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Search of human proteins with 239743047
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239743047 PREDICTED: similar to family with sequence
similarity 157, member B [Homo sapiens]
(384 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239743047 PREDICTED: similar to family with sequence similari... 802 0.0
gi|223646111 family with sequence similarity 157, member B [Homo... 786 0.0
gi|223646109 family with sequence similarity 157, member A [Homo... 765 0.0
gi|239745655 PREDICTED: family with sequence similarity 157, mem... 763 0.0
gi|169169586 PREDICTED: hypothetical protein [Homo sapiens] 43 4e-04
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 39 0.006
gi|110347429 mediator complex subunit 12 [Homo sapiens] 39 0.010
gi|38158015 mastermind-like 3 [Homo sapiens] 38 0.013
gi|55956910 meningioma 1 [Homo sapiens] 38 0.018
gi|187171277 DNA-directed DNA polymerase gamma [Homo sapiens] 37 0.023
gi|4505937 DNA-directed DNA polymerase gamma [Homo sapiens] 37 0.023
gi|90403598 mesoderm posterior 2 homolog [Homo sapiens] 37 0.030
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 37 0.039
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 37 0.039
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 37 0.039
gi|239746282 PREDICTED: hypothetical protein XP_002343723 [Homo ... 37 0.039
gi|120952764 mastermind-like domain containing 1 [Homo sapiens] 37 0.039
gi|40354197 THAP domain containing 11 [Homo sapiens] 36 0.051
gi|56118214 zinc finger protein 161 [Homo sapiens] 36 0.051
gi|239750958 PREDICTED: hypothetical protein XP_002347630 [Homo ... 35 0.087
gi|239745364 PREDICTED: hypothetical protein XP_002343480 [Homo ... 35 0.087
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 35 0.087
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 35 0.087
gi|33286444 mastermind-like 2 [Homo sapiens] 35 0.15
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 35 0.15
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 34 0.19
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 34 0.19
gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens] 34 0.19
gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens] 34 0.19
gi|209862782 hypothetical protein LOC730130 [Homo sapiens] 34 0.19
>gi|239743047 PREDICTED: similar to family with sequence similarity
157, member B [Homo sapiens]
Length = 384
Score = 802 bits (2071), Expect = 0.0
Identities = 384/384 (100%), Positives = 384/384 (100%)
Query: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ
Sbjct: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
Query: 61 KPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRRKTEQHSHPFVKKAF 120
KPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRRKTEQHSHPFVKKAF
Sbjct: 61 KPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRRKTEQHSHPFVKKAF 120
Query: 121 RFSAGPGCGRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFAMKRIWIHRRGEATA 180
RFSAGPGCGRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFAMKRIWIHRRGEATA
Sbjct: 121 RFSAGPGCGRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFAMKRIWIHRRGEATA 180
Query: 181 RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYARGAVIPTGT 240
RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYARGAVIPTGT
Sbjct: 181 RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYARGAVIPTGT 240
Query: 241 PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ 300
PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ
Sbjct: 241 PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ 300
Query: 301 DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVNLVF 360
DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVNLVF
Sbjct: 301 DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVNLVF 360
Query: 361 FIDSPTVIAVPDLQCPTKYSGILY 384
FIDSPTVIAVPDLQCPTKYSGILY
Sbjct: 361 FIDSPTVIAVPDLQCPTKYSGILY 384
>gi|223646111 family with sequence similarity 157, member B [Homo
sapiens]
Length = 384
Score = 786 bits (2030), Expect = 0.0
Identities = 378/384 (98%), Positives = 380/384 (98%)
Query: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ
Sbjct: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
Query: 61 KPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRRKTEQHSHPFVKKAF 120
KPSEDIYKNR+RR+QQQQQQQQQQQLDLLFHQRIQISLWP KQKRRKTEQHSHPFVKKAF
Sbjct: 61 KPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAF 120
Query: 121 RFSAGPGCGRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFAMKRIWIHRRGEATA 180
RFSAGPGC RPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFA KRIWIHRRGEATA
Sbjct: 121 RFSAGPGCRRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFATKRIWIHRRGEATA 180
Query: 181 RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYARGAVIPTGT 240
RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYA GAVIPTGT
Sbjct: 181 RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIPTGT 240
Query: 241 PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ 300
PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ
Sbjct: 241 PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ 300
Query: 301 DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVNLVF 360
DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVNLVF
Sbjct: 301 DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVNLVF 360
Query: 361 FIDSPTVIAVPDLQCPTKYSGILY 384
FIDSPTVIAVPDLQCPTKYSGILY
Sbjct: 361 FIDSPTVIAVPDLQCPTKYSGILY 384
>gi|223646109 family with sequence similarity 157, member A [Homo
sapiens]
Length = 383
Score = 765 bits (1975), Expect = 0.0
Identities = 370/384 (96%), Positives = 375/384 (97%), Gaps = 1/384 (0%)
Query: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ
Sbjct: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
Query: 61 KPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRRKTEQHSHPFVKKAF 120
KPSEDIYKN +++ QQQQQQQQQQQLDLLFHQRIQISLWP KQKRRKTEQHSHPFVKKAF
Sbjct: 61 KPSEDIYKNWQQQ-QQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAF 119
Query: 121 RFSAGPGCGRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFAMKRIWIHRRGEATA 180
RFSAG GCGRPSSNKMLRSMGGGQRP GLGSEFFRLLHDLHLLAFAMKRIWIHRRGEATA
Sbjct: 120 RFSAGSGCGRPSSNKMLRSMGGGQRPTGLGSEFFRLLHDLHLLAFAMKRIWIHRRGEATA 179
Query: 181 RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYARGAVIPTGT 240
RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYA GAVIPTGT
Sbjct: 180 RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIPTGT 239
Query: 241 PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ 300
PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ
Sbjct: 240 PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ 299
Query: 301 DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVNLVF 360
DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPL+CQKQRGAS SSGQH GRVNLVF
Sbjct: 300 DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLRCQKQRGASASSGQHEGRVNLVF 359
Query: 361 FIDSPTVIAVPDLQCPTKYSGILY 384
FI SPTVIAVPDLQCPTKYSG+LY
Sbjct: 360 FIGSPTVIAVPDLQCPTKYSGMLY 383
>gi|239745655 PREDICTED: family with sequence similarity 157, member
C [Homo sapiens]
Length = 387
Score = 763 bits (1970), Expect = 0.0
Identities = 371/387 (95%), Positives = 374/387 (96%), Gaps = 3/387 (0%)
Query: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGN+TMIRHTCPMSVPLSRQVKEVAAQ
Sbjct: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNATMIRHTCPMSVPLSRQVKEVAAQ 60
Query: 61 KPSEDIYKNRRRRRQQQQQQQQQQQ---LDLLFHQRIQISLWPCKQKRRKTEQHSHPFVK 117
KPSEDIYKN RR++QQQQQQQQQQQ LDLLFHQRIQISLWP KQKRRKTEQHSH FVK
Sbjct: 61 KPSEDIYKNWRRQQQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHSFVK 120
Query: 118 KAFRFSAGPGCGRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFAMKRIWIHRRGE 177
KAFRFSA PGCGRPSSNKMLRSMGGGQRP GLGSEFFRLLHDLHLLAF K IWIHRRGE
Sbjct: 121 KAFRFSASPGCGRPSSNKMLRSMGGGQRPTGLGSEFFRLLHDLHLLAFPTKCIWIHRRGE 180
Query: 178 ATARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYARGAVIP 237
ATARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYA GAVIP
Sbjct: 181 ATARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIP 240
Query: 238 TGTPERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGK 297
TGTPERAQPPPPQD LGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGK
Sbjct: 241 TGTPERAQPPPPQDLLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGK 300
Query: 298 VFQDSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVN 357
VFQDSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVN
Sbjct: 301 VFQDSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVN 360
Query: 358 LVFFIDSPTVIAVPDLQCPTKYSGILY 384
LVFFIDSPTVIAVPDLQCPTKYSGILY
Sbjct: 361 LVFFIDSPTVIAVPDLQCPTKYSGILY 387
>gi|169169586 PREDICTED: hypothetical protein [Homo sapiens]
Length = 251
Score = 43.1 bits (100), Expect = 4e-04
Identities = 40/116 (34%), Positives = 47/116 (40%), Gaps = 15/116 (12%)
Query: 178 ATARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYARGAVIP 237
A P A HPA PA +RG A R G T +Q + L RG +
Sbjct: 62 AVPSPPAAAHPARPA--LRGETPAPG----RRGRATTRGEVQPSVRPPLSHRPLRGGGMG 115
Query: 238 TGTPERAQPP------PPQDPLGRRRWLSRNTWGPWPGTT--QPPSPQLLR-NDWG 284
G P + PP PP P GRR WLS GP G + SP + R DWG
Sbjct: 116 RGRPGKGPPPNPSRRLPPAPPGGRRTWLSALATGPAAGGAGRRRRSPPVFRAADWG 171
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 39.3 bits (90), Expect = 0.006
Identities = 32/98 (32%), Positives = 40/98 (40%), Gaps = 10/98 (10%)
Query: 179 TARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYARGAVIPT 238
T RP AP P P V G ++ PGSG+ G A P RL+ + R +P
Sbjct: 565 TKRP-APARPTMPPPQVSGSRSSPPAPPLPPGSGSPGT--PQALPRRLVGSSLRAPTVPP 621
Query: 239 GTPERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSP 276
P PP P RR R+ P P + P SP
Sbjct: 622 -------PLPPTPPQPARRQSRRSPASPSPASPGPASP 652
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 38.5 bits (88), Expect = 0.010
Identities = 24/77 (31%), Positives = 40/77 (51%)
Query: 34 LGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQR 93
L + MI PMS + A P + + +++++QQQQQQQQQQQ +H R
Sbjct: 2021 LQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIR 2080
Query: 94 IQISLWPCKQKRRKTEQ 110
Q +Q++++ +Q
Sbjct: 2081 QQQQQQILRQQQQQQQQ 2097
Score = 32.3 bits (72), Expect = 0.74
Identities = 13/26 (50%), Positives = 21/26 (80%)
Query: 60 QKPSEDIYKNRRRRRQQQQQQQQQQQ 85
Q+ + I + +++++QQQQQQQQQQQ
Sbjct: 2081 QQQQQQILRQQQQQQQQQQQQQQQQQ 2106
Score = 32.3 bits (72), Expect = 0.74
Identities = 13/34 (38%), Positives = 25/34 (73%)
Query: 52 RQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQ 85
+Q +++ Q+ + + +++++QQQQQQQQQQQ
Sbjct: 2082 QQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQ 2115
Score = 30.8 bits (68), Expect = 2.1
Identities = 13/34 (38%), Positives = 24/34 (70%)
Query: 52 RQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQ 85
+Q + Q+ + + + +++++QQQQQQQQQQQ
Sbjct: 2074 QQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQ 2107
Score = 30.8 bits (68), Expect = 2.1
Identities = 14/28 (50%), Positives = 21/28 (75%)
Query: 68 KNRRRRRQQQQQQQQQQQLDLLFHQRIQ 95
+ +++++QQQQQQQQQQQ HQ+ Q
Sbjct: 2093 QQQQQQQQQQQQQQQQQQQQQQQHQQQQ 2120
Score = 30.0 bits (66), Expect = 3.7
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 60 QKPSEDIYKNRRRRRQQQQQQ----QQQQQLDLLFHQRIQISLWPCKQKRRKTEQHSHPF 115
Q+ + + +++++QQQQQQ QQQQQ L Q+ Q +Q++++ +Q
Sbjct: 2056 QQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQ 2115
Query: 116 VKKAFRFSAGPGCGRPSSNKMLRSMG 141
++ + A P +P S + G
Sbjct: 2116 HQQQQQQQAAPPQPQPQSQPQFQRQG 2141
Score = 30.0 bits (66), Expect = 3.7
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 52 RQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQ 85
RQ ++ Q+ + + +++++QQQQ QQQQQQ
Sbjct: 2089 RQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQ 2122
Score = 29.6 bits (65), Expect = 4.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 52 RQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQ 85
RQ ++ + + + +++++QQQQQQQQQQQ
Sbjct: 2080 RQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQ 2113
Score = 29.6 bits (65), Expect = 4.8
Identities = 13/36 (36%), Positives = 24/36 (66%)
Query: 50 LSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQ 85
L +Q ++ Q+ + + +++++QQQ QQQQQQQ
Sbjct: 2088 LRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQ 2123
Score = 29.3 bits (64), Expect = 6.2
Identities = 12/36 (33%), Positives = 25/36 (69%)
Query: 50 LSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQ 85
+ +Q ++ ++ + + +++++QQQQQQQQQQQ
Sbjct: 2079 IRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQ 2114
Score = 28.9 bits (63), Expect = 8.1
Identities = 19/66 (28%), Positives = 36/66 (54%), Gaps = 3/66 (4%)
Query: 52 RQVKEVAAQKPSEDIYKNRRRRRQQ---QQQQQQQQQLDLLFHQRIQISLWPCKQKRRKT 108
+Q ++ Q+ + Y R++++QQ QQQQQQQQQ Q+ Q + ++++
Sbjct: 2062 QQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQ 2121
Query: 109 EQHSHP 114
+Q + P
Sbjct: 2122 QQAAPP 2127
>gi|38158015 mastermind-like 3 [Homo sapiens]
Length = 1133
Score = 38.1 bits (87), Expect = 0.013
Identities = 20/46 (43%), Positives = 31/46 (67%), Gaps = 5/46 (10%)
Query: 45 PMSVPLS-----RQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQ 85
P++VP S Q+K++AAQ+ +++++QQQQQQQQQQQ
Sbjct: 454 PVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQ 499
Score = 30.4 bits (67), Expect = 2.8
Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 5/56 (8%)
Query: 32 LLLGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDI--YKNRRRRRQQQQQQQQQQQ 85
L GN+ + H + LS+++ A + Y +++++QQQQQQQQQQQ
Sbjct: 593 LTYGNTKPLTH---FNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQ 645
Score = 29.6 bits (65), Expect = 4.8
Identities = 20/81 (24%), Positives = 46/81 (56%), Gaps = 6/81 (7%)
Query: 47 SVPLSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRR 106
S P + +K++ + ++ + + ++++ ++Q+QQQQQQ +L Q++Q S P R+
Sbjct: 728 SQPQAAIMKQMLIDQRAQ-LIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLP----RQ 782
Query: 107 KTEQHSHPF-VKKAFRFSAGP 126
+ +P+ V++ +F P
Sbjct: 783 HLQPQRNPYPVQQVNQFQGSP 803
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 37.7 bits (86), Expect = 0.018
Identities = 68/296 (22%), Positives = 107/296 (36%), Gaps = 55/296 (18%)
Query: 23 HVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQ 82
H+ P A L + + + P PL + + + + + +++++QQQQQQQQ
Sbjct: 485 HLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQ 544
Query: 83 QQQLDLLFHQRIQISLWPCKQKRRKTEQHS-----HP-FVKKAFRFSAGP--GCGRPSSN 134
QQQ + + I + ++++ Q + HP V + GP G +P+
Sbjct: 545 QQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFE 604
Query: 135 KMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFAMKRIWI------------HRRG----EA 178
+ S G G+ LG+ + H A + W R G A
Sbjct: 605 REGGSTGAGR----LGTFEQQAPH------LAQESAWFSGPHPPPGDLLPRRMGGSGLPA 654
Query: 179 TARPRAPEHPAPPATAVRG--RDAASQNLKRRPGSG------TDGLRLQGAEPS-RLLRT 229
P P PP G Q R PG G + GL+ G+ L++
Sbjct: 655 DCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQS 714
Query: 230 YARGAVIPTGTPERAQPPP----------PQDPLGRRRWLSRNTWGPWPGTTQPPS 275
G +P+ ER PPP P P G ++T PG PPS
Sbjct: 715 PGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAG--RQSTPHSGPGVNSPPS 768
>gi|187171277 DNA-directed DNA polymerase gamma [Homo sapiens]
Length = 1239
Score = 37.4 bits (85), Expect = 0.023
Identities = 18/37 (48%), Positives = 25/37 (67%)
Query: 49 PLSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQ 85
P+ + V++ P+ D +RRR+QQQQQQQQQQQ
Sbjct: 18 PVPAPGRWVSSSVPASDPSDGQRRRQQQQQQQQQQQQ 54
Score = 32.7 bits (73), Expect = 0.56
Identities = 17/45 (37%), Positives = 26/45 (57%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQLDLL 89
P+ P V A PS+ + +++++QQQQQQQQ QQ +L
Sbjct: 18 PVPAPGRWVSSSVPASDPSDGQRRRQQQQQQQQQQQQQPQQPQVL 62
>gi|4505937 DNA-directed DNA polymerase gamma [Homo sapiens]
Length = 1239
Score = 37.4 bits (85), Expect = 0.023
Identities = 18/37 (48%), Positives = 25/37 (67%)
Query: 49 PLSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQ 85
P+ + V++ P+ D +RRR+QQQQQQQQQQQ
Sbjct: 18 PVPAPGRWVSSSVPASDPSDGQRRRQQQQQQQQQQQQ 54
Score = 32.7 bits (73), Expect = 0.56
Identities = 17/45 (37%), Positives = 26/45 (57%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQLDLL 89
P+ P V A PS+ + +++++QQQQQQQQ QQ +L
Sbjct: 18 PVPAPGRWVSSSVPASDPSDGQRRRQQQQQQQQQQQQQPQQPQVL 62
>gi|90403598 mesoderm posterior 2 homolog [Homo sapiens]
Length = 397
Score = 37.0 bits (84), Expect = 0.030
Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 1/43 (2%)
Query: 244 AQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSC 286
AQ PPPQ LG W+ WG W G SP + GSC
Sbjct: 2 AQSPPPQSLLGHDHWIFAQGWG-WAGHWDSTSPASSSDSSGSC 43
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 36.6 bits (83), Expect = 0.039
Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 7/72 (9%)
Query: 50 LSRQVKEVAAQKPSEDIYKNRRRR-------RQQQQQQQQQQQLDLLFHQRIQISLWPCK 102
L +Q + Q+ ++ YK ++ + +QQQQQQQQQQQ Q+ Q +
Sbjct: 122 LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 181
Query: 103 QKRRKTEQHSHP 114
Q++++ +Q HP
Sbjct: 182 QQQQQQQQQQHP 193
Score = 35.0 bits (79), Expect = 0.11
Identities = 18/55 (32%), Positives = 32/55 (58%)
Query: 56 EVAAQKPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRRKTEQ 110
++ Q+ + + +++++QQQQQQQQQQQ Q+ Q P KQ + + +Q
Sbjct: 149 QLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 203
Score = 31.6 bits (70), Expect = 1.3
Identities = 14/40 (35%), Positives = 27/40 (67%)
Query: 46 MSVPLSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQ 85
+ + L +Q ++ Q+ + + +++++QQQQQQQQQQQ
Sbjct: 146 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 185
Score = 30.0 bits (66), Expect = 3.7
Identities = 16/46 (34%), Positives = 28/46 (60%), Gaps = 3/46 (6%)
Query: 52 RQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQL---DLLFHQRI 94
+Q ++ Q+ + ++ ++QQQQQQQQQQL L+F Q++
Sbjct: 176 QQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 221
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 36.6 bits (83), Expect = 0.039
Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 7/72 (9%)
Query: 50 LSRQVKEVAAQKPSEDIYKNRRRR-------RQQQQQQQQQQQLDLLFHQRIQISLWPCK 102
L +Q + Q+ ++ YK ++ + +QQQQQQQQQQQ Q+ Q +
Sbjct: 30 LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 89
Query: 103 QKRRKTEQHSHP 114
Q++++ +Q HP
Sbjct: 90 QQQQQQQQQQHP 101
Score = 35.0 bits (79), Expect = 0.11
Identities = 18/55 (32%), Positives = 32/55 (58%)
Query: 56 EVAAQKPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRRKTEQ 110
++ Q+ + + +++++QQQQQQQQQQQ Q+ Q P KQ + + +Q
Sbjct: 57 QLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 111
Score = 31.6 bits (70), Expect = 1.3
Identities = 14/40 (35%), Positives = 27/40 (67%)
Query: 46 MSVPLSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQ 85
+ + L +Q ++ Q+ + + +++++QQQQQQQQQQQ
Sbjct: 54 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 93
Score = 30.0 bits (66), Expect = 3.7
Identities = 16/46 (34%), Positives = 28/46 (60%), Gaps = 3/46 (6%)
Query: 52 RQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQL---DLLFHQRI 94
+Q ++ Q+ + ++ ++QQQQQQQQQQL L+F Q++
Sbjct: 84 QQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 129
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 36.6 bits (83), Expect = 0.039
Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 7/72 (9%)
Query: 50 LSRQVKEVAAQKPSEDIYKNRRRR-------RQQQQQQQQQQQLDLLFHQRIQISLWPCK 102
L +Q + Q+ ++ YK ++ + +QQQQQQQQQQQ Q+ Q +
Sbjct: 147 LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 206
Query: 103 QKRRKTEQHSHP 114
Q++++ +Q HP
Sbjct: 207 QQQQQQQQQQHP 218
Score = 35.0 bits (79), Expect = 0.11
Identities = 18/55 (32%), Positives = 32/55 (58%)
Query: 56 EVAAQKPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRRKTEQ 110
++ Q+ + + +++++QQQQQQQQQQQ Q+ Q P KQ + + +Q
Sbjct: 174 QLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 228
Score = 31.6 bits (70), Expect = 1.3
Identities = 14/40 (35%), Positives = 27/40 (67%)
Query: 46 MSVPLSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQ 85
+ + L +Q ++ Q+ + + +++++QQQQQQQQQQQ
Sbjct: 171 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 210
Score = 30.0 bits (66), Expect = 3.7
Identities = 16/46 (34%), Positives = 28/46 (60%), Gaps = 3/46 (6%)
Query: 52 RQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQL---DLLFHQRI 94
+Q ++ Q+ + ++ ++QQQQQQQQQQL L+F Q++
Sbjct: 201 QQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 246
>gi|239746282 PREDICTED: hypothetical protein XP_002343723 [Homo
sapiens]
Length = 725
Score = 36.6 bits (83), Expect = 0.039
Identities = 18/51 (35%), Positives = 22/51 (43%)
Query: 173 HRRGEATARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEP 223
H +G RP P APP G + + NL+R PG G L G P
Sbjct: 523 HGQGVDLTRPSRPRLSAPPDITAFGEEGETDNLRRHPGVGPRSAHLGGLVP 573
Score = 29.3 bits (64), Expect = 6.2
Identities = 31/103 (30%), Positives = 35/103 (33%), Gaps = 25/103 (24%)
Query: 269 GTTQPPSPQLLRNDWGSCGFMVPEA---ARGKVFQDSQ-----------EGAHIRRETVS 314
G P P R WG G + P ARGK SQ R T
Sbjct: 195 GARPRPGPTSSRRPWGRAGGLRPRGKRPARGKKRPSSQRRCSSPSAARASATSAPRPTAP 254
Query: 315 KSVCAEP--WRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGR 355
SV A+P R QR R P C + G + G HG R
Sbjct: 255 SSV-AQPSSARSQRRRAP--------CPHRAGGADGVGSHGAR 288
>gi|120952764 mastermind-like domain containing 1 [Homo sapiens]
Length = 774
Score = 36.6 bits (83), Expect = 0.039
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 24/90 (26%)
Query: 2 GPLFTTIPGAHSGPMRPL-PKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
G L + +P ++ GP P P+K P +Q ++IR P S LS
Sbjct: 441 GHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLIRSLTPTSNLLS--------- 491
Query: 61 KPSEDIYKNRRRRRQQQQQQQQQQQLDLLF 90
QQQQQQQQQQQ +++F
Sbjct: 492 --------------QQQQQQQQQQQANVIF 507
>gi|40354197 THAP domain containing 11 [Homo sapiens]
Length = 314
Score = 36.2 bits (82), Expect = 0.051
Identities = 25/75 (33%), Positives = 39/75 (52%), Gaps = 11/75 (14%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQK 104
P PL + A++P+ RR+++QQQQQQQQQQQ Q+ Q +Q+
Sbjct: 77 PTIFPLRGVNERKVARRPAGAAAARRRQQQQQQQQQQQQQQ-----QQQQQ------QQQ 125
Query: 105 RRKTEQHSHPFVKKA 119
+++ +Q S P A
Sbjct: 126 QQQQQQQSSPSASTA 140
>gi|56118214 zinc finger protein 161 [Homo sapiens]
Length = 521
Score = 36.2 bits (82), Expect = 0.051
Identities = 18/41 (43%), Positives = 27/41 (65%), Gaps = 6/41 (14%)
Query: 63 SEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQ 103
SE+ +++++QQQQQQQQQQQ Q+ ++ WP KQ
Sbjct: 329 SEETSNQKQQQQQQQQQQQQQQQ------QQQHVTSWPGKQ 363
Score = 32.7 bits (73), Expect = 0.56
Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Query: 42 HTCPMSVPLSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPC 101
+TC + + +E + QK + +++++QQQQQQQQQ Q + LW
Sbjct: 317 NTCKQGISKTCMSEETSNQKQQQQ----QQQQQQQQQQQQQQHVTSWPGKQVETLRLWEE 372
Query: 102 KQKRRKTE 109
K RK E
Sbjct: 373 AVKARKKE 380
>gi|239750958 PREDICTED: hypothetical protein XP_002347630 [Homo
sapiens]
Length = 229
Score = 35.4 bits (80), Expect = 0.087
Identities = 26/93 (27%), Positives = 33/93 (35%), Gaps = 10/93 (10%)
Query: 180 ARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAE---PSRLLRTYARGAVI 236
+RP P P P + R S + P + L+L G P+R L R
Sbjct: 55 SRPEGPGPPRPATPSARRPQGLSAGVSAGPAQRSRPLQLAGPRDRAPARALHARTR---- 110
Query: 237 PTGTPERAQPPPPQDPLGRRRWLS--RNTWGPW 267
G R P P + PL R W R W W
Sbjct: 111 -MGRAARGPPAPSRGPLKRVTWTCAVRRLWTSW 142
>gi|239745364 PREDICTED: hypothetical protein XP_002343480 [Homo
sapiens]
Length = 229
Score = 35.4 bits (80), Expect = 0.087
Identities = 26/93 (27%), Positives = 33/93 (35%), Gaps = 10/93 (10%)
Query: 180 ARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAE---PSRLLRTYARGAVI 236
+RP P P P + R S + P + L+L G P+R L R
Sbjct: 55 SRPEGPGPPRPATPSARRPQGLSAGVSAGPAQRSRPLQLAGPRDRAPARALHARTR---- 110
Query: 237 PTGTPERAQPPPPQDPLGRRRWLS--RNTWGPW 267
G R P P + PL R W R W W
Sbjct: 111 -MGRAARGPPAPSRGPLKRVTWTCAVRRLWTSW 142
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 35.4 bits (80), Expect = 0.087
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 17/100 (17%)
Query: 11 AHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNR 70
+HSG PK +PM Q L + Q ++ Q+ + + + +
Sbjct: 3882 SHSGQ----PKLSAQPMGSLQQLQQQQQL-------------QQQQQLQQQQQQQLQQQQ 3924
Query: 71 RRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRRKTEQ 110
+ ++QQ QQQQQQQQL Q++Q +Q++++ +Q
Sbjct: 3925 QLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQ 3964
Score = 35.0 bits (79), Expect = 0.11
Identities = 18/56 (32%), Positives = 37/56 (66%), Gaps = 2/56 (3%)
Query: 52 RQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRRK 107
+Q ++ Q+ + + + +++++QQ QQQQQQQQ+ LL R +S P +Q++++
Sbjct: 3941 QQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLS--PQQQQQQQ 3994
Score = 32.7 bits (73), Expect = 0.56
Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 5/85 (5%)
Query: 10 GAHSGPMRPL-PKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDI-- 66
G H + L K+ A R+ ++ ++ + +Q+ +V Q+
Sbjct: 3533 GVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLM 3592
Query: 67 --YKNRRRRRQQQQQQQQQQQLDLL 89
Y+N+++++QQQQQQQQQQ +L
Sbjct: 3593 AEYRNKQQQQQQQQQQQQQQHSAVL 3617
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 35.4 bits (80), Expect = 0.087
Identities = 18/45 (40%), Positives = 26/45 (57%)
Query: 49 PLSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQR 93
P Q V+ + + +N +++QQQQQQQQQQQL HQ+
Sbjct: 510 PAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQ 554
Score = 28.9 bits (63), Expect = 8.1
Identities = 14/34 (41%), Positives = 21/34 (61%)
Query: 71 RRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQK 104
++++QQQQQQQQQQ L Q++ +QK
Sbjct: 533 QQQQQQQQQQQQQQLATALHQQQLMTQQAALQQK 566
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 34.7 bits (78), Expect = 0.15
Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 6/78 (7%)
Query: 52 RQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQ------LDLLFHQRIQISLWPCKQKR 105
+Q ++AQ+ + + +++++QQQQQQQQQQQ L Q + S P +QK
Sbjct: 631 QQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKL 690
Query: 106 RKTEQHSHPFVKKAFRFS 123
+ + P ++ S
Sbjct: 691 LLQQMQNQPIAGMGYQVS 708
Score = 33.9 bits (76), Expect = 0.25
Identities = 18/66 (27%), Positives = 38/66 (57%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQK 104
P + ++Q ++ Q+ + + +++++QQQQQQQQQQQ + Q+ Q Q+
Sbjct: 581 PSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQ 640
Query: 105 RRKTEQ 110
+++ +Q
Sbjct: 641 QQQQQQ 646
Score = 33.1 bits (74), Expect = 0.43
Identities = 16/59 (27%), Positives = 36/59 (61%)
Query: 52 RQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRRKTEQ 110
+Q ++ Q+ + + +++++QQQQQQQQQ + Q+ Q S+ +Q++++ +Q
Sbjct: 590 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQ 648
Score = 32.3 bits (72), Expect = 0.74
Identities = 15/25 (60%), Positives = 20/25 (80%)
Query: 61 KPSEDIYKNRRRRRQQQQQQQQQQQ 85
KPS Y +++++QQQQQQQQQQQ
Sbjct: 580 KPSLLHYTQQQQQQQQQQQQQQQQQ 604
Score = 31.6 bits (70), Expect = 1.3
Identities = 17/59 (28%), Positives = 35/59 (59%)
Query: 52 RQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRRKTEQ 110
+Q ++ Q+ + + +++++QQQQQQQQQQ Q+ Q S +Q++++ +Q
Sbjct: 589 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQ 647
Score = 31.6 bits (70), Expect = 1.3
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 60 QKPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCK 102
Q+ I +++++QQQQQQQQQQQ Q+ Q S P +
Sbjct: 630 QQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQ 672
Score = 30.4 bits (67), Expect = 2.8
Identities = 15/50 (30%), Positives = 26/50 (52%)
Query: 36 NSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQ 85
NS P +P + + + + + +++++QQQQQQQQQQQ
Sbjct: 563 NSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQ 612
Score = 30.4 bits (67), Expect = 2.8
Identities = 14/34 (41%), Positives = 22/34 (64%)
Query: 52 RQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQ 85
+Q ++AQ+ + +++QQQQQQQQQQQ
Sbjct: 619 QQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQ 652
Score = 30.4 bits (67), Expect = 2.8
Identities = 13/39 (33%), Positives = 26/39 (66%)
Query: 47 SVPLSRQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQ 85
S+ +Q ++ ++ + + +++++QQQQQQQQQQQ
Sbjct: 623 SISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQ 661
Score = 28.9 bits (63), Expect = 8.1
Identities = 19/80 (23%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 36 NSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNRRRRRQQQQ-----QQQQQQQLDLLF 90
N + H +Q ++ Q+ + + +++++QQQQ QQQQQQQ +
Sbjct: 579 NKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISA 638
Query: 91 HQRIQISLWPCKQKRRKTEQ 110
Q+ Q +Q++++ +Q
Sbjct: 639 QQQQQQQQQQQQQQQQQQQQ 658
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 34.7 bits (78), Expect = 0.15
Identities = 30/88 (34%), Positives = 38/88 (43%), Gaps = 18/88 (20%)
Query: 175 RGEATARPRAPEHPAPPATAVRGRDAA----SQNLKRRPGSGTDGLRLQGAEPSRLLRTY 230
R +A ARP AP P PA+ R+A+ SQ+L RR + PS R
Sbjct: 1220 RAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRR----------ESPSPSHQARP- 1268
Query: 231 ARGAVIPTGT-PERAQPPPPQDPLGRRR 257
G P G P RAQP P G ++
Sbjct: 1269 --GVPPPRGVPPARAQPDGTPSPGGSKK 1294
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 34.3 bits (77), Expect = 0.19
Identities = 33/120 (27%), Positives = 43/120 (35%), Gaps = 10/120 (8%)
Query: 188 PAPPATAVRGRDAASQNLKRRPGS-GTDGLRLQGAEPSRLLRTYARGAVIPTGTPERAQP 246
P PP G Q + G+ G G R + P A+G P G P
Sbjct: 668 PGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGT 727
Query: 247 PPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQDSQEGA 306
P+ G GP PG PP Q + + G+ G P+ RG V + EGA
Sbjct: 728 DGPKGASGPA--------GP-PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGA 778
Score = 30.0 bits (66), Expect = 3.7
Identities = 37/124 (29%), Positives = 46/124 (37%), Gaps = 14/124 (11%)
Query: 186 EHPAPPATAVRGRDAASQNLKRRPG----SGTDGLRLQGAEPSRLLRTYARGAVIPTGTP 241
E AP G+D + K PG SG G + +P R GA TG P
Sbjct: 508 ERGAPGNRGFPGQDGLA-GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRP 566
Query: 242 ERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQD 301
A P P G R PG PP PQ R G GF P+ A G+ +
Sbjct: 567 GDAGPQGKVGPSGAPGEDGR------PG---PPGPQGARGQPGVMGFPGPKGANGEPGKA 617
Query: 302 SQEG 305
++G
Sbjct: 618 GEKG 621
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 34.3 bits (77), Expect = 0.19
Identities = 33/120 (27%), Positives = 43/120 (35%), Gaps = 10/120 (8%)
Query: 188 PAPPATAVRGRDAASQNLKRRPGS-GTDGLRLQGAEPSRLLRTYARGAVIPTGTPERAQP 246
P PP G Q + G+ G G R + P A+G P G P
Sbjct: 599 PGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGT 658
Query: 247 PPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQDSQEGA 306
P+ G GP PG PP Q + + G+ G P+ RG V + EGA
Sbjct: 659 DGPKGASGPA--------GP-PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGA 709
Score = 30.0 bits (66), Expect = 3.7
Identities = 37/124 (29%), Positives = 46/124 (37%), Gaps = 14/124 (11%)
Query: 186 EHPAPPATAVRGRDAASQNLKRRPG----SGTDGLRLQGAEPSRLLRTYARGAVIPTGTP 241
E AP G+D + K PG SG G + +P R GA TG P
Sbjct: 439 ERGAPGNRGFPGQDGLA-GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRP 497
Query: 242 ERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQD 301
A P P G R PG PP PQ R G GF P+ A G+ +
Sbjct: 498 GDAGPQGKVGPSGAPGEDGR------PG---PPGPQGARGQPGVMGFPGPKGANGEPGKA 548
Query: 302 SQEG 305
++G
Sbjct: 549 GEKG 552
>gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens]
Length = 1123
Score = 34.3 bits (77), Expect = 0.19
Identities = 16/58 (27%), Positives = 35/58 (60%)
Query: 52 RQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRRKTE 109
+Q +E+ A K +++ +R++ +QQ+Q++QQ+ + L QR++ L + K + E
Sbjct: 119 KQQQEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKE 176
>gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens]
Length = 1122
Score = 34.3 bits (77), Expect = 0.19
Identities = 16/58 (27%), Positives = 35/58 (60%)
Query: 52 RQVKEVAAQKPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRRKTE 109
+Q +E+ A K +++ +R++ +QQ+Q++QQ+ + L QR++ L + K + E
Sbjct: 118 KQQQEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKE 175
>gi|209862782 hypothetical protein LOC730130 [Homo sapiens]
Length = 380
Score = 34.3 bits (77), Expect = 0.19
Identities = 15/19 (78%), Positives = 17/19 (89%)
Query: 67 YKNRRRRRQQQQQQQQQQQ 85
Y +RRR+QQQQQQQQQQQ
Sbjct: 182 YGRQRRRQQQQQQQQQQQQ 200
Score = 31.6 bits (70), Expect = 1.3
Identities = 13/18 (72%), Positives = 17/18 (94%)
Query: 68 KNRRRRRQQQQQQQQQQQ 85
+ RRR++QQQQQQQQQQ+
Sbjct: 184 RQRRRQQQQQQQQQQQQR 201
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,545,394
Number of Sequences: 37866
Number of extensions: 1055109
Number of successful extensions: 9680
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 113
Number of HSP's successfully gapped in prelim test: 215
Number of HSP's that attempted gapping in prelim test: 6703
Number of HSP's gapped (non-prelim): 1779
length of query: 384
length of database: 18,247,518
effective HSP length: 104
effective length of query: 280
effective length of database: 14,309,454
effective search space: 4006647120
effective search space used: 4006647120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.