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Search of human proteins with 239742483
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239742483 PREDICTED: ankyrin repeat domain 33B [Homo
sapiens]
(494 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169167742 PREDICTED: ankyrin repeat domain 33B [Homo sapiens] 1001 0.0
gi|239742483 PREDICTED: ankyrin repeat domain 33B [Homo sapiens] 1001 0.0
gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens] 924 0.0
gi|194097375 ankyrin repeat domain 33 isoform 2 [Homo sapiens] 229 4e-60
gi|194097377 ankyrin repeat domain 33 isoform 1 [Homo sapiens] 213 3e-55
gi|239755481 PREDICTED: similar to Putative uncharacterized prot... 96 1e-19
gi|239744358 PREDICTED: hypothetical protein XP_002343105 [Homo ... 96 1e-19
gi|62988328 ankyrin repeat domain 50 [Homo sapiens] 75 1e-13
gi|24308163 fem-1 homolog a [Homo sapiens] 71 2e-12
gi|96975023 ankyrin repeat and death domain containing 1A [Homo ... 71 3e-12
gi|46519154 ankyrin repeat and KH domain containing 1 isoform 3 ... 69 1e-11
gi|46519151 ankyrin repeat and KH domain containing 1 isoform 2 ... 69 1e-11
gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 ... 69 1e-11
gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens] 69 1e-11
gi|169208819 PREDICTED: similar to kinase D-interacting substrat... 66 6e-11
gi|169208593 PREDICTED: similar to kinase D-interacting substrat... 66 6e-11
gi|55741641 kinase D-interacting substrate of 220 kDa [Homo sapi... 66 6e-11
gi|70995267 ankyrin repeat domain 29 [Homo sapiens] 65 1e-10
gi|169208169 PREDICTED: similar to kinase D-interacting substrat... 64 4e-10
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 63 5e-10
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 63 5e-10
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 63 5e-10
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 63 5e-10
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 63 5e-10
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 63 5e-10
gi|110431370 espin [Homo sapiens] 62 1e-09
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap... 60 5e-09
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap... 60 5e-09
gi|89363047 death-associated protein kinase 1 [Homo sapiens] 59 1e-08
gi|17864094 feminization 1 homolog a [Homo sapiens] 58 2e-08
>gi|169167742 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
Length = 494
Score = 1001 bits (2588), Expect = 0.0
Identities = 494/494 (100%), Positives = 494/494 (100%)
Query: 1 MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYP 60
MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYP
Sbjct: 1 MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYP 60
Query: 61 FEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRN 120
FEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRN
Sbjct: 61 FEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRN 120
Query: 121 GRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPG 180
GRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPG
Sbjct: 121 GRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPG 180
Query: 181 LDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV 240
LDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV
Sbjct: 181 LDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV 240
Query: 241 RLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPE 300
RLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPE
Sbjct: 241 RLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPE 300
Query: 301 DGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEED 360
DGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEED
Sbjct: 301 DGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEED 360
Query: 361 EVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPG 420
EVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPG
Sbjct: 361 EVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPG 420
Query: 421 VVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAE 480
VVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAE
Sbjct: 421 VVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAE 480
Query: 481 AQKERRTAPWKKRT 494
AQKERRTAPWKKRT
Sbjct: 481 AQKERRTAPWKKRT 494
>gi|239742483 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
Length = 494
Score = 1001 bits (2588), Expect = 0.0
Identities = 494/494 (100%), Positives = 494/494 (100%)
Query: 1 MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYP 60
MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYP
Sbjct: 1 MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYP 60
Query: 61 FEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRN 120
FEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRN
Sbjct: 61 FEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRN 120
Query: 121 GRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPG 180
GRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPG
Sbjct: 121 GRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPG 180
Query: 181 LDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV 240
LDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV
Sbjct: 181 LDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV 240
Query: 241 RLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPE 300
RLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPE
Sbjct: 241 RLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPE 300
Query: 301 DGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEED 360
DGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEED
Sbjct: 301 DGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEED 360
Query: 361 EVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPG 420
EVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPG
Sbjct: 361 EVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPG 420
Query: 421 VVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAE 480
VVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAE
Sbjct: 421 VVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAE 480
Query: 481 AQKERRTAPWKKRT 494
AQKERRTAPWKKRT
Sbjct: 481 AQKERRTAPWKKRT 494
>gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
Length = 1006
Score = 924 bits (2389), Expect = 0.0
Identities = 466/490 (95%), Positives = 469/490 (95%), Gaps = 3/490 (0%)
Query: 8 GPEGGGARCMTPPP-PSPPRGAQ-VEEDPADYEEFEDF-SSLPDTRSIASDDSFYPFEDE 64
G GA+ P PSPP GAQ VEEDPADYEEFED S ++ SDDSFYPFEDE
Sbjct: 517 GRRAAGAQLHDPTTQPSPPTGAQQVEEDPADYEEFEDILESARHPQASHSDDSFYPFEDE 576
Query: 65 EEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTG 124
EEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTG
Sbjct: 577 EEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTG 636
Query: 125 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 184
LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE
Sbjct: 637 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 696
Query: 185 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQ 244
RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQ
Sbjct: 697 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQ 756
Query: 245 RLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGV 304
RLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGV
Sbjct: 757 RLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGV 816
Query: 305 LDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGG 364
LDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGG
Sbjct: 817 LDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGG 876
Query: 365 AGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVP 424
AGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVP
Sbjct: 877 AGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVP 936
Query: 425 RVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKE 484
RVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKE
Sbjct: 937 RVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKE 996
Query: 485 RRTAPWKKRT 494
RRTAPWKKRT
Sbjct: 997 RRTAPWKKRT 1006
Score = 33.5 bits (75), Expect = 0.46
Identities = 41/150 (27%), Positives = 56/150 (37%), Gaps = 27/150 (18%)
Query: 327 VCPES-PPSVGKRRLAVQEILAARA---ARGPQAQEEDEVGGAGQRGRTGQEDADSREGS 382
V PE+ P G+ L E RGP A + G G+ G+ E R
Sbjct: 370 VSPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGRLQGKGREGKAPGEGVSPRPAP 429
Query: 383 PRAGLPPALGSRGPAAPAP-------RKASLLPLQRLRRRS---------VRPGVV---- 422
PR G PP SR P A ++ L+P+ R+ R G +
Sbjct: 430 PRLGKPPR--SRPPQGLAQPPETFFFERSRLVPVSAELERAGHGFSGDAEARSGDLGARP 487
Query: 423 VPRVRVSKAPAPTFQPERPARKGST-KDSG 451
R + APAP Q + AR G+ +D G
Sbjct: 488 ASRSSLPSAPAPPAQQPQAARHGAAGRDQG 517
>gi|194097375 ankyrin repeat domain 33 isoform 2 [Homo sapiens]
Length = 452
Score = 229 bits (584), Expect = 4e-60
Identities = 161/430 (37%), Positives = 215/430 (50%), Gaps = 51/430 (11%)
Query: 60 PFEDEEEHGVESAE-SVPEGVPESVPETAT-------LLRAACANNVGLLRTLVRRGVSV 111
P +EEE + + E +P ET T L A N+ L+ ++ GVS
Sbjct: 62 PCLEEEELALHRRRLDMSEALPCPGKETPTPGCRLGALYWACVHNDPTQLQAILDGGVSP 121
Query: 112 EEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIIT 171
EEA + D NGRTGL+VACYHGF V L+ CP +DVN QD G+TAL+ AAQAGH +
Sbjct: 122 EEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLV 181
Query: 172 NYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWA 231
+ LLNY+ GLDLERR+ G TALMKAAM+ R AD+ A DP RG + EWA
Sbjct: 182 SLLLNYYVGLDLERRDQRGLTALMKAAMRNRC----------ADLTAVDPVRGKTALEWA 231
Query: 232 TYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVL 291
T D V +++LL RP EQ + Y+PE P + L + + + L
Sbjct: 232 VLTDSFDTVWRIRQLLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATL 291
Query: 292 TPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAA 351
+ P++GGVLDH+V TTSL SP V C T+CP+ PPS+G R +V E+L
Sbjct: 292 SLPFAPSPQEGGVLDHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELL----- 346
Query: 352 RGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQR 411
G A Q S + SP +P +P+ LQ
Sbjct: 347 -----------GTAPPPPLVPQSPPGSPQRSPWVFVP---------YQSPQGILSKCLQW 386
Query: 412 LRRR-SVRPGVVVPRVRVSKAPAPTFQPERPARKGSTKDSGH--LQIPKWRYKEAKEEKR 468
L+ R S P VP++ +SKA + + Q + SGH L +P WRY+E + EKR
Sbjct: 387 LQPRDSTSPRPQVPKILLSKASSSSHQCQP-----KPSPSGHQSLALPLWRYQELRIEKR 441
Query: 469 KAEEAEKKRQ 478
K EE + Q
Sbjct: 442 KQEEEARMAQ 451
>gi|194097377 ankyrin repeat domain 33 isoform 1 [Homo sapiens]
Length = 272
Score = 213 bits (542), Expect = 3e-55
Identities = 117/271 (43%), Positives = 156/271 (57%), Gaps = 14/271 (5%)
Query: 126 IVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLER 185
+VACYHGF V L+ CP +DVN QD G+TAL+ AAQAGH + + LLNY+ GLDLER
Sbjct: 1 MVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLER 60
Query: 186 RNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQR 245
R+ G TALMKAAM+ R +C+ L++AGAD+ A DP RG + EWA T D V +++
Sbjct: 61 RDQRGLTALMKAAMRNRCECVATLLMAGADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQ 120
Query: 246 LLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGVL 305
LL RP EQ + Y+PE P + L + + + L+ P++GGVL
Sbjct: 121 LLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVL 180
Query: 306 DHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARG------------ 353
DH+V TTSL SP V C T+CP+ PPS+G R +V E+L A+
Sbjct: 181 DHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLVPAEAQSFRTPKSGPSSLA 240
Query: 354 -PQAQE-EDEVGGAGQRGRTGQEDADSREGS 382
P AQ+ E+E GG GQ G ED + G+
Sbjct: 241 IPGAQDREEETGGGGQNGTEVGEDGIGQAGN 271
>gi|239755481 PREDICTED: similar to Putative uncharacterized
protein ENSP00000334305 [Homo sapiens]
Length = 771
Score = 95.5 bits (236), Expect = 1e-19
Identities = 44/61 (72%), Positives = 51/61 (83%)
Query: 17 MTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYPFEDEEEHGVESAESVP 76
MTPPPPSP G QV+ED ADY+EF+DFSSLPDT +IA D SFYPF++EEEHGV+ ESV
Sbjct: 1 MTPPPPSPLLGTQVKEDRADYKEFQDFSSLPDTHNIAWDHSFYPFQEEEEHGVKGVESVL 60
Query: 77 E 77
E
Sbjct: 61 E 61
Score = 62.8 bits (151), Expect = 7e-10
Identities = 37/68 (54%), Positives = 41/68 (60%), Gaps = 6/68 (8%)
Query: 211 LAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAA 270
LAGA VHAR P G + + VRL QRLLERPC E +KY+ ELPP E A
Sbjct: 93 LAGAVVHARAPAVGCRQRSGHLH------VRLKQRLLERPCQEPLGKKYQLELPPLYERA 146
Query: 271 RKPAGSKN 278
RKP GSKN
Sbjct: 147 RKPEGSKN 154
Score = 62.4 bits (150), Expect = 9e-10
Identities = 30/46 (65%), Positives = 35/46 (76%), Gaps = 1/46 (2%)
Query: 449 DSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRTAPWKKRT 494
D+ HL+ PKW YK EEK +AEEAEKKRQA+ Q E+ APWKKRT
Sbjct: 206 DTRHLRTPKWPYKVVTEEKPEAEEAEKKRQAKVQ-EKHPAPWKKRT 250
>gi|239744358 PREDICTED: hypothetical protein XP_002343105 [Homo
sapiens]
Length = 767
Score = 95.5 bits (236), Expect = 1e-19
Identities = 44/61 (72%), Positives = 51/61 (83%)
Query: 17 MTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYPFEDEEEHGVESAESVP 76
MTPPPPSP G QV+ED ADY+EF+DFSSLPDT +IA D SFYPF++EEEHGV+ ESV
Sbjct: 1 MTPPPPSPLLGTQVKEDRADYKEFQDFSSLPDTHNIAWDHSFYPFQEEEEHGVKGVESVL 60
Query: 77 E 77
E
Sbjct: 61 E 61
Score = 63.9 bits (154), Expect = 3e-10
Identities = 31/46 (67%), Positives = 36/46 (78%), Gaps = 1/46 (2%)
Query: 449 DSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRTAPWKKRT 494
D+ HL+ PKW YK A EEK +AEEAEKKRQA+ Q E+R PWKKRT
Sbjct: 202 DTRHLRTPKWPYKVATEEKPEAEEAEKKRQAKVQ-EKRLPPWKKRT 246
Score = 62.4 bits (150), Expect = 9e-10
Identities = 36/68 (52%), Positives = 41/68 (60%), Gaps = 6/68 (8%)
Query: 211 LAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAA 270
LAGA +HAR P G + + VRL QRLLERPC E +KY+ ELPP E A
Sbjct: 93 LAGAVIHARAPAVGCRQRSGHLH------VRLKQRLLERPCQEPLGKKYQLELPPLYERA 146
Query: 271 RKPAGSKN 278
RKP GSKN
Sbjct: 147 RKPEGSKN 154
>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
Length = 1429
Score = 75.1 bits (183), Expect = 1e-13
Identities = 56/170 (32%), Positives = 82/170 (48%), Gaps = 9/170 (5%)
Query: 66 EHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGL 125
+HG E +G + A L A + ++ L+ RG V+ D++G T L
Sbjct: 698 DHGAEVNHEDVDG--RTALSVAALCVPASKGHASVVSLLIDRGAEVDHC---DKDGMTPL 752
Query: 126 IVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLER 185
+VA Y G VD V L E DV+ D+ G T L+ AA GHA + N LL F G ++
Sbjct: 753 LVAAYEGHVDVVDLLLE-GGADVDHTDNNGRTPLLAAASMGHASVVNTLL--FWGAAVDS 809
Query: 186 RNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTG 235
++ G T L A+ QG + +R L+ G D + RD G +P A + G
Sbjct: 810 IDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDD-AGWTPLHMAAFEG 858
Score = 68.9 bits (167), Expect = 1e-11
Identities = 55/158 (34%), Positives = 79/158 (50%), Gaps = 8/158 (5%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L AA + ++ L+ GV V+ A D + RT L A + G D V+ L + +V
Sbjct: 615 LRSAAWGGHTEVVSALLYAGVKVDCA---DADSRTALRAAAWGGHEDIVLNLLQ-HGAEV 670
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGL---DLERRNAFGFTALMKAAMQGRTDC 205
N D+EG TALI AA GH I +LL++ + D++ R A AL A +G
Sbjct: 671 NKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASV 730
Query: 206 IRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
+ L+ GA+V D + GM+P A Y G VD V L+
Sbjct: 731 VSLLIDRGAEVDHCD-KDGMTPLLVAAYEGHVDVVDLL 767
Score = 67.0 bits (162), Expect = 4e-11
Identities = 45/120 (37%), Positives = 63/120 (52%), Gaps = 6/120 (5%)
Query: 101 LRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALI 160
+RTL+ G SV + D NGRT L A Y G +D VV L D+ +D+ G+T L
Sbjct: 528 IRTLLDNGASVNQC---DSNGRTLLANAAYSGSLD-VVNLLVSRGADLEIEDAHGHTPLT 583
Query: 161 TAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 220
AA+ GH + N L+ G ++ + G+TAL AA G T+ + AL+ AG V D
Sbjct: 584 LAARQGHTKVVNCLIGC--GANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCAD 641
Score = 65.5 bits (158), Expect = 1e-10
Identities = 48/158 (30%), Positives = 77/158 (48%), Gaps = 7/158 (4%)
Query: 88 TLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVD 147
TL A N + + + G +VE + D GRT L V+C+ G ++ V L H D
Sbjct: 949 TLYILALENQLTMAEYFLENGANVEAS---DAEGRTALHVSCWQGHMEMVQVLIAY-HAD 1004
Query: 148 VNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIR 207
VN D+E +AL +AA GH + L+ + G ++ G TAL AA +G D ++
Sbjct: 1005 VNAADNEKRSALQSAAWQGHVKVVQLLIEH--GAVVDHTCNQGATALCIAAQEGHIDVVQ 1062
Query: 208 ALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQR 245
L+ GAD + D + G + A G ++L+++
Sbjct: 1063 VLLEHGADPNHAD-QFGRTAMRVAAKNGHSQIIKLLEK 1099
Score = 50.4 bits (119), Expect = 4e-06
Identities = 39/124 (31%), Positives = 59/124 (47%), Gaps = 4/124 (3%)
Query: 120 NGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFP 179
+GR L VA G D +V L DVN +D++G L A + Y L
Sbjct: 912 DGRNALRVAALEGHRD-IVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLEN-- 968
Query: 180 GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDA 239
G ++E +A G TAL + QG + ++ L+ ADV+A D + + Q A + G V
Sbjct: 969 GANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQS-AAWQGHVKV 1027
Query: 240 VRLM 243
V+L+
Sbjct: 1028 VQLL 1031
Score = 50.1 bits (118), Expect = 5e-06
Identities = 44/141 (31%), Positives = 65/141 (46%), Gaps = 9/141 (6%)
Query: 100 LLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTAL 159
+L+ LV+ G V + RT IV D++ L + VN DS G T L
Sbjct: 496 VLQLLVKAGAHVNSEDD-----RTSCIVRQALEREDSIRTLLD-NGASVNQCDSNGRTLL 549
Query: 160 ITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 219
AA +G + N L++ G DLE +A G T L AA QG T + L+ GA+++
Sbjct: 550 ANAAYSGSLDVVNLLVSR--GADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHT 607
Query: 220 DPRRGMSPQEWATYTGRVDAV 240
D + G + A + G + V
Sbjct: 608 D-QDGWTALRSAAWGGHTEVV 627
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 4/91 (4%)
Query: 87 ATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHV 146
+ L AA +V +++ L+ G V+ T G T L +A G +D V L E
Sbjct: 1014 SALQSAAWQGHVKVVQLLIEHGAVVDH---TCNQGATALCIAAQEGHIDVVQVLLE-HGA 1069
Query: 147 DVNWQDSEGNTALITAAQAGHAIITNYLLNY 177
D N D G TA+ AA+ GH+ I L Y
Sbjct: 1070 DPNHADQFGRTAMRVAAKNGHSQIIKLLEKY 1100
>gi|24308163 fem-1 homolog a [Homo sapiens]
Length = 669
Score = 71.2 bits (173), Expect = 2e-12
Identities = 60/202 (29%), Positives = 93/202 (46%), Gaps = 15/202 (7%)
Query: 81 ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 140
E++ L A+ A ++ ++R+L+RRG SV T R T L AC+ G ++ V L
Sbjct: 79 ETIEGAPPLWAASAAGHLDVVRSLLRRGASVNR---TTRTNSTPLRAACFDGHLEVVRYL 135
Query: 141 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 200
D+ + G+T L+ + GH I YLL G + RR+A G TAL A
Sbjct: 136 VGEHQADLEVANRHGHTCLMISCYKGHREIARYLLE--QGAQVNRRSAKGNTALHDCAES 193
Query: 201 GRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQF-WEKY 259
G + ++ +L G GM+P A+ TG + V + + E+P EQ +
Sbjct: 194 GSLEILQ--LLLGCKARMERDGYGMTPLLAASVTGHTNIVEYL--IQEQPGQEQVAGGEA 249
Query: 260 RPELPPPPEAARKPAGSKNCLQ 281
+P LP P+ S+ C Q
Sbjct: 250 QPGLP-----QEDPSTSQGCAQ 266
Score = 39.3 bits (90), Expect = 0.008
Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 18/101 (17%)
Query: 155 GNTALITAAQAGHAIITNYLLN------------YFPGLDLERRNAFGFTALMKAAMQGR 202
G T L+ AA+ GH + YL++ +F G +E G L A+ G
Sbjct: 41 GGTPLLIAARYGHLDVVEYLVDRCGASVEAGGSVHFDGETIE-----GAPPLWAASAAGH 95
Query: 203 TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
D +R+L+ GA V+ R R +P A + G ++ VR +
Sbjct: 96 LDVVRSLLRRGASVN-RTTRTNSTPLRAACFDGHLEVVRYL 135
>gi|96975023 ankyrin repeat and death domain containing 1A [Homo
sapiens]
Length = 522
Score = 70.9 bits (172), Expect = 3e-12
Identities = 53/158 (33%), Positives = 77/158 (48%), Gaps = 8/158 (5%)
Query: 88 TLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL--AECPH 145
TLL A + + + D+ GRT A HG +D + L + C H
Sbjct: 126 TLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDH 185
Query: 146 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDC 205
N +D EGNTAL AA GH + L++ GLDLE +NA G TAL AA DC
Sbjct: 186 ---NVKDKEGNTALHLAAGRGHMAVLQRLVDI--GLDLEEQNAEGLTALHSAAGGSHPDC 240
Query: 206 IRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
++ L+ AG+ V+A ++ +S +A +G D R++
Sbjct: 241 VQLLLRAGSTVNAL-TQKNLSCLHYAALSGSEDVSRVL 277
Score = 40.4 bits (93), Expect = 0.004
Identities = 30/128 (23%), Positives = 61/128 (47%), Gaps = 5/128 (3%)
Query: 121 GRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPG 180
G L+++ + G + + L ++ + +G T L AAQ GH + +++
Sbjct: 91 GMNALLLSAWFGHLRILQILVNSG-AKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLED 149
Query: 181 LDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV 240
+ L+ + G TA +AA G+ D + L+ +G D + +D + G + A G +
Sbjct: 150 VALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKD-KEGNTALHLAAGRGH---M 205
Query: 241 RLMQRLLE 248
++QRL++
Sbjct: 206 AVLQRLVD 213
Score = 36.6 bits (83), Expect = 0.054
Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 9/111 (8%)
Query: 146 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLD--------LERRNAFGFTALMKA 197
V+ ++ G AL AA AGH LL + +D E R FG AL+ +
Sbjct: 39 VNTRARNHVGRVALHWAAGAGHEQAVRLLLEHEAAVDEEDAVGALTEARLCFGMNALLLS 98
Query: 198 AMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLE 248
A G ++ L+ +GA +H + + G++ A G V + + LE
Sbjct: 99 AWFGHLRILQILVNSGAKIHC-ESKDGLTLLHCAAQKGHVPVLAFIMEDLE 148
Score = 32.7 bits (73), Expect = 0.78
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 96 NNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEG 155
N L+R L+ S + D +T L +A H + D + + VD+N +D +G
Sbjct: 302 NFPALVRLLIN---SDSDVNAVDNRQQTPLHLAAEHAWQD-IADMLLIAGVDLNLRDKQG 357
Query: 156 NTALITAAQAGHAIITNYLL 175
TAL A ++ H + + ++
Sbjct: 358 KTALAVAVRSNHVSLVDMII 377
>gi|46519154 ankyrin repeat and KH domain containing 1 isoform 3
[Homo sapiens]
Length = 627
Score = 68.9 bits (167), Expect = 1e-11
Identities = 63/197 (31%), Positives = 87/197 (44%), Gaps = 11/197 (5%)
Query: 48 DTRSIASDDSFYPFEDEEEHGVESAESVPEGVPESVPETATLLRAAC-ANNVGLLRTLVR 106
DTRS+A S D + + V V E E +LL AC A L + L+
Sbjct: 205 DTRSLAEACS-----DGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 259
Query: 107 RGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAG 166
+VE+ ++ T L+ A G++D +V L DVN Q + GNTAL A G
Sbjct: 260 MHANVED--RGNKGDITPLMAASSGGYLD-IVKLLLLHDADVNSQSATGNTALTYACAGG 316
Query: 167 HAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMS 226
I LLN G ++E N G T LM+AA G + R L+ GA ++ S
Sbjct: 317 FVDIVKVLLN--EGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKES 374
Query: 227 PQEWATYTGRVDAVRLM 243
A Y G +D VR +
Sbjct: 375 ALTLACYKGHLDMVRFL 391
Score = 60.1 bits (144), Expect = 5e-09
Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 6/155 (3%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ A+ + +++ L+ V T G T L AC GFVD V L ++
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSAT---GNTALTYACAGGFVDIVKVLLN-EGANI 331
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
+ G+T L+ AA AGH + LL++ G++ N F +AL A +G D +R
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHS-NEFKESALTLACYKGHLDMVRF 390
Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
L+ AGAD + + E A G V+ RL+
Sbjct: 391 LLEAGADQEHKTDEMHTALME-ACMDGHVEVARLL 424
Score = 54.3 bits (129), Expect = 2e-07
Identities = 42/131 (32%), Positives = 68/131 (51%), Gaps = 10/131 (7%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L AAC +V L L+ RG ++EE + G T L+ A G + +VAL ++
Sbjct: 442 LTLAACGGHVELAALLIERGANLEEVND---EGYTPLMEAAREGH-EEMVALLLAQGANI 497
Query: 149 NWQDSEGN-TALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIR 207
N Q E TAL A G + + ++L+ G D+E + T LM+A+ +G + ++
Sbjct: 498 NAQTEETQETALTLACCGGFSEVADFLIK--AGADIELGCS---TPLMEASQEGHLELVK 552
Query: 208 ALMLAGADVHA 218
L+ +GA+VHA
Sbjct: 553 YLLASGANVHA 563
Score = 50.1 bits (118), Expect = 5e-06
Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 34/162 (20%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ AA A +V + R L+ G + ++ + L +ACY G +D V L E D
Sbjct: 342 LMEAASAGHVEVARVLLDHGAGINT--HSNEFKESALTLACYKGHLDMVRFLLEAG-ADQ 398
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFP----------------------------- 179
+ E +TAL+ A GH + LL+
Sbjct: 399 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLI 458
Query: 180 --GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 219
G +LE N G+T LM+AA +G + + L+ GA+++A+
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500
>gi|46519151 ankyrin repeat and KH domain containing 1 isoform 2
[Homo sapiens]
Length = 616
Score = 68.9 bits (167), Expect = 1e-11
Identities = 63/197 (31%), Positives = 87/197 (44%), Gaps = 11/197 (5%)
Query: 48 DTRSIASDDSFYPFEDEEEHGVESAESVPEGVPESVPETATLLRAAC-ANNVGLLRTLVR 106
DTRS+A S D + + V V E E +LL AC A L + L+
Sbjct: 194 DTRSLAEACS-----DGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 248
Query: 107 RGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAG 166
+VE+ ++ T L+ A G++D +V L DVN Q + GNTAL A G
Sbjct: 249 MHANVED--RGNKGDITPLMAASSGGYLD-IVKLLLLHDADVNSQSATGNTALTYACAGG 305
Query: 167 HAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMS 226
I LLN G ++E N G T LM+AA G + R L+ GA ++ S
Sbjct: 306 FVDIVKVLLN--EGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKES 363
Query: 227 PQEWATYTGRVDAVRLM 243
A Y G +D VR +
Sbjct: 364 ALTLACYKGHLDMVRFL 380
Score = 60.1 bits (144), Expect = 5e-09
Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 6/155 (3%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ A+ + +++ L+ V T G T L AC GFVD V L ++
Sbjct: 265 LMAASSGGYLDIVKLLLLHDADVNSQSAT---GNTALTYACAGGFVDIVKVLLN-EGANI 320
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
+ G+T L+ AA AGH + LL++ G++ N F +AL A +G D +R
Sbjct: 321 EDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHS-NEFKESALTLACYKGHLDMVRF 379
Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
L+ AGAD + + E A G V+ RL+
Sbjct: 380 LLEAGADQEHKTDEMHTALME-ACMDGHVEVARLL 413
Score = 54.3 bits (129), Expect = 2e-07
Identities = 42/131 (32%), Positives = 68/131 (51%), Gaps = 10/131 (7%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L AAC +V L L+ RG ++EE + G T L+ A G + +VAL ++
Sbjct: 431 LTLAACGGHVELAALLIERGANLEEVND---EGYTPLMEAAREGH-EEMVALLLAQGANI 486
Query: 149 NWQDSEGN-TALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIR 207
N Q E TAL A G + + ++L+ G D+E + T LM+A+ +G + ++
Sbjct: 487 NAQTEETQETALTLACCGGFSEVADFLIK--AGADIELGCS---TPLMEASQEGHLELVK 541
Query: 208 ALMLAGADVHA 218
L+ +GA+VHA
Sbjct: 542 YLLASGANVHA 552
Score = 50.1 bits (118), Expect = 5e-06
Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 34/162 (20%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ AA A +V + R L+ G + ++ + L +ACY G +D V L E D
Sbjct: 331 LMEAASAGHVEVARVLLDHGAGINT--HSNEFKESALTLACYKGHLDMVRFLLEAG-ADQ 387
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFP----------------------------- 179
+ E +TAL+ A GH + LL+
Sbjct: 388 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLI 447
Query: 180 --GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 219
G +LE N G+T LM+AA +G + + L+ GA+++A+
Sbjct: 448 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 489
>gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1
[Homo sapiens]
Length = 2542
Score = 68.9 bits (167), Expect = 1e-11
Identities = 63/197 (31%), Positives = 87/197 (44%), Gaps = 11/197 (5%)
Query: 48 DTRSIASDDSFYPFEDEEEHGVESAESVPEGVPESVPETATLLRAAC-ANNVGLLRTLVR 106
DTRS+A S D + + V V E E +LL AC A L + L+
Sbjct: 205 DTRSLAEACS-----DGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 259
Query: 107 RGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAG 166
+VE+ ++ T L+ A G++D +V L DVN Q + GNTAL A G
Sbjct: 260 MHANVED--RGNKGDITPLMAASSGGYLD-IVKLLLLHDADVNSQSATGNTALTYACAGG 316
Query: 167 HAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMS 226
I LLN G ++E N G T LM+AA G + R L+ GA ++ S
Sbjct: 317 FVDIVKVLLN--EGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKES 374
Query: 227 PQEWATYTGRVDAVRLM 243
A Y G +D VR +
Sbjct: 375 ALTLACYKGHLDMVRFL 391
Score = 60.1 bits (144), Expect = 5e-09
Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 6/155 (3%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ A+ + +++ L+ V T G T L AC GFVD V L ++
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSAT---GNTALTYACAGGFVDIVKVLLN-EGANI 331
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
+ G+T L+ AA AGH + LL++ G++ N F +AL A +G D +R
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHS-NEFKESALTLACYKGHLDMVRF 390
Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
L+ AGAD + + E A G V+ RL+
Sbjct: 391 LLEAGADQEHKTDEMHTALME-ACMDGHVEVARLL 424
Score = 55.5 bits (132), Expect = 1e-07
Identities = 43/155 (27%), Positives = 74/155 (47%), Gaps = 3/155 (1%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ AA A +VG++ L+ +G +E +++R T L +AC G + VV L +
Sbjct: 1092 LILAATAGHVGVVEILLDKGGDIEA--QSERTKDTPLSLACSGGRQE-VVDLLLARGANK 1148
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
++ T L AA G+ I LLN ++ + G + LM AAM G ++
Sbjct: 1149 EHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKL 1208
Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
L+ G+D++A+ + A + GR + V L+
Sbjct: 1209 LLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 1243
Score = 50.1 bits (118), Expect = 5e-06
Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 34/162 (20%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ AA A +V + R L+ G + ++ + L +ACY G +D V L E D
Sbjct: 342 LMEAASAGHVEVARVLLDHGAGINT--HSNEFKESALTLACYKGHLDMVRFLLEAG-ADQ 398
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFP----------------------------- 179
+ E +TAL+ A GH + LL+
Sbjct: 399 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLI 458
Query: 180 --GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 219
G +LE N G+T LM+AA +G + + L+ GA+++A+
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500
Score = 48.5 bits (114), Expect = 1e-05
Identities = 42/138 (30%), Positives = 69/138 (50%), Gaps = 5/138 (3%)
Query: 82 SVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALA 141
+V + L AA V +++ L+ G + ++ + G + L++A +G V V L
Sbjct: 1152 NVSDYTPLSLAASGGYVNIIKILLNAGAEIN-SRTGSKLGISPLMLAAMNGHVPAVKLLL 1210
Query: 142 ECPHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 200
+ D+N Q ++ NTAL A G A + + LL+ ++E R G T LM+AA
Sbjct: 1211 DMGS-DINAQIETNRNTALTLACFQGRAEVVSLLLDR--KANVEHRAKTGLTPLMEAASG 1267
Query: 201 GRTDCIRALMLAGADVHA 218
G + R L+ GADV+A
Sbjct: 1268 GYAEVGRVLLDKGADVNA 1285
Score = 47.0 bits (110), Expect = 4e-05
Identities = 46/163 (28%), Positives = 69/163 (42%), Gaps = 10/163 (6%)
Query: 81 ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 140
E ETA L A C + L++ G +E T L+ A G ++ V L
Sbjct: 502 EETQETALTL-ACCGGFSEVADFLIKAGADIELGCSTP------LMEASQEGHLELVKYL 554
Query: 141 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 200
+V+ + G+TAL A + GH + + LL G DLE + G T LMKAA
Sbjct: 555 L-ASGANVHATTATGDTALTYACENGHTDVADVLLQ--AGADLEHESEGGRTPLMKAARA 611
Query: 201 GRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
G ++ L+ GA+V+ + A G + V L+
Sbjct: 612 GHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELL 654
Score = 46.2 bits (108), Expect = 7e-05
Identities = 32/97 (32%), Positives = 51/97 (52%), Gaps = 3/97 (3%)
Query: 81 ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 140
ES L++AA A ++ ++ L+ +G +V A T N T + +AC G + VV L
Sbjct: 597 ESEGGRTPLMKAARAGHLCTVQFLISKGANVNRA--TANNDHTVVSLACAGGHL-AVVEL 653
Query: 141 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNY 177
D + +G+T LI AA+ GH + +YLL+Y
Sbjct: 654 LLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDY 690
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 3/101 (2%)
Query: 144 PHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGR 202
P VD++ +S +TAL A GH + + L+ +E R+ GFT L+ AA G
Sbjct: 1043 PSVDIDAHTESNHDTALTLACAGGHEELVSVLIAR--DAKIEHRDKKGFTPLILAATAGH 1100
Query: 203 TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
+ L+ G D+ A+ R +P A GR + V L+
Sbjct: 1101 VGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLL 1141
Score = 36.2 bits (82), Expect = 0.070
Identities = 36/154 (23%), Positives = 58/154 (37%), Gaps = 36/154 (23%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ A+ ++ L++ L+ G +V T G T L AC +G D L + D+
Sbjct: 539 LMEASQEGHLELVKYLLASGANVHATTAT---GDTALTYACENGHTDVADVLLQAG-ADL 594
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLN-------------------------------- 176
+ G T L+ AA+AGH +L++
Sbjct: 595 EHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELL 654
Query: 177 YFPGLDLERRNAFGFTALMKAAMQGRTDCIRALM 210
G D R G T L++AA G T+ + L+
Sbjct: 655 LAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLL 688
Score = 33.9 bits (76), Expect = 0.35
Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 10/109 (9%)
Query: 79 VPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVV 138
VP S T+ AA + L+ RG ++ ++ G T L +A G D V
Sbjct: 1288 VPSSRDTALTI--AADKGHYKFCELLIHRGAHIDVR---NKKGNTPLWLASNGGHFDVVQ 1342
Query: 139 ALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYL---LNYFPGLDLE 184
L + DV+ D+ T L++A + GH + YL +N FP D+E
Sbjct: 1343 LLVQAG-ADVDAADNRKITPLMSAFRKGHVKVVQYLVKEVNQFPS-DIE 1389
Score = 33.1 bits (74), Expect = 0.59
Identities = 41/161 (25%), Positives = 69/161 (42%), Gaps = 13/161 (8%)
Query: 88 TLLRAACANN-VGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAEC-PH 145
T L AC+ ++ L+ RG + E +D T L +A G+V+ + L
Sbjct: 1124 TPLSLACSGGRQEVVDLLLARGANKEHRNVSDY---TPLSLAASGGYVNIIKILLNAGAE 1180
Query: 146 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE---RRNAFGFTALMKAAMQGR 202
++ G + L+ AA GH LL+ ++ + RN TAL A QGR
Sbjct: 1181 INSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRN----TALTLACFQGR 1236
Query: 203 TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
+ + L+ A+V R + G++P A G + R++
Sbjct: 1237 AEVVSLLLDRKANVEHR-AKTGLTPLMEAASGGYAEVGRVL 1276
>gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]
Length = 2617
Score = 68.9 bits (167), Expect = 1e-11
Identities = 63/197 (31%), Positives = 87/197 (44%), Gaps = 11/197 (5%)
Query: 48 DTRSIASDDSFYPFEDEEEHGVESAESVPEGVPESVPETATLLRAAC-ANNVGLLRTLVR 106
DTRS+A S D + + V V E E +LL AC A L + L+
Sbjct: 205 DTRSLAEACS-----DGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 259
Query: 107 RGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAG 166
+VE+ ++ T L+ A G++D +V L DVN Q + GNTAL A G
Sbjct: 260 MHANVED--RGNKGDITPLMAASSGGYLD-IVKLLLLHDADVNSQSATGNTALTYACAGG 316
Query: 167 HAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMS 226
I LLN G ++E N G T LM+AA G + R L+ GA ++ S
Sbjct: 317 FVDIVKVLLN--EGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKES 374
Query: 227 PQEWATYTGRVDAVRLM 243
A Y G +D VR +
Sbjct: 375 ALTLACYKGHLDMVRFL 391
Score = 60.1 bits (144), Expect = 5e-09
Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 6/155 (3%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ A+ + +++ L+ V T G T L AC GFVD V L ++
Sbjct: 276 LMAASSGGYLDIVKLLLLHDADVNSQSAT---GNTALTYACAGGFVDIVKVLLN-EGANI 331
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
+ G+T L+ AA AGH + LL++ G++ N F +AL A +G D +R
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHS-NEFKESALTLACYKGHLDMVRF 390
Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
L+ AGAD + + E A G V+ RL+
Sbjct: 391 LLEAGADQEHKTDEMHTALME-ACMDGHVEVARLL 424
Score = 55.5 bits (132), Expect = 1e-07
Identities = 43/155 (27%), Positives = 74/155 (47%), Gaps = 3/155 (1%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ AA A +VG++ L+ +G +E +++R T L +AC G + VV L +
Sbjct: 1092 LILAATAGHVGVVEILLDKGGDIEA--QSERTKDTPLSLACSGGRQE-VVDLLLARGANK 1148
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
++ T L AA G+ I LLN ++ + G + LM AAM G ++
Sbjct: 1149 EHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKL 1208
Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
L+ G+D++A+ + A + GR + V L+
Sbjct: 1209 LLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 1243
Score = 50.1 bits (118), Expect = 5e-06
Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 34/162 (20%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ AA A +V + R L+ G + ++ + L +ACY G +D V L E D
Sbjct: 342 LMEAASAGHVEVARVLLDHGAGINT--HSNEFKESALTLACYKGHLDMVRFLLEAG-ADQ 398
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFP----------------------------- 179
+ E +TAL+ A GH + LL+
Sbjct: 399 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLI 458
Query: 180 --GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 219
G +LE N G+T LM+AA +G + + L+ GA+++A+
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500
Score = 48.5 bits (114), Expect = 1e-05
Identities = 42/138 (30%), Positives = 69/138 (50%), Gaps = 5/138 (3%)
Query: 82 SVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALA 141
+V + L AA V +++ L+ G + ++ + G + L++A +G V V L
Sbjct: 1152 NVSDYTPLSLAASGGYVNIIKILLNAGAEIN-SRTGSKLGISPLMLAAMNGHVPAVKLLL 1210
Query: 142 ECPHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 200
+ D+N Q ++ NTAL A G A + + LL+ ++E R G T LM+AA
Sbjct: 1211 DMGS-DINAQIETNRNTALTLACFQGRAEVVSLLLDR--KANVEHRAKTGLTPLMEAASG 1267
Query: 201 GRTDCIRALMLAGADVHA 218
G + R L+ GADV+A
Sbjct: 1268 GYAEVGRVLLDKGADVNA 1285
Score = 47.0 bits (110), Expect = 4e-05
Identities = 46/163 (28%), Positives = 69/163 (42%), Gaps = 10/163 (6%)
Query: 81 ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 140
E ETA L A C + L++ G +E T L+ A G ++ V L
Sbjct: 502 EETQETALTL-ACCGGFSEVADFLIKAGADIELGCSTP------LMEASQEGHLELVKYL 554
Query: 141 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 200
+V+ + G+TAL A + GH + + LL G DLE + G T LMKAA
Sbjct: 555 L-ASGANVHATTATGDTALTYACENGHTDVADVLLQ--AGADLEHESEGGRTPLMKAARA 611
Query: 201 GRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
G ++ L+ GA+V+ + A G + V L+
Sbjct: 612 GHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELL 654
Score = 46.2 bits (108), Expect = 7e-05
Identities = 32/97 (32%), Positives = 51/97 (52%), Gaps = 3/97 (3%)
Query: 81 ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 140
ES L++AA A ++ ++ L+ +G +V A T N T + +AC G + VV L
Sbjct: 597 ESEGGRTPLMKAARAGHLCTVQFLISKGANVNRA--TANNDHTVVSLACAGGHL-AVVEL 653
Query: 141 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNY 177
D + +G+T LI AA+ GH + +YLL+Y
Sbjct: 654 LLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDY 690
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 3/101 (2%)
Query: 144 PHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGR 202
P VD++ +S +TAL A GH + + L+ +E R+ GFT L+ AA G
Sbjct: 1043 PSVDIDAHTESNHDTALTLACAGGHEELVSVLIAR--DAKIEHRDKKGFTPLILAATAGH 1100
Query: 203 TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
+ L+ G D+ A+ R +P A GR + V L+
Sbjct: 1101 VGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLL 1141
Score = 36.2 bits (82), Expect = 0.070
Identities = 36/154 (23%), Positives = 58/154 (37%), Gaps = 36/154 (23%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ A+ ++ L++ L+ G +V T G T L AC +G D L + D+
Sbjct: 539 LMEASQEGHLELVKYLLASGANVHATTAT---GDTALTYACENGHTDVADVLLQAG-ADL 594
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLN-------------------------------- 176
+ G T L+ AA+AGH +L++
Sbjct: 595 EHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELL 654
Query: 177 YFPGLDLERRNAFGFTALMKAAMQGRTDCIRALM 210
G D R G T L++AA G T+ + L+
Sbjct: 655 LAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLL 688
Score = 33.9 bits (76), Expect = 0.35
Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 10/109 (9%)
Query: 79 VPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVV 138
VP S T+ AA + L+ RG ++ ++ G T L +A G D V
Sbjct: 1288 VPSSRDTALTI--AADKGHYKFCELLIHRGAHIDVR---NKKGNTPLWLASNGGHFDVVQ 1342
Query: 139 ALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYL---LNYFPGLDLE 184
L + DV+ D+ T L++A + GH + YL +N FP D+E
Sbjct: 1343 LLVQAG-ADVDAADNRKITPLMSAFRKGHVKVVQYLVKEVNQFPS-DIE 1389
Score = 33.1 bits (74), Expect = 0.59
Identities = 41/161 (25%), Positives = 69/161 (42%), Gaps = 13/161 (8%)
Query: 88 TLLRAACANN-VGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAEC-PH 145
T L AC+ ++ L+ RG + E +D T L +A G+V+ + L
Sbjct: 1124 TPLSLACSGGRQEVVDLLLARGANKEHRNVSDY---TPLSLAASGGYVNIIKILLNAGAE 1180
Query: 146 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE---RRNAFGFTALMKAAMQGR 202
++ G + L+ AA GH LL+ ++ + RN TAL A QGR
Sbjct: 1181 INSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRN----TALTLACFQGR 1236
Query: 203 TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
+ + L+ A+V R + G++P A G + R++
Sbjct: 1237 AEVVSLLLDRKANVEHR-AKTGLTPLMEAASGGYAEVGRVL 1276
>gi|169208819 PREDICTED: similar to kinase D-interacting substrate
220 [Homo sapiens]
Length = 380
Score = 66.2 bits (160), Expect = 6e-11
Identities = 86/315 (27%), Positives = 124/315 (39%), Gaps = 28/315 (8%)
Query: 101 LRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALI 160
+R L+ +G +V D GRT L +AC G +D V L + D DS GN+ ++
Sbjct: 67 VRLLLEQGAAVNLR---DERGRTALSLACERGHLDAVQLLVQFSG-DPEAADSAGNSPVM 122
Query: 161 TAAQAGHAIITNYLLNYFP--GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHA 218
AA GH + +L+ F GL L+R N G TAL AA +G C++AL A
Sbjct: 123 WAAACGHGAVLEFLVRSFRRLGLRLDRTNRAGLTALQLAAARGHGTCVQALTGPWGRAAA 182
Query: 219 RDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKN 278
RG + + GR + RP P + RP L AA G
Sbjct: 183 AAAARGSNSD---SPPGRPAPAASPEH--RRPSPRRL---PRPLLARFARAAGGHGGEAG 234
Query: 279 CLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKR 338
+ + + + R PE G + + T + + P SP S G
Sbjct: 235 SAGKNSGRHRAQGSER----PELGRSMSLALGAVTEEEAARLRAGALMALPNSPQSSGTG 290
Query: 339 RLAVQEILAA---RAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALG-SR 394
R QE+L A+ P GG G GR G R S +P +G +
Sbjct: 291 RWRSQEVLEGAPPTLAQAPIGLSPHPEGGPGS-GRLG-----LRRRSTAPDIPSLVGEAP 344
Query: 395 GPAAPAPRKASLLPL 409
GP + +A+ LP+
Sbjct: 345 GPESGPELEANALPV 359
>gi|169208593 PREDICTED: similar to kinase D-interacting substrate
220 [Homo sapiens]
Length = 380
Score = 66.2 bits (160), Expect = 6e-11
Identities = 86/315 (27%), Positives = 124/315 (39%), Gaps = 28/315 (8%)
Query: 101 LRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALI 160
+R L+ +G +V D GRT L +AC G +D V L + D DS GN+ ++
Sbjct: 67 VRLLLEQGAAVNLR---DERGRTALSLACERGHLDAVQLLVQFSG-DPEAADSAGNSPVM 122
Query: 161 TAAQAGHAIITNYLLNYFP--GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHA 218
AA GH + +L+ F GL L+R N G TAL AA +G C++AL A
Sbjct: 123 WAAACGHGAVLEFLVRSFRRLGLRLDRTNRAGLTALQLAAARGHGTCVQALTGPWGRAAA 182
Query: 219 RDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKN 278
RG + + GR + RP P + RP L AA G
Sbjct: 183 AAAARGSNSD---SPPGRPAPAASPEH--RRPSPRRL---PRPLLARFARAAGGHGGEAG 234
Query: 279 CLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKR 338
+ + + + R PE G + + T + + P SP S G
Sbjct: 235 SAGKNSGRHRAQGSER----PELGRSMSLALGAVTEEEAARLRAGALMALPNSPQSSGTG 290
Query: 339 RLAVQEILAA---RAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALG-SR 394
R QE+L A+ P GG G GR G R S +P +G +
Sbjct: 291 RWRSQEVLEGAPPTLAQAPIGLSPHPEGGPGS-GRLG-----LRRRSTAPDIPSLVGEAP 344
Query: 395 GPAAPAPRKASLLPL 409
GP + +A+ LP+
Sbjct: 345 GPESGPELEANALPV 359
>gi|55741641 kinase D-interacting substrate of 220 kDa [Homo
sapiens]
Length = 1771
Score = 66.2 bits (160), Expect = 6e-11
Identities = 61/187 (32%), Positives = 91/187 (48%), Gaps = 14/187 (7%)
Query: 97 NVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGN 156
N+ L+ L+ + V+E E G+T L++A G ++ V L + + N +D +
Sbjct: 17 NIPALKALLEKCKDVDERNEC---GQTPLMIAAEQGNLEIVKELIK-NGANCNLEDLDNW 72
Query: 157 TALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADV 216
TALI+A++ GH I LL G++LE R+ G+TALM A +GRTD + L+ GA+
Sbjct: 73 TALISASKEGHVHIVEELLKC--GVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANP 130
Query: 217 HARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGS 276
+ P WA G D V L LL+ +KY P AARK G
Sbjct: 131 SVTG-LYSVYPIIWAAGRGHADIVHL---LLQNGAKVNCSDKY--GTTPLVWAARK--GH 182
Query: 277 KNCLQRL 283
C++ L
Sbjct: 183 LECVKHL 189
Score = 56.2 bits (134), Expect = 7e-08
Identities = 46/156 (29%), Positives = 76/156 (48%), Gaps = 7/156 (4%)
Query: 86 TATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPH 145
T L+ AA ++ ++ L+ G V++ N T LIVA G+ +V + + +
Sbjct: 171 TTPLVWAARKGHLECVKHLLAMGADVDQE---GANSMTALIVAVKGGYTQSVKEILK-RN 226
Query: 146 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDC 205
+VN D +GNTAL+ A++ GH I LL+ +++ R+ G T L+ A G +
Sbjct: 227 PNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRS--GDTVLIGAVRGGHVEI 284
Query: 206 IRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVR 241
+RAL+ AD+ R + + WA G VR
Sbjct: 285 VRALLQKYADIDIRG-QDNKTALYWAVEKGNATMVR 319
Score = 52.4 bits (124), Expect = 9e-07
Identities = 43/137 (31%), Positives = 68/137 (49%), Gaps = 8/137 (5%)
Query: 81 ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTV-VA 139
E + L+ A+ +V ++ L++ GV++E D G T L+ ACY G D V +
Sbjct: 67 EDLDNWTALISASKEGHVHIVEELLKCGVNLEHR---DMGGWTALMWACYKGRTDVVELL 123
Query: 140 LAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAM 199
L+ + V S +I AA GHA I + LL G + + +G T L+ AA
Sbjct: 124 LSHGANPSVTGLYSV--YPIIWAAGRGHADIVHLLLQN--GAKVNCSDKYGTTPLVWAAR 179
Query: 200 QGRTDCIRALMLAGADV 216
+G +C++ L+ GADV
Sbjct: 180 KGHLECVKHLLAMGADV 196
Score = 44.3 bits (103), Expect = 3e-04
Identities = 42/133 (31%), Positives = 64/133 (48%), Gaps = 7/133 (5%)
Query: 118 DRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNY 177
DR+G T LI A G V+ V AL + + D++ + + TAL A + G+A + +L
Sbjct: 266 DRSGDTVLIGAVRGGHVEIVRALLQ-KYADIDIRGQDNKTALYWAVEKGNATMVRDILQC 324
Query: 178 FPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRV 237
P D E G T L+KA + + L+ GA V A D ++G +P A R
Sbjct: 325 NP--DTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVD-KKGDTPLHIAI---RG 378
Query: 238 DAVRLMQRLLERP 250
+ +L + LL P
Sbjct: 379 RSRKLAELLLRNP 391
>gi|70995267 ankyrin repeat domain 29 [Homo sapiens]
Length = 301
Score = 65.5 bits (158), Expect = 1e-10
Identities = 50/152 (32%), Positives = 73/152 (48%), Gaps = 6/152 (3%)
Query: 92 AACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQ 151
AA N+ LL+ L+ G + + D +G T L+VA Y G +D V L D+N Q
Sbjct: 19 AARRGNLALLKLLLNSGRVDVDCR--DSHGTTLLMVAAYAGHIDCVRELV-LQGADINLQ 75
Query: 152 DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALML 211
G TAL AAQ GH + +L + G E R G TAL+ A+ G + L+
Sbjct: 76 RESGTTALFFAAQQGHNDVVRFLFGF--GASTEFRTKDGGTALLAASQYGHMQVVETLLK 133
Query: 212 AGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
GA++H + G + A G +D +RL+
Sbjct: 134 HGANIHDQ-LYDGATALFLAAQGGYLDVIRLL 164
Score = 62.0 bits (149), Expect = 1e-09
Identities = 52/159 (32%), Positives = 78/159 (49%), Gaps = 9/159 (5%)
Query: 86 TATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPH 145
T L+ AA A ++ +R LV +G + +E+ G T L A G D V L
Sbjct: 47 TTLLMVAAYAGHIDCVRELVLQGADINLQRES---GTTALFFAAQQGHNDVVRFLFGFG- 102
Query: 146 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDC 205
++ +G TAL+ A+Q GH + LL + G ++ + G TAL AA G D
Sbjct: 103 ASTEFRTKDGGTALLAASQYGHMQVVETLLKH--GANIHDQLYDGATALFLAAQGGYLDV 160
Query: 206 IRALMLAGADVHARDPRR-GMSPQEWATYTGRVDAVRLM 243
IR L+ +GA V+ PR+ G +P A+ G + VR+M
Sbjct: 161 IRLLLASGAKVN--QPRQDGTAPLWIASQMGHSEVVRVM 197
Score = 51.2 bits (121), Expect = 2e-06
Identities = 42/155 (27%), Positives = 72/155 (46%), Gaps = 8/155 (5%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
LL A+ ++ ++ TL++ G ++ + +G T L +A G++D V+ L V
Sbjct: 116 LLAASQYGHMQVVETLLKHGANIHDQLY---DGATALFLAAQGGYLD-VIRLLLASGAKV 171
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
N +G L A+Q GH+ + +L G D + G TAL+KAA +G D I+
Sbjct: 172 NQPRQDGTAPLWIASQMGHSEVVRVML--LRGADRDAARNDGTTALLKAANKGYNDVIKE 229
Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
L+ + + G S A +G + V L+
Sbjct: 230 LLKFSPTLGIL--KNGTSALHAAVLSGNIKTVALL 262
Score = 45.8 bits (107), Expect = 9e-05
Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
Query: 158 ALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVH 217
A AA+ G+ + LLN +D++ R++ G T LM AA G DC+R L+L GAD++
Sbjct: 15 AAFWAARRGNLALLKLLLNS-GRVDVDCRDSHGTTLLMVAAYAGHIDCVRELVLQGADIN 73
Query: 218 ARDPRRGMSPQEWATYTGRVDAVRLM 243
+ G + +A G D VR +
Sbjct: 74 LQ-RESGTTALFFAAQQGHNDVVRFL 98
>gi|169208169 PREDICTED: similar to kinase D-interacting substrate
220 [Homo sapiens]
Length = 380
Score = 63.5 bits (153), Expect = 4e-10
Identities = 86/317 (27%), Positives = 119/317 (37%), Gaps = 31/317 (9%)
Query: 101 LRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALI 160
+R L+ +G +V D GRT L +AC G +D V L + D DS GN+ ++
Sbjct: 67 VRLLLEQGAAVNLR---DERGRTALSLACERGHLDAVQLLVQFSG-DPEAADSAGNSPVM 122
Query: 161 TAAQAGHAIITNYLLNYFP--GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHA 218
AA GH + +L+ F GL L+R N G TAL AA +G C++AL A
Sbjct: 123 WAAACGHGAVLEFLVRSFRRLGLRLDRTNRAGLTALQLAAARGHGTCVQALTGPWGRAAA 182
Query: 219 RDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKN 278
RG + + GR + RP P + RP L AA G
Sbjct: 183 AAAARGSNSD---SPPGRPAPAASPEH--RRPSPRRL---PRPLLARFARAAGGHGGEAG 234
Query: 279 CLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKR 338
+ + + + R PE G + + T + + P SP S G
Sbjct: 235 SAGKNSGRHRAQGSER----PELGRSMSLALGAVTEEEAARLRAGALMALPNSPQSSGTG 290
Query: 339 RLAVQEILAA---RAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRG 395
R QE+L A+ P GG G GR G R S +P +G
Sbjct: 291 RWRSQEVLEGAPPTLAQAPIGLSPHPEGGPGS-GRLG-----LRRRSTAPDIPSLVGE-- 342
Query: 396 PAAPAPRKASLLPLQRL 412
AP P L L
Sbjct: 343 --APGPESGPELEANAL 357
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 63.2 bits (152), Expect = 5e-10
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)
Query: 114 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 172
A+ D +G+T L A G + V L C H +N +D +GN L+ A Q GH+ I +
Sbjct: 115 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 172
Query: 173 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 220
+LL++ G D+ RN G TALM A G ++ + AL+ GAD++ D
Sbjct: 173 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 218
Score = 43.5 bits (101), Expect = 4e-04
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Query: 125 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 184
L+ A +G + V +L DSEG TA AA GH ++ + G+D+
Sbjct: 26 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 83
Query: 185 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
++ G +AL AA +CIR L+ + + D G + +A G + AV+++
Sbjct: 84 AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 141
Score = 36.6 bits (83), Expect = 0.054
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)
Query: 153 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 212
++ + L+ A + G A LL G + ++ G TA AA +G +C+R ++
Sbjct: 20 NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 78
Query: 213 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 272
G DV A+D G S A + +R +LL+ CP + + + A
Sbjct: 79 GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 127
Query: 273 PAGSKNCLQ 281
A ++ CLQ
Sbjct: 128 YAAAQGCLQ 136
Score = 30.0 bits (66), Expect = 5.0
Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Query: 113 EAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITN 172
+ +++GRT L++AC G + V AL + D+N DS G AL + + +A I +
Sbjct: 180 DVNSRNKSGRTALMLACEIGSSNAVEALIK-KGADLNLVDSLGYNALHYSKLSENAGIQS 238
Query: 173 YLLN 176
LL+
Sbjct: 239 LLLS 242
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 63.2 bits (152), Expect = 5e-10
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)
Query: 114 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 172
A+ D +G+T L A G + V L C H +N +D +GN L+ A Q GH+ I +
Sbjct: 104 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 161
Query: 173 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 220
+LL++ G D+ RN G TALM A G ++ + AL+ GAD++ D
Sbjct: 162 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 207
Score = 43.5 bits (101), Expect = 4e-04
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Query: 125 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 184
L+ A +G + V +L DSEG TA AA GH ++ + G+D+
Sbjct: 15 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 72
Query: 185 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
++ G +AL AA +CIR L+ + + D G + +A G + AV+++
Sbjct: 73 AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 130
Score = 36.6 bits (83), Expect = 0.054
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)
Query: 153 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 212
++ + L+ A + G A LL G + ++ G TA AA +G +C+R ++
Sbjct: 9 NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 67
Query: 213 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 272
G DV A+D G S A + +R +LL+ CP + + + A
Sbjct: 68 GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 116
Query: 273 PAGSKNCLQ 281
A ++ CLQ
Sbjct: 117 YAAAQGCLQ 125
Score = 30.0 bits (66), Expect = 5.0
Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Query: 113 EAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITN 172
+ +++GRT L++AC G + V AL + D+N DS G AL + + +A I +
Sbjct: 169 DVNSRNKSGRTALMLACEIGSSNAVEALIK-KGADLNLVDSLGYNALHYSKLSENAGIQS 227
Query: 173 YLLN 176
LL+
Sbjct: 228 LLLS 231
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 63.2 bits (152), Expect = 5e-10
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)
Query: 114 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 172
A+ D +G+T L A G + V L C H +N +D +GN L+ A Q GH+ I +
Sbjct: 112 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 169
Query: 173 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 220
+LL++ G D+ RN G TALM A G ++ + AL+ GAD++ D
Sbjct: 170 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 215
Score = 43.5 bits (101), Expect = 4e-04
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Query: 125 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 184
L+ A +G + V +L DSEG TA AA GH ++ + G+D+
Sbjct: 23 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 80
Query: 185 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
++ G +AL AA +CIR L+ + + D G + +A G + AV+++
Sbjct: 81 AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 138
Score = 36.6 bits (83), Expect = 0.054
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)
Query: 153 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 212
++ + L+ A + G A LL G + ++ G TA AA +G +C+R ++
Sbjct: 17 NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 75
Query: 213 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 272
G DV A+D G S A + +R +LL+ CP + + + A
Sbjct: 76 GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 124
Query: 273 PAGSKNCLQ 281
A ++ CLQ
Sbjct: 125 YAAAQGCLQ 133
Score = 30.0 bits (66), Expect = 5.0
Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Query: 113 EAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITN 172
+ +++GRT L++AC G + V AL + D+N DS G AL + + +A I +
Sbjct: 177 DVNSRNKSGRTALMLACEIGSSNAVEALIK-KGADLNLVDSLGYNALHYSKLSENAGIQS 235
Query: 173 YLLN 176
LL+
Sbjct: 236 LLLS 239
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 63.2 bits (152), Expect = 5e-10
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)
Query: 114 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 172
A+ D +G+T L A G + V L C H +N +D +GN L+ A Q GH+ I +
Sbjct: 112 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 169
Query: 173 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 220
+LL++ G D+ RN G TALM A G ++ + AL+ GAD++ D
Sbjct: 170 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 215
Score = 43.5 bits (101), Expect = 4e-04
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Query: 125 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 184
L+ A +G + V +L DSEG TA AA GH ++ + G+D+
Sbjct: 23 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 80
Query: 185 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
++ G +AL AA +CIR L+ + + D G + +A G + AV+++
Sbjct: 81 AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 138
Score = 36.6 bits (83), Expect = 0.054
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)
Query: 153 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 212
++ + L+ A + G A LL G + ++ G TA AA +G +C+R ++
Sbjct: 17 NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 75
Query: 213 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 272
G DV A+D G S A + +R +LL+ CP + + + A
Sbjct: 76 GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 124
Query: 273 PAGSKNCLQ 281
A ++ CLQ
Sbjct: 125 YAAAQGCLQ 133
Score = 30.0 bits (66), Expect = 5.0
Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Query: 113 EAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITN 172
+ +++GRT L++AC G + V AL + D+N DS G AL + + +A I +
Sbjct: 177 DVNSRNKSGRTALMLACEIGSSNAVEALIK-KGADLNLVDSLGYNALHYSKLSENAGIQS 235
Query: 173 YLLN 176
LL+
Sbjct: 236 LLLS 239
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 63.2 bits (152), Expect = 5e-10
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)
Query: 114 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 172
A+ D +G+T L A G + V L C H +N +D +GN L+ A Q GH+ I +
Sbjct: 112 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 169
Query: 173 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 220
+LL++ G D+ RN G TALM A G ++ + AL+ GAD++ D
Sbjct: 170 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 215
Score = 43.5 bits (101), Expect = 4e-04
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Query: 125 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 184
L+ A +G + V +L DSEG TA AA GH ++ + G+D+
Sbjct: 23 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 80
Query: 185 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
++ G +AL AA +CIR L+ + + D G + +A G + AV+++
Sbjct: 81 AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 138
Score = 36.6 bits (83), Expect = 0.054
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)
Query: 153 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 212
++ + L+ A + G A LL G + ++ G TA AA +G +C+R ++
Sbjct: 17 NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 75
Query: 213 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 272
G DV A+D G S A + +R +LL+ CP + + + A
Sbjct: 76 GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 124
Query: 273 PAGSKNCLQ 281
A ++ CLQ
Sbjct: 125 YAAAQGCLQ 133
Score = 30.0 bits (66), Expect = 5.0
Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Query: 113 EAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITN 172
+ +++GRT L++AC G + V AL + D+N DS G AL + + +A I +
Sbjct: 177 DVNSRNKSGRTALMLACEIGSSNAVEALIK-KGADLNLVDSLGYNALHYSKLSENAGIQS 235
Query: 173 YLLN 176
LL+
Sbjct: 236 LLLS 239
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 63.2 bits (152), Expect = 5e-10
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 5/108 (4%)
Query: 114 AQETDRNGRTGLIVACYHGFVDTVVALAECPHVD-VNWQDSEGNTALITAAQAGHAIITN 172
A+ D +G+T L A G + V L C H +N +D +GN L+ A Q GH+ I +
Sbjct: 112 AESVDSSGKTALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICH 169
Query: 173 YLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARD 220
+LL++ G D+ RN G TALM A G ++ + AL+ GAD++ D
Sbjct: 170 FLLDH--GADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVD 215
Score = 43.5 bits (101), Expect = 4e-04
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Query: 125 LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE 184
L+ A +G + V +L DSEG TA AA GH ++ + G+D+
Sbjct: 23 LLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITH--GVDVT 80
Query: 185 RRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
++ G +AL AA +CIR L+ + + D G + +A G + AV+++
Sbjct: 81 AQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 138
Score = 36.6 bits (83), Expect = 0.054
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)
Query: 153 SEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLA 212
++ + L+ A + G A LL G + ++ G TA AA +G +C+R ++
Sbjct: 17 NKNDDRLLQAVENGDAEKVASLLGK-KGASATKHDSEGKTAFHLAAAKGHVECLRVMITH 75
Query: 213 GADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARK 272
G DV A+D G S A + +R +LL+ CP + + + A
Sbjct: 76 GVDVTAQD-TTGHSALHLAAKNSHHECIR---KLLQSKCPAE-------SVDSSGKTALH 124
Query: 273 PAGSKNCLQ 281
A ++ CLQ
Sbjct: 125 YAAAQGCLQ 133
Score = 30.0 bits (66), Expect = 5.0
Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Query: 113 EAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITN 172
+ +++GRT L++AC G + V AL + D+N DS G AL + + +A I +
Sbjct: 177 DVNSRNKSGRTALMLACEIGSSNAVEALIK-KGADLNLVDSLGYNALHYSKLSENAGIQS 235
Query: 173 YLLN 176
LL+
Sbjct: 236 LLLS 239
>gi|110431370 espin [Homo sapiens]
Length = 854
Score = 62.0 bits (149), Expect = 1e-09
Identities = 50/173 (28%), Positives = 81/173 (46%), Gaps = 7/173 (4%)
Query: 73 ESVPEGVPESVPETATLLRAACAN-NVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYH 131
E PEGV AT L AC ++ + + LV+ + A+ D G T L A
Sbjct: 159 EHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHARAHD--GMTPLHAAAQM 216
Query: 132 GFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGF 191
G +V L C V ++ QD +G TA+ AA GH + ++LL + + + +G
Sbjct: 217 GHSPVIVWLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEISAD---LWGG 273
Query: 192 TALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQ 244
T L AA G +C + L++ GA++ RD R G + + + + G R ++
Sbjct: 274 TPLHDAAENGELECCQILVVNGAELDVRD-RDGYTAADLSDFNGHSHCTRYLR 325
Score = 40.4 bits (93), Expect = 0.004
Identities = 36/136 (26%), Positives = 57/136 (41%), Gaps = 25/136 (18%)
Query: 383 PRAGLPPAL-GSRGPAAPA-PRKASLLPLQRLRRRSVRPGVVVP----RVRVSKAPAPTF 436
P AG P L GS P P P L ++ L G +P +V V K
Sbjct: 708 PAAGFQPLLNGSLVPVPPTTPAPGVQLDVEALIPTHDEQGRPIPEWKRQVMVRKMQLKMQ 767
Query: 437 QPERPARKGSTKDSGHLQIPKWR-------YKEAKEEKRKAEEAEKKRQAEAQKER---- 485
+ E RK +++ +P WR +E +E+KRK EE +K+ + +KE+
Sbjct: 768 EEEEQRRKEEEEEARLASMPAWRRDLLRKKLEEEREQKRKEEERQKQEELRREKEQSEKL 827
Query: 486 --------RTAPWKKR 493
+ APW+++
Sbjct: 828 RTLGYDESKLAPWQRQ 843
Score = 33.9 bits (76), Expect = 0.35
Identities = 39/152 (25%), Positives = 61/152 (40%), Gaps = 3/152 (1%)
Query: 92 AACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQ 151
AA A + LR LV A+ RNG T A G + + L V +
Sbjct: 43 AARAGKLHCLRFLVEEAALPAAARA--RNGATPAHDASATGHLACLQWLLSQGGCRVQDK 100
Query: 152 DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALML 211
D+ G T L AA+ GH + N+LL++ G D G + AA +G +R L+
Sbjct: 101 DNSGATVLHLAARFGHPEVVNWLLHHGGG-DPTAATDMGALPIHYAAAKGDFPSLRLLVE 159
Query: 212 AGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
+ + G +P A G ++ + +
Sbjct: 160 HYPEGVNAQTKNGATPLYLACQEGHLEVTQYL 191
>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
Length = 2603
Score = 60.1 bits (144), Expect = 5e-09
Identities = 53/159 (33%), Positives = 78/159 (49%), Gaps = 9/159 (5%)
Query: 88 TLLRAACAN-NVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHV 146
T L ACA + L++TL+ RG S+E D+ G T LI+A G V V L +
Sbjct: 1085 TALTLACAGGHEELVQTLLERGASIE---HRDKKGFTPLILAATAGHVGVVEILLD-NGA 1140
Query: 147 DVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDC 205
D+ Q + +T L A G + LL G + E RN +T L AA G +
Sbjct: 1141 DIEAQSERTKDTPLSLACSGGRQEVVELLL--ARGANKEHRNVSDYTPLSLAASGGYVNI 1198
Query: 206 IRALMLAGADVHAR-DPRRGMSPQEWATYTGRVDAVRLM 243
I+ L+ AGA++++R + G+SP A G AV+L+
Sbjct: 1199 IKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLL 1237
Score = 58.2 bits (139), Expect = 2e-08
Identities = 46/155 (29%), Positives = 69/155 (44%), Gaps = 6/155 (3%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ AA +V +++ L+ V T G T L AC G+VD V L E +
Sbjct: 305 LMAAANGGHVKIVKLLLAHKADVNAQSST---GNTALTYACAGGYVDVVKVLLESG-ASI 360
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
+ G+T L+ A AGH + LL G++ N F +AL A +G + +R
Sbjct: 361 EDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHS-NEFKESALTLACYKGHLEMVRF 419
Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
L+ AGAD + + E A G V+ RL+
Sbjct: 420 LLEAGADQEHKTDEMHTALME-ACMDGHVEVARLL 453
Score = 57.8 bits (138), Expect = 2e-08
Identities = 44/155 (28%), Positives = 74/155 (47%), Gaps = 3/155 (1%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ AA A +VG++ L+ G +E +++R T L +AC G + VV L +
Sbjct: 1120 LILAATAGHVGVVEILLDNGADIEA--QSERTKDTPLSLACSGGRQE-VVELLLARGANK 1176
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
++ T L AA G+ I LLN ++ + G + LM AAM G T ++
Sbjct: 1177 EHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKL 1236
Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
L+ G+D++A+ + A + GR + V L+
Sbjct: 1237 LLDMGSDINAQIETNRNTALTLACFQGRTEVVSLL 1271
Score = 57.4 bits (137), Expect = 3e-08
Identities = 52/166 (31%), Positives = 71/166 (42%), Gaps = 6/166 (3%)
Query: 79 VPESVPETATLLRAAC-ANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTV 137
V E E +LL AC A L + L+ +VE+ + T L+ A G V +
Sbjct: 260 VNEHTEEGESLLCLACSAGYYELAQVLLAMHANVED--RGIKGDITPLMAAANGGHVK-I 316
Query: 138 VALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKA 197
V L DVN Q S GNTAL A G+ + LL G +E N G T LM+A
Sbjct: 317 VKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLE--SGASIEDHNENGHTPLMEA 374
Query: 198 AMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
G + R L+ GA ++ S A Y G ++ VR +
Sbjct: 375 GSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFL 420
Score = 55.8 bits (133), Expect = 9e-08
Identities = 45/131 (34%), Positives = 67/131 (51%), Gaps = 10/131 (7%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L AAC +V L L+ RG S+EE + G T L+ A G + +VAL ++
Sbjct: 471 LTLAACGGHVELAALLIERGASLEEVND---EGYTPLMEAAREGH-EEMVALLLGQGANI 526
Query: 149 NWQDSEGN-TALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIR 207
N Q E TAL A G + ++L+ G D+E + T LM+AA +G + ++
Sbjct: 527 NAQTEETQETALTLACCGGFLEVADFLIK--AGADIELGCS---TPLMEAAQEGHLELVK 581
Query: 208 ALMLAGADVHA 218
L+ AGA+VHA
Sbjct: 582 YLLAAGANVHA 592
Score = 51.2 bits (121), Expect = 2e-06
Identities = 34/101 (33%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Query: 144 PHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGR 202
P +D++ Q +S +TAL A GH + LL G +E R+ GFT L+ AA G
Sbjct: 1071 PAIDIDAQTESNHDTALTLACAGGHEELVQTLLER--GASIEHRDKKGFTPLILAATAGH 1128
Query: 203 TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
+ L+ GAD+ A+ R +P A GR + V L+
Sbjct: 1129 VGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELL 1169
Score = 49.3 bits (116), Expect = 8e-06
Identities = 51/197 (25%), Positives = 81/197 (41%), Gaps = 17/197 (8%)
Query: 54 SDDSFYPFEDEEEHGVESAESVPEGV-------PESVPETATLLRAACANNVGLLRTLVR 106
+D+ + P + G E ++ G E ETA L A C + + L++
Sbjct: 497 NDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTL-ACCGGFLEVADFLIK 555
Query: 107 RGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAG 166
G +E T L+ A G ++ V L +V+ + G+TAL A + G
Sbjct: 556 AGADIELGCSTP------LMEAAQEGHLELVKYLLAAG-ANVHATTATGDTALTYACENG 608
Query: 167 HAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMS 226
H + + LL G DLE + G T LMKAA G ++ L+ GA+V+ +
Sbjct: 609 HTDVADVLLQ--AGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHT 666
Query: 227 PQEWATYTGRVDAVRLM 243
A G + V L+
Sbjct: 667 VLSLACAGGHLAVVELL 683
Score = 45.8 bits (107), Expect = 9e-05
Identities = 40/162 (24%), Positives = 66/162 (40%), Gaps = 34/162 (20%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ A A +V + R L+ G + ++ + L +ACY G ++ V L E D
Sbjct: 371 LMEAGSAGHVEVARLLLENGAGINT--HSNEFKESALTLACYKGHLEMVRFLLEAG-ADQ 427
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFP----------------------------- 179
+ E +TAL+ A GH + LL+
Sbjct: 428 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLI 487
Query: 180 --GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 219
G LE N G+T LM+AA +G + + L+ GA+++A+
Sbjct: 488 ERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQ 529
Score = 45.8 bits (107), Expect = 9e-05
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 3/97 (3%)
Query: 81 ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 140
ES L++AA A +V ++ L+ +G +V T N T L +AC G + VV L
Sbjct: 626 ESEGGRTPLMKAARAGHVCTVQFLISKGANVNRT--TANNDHTVLSLACAGGHL-AVVEL 682
Query: 141 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNY 177
D + +G+T LI AA+ GH + YLL+Y
Sbjct: 683 LLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDY 719
Score = 45.1 bits (105), Expect = 2e-04
Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 82 SVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALA 141
+V + L AA V +++ L+ G + ++ + G + L++A +G V L
Sbjct: 1180 NVSDYTPLSLAASGGYVNIIKILLNAGAEIN-SRTGSKLGISPLMLAAMNGHTAAVKLLL 1238
Query: 142 ECPHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 200
+ D+N Q ++ NTAL A G + + LL+ ++E R G T LM+AA
Sbjct: 1239 DMGS-DINAQIETNRNTALTLACFQGRTEVVSLLLDR--KANVEHRAKTGLTPLMEAASG 1295
Query: 201 GRTDCIRALMLAGADVHA 218
G + R L+ GADV+A
Sbjct: 1296 GYAEVGRVLLDKGADVNA 1313
Score = 36.6 bits (83), Expect = 0.054
Identities = 42/161 (26%), Positives = 70/161 (43%), Gaps = 13/161 (8%)
Query: 88 TLLRAACANN-VGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAEC-PH 145
T L AC+ ++ L+ RG + E +D T L +A G+V+ + L
Sbjct: 1152 TPLSLACSGGRQEVVELLLARGANKEHRNVSDY---TPLSLAASGGYVNIIKILLNAGAE 1208
Query: 146 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE---RRNAFGFTALMKAAMQGR 202
++ G + L+ AA GH LL+ ++ + RN TAL A QGR
Sbjct: 1209 INSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRN----TALTLACFQGR 1264
Query: 203 TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
T+ + L+ A+V R + G++P A G + R++
Sbjct: 1265 TEVVSLLLDRKANVEHR-AKTGLTPLMEAASGGYAEVGRVL 1304
Score = 33.5 bits (75), Expect = 0.46
Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 9/104 (8%)
Query: 79 VPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVV 138
VP S T+ AA + L+ RG ++ ++ G T L +A G +D V
Sbjct: 1316 VPSSRDTALTI--AADKGHYKFCELLIGRGAHIDVR---NKKGNTPLWLAANGGHLDVVQ 1370
Query: 139 ALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYL---LNYFP 179
L + DV+ D+ T L+ A + GH + YL +N FP
Sbjct: 1371 LLVQAG-ADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFP 1413
>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo
sapiens]
Length = 2352
Score = 60.1 bits (144), Expect = 5e-09
Identities = 53/159 (33%), Positives = 78/159 (49%), Gaps = 9/159 (5%)
Query: 88 TLLRAACAN-NVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHV 146
T L ACA + L++TL+ RG S+E D+ G T LI+A G V V L +
Sbjct: 834 TALTLACAGGHEELVQTLLERGASIE---HRDKKGFTPLILAATAGHVGVVEILLD-NGA 889
Query: 147 DVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDC 205
D+ Q + +T L A G + LL G + E RN +T L AA G +
Sbjct: 890 DIEAQSERTKDTPLSLACSGGRQEVVELLL--ARGANKEHRNVSDYTPLSLAASGGYVNI 947
Query: 206 IRALMLAGADVHAR-DPRRGMSPQEWATYTGRVDAVRLM 243
I+ L+ AGA++++R + G+SP A G AV+L+
Sbjct: 948 IKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLL 986
Score = 58.2 bits (139), Expect = 2e-08
Identities = 46/155 (29%), Positives = 69/155 (44%), Gaps = 6/155 (3%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ AA +V +++ L+ V T G T L AC G+VD V L E +
Sbjct: 305 LMAAANGGHVKIVKLLLAHKADVNAQSST---GNTALTYACAGGYVDVVKVLLESG-ASI 360
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
+ G+T L+ A AGH + LL G++ N F +AL A +G + +R
Sbjct: 361 EDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHS-NEFKESALTLACYKGHLEMVRF 419
Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
L+ AGAD + + E A G V+ RL+
Sbjct: 420 LLEAGADQEHKTDEMHTALME-ACMDGHVEVARLL 453
Score = 57.8 bits (138), Expect = 2e-08
Identities = 44/155 (28%), Positives = 74/155 (47%), Gaps = 3/155 (1%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ AA A +VG++ L+ G +E +++R T L +AC G + VV L +
Sbjct: 869 LILAATAGHVGVVEILLDNGADIEA--QSERTKDTPLSLACSGGRQE-VVELLLARGANK 925
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRA 208
++ T L AA G+ I LLN ++ + G + LM AAM G T ++
Sbjct: 926 EHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKL 985
Query: 209 LMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
L+ G+D++A+ + A + GR + V L+
Sbjct: 986 LLDMGSDINAQIETNRNTALTLACFQGRTEVVSLL 1020
Score = 57.4 bits (137), Expect = 3e-08
Identities = 52/166 (31%), Positives = 71/166 (42%), Gaps = 6/166 (3%)
Query: 79 VPESVPETATLLRAAC-ANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTV 137
V E E +LL AC A L + L+ +VE+ + T L+ A G V +
Sbjct: 260 VNEHTEEGESLLCLACSAGYYELAQVLLAMHANVED--RGIKGDITPLMAAANGGHVK-I 316
Query: 138 VALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKA 197
V L DVN Q S GNTAL A G+ + LL G +E N G T LM+A
Sbjct: 317 VKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLE--SGASIEDHNENGHTPLMEA 374
Query: 198 AMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
G + R L+ GA ++ S A Y G ++ VR +
Sbjct: 375 GSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFL 420
Score = 55.8 bits (133), Expect = 9e-08
Identities = 45/131 (34%), Positives = 67/131 (51%), Gaps = 10/131 (7%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L AAC +V L L+ RG S+EE + G T L+ A G + +VAL ++
Sbjct: 471 LTLAACGGHVELAALLIERGASLEEVND---EGYTPLMEAAREGH-EEMVALLLGQGANI 526
Query: 149 NWQDSEGN-TALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIR 207
N Q E TAL A G + ++L+ G D+E + T LM+AA +G + ++
Sbjct: 527 NAQTEETQETALTLACCGGFLEVADFLIK--AGADIELGCS---TPLMEAAQEGHLELVK 581
Query: 208 ALMLAGADVHA 218
L+ AGA+VHA
Sbjct: 582 YLLAAGANVHA 592
Score = 51.2 bits (121), Expect = 2e-06
Identities = 34/101 (33%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Query: 144 PHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGR 202
P +D++ Q +S +TAL A GH + LL G +E R+ GFT L+ AA G
Sbjct: 820 PAIDIDAQTESNHDTALTLACAGGHEELVQTLLER--GASIEHRDKKGFTPLILAATAGH 877
Query: 203 TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
+ L+ GAD+ A+ R +P A GR + V L+
Sbjct: 878 VGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELL 918
Score = 49.3 bits (116), Expect = 8e-06
Identities = 51/197 (25%), Positives = 81/197 (41%), Gaps = 17/197 (8%)
Query: 54 SDDSFYPFEDEEEHGVESAESVPEGV-------PESVPETATLLRAACANNVGLLRTLVR 106
+D+ + P + G E ++ G E ETA L A C + + L++
Sbjct: 497 NDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTL-ACCGGFLEVADFLIK 555
Query: 107 RGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAG 166
G +E T L+ A G ++ V L +V+ + G+TAL A + G
Sbjct: 556 AGADIELGCSTP------LMEAAQEGHLELVKYLLAAG-ANVHATTATGDTALTYACENG 608
Query: 167 HAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMS 226
H + + LL G DLE + G T LMKAA G ++ L+ GA+V+ +
Sbjct: 609 HTDVADVLLQ--AGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHT 666
Query: 227 PQEWATYTGRVDAVRLM 243
A G + V L+
Sbjct: 667 VLSLACAGGHLAVVELL 683
Score = 45.8 bits (107), Expect = 9e-05
Identities = 40/162 (24%), Positives = 66/162 (40%), Gaps = 34/162 (20%)
Query: 89 LLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDV 148
L+ A A +V + R L+ G + ++ + L +ACY G ++ V L E D
Sbjct: 371 LMEAGSAGHVEVARLLLENGAGINT--HSNEFKESALTLACYKGHLEMVRFLLEAG-ADQ 427
Query: 149 NWQDSEGNTALITAAQAGHAIITNYLLNYFP----------------------------- 179
+ E +TAL+ A GH + LL+
Sbjct: 428 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLI 487
Query: 180 --GLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHAR 219
G LE N G+T LM+AA +G + + L+ GA+++A+
Sbjct: 488 ERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQ 529
Score = 45.8 bits (107), Expect = 9e-05
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 3/97 (3%)
Query: 81 ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 140
ES L++AA A +V ++ L+ +G +V T N T L +AC G + VV L
Sbjct: 626 ESEGGRTPLMKAARAGHVCTVQFLISKGANVNRT--TANNDHTVLSLACAGGHL-AVVEL 682
Query: 141 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNY 177
D + +G+T LI AA+ GH + YLL+Y
Sbjct: 683 LLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDY 719
Score = 45.1 bits (105), Expect = 2e-04
Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 82 SVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALA 141
+V + L AA V +++ L+ G + ++ + G + L++A +G V L
Sbjct: 929 NVSDYTPLSLAASGGYVNIIKILLNAGAEIN-SRTGSKLGISPLMLAAMNGHTAAVKLLL 987
Query: 142 ECPHVDVNWQ-DSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 200
+ D+N Q ++ NTAL A G + + LL+ ++E R G T LM+AA
Sbjct: 988 DMGS-DINAQIETNRNTALTLACFQGRTEVVSLLLDR--KANVEHRAKTGLTPLMEAASG 1044
Query: 201 GRTDCIRALMLAGADVHA 218
G + R L+ GADV+A
Sbjct: 1045 GYAEVGRVLLDKGADVNA 1062
Score = 36.6 bits (83), Expect = 0.054
Identities = 42/161 (26%), Positives = 70/161 (43%), Gaps = 13/161 (8%)
Query: 88 TLLRAACANN-VGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAEC-PH 145
T L AC+ ++ L+ RG + E +D T L +A G+V+ + L
Sbjct: 901 TPLSLACSGGRQEVVELLLARGANKEHRNVSDY---TPLSLAASGGYVNIIKILLNAGAE 957
Query: 146 VDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLE---RRNAFGFTALMKAAMQGR 202
++ G + L+ AA GH LL+ ++ + RN TAL A QGR
Sbjct: 958 INSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRN----TALTLACFQGR 1013
Query: 203 TDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
T+ + L+ A+V R + G++P A G + R++
Sbjct: 1014 TEVVSLLLDRKANVEHR-AKTGLTPLMEAASGGYAEVGRVL 1053
Score = 33.5 bits (75), Expect = 0.46
Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 9/104 (8%)
Query: 79 VPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVV 138
VP S T+ AA + L+ RG ++ ++ G T L +A G +D V
Sbjct: 1065 VPSSRDTALTI--AADKGHYKFCELLIGRGAHIDVR---NKKGNTPLWLAANGGHLDVVQ 1119
Query: 139 ALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYL---LNYFP 179
L + DV+ D+ T L+ A + GH + YL +N FP
Sbjct: 1120 LLVQAG-ADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFP 1162
>gi|89363047 death-associated protein kinase 1 [Homo sapiens]
Length = 1430
Score = 58.9 bits (141), Expect = 1e-08
Identities = 51/160 (31%), Positives = 80/160 (50%), Gaps = 11/160 (6%)
Query: 86 TATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAE--C 143
T LL AA N+ +L+ L++RG ++ D+ G + A HG VDT+ L+E C
Sbjct: 380 TPPLLIAAGCGNIQILQLLIKRGSRIDVQ---DKGGSNAVYWAARHGHVDTLKFLSENKC 436
Query: 144 PHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRT 203
P +DV +D G AL AA+ GHA + L ++ +++ + T L AA G
Sbjct: 437 P-LDV--KDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEE--ETPLHCAAWHGYY 491
Query: 204 DCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
+AL AG +V+ ++ R G +P A+ G D V +
Sbjct: 492 SVAKALCEAGCNVNIKN-REGETPLLTASARGYHDIVECL 530
Score = 47.0 bits (110), Expect = 4e-05
Identities = 42/142 (29%), Positives = 63/142 (44%), Gaps = 7/142 (4%)
Query: 118 DRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNY 177
D+ T L A +HG+ AL E +VN ++ EG T L+TA+ G+ I L +
Sbjct: 475 DKEEETPLHCAAWHGYYSVAKALCEAG-CNVNIKNREGETPLLTASARGYHDIVECLAEH 533
Query: 178 FPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRV 237
G DL + G AL A + + + I+ L+ G V +D R G +P A G +
Sbjct: 534 --GADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQD-RHGNTPLHVACKDGNM 590
Query: 238 DAVRLMQRLLERPCPEQFWEKY 259
++ L E C KY
Sbjct: 591 P---IVVALCEANCNLDISNKY 609
Score = 36.6 bits (83), Expect = 0.054
Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Query: 100 LLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTAL 159
+++TL+ +G V+ DR+G T L VAC G + VVAL E + +++ + G T L
Sbjct: 559 VIKTLLSQGCFVDYQ---DRHGNTPLHVACKDGNMPIVVALCEA-NCNLDISNKYGRTPL 614
Query: 160 ITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTA 193
AA G + YL G +E G TA
Sbjct: 615 HLAANNGILDVVRYLC--LMGASVEALTTDGKTA 646
>gi|17864094 feminization 1 homolog a [Homo sapiens]
Length = 617
Score = 58.2 bits (139), Expect = 2e-08
Identities = 46/160 (28%), Positives = 76/160 (47%), Gaps = 8/160 (5%)
Query: 81 ESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVAL 140
E++ L A+ A ++ ++++L+ G SV T+ T L AC+ G ++ V L
Sbjct: 79 ETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNS---TPLRAACFDGHLEIVKYL 135
Query: 141 AECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQ 200
E D+ + G+T L+ + GH I YLL G D+ R++ G TAL A
Sbjct: 136 VE-HKADLEVSNRHGHTCLMISCYKGHKEIAQYLLE--KGADVNRKSVKGNTALHDCAES 192
Query: 201 GRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAV 240
G D ++ L++ A + GM+P A+ TG + V
Sbjct: 193 GSLDIMKMLLMYCAKM--EKDGYGMTPLLSASVTGHTNIV 230
Score = 40.8 bits (94), Expect = 0.003
Identities = 45/180 (25%), Positives = 77/180 (42%), Gaps = 10/180 (5%)
Query: 70 ESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRR-GVSVEEAQETDRNGRT----- 123
+S E V + E LL AA ++ ++ L+ + S+E + +G T
Sbjct: 26 KSKEEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAP 85
Query: 124 GLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDL 183
L A G + V +L VN +T L A GH I YL+ + DL
Sbjct: 86 PLWAASAAGHLKVVQSLLN-HGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEH--KADL 142
Query: 184 ERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLM 243
E N G T LM + +G + + L+ GADV+ + + + + A +G +D ++++
Sbjct: 143 EVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAE-SGSLDIMKML 201
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,412,079
Number of Sequences: 37866
Number of extensions: 1316552
Number of successful extensions: 15053
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 210
Number of HSP's successfully gapped in prelim test: 497
Number of HSP's that attempted gapping in prelim test: 12123
Number of HSP's gapped (non-prelim): 2884
length of query: 494
length of database: 18,247,518
effective HSP length: 106
effective length of query: 388
effective length of database: 14,233,722
effective search space: 5522684136
effective search space used: 5522684136
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.