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Search of human proteins with 116256481
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
(636 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens] 1267 0.0
gi|192807309 TNFAIP3 interacting protein 3 [Homo sapiens] 173 4e-43
gi|192807305 TNFAIP3 interacting protein 3 [Homo sapiens] 173 4e-43
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 78 2e-14
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 75 1e-13
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 75 2e-13
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 74 3e-13
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 73 9e-13
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 73 9e-13
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 70 5e-12
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 70 6e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 70 6e-12
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 70 8e-12
gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens] 70 8e-12
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 70 8e-12
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 70 8e-12
gi|34577114 cytomatrix protein p110 [Homo sapiens] 69 1e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 69 1e-11
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 69 2e-11
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 69 2e-11
gi|221139761 zinc finger protein 853 [Homo sapiens] 68 2e-11
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 68 3e-11
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 68 3e-11
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 68 3e-11
gi|38044112 restin isoform b [Homo sapiens] 67 4e-11
gi|4506751 restin isoform a [Homo sapiens] 67 4e-11
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 67 5e-11
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 67 5e-11
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 67 5e-11
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho... 67 5e-11
>gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
Length = 636
Score = 1267 bits (3279), Expect = 0.0
Identities = 636/636 (100%), Positives = 636/636 (100%)
Query: 1 MEGRGPYRIYDPGGSVPSGEASAAFERLVKENSRLKEKMQGIKMLGELLEESQMEATRLR 60
MEGRGPYRIYDPGGSVPSGEASAAFERLVKENSRLKEKMQGIKMLGELLEESQMEATRLR
Sbjct: 1 MEGRGPYRIYDPGGSVPSGEASAAFERLVKENSRLKEKMQGIKMLGELLEESQMEATRLR 60
Query: 61 QKAEELVKDNELLPPPSPSLGSFDPLAELTGKDSNVTASPTAPACPSDKPAPVQKPPSSG 120
QKAEELVKDNELLPPPSPSLGSFDPLAELTGKDSNVTASPTAPACPSDKPAPVQKPPSSG
Sbjct: 61 QKAEELVKDNELLPPPSPSLGSFDPLAELTGKDSNVTASPTAPACPSDKPAPVQKPPSSG 120
Query: 121 TSSEFEVVTPEEQNSPESSSHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQL 180
TSSEFEVVTPEEQNSPESSSHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQL
Sbjct: 121 TSSEFEVVTPEEQNSPESSSHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQL 180
Query: 181 FTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERL 240
FTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERL
Sbjct: 181 FTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERL 240
Query: 241 REENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAE 300
REENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAE
Sbjct: 241 REENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAE 300
Query: 301 KKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQ 360
KKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQ
Sbjct: 301 KKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQ 360
Query: 361 RDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLN 420
RDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLN
Sbjct: 361 RDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLN 420
Query: 421 KALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDR 480
KALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDR
Sbjct: 421 KALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDR 480
Query: 481 ERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGERYHVEPH 540
ERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGERYHVEPH
Sbjct: 481 ERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGERYHVEPH 540
Query: 541 PEHLCGAYPYAYPPMPAMVPHHGFEDWSQIRYPPPPMAMEHPPPLPNSRLFHLPEYTWRL 600
PEHLCGAYPYAYPPMPAMVPHHGFEDWSQIRYPPPPMAMEHPPPLPNSRLFHLPEYTWRL
Sbjct: 541 PEHLCGAYPYAYPPMPAMVPHHGFEDWSQIRYPPPPMAMEHPPPLPNSRLFHLPEYTWRL 600
Query: 601 PCGGVRNPNQSSQVMDPPTARPTEPESPKNDREGPQ 636
PCGGVRNPNQSSQVMDPPTARPTEPESPKNDREGPQ
Sbjct: 601 PCGGVRNPNQSSQVMDPPTARPTEPESPKNDREGPQ 636
>gi|192807309 TNFAIP3 interacting protein 3 [Homo sapiens]
Length = 325
Score = 173 bits (439), Expect = 4e-43
Identities = 98/250 (39%), Positives = 164/250 (65%), Gaps = 12/250 (4%)
Query: 296 LGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAE 355
+ + E+K++ LE+QR ELLEVN+QWDQ FRSMK+ YE+K+ EL+ KL ++ ++ E +
Sbjct: 33 MNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKD 92
Query: 356 ------REQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQR 409
++ +QR+ DR+ L + +++ EE +KE+L E EL+++ K L+ + + +++
Sbjct: 93 PHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEK 152
Query: 410 EYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIF 469
E+ E EI+RLNKAL++AL+I+ S E +E+ T+ E+LKQQV+I+
Sbjct: 153 EHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVE-----FCHEEMRTEMEVLKQQVQIY 207
Query: 470 EEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFK-DEEKAREALRQQKRKA 528
EEDF++ERSDRER+N+EKEEL++ E Q+Q+ N+Q+KA + ++EK + L+Q
Sbjct: 208 EEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMYCPP 267
Query: 529 KASGERYHVE 538
G +H++
Sbjct: 268 CNCGLVFHLQ 277
>gi|192807305 TNFAIP3 interacting protein 3 [Homo sapiens]
Length = 325
Score = 173 bits (439), Expect = 4e-43
Identities = 98/250 (39%), Positives = 164/250 (65%), Gaps = 12/250 (4%)
Query: 296 LGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAE 355
+ + E+K++ LE+QR ELLEVN+QWDQ FRSMK+ YE+K+ EL+ KL ++ ++ E +
Sbjct: 33 MNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKD 92
Query: 356 ------REQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQR 409
++ +QR+ DR+ L + +++ EE +KE+L E EL+++ K L+ + + +++
Sbjct: 93 PHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEK 152
Query: 410 EYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIF 469
E+ E EI+RLNKAL++AL+I+ S E +E+ T+ E+LKQQV+I+
Sbjct: 153 EHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVE-----FCHEEMRTEMEVLKQQVQIY 207
Query: 470 EEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFK-DEEKAREALRQQKRKA 528
EEDF++ERSDRER+N+EKEEL++ E Q+Q+ N+Q+KA + ++EK + L+Q
Sbjct: 208 EEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMYCPP 267
Query: 529 KASGERYHVE 538
G +H++
Sbjct: 268 CNCGLVFHLQ 277
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 78.2 bits (191), Expect = 2e-14
Identities = 82/338 (24%), Positives = 164/338 (48%), Gaps = 25/338 (7%)
Query: 210 TLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELK-KLLMSNGNKEGASGRPGSPK 268
T E+L KE +AL +L + E L+E+N EL+ KL + K K
Sbjct: 190 TYIEKLTKERDALSLELYRNTI----TDEELKEKNAELQEKLRLVESEKSEIQLNVKDLK 245
Query: 269 MEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELL---EVNKQWDQHFR 325
+ + + QQQ V A ++ + + +A+ + ++ E + LL + K W Q +
Sbjct: 246 RKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEK 305
Query: 326 SMKQQYEQKITELRQKLADLQKQVTDLEA---EREQKQRDFDRKLLLAKSKI-EMEETDK 381
+Q E+K+ E K+ + ++++ E E+E+K R+ + K+ + KI E EE +
Sbjct: 306 IQEQ--EEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIR 363
Query: 382 EQ---LTAEAKELRQKVKYLQDQLSPLTRQRE-YQEKEIQRLNKALEEALSIQTPPSSPP 437
EQ + + +++R++ + +Q+Q + RQ E +E+E +R K + ++
Sbjct: 364 EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEK-- 421
Query: 438 TAFGSPEGAGALLRKQELVTQ-NELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEK 496
E + R++E + + E+++ Q + E ++ + + E+M E++E++++Q EK
Sbjct: 422 ----IREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEK 477
Query: 497 LQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGER 534
+Q Q + Q K K EEK E + R+ + E+
Sbjct: 478 IQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQ 515
Score = 67.4 bits (163), Expect = 4e-11
Identities = 77/382 (20%), Positives = 179/382 (46%), Gaps = 53/382 (13%)
Query: 176 DHG-QLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRD 234
DH ++ T++ ++ E + L+ ++++N E+L+++N L+ KL ++
Sbjct: 183 DHAVRMGTYIEKLTKERDALSLELYRNTITD-------EELKEKNAELQEKLRLVESEKS 235
Query: 235 QAAERLRE--ENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPE 292
+ +++ LE +LL+ + + R G + K ++ +
Sbjct: 236 EIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQ 295
Query: 293 VVALGAAEKKV-----KMLEQQRSELLEVNKQWDQHFRSMKQQ------------YEQKI 335
+ E+K+ KM EQ+ + K W Q + +Q+ E+KI
Sbjct: 296 EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKI 355
Query: 336 TELRQKLADLQKQVTDLEA---EREQKQRDFDRKLLLAKSKI-EMEETDKEQLTAEAKEL 391
E +K+ + ++++ E E+++K ++ + ++ + KI E EE +E++ + K++
Sbjct: 356 REQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKM 415
Query: 392 RQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLR 451
R++ + +++Q + RQ E + +E++ + + EE L + E + R
Sbjct: 416 REQDEKIREQEEEMWRQEE-KIRELEEMMQDQEEKLR-EVEEKMQEEEEKMQEQEEKIQR 473
Query: 452 KQELVTQNE--------LLKQQVKIFEEDFQRERSDR------ERMNEEKEELKKQVEKL 497
++E + + E LLKQ+ KI+E++ + R + E+M E++E++++Q EK+
Sbjct: 474 QEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKM 533
Query: 498 QAQVTLSNAQLKAFKDEEKARE 519
+ Q +++ ++ EEK +E
Sbjct: 534 REQ------EVRLWQQEEKMQE 549
Score = 58.9 bits (141), Expect = 1e-08
Identities = 76/328 (23%), Positives = 155/328 (47%), Gaps = 37/328 (11%)
Query: 208 LQTLCEQLRKENEALKAKLDKGLEQRD-------QAAERL--REENLELKKLLMSNGNKE 258
LQ ++L KE +++ AKL +E+ + Q E++ +EE ++ ++ M ++
Sbjct: 260 LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMC---EQ 316
Query: 259 GASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNK 318
R KM +K +++ K + E+K++ E++ E E K
Sbjct: 317 ELKIREQEEKMWRQEEKMHEQEEKIREQEDK------MWRQEEKIREQEEKIREQEE--K 368
Query: 319 QWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEE 378
W Q + +Q ++KI E +++ ++++ + E +R++K ++K+ KI +E
Sbjct: 369 MWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 379 TDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPT 438
E++ + +++R+ + +QDQ L RE +EK + K E+ IQ
Sbjct: 427 ---EEMWRQEEKIRELEEMMQDQEEKL---REVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480
Query: 439 AFGSPEGAGALLRKQELVTQNE--LLKQQVKIFEEDF----QRERSDR--ERMNEEKEEL 490
LL+++E + + E + +Q+ K++E++ Q E+ R E+M E++ L
Sbjct: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540
Query: 491 KKQVEKLQAQ-VTLSNAQLKAFKDEEKA 517
+Q EK+Q Q V L + + K +KA
Sbjct: 541 WQQEEKMQEQEVRLQELEERLGKLGQKA 568
Score = 49.7 bits (117), Expect = 8e-06
Identities = 57/297 (19%), Positives = 140/297 (47%), Gaps = 22/297 (7%)
Query: 193 RLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQA---AERLREENLELKK 249
R K+H+ E++ ++ +++ ++ E ++ + +K EQ ++ E++RE++ ++++
Sbjct: 329 RQEEKMHEQEEK---IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQE 385
Query: 250 LLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQ- 308
+E + E ++ ++Q + E + E+K++ LE+
Sbjct: 386 QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE---MWRQEEKIRELEEM 442
Query: 309 ---QRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDR 365
Q +L EV ++ + M++Q E+KI +K+ + +++ E +Q+++ +++
Sbjct: 443 MQDQEEKLREVEEKMQEEEEKMQEQ-EEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501
Query: 366 KLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEE 425
+ + + + +M E +++ E K RQ+ K + ++ ++ + QE+E++ + LEE
Sbjct: 502 EEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRL--QELEE 559
Query: 426 ALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRER 482
L G GAG Q L T +L+ ++K E +++ D R
Sbjct: 560 RLG---KLGQKAELLG---GAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 75.5 bits (184), Expect = 1e-13
Identities = 81/338 (23%), Positives = 163/338 (48%), Gaps = 25/338 (7%)
Query: 210 TLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELK-KLLMSNGNKEGASGRPGSPK 268
T E+L KE +A +L + E L+E+N EL+ KL + K K
Sbjct: 190 TYIEKLTKERDAPSLELYRNTI----TDEELKEKNAELQEKLRLVESEKSEIQLNVKDLK 245
Query: 269 MEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELL---EVNKQWDQHFR 325
+ + + QQQ V A ++ + + +A+ + ++ E + LL + K W Q +
Sbjct: 246 RKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEK 305
Query: 326 SMKQQYEQKITELRQKLADLQKQVTDLEA---EREQKQRDFDRKLLLAKSKI-EMEETDK 381
+Q E+K+ E K+ + ++++ E E+E+K R+ + K+ + KI E EE +
Sbjct: 306 IQEQ--EEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIR 363
Query: 382 EQ---LTAEAKELRQKVKYLQDQLSPLTRQRE-YQEKEIQRLNKALEEALSIQTPPSSPP 437
EQ + + +++R++ + +Q+Q + RQ E +E+E +R K + ++
Sbjct: 364 EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEK-- 421
Query: 438 TAFGSPEGAGALLRKQELVTQ-NELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEK 496
E + R++E + + E+++ Q + E ++ + + E+M E++E++++Q EK
Sbjct: 422 ----IREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEK 477
Query: 497 LQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGER 534
+Q Q + Q K K EEK E + R+ + E+
Sbjct: 478 IQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQ 515
Score = 66.6 bits (161), Expect = 7e-11
Identities = 76/329 (23%), Positives = 159/329 (48%), Gaps = 56/329 (17%)
Query: 208 LQTLCEQLRKENEALKAKLDKGLEQRD-------QAAERL--REENLELKKLLMSNGNKE 258
LQ ++L KE +++ AKL +E+ + Q E++ +EE ++ ++ M ++
Sbjct: 260 LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMC---EQ 316
Query: 259 GASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNK 318
R KM +K +++ K + E+K++ E++ E E K
Sbjct: 317 ELKIREQEEKMWRQEEKMHEQEEKIREQEDK------MWRQEEKIREQEEKIREQEE--K 368
Query: 319 QWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEE 378
W Q + +Q ++KI E +++ ++++ + E +R++K ++K+ KI +E
Sbjct: 369 MWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 379 TDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPT 438
E++ + +++R+ + +QDQ L RE +EK + K E+ IQ
Sbjct: 427 ---EEMWRQEEKIRELEEMMQDQEEKL---REVEEKMQEEEEKMQEQEEKIQRQEEK--- 477
Query: 439 AFGSPEGAGALLRKQELVT--QNELLKQQVKIFEEDFQRERSDR------ERMNEEKEEL 490
+++QE T Q +LLKQ+ KI+E++ + R + E+M E++E++
Sbjct: 478 -----------IQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKM 526
Query: 491 KKQVEKLQAQVTLSNAQLKAFKDEEKARE 519
++Q EK++ Q +++ ++ EEK +E
Sbjct: 527 QRQEEKMREQ------EVRLWQQEEKMQE 549
Score = 49.7 bits (117), Expect = 8e-06
Identities = 57/297 (19%), Positives = 140/297 (47%), Gaps = 22/297 (7%)
Query: 193 RLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQA---AERLREENLELKK 249
R K+H+ E++ ++ +++ ++ E ++ + +K EQ ++ E++RE++ ++++
Sbjct: 329 RQEEKMHEQEEK---IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQE 385
Query: 250 LLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQ- 308
+E + E ++ ++Q + E + E+K++ LE+
Sbjct: 386 QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE---MWRQEEKIRELEEM 442
Query: 309 ---QRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDR 365
Q +L EV ++ + M++Q E+KI +K+ + +++ E +Q+++ +++
Sbjct: 443 MQDQEEKLREVEEKMQEEEEKMQEQ-EEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501
Query: 366 KLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEE 425
+ + + + +M E +++ E K RQ+ K + ++ ++ + QE+E++ + LEE
Sbjct: 502 EEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRL--QELEE 559
Query: 426 ALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRER 482
L G GAG Q L T +L+ ++K E +++ D R
Sbjct: 560 RLG---KLGQKAELLG---GAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 74.7 bits (182), Expect = 2e-13
Identities = 112/543 (20%), Positives = 227/543 (41%), Gaps = 76/543 (13%)
Query: 20 EASAAFERLVKENSRLKEKMQGIKMLGELLEESQMEATRLRQKAEELVKDNELLPPPSPS 79
E AA+++L K +RL++++ + + + +S + ++K ++L+ + + + S
Sbjct: 1403 EKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTI---SAK 1459
Query: 80 LGSFDPLAELTGKDSNVTASPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSPES- 138
AE ++ A A A + A QK + +F + +S +
Sbjct: 1460 YAEERDRAEAEAREKETKALSLARAL---EEAMEQKAELERLNKQFRTEMEDLMSSKDDV 1516
Query: 139 --SSHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNR--- 193
S H + L ++ + L+ LE L A E +L +L M +F R
Sbjct: 1517 GKSVHELEKSKRALEQQVEEMKTQLEELEDELQ--ATEDAKLRLEVNLQAMKAQFERDLQ 1574
Query: 194 -------------------LASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRD 234
+ +++ ++ S+ ++L + + L+A +D + RD
Sbjct: 1575 GRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRD 1634
Query: 235 QAAERLREENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVV 294
+A ++LR+ ++K + +E R ++ K+ ++ S+ A +
Sbjct: 1635 EAIKQLRKLQAQMKDCM-----RELDDTRASREEILAQAKENE--KKLKSMEAEMIQLQE 1687
Query: 295 ALGAAEKKVKMLEQQRSEL--------------LEVNKQWDQHFRSMKQQYEQKI--TEL 338
L AAE+ + +Q+R EL LE ++ + ++++ E++ TEL
Sbjct: 1688 ELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTEL 1747
Query: 339 ---RQKLADLQ-KQV-TDLEAEREQKQRD------FDRKLLLAKSKI-EMEETDKEQLTA 386
R K A+LQ Q+ TDL ER Q++ +R+ K K+ EME T K + A
Sbjct: 1748 INDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKA 1807
Query: 387 EAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGA 446
L K+ L++QL T++R+ K+++R K L++ L +
Sbjct: 1808 SITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADK 1867
Query: 447 GALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNA 506
+ KQ LK+Q++ EE+ QR + R ++ E E+ + + + +V+
Sbjct: 1868 ASTRLKQ--------LKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKN 1919
Query: 507 QLK 509
+L+
Sbjct: 1920 KLR 1922
Score = 69.7 bits (169), Expect = 8e-12
Identities = 85/397 (21%), Positives = 167/397 (42%), Gaps = 40/397 (10%)
Query: 162 QRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEA 221
++L+ +CAE + R+ + L H E R + C+ L+ E +
Sbjct: 887 EQLQAETELCAEAEELR------ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKK 940
Query: 222 LKA---KLDKGLEQRDQAAERLREENL----ELKKLLMSNGNKEGASGRPGSPKM----- 269
++ +L++ LE+ + A ++L+ E + +LKKL E + + K
Sbjct: 941 MQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDR 1000
Query: 270 --EGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSM 327
E T ++ S+ K + E++++ E+QR EL
Sbjct: 1001 IAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQEL-----------EKT 1049
Query: 328 KQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAE 387
+++ E T+L ++A+LQ Q+ +L+ + +K+ + L A +++E E K +
Sbjct: 1050 RRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEE----LQAALARVEEEAAQKNMALKK 1105
Query: 388 AKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAG 447
+EL ++ LQ+ L R EK+ + L + L EAL + + TA +
Sbjct: 1106 IRELESQISELQEDLESERASRNKAEKQKRDLGEEL-EALKTELEDTLDSTA---AQQEL 1161
Query: 448 ALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQ 507
R+QE+ + L+++ K E Q R + EE E +Q ++++A + +
Sbjct: 1162 RSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQT 1221
Query: 508 LKAFKDEEKAREALRQQKRKAKASGERYHVEPHPEHL 544
L+ + E A E + K + +R VE + L
Sbjct: 1222 LENERG-ELANEVKVLLQGKGDSEHKRKKVEAQLQEL 1257
Score = 53.9 bits (128), Expect = 4e-07
Identities = 100/509 (19%), Positives = 195/509 (38%), Gaps = 55/509 (10%)
Query: 26 ERLVKENSRLKEKMQGIKMLGELLEES-------QMEATRLRQKAEELVKDNELLPPPSP 78
ER + K+ Q I+ L E LEE Q+E K ++L ++ +L +
Sbjct: 929 ERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNC 988
Query: 79 SLGSFDPLAELTGKDSNVTASPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSPES 138
L L E + + T + T S A ++ + + E + EE+ E
Sbjct: 989 KLAKEKKLLE--DRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQEL 1046
Query: 139 SSHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKV 198
+ D L Q E + + +E + + A + N K+
Sbjct: 1047 EKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKI 1106
Query: 199 HKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKE 258
+ E + S +L+++ E+ +A +K +Q+ E L EL+ L S ++
Sbjct: 1107 RELESQIS-------ELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159
Query: 259 GASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNK 318
R + KK + +++A ++ E+ +K ++ +E LE K
Sbjct: 1160 EL--RSKREQEVNILKKTL--EEEAKTHEAQIQEM------RQKHSQAVEELAEQLEQTK 1209
Query: 319 QWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEE 378
+ + KQ E + R +LA+ K + + + E K++ + +L +++++
Sbjct: 1210 RVKANLEKAKQTLENE----RGELANEVKVLLQGKGDSEHKRKKVEAQL----QELQVKF 1261
Query: 379 TDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPT 438
+ E++ E + K++ D ++ L Q + + ++ + ALE L
Sbjct: 1262 NEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQL----------- 1310
Query: 439 AFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQ 498
+ LL+++ Q L ++K E++ R E E K L+KQ+ L
Sbjct: 1311 -----QDTQELLQEEN--RQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLH 1363
Query: 499 AQVTLSNAQLKAFKDEEKAREALRQQKRK 527
AQV K +D E + KRK
Sbjct: 1364 AQVA---DMKKKMEDSVGCLETAEEVKRK 1389
Score = 45.1 bits (105), Expect = 2e-04
Identities = 52/256 (20%), Positives = 115/256 (44%), Gaps = 54/256 (21%)
Query: 274 KKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQR-----SELLEVNKQWDQHFRSMK 328
+KA A +QQ +TA KV + AA K++ + R LL+V++Q ++
Sbjct: 796 RKAFAKRQQ-QLTAMKVLQRNC--AAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAK-- 850
Query: 329 QQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEA 388
E+++ ++R+K + ++T++E + Q L+ K +++ + + +L AEA
Sbjct: 851 ---EEELVKVREKQLAAENRLTEMETLQSQ--------LMAEKLQLQEQLQAETELCAEA 899
Query: 389 KELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGA 448
+ELR ++ + +L + E + +E +
Sbjct: 900 EELRARLTAKKQELEEICHDLEARVEEEEE------------------------------ 929
Query: 449 LLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKL-QAQVTLSNAQ 507
R Q L + + ++Q ++ EE + E S R+++ EK + +++KL + Q+ L +
Sbjct: 930 --RCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQN 987
Query: 508 LKAFKDEEKAREALRQ 523
K K+++ + + +
Sbjct: 988 CKLAKEKKLLEDRIAE 1003
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 74.3 bits (181), Expect = 3e-13
Identities = 77/371 (20%), Positives = 176/371 (47%), Gaps = 24/371 (6%)
Query: 183 HLGRMALEFN-RLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRD---QAAE 238
HLG+ + +L ++V +NE + Q E++ ++ E ++ +K EQ + + E
Sbjct: 269 HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328
Query: 239 RLREENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGA 298
++RE+ ++++ KE R E K + + +
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 388
Query: 299 AEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQ 358
E+K++ LE++ E ++ +Q ++ K + ++K E K+ ++++ E+E+
Sbjct: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR----EQEE 444
Query: 359 KQRDFDRKLLLAKSKI-EMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQ 417
K R+ ++K+ + KI E E+ +E+ E +E+ ++ + + +Q + RQ+E ++ +
Sbjct: 445 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQ-EEIWRQKEKMHEQEE 503
Query: 418 RLNKALEEALSIQTPPSSPPTAFGSPEGA-----GALLRKQELVTQNELLKQQVKIFEED 472
++ K E+ + E + ++E+ + E + +Q KI+EE+
Sbjct: 504 KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE 563
Query: 473 FQRERSDR-----ERMNEEKEELKKQVEKLQAQVTLSNAQ-LKAFKDEEKAR---EALRQ 523
++E+ D+ E++ E++E++ +Q EK++ Q Q K +K EEK R E +++
Sbjct: 564 KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQE 623
Query: 524 QKRKAKASGER 534
Q+ K + E+
Sbjct: 624 QEEKIREQEEK 634
Score = 68.6 bits (166), Expect = 2e-11
Identities = 108/482 (22%), Positives = 208/482 (43%), Gaps = 65/482 (13%)
Query: 93 DSNVTASPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSPESSSHANAMALGPLPR 152
D + +P+ SD +K ++GT+ E T +SPE A+ L R
Sbjct: 69 DHHPQTNPSVGTAASDTK---KKKINNGTNPE--TTTSGGCHSPEDEQKASHQHQEALRR 123
Query: 153 EDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMAL-----EFNRLASKVHKN------ 201
E L+ T+ + + Q+ + + A+ E L S++H +
Sbjct: 124 E-------LEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGE 176
Query: 202 -EQRTSILQT-------LCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELK-KLLM 252
EQ S + T E+L KE +AL +L + E L+E+N +L+ KL +
Sbjct: 177 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTI----TDEELKEKNAKLQEKLQL 232
Query: 253 SNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKM------- 305
K K + K + QQQ A + + + +A+ + ++
Sbjct: 233 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWN 292
Query: 306 -LEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEA---EREQKQR 361
L QQ+ E + ++ Q + Q+ E+KI E +K+ + ++++ E E+E+K R
Sbjct: 293 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 352
Query: 362 DFDRKLLLAKSKIEMEET---DKEQLTAEAKEL----RQKVKYLQDQLSPLTRQREYQEK 414
+ + + K+ +E +KE+ +E+ +K++ L++++ + RE +EK
Sbjct: 353 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 412
Query: 415 EIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQE--LVTQNELLKQQVKIFEED 472
++ + + E Q + +R+QE + Q E + +Q KI EE+
Sbjct: 413 --RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 470
Query: 473 FQRERSDRERMNE---EKEELKKQVEKLQAQ-VTLSNAQLKAFKDEEKAR---EALRQQK 525
++E+ + R E E+EE+ +Q EK+ Q + + K ++ EEK R E +R+Q+
Sbjct: 471 KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQE 530
Query: 526 RK 527
K
Sbjct: 531 EK 532
Score = 59.7 bits (143), Expect = 8e-09
Identities = 75/359 (20%), Positives = 161/359 (44%), Gaps = 23/359 (6%)
Query: 186 RMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDK--GLEQRDQAAERLREE 243
+M + + K K ++ ++ E++R++ E + K +K LE++ E++RE+
Sbjct: 350 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 409
Query: 244 NL----ELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAA 299
E K ++ A K+ +K +++ K+ E +
Sbjct: 410 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 469
Query: 300 EKKVKMLEQQRSE--LLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAERE 357
EK+ + E R E + E + W Q + +Q E+KI + +K+ ++++ E+E
Sbjct: 470 EKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ--EEKIRKQEEKVWRQEEKIR----EQE 523
Query: 358 QKQRDFDRKLLLAKSKI-EMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEI 416
+K R+ + K+ + KI E EE +E+ +E + + Q+Q + RQ E ++
Sbjct: 524 EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQE 583
Query: 417 QRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQE--LVTQNELLKQQVKIFEEDFQ 474
+++ + E+ + E +R+QE + Q E +++Q + E +
Sbjct: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEK---IREQEEKIQEQEEKIREQEEKIREQEE 640
Query: 475 RERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGE 533
+ E+M E++E++ +Q EK+Q Q Q + +++EK +R+Q+ K + E
Sbjct: 641 MTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK---KIREQEEKIREQEE 696
Score = 57.0 bits (136), Expect = 5e-08
Identities = 68/332 (20%), Positives = 165/332 (49%), Gaps = 42/332 (12%)
Query: 193 RLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRD--QAAERLREENLELKKL 250
R K+H+ E+ E+ R+E E + + +K EQ + + E++ E+ +++K
Sbjct: 455 RQEEKIHEQEKIRE------EEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ 508
Query: 251 LMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQR 310
+E K+ +K +++ K+ E + E+K+ ++
Sbjct: 509 EEKVWRQE--------EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKM----HEQ 556
Query: 311 SELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLA 370
++ E K+ +Q + +Q E+KI E +K+ ++++ E+E+K+++ + K+
Sbjct: 557 EKIWEEEKRQEQEDKMWRQ--EEKIREQEEKVWRQEEKIR----EQEEKRQEQEEKMWKQ 610
Query: 371 KSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQ 430
+ KI +E E++ + +++R++ + +++Q +T+++E EK ++ K E+ +Q
Sbjct: 611 EEKIREQE---EKIQEQEEKIREQEEKIREQ-EEMTQEQE--EKMGEQEEKMCEQEEKMQ 664
Query: 431 TPPSSPPTAFGSPEGAGALLRKQE--LVTQNELLKQQVKIFEEDFQRERSDRERMNEEKE 488
T + E +R+QE + Q E +++Q ++ +E ++ E+M E++E
Sbjct: 665 ---EQEETMWRQEEK----IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 717
Query: 489 ELKKQVEKLQAQ-VTLSNAQLKAFKDEEKARE 519
++++Q EK++ Q + +++ + EEK +E
Sbjct: 718 KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 72.8 bits (177), Expect = 9e-13
Identities = 99/401 (24%), Positives = 179/401 (44%), Gaps = 58/401 (14%)
Query: 163 RLETTLSVCAEEPDHG-QLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEA 221
RL+ L + DH Q+ ++L + +F++L ++ R + + E +E E
Sbjct: 1424 RLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKET 1483
Query: 222 LKAKLDKGLEQRDQAAERLREENLELK---KLLMSNGNKEGASGRPGSPKMEGTGKKAVA 278
L + LE+ +A E +N +L+ + LMS+ + G + + K A
Sbjct: 1484 KALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKN-------VHELEKSKRA 1536
Query: 279 GQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKIT-- 336
+QQ ++ E+ E +++ E + L EVN Q +MK Q+E+ +
Sbjct: 1537 LEQQVEEMRTQLEEL------EDELQATEDAKLRL-EVNMQ------AMKAQFERDLQTR 1583
Query: 337 --ELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLA-KSKIEMEETDKEQLTAEAKELRQ 393
+ +K L KQV +LEAE E +++ R L +A K K+E++ D E A + R
Sbjct: 1584 DEQNEEKKRLLIKQVRELEAELEDERKQ--RALAVASKKKMEIDLKDLEAQIEAANKARD 1641
Query: 394 KV----KYLQDQLSPLTRQREY----------QEKEIQRLNKALE-EALSIQTPPSSPPT 438
+V + LQ Q+ R+ E Q KE ++ K+LE E L +Q +S
Sbjct: 1642 EVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSER 1701
Query: 439 AFGSPEG---------AGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEE 489
A E + K L+ + L+ ++ EE+ + E+S+ E +N+ +
Sbjct: 1702 ARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRK 1761
Query: 490 LKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKA 530
QV+ L A++ A+ A + + AR+ L +Q ++ KA
Sbjct: 1762 TTLQVDTLNAELA---AERSAAQKSDNARQQLERQNKELKA 1799
Score = 70.9 bits (172), Expect = 3e-12
Identities = 86/399 (21%), Positives = 176/399 (44%), Gaps = 28/399 (7%)
Query: 153 EDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKVHKNEQRTSILQTLC 212
E+ N++ + ET L AEE +L + + L S+V + E+R ILQ
Sbjct: 887 EEKNILAEQLQAETELFAEAEEM-RARLAAKKQELEEILHDLESRVEEEEERNQILQNEK 945
Query: 213 EQLRKENEALKAKLDK--GLEQRDQAAERLRE---ENLELKKLLMSNGNKEGASGRPGSP 267
++++ + L+ +LD+ G Q+ Q + E + +E + LL+ + N + +
Sbjct: 946 KKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLME 1005
Query: 268 KMEGTGKKAVAGQQQASVTAGKV--PEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFR 325
+A +++ + K+ + V + E+++K E+ R EL
Sbjct: 1006 DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQEL-----------E 1054
Query: 326 SMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLT 385
K++ + + T+L+ ++A+LQ Q+ +L+ + +K+ + L ++ + E K
Sbjct: 1055 KAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGAL----ARGDDETLHKNNAL 1110
Query: 386 AEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEG 445
+EL+ ++ LQ+ R EK+ + L++ L EAL + + TA +
Sbjct: 1111 KVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEEL-EALKTELEDTLDTTA---AQQ 1166
Query: 446 AGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSN 505
R+QE+ + L+++ K E Q R EE E +Q ++ +A + N
Sbjct: 1167 ELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLE-KN 1225
Query: 506 AQLKAFKDEEKAREALRQQKRKAKASGERYHVEPHPEHL 544
Q ++E A E Q+ KA++ +R ++ + L
Sbjct: 1226 KQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQEL 1264
Score = 64.7 bits (156), Expect = 2e-10
Identities = 96/389 (24%), Positives = 161/389 (41%), Gaps = 50/389 (12%)
Query: 194 LASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMS 253
LA K K + + TL E+ K+ AK LE + Q + L +E K L S
Sbjct: 1278 LAEKASKLQNELDNVSTLLEEAEKKGIKF-AKDAASLESQLQDTQELLQEETRQKLNLSS 1336
Query: 254 N-------GNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPE----VVALGAAEKK 302
N + K+ +A Q Q + T KV + + +L A+KK
Sbjct: 1337 RIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKK 1396
Query: 303 VKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRD 362
+ + S+ LE K + +Q++ +L L D Q+QV + E+KQ+
Sbjct: 1397 LLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDL-DHQRQVA---SNLEKKQKK 1452
Query: 363 FDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKA 422
FD+ L KS ++++ AEA+E K L L +E E++ ++L
Sbjct: 1453 FDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRAD 1512
Query: 423 LEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEE----------- 471
+E+ +S + + A + +E+ TQ E L+ +++ E+
Sbjct: 1513 MEDLMSSKDDVGKNVHELEKSKRA-LEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQA 1571
Query: 472 ---DFQRERSDRERMNEEKEELK-KQVEKLQAQV-------TLSNAQLKA----FKDEE- 515
F+R+ R+ NEEK+ L KQV +L+A++ L+ A K KD E
Sbjct: 1572 MKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEA 1631
Query: 516 ------KAREALRQQKRKAKASGERYHVE 538
KAR+ + +Q RK +A + Y E
Sbjct: 1632 QIEAANKARDEVIKQLRKLQAQMKDYQRE 1660
Score = 58.2 bits (139), Expect = 2e-08
Identities = 106/534 (19%), Positives = 223/534 (41%), Gaps = 65/534 (12%)
Query: 20 EASAAFERLVKENSRLKEKMQGIKMLGELLEESQMEATRLRQKAEELVKDNELLPPPSPS 79
E + A+++L K +RL++++ + + + + + ++K ++L+ + + + S
Sbjct: 1410 EKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSI---SAR 1466
Query: 80 LGSFDPLAELTGKDSNVTASPTAPACPSDKPAPVQ-KPPSSGTSSEFEVVTPEEQNSPES 138
AE ++ A A A A + + + ++ E + + + ++
Sbjct: 1467 YAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKN 1526
Query: 139 SSHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNR-LASK 197
H + L ++ + L+ LE L A E +L ++ M +F R L ++
Sbjct: 1527 V-HELEKSKRALEQQVEEMRTQLEELEDELQ--ATEDAKLRLEVNMQAMKAQFERDLQTR 1583
Query: 198 VHKNEQRTSILQTLCEQLRKENE----------ALKAKLD---KGLEQRDQAAERLREEN 244
+NE++ +L +L E E A K K++ K LE + +AA + R+E
Sbjct: 1584 DEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEV 1643
Query: 245 L-ELKKLL--MSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEK 301
+ +L+KL M + +E R ++ K++ + ++ E +A ++E+
Sbjct: 1644 IKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELA--SSER 1701
Query: 302 KVKMLEQQRSELLEV---NKQWDQHFRSMKQQYEQKITELRQKLADLQKQV--------- 349
+ EQ+R EL + + K++ E +I +L ++L + Q +
Sbjct: 1702 ARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRK 1761
Query: 350 ---------TDLEAEREQKQRD------FDRKLLLAKSKI-EMEETDKEQLTAEAKELRQ 393
+L AER Q+ +R+ K+K+ E+E K + A L
Sbjct: 1762 TTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEA 1821
Query: 394 KVKYLQDQLSPLTRQREYQEKEIQRLNKALEEA-LSIQTPPSSPPTAFGSPEGAGALLRK 452
K+ L++QL ++R K ++R K L+E + ++ E A A +++
Sbjct: 1822 KIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQ 1881
Query: 453 QELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQV-TLSN 505
LK+Q++ EE+ R + R ++ E ++ + E L +V TL N
Sbjct: 1882 ---------LKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKN 1926
Score = 55.1 bits (131), Expect = 2e-07
Identities = 54/246 (21%), Positives = 115/246 (46%), Gaps = 23/246 (9%)
Query: 303 VKMLEQQRSELLEVNK-QWDQHFRSMKQ-----QYEQKITELRQKLADLQKQVTDLEAER 356
+K+L++ + L++ QW + F +K + E+++ ++L ++++ T +E E
Sbjct: 816 LKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGEL 875
Query: 357 EQKQRDFDRKLLLAKSKIEMEETDKE-QLTAEAKELRQKVKYLQDQLSPLTRQREYQEKE 415
E+ +R + LL + I E+ E +L AEA+E+R ++ + +L + E + +E
Sbjct: 876 EEMERKHQQ--LLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEE 933
Query: 416 IQRLNKALE-EALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQ 474
+ N+ L+ E +Q EGA L+ +++ + ++ K + +I + Q
Sbjct: 934 EEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQ 993
Query: 475 RERSDRER-------------MNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREAL 521
+ +E+ + EE+E+ K + Q + + + K EEK R+ L
Sbjct: 994 NSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQEL 1053
Query: 522 RQQKRK 527
+ KRK
Sbjct: 1054 EKAKRK 1059
Score = 34.7 bits (78), Expect = 0.28
Identities = 22/94 (23%), Positives = 49/94 (52%), Gaps = 15/94 (15%)
Query: 451 RKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKA 510
+ Q+L+ + +L +Q++ E F R R+ +K+EL++ + L+++V
Sbjct: 881 KHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRV--------- 931
Query: 511 FKDEEKAREALRQQKRKAKASGERYHVEPHPEHL 544
++EE+ + L+ +K+K +A H++ E L
Sbjct: 932 -EEEEERNQILQNEKKKMQA-----HIQDLEEQL 959
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 72.8 bits (177), Expect = 9e-13
Identities = 105/516 (20%), Positives = 220/516 (42%), Gaps = 54/516 (10%)
Query: 28 LVKENSRLKEKMQGIKMLGELLEESQMEATRLRQKAEELVKDNELLPPPSPSLGSFDPLA 87
L++ + L+E++ + G+ + E + E +L+ K +L D + L + +
Sbjct: 359 LIETKAMLEEQLTAARARGDKVHELEKENLQLKSKLHDLELDRDTDKKRIEELLEENMVL 418
Query: 88 ELTGKDS-NVTASPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSPESSSHANAMA 146
E+ K S N +A K A + +S S FE+ + +
Sbjct: 419 EIAQKQSMNESAHLGWELEQLSKNADLSD--ASRKSFVFEL------------NECASSR 464
Query: 147 LGPLPREDGNLMLHLQRLETTLSVCAEEP-DHGQLFTHLGRMALEFNRLASKVHKNEQRT 205
+ L +E+ +L +Q L V E G+L +++ + +L +++ + +Q
Sbjct: 465 ILKLEKENQSLQSTIQGLRDASLVLEESGLKCGELEKENHQLSKKIEKLQTQLEREKQSN 524
Query: 206 SILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRPG 265
L+TL E+L +E E L++ ++ + + + L +E L + + S + S
Sbjct: 525 QDLETLSEELIREKEQLQSDMETLKADKARQIKDLEQEKDHLNRAMWSLRERSQVS---S 581
Query: 266 SPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFR 325
+M+ K+ A Q + GK+ ++ E + + L + + E ++ ++ R
Sbjct: 582 EARMKDVEKENKALHQTVTEANGKLSQL------EFEKRQLHRDLEQAKEKGERAEKLER 635
Query: 326 SMKQQYEQ------KITELR---QKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEM 376
+++ E+ K+T L +K+ L+ + L+ E ++ D L ++E
Sbjct: 636 ELQRLQEENGRLARKVTSLETATEKVEALEHESQGLQLENRTLRKSLD-TLQNVSLQLEG 694
Query: 377 EETDKEQLTAEAKELRQKV---KYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPP 433
E D +QL AE ELR+ V ++ +L+ + R+ + E+E + L K ++ ++
Sbjct: 695 LERDNKQLDAENLELRRLVETMRFTSTKLAQMERENQQLEREKEELRKNVDLLKAL---- 750
Query: 434 SSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQ 493
+ L Q + +N L+Q ++ Q S+ + E++ L++
Sbjct: 751 --------GKKSERLELSYQSVSAENLRLQQSLESSSHKTQTLESELGELEAERQALRRD 802
Query: 494 VEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAK 529
+E L+ L+NAQL+ + + KA E Q K K
Sbjct: 803 LEALR----LANAQLEGAEKDRKALEQEVAQLEKDK 834
Score = 72.4 bits (176), Expect = 1e-12
Identities = 124/518 (23%), Positives = 213/518 (41%), Gaps = 81/518 (15%)
Query: 21 ASAAFERLVKENSRLKEKMQGIKMLGELLEESQMEATRLRQKAEELVKDNELLPPP---- 76
AS+ +L KEN L+ +QG++ +LEES ++ L ++ +L K E L
Sbjct: 461 ASSRILKLEKENQSLQSTIQGLRDASLVLEESGLKCGELEKENHQLSKKIEKLQTQLERE 520
Query: 77 SPSLGSFDPLAE--LTGKDSNVTASPTAPACPSDKPAPVQKPPS------------SGTS 122
S + L+E + K+ + T A + + +++ S S
Sbjct: 521 KQSNQDLETLSEELIREKEQLQSDMETLKADKARQIKDLEQEKDHLNRAMWSLRERSQVS 580
Query: 123 SEFEVVTPEEQNSP--ESSSHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQ- 179
SE + E++N ++ + AN L ++L L E+ + +
Sbjct: 581 SEARMKDVEKENKALHQTVTEANGKL--------SQLEFEKRQLHRDLEQAKEKGERAEK 632
Query: 180 LFTHLGRMALEFNRLASKVHKNEQRTSILQTL---CEQLRKENEALKAKLDK------GL 230
L L R+ E RLA KV E T ++ L + L+ EN L+ LD L
Sbjct: 633 LERELQRLQEENGRLARKVTSLETATEKVEALEHESQGLQLENRTLRKSLDTLQNVSLQL 692
Query: 231 EQRDQAAERLREENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKV 290
E ++ ++L ENLEL++L+ + R S K+ ++ +++ V
Sbjct: 693 EGLERDNKQLDAENLELRRLVETM--------RFTSTKLAQMERENQQLEREKEELRKNV 744
Query: 291 PEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVT 350
+ ALG KK + LE + N + Q S + + +EL + A+ Q
Sbjct: 745 DLLKALG---KKSERLELSYQSVSAENLRLQQSLESSSHKTQTLESELGELEAERQALRR 801
Query: 351 DLEAER----EQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLT 406
DLEA R + + + DRK L + ++ E DK+ L EAK L Q+V+ L T
Sbjct: 802 DLEALRLANAQLEGAEKDRKAL--EQEVAQLEKDKKLLEKEAKRLWQQVELKDAVLDDST 859
Query: 407 RQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQV 466
+ EKE + L+K L + AG L +EL N L +QV
Sbjct: 860 AKLSAVEKESRALDKELARC----------------RDAAGKL---KELEKDNRDLTKQV 900
Query: 467 KI-------FEEDFQRERSDRERMNEEKEELKKQVEKL 497
+ ED E+ ++++ E ++L +++EK+
Sbjct: 901 TVHARTLTTLREDLVLEKLKSQQLSSELDKLSQELEKV 938
Score = 55.5 bits (132), Expect = 2e-07
Identities = 108/530 (20%), Positives = 204/530 (38%), Gaps = 45/530 (8%)
Query: 28 LVKENSRLKEKMQGIKMLGELLEESQMEATRLRQKAEELVKDNELLPPPSPSLGSFDPLA 87
L E L+ ++ +++ LE ++ + L Q+ +L KD +LL + L L
Sbjct: 792 LEAERQALRRDLEALRLANAQLEGAEKDRKALEQEVAQLEKDKKLLEKEAKRLWQQVELK 851
Query: 88 ELTGKDSNVTASPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSPESSSHANAMAL 147
+ DS S + + ++G E E ++ +A L
Sbjct: 852 DAVLDDSTAKLSAVEKESRALDKELARCRDAAGKLKELE----KDNRDLTKQVTVHARTL 907
Query: 148 GPLPREDGNL-MLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKVHKNEQRTS 206
L RED L L Q+L + L ++E + L L L ++ +
Sbjct: 908 TTL-REDLVLEKLKSQQLSSELDKLSQELEKVGLNREL--------LLQEDDSGSDTKYK 958
Query: 207 ILQTLCEQLRKENEALKAK----LDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASG 262
IL+ E K A+K + L+ +E++ +L E LKK + +G
Sbjct: 959 ILEGRNESALKTTLAMKEEKIVLLEAQMEEKASLNRQLESELQMLKKECETLRQNQGEGQ 1018
Query: 263 RPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELL---EVNKQ 319
+ GK A + Q + + G + L + + LE+ + L ++ K+
Sbjct: 1019 HLQNSFKHPAGKTAASHQGKEAWGPGHKEATMELLRVKDRAIELERNNAALQAEKQLLKE 1078
Query: 320 WDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRD----------FDRKLLL 369
QH + + +I L+++ A LQ+ T L+ + + Q + + L
Sbjct: 1079 QLQHLETQNVTFSSQILTLQKQSAFLQEHNTTLQTQTAKLQVENSTLSSQSAALTAQYTL 1138
Query: 370 AKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLN------KAL 423
++ +ET+ E L + ++L + L L E Q E + L K L
Sbjct: 1139 LQNHHTAKETENESLQRQQEQLTAAYEALLQDHEHLGTLHERQSAEYEALIRQHSCLKTL 1198
Query: 424 EEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVK---IFEEDFQRERSDR 480
L ++ A R++ L T+ E L+Q+ + + + QR R +
Sbjct: 1199 HRNLELEHKELGERHGDMLKRKAELEEREKVLTTEREALQQEQRTNALAMGENQRLRGEL 1258
Query: 481 ERMNEEKEELKKQVEKLQA-----QVTLSNAQLKAFKDEEKAREALRQQK 525
+R+N +LK + E+L A + +L+NAQL+ + + + E Q +
Sbjct: 1259 DRVNFLHHQLKGEYEELHAHTKELKTSLNNAQLELNRWQARFDELKEQHQ 1308
Score = 49.7 bits (117), Expect = 8e-06
Identities = 100/447 (22%), Positives = 173/447 (38%), Gaps = 76/447 (17%)
Query: 152 REDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFN--RLASKVHKNEQRTSILQ 209
RE N ++RLE L+ C E+ + E N + +K EQ T+
Sbjct: 319 REKAN---RVERLELELTRCKEKLHDVDFYKARMEELREDNIILIETKAMLEEQLTAARA 375
Query: 210 T--LCEQLRKENEALKAKLDKGLEQRD---QAAERLREENLELK---------------- 248
+L KEN LK+KL RD + E L EEN+ L+
Sbjct: 376 RGDKVHELEKENLQLKSKLHDLELDRDTDKKRIEELLEENMVLEIAQKQSMNESAHLGWE 435
Query: 249 -KLLMSNGNKEGASGRPGSPKMEGTGKKAV-----AGQQQASVTAGKVPEVVALGAAEKK 302
+ L N + AS + ++ + Q S G + L + K
Sbjct: 436 LEQLSKNADLSDASRKSFVFELNECASSRILKLEKENQSLQSTIQGLRDASLVLEESGLK 495
Query: 303 VKMLEQQRSEL----------LEVNKQWDQHFRSMKQQY----EQKITELRQKLADLQKQ 348
LE++ +L LE KQ +Q ++ ++ EQ +++ AD +Q
Sbjct: 496 CGELEKENHQLSKKIEKLQTQLEREKQSNQDLETLSEELIREKEQLQSDMETLKADKARQ 555
Query: 349 VTDLEAEREQKQRDF----DRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSP 404
+ DLE E++ R +R + ++++++ E + + L E K+ L+ +
Sbjct: 556 IKDLEQEKDHLNRAMWSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQ 615
Query: 405 LTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALL-----RKQELVTQN 459
L R E +++ +R K E +Q S E A + Q L +N
Sbjct: 616 LHRDLEQAKEKGERAEKLERELQRLQEENGRLARKVTSLETATEKVEALEHESQGLQLEN 675
Query: 460 ELLK------QQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQ------AQVTLSNAQ 507
L+ Q V + E +R D ++++ E EL++ VE ++ AQ+ N Q
Sbjct: 676 RTLRKSLDTLQNVSLQLEGLER---DNKQLDAENLELRRLVETMRFTSTKLAQMERENQQ 732
Query: 508 LKAFKDEEKAREALRQQKRKAKASGER 534
L E+ +E LR+ KA G++
Sbjct: 733 L------EREKEELRKNVDLLKALGKK 753
Score = 40.0 bits (92), Expect = 0.007
Identities = 128/617 (20%), Positives = 232/617 (37%), Gaps = 113/617 (18%)
Query: 26 ERLVKENSRLKEKMQGIKMLGELLEESQMEATRLRQKAEELVKDNELLPPPSPSLGSFD- 84
+RL +EN RL K+ ++ E +E + E+ L+ + L K + L S L +
Sbjct: 638 QRLQEENGRLARKVTSLETATEKVEALEHESQGLQLENRTLRKSLDTLQNVSLQLEGLER 697
Query: 85 PLAELTGKDSNVTASPTAPACPSDKPAPVQKPPSS------------------GTSSE-- 124
+L ++ + S K A +++ G SE
Sbjct: 698 DNKQLDAENLELRRLVETMRFTSTKLAQMERENQQLEREKEELRKNVDLLKALGKKSERL 757
Query: 125 ---FEVVTPEE---QNSPESSSHANAMA---LGPLPREDGNLMLHLQRLE-TTLSVCAEE 174
++ V+ E Q S ESSSH LG L E L L+ L + E
Sbjct: 758 ELSYQSVSAENLRLQQSLESSSHKTQTLESELGELEAERQALRRDLEALRLANAQLEGAE 817
Query: 175 PDHGQLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAK---LDKGLE 231
D L + ++ + L + + Q+ + + + + A++ + LDK L
Sbjct: 818 KDRKALEQEVAQLEKDKKLLEKEAKRLWQQVELKDAVLDDSTAKLSAVEKESRALDKELA 877
Query: 232 QRDQAAERLRE-----------------------ENLELKKLLMSNGNKEGASGRPGSPK 268
+ AA +L+E E+L L+KL + E K
Sbjct: 878 RCRDAAGKLKELEKDNRDLTKQVTVHARTLTTLREDLVLEKLKSQQLSSELDKLSQELEK 937
Query: 269 MEGTGKKAVAGQQQASVTAGKVPE-------VVALGAAEKKVKMLEQQRSELLEVNKQWD 321
+ + + S T K+ E L E+K+ +LE Q E +N+Q +
Sbjct: 938 VGLNRELLLQEDDSGSDTKYKILEGRNESALKTTLAMKEEKIVLLEAQMEEKASLNRQLE 997
Query: 322 QHFRSMKQQYEQKITELRQKLADLQKQVTDLE-------AEREQKQ------RDFDRKLL 368
+ +K++ E LRQ + Q + A + K+ ++ +LL
Sbjct: 998 SELQMLKKECE----TLRQNQGEGQHLQNSFKHPAGKTAASHQGKEAWGPGHKEATMELL 1053
Query: 369 LAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQ---REYQEKEIQRLNKALE- 424
K + E + L AE + L++++++L+ Q + Q + Q +Q N L+
Sbjct: 1054 RVKDRAIELERNNAALQAEKQLLKEQLQHLETQNVTFSSQILTLQKQSAFLQEHNTTLQT 1113
Query: 425 EALSIQTPPSSPPTAFGSPEGAGALLRKQELV--TQNELLKQQ-------VKIFEEDFQR 475
+ +Q S+ + + LL+ T+NE L++Q + +D +
Sbjct: 1114 QTAKLQVENSTLSSQSAALTAQYTLLQNHHTAKETENESLQRQQEQLTAAYEALLQDHEH 1173
Query: 476 ERSDRERMNEEKEELKKQ---VEKLQAQVTLSNAQL----------KAFKDEEK-----A 517
+ ER + E E L +Q ++ L + L + +L KA +E +
Sbjct: 1174 LGTLHERQSAEYEALIRQHSCLKTLHRNLELEHKELGERHGDMLKRKAELEEREKVLTTE 1233
Query: 518 REALRQQKR-KAKASGE 533
REAL+Q++R A A GE
Sbjct: 1234 REALQQEQRTNALAMGE 1250
Score = 37.4 bits (85), Expect = 0.042
Identities = 80/368 (21%), Positives = 138/368 (37%), Gaps = 69/368 (18%)
Query: 40 QGIKMLGELLEESQMEATRLRQKAEELVKDNELLPPPSPSLGSFDPLAELTGKDSNVTAS 99
QG + G +E+ ME R++ +A EL ++N L L + L L + NVT S
Sbjct: 1036 QGKEAWGPGHKEATMELLRVKDRAIELERNNAALQAEKQLLK--EQLQHL--ETQNVTFS 1091
Query: 100 PTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSPESSSHANAMALGPL------PRE 153
A +Q+ T+ + + + +NS SS A A L +E
Sbjct: 1092 SQILTLQKQS-AFLQE---HNTTLQTQTAKLQVENSTLSSQSAALTAQYTLLQNHHTAKE 1147
Query: 154 DGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASK------VHKN------ 201
N L Q+ + T + A DH L T R + E+ L + +H+N
Sbjct: 1148 TENESLQRQQEQLTAAYEALLQDHEHLGTLHERQSAEYEALIRQHSCLKTLHRNLELEHK 1207
Query: 202 ----------------EQRTSILQTLCEQLRKE----------NEALKAKLDKGLEQRDQ 235
E+R +L T E L++E N+ L+ +LD+ Q
Sbjct: 1208 ELGERHGDMLKRKAELEEREKVLTTEREALQQEQRTNALAMGENQRLRGELDRVNFLHHQ 1267
Query: 236 AAERLREENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVA 295
E + K+L S N + R + + Q ++ K+
Sbjct: 1268 LKGEYEELHAHTKELKTSLNNAQLELNR-----WQARFDELKEQHQTMDISLTKLDNHCE 1322
Query: 296 LGAAEK------------KVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLA 343
L + K ++++L QQ LLE N + + + ++QY K+ LR+
Sbjct: 1323 LLSRLKGNLEEENHHLLSQIQLLSQQNQMLLEQNMENKEQYHEEQKQYIDKLNALRRHKE 1382
Query: 344 DLQKQVTD 351
L++++ D
Sbjct: 1383 KLEEKIMD 1390
Score = 35.0 bits (79), Expect = 0.21
Identities = 46/212 (21%), Positives = 83/212 (39%), Gaps = 34/212 (16%)
Query: 322 QHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDK 381
QH + ++ +RQ+L D +Q+ D E +Q L+L K++ E
Sbjct: 250 QHLAVELADTKARLRRVRQELEDKTEQLVDTRHEVDQ--------LVLELQKVKQENI-- 299
Query: 382 EQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFG 441
QL A+A+ R L D L + E E E+ R + L + +
Sbjct: 300 -QLAADARSARAYRDEL-DSLREKANRVERLELELTRCKEKLHDVDFYKA---------- 347
Query: 442 SPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNE-EKE--ELKKQVEKLQ 498
R +EL N +L + + EE R+ ++++E EKE +LK ++ L+
Sbjct: 348 ---------RMEELREDNIILIETKAMLEEQLTAARARGDKVHELEKENLQLKSKLHDLE 398
Query: 499 AQVTLSNAQLKAFKDEEKAREALRQQKRKAKA 530
+++ +E E ++Q A
Sbjct: 399 LDRDTDKKRIEELLEENMVLEIAQKQSMNESA 430
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 70.5 bits (171), Expect = 5e-12
Identities = 92/403 (22%), Positives = 171/403 (42%), Gaps = 43/403 (10%)
Query: 163 RLETTLSVCAE-EPDHGQLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEA 221
RL TL C + + + Q+ + +++ E L+ K+ + LQ +L +E+
Sbjct: 291 RLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSK 350
Query: 222 L-------KAKLDKGLEQRDQAAERLREENLELK-KLLMSNGNKEGASGRPGSPKMEGTG 273
+A+L+K L Q + L E+N L+ KL + P K E G
Sbjct: 351 ATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLG 410
Query: 274 K--KAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQY 331
+ +Q+A+ A ++ A +V+MLE +R + HF KQQ
Sbjct: 411 DVLQLETLKQEAATLAANNTQLQA------RVEMLETERGQQEAKLLAERGHFEEEKQQL 464
Query: 332 EQKITELRQKLADLQKQVTDLE-------AEREQKQRDFDRKLLLAKSKIEMEETDKEQL 384
IT+L+ +++L + +LE A + +L + I+ ++ + L
Sbjct: 465 SSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGL 524
Query: 385 TAEAKELR--------------QKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQ 430
+AKE + Q +++ +QLS +Q+E Q KE+ +A + + Q
Sbjct: 525 KQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQ 584
Query: 431 TPPSSPPTAFGSPEGAGALLR----KQELVTQNELLKQQVKIFEEDFQRERSDRERMNEE 486
++ E AL + ++E + E+L+QQ+++ E ++ + E
Sbjct: 585 LATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQRE 644
Query: 487 KEELKKQVEKLQAQV-TLSNAQLKAFKDEEKAREALRQQKRKA 528
K EL ++VE+LQA V T Q +A + LR +++KA
Sbjct: 645 KAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKA 687
Score = 70.1 bits (170), Expect = 6e-12
Identities = 113/531 (21%), Positives = 231/531 (43%), Gaps = 86/531 (16%)
Query: 20 EASAAFERLVKENSRLKEKMQGIKM-LGELLEESQ---MEATRLRQKAEELVKDNELLPP 75
E AA KE L++K + + M L E L++ Q E +++ +K +L ++N L
Sbjct: 266 EKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSF 325
Query: 76 PSPSLGSF-----DPLAELTGKDSNVTASPTAPACPSDKPAPVQKPPSSGTSSEFEVVTP 130
S D L ELT + S T +K A ++K S+ + +
Sbjct: 326 KLREFASHLQQLQDALNELTEEHSKATQEWL------EKQAQLEKELSAALQDKKCL--- 376
Query: 131 EEQNS------PESSSHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQLFTHL 184
EE+N + H + + P P+E G ++ + +LET
Sbjct: 377 EEKNEILQGKLSQLEEHLSQLQDNP-PQEKGEVLGDVLQLET------------------ 417
Query: 185 GRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREEN 244
+ E LA+ + + R +L+T + ++ L A+ E++ Q + + +
Sbjct: 418 --LKQEAATLAANNTQLQARVEMLET---ERGQQEAKLLAERGHFEEEKQQLSSLITDLQ 472
Query: 245 LELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVK 304
+ L + E AS + G + A Q AS+T+ + ++++
Sbjct: 473 SSISNLSQAKEELEQAS--------QAHGARLTA--QVASLTSELTTLNATIQQQDQELA 522
Query: 305 MLEQQRSE----LLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQ 360
L+QQ E L + +Q +Q + ++ Q EQ + L+QK ++Q+ ++ ++E +
Sbjct: 523 GLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQK----EQQLKEVAEKQEATR 578
Query: 361 RDFDRKLLLAKSKIEMEETDKE----QLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEI 416
+D ++L A + E +++ QL A KE K++ LQ QL R+ + +
Sbjct: 579 QDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSV 638
Query: 417 -QRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQR 475
Q + E + ++ + TA A A + + EL ++E Q+
Sbjct: 639 TQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSE-------------QQ 685
Query: 476 ERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKR 526
+ +++ER+ +EK++L++Q++ L+ + ++ L+ +++ +A +AL +Q+R
Sbjct: 686 KATEKERVAQEKDQLQEQLQALKESLKVTKGSLE--EEKRRAADALEEQQR 734
Score = 64.3 bits (155), Expect = 3e-10
Identities = 78/355 (21%), Positives = 149/355 (41%), Gaps = 41/355 (11%)
Query: 211 LCEQLRKENEALKAKLDKGLEQRDQAAERLREENL-------ELKKLLMSNGNKEGASGR 263
LC+QL+ E A + + + LEQ QAA LR E L EL L +E + +
Sbjct: 1366 LCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQ 1425
Query: 264 PGSPKME--------------------GTGKKAVAGQQQASVTAGKVPEV----VALGAA 299
+ K G G++A G+Q V + E +A A
Sbjct: 1426 LRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRA 1485
Query: 300 EKKVKMLEQQR-----SELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEA 354
+ + ++ E QR + LEV + + + Q+ E RQKL +Q+ +
Sbjct: 1486 DAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQR 1545
Query: 355 EREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEK 414
E+ ++ + +KL + ++++ + + A+ E +Q+ + LQ QL+ L Q +E+
Sbjct: 1546 EQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQ 1605
Query: 415 EIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQ 474
+ +E+A + + E L ++L +N+ L+ + + + Q
Sbjct: 1606 AAEHYKLQMEKAKTHYDAKKQQ-----NQELQEQLRSLEQLQKENKELRAEAERLGHELQ 1660
Query: 475 RERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAK 529
+ + + L QV L+AQV ++ QL+ + A +AL+ ++ +AK
Sbjct: 1661 QAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAK 1715
Score = 57.8 bits (138), Expect = 3e-08
Identities = 107/534 (20%), Positives = 221/534 (41%), Gaps = 63/534 (11%)
Query: 26 ERLVKENSRLKEKMQGIKMLGELLEESQMEATRLRQKAEELVKDNELLPPPSPSLGSFDP 85
+ L + KEK L + L++ + + LR + E+L + L L
Sbjct: 519 QELAGLKQQAKEKQA---QLAQTLQQQEQASQGLRHQVEQL---SSSLKQKEQQLKEVAE 572
Query: 86 LAELTGKDSN---VTASPTAPACPSDKPAPVQKPPS--SGTSSEFEVVTPEEQNSPESSS 140
E T +D TA+ A ++ A +++ + +++ E++ + Q + E+
Sbjct: 573 KQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARD 632
Query: 141 HANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKVHK 200
A ++ RE L ++ L+ + +E Q + + L+ K +
Sbjct: 633 SAQT-SVTQAQREKAELSRKVEELQACVETARQEQHEAQ--AQVAELELQLRSEQQKATE 689
Query: 201 NEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGN---- 256
E+ L EQL+ E+LK E++ +AA+ L E+ + +L +
Sbjct: 690 KERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQ 749
Query: 257 --------KEGASGRPG-SPKMEGTGKKAVAGQQQASVTAGKVPEVVALG-AAEKKVKML 306
+E +GR G +++ G+ A Q + V ++ E +A AE + + L
Sbjct: 750 HKRERKELEEERAGRKGLEARLQQLGE---AHQAETEVLRRELAEAMAAQHTAESECEQL 806
Query: 307 EQQRS---ELLEVNKQWDQHFRSMKQQY----EQKITELRQKLADLQKQVTDLEAEREQK 359
++ + E E ++Q + + +M Q+ +++ + RQ+L + +++V +E+ E
Sbjct: 807 VKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSE-- 864
Query: 360 QRDFDRKLLLAKSKIEMEETDKEQLTA--EAKELRQKVKYLQDQLSPLTRQREYQEKEIQ 417
L +++ + E+ E A + +E + + L D LS L + KE+
Sbjct: 865 -------LQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVA 917
Query: 418 RLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRER 477
RL + +A Q S P AG Q E L++Q F +
Sbjct: 918 RLETLVRKAGEQQETASRELVK--EPARAGD--------RQPEWLEEQQG---RQFCSTQ 964
Query: 478 SDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREA-LRQQKRKAKA 530
+ + M E E++ ++E+L+A + S Q + + +++ A L Q++ +A+A
Sbjct: 965 AALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQA 1018
Score = 52.4 bits (124), Expect = 1e-06
Identities = 86/368 (23%), Positives = 155/368 (42%), Gaps = 41/368 (11%)
Query: 186 RMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREENL 245
R+ L AS + +R+S L+ + LR+E E + + ++ AER E
Sbjct: 1268 RLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQ 1327
Query: 246 ELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKM 305
ELK KE A + ++E T +A+ + +P + +
Sbjct: 1328 ELKAWQEKFFQKEQAL---STLQLEHTSTQALVSE--------LLPAKHLCQQLQAEQAA 1376
Query: 306 LEQQRSELLEVNKQWDQHFRSMKQQYEQKITE---LRQKLADLQKQVTDLEAEREQ--KQ 360
E++ E LE +KQ R+ + ++++ E LRQK+A+ ++ L AE+ +Q
Sbjct: 1377 AEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQ 1436
Query: 361 RDFDRKL--LLAKSKI---EMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKE 415
+K LLA+ E ++ L E + R+ KY+Q +L+ + E + E
Sbjct: 1437 LSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQARE--KYVQ-ELAAVRADAETRLAE 1493
Query: 416 IQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELL----KQQVKIFEE 471
+QR ++ L + T E +Q+L Q E L ++Q K EE
Sbjct: 1494 VQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEE 1553
Query: 472 DFQRERSDRERMNEEKEELK----------KQVEKLQAQVTLSNAQLKAFKDEEKAREAL 521
++ + ++++LK ++ ++LQAQ+ AQL +E+A E
Sbjct: 1554 LSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQL---SQKEQAAEHY 1610
Query: 522 RQQKRKAK 529
+ Q KAK
Sbjct: 1611 KLQMEKAK 1618
Score = 51.2 bits (121), Expect = 3e-06
Identities = 105/471 (22%), Positives = 191/471 (40%), Gaps = 67/471 (14%)
Query: 99 SPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSPESSSHANAMALGPLPREDGNLM 158
+P C S P + PPS E + E SSS N G G+++
Sbjct: 154 APVPSTCSSTFPEELS-PPSHQAKREIRFL---ELQKVASSSSGNNFLSGSPASPMGDIL 209
Query: 159 ----LHLQRLETTLS--------VCAEEPDHGQLFTH----LGRMALEFNRLASKVHKNE 202
++RL+ L+ + E ++ +L T + M +RLA +++ +
Sbjct: 210 QTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLAL-LNEKQ 268
Query: 203 QRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGN-----K 257
+ + E+LR +NE+L +L + L+Q + + ++ +L NG+ +
Sbjct: 269 AASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLR 328
Query: 258 EGAS--GRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLE 315
E AS + E T + + A Q+ A E L AA + K LE++ L
Sbjct: 329 EFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKE---LSAALQDKKCLEEKNEILQG 385
Query: 316 VNKQWDQHFRSMKQQYEQKITELR---QKLADLQKQVTDLEAEREQKQRDFDRKLLLAKS 372
Q ++H ++ Q+ E+ +L L+++ L A Q Q +
Sbjct: 386 KLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQ-----------A 434
Query: 373 KIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTP 432
++EM ET++ Q A+ R + + QLS L + + + + LE+A
Sbjct: 435 RVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQA------ 488
Query: 433 PSSPPTAFGSPEGAGALLRKQELVTQNELLKQQ------VKIFEEDFQRERSDRERMNEE 486
A G+ A EL T N ++QQ +K ++ Q + + + E+
Sbjct: 489 ----SQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQ 544
Query: 487 KEE-LKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQ--KRKAKASGER 534
+ L+ QVE+L + + QLK +++ EA RQ ++ A A+ ER
Sbjct: 545 ASQGLRHQVEQLSSSLKQKEQQLKEVAEKQ---EATRQDHAQQLATAAEER 592
Score = 48.9 bits (115), Expect = 1e-05
Identities = 75/335 (22%), Positives = 135/335 (40%), Gaps = 40/335 (11%)
Query: 213 EQLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKEG--ASGRPGSPKME 270
EQ+ E E L+A L +E + Q E ++ E+ +L G + A + ++E
Sbjct: 975 EQMGNELERLRAAL---MESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELE 1031
Query: 271 GTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQ 330
+ A+ Q+ T + E +A EK+ K +Q+ ++L R ++
Sbjct: 1032 MRLQNALNEQRVEFAT---LQEALAHALTEKEGK--DQELAKL-----------RGLEAA 1075
Query: 331 YEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKE 390
+++ ELRQ + L++Q+ A++E++ A + E E L AE +
Sbjct: 1076 QIKELEELRQTVKQLKEQL----AKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSK 1131
Query: 391 LRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALL 450
L Q+ + Q+Q L R E + + ALE ++Q G + A A
Sbjct: 1132 LEQQCQKQQEQADSLERSLEAERASRAERDSALE---TLQGQLEEKAQELGHSQSALASA 1188
Query: 451 RKQELVTQNELLKQQVKIFEE---DFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQ 507
++ EL ++ K +E R R + ER N L+++V L QV +
Sbjct: 1189 QR-ELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGE 1247
Query: 508 LKAFK--------DEEKAREALRQQKRKAKASGER 534
K K +K E LR + + ++ R
Sbjct: 1248 SKELKRLVMAESEKSQKLEERLRLLQAETASNSAR 1282
Score = 47.8 bits (112), Expect = 3e-05
Identities = 112/527 (21%), Positives = 198/527 (37%), Gaps = 56/527 (10%)
Query: 35 LKEKMQGIKMLGELLEESQMEATRLRQKAEELVKDNELLPPPSPSLGSFDPLAELTGKDS 94
L+E Q +K L E L + + E E E P P L + L K
Sbjct: 1080 LEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTE---PTGPKL---EALRAEVSKLE 1133
Query: 95 NVTASPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSPESSSHANAMALGPLPRED 154
A ++ ++ + S E + + + + H+ + AL RE
Sbjct: 1134 QQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQS-ALASAQRE- 1191
Query: 155 GNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQ 214
L T + ++ D + GR E R S + E+ SIL +
Sbjct: 1192 ------LAAFRTKVQDHSKAEDEWKAQVARGRQEAE--RKNSLISSLEEEVSILNRQVLE 1243
Query: 215 LRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRPGSPKMEGTGK 274
E++ LK + E+ + ERLR E + A E K
Sbjct: 1244 KEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEK 1303
Query: 275 KAVAGQ---QQASVTAGKVPEV-VALGAAEKKVKMLEQQRSEL-LE-------VNKQWDQ 322
+ VA + Q+ + A + E+ L A ++K EQ S L LE V++
Sbjct: 1304 QRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPA 1363
Query: 323 HFRSMKQQYEQKITEL--RQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETD 380
+ Q EQ E R++L ++ L AE + QR+ +L+ + K+ +E
Sbjct: 1364 KHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELG-ELIPLRQKVAEQERT 1422
Query: 381 KEQLTAEAKELRQKVKYLQDQLSPLTRQ-----------REYQEKEIQRLNKALEEALSI 429
+QL AE +++ L+ L + R++ E E+ + + + L+
Sbjct: 1423 AQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAA 1482
Query: 430 QTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEE 489
+ A E A + R+ E++T + +VK+ EE R+R EE+++
Sbjct: 1483 VRADAETRLAEVQRE-AQSTARELEVMTA-KYEGAKVKVLEE--------RQRFQEERQK 1532
Query: 490 LKKQVEKLQAQVTLSNAQL----KAFKDEEKAREALRQQKRKAKASG 532
L QVE+L+ Q+ K D ++A + +Q+ + +A G
Sbjct: 1533 LTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQG 1579
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 70.1 bits (170), Expect = 6e-12
Identities = 99/464 (21%), Positives = 197/464 (42%), Gaps = 70/464 (15%)
Query: 93 DSNVTASPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSPESSSHANAMALGPLPR 152
D + +P+ SD +K ++GT+ E T +SPE A+ L R
Sbjct: 57 DHHPQTNPSVGTAASDTK---KKKINNGTNPE--TTTSGGCHSPEDEQKASHQHQEALRR 111
Query: 153 EDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMAL-----EFNRLASKVHKN------ 201
E L+ T+ + + Q+ + + A+ E L S++H +
Sbjct: 112 E-------LEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGE 164
Query: 202 -EQRTSILQT-------LCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELK-KLLM 252
EQ S + T E+L KE +AL +L + E L+E+N +L+ KL +
Sbjct: 165 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTI----TDEELKEKNAKLQEKLQL 220
Query: 253 SNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSE 312
K K + K + QQQ A + K+++ + +
Sbjct: 221 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG---------KELQSVSAKLQA 271
Query: 313 LLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKS 372
+E N+ W++ + QQ E+K+ +K+ + ++++ E+E+K R+ + K+ +
Sbjct: 272 QVEENELWNR----LNQQQEEKMWRQEEKIQEREEKIQ----EQEEKIREQEEKMRRQEE 323
Query: 373 KIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTP 432
+ +E + E +K++ L++++ + RE +EK + EE + Q
Sbjct: 324 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE------EEKIREQEK 377
Query: 433 PSSPPTAFGSPEGAGALLRKQELVT-QNELLKQQVKIFEEDFQRERSDRERMNEEKEELK 491
E + R++E + Q E +++Q ++ +E ++ E+M E++EE++
Sbjct: 378 RQ---------EQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ 428
Query: 492 KQVEKLQAQVTLSNAQLKAFKD-EEKAREALRQQKRKAKASGER 534
+Q EK++ Q Q K ++ EEK RE + + + GE+
Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ 472
Score = 66.6 bits (161), Expect = 7e-11
Identities = 72/354 (20%), Positives = 166/354 (46%), Gaps = 53/354 (14%)
Query: 183 HLGRMALEFN-RLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLR 241
HLG+ + +L ++V +NE + Q E++ ++ E ++ + +K EQ E++R
Sbjct: 257 HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQE----EKIR 312
Query: 242 EENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEK 301
E+ ++++ KE R E K+ E+ ++
Sbjct: 313 EQEEKMRRQEEMMWEKEEKMRRQEEMMWE---------------KEEKIRELEEKMHEQE 357
Query: 302 KVKMLEQQRSE---LLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQ 358
K++ E++R E + E K+ +Q + +Q E+KI E +K+ + ++ + E+E+
Sbjct: 358 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQ--EEKIREQEEKIREQEEMMQ----EQEE 411
Query: 359 KQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQR 418
K + + K+ + +++ +E E++ + +++R++ K +++Q + Q E +++ ++
Sbjct: 412 KMGEQEEKMWEQEEEMQEQE---EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 468
Query: 419 LNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQE--LVTQNELLKQQVKIFEEDFQRE 476
+ + + + E +R+QE + Q E +++Q ++ +E ++
Sbjct: 469 MGEQEGKMCEQEAKMQEQEEKMRRQEEK---IREQEKKIREQEEKIREQEEMMQEQEEKM 525
Query: 477 RSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKARE---ALRQQKRK 527
E+M E++E++++Q EK++ Q EEK RE LRQQ+ K
Sbjct: 526 WEQEEKMCEQEEKMQEQEEKMRRQ-------------EEKMREQEVRLRQQEEK 566
Score = 39.3 bits (90), Expect = 0.011
Identities = 44/225 (19%), Positives = 110/225 (48%), Gaps = 21/225 (9%)
Query: 197 KVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGN 256
K+ + E++ + + EQ +++ + +AK+ + E+ + E++RE+ +++ G
Sbjct: 358 KIREQEEKRQEEEKIREQEKRQEQ--EAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGE 415
Query: 257 KEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVK----MLEQQRSE 312
+E +M+ +K +++ K+ E E+K++ M+++Q +
Sbjct: 416 QEEKMWEQ-EEEMQEQEEKMRRQEEKIREQEKKIRE------QEEKIREQEEMMQEQEEK 468
Query: 313 LLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEA---EREQKQRDFDRKLLL 369
+ E + + M++Q E+K+ +K+ + +K++ + E E+E+ ++ + K+
Sbjct: 469 MGEQEGKMCEQEAKMQEQ-EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 527
Query: 370 AKSKI-EMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQE 413
+ K+ E EE +EQ E K RQ+ K + ++ ++ + QE
Sbjct: 528 QEEKMCEQEEKMQEQ---EEKMRRQEEKMREQEVRLRQQEEKMQE 569
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 70.1 bits (170), Expect = 6e-12
Identities = 77/362 (21%), Positives = 168/362 (46%), Gaps = 31/362 (8%)
Query: 194 LASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGL-----EQRDQAAERLREENLELK 248
L K+ E S +Q ++L+++ E K L + E+ + E LRE+ +++
Sbjct: 192 LQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIR 251
Query: 249 KLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQ 308
K +E R KM +K +++ ++ E +KK++ E+
Sbjct: 252 KQEEKMWRQEERL-REQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEE 310
Query: 309 QRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAE-REQKQRDFDRKL 367
Q E E K W+Q + +Q E+K+ ++L + +KQ+ + E + R+Q++R +++
Sbjct: 311 QMQEQEE--KMWEQEEKMREQ--EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 366
Query: 368 LLAKSKIEMEETDK----EQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKAL 423
L + + M E +K E+ E + +R++ K ++++ + Q E +K+ + + +
Sbjct: 367 RLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 426
Query: 424 EEALSIQTPPSSPPTAFGSP---EGAGALLRKQELVT-QNELLKQQVKIFEEDFQRERSD 479
E+ Q P + E + ++E + Q E+ Q+ K++ ++ RE+ D
Sbjct: 427 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 486
Query: 480 R------------ERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRK 527
+ ++M +++E + +Q E+L+ + Q K ++ EEK RE + Q+++
Sbjct: 487 QMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQE 546
Query: 528 AK 529
K
Sbjct: 547 KK 548
Score = 65.1 bits (157), Expect = 2e-10
Identities = 68/353 (19%), Positives = 161/353 (45%), Gaps = 31/353 (8%)
Query: 197 KVHKNEQRTSILQTLCEQLRK--ENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSN 254
++ + E+R + + EQ K E E ++ + +K + + ++ E+ + ++ +
Sbjct: 367 RLREKEERMREQEKMWEQEEKMQEEERIRER-EKKMREEEETMREQEEKMQKQEENMWEQ 425
Query: 255 GNKEGASGR-PGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKV---------- 303
KE R P + +K +++ K+ + + EKK+
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 485
Query: 304 -KMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQ-R 361
+M EQ+ + K WDQ R +Q ++++ E +++ + +K E RE+K+ +
Sbjct: 486 DQMWEQEEKMRDQEQKMWDQEERMWEQ--DERLREKEERMREQKKMWQQEEKMREEKKTQ 543
Query: 362 DFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNK 421
+ ++K + K+ EE +E+ K++R++ + +++Q + +E +EK ++ K
Sbjct: 544 EQEKKTWDQEEKMREEERMRER----EKKMREEEEMMREQEE---KMQEQEEKMREQEEK 596
Query: 422 ALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRE 481
E+ +Q + E + ++ Q E++ +Q + +E ++ E
Sbjct: 597 MWEQEEKMQEQEEK---MWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEE 653
Query: 482 RMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGER 534
+M E++E++++Q EK+Q Q Q + + +E E +R+Q+ K + E+
Sbjct: 654 KMREQEEKMREQEEKMQGQEEKMREQEEKMQGQE---EKMREQEEKMRGQEEK 703
Score = 64.7 bits (156), Expect = 2e-10
Identities = 84/386 (21%), Positives = 165/386 (42%), Gaps = 59/386 (15%)
Query: 153 EDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKV---HKNEQRTSILQ 209
EDGNL E D H A E R S V HK R
Sbjct: 119 EDGNL--------------GESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADR----- 159
Query: 210 TLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELK-KLLMSNGNKEGASGRPGSPK 268
E+L KE +AL +L + E L+++N EL+ KL ++ K K
Sbjct: 160 -YIEELTKERDALSLELYRNTITN----EELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
Query: 269 MEGTGKKAVAGQQQASVTAGKV-PEVVALGAAEKKVKMLEQ----QRSELLEVNKQWDQH 323
+ K + Q Q + ++ + L EKK++ E+ Q L E + +
Sbjct: 215 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 274
Query: 324 FRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQ 383
M++Q E+++ E ++L + +K++ + + REQ+++ +++ + + + +M E + E+
Sbjct: 275 EEKMRRQ-EKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE-EK 332
Query: 384 LTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSP 443
+ + + L ++ K +++Q + Q E ++ +RL + E
Sbjct: 333 MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEER------------------ 374
Query: 444 EGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTL 503
+R+QE + + E Q+ + E ++ R + E M E++E+++KQ E + Q
Sbjct: 375 ------MREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 428
Query: 504 SNAQLKAFKDEEKAREALRQQKRKAK 529
Q + + +EK E + Q+++ K
Sbjct: 429 EWQQQRLPEQKEKLWEQEKMQEQEEK 454
Score = 62.0 bits (149), Expect = 2e-09
Identities = 63/247 (25%), Positives = 111/247 (44%), Gaps = 40/247 (16%)
Query: 331 YEQKIT--ELRQKLADLQKQVTDLEAEREQKQ---RDFDRKLLLAKSKIEMEETD--KEQ 383
Y IT EL++K A+LQ+++ E+E+ + Q ++ RKL AK + +T+ +E+
Sbjct: 176 YRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEE 235
Query: 384 LTAEAKELRQKVKYLQDQLSPLTRQREY------------------------QEKEIQRL 419
+ + +ELR++ K ++ Q + RQ E QEKE++
Sbjct: 236 MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQ 295
Query: 420 NKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQE--LVTQNELLKQQVKIFEEDFQRER 477
K L E ++ +R+QE + Q E L +Q K E Q+ R
Sbjct: 296 EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 355
Query: 478 SDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGERYHV 537
ERM E+ E L+++ E+++ Q K ++ EEK +E R ++R+ K E +
Sbjct: 356 DQEERMWEQDERLREKEERMREQE-------KMWEQEEKMQEEERIREREKKMREEEETM 408
Query: 538 EPHPEHL 544
E +
Sbjct: 409 REQEEKM 415
Score = 58.5 bits (140), Expect = 2e-08
Identities = 68/324 (20%), Positives = 149/324 (45%), Gaps = 44/324 (13%)
Query: 213 EQLRKENEALKAKLDKGLEQRD--QAAERLREENLELKKLLMSNGNKEGASGRPGSPKME 270
E+LR++ E ++ + +K EQ + Q ER+RE ++++ E + R KM+
Sbjct: 366 ERLREKEERMREQ-EKMWEQEEKMQEEERIREREKKMRE--------EEETMREQEEKMQ 416
Query: 271 GTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQ 330
+Q+ ++ + E E+K K+ EQ++ + E K W+Q ++ Q
Sbjct: 417 ---------KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQE-EKIWEQE-EKIRDQ 465
Query: 331 YEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKE 390
E E + + ++ D E+E+K RD ++K+ + + M E D+ E +
Sbjct: 466 EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER--MWEQDERLREKEERM 523
Query: 391 LRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALL 450
QK + Q++ ++ + QEK+ + + E ++
Sbjct: 524 REQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRE------------------- 564
Query: 451 RKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKA 510
R++++ + E++++Q + +E ++ R E+M E++E++++Q EK+ Q Q +
Sbjct: 565 REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE 624
Query: 511 FKDEEKAREALRQQKRKAKASGER 534
K +E+ E + +Q+ K + E+
Sbjct: 625 DKMQEQ-EEMMWEQEEKMQEQEEK 647
Score = 58.5 bits (140), Expect = 2e-08
Identities = 53/244 (21%), Positives = 117/244 (47%), Gaps = 20/244 (8%)
Query: 306 LEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDR 365
L ++ + E K W Q K + E+K E +K D ++++ + E RE++++ +
Sbjct: 516 LREKEERMREQKKMWQQE---EKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 572
Query: 366 KLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQRE--YQEKEIQRLNKAL 423
+ ++ + + +M+E +++ E K Q+ K +Q+Q + Q E ++++E ++ +
Sbjct: 573 EEMMREQEEKMQEQEEKMREQEEKMWEQEEK-MQEQEEKMWEQEEKMWEQEEEDKMQEQE 631
Query: 424 EEALSIQTPPSSPPTAFGSPEGAGALLRKQE--LVTQNELLKQQVKIFEEDFQRERSDRE 481
E + E +R+QE + Q E ++ Q + E ++ + E
Sbjct: 632 EMMWEQEEKMQEQEEKMWEQEEK---MREQEEKMREQEEKMQGQEEKMREQEEKMQGQEE 688
Query: 482 RMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEK--AREALRQQKRKAKASGERYHVEP 539
+M E++E+++ Q EK+ Q + K + EEK +E +R+++ + + E+ E
Sbjct: 689 KMREQEEKMRGQEEKMWGQ------EEKMWGQEEKMWGQEEMREKEERIRDQKEKMQ-ER 741
Query: 540 HPEH 543
PEH
Sbjct: 742 LPEH 745
Score = 46.2 bits (108), Expect = 9e-05
Identities = 44/207 (21%), Positives = 97/207 (46%), Gaps = 13/207 (6%)
Query: 213 EQLRKENEALKAKLDKGLEQRD--QAAERLREENL----ELKKLLMSNGNKEGASGRPGS 266
E++ +++E L+ K ++ EQ+ Q E++REE E K +E R
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566
Query: 267 PKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRS 326
KM + +++ K+ E E++ KM EQ+ + K W+Q
Sbjct: 567 KKMREEEEMMREQEEKMQEQEEKMREQEEK-MWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
Query: 327 MKQQYEQKITELRQKLADLQKQVTDLE---AEREQKQRDFDRKLLLAKSKIEMEETDKEQ 383
Q+ E+ + E +K+ + ++++ + E E+E+K R+ + K+ + K+ +E E+
Sbjct: 626 KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE---EK 682
Query: 384 LTAEAKELRQKVKYLQDQLSPLTRQRE 410
+ + +++R++ + ++ Q + Q E
Sbjct: 683 MQGQEEKMREQEEKMRGQEEKMWGQEE 709
Score = 41.6 bits (96), Expect = 0.002
Identities = 58/281 (20%), Positives = 128/281 (45%), Gaps = 34/281 (12%)
Query: 186 RMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKA-KLDKGLEQRDQAAERLREEN 244
RM + RL K + ++ + Q E++R+E + + K E++ + ER+RE
Sbjct: 508 RMWEQDERLREKEERMREQKKMWQQE-EKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566
Query: 245 LELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVK 304
++++ E R KM+ +K +++ K+ E E++ K
Sbjct: 567 KKMRE--------EEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK-MWEQEEK 617
Query: 305 MLEQQRSELLEVNKQ--WDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAE---REQK 359
M EQ+ + ++ ++ W+Q Q+ E+K+ E +K+ + ++++ + E + +E+K
Sbjct: 618 MWEQEEEDKMQEQEEMMWEQ--EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 675
Query: 360 QRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKE---- 415
R+ + K+ + K+ +E E++ + +++ + + + Q + Q E +EKE
Sbjct: 676 MREQEEKMQGQEEKMREQE---EKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIR 732
Query: 416 --IQRLNKALEEALSIQTPPSSPPTAF-------GSPEGAG 447
+++ + L E + P PP+ GS E AG
Sbjct: 733 DQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAG 773
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 69.7 bits (169), Expect = 8e-12
Identities = 74/353 (20%), Positives = 167/353 (47%), Gaps = 36/353 (10%)
Query: 183 HLGRMALEFN-RLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRD---QAAE 238
HLG+ + +L ++V +NE + Q E++ ++ E ++ +K EQ + + E
Sbjct: 269 HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328
Query: 239 RLREENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGA 298
++RE+ ++++ KE R E K ++ E+ +
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR------------RLEEM--MWE 374
Query: 299 AEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQ 358
E+K++ LE++ E ++ +Q ++ K + ++K E K+ ++++ E+E+
Sbjct: 375 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR----EQEE 430
Query: 359 KQRDFDRKLLLAKSKI-EMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQ 417
K R+ ++K+ + KI E E+ +E+ E +E+ ++ + +++Q + RQ+E ++ +
Sbjct: 431 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ-EEIWRQKEKMHEQ-E 488
Query: 418 RLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRER 477
++ K E+ + E +++ Q E +++Q + E ++ R
Sbjct: 489 KIRKQEEKVWRQEEKMHDQEEKIREQE--------EKMWRQEEKIREQEEKIREQEEKIR 540
Query: 478 SDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAR---EALRQQKRK 527
E M E++E++ +Q EK+Q Q + + K + EEK R E +R+Q+ K
Sbjct: 541 EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEK 593
Score = 65.5 bits (158), Expect = 1e-10
Identities = 101/472 (21%), Positives = 204/472 (43%), Gaps = 63/472 (13%)
Query: 93 DSNVTASPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSPESSSHANAMALGPLPR 152
D + +P+ SD +K ++GT+ E T +SPE A+ L R
Sbjct: 69 DHHPQTNPSVGTAASDTK---KKKINNGTNPE--TTTSGGCHSPEDEQKASHQHQEALRR 123
Query: 153 EDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMAL-----EFNRLASKVHKN------ 201
E L+ T+ + + Q+ + + A+ E L S++H +
Sbjct: 124 E-------LEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGE 176
Query: 202 -EQRTSILQT-------LCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELK-KLLM 252
EQ S + T E+L KE +AL +L + E L+E+N +L+ KL +
Sbjct: 177 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTI----TDEELKEKNAKLQEKLQL 232
Query: 253 SNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQ--- 309
K K + K + QQQ A + + + +A+ + ++ E +
Sbjct: 233 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWN 292
Query: 310 RSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAE-REQKQRDFDRKLL 368
R + K W Q + Q++E+KI E +K+ + ++++ + E + R Q++ ++++
Sbjct: 293 RLNQQQEEKMWRQEEKI--QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 350
Query: 369 LAKSKIEMEETDKEQLTAEAK--ELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEA 426
+ + + M E +++ E E +K++ L++++ + RE +EK + EE
Sbjct: 351 MRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE------EEK 404
Query: 427 LSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNE--LLKQQVKIFEEDFQRERSDRERMN 484
+ Q E + ++E + + E + +Q+ KI E++ RE R+
Sbjct: 405 IREQEKRQEQEAKMWRQEEK--IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQ--- 459
Query: 485 EEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGERYH 536
E+EE+ +Q EK++ Q ++ K++ +E +R+Q+ K E+ H
Sbjct: 460 -EQEEMWRQEEKIREQ-----EEIWRQKEKMHEQEKIRKQEEKVWRQEEKMH 505
Score = 55.8 bits (133), Expect = 1e-07
Identities = 63/333 (18%), Positives = 155/333 (46%), Gaps = 18/333 (5%)
Query: 190 EFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELKK 249
+ R + + E++ L+ + + ++ L+ K+ + + R+Q +R EE + ++
Sbjct: 350 KMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 409
Query: 250 LLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQ 309
++ A K+ +K +++ K+ E + EK+ + E
Sbjct: 410 ----KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 465
Query: 310 RSELLEVNKQWDQHFRSMKQQYEQ-KITELRQKLADLQKQVTDLEAEREQKQRDFDRKLL 368
R E E ++ ++ +R ++ +EQ KI + +K+ ++++ D +E+K R+ + K+
Sbjct: 466 RQE--EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD----QEEKIREQEEKMW 519
Query: 369 LAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQRE-YQEKEIQRLNKALEEAL 427
+ KI +E E++ + +++R++ + +Q+Q + Q E QE+E R EE +
Sbjct: 520 RQEEKIREQE---EKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ---EEKI 573
Query: 428 SIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEK 487
Q + +++++ Q E++++Q + E ++ E+M E++
Sbjct: 574 REQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 633
Query: 488 EELKKQVEKLQAQVTLSNAQLKAFKDEEKAREA 520
E++++Q EK+ Q Q + ++ ++ EA
Sbjct: 634 EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 666
>gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]
Length = 1217
Score = 69.7 bits (169), Expect = 8e-12
Identities = 61/244 (25%), Positives = 113/244 (46%), Gaps = 30/244 (12%)
Query: 300 EKKVKMLEQQRSELLEVNKQWDQHFRSMKQQ-YEQKITELRQKLADLQ----------KQ 348
E+++ LE+++ EL + K WD+ R+++ Y Q++ E R KL +L +Q
Sbjct: 197 EERLHTLEEEKEELAQYQK-WDKMRRALEYTIYNQELNETRAKLDELSAKRETSGEKSRQ 255
Query: 349 VTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKE-------LRQKVKYLQDQ 401
+ D + + K D +R++ K+KI + +KEQL+AE +E L K K LQD+
Sbjct: 256 LRDAQQDARDKMEDIERQVRELKTKISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDE 315
Query: 402 LSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNEL 461
L+ + QR+ KE Q+L + +EE + E G Q + +L
Sbjct: 316 LAGNSEQRKRLLKERQKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQATQERTDL 375
Query: 462 LKQQVKIFEEDFQRERSDRERMNEEKEE-LKKQVEKLQAQVTLSNAQLKAFKDEEKAREA 520
+Q R + EE+++ +KK+++ L + Q+ A + + EA
Sbjct: 376 YAKQ----------GRGSQFTSKEERDKWIKKELKSLDQAINDKKRQIAAIHKDLEDTEA 425
Query: 521 LRQQ 524
+++
Sbjct: 426 NKEK 429
Score = 39.7 bits (91), Expect = 0.009
Identities = 69/348 (19%), Positives = 130/348 (37%), Gaps = 28/348 (8%)
Query: 163 RLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEAL 222
RLE V E + G+L L L + + L +Q+ +
Sbjct: 675 RLELQKDVRKAEEELGELEAKLNE------NLRRNIERINNEIDQLMNQMQQIETQQRKF 728
Query: 223 KAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQ 282
KA D L + + L+E+ + +K M + S ME T + A
Sbjct: 729 KASRDSILSEM----KMLKEKRQQSEKTFMPK-QRSLQSLEASLHAMESTRESLKAELGT 783
Query: 283 ASVTAGKVPEVVALGAAEKKVKMLEQQRSELLE-----------VNKQWDQHFRSMKQQY 331
++ + + + A +++ L+Q+ +LL V +++ R Q
Sbjct: 784 DLLSQLSLEDQKRVDALNDEIRQLQQENRQLLNERIKLEGIITRVETYLNENLRKRLDQV 843
Query: 332 EQKITELRQKLADLQKQVTDLEAEREQKQ-RDFDRKLLLAKSKIEMEETDKEQLTAEAKE 390
EQ++ ELR+ T E E K+ +D + + I+ E ++L +
Sbjct: 844 EQELNELRETEGGTVLTATTSELEAINKRVKDTMARSEDLDNSIDKTEAGIKELQKSMER 903
Query: 391 LRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEAL-SIQTPPSSPPTAFGSPEGAGAL 449
+ K D ++ T++ E L K EE + I+ S P AF +
Sbjct: 904 WKNMEKEHMDAINHDTKELEKMTNRQGMLLKKKEECMKKIRELGSLPQEAFEKYQ----T 959
Query: 450 LRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKL 497
L ++L + E ++K + ++ +E+KE+L K+ E+L
Sbjct: 960 LSLKQLFRKLEQCNTELKKYSHVNKKALDQFVNFSEQKEKLIKRQEEL 1007
Score = 33.5 bits (75), Expect = 0.61
Identities = 31/162 (19%), Positives = 76/162 (46%), Gaps = 38/162 (23%)
Query: 376 MEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREY--QEKEIQRLNKALEEALSIQTPP 433
M+ET+ ++ +++ + +KY++++L L ++E Q ++ ++ +ALE + Q
Sbjct: 179 MKETEGKR-----EKINELLKYIEERLHTLEEEKEELAQYQKWDKMRRALEYTIYNQ--- 230
Query: 434 SSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRE--RMNEEKEELK 491
EL + + K+ E +RE S + ++ + +++ +
Sbjct: 231 --------------------------ELNETRAKLDELSAKRETSGEKSRQLRDAQQDAR 264
Query: 492 KQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGE 533
++E ++ QV ++ A K+E++ A RQ++ K + E
Sbjct: 265 DKMEDIERQVRELKTKISAMKEEKEQLSAERQEQIKQRTKLE 306
Score = 31.6 bits (70), Expect = 2.3
Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 451 RKQELVTQNELLKQQVKIFEEDFQRERSDR---ERMNEEKEELKKQVEKLQAQVTLSNAQ 507
RK L Q ++ K + ++ E + + + R ER+N E ++L Q+++++ Q A
Sbjct: 672 RKSRLELQKDVRKAEEELGELEAKLNENLRRNIERINNEIDQLMNQMQQIETQQRKFKAS 731
Query: 508 LKAFKDEEKAREALRQQKRK 527
+ E K + RQQ K
Sbjct: 732 RDSILSEMKMLKEKRQQSEK 751
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 69.7 bits (169), Expect = 8e-12
Identities = 92/410 (22%), Positives = 177/410 (43%), Gaps = 54/410 (13%)
Query: 156 NLMLHLQRLETTLSVCAEEPDHGQLFTHLG--RMALEFNRLASKVHKNE------QRTSI 207
N+ LHL+RL E +H + L R L F AS ++ +RT
Sbjct: 192 NMALHLKRL------IDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTES 245
Query: 208 LQTLCEQL---RKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGN--KEGASG 262
Q L +L + + L+ +L++ EQ + L + +ELK+L N N + S
Sbjct: 246 RQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSA 305
Query: 263 RPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQ 322
R +++ +KAV + S + + + + +V+ L++ LLE +
Sbjct: 306 RMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLED 365
Query: 323 HFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKL-----LLAKSKIEME 377
+ + K+ EL ++ L+ ++ D+E ER+ ++ + + L K M+
Sbjct: 366 QLEGTRAR-SDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 424
Query: 378 ET-----DKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQ-EKEIQRLNKALEEALSIQT 431
E+ + EQ++ ++ K L +++ LT R + E E Q L K +EE
Sbjct: 425 ESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEEL----- 479
Query: 432 PPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRER-------MN 484
T S EG + + K E +N+ L ++V+I E + +E+ + +
Sbjct: 480 -----RTTVDSVEGNASKILKME--KENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLM 532
Query: 485 EEKEELKKQVEKLQAQVTLSNAQLKAFKDE-EKAREALRQQKRKAKASGE 533
+EK +L+K +E L+ S Q+K + E E + + +++++ S E
Sbjct: 533 KEKAQLEKTIETLREN---SERQIKILEQENEHLNQTVSSLRQRSQISAE 579
Score = 69.7 bits (169), Expect = 8e-12
Identities = 120/521 (23%), Positives = 213/521 (40%), Gaps = 68/521 (13%)
Query: 22 SAAFERLVKENSRLKEKMQGIKMLGELLEESQMEATRLRQKAEELVKDNELLPPPSPSLG 81
S L KEN +LK K L + +ME R+K EEL+++N L
Sbjct: 374 SDKLHELEKENLQLKAK----------LHDMEMERDMDRKKIEELMEENMTLEMAQKQ-- 421
Query: 82 SFDPLAELTGKDSNVTASPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSPESSSH 141
S D L + ++ + + + + P E +T
Sbjct: 422 SMDESLHLGWELEQIS-----------RTSELSEAPQKSLGHEVNELT------------ 458
Query: 142 ANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKVH-- 199
+ L L E+ +L ++ L TT V + E + ++ +M E RL+ KV
Sbjct: 459 --SSRLLKLEMENQSLTKTVEELRTT--VDSVEGNASKIL----KMEKENQRLSKKVEIL 510
Query: 200 KNE--QRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAER----LREENLELKKLLMS 253
+NE Q LQ C+ L K+ KA+L+K +E + +ER L +EN L + + S
Sbjct: 511 ENEIVQEKQSLQN-CQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSS 569
Query: 254 NGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSEL 313
+ S +E K + T+ K+ ++ KK +++ E
Sbjct: 570 LRQRSQISAEARVKDIEKENKIL---HESIKETSSKLSKIEFEKRQIKKELEHYKEKGER 626
Query: 314 LEVNKQWDQHFRSMKQQYEQKITELR---QKLADLQKQVTDLEAEREQKQRDFDRKLLLA 370
E + H + ++KIT L+ +K+ L+++ ++LE E + ++ D L
Sbjct: 627 AEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLT 686
Query: 371 KSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQ 430
++E E + QL E ELR+ V+ L+ S Q + + KE++ + L++ L +
Sbjct: 687 -FQLESLEKENSQLDEENLELRRNVESLK-CASMKMAQLQLENKELESEKEQLKKGLEL- 743
Query: 431 TPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEEL 490
S T G + Q L E ++++ E + Q + + + + EEL
Sbjct: 744 LKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEEL 803
Query: 491 K------KQVEKLQAQVTLSNAQLKAFKDE-EKAREALRQQ 524
K +Q+EK + +QL+ K + EK + LRQQ
Sbjct: 804 KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Score = 68.6 bits (166), Expect = 2e-11
Identities = 96/411 (23%), Positives = 178/411 (43%), Gaps = 65/411 (15%)
Query: 156 NLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQL 215
NL L+ LE S EE L R + K+ + + L++ EQL
Sbjct: 684 NLTFQLESLEKENSQLDEEN------LELRRNVESLKCASMKMAQLQLENKELESEKEQL 737
Query: 216 RKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRPGSPKMEGTGKK 275
+K E LKA K E+ + + + L EN L+K L N NK+ +E +
Sbjct: 738 KKGLELLKASFKK-TERLEVSYQGLDIENQRLQKTL-ENSNKKIQQLESELQDLEMENQT 795
Query: 276 AVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKI 335
++ +++ ++ ++ EK+ K LEQ+ S+L + KQ ++ + ++QQ E K
Sbjct: 796 LQKNLEELKISSKRLEQL------EKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKD 849
Query: 336 TELRQ---KLADLQKQ-----------------VTDLEAEREQ--KQRDFDRKLLLA--- 370
T L + K+ +L+K+ + +LE E ++ K+ D K L+
Sbjct: 850 TTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLRE 909
Query: 371 -----KSKIEMEETDKEQLTAEAKEL-RQKVKYLQDQLSPLTRQREYQEKEIQRLNKALE 424
K K + D E+LT E +++ K + L D+ S T Y+ E +L L+
Sbjct: 910 DLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQS--TDDSRYKLLE-SKLESTLK 966
Query: 425 EALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQ--RERSDRER 482
++L I+ + A R +E N+ L+Q++K +++++ ++R D ER
Sbjct: 967 KSLEIK-----------EEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEER 1015
Query: 483 MNEEKEELKKQVEKLQAQVTLSNAQLKAFKDE----EKAREALRQQKRKAK 529
M + + + K + + + +L KD E+ L+ +K+ K
Sbjct: 1016 MVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALK 1066
Score = 66.2 bits (160), Expect = 9e-11
Identities = 126/550 (22%), Positives = 229/550 (41%), Gaps = 92/550 (16%)
Query: 20 EASAAFERLVKENSRLKEKMQGIKMLGELLEE----------------SQMEATRLRQ-K 62
E + ++L E SR KE++ I+ +EE Q+E TR R K
Sbjct: 317 EKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDK 376
Query: 63 AEELVKDNELLPPPSPSLGSFDPLAELTGKDSNVTASPTAPACPSDKPAPVQKPPSSGTS 122
EL K+N L L + ++ K + K + + + G
Sbjct: 377 LHELEKENLQL---KAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQS-MDESLHLGWE 432
Query: 123 SEFEVVTPEEQNSPESS-----SHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDH 177
E T E +P+ S + + L L E+ +L ++ L TT+ + E +
Sbjct: 433 LEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD--SVEGNA 490
Query: 178 GQLFTHLGRMALEFNRLASKVH--KNE--QRTSILQTLCEQLRKENEALKAKLDKGLEQR 233
++ +M E RL+ KV +NE Q LQ C+ L K+ KA+L+K +E
Sbjct: 491 SKIL----KMEKENQRLSKKVEILENEIVQEKQSLQN-CQNLSKDLMKEKAQLEKTIETL 545
Query: 234 DQAAER----LREENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTA-G 288
+ +ER L +EN L + + S +Q++ ++A
Sbjct: 546 RENSERQIKILEQENEHLNQTVSSL-------------------------RQRSQISAEA 580
Query: 289 KVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQ 348
+V ++ EK+ K+L + E + + R +K++ E E ++ +L+ +
Sbjct: 581 RVKDI------EKENKILHESIKETSSKLSKIEFEKRQIKKELEH-YKEKGERAEELENE 633
Query: 349 VTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQ 408
+ LE E E Q+ L + KIE E + +L E ++L++ + D LT Q
Sbjct: 634 LHHLEKENELLQKKITN-LKITCEKIEALEQENSELERENRKLKKTL----DSFKNLTFQ 688
Query: 409 REYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKI 468
E EKE +L+ EE L ++ S A S + A L +EL ++ E LK+ +++
Sbjct: 689 LESLEKENSQLD---EENLELRRNVESLKCA--SMKMAQLQLENKELESEKEQLKKGLEL 743
Query: 469 FEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDE----EKAREALRQQ 524
+ F++ ER+ + L + ++LQ + SN +++ + E E + L++
Sbjct: 744 LKASFKK----TERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKN 799
Query: 525 KRKAKASGER 534
+ K S +R
Sbjct: 800 LEELKISSKR 809
Score = 65.9 bits (159), Expect = 1e-10
Identities = 115/528 (21%), Positives = 218/528 (41%), Gaps = 55/528 (10%)
Query: 20 EASAAFERLVKENSRLKEKMQGIKMLGELLEESQMEATRLRQKAEELVKDNELLPPPSPS 79
E L KEN L++K+ +K+ E +E + E + L ++ +L K + +
Sbjct: 629 ELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQ 688
Query: 80 LGSFDPL-AELTGKDSNVTASPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSPES 138
L S + ++L ++ + + + C S K A +Q S + E+
Sbjct: 689 LESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK------EQLKKGLE 742
Query: 139 SSHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKV 198
A+ L L + QRL+ TL ++ QL + L + +E L
Sbjct: 743 LLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ--QLESELQDLEMENQTL---- 796
Query: 199 HKNEQRTSILQTLCEQLRKENEALK---AKLDKGLEQRDQAAERLREENLELKKLLMSNG 255
KN + I EQL KEN++L+ ++L+K +Q ++ +RLR++ E+K +
Sbjct: 797 QKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ-AEIKDTTLEEN 855
Query: 256 NKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLE 315
N + G+ + E G + S V L EK+ K L ++ + ++
Sbjct: 856 NV-----KIGNLEKENKTLSKEIGIYKESC--------VRLKELEKENKELVKRATIDIK 902
Query: 316 VNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIE 375
+ S K + +Q +L + +L+K + E +Q D + L +SK+E
Sbjct: 903 TLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLE 962
Query: 376 ME-----ETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQ 430
E +E++ A L + Y Q L ++ + +K + L + +E +Q
Sbjct: 963 STLKKSLEIKEEKIAALEARLEESTNYNQQ----LRQELKTVKKNYEALKQRQDEERMVQ 1018
Query: 431 TPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEEL 490
SSPP + G ++ T ELLK + ++ E + + + EK+ L
Sbjct: 1019 ---SSPPIS-----GEDNKWERESQETTRELLKVKDRLIEVE-----RNNATLQAEKQAL 1065
Query: 491 KKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGERYHVE 538
K Q+++L+ Q AQ+ A ++ +L++Q + + VE
Sbjct: 1066 KTQLKQLETQNNNLQAQILAL---QRQTVSLQEQNTTLQTQNAKLQVE 1110
Score = 33.5 bits (75), Expect = 0.61
Identities = 68/359 (18%), Positives = 141/359 (39%), Gaps = 71/359 (19%)
Query: 50 EESQMEATRLRQKAEELVKDNELLPPPSPSLGSFDPLAELTGKDSNVTASPTAPACPSDK 109
+E+ E +++ + E+ ++N L +L + L +L +++N+ A A +
Sbjct: 1035 QETTRELLKVKDRLIEVERNNATLQAEKQALKT--QLKQLETQNNNLQAQILAL---QRQ 1089
Query: 110 PAPVQKPPSSGTSSEFEVVTPEEQNSPESSSHANAMALGPLPREDGNLMLHLQRLET-TL 168
+Q+ T+ + + + +NS +S + M ++ L++ LE
Sbjct: 1090 TVSLQE---QNTTLQTQNAKLQVENSTLNSQSTSLM------NQNAQLLIQQSSLENENE 1140
Query: 169 SVCAEEPDHGQLFTHL----GRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKA 224
SV E D L+ L ++ L R AS+ + L++ + L E+ L+
Sbjct: 1141 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED 1200
Query: 225 KLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRP-------------------- 264
+ ++ L+Q+ Q + + +E +K+L+ N N E +
Sbjct: 1201 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE 1260
Query: 265 ---------------GSPKMEGTGKKAVAGQ-----QQASVTAGKVPEVVALGAAEK--- 301
+ K+E T +A + QQ +T+ K+ L + K
Sbjct: 1261 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL 1320
Query: 302 ---------KVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTD 351
+++ L Q LLE N + F ++QY K+ ELR++ L++++ D
Sbjct: 1321 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMD 1379
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 69.7 bits (169), Expect = 8e-12
Identities = 92/410 (22%), Positives = 177/410 (43%), Gaps = 54/410 (13%)
Query: 156 NLMLHLQRLETTLSVCAEEPDHGQLFTHLG--RMALEFNRLASKVHKNE------QRTSI 207
N+ LHL+RL E +H + L R L F AS ++ +RT
Sbjct: 192 NMALHLKRL------IDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTES 245
Query: 208 LQTLCEQL---RKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGN--KEGASG 262
Q L +L + + L+ +L++ EQ + L + +ELK+L N N + S
Sbjct: 246 RQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSA 305
Query: 263 RPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQ 322
R +++ +KAV + S + + + + +V+ L++ LLE +
Sbjct: 306 RMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLED 365
Query: 323 HFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKL-----LLAKSKIEME 377
+ + K+ EL ++ L+ ++ D+E ER+ ++ + + L K M+
Sbjct: 366 QLEGTRAR-SDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 424
Query: 378 ET-----DKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQ-EKEIQRLNKALEEALSIQT 431
E+ + EQ++ ++ K L +++ LT R + E E Q L K +EE
Sbjct: 425 ESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEEL----- 479
Query: 432 PPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRER-------MN 484
T S EG + + K E +N+ L ++V+I E + +E+ + +
Sbjct: 480 -----RTTVDSVEGNASKILKME--KENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLM 532
Query: 485 EEKEELKKQVEKLQAQVTLSNAQLKAFKDE-EKAREALRQQKRKAKASGE 533
+EK +L+K +E L+ S Q+K + E E + + +++++ S E
Sbjct: 533 KEKAQLEKTIETLREN---SERQIKILEQENEHLNQTVSSLRQRSQISAE 579
Score = 69.7 bits (169), Expect = 8e-12
Identities = 120/521 (23%), Positives = 213/521 (40%), Gaps = 68/521 (13%)
Query: 22 SAAFERLVKENSRLKEKMQGIKMLGELLEESQMEATRLRQKAEELVKDNELLPPPSPSLG 81
S L KEN +LK K L + +ME R+K EEL+++N L
Sbjct: 374 SDKLHELEKENLQLKAK----------LHDMEMERDMDRKKIEELMEENMTLEMAQKQ-- 421
Query: 82 SFDPLAELTGKDSNVTASPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSPESSSH 141
S D L + ++ + + + + P E +T
Sbjct: 422 SMDESLHLGWELEQIS-----------RTSELSEAPQKSLGHEVNELT------------ 458
Query: 142 ANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKVH-- 199
+ L L E+ +L ++ L TT V + E + ++ +M E RL+ KV
Sbjct: 459 --SSRLLKLEMENQSLTKTVEELRTT--VDSVEGNASKIL----KMEKENQRLSKKVEIL 510
Query: 200 KNE--QRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAER----LREENLELKKLLMS 253
+NE Q LQ C+ L K+ KA+L+K +E + +ER L +EN L + + S
Sbjct: 511 ENEIVQEKQSLQN-CQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSS 569
Query: 254 NGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSEL 313
+ S +E K + T+ K+ ++ KK +++ E
Sbjct: 570 LRQRSQISAEARVKDIEKENKIL---HESIKETSSKLSKIEFEKRQIKKELEHYKEKGER 626
Query: 314 LEVNKQWDQHFRSMKQQYEQKITELR---QKLADLQKQVTDLEAEREQKQRDFDRKLLLA 370
E + H + ++KIT L+ +K+ L+++ ++LE E + ++ D L
Sbjct: 627 AEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLT 686
Query: 371 KSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQ 430
++E E + QL E ELR+ V+ L+ S Q + + KE++ + L++ L +
Sbjct: 687 -FQLESLEKENSQLDEENLELRRNVESLK-CASMKMAQLQLENKELESEKEQLKKGLEL- 743
Query: 431 TPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEEL 490
S T G + Q L E ++++ E + Q + + + + EEL
Sbjct: 744 LKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEEL 803
Query: 491 K------KQVEKLQAQVTLSNAQLKAFKDE-EKAREALRQQ 524
K +Q+EK + +QL+ K + EK + LRQQ
Sbjct: 804 KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Score = 69.3 bits (168), Expect = 1e-11
Identities = 95/411 (23%), Positives = 174/411 (42%), Gaps = 66/411 (16%)
Query: 156 NLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQL 215
NL L+ LE S EE L R + K+ + + L++ EQL
Sbjct: 684 NLTFQLESLEKENSQLDEEN------LELRRNVESLKCASMKMAQLQLENKELESEKEQL 737
Query: 216 RKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRPGSPKMEGTGKK 275
+K E LKA K E+ + + + L EN L+K L N NK+ +E +
Sbjct: 738 KKGLELLKASFKK-TERLEVSYQGLDIENQRLQKTL-ENSNKKIQQLESELQDLEMENQT 795
Query: 276 AVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKI 335
++ +++ ++ ++ EK+ K LEQ+ S+L + KQ ++ + ++QQ E K
Sbjct: 796 LQKNLEELKISSKRLEQL------EKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKD 849
Query: 336 TELRQ---KLADLQKQ-----------------VTDLEAEREQ--KQRDFDRKLLLA--- 370
T L + K+ +L+K+ + +LE E ++ K+ D K L+
Sbjct: 850 TTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLRE 909
Query: 371 -----KSKIEMEETDKEQLTAEAKEL-RQKVKYLQDQLSPLTRQREYQEKEIQRLNKALE 424
K K + D E+LT E +++ K + L D+ S R + + K L K+LE
Sbjct: 910 DLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLE 969
Query: 425 EALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQ--RERSDRER 482
+ A R +E N+ L+Q++K +++++ ++R D ER
Sbjct: 970 ---------------IKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEER 1014
Query: 483 MNEEKEELKKQVEKLQAQVTLSNAQLKAFKDE----EKAREALRQQKRKAK 529
M + + + K + + + +L KD E+ L+ +K+ K
Sbjct: 1015 MVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALK 1065
Score = 66.2 bits (160), Expect = 9e-11
Identities = 126/550 (22%), Positives = 229/550 (41%), Gaps = 92/550 (16%)
Query: 20 EASAAFERLVKENSRLKEKMQGIKMLGELLEE----------------SQMEATRLRQ-K 62
E + ++L E SR KE++ I+ +EE Q+E TR R K
Sbjct: 317 EKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDK 376
Query: 63 AEELVKDNELLPPPSPSLGSFDPLAELTGKDSNVTASPTAPACPSDKPAPVQKPPSSGTS 122
EL K+N L L + ++ K + K + + + G
Sbjct: 377 LHELEKENLQL---KAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQS-MDESLHLGWE 432
Query: 123 SEFEVVTPEEQNSPESS-----SHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDH 177
E T E +P+ S + + L L E+ +L ++ L TT+ + E +
Sbjct: 433 LEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD--SVEGNA 490
Query: 178 GQLFTHLGRMALEFNRLASKVH--KNE--QRTSILQTLCEQLRKENEALKAKLDKGLEQR 233
++ +M E RL+ KV +NE Q LQ C+ L K+ KA+L+K +E
Sbjct: 491 SKIL----KMEKENQRLSKKVEILENEIVQEKQSLQN-CQNLSKDLMKEKAQLEKTIETL 545
Query: 234 DQAAER----LREENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTA-G 288
+ +ER L +EN L + + S +Q++ ++A
Sbjct: 546 RENSERQIKILEQENEHLNQTVSSL-------------------------RQRSQISAEA 580
Query: 289 KVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQ 348
+V ++ EK+ K+L + E + + R +K++ E E ++ +L+ +
Sbjct: 581 RVKDI------EKENKILHESIKETSSKLSKIEFEKRQIKKELEH-YKEKGERAEELENE 633
Query: 349 VTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQ 408
+ LE E E Q+ L + KIE E + +L E ++L++ + D LT Q
Sbjct: 634 LHHLEKENELLQKKITN-LKITCEKIEALEQENSELERENRKLKKTL----DSFKNLTFQ 688
Query: 409 REYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKI 468
E EKE +L+ EE L ++ S A S + A L +EL ++ E LK+ +++
Sbjct: 689 LESLEKENSQLD---EENLELRRNVESLKCA--SMKMAQLQLENKELESEKEQLKKGLEL 743
Query: 469 FEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDE----EKAREALRQQ 524
+ F++ ER+ + L + ++LQ + SN +++ + E E + L++
Sbjct: 744 LKASFKK----TERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKN 799
Query: 525 KRKAKASGER 534
+ K S +R
Sbjct: 800 LEELKISSKR 809
Score = 64.7 bits (156), Expect = 2e-10
Identities = 113/534 (21%), Positives = 221/534 (41%), Gaps = 68/534 (12%)
Query: 20 EASAAFERLVKENSRLKEKMQGIKMLGELLEESQMEATRLRQKAEELVKDNELLPPPSPS 79
E L KEN L++K+ +K+ E +E + E + L ++ +L K + +
Sbjct: 629 ELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQ 688
Query: 80 LGSFDPL-AELTGKDSNVTASPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSPES 138
L S + ++L ++ + + + C S K A +Q S + E+
Sbjct: 689 LESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK------EQLKKGLE 742
Query: 139 SSHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKV 198
A+ L L + QRL+ TL ++ QL + L + +E L
Sbjct: 743 LLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ--QLESELQDLEMENQTL---- 796
Query: 199 HKNEQRTSILQTLCEQLRKENEALK---AKLDKGLEQRDQAAERLREENLELKKLLMSNG 255
KN + I EQL KEN++L+ ++L+K +Q ++ +RLR++ E+K +
Sbjct: 797 QKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ-AEIKDTTLEEN 855
Query: 256 NKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLE 315
N + + ++ + T K E+ + ++K LE++ EL++
Sbjct: 856 NVK------------------IGNLEKENKTLSK--EIGIYKESCVRLKELEKENKELVK 895
Query: 316 VNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQR------DFDRKLLL 369
+ ++++ + + +Q DL+K +LE K+R D + L
Sbjct: 896 RATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKL 955
Query: 370 AKSKIEME-----ETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALE 424
+SK+E E +E++ A L + Y Q L ++ + +K + L + +
Sbjct: 956 LESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQ----LRQELKTVKKNYEALKQRQD 1011
Query: 425 EALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMN 484
E +Q SSPP + G ++ T ELLK + ++ E + + +
Sbjct: 1012 EERMVQ---SSPPIS-----GEDNKWERESQETTRELLKVKDRLIEVE-----RNNATLQ 1058
Query: 485 EEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGERYHVE 538
EK+ LK Q+++L+ Q AQ+ A ++ +L++Q + + VE
Sbjct: 1059 AEKQALKTQLKQLETQNNNLQAQILAL---QRQTVSLQEQNTTLQTQNAKLQVE 1109
Score = 33.5 bits (75), Expect = 0.61
Identities = 68/359 (18%), Positives = 141/359 (39%), Gaps = 71/359 (19%)
Query: 50 EESQMEATRLRQKAEELVKDNELLPPPSPSLGSFDPLAELTGKDSNVTASPTAPACPSDK 109
+E+ E +++ + E+ ++N L +L + L +L +++N+ A A +
Sbjct: 1034 QETTRELLKVKDRLIEVERNNATLQAEKQALKT--QLKQLETQNNNLQAQILAL---QRQ 1088
Query: 110 PAPVQKPPSSGTSSEFEVVTPEEQNSPESSSHANAMALGPLPREDGNLMLHLQRLET-TL 168
+Q+ T+ + + + +NS +S + M ++ L++ LE
Sbjct: 1089 TVSLQE---QNTTLQTQNAKLQVENSTLNSQSTSLM------NQNAQLLIQQSSLENENE 1139
Query: 169 SVCAEEPDHGQLFTHL----GRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKA 224
SV E D L+ L ++ L R AS+ + L++ + L E+ L+
Sbjct: 1140 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED 1199
Query: 225 KLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRP-------------------- 264
+ ++ L+Q+ Q + + +E +K+L+ N N E +
Sbjct: 1200 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE 1259
Query: 265 ---------------GSPKMEGTGKKAVAGQ-----QQASVTAGKVPEVVALGAAEK--- 301
+ K+E T +A + QQ +T+ K+ L + K
Sbjct: 1260 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL 1319
Query: 302 ---------KVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTD 351
+++ L Q LLE N + F ++QY K+ ELR++ L++++ D
Sbjct: 1320 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMD 1378
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 69.3 bits (168), Expect = 1e-11
Identities = 87/377 (23%), Positives = 162/377 (42%), Gaps = 52/377 (13%)
Query: 192 NRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLE-QRDQAAERLREENLELKKL 250
N ++ + E + S L+ + +Q KEN L+ +L + + Q + A + + +E+K
Sbjct: 326 NERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDT 385
Query: 251 LMSNGNKE-----------GASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVA-LGA 298
+++ + A+G + E K+ + + K+ ++ L
Sbjct: 386 KIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSK 445
Query: 299 AEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQ 358
E ++ L+ + L N QH +K+ +T Q+ A LQ +V L E+
Sbjct: 446 KESELLALQTKLETLSNQNSDCKQHIEVLKES----LTAKEQRAAILQTEVDALRLRLEE 501
Query: 359 KQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELR-------QKVKYLQDQLSPLTRQREY 411
K+ ++K + E +K L E ++++ +K+ LQ ++ L Q
Sbjct: 502 KESFLNKKTKQLQDLTE----EKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRD 557
Query: 412 QEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEE 471
++K++ L ++ S+QT S+ TA + E A L K+ ++ E LK+Q
Sbjct: 558 KDKQLTNLKDRVK---SLQTDSSNTDTALATLEEA--LSEKERII---ERLKEQ------ 603
Query: 472 DFQRERSDRERMNE------EKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQK 525
RER DRER+ E E ++LK++V LQA++T + L K E + A K
Sbjct: 604 ---RERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLK-EHASSLASAGLK 659
Query: 526 RKAKASGERYHVEPHPE 542
R +K +E E
Sbjct: 660 RDSKLKSLEIAIEQKKE 676
Score = 37.0 bits (84), Expect = 0.055
Identities = 57/255 (22%), Positives = 100/255 (39%), Gaps = 48/255 (18%)
Query: 285 VTA-GKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLA 343
VTA G P + + G + V Q L + SM +Q +
Sbjct: 95 VTAMGSSPNIASAGLSHTDVLSYTDQHGGLTGSSHHHHHQVPSMLRQVRDST------ML 148
Query: 344 DLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLS 403
DLQ Q+ +L+ E + +++ D K S + +T + E K+ R K ++S
Sbjct: 149 DLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTF---WSPELKKERVLRKEEAARMS 205
Query: 404 PLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQ---NE 460
L Q +E Q L L+IQ + EL TQ N
Sbjct: 206 VLKEQMRVSHEENQHLQ------LTIQA-------------------LQDELRTQRDLNH 240
Query: 461 LLKQQ----------VKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKA 510
LL+Q+ +++ EE+F+R +++ +R +E L+K +E+++ ++ L A
Sbjct: 241 LLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNA 300
Query: 511 FKDEEKAREALRQQK 525
+ K + Q K
Sbjct: 301 RDESIKKLLEMLQSK 315
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 68.9 bits (167), Expect = 1e-11
Identities = 75/356 (21%), Positives = 167/356 (46%), Gaps = 28/356 (7%)
Query: 183 HLGRMALEFN-RLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRD---QAAE 238
HLG+ + +L ++V +NE + Q E++ ++ E ++ +K EQ + + E
Sbjct: 330 HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 389
Query: 239 RLREENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGA 298
++RE+ ++++ KE R E K ++Q + K ++
Sbjct: 390 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM----RRQEEMMWEKEEKI----- 440
Query: 299 AEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQ 358
E + KM EQ++ E +Q ++ R +++ EQ+ RQ+ + E+E+
Sbjct: 441 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE---------EKIREQEE 491
Query: 359 KQRDFDRKLLLAKSKI-EMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQ 417
K R+ + K+ + KI E E+ +E+ E +E+ ++ + +++Q + RQ+E ++ +
Sbjct: 492 KIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ-EEIWRQKEKIHEQEE 550
Query: 418 RLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRER 477
++ K EE + Q + +++++ Q E +++Q + E + +
Sbjct: 551 KIRKQ-EEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQ 609
Query: 478 SDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGE 533
E+M E++E++ +Q EK+Q Q Q + +++EK +R+Q+ K + E
Sbjct: 610 EQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEK---KIREQEEKIREQEE 662
Score = 68.2 bits (165), Expect = 2e-11
Identities = 103/472 (21%), Positives = 204/472 (43%), Gaps = 62/472 (13%)
Query: 93 DSNVTASPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSPESSSHANAMALGPLPR 152
D + +P+ SD +K ++GT+ E T +SPE A+ L R
Sbjct: 130 DHHPQTNPSVGTAASDTK---KKKINNGTNPE--TTTSGGCHSPEDEQKASHQHQEALRR 184
Query: 153 EDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMAL-----EFNRLASKVHKN------ 201
E L+ T+ + + Q+ + + A+ E L S++H +
Sbjct: 185 E-------LEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGE 237
Query: 202 -EQRTSILQT-------LCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELK-KLLM 252
EQ S + T E+L KE +AL +L + E L+E+N +L+ KL +
Sbjct: 238 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTI----TDEELKEKNAKLQEKLQL 293
Query: 253 SNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQ--- 309
K K + K + QQQ A + + + +A+ + ++ E +
Sbjct: 294 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWN 353
Query: 310 RSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAE-REQKQRDFDRKLL 368
R + K W Q + Q++E+KI E +K+ + ++++ + E + R Q++ ++++
Sbjct: 354 RLNQQQEEKMWRQEEKI--QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 411
Query: 369 LAKSKIEMEETDKEQLTAEAK--ELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEA 426
+ + + M E +++ E E +K++ L++++ + RE +EK + EE
Sbjct: 412 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE------EEK 465
Query: 427 LSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNE--LLKQQVKIFEEDFQRERSDRERMN 484
+ Q E + ++E + + E + +Q+ KI E++ RE R+
Sbjct: 466 IREQEKRQEQEAKMWRQEEK--IREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQ--- 520
Query: 485 EEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGERYH 536
E+EE+ +Q EK++ Q + + K + EEK +R+Q+ K E+ H
Sbjct: 521 -EQEEMWRQEEKIREQEEIWRQKEKIHEQEEK----IRKQEEKMWRQEEKMH 567
Score = 56.6 bits (135), Expect = 7e-08
Identities = 66/355 (18%), Positives = 159/355 (44%), Gaps = 49/355 (13%)
Query: 186 RMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDK--GLEQRDQAAERLREE 243
+M + + K K ++ ++ E++R++ E + K +K LE++ E++RE+
Sbjct: 397 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 456
Query: 244 NL----ELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAA 299
E K ++ A K+ +K +++ K+ E +
Sbjct: 457 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREE 516
Query: 300 EKKVKMLEQQRSE--LLEVNKQWDQHFRSMKQQ-----YEQKITELRQKLADLQKQVTDL 352
EK+ + E R E + E + W Q + +Q+ E+K+ +K+ D ++++ +
Sbjct: 517 EKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQ 576
Query: 353 EAE---REQKQRDFDRKLLLAKSKI----EMEETDKEQLTAEAKELRQKVKYLQDQLSPL 405
E + +E+K R+ + K+ + KI EM + +E++ + +++ ++ + +Q+Q +
Sbjct: 577 EEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKM 636
Query: 406 TRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQ 465
RQ E++I+ K + E +++++ Q E++++Q
Sbjct: 637 RRQ----EEKIREQEKKIRE-------------------------QEEKIREQEEMMQEQ 667
Query: 466 VKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREA 520
+ E ++ E+M E++E++++Q EK+ Q Q + ++ ++ EA
Sbjct: 668 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 68.6 bits (166), Expect = 2e-11
Identities = 128/592 (21%), Positives = 236/592 (39%), Gaps = 89/592 (15%)
Query: 20 EASAAFERLVKENSR-------LKEKMQGIKMLGELLEESQMEAT-------RLRQKAEE 65
E A +RL K+N L EK++ ++ L L E++ +E LR A+
Sbjct: 401 ELGLAVKRLEKQNLEKDQVNKDLTEKLEALESL-RLQEQAALETEDGEGLQQTLRDLAQA 459
Query: 66 LVKDNELLPPPSPSLGSFDPL-AELTGKDSNVTASPTAPACPSDKPAPVQKP-PSSGTSS 123
++ D+E S S + D L G T SP + P +P + P P+ SS
Sbjct: 460 VLSDSESGVQLSGSERTADASNGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACSDSS 519
Query: 124 EFEVVTPE------EQNSPESSSHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDH 177
++ + A+ LG L ++ + + LE L ++ D
Sbjct: 520 TLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDG 579
Query: 178 GQLFTHLGRMALEFNRLASKVHKNEQRT-----SILQTLCEQLRKENEALKAKLDKGLEQ 232
+ ++ R A+++ E+ + Q E+LR+E E L+A ++ Q
Sbjct: 580 AMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQ 639
Query: 233 RDQAAERLRE-------------------ENLELKKLLMSNGNKE--GASGRPGSPKMEG 271
RD+ E + E LE K+ +++ E A R +
Sbjct: 640 RDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDML 699
Query: 272 TGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQH-------- 323
+KA + AG+V +++ + L+ S+L +N+ Q
Sbjct: 700 QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLV 759
Query: 324 ---------FRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKI 374
+ ++Q EQ+ T R++ Q+++ +L E+E ++ + L +A+
Sbjct: 760 AQLEEEKSALQGRQRQAEQEATVAREE----QERLEELRLEQEVARQGLEGSLRVAEQAQ 815
Query: 375 EMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEA-------- 426
E E L E +L++++ L QLS ++ E +E QR +ALE A
Sbjct: 816 EALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALA 875
Query: 427 -----LSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRE 481
L++Q + S E L K+ L + L + Q ++ + + +RE+ + E
Sbjct: 876 KEHAGLAVQLVAAEREGRTLSEEATRLRLEKEAL--EGSLFEVQRQLAQLEARREQLEAE 933
Query: 482 --RMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKAS 531
+ KE L ++ L+ Q+ + Q KA D+E + L Q +R+A+AS
Sbjct: 934 GQALLLAKETLTGELAGLRQQIIAT--QEKASLDKELMAQKLVQAEREAQAS 983
Score = 61.6 bits (148), Expect = 2e-09
Identities = 108/471 (22%), Positives = 184/471 (39%), Gaps = 107/471 (22%)
Query: 119 SGTSSEFEVVTPEEQNSPESSSHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHG 178
SG E E E Q E+ A A L +E L + L E +EE
Sbjct: 844 SGREQELEQARREAQRQVEALERA-AREKEALAKEHAGLAVQLVAAEREGRTLSEEAT-- 900
Query: 179 QLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEAL---------------- 222
R+ LE L + + +++ + L+ EQL E +AL
Sbjct: 901 -------RLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQ 953
Query: 223 -------KAKLDKGL------EQRDQAAERLREENLELKKLLMSNGNKEGASGRPGSPKM 269
KA LDK L + +A LRE+ ++ L ++ A+ R
Sbjct: 954 QIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRE----- 1008
Query: 270 EGTGKKAVAGQQQASVTAGKVPEVVALGAAEKK-----VKMLEQQRSELLEVNKQWDQHF 324
+A Q Q+ + + E++A AEK+ + L+Q+R E L + + Q
Sbjct: 1009 ----LEAERAQLQSQLQREQ-EELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQA 1063
Query: 325 RSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQL 384
S+K E + T L +KL + + + E E+++RD A+S+ E + + L
Sbjct: 1064 LSLK---ESEKTALSEKLMGTRHSLATISLEMERQKRD-------AQSRQEQDRSTVNAL 1113
Query: 385 TAEAKELR-----------QKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPP 433
T+E ++LR Q+V+ LQ+Q L +QR+ +E + L L
Sbjct: 1114 TSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLL------- 1166
Query: 434 SSPPTAFGSPEGAGALLRKQELVTQN---------ELLKQQVKIFEEDFQRERSDRERMN 484
E A LR++ L Q E+ +Q+ +RE +
Sbjct: 1167 ----------EDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALR 1216
Query: 485 EEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKA--KASGE 533
EEL+ V+K +++ LK ++++ + AL ++ R A K +GE
Sbjct: 1217 RSNEELRSAVKKAESE----RISLKLANEDKEQKLALLEEARTAVGKEAGE 1263
Score = 50.8 bits (120), Expect = 4e-06
Identities = 73/333 (21%), Positives = 150/333 (45%), Gaps = 35/333 (10%)
Query: 194 LASKVHKNEQRTSILQTLCEQLR------KENE-ALKAK---LDKGLEQRDQAAERLREE 243
L +V +E + LQ E+L +E+E AL+ K L + L Q + R++
Sbjct: 1689 LQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDK 1748
Query: 244 NLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKV 303
NL L+K L + + R + ++A++ ++ S + G+ + + A+ ++
Sbjct: 1749 NLHLQKALTACEHD-----RQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLEL 1803
Query: 304 KMLE-----QQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQ 358
+ +E QQ E+L ++ + + Q+ + + L+++L LQ+ + LEAE+ +
Sbjct: 1804 QRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKRE 1863
Query: 359 KQRDFDRKLLLAKSKIEMEET----DKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEK 414
+R L L K ++ + T ++E+L + +R + + +L E +
Sbjct: 1864 VERS---ALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAE--KGRLDRTLTGAELELA 1918
Query: 415 EIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQ 474
E QR + LE + + SP + A ++ EL + E L+ E +
Sbjct: 1919 EAQRQIQQLEAQVVVLEQSHSP-----AQLEVDAQQQQLELQQEVERLRSAQAQTERTLE 1973
Query: 475 -RERSDRERMNEEKEELKKQVEKLQAQVTLSNA 506
RER+ R+R+ +E++ +LQ ++ S+A
Sbjct: 1974 ARERAHRQRVRGLEEQVSTLKGQLQQELRRSSA 2006
Score = 50.4 bits (119), Expect = 5e-06
Identities = 77/364 (21%), Positives = 149/364 (40%), Gaps = 55/364 (15%)
Query: 187 MALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLE 246
+A E LA ++ E+ L +LR E EAL+ L + Q Q R + E
Sbjct: 874 LAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAE 933
Query: 247 LKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKML 306
+ LL++ KE +G ++ G ++ +A Q++AS+
Sbjct: 934 GQALLLA---KETLTG-----ELAGLRQQIIATQEKASLDK------------------- 966
Query: 307 EQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRK 366
E +L++ ++ R + +E+ + L++ + + +LEAER Q Q R+
Sbjct: 967 ELMAQKLVQAEREAQASLREQRAAHEEDLQRLQR---EKEAAWRELEAERAQLQSQLQRE 1023
Query: 367 LLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEA 426
+E +L AE +EL +++ LQ + E ++++ L ++ + A
Sbjct: 1024 ----------QEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTA 1073
Query: 427 LSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRE----- 481
LS + + A S E +K++ ++ E + V + + R+ RE
Sbjct: 1074 LSEKLMGTRHSLATISLE---MERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAA 1130
Query: 482 ------RMNEEKEELKKQVEKLQAQVTLSNAQLKAFKD-EEKAREALRQQKRKAKASGER 534
R+ E+ +L KQ + + QL+ +D + R L + +RK + S E
Sbjct: 1131 HAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEG 1190
Query: 535 YHVE 538
V+
Sbjct: 1191 REVQ 1194
Score = 43.5 bits (101), Expect = 6e-04
Identities = 65/326 (19%), Positives = 133/326 (40%), Gaps = 29/326 (8%)
Query: 213 EQLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRPGSPKMEGT 272
++LR + AL +L + +RD A R R+ K + S + GR +
Sbjct: 1526 DELRTQTSALNRQLAEMEAERDSATSRARQLQ---KAVAESEEARRSVDGRL-------S 1575
Query: 273 GKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYE 332
G +A Q+ SV + L + L+ SE L +++ ++ + + E
Sbjct: 1576 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESE-LRASQEKISKMKANETKLE 1634
Query: 333 QKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELR 392
L++ L + + LE +R + + L +S++ + + + A+A+ L+
Sbjct: 1635 GDKRRLKEVLDASESRTVKLELQRRSLEGE------LQRSRLGLSDRE-----AQAQALQ 1683
Query: 393 QKVKYLQDQLSPLTRQREYQEKEIQRLNKAL----EEALSIQTPPSSPPTAFGSPEGAGA 448
+V LQ Q++ + + ++RLN AL E +++ A +
Sbjct: 1684 DRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLN 1743
Query: 449 LLRKQELVTQNEL--LKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVT-LSN 505
R + L Q L + ++ +E R ++ L +QV+ L+ +V L
Sbjct: 1744 STRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLEL 1803
Query: 506 AQLKAFKDEEKAREALRQQKRKAKAS 531
+++A ++ RE LRQ++ A+
Sbjct: 1804 QRVEAEGQLQQLREVLRQRQEGEAAA 1829
Score = 42.0 bits (97), Expect = 0.002
Identities = 81/373 (21%), Positives = 142/373 (38%), Gaps = 68/373 (18%)
Query: 176 DHGQLFTHLGRMALEFNRLAS----KVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLE 231
D L + + L RL K N+ T L+ L +E AL+ + +GL+
Sbjct: 391 DKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLQ 450
Query: 232 Q--RDQAAERLR--EENLEL----KKLLMSNGNKEGASGR--PGSPKMEGTGKKAVAGQQ 281
Q RD A L E ++L + SNG+ G SG+ P P+ G+ +
Sbjct: 451 QTLRDLAQAVLSDSESGVQLSGSERTADASNGSLRGLSGQRTPSPPRRSSPGRGRSPRRG 510
Query: 282 QASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQK 341
+ + + A K+ ++ R +YE +
Sbjct: 511 PSPACSDSSTLALIHSALHKRQLQVQDMRG------------------RYEAS----QDL 548
Query: 342 LADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQ 401
L L+KQ++D E+ER R + +L + K + E E + LR + L +
Sbjct: 549 LGTLRKQLSDSESER----RALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSRE 604
Query: 402 LSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNEL 461
S L + +++ + L + E+ + Q +EL Q +
Sbjct: 605 KSNLAHSLQVAQQQAEELRQEREKLQAAQ----------------------EELRRQRDR 642
Query: 462 LKQQVKIFEEDFQRERSDRERMNEEKEEL--KKQV---EKLQAQVTLSNAQL-KAFKDEE 515
L+++ + +D R R + ER + + E+L K+ V E ++ + LS A L + E
Sbjct: 643 LEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAE 702
Query: 516 KAREALRQQKRKA 528
KA A K +A
Sbjct: 703 KAEVAEALTKAEA 715
Score = 37.0 bits (84), Expect = 0.055
Identities = 45/214 (21%), Positives = 98/214 (45%), Gaps = 46/214 (21%)
Query: 318 KQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAER-----------------EQKQ 360
+++ Q RS +++ + ELR + + L +Q+ ++EAER E+ +
Sbjct: 1512 REFLQELRSAQRERD----ELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEAR 1567
Query: 361 RDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLN 420
R D +L ++++ ++E E + +E R + DQ++ L R + E E++
Sbjct: 1568 RSVDGRLSGVQAELALQE---ESVRRSERERRATL----DQVATLERSLQATESELRASQ 1620
Query: 421 KALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNE----LLKQQVKIFEEDFQRE 476
+ + + + +T + G R +E++ +E L+ Q + E + QR
Sbjct: 1621 EKISKMKANET------------KLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRS 1668
Query: 477 RSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKA 510
R + + L+ +V+ LQ QV +++++KA
Sbjct: 1669 RLGLSDREAQAQALQDRVDSLQRQV--ADSEVKA 1700
Score = 32.0 bits (71), Expect = 1.8
Identities = 32/164 (19%), Positives = 80/164 (48%), Gaps = 15/164 (9%)
Query: 365 RKLLLAKSKIEMEETDKEQLTAEAKE---LRQKVKYLQDQLSPLTRQREYQEKEIQRLNK 421
R L +S + + T+ L + +E L+Q++ ++D L+ +R+ + +++
Sbjct: 57 RNLSQPESPVLLPATEMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSE 116
Query: 422 ALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNE----LLKQQVKIFEEDFQRER 477
LE+AL ++ P + E G + + EL Q + +++++ ++E QR+
Sbjct: 117 RLEQALRLE------PGELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEGQQRQA 170
Query: 478 SDRERMNEEKEELKKQVEKLQAQVTLSNAQL--KAFKDEEKARE 519
+R+ + + KK+ +L+ Q+ + +L + +D E +++
Sbjct: 171 QLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQD 214
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 68.6 bits (166), Expect = 2e-11
Identities = 107/461 (23%), Positives = 195/461 (42%), Gaps = 64/461 (13%)
Query: 108 DKPAPVQKPPSSGTSSEFEVVTPEEQNSPESSSHANAMALGPLPREDGNLMLHLQRLETT 167
+K ++ P G+ E +V E+ + ES M+L ++G + + E
Sbjct: 189 EKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSL-----KNGQISSEEPKQEEE 243
Query: 168 LSVCAEEPDHGQLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLD 227
++E H + + E R + E+R I +++ E ++A+
Sbjct: 244 REQGSDEISHHEKMEEEDKERAEAERARLEA---EERERIKAEQDKKIADERARIEAEEK 300
Query: 228 KGLEQRD----QAAERLREENLEL--KKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQ 281
++R+ + ER+REE ++ + K A R + E K+A +Q
Sbjct: 301 AAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEE---KRAAEERQ 357
Query: 282 QASVTAGKVPEVVALGAAEK--KVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKIT--- 336
+ + E AE+ K K+ EQ+R++ LE K Q + ++ EQKI
Sbjct: 358 RIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKW 417
Query: 337 -------ELRQKLADLQKQV----TDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLT 385
E + + A L+KQ T ++A+RE+ Q D K K +I+ E+ K+
Sbjct: 418 VNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQED---KPTFKKEEIKDEKIKKD--- 471
Query: 386 AEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPT--AFGSP 443
KE +++VK D+ T + + + K E S +S T A G+P
Sbjct: 472 ---KEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAP 528
Query: 444 EGAGAL----LRKQELVTQNELL-----KQQVKIFE-EDFQRERSDRERMNEEKEELKKQ 493
+ LR++ T++E KQQ E E+ +++R +R ++ EE+E+ +KQ
Sbjct: 529 QVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQ 588
Query: 494 VEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGER 534
E A K ++EEK R ++R+A+A+ +R
Sbjct: 589 EE----------ADRKLREEEEKRRLKEEIERRRAEAAEKR 619
Score = 52.4 bits (124), Expect = 1e-06
Identities = 60/330 (18%), Positives = 144/330 (43%), Gaps = 31/330 (9%)
Query: 213 EQLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRPGSPKMEGT 272
E+L + E + +L + LE++ + + + +L L M N E + + K E +
Sbjct: 98 ERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET----TEKEEKS 153
Query: 273 GKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYE 332
+ + + + T K + AE+ K +++ E E K+ ++ E
Sbjct: 154 ESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVE 213
Query: 333 QKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKEL- 391
+K TE +++ + + + +E +++ + ++ +MEE DKE+ AE L
Sbjct: 214 EKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLE 273
Query: 392 ---RQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGA 448
R+++K QD+ R R E++ + EA +
Sbjct: 274 AEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERER----------------- 316
Query: 449 LLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQL 508
+R++E E +Q++K E+ +R +R+R+ EE++ ++ ++++ + + +
Sbjct: 317 -MREEEKRAAEE--RQRIK---EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 370
Query: 509 KAFKDEEKAREALRQQKRKAKASGERYHVE 538
+ + EE+ + + +QKR + +++ ++
Sbjct: 371 QRARAEEEEKAKVEEQKRNKQLEEKKHAMQ 400
Score = 42.7 bits (99), Expect = 0.001
Identities = 49/204 (24%), Positives = 99/204 (48%), Gaps = 8/204 (3%)
Query: 197 KVHKNEQRTSILQTLCEQLRKENEALKAKL--DKGLEQRDQAAERLREENLELKKLLMSN 254
K +++ +T++L+ E+ + +A + KL DK ++++ + +++ E K+ + S
Sbjct: 422 KAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSF 481
Query: 255 GNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGK--VPEVVALGAAEKKV-KMLEQQRS 311
+++ S E K + S G+ V A GA + + K LE+ R
Sbjct: 482 MDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRR 541
Query: 312 ELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAK 371
E + + + +Q+ ++ EL++K + +K + E E+ +KQ + DRKL +
Sbjct: 542 RRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLE--EEEQRRKQEEADRKLREEE 599
Query: 372 SKIEMEETDKEQLTAEAKELRQKV 395
K ++E + E+ AEA E RQK+
Sbjct: 600 EKRRLKE-EIERRRAEAAEKRQKM 622
Score = 30.0 bits (66), Expect = 6.8
Identities = 50/221 (22%), Positives = 88/221 (39%), Gaps = 44/221 (19%)
Query: 337 ELRQKLADLQKQVTDLEAEREQKQRDFD----------RKLLLAKSKIEMEE------TD 380
E R++L +++ LEAER QR+ D R+ + + + EE TD
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTD 64
Query: 381 KEQLTAEAKELRQKVKYL--------QDQLSPLTRQREYQEKEIQRLNKALEEALSIQTP 432
+ ++ A+ ++ K D+ + L R +E+ +RL +ALE
Sbjct: 65 QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFD-- 122
Query: 433 PSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKK 492
P+ + P R Q +NE +++ K R +R + EE E + K
Sbjct: 123 PTITDASLSLPS-----RRMQNDTAENETTEKEEK------SESRQERYEI-EETETVTK 170
Query: 493 QVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGE 533
+K + N K E+K +E ++K K + GE
Sbjct: 171 SYQKNDWRDAEEN------KKEDKEKEEEEEEKPKRGSIGE 205
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 68.2 bits (165), Expect = 2e-11
Identities = 59/245 (24%), Positives = 124/245 (50%), Gaps = 28/245 (11%)
Query: 281 QQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQ 340
QQ + +V E L +++++ + Q ++L+ +Q Q + + +Q+ +Q
Sbjct: 155 QQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQ 214
Query: 341 KLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKE--LRQKVKYL 398
+L Q+Q+ + +++Q+Q ++LLL + + ++++ +Q A+ ++ L Q+ L
Sbjct: 215 QLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQL 274
Query: 399 QDQLSPLTRQREYQEKEIQRLNKALEEAL---SIQTPPSSP-----------PTAFGSPE 444
Q QL L +Q + Q+++ Q+L + +E L +Q PP P P GS
Sbjct: 275 QQQLL-LQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGS-- 331
Query: 445 GAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLS 504
+QEL Q + L++Q ++ E Q +R + ++ EE ++L++Q+E+ Q Q+
Sbjct: 332 -------EQELEQQRQELERQQEL--ERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQ 382
Query: 505 NAQLK 509
QL+
Sbjct: 383 EVQLE 387
Score = 50.8 bits (120), Expect = 4e-06
Identities = 56/288 (19%), Positives = 132/288 (45%), Gaps = 26/288 (9%)
Query: 267 PKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRS 326
P +E + GQQQ S + + V + +++++ QQ+ ++ Q Q +
Sbjct: 114 PHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQ----QLQPQQVQEQQR 169
Query: 327 MKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTA 386
++QQ EQ T+ Q+ LQ+Q E+ Q+Q + L + +++ ++ ++Q
Sbjct: 170 LQQQQEQLQTQQAQEQQVLQQQ------EQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQL 223
Query: 387 EAKELRQKVKYL--QDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPE 444
+ ++ +Q+ + L Q QL L +Q + Q++ +Q+ L++ L Q +
Sbjct: 224 QQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQ 283
Query: 445 GAGALLRKQELVTQNELLKQQVKIFEEDFQRERSD-------------RERMNEEKEELK 491
++Q+L+ Q + QQ ++ + E + + + ++++EL+
Sbjct: 284 EQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELE 343
Query: 492 KQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGERYHVEP 539
+Q ++L+ Q QLK ++ ++ + L QQ+++ + + + P
Sbjct: 344 RQ-QELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTP 390
Score = 48.5 bits (114), Expect = 2e-05
Identities = 58/322 (18%), Positives = 144/322 (44%), Gaps = 50/322 (15%)
Query: 262 GRPGSPKMEGTGKKAVAGQQQ---------------ASVTAGKVPEVVALGAAEKKVKML 306
G PG + G + + +++ A V A ++ E G E +++ L
Sbjct: 35 GGPGPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQL 94
Query: 307 EQQ-------RSELLEVNKQWDQHFRSMKQQYEQKITELRQ---------------KLAD 344
EQQ + E L+ + + + +Q +Q++++L+Q +L
Sbjct: 95 EQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMH 154
Query: 345 LQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKE---LRQKVKYLQDQ 401
Q+Q+ + + +Q+ + +L +++ + +EQL + +E L+Q+ + LQ Q
Sbjct: 155 QQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQ 214
Query: 402 LSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNEL 461
L +Q + Q+++ Q+ + L++ + + A L++Q L Q
Sbjct: 215 -QLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQ 273
Query: 462 LKQQVKIFEEDFQRERSDRERMNEEKEELKKQ---------VEKLQAQVTLSNAQLKAFK 512
L+QQ+ + +++ +++ ++ + +++E+L++Q E+ + ++ L L + +
Sbjct: 274 LQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQ 333
Query: 513 DEEKAREALRQQKRKAKASGER 534
+ E+ R+ L +Q+ + +R
Sbjct: 334 ELEQQRQELERQQELERQQEQR 355
Score = 43.1 bits (100), Expect = 8e-04
Identities = 61/312 (19%), Positives = 132/312 (42%), Gaps = 39/312 (12%)
Query: 130 PEEQNSPESSSHANA---MALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGR 186
PE Q P+ + L P++DG L + E SV H +L L
Sbjct: 98 PEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSV-----HHQELKPELQL 152
Query: 187 MALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLE 246
M + +V + ++ + L Q +E + L+ + + ++Q + ++E L+
Sbjct: 153 MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQ 212
Query: 247 LKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKML 306
++LL + + +++ + + QQ + + ++L
Sbjct: 213 QQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQ-----------------GQLQQQLL 255
Query: 307 EQQRSEL----LEVNKQ-------WDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAE 355
+QQ+++L LE + Q + +QQ +Q + + +++L Q Q LE E
Sbjct: 256 QQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPE 315
Query: 356 REQK-QRDFDRKLLLAKSKIEM--EETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQ 412
E++ + + L ++ ++E +E +++Q +E RQ LQ++L L +Q E Q
Sbjct: 316 EEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQ 375
Query: 413 EKEIQRLNKALE 424
++++++ LE
Sbjct: 376 QQQLEQQEVQLE 387
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 67.8 bits (164), Expect = 3e-11
Identities = 54/314 (17%), Positives = 149/314 (47%), Gaps = 17/314 (5%)
Query: 214 QLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRPGSPKMEGTG 273
Q+R++ ++ + + EQ Q E+ + + ++ G G+ + +
Sbjct: 130 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 189
Query: 274 KKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQ 333
++ G+Q+ + G+ E +G E++++ E+Q E E ++ ++ ++Q ++
Sbjct: 190 QEGQMGEQEGQM--GEQEE--QMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK 245
Query: 334 KITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQ 393
+ +++++ ++KQ + E+E++ R+ + ++L K + E EE EQ +++R+
Sbjct: 246 QEEQVQKQEEQMRKQEEQMR-EQEEQMREQEEQMLKQKEQTEQEEQTGEQ----EEQMRE 300
Query: 394 KVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQ 453
+ + +++Q + Q E ++ +++ K E+ + E +
Sbjct: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE--------E 352
Query: 454 ELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKD 513
++ Q E +++Q + + ++ R E+M +++E+++KQ E++ Q Q + ++
Sbjct: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMRE 412
Query: 514 EEKAREALRQQKRK 527
+E+ ++Q RK
Sbjct: 413 QEEQMGEQKEQMRK 426
Score = 50.8 bits (120), Expect = 4e-06
Identities = 56/324 (17%), Positives = 144/324 (44%), Gaps = 75/324 (23%)
Query: 178 GQLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAA 237
GQ+ G+M + ++ + + ++ +Q EQ+ ++ E ++ + ++ EQ +Q
Sbjct: 185 GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQ 244
Query: 238 ERLREENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALG 297
+ +EE ++ ++ M ++
Sbjct: 245 K--QEEQVQKQEEQMRKQEEQ--------------------------------------- 263
Query: 298 AAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAE-R 356
++ + + +Q ++L+ +Q +Q ++ +Q E+++ E +++ + ++Q+ + E + R
Sbjct: 264 -MREQEEQMREQEEQMLKQKEQTEQEEQTGEQ--EEQMREQEEQMREQEEQMREQEEQMR 320
Query: 357 EQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEI 416
EQ+++ ++ + + K +M E KEQ+ + +++ ++ + +Q Q + +Q E K+
Sbjct: 321 EQEEQMGKQEEQMWEQKEQMWE-QKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQE 379
Query: 417 QRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRE 476
+++ K E+ +RKQE E + +Q + E ++
Sbjct: 380 EQMRKQEEQ------------------------MRKQE-----EQMGEQKEQMGEQKEQM 410
Query: 477 RSDRERMNEEKEELKKQVEKLQAQ 500
R E+M E+KE+++KQ E + Q
Sbjct: 411 REQEEQMGEQKEQMRKQEEHMGEQ 434
Score = 49.7 bits (117), Expect = 8e-06
Identities = 56/330 (16%), Positives = 144/330 (43%), Gaps = 29/330 (8%)
Query: 213 EQLRKENEALKAKLDKGLEQRDQAAERLRE--ENLELKKL-LMSNGNKEGASGRPGSPKM 269
E+L+++N L+ +L ++ + ++E LE K+ L G G+ +
Sbjct: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
Query: 270 EGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQ 329
+ ++ +Q+ V + G ++ + +Q ++ E Q + +++
Sbjct: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
Query: 330 QYEQKITELRQKLADLQKQVTDLEA---EREQKQRDFDRKLLLAKSKIEMEETDKEQLTA 386
Q E ++ E ++ + + QV + E E+E + R+ + ++ + ++ +E +
Sbjct: 127 Q-EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
Query: 387 EAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGA 446
+ +E ++ + Q+ Q QE+++Q+ + + E
Sbjct: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE------------------ 227
Query: 447 GALLRKQE--LVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLS 504
+RKQE + Q E +++Q + ++ ++ R E+M E++E++++Q E++ Q +
Sbjct: 228 --QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285
Query: 505 NAQLKAFKDEEKAREALRQQKRKAKASGER 534
+ + + EE+ RE Q + + + E+
Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQ 315
Score = 48.5 bits (114), Expect = 2e-05
Identities = 41/254 (16%), Positives = 118/254 (46%), Gaps = 16/254 (6%)
Query: 178 GQLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAA 237
GQ+ G+M + ++ + + +++ + EQ+RK+ E + + ++ +Q +Q
Sbjct: 192 GQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQ 251
Query: 238 E-----RLREENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPE 292
+ R +EE + ++ M ++ + + + E TG++ ++Q E
Sbjct: 252 KQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ---------E 302
Query: 293 VVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQK--ITELRQKLADLQKQVT 350
E+ + EQ R + ++ KQ +Q + +Q +EQK + + +++ + ++Q+
Sbjct: 303 EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQ 362
Query: 351 DLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQRE 410
E + +++ ++ + + E +EQ+ + +++ ++ + +++Q + Q+E
Sbjct: 363 KQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKE 422
Query: 411 YQEKEIQRLNKALE 424
K+ + + + E
Sbjct: 423 QMRKQEEHMGEQKE 436
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 67.8 bits (164), Expect = 3e-11
Identities = 87/395 (22%), Positives = 162/395 (41%), Gaps = 38/395 (9%)
Query: 165 ETTLSVCAEEPDHGQ---LFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEA 221
ETT S P Q L L ++ N+L + +Q+ ++ E+ +K N
Sbjct: 56 ETTTSGGGHSPGDSQYQELAVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNE 115
Query: 222 L-----------------KAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRP 264
+ KA L L +AA EE+ +L L + + R
Sbjct: 116 IHKAQMEQLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERA 175
Query: 265 GSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHF 324
S AV+ QQQ + E V ++ +K + + +V + Q
Sbjct: 176 LS---------AVSTQQQEEDRSSSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQ-V 225
Query: 325 RSMKQQYEQKITELRQKLAD-LQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQ 383
+ + +Y + I R + + + K + +E+K+RD R L +S E++ E
Sbjct: 226 QLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEP 285
Query: 384 LTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRL---NKALEEALSIQTPPSSPPTAF 440
+ + V+ LQD+ L ++ E E ++Q N+AL Q
Sbjct: 286 PSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEM 345
Query: 441 GSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQ 500
+ A + ++ L QNE L++Q K +E +R R +R+ +++E L+K+ E+LQ Q
Sbjct: 346 LREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQ 405
Query: 501 -VTLSNAQLKAFKDEEKAREALRQQKRKAKASGER 534
L + + + +K EE+ + +Q++R A + +
Sbjct: 406 EKRLWDQEERLWKKEERLQ---KQEERLALSQNHK 437
Score = 33.1 bits (74), Expect = 0.80
Identities = 18/48 (37%), Positives = 30/48 (62%), Gaps = 3/48 (6%)
Query: 26 ERLVKENSRLKEKMQGIKMLGELLEESQMEATRLRQKAEELVKDNELL 73
ERL ++N RL+E+ + ++ GE L + + RLR++ E L K+ E L
Sbjct: 358 ERLCEQNERLREQQKTLQEQGERLRKQEQ---RLRKQEERLRKEEERL 402
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 67.8 bits (164), Expect = 3e-11
Identities = 90/408 (22%), Positives = 171/408 (41%), Gaps = 43/408 (10%)
Query: 162 QRLETTLSVCAE-----EPDHGQLFTHLGRMALEFNRLASKVHKNEQRTSI--------L 208
++LE L + E E D QL L + E + L K+ ++EQ +I L
Sbjct: 1057 RKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKI-EDEQALAIQLQKKIKEL 1115
Query: 209 QTLCEQLRKENEALKAKLDKGLEQR-------DQAAERLREENLELKKLLMSNGNKEGAS 261
Q E+L +E EA +A K +QR ++ +ERL E + N +E
Sbjct: 1116 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEF 1175
Query: 262 GRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKM-LEQQRSEL-LEVN-- 317
+ E T + A V E+ + ++VK LE+++SEL +E+N
Sbjct: 1176 QKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDL 1235
Query: 318 -------KQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQ---KQRDFDRKL 367
+ +F M + E +++E++ K + Q+ + +L A++ + + +F R+L
Sbjct: 1236 ASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQL 1295
Query: 368 LLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEAL 427
+ + K+ T + +EL+++++ S L + + L + EE
Sbjct: 1296 DEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQ 1355
Query: 428 SIQ-------TPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDR 480
+ + +S + + A+ R +EL + L Q+++ EE + S
Sbjct: 1356 EAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKC 1415
Query: 481 ERMNEEKEELKKQVEKLQAQVTLSNAQLKAF-KDEEKAREALRQQKRK 527
+ + K+ L+ +VE L V SNA A K + + L + K+K
Sbjct: 1416 ASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQK 1463
Score = 58.9 bits (141), Expect = 1e-08
Identities = 86/396 (21%), Positives = 168/396 (42%), Gaps = 55/396 (13%)
Query: 150 LPREDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKV-HKNEQRTSIL 208
L E L L+ E +L E + G++ R+ LE N++ S++ K ++ L
Sbjct: 1537 LDHEKSELQTSLEEAEASL-----EHEEGKIL----RIQLELNQVKSEIDRKIAEKDEEL 1587
Query: 209 QTLCEQLRKENEALKAKLDKGLEQRDQAA--ERLREENLELKKLLMSNGNKEGASGRPGS 266
L + E++++ LD + R+ A ++ E +L ++ +++ N++ A
Sbjct: 1588 DQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNL 1647
Query: 267 PKMEGTGKK-------AVAGQ-----------QQASVTAGKVPEVVA------------- 295
+G K A+ GQ ++A++ +V E+ A
Sbjct: 1648 RNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAE 1707
Query: 296 --LGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLE 353
L A ++V++L Q + L+ K+ + ++ + E + E R +K +TD
Sbjct: 1708 QELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAA 1767
Query: 354 AEREQKQRDFDRKLLLAKSKIEMEETDKE-QL---TAEAKELRQKVKYLQDQLSPLTRQR 409
E+ +++ D L + K ME+T K+ QL AE L+ K +Q +L R+
Sbjct: 1768 MMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQ-KLEARVREL 1826
Query: 410 EYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELV----TQNELLKQQ 465
E + + Q+ N + L T + + E +LR Q+LV T+ + K+Q
Sbjct: 1827 ESEVESEQKHNVEAVKGLRKHERRVKELT-YQTEEDRKNILRLQDLVDKLQTKVKAYKRQ 1885
Query: 466 VKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQV 501
+ EE + ++ E EE K++ + ++QV
Sbjct: 1886 AEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQV 1921
Score = 58.5 bits (140), Expect = 2e-08
Identities = 72/342 (21%), Positives = 149/342 (43%), Gaps = 52/342 (15%)
Query: 190 EFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELKK 249
E N L +V + + C+QL K L+AK+ + E+ + E E + +K
Sbjct: 887 EKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRK 946
Query: 250 LLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVA-LGAAEKKVKMLEQ 308
L E + + +E T K +++ T KV + + ++ + L +
Sbjct: 947 L-----EDECSELKKDIDDLELTLAKV---EKEKHATENKVKNLTEEMAGLDETIAKLTK 998
Query: 309 QRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQR---DFDR 365
++ L E ++Q Q E K+ L + L++QV DLE EQ+++ D +R
Sbjct: 999 EKKALQEAHQQTLDDL----QMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLER 1054
Query: 366 KLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEE 425
AK K+E + ++ T + + +Q QL+ +++E++ +Q + E+
Sbjct: 1055 ----AKRKLEGDLKLAQESTMDTENDKQ-------QLNEKLKKKEFEMSNLQGKIED-EQ 1102
Query: 426 ALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNE 485
AL+IQ L + + L+ +++ EE+ + ER+ R + +
Sbjct: 1103 ALAIQ------------------------LQKKIKELQARIEELEEEIEAERASRAKAEK 1138
Query: 486 EKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRK 527
++ +L +++E++ ++ + A + K REA Q+ R+
Sbjct: 1139 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR 1180
Score = 49.7 bits (117), Expect = 8e-06
Identities = 89/408 (21%), Positives = 166/408 (40%), Gaps = 62/408 (15%)
Query: 156 NLMLHLQRLETTLSVCAEEPD-----HGQLFTHLGRMALEFNRLASKVHKNEQRTSILQT 210
NL + L+ T++ +E H Q L + N L K EQ+ L+
Sbjct: 981 NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEG 1040
Query: 211 LCEQLRK---ENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRPGSP 267
EQ +K + E K KL+ L+ ++ + +L + L
Sbjct: 1041 SLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKK------------- 1087
Query: 268 KMEGTGKKAVAGQQQASVTAGKVPEVVALGAA-EKKVKMLEQQRSELLEVNKQWDQHFRS 326
+ + S GK+ + AL +KK+K L Q R E LE + + R+
Sbjct: 1088 ------------EFEMSNLQGKIEDEQALAIQLQKKIKEL-QARIEELEEEIEAE---RA 1131
Query: 327 MKQQYEQKITELRQKLADLQKQVTDLE-AEREQKQRDFDRKLLLAKSKIEMEETDKEQLT 385
+ + E++ ++L ++L ++ +++ + A Q + + R+ K + ++EE+ +
Sbjct: 1132 SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQH-E 1190
Query: 386 AEAKELRQK----VKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFG 441
A A LR+K V L +Q+ L R ++ EKE L + + S S
Sbjct: 1191 ATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSK------ 1244
Query: 442 SPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSD----RERMNEEKEELKKQVEKL 497
A A K +++L ++K EE+ QR ++ + R++ E E +Q+++
Sbjct: 1245 ----AKANFEKMCRTLEDQL--SEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEK 1298
Query: 498 QAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASGERYHVEPHPEHLC 545
A V+ + +AF ++ E RQ + + KA H H C
Sbjct: 1299 DAMVSQLSRGKQAF--TQQIEELKRQLEEETKAKSTLAHALQSARHDC 1344
Score = 44.3 bits (103), Expect = 3e-04
Identities = 60/246 (24%), Positives = 109/246 (44%), Gaps = 30/246 (12%)
Query: 296 LGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAE 355
L +AE + +M + E E K+ + +++ E+K+ L Q+ DLQ QV +AE
Sbjct: 844 LKSAETEKEMANMK--EEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQV---QAE 898
Query: 356 REQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAK-------ELRQKVKYLQDQLSPLTRQ 408
+ +R L K+KI++E KE +T A+ EL K + L+D+ S L +
Sbjct: 899 ADALADAEERCDQLIKTKIQLEAKIKE-VTERAEDEEEINAELTAKKRKLEDECSELKKD 957
Query: 409 REYQEKEIQRLNK---ALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQ 465
+ E + ++ K A E + T E AG +L + + L++
Sbjct: 958 IDDLELTLAKVEKEKHATENKVKNLT-----------EEMAGLDETIAKLTKEKKALQEA 1006
Query: 466 VKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQK 525
+ +D Q E + + K +L++QV+ L+ + + K D E+A+ L
Sbjct: 1007 HQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSL---EQEKKLCMDLERAKRKLEGDL 1063
Query: 526 RKAKAS 531
+ A+ S
Sbjct: 1064 KLAQES 1069
Score = 43.5 bits (101), Expect = 6e-04
Identities = 91/419 (21%), Positives = 163/419 (38%), Gaps = 108/419 (25%)
Query: 187 MALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKG---LEQRDQAAERLREE 243
+ +E N LAS + + + + +C L + +K K ++ + + RL E
Sbjct: 1228 LKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTE 1287
Query: 244 NLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKV 303
+ E + L K+ + K T + +Q T K AL +A
Sbjct: 1288 SGEFSRQL---DEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDC 1344
Query: 304 KMLEQQRSELLEVNK--------------QWDQHFRSMKQQYEQKITELRQKLAD----- 344
+L +Q E E QW + + Q +++ E ++KLA
Sbjct: 1345 DLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDA 1404
Query: 345 --------------------LQKQVTDL--EAER--------EQKQRDFDRKLLLAKSKI 374
LQ +V DL + ER ++KQR+FD+ +LA+ K
Sbjct: 1405 EEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDK--VLAEWKQ 1462
Query: 375 EMEETDKEQLTAEAKE------------------------LRQKVKYLQDQLSPLTRQRE 410
+ EET E L A KE L+++ K LQ ++S LT Q
Sbjct: 1463 KYEETQAE-LEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIA 1521
Query: 411 YQEKEIQRLNKALE----EALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQV 466
K I L K + E +QT S E A A L +E ++L+ Q+
Sbjct: 1522 EGGKHIHELEKVKKQLDHEKSELQT----------SLEEAEASLEHEE----GKILRIQL 1567
Query: 467 KIFEEDFQRERSDRERMNEEKEELKKQ----VEKLQAQVTLSNAQLKAFKDEEKAREAL 521
++ + + +R E+ +EE ++LK+ VE +Q+ + +A++++ D + ++ +
Sbjct: 1568 ELNQVKSEIDRKIAEK-DEELDQLKRNHLRVVESMQSTL---DAEIRSRNDALRIKKKM 1622
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 67.4 bits (163), Expect = 4e-11
Identities = 96/428 (22%), Positives = 185/428 (43%), Gaps = 83/428 (19%)
Query: 156 NLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQL 215
+L+ + L+ L V DH + T L ++ +++ L T E+L
Sbjct: 501 SLLQEISSLQEKLEVT--RTDHQREITSLKE------HFGAREETHQKEIKALYTATEKL 552
Query: 216 RKENEALKAKLDKGLEQRD----------QAAERLREENLELKKLLMSNG----NKEGAS 261
KENE+LK+KL+ ++ + A ++ +E K+ S G E A
Sbjct: 553 SKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAE 612
Query: 262 GRPGSPKMEGTGKKAVAG--QQQASVTAGKVPEVVALGAAEKKVKMLEQQRSEL----LE 315
+ KM + + QQ S A E+ AL A K +K+++++ + L +
Sbjct: 613 LKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRA--KLMKVIKEKENSLEAIRSK 670
Query: 316 VNKQWDQHFRSMK------QQYEQKITELR-----------------QKLADLQKQVTDL 352
++K DQH M+ Q+ E K+ EL +L ++++ DL
Sbjct: 671 LDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDL 730
Query: 353 EA------EREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQ-------KVKYLQ 399
+A E + + + ++L A+ +I+ E +K +++A + + K+ LQ
Sbjct: 731 DALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQ 790
Query: 400 DQLSPLTRQREYQEKEIQRLN----KALEEALSIQTPPSSPPTAFGSPEGAGALLRKQE- 454
+ LS +++ +E EKE+Q L +A EEA+S+Q E L +K+E
Sbjct: 791 ENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQR---------SMQETVNKLHQKEEQ 841
Query: 455 ---LVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAF 511
L + E L++ + E F+ + E++ + KE+L+ + ++ +++QL
Sbjct: 842 FNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKM 901
Query: 512 KDEEKARE 519
DE + +E
Sbjct: 902 NDELRLKE 909
Score = 59.3 bits (142), Expect = 1e-08
Identities = 87/396 (21%), Positives = 165/396 (41%), Gaps = 67/396 (16%)
Query: 196 SKVHKNEQRTSILQTLCEQLRKENEALKAKL---DKGLEQRDQAAERLREENLELKKLLM 252
+K+H+ E++ ++L + E+LR+ ++AK D+ EQ +A E+L + E+ K+
Sbjct: 833 NKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSG 892
Query: 253 SNGN---KEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVV---------ALGAAE 300
N + K R +E K + AS + ++ A E
Sbjct: 893 DNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHE 952
Query: 301 KKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQK----LADLQKQVTDLE--- 353
++ K LE++ S+L + + + +K +YE+ +E + K L +LQK + D E
Sbjct: 953 EEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKL 1012
Query: 354 -------------AEREQKQRDFDRKLLLAKSKIEMEET---DKEQLTAEAKELRQKVKY 397
E +KQ D + A+ +++ E +K + A ++ +Q
Sbjct: 1013 KGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAK 1072
Query: 398 LQDQLSPLTRQREYQEKEIQRLNKALE----------------EALSIQTPPSSPPTAFG 441
LQ++L L +E K ++ LNK+ E E L S +
Sbjct: 1073 LQNELDTL---KENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL 1129
Query: 442 SPEG---AGALLRKQELVTQNELLKQQVKIFEEDF----QRERSDRERMNEEKEELKKQV 494
E A L R ++ VT ++ L+++ + +RE + +EEK L+K +
Sbjct: 1130 QEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSI 1189
Query: 495 EKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKA 530
A +T +A+L+ ++E LR + AK+
Sbjct: 1190 SITSALLTEKDAELEKLRNEV---TVLRGENASAKS 1222
Score = 53.1 bits (126), Expect = 7e-07
Identities = 66/336 (19%), Positives = 141/336 (41%), Gaps = 21/336 (6%)
Query: 197 KVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLRE--ENLELKKLLMSN 254
K+ ++ S + + E L KE + LK K + E+ ++E L K+ +
Sbjct: 785 KLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNM 844
Query: 255 GNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELL 314
+ + R ME ++ ++Q K+ +A + +KM S+L
Sbjct: 845 LSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIA-----EIMKMSGDNSSQLT 899
Query: 315 EVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKI 374
++N + R + ++ + K+T+ + + LQK + D+ + EQ Q++ +K
Sbjct: 900 KMNDELRLKERDV-EELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKK-------- 950
Query: 375 EMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPS 434
E +K++L + +L +K++ +Q L + E E + ++ + + L +
Sbjct: 951 --HEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDT 1008
Query: 435 SPPTAFGSPEGAGALLRKQELVTQNELLK--QQVKIFEEDFQRERSDRERMNEEKEELKK 492
E +G L +EL Q + K Q + + ++ ++ E+ K+
Sbjct: 1009 EDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQ 1068
Query: 493 QVEKLQAQV-TLSNAQLKAFKDEEKAREALRQQKRK 527
KLQ ++ TL LK ++ K++E L + +K
Sbjct: 1069 TNAKLQNELDTLKENNLKNVEELNKSKELLTVENQK 1104
Score = 41.6 bits (96), Expect = 0.002
Identities = 76/360 (21%), Positives = 148/360 (41%), Gaps = 53/360 (14%)
Query: 194 LASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERL-REENLELKKLLM 252
+AS V RT +L + ++ A L + L+++ Q E+L E +LE ++
Sbjct: 322 VASSVSSRPSRTGLLTETSSRYARKISGTTA-LQEALKEKQQHIEQLLAERDLERAEVAK 380
Query: 253 SNGN-----KEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLE 307
+ + +E A R G + +A Q + V A +V L E++ + +E
Sbjct: 381 ATSHVGEIEQELALARDGHDQ-HVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVE 439
Query: 308 QQRSELLEVN-KQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQR--DFD 364
+ + E + + D ++ ++ +I EL + LA ++V +L E + D D
Sbjct: 440 DLQFRVEEESITKGDLEVATVSEK--SRIMELEKDLALRVQEVAELRRRLESNKPAGDVD 497
Query: 365 RKLLLAKS------KIEMEETD--------KEQLTAEAKELRQKVKYLQDQLSPLTRQRE 410
L L + K+E+ TD KE A + ++++K L L+++ E
Sbjct: 498 MSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENE 557
Query: 411 YQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKI-F 469
+ +++ NK + +++ S TA S + A +++K+ F
Sbjct: 558 SLKSKLEHANKENSDVIALWK--SKLETAIASHQQA----------------MEELKVSF 599
Query: 470 EEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAK 529
+ E + E ELK Q+EK++ L+ +D E+A A + +AK
Sbjct: 600 SKGLGTETA-------EFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAK 652
Score = 38.1 bits (87), Expect = 0.025
Identities = 78/409 (19%), Positives = 160/409 (39%), Gaps = 64/409 (15%)
Query: 27 RLVKENSRLKEKMQGIKMLGELLEESQMEATR--------LRQKAEELVKDNELLPPPSP 78
+L K N + I+ + E+SQ EA + L +K +L K E
Sbjct: 918 KLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQ 977
Query: 79 SLGSFDPLA--ELTGKDSNVTASPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSP 136
L + A E K + + ++ + +SG E E + + +
Sbjct: 978 ELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAK 1037
Query: 137 ESSSHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLAS 196
+ + +AM + + ++ ET S+ + + +L L + +
Sbjct: 1038 AAQTAEDAMQIME--------QMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVE 1089
Query: 197 KVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGN 256
+++K+++ ++ E+ RKE E LK + Q+ Q L+EEN++L + L
Sbjct: 1090 ELNKSKELLTVENQKMEEFRKEIETLK----QAAAQKSQQLSALQEENVKLAEEL----- 1140
Query: 257 KEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEV 316
G + E T + + +++ SV ++ E ++++ S+ +
Sbjct: 1141 --------GRSRDEVTSHQKL--EEERSVLNNQLLE-------------MKKRESKFI-- 1175
Query: 317 NKQWDQHFRSMKQQYEQKITELRQKLADLQK---QVTDLEAEREQKQRDFDRKLLLAKSK 373
K D+ S+++ L +K A+L+K +VT L E + S
Sbjct: 1176 -KDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKS--------LHSV 1226
Query: 374 IEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKA 422
++ E+DK +L + K L ++K + QLS + + Q E +R ++
Sbjct: 1227 VQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQES 1275
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 67.4 bits (163), Expect = 4e-11
Identities = 96/428 (22%), Positives = 185/428 (43%), Gaps = 83/428 (19%)
Query: 156 NLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQL 215
+L+ + L+ L V DH + T L ++ +++ L T E+L
Sbjct: 536 SLLQEISSLQEKLEVT--RTDHQREITSLKE------HFGAREETHQKEIKALYTATEKL 587
Query: 216 RKENEALKAKLDKGLEQRD----------QAAERLREENLELKKLLMSNG----NKEGAS 261
KENE+LK+KL+ ++ + A ++ +E K+ S G E A
Sbjct: 588 SKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAE 647
Query: 262 GRPGSPKMEGTGKKAVAG--QQQASVTAGKVPEVVALGAAEKKVKMLEQQRSEL----LE 315
+ KM + + QQ S A E+ AL A K +K+++++ + L +
Sbjct: 648 LKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRA--KLMKVIKEKENSLEAIRSK 705
Query: 316 VNKQWDQHFRSMK------QQYEQKITELR-----------------QKLADLQKQVTDL 352
++K DQH M+ Q+ E K+ EL +L ++++ DL
Sbjct: 706 LDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDL 765
Query: 353 EA------EREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQ-------KVKYLQ 399
+A E + + + ++L A+ +I+ E +K +++A + + K+ LQ
Sbjct: 766 DALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQ 825
Query: 400 DQLSPLTRQREYQEKEIQRLN----KALEEALSIQTPPSSPPTAFGSPEGAGALLRKQE- 454
+ LS +++ +E EKE+Q L +A EEA+S+Q E L +K+E
Sbjct: 826 ENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQR---------SMQETVNKLHQKEEQ 876
Query: 455 ---LVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAF 511
L + E L++ + E F+ + E++ + KE+L+ + ++ +++QL
Sbjct: 877 FNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKM 936
Query: 512 KDEEKARE 519
DE + +E
Sbjct: 937 NDELRLKE 944
Score = 59.3 bits (142), Expect = 1e-08
Identities = 87/396 (21%), Positives = 165/396 (41%), Gaps = 67/396 (16%)
Query: 196 SKVHKNEQRTSILQTLCEQLRKENEALKAKL---DKGLEQRDQAAERLREENLELKKLLM 252
+K+H+ E++ ++L + E+LR+ ++AK D+ EQ +A E+L + E+ K+
Sbjct: 868 NKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSG 927
Query: 253 SNGN---KEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVV---------ALGAAE 300
N + K R +E K + AS + ++ A E
Sbjct: 928 DNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHE 987
Query: 301 KKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQK----LADLQKQVTDLE--- 353
++ K LE++ S+L + + + +K +YE+ +E + K L +LQK + D E
Sbjct: 988 EEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKL 1047
Query: 354 -------------AEREQKQRDFDRKLLLAKSKIEMEET---DKEQLTAEAKELRQKVKY 397
E +KQ D + A+ +++ E +K + A ++ +Q
Sbjct: 1048 KGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAK 1107
Query: 398 LQDQLSPLTRQREYQEKEIQRLNKALE----------------EALSIQTPPSSPPTAFG 441
LQ++L L +E K ++ LNK+ E E L S +
Sbjct: 1108 LQNELDTL---KENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL 1164
Query: 442 SPEG---AGALLRKQELVTQNELLKQQVKIFEEDF----QRERSDRERMNEEKEELKKQV 494
E A L R ++ VT ++ L+++ + +RE + +EEK L+K +
Sbjct: 1165 QEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSI 1224
Query: 495 EKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKA 530
A +T +A+L+ ++E LR + AK+
Sbjct: 1225 SITSALLTEKDAELEKLRNEV---TVLRGENASAKS 1257
Score = 53.1 bits (126), Expect = 7e-07
Identities = 66/336 (19%), Positives = 141/336 (41%), Gaps = 21/336 (6%)
Query: 197 KVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLRE--ENLELKKLLMSN 254
K+ ++ S + + E L KE + LK K + E+ ++E L K+ +
Sbjct: 820 KLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNM 879
Query: 255 GNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELL 314
+ + R ME ++ ++Q K+ +A + +KM S+L
Sbjct: 880 LSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIA-----EIMKMSGDNSSQLT 934
Query: 315 EVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKI 374
++N + R + ++ + K+T+ + + LQK + D+ + EQ Q++ +K
Sbjct: 935 KMNDELRLKERDV-EELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKK-------- 985
Query: 375 EMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPS 434
E +K++L + +L +K++ +Q L + E E + ++ + + L +
Sbjct: 986 --HEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDT 1043
Query: 435 SPPTAFGSPEGAGALLRKQELVTQNELLK--QQVKIFEEDFQRERSDRERMNEEKEELKK 492
E +G L +EL Q + K Q + + ++ ++ E+ K+
Sbjct: 1044 EDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQ 1103
Query: 493 QVEKLQAQV-TLSNAQLKAFKDEEKAREALRQQKRK 527
KLQ ++ TL LK ++ K++E L + +K
Sbjct: 1104 TNAKLQNELDTLKENNLKNVEELNKSKELLTVENQK 1139
Score = 39.7 bits (91), Expect = 0.009
Identities = 94/473 (19%), Positives = 186/473 (39%), Gaps = 73/473 (15%)
Query: 78 PSLGSFDPLAELT--GKDSNVTASPTAPACP---SDKPAPVQKPPSSGTSSEFEVVTPEE 132
P G F P+ ++T G S A A A + A +++ PS+ + S V
Sbjct: 267 PKYGLFAPVHKVTKIGFPSTTPAKAKANAVRRVMATTSASLKRSPSASSLSSMSSVASSV 326
Query: 133 QNSP-------ESSSHANAMALGPLPREDGNLMLHLQRLETTLSVC-AEEPDHGQLFTHL 184
+ P E+SS G ++ L Q +E L+ E + + +H+
Sbjct: 327 SSRPSRTGLLTETSSRYARKISGTTALQEA-LKEKQQHIEQLLAERDLERAEVAKATSHV 385
Query: 185 GRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREEN 244
G + E LA ++Q L+ +QLR EA + + L Q ++ ++ +
Sbjct: 386 GEIEQE---LALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQ 442
Query: 245 LELKKLLMSNGNKEGAS----GRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAE 300
+++ ++ G+ E + R + +K A + Q + +V V
Sbjct: 443 FRVEEESITKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATV------S 496
Query: 301 KKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAERE--Q 358
+K +++E ++ L V Q++ ELR++L + K D++ Q
Sbjct: 497 EKSRIMELEKDLALRV----------------QEVAELRRRL-ESNKPAGDVDMSLSLLQ 539
Query: 359 KQRDFDRKLLLAKSKIEMEETD-KEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQ 417
+ KL + ++ + E T KE A + ++++K L L+++ E + +++
Sbjct: 540 EISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLE 599
Query: 418 RLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKI-FEEDFQRE 476
NK + +++ S TA S + A +++K+ F + E
Sbjct: 600 HANKENSDVIALWK--SKLETAIASHQQA----------------MEELKVSFSKGLGTE 641
Query: 477 RSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAK 529
+ E ELK Q+EK++ L+ +D E+A A + +AK
Sbjct: 642 TA-------EFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAK 687
Score = 38.1 bits (87), Expect = 0.025
Identities = 78/409 (19%), Positives = 160/409 (39%), Gaps = 64/409 (15%)
Query: 27 RLVKENSRLKEKMQGIKMLGELLEESQMEATR--------LRQKAEELVKDNELLPPPSP 78
+L K N + I+ + E+SQ EA + L +K +L K E
Sbjct: 953 KLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQ 1012
Query: 79 SLGSFDPLA--ELTGKDSNVTASPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSP 136
L + A E K + + ++ + +SG E E + + +
Sbjct: 1013 ELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAK 1072
Query: 137 ESSSHANAMALGPLPREDGNLMLHLQRLETTLSVCAEEPDHGQLFTHLGRMALEFNRLAS 196
+ + +AM + + ++ ET S+ + + +L L + +
Sbjct: 1073 AAQTAEDAMQIME--------QMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVE 1124
Query: 197 KVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGN 256
+++K+++ ++ E+ RKE E LK + Q+ Q L+EEN++L + L
Sbjct: 1125 ELNKSKELLTVENQKMEEFRKEIETLK----QAAAQKSQQLSALQEENVKLAEEL----- 1175
Query: 257 KEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEV 316
G + E T + + +++ SV ++ E ++++ S+ +
Sbjct: 1176 --------GRSRDEVTSHQKL--EEERSVLNNQLLE-------------MKKRESKFI-- 1210
Query: 317 NKQWDQHFRSMKQQYEQKITELRQKLADLQK---QVTDLEAEREQKQRDFDRKLLLAKSK 373
K D+ S+++ L +K A+L+K +VT L E + S
Sbjct: 1211 -KDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKS--------LHSV 1261
Query: 374 IEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKA 422
++ E+DK +L + K L ++K + QLS + + Q E +R ++
Sbjct: 1262 VQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQES 1310
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 67.0 bits (162), Expect = 5e-11
Identities = 102/439 (23%), Positives = 171/439 (38%), Gaps = 83/439 (18%)
Query: 165 ETTLSVCAEEPDHGQLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEAL-- 222
ETT S P+ T R L+ + AS H+ E LR+E EA
Sbjct: 59 ETTTSGGCHSPED----TQQNRAQLKEEKKASHQHQ------------EALRREIEAQDH 102
Query: 223 --------KAKLDKGLEQRDQAAERLREENLELKK---LLMSNGNKEGASGRPGSPKMEG 271
K +L+ L AA + + NL L +S + G + + G
Sbjct: 103 TIRILTCQKTELETALYYSQDAARKFEDGNLGTPSSFNLALSQAFRGSPLGCVSTSLIPG 162
Query: 272 TGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQY 331
K + AG++ AL A + K ++ EL + + + Y
Sbjct: 163 ESKDLAGRLHHSWHFAGELQR--ALSAVSTRHKKADRYIEELTK------ERDALSLELY 214
Query: 332 EQKIT--ELRQKLADLQKQVTDLEAEREQKQ---RDFDRKLLLAKSKIEMEETD--KEQL 384
IT EL++K A+LQ+++ E+E+ + Q ++ RKL AK + +T+ +E++
Sbjct: 215 RNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEM 274
Query: 385 TAEAKELRQKVKYLQDQLSPLTRQREY------------------------QEKEIQRLN 420
+ +ELR++ K ++ Q + RQ E QEKE++
Sbjct: 275 WRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQE 334
Query: 421 KALEEALSIQTPPSSPPTAFGSPEGAGALLRKQE--LVTQNELLKQQVKIFEEDFQRERS 478
K L E ++ +R+QE + Q E L +Q K E Q+ R
Sbjct: 335 KELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 394
Query: 479 DRERMNEEKEELK-------------KQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQK 525
ERM E+ E L+ +QVEK++ + + + K EEK +E R ++
Sbjct: 395 QEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRE 454
Query: 526 RKAKASGERYHVEPHPEHL 544
R+ K E + E +
Sbjct: 455 REKKMREEEETMREQEEKM 473
Score = 65.9 bits (159), Expect = 1e-10
Identities = 72/350 (20%), Positives = 166/350 (47%), Gaps = 40/350 (11%)
Query: 197 KVHKNEQRTSILQTLCEQLRKENEALKA----KLDKGLEQRDQAAERLREENLELKKLLM 252
++ + E+R + + EQ+ K E K K + E++ Q ER+RE ++++
Sbjct: 405 RLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMRE--- 461
Query: 253 SNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSE 312
E + R KM+ +Q+ ++ + E E+K K+ EQ++ +
Sbjct: 462 -----EEETMREQEEKMQ---------KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 507
Query: 313 LLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKS 372
E K W+Q ++ Q E E + + ++ D E+E+K RD ++K+ +
Sbjct: 508 EQE-EKIWEQE-EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 565
Query: 373 KIEMEETDKEQLT-------AEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEE 425
++E + ++E+ T E + +R++ K ++++ + Q E +++ +++ + E+
Sbjct: 566 RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEK 625
Query: 426 ALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNE 485
+ E +++++ Q L +Q+ K++E + +E +E+M E
Sbjct: 626 MWEQEEKMQEQEEKMWEQE-EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE---QEKMQE 681
Query: 486 EKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAR--EALRQQKRKAKASGE 533
++E++ +Q EK++ + + Q K D+EK R E++R++++K + E
Sbjct: 682 QEEKIWEQ-EKMEKK---TQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Score = 63.2 bits (152), Expect = 7e-10
Identities = 58/242 (23%), Positives = 118/242 (48%), Gaps = 18/242 (7%)
Query: 300 EKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQK 359
E++ +M EQ+ + K WDQ +++ E+K E +K D ++++ + E RE++
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQ-----EERMEKKTQEQEKKTWDQEEKMREEERMRERE 595
Query: 360 QRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQR----EYQEK- 414
++ + + ++ + + +M+E +++ E K Q+ K +Q+Q + Q E +EK
Sbjct: 596 KKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEK-MQEQEEKMWEQEEKMWEQEEKM 654
Query: 415 -EIQRLNKALE-----EALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKI 468
E QRL + E E + Q E ++QE T ++ ++ +
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES 714
Query: 469 FEEDFQRERSDRERMNEEKEELKKQVEKLQAQ-VTLSNAQLKAFKDEEKAREALRQQKRK 527
E ++ R + E M E++E++++Q EK+Q Q + + K ++ EEK E R ++K
Sbjct: 715 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQK 774
Query: 528 AK 529
K
Sbjct: 775 EK 776
Score = 60.8 bits (146), Expect = 4e-09
Identities = 78/381 (20%), Positives = 162/381 (42%), Gaps = 45/381 (11%)
Query: 166 TTLSVCAEEPDHGQLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAK 225
+T + E D H A E R S V ++ E+L KE +AL +
Sbjct: 156 STSLIPGESKDLAGRLHHSWHFAGELQRALSAVSTRHKKAD---RYIEELTKERDALSLE 212
Query: 226 LDKGLEQRDQAAERLREENLELK-KLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQAS 284
L + E L+++N EL+ KL ++ K K + K + Q Q +
Sbjct: 213 LYRNTITN----EELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTN 268
Query: 285 VTAGKV-PEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLA 343
++ + L EKK++ E+ K W Q R +Q E K+ E +K+
Sbjct: 269 TLQEEMWRQEEELREQEKKIRKQEE---------KMWRQEERLREQ--EGKMREQEEKMW 317
Query: 344 DLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLS 403
+K++ + E E +++++ + L + + +M+E +++ E K Q+ K + +
Sbjct: 318 RQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 377
Query: 404 PLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLK 463
++++ +E+E + ++ EE + Q L K+E + + E +
Sbjct: 378 LWEQEKQMREQEQKMRDQ--EERMWEQDE---------------RLREKEERMREQEKMW 420
Query: 464 QQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQ 523
+QV+ E+ ++M E++++ + Q EK+Q + + + K ++EE RE +
Sbjct: 421 EQVEKMREE--------KKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK 472
Query: 524 QKRKAKASGERYHVEPHPEHL 544
+++ + E+ E + L
Sbjct: 473 MQKQEENMWEQEEKEWQQQRL 493
Score = 58.5 bits (140), Expect = 2e-08
Identities = 76/369 (20%), Positives = 165/369 (44%), Gaps = 56/369 (15%)
Query: 210 TLCEQLRKENEALKA---KLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRPGS 266
TL E++ ++ E L+ K+ K E+ + ERLRE+ ++++ +E R
Sbjct: 269 TLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMRE-------QEEKMWRQEK 321
Query: 267 PKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRS 326
E ++ +Q+ + K E++ KM EQ+ + K W Q R
Sbjct: 322 RLRE---QEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 378
Query: 327 MKQQYEQKITELRQKLADLQKQVTDLEA---EREQKQRDFDR------KLLLAKSKIEME 377
+Q E+++ E QK+ D ++++ + + E+E++ R+ ++ K+ K E E
Sbjct: 379 WEQ--EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQE 436
Query: 378 ET--DKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSS 435
+ D+E+ E + +R++ K ++++ + Q E +K+ + + + E+ Q P
Sbjct: 437 KKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 496
Query: 436 PPTAFGSP---EGAGALLRKQELVT-QNELLKQQVKIFEEDFQRERSDR----------- 480
+ E + ++E + Q E+ Q+ K++ ++ RE+ D+
Sbjct: 497 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 556
Query: 481 --------ERMNEEKEELKK----QVEKLQAQVTLSNAQLKAFKDEEKAR---EALRQQK 525
ERM ++ +E +K Q EK++ + + + K ++EE R E +++Q+
Sbjct: 557 EQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 616
Query: 526 RKAKASGER 534
K + E+
Sbjct: 617 EKMQEQEEK 625
Score = 55.8 bits (133), Expect = 1e-07
Identities = 74/361 (20%), Positives = 162/361 (44%), Gaps = 41/361 (11%)
Query: 193 RLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLM 252
R+ K + E++T E+ +E E ++ + K E+ + E+ EE ++ ++ M
Sbjct: 566 RMEKKTQEQEKKTWDQ----EEKMREEERMREREKKMREEEEMMREQ--EEKMQEQEEKM 619
Query: 253 SNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKV----KMLEQ 308
++ KM+ +K +++ K+ E L ++K+ KM EQ
Sbjct: 620 QEQEEKMWEQEE---KMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ 676
Query: 309 QRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLL 368
++ + E K W+Q K Q ++K T ++K+ + + ERE+K R+ + +
Sbjct: 677 EKMQEQE-EKIWEQEKMEKKTQEQEKKTWDQEKMREEESM-----REREKKMREEEEMMR 730
Query: 369 LAKSKIE-----MEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKAL 423
+ K++ M+E ++E E K Q+ K + Q P +++ ++ +++Q K
Sbjct: 731 EQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIW 790
Query: 424 EEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERM 483
E+ ++ G +R QE ++ Q+ K++ ++ ++ E+M
Sbjct: 791 EQEEKMRDQEE-------KMRGQEEKMRGQE----EKMRGQEEKMWGQE-EKMWGQEEKM 838
Query: 484 NEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAR---EALRQQKRKAKASGERYHVEPH 540
++E++ Q EK++ + + + K + EEK R E +R+Q+ K + E+ +
Sbjct: 839 WGQEEKMWGQEEKMEEK--MQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIYCVGS 896
Query: 541 P 541
P
Sbjct: 897 P 897
>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
sapiens]
Length = 638
Score = 67.0 bits (162), Expect = 5e-11
Identities = 78/366 (21%), Positives = 145/366 (39%), Gaps = 73/366 (19%)
Query: 180 LFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAER 239
L T L +M N + + L+ +L + NE LK+K + Q++
Sbjct: 22 LETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKN----- 76
Query: 240 LREENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAA 299
LR +LEL KL NK R K EG K Q+ + GK+ ++ +
Sbjct: 77 LRILSLELMKLR----NKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVS 132
Query: 300 EKKVKMLEQQRSELL-------------------------EVNKQWDQHFRSMKQQYEQK 334
+K K+ E+ +E L E K+ + S+KQ E+
Sbjct: 133 IEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEEN 192
Query: 335 ITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQK 394
I L +++ DL + LE E+E + E L AE + L+QK
Sbjct: 193 IVILSKQVEDLNVKCQLLEKEKE--------------DHVNRNREHNENLNAEMQNLKQK 238
Query: 395 VKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQE 454
L+ Q +Q+E Q + + K L +L Q+
Sbjct: 239 F-ILEQQEREKLQQKELQIDSLLQQEKELSSSL------------------------HQK 273
Query: 455 LVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDE 514
L + E + ++ +FEE+ ++ + +++ +++E+ ++ V++L+ + +LK +++
Sbjct: 274 LCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEK 333
Query: 515 EKAREA 520
K +EA
Sbjct: 334 LKGKEA 339
Score = 48.1 bits (113), Expect = 2e-05
Identities = 87/379 (22%), Positives = 160/379 (42%), Gaps = 49/379 (12%)
Query: 200 KNEQRTSILQTLC----EQLRKEN---EALKAKLDK--GLEQRDQAAERL---------- 240
+ E +S+ Q LC E ++++N E LK LD+ L+Q+++ AERL
Sbjct: 263 EKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKS 322
Query: 241 REENLEL--KKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGA 298
R E L+L +KL E +S + K Q VTA + AL A
Sbjct: 323 RAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTA-QFESYKALTA 381
Query: 299 AEKKVKMLE----QQRSELLEVNKQWDQH----FRSMKQQYEQ-----------KITELR 339
+E + LE Q+++ N + QH S Q+Y + K TE++
Sbjct: 382 SEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIK 441
Query: 340 QKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQ 399
+ +++TDL+ + +Q++ DF ++L + + +E +LT E + R + L
Sbjct: 442 EITVSFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELY 501
Query: 400 DQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQN 459
++ P Q + E E Q L L E + Q + ++ G L +K + V +
Sbjct: 502 NKTKPFQLQLDAFEVEKQAL---LNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVK- 557
Query: 460 ELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKARE 519
LK + + + + R + + + +L++++ K+ + KAF E K
Sbjct: 558 --LKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPS--KAFHHESKENF 613
Query: 520 ALRQQKRKAKASGERYHVE 538
AL+ ++ + R +E
Sbjct: 614 ALKTPLKEGNTNCYRAPME 632
Score = 40.8 bits (94), Expect = 0.004
Identities = 51/229 (22%), Positives = 101/229 (44%), Gaps = 31/229 (13%)
Query: 301 KKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQ 360
K+ +LEQQ E L+ Q + S+ QQ ++ + L QKL Q+++ +++
Sbjct: 236 KQKFILEQQEREKLQ---QKELQIDSLLQQEKELSSSLHQKLCSFQEEMV-------KEK 285
Query: 361 RDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLN 420
F+ +L +++ + +EQ K+L ++ K ++L L + + +E E+++ +
Sbjct: 286 NLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSS 345
Query: 421 KALEEA-LSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSD 479
A +A L +Q S S E A + +T +E+ ED + E S
Sbjct: 346 AAHTQATLLLQEKYDS---MVQSLEDVTAQFESYKALTASEI---------EDLKLENSS 393
Query: 480 RERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKA 528
+ E+ + K E +Q Q+ + + ++E R L Q + A
Sbjct: 394 ---LQEKAAKAGKNAEDVQHQILATES-----SNQEYVRMLLDLQTKSA 434
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 67.0 bits (162), Expect = 5e-11
Identities = 78/366 (21%), Positives = 145/366 (39%), Gaps = 73/366 (19%)
Query: 180 LFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAER 239
L T L +M N + + L+ +L + NE LK+K + Q++
Sbjct: 109 LETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKN----- 163
Query: 240 LREENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAA 299
LR +LEL KL NK R K EG K Q+ + GK+ ++ +
Sbjct: 164 LRILSLELMKLR----NKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVS 219
Query: 300 EKKVKMLEQQRSELL-------------------------EVNKQWDQHFRSMKQQYEQK 334
+K K+ E+ +E L E K+ + S+KQ E+
Sbjct: 220 IEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEEN 279
Query: 335 ITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQK 394
I L +++ DL + LE E+E + E L AE + L+QK
Sbjct: 280 IVILSKQVEDLNVKCQLLEKEKE--------------DHVNRNREHNENLNAEMQNLKQK 325
Query: 395 VKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQE 454
L+ Q +Q+E Q + + K L +L Q+
Sbjct: 326 F-ILEQQEREKLQQKELQIDSLLQQEKELSSSL------------------------HQK 360
Query: 455 LVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDE 514
L + E + ++ +FEE+ ++ + +++ +++E+ ++ V++L+ + +LK +++
Sbjct: 361 LCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEK 420
Query: 515 EKAREA 520
K +EA
Sbjct: 421 LKGKEA 426
Score = 48.1 bits (113), Expect = 2e-05
Identities = 87/379 (22%), Positives = 160/379 (42%), Gaps = 49/379 (12%)
Query: 200 KNEQRTSILQTLC----EQLRKEN---EALKAKLDK--GLEQRDQAAERL---------- 240
+ E +S+ Q LC E ++++N E LK LD+ L+Q+++ AERL
Sbjct: 350 EKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKS 409
Query: 241 REENLEL--KKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGA 298
R E L+L +KL E +S + K Q VTA + AL A
Sbjct: 410 RAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTA-QFESYKALTA 468
Query: 299 AEKKVKMLE----QQRSELLEVNKQWDQH----FRSMKQQYEQ-----------KITELR 339
+E + LE Q+++ N + QH S Q+Y + K TE++
Sbjct: 469 SEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIK 528
Query: 340 QKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQ 399
+ +++TDL+ + +Q++ DF ++L + + +E +LT E + R + L
Sbjct: 529 EITVSFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELY 588
Query: 400 DQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQN 459
++ P Q + E E Q L L E + Q + ++ G L +K + V +
Sbjct: 589 NKTKPFQLQLDAFEVEKQAL---LNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVK- 644
Query: 460 ELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKARE 519
LK + + + + R + + + +L++++ K+ + KAF E K
Sbjct: 645 --LKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPS--KAFHHESKENF 700
Query: 520 ALRQQKRKAKASGERYHVE 538
AL+ ++ + R +E
Sbjct: 701 ALKTPLKEGNTNCYRAPME 719
Score = 40.8 bits (94), Expect = 0.004
Identities = 51/229 (22%), Positives = 101/229 (44%), Gaps = 31/229 (13%)
Query: 301 KKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQ 360
K+ +LEQQ E L+ Q + S+ QQ ++ + L QKL Q+++ +++
Sbjct: 323 KQKFILEQQEREKLQ---QKELQIDSLLQQEKELSSSLHQKLCSFQEEMV-------KEK 372
Query: 361 RDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLN 420
F+ +L +++ + +EQ K+L ++ K ++L L + + +E E+++ +
Sbjct: 373 NLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSS 432
Query: 421 KALEEA-LSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSD 479
A +A L +Q S S E A + +T +E+ ED + E S
Sbjct: 433 AAHTQATLLLQEKYDS---MVQSLEDVTAQFESYKALTASEI---------EDLKLENSS 480
Query: 480 RERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKA 528
+ E+ + K E +Q Q+ + + ++E R L Q + A
Sbjct: 481 ---LQEKAAKAGKNAEDVQHQILATES-----SNQEYVRMLLDLQTKSA 521
>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
sapiens]
Length = 709
Score = 67.0 bits (162), Expect = 5e-11
Identities = 78/366 (21%), Positives = 145/366 (39%), Gaps = 73/366 (19%)
Query: 180 LFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAER 239
L T L +M N + + L+ +L + NE LK+K + Q++
Sbjct: 93 LETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKN----- 147
Query: 240 LREENLELKKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGAA 299
LR +LEL KL NK R K EG K Q+ + GK+ ++ +
Sbjct: 148 LRILSLELMKLR----NKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVS 203
Query: 300 EKKVKMLEQQRSELL-------------------------EVNKQWDQHFRSMKQQYEQK 334
+K K+ E+ +E L E K+ + S+KQ E+
Sbjct: 204 IEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEEN 263
Query: 335 ITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQK 394
I L +++ DL + LE E+E + E L AE + L+QK
Sbjct: 264 IVILSKQVEDLNVKCQLLEKEKE--------------DHVNRNREHNENLNAEMQNLKQK 309
Query: 395 VKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQE 454
L+ Q +Q+E Q + + K L +L Q+
Sbjct: 310 F-ILEQQEREKLQQKELQIDSLLQQEKELSSSL------------------------HQK 344
Query: 455 LVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDE 514
L + E + ++ +FEE+ ++ + +++ +++E+ ++ V++L+ + +LK +++
Sbjct: 345 LCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEK 404
Query: 515 EKAREA 520
K +EA
Sbjct: 405 LKGKEA 410
Score = 48.1 bits (113), Expect = 2e-05
Identities = 87/379 (22%), Positives = 160/379 (42%), Gaps = 49/379 (12%)
Query: 200 KNEQRTSILQTLC----EQLRKEN---EALKAKLDK--GLEQRDQAAERL---------- 240
+ E +S+ Q LC E ++++N E LK LD+ L+Q+++ AERL
Sbjct: 334 EKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKS 393
Query: 241 REENLEL--KKLLMSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGA 298
R E L+L +KL E +S + K Q VTA + AL A
Sbjct: 394 RAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTA-QFESYKALTA 452
Query: 299 AEKKVKMLE----QQRSELLEVNKQWDQH----FRSMKQQYEQ-----------KITELR 339
+E + LE Q+++ N + QH S Q+Y + K TE++
Sbjct: 453 SEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIK 512
Query: 340 QKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQ 399
+ +++TDL+ + +Q++ DF ++L + + +E +LT E + R + L
Sbjct: 513 EITVSFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELY 572
Query: 400 DQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQN 459
++ P Q + E E Q L L E + Q + ++ G L +K + V +
Sbjct: 573 NKTKPFQLQLDAFEVEKQAL---LNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVK- 628
Query: 460 ELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKARE 519
LK + + + + R + + + +L++++ K+ + KAF E K
Sbjct: 629 --LKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPS--KAFHHESKENF 684
Query: 520 ALRQQKRKAKASGERYHVE 538
AL+ ++ + R +E
Sbjct: 685 ALKTPLKEGNTNCYRAPME 703
Score = 40.8 bits (94), Expect = 0.004
Identities = 51/229 (22%), Positives = 101/229 (44%), Gaps = 31/229 (13%)
Query: 301 KKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQ 360
K+ +LEQQ E L+ Q + S+ QQ ++ + L QKL Q+++ +++
Sbjct: 307 KQKFILEQQEREKLQ---QKELQIDSLLQQEKELSSSLHQKLCSFQEEMV-------KEK 356
Query: 361 RDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLN 420
F+ +L +++ + +EQ K+L ++ K ++L L + + +E E+++ +
Sbjct: 357 NLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSS 416
Query: 421 KALEEA-LSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEEDFQRERSD 479
A +A L +Q S S E A + +T +E+ ED + E S
Sbjct: 417 AAHTQATLLLQEKYDS---MVQSLEDVTAQFESYKALTASEI---------EDLKLENSS 464
Query: 480 RERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKA 528
+ E+ + K E +Q Q+ + + ++E R L Q + A
Sbjct: 465 ---LQEKAAKAGKNAEDVQHQILATES-----SNQEYVRMLLDLQTKSA 505
Score = 37.7 bits (86), Expect = 0.033
Identities = 59/295 (20%), Positives = 118/295 (40%), Gaps = 43/295 (14%)
Query: 280 QQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYE------- 332
QQ+ S V + L A+ +KVK E + LL+ D+ + ++ + E
Sbjct: 46 QQKESKQNLNVDKDTTLPASARKVKSSESKIRVLLQERGAQDRRIQDLETELEKMEARLN 105
Query: 333 ---QKITELRQKLADLQKQVTDLEAEREQKQRDFDR------------KLLLAKSKIEME 377
++ T L A L+KQ+ +L E + F +L+ ++K E +
Sbjct: 106 AALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETK 165
Query: 378 ETD----------KEQLTAEAKELRQ-KVKYLQDQLSPLTRQREYQEKEIQRLNKALEEA 426
K Q+T + E Q K+ L+ +L + +++ ++ E ++L + +EE
Sbjct: 166 MRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEI 225
Query: 427 LSIQTPPSSPPTAFGSPE------GAGALLRKQELVTQNELLKQQVKIFE---EDFQRER 477
E L KQ L +L +QV+ + ++E+
Sbjct: 226 SCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEK 285
Query: 478 SDR-ERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKAS 531
D R E E L +++ L+ + L + + + +E ++L QQ+++ +S
Sbjct: 286 EDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSS 340
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,336,673
Number of Sequences: 37866
Number of extensions: 1591931
Number of successful extensions: 22914
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 482
Number of HSP's successfully gapped in prelim test: 1332
Number of HSP's that attempted gapping in prelim test: 11119
Number of HSP's gapped (non-prelim): 7546
length of query: 636
length of database: 18,247,518
effective HSP length: 109
effective length of query: 527
effective length of database: 14,120,124
effective search space: 7441305348
effective search space used: 7441305348
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.