Guide to the Human Genome
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Search of human proteins with 116284382

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116284382 G protein-coupled bile acid receptor 1 [Homo
sapiens]
         (330 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116284382 G protein-coupled bile acid receptor 1 [Homo sapiens]    664   0.0  
gi|116284384 G protein-coupled bile acid receptor 1 [Homo sapiens]    664   0.0  
gi|24850109 G protein-coupled bile acid receptor 1 [Homo sapiens]     664   0.0  
gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo sa...    68   1e-11
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]            57   2e-08
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]             57   2e-08
gi|4501951 adenosine A2b receptor [Homo sapiens]                       56   4e-08
gi|13540517 endothelial differentiation, sphingolipid G-protein-...    55   9e-08
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]                54   2e-07
gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]            49   5e-06
gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]            49   5e-06
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi...    49   8e-06
gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]           48   1e-05
gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]           48   1e-05
gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]           48   1e-05
gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]           48   1e-05
gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]            48   1e-05
gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]          48   1e-05
gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]           48   1e-05
gi|36951034 G protein-coupled receptor 78 [Homo sapiens]               48   1e-05
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]          47   2e-05
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]          47   2e-05
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]          47   2e-05
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]          47   2e-05
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]          47   2e-05
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]          47   2e-05
gi|4557865 somatostatin receptor 5 [Homo sapiens]                      45   7e-05
gi|9789897 leukotriene B4 receptor 2 [Homo sapiens]                    45   7e-05
gi|223633986 trace amine associated receptor 5 [Homo sapiens]          45   7e-05
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]                 45   9e-05

>gi|116284382 G protein-coupled bile acid receptor 1 [Homo sapiens]
          Length = 330

 Score =  664 bits (1712), Expect = 0.0
 Identities = 330/330 (100%), Positives = 330/330 (100%)

Query: 1   MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA 60
           MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
Sbjct: 1   MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA 60

Query: 61  GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP 120
           GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
Sbjct: 61  GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP 120

Query: 121 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA 180
           PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
Sbjct: 121 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA 180

Query: 181 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY 240
           AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
Sbjct: 181 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY 240

Query: 241 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ 300
           VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
Sbjct: 241 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ 300

Query: 301 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN 330
           GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
Sbjct: 301 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN 330


>gi|116284384 G protein-coupled bile acid receptor 1 [Homo sapiens]
          Length = 330

 Score =  664 bits (1712), Expect = 0.0
 Identities = 330/330 (100%), Positives = 330/330 (100%)

Query: 1   MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA 60
           MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
Sbjct: 1   MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA 60

Query: 61  GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP 120
           GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
Sbjct: 61  GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP 120

Query: 121 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA 180
           PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
Sbjct: 121 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA 180

Query: 181 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY 240
           AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
Sbjct: 181 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY 240

Query: 241 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ 300
           VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
Sbjct: 241 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ 300

Query: 301 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN 330
           GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
Sbjct: 301 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN 330


>gi|24850109 G protein-coupled bile acid receptor 1 [Homo sapiens]
          Length = 330

 Score =  664 bits (1712), Expect = 0.0
 Identities = 330/330 (100%), Positives = 330/330 (100%)

Query: 1   MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA 60
           MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
Sbjct: 1   MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA 60

Query: 61  GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP 120
           GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
Sbjct: 61  GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP 120

Query: 121 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA 180
           PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
Sbjct: 121 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA 180

Query: 181 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY 240
           AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
Sbjct: 181 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY 240

Query: 241 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ 300
           VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
Sbjct: 241 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ 300

Query: 301 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN 330
           GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
Sbjct: 301 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN 330


>gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo
           sapiens]
          Length = 384

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 81/268 (30%), Positives = 115/268 (42%), Gaps = 25/268 (9%)

Query: 16  GAL-GLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLLTGLALPTLPGL 74
           GAL GLS+A + L++  NLL+   I    R R     C  +++ L+ LLTG A      L
Sbjct: 47  GALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCL-VNITLSDLLTGAAY-LANVL 104

Query: 75  WNQSRRGYWSCLLVYLAPNFSFLSLLAN---LLLVHGERYMAVLRPLQPPGSIRLALL-- 129
            + +R    +    +L     F +L A+   LL   GER+  ++RP+   G+ + + +  
Sbjct: 105 LSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYG 164

Query: 130 ---LTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGAAAFLSV 186
              L W    L   LP LGWN       CSS  + P   LY + Y L    + A      
Sbjct: 165 FIGLCWLLAALLGMLPLLGWNCLCAFDRCSS--LLP---LYSKRYILFCLVIFAG----- 214

Query: 187 RVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPYVATLLL 246
            VLAT       I RL +A  +  P   AR    R  +     +L F +CWGP    LL 
Sbjct: 215 -VLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLA 273

Query: 247 SVLA---YEQRPPLGPGTLLSLLSLGSA 271
            V     + Q    G   +L+L  L SA
Sbjct: 274 DVFGSNLWAQEYLRGMDWILALAVLNSA 301


>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
          Length = 397

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 65/264 (24%), Positives = 115/264 (43%), Gaps = 38/264 (14%)

Query: 1   MTPNSTGE---VPSPIPKGALGLSLALASLIITA-NLLLALGIAWDRRLRSPPAGCFFLS 56
           M PN T     + S   K  + + LA+  LI  A N+++ L +  +RRLR+    CF +S
Sbjct: 1   MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVS 59

Query: 57  LLLAGLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLA---NLLLVHGERYMA 113
           L +  LL GL +     ++  S +  +  +   +  +   +   A   NL ++  +RY A
Sbjct: 60  LAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCA 119

Query: 114 VLRPLQ-----PPGSIRLALLLTWAGPLLFASLPA-LGW---NHWTPGANCSSQAIFPAP 164
           V+ PL+      P  + ++L+L W   +  + L   LGW   N  + G + +S+      
Sbjct: 120 VMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVN 179

Query: 165 YLYLEVYGLLLPAVGAAAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQAR 224
               EVYGL+   V    +L + ++   + ++         V RD+   +    +W+ A 
Sbjct: 180 ----EVYGLVDGLV--TFYLPLLIMCITYYRI-------FKVARDQAKRINHISSWKAAT 226

Query: 225 AQ--------AGAMLLFGLCWGPY 240
            +        A  M  F +CW PY
Sbjct: 227 IREHKATVTLAAVMGAFIICWFPY 250


>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
          Length = 359

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 65/264 (24%), Positives = 115/264 (43%), Gaps = 38/264 (14%)

Query: 1   MTPNSTGE---VPSPIPKGALGLSLALASLIITA-NLLLALGIAWDRRLRSPPAGCFFLS 56
           M PN T     + S   K  + + LA+  LI  A N+++ L +  +RRLR+    CF +S
Sbjct: 1   MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVS 59

Query: 57  LLLAGLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLA---NLLLVHGERYMA 113
           L +  LL GL +     ++  S +  +  +   +  +   +   A   NL ++  +RY A
Sbjct: 60  LAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCA 119

Query: 114 VLRPLQ-----PPGSIRLALLLTWAGPLLFASLPA-LGW---NHWTPGANCSSQAIFPAP 164
           V+ PL+      P  + ++L+L W   +  + L   LGW   N  + G + +S+      
Sbjct: 120 VMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVN 179

Query: 165 YLYLEVYGLLLPAVGAAAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQAR 224
               EVYGL+   V    +L + ++   + ++         V RD+   +    +W+ A 
Sbjct: 180 ----EVYGLVDGLV--TFYLPLLIMCITYYRI-------FKVARDQAKRINHISSWKAAT 226

Query: 225 AQ--------AGAMLLFGLCWGPY 240
            +        A  M  F +CW PY
Sbjct: 227 IREHKATVTLAAVMGAFIICWFPY 250


>gi|4501951 adenosine A2b receptor [Homo sapiens]
          Length = 332

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 67/298 (22%), Positives = 119/298 (39%), Gaps = 35/298 (11%)

Query: 18  LGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLLTGL-ALPTLPGLWN 76
           + L L +A+L +  N+L+   +     L++P    F +SL  A +  GL A+P    +  
Sbjct: 11  VALELVIAALSVAGNVLVCAAVGTANTLQTP-TNYFLVSLAAADVAVGLFAIPFAITISL 69

Query: 77  QSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQPPGSI-----RLALLLT 131
                ++ CL +         S + +LL V  +RY+A+  PL+    +     R  + + 
Sbjct: 70  GFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVL 129

Query: 132 WAGPLLFASLPALGWNHWTPGAN------------------CSSQAIFPAPYL-YLEVYG 172
           W         P LGWN      N                  C  + + P  Y+ Y   +G
Sbjct: 130 WVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFG 189

Query: 173 LLLPAVGAAAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLL 232
            +LP +     + +++   A RQLQ    ++ +      + L R +    A++ A  + +
Sbjct: 190 CVLPPLLIMLVIYIKIFLVACRQLQRTELMDHS-----RTTLQREI--HAAKSLAMIVGI 242

Query: 233 FGLCWGPYVATLLLSVL--AYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYT 288
           F LCW P  A   +++   A  +  P     +  LLS  ++    +  A    D RYT
Sbjct: 243 FALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT 300


>gi|13540517 endothelial differentiation, sphingolipid
           G-protein-coupled receptor, 8 [Homo sapiens]
          Length = 398

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 73/247 (29%), Positives = 96/247 (38%), Gaps = 35/247 (14%)

Query: 22  LALASLIITANLLLALGIAWDRRLRSPP---AGCFFLSLLLAG-------LLTG-LALPT 70
           LA+ + I+  NL + L +    R  +P     G   LS LLAG       LL+G L L  
Sbjct: 44  LAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKL 103

Query: 71  LPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLR----PLQPPGSIRL 126
            P LW     G      V++A   S LSLLA  L    ER + + R    P+   G    
Sbjct: 104 SPALWFAREGG------VFVALTASVLSLLAIAL----ERSLTMARRGPAPVSSRGRTLA 153

Query: 127 ALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGL--LLPAVG---AA 181
                W   LL   LPALGWN       CS+  + P   LY + Y L  +L  VG   A 
Sbjct: 154 MAAAAWGVSLLLGLLPALGWNCLGRLDACST--VLP---LYAKAYVLFCVLAFVGILAAI 208

Query: 182 AFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPYV 241
             L  R+        + +             A  +  +    R  +  +L F  CWGP  
Sbjct: 209 CALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLF 268

Query: 242 ATLLLSV 248
             LLL V
Sbjct: 269 LLLLLDV 275


>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
          Length = 408

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 88/328 (26%), Positives = 127/328 (38%), Gaps = 58/328 (17%)

Query: 2   TPNSTGEVPSPIPKGALGLSLALASLI-ITANLLLALGIAWDRRLRSPPAGCFFLSLLLA 60
           T N++G    P      G  LALA L  +  NLL+ + IAW  RL++     F  SL  A
Sbjct: 24  TANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIVAIAWTPRLQT-MTNVFVTSLAAA 82

Query: 61  GLLTGLALPTLPGLWNQSRRGYW-----SCLLVYLAPNFSFLSLLANLLLVHGERYMAVL 115
            L+ GL +  +P     +  G+W      C L          + +  L  +  +RY+AV 
Sbjct: 83  DLVMGLLV--VPPAATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAVT 140

Query: 116 RPLQPPGSI-----RLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAP----YL 166
            PL+    +     R A++L W      +  P +    W  GA+  +Q     P    + 
Sbjct: 141 NPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMS-QWWRVGADAEAQRCHSNPRCCAFA 199

Query: 167 YLEVYGLLLPAVG------AAAFLSVRVLATAHRQLQDI-CRLERAVCRDEPSA------ 213
               Y LL  +V          F+  RV   A RQL+ +   L R    + P A      
Sbjct: 200 SNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRGELGRFPPEESPPAPSRSLA 259

Query: 214 -------------------LARALTWRQARAQAGAMLLFG---LCWGPYVATLLLSVLAY 251
                               AR L  R+ RA     L+ G   LCW P+    L +VL  
Sbjct: 260 PAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGTFTLCWLPF---FLANVLRA 316

Query: 252 EQRPPLGPG-TLLSLLSLGSASAAAVPV 278
              P L PG   L+L  LG A++A  P+
Sbjct: 317 LGGPSLVPGPAFLALNWLGYANSAFNPL 344


>gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]
          Length = 364

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 74/300 (24%), Positives = 126/300 (42%), Gaps = 44/300 (14%)

Query: 13  IPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFL--SLLLAGLLTGLA--- 67
           + K  +GL + +   I+ ANLL+ + I  +RR   P    ++L  +L  A    GLA   
Sbjct: 48  VSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFP---IYYLMANLAAADFFAGLAYFY 104

Query: 68  --LPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLR-PLQPPGSI 124
               T P   N  R    + LL     + S  + +ANLL +  ER++ V R  L    S 
Sbjct: 105 LMFNTGP---NTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSN 161

Query: 125 R---LALLLTWAGPLLFASLPALGWNHWTPGANCSSQA-IFPAPYL-YLEVYGLLLPAVG 179
           R   + +++ W   ++  ++P++GWN      NCS+ A ++   YL +  ++ L+   V 
Sbjct: 162 RRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVV- 220

Query: 180 AAAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGP 239
               L   +     ++   + R      R+  + ++   T        GA   F +CW P
Sbjct: 221 -MVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKT---VVIVLGA---FIICWTP 273

Query: 240 YVATLLL-------SVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWR 292
            +  LLL        VLAYE+            L L   ++A  P+     D+  +A +R
Sbjct: 274 GLVLLLLDVCCPQCDVLAYEK----------FFLLLAEFNSAMNPIIYSYRDKEMSATFR 323


>gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]
          Length = 364

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 74/300 (24%), Positives = 126/300 (42%), Gaps = 44/300 (14%)

Query: 13  IPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFL--SLLLAGLLTGLA--- 67
           + K  +GL + +   I+ ANLL+ + I  +RR   P    ++L  +L  A    GLA   
Sbjct: 48  VSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFP---IYYLMANLAAADFFAGLAYFY 104

Query: 68  --LPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLR-PLQPPGSI 124
               T P   N  R    + LL     + S  + +ANLL +  ER++ V R  L    S 
Sbjct: 105 LMFNTGP---NTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSN 161

Query: 125 R---LALLLTWAGPLLFASLPALGWNHWTPGANCSSQA-IFPAPYL-YLEVYGLLLPAVG 179
           R   + +++ W   ++  ++P++GWN      NCS+ A ++   YL +  ++ L+   V 
Sbjct: 162 RRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVV- 220

Query: 180 AAAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGP 239
               L   +     ++   + R      R+  + ++   T        GA   F +CW P
Sbjct: 221 -MVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKT---VVIVLGA---FIICWTP 273

Query: 240 YVATLLL-------SVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWR 292
            +  LLL        VLAYE+            L L   ++A  P+     D+  +A +R
Sbjct: 274 GLVLLLLDVCCPQCDVLAYEK----------FFLLLAEFNSAMNPIIYSYRDKEMSATFR 323


>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
           sapiens]
          Length = 440

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 74/280 (26%), Positives = 111/280 (39%), Gaps = 41/280 (14%)

Query: 2   TPNST---GEVPSPIPKGALGLSLALA---SLIITANLLLALGIAWDRRLRSPPAGCFFL 55
           T NST   G  P   P G+  ++ AL    +L   AN LL   I     LR+  +  F +
Sbjct: 8   TANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT-SNFFLV 66

Query: 56  SLLLAGLLTGLALPTLPGLWNQSRRGYWS-----CLLVYLAPNFSFLSLLANLLLVHGER 110
           SL  + L+ GL +  +P     +  G W      CLL          + + NL L+  +R
Sbjct: 67  SLFTSDLMVGLVV--MPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDR 124

Query: 111 YMAVLRPLQ-----PPGSIRLALLLTWAGPLLFASLP-ALGWN---HWTPGANCSSQAIF 161
           Y+ +L PL+      P      +L  W+   L + LP  LGW+   H  P      + + 
Sbjct: 125 YLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLA 184

Query: 162 PAPYLYLEVYGL--LLPAVGAAAFLSVRVLATAHRQLQDICRLERAVCRDE--------- 210
             P++ L   GL   LP+ GA  F   R+L  A +Q   +  L   +             
Sbjct: 185 SLPFV-LVASGLTFFLPS-GAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRT 242

Query: 211 -----PSALARALTWRQARAQAGAMLLFGLCWGPYVATLL 245
                 SA +R L  + +R    A L  G+  G +  T L
Sbjct: 243 PRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWL 282


>gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 71/288 (24%), Positives = 121/288 (42%), Gaps = 23/288 (7%)

Query: 20  LSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLL-TGLALPTLPGLWNQS 78
           LSL L +  +  NLL+   I   R LR  P+  F  SL +A LL + + + +        
Sbjct: 122 LSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFH 181

Query: 79  RRGYWSCLLVYL-APNFSFLSLLANLLLVHGERYMAVLRPL------QPPGSIRLALLLT 131
           R+   +  L  L     SF + + +L L   +RY+++ RPL        P ++ +A  L 
Sbjct: 182 RKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAV-VAFCLM 240

Query: 132 WAGPLLFASLPALGWNHWTPGANCSSQAIFP---APYLYLEV---YGLLLPAVGAAAFLS 185
           W   ++ A LP LGWN     + CS   IFP     YL   +     LLL  V A  ++ 
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSD--IFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298

Query: 186 VRVLATAHRQLQDICRLERAVCRDEPSAL------ARALTWRQARAQAGAMLLFGLCWGP 239
            +  + A R +Q   +    +   E   +         +  R A+     +++  +CWGP
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358

Query: 240 YVATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRY 287
            +A ++  V     +         S+L L +++   +  A+   D R+
Sbjct: 359 LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRH 406


>gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 71/288 (24%), Positives = 121/288 (42%), Gaps = 23/288 (7%)

Query: 20  LSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLL-TGLALPTLPGLWNQS 78
           LSL L +  +  NLL+   I   R LR  P+  F  SL +A LL + + + +        
Sbjct: 122 LSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFH 181

Query: 79  RRGYWSCLLVYL-APNFSFLSLLANLLLVHGERYMAVLRPL------QPPGSIRLALLLT 131
           R+   +  L  L     SF + + +L L   +RY+++ RPL        P ++ +A  L 
Sbjct: 182 RKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAV-VAFCLM 240

Query: 132 WAGPLLFASLPALGWNHWTPGANCSSQAIFP---APYLYLEV---YGLLLPAVGAAAFLS 185
           W   ++ A LP LGWN     + CS   IFP     YL   +     LLL  V A  ++ 
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSD--IFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298

Query: 186 VRVLATAHRQLQDICRLERAVCRDEPSAL------ARALTWRQARAQAGAMLLFGLCWGP 239
            +  + A R +Q   +    +   E   +         +  R A+     +++  +CWGP
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358

Query: 240 YVATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRY 287
            +A ++  V     +         S+L L +++   +  A+   D R+
Sbjct: 359 LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRH 406


>gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 71/288 (24%), Positives = 121/288 (42%), Gaps = 23/288 (7%)

Query: 20  LSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLL-TGLALPTLPGLWNQS 78
           LSL L +  +  NLL+   I   R LR  P+  F  SL +A LL + + + +        
Sbjct: 122 LSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFH 181

Query: 79  RRGYWSCLLVYL-APNFSFLSLLANLLLVHGERYMAVLRPL------QPPGSIRLALLLT 131
           R+   +  L  L     SF + + +L L   +RY+++ RPL        P ++ +A  L 
Sbjct: 182 RKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAV-VAFCLM 240

Query: 132 WAGPLLFASLPALGWNHWTPGANCSSQAIFP---APYLYLEV---YGLLLPAVGAAAFLS 185
           W   ++ A LP LGWN     + CS   IFP     YL   +     LLL  V A  ++ 
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSD--IFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298

Query: 186 VRVLATAHRQLQDICRLERAVCRDEPSAL------ARALTWRQARAQAGAMLLFGLCWGP 239
            +  + A R +Q   +    +   E   +         +  R A+     +++  +CWGP
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358

Query: 240 YVATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRY 287
            +A ++  V     +         S+L L +++   +  A+   D R+
Sbjct: 359 LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRH 406


>gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 71/288 (24%), Positives = 121/288 (42%), Gaps = 23/288 (7%)

Query: 20  LSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLL-TGLALPTLPGLWNQS 78
           LSL L +  +  NLL+   I   R LR  P+  F  SL +A LL + + + +        
Sbjct: 122 LSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFH 181

Query: 79  RRGYWSCLLVYL-APNFSFLSLLANLLLVHGERYMAVLRPL------QPPGSIRLALLLT 131
           R+   +  L  L     SF + + +L L   +RY+++ RPL        P ++ +A  L 
Sbjct: 182 RKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAV-VAFCLM 240

Query: 132 WAGPLLFASLPALGWNHWTPGANCSSQAIFP---APYLYLEV---YGLLLPAVGAAAFLS 185
           W   ++ A LP LGWN     + CS   IFP     YL   +     LLL  V A  ++ 
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSD--IFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298

Query: 186 VRVLATAHRQLQDICRLERAVCRDEPSAL------ARALTWRQARAQAGAMLLFGLCWGP 239
            +  + A R +Q   +    +   E   +         +  R A+     +++  +CWGP
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358

Query: 240 YVATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRY 287
            +A ++  V     +         S+L L +++   +  A+   D R+
Sbjct: 359 LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRH 406


>gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 71/288 (24%), Positives = 121/288 (42%), Gaps = 23/288 (7%)

Query: 20  LSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLL-TGLALPTLPGLWNQS 78
           LSL L +  +  NLL+   I   R LR  P+  F  SL +A LL + + + +        
Sbjct: 122 LSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFH 181

Query: 79  RRGYWSCLLVYL-APNFSFLSLLANLLLVHGERYMAVLRPL------QPPGSIRLALLLT 131
           R+   +  L  L     SF + + +L L   +RY+++ RPL        P ++ +A  L 
Sbjct: 182 RKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAV-VAFCLM 240

Query: 132 WAGPLLFASLPALGWNHWTPGANCSSQAIFP---APYLYLEV---YGLLLPAVGAAAFLS 185
           W   ++ A LP LGWN     + CS   IFP     YL   +     LLL  V A  ++ 
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSD--IFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298

Query: 186 VRVLATAHRQLQDICRLERAVCRDEPSAL------ARALTWRQARAQAGAMLLFGLCWGP 239
            +  + A R +Q   +    +   E   +         +  R A+     +++  +CWGP
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358

Query: 240 YVATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRY 287
            +A ++  V     +         S+L L +++   +  A+   D R+
Sbjct: 359 LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRH 406


>gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]
          Length = 382

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 66/236 (27%), Positives = 102/236 (43%), Gaps = 17/236 (7%)

Query: 22  LALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLLTGLALPTLPGLWNQSRRG 81
           + +   II  N+ + L I W  +    P   F  +L L+ LL G+A  T   L + +   
Sbjct: 53  ILICCFIILENIFVLLTI-WKTKKFHRPMYYFIGNLALSDLLAGVAY-TANLLLSGATTY 110

Query: 82  YWSCLLVYLAPNFSFLSLLAN---LLLVHGERYMAVLRPLQPPGS--IRLALLLT--WAG 134
             +    +L     F++L A+   LL +  ERY+ +L+     GS   RL LL++  W  
Sbjct: 111 KLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVI 170

Query: 135 PLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGAAAFLSVRVLATAHR 194
            L+   LP +GWN  +  ++CS+  + P   LY + Y L    V     LS+ +L     
Sbjct: 171 SLILGGLPIMGWNCISALSSCST--VLP---LYHKHYILFCTTVFTLLLLSIVILYCRIY 225

Query: 195 QLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLL--FGLCWGPYVATLLLSV 248
            L    R  R   R   S  +R+     A  +   ++L  F  CW P    LLL V
Sbjct: 226 SLVR-TRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDV 280


>gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]
          Length = 439

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 71/288 (24%), Positives = 121/288 (42%), Gaps = 23/288 (7%)

Query: 20  LSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLL-TGLALPTLPGLWNQS 78
           LSL L +  +  NLL+   I   R LR  P+  F  SL +A LL + + + +        
Sbjct: 89  LSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFH 148

Query: 79  RRGYWSCLLVYL-APNFSFLSLLANLLLVHGERYMAVLRPL------QPPGSIRLALLLT 131
           R+   +  L  L     SF + + +L L   +RY+++ RPL        P ++ +A  L 
Sbjct: 149 RKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAV-VAFCLM 207

Query: 132 WAGPLLFASLPALGWNHWTPGANCSSQAIFP---APYLYLEV---YGLLLPAVGAAAFLS 185
           W   ++ A LP LGWN     + CS   IFP     YL   +     LLL  V A  ++ 
Sbjct: 208 WTIAIVIAVLPLLGWNCEKLQSVCSD--IFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 265

Query: 186 VRVLATAHRQLQDICRLERAVCRDEPSAL------ARALTWRQARAQAGAMLLFGLCWGP 239
            +  + A R +Q   +    +   E   +         +  R A+     +++  +CWGP
Sbjct: 266 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 325

Query: 240 YVATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRY 287
            +A ++  V     +         S+L L +++   +  A+   D R+
Sbjct: 326 LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRH 373


>gi|36951034 G protein-coupled receptor 78 [Homo sapiens]
          Length = 363

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 67/260 (25%), Positives = 114/260 (43%), Gaps = 28/260 (10%)

Query: 19  GLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLL-TGLALP-TLPGLWN 76
           GL + + ++ + +N L+ L  A+   LR+  +G   ++L L  LL   L +P TL G+  
Sbjct: 10  GLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTLLGVMR 69

Query: 77  -QSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQPPGSIR-----LALLL 130
            ++     +C ++     F   +   ++  +  ++++AV  PL+  G +R     L L  
Sbjct: 70  GRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPRYAGLLLGC 129

Query: 131 TWAGPLLFASLPALG--WNHWTPG-ANCS-------SQAIFPAPYLYLEVYGLLLP-AVG 179
            W   L F+   ALG  W  ++   A+CS        +  F A    L   G +LP AV 
Sbjct: 130 AWGQSLAFSGA-ALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHAVGFVLPLAVL 188

Query: 180 AAAFLSVRVLATAHRQLQDICRLER-AVCRD-EPSALARALTWRQARAQAG------AML 231
               L V  +A  H Q  D   ++  A+  D  PS   R L  ++ R          A+ 
Sbjct: 189 CLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHRATRKIGIAIA 248

Query: 232 LFGLCWGPYVATLLLSVLAY 251
            F +C+ PYV T L  ++ +
Sbjct: 249 TFLICFAPYVMTRLAELVPF 268


>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
          Length = 359

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 63/252 (25%), Positives = 99/252 (39%), Gaps = 40/252 (15%)

Query: 27  LIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLLTGL------ALPTLPGLWNQSRR 80
           + I  NLL+ + + WDR+LR      F +SL  A LL  +      A+  +  +W     
Sbjct: 32  MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIY--- 88

Query: 81  GYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAV-LRPL---QPPGSIRLALLL--TWAG 134
           G   CL+          + + +L  +  +RY A+  +PL        +R+AL+L   W  
Sbjct: 89  GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVI 148

Query: 135 PLLFASLPAL-GWNH-----------WTPGANCSSQAIFPA--PY-LYLEVYGLLLPAVG 179
           P   + LP + GWN+           +   +N S+  +F    PY +   V    +P + 
Sbjct: 149 PTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN-STYCVFMVNKPYAITCSVVAFYIPFL- 206

Query: 180 AAAFLSVRVLATAHRQLQDICRLERAVCRDE--PSALARALTWRQARAQAGAMLL----- 232
                  R+  TA      I  L+RA    E  P +  +  T R       A  L     
Sbjct: 207 LMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMG 266

Query: 233 -FGLCWGPYVAT 243
            F LCW P+  T
Sbjct: 267 CFCLCWAPFFVT 278


>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
          Length = 428

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 63/252 (25%), Positives = 99/252 (39%), Gaps = 40/252 (15%)

Query: 27  LIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLLTGL------ALPTLPGLWNQSRR 80
           + I  NLL+ + + WDR+LR      F +SL  A LL  +      A+  +  +W     
Sbjct: 32  MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIY--- 88

Query: 81  GYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAV-LRPL---QPPGSIRLALLL--TWAG 134
           G   CL+          + + +L  +  +RY A+  +PL        +R+AL+L   W  
Sbjct: 89  GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVI 148

Query: 135 PLLFASLPAL-GWNH-----------WTPGANCSSQAIFPA--PY-LYLEVYGLLLPAVG 179
           P   + LP + GWN+           +   +N S+  +F    PY +   V    +P + 
Sbjct: 149 PTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN-STYCVFMVNKPYAITCSVVAFYIPFL- 206

Query: 180 AAAFLSVRVLATAHRQLQDICRLERAVCRDE--PSALARALTWRQARAQAGAMLL----- 232
                  R+  TA      I  L+RA    E  P +  +  T R       A  L     
Sbjct: 207 LMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMG 266

Query: 233 -FGLCWGPYVAT 243
            F LCW P+  T
Sbjct: 267 CFCLCWAPFFVT 278


>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
          Length = 360

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 63/252 (25%), Positives = 99/252 (39%), Gaps = 40/252 (15%)

Query: 27  LIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLLTGL------ALPTLPGLWNQSRR 80
           + I  NLL+ + + WDR+LR      F +SL  A LL  +      A+  +  +W     
Sbjct: 32  MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIY--- 88

Query: 81  GYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAV-LRPL---QPPGSIRLALLL--TWAG 134
           G   CL+          + + +L  +  +RY A+  +PL        +R+AL+L   W  
Sbjct: 89  GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVI 148

Query: 135 PLLFASLPAL-GWNH-----------WTPGANCSSQAIFPA--PY-LYLEVYGLLLPAVG 179
           P   + LP + GWN+           +   +N S+  +F    PY +   V    +P + 
Sbjct: 149 PTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN-STYCVFMVNKPYAITCSVVAFYIPFL- 206

Query: 180 AAAFLSVRVLATAHRQLQDICRLERAVCRDE--PSALARALTWRQARAQAGAMLL----- 232
                  R+  TA      I  L+RA    E  P +  +  T R       A  L     
Sbjct: 207 LMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMG 266

Query: 233 -FGLCWGPYVAT 243
            F LCW P+  T
Sbjct: 267 CFCLCWAPFFVT 278


>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
          Length = 387

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 63/252 (25%), Positives = 99/252 (39%), Gaps = 40/252 (15%)

Query: 27  LIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLLTGL------ALPTLPGLWNQSRR 80
           + I  NLL+ + + WDR+LR      F +SL  A LL  +      A+  +  +W     
Sbjct: 32  MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIY--- 88

Query: 81  GYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAV-LRPL---QPPGSIRLALLL--TWAG 134
           G   CL+          + + +L  +  +RY A+  +PL        +R+AL+L   W  
Sbjct: 89  GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVI 148

Query: 135 PLLFASLPAL-GWNH-----------WTPGANCSSQAIFPA--PY-LYLEVYGLLLPAVG 179
           P   + LP + GWN+           +   +N S+  +F    PY +   V    +P + 
Sbjct: 149 PTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN-STYCVFMVNKPYAITCSVVAFYIPFL- 206

Query: 180 AAAFLSVRVLATAHRQLQDICRLERAVCRDE--PSALARALTWRQARAQAGAMLL----- 232
                  R+  TA      I  L+RA    E  P +  +  T R       A  L     
Sbjct: 207 LMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMG 266

Query: 233 -FGLCWGPYVAT 243
            F LCW P+  T
Sbjct: 267 CFCLCWAPFFVT 278


>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
          Length = 378

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 63/252 (25%), Positives = 99/252 (39%), Gaps = 40/252 (15%)

Query: 27  LIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLLTGL------ALPTLPGLWNQSRR 80
           + I  NLL+ + + WDR+LR      F +SL  A LL  +      A+  +  +W     
Sbjct: 32  MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIY--- 88

Query: 81  GYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAV-LRPL---QPPGSIRLALLL--TWAG 134
           G   CL+          + + +L  +  +RY A+  +PL        +R+AL+L   W  
Sbjct: 89  GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVI 148

Query: 135 PLLFASLPAL-GWNH-----------WTPGANCSSQAIFPA--PY-LYLEVYGLLLPAVG 179
           P   + LP + GWN+           +   +N S+  +F    PY +   V    +P + 
Sbjct: 149 PTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN-STYCVFMVNKPYAITCSVVAFYIPFL- 206

Query: 180 AAAFLSVRVLATAHRQLQDICRLERAVCRDE--PSALARALTWRQARAQAGAMLL----- 232
                  R+  TA      I  L+RA    E  P +  +  T R       A  L     
Sbjct: 207 LMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMG 266

Query: 233 -FGLCWGPYVAT 243
            F LCW P+  T
Sbjct: 267 CFCLCWAPFFVT 278


>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
          Length = 388

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 63/252 (25%), Positives = 99/252 (39%), Gaps = 40/252 (15%)

Query: 27  LIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLLTGL------ALPTLPGLWNQSRR 80
           + I  NLL+ + + WDR+LR      F +SL  A LL  +      A+  +  +W     
Sbjct: 32  MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIY--- 88

Query: 81  GYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAV-LRPL---QPPGSIRLALLL--TWAG 134
           G   CL+          + + +L  +  +RY A+  +PL        +R+AL+L   W  
Sbjct: 89  GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVI 148

Query: 135 PLLFASLPAL-GWNH-----------WTPGANCSSQAIFPA--PY-LYLEVYGLLLPAVG 179
           P   + LP + GWN+           +   +N S+  +F    PY +   V    +P + 
Sbjct: 149 PTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN-STYCVFMVNKPYAITCSVVAFYIPFL- 206

Query: 180 AAAFLSVRVLATAHRQLQDICRLERAVCRDE--PSALARALTWRQARAQAGAMLL----- 232
                  R+  TA      I  L+RA    E  P +  +  T R       A  L     
Sbjct: 207 LMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMG 266

Query: 233 -FGLCWGPYVAT 243
            F LCW P+  T
Sbjct: 267 CFCLCWAPFFVT 278


>gi|4557865 somatostatin receptor 5 [Homo sapiens]
          Length = 364

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 64/272 (23%), Positives = 108/272 (39%), Gaps = 25/272 (9%)

Query: 53  FFLSLLLAGLLTGLALPTLPGLWNQSRRGYWS-----CLLVYLAPNFSFLSLLANLLLVH 107
           + L+L +A +L  L LP L     Q+   +W      C LV      +  + +  L ++ 
Sbjct: 78  YILNLAVADVLYMLGLPFLA---TQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMS 134

Query: 108 GERYMAVLRPLQP-----PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFP 162
            +RY+AV+ PL       P   +LA    W   L   SLP L +     G  C+  A +P
Sbjct: 135 VDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCM-SLPLLVFADVQEGGTCN--ASWP 191

Query: 163 APY-LYLEVYGLLLPAVGAAAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWR 221
            P  L+  V+ +    +G  A L V  L      L  + ++  A  R     + R    +
Sbjct: 192 EPVGLWGAVFIIYTAVLGFFAPLLVICLC----YLLIVVKVRAAGVR--VGCVRRRSERK 245

Query: 222 QARAQAGAMLLFGLCWGPYVATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMG 281
             R     +L+F  CW P+    ++++     + P   G    ++ L  A++ A PV  G
Sbjct: 246 VTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYG 305

Query: 282 LGDQRYTAPWRAAAQRCLQGLWGRASRDSPGP 313
                +   ++     CL+   G    D+  P
Sbjct: 306 FLSDNFRQSFQKVL--CLRKGSGAKDADATEP 335


>gi|9789897 leukotriene B4 receptor 2 [Homo sapiens]
          Length = 389

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 80/273 (29%), Positives = 102/273 (37%), Gaps = 49/273 (17%)

Query: 22  LALASLI-ITANLLLALGIAWDRRLRSPP-AGCFFLSLLLAG----LLTGLALPTLPG-L 74
           L LA+L+ +  N  +   +A  R  R  P A    L L LA     LLT L +  L    
Sbjct: 58  LLLAALLGLPGNGFVVWSLAGWRPARGRPLAATLVLHLALADGAVLLLTPLFVAFLTRQA 117

Query: 75  WNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRP-----LQPPGSIRLALL 129
           W   + G   C  VY     S  + +    L+  +R +AV RP     L+ P   R  LL
Sbjct: 118 WPLGQAG---CKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFLAPRLRSPALARRLLL 174

Query: 130 LTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGAAAFLSVRVL 189
             W   LL A +PA  + H      C  Q   P+P             V AAA LS+  L
Sbjct: 175 AVWLAALLLA-VPAAVYRHLWRDRVC--QLCHPSP-------------VHAAAHLSLETL 218

Query: 190 ATAHRQLQDICRLERAVCRDEPSALARALTW-------RQARAQAGAMLLFGLCWGPYVA 242
                    +       C     A  R   W       R  R  +  +L FGL W PY A
Sbjct: 219 TAFVLPFGLMLG-----CYSVTLARLRGARWGSGRHGARVGRLVSAIVLAFGLLWAPYHA 273

Query: 243 TLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAA 275
             LL  +A    PP G     +L  LG A  AA
Sbjct: 274 VNLLQAVA-ALAPPEG-----ALAKLGGAGQAA 300


>gi|223633986 trace amine associated receptor 5 [Homo sapiens]
          Length = 337

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 58/247 (23%), Positives = 104/247 (42%), Gaps = 24/247 (9%)

Query: 27  LIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLLTGLA---LPTLPGLWNQSRRGYW 83
           +I+  N+ +A  +++ + L +P      LSL LA +  GL    L T+  + +    G +
Sbjct: 47  IIVLGNVFVAFAVSYFKALHTP-TNFLLLSLALADMFLGLLVLPLSTIRSVESCWFFGDF 105

Query: 84  SCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQPPG--SIRLAL---LLTWAGPLLF 138
            C L         L+ + +L  +  +R+ A+  PL  P   ++R+AL   L  W  P  +
Sbjct: 106 LCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAGWGVPAAY 165

Query: 139 ASL------PALGWNHWTPGANC--SSQAIFPAPYLYLEVYGLLLPAVGAAAFLSVRVLA 190
            SL           + W     C  S Q +    + +L      +P +   + L V++  
Sbjct: 166 TSLFLYTDVVETRLSQWLEEMPCVGSCQLLLNKFWGWLNFPLFFVPCLIMIS-LYVKIFV 224

Query: 191 TAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPYVATLLLSVLA 250
            A RQ Q I  L +++      A A     + A+    A+ ++ LCW P+    ++  L 
Sbjct: 225 VATRQAQQITTLSKSL------AGAAKHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLL 278

Query: 251 YEQRPPL 257
           +   PPL
Sbjct: 279 HFITPPL 285


>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
          Length = 520

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 46/152 (30%), Positives = 67/152 (44%), Gaps = 24/152 (15%)

Query: 17  ALGLSLALASLIITA---NLLLALGIAWDRRLRSPPAGCFFLSLLLAGLLTGLALPTLPG 73
           A+ + L L + I+ A   N+L+ L +A +R LR+ P   F ++L +A LL  L+   LP 
Sbjct: 45  AISVGLVLGAFILFAIVGNILVILSVACNRHLRT-PTNYFIVNLAMADLL--LSFTVLPF 101

Query: 74  LWNQSRRGYWSCLLVY---------LAPNFSFLSLLANLLLVHGERYMAVLRPLQPPGSI 124
                  GYW    ++         L    S LSL A    +  +RY+ V   LQ P  +
Sbjct: 102 SAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCA----ISIDRYIGVRYSLQYPTLV 157

Query: 125 R-----LALLLTWAGPLLFASLPALGWNHWTP 151
                 LALL  W    + +  P LGW    P
Sbjct: 158 TRRKAILALLSVWVLSTVISIGPLLGWKEPAP 189


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,775,097
Number of Sequences: 37866
Number of extensions: 622454
Number of successful extensions: 1933
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 140
Number of HSP's that attempted gapping in prelim test: 1848
Number of HSP's gapped (non-prelim): 181
length of query: 330
length of database: 18,247,518
effective HSP length: 103
effective length of query: 227
effective length of database: 14,347,320
effective search space: 3256841640
effective search space used: 3256841640
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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