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Search of human proteins with 239741055
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
(426 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo ... 870 0.0
gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo ... 865 0.0
gi|194018546 PRAME family member 10 [Homo sapiens] 827 0.0
gi|157426839 PRAME family member 17 [Homo sapiens] 739 0.0
gi|113865933 PRAME family member 16 [Homo sapiens] 737 0.0
gi|154800493 PRAME family member 22 [Homo sapiens] 542 e-154
gi|153791443 PRAME family member 18 [Homo sapiens] 537 e-153
gi|194306638 PRAME family member 3 [Homo sapiens] 536 e-152
gi|194306635 PRAME family member 19 [Homo sapiens] 534 e-152
gi|153792140 PRAME family member 14 [Homo sapiens] 526 e-149
gi|12738831 PRAME family member 1 [Homo sapiens] 513 e-145
gi|66954681 PRAME family member 13 [Homo sapiens] 506 e-143
gi|12738834 PRAME family member 2 [Homo sapiens] 491 e-139
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens] 471 e-133
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 420 e-117
gi|59676587 PRAME family member 8 [Homo sapiens] 420 e-117
gi|124249372 PRAME family member 12 [Homo sapiens] 419 e-117
gi|59676593 PRAME family member 7 [Homo sapiens] 417 e-117
gi|153792112 PRAME family member 20 [Homo sapiens] 396 e-110
gi|153945800 PRAME family member 21 [Homo sapiens] 396 e-110
gi|148356236 PRAME family member 15 [Homo sapiens] 381 e-106
gi|61102721 PRAME family member 9 [Homo sapiens] 381 e-106
gi|61696142 PRAME family member 5 [Homo sapiens] 379 e-105
gi|58219004 PRAME family member 6 [Homo sapiens] 379 e-105
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 378 e-105
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens] 374 e-104
gi|59958373 PRAME family member 4 [Homo sapiens] 372 e-103
gi|226437621 PRAME family member 11 [Homo sapiens] 328 7e-90
gi|46249373 preferentially expressed antigen in melanoma [Homo s... 325 6e-89
gi|46249371 preferentially expressed antigen in melanoma [Homo s... 325 6e-89
>gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 870 bits (2247), Expect = 0.0
Identities = 426/426 (100%), Positives = 426/426 (100%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 RYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVA 300
RYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVA
Sbjct: 241 RYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVA 300
Query: 301 ATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLG 360
ATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLG
Sbjct: 301 ATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLG 360
Query: 361 LELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKV 420
LELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKV
Sbjct: 361 LELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKV 420
Query: 421 DFHLCS 426
DFHLCS
Sbjct: 421 DFHLCS 426
>gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 865 bits (2236), Expect = 0.0
Identities = 424/426 (99%), Positives = 425/426 (99%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 RYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVA 300
RYLKNPLGAFIFSDAYL DRDMECLSQYPSLSQLKELRLIHILMWTT+LEPLGVLLEKVA
Sbjct: 241 RYLKNPLGAFIFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTNLEPLGVLLEKVA 300
Query: 301 ATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLG 360
ATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLG
Sbjct: 301 ATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLG 360
Query: 361 LELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKV 420
LELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKV
Sbjct: 361 LELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKV 420
Query: 421 DFHLCS 426
DFHLCS
Sbjct: 421 DFHLCS 426
>gi|194018546 PRAME family member 10 [Homo sapiens]
Length = 474
Score = 827 bits (2137), Expect = 0.0
Identities = 418/474 (88%), Positives = 418/474 (88%), Gaps = 48/474 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
FL LPLGSLMKT HLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR
Sbjct: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
VLSCSPEAMSKRQTVEDCPRMGE QPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELF
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
Query: 241 ------------------------------------------------RYLKNPLGAFIF 252
RYLKNPLGAFIF
Sbjct: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
Query: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
SDAYL DRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR
Sbjct: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
Query: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHT GLSKLGLELYPAPLESLD
Sbjct: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
Query: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS 426
YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCP CGSWPSEKVDFHLCS
Sbjct: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLCS 474
>gi|157426839 PRAME family member 17 [Homo sapiens]
Length = 474
Score = 739 bits (1907), Expect = 0.0
Identities = 376/474 (79%), Positives = 393/474 (82%), Gaps = 48/474 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQ+PSRLLELAGQSLLRNQFLTIF LDELPREVFPLMFMEA SMR FEALKLMVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
FLRLPLGSLMKTPHLETLQAVL+GLDTL+AQK+RPRRWKLQVLDLRDVD NFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSCSPEAMSKRQTVED PR GE QPLKVFIDLC KESTLDECLSYL WIHYRRGLVHL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
CC+KVQNYSMPTSSFRNLL+R+YPDSIQELE+ +KCSLNKTGKFAPYLSQMSNLR+LF
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 ------------------------------------------------RYLKNPLGAFIF 252
R LKNPLG FIF
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
Query: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
AYLAD+DMECLSQYPSLSQLKEL LIHILMWTT+LEPLG LLEKVAATL+ L LKDC+
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
Query: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
IQD QLRVLLPALS CSQLTTF F GNETS NALKDLL HT GLSKLGLELYPAPLE LD
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
Query: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS 426
+GHVNWEIL PIRAELM TLREVRQPKRIFFGP+PCP+CGSWPSEKVDFHLCS
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474
>gi|113865933 PRAME family member 16 [Homo sapiens]
Length = 474
Score = 737 bits (1902), Expect = 0.0
Identities = 375/474 (79%), Positives = 392/474 (82%), Gaps = 48/474 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQ+PSRLLELAGQSLLRNQFLTIF LDELPREVFPLMFMEA SMR FEALKLMVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
FLRLPLGSLMKTPHLETLQAVL+GLDTL+AQK+RPRRWKLQVLDLRDVD NFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSCSPEAM KRQTVED PR GE QPLKVFIDLC KESTLDECLSYL WIHYRRGLVHL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
CC+KVQNYSMPTSSFRNLL+R+YPDSIQELE+ +KCSLNKTGKFAPYLSQMSNLR+LF
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 ------------------------------------------------RYLKNPLGAFIF 252
R LKNPLG FIF
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
Query: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
AYLAD+DMECLSQYPSLSQLKEL LIHILMWTT+LEPLG LLEKVAATL+ L LKDC+
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
Query: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
IQD QLRVLLPALS CSQLTTF F GNETS NALKDLL HT GLSKLGLELYPAPLE LD
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
Query: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS 426
+GHVNWEIL PIRAELM TLREVRQPKRIFFGP+PCP+CGSWPSEKVDFHLCS
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474
>gi|154800493 PRAME family member 22 [Homo sapiens]
Length = 481
Score = 542 bits (1396), Expect = e-154
Identities = 284/473 (60%), Positives = 335/473 (70%), Gaps = 48/473 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQAP RLLELAGQSLL +Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D L+AQKVRPRRWKLQVL+LRDVDENFWTIWSGAR
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSCSPEAMSKRQTVEDCPR GE+QPLKVF+D+CLKE +DE LS+ GW+ +RRG VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C +F+ YLSQM NLR+LF
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
Query: 241 ------------------------------------------------RYLKNPLGAFIF 252
R L++PL
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Query: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
+ +L D++CL +YPSLSQLK+L L H + LEPL LLEKVAATL+TL L DC
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
Query: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
I+D +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHT LS L LE YPAP ESLD
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
Query: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425
+G V E+LTP++AELMR LREVR+PKRIFFGPV CP CG+ P+E+++F+ C
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
>gi|153791443 PRAME family member 18 [Homo sapiens]
Length = 479
Score = 537 bits (1384), Expect = e-153
Identities = 281/473 (59%), Positives = 330/473 (69%), Gaps = 48/473 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS QAP RLLELAGQSLLR+Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D L+AQKVRPRRWKLQVL++RDVDENFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSCSPEAMSKRQTVEDCPR GE+QPLKVF+D+CLKE ++DE LS+ GW+ +RR VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C + + YLSQM NLR+LF
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 ------------------------------------------------RYLKNPLGAFIF 252
R LK+PL
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
+ L + D++CL YPSLSQLK+L L H + LEPL LLEKVAATL+TL L DC
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
I D +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHT LS L LE YPAP ESLD
Sbjct: 361 IGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425
+G V E+LTP++AELMR LREVR+P RIFFGPV CP CG P+E+++F+ C
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
>gi|194306638 PRAME family member 3 [Homo sapiens]
Length = 481
Score = 536 bits (1380), Expect = e-152
Identities = 283/473 (59%), Positives = 333/473 (70%), Gaps = 48/473 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQAP RLLELAGQSLL +Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D L+AQKVRPRR KLQVL+LRDVDENFWTIWSGAR
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 122
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSCSPEAMSKRQTVEDCPR GE+QPLKVF+D+CLKE +DE LS+ GW+ +RRG VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C +F YLSQM NLR+LF
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFIRYLSQMRNLRKLFIS 242
Query: 241 ------------------------------------------------RYLKNPLGAFIF 252
R L++PL
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Query: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
+ +L D++CL +YPSLSQLK+L L H + LEPL LLEKVAATL+TL L DC
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
Query: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
I+D +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHT LS L LE YPAP ESLD
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
Query: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425
+G V E+LTP++AELMR LREVR+PKRIFFGPV CP CG+ P+E+++F+ C
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
>gi|194306635 PRAME family member 19 [Homo sapiens]
Length = 479
Score = 534 bits (1375), Expect = e-152
Identities = 280/473 (59%), Positives = 329/473 (69%), Gaps = 48/473 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS QAP RLLELAGQSLLR+Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D L+AQKVRPRRWKLQVL++RDVDENFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSCSPEAMSKRQTVEDCPR GE+QPLKVF+D+CLKE ++DE LS+ GW+ +RR VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C + + YLSQM NLR+LF
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 ------------------------------------------------RYLKNPLGAFIF 252
R LK+PL
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
+ L + D++CL YPSLSQLK+L L H + LEPL LLEKVAATL+TL L DC
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
I +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHT LS L LE YPAP ESLD
Sbjct: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425
+G V E+LTP++AELMR LREVR+P RIFFGPV CP CG P+E+++F+ C
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
>gi|153792140 PRAME family member 14 [Homo sapiens]
Length = 426
Score = 526 bits (1354), Expect = e-149
Identities = 268/425 (63%), Positives = 313/425 (73%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEAF R F+ L +MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMKT HLETL+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSC PE MSKRQT EDCPRMGE QPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
CCSK+ NY P R L+ IY +SIQ+LE+ K YL +M NLR+L F
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 RYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVA 300
R L+NPL + YL + DM+CLSQYPSL LK L L ++L++ LEPLG LLEK+A
Sbjct: 241 RCLQNPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIA 300
Query: 301 ATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLG 360
A+L+TL+L+ C+I QL +LP LSHCSQLTTF F N SM ALKDLL HT GLSKL
Sbjct: 301 ASLETLILEGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLS 360
Query: 361 LELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKV 420
LE YPAP ESL+ V+WEI +RAELM TLREVRQPKRIF GP PCP+CGS PSE++
Sbjct: 361 LETYPAPEESLNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEEL 420
Query: 421 DFHLC 425
+ HLC
Sbjct: 421 ELHLC 425
>gi|12738831 PRAME family member 1 [Homo sapiens]
Length = 474
Score = 513 bits (1321), Expect = e-145
Identities = 273/473 (57%), Positives = 317/473 (67%), Gaps = 48/473 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEAFS R F+ L +MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMKT HLETL+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSC PE SKRQT EDCPRMGE QPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
CCSK+ NY P R L+ IY +SIQELE+ K YL +M NLR+L F
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 RY------------------------------------------------LKNPLGAFIF 252
R L+NPL
Sbjct: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
+ YL + DM+CLSQYPSL LK L L ++L++ LEPLG LLEK+AA+LKTL+L+ C+
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
Query: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
I QL +LPALS CSQLTTF F N S++ALKDLLRHT GLSKL LE YPAP ESL+
Sbjct: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425
VNWEI TP+RAELM TLREVRQPKRIF GP PCP+CGS PSE+++ HLC
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|66954681 PRAME family member 13 [Homo sapiens]
Length = 474
Score = 506 bits (1303), Expect = e-143
Identities = 269/473 (56%), Positives = 314/473 (66%), Gaps = 48/473 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEAF R F+ L +MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMKT HLETL+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSC PE MSKRQT EDCPRMGE QPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
CCSK+ NY P R L+ IY +SIQ+LE+ K YL +M NLR+L F
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 RY------------------------------------------------LKNPLGAFIF 252
R L+NPL
Sbjct: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
+ YL + DM+CLSQYPSL LK L L ++L++ LEPLG LLEK+AA+L+TL+L+ C+
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360
Query: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
I QL +LP LSHCSQLTTF F N SM ALKDLLRHT GLSKL LE YPAP ESL+
Sbjct: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425
V+WEI +RAELM TLREVRQPKRIF GP PCP+CGS PSE+++ HLC
Sbjct: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|12738834 PRAME family member 2 [Homo sapiens]
Length = 474
Score = 491 bits (1265), Expect = e-139
Identities = 264/473 (55%), Positives = 311/473 (65%), Gaps = 48/473 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +F EAFS R F+ L +MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPL SLMKT HLE L+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSC PEAMSKRQT EDCPR GE QPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
CCSK+ NY P R L+ IY +SI ELE+ C + K YL +M L +L F
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
Query: 241 ------------------------------------------------RYLKNPLGAFIF 252
R L+NPL
Sbjct: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
+ L + D++CLSQ+PSL LK L L ++L++ LEPLG LLEK+AA+L+TLVL+ C+
Sbjct: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
Query: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
I QL +LP LS CSQLTTF F N S++ALKDLLRHT GLSKL LE YPAP ESL+
Sbjct: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425
VNWEI TP+RAELM TLRE RQPKRIF GP PCP+CGS PSE+++ HLC
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
Length = 474
Score = 471 bits (1211), Expect = e-133
Identities = 259/461 (56%), Positives = 305/461 (66%), Gaps = 47/461 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQAP RLLELAGQSLL +Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D L+AQKVRPRR KLQVL+LRDVDENFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
LSCSPEAMSKRQTVEDCPR GE+QPLKVF+D+CLKE +DE LS+ GW+ +RRG VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C +F+PYLSQM NLR+LF
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
Query: 241 ---RY--------------------------------------------LKNPLGAFIFS 253
RY LK L +
Sbjct: 241 DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTIT 300
Query: 254 DAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCRI 313
+ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L DC I
Sbjct: 301 NCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGI 360
Query: 314 QDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDY 373
D Q+ +LPALS C +L TF+F GN SM L++LL HT L L LELYPAP ES
Sbjct: 361 IDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYGA 420
Query: 374 KGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGS 414
G + W T IRAELM+ +R++R PKRI FG CP CG+
Sbjct: 421 DGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGN 461
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 420 bits (1080), Expect = e-117
Identities = 236/462 (51%), Positives = 298/462 (64%), Gaps = 51/462 (11%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++AP RLLELA Q LLR+Q L I T++ELPRE+FP +FMEAFS RR E LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F RLPLGSLMK+PHLE+L++VL G+D L+ Q+VRPR+ KLQVLDLR+VDENF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGA- 119
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
+ PEA+S++QT ++CP G +QP VFIDLCLK TLDECL++L W R+GL+H+
Sbjct: 120 -TASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLREL--- 237
CC ++Q + MP S +L + D IQE+EV L+ KFAPYL QM NLR+L
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 238 ---------------FFPRY-------------------------------LKNPLGAFI 251
F R+ L+ L +
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
Query: 252 FSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDC 311
+D L++ D++ LS PS+ QLKEL L + + EPL LLE+V ATL+TL L+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
Query: 312 RIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESL 371
I D QL +LP LS CSQL+TF+F GN SM AL++LLRHT GLSKL LELYPAPLES
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 372 DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCG 413
D +G + W + AELM+TLR++RQPK I F VPCP CG
Sbjct: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCG 460
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 420 bits (1080), Expect = e-117
Identities = 236/462 (51%), Positives = 298/462 (64%), Gaps = 51/462 (11%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++AP RLLELA Q LLR+Q L I T++ELPRE+FP +FMEAFS RR E LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F RLPLGSLMK+PHLE+L++VL G+D L+ Q+VRPR+ KLQVLDLR+VDENF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGA- 119
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
+ PEA+S++QT ++CP G +QP VFIDLCLK TLDECL++L W R+GL+H+
Sbjct: 120 -TASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLREL--- 237
CC ++Q + MP S +L + D IQE+EV L+ KFAPYL QM NLR+L
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 238 ---------------FFPRY-------------------------------LKNPLGAFI 251
F R+ L+ L +
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
Query: 252 FSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDC 311
+D L++ D++ LS PS+ QLKEL L + + EPL LLE+V ATL+TL L+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
Query: 312 RIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESL 371
I D QL +LP LS CSQL+TF+F GN SM AL++LLRHT GLSKL LELYPAPLES
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 372 DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCG 413
D +G + W + AELM+TLR++RQPK I F VPCP CG
Sbjct: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCG 460
>gi|124249372 PRAME family member 12 [Homo sapiens]
Length = 483
Score = 419 bits (1078), Expect = e-117
Identities = 238/462 (51%), Positives = 295/462 (63%), Gaps = 51/462 (11%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MSLQAP RLLELA QSLLR++ L I TL+ELPRE+FP +FMEAF+ R E L MVQAWP
Sbjct: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F LPLGSLMK+ +LE +AVL GLD L+AQKVRPRRWKLQVLDLR+VDENFW IWSGA
Sbjct: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
L SPEA+SKR+T +CPR G +QPL V +DLC K LDECL++ W R+GL+H+
Sbjct: 121 AL--SPEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLREL--- 237
CC ++Q + + +L + D IQE+EV L+ +FAPYL QM NLR+L
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
Query: 238 ----------------------------FFP------------------RYLKNPLGAFI 251
+F R L+ PL +
Sbjct: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
Query: 252 FSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDC 311
++ L++ D++ LS PS+ QLKEL L I + EPL VLLE+ ATL+TL L+DC
Sbjct: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
Query: 312 RIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESL 371
I D QL +LPALS CSQL+TF+F GN SM AL++LLRHT GLSKL LELYPAPLES
Sbjct: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 372 DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCG 413
D +G + W + + AELM+TLR++RQPK I F VPCP CG
Sbjct: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCG 460
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 417 bits (1073), Expect = e-117
Identities = 235/462 (50%), Positives = 297/462 (64%), Gaps = 51/462 (11%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++AP RLLELA Q LLR+Q L I T++ELPRE+FP +FMEAFS RR E LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F RLPLGSLMK+PHLE+L++VL G+D L+ Q+VRPR+ KLQVLDLR+VDENF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGA- 119
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
+ PEA+S++QT ++CP G +QP VFIDLCLK TLDECL++L W R+GL+H+
Sbjct: 120 -TASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLREL--- 237
CC ++Q + MP S +L + D IQE+EV L+ KFAPYL QM NLR+L
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 238 ---------------FFPRY-------------------------------LKNPLGAFI 251
F R+ L+ L +
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
Query: 252 FSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDC 311
+D L++ D++ LS PS+ QLKEL L + + EPL LLE+V ATL+TL L+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
Query: 312 RIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESL 371
I D QL +LP LS CSQL+TF+F GN SM AL++LLRHT GLSKL LELYPAPLES
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 372 DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCG 413
D +G + W + AELM+T R++RQPK I F VPCP CG
Sbjct: 419 DTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCG 460
>gi|153792112 PRAME family member 20 [Homo sapiens]
Length = 475
Score = 396 bits (1017), Expect = e-110
Identities = 228/462 (49%), Positives = 278/462 (60%), Gaps = 48/462 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++ P RLLELAG+SLLR++ L I TL+ELP E+FP +FMEAFS R EALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
FLRLPLGSLMK P ET QAVL GLD L+ +VR RRWKLQVLDL+DV ENFW +WS A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C P AM R+ V+DCPRM +QPL VFIDLCLK TLDE + LF W+ R GLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFF- 239
CC K++ M + RN+L+ + D IQE+EV +L +F PYL QM NLR+L
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 240 ---PRY--------------------------------------------LKNPLGAFIF 252
RY LK L
Sbjct: 241 DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILAI 300
Query: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
++ L + D++ LS+YPS+ QLK L L + L PL VLLEKVAATL+ L L DC
Sbjct: 301 TNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDCG 360
Query: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
I D Q+ +LPALS C +LTTF+F GN S L++LL HT L+ L LELYPAP ES D
Sbjct: 361 IVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESYD 420
Query: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGS 414
+G V + AELM +R +R+P+RI F CP CG+
Sbjct: 421 VRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGN 462
>gi|153945800 PRAME family member 21 [Homo sapiens]
Length = 475
Score = 396 bits (1017), Expect = e-110
Identities = 228/462 (49%), Positives = 278/462 (60%), Gaps = 48/462 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++ P RLLELAG+SLLR++ L I TL+ELP E+FP +FMEAFS R EALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
FLRLPLGSLMK P ET QAVL GLD L+ +VR RRWKLQVLDL+DV ENFW +WS A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C P AM R+ V+DCPRM +QPL VFIDLCLK TLDE + LF W+ R GLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFF- 239
CC K++ M + RN+L+ + D IQE+EV +L +F PYL QM NLR+L
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 240 ---PRY--------------------------------------------LKNPLGAFIF 252
RY LK L
Sbjct: 241 DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILAI 300
Query: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
++ L + D++ LS+YPS+ QLK L L + L PL VLLEKVAATL+ L L DC
Sbjct: 301 TNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDCG 360
Query: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
I D Q+ +LPALS C +LTTF+F GN S L++LL HT L+ L LELYPAP ES D
Sbjct: 361 IVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESYD 420
Query: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGS 414
+G V + AELM +R +R+P+RI F CP CG+
Sbjct: 421 VRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGN 462
>gi|148356236 PRAME family member 15 [Homo sapiens]
Length = 478
Score = 381 bits (978), Expect = e-106
Identities = 221/463 (47%), Positives = 274/463 (59%), Gaps = 49/463 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++ P RLLELAG+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F RLPL L+K P LE QAVL GLD L+ Q VRPRRWKLQVLDL+DV ENFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C A ++ V+DCPRM RQPL VF++L LK TLDE L+YL W+ R+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFF- 239
CC K++ MP + R++L+ + D IQE+EV K L +F PYL M NL++L
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
Query: 240 ----PRY--------------------------------------------LKNPLGAFI 251
RY LK L
Sbjct: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
Query: 252 FSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDC 311
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L DC
Sbjct: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
Query: 312 RIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESL 371
I D Q+ +LPALS C +L TF+F GN M L++LL HT L L +ELYPAP ES
Sbjct: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
Query: 372 DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGS 414
G + W IRAELM +R++R PKRI F CP CG+
Sbjct: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465
>gi|61102721 PRAME family member 9 [Homo sapiens]
Length = 478
Score = 381 bits (978), Expect = e-106
Identities = 221/463 (47%), Positives = 274/463 (59%), Gaps = 49/463 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++ P RLLELAG+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F RLPL L+K P LE QAVL GLD L+ Q VRPRRWKLQVLDL+DV ENFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C A ++ V+DCPRM RQPL VF++L LK TLDE L+YL W+ R+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFF- 239
CC K++ MP + R++L+ + D IQE+EV K L +F PYL M NL++L
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
Query: 240 ----PRY--------------------------------------------LKNPLGAFI 251
RY LK L
Sbjct: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
Query: 252 FSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDC 311
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L DC
Sbjct: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
Query: 312 RIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESL 371
I D Q+ +LPALS C +L TF+F GN M L++LL HT L L +ELYPAP ES
Sbjct: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
Query: 372 DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGS 414
G + W IRAELM +R++R PKRI F CP CG+
Sbjct: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465
>gi|61696142 PRAME family member 5 [Homo sapiens]
Length = 476
Score = 379 bits (974), Expect = e-105
Identities = 220/463 (47%), Positives = 275/463 (59%), Gaps = 49/463 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++ P RLLELAG+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F RLPL L+K P LE QAVL GLD L+ Q V PRRWKLQVLDL+DV ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C A ++ V+DCPRM +QPL VF++L LK TLDE L+ L W+ R+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFF- 239
CC K++ MP + R++L+ + D IQE+EV K L +F PYL M NL++L
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 240 ----PRY--------------------------------------------LKNPLGAFI 251
RY LK L
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 252 FSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDC 311
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L DC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 312 RIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESL 371
I D Q+ +LPALS C +L TF+F GN SM L++LL HT L L +ELYPAP ES
Sbjct: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 372 DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGS 414
D G + W IRAELM+ +R++R PKRI F CP CG+
Sbjct: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGN 463
>gi|58219004 PRAME family member 6 [Homo sapiens]
Length = 476
Score = 379 bits (973), Expect = e-105
Identities = 220/463 (47%), Positives = 274/463 (59%), Gaps = 49/463 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++ P RLLELAG+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F RLPL L+K P LE QAVL GLD L+ Q V PRRWKLQVLDL+DV ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C A + V+DCPRM +QPL VF++L LK TLDE L+ L W+ R+ L+HL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFF- 239
CC K++ MP + R++L+ + D IQE+EV K L +F PYL M NL++L
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 240 ----PRY--------------------------------------------LKNPLGAFI 251
RY LK L
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 252 FSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDC 311
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L DC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 312 RIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESL 371
I D Q+ +LPALS C +L TF+F GN SM L++LL HT L L +ELYPAP ES
Sbjct: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 372 DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGS 414
D G + W IRAELM+ +R++R PKRI F CP CG+
Sbjct: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGN 463
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 378 bits (970), Expect = e-105
Identities = 220/463 (47%), Positives = 275/463 (59%), Gaps = 49/463 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++ P RLLELAG+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F RLPL L+K P LE QAVL GLD L+ Q V PRRWKLQVLDL+DV ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C A ++ V+DCPRM +QPL VF++L LK TLDE L+ L W+ R+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFF- 239
CC K++ MP + R++L+ + D IQE+EV K L +F PYL M NL++L
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 240 ----PRY--------------------------------------------LKNPLGAFI 251
RY LK L
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 252 FSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDC 311
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L DC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 312 RIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESL 371
I D Q+ +LPALS C +L TF+F GN SM L++LL HT L L +ELYPAP ES
Sbjct: 361 GIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 372 DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGS 414
D G + W IRAELM+ +R++R PKRI F CP CG+
Sbjct: 421 DADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGN 463
>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
Length = 513
Score = 374 bits (961), Expect = e-104
Identities = 220/462 (47%), Positives = 270/462 (58%), Gaps = 49/462 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS++ P RLLEL G+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQAWP
Sbjct: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F RLPL L+K P LE QAVL GLD L+ Q VRPRRWKLQVLDL+DV ENFW +WS A
Sbjct: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C A + V+DCPRM ERQPL VF++L LK TLDE L+ L W+ RR L+HL
Sbjct: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFF- 239
CC K++ MP + R++L+ + D IQE+EV K L +F PYL + NL++L
Sbjct: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
Query: 240 ----PRY--------------------------------------------LKNPLGAFI 251
RY LK L
Sbjct: 278 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 337
Query: 252 FSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDC 311
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L DC
Sbjct: 338 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 397
Query: 312 RIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESL 371
I D Q+ +LPALS C +L TF+F GN M L++LL HT L L LELYPAP ES
Sbjct: 398 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQESY 457
Query: 372 DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCG 413
G + W IRAELM+ +R +R PKRI F CP G
Sbjct: 458 GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHG 499
>gi|59958373 PRAME family member 4 [Homo sapiens]
Length = 478
Score = 372 bits (956), Expect = e-103
Identities = 219/463 (47%), Positives = 271/463 (58%), Gaps = 49/463 (10%)
Query: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
MS+ P RLLELAG+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQ+WP
Sbjct: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
Query: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
F RLPL L+K P LE QAVL GLD L+ VRPRRWKLQVLDL+DV ENFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
C A ++ VEDCPRM RQPL VF++L LK TLDE L+ L W+ R+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
Query: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFF- 239
CC K++ MP + R++L+ + D IQE+EV K L +F PYL M NL++L
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
Query: 240 ----PRY--------------------------------------------LKNPLGAFI 251
RY LK L
Sbjct: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLT 302
Query: 252 FSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDC 311
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L DC
Sbjct: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
Query: 312 RIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESL 371
I D Q+ +LPALS C +L TF+F GN M L++LL HT L L +ELYPAP ES
Sbjct: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
Query: 372 DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGS 414
G + W IRAELM +R++R PKRI F CP CG+
Sbjct: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465
>gi|226437621 PRAME family member 11 [Homo sapiens]
Length = 436
Score = 328 bits (840), Expect = 7e-90
Identities = 196/422 (46%), Positives = 238/422 (56%), Gaps = 49/422 (11%)
Query: 41 MEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKL 100
MEAFS RR EALKLMVQAWPF RLPL L+K P LE QAVL GLD L+ Q VRPRRWKL
Sbjct: 1 MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
Query: 101 QVLDLRDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTL 160
QVLDL+DV ENFW +WS A C A + V+DCPRM ERQPL VF++L LK TL
Sbjct: 61 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
Query: 161 DECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNK 220
DE L+ L W+ RR L+HLCC K++ MP + R++L+ + D IQE+EV K L
Sbjct: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
Query: 221 TGKFAPYLSQMSNLRELFF-----PRY--------------------------------- 242
+F PYL + NL++L RY
Sbjct: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
Query: 243 -----------LKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEP 291
LK L ++ L + D++ LSQ PS+SQLK L L I + L P
Sbjct: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
Query: 292 LGVLLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLR 351
L +LLEKVAATL+ L L DC I D Q+ +LPALS C +L TF+F GN M L++LL
Sbjct: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
Query: 352 HTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPT 411
HT L L LELYPAP ES G + W IRAELM+ +R +R PKRI F CP
Sbjct: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
Query: 412 CG 413
G
Sbjct: 421 HG 422
>gi|46249373 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 325 bits (832), Expect = 6e-89
Identities = 198/470 (42%), Positives = 267/470 (56%), Gaps = 61/470 (12%)
Query: 5 APSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRL 64
+P RL+ELAGQSLL+++ L I L+ LPRE+FP +FM AF R + LK MVQAWPF L
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKTP--HLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLR-DVDENFWTIWSGARV 121
PLG LMK HLET +AVL GLD L+AQ+VRPRRWKLQVLDLR + ++FWT+WSG R
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 LSCS---PEA---MSKRQTVEDCPRMGERQ--PLKVFIDLCLKESTLDECLSYLFGWIHY 173
S PEA M+K++ V+ E+ P++V +DL LKE DE SYL +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSN 233
++ ++ LCC K++ ++MP + +L+ + DSI++LEV L KF+PYL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRELFFP-------------------------------------------------RYLK 244
LR L R++
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
Query: 245 NPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLK 304
NPL ++ L++ D+ LSQ PS+SQL L L +++ EPL LLE+ +ATL+
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
Query: 305 TLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELY 364
LV +C I D QL LLP+LSHCSQLTT +F+GN S++AL+ LL+H GLS L LY
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
Query: 365 PAPLESL-DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCG 413
P PLES D G ++ E L + A L L E+ +P ++ PCP CG
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
>gi|46249371 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 325 bits (832), Expect = 6e-89
Identities = 198/470 (42%), Positives = 267/470 (56%), Gaps = 61/470 (12%)
Query: 5 APSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRL 64
+P RL+ELAGQSLL+++ L I L+ LPRE+FP +FM AF R + LK MVQAWPF L
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKTP--HLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLR-DVDENFWTIWSGARV 121
PLG LMK HLET +AVL GLD L+AQ+VRPRRWKLQVLDLR + ++FWT+WSG R
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 LSCS---PEA---MSKRQTVEDCPRMGERQ--PLKVFIDLCLKESTLDECLSYLFGWIHY 173
S PEA M+K++ V+ E+ P++V +DL LKE DE SYL +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSN 233
++ ++ LCC K++ ++MP + +L+ + DSI++LEV L KF+PYL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRELFFP-------------------------------------------------RYLK 244
LR L R++
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
Query: 245 NPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLK 304
NPL ++ L++ D+ LSQ PS+SQL L L +++ EPL LLE+ +ATL+
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
Query: 305 TLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELY 364
LV +C I D QL LLP+LSHCSQLTT +F+GN S++AL+ LL+H GLS L LY
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
Query: 365 PAPLESL-DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCG 413
P PLES D G ++ E L + A L L E+ +P ++ PCP CG
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,320,443
Number of Sequences: 37866
Number of extensions: 713765
Number of successful extensions: 2191
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2075
Number of HSP's gapped (non-prelim): 91
length of query: 426
length of database: 18,247,518
effective HSP length: 105
effective length of query: 321
effective length of database: 14,271,588
effective search space: 4581179748
effective search space used: 4581179748
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.