Guide to the Human Genome
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Search of human proteins with 116284368

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116284368 peroxisome proliferative activated receptor gamma
isoform 1 [Homo sapiens]
         (477 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116284373 peroxisome proliferative activated receptor gamma i...   959   0.0  
gi|20336229 peroxisome proliferative activated receptor gamma is...   959   0.0  
gi|116284368 peroxisome proliferative activated receptor gamma i...   959   0.0  
gi|116284370 peroxisome proliferative activated receptor gamma i...   959   0.0  
gi|5453940 peroxisome proliferative activated receptor, delta is...   516   e-146
gi|50348666 peroxisome proliferative activated receptor, alpha [...   510   e-144
gi|7549811 peroxisome proliferative activated receptor, alpha [H...   510   e-144
gi|29171750 peroxisome proliferative activated receptor, delta i...   401   e-112
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]   175   7e-44
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]    175   7e-44
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]     175   7e-44
gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]     174   1e-43
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]   173   3e-43
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]     173   3e-43
gi|194294519 nuclear receptor subfamily 1, group H, member 3 iso...   160   2e-39
gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso...   160   2e-39
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]        155   6e-38
gi|4506755 retinoid X receptor, alpha [Homo sapiens]                  150   3e-36
gi|85362735 nuclear receptor subfamily 1, group H, member 2 [Hom...   146   4e-35
gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo...   145   6e-35
gi|14702164 nuclear receptor subfamily 1, group I, member 2 isof...   139   6e-33
gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Hom...   135   8e-32
gi|7657395 photoreceptor-specific nuclear receptor isoform b [Ho...   134   1e-31
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof...   133   4e-31
gi|224177493 nuclear receptor subfamily 1, group D, member 2 iso...   132   7e-31
gi|224177491 nuclear receptor subfamily 1, group D, member 2 iso...   132   7e-31
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo...   131   2e-30
gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Hom...   125   6e-29
gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Hom...   125   6e-29
gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo...   124   2e-28

>gi|116284373 peroxisome proliferative activated receptor gamma
           isoform 1 [Homo sapiens]
          Length = 477

 Score =  959 bits (2480), Expect = 0.0
 Identities = 477/477 (100%), Positives = 477/477 (100%)

Query: 1   MTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDP 60
           MTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDP
Sbjct: 1   MTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDP 60

Query: 61  VVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASG 120
           VVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASG
Sbjct: 61  VVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASG 120

Query: 121 FHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAI 180
           FHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAI
Sbjct: 121 FHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAI 180

Query: 181 RFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGK 240
           RFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGK
Sbjct: 181 RFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGK 240

Query: 241 TTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYA 300
           TTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYA
Sbjct: 241 TTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYA 300

Query: 301 KSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF 360
           KSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF
Sbjct: 301 KSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF 360

Query: 361 GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQ 420
           GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQ
Sbjct: 361 GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQ 420

Query: 421 LKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 477
           LKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
Sbjct: 421 LKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 477


>gi|20336229 peroxisome proliferative activated receptor gamma
           isoform 2 [Homo sapiens]
          Length = 505

 Score =  959 bits (2480), Expect = 0.0
 Identities = 477/477 (100%), Positives = 477/477 (100%)

Query: 1   MTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDP 60
           MTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDP
Sbjct: 29  MTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDP 88

Query: 61  VVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASG 120
           VVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASG
Sbjct: 89  VVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASG 148

Query: 121 FHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAI 180
           FHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAI
Sbjct: 149 FHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAI 208

Query: 181 RFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGK 240
           RFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGK
Sbjct: 209 RFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGK 268

Query: 241 TTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYA 300
           TTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYA
Sbjct: 269 TTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYA 328

Query: 301 KSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF 360
           KSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF
Sbjct: 329 KSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF 388

Query: 361 GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQ 420
           GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQ
Sbjct: 389 GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQ 448

Query: 421 LKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 477
           LKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
Sbjct: 449 LKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 505


>gi|116284368 peroxisome proliferative activated receptor gamma
           isoform 1 [Homo sapiens]
          Length = 477

 Score =  959 bits (2480), Expect = 0.0
 Identities = 477/477 (100%), Positives = 477/477 (100%)

Query: 1   MTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDP 60
           MTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDP
Sbjct: 1   MTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDP 60

Query: 61  VVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASG 120
           VVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASG
Sbjct: 61  VVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASG 120

Query: 121 FHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAI 180
           FHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAI
Sbjct: 121 FHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAI 180

Query: 181 RFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGK 240
           RFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGK
Sbjct: 181 RFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGK 240

Query: 241 TTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYA 300
           TTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYA
Sbjct: 241 TTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYA 300

Query: 301 KSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF 360
           KSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF
Sbjct: 301 KSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF 360

Query: 361 GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQ 420
           GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQ
Sbjct: 361 GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQ 420

Query: 421 LKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 477
           LKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
Sbjct: 421 LKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 477


>gi|116284370 peroxisome proliferative activated receptor gamma
           isoform 1 [Homo sapiens]
          Length = 477

 Score =  959 bits (2480), Expect = 0.0
 Identities = 477/477 (100%), Positives = 477/477 (100%)

Query: 1   MTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDP 60
           MTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDP
Sbjct: 1   MTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDP 60

Query: 61  VVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASG 120
           VVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASG
Sbjct: 61  VVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASG 120

Query: 121 FHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAI 180
           FHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAI
Sbjct: 121 FHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAI 180

Query: 181 RFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGK 240
           RFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGK
Sbjct: 181 RFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGK 240

Query: 241 TTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYA 300
           TTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYA
Sbjct: 241 TTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYA 300

Query: 301 KSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF 360
           KSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF
Sbjct: 301 KSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF 360

Query: 361 GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQ 420
           GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQ
Sbjct: 361 GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQ 420

Query: 421 LKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 477
           LKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
Sbjct: 421 LKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 477


>gi|5453940 peroxisome proliferative activated receptor, delta
           isoform 1 [Homo sapiens]
          Length = 441

 Score =  516 bits (1329), Expect = e-146
 Identities = 249/396 (62%), Positives = 319/396 (80%), Gaps = 4/396 (1%)

Query: 83  ASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLK 142
           +SPP   ++ Q+     +  S   + +ECRVCGDKASGFHYGVHACEGCKGFFRRTIR+K
Sbjct: 49  SSPPSLLDQLQM---GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMK 105

Query: 143 LIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDI- 201
           L Y++C+ +C+I KK+RNKCQYCRFQKCLA+GMSHNAIRFGRMP+AEK KL+A ++++  
Sbjct: 106 LEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEG 165

Query: 202 DQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDK 261
            Q NP+ ADL+A +KH+Y++Y+K+F +TK KAR+ILTGK +  +PFVI+D+ +L   E  
Sbjct: 166 SQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKG 225

Query: 262 IKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYG 321
           + +K +       KE+++ +F  CQ  +VE V+E+TE+AKSIP F +L LNDQVTLLKYG
Sbjct: 226 LVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYG 285

Query: 322 VHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDD 381
           VHE I+ MLAS++NKDG+L++ G GF+TREFL+SLRKPF D +EPKFEFAVKFNALELDD
Sbjct: 286 VHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDD 345

Query: 382 SDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTD 441
           SDLA+FIA IIL GDRPGL+NV  +E IQD +L+ALE  L+ NHP++  LF KLLQKM D
Sbjct: 346 SDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMAD 405

Query: 442 LRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 477
           LRQ+VTEH Q++Q IKKTET+ SLHPLLQEIYKD+Y
Sbjct: 406 LRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY 441


>gi|50348666 peroxisome proliferative activated receptor, alpha
           [Homo sapiens]
          Length = 468

 Score =  510 bits (1313), Expect = e-144
 Identities = 251/399 (62%), Positives = 315/399 (78%), Gaps = 3/399 (0%)

Query: 80  VEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTI 139
           + PAS P       +     E PS +L  IECR+CGDKASG+HYGVHACEGCKGFFRRTI
Sbjct: 72  LSPASSPSSVTYPVVPGSVDESPSGALN-IECRICGDKASGYHYGVHACEGCKGFFRRTI 130

Query: 140 RLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEI-S 198
           RLKL+YD+CD +C+I KK+RNKCQYCRF KCL+VGMSHNAIRFGRMP++EK KL AEI +
Sbjct: 131 RLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILT 190

Query: 199 SDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMG 258
            + D  + E+ADL++LAK +Y++Y+K+F + K KAR IL+GK ++  PFVI+DM +L M 
Sbjct: 191 CEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMA 250

Query: 259 EDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLL 318
           E  +  K +     Q+KE  +RIF  CQ  SVE V E+TE+AK+IPGF NLDLNDQVTLL
Sbjct: 251 EKTLVAKLVAN-GIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLL 309

Query: 319 KYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALE 378
           KYGV+E I+ ML+S+MNKDG+L++ G GF+TREFLKSLRKPF D MEPKF+FA+KFNALE
Sbjct: 310 KYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALE 369

Query: 379 LDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQK 438
           LDDSD+++F+A II  GDRPGLLNV  IE +Q+ ++  L L L+ NHP+   LF KLLQK
Sbjct: 370 LDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQK 429

Query: 439 MTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 477
           M DLRQ+VTEH QL+Q+IKKTE+D +LHPLLQEIY+D+Y
Sbjct: 430 MADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY 468


>gi|7549811 peroxisome proliferative activated receptor, alpha [Homo
           sapiens]
          Length = 468

 Score =  510 bits (1313), Expect = e-144
 Identities = 251/399 (62%), Positives = 315/399 (78%), Gaps = 3/399 (0%)

Query: 80  VEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTI 139
           + PAS P       +     E PS +L  IECR+CGDKASG+HYGVHACEGCKGFFRRTI
Sbjct: 72  LSPASSPSSVTYPVVPGSVDESPSGALN-IECRICGDKASGYHYGVHACEGCKGFFRRTI 130

Query: 140 RLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEI-S 198
           RLKL+YD+CD +C+I KK+RNKCQYCRF KCL+VGMSHNAIRFGRMP++EK KL AEI +
Sbjct: 131 RLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILT 190

Query: 199 SDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMG 258
            + D  + E+ADL++LAK +Y++Y+K+F + K KAR IL+GK ++  PFVI+DM +L M 
Sbjct: 191 CEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMA 250

Query: 259 EDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLL 318
           E  +  K +     Q+KE  +RIF  CQ  SVE V E+TE+AK+IPGF NLDLNDQVTLL
Sbjct: 251 EKTLVAKLVAN-GIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLL 309

Query: 319 KYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALE 378
           KYGV+E I+ ML+S+MNKDG+L++ G GF+TREFLKSLRKPF D MEPKF+FA+KFNALE
Sbjct: 310 KYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALE 369

Query: 379 LDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQK 438
           LDDSD+++F+A II  GDRPGLLNV  IE +Q+ ++  L L L+ NHP+   LF KLLQK
Sbjct: 370 LDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQK 429

Query: 439 MTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 477
           M DLRQ+VTEH QL+Q+IKKTE+D +LHPLLQEIY+D+Y
Sbjct: 430 MADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY 468


>gi|29171750 peroxisome proliferative activated receptor, delta
           isoform 2 [Homo sapiens]
          Length = 361

 Score =  401 bits (1030), Expect = e-112
 Identities = 193/314 (61%), Positives = 251/314 (79%), Gaps = 4/314 (1%)

Query: 83  ASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLK 142
           +SPP   ++ Q+     +  S   + +ECRVCGDKASGFHYGVHACEGCKGFFRRTIR+K
Sbjct: 49  SSPPSLLDQLQM---GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMK 105

Query: 143 LIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDI- 201
           L Y++C+ +C+I KK+RNKCQYCRFQKCLA+GMSHNAIRFGRMP+AEK KL+A ++++  
Sbjct: 106 LEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEG 165

Query: 202 DQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDK 261
            Q NP+ ADL+A +KH+Y++Y+K+F +TK KAR+ILTGK +  +PFVI+D+ +L   E  
Sbjct: 166 SQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKG 225

Query: 262 IKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYG 321
           + +K +       KE+++ +F  CQ  +VE V+E+TE+AKSIP F +L LNDQVTLLKYG
Sbjct: 226 LVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYG 285

Query: 322 VHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDD 381
           VHE I+ MLAS++NKDG+L++ G GF+TREFL+SLRKPF D +EPKFEFAVKFNALELDD
Sbjct: 286 VHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDD 345

Query: 382 SDLAIFIAVIILSG 395
           SDLA+FIA IIL G
Sbjct: 346 SDLALFIAAIILCG 359


>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score =  175 bits (444), Expect = 7e-44
 Identities = 119/390 (30%), Positives = 195/390 (50%), Gaps = 42/390 (10%)

Query: 89  SEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYD-R 147
           S   ++   P   P    +   C VC DK+SG+HYGV ACEGCKGFFRR+I+  ++Y   
Sbjct: 66  SSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCH 125

Query: 148 CDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPE 207
            D NC I+K +RN+CQYCR QKC  VGMS  ++R  R    +K+++     S+   L PE
Sbjct: 126 RDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDR--NKKKKEVPKPECSESYTLTPE 183

Query: 208 SADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHI 267
             +   L + +  ++ ++FP     A   L   TT+ S                      
Sbjct: 184 VGE---LIEKVRKAHQETFP-----ALCQLGKYTTNNS---------------------- 213

Query: 268 TPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIY 327
               EQ   + I ++      S + + +  E+AK +PGF  L + DQ+TLLK    +I+ 
Sbjct: 214 ---SEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILI 270

Query: 328 TMLAS--LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLA 385
             + +     +D +  S+G   +T    +     FG   +  F FA +   LE+DD++  
Sbjct: 271 LRICTRYTPEQDTMTFSDG---LTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETG 327

Query: 386 IFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQI 445
           +  A+ ++ GDR  L     ++ +Q+ LL+AL++ ++   P    +F K+L K+TDLR I
Sbjct: 328 LLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSI 387

Query: 446 VTEHVQLLQVIKKTETDMSLHPLLQEIYKD 475
             +  + + +  K E   S+ PL+QE+ ++
Sbjct: 388 SAKGAERV-ITLKMEIPGSMPPLIQEMLEN 416


>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
          Length = 457

 Score =  175 bits (444), Expect = 7e-44
 Identities = 119/390 (30%), Positives = 195/390 (50%), Gaps = 42/390 (10%)

Query: 89  SEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYD-R 147
           S   ++   P   P    +   C VC DK+SG+HYGV ACEGCKGFFRR+I+  ++Y   
Sbjct: 61  SSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCH 120

Query: 148 CDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPE 207
            D NC I+K +RN+CQYCR QKC  VGMS  ++R  R    +K+++     S+   L PE
Sbjct: 121 RDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDR--NKKKKEVPKPECSESYTLTPE 178

Query: 208 SADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHI 267
             +   L + +  ++ ++FP     A   L   TT+ S                      
Sbjct: 179 VGE---LIEKVRKAHQETFP-----ALCQLGKYTTNNS---------------------- 208

Query: 268 TPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIY 327
               EQ   + I ++      S + + +  E+AK +PGF  L + DQ+TLLK    +I+ 
Sbjct: 209 ---SEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILI 265

Query: 328 TMLAS--LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLA 385
             + +     +D +  S+G   +T    +     FG   +  F FA +   LE+DD++  
Sbjct: 266 LRICTRYTPEQDTMTFSDG---LTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETG 322

Query: 386 IFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQI 445
           +  A+ ++ GDR  L     ++ +Q+ LL+AL++ ++   P    +F K+L K+TDLR I
Sbjct: 323 LLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSI 382

Query: 446 VTEHVQLLQVIKKTETDMSLHPLLQEIYKD 475
             +  + + +  K E   S+ PL+QE+ ++
Sbjct: 383 SAKGAERV-ITLKMEIPGSMPPLIQEMLEN 411


>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score =  175 bits (444), Expect = 7e-44
 Identities = 119/390 (30%), Positives = 195/390 (50%), Gaps = 42/390 (10%)

Query: 89  SEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYD-R 147
           S   ++   P   P    +   C VC DK+SG+HYGV ACEGCKGFFRR+I+  ++Y   
Sbjct: 66  SSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCH 125

Query: 148 CDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPE 207
            D NC I+K +RN+CQYCR QKC  VGMS  ++R  R    +K+++     S+   L PE
Sbjct: 126 RDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDR--NKKKKEVPKPECSESYTLTPE 183

Query: 208 SADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHI 267
             +   L + +  ++ ++FP     A   L   TT+ S                      
Sbjct: 184 VGE---LIEKVRKAHQETFP-----ALCQLGKYTTNNS---------------------- 213

Query: 268 TPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIY 327
               EQ   + I ++      S + + +  E+AK +PGF  L + DQ+TLLK    +I+ 
Sbjct: 214 ---SEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILI 270

Query: 328 TMLAS--LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLA 385
             + +     +D +  S+G   +T    +     FG   +  F FA +   LE+DD++  
Sbjct: 271 LRICTRYTPEQDTMTFSDG---LTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETG 327

Query: 386 IFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQI 445
           +  A+ ++ GDR  L     ++ +Q+ LL+AL++ ++   P    +F K+L K+TDLR I
Sbjct: 328 LLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSI 387

Query: 446 VTEHVQLLQVIKKTETDMSLHPLLQEIYKD 475
             +  + + +  K E   S+ PL+QE+ ++
Sbjct: 388 SAKGAERV-ITLKMEIPGSMPPLIQEMLEN 416


>gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]
          Length = 448

 Score =  174 bits (442), Expect = 1e-43
 Identities = 116/368 (31%), Positives = 191/368 (51%), Gaps = 42/368 (11%)

Query: 111 CRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYD-RCDLNCRIHKKSRNKCQYCRFQK 169
           C VC DK+SG+HYGV ACEGCKGFFRR+I+  +IY    D NC I+K +RN+CQYCR QK
Sbjct: 81  CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQK 140

Query: 170 CLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLT 229
           C  VGMS  ++R  R  + +KE    E +   +     +A+L  L + +  ++ ++FP  
Sbjct: 141 CFEVGMSKESVRNDR-NKKKKETSKQECTESYEM----TAELDDLTEKIRKAHQETFP-- 193

Query: 230 KAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRS 289
                    GK T  S             + +++      L ++  E+A           
Sbjct: 194 ----SLCQLGKYTTNS-----------SADHRVRLD--LGLWDKFSELA----------- 225

Query: 290 VEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLAS--LMNKDGVLISEGQGF 347
            + + +I E+AK +PGF  L + DQ+TLLK    +I+   + +     +D +  S+G   
Sbjct: 226 TKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDG--- 282

Query: 348 MTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIE 407
           +T    +     FG   +  F FA +   LE+DD++  +  A+ ++ GDR  L     ++
Sbjct: 283 LTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVD 342

Query: 408 DIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHP 467
            +Q+ LL+AL++ ++   P    +F K+L K+TDLR I  +  + + +  K E   S+ P
Sbjct: 343 KLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERV-ITLKMEIPGSMPP 401

Query: 468 LLQEIYKD 475
           L+QE+ ++
Sbjct: 402 LIQEMLEN 409


>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
          Length = 443

 Score =  173 bits (439), Expect = 3e-43
 Identities = 113/368 (30%), Positives = 188/368 (51%), Gaps = 42/368 (11%)

Query: 111 CRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYD-RCDLNCRIHKKSRNKCQYCRFQK 169
           C VC DK+SG+HYGV +CEGCKGFFRR+I+  ++Y    D NC I+K +RN+CQYCR QK
Sbjct: 79  CFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 138

Query: 170 CLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLT 229
           C  VGMS  A+R  R    +K+++  E S D  +L+P+   L  L   +  ++ ++FP  
Sbjct: 139 CFEVGMSKEAVRNDR--NKKKKEVKEEGSPDSYELSPQ---LEELITKVSKAHQETFP-- 191

Query: 230 KAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRS 289
                    GK T  S                          +   ++ + ++      +
Sbjct: 192 ----SLCQLGKYTTNSS------------------------ADHRVQLDLGLWDKFSELA 223

Query: 290 VEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLAS--LMNKDGVLISEGQGF 347
            + + +I E+AK +PGF  L + DQ+TLLK    +I+   + +     +D +  S+G   
Sbjct: 224 TKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDG--- 280

Query: 348 MTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIE 407
           +T    +     FG   +  F FA +   LE+DD++  +  A+ ++ GDR  L   + ++
Sbjct: 281 LTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVD 340

Query: 408 DIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHP 467
            +Q+ LL+AL L  +   P    +F ++L K+TDLR I T+  +   +  K E    + P
Sbjct: 341 KLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAE-RAITLKMEIPGPMPP 399

Query: 468 LLQEIYKD 475
           L++E+ ++
Sbjct: 400 LIREMLEN 407


>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
          Length = 454

 Score =  173 bits (439), Expect = 3e-43
 Identities = 113/368 (30%), Positives = 188/368 (51%), Gaps = 42/368 (11%)

Query: 111 CRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYD-RCDLNCRIHKKSRNKCQYCRFQK 169
           C VC DK+SG+HYGV +CEGCKGFFRR+I+  ++Y    D NC I+K +RN+CQYCR QK
Sbjct: 90  CFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 149

Query: 170 CLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLT 229
           C  VGMS  A+R  R    +K+++  E S D  +L+P+   L  L   +  ++ ++FP  
Sbjct: 150 CFEVGMSKEAVRNDR--NKKKKEVKEEGSPDSYELSPQ---LEELITKVSKAHQETFP-- 202

Query: 230 KAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRS 289
                    GK T  S                          +   ++ + ++      +
Sbjct: 203 ----SLCQLGKYTTNSS------------------------ADHRVQLDLGLWDKFSELA 234

Query: 290 VEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLAS--LMNKDGVLISEGQGF 347
            + + +I E+AK +PGF  L + DQ+TLLK    +I+   + +     +D +  S+G   
Sbjct: 235 TKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDG--- 291

Query: 348 MTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIE 407
           +T    +     FG   +  F FA +   LE+DD++  +  A+ ++ GDR  L   + ++
Sbjct: 292 LTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVD 351

Query: 408 DIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHP 467
            +Q+ LL+AL L  +   P    +F ++L K+TDLR I T+  +   +  K E    + P
Sbjct: 352 KLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAE-RAITLKMEIPGPMPP 410

Query: 468 LLQEIYKD 475
           L++E+ ++
Sbjct: 411 LIREMLEN 418


>gi|194294519 nuclear receptor subfamily 1, group H, member 3
           isoform c [Homo sapiens]
          Length = 402

 Score =  160 bits (405), Expect = 2e-39
 Identities = 115/399 (28%), Positives = 188/399 (47%), Gaps = 33/399 (8%)

Query: 83  ASPPYYSEKTQLY-NKPHEEPSNSLMAIE-CRVCGDKASGFHYGVHACEGCKGFFRRTIR 140
           A PP  SE T++   K  + P+  ++  E C VCGDKASGFHY V +CEGCKGFFRR++ 
Sbjct: 25  AEPP--SEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSV- 81

Query: 141 LKLIYDRCDL--NCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEIS 198
           +K  +  C    +C +    R KCQ CR +KC   GM    +      + +K K   E  
Sbjct: 82  IKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQ 141

Query: 199 SDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMG 258
           +    L P ++    +   L    +       A  +       +D+     + M      
Sbjct: 142 AHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHS 201

Query: 259 ED--KIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVT 316
            +  + +F H T L                  ++ +VQEI ++AK +PGF+ L   DQ+ 
Sbjct: 202 REARQQRFAHFTEL------------------AIVSVQEIVDFAKQLPGFLQLSREDQIA 243

Query: 317 LLKYGVHEIIYTMLASLMN--KDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKF 374
           LLK    E++    +   N   + +   +   +   +F K+  +   +F+ P FEF+   
Sbjct: 244 LLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQV--EFINPIFEFSRAM 301

Query: 375 NALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAK 434
           N L+L+D++ A+ IA+ I S DRP + +   +E +Q   ++AL   + ++HP    +F +
Sbjct: 302 NELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPR 361

Query: 435 LLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIY 473
           +L K+  LR + + H +  QV      D  L PLL EI+
Sbjct: 362 MLMKLVSLRTLSSVHSE--QVFALRLQDKKLPPLLSEIW 398


>gi|194294517 nuclear receptor subfamily 1, group H, member 3
           isoform a [Homo sapiens]
          Length = 447

 Score =  160 bits (405), Expect = 2e-39
 Identities = 115/399 (28%), Positives = 188/399 (47%), Gaps = 33/399 (8%)

Query: 83  ASPPYYSEKTQLY-NKPHEEPSNSLMAIE-CRVCGDKASGFHYGVHACEGCKGFFRRTIR 140
           A PP  SE T++   K  + P+  ++  E C VCGDKASGFHY V +CEGCKGFFRR++ 
Sbjct: 70  AEPP--SEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSV- 126

Query: 141 LKLIYDRCDL--NCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEIS 198
           +K  +  C    +C +    R KCQ CR +KC   GM    +      + +K K   E  
Sbjct: 127 IKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQ 186

Query: 199 SDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMG 258
           +    L P ++    +   L    +       A  +       +D+     + M      
Sbjct: 187 AHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHS 246

Query: 259 ED--KIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVT 316
            +  + +F H T L                  ++ +VQEI ++AK +PGF+ L   DQ+ 
Sbjct: 247 REARQQRFAHFTEL------------------AIVSVQEIVDFAKQLPGFLQLSREDQIA 288

Query: 317 LLKYGVHEIIYTMLASLMN--KDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKF 374
           LLK    E++    +   N   + +   +   +   +F K+  +   +F+ P FEF+   
Sbjct: 289 LLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQV--EFINPIFEFSRAM 346

Query: 375 NALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAK 434
           N L+L+D++ A+ IA+ I S DRP + +   +E +Q   ++AL   + ++HP    +F +
Sbjct: 347 NELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPR 406

Query: 435 LLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIY 473
           +L K+  LR + + H +  QV      D  L PLL EI+
Sbjct: 407 MLMKLVSLRTLSSVHSE--QVFALRLQDKKLPPLLSEIW 443


>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
          Length = 463

 Score =  155 bits (393), Expect = 6e-38
 Identities = 114/381 (29%), Positives = 180/381 (47%), Gaps = 54/381 (14%)

Query: 96  NKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYD-RCDLNCRI 154
           N P   P  SL+   C +CGD++SG HYGV++CEGCKGFF+RTIR  LIY  R + +C I
Sbjct: 125 NYPSTSPG-SLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLI 183

Query: 155 HKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRAL 214
            K+ RN+CQYCR+QKCL +GM   A++  R    E+ +  AE ++   +  P        
Sbjct: 184 DKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMP-------- 235

Query: 215 AKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQS 274
            + + ++ +   P T++     +   T D        + ++    DK  F          
Sbjct: 236 VERILEAELAVEPKTESYGDMNMENSTND-------PVTNICHAADKQLF---------- 278

Query: 275 KEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLA--S 332
                                + E+AK IP F +L L DQV LL+ G +E++    +  S
Sbjct: 279 --------------------TLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRS 318

Query: 333 LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVII 392
           +  +DG+L++ G   + R    S       F     E   K   +++D S+L    A+++
Sbjct: 319 VSVQDGILLATGL-HVHRSSAHSAGVG-SIFDRVLTELVSKMKDMQMDKSELGCLRAIVL 376

Query: 393 LSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQI---VTEH 449
            + D  GL N   +E +++ +   LE   K  +PE    FAKLL ++  LR I     EH
Sbjct: 377 FNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEH 436

Query: 450 VQLLQVIKKTETDMSLHPLLQ 470
           +   ++I  T  D  L  +L+
Sbjct: 437 LFFFKLIGDTPIDTFLMEMLE 457


>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
          Length = 462

 Score =  150 bits (378), Expect = 3e-36
 Identities = 107/367 (29%), Positives = 176/367 (47%), Gaps = 52/367 (14%)

Query: 111 CRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYD-RCDLNCRIHKKSRNKCQYCRFQK 169
           C +CGD++SG HYGV++CEGCKGFF+RT+R  L Y  R + +C I K+ RN+CQYCR+QK
Sbjct: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194

Query: 170 CLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLT 229
           CLA+GM   A++  R    ++ +   E +S  ++  P         + + ++ +   P T
Sbjct: 195 CLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMP--------VERILEAELAVEPKT 246

Query: 230 KAKARAIL-TGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFR 288
           +    A +    ++   P     + ++    DK  F                        
Sbjct: 247 ETYVEANMGLNPSSPNDP-----VTNICQAADKQLF------------------------ 277

Query: 289 SVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLA--SLMNKDGVLISEGQG 346
                  + E+AK IP F  L L+DQV LL+ G +E++    +  S+  KDG+L++ G  
Sbjct: 278 ------TLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGL- 330

Query: 347 FMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPI 406
            + R    S       F     E   K   +++D ++L    A+++ + D  GL N   +
Sbjct: 331 HVHRNSAHSAGVG-AIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEV 389

Query: 407 EDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQI---VTEHVQLLQVIKKTETDM 463
           E +++ +  +LE   K  +PE    FAKLL ++  LR I     EH+   ++I  T  D 
Sbjct: 390 EALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT 449

Query: 464 SLHPLLQ 470
            L  +L+
Sbjct: 450 FLMEMLE 456


>gi|85362735 nuclear receptor subfamily 1, group H, member 2 [Homo
           sapiens]
          Length = 461

 Score =  146 bits (369), Expect = 4e-35
 Identities = 111/391 (28%), Positives = 178/391 (45%), Gaps = 19/391 (4%)

Query: 97  KPHEEPSNSLMAIE-CRVCGDKASGFHYGVHACEGCKGFFRRTI---RLKLIYDRCDLNC 152
           K  + P+  ++  E CRVCGDKASGFHY V +CEGCKGFFRR++     +    R    C
Sbjct: 72  KRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTC 131

Query: 153 RIHKKSRNKCQYCRFQKCLAVGMSHNAIRFG---RMPQAEKEKLLAEISSDIDQLNPESA 209
           ++    R KCQ CR +KC   GM    +      R  +  K++     S     + P+ +
Sbjct: 132 QMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQSPVGPQGS 191

Query: 210 DLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKH--- 266
              A          ++      +   +   + T     +I  + +  +  +K  F     
Sbjct: 192 SSSASGPGASPGGSEAGSQGSGEGEGV---QLTAAQELMIQQLVAAQLQCNKRSFSDQPK 248

Query: 267 ITP----LQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGV 322
           +TP       QS++   + F      ++ +VQEI ++AK +PGF+ L   DQ+ LLK   
Sbjct: 249 VTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKAST 308

Query: 323 HEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDS 382
            EI+    A   N +   I+  + F   +          +F+ P FEF+     L LDD+
Sbjct: 309 IEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDA 368

Query: 383 DLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDL 442
           + A+ IA+ I S DRP +     +E +Q   ++AL    ++  P+    F ++L K+  L
Sbjct: 369 EYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSL 428

Query: 443 RQIVTEHVQLLQVIKKTETDMSLHPLLQEIY 473
           R + + H +  QV      D  L PLL EI+
Sbjct: 429 RTLSSVHSE--QVFALRLQDKKLPPLLSEIW 457


>gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo
           sapiens]
          Length = 472

 Score =  145 bits (367), Expect = 6e-35
 Identities = 107/365 (29%), Positives = 171/365 (46%), Gaps = 24/365 (6%)

Query: 111 CRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDL--NCRIHKKSRNKCQYCRFQ 168
           C VCGD+ASG+HY    CEGCKGFFRR+I    +Y +C    NC +    R KCQ CR +
Sbjct: 127 CVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVY-KCKNGGNCVMDMYMRRKCQECRLR 185

Query: 169 KCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPL 228
           KC  +GM    +      Q + ++L   +    DQ   E ++ R L +            
Sbjct: 186 KCKEMGMLAECLL--TEIQCKSKRLRKNVKQHADQTVNEDSEGRDLRQ----------VT 233

Query: 229 TKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFR 288
           +  K+    T  T D+   + + M+S        +  +    +E S E    I       
Sbjct: 234 STTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEM--- 290

Query: 289 SVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFM 348
           +   VQ + E+ K +PGF  LD  DQ+ LLK    E ++   A + NK    +  G   +
Sbjct: 291 ATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKK---LPSGHSDL 347

Query: 349 TREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIED 408
             E +++      +++ P F F      L++   + A+  A++ILS DR  + + + +E 
Sbjct: 348 LEERIRNSGIS-DEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEK 406

Query: 409 IQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPL 468
           +Q+ LL  L+   K++ PE+ Q FA LL ++T+LR     H ++L  +     D    PL
Sbjct: 407 LQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEML--MSWRVNDHKFTPL 464

Query: 469 LQEIY 473
           L EI+
Sbjct: 465 LCEIW 469


>gi|14702164 nuclear receptor subfamily 1, group I, member 2 isoform
           3 [Homo sapiens]
          Length = 397

 Score =  139 bits (350), Expect = 6e-33
 Identities = 104/377 (27%), Positives = 172/377 (45%), Gaps = 39/377 (10%)

Query: 111 CRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLN---CRIHKKSRNKCQYCRF 167
           CRVCGDKA+G+H+ V  CEGCKGFFRR ++      RC      C I +K+R +CQ CR 
Sbjct: 41  CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARL-RCPFRKGACEITRKTRRQCQACRL 99

Query: 168 QKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNP-----ESADLRALAKHLYDSY 222
           +KCL  GM    I      + E+  L+    S+     P      + + R + + L D+ 
Sbjct: 100 RKCLESGMKKEMIMSDEAVE-ERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQ 158

Query: 223 IKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIF 282
           +K+F               T  S F  + ++  + GED   + +  P     KE+   + 
Sbjct: 159 MKTF--------------DTTFSHFKNFRVSLQLRGEDGSVWNYKPPADSGGKEI-FSLL 203

Query: 283 QGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLIS 342
                 S    + I  +AK I  F +L + DQ++LLK    E+      ++ N      +
Sbjct: 204 PHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFN------A 257

Query: 343 EGQGFMTREFLKSLRKPFGDF----MEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRP 398
           E   +        L    G F    +EP  +F      L+L + +  +  A+ + S DRP
Sbjct: 258 ETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRP 317

Query: 399 GLLNVKPIEDIQDNLLQALELQLKLNHPESSQ--LFAKLLQKMTDLRQIVTEHVQLLQVI 456
           G+L  + ++ +Q+     L+  ++ N P+ +   LF K++  +T+LR I  +H Q L  I
Sbjct: 318 GVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRI 377

Query: 457 KKTETDMSLHPLLQEIY 473
           +      +  PL+QE++
Sbjct: 378 QDIHPFAT--PLMQELF 392


>gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Homo
           sapiens]
          Length = 614

 Score =  135 bits (340), Expect = 8e-32
 Identities = 60/101 (59%), Positives = 81/101 (80%), Gaps = 2/101 (1%)

Query: 107 MAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQY 164
           M + C+VCGD ASGFHYGVHACEGCKGFFRR+I+  + Y RC  + NC I + +RN+CQ 
Sbjct: 128 MVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQ 187

Query: 165 CRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLN 205
           CRF+KCL+VGMS +A+RFGR+P+ EK+++LAE+ S ++  N
Sbjct: 188 CRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLAN 228



 Score =  108 bits (271), Expect = 8e-24
 Identities = 62/163 (38%), Positives = 96/163 (58%), Gaps = 3/163 (1%)

Query: 292 AVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMN-KDGVLISEGQGFMTR 350
           AV+E+ E+AK IPGF +L  +DQVTLLK G  E++    ASL N KD  ++   +   + 
Sbjct: 446 AVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSL 505

Query: 351 EFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQ 410
           + L ++    GD +   F+F+ K N+L L + +L +F AV+++S DR G+ N   +E +Q
Sbjct: 506 QELGAMG--MGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGMENSASVEQLQ 563

Query: 411 DNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLL 453
           + LL+AL   +  N P  +  F KLL K+ DLR +   H + L
Sbjct: 564 ETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKL 606


>gi|7657395 photoreceptor-specific nuclear receptor isoform b [Homo
           sapiens]
          Length = 410

 Score =  134 bits (338), Expect = 1e-31
 Identities = 117/394 (29%), Positives = 189/394 (47%), Gaps = 37/394 (9%)

Query: 100 EEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLN---CRIHK 156
           E+P+    +++CRVCGD +SG HYG++AC GC GFF+R++R +LIY RC +    C + K
Sbjct: 36  EDPTGVSPSLQCRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIY-RCQVGAGMCPVDK 94

Query: 157 KSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAK 216
             RN+CQ CR +KCL  GM+ +A++  R P++  +  L  + S+ +   PES  L A   
Sbjct: 95  AHRNQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTES-RPES--LVAPPA 151

Query: 217 HLYDSYIKSFPLTKAKA------RAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPL 270
               S     P++ A+A       +++T +T  K      D N  +   D  +F   +P 
Sbjct: 152 PAGRSPRGPTPMSAARALGHHFMASLITAETCAKLEPEDADENIDVTSNDP-EFPS-SPY 209

Query: 271 QEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHE--IIYT 328
              S      I +     S   +    ++AK++P F +L   DQV LL+    E  ++  
Sbjct: 210 SSSSPCGLDSIHE----TSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGA 265

Query: 329 MLASLMNKDGVLI-----SEGQGFMTREFLKSLRKPFGDFMEPKF--EFAVKFNALELDD 381
           +  SL      L+     S   G   R  L S        ME +   E   +F AL +D 
Sbjct: 266 IQWSLPLDSCPLLAPPEASAAGGAQGRLTLAS--------METRVLQETISRFRALAVDP 317

Query: 382 SDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTD 441
           ++ A   A+++   +  GL + + +E +QD     L    K +HP     F KLL  +  
Sbjct: 318 TEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPS 377

Query: 442 LRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKD 475
           LR I  E ++LL   +KT  +  +  LL +++K+
Sbjct: 378 LRFITAERIELL-FFRKTIGNTPMEKLLCDMFKN 410


>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
           a [Homo sapiens]
          Length = 414

 Score =  133 bits (334), Expect = 4e-31
 Identities = 102/377 (27%), Positives = 163/377 (43%), Gaps = 47/377 (12%)

Query: 98  PHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYD-RCDLNCRIHK 156
           P  +       IEC VCGDK+SG HYG   CEGCK FF+R++R  L Y  R + NC I +
Sbjct: 66  PGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQ 125

Query: 157 KSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAK 216
             RN+CQYCR +KCL VGM   A++ GRMP  +       +++  D LN           
Sbjct: 126 HHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNG-DPLN----------- 173

Query: 217 HLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKE 276
               SY+  +     +A    T +                 G   ++  +I  ++   + 
Sbjct: 174 --CHSYLSGYISLLLRAEPYPTSR----------------FGSQCMQPNNIMGIENICEL 215

Query: 277 VAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASL-MN 335
            A  +F               E+A++IP F +L + DQV LL+    E+     A   M 
Sbjct: 216 AARMLFSA------------VEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMP 263

Query: 336 KDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSG 395
                +    G             F D +    E   K  AL +D ++ +   A+++ + 
Sbjct: 264 LHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTS 323

Query: 396 DRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQI---VTEHVQL 452
           D  GL +V  +E +Q+    ALE  ++  +P     F KLL ++  LR +   V E +  
Sbjct: 324 DACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFF 383

Query: 453 LQVIKKTETDMSLHPLL 469
           ++++ KT  +  +  +L
Sbjct: 384 VRLVGKTPIETLIRDML 400


>gi|224177493 nuclear receptor subfamily 1, group D, member 2
           isoform 2 [Homo sapiens]
          Length = 504

 Score =  132 bits (332), Expect = 7e-31
 Identities = 57/95 (60%), Positives = 77/95 (81%), Gaps = 2/95 (2%)

Query: 107 MAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQY 164
           M + C+VCGD ASGFHYGVHACEGCKGFFRR+I+  + Y +C  + NC I + +RN+CQ 
Sbjct: 24  MVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQ 83

Query: 165 CRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISS 199
           CRF+KCL+VGMS +A+RFGR+P+ EK+++L E+ S
Sbjct: 84  CRFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQS 118



 Score =  117 bits (292), Expect = 3e-26
 Identities = 65/168 (38%), Positives = 100/168 (59%), Gaps = 5/168 (2%)

Query: 292 AVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMN--KDGVLISEGQGFMT 349
           AV+E+ E+AK IPGF +L  +DQV LLK G  E++    ASL +  +  V    G+ +  
Sbjct: 337 AVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSV 396

Query: 350 REFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDI 409
            + L S+    GD +   FEF+ K NAL+L D ++++F AV+++S DR G+ NV  +E +
Sbjct: 397 DD-LHSMGA--GDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEAL 453

Query: 410 QDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIK 457
           Q+ L++AL   +  NHP  + +F KLL K+ DLR +   H + L   K
Sbjct: 454 QETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFK 501


>gi|224177491 nuclear receptor subfamily 1, group D, member 2
           isoform 1 [Homo sapiens]
          Length = 579

 Score =  132 bits (332), Expect = 7e-31
 Identities = 57/95 (60%), Positives = 77/95 (81%), Gaps = 2/95 (2%)

Query: 107 MAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQY 164
           M + C+VCGD ASGFHYGVHACEGCKGFFRR+I+  + Y +C  + NC I + +RN+CQ 
Sbjct: 99  MVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQ 158

Query: 165 CRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISS 199
           CRF+KCL+VGMS +A+RFGR+P+ EK+++L E+ S
Sbjct: 159 CRFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQS 193



 Score =  117 bits (292), Expect = 3e-26
 Identities = 65/168 (38%), Positives = 100/168 (59%), Gaps = 5/168 (2%)

Query: 292 AVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMN--KDGVLISEGQGFMT 349
           AV+E+ E+AK IPGF +L  +DQV LLK G  E++    ASL +  +  V    G+ +  
Sbjct: 412 AVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSV 471

Query: 350 REFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDI 409
            + L S+    GD +   FEF+ K NAL+L D ++++F AV+++S DR G+ NV  +E +
Sbjct: 472 DD-LHSMGA--GDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEAL 528

Query: 410 QDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIK 457
           Q+ L++AL   +  NHP  + +F KLL K+ DLR +   H + L   K
Sbjct: 529 QETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFK 576


>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
           sapiens]
          Length = 423

 Score =  131 bits (329), Expect = 2e-30
 Identities = 111/393 (28%), Positives = 173/393 (44%), Gaps = 51/393 (12%)

Query: 82  PASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRL 141
           PA+P    +K Q    P      S   IEC VCGDK+SG HYG   CEGCK FF+R++R 
Sbjct: 61  PATPGTAGDKGQ--GPPGS--GQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRR 116

Query: 142 KLIYD-RCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSD 200
            L Y  R + NC I +  RN+CQYCR +KCL VGM   A++ GRMP  +       +++ 
Sbjct: 117 NLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNG 176

Query: 201 IDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGED 260
            D LN                Y+  +     +A    T +                 G  
Sbjct: 177 -DPLNGH-------------CYLSGYISLLLRAEPYPTSR----------------YGSQ 206

Query: 261 KIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKY 320
            ++  +I  + E   E+A R+     F +V       E+A++IP F +L + DQV+LL+ 
Sbjct: 207 CMQPNNIMGI-ENICELAARLL----FSAV-------EWARNIPFFPDLQITDQVSLLRL 254

Query: 321 GVHEIIYTMLASL-MNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALEL 379
              E+     A   M      +    G             F D +    E   K  AL +
Sbjct: 255 TWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHV 314

Query: 380 DDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKM 439
           D ++ +   A+++ + D  GL +   IE +Q+    ALE  ++  +P     F KLL ++
Sbjct: 315 DSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRL 374

Query: 440 TDLRQI---VTEHVQLLQVIKKTETDMSLHPLL 469
             LR +   V E +  ++++ KT  +  +  +L
Sbjct: 375 PSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 407


>gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Homo
           sapiens]
          Length = 598

 Score =  125 bits (315), Expect = 6e-29
 Identities = 110/378 (29%), Positives = 176/378 (46%), Gaps = 63/378 (16%)

Query: 111 CRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIY-DRCDLNCRIHKKSRNKCQYCRFQK 169
           C VCGD AS  HYGV  CEGCKGFF+RT++    Y    + +C + K+ RN+CQ+CRFQK
Sbjct: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326

Query: 170 CLAVGMSHNAIRF-------GRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSY 222
           CLAVGM    +R        GR+P   K+              P  A    L   L  ++
Sbjct: 327 CLAVGMVKEVVRTDSLKGRRGRLPSKPKQ--------------PPDASPANLLTSLVRAH 372

Query: 223 IKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIF 282
           + S P T AK                           D  KF+ +  L    KE A  + 
Sbjct: 373 LDSGPST-AKL--------------------------DYSKFQELV-LPHFGKEDAGDVQ 404

Query: 283 QGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNK-DGVLI 341
           Q     S  +++ I ++A+ IPGF  L   DQ  LL+    E+    LA      +G LI
Sbjct: 405 QFYDLLS-GSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLI 463

Query: 342 SEGQGFMTREFLKSLR--KPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPG 399
                F +   L  L+  + FGD+++    F+   ++L +D    A   A+++++ DR G
Sbjct: 464 -----FCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLIT-DRHG 517

Query: 400 LLNVKPIEDIQDNLLQALE--LQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIK 457
           L   + +E++Q+ +   L+  +      P+ +   ++LL K+ +LR + T+ +Q +  + 
Sbjct: 518 LQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYL- 576

Query: 458 KTETDMSLHPLLQEIYKD 475
           K E  +   P++ +I+ D
Sbjct: 577 KLEDLVPPPPIIDKIFMD 594


>gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Homo
           sapiens]
          Length = 598

 Score =  125 bits (315), Expect = 6e-29
 Identities = 110/378 (29%), Positives = 176/378 (46%), Gaps = 63/378 (16%)

Query: 111 CRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIY-DRCDLNCRIHKKSRNKCQYCRFQK 169
           C VCGD AS  HYGV  CEGCKGFF+RT++    Y    + +C + K+ RN+CQ+CRFQK
Sbjct: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326

Query: 170 CLAVGMSHNAIRF-------GRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSY 222
           CLAVGM    +R        GR+P   K+              P  A    L   L  ++
Sbjct: 327 CLAVGMVKEVVRTDSLKGRRGRLPSKPKQ--------------PPDASPANLLTSLVRAH 372

Query: 223 IKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIF 282
           + S P T AK                           D  KF+ +  L    KE A  + 
Sbjct: 373 LDSGPST-AKL--------------------------DYSKFQELV-LPHFGKEDAGDVQ 404

Query: 283 QGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNK-DGVLI 341
           Q     S  +++ I ++A+ IPGF  L   DQ  LL+    E+    LA      +G LI
Sbjct: 405 QFYDLLS-GSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLI 463

Query: 342 SEGQGFMTREFLKSLR--KPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPG 399
                F +   L  L+  + FGD+++    F+   ++L +D    A   A+++++ DR G
Sbjct: 464 -----FCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLIT-DRHG 517

Query: 400 LLNVKPIEDIQDNLLQALE--LQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIK 457
           L   + +E++Q+ +   L+  +      P+ +   ++LL K+ +LR + T+ +Q +  + 
Sbjct: 518 LQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYL- 576

Query: 458 KTETDMSLHPLLQEIYKD 475
           K E  +   P++ +I+ D
Sbjct: 577 KLEDLVPPPPIIDKIFMD 594


>gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo
           sapiens]
          Length = 598

 Score =  124 bits (311), Expect = 2e-28
 Identities = 109/380 (28%), Positives = 171/380 (45%), Gaps = 62/380 (16%)

Query: 92  TQLYNKPHE-EPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIY-DRCD 149
           TQ+ + P    PSN  +   C VCGD A+  HYGV  CEGCKGFF+RT++    Y    +
Sbjct: 246 TQVPSPPSRGSPSNEGL---CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLAN 302

Query: 150 LNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRF-------GRMPQAEKEKLLAEISSDID 202
            NC + K+ RN+CQYCRFQKCLAVGM    +R        GR+P   K         +  
Sbjct: 303 KNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKS------PQEPS 356

Query: 203 QLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKI 262
             +P  + + AL +   DS      L  ++ +A               + +  M G+D  
Sbjct: 357 PPSPPVSLISALVRAHVDSNPAMTSLDYSRFQA---------------NPDYQMSGDDTQ 401

Query: 263 KFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGV 322
             +    L   S E+                  I  +A+ IPGF +L   DQ  L +   
Sbjct: 402 HIQQFYDLLTGSMEI------------------IRGWAEKIPGFADLPKADQDLLFESAF 443

Query: 323 HEIIYTMLASLMNK-DGVLISEGQGFMTREFLKSLR--KPFGDFMEPKFEFAVKFNALEL 379
            E+    LA   N  +G LI     F     L  L+  + FG++++   EF+     + +
Sbjct: 444 LELFVLRLAYRSNPVEGKLI-----FCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNI 498

Query: 380 DDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHP--ESSQLFAKLLQ 437
           D S  +  IA + +  +R GL   K +E++Q+ ++  L+  +  N+         +KLL 
Sbjct: 499 DISAFSC-IAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLG 557

Query: 438 KMTDLRQIVTEHVQLLQVIK 457
           K+ +LR + T+ +Q +  +K
Sbjct: 558 KLPELRTLCTQGLQRIFYLK 577


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,681,707
Number of Sequences: 37866
Number of extensions: 705191
Number of successful extensions: 2350
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 115
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1956
Number of HSP's gapped (non-prelim): 231
length of query: 477
length of database: 18,247,518
effective HSP length: 106
effective length of query: 371
effective length of database: 14,233,722
effective search space: 5280710862
effective search space used: 5280710862
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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