Query: 1 MSPWLRPSQAVYPAAAAPGQEPTPQSHPRWLRRAPVSGPDLSSEEERVGSQGQAGPQAGR 60
MSPWLRPSQAV PAAAAPGQEPT P P SGPDLSSE+ R GS GQAG R
Sbjct: 1 MSPWLRPSQAVCPAAAAPGQEPTLSPIPA---DGPWSGPDLSSEK-RGGSHGQAG----R 52
Query: 61 DALLGFRDVPREPRRTRKPATRAPVLQVPPAGHEGLGAASGVPA---------------- 104
DA L FR+VPR+PRRTRKPA P LQ P AGH A SGV A
Sbjct: 53 DARLRFRNVPRQPRRTRKPAAPEPELQSPSAGHASSRAPSGVRAGAELGRRLRVSLLKAV 112
Query: 105 -------------VATMRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIK 151
VATMRKL SFGRRLGQALLSSMDQEYAG GY IRDWELRKIHRAAIK
Sbjct: 113 VDRAGSRILSYIAVATMRKLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIK 172
Query: 152 GDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTP 211
GDAAEVE CLTRRFRDLD RDRKDRTVLHLACAHGRVQVVTLLL R+CQI+ICDRLNRTP
Sbjct: 173 GDAAEVEHCLTRRFRDLDVRDRKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTP 232
Query: 212 LMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALN 271
LMKAVH QEEACAI+LL+ GANPNI+DIYGNTALHYAVYN+GTSLAERLLSHHANIEALN
Sbjct: 233 LMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALN 292
Query: 272 KEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNI 331
KEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNI
Sbjct: 293 KEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNI 352
Query: 332 RISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKE 391
ISSQDMFGQTAEDYA C DLRSI+QQILEHKNKMLKNHLRNDNQETAAMKP NLKKRK+
Sbjct: 353 HISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKK 412
Query: 392 R---------AKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIA 442
R AKAEHNLKVASEEKQERL+RSENKQPQDSQSYGKKKD M+GNFMLK+DIA
Sbjct: 413 RKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIA 472
Query: 443 MLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLK 502
MLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNE+MITK VA+YSQQLNDLK
Sbjct: 473 MLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLK 532
Query: 503 AENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDVSRH 562
AENARLNS+LEKEKHNKERLEAEVESLHS+LATAINEYNEI+ERKDLELVLWRADDVSRH
Sbjct: 533 AENARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRH 592
Query: 563 EKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQ 622
E MGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLAL SVQLDL+QAQ
Sbjct: 593 ETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQ 652
Query: 623 HRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVIN 682
HRIKEMKQMHPNGEAKESQSIGKQNS EERIRQ+ELENLLLERQLEDARKEGDNKEIVIN
Sbjct: 653 HRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVIN 712
Query: 683 IHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTF 742
IHRDCLENGKEDLLEERNKELM EYNYLKEKLLQ EKEKAEREVIVREFQEELVDHLK F
Sbjct: 713 IHRDCLENGKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKF 772
Query: 743 SISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRK 802
S+SESPLEGTSHCHINL+ETWTSKKKLFQVEIQPEEKHEEFRK+FELISLLNYTADQIRK
Sbjct: 773 SMSESPLEGTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRK 832
Query: 803 KNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVA 862
KNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKF+DL+A
Sbjct: 833 KNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMA 892
Query: 863 EKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVE 922
EKEAVSS+CVNLAKDNEVLHQELLSM VQEKCEKLEKDKKMLEE+VLNLKTHMEKDMVE
Sbjct: 893 EKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVE 952
Query: 923 LGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVEC 982
LGK+QEYKSELDERA+Q IEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVEC
Sbjct: 953 LGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVEC 1012
Query: 983 KFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFTEKQRMKY 1042
KFSKMKTAYE+VTTELEE+KEAFA A+KAN+SMS+K+ KSDKKIAVISTKLF EK+RM+Y
Sbjct: 1013 KFSKMKTAYEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEY 1072
Query: 1043 FLSTLPTRPEPELPCVENLNSIELNRKYIPKTAIRIPTSNPQTSNNCKNFLTEVLLCXAL 1102
FLSTLP RP+PELPCVENLNSIELNRKYIPK AIRIPTSNPQTSNNCKN LTE+LL AL
Sbjct: 1073 FLSTLPMRPDPELPCVENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWAL 1132
Query: 1103 APVYFLL 1109
AP+YFLL
Sbjct: 1133 APIYFLL 1139
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 527 bits (1357), Expect = e-149
Identities = 335/821 (40%), Positives = 498/821 (60%), Gaps = 88/821 (10%)
Query: 358 QILEHKNKMLKNHL------RNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQ 411
Q LE + + +K++L RND Q + + N + ++ H K E ++
Sbjct: 838 QTLEMELRTVKSNLNQVVQERNDAQRQLS-REQNARMLQDGILTNHLSKQKEIEMAQKKM 896
Query: 412 RSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITE 471
SEN S S+ ++KD + N ML+++IAML+ E+ IKN + KEKK +++K + E
Sbjct: 897 NSEN-----SHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKE 951
Query: 472 INANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHS 531
N + +K+++ NE+ +T+T+++Y+ +L+ L AENA LNS+LE EK +KERLEAEVES HS
Sbjct: 952 KNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHS 1011
Query: 532 SLATAINEYNEI-VERKDLELVLWRA-DDVSR-HEKMGSNISQLTDKNELLTEQVHKARV 588
LA AI++ ++ +++LEL RA D+ SR +KM ++S L D NE+L++Q+ K
Sbjct: 1012 RLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTES 1071
Query: 589 KFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNS 648
K N+L+ + TRDALREKTL L VQ DL Q Q ++KEM+Q + N + K ++ IGKQ S
Sbjct: 1072 KLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQES 1131
Query: 649 LEERIRQQELENLLLERQLEDARKEGDNKE-IVINIHRDC--------LENGKEDLL-EE 698
+EER+ Q + EN+LL +QL+DA + DNKE VINI E+ K+ LL EE
Sbjct: 1132 VEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEE 1191
Query: 699 RNKELMKEYNYLKEKLLQCEKE-------------------------KAEREVIVR---E 730
RNKEL+ E N+LKE+ Q E E +A EV R
Sbjct: 1192 RNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRIN 1251
Query: 731 FQEELVDHLKTFSISESPLEGTSHCHI-------------------NLNETWTSKKKLFQ 771
++E D K + L+ H N T KK++ +
Sbjct: 1252 LEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDK 1311
Query: 772 VE-IQP--------EEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTI 822
+E +Q E++ E+ +KL EL L DQ KKN ELE E TG+K L+MT
Sbjct: 1312 IEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTR 1371
Query: 823 NMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLH 882
LN + N +FS HGDL T Q +MDI KLK K +DL AE E S+C++L N++L
Sbjct: 1372 KKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQ 1431
Query: 883 QELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEI- 941
+ELLSM+ VQ+KCEKL+K+KK LE+EV+NL++H+E++MVELG++++YK E++ERA QEI
Sbjct: 1432 EELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIA 1491
Query: 942 EKLEEIH--LQKQAEYEKQLEQLNKDNTASLKKK-ELTLKDVECKFSKMKTAYEEVT-TE 997
EKL+E++ LQ QA ++ LEQ ++N AS+K + EL +KD+E + SK+KT+ E+ TE
Sbjct: 1492 EKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTE 1551
Query: 998 LEEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFTEKQRMKYFLSTLPTRPEPELPC 1057
LE++K+ + +K S+S KL K+++++A ++TKL EKQ+ + +TL TRP E PC
Sbjct: 1552 LEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPC 1611
Query: 1058 VENL-NSIELNRKYIPKTAIRIPTSNPQTSNN-CKNFLTEV 1096
V NL NS++LNRK IP+ + I TSNP+ SNN +N+L+++
Sbjct: 1612 VGNLNNSLDLNRKLIPRENLVISTSNPRASNNSMENYLSKM 1652
Score = 207 bits (527), Expect = 6e-53
Identities = 99/185 (53%), Positives = 140/185 (75%)
Query: 130 YAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQ 189
Y+ PGY +RD +L KIH+AA G+ A+V++ L R L+ RD+ +RT LHLACA+G +
Sbjct: 35 YSQPGYHVRDRDLGKIHKAASAGNVAKVQQILLLRKNGLNDRDKMNRTALHLACANGHPE 94
Query: 190 VVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAV 249
VVTLL+ R+CQ+++CD NRT LMKAV QEE CA +LLE GA+PN+ D++GNTALHYAV
Sbjct: 95 VVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHGADPNLADVHGNTALHYAV 154
Query: 250 YNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRT 309
YN+ S+A +LL + ANIEA NK+ TPLL A++ ++Q MVEFL+K +AN++AVD + +
Sbjct: 155 YNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESS 214
Query: 310 ALILA 314
+++
Sbjct: 215 HQLIS 219
Score = 70.1 bits (170), Expect = 1e-11
Identities = 150/743 (20%), Positives = 305/743 (41%), Gaps = 94/743 (12%)
Query: 338 MFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRN--DNQETAAMKPANLKKRKERAKA 395
M G A D R++ + ++ HL+ + +++ K +K + A
Sbjct: 463 MSGSRNFKMAKLEDTRNVGMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAA 522
Query: 396 EHNLKVASEEKQERLQRSENKQPQDSQSYGKKK-----------DAMYGNFMLKKDIAML 444
EH+L+VASEE+QER + SEN QPQ + K + D + D L
Sbjct: 523 EHDLEVASEEEQER-EGSENNQPQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGL 581
Query: 445 KEELYAIKNDSL---RKEKK---------YIQEIKSITEINANFEKSVRL----NEKMIT 488
++ + + D RKE K ++E+KS + ++SV ++T
Sbjct: 582 IQKRKSGETDHQQFPRKENKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLT 641
Query: 489 KTVARYSQQ--LNDLKAENARLNSELEKEKHN-KERLEA--EVESLHSSLATAINE---- 539
+ + L+++ + R + EK+ K ++++ +V+ L S TA +
Sbjct: 642 GGLLQVDDDSSLSEIDEDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELP 701
Query: 540 ------YNEIVERKDLELVLWRADDVSRHEKMGSNIS--QLTD--KN--ELLTEQVHKAR 587
+ ++E+ +E D VS + + +S +L + KN ELLT ++ K
Sbjct: 702 HSSYKNFMLLIEQLGMEC----KDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKME 757
Query: 588 VKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQN 647
K N L+ +L ET++ + + +L + + + ++ N + + +
Sbjct: 758 DKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLR 817
Query: 648 SLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKE- 706
EE+ R++ LE L+ E + +N + + L E+N ++++
Sbjct: 818 RKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDG 877
Query: 707 --YNYL-KEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETW 763
N+L K+K ++ ++K E +E+ + H K + E N+
Sbjct: 878 ILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSH-KNSMLQEEIAMLRLEIDTIKNQNQ 936
Query: 764 TSKKKLFQVEIQPEEKHEEFRK--------LFELISLLNYTADQIRKKNRELE---EEAT 812
+KK F+ +EK+E+ +K L + IS N + +N L E
Sbjct: 937 EKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEK 996
Query: 813 GYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECV 872
K+ LE + ++ T + ++++ F++ + + + L ++ ++ +
Sbjct: 997 QSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRL---QDKMNFDVS 1053
Query: 873 NLAKDNEVLHQELLSMRNVQEKCE-KLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKS 931
NL +NE+L Q+L + E + + L E+ L L E+ +L + Q
Sbjct: 1054 NLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGL----ERVQKDLSQTQCQMK 1109
Query: 932 ELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTA----------SLKKKELTLKDVE 981
E++++ E K+ + ++ KQ E++L QL +N KE T+ +++
Sbjct: 1110 EMEQKYQNEQVKVNK-YIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQ 1168
Query: 982 CKF----SKMKTAYEEVTTELEE 1000
+F K++ E+ + LEE
Sbjct: 1169 DQFHAIVQKLQAESEKQSLLLEE 1191
Score = 46.2 bits (108), Expect = 2e-04
Identities = 113/576 (19%), Positives = 226/576 (39%), Gaps = 75/576 (13%)
Query: 246 HYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFL--LKNQANIHAV 303
H NK ++ HA ++ L E L + R + ++ LK + +
Sbjct: 1154 HNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLL-LEERNKELISECNHLKERQYQYEN 1212
Query: 304 DNFKRTALILAVQHNLSSIVTL--LLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILE 361
+ +R ++ +Q L+ + + + ++ ++S+ E L L IR Q+ E
Sbjct: 1213 EKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQE 1272
Query: 362 HKNKML------------KNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQER 409
+++ K L DN + + K +E K N ++ +EK++
Sbjct: 1273 AQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQL 1332
Query: 410 LQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIK---NDSLRKEKKYIQEI 466
+ E KQ + + K N L+++I K L + N+ E + ++
Sbjct: 1333 KKLMELKQSLECNLDQEMKK----NVELEREITGFKNLLKMTRKKLNEYENGEFSFHGDL 1388
Query: 467 KSITEINANFEKSVRLNEKM-----ITKTVARYSQQLNDLKAENARLNSEL--------- 512
K+ + FE +++N+ +T + + L +N L EL
Sbjct: 1389 KT-----SQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQKK 1443
Query: 513 -EKEKHNKERLEAEVESLHSSLAT------AINEYNEIVERKDLELVLWRADDVS----R 561
EK + NK++LE EV +L S + + +Y + +E + + + + +V+
Sbjct: 1444 CEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNLFLQA 1503
Query: 562 HEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALRE--KTLALGSVQLDLR 619
N+ Q + N + + R+K L+ +L + + + + KT QL L
Sbjct: 1504 QAASQENLEQFRENNFASMKSQMELRIK--DLESELSKIKTSQEDFNKTELEKYKQLYLE 1561
Query: 620 QAQHRIKEMKQMHPNGEAKESQSIGKQNS--LEERIRQQELENLLLERQLEDARKEGD-N 676
+ + R ++ K ++ + + N+ L E+ + + L L R + + G+ N
Sbjct: 1562 ELKVRKSLSSKL-----TKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLN 1616
Query: 677 KEIVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELV 736
+ +N EN R E NYL + + EK I RE +E
Sbjct: 1617 NSLDLNRKLIPRENLVISTSNPRASNNSME-NYLSKMQQELEKN------ITRELKEAAA 1669
Query: 737 DHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQV 772
+ L++ SI+ SPL T ++N + W + ++ QV
Sbjct: 1670 E-LESGSIA-SPLGSTDESNLNQDLVWKASREYVQV 1703
Score = 34.3 bits (77), Expect = 0.87
Identities = 37/179 (20%), Positives = 75/179 (41%), Gaps = 15/179 (8%)
Query: 858 NDLVAEKEAVSSECV--NLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLK-T 914
+DL E S +C + + N +L E L M +D + E +L LK
Sbjct: 685 DDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKDSVSLLKIQDAALSCERLLELKKN 744
Query: 915 HMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKE 974
H E V++ K+++ K + +R + E ++++ ++ E+E++L L
Sbjct: 745 HCELLTVKIKKMED-KVNVLQRELSETKEIKSQLEHQKVEWERELCSLR----------- 792
Query: 975 LTLKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKL 1033
+L E K T YE++ +L +E + V+ + L + ++ + + L
Sbjct: 793 FSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNL 851
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo
sapiens]
Length = 823
Score = 369 bits (948), Expect = e-102
Identities = 289/910 (31%), Positives = 439/910 (48%), Gaps = 132/910 (14%)
Query: 110 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 169
KLF FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVERCL RR DLD
Sbjct: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLD 61
Query: 170 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 229
A D++ RT LHLACA G VQVVTLL++R+CQID+CD+ NRTPL++AVH QEEACA++LLE
Sbjct: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
Query: 230 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 289
GANPN++DIYGNTALHYAVY++ TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
Query: 290 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 349
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA+
Sbjct: 182 VEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
Query: 350 SDLRSIRQQILEHKNKMLK-----------------NHLRNDNQETAAMKPANL-KKRKE 391
L I+QQILEHK K+LK + LR D+ + K N+ K+
Sbjct: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
Query: 392 RAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKK----KDAMYGNFMLKKDIAMLKEE 447
K L +S EK R+ + + P K +D + +K++ L+ E
Sbjct: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
Query: 448 LYAIKNDSLRKEKKYIQEIKSITEI----NANFEKSVRLNEKMITKT----VARYSQQLN 499
A+ S +++++ + K ++ N N + ++L+E + T R +QQ
Sbjct: 362 -QALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
Query: 500 DLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDV 559
K + +L KE+H++ L+ E E +++ + E +ERK+
Sbjct: 421 IGKTYPQQFPKKL-KEEHDRCTLKQENEE-KTNVNMLYKKNREELERKE----------- 467
Query: 560 SRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLR 619
+ K QL + L + AR N E + + E + ++ D+
Sbjct: 468 -KQYKKEVEAKQLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCI----LKADIA 522
Query: 620 QAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEI 679
+ I MK + ++ K+N + I+ + N LE K I
Sbjct: 523 ILRQEICTMK----------NDNLEKENKYLKDIKIVKETNAALE------------KYI 560
Query: 680 VINIHRDCLENGKEDLLEERNKELMKEYNYLK-------EKLLQCEKEKAEREVIVREFQ 732
+N E+++ E +E NYLK +LL+ ++ K E + +Q
Sbjct: 561 KLN----------EEMITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQ 610
Query: 733 EELV-------DHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 785
L + +KT + LE T + + + K + E E+ E K
Sbjct: 611 SRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIK 670
Query: 786 LFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLK 845
L T D +RKK+ LE + + T M + N +
Sbjct: 671 FNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAE------------- 717
Query: 846 MDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKML 905
K N+ + V +L ++N L Q+L D
Sbjct: 718 ---------AKVNNSTGKWNCVEERICHLQRENAWLVQQL---------------DDVHQ 753
Query: 906 EEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKD 965
+E+ + T++++ +E GK E ++ + E + L+E Q + E + + + +D
Sbjct: 754 KEDHKEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTEGVVSIKED 813
Query: 966 NTASLKKKEL 975
+K +
Sbjct: 814 KYFQTSRKTI 823
Score = 32.3 bits (72), Expect = 3.3
Identities = 50/238 (21%), Positives = 97/238 (40%), Gaps = 46/238 (19%)
Query: 851 KKLKQKFNDLVAEKEAVSSECVNLA--KDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEE 908
KKLK++ + ++E VN+ K+ E L ++ EK K E + K LE
Sbjct: 431 KKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERK--------EKQYKKEVEAKQLEPT 482
Query: 909 VLNL----KTHMEKDMVELGKLQEYKSELDERAV---------QEIEKLEEIHLQKQAEY 955
V +L KT + +E K +DE + QEI ++ +L+K+ +Y
Sbjct: 483 VQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKY 542
Query: 956 EKQLEQLNKDNTASLK----------------KKELTLKDVE-----CKFSKMKTAYEEV 994
K ++ + + N A K ++EL E + K K + + +
Sbjct: 543 LKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKKRL 602
Query: 995 TTELEEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFTEKQRMKYFLSTLPTRPE 1052
++E ++ A A+ ++ K + + K+A+ T+ + + M +S + E
Sbjct: 603 EADIESYQSRLAAAISKHSESVK--TERNLKLALERTRDVSVQVEMSSAISKVKDENE 658
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
sapiens]
Length = 823
Score = 369 bits (947), Expect = e-101
Identities = 290/904 (32%), Positives = 437/904 (48%), Gaps = 120/904 (13%)
Query: 110 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 169
KLF FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVERCL RR DLD
Sbjct: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLD 61
Query: 170 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 229
A D++ RT LHLACA G VQVVTLL++R+CQID+CD+ NRTPL++AVH QEEACA++LLE
Sbjct: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
Query: 230 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 289
GANPN++DIYGNTALHYAVY++ TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
Query: 290 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 349
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA+
Sbjct: 182 VEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
Query: 350 SDLRSIRQQILEHKNKMLK-----------------NHLRNDNQETAAMKPANL-KKRKE 391
L I+QQILEHK K+LK + LR D+ + K N+ K+
Sbjct: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
Query: 392 RAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKK----KDAMYGNFMLKKDIAMLKEE 447
K L +S EK R+ + + P K +D + +K++ L+ E
Sbjct: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
Query: 448 LYAIKNDSLRKEKKYIQEIKSITEI----NANFEKSVRLNEKMITKT----VARYSQQLN 499
A+ S +++++ + K ++ N N + ++L+E + T R +QQ
Sbjct: 362 -QALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
Query: 500 DLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDV 559
K + +L KE+H++ L+ E E
Sbjct: 421 IGKTYPQQFPKKL-KEEHDRCTLKQENE-------------------------------- 447
Query: 560 SRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLR 619
EK +N++ L KN E+ K K K +L T +L K+ +
Sbjct: 448 ---EK--TNVNMLYKKNREELERKEKQYKKEVEAK-QLEPTVQSLEMKSKTARNTP---N 498
Query: 620 QAQHRIKEMK-QMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKE 678
+ H +EMK M N K +I +Q + E EN L + ++ ++ E
Sbjct: 499 RDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYL-KDIKIVKETNAALE 557
Query: 679 IVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELV-- 736
I ++ + + +E N +L E L +LL+ ++ K E + +Q L
Sbjct: 558 KYIKLNEEMITETAFRYQQELN-DLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAA 616
Query: 737 -----DHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELIS 791
+ +KT + LE T + + + K + E E+ E K L
Sbjct: 617 ISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKD 676
Query: 792 LLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFK 851
T D +RKK+ LE + + T M + N +
Sbjct: 677 KFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAE------------------- 717
Query: 852 KLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLN 911
K N+ + V +L ++N L Q+L D +E+
Sbjct: 718 ---AKVNNSTGKWNCVEERICHLQRENAWLVQQL---------------DDVHQKEDHKE 759
Query: 912 LKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLK 971
+ T++++ +E GK E ++ + E + L+E Q + E + + + +D
Sbjct: 760 IVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTS 819
Query: 972 KKEL 975
+K++
Sbjct: 820 RKKI 823
Score = 32.7 bits (73), Expect = 2.5
Identities = 49/238 (20%), Positives = 100/238 (42%), Gaps = 46/238 (19%)
Query: 851 KKLKQKFNDLVAEKEAVSSECVNLA--KDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEE 908
KKLK++ + ++E VN+ K+ E L ++ EK K E + K LE
Sbjct: 431 KKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERK--------EKQYKKEVEAKQLEPT 482
Query: 909 VLNL----KTHMEKDMVELGKLQEYKSELDERAV---------QEIEKLEEIHLQKQAEY 955
V +L KT + +E K +DE + QEI ++ +L+K+ +Y
Sbjct: 483 VQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKY 542
Query: 956 EKQLEQLNKDNTASLKKKELT--------------LKDVECKFSKM-------KTAYEEV 994
K ++ + + N A K +L L D++ + +++ K + + +
Sbjct: 543 LKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRL 602
Query: 995 TTELEEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFTEKQRMKYFLSTLPTRPE 1052
++E ++ A A+ ++ K + + K+A+ T+ + + M +S + E
Sbjct: 603 EADIESYQSRLAAAISKHSESVK--TERNLKLALERTRDVSVQVEMSSAISKVKDENE 658
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 368 bits (945), Expect = e-101
Identities = 291/904 (32%), Positives = 435/904 (48%), Gaps = 120/904 (13%)
Query: 110 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 169
KLF FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVERCL RR +LD
Sbjct: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELD 61
Query: 170 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 229
A D++ RT LHLACA G VQVVTLL++R+CQID+CD+ NRTPL++AVH QEEACA++LLE
Sbjct: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
Query: 230 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 289
GANPN++DIYGNTALHYAVY++ TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
Query: 290 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 349
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA+
Sbjct: 182 VEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
Query: 350 SDLRSIRQQILEHKNKMLK-----------------NHLRNDNQETAAMKPANL-KKRKE 391
L I+QQILEHK K+LK + LR D+ + K N+ K+
Sbjct: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
Query: 392 RAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKK----KDAMYGNFMLKKDIAMLKEE 447
K L +S EK R+ + + P K +D + +K++ L+ E
Sbjct: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
Query: 448 L---YAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKT----VARYSQQLND 500
A + + R E+ ++ + N N + ++L+E + T R +QQ
Sbjct: 362 QALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKI 421
Query: 501 LKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDVS 560
K + +L KE+H++ L+ E E
Sbjct: 422 GKTYPQQFPKKL-KEEHDRCTLKQENE--------------------------------- 447
Query: 561 RHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKT-LALGSVQLDLR 619
EK +N++ L KN E+ K K K +L T +L K+ A + D
Sbjct: 448 --EK--TNVNMLYKKNREELERKEKQYKKEVEAK-QLEPTVQSLEMKSKTARNTPNWDF- 501
Query: 620 QAQHRIKEMK-QMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKE 678
H +EMK M N K +I +Q + E EN L + ++ ++ E
Sbjct: 502 ---HNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYL-KDIKIVKETNAALE 557
Query: 679 IVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELV-- 736
I ++ + + +E N +L E L +LL+ ++ K E + +Q L
Sbjct: 558 KYIKLNEEMITETAFRYQQELN-DLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAA 616
Query: 737 -----DHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELIS 791
+ +KT + LE T + + + K + E E+ E K L
Sbjct: 617 ISKHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKD 676
Query: 792 LLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFK 851
T D +RKK+ LE + + T M + N +
Sbjct: 677 KFRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAE------------------- 717
Query: 852 KLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLN 911
K N+ + V +L ++N L Q+L D +E+
Sbjct: 718 ---AKVNNSTGKWNCVEERICHLQRENAWLVQQL---------------DDVHQKEDHKE 759
Query: 912 LKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLK 971
+ T++++ +E GK E ++ + E + L+E Q + E + + + +D
Sbjct: 760 IVTNIQRGFIESGKKDFVLEEKSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTS 819
Query: 972 KKEL 975
+K++
Sbjct: 820 RKKI 823
Score = 32.3 bits (72), Expect = 3.3
Identities = 43/203 (21%), Positives = 85/203 (41%), Gaps = 44/203 (21%)
Query: 851 KKLKQKFNDLVAEKEAVSSECVNLA--KDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEE 908
KKLK++ + ++E VN+ K+ E L ++ EK K E + K LE
Sbjct: 431 KKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERK--------EKQYKKEVEAKQLEPT 482
Query: 909 VLNL----KTHMEKDMVELGKLQEYKSELDERAV---------QEIEKLEEIHLQKQAEY 955
V +L KT + +E K +DE + QEI ++ +L+K+ +Y
Sbjct: 483 VQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKY 542
Query: 956 EKQLEQLNKDNTASLKKKELT--------------LKDVECKFSKM-------KTAYEEV 994
K ++ + + N A K +L L D++ + +++ K + + +
Sbjct: 543 LKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRL 602
Query: 995 TTELEEFKEAFAGAVKANNSMSK 1017
++E ++ A A+ ++ K
Sbjct: 603 EADIESYQSRLAAAISKHSESVK 625
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 367 bits (942), Expect = e-101
Identities = 291/905 (32%), Positives = 436/905 (48%), Gaps = 122/905 (13%)
Query: 110 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 169
KLF FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVERCL RR DLD
Sbjct: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLD 61
Query: 170 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 229
A D++ RT LHLAC G VQVVTLL++R+CQID+CD+ NRTPL++AVH QEEACA++LLE
Sbjct: 62 ALDKQHRTALHLACTSGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
Query: 230 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 289
GANPN++DIYGNTALHYAVY++ TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
Query: 290 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 349
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA+
Sbjct: 182 VEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
Query: 350 SDLRSIRQQILEHKNKMLK-----------------NHLRNDNQETAAMKPANL-KKRKE 391
L I+QQILEHK K+LK + LR D+ + K N+ K+
Sbjct: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
Query: 392 RAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKK----KDAMYGNFMLKKDIAMLKEE 447
K L +S EK R+ + + P K +D + +K++ L+ E
Sbjct: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
Query: 448 LYAIKNDSLRKEKKYIQEIKSITEI----NANFEKSVRLNEKMITKT----VARYSQQLN 499
A+ S +++++ + K ++ N N + ++L+E + T R +QQ
Sbjct: 362 -QALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
Query: 500 DLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDV 559
K + +L KE+H++ L+ E E
Sbjct: 421 IGKTYPQQFPKKL-KEEHDRCTLKQENE-------------------------------- 447
Query: 560 SRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKT-LALGSVQLDL 618
EK +N++ L KN E+ K K K +L T +L K+ A + D
Sbjct: 448 ---EK--TNVNMLYKKNREELERKEKQYKKEVEAK-QLEPTVQSLEMKSKTARNTPNWDF 501
Query: 619 RQAQHRIKEMK-QMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNK 677
H +EMK M N K +I +Q + E EN L + ++ ++
Sbjct: 502 ----HNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYL-KDIKIVKETNAAL 556
Query: 678 EIVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELV- 736
E I ++ + + +E N +L E L +LL+ ++ K E + +Q L
Sbjct: 557 EKYIKLNEEMITETAFRYQQELN-DLKAENTRLNAELLKEKESKKRLEADIESYQSRLAA 615
Query: 737 ------DHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELI 790
+ +KT + LE T + + + K + E E+ E K L
Sbjct: 616 AISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKAENEFLTEQLSETQIKFNALK 675
Query: 791 SLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILF 850
T D +RKK+ LE + + T M + N +
Sbjct: 676 DKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAE------------------ 717
Query: 851 KKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVL 910
K N+ + V +L ++N L Q+L D +E+
Sbjct: 718 ----AKVNNSTGKWNCVEERICHLQRENAWLVQQL---------------DDVHQKEDHK 758
Query: 911 NLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASL 970
+ T++++ +E GK E ++ + E + L+E Q + E + + + +D
Sbjct: 759 EIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQT 818
Query: 971 KKKEL 975
+K +
Sbjct: 819 SRKTI 823
Score = 33.1 bits (74), Expect = 1.9
Identities = 49/238 (20%), Positives = 100/238 (42%), Gaps = 46/238 (19%)
Query: 851 KKLKQKFNDLVAEKEAVSSECVNLA--KDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEE 908
KKLK++ + ++E VN+ K+ E L ++ EK K E + K LE
Sbjct: 431 KKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERK--------EKQYKKEVEAKQLEPT 482
Query: 909 VLNL----KTHMEKDMVELGKLQEYKSELDERAV---------QEIEKLEEIHLQKQAEY 955
V +L KT + +E K +DE + QEI ++ +L+K+ +Y
Sbjct: 483 VQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKY 542
Query: 956 EKQLEQLNKDNTASLKKKELT--------------LKDVECKFSKM-------KTAYEEV 994
K ++ + + N A K +L L D++ + +++ K + + +
Sbjct: 543 LKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRL 602
Query: 995 TTELEEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFTEKQRMKYFLSTLPTRPE 1052
++E ++ A A+ ++ K + + K+A+ T+ + + M +S + E
Sbjct: 603 EADIESYQSRLAAAISKHSESVK--TERNLKLALERTRDVSVQVEMSSAISKVKAENE 658
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 353 bits (906), Expect = 6e-97
Identities = 306/936 (32%), Positives = 461/936 (49%), Gaps = 133/936 (14%)
Query: 110 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 169
KLF F R GQ +L S+D Y G GY IR EL+KIH+AA+KGDAAE+ERCL RR DLD
Sbjct: 2 KLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLD 61
Query: 170 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 229
A D++ RT LHLACA G V+VVTLL++R+CQIDI D+ NRTPL++AVH QEEACA++LLE
Sbjct: 62 ALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLE 121
Query: 230 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 289
GANPN++DIYGNTALHYAVY++ TSLAE+LL H NIEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKM 181
Query: 290 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 349
VEFLLKN+A+ HAVD + TAL+LAV ++ IV +LL+Q+I + +QDM G+ AEDYA+
Sbjct: 182 VEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAIS 241
Query: 350 SDLRSIRQQILEHKNKMLKNHLRN--DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ 407
L I+QQILEHK +LKN + + E+A L A + L VA+++
Sbjct: 242 CRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQ-- 299
Query: 408 ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK 467
+ +P S+GK + G K E K+ SL K
Sbjct: 300 --CVPEKVSEPLRGPSHGKGNRIVNG-----------KGEGPPAKHPSL----------K 336
Query: 468 SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE 527
TE+ K A + + L+AE A L E+E+ +ER E +
Sbjct: 337 PSTEMEDPAVKG------------AVQXKNVQTLRAEQA-LPVASEEEQQRRERSEKKQP 383
Query: 528 SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQ-----LTDKNELLT-E 581
+ T +E ++ E AD +++ K+G Q L ++++ T +
Sbjct: 384 QVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK 443
Query: 582 QVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIK-EMKQMHPNGEAKES 640
Q ++ + N L K RE +L+ ++ Q++ + E KQ+ P ++ E
Sbjct: 444 QENEEKTNVNMLHKKNRE---------------ELERKEKQYKKEVEAKQLEPTVQSLEM 488
Query: 641 QSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERN 700
+ +N+ + E +++D E + I I R + K D LE+ N
Sbjct: 489 KPKTARNTPNQDFHNHE--------EVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
Query: 701 K-----ELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHC 755
K ++ KE N EK ++ +E + +Q+EL D LK +
Sbjct: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAF--WYQQELND-LKA---------ENTRL 588
Query: 756 HINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYK 815
+ L + SKKKL + EI+ S + A I K + ++ E K
Sbjct: 589 NSELLKEKESKKKL-EAEIE---------------SYQSRLAAAISKHSENVKTE-RNLK 631
Query: 816 KCLEMTINMLNAF-ANEDFSCHGDLN---TDQL-KMDILFKKLKQKFNDLVAEKEAVSSE 870
LE T ++ + D S D N T+QL KM I F LK KF
Sbjct: 632 LALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFR------------ 679
Query: 871 CVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYK 930
K + L ++ L++ VQ + ++ K ++E + + + K + ++E
Sbjct: 680 -----KTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERI 734
Query: 931 SELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTA 990
+L ++L ++H Q E K++ + +KK+L L++ K K+
Sbjct: 735 CQLQRENPWLEQQLVDVH---QKEDHKEIVINIQRGFIESRKKDLMLEE---KNKKLMNE 788
Query: 991 YEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKI 1026
Y+ + L +++ A V + K S KK+
Sbjct: 789 YDHLKESLFQYERQKAETV-VSIKEDKYFQTSRKKV 823
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 353 bits (906), Expect = 6e-97
Identities = 306/936 (32%), Positives = 461/936 (49%), Gaps = 133/936 (14%)
Query: 110 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 169
KLF F R GQ +L S+D Y G GY IR EL+KIH+AA+KGDAAE+ERCL RR DLD
Sbjct: 2 KLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLD 61
Query: 170 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 229
A D++ RT LHLACA G V+VVTLL++R+CQIDI D+ NRTPL++AVH QEEACA++LLE
Sbjct: 62 ALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLE 121
Query: 230 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 289
GANPN++DIYGNTALHYAVY++ TSLAE+LL H NIEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKM 181
Query: 290 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 349
VEFLLKN+A+ HAVD + TAL+LAV ++ IV +LL+Q+I + +QDM G+ AEDYA+
Sbjct: 182 VEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAIS 241
Query: 350 SDLRSIRQQILEHKNKMLKNHLRN--DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ 407
L I+QQILEHK +LKN + + E+A L A + L VA+++
Sbjct: 242 CRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQ-- 299
Query: 408 ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK 467
+ +P S+GK + G K E K+ SL K
Sbjct: 300 --CVPEKVSEPLRGPSHGKGNRIVNG-----------KGEGPPAKHPSL----------K 336
Query: 468 SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE 527
TE+ K A + + L+AE A L E+E+ +ER E +
Sbjct: 337 PSTEMEDPAVKG------------AVQXKNVQTLRAEQA-LPVASEEEQQRRERSEKKQP 383
Query: 528 SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQ-----LTDKNELLT-E 581
+ T +E ++ E AD +++ K+G Q L ++++ T +
Sbjct: 384 QVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK 443
Query: 582 QVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIK-EMKQMHPNGEAKES 640
Q ++ + N L K RE +L+ ++ Q++ + E KQ+ P ++ E
Sbjct: 444 QENEEKTNVNMLHKKNRE---------------ELERKEKQYKKEVEAKQLEPTVQSLEM 488
Query: 641 QSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERN 700
+ +N+ + E +++D E + I I R + K D LE+ N
Sbjct: 489 KPKTARNTPNQDFHNHE--------EVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
Query: 701 K-----ELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHC 755
K ++ KE N EK ++ +E + +Q+EL D LK +
Sbjct: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAF--WYQQELND-LKA---------ENTRL 588
Query: 756 HINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYK 815
+ L + SKKKL + EI+ S + A I K + ++ E K
Sbjct: 589 NSELLKEKESKKKL-EAEIE---------------SYQSRLAAAISKHSENVKTE-RNLK 631
Query: 816 KCLEMTINMLNAF-ANEDFSCHGDLN---TDQL-KMDILFKKLKQKFNDLVAEKEAVSSE 870
LE T ++ + D S D N T+QL KM I F LK KF
Sbjct: 632 LALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFR------------ 679
Query: 871 CVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYK 930
K + L ++ L++ VQ + ++ K ++E + + + K + ++E
Sbjct: 680 -----KTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERI 734
Query: 931 SELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTA 990
+L ++L ++H Q E K++ + +KK+L L++ K K+
Sbjct: 735 CQLQRENPWLEQQLVDVH---QKEDHKEIVINIQRGFIESRKKDLMLEE---KNKKLMNE 788
Query: 991 YEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKI 1026
Y+ + L +++ A V + K S KK+
Sbjct: 789 YDHLKESLFQYERQKAETV-VSIKEDKYFQTSRKKV 823
>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
Length = 917
Score = 283 bits (724), Expect = 8e-76
Identities = 263/933 (28%), Positives = 442/933 (47%), Gaps = 118/933 (12%)
Query: 130 YAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQ 189
++ PGY +R +L IH+AAI GD +V + R DL+ RD+K+RT L LACAHGR
Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86
Query: 190 VVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAV 249
VV L+ R+CQ+++ D NRT L+KAV QEE CA +LLE GANPN+ D+YGNTALHYA+
Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146
Query: 250 YNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRT 309
N+ S+A +LL++ A+IEA +++G+T LL A+N +++ MV FLLK + ++ A+DNF RT
Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206
Query: 310 ALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKN 369
ALILA ++ +S+V LLQ NI + QD+ G TAEDYA+ S ++IR I E+K +
Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRK 266
Query: 370 HLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKD 429
L+N N +E +L++ SE +QERL+ E+ QPQ + K K
Sbjct: 267 SLQNSN-------------------SEQDLEMTSEGEQERLEGCESSQPQVEE---KMKK 304
Query: 430 AMYGNFMLKKDIAMLKEELYAIKNDSL--RKEKKYIQEIKSITEINANFEKSVR--LNEK 485
+ +++ + Y D L + + + +S + N F++ R NEK
Sbjct: 305 CRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEK 364
Query: 486 MITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVE 545
K+ ++ LND+ + + + + E + E L ++ + +
Sbjct: 365 SKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFML----LIKQSGMECKDFVSLSK 420
Query: 546 RKDLELVLWRADDVS---------RHEKMGSNISQL------TDKNELLTE-QVHKARVK 589
K+ R+ + + +KM +NIS L TDK + +E Q + + K
Sbjct: 421 SKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK 480
Query: 590 FNTLKGKLRETR------DALREKTLALGSVQLDLRQAQHRIKEMKQMHPNG---EAKES 640
L+ L++ + L EK + + + + Q +K+ ++ E K
Sbjct: 481 LCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTV 540
Query: 641 QSIGKQN-SLEERIRQQELENLLLERQLEDARKEGD-----NKEIVINIHRD--CLENGK 692
+S QN ER R EN L+ ++ R E D N+E +D ++
Sbjct: 541 RSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENN 600
Query: 693 EDLLE--ERNKELM--------KEYNYLKEK--LLQCEKEKAEREVIVREFQEE------ 734
EDL + +RN+E + KE N L ++ +L E +K ++ + E + E
Sbjct: 601 EDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRL 660
Query: 735 ---LVDHLKTFSIS---ESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFE 788
L DH + S + + T + +L E S ++ ++ E
Sbjct: 661 AAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSS-----G 715
Query: 789 LISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDI 848
L + L+Y + +++K +E + ++ + + N+ + Q D
Sbjct: 716 LETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDG 775
Query: 849 LFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKC----EKLEKDKKM 904
LF+ L ++ +C + K + + ++ N+Q KC EKL+ + +
Sbjct: 776 LFQ--------LQSQNLLYQQQCNDARKKADNQEKTII---NIQVKCEDTVEKLQAECRK 824
Query: 905 LEEEVLNLKTHMEKDMVELGKLQEYKSELDERAV--QEIEKLEEIHLQKQAEYEKQLE-- 960
LEE N K M++ + + +Y+ E +ER V +++++ + L KQ E LE
Sbjct: 825 LEE---NNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEIS 881
Query: 961 ---QLN-KDNTASLKKKELTLKDVECKFSKMKT 989
++N +D SLKKK ++ C M T
Sbjct: 882 SERRINLEDEAQSLKKKLGQMRSQVCMKLSMST 914
>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
sapiens]
Length = 917
Score = 283 bits (724), Expect = 8e-76
Identities = 263/933 (28%), Positives = 442/933 (47%), Gaps = 118/933 (12%)
Query: 130 YAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQ 189
++ PGY +R +L IH+AAI GD +V + R DL+ RD+K+RT L LACAHGR
Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86
Query: 190 VVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAV 249
VV L+ R+CQ+++ D NRT L+KAV QEE CA +LLE GANPN+ D+YGNTALHYA+
Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146
Query: 250 YNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRT 309
N+ S+A +LL++ A+IEA +++G+T LL A+N +++ MV FLLK + ++ A+DNF RT
Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206
Query: 310 ALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKN 369
ALILA ++ +S+V LLQ NI + QD+ G TAEDYA+ S ++IR I E+K +
Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRK 266
Query: 370 HLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKD 429
L+N N +E +L++ SE +QERL+ E+ QPQ + K K
Sbjct: 267 SLQNSN-------------------SEQDLEMTSEGEQERLEGCESSQPQVEE---KMKK 304
Query: 430 AMYGNFMLKKDIAMLKEELYAIKNDSL--RKEKKYIQEIKSITEINANFEKSVR--LNEK 485
+ +++ + Y D L + + + +S + N F++ R NEK
Sbjct: 305 CRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEK 364
Query: 486 MITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVE 545
K+ ++ LND+ + + + + E + E L ++ + +
Sbjct: 365 SKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFML----LIKQSGMECKDFVSLSK 420
Query: 546 RKDLELVLWRADDVS---------RHEKMGSNISQL------TDKNELLTE-QVHKARVK 589
K+ R+ + + +KM +NIS L TDK + +E Q + + K
Sbjct: 421 SKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK 480
Query: 590 FNTLKGKLRETR------DALREKTLALGSVQLDLRQAQHRIKEMKQMHPNG---EAKES 640
L+ L++ + L EK + + + + Q +K+ ++ E K
Sbjct: 481 LCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTV 540
Query: 641 QSIGKQN-SLEERIRQQELENLLLERQLEDARKEGD-----NKEIVINIHRD--CLENGK 692
+S QN ER R EN L+ ++ R E D N+E +D ++
Sbjct: 541 RSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENN 600
Query: 693 EDLLE--ERNKELM--------KEYNYLKEK--LLQCEKEKAEREVIVREFQEE------ 734
EDL + +RN+E + KE N L ++ +L E +K ++ + E + E
Sbjct: 601 EDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRL 660
Query: 735 ---LVDHLKTFSIS---ESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFE 788
L DH + S + + T + +L E S ++ ++ E
Sbjct: 661 AAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSS-----G 715
Query: 789 LISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDI 848
L + L+Y + +++K +E + ++ + + N+ + Q D
Sbjct: 716 LETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDG 775
Query: 849 LFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKC----EKLEKDKKM 904
LF+ L ++ +C + K + + ++ N+Q KC EKL+ + +
Sbjct: 776 LFQ--------LQSQNLLYQQQCNDARKKADNQEKTII---NIQVKCEDTVEKLQAECRK 824
Query: 905 LEEEVLNLKTHMEKDMVELGKLQEYKSELDERAV--QEIEKLEEIHLQKQAEYEKQLE-- 960
LEE N K M++ + + +Y+ E +ER V +++++ + L KQ E LE
Sbjct: 825 LEE---NNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEIS 881
Query: 961 ---QLN-KDNTASLKKKELTLKDVECKFSKMKT 989
++N +D SLKKK ++ C M T
Sbjct: 882 SERRINLEDEAQSLKKKLGQMRSQVCMKLSMST 914
>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
sapiens]
Length = 917
Score = 282 bits (722), Expect = 1e-75
Identities = 263/933 (28%), Positives = 442/933 (47%), Gaps = 118/933 (12%)
Query: 130 YAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQ 189
++ PGY +R +L IH+AAI GD +V + R DL+ RD+K+RT L LACAHGR
Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86
Query: 190 VVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAV 249
VV L+ R+CQ+++ D NRT L+KAV QEE CA +LLE GANPN+ D+YGNTALHYA+
Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146
Query: 250 YNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRT 309
N+ S+A +LL++ A+IEA +++G+T LL A+N +++ MV FLLK + ++ A+DNF RT
Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVAFLLKKKPDLTAIDNFGRT 206
Query: 310 ALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKN 369
ALILA ++ +S+V LLQ NI + QD+ G TAEDYA+ S ++IR I E+K
Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRCK 266
Query: 370 HLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKD 429
L+N N +E +L++ SE +QERL+ E+ QPQ + K K
Sbjct: 267 SLQNSN-------------------SEQDLEMTSEGEQERLEGCESSQPQVEE---KMKK 304
Query: 430 AMYGNFMLKKDIAMLKEELYAIKNDSL--RKEKKYIQEIKSITEINANFEKSVR--LNEK 485
+ +++ + Y D L + + + +S + N F++ R NEK
Sbjct: 305 CRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEK 364
Query: 486 MITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVE 545
K+ ++ LND+ + + + + E + E +E ++ + +
Sbjct: 365 SKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIE----QSGMECKDFVSLSK 420
Query: 546 RKDLELVLWRADDVS---------RHEKMGSNISQL------TDKNELLTE-QVHKARVK 589
K+ R+ + + +KM +NIS L TDK + +E Q + + K
Sbjct: 421 SKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK 480
Query: 590 FNTLKGKLRETR------DALREKTLALGSVQLDLRQAQHRIKEMKQMHPNG---EAKES 640
L+ L++ + L EK + + + + Q +K+ ++ E K
Sbjct: 481 LCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTV 540
Query: 641 QSIGKQN-SLEERIRQQELENLLLERQLEDARKEGD-----NKEIVINIHRD--CLENGK 692
+S QN ER R EN L+ ++ R E D N+E +D ++
Sbjct: 541 RSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENN 600
Query: 693 EDLLE--ERNKELM--------KEYNYLKEK--LLQCEKEKAEREVIVREFQEE------ 734
EDL + +RN+E + KE N L ++ +L E +K ++ + E + E
Sbjct: 601 EDLEKTLKRNEEALTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRL 660
Query: 735 ---LVDHLKTFSIS---ESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFE 788
L DH + S + + T + +L E S ++ ++ E
Sbjct: 661 AAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSS-----G 715
Query: 789 LISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDI 848
L + L+Y + +++K +E + ++ + + N+ + Q D
Sbjct: 716 LETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDG 775
Query: 849 LFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKC----EKLEKDKKM 904
LF+ L ++ +C + K + + ++ N+Q KC EKL+ + +
Sbjct: 776 LFQ--------LQSQNLLYQQQCNDARKKADNQEKTII---NIQVKCEDTVEKLQAECRK 824
Query: 905 LEEEVLNLKTHMEKDMVELGKLQEYKSELDERAV--QEIEKLEEIHLQKQAEYEKQLE-- 960
LEE N K M++ + + +Y+ E +ER V +++++ + L KQ E LE
Sbjct: 825 LEE---NNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEIS 881
Query: 961 ---QLN-KDNTASLKKKELTLKDVECKFSKMKT 989
++N +D SLKKK ++ C M T
Sbjct: 882 SERRINLEDEAQSLKKKLGQMRSQVCMKLSMST 914
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 271 bits (693), Expect = 3e-72
Identities = 238/869 (27%), Positives = 413/869 (47%), Gaps = 167/869 (19%)
Query: 245 LHYAVYNKGTSLAERLLSHHANIEALNKEGNT----PLLFAINSRRQHMVEFLLKNQANI 300
L ++VY L E+L + + +L + +T L + + + LK N+
Sbjct: 610 LSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENM 669
Query: 301 HAV-----DNFKRTALILAVQH-----NLSSIVTLLLQQNIRISSQDM-FGQTAEDYAL- 348
+V K+T L L +Q L + L Q+N + DM + + +E +
Sbjct: 670 VSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIK 729
Query: 349 ---CSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEE 405
C + +QQ+ + +++K N ++ N +++ E + ++ ++
Sbjct: 730 EEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERN--DAQKQLSEEQDARILQDQ 787
Query: 406 ----KQERLQRSENKQPQD-SQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEK 460
KQ+ L+ + K + S + K+KD + + ML+++IA+L+ E+ IKN + +KEK
Sbjct: 788 ILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEK 847
Query: 461 KYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKE 520
KY ++I+++ E N N +K ++LNE+ +T+T+ +YS QLN+L AEN LNSELE K N+E
Sbjct: 848 KYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQE 907
Query: 521 RLEAEVESLHSSLATAINEYNEIVERKDLELVLWRA--DDVSRHEKMGSNISQLTDKNEL 578
RLE E+ES LA A+ + ++ +DL+L R + V H+KM ++S L KNE+
Sbjct: 908 RLEIEMESYRCRLAAAVRDCDQSQTARDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEI 967
Query: 579 LTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAK 638
L+E++ A K N+L+ +L TRDAL ++L L VQ DL Q Q + KE +QM+ ++K
Sbjct: 968 LSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSK 1027
Query: 639 ESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDL--- 695
+ I KQ S+EER+ Q + EN+LL +QL+DA K+ +++E + +D + ++L
Sbjct: 1028 LKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAE 1087
Query: 696 -------LEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESP 748
L+E+NKELM EYN+LKE++ QCEKEKA R++ + E QE +
Sbjct: 1088 SEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETV------------- 1134
Query: 749 LEGTSHC-HINL-NETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRE 806
S C H++ NE ++ LF ++ + + ++K ++
Sbjct: 1135 ---PSRCLHLDAENEVLQLQQTLFSMK------------------AIQKQCETLQKNKKQ 1173
Query: 807 LEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEA 866
L++E K +E NML E H L ++ + K++++K N+ +
Sbjct: 1174 LKQEVVNLKSYMER--NMLERGKAE---WHKLLIEERAR-----KEIEEKLNEAI----- 1218
Query: 867 VSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVEL-GK 925
+ L K V H++L+ +R E+ ++KT ME + +L +
Sbjct: 1219 -----LTLQKQAAVSHEQLVQLR----------------EDNTTSIKTQMELTIKDLESE 1257
Query: 926 LQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFS 985
+ K+ + E+E+ +E++L++ E +L++ N
Sbjct: 1258 ISRIKTSQADFNKTELERYKELYLEEVKVRESLSNELSRTN------------------- 1298
Query: 986 KMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFTEKQRMKYFLS 1045
EV+T+L KE + R + +
Sbjct: 1299 ---EMIAEVSTQLTVEKE---------------------------------QTRSRSLFT 1322
Query: 1046 TLPTRPEPELPCVENLNSIE-LNRKYIPK 1073
TRP E PCV NLN E LNRK+IP+
Sbjct: 1323 AYATRPVLESPCVGNLNDSEGLNRKHIPR 1351
Score = 59.7 bits (143), Expect = 2e-08
Identities = 120/633 (18%), Positives = 268/633 (42%), Gaps = 73/633 (11%)
Query: 372 RNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAM 431
+N NQ + + N K K + + +L S+ E E +Q D Q +
Sbjct: 452 KNMNQNSDSGSTNNYKSLKPKLENLSSLPPDSDRTSEVYLHEELQQ--DMQKF------- 502
Query: 432 YGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK----SITEINANFEKSVR------ 481
K ++ L+EE A+K + ++ K +E++ + TE++
Sbjct: 503 ------KNEVNTLEEEFLALKKEDVQLHKDVEEEMEKHRSNSTELSGTLTDGTTVGNDDD 556
Query: 482 -LNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLE-AEVESLHSSLATAINE 539
LN+++ K + + + E + +++ E + +E +E+ S L+ ++ E
Sbjct: 557 GLNQQIPRKENGEHDRPADKTSNEKNEVKNQIYPEADFADSMEPSEIASEDCELSHSVYE 616
Query: 540 YNEIVERKDLELVLWRADDVSRHEK---MGSNISQLTDKN-ELLTEQVHKARVKFNTLKG 595
N ++ + L + + + R + + ++ +L + + + LT ++ + + L+
Sbjct: 617 -NFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQN 675
Query: 596 KLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQ 655
+L ET+ + L + +L + +K+ N E + + + ++S + RI++
Sbjct: 676 ELSETKKTKLQLELQKIEWEKELYDLRLALKQ-----ENEEKRNADMLYNKDSEQLRIKE 730
Query: 656 QELENLL---------LERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKE 706
+E ++ L R +++ R +N ++V+ D ++ L EE++ ++++
Sbjct: 731 EECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERND----AQKQLSEEQDARILQD 786
Query: 707 YNYL-KEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTS 765
K+K L+ ++K E+ R +E+ + H E L I N+
Sbjct: 787 QILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIK-NQNKQK 845
Query: 766 KKKLFQVEIQPEEKHEEFRKLFEL------ISLLNYTA--DQIRKKNRELEEEATGYKKC 817
+KK F+ +EK++ +K+ +L ++L Y+ + + +N+ L E K+
Sbjct: 846 EKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQN 905
Query: 818 LE-MTINMLN---AFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVN 873
E + I M + A C LK+D F++ +Q++ V + + +
Sbjct: 906 QERLEIEMESYRCRLAAAVRDCDQSQTARDLKLD--FQRTRQEW---VRLHDKMKVDMSG 960
Query: 874 LAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSEL 933
L NE+L ++L N + K L+ + + +E+ +L + Q K E
Sbjct: 961 LQAKNEILSEKL---SNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKET 1017
Query: 934 DERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDN 966
++ E KL++ ++ KQ E++L QL +N
Sbjct: 1018 EQMYQIEQSKLKK-YIAKQESVEERLSQLQSEN 1049
Score = 38.9 bits (89), Expect = 0.035
Identities = 18/36 (50%), Positives = 26/36 (72%)
Query: 384 ANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQ 419
+ L + KE +AE + ++ SEE+QERL+ ENKQPQ
Sbjct: 211 SQLPENKESKEAEQDSELTSEEEQERLKGCENKQPQ 246
Score = 34.7 bits (78), Expect = 0.67
Identities = 18/42 (42%), Positives = 24/42 (57%)
Query: 133 PGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRK 174
P +D+R +L ++HRAA GD VE L +D RDRK
Sbjct: 72 PQHDVRLEDLGELHRAARSGDVPGVEHILAPGDTGVDKRDRK 113
>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]
Length = 561
Score = 253 bits (645), Expect = 1e-66
Identities = 203/592 (34%), Positives = 292/592 (49%), Gaps = 169/592 (28%)
Query: 377 ETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFM 436
E A+K A +K + +AE L VA EE+QER +RSE KQ Q +
Sbjct: 131 EDPAVKGAVQRKNVQTLRAEQTLPVALEEEQERCERSEKKQSQVKEG------------- 177
Query: 437 LKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQ 496
N++ + EK IQ +++ ++ ++ + KT Y Q
Sbjct: 178 ----------------NNTNKSEK--IQLSENVCHSTSSAAADRLTKQRKVGKT---YPQ 216
Query: 497 QLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRA 556
Q +L+KE H++E LE + + +Y + VE K LE +
Sbjct: 217 QFP----------KKLKKE-HDREELERKEK-----------QYKKEVEAKQLEPTVQSL 254
Query: 557 DDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALR---EKTLALGS 613
D +K T + + +LR +K + +
Sbjct: 255 D------------------------------MKLKTTRNTPNQINQSLRYSQKKVIGFRN 284
Query: 614 VQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKE 673
DL Q Q +IKEMK+M+ N EAK + S GK + +EERI Q + EN +E+QL+D ++
Sbjct: 285 SPNDLSQTQQQIKEMKEMYENAEAKVNNSTGKWSCVEERICQLQHENPCIEQQLDDVHQK 344
Query: 674 GDNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQE 733
D+KEIV NI R +E+GK+DL+ ++E N K+ + +C
Sbjct: 345 EDHKEIVTNIQRGFIESGKKDLM-------LEEKN--KKLMNEC---------------- 379
Query: 734 ELVDHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLL 793
DHLK + LFQ E R+ E + ++
Sbjct: 380 ---DHLK--------------------------ESLFQYE----------REKAERVVVV 400
Query: 794 NYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKL 853
R+L++EA K L M + L ++ H +L+ Q+ LF+ +
Sbjct: 401 -----------RQLQQEAADSLKKLTMLESPLEGISHY----HINLDETQVPKKKLFQ-V 444
Query: 854 KQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLK 913
+ +F+D +AEKEAVSS+CVNLAK+ +V QELLSM+ VQ++CEKLE+DKKMLEEE+LNLK
Sbjct: 445 ESQFDDFMAEKEAVSSKCVNLAKEIQVFQQELLSMKKVQQECEKLEEDKKMLEEEILNLK 504
Query: 914 THMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKD 965
THME MVEL KLQEYKSELDERA+Q +EKLEEIHLQ+QAE++KQLEQLNKD
Sbjct: 505 THMENSMVELSKLQEYKSELDERAMQAVEKLEEIHLQEQAEHKKQLEQLNKD 556
>gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo
sapiens]
Length = 498
Score = 248 bits (633), Expect = 3e-65
Identities = 137/292 (46%), Positives = 192/292 (65%), Gaps = 20/292 (6%)
Query: 127 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 186
D + P Y +R +L K+HRAA G+ + + R ++ RD+K RT LHLACA+G
Sbjct: 51 DSAFTEPRYHVRREDLGKLHRAAWWGEVPRADLIVMLRGPGINKRDKKKRTALHLACANG 110
Query: 187 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 246
+VV+LLL R+CQ+ + D RT L+KAV QE+ CA++LL+ G +PN+ D+YGNTALH
Sbjct: 111 NSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALMLLQHGTDPNLPDMYGNTALH 170
Query: 247 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 306
YAVYN+ +A+ LL + A+IE+ NK G TPLL A++ ++Q MV+FL+K +AN++A+D F
Sbjct: 171 YAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQRMVKFLIKKKANLNALDRF 230
Query: 307 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHK-NK 365
RTALILAV+ +SIV+LLLQQNI + SQD+FGQTAEDYA+ S I Q + ++K N+
Sbjct: 231 GRTALILAVRCGSASIVSLLLQQNIDVFSQDVFGQTAEDYAVSSHHSIICQLLSDYKENQ 290
Query: 366 MLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQ 417
M N N N E +LK+ SEE+ +RL+ SEN Q
Sbjct: 291 MPNNSSGNSN-------------------PEQDLKLTSEEEPQRLKGSENSQ 323
>gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo
sapiens]
Length = 544
Score = 243 bits (620), Expect = 9e-64
Identities = 164/490 (33%), Positives = 261/490 (53%), Gaps = 55/490 (11%)
Query: 127 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 186
D + P Y +R +L K+HRAA G + + R D++ RD++ RT LHLA A+G
Sbjct: 88 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANG 147
Query: 187 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 246
+VV LLL RRCQ+++ D RT L+KAV QE+ C ++LLE GA+ NI+D YGNTALH
Sbjct: 148 NSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALH 207
Query: 247 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 306
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 208 YAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRY 267
Query: 307 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 366
RTALILAV +SIV LLL+QN+ +SSQD+ GQTA +YA+ S I + + ++K K
Sbjct: 268 GRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQ 327
Query: 367 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGK 426
+ LK E + E +LK+ SEE+ +RL+ SEN QP+ +
Sbjct: 328 M------------------LKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPE 369
Query: 427 KKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKM 486
+ KD EE + KK+ + E N + ++ +
Sbjct: 370 ----------INKDCDREVEE----------EIKKHGSNPVGLPENLTNGASAGNGDDGL 409
Query: 487 ITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVER 546
I + +R K EN + +E H+ E+ + + + L T I++ +EI+
Sbjct: 410 IPQRKSR--------KPENQQFPDTENEEYHSDEQNDTQ-KQLSEEQNTGISQ-DEILTN 459
Query: 547 KDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLK-------GKLRE 599
K ++ + + S L +N +L E++ K R++ + K K+ E
Sbjct: 460 KQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILE 519
Query: 600 TRDALREKTL 609
++++EK L
Sbjct: 520 EIESVKEKLL 529
>gi|52856430 protein expressed in prostate, ovary, testis, and
placenta 15 [Homo sapiens]
Length = 581
Score = 241 bits (616), Expect = 3e-63
Identities = 163/490 (33%), Positives = 261/490 (53%), Gaps = 55/490 (11%)
Query: 127 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 186
D + P Y +R +L K+HRAA G + + R D++ RD++ RT LHLA A+G
Sbjct: 125 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANG 184
Query: 187 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 246
+VV LLL RRCQ+++ D RT L+KAV QE+ C ++LLE GA+ NI+D YGNTALH
Sbjct: 185 NSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALH 244
Query: 247 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 306
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 307 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 366
RTALILAV +SIV LLL+QN+ +SSQD+ GQTA +YA+ S I + + ++K K
Sbjct: 305 GRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQ 364
Query: 367 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGK 426
+ LK E + E +LK+ SEE+ +RL+ SEN QP+ +
Sbjct: 365 M------------------LKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPE 406
Query: 427 KKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKM 486
+ KD EE + KK+ + E N + ++ +
Sbjct: 407 ----------INKDCDREVEE----------EIKKHGSNPVGLPENLTNGASAGNGDDGL 446
Query: 487 ITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVER 546
I + +R K EN + +E H+ E+ + + + L T I++ +EI+
Sbjct: 447 IPQRKSR--------KPENQQFPDTENEEYHSDEQNDTQ-KQLSEEQNTGISQ-DEILTN 496
Query: 547 KDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLK-------GKLRE 599
K ++ + + S+ L +N +L E++ R++ + K K+ E
Sbjct: 497 KQKQIEVAEKEMNSKLSLSHKKEEDLLRENSMLREEIAMLRLELDETKHQNQLRENKILE 556
Query: 600 TRDALREKTL 609
++++EK L
Sbjct: 557 EIESVKEKLL 566
>gi|209977003 ANKRD26-like family C, member 3 [Homo sapiens]
Length = 545
Score = 241 bits (616), Expect = 3e-63
Identities = 131/294 (44%), Positives = 189/294 (64%), Gaps = 18/294 (6%)
Query: 127 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 186
D + P Y +R +L K+HRAA G + + + D++ +D++ RT LHLA A+G
Sbjct: 162 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANG 221
Query: 187 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 246
+VV LLL RRCQ++I D RT L KAV QE+ CA++LLE G +PNI D YGNTALH
Sbjct: 222 NSEVVKLLLDRRCQLNILDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTALH 281
Query: 247 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 306
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 282 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 341
Query: 307 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 366
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA+ S I Q + ++K K
Sbjct: 342 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSRHNVICQLLSDYKEKQ 401
Query: 367 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQD 420
+ LK E + E +LK+ SEE+ +RL+ SEN QP++
Sbjct: 402 I------------------LKVSSENSNPEQDLKLTSEEESQRLKGSENSQPEE 437
>gi|52856434 POTE ankyrin domain family, member G [Homo sapiens]
Length = 508
Score = 240 bits (613), Expect = 6e-63
Identities = 130/294 (44%), Positives = 189/294 (64%), Gaps = 18/294 (6%)
Query: 127 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 186
D + P Y +R +L K+HRAA G + + + D++ +D++ RT LHLA A+G
Sbjct: 125 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANG 184
Query: 187 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 246
+VV LLL RRCQ++I D RT L KAV +E+ CA++LLE G +PNI D YGNTALH
Sbjct: 185 NSEVVKLLLDRRCQLNILDNKKRTALTKAVQCREDECALMLLEHGTDPNIPDEYGNTALH 244
Query: 247 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 306
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 307 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 366
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA+ S I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHNVICQLLSDYKEKQ 364
Query: 367 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQD 420
+ LK E + E +LK+ SEE+ +RL+ SEN QP++
Sbjct: 365 M------------------LKVSSENSNPEQDLKLTSEEESQRLKGSENSQPEE 400
>gi|239741769 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 [Homo sapiens]
Length = 952
Score = 240 bits (613), Expect = 6e-63
Identities = 161/469 (34%), Positives = 248/469 (52%), Gaps = 51/469 (10%)
Query: 127 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 186
D + P Y +R +L K+HRAA G A + + R D++ +D++ RT LHLA A+G
Sbjct: 125 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 184
Query: 187 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 246
VV LLL RRCQ+++ D RT L KAV QE+ CA++LLE G +PNI D YGNT LH
Sbjct: 185 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 247 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 306
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 307 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 366
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA+ S I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 367 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQD-SQSYG 425
+ LK E + E +LK+ SEE+ +R + SEN QP+ SQ
Sbjct: 365 M------------------LKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPE 406
Query: 426 KKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEK 485
KD G+ +++++ KK+ E N + ++
Sbjct: 407 INKD---GDREVEEEM------------------KKHGSTHVGFPENLTNGATAGNGDDG 445
Query: 486 MITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVE 545
+I +R + EN +S+ + + + E LH + + E+VE
Sbjct: 446 LIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVE 505
Query: 546 RKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLK 594
+ + EL L + EK +N L E++ R++ +T+K
Sbjct: 506 KMNSELSL-----SCKKEK------DFLHENSTLREEIAMLRLELDTMK 543
Score = 77.8 bits (190), Expect = 7e-14
Identities = 82/384 (21%), Positives = 161/384 (41%), Gaps = 43/384 (11%)
Query: 136 DIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLL 195
++ D + R A++ E L D + D T LH A + + LL
Sbjct: 200 NVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALL 259
Query: 196 HRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTS 255
I+ ++ TPL+ VH Q++ L++ AN N D YG TAL AV S
Sbjct: 260 LYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 319
Query: 256 LAERLLSHHANIEALNKEGNTPLLFAINSRR----QHMVEFLLKNQANIHAVDNFKRTAL 311
+ LL + ++ + + G T +A++S Q + ++ K I + ++ L
Sbjct: 320 IVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDL 379
Query: 312 ILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKN------K 365
L + Q ++S + + + R + +++ +H + +
Sbjct: 380 KLTSEEESQRFKGSENSQPEKMSQEPEINKDGD--------REVEEEMKKHGSTHVGFPE 431
Query: 366 MLKNHLRNDNQETAAMKPANLKK---------------------RKERAKAEHNLKVASE 404
L N N + + P + +++ E N + +
Sbjct: 432 NLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHD 491
Query: 405 E----KQERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEK 460
E ++++++ E + S S K+KD ++ N L+++IAML+ EL +K+ S ++K
Sbjct: 492 EILIHEEKQIEVVEKMNSELSLSCKKEKDFLHENSTLREEIAMLRLELDTMKHQSQLRKK 551
Query: 461 KYIQEIKSITEINANFEKSVRLNE 484
KY+++I+S+ + N N K+++LNE
Sbjct: 552 KYLEDIESVKKKNDNLLKALQLNE 575
>gi|224282147 prostate-specific P704P [Homo sapiens]
Length = 508
Score = 240 bits (612), Expect = 8e-63
Identities = 130/294 (44%), Positives = 188/294 (63%), Gaps = 18/294 (6%)
Query: 127 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 186
D + P Y +R +L K+HRAA G + + + D++ +D++ RT LHLA A+G
Sbjct: 125 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANG 184
Query: 187 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 246
+VV LLL RRCQ++I D RT L KAV QE+ CA++LLE G +PNI D YGNTALH
Sbjct: 185 NSEVVKLLLDRRCQLNILDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTALH 244
Query: 247 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 306
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 307 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 366
RT LILAV +SIV+LLL+QNI +SSQD+ GQTA +YA+ S I Q + ++K K
Sbjct: 305 GRTVLILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSRHNVICQLLSDYKEKQ 364
Query: 367 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQD 420
+ LK E + E +LK+ SEE+ +RL+ SEN QP++
Sbjct: 365 I------------------LKVSSENSNPEQDLKLTSEEESQRLKGSENSQPEE 400
>gi|134133226 protein expressed in prostate, ovary, testis, and
placenta 2 [Homo sapiens]
Length = 1075
Score = 239 bits (610), Expect = 1e-62
Identities = 133/304 (43%), Positives = 190/304 (62%), Gaps = 19/304 (6%)
Query: 127 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 186
D + P Y +R +L K+HRAA G + + R D++ +D++ RT LHLA A+G
Sbjct: 125 DSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLASANG 184
Query: 187 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 246
+VV LLL RRCQ+++ D RT L+KAV QE+ CA++LLE G +PNI D YGNT LH
Sbjct: 185 NSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 247 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 306
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 307 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 366
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA+ S I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 367 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQD-SQSYG 425
+ LK E + E LK+ SEE+ +R + SEN QP+ SQ
Sbjct: 365 M------------------LKISSENSNPEQELKLTSEEESQRFKGSENSQPEKMSQELE 406
Query: 426 KKKD 429
KD
Sbjct: 407 INKD 410
Score = 59.3 bits (142), Expect = 3e-08
Identities = 39/128 (30%), Positives = 71/128 (55%), Gaps = 10/128 (7%)
Query: 357 QQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENK 416
QQ + +N+ + +ND Q+ ++ H+ + EEKQ ++ E
Sbjct: 581 QQFPDTENEEYHSDEQNDTQKQFC--------EEQNTGILHDEILIHEEKQ--IEVVEKM 630
Query: 417 QPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF 476
+ S S K+KD ++ N L+++IAML+ EL +K+ S +EKKY+++I+S+ + N N
Sbjct: 631 NSELSLSCKKEKDVLHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKKNDNL 690
Query: 477 EKSVRLNE 484
K+++LNE
Sbjct: 691 LKALQLNE 698
>gi|153791352 prostate, ovary, testis expressed protein on
chromosome 2 [Homo sapiens]
Length = 1075
Score = 239 bits (609), Expect = 2e-62
Identities = 129/293 (44%), Positives = 187/293 (63%), Gaps = 18/293 (6%)
Query: 127 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 186
D + P Y +R +L K+HRAA G + + R D++ +D++ RT LHLA A+G
Sbjct: 125 DSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKQDKQKRTALHLASANG 184
Query: 187 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 246
+VV LLL RRCQ+++ D RT L+KAV QE+ CA++LLE G +PNI D YGNT LH
Sbjct: 185 NSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 247 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 306
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 307 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 366
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA+ S I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 367 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQ 419
+ LK E + E +LK+ SEE+ +R + SEN QP+
Sbjct: 365 M------------------LKISSENSNPEQDLKLTSEEESQRFKGSENSQPE 399
Score = 67.0 bits (162), Expect = 1e-10
Identities = 105/500 (21%), Positives = 186/500 (37%), Gaps = 71/500 (14%)
Query: 144 KIHRAAIKGDAAEVERC---LTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQ 200
K A IK + + C L D + D T LH A + + LL
Sbjct: 205 KKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGAD 264
Query: 201 IDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTSLAERL 260
I+ ++ TPL+ VH Q++ L++ AN N D YG TAL AV S+ L
Sbjct: 265 IESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLL 324
Query: 261 LSHHANIEALNKEGNTPLLFAINSRR----QHMVEFLLKNQANIHAVDNFKRTALILAVQ 316
L + ++ + + G T +A++S Q + ++ K I + ++ L L +
Sbjct: 325 LEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSE 384
Query: 317 HNLSSIVTLLLQQNIRISSQ-------------DMFGQTAEDYALCSDLRS-------IR 356
Q ++S + +M + + L +L +
Sbjct: 385 EESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLTNGVTAGNGDN 444
Query: 357 QQILEHKNKMLKNHLRNDNQETAAMKPANL----------KKRKERAKAEHNLKVASEEK 406
I + K++ +N DN+ + L K E + E +LK+ SEE+
Sbjct: 445 GLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKEKQMPKYSSENSNPEQDLKLTSEEE 504
Query: 407 QERLQRSENKQPQ---DSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYI 463
+RL+ SEN QP+ K D NFM ++ + KK+
Sbjct: 505 SQRLKGSENGQPEKRSQEPEINKDGDRELENFM------------------AIEEMKKHR 546
Query: 464 QEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLE 523
E N + ++ +I +R + EN +S+ + + + E
Sbjct: 547 STHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEE 606
Query: 524 AEVESLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQV 583
LH + + E+VE+ + EL L + EK + +N L E++
Sbjct: 607 QNTGILHDEILIHEEKQIEVVEKMNSELSL-----SCKKEK------DILHENSTLREEI 655
Query: 584 HKARVKFNTLK--GKLRETR 601
R++ +T+K +LRE +
Sbjct: 656 AMLRLELDTMKHQSQLREKK 675
Score = 58.9 bits (141), Expect = 3e-08
Identities = 39/128 (30%), Positives = 71/128 (55%), Gaps = 10/128 (7%)
Query: 357 QQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENK 416
QQ + +N+ + +ND Q+ ++ H+ + EEKQ ++ E
Sbjct: 581 QQFPDTENEEYHSDEQNDTQKQFC--------EEQNTGILHDEILIHEEKQ--IEVVEKM 630
Query: 417 QPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF 476
+ S S K+KD ++ N L+++IAML+ EL +K+ S +EKKY+++I+S+ + N N
Sbjct: 631 NSELSLSCKKEKDILHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKRNDNL 690
Query: 477 EKSVRLNE 484
K+++LNE
Sbjct: 691 LKALQLNE 698
>gi|113413200 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 [Homo sapiens]
Length = 1038
Score = 238 bits (608), Expect = 2e-62
Identities = 130/293 (44%), Positives = 186/293 (63%), Gaps = 18/293 (6%)
Query: 127 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 186
D + P Y +R +L K+HRAA G A + + R D++ +D++ RT LHLA A+G
Sbjct: 88 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 147
Query: 187 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 246
VV LLL RRCQ+++ D RT L KAV QE+ CA++LLE G +PNI D YGNT LH
Sbjct: 148 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 207
Query: 247 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 306
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 208 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 267
Query: 307 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 366
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA+ S I Q + ++K K
Sbjct: 268 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 327
Query: 367 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQ 419
+ LK E + E +LK+ SEE+ +R + SEN QP+
Sbjct: 328 M------------------LKISSENSNPEQDLKLTSEEESQRFKGSENSQPE 362
Score = 62.8 bits (151), Expect = 2e-09
Identities = 100/496 (20%), Positives = 183/496 (36%), Gaps = 66/496 (13%)
Query: 136 DIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLL 195
++ D + R A++ E L D + D T LH A + + LL
Sbjct: 163 NVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALL 222
Query: 196 HRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTS 255
I+ ++ TPL+ VH Q++ L++ AN N D YG TAL AV S
Sbjct: 223 LYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 282
Query: 256 LAERLLSHHANIEALNKEGNTPLLFAINSRR----QHMVEFLLKNQANIHAVDNFKRTAL 311
+ LL + ++ + + G T +A++S Q + ++ K I + ++ L
Sbjct: 283 IVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDL 342
Query: 312 ILAVQHNLSSIVTLLLQQNIRISSQ-------------DMFGQTAEDYALCSDLRSIRQQ 358
L + Q ++S + +M + + L +L +
Sbjct: 343 KLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGVTA 402
Query: 359 -------ILEHKNKMLKNHLRNDNQETAAMKPANL----------KKRKERAKAEHNLKV 401
I + K++ +N DN+ + L K E + E +LK+
Sbjct: 403 GNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDLKL 462
Query: 402 ASEEKQERLQRSENKQPQ---DSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRK 458
SEE+ +RL+ SEN QP+ K D NFM ++ +
Sbjct: 463 TSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFM------------------AIEE 504
Query: 459 EKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHN 518
KK+ E N + ++ +I +R + EN +S+ + +
Sbjct: 505 MKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQK 564
Query: 519 KERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNEL 578
+ E LH + + E+VE+ + EL L + E+ +N +
Sbjct: 565 QFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSL-----SCKKER------DFLHENSM 613
Query: 579 LTEQVHKARVKFNTLK 594
L E++ R++ +T+K
Sbjct: 614 LREEIAMLRLELDTMK 629
Score = 58.2 bits (139), Expect = 6e-08
Identities = 38/128 (29%), Positives = 72/128 (56%), Gaps = 10/128 (7%)
Query: 357 QQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENK 416
QQ + +N+ + +ND Q+ ++ H+ + EEKQ ++ E
Sbjct: 544 QQFPDTENEEYHSDEQNDTQKQFC--------EEQNTGILHDEILIHEEKQ--IEVVEKM 593
Query: 417 QPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF 476
+ S S K++D ++ N ML+++IAML+ EL +K+ S ++KKY+++I+S+ + N N
Sbjct: 594 NSELSLSCKKERDFLHENSMLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKNDNL 653
Query: 477 EKSVRLNE 484
K+++LNE
Sbjct: 654 LKALQLNE 661
>gi|88953571 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 isoform 2 [Homo sapiens]
Length = 1075
Score = 238 bits (608), Expect = 2e-62
Identities = 130/293 (44%), Positives = 186/293 (63%), Gaps = 18/293 (6%)
Query: 127 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 186
D + P Y +R +L K+HRAA G A + + R D++ +D++ RT LHLA A+G
Sbjct: 125 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 184
Query: 187 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 246
VV LLL RRCQ+++ D RT L KAV QE+ CA++LLE G +PNI D YGNT LH
Sbjct: 185 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 247 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 306
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 307 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 366
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA+ S I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 367 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQ 419
+ LK E + E +LK+ SEE+ +R + SEN QP+
Sbjct: 365 M------------------LKISSENSNPEQDLKLTSEEESQRFKGSENSQPE 399
Score = 62.8 bits (151), Expect = 2e-09
Identities = 101/496 (20%), Positives = 182/496 (36%), Gaps = 66/496 (13%)
Query: 136 DIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLL 195
++ D + R A++ E L D + D T LH A + + LL
Sbjct: 200 NVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALL 259
Query: 196 HRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTS 255
I+ ++ TPL+ VH Q++ L++ AN N D YG TAL AV S
Sbjct: 260 LYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 319
Query: 256 LAERLLSHHANIEALNKEGNTPLLFAINSRR----QHMVEFLLKNQANIHAVDNFKRTAL 311
+ LL + ++ + + G T +A++S Q + ++ K I + ++ L
Sbjct: 320 IVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDL 379
Query: 312 ILAVQHNLSSIVTLLLQQNIRISSQ-------------DMFGQTAEDYALCSDLRSIRQQ 358
L + Q ++S + +M + + L +L +
Sbjct: 380 KLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGVTA 439
Query: 359 -------ILEHKNKMLKNHLRNDNQETAAMKPANL----------KKRKERAKAEHNLKV 401
I + K++ +N DN+ + L K E + E +LK+
Sbjct: 440 GNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDLKL 499
Query: 402 ASEEKQERLQRSENKQPQ---DSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRK 458
SEE+ +RL+ SEN QP+ K D NFM ++ +
Sbjct: 500 TSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFM------------------AIEE 541
Query: 459 EKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHN 518
KK+ E N + ++ +I +R + EN +S+ + +
Sbjct: 542 MKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQK 601
Query: 519 KERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNEL 578
+ E LH + + E+VE+ + EL L + EK +N
Sbjct: 602 QFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSL-----SCKKEK------DFLHENST 650
Query: 579 LTEQVHKARVKFNTLK 594
L E++ R++ +T+K
Sbjct: 651 LREEIAMLRLELDTMK 666
Score = 57.0 bits (136), Expect = 1e-07
Identities = 38/128 (29%), Positives = 71/128 (55%), Gaps = 10/128 (7%)
Query: 357 QQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENK 416
QQ + +N+ + +ND Q+ ++ H+ + EEKQ ++ E
Sbjct: 581 QQFPDTENEEYHSDEQNDTQKQFC--------EEQNTGILHDEILIHEEKQ--IEVVEKM 630
Query: 417 QPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF 476
+ S S K+KD ++ N L+++IAML+ EL +K+ S ++KKY+++I+S+ + N N
Sbjct: 631 NSELSLSCKKEKDFLHENSTLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKNDNL 690
Query: 477 EKSVRLNE 484
K+++LNE
Sbjct: 691 LKALQLNE 698
>gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 753
Score = 236 bits (602), Expect = 1e-61
Identities = 166/440 (37%), Positives = 235/440 (53%), Gaps = 35/440 (7%)
Query: 7 PSQAVYPAAAAPG----------------QEPTPQSHPRWLRRAPVSG-PDLSSEEERVG 49
PS + P +A PG + T Q HP W P G P + S +R
Sbjct: 196 PSSRLAPISADPGGDAVAKWGCGPSGGTRRRSTTQPHP-WAAEGPARGTPSVGSLWKRRA 254
Query: 50 SQGQAGPQAGRDALLGFRDVPREPRRTRKPATRAPVLQVPPAGHEGLGAASGVPAVATMR 109
Q GR A L + P P R AT A + A L A A +R
Sbjct: 255 RGRQLNRPWGR-ARLALQGAP--PSRGTSAATAACTGRARAARAVSLPRACWA-GPAKVR 310
Query: 110 KLFSFG----------RRLGQALLSSMDQE-YAGPGYDIRDWELRKIHRAAIKGDAAEVE 158
L + R L+ + + +A P Y I+ + L++IHRA + G+ +++
Sbjct: 311 VLAGYNLQPTIKEDDERERWPTLMERLCSDGFAFPHYYIKPYHLKRIHRAVLHGNLEKLK 370
Query: 159 RCLTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHS 218
L + D + RDRK+RT LHLACA G+ ++V LL+ RRC++++CDR +RTPL+KAV
Sbjct: 371 YLLLTYY-DANKRDRKERTALHLACATGQPEMVHLLVSRRCELNLCDREDRTPLIKAVQL 429
Query: 219 QEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPL 278
++EACA +LL+ GANPNI D +G TALHYAVYN+ TS+ E+LLSH NIE +K PL
Sbjct: 430 RQEACATLLLQNGANPNITDFFGRTALHYAVYNEDTSMIEKLLSHGTNIEECSKCEYQPL 489
Query: 279 LFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDM 338
LFA++ R+ MVEFLLK +AN++A+D R+ALI AV IV LLLQ NI + S+D
Sbjct: 490 LFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQHNIDVLSRDA 549
Query: 339 FGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHN 398
F + A DYA+ + R I I E+K K ++ N N ++ +PA LK + + N
Sbjct: 550 FRKIAGDYAIEAKNRVIFDLIYEYKRKRYEDLPINSNPVSSQKQPA-LKATSGKEDSISN 608
Query: 399 LKVASEEKQERLQRSENKQP 418
+ ++ Q+ S KQP
Sbjct: 609 IATEIKDGQKSGTVSSQKQP 628
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,911,061
Number of Sequences: 37866
Number of extensions: 2683675
Number of successful extensions: 27501
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 535
Number of HSP's successfully gapped in prelim test: 1217
Number of HSP's that attempted gapping in prelim test: 13904
Number of HSP's gapped (non-prelim): 7745
length of query: 1415
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1300
effective length of database: 13,892,928
effective search space: 18060806400
effective search space used: 18060806400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.