Guide to the Human Genome
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Search of human proteins with 239742483

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239742483 PREDICTED: ankyrin repeat domain 33B [Homo
sapiens]
         (494 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169167742 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]     1001   0.0  
gi|239742483 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]     1001   0.0  
gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]      924   0.0  
gi|194097375 ankyrin repeat domain 33 isoform 2 [Homo sapiens]        229   4e-60
gi|194097377 ankyrin repeat domain 33 isoform 1 [Homo sapiens]        213   3e-55
gi|239755481 PREDICTED: similar to Putative uncharacterized prot...    96   1e-19
gi|239744358 PREDICTED: hypothetical protein XP_002343105 [Homo ...    96   1e-19
gi|62988328 ankyrin repeat domain 50 [Homo sapiens]                    75   1e-13
gi|24308163 fem-1 homolog a [Homo sapiens]                             71   2e-12
gi|96975023 ankyrin repeat and death domain containing 1A [Homo ...    71   3e-12
gi|46519154 ankyrin repeat and KH domain containing 1 isoform 3 ...    69   1e-11
gi|46519151 ankyrin repeat and KH domain containing 1 isoform 2 ...    69   1e-11
gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 ...    69   1e-11
gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]                     69   1e-11
gi|169208819 PREDICTED: similar to kinase D-interacting substrat...    66   6e-11
gi|169208593 PREDICTED: similar to kinase D-interacting substrat...    66   6e-11
gi|55741641 kinase D-interacting substrate of 220 kDa [Homo sapi...    66   6e-11
gi|70995267 ankyrin repeat domain 29 [Homo sapiens]                    65   1e-10
gi|169208169 PREDICTED: similar to kinase D-interacting substrat...    64   4e-10
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]         63   5e-10
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]         63   5e-10
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]         63   5e-10
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]         63   5e-10
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]         63   5e-10
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]         63   5e-10
gi|110431370 espin [Homo sapiens]                                      62   1e-09
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap...    60   5e-09
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap...    60   5e-09
gi|89363047 death-associated protein kinase 1 [Homo sapiens]           59   1e-08
gi|17864094 feminization 1 homolog a [Homo sapiens]                    58   2e-08

>gi|169167742 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
          Length = 494

 Score = 1001 bits (2588), Expect = 0.0
 Identities = 494/494 (100%), Positives = 494/494 (100%)

Query: 1   MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYP 60
           MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYP
Sbjct: 1   MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYP 60

Query: 61  FEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRN 120
           FEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRN
Sbjct: 61  FEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRN 120

Query: 121 GRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPG 180
           GRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPG
Sbjct: 121 GRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPG 180

Query: 181 LDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV 240
           LDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV
Sbjct: 181 LDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV 240

Query: 241 RLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPE 300
           RLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPE
Sbjct: 241 RLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPE 300

Query: 301 DGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEED 360
           DGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEED
Sbjct: 301 DGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEED 360

Query: 361 EVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPG 420
           EVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPG
Sbjct: 361 EVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPG 420

Query: 421 VVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAE 480
           VVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAE
Sbjct: 421 VVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAE 480

Query: 481 AQKERRTAPWKKRT 494
           AQKERRTAPWKKRT
Sbjct: 481 AQKERRTAPWKKRT 494


>gi|239742483 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
          Length = 494

 Score = 1001 bits (2588), Expect = 0.0
 Identities = 494/494 (100%), Positives = 494/494 (100%)

Query: 1   MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYP 60
           MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYP
Sbjct: 1   MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYP 60

Query: 61  FEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRN 120
           FEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRN
Sbjct: 61  FEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRN 120

Query: 121 GRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPG 180
           GRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPG
Sbjct: 121 GRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPG 180

Query: 181 LDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV 240
           LDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV
Sbjct: 181 LDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV 240

Query: 241 RLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPE 300
           RLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPE
Sbjct: 241 RLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPE 300

Query: 301 DGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEED 360
           DGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEED
Sbjct: 301 DGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEED 360

Query: 361 EVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPG 420
           EVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPG
Sbjct: 361 EVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPG 420

Query: 421 VVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAE 480
           VVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAE
Sbjct: 421 VVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAE 480

Query: 481 AQKERRTAPWKKRT 494
           AQKERRTAPWKKRT
Sbjct: 481 AQKERRTAPWKKRT 494


>gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
          Length = 1006

 Score =  924 bits (2389), Expect = 0.0
 Identities = 466/490 (95%), Positives = 469/490 (95%), Gaps = 3/490 (0%)

Query: 8    GPEGGGARCMTPPP-PSPPRGAQ-VEEDPADYEEFEDF-SSLPDTRSIASDDSFYPFEDE 64
            G    GA+   P   PSPP GAQ VEEDPADYEEFED   S    ++  SDDSFYPFEDE
Sbjct: 517  GRRAAGAQLHDPTTQPSPPTGAQQVEEDPADYEEFEDILESARHPQASHSDDSFYPFEDE 576

Query: 65   EEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTG 124
            EEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTG
Sbjct: 577  EEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTG 636

Query: 125  LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 184
            LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE
Sbjct: 637  LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 696

Query: 185  RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQ 244
            RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQ
Sbjct: 697  RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQ 756

Query: 245  RLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGV 304
            RLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGV
Sbjct: 757  RLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGV 816

Query: 305  LDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGG 364
            LDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGG
Sbjct: 817  LDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGG 876

Query: 365  AGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVP 424
            AGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVP
Sbjct: 877  AGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVP 936

Query: 425  RVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKE 484
            RVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKE
Sbjct: 937  RVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKE 996

Query: 485  RRTAPWKKRT 494
            RRTAPWKKRT
Sbjct: 997  RRTAPWKKRT 1006



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 41/150 (27%), Positives = 56/150 (37%), Gaps = 27/150 (18%)

Query: 327 VCPES-PPSVGKRRLAVQEILAARA---ARGPQAQEEDEVGGAGQRGRTGQEDADSREGS 382
           V PE+  P  G+  L   E          RGP A     + G G+ G+   E    R   
Sbjct: 370 VSPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGRLQGKGREGKAPGEGVSPRPAP 429

Query: 383 PRAGLPPALGSRGPAAPAP-------RKASLLPLQRLRRRS---------VRPGVV---- 422
           PR G PP   SR P   A         ++ L+P+     R+          R G +    
Sbjct: 430 PRLGKPPR--SRPPQGLAQPPETFFFERSRLVPVSAELERAGHGFSGDAEARSGDLGARP 487

Query: 423 VPRVRVSKAPAPTFQPERPARKGST-KDSG 451
             R  +  APAP  Q  + AR G+  +D G
Sbjct: 488 ASRSSLPSAPAPPAQQPQAARHGAAGRDQG 517


>gi|194097375 ankyrin repeat domain 33 isoform 2 [Homo sapiens]
          Length = 452

 Score =  229 bits (584), Expect = 4e-60
 Identities = 161/430 (37%), Positives = 215/430 (50%), Gaps = 51/430 (11%)

Query: 60  PFEDEEEHGVESAE-SVPEGVPESVPETAT-------LLRAACANNVGLLRTLVRRGVSV 111
           P  +EEE  +      + E +P    ET T       L  A   N+   L+ ++  GVS 
Sbjct: 62  PCLEEEELALHRRRLDMSEALPCPGKETPTPGCRLGALYWACVHNDPTQLQAILDGGVSP 121

Query: 112 EEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIIT 171
           EEA + D NGRTGL+VACYHGF   V  L+ CP +DVN QD  G+TAL+ AAQAGH  + 
Sbjct: 122 EEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLV 181

Query: 172 NYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWA 231
           + LLNY+ GLDLERR+  G TALMKAAM+ R           AD+ A DP RG +  EWA
Sbjct: 182 SLLLNYYVGLDLERRDQRGLTALMKAAMRNRC----------ADLTAVDPVRGKTALEWA 231

Query: 232 TYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVL 291
             T   D V  +++LL RP  EQ  + Y+PE P       +          L + + + L
Sbjct: 232 VLTDSFDTVWRIRQLLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATL 291

Query: 292 TPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAA 351
           +      P++GGVLDH+V  TTSL SP V   C T+CP+ PPS+G R  +V E+L     
Sbjct: 292 SLPFAPSPQEGGVLDHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELL----- 346

Query: 352 RGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQR 411
                      G A       Q    S + SP   +P           +P+      LQ 
Sbjct: 347 -----------GTAPPPPLVPQSPPGSPQRSPWVFVP---------YQSPQGILSKCLQW 386

Query: 412 LRRR-SVRPGVVVPRVRVSKAPAPTFQPERPARKGSTKDSGH--LQIPKWRYKEAKEEKR 468
           L+ R S  P   VP++ +SKA + + Q +          SGH  L +P WRY+E + EKR
Sbjct: 387 LQPRDSTSPRPQVPKILLSKASSSSHQCQP-----KPSPSGHQSLALPLWRYQELRIEKR 441

Query: 469 KAEEAEKKRQ 478
           K EE  +  Q
Sbjct: 442 KQEEEARMAQ 451


>gi|194097377 ankyrin repeat domain 33 isoform 1 [Homo sapiens]
          Length = 272

 Score =  213 bits (542), Expect = 3e-55
 Identities = 117/271 (43%), Positives = 156/271 (57%), Gaps = 14/271 (5%)

Query: 126 IVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLER 185
           +VACYHGF   V  L+ CP +DVN QD  G+TAL+ AAQAGH  + + LLNY+ GLDLER
Sbjct: 1   MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60

Query: 186 RNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQR 245
           R+  G TALMKAAM+ R +C+  L++AGAD+ A DP RG +  EWA  T   D V  +++
Sbjct: 61  RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120

Query: 246 LLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGVL 305
           LL RP  EQ  + Y+PE P       +          L + + + L+      P++GGVL
Sbjct: 121 LLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVL 180

Query: 306 DHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARG------------ 353
           DH+V  TTSL SP V   C T+CP+ PPS+G R  +V E+L    A+             
Sbjct: 181 DHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLVPAEAQSFRTPKSGPSSLA 240

Query: 354 -PQAQE-EDEVGGAGQRGRTGQEDADSREGS 382
            P AQ+ E+E GG GQ G    ED   + G+
Sbjct: 241 IPGAQDREEETGGGGQNGTEVGEDGIGQAGN 271


>gi|239755481 PREDICTED: similar to Putative uncharacterized
          protein ENSP00000334305 [Homo sapiens]
          Length = 771

 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 44/61 (72%), Positives = 51/61 (83%)

Query: 17 MTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYPFEDEEEHGVESAESVP 76
          MTPPPPSP  G QV+ED ADY+EF+DFSSLPDT +IA D SFYPF++EEEHGV+  ESV 
Sbjct: 1  MTPPPPSPLLGTQVKEDRADYKEFQDFSSLPDTHNIAWDHSFYPFQEEEEHGVKGVESVL 60

Query: 77 E 77
          E
Sbjct: 61 E 61



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 37/68 (54%), Positives = 41/68 (60%), Gaps = 6/68 (8%)

Query: 211 LAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAA 270
           LAGA VHAR P  G   +    +      VRL QRLLERPC E   +KY+ ELPP  E A
Sbjct: 93  LAGAVVHARAPAVGCRQRSGHLH------VRLKQRLLERPCQEPLGKKYQLELPPLYERA 146

Query: 271 RKPAGSKN 278
           RKP GSKN
Sbjct: 147 RKPEGSKN 154



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 30/46 (65%), Positives = 35/46 (76%), Gaps = 1/46 (2%)

Query: 449 DSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRTAPWKKRT 494
           D+ HL+ PKW YK   EEK +AEEAEKKRQA+ Q E+  APWKKRT
Sbjct: 206 DTRHLRTPKWPYKVVTEEKPEAEEAEKKRQAKVQ-EKHPAPWKKRT 250


>gi|239744358 PREDICTED: hypothetical protein XP_002343105 [Homo
          sapiens]
          Length = 767

 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 44/61 (72%), Positives = 51/61 (83%)

Query: 17 MTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYPFEDEEEHGVESAESVP 76
          MTPPPPSP  G QV+ED ADY+EF+DFSSLPDT +IA D SFYPF++EEEHGV+  ESV 
Sbjct: 1  MTPPPPSPLLGTQVKEDRADYKEFQDFSSLPDTHNIAWDHSFYPFQEEEEHGVKGVESVL 60

Query: 77 E 77
          E
Sbjct: 61 E 61



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 31/46 (67%), Positives = 36/46 (78%), Gaps = 1/46 (2%)

Query: 449 DSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRTAPWKKRT 494
           D+ HL+ PKW YK A EEK +AEEAEKKRQA+ Q E+R  PWKKRT
Sbjct: 202 DTRHLRTPKWPYKVATEEKPEAEEAEKKRQAKVQ-EKRLPPWKKRT 246



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 36/68 (52%), Positives = 41/68 (60%), Gaps = 6/68 (8%)

Query: 211 LAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAA 270
           LAGA +HAR P  G   +    +      VRL QRLLERPC E   +KY+ ELPP  E A
Sbjct: 93  LAGAVIHARAPAVGCRQRSGHLH------VRLKQRLLERPCQEPLGKKYQLELPPLYERA 146

Query: 271 RKPAGSKN 278
           RKP GSKN
Sbjct: 147 RKPEGSKN 154


>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
          Length = 1429

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 56/170 (32%), Positives = 82/170 (48%), Gaps = 9/170 (5%)

Query: 66  EHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGL 125
           +HG E      +G   +    A L   A   +  ++  L+ RG  V+     D++G T L
Sbjct: 698 DHGAEVNHEDVDG--RTALSVAALCVPASKGHASVVSLLIDRGAEVDHC---DKDGMTPL 752

Query: 126 IVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLER 185
           +VA Y G VD V  L E    DV+  D+ G T L+ AA  GHA + N LL  F G  ++ 
Sbjct: 753 LVAAYEGHVDVVDLLLE-GGADVDHTDNNGRTPLLAAASMGHASVVNTLL--FWGAAVDS 809

Query: 186 RNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTG 235
            ++ G T L  A+ QG  + +R L+  G D + RD   G +P   A + G
Sbjct: 810 IDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDD-AGWTPLHMAAFEG 858



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 55/158 (34%), Positives = 79/158 (50%), Gaps = 8/158 (5%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L  AA   +  ++  L+  GV V+ A   D + RT L  A + G  D V+ L +    +V
Sbjct: 615 LRSAAWGGHTEVVSALLYAGVKVDCA---DADSRTALRAAAWGGHEDIVLNLLQ-HGAEV 670

Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGL---DLERRNAFGFTALMKAAMQGRTDC 205
           N  D+EG TALI AA  GH  I  +LL++   +   D++ R A    AL   A +G    
Sbjct: 671 NKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASV 730

Query: 206 IRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
           +  L+  GA+V   D + GM+P   A Y G VD V L+
Sbjct: 731 VSLLIDRGAEVDHCD-KDGMTPLLVAAYEGHVDVVDLL 767



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 45/120 (37%), Positives = 63/120 (52%), Gaps = 6/120 (5%)

Query: 101 LRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALI 160
           +RTL+  G SV +    D NGRT L  A Y G +D VV L      D+  +D+ G+T L 
Sbjct: 528 IRTLLDNGASVNQC---DSNGRTLLANAAYSGSLD-VVNLLVSRGADLEIEDAHGHTPLT 583

Query: 161 TAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 220
            AA+ GH  + N L+    G ++   +  G+TAL  AA  G T+ + AL+ AG  V   D
Sbjct: 584 LAARQGHTKVVNCLIGC--GANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCAD 641



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 48/158 (30%), Positives = 77/158 (48%), Gaps = 7/158 (4%)

Query: 88   TLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVD 147
            TL   A  N + +    +  G +VE +   D  GRT L V+C+ G ++ V  L    H D
Sbjct: 949  TLYILALENQLTMAEYFLENGANVEAS---DAEGRTALHVSCWQGHMEMVQVLIAY-HAD 1004

Query: 148  VNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIR 207
            VN  D+E  +AL +AA  GH  +   L+ +  G  ++     G TAL  AA +G  D ++
Sbjct: 1005 VNAADNEKRSALQSAAWQGHVKVVQLLIEH--GAVVDHTCNQGATALCIAAQEGHIDVVQ 1062

Query: 208  ALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQR 245
             L+  GAD +  D + G +    A   G    ++L+++
Sbjct: 1063 VLLEHGADPNHAD-QFGRTAMRVAAKNGHSQIIKLLEK 1099



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 39/124 (31%), Positives = 59/124 (47%), Gaps = 4/124 (3%)

Query: 120  NGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFP 179
            +GR  L VA   G  D +V L      DVN +D++G   L   A      +  Y L    
Sbjct: 912  DGRNALRVAALEGHRD-IVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLEN-- 968

Query: 180  GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDA 239
            G ++E  +A G TAL  +  QG  + ++ L+   ADV+A D  +  + Q  A + G V  
Sbjct: 969  GANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQS-AAWQGHVKV 1027

Query: 240  VRLM 243
            V+L+
Sbjct: 1028 VQLL 1031



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 44/141 (31%), Positives = 65/141 (46%), Gaps = 9/141 (6%)

Query: 100 LLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTAL 159
           +L+ LV+ G  V    +     RT  IV       D++  L +     VN  DS G T L
Sbjct: 496 VLQLLVKAGAHVNSEDD-----RTSCIVRQALEREDSIRTLLD-NGASVNQCDSNGRTLL 549

Query: 160 ITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 219
             AA +G   + N L++   G DLE  +A G T L  AA QG T  +  L+  GA+++  
Sbjct: 550 ANAAYSGSLDVVNLLVSR--GADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHT 607

Query: 220 DPRRGMSPQEWATYTGRVDAV 240
           D + G +    A + G  + V
Sbjct: 608 D-QDGWTALRSAAWGGHTEVV 627



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 4/91 (4%)

Query: 87   ATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHV 146
            + L  AA   +V +++ L+  G  V+    T   G T L +A   G +D V  L E    
Sbjct: 1014 SALQSAAWQGHVKVVQLLIEHGAVVDH---TCNQGATALCIAAQEGHIDVVQVLLE-HGA 1069

Query: 147  DVNWQDSEGNTALITAAQAGHAIITNYLLNY 177
            D N  D  G TA+  AA+ GH+ I   L  Y
Sbjct: 1070 DPNHADQFGRTAMRVAAKNGHSQIIKLLEKY 1100


>gi|24308163 fem-1 homolog a [Homo sapiens]
          Length = 669

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 60/202 (29%), Positives = 93/202 (46%), Gaps = 15/202 (7%)

Query: 81  ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 140
           E++     L  A+ A ++ ++R+L+RRG SV     T R   T L  AC+ G ++ V  L
Sbjct: 79  ETIEGAPPLWAASAAGHLDVVRSLLRRGASVNR---TTRTNSTPLRAACFDGHLEVVRYL 135

Query: 141 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 200
                 D+   +  G+T L+ +   GH  I  YLL    G  + RR+A G TAL   A  
Sbjct: 136 VGEHQADLEVANRHGHTCLMISCYKGHREIARYLLE--QGAQVNRRSAKGNTALHDCAES 193

Query: 201 GRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQF-WEKY 259
           G  + ++  +L G          GM+P   A+ TG  + V  +  + E+P  EQ    + 
Sbjct: 194 GSLEILQ--LLLGCKARMERDGYGMTPLLAASVTGHTNIVEYL--IQEQPGQEQVAGGEA 249

Query: 260 RPELPPPPEAARKPAGSKNCLQ 281
           +P LP        P+ S+ C Q
Sbjct: 250 QPGLP-----QEDPSTSQGCAQ 266



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 18/101 (17%)

Query: 155 GNTALITAAQAGHAIITNYLLN------------YFPGLDLERRNAFGFTALMKAAMQGR 202
           G T L+ AA+ GH  +  YL++            +F G  +E     G   L  A+  G 
Sbjct: 41  GGTPLLIAARYGHLDVVEYLVDRCGASVEAGGSVHFDGETIE-----GAPPLWAASAAGH 95

Query: 203 TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
            D +R+L+  GA V+ R  R   +P   A + G ++ VR +
Sbjct: 96  LDVVRSLLRRGASVN-RTTRTNSTPLRAACFDGHLEVVRYL 135


>gi|96975023 ankyrin repeat and death domain containing 1A [Homo
           sapiens]
          Length = 522

 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 53/158 (33%), Positives = 77/158 (48%), Gaps = 8/158 (5%)

Query: 88  TLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL--AECPH 145
           TLL  A       +   +   +        D+ GRT    A  HG +D +  L  + C H
Sbjct: 126 TLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDH 185

Query: 146 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDC 205
              N +D EGNTAL  AA  GH  +   L++   GLDLE +NA G TAL  AA     DC
Sbjct: 186 ---NVKDKEGNTALHLAAGRGHMAVLQRLVDI--GLDLEEQNAEGLTALHSAAGGSHPDC 240

Query: 206 IRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
           ++ L+ AG+ V+A   ++ +S   +A  +G  D  R++
Sbjct: 241 VQLLLRAGSTVNAL-TQKNLSCLHYAALSGSEDVSRVL 277



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 30/128 (23%), Positives = 61/128 (47%), Gaps = 5/128 (3%)

Query: 121 GRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPG 180
           G   L+++ + G +  +  L       ++ +  +G T L  AAQ GH  +  +++     
Sbjct: 91  GMNALLLSAWFGHLRILQILVNSG-AKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLED 149

Query: 181 LDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV 240
           + L+  +  G TA  +AA  G+ D +  L+ +G D + +D + G +    A   G    +
Sbjct: 150 VALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKD-KEGNTALHLAAGRGH---M 205

Query: 241 RLMQRLLE 248
            ++QRL++
Sbjct: 206 AVLQRLVD 213



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 9/111 (8%)

Query: 146 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLD--------LERRNAFGFTALMKA 197
           V+   ++  G  AL  AA AGH      LL +   +D         E R  FG  AL+ +
Sbjct: 39  VNTRARNHVGRVALHWAAGAGHEQAVRLLLEHEAAVDEEDAVGALTEARLCFGMNALLLS 98

Query: 198 AMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLE 248
           A  G    ++ L+ +GA +H  + + G++    A   G V  +  +   LE
Sbjct: 99  AWFGHLRILQILVNSGAKIHC-ESKDGLTLLHCAAQKGHVPVLAFIMEDLE 148



 Score = 32.7 bits (73), Expect = 0.78
 Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)

Query: 96  NNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEG 155
           N   L+R L+    S  +    D   +T L +A  H + D +  +     VD+N +D +G
Sbjct: 302 NFPALVRLLIN---SDSDVNAVDNRQQTPLHLAAEHAWQD-IADMLLIAGVDLNLRDKQG 357

Query: 156 NTALITAAQAGHAIITNYLL 175
            TAL  A ++ H  + + ++
Sbjct: 358 KTALAVAVRSNHVSLVDMII 377


>gi|46519154 ankyrin repeat and KH domain containing 1 isoform 3
           [Homo sapiens]
          Length = 627

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 63/197 (31%), Positives = 87/197 (44%), Gaps = 11/197 (5%)

Query: 48  DTRSIASDDSFYPFEDEEEHGVESAESVPEGVPESVPETATLLRAAC-ANNVGLLRTLVR 106
           DTRS+A   S     D + + V         V E   E  +LL  AC A    L + L+ 
Sbjct: 205 DTRSLAEACS-----DGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 259

Query: 107 RGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAG 166
              +VE+    ++   T L+ A   G++D +V L      DVN Q + GNTAL  A   G
Sbjct: 260 MHANVED--RGNKGDITPLMAASSGGYLD-IVKLLLLHDADVNSQSATGNTALTYACAGG 316

Query: 167 HAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMS 226
              I   LLN   G ++E  N  G T LM+AA  G  +  R L+  GA ++        S
Sbjct: 317 FVDIVKVLLN--EGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKES 374

Query: 227 PQEWATYTGRVDAVRLM 243
               A Y G +D VR +
Sbjct: 375 ALTLACYKGHLDMVRFL 391



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 6/155 (3%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L+ A+    + +++ L+     V     T   G T L  AC  GFVD V  L      ++
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSAT---GNTALTYACAGGFVDIVKVLLN-EGANI 331

Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
              +  G+T L+ AA AGH  +   LL++  G++    N F  +AL  A  +G  D +R 
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHS-NEFKESALTLACYKGHLDMVRF 390

Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
           L+ AGAD   +      +  E A   G V+  RL+
Sbjct: 391 LLEAGADQEHKTDEMHTALME-ACMDGHVEVARLL 424



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 42/131 (32%), Positives = 68/131 (51%), Gaps = 10/131 (7%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L  AAC  +V L   L+ RG ++EE  +    G T L+ A   G  + +VAL      ++
Sbjct: 442 LTLAACGGHVELAALLIERGANLEEVND---EGYTPLMEAAREGH-EEMVALLLAQGANI 497

Query: 149 NWQDSEGN-TALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIR 207
           N Q  E   TAL  A   G + + ++L+    G D+E   +   T LM+A+ +G  + ++
Sbjct: 498 NAQTEETQETALTLACCGGFSEVADFLIK--AGADIELGCS---TPLMEASQEGHLELVK 552

Query: 208 ALMLAGADVHA 218
            L+ +GA+VHA
Sbjct: 553 YLLASGANVHA 563



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 34/162 (20%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L+ AA A +V + R L+  G  +     ++    + L +ACY G +D V  L E    D 
Sbjct: 342 LMEAASAGHVEVARVLLDHGAGINT--HSNEFKESALTLACYKGHLDMVRFLLEAG-ADQ 398

Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFP----------------------------- 179
             +  E +TAL+ A   GH  +   LL+                                
Sbjct: 399 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLI 458

Query: 180 --GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 219
             G +LE  N  G+T LM+AA +G  + +  L+  GA+++A+
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500


>gi|46519151 ankyrin repeat and KH domain containing 1 isoform 2
           [Homo sapiens]
          Length = 616

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 63/197 (31%), Positives = 87/197 (44%), Gaps = 11/197 (5%)

Query: 48  DTRSIASDDSFYPFEDEEEHGVESAESVPEGVPESVPETATLLRAAC-ANNVGLLRTLVR 106
           DTRS+A   S     D + + V         V E   E  +LL  AC A    L + L+ 
Sbjct: 194 DTRSLAEACS-----DGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 248

Query: 107 RGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAG 166
              +VE+    ++   T L+ A   G++D +V L      DVN Q + GNTAL  A   G
Sbjct: 249 MHANVED--RGNKGDITPLMAASSGGYLD-IVKLLLLHDADVNSQSATGNTALTYACAGG 305

Query: 167 HAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMS 226
              I   LLN   G ++E  N  G T LM+AA  G  +  R L+  GA ++        S
Sbjct: 306 FVDIVKVLLN--EGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKES 363

Query: 227 PQEWATYTGRVDAVRLM 243
               A Y G +D VR +
Sbjct: 364 ALTLACYKGHLDMVRFL 380



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 6/155 (3%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L+ A+    + +++ L+     V     T   G T L  AC  GFVD V  L      ++
Sbjct: 265 LMAASSGGYLDIVKLLLLHDADVNSQSAT---GNTALTYACAGGFVDIVKVLLN-EGANI 320

Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
              +  G+T L+ AA AGH  +   LL++  G++    N F  +AL  A  +G  D +R 
Sbjct: 321 EDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHS-NEFKESALTLACYKGHLDMVRF 379

Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
           L+ AGAD   +      +  E A   G V+  RL+
Sbjct: 380 LLEAGADQEHKTDEMHTALME-ACMDGHVEVARLL 413



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 42/131 (32%), Positives = 68/131 (51%), Gaps = 10/131 (7%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L  AAC  +V L   L+ RG ++EE  +    G T L+ A   G  + +VAL      ++
Sbjct: 431 LTLAACGGHVELAALLIERGANLEEVND---EGYTPLMEAAREGH-EEMVALLLAQGANI 486

Query: 149 NWQDSEGN-TALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIR 207
           N Q  E   TAL  A   G + + ++L+    G D+E   +   T LM+A+ +G  + ++
Sbjct: 487 NAQTEETQETALTLACCGGFSEVADFLIK--AGADIELGCS---TPLMEASQEGHLELVK 541

Query: 208 ALMLAGADVHA 218
            L+ +GA+VHA
Sbjct: 542 YLLASGANVHA 552



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 34/162 (20%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L+ AA A +V + R L+  G  +     ++    + L +ACY G +D V  L E    D 
Sbjct: 331 LMEAASAGHVEVARVLLDHGAGINT--HSNEFKESALTLACYKGHLDMVRFLLEAG-ADQ 387

Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFP----------------------------- 179
             +  E +TAL+ A   GH  +   LL+                                
Sbjct: 388 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLI 447

Query: 180 --GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 219
             G +LE  N  G+T LM+AA +G  + +  L+  GA+++A+
Sbjct: 448 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 489


>gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1
           [Homo sapiens]
          Length = 2542

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 63/197 (31%), Positives = 87/197 (44%), Gaps = 11/197 (5%)

Query: 48  DTRSIASDDSFYPFEDEEEHGVESAESVPEGVPESVPETATLLRAAC-ANNVGLLRTLVR 106
           DTRS+A   S     D + + V         V E   E  +LL  AC A    L + L+ 
Sbjct: 205 DTRSLAEACS-----DGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 259

Query: 107 RGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAG 166
              +VE+    ++   T L+ A   G++D +V L      DVN Q + GNTAL  A   G
Sbjct: 260 MHANVED--RGNKGDITPLMAASSGGYLD-IVKLLLLHDADVNSQSATGNTALTYACAGG 316

Query: 167 HAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMS 226
              I   LLN   G ++E  N  G T LM+AA  G  +  R L+  GA ++        S
Sbjct: 317 FVDIVKVLLN--EGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKES 374

Query: 227 PQEWATYTGRVDAVRLM 243
               A Y G +D VR +
Sbjct: 375 ALTLACYKGHLDMVRFL 391



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 6/155 (3%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L+ A+    + +++ L+     V     T   G T L  AC  GFVD V  L      ++
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSAT---GNTALTYACAGGFVDIVKVLLN-EGANI 331

Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
              +  G+T L+ AA AGH  +   LL++  G++    N F  +AL  A  +G  D +R 
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHS-NEFKESALTLACYKGHLDMVRF 390

Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
           L+ AGAD   +      +  E A   G V+  RL+
Sbjct: 391 LLEAGADQEHKTDEMHTALME-ACMDGHVEVARLL 424



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 43/155 (27%), Positives = 74/155 (47%), Gaps = 3/155 (1%)

Query: 89   LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
            L+ AA A +VG++  L+ +G  +E   +++R   T L +AC  G  + VV L      + 
Sbjct: 1092 LILAATAGHVGVVEILLDKGGDIEA--QSERTKDTPLSLACSGGRQE-VVDLLLARGANK 1148

Query: 149  NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
              ++    T L  AA  G+  I   LLN    ++    +  G + LM AAM G    ++ 
Sbjct: 1149 EHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKL 1208

Query: 209  LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
            L+  G+D++A+      +    A + GR + V L+
Sbjct: 1209 LLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 1243



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 34/162 (20%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L+ AA A +V + R L+  G  +     ++    + L +ACY G +D V  L E    D 
Sbjct: 342 LMEAASAGHVEVARVLLDHGAGINT--HSNEFKESALTLACYKGHLDMVRFLLEAG-ADQ 398

Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFP----------------------------- 179
             +  E +TAL+ A   GH  +   LL+                                
Sbjct: 399 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLI 458

Query: 180 --GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 219
             G +LE  N  G+T LM+AA +G  + +  L+  GA+++A+
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 42/138 (30%), Positives = 69/138 (50%), Gaps = 5/138 (3%)

Query: 82   SVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALA 141
            +V +   L  AA    V +++ L+  G  +  ++   + G + L++A  +G V  V  L 
Sbjct: 1152 NVSDYTPLSLAASGGYVNIIKILLNAGAEIN-SRTGSKLGISPLMLAAMNGHVPAVKLLL 1210

Query: 142  ECPHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 200
            +    D+N Q ++  NTAL  A   G A + + LL+     ++E R   G T LM+AA  
Sbjct: 1211 DMGS-DINAQIETNRNTALTLACFQGRAEVVSLLLDR--KANVEHRAKTGLTPLMEAASG 1267

Query: 201  GRTDCIRALMLAGADVHA 218
            G  +  R L+  GADV+A
Sbjct: 1268 GYAEVGRVLLDKGADVNA 1285



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 46/163 (28%), Positives = 69/163 (42%), Gaps = 10/163 (6%)

Query: 81  ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 140
           E   ETA  L A C     +   L++ G  +E    T       L+ A   G ++ V  L
Sbjct: 502 EETQETALTL-ACCGGFSEVADFLIKAGADIELGCSTP------LMEASQEGHLELVKYL 554

Query: 141 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 200
                 +V+   + G+TAL  A + GH  + + LL    G DLE  +  G T LMKAA  
Sbjct: 555 L-ASGANVHATTATGDTALTYACENGHTDVADVLLQ--AGADLEHESEGGRTPLMKAARA 611

Query: 201 GRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
           G    ++ L+  GA+V+        +    A   G +  V L+
Sbjct: 612 GHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELL 654



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 32/97 (32%), Positives = 51/97 (52%), Gaps = 3/97 (3%)

Query: 81  ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 140
           ES      L++AA A ++  ++ L+ +G +V  A  T  N  T + +AC  G +  VV L
Sbjct: 597 ESEGGRTPLMKAARAGHLCTVQFLISKGANVNRA--TANNDHTVVSLACAGGHL-AVVEL 653

Query: 141 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNY 177
                 D   +  +G+T LI AA+ GH  + +YLL+Y
Sbjct: 654 LLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDY 690



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 3/101 (2%)

Query: 144  PHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGR 202
            P VD++   +S  +TAL  A   GH  + + L+       +E R+  GFT L+ AA  G 
Sbjct: 1043 PSVDIDAHTESNHDTALTLACAGGHEELVSVLIAR--DAKIEHRDKKGFTPLILAATAGH 1100

Query: 203  TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
               +  L+  G D+ A+  R   +P   A   GR + V L+
Sbjct: 1101 VGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLL 1141



 Score = 36.2 bits (82), Expect = 0.070
 Identities = 36/154 (23%), Positives = 58/154 (37%), Gaps = 36/154 (23%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L+ A+   ++ L++ L+  G +V     T   G T L  AC +G  D    L +    D+
Sbjct: 539 LMEASQEGHLELVKYLLASGANVHATTAT---GDTALTYACENGHTDVADVLLQAG-ADL 594

Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLN-------------------------------- 176
             +   G T L+ AA+AGH     +L++                                
Sbjct: 595 EHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELL 654

Query: 177 YFPGLDLERRNAFGFTALMKAAMQGRTDCIRALM 210
              G D   R   G T L++AA  G T+ +  L+
Sbjct: 655 LAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLL 688



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 10/109 (9%)

Query: 79   VPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVV 138
            VP S     T+  AA   +      L+ RG  ++     ++ G T L +A   G  D V 
Sbjct: 1288 VPSSRDTALTI--AADKGHYKFCELLIHRGAHIDVR---NKKGNTPLWLASNGGHFDVVQ 1342

Query: 139  ALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYL---LNYFPGLDLE 184
             L +    DV+  D+   T L++A + GH  +  YL   +N FP  D+E
Sbjct: 1343 LLVQAG-ADVDAADNRKITPLMSAFRKGHVKVVQYLVKEVNQFPS-DIE 1389



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 41/161 (25%), Positives = 69/161 (42%), Gaps = 13/161 (8%)

Query: 88   TLLRAACANN-VGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAEC-PH 145
            T L  AC+     ++  L+ RG + E    +D    T L +A   G+V+ +  L      
Sbjct: 1124 TPLSLACSGGRQEVVDLLLARGANKEHRNVSDY---TPLSLAASGGYVNIIKILLNAGAE 1180

Query: 146  VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE---RRNAFGFTALMKAAMQGR 202
            ++       G + L+ AA  GH      LL+    ++ +    RN    TAL  A  QGR
Sbjct: 1181 INSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRN----TALTLACFQGR 1236

Query: 203  TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
             + +  L+   A+V  R  + G++P   A   G  +  R++
Sbjct: 1237 AEVVSLLLDRKANVEHR-AKTGLTPLMEAASGGYAEVGRVL 1276


>gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]
          Length = 2617

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 63/197 (31%), Positives = 87/197 (44%), Gaps = 11/197 (5%)

Query: 48  DTRSIASDDSFYPFEDEEEHGVESAESVPEGVPESVPETATLLRAAC-ANNVGLLRTLVR 106
           DTRS+A   S     D + + V         V E   E  +LL  AC A    L + L+ 
Sbjct: 205 DTRSLAEACS-----DGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 259

Query: 107 RGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAG 166
              +VE+    ++   T L+ A   G++D +V L      DVN Q + GNTAL  A   G
Sbjct: 260 MHANVED--RGNKGDITPLMAASSGGYLD-IVKLLLLHDADVNSQSATGNTALTYACAGG 316

Query: 167 HAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMS 226
              I   LLN   G ++E  N  G T LM+AA  G  +  R L+  GA ++        S
Sbjct: 317 FVDIVKVLLN--EGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKES 374

Query: 227 PQEWATYTGRVDAVRLM 243
               A Y G +D VR +
Sbjct: 375 ALTLACYKGHLDMVRFL 391



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 6/155 (3%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L+ A+    + +++ L+     V     T   G T L  AC  GFVD V  L      ++
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSAT---GNTALTYACAGGFVDIVKVLLN-EGANI 331

Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
              +  G+T L+ AA AGH  +   LL++  G++    N F  +AL  A  +G  D +R 
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHS-NEFKESALTLACYKGHLDMVRF 390

Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
           L+ AGAD   +      +  E A   G V+  RL+
Sbjct: 391 LLEAGADQEHKTDEMHTALME-ACMDGHVEVARLL 424



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 43/155 (27%), Positives = 74/155 (47%), Gaps = 3/155 (1%)

Query: 89   LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
            L+ AA A +VG++  L+ +G  +E   +++R   T L +AC  G  + VV L      + 
Sbjct: 1092 LILAATAGHVGVVEILLDKGGDIEA--QSERTKDTPLSLACSGGRQE-VVDLLLARGANK 1148

Query: 149  NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
              ++    T L  AA  G+  I   LLN    ++    +  G + LM AAM G    ++ 
Sbjct: 1149 EHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKL 1208

Query: 209  LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
            L+  G+D++A+      +    A + GR + V L+
Sbjct: 1209 LLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 1243



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 34/162 (20%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L+ AA A +V + R L+  G  +     ++    + L +ACY G +D V  L E    D 
Sbjct: 342 LMEAASAGHVEVARVLLDHGAGINT--HSNEFKESALTLACYKGHLDMVRFLLEAG-ADQ 398

Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFP----------------------------- 179
             +  E +TAL+ A   GH  +   LL+                                
Sbjct: 399 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLI 458

Query: 180 --GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 219
             G +LE  N  G+T LM+AA +G  + +  L+  GA+++A+
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 42/138 (30%), Positives = 69/138 (50%), Gaps = 5/138 (3%)

Query: 82   SVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALA 141
            +V +   L  AA    V +++ L+  G  +  ++   + G + L++A  +G V  V  L 
Sbjct: 1152 NVSDYTPLSLAASGGYVNIIKILLNAGAEIN-SRTGSKLGISPLMLAAMNGHVPAVKLLL 1210

Query: 142  ECPHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 200
            +    D+N Q ++  NTAL  A   G A + + LL+     ++E R   G T LM+AA  
Sbjct: 1211 DMGS-DINAQIETNRNTALTLACFQGRAEVVSLLLDR--KANVEHRAKTGLTPLMEAASG 1267

Query: 201  GRTDCIRALMLAGADVHA 218
            G  +  R L+  GADV+A
Sbjct: 1268 GYAEVGRVLLDKGADVNA 1285



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 46/163 (28%), Positives = 69/163 (42%), Gaps = 10/163 (6%)

Query: 81  ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 140
           E   ETA  L A C     +   L++ G  +E    T       L+ A   G ++ V  L
Sbjct: 502 EETQETALTL-ACCGGFSEVADFLIKAGADIELGCSTP------LMEASQEGHLELVKYL 554

Query: 141 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 200
                 +V+   + G+TAL  A + GH  + + LL    G DLE  +  G T LMKAA  
Sbjct: 555 L-ASGANVHATTATGDTALTYACENGHTDVADVLLQ--AGADLEHESEGGRTPLMKAARA 611

Query: 201 GRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
           G    ++ L+  GA+V+        +    A   G +  V L+
Sbjct: 612 GHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELL 654



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 32/97 (32%), Positives = 51/97 (52%), Gaps = 3/97 (3%)

Query: 81  ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 140
           ES      L++AA A ++  ++ L+ +G +V  A  T  N  T + +AC  G +  VV L
Sbjct: 597 ESEGGRTPLMKAARAGHLCTVQFLISKGANVNRA--TANNDHTVVSLACAGGHL-AVVEL 653

Query: 141 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNY 177
                 D   +  +G+T LI AA+ GH  + +YLL+Y
Sbjct: 654 LLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDY 690



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 3/101 (2%)

Query: 144  PHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGR 202
            P VD++   +S  +TAL  A   GH  + + L+       +E R+  GFT L+ AA  G 
Sbjct: 1043 PSVDIDAHTESNHDTALTLACAGGHEELVSVLIAR--DAKIEHRDKKGFTPLILAATAGH 1100

Query: 203  TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
               +  L+  G D+ A+  R   +P   A   GR + V L+
Sbjct: 1101 VGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLL 1141



 Score = 36.2 bits (82), Expect = 0.070
 Identities = 36/154 (23%), Positives = 58/154 (37%), Gaps = 36/154 (23%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L+ A+   ++ L++ L+  G +V     T   G T L  AC +G  D    L +    D+
Sbjct: 539 LMEASQEGHLELVKYLLASGANVHATTAT---GDTALTYACENGHTDVADVLLQAG-ADL 594

Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLN-------------------------------- 176
             +   G T L+ AA+AGH     +L++                                
Sbjct: 595 EHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELL 654

Query: 177 YFPGLDLERRNAFGFTALMKAAMQGRTDCIRALM 210
              G D   R   G T L++AA  G T+ +  L+
Sbjct: 655 LAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLL 688



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 10/109 (9%)

Query: 79   VPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVV 138
            VP S     T+  AA   +      L+ RG  ++     ++ G T L +A   G  D V 
Sbjct: 1288 VPSSRDTALTI--AADKGHYKFCELLIHRGAHIDVR---NKKGNTPLWLASNGGHFDVVQ 1342

Query: 139  ALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYL---LNYFPGLDLE 184
             L +    DV+  D+   T L++A + GH  +  YL   +N FP  D+E
Sbjct: 1343 LLVQAG-ADVDAADNRKITPLMSAFRKGHVKVVQYLVKEVNQFPS-DIE 1389



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 41/161 (25%), Positives = 69/161 (42%), Gaps = 13/161 (8%)

Query: 88   TLLRAACANN-VGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAEC-PH 145
            T L  AC+     ++  L+ RG + E    +D    T L +A   G+V+ +  L      
Sbjct: 1124 TPLSLACSGGRQEVVDLLLARGANKEHRNVSDY---TPLSLAASGGYVNIIKILLNAGAE 1180

Query: 146  VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE---RRNAFGFTALMKAAMQGR 202
            ++       G + L+ AA  GH      LL+    ++ +    RN    TAL  A  QGR
Sbjct: 1181 INSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRN----TALTLACFQGR 1236

Query: 203  TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
             + +  L+   A+V  R  + G++P   A   G  +  R++
Sbjct: 1237 AEVVSLLLDRKANVEHR-AKTGLTPLMEAASGGYAEVGRVL 1276


>gi|169208819 PREDICTED: similar to kinase D-interacting substrate
           220 [Homo sapiens]
          Length = 380

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 86/315 (27%), Positives = 124/315 (39%), Gaps = 28/315 (8%)

Query: 101 LRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALI 160
           +R L+ +G +V      D  GRT L +AC  G +D V  L +    D    DS GN+ ++
Sbjct: 67  VRLLLEQGAAVNLR---DERGRTALSLACERGHLDAVQLLVQFSG-DPEAADSAGNSPVM 122

Query: 161 TAAQAGHAIITNYLLNYFP--GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHA 218
            AA  GH  +  +L+  F   GL L+R N  G TAL  AA +G   C++AL        A
Sbjct: 123 WAAACGHGAVLEFLVRSFRRLGLRLDRTNRAGLTALQLAAARGHGTCVQALTGPWGRAAA 182

Query: 219 RDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKN 278
               RG +     +  GR       +    RP P +     RP L     AA    G   
Sbjct: 183 AAAARGSNSD---SPPGRPAPAASPEH--RRPSPRRL---PRPLLARFARAAGGHGGEAG 234

Query: 279 CLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKR 338
              + +    +  + R    PE G  +   +   T   +  +        P SP S G  
Sbjct: 235 SAGKNSGRHRAQGSER----PELGRSMSLALGAVTEEEAARLRAGALMALPNSPQSSGTG 290

Query: 339 RLAVQEILAA---RAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALG-SR 394
           R   QE+L       A+ P        GG G  GR G      R  S    +P  +G + 
Sbjct: 291 RWRSQEVLEGAPPTLAQAPIGLSPHPEGGPGS-GRLG-----LRRRSTAPDIPSLVGEAP 344

Query: 395 GPAAPAPRKASLLPL 409
           GP +    +A+ LP+
Sbjct: 345 GPESGPELEANALPV 359


>gi|169208593 PREDICTED: similar to kinase D-interacting substrate
           220 [Homo sapiens]
          Length = 380

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 86/315 (27%), Positives = 124/315 (39%), Gaps = 28/315 (8%)

Query: 101 LRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALI 160
           +R L+ +G +V      D  GRT L +AC  G +D V  L +    D    DS GN+ ++
Sbjct: 67  VRLLLEQGAAVNLR---DERGRTALSLACERGHLDAVQLLVQFSG-DPEAADSAGNSPVM 122

Query: 161 TAAQAGHAIITNYLLNYFP--GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHA 218
            AA  GH  +  +L+  F   GL L+R N  G TAL  AA +G   C++AL        A
Sbjct: 123 WAAACGHGAVLEFLVRSFRRLGLRLDRTNRAGLTALQLAAARGHGTCVQALTGPWGRAAA 182

Query: 219 RDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKN 278
               RG +     +  GR       +    RP P +     RP L     AA    G   
Sbjct: 183 AAAARGSNSD---SPPGRPAPAASPEH--RRPSPRRL---PRPLLARFARAAGGHGGEAG 234

Query: 279 CLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKR 338
              + +    +  + R    PE G  +   +   T   +  +        P SP S G  
Sbjct: 235 SAGKNSGRHRAQGSER----PELGRSMSLALGAVTEEEAARLRAGALMALPNSPQSSGTG 290

Query: 339 RLAVQEILAA---RAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALG-SR 394
           R   QE+L       A+ P        GG G  GR G      R  S    +P  +G + 
Sbjct: 291 RWRSQEVLEGAPPTLAQAPIGLSPHPEGGPGS-GRLG-----LRRRSTAPDIPSLVGEAP 344

Query: 395 GPAAPAPRKASLLPL 409
           GP +    +A+ LP+
Sbjct: 345 GPESGPELEANALPV 359


>gi|55741641 kinase D-interacting substrate of 220 kDa [Homo
           sapiens]
          Length = 1771

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 61/187 (32%), Positives = 91/187 (48%), Gaps = 14/187 (7%)

Query: 97  NVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGN 156
           N+  L+ L+ +   V+E  E    G+T L++A   G ++ V  L +    + N +D +  
Sbjct: 17  NIPALKALLEKCKDVDERNEC---GQTPLMIAAEQGNLEIVKELIK-NGANCNLEDLDNW 72

Query: 157 TALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADV 216
           TALI+A++ GH  I   LL    G++LE R+  G+TALM A  +GRTD +  L+  GA+ 
Sbjct: 73  TALISASKEGHVHIVEELLKC--GVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANP 130

Query: 217 HARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGS 276
                   + P  WA   G  D V L   LL+        +KY     P   AARK  G 
Sbjct: 131 SVTG-LYSVYPIIWAAGRGHADIVHL---LLQNGAKVNCSDKY--GTTPLVWAARK--GH 182

Query: 277 KNCLQRL 283
             C++ L
Sbjct: 183 LECVKHL 189



 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 46/156 (29%), Positives = 76/156 (48%), Gaps = 7/156 (4%)

Query: 86  TATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPH 145
           T  L+ AA   ++  ++ L+  G  V++      N  T LIVA   G+  +V  + +  +
Sbjct: 171 TTPLVWAARKGHLECVKHLLAMGADVDQE---GANSMTALIVAVKGGYTQSVKEILK-RN 226

Query: 146 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDC 205
            +VN  D +GNTAL+ A++ GH  I   LL+    +++  R+  G T L+ A   G  + 
Sbjct: 227 PNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRS--GDTVLIGAVRGGHVEI 284

Query: 206 IRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVR 241
           +RAL+   AD+  R  +   +   WA   G    VR
Sbjct: 285 VRALLQKYADIDIRG-QDNKTALYWAVEKGNATMVR 319



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 43/137 (31%), Positives = 68/137 (49%), Gaps = 8/137 (5%)

Query: 81  ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTV-VA 139
           E +     L+ A+   +V ++  L++ GV++E     D  G T L+ ACY G  D V + 
Sbjct: 67  EDLDNWTALISASKEGHVHIVEELLKCGVNLEHR---DMGGWTALMWACYKGRTDVVELL 123

Query: 140 LAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAM 199
           L+   +  V    S     +I AA  GHA I + LL    G  +   + +G T L+ AA 
Sbjct: 124 LSHGANPSVTGLYSV--YPIIWAAGRGHADIVHLLLQN--GAKVNCSDKYGTTPLVWAAR 179

Query: 200 QGRTDCIRALMLAGADV 216
           +G  +C++ L+  GADV
Sbjct: 180 KGHLECVKHLLAMGADV 196



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 42/133 (31%), Positives = 64/133 (48%), Gaps = 7/133 (5%)

Query: 118 DRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNY 177
           DR+G T LI A   G V+ V AL +  + D++ +  +  TAL  A + G+A +   +L  
Sbjct: 266 DRSGDTVLIGAVRGGHVEIVRALLQ-KYADIDIRGQDNKTALYWAVEKGNATMVRDILQC 324

Query: 178 FPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRV 237
            P  D E     G T L+KA      + +  L+  GA V A D ++G +P   A    R 
Sbjct: 325 NP--DTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVD-KKGDTPLHIAI---RG 378

Query: 238 DAVRLMQRLLERP 250
            + +L + LL  P
Sbjct: 379 RSRKLAELLLRNP 391


>gi|70995267 ankyrin repeat domain 29 [Homo sapiens]
          Length = 301

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 50/152 (32%), Positives = 73/152 (48%), Gaps = 6/152 (3%)

Query: 92  AACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQ 151
           AA   N+ LL+ L+  G    + +  D +G T L+VA Y G +D V  L      D+N Q
Sbjct: 19  AARRGNLALLKLLLNSGRVDVDCR--DSHGTTLLMVAAYAGHIDCVRELV-LQGADINLQ 75

Query: 152 DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALML 211
              G TAL  AAQ GH  +  +L  +  G   E R   G TAL+ A+  G    +  L+ 
Sbjct: 76  RESGTTALFFAAQQGHNDVVRFLFGF--GASTEFRTKDGGTALLAASQYGHMQVVETLLK 133

Query: 212 AGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
            GA++H +    G +    A   G +D +RL+
Sbjct: 134 HGANIHDQ-LYDGATALFLAAQGGYLDVIRLL 164



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 52/159 (32%), Positives = 78/159 (49%), Gaps = 9/159 (5%)

Query: 86  TATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPH 145
           T  L+ AA A ++  +R LV +G  +   +E+   G T L  A   G  D V  L     
Sbjct: 47  TTLLMVAAYAGHIDCVRELVLQGADINLQRES---GTTALFFAAQQGHNDVVRFLFGFG- 102

Query: 146 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDC 205
               ++  +G TAL+ A+Q GH  +   LL +  G ++  +   G TAL  AA  G  D 
Sbjct: 103 ASTEFRTKDGGTALLAASQYGHMQVVETLLKH--GANIHDQLYDGATALFLAAQGGYLDV 160

Query: 206 IRALMLAGADVHARDPRR-GMSPQEWATYTGRVDAVRLM 243
           IR L+ +GA V+   PR+ G +P   A+  G  + VR+M
Sbjct: 161 IRLLLASGAKVN--QPRQDGTAPLWIASQMGHSEVVRVM 197



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 42/155 (27%), Positives = 72/155 (46%), Gaps = 8/155 (5%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           LL A+   ++ ++ TL++ G ++ +      +G T L +A   G++D V+ L       V
Sbjct: 116 LLAASQYGHMQVVETLLKHGANIHDQLY---DGATALFLAAQGGYLD-VIRLLLASGAKV 171

Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
           N    +G   L  A+Q GH+ +   +L    G D +     G TAL+KAA +G  D I+ 
Sbjct: 172 NQPRQDGTAPLWIASQMGHSEVVRVML--LRGADRDAARNDGTTALLKAANKGYNDVIKE 229

Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
           L+     +     + G S    A  +G +  V L+
Sbjct: 230 LLKFSPTLGIL--KNGTSALHAAVLSGNIKTVALL 262



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 2/86 (2%)

Query: 158 ALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVH 217
           A   AA+ G+  +   LLN    +D++ R++ G T LM AA  G  DC+R L+L GAD++
Sbjct: 15  AAFWAARRGNLALLKLLLNS-GRVDVDCRDSHGTTLLMVAAYAGHIDCVRELVLQGADIN 73

Query: 218 ARDPRRGMSPQEWATYTGRVDAVRLM 243
            +    G +   +A   G  D VR +
Sbjct: 74  LQ-RESGTTALFFAAQQGHNDVVRFL 98


>gi|169208169 PREDICTED: similar to kinase D-interacting substrate
           220 [Homo sapiens]
          Length = 380

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 86/317 (27%), Positives = 119/317 (37%), Gaps = 31/317 (9%)

Query: 101 LRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALI 160
           +R L+ +G +V      D  GRT L +AC  G +D V  L +    D    DS GN+ ++
Sbjct: 67  VRLLLEQGAAVNLR---DERGRTALSLACERGHLDAVQLLVQFSG-DPEAADSAGNSPVM 122

Query: 161 TAAQAGHAIITNYLLNYFP--GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHA 218
            AA  GH  +  +L+  F   GL L+R N  G TAL  AA +G   C++AL        A
Sbjct: 123 WAAACGHGAVLEFLVRSFRRLGLRLDRTNRAGLTALQLAAARGHGTCVQALTGPWGRAAA 182

Query: 219 RDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKN 278
               RG +     +  GR       +    RP P +     RP L     AA    G   
Sbjct: 183 AAAARGSNSD---SPPGRPAPAASPEH--RRPSPRRL---PRPLLARFARAAGGHGGEAG 234

Query: 279 CLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKR 338
              + +    +  + R    PE G  +   +   T   +  +        P SP S G  
Sbjct: 235 SAGKNSGRHRAQGSER----PELGRSMSLALGAVTEEEAARLRAGALMALPNSPQSSGTG 290

Query: 339 RLAVQEILAA---RAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRG 395
           R   QE+L       A+ P        GG G  GR G      R  S    +P  +G   
Sbjct: 291 RWRSQEVLEGAPPTLAQAPIGLSPHPEGGPGS-GRLG-----LRRRSTAPDIPSLVGE-- 342

Query: 396 PAAPAPRKASLLPLQRL 412
             AP P     L    L
Sbjct: 343 --APGPESGPELEANAL 357


>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
          Length = 983

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)

Query: 114 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 172
           A+  D +G+T L  A   G +  V  L  C H   +N +D +GN  L+ A Q GH+ I +
Sbjct: 115 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 172

Query: 173 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 220
           +LL++  G D+  RN  G TALM A   G ++ + AL+  GAD++  D
Sbjct: 173 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 218



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)

Query: 125 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 184
           L+ A  +G  + V +L           DSEG TA   AA  GH      ++ +  G+D+ 
Sbjct: 26  LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 83

Query: 185 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
            ++  G +AL  AA     +CIR L+ +     + D   G +   +A   G + AV+++
Sbjct: 84  AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 141



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)

Query: 153 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 212
           ++ +  L+ A + G A     LL    G    + ++ G TA   AA +G  +C+R ++  
Sbjct: 20  NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 78

Query: 213 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 272
           G DV A+D   G S    A      + +R   +LL+  CP +        +    + A  
Sbjct: 79  GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 127

Query: 273 PAGSKNCLQ 281
            A ++ CLQ
Sbjct: 128 YAAAQGCLQ 136



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 1/64 (1%)

Query: 113 EAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITN 172
           +    +++GRT L++AC  G  + V AL +    D+N  DS G  AL  +  + +A I +
Sbjct: 180 DVNSRNKSGRTALMLACEIGSSNAVEALIK-KGADLNLVDSLGYNALHYSKLSENAGIQS 238

Query: 173 YLLN 176
            LL+
Sbjct: 239 LLLS 242


>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
          Length = 972

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)

Query: 114 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 172
           A+  D +G+T L  A   G +  V  L  C H   +N +D +GN  L+ A Q GH+ I +
Sbjct: 104 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 161

Query: 173 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 220
           +LL++  G D+  RN  G TALM A   G ++ + AL+  GAD++  D
Sbjct: 162 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 207



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)

Query: 125 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 184
           L+ A  +G  + V +L           DSEG TA   AA  GH      ++ +  G+D+ 
Sbjct: 15  LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 72

Query: 185 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
            ++  G +AL  AA     +CIR L+ +     + D   G +   +A   G + AV+++
Sbjct: 73  AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 130



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)

Query: 153 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 212
           ++ +  L+ A + G A     LL    G    + ++ G TA   AA +G  +C+R ++  
Sbjct: 9   NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 67

Query: 213 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 272
           G DV A+D   G S    A      + +R   +LL+  CP +        +    + A  
Sbjct: 68  GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 116

Query: 273 PAGSKNCLQ 281
            A ++ CLQ
Sbjct: 117 YAAAQGCLQ 125



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 1/64 (1%)

Query: 113 EAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITN 172
           +    +++GRT L++AC  G  + V AL +    D+N  DS G  AL  +  + +A I +
Sbjct: 169 DVNSRNKSGRTALMLACEIGSSNAVEALIK-KGADLNLVDSLGYNALHYSKLSENAGIQS 227

Query: 173 YLLN 176
            LL+
Sbjct: 228 LLLS 231


>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
          Length = 951

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)

Query: 114 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 172
           A+  D +G+T L  A   G +  V  L  C H   +N +D +GN  L+ A Q GH+ I +
Sbjct: 112 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 169

Query: 173 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 220
           +LL++  G D+  RN  G TALM A   G ++ + AL+  GAD++  D
Sbjct: 170 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 215



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)

Query: 125 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 184
           L+ A  +G  + V +L           DSEG TA   AA  GH      ++ +  G+D+ 
Sbjct: 23  LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 80

Query: 185 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
            ++  G +AL  AA     +CIR L+ +     + D   G +   +A   G + AV+++
Sbjct: 81  AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 138



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)

Query: 153 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 212
           ++ +  L+ A + G A     LL    G    + ++ G TA   AA +G  +C+R ++  
Sbjct: 17  NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 75

Query: 213 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 272
           G DV A+D   G S    A      + +R   +LL+  CP +        +    + A  
Sbjct: 76  GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 124

Query: 273 PAGSKNCLQ 281
            A ++ CLQ
Sbjct: 125 YAAAQGCLQ 133



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 1/64 (1%)

Query: 113 EAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITN 172
           +    +++GRT L++AC  G  + V AL +    D+N  DS G  AL  +  + +A I +
Sbjct: 177 DVNSRNKSGRTALMLACEIGSSNAVEALIK-KGADLNLVDSLGYNALHYSKLSENAGIQS 235

Query: 173 YLLN 176
            LL+
Sbjct: 236 LLLS 239


>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)

Query: 114 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 172
           A+  D +G+T L  A   G +  V  L  C H   +N +D +GN  L+ A Q GH+ I +
Sbjct: 112 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 169

Query: 173 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 220
           +LL++  G D+  RN  G TALM A   G ++ + AL+  GAD++  D
Sbjct: 170 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 215



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)

Query: 125 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 184
           L+ A  +G  + V +L           DSEG TA   AA  GH      ++ +  G+D+ 
Sbjct: 23  LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 80

Query: 185 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
            ++  G +AL  AA     +CIR L+ +     + D   G +   +A   G + AV+++
Sbjct: 81  AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 138



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)

Query: 153 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 212
           ++ +  L+ A + G A     LL    G    + ++ G TA   AA +G  +C+R ++  
Sbjct: 17  NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 75

Query: 213 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 272
           G DV A+D   G S    A      + +R   +LL+  CP +        +    + A  
Sbjct: 76  GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 124

Query: 273 PAGSKNCLQ 281
            A ++ CLQ
Sbjct: 125 YAAAQGCLQ 133



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 1/64 (1%)

Query: 113 EAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITN 172
           +    +++GRT L++AC  G  + V AL +    D+N  DS G  AL  +  + +A I +
Sbjct: 177 DVNSRNKSGRTALMLACEIGSSNAVEALIK-KGADLNLVDSLGYNALHYSKLSENAGIQS 235

Query: 173 YLLN 176
            LL+
Sbjct: 236 LLLS 239


>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)

Query: 114 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 172
           A+  D +G+T L  A   G +  V  L  C H   +N +D +GN  L+ A Q GH+ I +
Sbjct: 112 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 169

Query: 173 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 220
           +LL++  G D+  RN  G TALM A   G ++ + AL+  GAD++  D
Sbjct: 170 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 215



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)

Query: 125 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 184
           L+ A  +G  + V +L           DSEG TA   AA  GH      ++ +  G+D+ 
Sbjct: 23  LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 80

Query: 185 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
            ++  G +AL  AA     +CIR L+ +     + D   G +   +A   G + AV+++
Sbjct: 81  AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 138



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)

Query: 153 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 212
           ++ +  L+ A + G A     LL    G    + ++ G TA   AA +G  +C+R ++  
Sbjct: 17  NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 75

Query: 213 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 272
           G DV A+D   G S    A      + +R   +LL+  CP +        +    + A  
Sbjct: 76  GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 124

Query: 273 PAGSKNCLQ 281
            A ++ CLQ
Sbjct: 125 YAAAQGCLQ 133



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 1/64 (1%)

Query: 113 EAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITN 172
           +    +++GRT L++AC  G  + V AL +    D+N  DS G  AL  +  + +A I +
Sbjct: 177 DVNSRNKSGRTALMLACEIGSSNAVEALIK-KGADLNLVDSLGYNALHYSKLSENAGIQS 235

Query: 173 YLLN 176
            LL+
Sbjct: 236 LLLS 239


>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)

Query: 114 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 172
           A+  D +G+T L  A   G +  V  L  C H   +N +D +GN  L+ A Q GH+ I +
Sbjct: 112 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 169

Query: 173 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 220
           +LL++  G D+  RN  G TALM A   G ++ + AL+  GAD++  D
Sbjct: 170 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 215



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)

Query: 125 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 184
           L+ A  +G  + V +L           DSEG TA   AA  GH      ++ +  G+D+ 
Sbjct: 23  LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 80

Query: 185 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
            ++  G +AL  AA     +CIR L+ +     + D   G +   +A   G + AV+++
Sbjct: 81  AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 138



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)

Query: 153 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 212
           ++ +  L+ A + G A     LL    G    + ++ G TA   AA +G  +C+R ++  
Sbjct: 17  NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 75

Query: 213 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 272
           G DV A+D   G S    A      + +R   +LL+  CP +        +    + A  
Sbjct: 76  GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 124

Query: 273 PAGSKNCLQ 281
            A ++ CLQ
Sbjct: 125 YAAAQGCLQ 133



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 1/64 (1%)

Query: 113 EAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITN 172
           +    +++GRT L++AC  G  + V AL +    D+N  DS G  AL  +  + +A I +
Sbjct: 177 DVNSRNKSGRTALMLACEIGSSNAVEALIK-KGADLNLVDSLGYNALHYSKLSENAGIQS 235

Query: 173 YLLN 176
            LL+
Sbjct: 236 LLLS 239


>gi|110431370 espin [Homo sapiens]
          Length = 854

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 50/173 (28%), Positives = 81/173 (46%), Gaps = 7/173 (4%)

Query: 73  ESVPEGVPESVPETATLLRAACAN-NVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYH 131
           E  PEGV       AT L  AC   ++ + + LV+   +   A+  D  G T L  A   
Sbjct: 159 EHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHARAHD--GMTPLHAAAQM 216

Query: 132 GFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGF 191
           G    +V L  C  V ++ QD +G TA+  AA  GH  + ++LL +   +  +    +G 
Sbjct: 217 GHSPVIVWLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEISAD---LWGG 273

Query: 192 TALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQ 244
           T L  AA  G  +C + L++ GA++  RD R G +  + + + G     R ++
Sbjct: 274 TPLHDAAENGELECCQILVVNGAELDVRD-RDGYTAADLSDFNGHSHCTRYLR 325



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 36/136 (26%), Positives = 57/136 (41%), Gaps = 25/136 (18%)

Query: 383 PRAGLPPAL-GSRGPAAPA-PRKASLLPLQRLRRRSVRPGVVVP----RVRVSKAPAPTF 436
           P AG  P L GS  P  P  P     L ++ L       G  +P    +V V K      
Sbjct: 708 PAAGFQPLLNGSLVPVPPTTPAPGVQLDVEALIPTHDEQGRPIPEWKRQVMVRKMQLKMQ 767

Query: 437 QPERPARKGSTKDSGHLQIPKWR-------YKEAKEEKRKAEEAEKKRQAEAQKER---- 485
           + E   RK   +++    +P WR        +E +E+KRK EE +K+ +   +KE+    
Sbjct: 768 EEEEQRRKEEEEEARLASMPAWRRDLLRKKLEEEREQKRKEEERQKQEELRREKEQSEKL 827

Query: 486 --------RTAPWKKR 493
                   + APW+++
Sbjct: 828 RTLGYDESKLAPWQRQ 843



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 39/152 (25%), Positives = 61/152 (40%), Gaps = 3/152 (1%)

Query: 92  AACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQ 151
           AA A  +  LR LV        A+   RNG T    A   G +  +  L       V  +
Sbjct: 43  AARAGKLHCLRFLVEEAALPAAARA--RNGATPAHDASATGHLACLQWLLSQGGCRVQDK 100

Query: 152 DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALML 211
           D+ G T L  AA+ GH  + N+LL++  G D       G   +  AA +G    +R L+ 
Sbjct: 101 DNSGATVLHLAARFGHPEVVNWLLHHGGG-DPTAATDMGALPIHYAAAKGDFPSLRLLVE 159

Query: 212 AGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
              +      + G +P   A   G ++  + +
Sbjct: 160 HYPEGVNAQTKNGATPLYLACQEGHLEVTQYL 191


>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
          Length = 2603

 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 53/159 (33%), Positives = 78/159 (49%), Gaps = 9/159 (5%)

Query: 88   TLLRAACAN-NVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHV 146
            T L  ACA  +  L++TL+ RG S+E     D+ G T LI+A   G V  V  L +    
Sbjct: 1085 TALTLACAGGHEELVQTLLERGASIE---HRDKKGFTPLILAATAGHVGVVEILLD-NGA 1140

Query: 147  DVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDC 205
            D+  Q +   +T L  A   G   +   LL    G + E RN   +T L  AA  G  + 
Sbjct: 1141 DIEAQSERTKDTPLSLACSGGRQEVVELLL--ARGANKEHRNVSDYTPLSLAASGGYVNI 1198

Query: 206  IRALMLAGADVHAR-DPRRGMSPQEWATYTGRVDAVRLM 243
            I+ L+ AGA++++R   + G+SP   A   G   AV+L+
Sbjct: 1199 IKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLL 1237



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 46/155 (29%), Positives = 69/155 (44%), Gaps = 6/155 (3%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L+ AA   +V +++ L+     V     T   G T L  AC  G+VD V  L E     +
Sbjct: 305 LMAAANGGHVKIVKLLLAHKADVNAQSST---GNTALTYACAGGYVDVVKVLLESG-ASI 360

Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
              +  G+T L+ A  AGH  +   LL    G++    N F  +AL  A  +G  + +R 
Sbjct: 361 EDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHS-NEFKESALTLACYKGHLEMVRF 419

Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
           L+ AGAD   +      +  E A   G V+  RL+
Sbjct: 420 LLEAGADQEHKTDEMHTALME-ACMDGHVEVARLL 453



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 44/155 (28%), Positives = 74/155 (47%), Gaps = 3/155 (1%)

Query: 89   LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
            L+ AA A +VG++  L+  G  +E   +++R   T L +AC  G  + VV L      + 
Sbjct: 1120 LILAATAGHVGVVEILLDNGADIEA--QSERTKDTPLSLACSGGRQE-VVELLLARGANK 1176

Query: 149  NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
              ++    T L  AA  G+  I   LLN    ++    +  G + LM AAM G T  ++ 
Sbjct: 1177 EHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKL 1236

Query: 209  LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
            L+  G+D++A+      +    A + GR + V L+
Sbjct: 1237 LLDMGSDINAQIETNRNTALTLACFQGRTEVVSLL 1271



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 52/166 (31%), Positives = 71/166 (42%), Gaps = 6/166 (3%)

Query: 79  VPESVPETATLLRAAC-ANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTV 137
           V E   E  +LL  AC A    L + L+    +VE+     +   T L+ A   G V  +
Sbjct: 260 VNEHTEEGESLLCLACSAGYYELAQVLLAMHANVED--RGIKGDITPLMAAANGGHVK-I 316

Query: 138 VALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKA 197
           V L      DVN Q S GNTAL  A   G+  +   LL    G  +E  N  G T LM+A
Sbjct: 317 VKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLE--SGASIEDHNENGHTPLMEA 374

Query: 198 AMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
              G  +  R L+  GA ++        S    A Y G ++ VR +
Sbjct: 375 GSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFL 420



 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 45/131 (34%), Positives = 67/131 (51%), Gaps = 10/131 (7%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L  AAC  +V L   L+ RG S+EE  +    G T L+ A   G  + +VAL      ++
Sbjct: 471 LTLAACGGHVELAALLIERGASLEEVND---EGYTPLMEAAREGH-EEMVALLLGQGANI 526

Query: 149 NWQDSEGN-TALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIR 207
           N Q  E   TAL  A   G   + ++L+    G D+E   +   T LM+AA +G  + ++
Sbjct: 527 NAQTEETQETALTLACCGGFLEVADFLIK--AGADIELGCS---TPLMEAAQEGHLELVK 581

Query: 208 ALMLAGADVHA 218
            L+ AGA+VHA
Sbjct: 582 YLLAAGANVHA 592



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 34/101 (33%), Positives = 50/101 (49%), Gaps = 3/101 (2%)

Query: 144  PHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGR 202
            P +D++ Q +S  +TAL  A   GH  +   LL    G  +E R+  GFT L+ AA  G 
Sbjct: 1071 PAIDIDAQTESNHDTALTLACAGGHEELVQTLLER--GASIEHRDKKGFTPLILAATAGH 1128

Query: 203  TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
               +  L+  GAD+ A+  R   +P   A   GR + V L+
Sbjct: 1129 VGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELL 1169



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 51/197 (25%), Positives = 81/197 (41%), Gaps = 17/197 (8%)

Query: 54  SDDSFYPFEDEEEHGVESAESVPEGV-------PESVPETATLLRAACANNVGLLRTLVR 106
           +D+ + P  +    G E   ++  G         E   ETA  L A C   + +   L++
Sbjct: 497 NDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTL-ACCGGFLEVADFLIK 555

Query: 107 RGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAG 166
            G  +E    T       L+ A   G ++ V  L      +V+   + G+TAL  A + G
Sbjct: 556 AGADIELGCSTP------LMEAAQEGHLELVKYLLAAG-ANVHATTATGDTALTYACENG 608

Query: 167 HAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMS 226
           H  + + LL    G DLE  +  G T LMKAA  G    ++ L+  GA+V+        +
Sbjct: 609 HTDVADVLLQ--AGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHT 666

Query: 227 PQEWATYTGRVDAVRLM 243
               A   G +  V L+
Sbjct: 667 VLSLACAGGHLAVVELL 683



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 40/162 (24%), Positives = 66/162 (40%), Gaps = 34/162 (20%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L+ A  A +V + R L+  G  +     ++    + L +ACY G ++ V  L E    D 
Sbjct: 371 LMEAGSAGHVEVARLLLENGAGINT--HSNEFKESALTLACYKGHLEMVRFLLEAG-ADQ 427

Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFP----------------------------- 179
             +  E +TAL+ A   GH  +   LL+                                
Sbjct: 428 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLI 487

Query: 180 --GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 219
             G  LE  N  G+T LM+AA +G  + +  L+  GA+++A+
Sbjct: 488 ERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQ 529



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 3/97 (3%)

Query: 81  ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 140
           ES      L++AA A +V  ++ L+ +G +V     T  N  T L +AC  G +  VV L
Sbjct: 626 ESEGGRTPLMKAARAGHVCTVQFLISKGANVNRT--TANNDHTVLSLACAGGHL-AVVEL 682

Query: 141 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNY 177
                 D   +  +G+T LI AA+ GH  +  YLL+Y
Sbjct: 683 LLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDY 719



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 5/138 (3%)

Query: 82   SVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALA 141
            +V +   L  AA    V +++ L+  G  +  ++   + G + L++A  +G    V  L 
Sbjct: 1180 NVSDYTPLSLAASGGYVNIIKILLNAGAEIN-SRTGSKLGISPLMLAAMNGHTAAVKLLL 1238

Query: 142  ECPHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 200
            +    D+N Q ++  NTAL  A   G   + + LL+     ++E R   G T LM+AA  
Sbjct: 1239 DMGS-DINAQIETNRNTALTLACFQGRTEVVSLLLDR--KANVEHRAKTGLTPLMEAASG 1295

Query: 201  GRTDCIRALMLAGADVHA 218
            G  +  R L+  GADV+A
Sbjct: 1296 GYAEVGRVLLDKGADVNA 1313



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 42/161 (26%), Positives = 70/161 (43%), Gaps = 13/161 (8%)

Query: 88   TLLRAACANN-VGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAEC-PH 145
            T L  AC+     ++  L+ RG + E    +D    T L +A   G+V+ +  L      
Sbjct: 1152 TPLSLACSGGRQEVVELLLARGANKEHRNVSDY---TPLSLAASGGYVNIIKILLNAGAE 1208

Query: 146  VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE---RRNAFGFTALMKAAMQGR 202
            ++       G + L+ AA  GH      LL+    ++ +    RN    TAL  A  QGR
Sbjct: 1209 INSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRN----TALTLACFQGR 1264

Query: 203  TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
            T+ +  L+   A+V  R  + G++P   A   G  +  R++
Sbjct: 1265 TEVVSLLLDRKANVEHR-AKTGLTPLMEAASGGYAEVGRVL 1304



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 9/104 (8%)

Query: 79   VPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVV 138
            VP S     T+  AA   +      L+ RG  ++     ++ G T L +A   G +D V 
Sbjct: 1316 VPSSRDTALTI--AADKGHYKFCELLIGRGAHIDVR---NKKGNTPLWLAANGGHLDVVQ 1370

Query: 139  ALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYL---LNYFP 179
             L +    DV+  D+   T L+ A + GH  +  YL   +N FP
Sbjct: 1371 LLVQAG-ADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFP 1413


>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo
           sapiens]
          Length = 2352

 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 53/159 (33%), Positives = 78/159 (49%), Gaps = 9/159 (5%)

Query: 88  TLLRAACAN-NVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHV 146
           T L  ACA  +  L++TL+ RG S+E     D+ G T LI+A   G V  V  L +    
Sbjct: 834 TALTLACAGGHEELVQTLLERGASIE---HRDKKGFTPLILAATAGHVGVVEILLD-NGA 889

Query: 147 DVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDC 205
           D+  Q +   +T L  A   G   +   LL    G + E RN   +T L  AA  G  + 
Sbjct: 890 DIEAQSERTKDTPLSLACSGGRQEVVELLL--ARGANKEHRNVSDYTPLSLAASGGYVNI 947

Query: 206 IRALMLAGADVHAR-DPRRGMSPQEWATYTGRVDAVRLM 243
           I+ L+ AGA++++R   + G+SP   A   G   AV+L+
Sbjct: 948 IKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLL 986



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 46/155 (29%), Positives = 69/155 (44%), Gaps = 6/155 (3%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L+ AA   +V +++ L+     V     T   G T L  AC  G+VD V  L E     +
Sbjct: 305 LMAAANGGHVKIVKLLLAHKADVNAQSST---GNTALTYACAGGYVDVVKVLLESG-ASI 360

Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
              +  G+T L+ A  AGH  +   LL    G++    N F  +AL  A  +G  + +R 
Sbjct: 361 EDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHS-NEFKESALTLACYKGHLEMVRF 419

Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
           L+ AGAD   +      +  E A   G V+  RL+
Sbjct: 420 LLEAGADQEHKTDEMHTALME-ACMDGHVEVARLL 453



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 44/155 (28%), Positives = 74/155 (47%), Gaps = 3/155 (1%)

Query: 89   LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
            L+ AA A +VG++  L+  G  +E   +++R   T L +AC  G  + VV L      + 
Sbjct: 869  LILAATAGHVGVVEILLDNGADIEA--QSERTKDTPLSLACSGGRQE-VVELLLARGANK 925

Query: 149  NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
              ++    T L  AA  G+  I   LLN    ++    +  G + LM AAM G T  ++ 
Sbjct: 926  EHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKL 985

Query: 209  LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
            L+  G+D++A+      +    A + GR + V L+
Sbjct: 986  LLDMGSDINAQIETNRNTALTLACFQGRTEVVSLL 1020



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 52/166 (31%), Positives = 71/166 (42%), Gaps = 6/166 (3%)

Query: 79  VPESVPETATLLRAAC-ANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTV 137
           V E   E  +LL  AC A    L + L+    +VE+     +   T L+ A   G V  +
Sbjct: 260 VNEHTEEGESLLCLACSAGYYELAQVLLAMHANVED--RGIKGDITPLMAAANGGHVK-I 316

Query: 138 VALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKA 197
           V L      DVN Q S GNTAL  A   G+  +   LL    G  +E  N  G T LM+A
Sbjct: 317 VKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLE--SGASIEDHNENGHTPLMEA 374

Query: 198 AMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
              G  +  R L+  GA ++        S    A Y G ++ VR +
Sbjct: 375 GSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFL 420



 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 45/131 (34%), Positives = 67/131 (51%), Gaps = 10/131 (7%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L  AAC  +V L   L+ RG S+EE  +    G T L+ A   G  + +VAL      ++
Sbjct: 471 LTLAACGGHVELAALLIERGASLEEVND---EGYTPLMEAAREGH-EEMVALLLGQGANI 526

Query: 149 NWQDSEGN-TALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIR 207
           N Q  E   TAL  A   G   + ++L+    G D+E   +   T LM+AA +G  + ++
Sbjct: 527 NAQTEETQETALTLACCGGFLEVADFLIK--AGADIELGCS---TPLMEAAQEGHLELVK 581

Query: 208 ALMLAGADVHA 218
            L+ AGA+VHA
Sbjct: 582 YLLAAGANVHA 592



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 34/101 (33%), Positives = 50/101 (49%), Gaps = 3/101 (2%)

Query: 144 PHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGR 202
           P +D++ Q +S  +TAL  A   GH  +   LL    G  +E R+  GFT L+ AA  G 
Sbjct: 820 PAIDIDAQTESNHDTALTLACAGGHEELVQTLLER--GASIEHRDKKGFTPLILAATAGH 877

Query: 203 TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
              +  L+  GAD+ A+  R   +P   A   GR + V L+
Sbjct: 878 VGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELL 918



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 51/197 (25%), Positives = 81/197 (41%), Gaps = 17/197 (8%)

Query: 54  SDDSFYPFEDEEEHGVESAESVPEGV-------PESVPETATLLRAACANNVGLLRTLVR 106
           +D+ + P  +    G E   ++  G         E   ETA  L A C   + +   L++
Sbjct: 497 NDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTL-ACCGGFLEVADFLIK 555

Query: 107 RGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAG 166
            G  +E    T       L+ A   G ++ V  L      +V+   + G+TAL  A + G
Sbjct: 556 AGADIELGCSTP------LMEAAQEGHLELVKYLLAAG-ANVHATTATGDTALTYACENG 608

Query: 167 HAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMS 226
           H  + + LL    G DLE  +  G T LMKAA  G    ++ L+  GA+V+        +
Sbjct: 609 HTDVADVLLQ--AGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHT 666

Query: 227 PQEWATYTGRVDAVRLM 243
               A   G +  V L+
Sbjct: 667 VLSLACAGGHLAVVELL 683



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 40/162 (24%), Positives = 66/162 (40%), Gaps = 34/162 (20%)

Query: 89  LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
           L+ A  A +V + R L+  G  +     ++    + L +ACY G ++ V  L E    D 
Sbjct: 371 LMEAGSAGHVEVARLLLENGAGINT--HSNEFKESALTLACYKGHLEMVRFLLEAG-ADQ 427

Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFP----------------------------- 179
             +  E +TAL+ A   GH  +   LL+                                
Sbjct: 428 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLI 487

Query: 180 --GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 219
             G  LE  N  G+T LM+AA +G  + +  L+  GA+++A+
Sbjct: 488 ERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQ 529



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 3/97 (3%)

Query: 81  ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 140
           ES      L++AA A +V  ++ L+ +G +V     T  N  T L +AC  G +  VV L
Sbjct: 626 ESEGGRTPLMKAARAGHVCTVQFLISKGANVNRT--TANNDHTVLSLACAGGHL-AVVEL 682

Query: 141 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNY 177
                 D   +  +G+T LI AA+ GH  +  YLL+Y
Sbjct: 683 LLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDY 719



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 5/138 (3%)

Query: 82   SVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALA 141
            +V +   L  AA    V +++ L+  G  +  ++   + G + L++A  +G    V  L 
Sbjct: 929  NVSDYTPLSLAASGGYVNIIKILLNAGAEIN-SRTGSKLGISPLMLAAMNGHTAAVKLLL 987

Query: 142  ECPHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 200
            +    D+N Q ++  NTAL  A   G   + + LL+     ++E R   G T LM+AA  
Sbjct: 988  DMGS-DINAQIETNRNTALTLACFQGRTEVVSLLLDR--KANVEHRAKTGLTPLMEAASG 1044

Query: 201  GRTDCIRALMLAGADVHA 218
            G  +  R L+  GADV+A
Sbjct: 1045 GYAEVGRVLLDKGADVNA 1062



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 42/161 (26%), Positives = 70/161 (43%), Gaps = 13/161 (8%)

Query: 88   TLLRAACANN-VGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAEC-PH 145
            T L  AC+     ++  L+ RG + E    +D    T L +A   G+V+ +  L      
Sbjct: 901  TPLSLACSGGRQEVVELLLARGANKEHRNVSDY---TPLSLAASGGYVNIIKILLNAGAE 957

Query: 146  VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE---RRNAFGFTALMKAAMQGR 202
            ++       G + L+ AA  GH      LL+    ++ +    RN    TAL  A  QGR
Sbjct: 958  INSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRN----TALTLACFQGR 1013

Query: 203  TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
            T+ +  L+   A+V  R  + G++P   A   G  +  R++
Sbjct: 1014 TEVVSLLLDRKANVEHR-AKTGLTPLMEAASGGYAEVGRVL 1053



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 9/104 (8%)

Query: 79   VPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVV 138
            VP S     T+  AA   +      L+ RG  ++     ++ G T L +A   G +D V 
Sbjct: 1065 VPSSRDTALTI--AADKGHYKFCELLIGRGAHIDVR---NKKGNTPLWLAANGGHLDVVQ 1119

Query: 139  ALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYL---LNYFP 179
             L +    DV+  D+   T L+ A + GH  +  YL   +N FP
Sbjct: 1120 LLVQAG-ADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFP 1162


>gi|89363047 death-associated protein kinase 1 [Homo sapiens]
          Length = 1430

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 51/160 (31%), Positives = 80/160 (50%), Gaps = 11/160 (6%)

Query: 86  TATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAE--C 143
           T  LL AA   N+ +L+ L++RG  ++     D+ G   +  A  HG VDT+  L+E  C
Sbjct: 380 TPPLLIAAGCGNIQILQLLIKRGSRIDVQ---DKGGSNAVYWAARHGHVDTLKFLSENKC 436

Query: 144 PHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRT 203
           P +DV  +D  G  AL  AA+ GHA +   L ++    +++ +     T L  AA  G  
Sbjct: 437 P-LDV--KDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEE--ETPLHCAAWHGYY 491

Query: 204 DCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
              +AL  AG +V+ ++ R G +P   A+  G  D V  +
Sbjct: 492 SVAKALCEAGCNVNIKN-REGETPLLTASARGYHDIVECL 530



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 42/142 (29%), Positives = 63/142 (44%), Gaps = 7/142 (4%)

Query: 118 DRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNY 177
           D+   T L  A +HG+     AL E    +VN ++ EG T L+TA+  G+  I   L  +
Sbjct: 475 DKEEETPLHCAAWHGYYSVAKALCEAG-CNVNIKNREGETPLLTASARGYHDIVECLAEH 533

Query: 178 FPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRV 237
             G DL   +  G  AL  A  + + + I+ L+  G  V  +D R G +P   A   G +
Sbjct: 534 --GADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQD-RHGNTPLHVACKDGNM 590

Query: 238 DAVRLMQRLLERPCPEQFWEKY 259
               ++  L E  C      KY
Sbjct: 591 P---IVVALCEANCNLDISNKY 609



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 6/94 (6%)

Query: 100 LLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTAL 159
           +++TL+ +G  V+     DR+G T L VAC  G +  VVAL E  + +++  +  G T L
Sbjct: 559 VIKTLLSQGCFVDYQ---DRHGNTPLHVACKDGNMPIVVALCEA-NCNLDISNKYGRTPL 614

Query: 160 ITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTA 193
             AA  G   +  YL     G  +E     G TA
Sbjct: 615 HLAANNGILDVVRYLC--LMGASVEALTTDGKTA 646


>gi|17864094 feminization 1 homolog a [Homo sapiens]
          Length = 617

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 46/160 (28%), Positives = 76/160 (47%), Gaps = 8/160 (5%)

Query: 81  ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 140
           E++     L  A+ A ++ ++++L+  G SV     T+    T L  AC+ G ++ V  L
Sbjct: 79  ETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNS---TPLRAACFDGHLEIVKYL 135

Query: 141 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 200
            E    D+   +  G+T L+ +   GH  I  YLL    G D+ R++  G TAL   A  
Sbjct: 136 VE-HKADLEVSNRHGHTCLMISCYKGHKEIAQYLLE--KGADVNRKSVKGNTALHDCAES 192

Query: 201 GRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV 240
           G  D ++ L++  A +       GM+P   A+ TG  + V
Sbjct: 193 GSLDIMKMLLMYCAKM--EKDGYGMTPLLSASVTGHTNIV 230



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 45/180 (25%), Positives = 77/180 (42%), Gaps = 10/180 (5%)

Query: 70  ESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRR-GVSVEEAQETDRNGRT----- 123
           +S E V   + E       LL AA   ++ ++  L+ +   S+E     + +G T     
Sbjct: 26  KSKEEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAP 85

Query: 124 GLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDL 183
            L  A   G +  V +L       VN      +T L  A   GH  I  YL+ +    DL
Sbjct: 86  PLWAASAAGHLKVVQSLLN-HGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEH--KADL 142

Query: 184 ERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
           E  N  G T LM +  +G  +  + L+  GADV+ +  +   +  + A  +G +D ++++
Sbjct: 143 EVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAE-SGSLDIMKML 201


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,412,079
Number of Sequences: 37866
Number of extensions: 1316552
Number of successful extensions: 15053
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 210
Number of HSP's successfully gapped in prelim test: 497
Number of HSP's that attempted gapping in prelim test: 12123
Number of HSP's gapped (non-prelim): 2884
length of query: 494
length of database: 18,247,518
effective HSP length: 106
effective length of query: 388
effective length of database: 14,233,722
effective search space: 5522684136
effective search space used: 5522684136
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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