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Search of human proteins with 23957696
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23957696 hypothetical protein LOC149647 [Homo sapiens]
(594 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23957696 hypothetical protein LOC149647 [Homo sapiens] 1163 0.0
gi|222418633 family with sequence similarity 71, member B [Homo ... 503 e-142
gi|23503301 hypothetical protein LOC196472 [Homo sapiens] 261 1e-69
gi|89363024 hypothetical protein LOC161142 [Homo sapiens] 107 4e-23
gi|76253859 hypothetical protein LOC112703 [Homo sapiens] 106 5e-23
gi|223972704 hypothetical protein LOC284418 [Homo sapiens] 92 1e-18
gi|14211935 testes development-related NYD-SP18 [Homo sapiens] 85 2e-16
gi|193083150 hypothetical protein LOC346653 isoform b [Homo sapi... 73 8e-13
gi|149192824 hypothetical protein LOC346653 isoform a [Homo sapi... 65 2e-10
gi|161016767 mucin 21 [Homo sapiens] 55 1e-07
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 53 7e-07
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 53 7e-07
gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens] 52 2e-06
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 50 4e-06
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 49 1e-05
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 48 2e-05
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 48 2e-05
gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens] 47 4e-05
gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens] 47 4e-05
gi|24497554 homeobox A13 [Homo sapiens] 47 6e-05
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 46 8e-05
gi|57864582 hornerin [Homo sapiens] 46 1e-04
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 45 1e-04
gi|60097902 filaggrin [Homo sapiens] 45 2e-04
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 43 7e-04
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 43 7e-04
gi|40068059 CBF1 interacting corepressor [Homo sapiens] 42 0.002
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens] 42 0.002
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
>gi|23957696 hypothetical protein LOC149647 [Homo sapiens]
Length = 594
Score = 1163 bits (3009), Expect = 0.0
Identities = 594/594 (100%), Positives = 594/594 (100%)
Query: 1 MNADFLLPYYTAQSGSSMSMFDTTMGKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVI 60
MNADFLLPYYTAQSGSSMSMFDTTMGKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVI
Sbjct: 1 MNADFLLPYYTAQSGSSMSMFDTTMGKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVI 60
Query: 61 DVHNRVRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTR 120
DVHNRVRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTR
Sbjct: 61 DVHNRVRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTR 120
Query: 121 LLPLRFVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPMES 180
LLPLRFVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPMES
Sbjct: 121 LLPLRFVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPMES 180
Query: 181 NSSTCGIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAYAG 240
NSSTCGIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAYAG
Sbjct: 181 NSSTCGIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAYAG 240
Query: 241 GEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAA 300
GEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAA
Sbjct: 241 GEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAA 300
Query: 301 ANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASM 360
ANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASM
Sbjct: 301 ANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASM 360
Query: 361 SLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGC 420
SLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGC
Sbjct: 361 SLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGC 420
Query: 421 KEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGN 480
KEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGN
Sbjct: 421 KEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGN 480
Query: 481 PGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTK 540
PGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTK
Sbjct: 481 PGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTK 540
Query: 541 VVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGLEMVGSMTPDIMETVTFEAH 594
VVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGLEMVGSMTPDIMETVTFEAH
Sbjct: 541 VVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGLEMVGSMTPDIMETVTFEAH 594
>gi|222418633 family with sequence similarity 71, member B [Homo
sapiens]
Length = 605
Score = 503 bits (1295), Expect = e-142
Identities = 300/612 (49%), Positives = 396/612 (64%), Gaps = 31/612 (5%)
Query: 1 MNADFLLPYYTAQSGSSMSMFDTTMGKLQRQLY-KGEYDIFKYAPIFESDFIQITKRGEV 59
M+ + LPYYTA S SSMS F T+MG LQRQLY +GEY+IFKYAP+FES+FIQI K+GEV
Sbjct: 1 MSNESCLPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEV 60
Query: 60 IDVHNRVRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELT 119
IDVHNRVRMVT+GI TSPILPLPDVM+LA+P CE++ G+ K + R+ K LELT
Sbjct: 61 IDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELT 120
Query: 120 RLLPLRFVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPME 179
RLLPL+FV+IS+ DHEKQQLRLK ATGR+ YLQLCP+ DTR+DLF YWEKL+YLLRPP+E
Sbjct: 121 RLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVE 180
Query: 180 SNSSTCGIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAYA 239
S ST + + D ED +SL A L +GDQ + L+ +V ATS+AYA
Sbjct: 181 SYCSTPTLLSGDAP-----PEDNKSLVAAELHREGDQSET---GLYKPCDVSAATSSAYA 232
Query: 240 GGEGLQNDFNKPTNVLNASIPKTSTELAEE----PATGGIKEAAAAG------AAAGAAT 289
GGEG+Q+ + +A+ P TST A E GG+ A A A AGAA
Sbjct: 233 GGEGIQHASH---GTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAM 289
Query: 290 GTVAGALSVAAANSA-PGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAA 348
GA+S+A SA PGQV+ A+AGAA + G N+ + ++AG A+++ +A+ GAA
Sbjct: 290 SPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAA 349
Query: 349 GKSSEHVSSA---SMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLS 405
S E S++ + SLS++ S+S A AG + TS+ AAE A GP +ST QS+ +S
Sbjct: 350 STSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMS 409
Query: 406 GQHGRER-TQASAEGCKEGRERRE-KDRALGR-SSHRRRTGESRHKTRGDKIAQKSSSRS 462
+ G ++ +Q SAE E +ERRE KDR R SSH R+ GES + GDK + SS RS
Sbjct: 410 ERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRS 469
Query: 463 SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGS-SK 521
+ H+ RDDKKEKG N RH S K +H+ KESRT+ + G++ +S+G+ K
Sbjct: 470 ASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQK 529
Query: 522 GLGRVSSFLRNVRANLTTKVVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGLEMV-GS 580
++SSFLR++RA +K T H R+VD++AKM E+ A E A+GGQ LEM+ G+
Sbjct: 530 KASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELEMISGT 589
Query: 581 MTPDIMETVTFE 592
MT + E + FE
Sbjct: 590 MTSEKTEMIVFE 601
>gi|23503301 hypothetical protein LOC196472 [Homo sapiens]
Length = 241
Score = 261 bits (668), Expect = 1e-69
Identities = 136/233 (58%), Positives = 172/233 (73%), Gaps = 1/233 (0%)
Query: 6 LLPYYTAQSGSSMSMFDTTMGKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNR 65
+LPYYTAQS +M MF+T+MGKLQRQLYKGEY IF+YAP+FESDFIQI+KRGEVIDVHNR
Sbjct: 6 MLPYYTAQSSPAMGMFNTSMGKLQRQLYKGEYTIFRYAPMFESDFIQISKRGEVIDVHNR 65
Query: 66 VRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLR 125
RMVTMGI RTSP L LPDVMLLARPA C+ A G AT++++ A+ LELTRLLPL
Sbjct: 66 ARMVTMGIVRTSPCLTLPDVMLLARPAAVCDN-ARCGPATQKRESPPAEILELTRLLPLM 124
Query: 126 FVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPMESNSSTC 185
FV+I++ + K+QL LK ATGRS YLQLCP D +DLF +WE L+Y+LRPP+E+ S T
Sbjct: 125 FVKITIHNSVKKQLHLKLATGRSFYLQLCPPSDASEDLFVHWENLVYILRPPVEAYSDTR 184
Query: 186 GIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAY 238
I A + + V +E +RS ++ +++Q I LHM +E+ G+T Y
Sbjct: 185 AILAGNTLDSSVLEEVQRSPVGYAMKFCEEKEQFRISRLHMNAEMFGSTYCDY 237
>gi|89363024 hypothetical protein LOC161142 [Homo sapiens]
Length = 422
Score = 107 bits (266), Expect = 4e-23
Identities = 63/147 (42%), Positives = 84/147 (57%), Gaps = 1/147 (0%)
Query: 28 LQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNRVRMVTMGIARTSPILPLPDVML 87
LQ L GEY F P+ ES+FIQ+ +RGE I +HNR VT+GI +S +P+VML
Sbjct: 29 LQNMLDGGEYAPFVSPPMLESNFIQVNRRGESIYLHNRANWVTVGICFSSSTHKIPNVML 88
Query: 88 LARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEKQQLRLKFATGR 147
LA G ++ A+ L LTR LPL+FV +SV D E L++K +GR
Sbjct: 89 LAHLTPGAQKDT-ETLFKSLLTSPPAEKLVLTRFLPLQFVTLSVHDAENMSLKVKLVSGR 147
Query: 148 SCYLQLCPALDTRDDLFAYWEKLIYLL 174
+ YLQLC + +D LF+ W LI LL
Sbjct: 148 AYYLQLCTSAYKQDTLFSQWVALISLL 174
>gi|76253859 hypothetical protein LOC112703 [Homo sapiens]
Length = 231
Score = 106 bits (265), Expect = 5e-23
Identities = 64/149 (42%), Positives = 86/149 (57%), Gaps = 24/149 (16%)
Query: 27 KLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNRVRMVTMGIARTSPILPLPDVM 86
+LQR L GE+D F+ PIFES+F+Q+T+ GEV + VTMG+A +SP L LPD++
Sbjct: 95 RLQRYLQSGEFDQFRDFPIFESNFVQVTRLGEVANE------VTMGVAASSPALELPDLL 148
Query: 87 LLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEKQQLRLKFATG 146
LLA PA K +L+L L PL+FV++ V D + QL +K T
Sbjct: 149 LLAGPA------------------KENGHLQLFGLFPLKFVQLFVHDKSRCQLEVKLNTS 190
Query: 147 RSCYLQLCPALDTRDDLFAYWEKLIYLLR 175
R+ YLQL L TRD F W +L+Y LR
Sbjct: 191 RTFYLQLRAPLKTRDREFGQWVRLLYRLR 219
>gi|223972704 hypothetical protein LOC284418 [Homo sapiens]
Length = 922
Score = 92.0 bits (227), Expect = 1e-18
Identities = 56/157 (35%), Positives = 87/157 (55%), Gaps = 24/157 (15%)
Query: 25 MGKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNRVRMVTMGIARTSPILPLPD 84
+G+LQ+ L KGEY + P+FES+F+Q+T +G + V++R + MG+A + P L LPD
Sbjct: 23 LGELQKTLQKGEYLPLRPLPMFESNFVQVTHQGGPVFVNHRTNRLAMGVAASLPGLVLPD 82
Query: 85 VMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEKQQLRLKFA 144
++L+ +PA + + L LTR++PL V + V D +L+L+
Sbjct: 83 ILLIGQPA----------------EDRDCSGLVLTRMIPLDLVHLCVHDLSAWRLKLRLV 126
Query: 145 TGRSCYLQLCPALDTRDD----LFAYWEKLIYLLRPP 177
+GR YL ALD D+ LF W +LI LL+ P
Sbjct: 127 SGRQYYL----ALDAPDNEVGFLFHCWVRLINLLQEP 159
>gi|14211935 testes development-related NYD-SP18 [Homo sapiens]
Length = 344
Score = 84.7 bits (208), Expect = 2e-16
Identities = 58/209 (27%), Positives = 104/209 (49%), Gaps = 22/209 (10%)
Query: 26 GKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNRVRMVTMGIARTSPILPLPDV 85
G L R ++ E+++F + +FES+FIQ+ + DV+ + +G+ + P LPLP++
Sbjct: 57 GLLCRVVHSPEFNLFLDSVVFESNFIQVKRGRNWRDVYKASNTMALGVTSSVPCLPLPNI 116
Query: 86 MLLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEKQQLRLKFAT 145
+L+A + + G Q R A N+ L R+LPLRFV + V DH ++ L+L+ T
Sbjct: 117 LLMA----SVKWHQGQNQTWNRP--SIAPNIFLKRILPLRFVELQVCDHYQRILQLRTVT 170
Query: 146 GRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPMESNS-------------STCGIPAED- 191
+ YL+L P D + +F +W +L+ +L+ + + C P+ D
Sbjct: 171 EKIYYLKLHP--DHPETVFHFWIRLVQILQKGLSITTKDPRILVTHCLVPKNCSSPSGDS 228
Query: 192 MMWMPVFQEDRRSLGAVNLQGKGDQDQVS 220
+ Q + S + L KG+ + +S
Sbjct: 229 KLVQKKLQASQPSESLIQLMTKGESEALS 257
>gi|193083150 hypothetical protein LOC346653 isoform b [Homo
sapiens]
Length = 300
Score = 72.8 bits (177), Expect = 8e-13
Identities = 46/150 (30%), Positives = 81/150 (54%), Gaps = 8/150 (5%)
Query: 26 GKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNRVRMVTMGIARTSPILPLPDV 85
G L + ++ E+++F + +FES+FIQ+TK G DV V +G+ + P LPLP+V
Sbjct: 25 GLLCQLIHSPEFNLFSNSVVFESNFIQVTKPGNWRDVCEGSATVILGVTSSVPSLPLPNV 84
Query: 86 MLLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEKQQLRLKFAT 145
+L+A G T A + L+RLLPL++V + + D ++ LR++ T
Sbjct: 85 LLMANVTW------PQGPFTTWSTPGDAPVINLSRLLPLKYVELRIYDRLQRILRVRTVT 138
Query: 146 GRSCYLQLCPALDTRDDLFAYWEKLIYLLR 175
+ YL+L + +F +W +L+ +L+
Sbjct: 139 EKIYYLKLHE--KHPEIVFQFWVRLVKILQ 166
>gi|149192824 hypothetical protein LOC346653 isoform a [Homo
sapiens]
Length = 309
Score = 65.1 bits (157), Expect = 2e-10
Identities = 46/159 (28%), Positives = 81/159 (50%), Gaps = 17/159 (10%)
Query: 26 GKLQRQLYKGEYDIFKYAPIFESDFIQ---------ITKRGEVIDVHNRVRMVTMGIART 76
G L + ++ E+++F + +FES+FIQ +TK G DV V +G+ +
Sbjct: 25 GLLCQLIHSPEFNLFSNSVVFESNFIQTHVPEADFQVTKPGNWRDVCEGSATVILGVTSS 84
Query: 77 SPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEK 136
P LPLP+V+L+A G T A + L+RLLPL++V + + D +
Sbjct: 85 VPSLPLPNVLLMANVTW------PQGPFTTWSTPGDAPVINLSRLLPLKYVELRIYDRLQ 138
Query: 137 QQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLR 175
+ LR++ T + YL+L + +F +W +L+ +L+
Sbjct: 139 RILRVRTVTEKIYYLKLHE--KHPEIVFQFWVRLVKILQ 175
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 55.5 bits (132), Expect = 1e-07
Identities = 68/322 (21%), Positives = 123/322 (38%), Gaps = 21/322 (6%)
Query: 263 STELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGG 322
S+ + E +T E++ + A AT + + +S A+ + + S +GA+T
Sbjct: 155 SSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSE 214
Query: 323 NKGNMALAGTASMAPNSTKVAVAGAA--GKSSEHVSSASMSLSREGSVSLAIAGVVLTSR 380
++ AGTA+ + +ST + A A +SS S A + + E S + + AG +
Sbjct: 215 SRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAG----TA 270
Query: 381 TAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRR 440
T +E+ ++ V+ +S + SG + +++S +
Sbjct: 271 TNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTA 330
Query: 441 RTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISK 500
ES + G A S S ++ S G +S + G S S+
Sbjct: 331 TNSESSTTSSGASTATNSESSTTSS-----------GASTATNSGSSTTSSGTSTATNSE 379
Query: 501 ESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTKVVGTPHGRDVDVMAKMAERS 560
S S SG S TTS S+ G +S N ++ + T + + A +
Sbjct: 380 SSTVS--SGASTATTSESSTTSSG--ASTATNSESSTVSSGASTATNSESSTTSSGANTA 435
Query: 561 TNVAIAETAEGGQGLEMVGSMT 582
TN + T+ G + G T
Sbjct: 436 TNSGSSVTSAGSGTAALTGMHT 457
Score = 45.4 bits (106), Expect = 1e-04
Identities = 63/307 (20%), Positives = 115/307 (37%), Gaps = 25/307 (8%)
Query: 278 AAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAP 337
++ A + TV+ +S+A + + S +GA+T + + A TA+ +
Sbjct: 84 SSGISTATNSEFSTVSSGISIATNSES----STTSSGASTATNSESSTPSSGASTATNSD 139
Query: 338 NSTKVAVAGAAGKSSEHVSS--ASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPV 395
+ST + A A S +S AS + + E S + + A S ++ + + A
Sbjct: 140 SSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSE 199
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
S+ S + + + RT ++ G E +++ ES + G A
Sbjct: 200 SSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATN----SESSTPSSGAGTA 255
Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTT 515
S S ++ S G G +S G+S S+ S S SG + T
Sbjct: 256 TNSESSTTSS-----------GAGTATNSESSTVSSGISTVTNSESSTPS--SGANTATN 302
Query: 516 SSGSSKGLGRVSSFLRNVRANLTTKVVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGL 575
S S+ G ++ N ++ T+ T + + A +TN + T+ G
Sbjct: 303 SESSTTSSG--ANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTA 360
Query: 576 EMVGSMT 582
GS T
Sbjct: 361 TNSGSST 367
Score = 34.7 bits (78), Expect = 0.25
Identities = 37/171 (21%), Positives = 70/171 (40%), Gaps = 19/171 (11%)
Query: 232 GATSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGT 291
GA++A +G + + TN S+ ++ +T E++ + A AT +
Sbjct: 356 GASTATNSGSSTTSSGTSTATN-------SESSTVSSGASTATTSESSTTSSGASTATNS 408
Query: 292 VAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKS 351
+ +S A+ + + S +GA T G+ A +GTA++ T
Sbjct: 409 ESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHT----------- 457
Query: 352 SEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKS 402
+ H +S ++S ++ G SL + L + + A + AG R S S
Sbjct: 458 TSHSASTAVSEAKPGG-SLVPWEIFLITLVSVVAAVGLFAGLFFCVRNSLS 507
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 53.1 bits (126), Expect = 7e-07
Identities = 41/136 (30%), Positives = 62/136 (45%), Gaps = 16/136 (11%)
Query: 399 QSKSSLSGQH-GRERTQASAEGCKE----GRERREKDRALGRSSHRRRTGESRHKTRGDK 453
+SK S S +H R+RT S ++ + R + R+ RS RRR+ SR K+RG +
Sbjct: 1825 RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRR 1884
Query: 454 IAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLW 513
K + S HR+ ++K K S RD+ K + SRT + RS
Sbjct: 1885 SVSKEKRKRSPKHRSKSRERKRK------RSSSRDNRK-----TVRARSRTPSRRSRSHT 1933
Query: 514 TTSSGSSKGLGRVSSF 529
+ S+ +GR SF
Sbjct: 1934 PSRRRRSRSVGRRRSF 1949
Score = 36.6 bits (83), Expect = 0.067
Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 22/165 (13%)
Query: 362 LSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRE------RTQA 415
+ R S+ I G +L S + +AA P VS+ ++S S ++ + +
Sbjct: 1742 MERLTSLRAGIEGPLLASDVGRDR---SAASPVVSSMPERASESSSEEKDDYEIFVKVKD 1798
Query: 416 SAEGCKEGRER----REKDRALGRSSHRRRTGESRHKTR-----GDKIAQKSSSRSSFSH 466
+ E K+ + R +EK R S +R+ S HK+R A+K SS+S SH
Sbjct: 1799 THEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSK-SH 1857
Query: 467 RANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511
R ++ + + SSR R +G +SKE R RS
Sbjct: 1858 R-SQTRSRSRSRRRRRSSRSRSKSRG--RRSVSKEKRKRSPKHRS 1899
Score = 33.5 bits (75), Expect = 0.57
Identities = 33/124 (26%), Positives = 56/124 (45%), Gaps = 10/124 (8%)
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSS----HRRRTGESRHKTRG 451
S + +SS S H R +T++ + + R R + ++ GR S R+R+ + R K+R
Sbjct: 1845 SRARKRSSKSKSH-RSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRE 1903
Query: 452 DKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKG----VSHTPISKESRTSHK 507
K + SS + + RA + + S R R G S +P S+ SRT +
Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISP-SRRSRTPSR 1962
Query: 508 SGRS 511
R+
Sbjct: 1963 RSRT 1966
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 53.1 bits (126), Expect = 7e-07
Identities = 41/136 (30%), Positives = 62/136 (45%), Gaps = 16/136 (11%)
Query: 399 QSKSSLSGQH-GRERTQASAEGCKE----GRERREKDRALGRSSHRRRTGESRHKTRGDK 453
+SK S S +H R+RT S ++ + R + R+ RS RRR+ SR K+RG +
Sbjct: 1825 RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRR 1884
Query: 454 IAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLW 513
K + S HR+ ++K K S RD+ K + SRT + RS
Sbjct: 1885 SVSKEKRKRSPKHRSKSRERKRK------RSSSRDNRK-----TVRARSRTPSRRSRSHT 1933
Query: 514 TTSSGSSKGLGRVSSF 529
+ S+ +GR SF
Sbjct: 1934 PSRRRRSRSVGRRRSF 1949
Score = 36.6 bits (83), Expect = 0.067
Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 22/165 (13%)
Query: 362 LSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRE------RTQA 415
+ R S+ I G +L S + +AA P VS+ ++S S ++ + +
Sbjct: 1742 MERLTSLRAGIEGPLLASDVGRDR---SAASPVVSSMPERASESSSEEKDDYEIFVKVKD 1798
Query: 416 SAEGCKEGRER----REKDRALGRSSHRRRTGESRHKTR-----GDKIAQKSSSRSSFSH 466
+ E K+ + R +EK R S +R+ S HK+R A+K SS+S SH
Sbjct: 1799 THEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSK-SH 1857
Query: 467 RANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511
R ++ + + SSR R +G +SKE R RS
Sbjct: 1858 R-SQTRSRSRSRRRRRSSRSRSKSRG--RRSVSKEKRKRSPKHRS 1899
Score = 33.5 bits (75), Expect = 0.57
Identities = 33/124 (26%), Positives = 56/124 (45%), Gaps = 10/124 (8%)
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSS----HRRRTGESRHKTRG 451
S + +SS S H R +T++ + + R R + ++ GR S R+R+ + R K+R
Sbjct: 1845 SRARKRSSKSKSH-RSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRE 1903
Query: 452 DKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKG----VSHTPISKESRTSHK 507
K + SS + + RA + + S R R G S +P S+ SRT +
Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISP-SRRSRTPSR 1962
Query: 508 SGRS 511
R+
Sbjct: 1963 RSRT 1966
>gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]
Length = 352
Score = 51.6 bits (122), Expect = 2e-06
Identities = 63/240 (26%), Positives = 97/240 (40%), Gaps = 28/240 (11%)
Query: 275 IKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTAS 334
++ A AG GA G + A A + +A GAA+ D G
Sbjct: 1 MERAGPAGEEGGAREGRLLPRAPGAWVLRACAERAALEVGAASADTG------------- 47
Query: 335 MAPNSTKVAVAGAAGKSSEHVSSASMSLSREGS--VSLAIAGVVLTSRTAAEA-DMDAAA 391
V GA G + ++SA +R+G+ V +G L SR A+ A A+
Sbjct: 48 -------VRGCGARGPAPL-LASAGGGRARDGTWGVRTKGSGAALPSRPASRAAPRPEAS 99
Query: 392 GPPVSTRQSKSSLSG-QHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTR 450
PP+ +++ LSG Q GR R + G + + R + R+ GR S +R+ +SR T
Sbjct: 100 SPPLPLEKARGGLSGPQGGRARGAMAHVGSR--KRSRSRSRSRGRGSEKRKK-KSRKDTS 156
Query: 451 GDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR 510
+ A S R + + + K+K SS S S + S S +S GR
Sbjct: 157 RNCSASTSQGRKASTAPGAEERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGR 216
>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
Length = 819
Score = 50.4 bits (119), Expect = 4e-06
Identities = 80/347 (23%), Positives = 123/347 (35%), Gaps = 41/347 (11%)
Query: 251 PTNVLNASIPKTSTELAEEPATGGIKEAAAA--------------GAAAGAATGTVAGAL 296
P L A++ +T ELA E A + AAA AAAG + G
Sbjct: 18 PGAPLGAALARTPVELAAESAAPALSAAAAGVKILGSGDKKLRRQKAAAGGKKARLRGQK 77
Query: 297 SVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAG--AAGKSSE- 353
A A A + GG + A AGT S+ K G AA S+
Sbjct: 78 GAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRGRKPRRRGQKAAATGSKK 137
Query: 354 -----HVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQH 408
S+A+ S +R A A + S+ + AAAG S SG+
Sbjct: 138 PRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAG--------AKSRSGKK 189
Query: 409 GRER-TQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHR 467
R R ++ + K+GR+R K R G++ R G + R A + SR +
Sbjct: 190 PRRRGAKSRGDEDKKGRQREAKSR-FGKT----RGGRRKKHRRPKPAAGGAKSRRGGGKK 244
Query: 468 ANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVS 527
+ ++ + G SR S G K+ R ++ G++ + +
Sbjct: 245 PQKQRRRGQKAATGGKSRVGKSRGGG-----DKKLRRQGQNAALAGAKRRGAATAGEKPA 299
Query: 528 SFLRNVRANLTTKVVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQG 574
+ R R + GR + +++T A A T GG G
Sbjct: 300 AKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGG 346
Score = 35.8 bits (81), Expect = 0.11
Identities = 61/265 (23%), Positives = 92/265 (34%), Gaps = 22/265 (8%)
Query: 276 KEAAAAGAAAGAATG------TVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMAL 329
++A AAGA + VAGA S + + + A AGA + GGNK +
Sbjct: 511 EKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRGG 570
Query: 330 AGTASMAPNSTKVAVAGAAGKSSE---HVSSASMSLSREGS-------VSLAIAGVVLTS 379
G T A G + ++A ++ SR G A G
Sbjct: 571 GGNKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKSRK 630
Query: 380 RTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHR 439
+ DAAA + S SG + +A G + A R R
Sbjct: 631 KPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPR 690
Query: 440 RRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPIS 499
RR R K+RGD Q ++ + R + + K G G ++ R S S
Sbjct: 691 RR----RAKSRGDG-GQNAAVGINPWQRRGKKPRLGKSRGG-GGAKSRGSGGAKSRGSGG 744
Query: 500 KESRTSHKSGRSLWTTSSGSSKGLG 524
+SR+ K+ S G+ + G
Sbjct: 745 AKSRSGKKAAASKSHGGGGAKRRRG 769
Score = 30.8 bits (68), Expect = 3.7
Identities = 61/280 (21%), Positives = 96/280 (34%), Gaps = 48/280 (17%)
Query: 320 AGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTS 379
AGG K + A G + + L R+G + A+AG
Sbjct: 232 AGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQ-NAALAGA--KR 288
Query: 380 RTAAEA-DMDAAAGPPVSTRQSKSSLSGQH-------------GRERTQASAEGCKEGR- 424
R AA A + AA G + SL GQ+ G++ T+A+A G K G
Sbjct: 289 RGAATAGEKPAAKG---RGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGG 345
Query: 425 ----------ERREKDRALGRSSHRRRTGESRHKTR--GDKIAQKSSSRSSFSHRANRDD 472
+ R+K R G+ R++ + K+R GDK + + R D
Sbjct: 346 GQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRG-------DG 398
Query: 473 KKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRN 532
+K+ NP R + K + P S+ + G + G S+ G R
Sbjct: 399 RKKPRWQNP----RRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRG 454
Query: 533 VRANLTTKVVGTPHGRDVDVMAKMAERSTNVAIAETAEGG 572
+A G D K + + A ++ GG
Sbjct: 455 QKARQKAAEAGAESRGD----KKQGRQKASAAGTKSRGGG 490
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 48.9 bits (115), Expect = 1e-05
Identities = 42/153 (27%), Positives = 67/153 (43%), Gaps = 9/153 (5%)
Query: 379 SRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSH 438
S+ +A + + S R+S+S H R +++S+ R R + S
Sbjct: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSR 240
Query: 439 RRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPI 498
R + R ++RG K +SSSR SHR + +K + + SS R+ + S +
Sbjct: 241 SRSSSRERSRSRGSK--SRSSSR---SHRGSSSPRK-RSYSSSSSSPERNRKRSRSRSSS 294
Query: 499 S---KESRTSHKSGRSLWTTSSGSSKGLGRVSS 528
S K+ RT +S +SSGSS R SS
Sbjct: 295 SGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
Score = 38.5 bits (88), Expect = 0.018
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 7/115 (6%)
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRER-REKDRALG---RSSHRRRTGESRHKTRG 451
S+R S S S R R+++S+ R RE+ R+ G RSS R G S + R
Sbjct: 214 SSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRS 273
Query: 452 DKIAQKSSSRS---SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESR 503
+ S R+ S S ++ D+K++ + R S G SH+ S+
Sbjct: 274 YSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328
Score = 37.0 bits (84), Expect = 0.051
Identities = 32/127 (25%), Positives = 52/127 (40%), Gaps = 8/127 (6%)
Query: 350 KSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHG 409
+SS SS S S SR S S + + SR+++ + S S+S
Sbjct: 212 RSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSK--SRSSSRSHRGSSSP 269
Query: 410 RERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRAN 469
R+R+ +S+ E +R + R+ ++R SR R + S S SH +
Sbjct: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPER------RHRSSSGSSHSGS 323
Query: 470 RDDKKEK 476
R K+K
Sbjct: 324 RSSSKKK 330
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 48.1 bits (113), Expect = 2e-05
Identities = 70/246 (28%), Positives = 94/246 (38%), Gaps = 38/246 (15%)
Query: 287 AATGTVAGALSVAAANSA------PGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNST 340
AA GT A A + AAA+S+ P +V G AGG + A
Sbjct: 62 AAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRR--AGGRQKRRRGPRAGQEAEKRR 119
Query: 341 KVAVA-----GAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPV 395
++ G G SS + + E S + G++L +AA A AAG
Sbjct: 120 VFSLPQPQQDGGGGASSG--GGVTPLVEYEDVSSQSEQGLLLGGASAATAA--TAAGGTG 175
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
+ S +S SG TQ EG E R RR++ + GRS R R R RG A
Sbjct: 176 GSGGSPASSSG------TQRRGEG-SERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEA 228
Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPG--------------SSRHRDSHKGVSHTPISKE 501
KS SR S S + K + G S + RDS S T SKE
Sbjct: 229 SKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKE 288
Query: 502 SRTSHK 507
+++K
Sbjct: 289 PPSAYK 294
Score = 45.1 bits (105), Expect = 2e-04
Identities = 64/240 (26%), Positives = 92/240 (38%), Gaps = 20/240 (8%)
Query: 296 LSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHV 355
L +AA +A +AA A ++ G LA A K AG+ +E
Sbjct: 59 LFLAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKR 118
Query: 356 SSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQA 415
S+ ++ A +G +T E VS++ + L G T A
Sbjct: 119 RVFSLPQPQQDGGGGASSGGGVTPLVEYE---------DVSSQSEQGLLLGG-ASAATAA 168
Query: 416 SAEGCKEGRERREKDRALGRSSHRRRTGE-SRHKTRGDKIAQKSSSRSSFSHRANRDDKK 474
+A G G + SS +R GE S + R D+ + SS RS HR +R
Sbjct: 169 TAAGGTGG-----SGGSPASSSGTQRRGEGSERRPRRDR--RSSSGRSKERHREHRRRDG 221
Query: 475 EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR--SLWTTSSGSSKGLGRVSSFLRN 532
++G SR R SH G ++K +S GR S TSS SS R S R+
Sbjct: 222 QRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRS 281
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 48.1 bits (113), Expect = 2e-05
Identities = 70/246 (28%), Positives = 94/246 (38%), Gaps = 38/246 (15%)
Query: 287 AATGTVAGALSVAAANSA------PGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNST 340
AA GT A A + AAA+S+ P +V G AGG + A
Sbjct: 62 AAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRR--AGGRQKRRRGPRAGQEAEKRR 119
Query: 341 KVAVA-----GAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPV 395
++ G G SS + + E S + G++L +AA A AAG
Sbjct: 120 VFSLPQPQQDGGGGASSG--GGVTPLVEYEDVSSQSEQGLLLGGASAATAA--TAAGGTG 175
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
+ S +S SG TQ EG E R RR++ + GRS R R R RG A
Sbjct: 176 GSGGSPASSSG------TQRRGEG-SERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEA 228
Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPG--------------SSRHRDSHKGVSHTPISKE 501
KS SR S S + K + G S + RDS S T SKE
Sbjct: 229 SKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKE 288
Query: 502 SRTSHK 507
+++K
Sbjct: 289 PPSAYK 294
Score = 45.1 bits (105), Expect = 2e-04
Identities = 64/240 (26%), Positives = 92/240 (38%), Gaps = 20/240 (8%)
Query: 296 LSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHV 355
L +AA +A +AA A ++ G LA A K AG+ +E
Sbjct: 59 LFLAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKR 118
Query: 356 SSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQA 415
S+ ++ A +G +T E VS++ + L G T A
Sbjct: 119 RVFSLPQPQQDGGGGASSGGGVTPLVEYE---------DVSSQSEQGLLLGG-ASAATAA 168
Query: 416 SAEGCKEGRERREKDRALGRSSHRRRTGE-SRHKTRGDKIAQKSSSRSSFSHRANRDDKK 474
+A G G + SS +R GE S + R D+ + SS RS HR +R
Sbjct: 169 TAAGGTGG-----SGGSPASSSGTQRRGEGSERRPRRDR--RSSSGRSKERHREHRRRDG 221
Query: 475 EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR--SLWTTSSGSSKGLGRVSSFLRN 532
++G SR R SH G ++K +S GR S TSS SS R S R+
Sbjct: 222 QRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRS 281
>gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens]
Length = 338
Score = 47.4 bits (111), Expect = 4e-05
Identities = 62/240 (25%), Positives = 98/240 (40%), Gaps = 39/240 (16%)
Query: 275 IKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTAS 334
++ A AG GA G + A A + +A GAA+ D G
Sbjct: 1 MERAGPAGEEGGAREGRLLPRAPGAWVLRACAERAALEVGAASADTG------------- 47
Query: 335 MAPNSTKVAVAGAAGKSSEHVSSASMSLSREGS--VSLAIAGVVLTSRTAAEA-DMDAAA 391
V GA G + ++SA +R+G+ V +G L SR A+ A A+
Sbjct: 48 -------VRGCGARGPAPL-LASAGGGRARDGTWGVRTKGSGAALPSRPASRAAPRPEAS 99
Query: 392 GPPVSTRQSKSSLSG-QHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTR 450
PP+ +++ LSG Q GR R + G + + R + R+ GR S +R+
Sbjct: 100 SPPLPLEKARGGLSGPQGGRARGAMAHVGSR--KRSRSRSRSRGRGSEKRK--------- 148
Query: 451 GDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR 510
K ++K +SR+ S +++ K+K SS S S + S S +S GR
Sbjct: 149 --KKSRKDTSRNC-SASTSQERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGR 205
Score = 31.6 bits (70), Expect = 2.2
Identities = 30/154 (19%), Positives = 64/154 (41%), Gaps = 2/154 (1%)
Query: 282 GAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTK 341
G+ A + + A A+S P + A G + G +G MA G+ + + ++
Sbjct: 79 GSGAALPSRPASRAAPRPEASSPPLPLEKARGGLSGPQGGRARGAMAHVGSRKRSRSRSR 138
Query: 342 VAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSK 401
G+ + + S + S S S + RT + + +++ S+ S
Sbjct: 139 SRGRGSEKRKKKSRKDTSRNCS--ASTSQERSKQKARRRTRSSSSSSSSSSSSSSSSSSS 196
Query: 402 SSLSGQHGRERTQASAEGCKEGRERREKDRALGR 435
SS S GR++ + ++ +++R+K + G+
Sbjct: 197 SSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGK 230
>gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens]
Length = 341
Score = 47.4 bits (111), Expect = 4e-05
Identities = 62/240 (25%), Positives = 98/240 (40%), Gaps = 39/240 (16%)
Query: 275 IKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTAS 334
++ A AG GA G + A A + +A GAA+ D G
Sbjct: 1 MERAGPAGEEGGAREGRLLPRAPGAWVLRACAERAALEVGAASADTG------------- 47
Query: 335 MAPNSTKVAVAGAAGKSSEHVSSASMSLSREGS--VSLAIAGVVLTSRTAAEA-DMDAAA 391
V GA G + ++SA +R+G+ V +G L SR A+ A A+
Sbjct: 48 -------VRGCGARGPAPL-LASAGGGRARDGTWGVRTKGSGAALPSRPASRAAPRPEAS 99
Query: 392 GPPVSTRQSKSSLSG-QHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTR 450
PP+ +++ LSG Q GR R + G + + R + R+ GR S +R+
Sbjct: 100 SPPLPLEKARGGLSGPQGGRARGAMAHVGSR--KRSRSRSRSRGRGSEKRK--------- 148
Query: 451 GDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR 510
K ++K +SR+ S +++ K+K SS S S + S S +S GR
Sbjct: 149 --KKSRKDTSRNC-SASTSQERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGR 205
Score = 31.6 bits (70), Expect = 2.2
Identities = 30/154 (19%), Positives = 64/154 (41%), Gaps = 2/154 (1%)
Query: 282 GAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTK 341
G+ A + + A A+S P + A G + G +G MA G+ + + ++
Sbjct: 79 GSGAALPSRPASRAAPRPEASSPPLPLEKARGGLSGPQGGRARGAMAHVGSRKRSRSRSR 138
Query: 342 VAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSK 401
G+ + + S + S S S + RT + + +++ S+ S
Sbjct: 139 SRGRGSEKRKKKSRKDTSRNCS--ASTSQERSKQKARRRTRSSSSSSSSSSSSSSSSSSS 196
Query: 402 SSLSGQHGRERTQASAEGCKEGRERREKDRALGR 435
SS S GR++ + ++ +++R+K + G+
Sbjct: 197 SSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGK 230
>gi|24497554 homeobox A13 [Homo sapiens]
Length = 388
Score = 46.6 bits (109), Expect = 6e-05
Identities = 41/116 (35%), Positives = 48/116 (41%), Gaps = 16/116 (13%)
Query: 278 AAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAP 337
AAAA AAA AA G G AA +A G S A A AA A N+ +A A +AP
Sbjct: 40 AAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAP 99
Query: 338 NSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGP 393
GAA SA S E S A A + AA A ++ GP
Sbjct: 100 --------GAA--------SAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGP 139
Score = 36.6 bits (83), Expect = 0.067
Identities = 38/154 (24%), Positives = 56/154 (36%), Gaps = 6/154 (3%)
Query: 240 GGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVA 299
GG + ++ NK A+ + A GG AAA A + A A + A
Sbjct: 23 GGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAA 82
Query: 300 AANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSAS 359
AAN Q +A A + G + G A P++ A A AA ++ +S+S
Sbjct: 83 AAN----QCRNLMAHPAPLAPGAASAYSSAPGEA--PPSAAAAAAAAAAAAAAAAAASSS 136
Query: 360 MSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGP 393
G A AA++ AA P
Sbjct: 137 GGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALP 170
Score = 31.6 bits (70), Expect = 2.2
Identities = 25/95 (26%), Positives = 35/95 (36%)
Query: 228 SEVCGATSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGA 287
S A +AA A +N P + + S+ E P + AAAA AAA A
Sbjct: 71 SVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAA 130
Query: 288 ATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGG 322
A + +G A A + AA + G
Sbjct: 131 AAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSG 165
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 46.2 bits (108), Expect = 8e-05
Identities = 57/239 (23%), Positives = 89/239 (37%), Gaps = 9/239 (3%)
Query: 273 GGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGT 332
GG E AAA AAA AA+G G P A A + + + + +
Sbjct: 333 GGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSS 392
Query: 333 ASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAG 392
S + +S++ G +S H S S S SR S S SR+ + + G
Sbjct: 393 RSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRY------SRSRSRGRRHSGGG 446
Query: 393 PPVSTRQSKS-SLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRG 451
R S+S + G +G R S + R RR SS R R+ S +R
Sbjct: 447 SRDGHRYSRSPARRGGYGPRRRSRSRSHSGD-RYRRGGRGLRHHSSSRSRSSWSLSPSRS 505
Query: 452 DKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR 510
+ + S S S +R + + +P +R + + S K +T +G+
Sbjct: 506 RSLTRSRSHSPSPSQSRSRSRSRSQS-PSPSPAREKLTRPAASPAVGEKLKKTEPAAGK 563
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 45.8 bits (107), Expect = 1e-04
Identities = 67/331 (20%), Positives = 127/331 (38%), Gaps = 17/331 (5%)
Query: 212 GKGDQDQVSIQSLHMVSEVCGATSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPA 271
G G Q S QS V G+ ++ G G + ++ + +TS E
Sbjct: 295 GHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESG 354
Query: 272 TGGIKEAAAAGAAAGAAT-----GTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGN 326
+G + G+ +G ++ G+ +G S + + + + S++ + +
Sbjct: 355 SGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRG 414
Query: 327 MALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSR----EGSVSLAIAGVVLTSRTA 382
+G+ + + + +G + S +H + S S GS + G +S
Sbjct: 415 QHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEH 474
Query: 383 AEADMDAAAGPPVSTRQSK-SSLSGQHGRERTQASAEGCKE--GRERREKDRALGRSSHR 439
+ +G S+ + S SGQ R Q S+ G G+ ++LG S H
Sbjct: 475 SSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHG 534
Query: 440 RRTGESRHKTRG--DKIAQKSSSRSSFSHRANRDDKK---EKGCGNPGSSRHRDSHKGVS 494
+G+S +RG + +++SSS + + R + E G G+ H++S G S
Sbjct: 535 SGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQS 594
Query: 495 HTPISKESRTSHKSGRSLWTTSSGSSKGLGR 525
S + H S ++SG S G+
Sbjct: 595 SGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQ 625
Score = 44.7 bits (104), Expect = 2e-04
Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 1/127 (0%)
Query: 402 SSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSR 461
SS GQHG QAS+ G R+ S+ R +G +H + G + R
Sbjct: 371 SSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSS-GSGQSPGHGQR 429
Query: 462 SSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSK 521
S S ++ + G G SS S G S ES + H SG + + SG S
Sbjct: 430 GSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSS 489
Query: 522 GLGRVSS 528
G G+ S
Sbjct: 490 GHGQHGS 496
Score = 44.7 bits (104), Expect = 2e-04
Identities = 56/234 (23%), Positives = 89/234 (38%), Gaps = 24/234 (10%)
Query: 299 AAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKV--AVAGAAGKSSEHVS 356
+++N G VS +G G + G+ S + + + +G + +S +H S
Sbjct: 685 SSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGS 744
Query: 357 SASMSLS--REGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQ 414
S+ +S S + GS S +G + + G + SS GQHG +
Sbjct: 745 SSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHG----SSSGHSSSHGQHGSGTSC 800
Query: 415 ASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKK 474
+S+ G E +A G H +G+ +Q S+ FS +
Sbjct: 801 SSSCGHYESGS----GQASGFGQHESGSGQG--------YSQHGSASGHFSSQGRHGSTS 848
Query: 475 EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSS 528
G SS DS G S + ES + H SGR + SG S G G+ S
Sbjct: 849 ----GQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGS 898
Score = 43.1 bits (100), Expect = 7e-04
Identities = 55/215 (25%), Positives = 81/215 (37%), Gaps = 18/215 (8%)
Query: 321 GGNKGNMALAGT-ASMAPNSTKVAVAGAA-GKSSEHV-----SSASMSLSREGSVSLAIA 373
G + G+ + G S + S+ GA+ G+SS H SS S R+GS S
Sbjct: 1067 GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 1126
Query: 374 GVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRAL 433
G + ++ G + +SS SGQHG ++S G E + +
Sbjct: 1127 GHGQRGSGSRQSPSYGRHG----SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 1182
Query: 434 GRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGV 493
S +G +H G + Q S S + + G G+ SS H G
Sbjct: 1183 HGSGSGHSSGYGQH---GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS 1239
Query: 494 SHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSS 528
H+P SR H SG ++ G GR SS
Sbjct: 1240 GHSP----SRGRHGSGLGHSSSHGQHGSGSGRSSS 1270
Score = 42.7 bits (99), Expect = 0.001
Identities = 55/215 (25%), Positives = 81/215 (37%), Gaps = 18/215 (8%)
Query: 321 GGNKGNMALAGT-ASMAPNSTKVAVAGAA-GKSSEHV-----SSASMSLSREGSVSLAIA 373
G + G+ + G S + S+ GA+ G+SS H SS S R+GS S
Sbjct: 2007 GSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 2066
Query: 374 GVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRAL 433
G + ++ G + +SS SGQHG ++S G E + +
Sbjct: 2067 GHGQRGSGSRQSPSYGRHG----SGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQ 2122
Query: 434 GRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGV 493
S +G +H G + Q S S + + G G+ SS H G
Sbjct: 2123 HGSGSGHSSGYGQH---GSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGS 2179
Query: 494 SHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSS 528
H+P SR H SG ++ G GR SS
Sbjct: 2180 GHSP----SRGRHGSGSGHSSSHGQHGSGSGRSSS 2210
Score = 40.8 bits (94), Expect = 0.004
Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 9/134 (6%)
Query: 397 TRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQ 456
+R +SS S QHG +S+ G + G R+ +LG H +G+S +RG +
Sbjct: 962 SRSGQSSRSEQHGSSSGSSSSYG-QHGSGSRQ---SLGHGQHGSGSGQSPSPSRGRHGSG 1017
Query: 457 KSSSRSSFSHRANRDDKK-----EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511
S S +R+ E G G+ HR+S G S S + H S
Sbjct: 1018 SGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 1077
Query: 512 LWTTSSGSSKGLGR 525
++SG S G+
Sbjct: 1078 QHGSTSGQSSSCGQ 1091
Score = 40.0 bits (92), Expect = 0.006
Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 7/137 (5%)
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKE--GRERREKDRALGRSSHRRRTGESRHKTRG-- 451
S+ + S SGQ R S+ G G+ ++LG H +G+S +RG
Sbjct: 2365 SSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 2424
Query: 452 DKIAQKSSSRSSFSHRANRDDKK---EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKS 508
+ +SSS S + + + E G G+ HR+S G S S + H S
Sbjct: 2425 GSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2484
Query: 509 GRSLWTTSSGSSKGLGR 525
++SG S G+
Sbjct: 2485 THGQHGSTSGQSSSCGQ 2501
Score = 40.0 bits (92), Expect = 0.006
Identities = 54/215 (25%), Positives = 80/215 (37%), Gaps = 18/215 (8%)
Query: 321 GGNKGNMALAGT-ASMAPNSTKVAVAGAA-GKSSEHV-----SSASMSLSREGSVSLAIA 373
G + G+ + G S + S+ GA+ G+SS H SS S R+GS S
Sbjct: 2477 GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 2536
Query: 374 GVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRAL 433
G + ++ G + +SS SGQHG ++S G E + +
Sbjct: 2537 GHGQRGSGSRQSPSYGRHG----SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 2592
Query: 434 GRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGV 493
S +G +H G + Q S S + + G G+ SS H G
Sbjct: 2593 HGSGSGHSSGYGQH---GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS 2649
Query: 494 SHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSS 528
+P SR H SG ++ G GR SS
Sbjct: 2650 GQSP----SRGRHGSGLGHSSSHGQHGSGSGRSSS 2680
Score = 39.7 bits (91), Expect = 0.008
Identities = 57/219 (26%), Positives = 86/219 (39%), Gaps = 26/219 (11%)
Query: 321 GGNKGNMALAGT-ASMAPNSTKVAVAGAA-GKSSEHV-----SSASMSLSREGSVSLAIA 373
G + G+ + G S + S+ GA+ G+SS H SS S R+GS S
Sbjct: 1537 GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 1596
Query: 374 GVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRAL 433
G + ++ G + +SS SGQHG ++S G E + +
Sbjct: 1597 GHGQRGSGSRQSPSYGRHG----SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 1652
Query: 434 GRSSHRRRTGESRHKTRGDKIAQ----KSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDS 489
S +G +H +R + ++ SSSRSS + + G G+ SS H
Sbjct: 1653 HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRY-------GQHGSGSRQSSGHGRQ 1705
Query: 490 HKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSS 528
G +P SR H SG ++ G GR SS
Sbjct: 1706 GSGSGQSP----SRGRHGSGLGHSSSHGQHGSGSGRSSS 1740
Score = 38.9 bits (89), Expect = 0.013
Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 9/134 (6%)
Query: 397 TRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQ 456
+R +SS QHG +S+ G + G R+ +LG H +G+S +RG +
Sbjct: 1902 SRSGQSSRGEQHGSSSGSSSSYG-QHGSGSRQ---SLGHGQHGSGSGQSPSPSRGRHGSG 1957
Query: 457 KSSSRS-----SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511
S S S S ++ E G G+ HR+S G S S + H S
Sbjct: 1958 SGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 2017
Query: 512 LWTTSSGSSKGLGR 525
++SG S G+
Sbjct: 2018 QHGSASGQSSSCGQ 2031
Score = 38.5 bits (88), Expect = 0.018
Identities = 62/277 (22%), Positives = 98/277 (35%), Gaps = 25/277 (9%)
Query: 274 GIKEAAAAGAAAGAATGTVAGAL-SVAAANSAPGQVSA-----AIAGAATIDAGGNKGNM 327
G E+ + ++A + G+ +G S S GQ S + G ++ G+
Sbjct: 1285 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSS 1344
Query: 328 ALAGTASMAPNSTKVAVAGAAGKSSEHVSSA---------SMSLSREGSVSLAIAGV--- 375
+G S + G G S H SS S S R GS S +G
Sbjct: 1345 QSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1404
Query: 376 VLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKE--GRERREKDRAL 433
+S ++ + S+ + S SGQ R S+ G G+ ++L
Sbjct: 1405 ESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSL 1464
Query: 434 GRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSR-----HRD 488
G H +G+S +RG + S S + + +G GSS HR+
Sbjct: 1465 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRE 1524
Query: 489 SHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGR 525
S G S S + H S ++SG S G+
Sbjct: 1525 SRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQ 1561
Score = 38.1 bits (87), Expect = 0.023
Identities = 38/146 (26%), Positives = 55/146 (37%), Gaps = 23/146 (15%)
Query: 401 KSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESR-HKTRGDKIAQKSS 459
+SS SG+HG Q+S G K ++ G + H +G S ++ G + Q S
Sbjct: 915 RSSSSGRHGSGSGQSSGFGHKSS-----SGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 969
Query: 460 SRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSL------- 512
S S + + G G+ S H G +P R SG+S
Sbjct: 970 SEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRS 1029
Query: 513 ---WTTS-------SGSSKGLGRVSS 528
W++S SG S GLG S
Sbjct: 1030 GSGWSSSRGPYESGSGHSSGLGHRES 1055
Score = 37.0 bits (84), Expect = 0.051
Identities = 44/186 (23%), Positives = 68/186 (36%), Gaps = 20/186 (10%)
Query: 345 AGAAGKSSEHVSSA--SMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKS 402
+G + + H SS+ S S + GS S G + ++ G + S
Sbjct: 264 SGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHG----SGSGHS 319
Query: 403 SLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRS 462
S GQHG + + + G E + S + +G S+H + S S
Sbjct: 320 SSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGS--------GSGHS 371
Query: 463 SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKG 522
S + + G GSS + S G ES + H SGR ++ SG S G
Sbjct: 372 SSQGQHGSTSGQASSSGQHGSSSRQSSSYG------QHESASRHSSGRGQHSSGSGQSPG 425
Query: 523 LGRVSS 528
G+ S
Sbjct: 426 HGQRGS 431
Score = 36.6 bits (83), Expect = 0.067
Identities = 48/204 (23%), Positives = 76/204 (37%), Gaps = 20/204 (9%)
Query: 330 AGTASMAPNSTKVAVAGAAGKSSEHVSSASMS--LSREGSVSLAIAGVVLTSRTAAEADM 387
+G+ + N T + +G + S+H SS+ S S+ GS S +G + ++
Sbjct: 210 SGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQS-- 267
Query: 388 DAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRH 447
+ G + SS GQHG Q+ G ++G R+ SH R S H
Sbjct: 268 --SRGERHRSSSGSSSSYGQHGSGSRQSLGHG-RQGSGSRQSP------SHVRHGSGSGH 318
Query: 448 KTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHK 507
+ + SS S H E G G +S G S S + H
Sbjct: 319 SSSHGQHGSGSSYSYSRGHY-------ESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHS 371
Query: 508 SGRSLWTTSSGSSKGLGRVSSFLR 531
S + ++SG + G+ S R
Sbjct: 372 SSQGQHGSTSGQASSSGQHGSSSR 395
Score = 36.6 bits (83), Expect = 0.067
Identities = 45/184 (24%), Positives = 66/184 (35%), Gaps = 16/184 (8%)
Query: 353 EHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRER 412
E S S S S+ GS S +G + ++ G + SS GQHG
Sbjct: 1171 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG----SSSGSSSHYGQHGSGS 1226
Query: 413 TQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDD 472
Q+S G R+ + R H G S + + +SSSR + R+
Sbjct: 1227 RQSSGHG----RQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSS 1282
Query: 473 ---KKEKGCGNPGSSRHRDSHKG-----VSHTPISKESRTSHKSGRSLWTTSSGSSKGLG 524
+ E G G+ + S G H S +S T + G S +SS +G G
Sbjct: 1283 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSG 1342
Query: 525 RVSS 528
S
Sbjct: 1343 SSQS 1346
Score = 36.6 bits (83), Expect = 0.067
Identities = 45/184 (24%), Positives = 66/184 (35%), Gaps = 16/184 (8%)
Query: 353 EHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRER 412
E S S S S+ GS S +G + ++ G + SS GQHG
Sbjct: 1641 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG----SSSRSSSRYGQHGSGS 1696
Query: 413 TQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDD 472
Q+S G R+ ++ R H G S + + +SSSR + R+
Sbjct: 1697 RQSSGHG----RQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSS 1752
Query: 473 ---KKEKGCGNPGSSRHRDSHKG-----VSHTPISKESRTSHKSGRSLWTTSSGSSKGLG 524
+ E G G+ + S G H S +S T + G S +SS G G
Sbjct: 1753 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSG 1812
Query: 525 RVSS 528
S
Sbjct: 1813 SSQS 1816
Score = 36.2 bits (82), Expect = 0.087
Identities = 45/184 (24%), Positives = 66/184 (35%), Gaps = 16/184 (8%)
Query: 353 EHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRER 412
E S S S S+ GS S +G + ++ G + SS GQHG
Sbjct: 2581 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG----SSSGSSSHYGQHGSGS 2636
Query: 413 TQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDD 472
Q+S G R+ ++ R H G S + + +SSSR + R
Sbjct: 2637 RQSSGHG----RQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSS 2692
Query: 473 ---KKEKGCGNPGSSRHRDSHKG-----VSHTPISKESRTSHKSGRSLWTTSSGSSKGLG 524
+ E G G+ + S G H S +S T + G S +SS +G G
Sbjct: 2693 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSG 2752
Query: 525 RVSS 528
S
Sbjct: 2753 SSQS 2756
Score = 35.8 bits (81), Expect = 0.11
Identities = 43/157 (27%), Positives = 63/157 (40%), Gaps = 33/157 (21%)
Query: 402 SSLSGQHGRERTQASAEGCKEGRERR-----EKDRALGRSS----HRRRTGESRHKTRGD 452
SS SG+HG Q+S G E + + G SS H R+G+S +RG+
Sbjct: 1385 SSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQS---SRGE 1441
Query: 453 KIAQKSSSRSSFSHRANRDDKK----EKGCGN-----PGSSRHRD-SHKGVSHTPISK-- 500
+ S S SS+ + + + G G+ P RH S + S++P
Sbjct: 1442 RHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS 1501
Query: 501 ---------ESRTSHKSGRSLWTTSSGSSKGLGRVSS 528
ES +SH SG + SG S G G+ S
Sbjct: 1502 GWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGS 1538
Score = 35.4 bits (80), Expect = 0.15
Identities = 56/238 (23%), Positives = 84/238 (35%), Gaps = 43/238 (18%)
Query: 321 GGNKGNMALAGT--ASMAPNSTKVAVAGAAGKSSEHV-----SSASMSLSREGSVSLAIA 373
G G+ G ++ +ST + G+SS H SS S S ++GS S
Sbjct: 1771 GSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS---- 1826
Query: 374 GVVLTSRTAAEADMDAAAGPPVSTRQSKS-----SLSGQHGRERTQASAEGCKEGRERRE 428
++ + + +G S Q S S SG+HG Q+S G E +
Sbjct: 1827 -----GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS 1881
Query: 429 KDRALGRSSHRRRTGESR-HKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHR 487
G + H +G S ++ G + Q S S + + G G+ S H
Sbjct: 1882 S----GYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHG 1937
Query: 488 DSHKGVSHTPISKESRTSHKSGRSL----------WTTS-------SGSSKGLGRVSS 528
G +P R SG+S W++S SG S GLG S
Sbjct: 1938 QHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRES 1995
Score = 34.7 bits (78), Expect = 0.25
Identities = 61/250 (24%), Positives = 94/250 (37%), Gaps = 54/250 (21%)
Query: 321 GGNKGNMALAGT--ASMAPNSTKVAVAGAAGKSSEHV-----SSASMSLSREGSVSLAIA 373
G G+ G ++ +ST + G+SS H SS S S ++GS S
Sbjct: 2241 GSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS---- 2296
Query: 374 GVVLTSRTAAEADMDAAAGPPVSTRQSKS-----SLSGQHGRERTQASAEGCKEGRERR- 427
++ + + +G S Q S S SG+HG Q+S G E +
Sbjct: 2297 -----GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS 2351
Query: 428 ----EKDRALGRSS----HRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKK----E 475
+ G SS H R+G+S +RG++ S S SS+ + + +
Sbjct: 2352 SGYTQHGSGSGHSSSYEQHGSRSGQS---SRGERHGSSSGSSSSYGQHGSGSRQSLGHGQ 2408
Query: 476 KGCGN-----PGSSRHRD-SHKGVSHTPISK-----------ESRTSHKSGRSLWTTSSG 518
G G+ P RH S + S++P ES + H SG + SG
Sbjct: 2409 HGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSG 2468
Query: 519 SSKGLGRVSS 528
S G G+ S
Sbjct: 2469 QSSGYGQHGS 2478
Score = 34.3 bits (77), Expect = 0.33
Identities = 46/181 (25%), Positives = 63/181 (34%), Gaps = 42/181 (23%)
Query: 345 AGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSL 404
+G A +H S + S+ GS S +++ + +G +SS
Sbjct: 811 SGQASGFGQHESGSGQGYSQHGSAS---------GHFSSQGRHGSTSG--------QSSS 853
Query: 405 SGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESR-HKTRGDKIAQKSSSRSS 463
SGQH Q+S+ G E A GR H +G+S H RG Q S
Sbjct: 854 SGQHDSSSGQSSSYGQHESASHH----ASGRGRHGSGSGQSPGHGQRGSGSGQSPSY--- 906
Query: 464 FSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHK--SGRSLWTTSSGSSK 521
G GS R S G + + S HK SG+S T GS
Sbjct: 907 ---------------GRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGS 951
Query: 522 G 522
G
Sbjct: 952 G 952
Score = 33.5 bits (75), Expect = 0.57
Identities = 51/211 (24%), Positives = 73/211 (34%), Gaps = 44/211 (20%)
Query: 345 AGAAGKSSEHVSSASMSL--SREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKS 402
AG++ +H S + SL SR GS S ++ + +RQS S
Sbjct: 511 AGSSSSYGQHGSGSRQSLGHSRHGSGS-------------GQSPSPSRGRHESGSRQSSS 557
Query: 403 SLSGQHGRERTQASAEGCKE---------GRERREKDRALGRSSHRRRTGESR-HKTRGD 452
G HG ++S+ G E G + ++ G H +G S H G
Sbjct: 558 Y--GPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGS 615
Query: 453 KIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPI---------SKESR 503
Q SS + + G G+ SSR+ G +P S
Sbjct: 616 TSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSY 675
Query: 504 TSHKSGRSLWTTS-------SGSSKGLGRVS 527
H SG S W++S SG S G G S
Sbjct: 676 GQHGSG-SGWSSSNGPHGSVSGQSSGFGHKS 705
Score = 29.6 bits (65), Expect = 8.2
Identities = 54/256 (21%), Positives = 89/256 (34%), Gaps = 12/256 (4%)
Query: 274 GIKEAAAAGAAAGAATGTVAGALSVAAAN-SAPGQVSA-----AIAGAATIDAGGNKGNM 327
G +E+ + ++ G+ +G S + SA GQ S+ A +G ++ G+
Sbjct: 1991 GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSS 2050
Query: 328 ALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADM 387
+G S + G G S S S G S + ++
Sbjct: 2051 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHH 2110
Query: 388 DAAAGPPVSTRQ-----SKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRT 442
++++G S Q SS GQHG R+ S+ G + G R S R++
Sbjct: 2111 ESSSGQSSSYSQHGSGSGHSSGYGQHG-SRSGQSSRGERHGSSSGSSSRYGQHGSGSRQS 2169
Query: 443 GESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKES 502
+ G + S S ++ + G G S +S G S ES
Sbjct: 2170 SGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHES 2229
Query: 503 RTSHKSGRSLWTTSSG 518
+ H S S + SG
Sbjct: 2230 GSGHSSAYSQHGSGSG 2245
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 45.4 bits (106), Expect = 1e-04
Identities = 45/173 (26%), Positives = 76/173 (43%), Gaps = 16/173 (9%)
Query: 350 KSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEA-----DMDAAAGPPVSTRQSKSSL 404
++S+H S S S SRE G SR+ ++ D ++ S +
Sbjct: 34 RASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEH 93
Query: 405 SGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRG---------DKIA 455
S GRER +S G ++ +R+E+ + GRS R R+ E RH++R +
Sbjct: 94 SSDKGRERLNSSENG-EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRER 152
Query: 456 QKSSSRSSFSHRA-NRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHK 507
+KS SRS ++ +R ++++ + SR R H+ S + SR K
Sbjct: 153 KKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKK 205
Score = 37.0 bits (84), Expect = 0.051
Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 28/151 (18%)
Query: 398 RQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGR-----------SSHRRR----- 441
R+ KS G+ R R+++ KEGR KD++ + SS + R
Sbjct: 50 RKRKSDNEGRKHRSRSRS-----KEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNS 104
Query: 442 --TGESRHKTRGDKIAQ-KSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPI 498
GE RHK + K ++ +S SRS R +R +E+ SR R+ K S +
Sbjct: 105 SENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRER---KKSRSRSRERKKSRSRSRE 161
Query: 499 SKESRT-SHKSGRSLWTTSSGSSKGLGRVSS 528
K+SR+ S + R + + S S+ R S
Sbjct: 162 RKKSRSRSRERKRRIRSRSRSRSRHRHRTRS 192
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 45.1 bits (105), Expect = 2e-04
Identities = 77/334 (23%), Positives = 128/334 (38%), Gaps = 57/334 (17%)
Query: 281 AGAAAGAATGT---VAGALSVAAANSAPGQVSAAIAGAATIDAG--GNKGNMALAGTASM 335
A ++AG G+ + A S + + GQ S+A+ D+G G+ G+ A
Sbjct: 700 ARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVR-----DSGHRGSSGSQATDSEGHS 754
Query: 336 APNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAA-AGPP 394
+ T+ +V+G S + R G S + T +++ GP
Sbjct: 755 EDSDTQ-SVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPS 813
Query: 395 VSTRQ----------SKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGE 444
RQ S+ S S Q G++ + + GR+ ++++ RS H +
Sbjct: 814 TGVRQGSHHEQARDNSRHSAS-QDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGH-SGSHH 871
Query: 445 SRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKE--- 501
S ++G A + S S + R R++++ + SRH H+ SH IS+
Sbjct: 872 SHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRH---HEASSHADISRHSQA 928
Query: 502 -------SRTSHKSGRSLW--TTSSGSSKGLGRVS-SFLRNVRANLTTK----------- 540
SRTS + G S+ + S G S+ R S S RN R + +
Sbjct: 929 GQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSH 988
Query: 541 -VVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQ 573
HG D + R + AET+ GGQ
Sbjct: 989 HEDRAGHGHSAD-----SSRQSGTPHAETSSGGQ 1017
Score = 44.3 bits (103), Expect = 3e-04
Identities = 52/234 (22%), Positives = 94/234 (40%), Gaps = 22/234 (9%)
Query: 276 KEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASM 335
+++ +A AG +TG G+ A +S+ + SA+ G TI G+ G+ G
Sbjct: 3718 EQSESAHGRAGPSTGGRQGSRHEQARDSS--RHSASQEGQDTIR--GHPGSRR--GGRQG 3771
Query: 336 APNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPV 395
+ + V +G +G H +S S + G +G SR +
Sbjct: 3772 SYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQ-----SGSRSASRETRNEEQSGDGSRHS 3826
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
+R ++S R E R RR+ G S + E+ + +
Sbjct: 3827 GSRHHEASTQADSSRHSQSGQGESAGSRRSRRQ-----GSSVSQDSDSEAYPED-----S 3876
Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSG 509
++ S +S +H + ++ G +PGSS HRD+ V +P+ +S T+ + G
Sbjct: 3877 ERRSESASRNHHGSSREQSRDGSRHPGSS-HRDTASHVQSSPVQSDSSTAKEHG 3929
Score = 39.3 bits (90), Expect = 0.010
Identities = 46/204 (22%), Positives = 73/204 (35%), Gaps = 19/204 (9%)
Query: 317 TIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSS---EHVSSASMSLSREGSVSLAIA 373
T G + + +G+ S + + +G + S H +S +SR S A+
Sbjct: 2819 TTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRH---SQAVQ 2875
Query: 374 GVVLTSR------TAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERR 427
G SR ++ D D+ S R S S+ HG + Q +G + R +
Sbjct: 2876 GQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLR-DGSRHPRSHQ 2934
Query: 428 EKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHR 487
E G S+ R +RH S +++ SH R E+ + S
Sbjct: 2935 EDRAGHGHSADSSRQSGTRHTQTS------SGGQAASSHEQARSSAGERHGSHHQQSADS 2988
Query: 488 DSHKGVSHTPISKESRTSHKSGRS 511
H G+ H S R S G S
Sbjct: 2989 SRHSGIGHGQASSAVRDSGHRGYS 3012
Score = 38.9 bits (89), Expect = 0.013
Identities = 41/170 (24%), Positives = 57/170 (33%), Gaps = 21/170 (12%)
Query: 351 SSEHVSSASMSLSREGSVSLAIAGVVLTSR---TAAEADMDAAAGPPVSTRQSKSSLSGQ 407
S H +S+ SR V + TSR ++ D D+ S R S S+
Sbjct: 586 SRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNH 645
Query: 408 HGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHR 467
HG + Q S +G + R S H R G K + + SS
Sbjct: 646 HGSAQEQ-SRDGSRHPR-----------SHHEDRAGHGHSADSSRKSGTRHTQNSSSGQA 693
Query: 468 ANRDDKKEKGCGNPGSSRHR------DSHKGVSHTPISKESRTSHKSGRS 511
A+ ++ G SRH+ H G H S R S G S
Sbjct: 694 ASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSS 743
Score = 38.9 bits (89), Expect = 0.013
Identities = 50/196 (25%), Positives = 72/196 (36%), Gaps = 13/196 (6%)
Query: 332 TASMAPNSTKVAVAGAAGKSSEHVSSASMS-LSREGSVSLAIAGVVLTSR---TAAEADM 387
+AS K + G+ S H +AS + SR V + TSR ++ D
Sbjct: 1215 SASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDS 1274
Query: 388 DAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRH 447
D+ S R S S+ HG R Q S +G + +E + G S+ R + H
Sbjct: 1275 DSERHSDDSERLSGSASRNHHGSSREQ-SRDGSRHPGFHQEDRASHGHSADSSRQSGTHH 1333
Query: 448 KTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTS-H 506
S ++ SH R E+ S H G+ H S R S H
Sbjct: 1334 TE------SSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGH 1387
Query: 507 K-SGRSLWTTSSGSSK 521
+ S S T S G S+
Sbjct: 1388 RGSSGSQVTNSEGHSE 1403
Score = 38.1 bits (87), Expect = 0.023
Identities = 55/276 (19%), Positives = 105/276 (38%), Gaps = 24/276 (8%)
Query: 265 ELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIA--------GAA 316
E + T E A + +G A S + + GQ S+A++ G+
Sbjct: 362 ETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQ 421
Query: 317 TIDAGGNKGN-----MALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLA 371
D+ G+ N ++ G A + S + + G +G+ S S+ +S A
Sbjct: 422 ASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSA 481
Query: 372 IAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDR 431
G TS + A R S + Q G++ + + GR+ ++
Sbjct: 482 -HGRTGTSTGGRQGSHHEQA------RDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQ 534
Query: 432 ALGRSSHR-RRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSH 490
++ RS H + + R D +S SRS+ S + +++ G + GS H S
Sbjct: 535 SVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSA-SRQTRNEEQSGDGTRHSGSRHHEASS 593
Query: 491 KGVS--HTPISKESRTSHKSGRSLWTTSSGSSKGLG 524
+ S H+ + + + ++ R+ ++ S S G
Sbjct: 594 QADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQG 629
Score = 38.1 bits (87), Expect = 0.023
Identities = 83/351 (23%), Positives = 136/351 (38%), Gaps = 66/351 (18%)
Query: 269 EPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAP------GQVSAAIA-----GAAT 317
E ++GG +AA++ A ++ G G+ +A+S+ GQ S+A+ G++
Sbjct: 3280 ETSSGG--QAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSG 3337
Query: 318 IDAGGNKGNMALAGTASMAPNSTKVAVAGAAG--KSSEHVSSASMSLSREGSVSLAIAGV 375
A ++G+ + T S++ + G AG + S S+ S R G +G
Sbjct: 3338 SQASDSEGHSEESDTQSVSGH-------GQAGPHQQSHQESARDRSGGRSGR-----SGS 3385
Query: 376 VLTSRTAAEADMDAAAGPPVST-----------RQSKSSLSGQHGRERTQASAEGCKEGR 424
L + E A ST R S + Q G++ + + GR
Sbjct: 3386 FLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGR 3445
Query: 425 ERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKK---------- 474
+ ++++ RS H + S ++G A + S S + R R+D++
Sbjct: 3446 QGSHYEQSVDRSGH-SGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWS 3504
Query: 475 --EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLW--TTSSGSSKGLGRVS-SF 529
+ SSRH S +G S P RTS G S+ + S G S+ R S S
Sbjct: 3505 HHHEASTQADSSRHSQSGQGQSAGP-----RTSRNQGSSVSQDSDSQGHSEDSERWSGSA 3559
Query: 530 LRNVRANLTTKVVG-----TPHGRDVDVMAKMAE--RSTNVAIAETAEGGQ 573
RN R + + T H D AE R + AE + GGQ
Sbjct: 3560 SRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQ 3610
Score = 37.7 bits (86), Expect = 0.030
Identities = 59/265 (22%), Positives = 104/265 (39%), Gaps = 26/265 (9%)
Query: 269 EPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQ-VSAAIAGAATIDAG--GNKG 325
E ++GG +AA++ A ++ G G+ +A+S+ + A +A D+G G+ G
Sbjct: 1011 ETSSGG--QAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSG 1068
Query: 326 NMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEA 385
+ A + T+ +V+G G+ H S S +G + + E
Sbjct: 1069 SQASDSEGHSEESDTQ-SVSGH-GQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQ 1126
Query: 386 DMDAAAGPPVST-----------RQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALG 434
A ST R S + Q G++ +A + GR+ ++++
Sbjct: 1127 SESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVD 1186
Query: 435 RSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVS 494
RS H + S ++G A S S + R R DK+ SRH ++
Sbjct: 1187 RSGH-SGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWAD 1245
Query: 495 ---HTPISKE----SRTSHKSGRSL 512
H+ + +E SRTS G S+
Sbjct: 1246 SSRHSQVGQEQSSGSRTSRHQGSSV 1270
Score = 37.0 bits (84), Expect = 0.051
Identities = 39/164 (23%), Positives = 58/164 (35%), Gaps = 10/164 (6%)
Query: 351 SSEHVSSASMSLSREGSVSLAIAGVVLTSR---TAAEADMDAAAGPPVSTRQSKSSLSGQ 407
S H +S+ S V + TSR ++ D D+ S R S S+
Sbjct: 2532 SRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNH 2591
Query: 408 HGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHR 467
HG + Q +G + R +E G S+ R +RH S +++ SH
Sbjct: 2592 HGSAQEQLR-DGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTS------SGGQAASSHE 2644
Query: 468 ANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511
R E+ + S H G+ H S R S G S
Sbjct: 2645 QARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYS 2688
Score = 36.6 bits (83), Expect = 0.067
Identities = 38/172 (22%), Positives = 66/172 (38%), Gaps = 20/172 (11%)
Query: 346 GAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLS 405
G+A + S H S S +E S + A+ + S Q++SS
Sbjct: 1620 GSAREQSRHGSRNPRS-HQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPG 1678
Query: 406 GQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFS 465
+HG Q++ G RR+ +G S +R +G + G +++S ++S +
Sbjct: 1679 ERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGH--SEESDTQSVSA 1736
Query: 466 HRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSS 517
H G P H++S +G S S +SG L+ S+
Sbjct: 1737 H----------GQAGPHQQSHQESTRGQS-------GERSGRSGSFLYQVST 1771
Score = 36.6 bits (83), Expect = 0.067
Identities = 40/169 (23%), Positives = 58/169 (34%), Gaps = 20/169 (11%)
Query: 351 SSEHVSSASMSLSREGSVSLAIAGVVLTSR---TAAEADMDAAAGPPVSTRQSKSSLSGQ 407
S H +S+ SR V + TSR ++ D D+ S R+S S+
Sbjct: 2208 SHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNH 2267
Query: 408 HGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHR 467
HG + Q S +G + R S H R G + + SS
Sbjct: 2268 HGSAQEQ-SRDGSRHPR-----------SHHEDRAGHGHSAESSRQSGTHHAENSSGGQA 2315
Query: 468 ANRDDKKEKGCGNPGSSRHRDS-----HKGVSHTPISKESRTSHKSGRS 511
A+ ++ G S H+ S H G+ H S R S G S
Sbjct: 2316 ASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSS 2364
Score = 34.3 bits (77), Expect = 0.33
Identities = 41/167 (24%), Positives = 58/167 (34%), Gaps = 15/167 (8%)
Query: 351 SSEHVSSASMSLSREGSVSLAIAGVVLTSR---TAAEADMDAAAGPPVSTRQSKSSLSGQ 407
S H +S+ SR V + TSR ++ D D+ S R S S+ S
Sbjct: 1883 SRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSA-SRN 1941
Query: 408 HGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRH---KTRGDKIAQKSSSRSSF 464
H + S +G + E G S+ R +RH +RG + +RSS
Sbjct: 1942 HLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSA 2001
Query: 465 SHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511
R G + S H G+ H S R S G S
Sbjct: 2002 GER--------HGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYS 2040
Score = 34.3 bits (77), Expect = 0.33
Identities = 34/143 (23%), Positives = 49/143 (34%), Gaps = 15/143 (10%)
Query: 383 AEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRT 442
+++ +AGP S Q SS+S + +E R + A +S R
Sbjct: 3519 SQSGQGQSAGPRTSRNQG-SSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRH 3577
Query: 443 GESRHKTRGDKIAQKSSSRSSFSHRANRD---------DKKEKGCGNPGSSRHRDS---- 489
S H+ R SSR S +H A ++ G S H+ S
Sbjct: 3578 PTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSS 3637
Query: 490 -HKGVSHTPISKESRTSHKSGRS 511
H G+ H S R S G S
Sbjct: 3638 RHSGIGHGQASSAVRDSGHRGSS 3660
Score = 33.1 bits (74), Expect = 0.74
Identities = 46/208 (22%), Positives = 71/208 (34%), Gaps = 17/208 (8%)
Query: 317 TIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSS---EHVSSASMSLSREGSVSLAIA 373
T G + + +G+ S + + +G + + S H +S +SR S A+
Sbjct: 3143 TTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRH---SQAVQ 3199
Query: 374 GVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEG--RERREKDR 431
G SR + S Q S ER SA G +E+
Sbjct: 3200 GQSEGSRRSRRQGS--------SVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGS 3251
Query: 432 ALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHK 491
RS H R G R + + + SS A+ ++ G SRH+ S
Sbjct: 3252 RHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSAD 3311
Query: 492 GVSHTPISKESRTSHKSGRSLWTTSSGS 519
H+ I + +S W SSGS
Sbjct: 3312 SSRHSGIPRGQASSAVRDSRHW-GSSGS 3338
Score = 32.7 bits (73), Expect = 0.97
Identities = 24/112 (21%), Positives = 41/112 (36%), Gaps = 1/112 (0%)
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKE-GRERREKDRALGRSSHRRRTGESRHKTRGDKI 454
S Q++SS +HG SA+ + G + A+ S HR +G + G
Sbjct: 696 SHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSE 755
Query: 455 AQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSH 506
+ S S + ++ + R R S + K+S +SH
Sbjct: 756 DSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSH 807
Score = 32.7 bits (73), Expect = 0.97
Identities = 45/215 (20%), Positives = 78/215 (36%), Gaps = 17/215 (7%)
Query: 317 TIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVV 376
++D G+ G+ T+ ++++ G +G S ++ + SR+GS
Sbjct: 860 SVDRSGHSGSHHSHTTSQGRSDASR----GQSGSRSASRTTRNEEQSRDGSRHSGSRHHE 915
Query: 377 LTSRTA----AEADMDAAAGPPVSTRQ----SKSSLSGQHGRERTQASAEGCKEGRERRE 428
+S ++A + G S RQ S+ S S H + + S + R +
Sbjct: 916 ASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQ 975
Query: 429 KDRALG----RSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSS 484
+ G RS H R G + + SS A+ ++ G S
Sbjct: 976 EQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGS 1035
Query: 485 RHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGS 519
RH+ S H+ I + +S W SSGS
Sbjct: 1036 RHQQSADSSRHSGIPRRQASSAVRDSGHW-GSSGS 1069
Score = 32.3 bits (72), Expect = 1.3
Identities = 28/127 (22%), Positives = 50/127 (39%), Gaps = 4/127 (3%)
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
S Q++SS +HG Q++ G + A+ S HR +G + G +
Sbjct: 2318 SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGH--S 2375
Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTT 515
+ S ++S +H ++ G S R G +S ++ GR+ T
Sbjct: 2376 EDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRT--GT 2433
Query: 516 SSGSSKG 522
S+G +G
Sbjct: 2434 STGGRQG 2440
Score = 32.0 bits (71), Expect = 1.7
Identities = 38/145 (26%), Positives = 52/145 (35%), Gaps = 14/145 (9%)
Query: 390 AAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKT 449
+AG S RQ SS+S E +E E R A +S H R S +
Sbjct: 1581 SAGSKTSRRQG-SSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQED 1639
Query: 450 RGDKIAQKSSSRSSFSHRANRD------DKKEKGCGNPGSSRHRDSHKGVSHTPISKESR 503
R SSR S + A +E+ +PG RH H+ S +S
Sbjct: 1640 RASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPG-ERHGSRHQQ------SADSS 1692
Query: 504 TSHKSGRSLWTTSSGSSKGLGRVSS 528
T +GR ++ G S G S
Sbjct: 1693 TDSGTGRRQDSSVVGDSGNRGSSGS 1717
Score = 31.6 bits (70), Expect = 2.2
Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 19/123 (15%)
Query: 396 STRQSKSSLSGQHGRERTQASAEGC---KEGRERREKDRAL----------GRSSHRRRT 442
STR+ +SG R+ + +E +E R++ +L GRS R T
Sbjct: 88 STRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRET 147
Query: 443 GESRHKTRGDKIAQKSSS----RSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPI 498
G RH++ +K +K S + + KKEK ++R D+ K +S
Sbjct: 148 GGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEK--NKTENTRLGDNRKRLSERLE 205
Query: 499 SKE 501
KE
Sbjct: 206 EKE 208
Score = 31.6 bits (70), Expect = 2.2
Identities = 27/133 (20%), Positives = 46/133 (34%)
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
S Q++SS +HG Q++ G RR+ A+ S H +G + G
Sbjct: 1021 SHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEE 1080
Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTT 515
+ S S ++ + R S + ++S ++H R+
Sbjct: 1081 SDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGR 1140
Query: 516 SSGSSKGLGRVSS 528
GS R SS
Sbjct: 1141 RQGSHHEQARDSS 1153
Score = 31.6 bits (70), Expect = 2.2
Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 12/99 (12%)
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
S Q++SS +HG Q++ G R+ A+ S HR +G + G +
Sbjct: 1345 SHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGH--S 1402
Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVS 494
+ S ++S +H G P H++S +G S
Sbjct: 1403 EDSDTQSVSAH----------GQAGPHQQSHKESARGQS 1431
Score = 31.2 bits (69), Expect = 2.8
Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 22/116 (18%)
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
S Q++SS +HG Q++ G + A+ S HR +G + G +
Sbjct: 3614 SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGH--S 3671
Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511
+ S ++S +H G P H++S +G R++ +SGRS
Sbjct: 3672 EDSDTQSVSAH----------GQAGPHQQSHQESTRG----------RSAGRSGRS 3707
Score = 30.8 bits (68), Expect = 3.7
Identities = 33/177 (18%), Positives = 63/177 (35%), Gaps = 6/177 (3%)
Query: 317 TIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSS---EHVSSASMSLSREGSVSLAIA 373
T G + + +G+ S + + +G + S H +S SR +
Sbjct: 3791 TTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGES 3850
Query: 374 GVVLTSR---TAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKD 430
SR ++ D D+ A P S R+S+S+ HG R Q+ G R+
Sbjct: 3851 AGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTA 3910
Query: 431 RALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHR 487
+ S + + ++ ++Q S+ S R + + G+ R +
Sbjct: 3911 SHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQK 3967
Score = 30.0 bits (66), Expect = 6.3
Identities = 28/122 (22%), Positives = 44/122 (36%), Gaps = 19/122 (15%)
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
S Q++SS +HG Q++ G + A+ S HR +G G
Sbjct: 2642 SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEG---- 2697
Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTT 515
H + D + G GS H+ SH+ + + TS SG L+
Sbjct: 2698 ----------HSEDSDTQSVSAHGQAGS--HQQSHQ---ESARGRSGETSGHSGSFLYQV 2742
Query: 516 SS 517
S+
Sbjct: 2743 ST 2744
Score = 30.0 bits (66), Expect = 6.3
Identities = 28/122 (22%), Positives = 44/122 (36%), Gaps = 19/122 (15%)
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
S Q++SS +HG Q++ G + A+ S HR +G G
Sbjct: 2966 SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEG---- 3021
Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTT 515
H + D + G GS H+ SH+ + + TS SG L+
Sbjct: 3022 ----------HSEDSDTQSVSAHGQAGS--HQQSHQ---ESARGRSGETSGHSGSFLYQV 3066
Query: 516 SS 517
S+
Sbjct: 3067 ST 3068
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 43.1 bits (100), Expect = 7e-04
Identities = 61/237 (25%), Positives = 96/237 (40%), Gaps = 33/237 (13%)
Query: 279 AAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPN 338
A A A AG G G L + G V A GA T+D +A G N
Sbjct: 126 APANAVAGLLPG--GGLLPTPNPLTQIGAVPLAALGAPTLDPA-----LAALGLPGANLN 178
Query: 339 STKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTR 398
S +A A + + +S+ L+ V+ + L S T+++ +A R
Sbjct: 179 SQSLA----ADQLLKLMSTVDPKLNH---VAAGLVSPSLKSDTSSKEIEEAMK----RVR 227
Query: 399 QSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKS 458
+++S +S A+ E K+ E+R R+ RS RR SRH+ + ++S
Sbjct: 228 EAQSLIS---------AAIEPDKK-EEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRS 277
Query: 459 SSRS-----SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR 510
S+S S S R R +E+G + +S+ RD K SK S+ + R
Sbjct: 278 HSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTAR 334
Score = 31.6 bits (70), Expect = 2.2
Identities = 30/136 (22%), Positives = 52/136 (38%), Gaps = 19/136 (13%)
Query: 396 STRQSKSSLSGQ-HGRER------TQASAEGCKEGRERRE------------KDRALGRS 436
S R+SKS + H RER T + + KE +E++ + R+ R
Sbjct: 283 SRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRE 342
Query: 437 SHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHT 496
RRR+ + + ++ SRS R ++ KK+K R R + K
Sbjct: 343 RRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSK 402
Query: 497 PISKESRTSHKSGRSL 512
K+ +S + +
Sbjct: 403 DKEKDRERKSESDKDV 418
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 43.1 bits (100), Expect = 7e-04
Identities = 38/159 (23%), Positives = 67/159 (42%), Gaps = 20/159 (12%)
Query: 331 GTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAA 390
G A + ++ + ++ SS SS+S S S GS S + + +S T+ + D++
Sbjct: 564 GRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSS-SRSSSSSSSSTSGSSSRDSS 622
Query: 391 AGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTR 450
+ S+ S H R+R + +R+ +D + SH+ G S T+
Sbjct: 623 SSTSSSSESRSRSRGRGHNRDRKH------RRSVDRKRRDTSGLERSHKSSKGGSSRDTK 676
Query: 451 GDK-------------IAQKSSSRSSFSHRANRDDKKEK 476
G K + +S RSS S R + D+K+K
Sbjct: 677 GSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDK 715
Score = 39.3 bits (90), Expect = 0.010
Identities = 44/157 (28%), Positives = 62/157 (39%), Gaps = 21/157 (13%)
Query: 356 SSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQA 415
+ S S SR S S + + S T++ + +++G S S SS S R +
Sbjct: 568 NKTSKSRSRSSSSSSSSS-----SSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSS 622
Query: 416 SAEGCKEGRERREKDRALGRS-SHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKK 474
S+ R + R R HRR R T G + + KSS S +RD K
Sbjct: 623 SSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGS-----SRDTKG 677
Query: 475 EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511
K N S R R IS+ SR+ +S RS
Sbjct: 678 SKD-KNSRSDRKRS---------ISESSRSGKRSSRS 704
Score = 31.2 bits (69), Expect = 2.8
Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 13/116 (11%)
Query: 425 ERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSS 484
E + K + RS R R S+ ++R + SSS +S S ++ + GSS
Sbjct: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSS---------SSSGSS 601
Query: 485 RHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTK 540
R S S T S +S S S ++S S+ GR + R R ++ K
Sbjct: 602 SSRSSSSSSSSTSGS----SSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRK 653
Score = 30.0 bits (66), Expect = 6.3
Identities = 29/121 (23%), Positives = 45/121 (37%), Gaps = 6/121 (4%)
Query: 408 HGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQ--KSSSRSSFS 465
H +++ GR R + ++ RSS + S + + SSSRSS S
Sbjct: 549 HPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSS 608
Query: 466 HRANR--DDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR--SLWTTSSGSSK 521
++ ++ SS R +G H K R+ + R S S SSK
Sbjct: 609 SSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSK 668
Query: 522 G 522
G
Sbjct: 669 G 669
>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
Length = 450
Score = 42.0 bits (97), Expect = 0.002
Identities = 40/133 (30%), Positives = 59/133 (44%), Gaps = 12/133 (9%)
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
S+ S SS S E + S KE + +R+K + S H E + K++ K+
Sbjct: 260 SSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLH 319
Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGV--SHTPISKESRT-SHKSGRSL 512
++ SS SH NR+ KEK P +H S + SH+ K+SRT H +
Sbjct: 320 EELSS----SHH-NREKAKEK----PRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRG 370
Query: 513 WTTSSGSSKGLGR 525
GSS+ GR
Sbjct: 371 SERKEGSSRSHGR 383
Score = 35.0 bits (79), Expect = 0.19
Identities = 39/174 (22%), Positives = 69/174 (39%), Gaps = 27/174 (15%)
Query: 350 KSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHG 409
K +H SS+S S S S S TS +++E++ + ++ K+ SG +
Sbjct: 251 KHKKHKSSSSSSSSSSSSSSTE------TSESSSESESNNKEKKIQRKKRKKNKCSGHNN 304
Query: 410 --------------RERTQASAEGCKEGRER-----REKDRALGRSSHRRRTGESR-HKT 449
E +S ++ +E+ E R + SH +SR HK
Sbjct: 305 SDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKH 364
Query: 450 RGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESR 503
+K + SS SH ++ + +PGS + R++ K P ++SR
Sbjct: 365 SPEKRGSERKEGSSRSHGREERSRRSRS-RSPGSYKQRETRKRAQRNPGEEQSR 417
Score = 33.9 bits (76), Expect = 0.43
Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 2/106 (1%)
Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERRE-KDRALGRSSHRRRTGESRHKTRGDKI 454
S SK S S + RT + K G ER+E R+ GR RR+ + +
Sbjct: 344 SREDSKWSHSDSDKKSRTHKHSPE-KRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRE 402
Query: 455 AQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISK 500
+K + R+ ++ R+D + G + H G +HT +++
Sbjct: 403 TRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHTKVTQ 448
>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
Length = 221
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 3/88 (3%)
Query: 424 RERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGS 483
R RR + R+ RS R R+ SR K+R +S SRS+ R+ R K + +
Sbjct: 124 RRRRSRSRSRSRSRSRSRSRYSRSKSRS---RTRSRSRSTSKSRSARRSKSKSSSVSRSR 180
Query: 484 SRHRDSHKGVSHTPISKESRTSHKSGRS 511
SR R + S P+SK S +S
Sbjct: 181 SRSRSRSRSRSPPPVSKRESKSRSRSKS 208
>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 41.6 bits (96), Expect = 0.002
Identities = 54/285 (18%), Positives = 102/285 (35%), Gaps = 7/285 (2%)
Query: 263 STELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGG 322
S E +E + + AG+ T TV+ A S S G + ++ +
Sbjct: 957 SAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016
Query: 323 NKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTA 382
+ T++ +T V AG+ + S + + S EGS + ++ + TA
Sbjct: 1017 STTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTA 1076
Query: 383 AEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRT 442
+ AD++ VST S ++ + G E T G K E A S+ T
Sbjct: 1077 STADLETTT---VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133
Query: 443 GESRHKTRGDKIAQ--KSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISK 500
+ T G ++ + S ++ + G+ ++ + + + +
Sbjct: 1134 --TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS 1191
Query: 501 ESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTKVVGTP 545
E+ T+ +G T S+ S+ +S A T TP
Sbjct: 1192 ETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1236
Score = 40.4 bits (93), Expect = 0.005
Identities = 41/180 (22%), Positives = 76/180 (42%), Gaps = 17/180 (9%)
Query: 252 TNVLNASIPKTSTELAEE---PATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQV 308
T ++ AS T++ E P+ G + + + + T + AG+ + +++ G
Sbjct: 27 TILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTT 86
Query: 309 SAAIAGAATI--DAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREG 366
+A++AG+ T AG +++ GT +T V+ G+ ++ SS + S G
Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGT-----ETTMVSAMGSETTTNSTTSSETTVTSTAG 141
Query: 367 SVSLAIAGVVLTSRTAAEADMDAAAG-------PPVSTRQSKSSLSGQHGRERTQASAEG 419
S + ++ V + TA AD + A V T S++ G E T S G
Sbjct: 142 SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAG 201
Score = 36.6 bits (83), Expect = 0.067
Identities = 32/149 (21%), Positives = 55/149 (36%), Gaps = 5/149 (3%)
Query: 271 ATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALA 330
+T G + + + T + G + + + + GA T A
Sbjct: 527 STEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586
Query: 331 GTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAA 390
TA +T V+ A + ++ S + S S GS + + TS A + +
Sbjct: 587 STAGS--ETTTVSTADSENTTASTADSETTSASTTGSETTTAS---TTSSETTTASTEGS 641
Query: 391 AGPPVSTRQSKSSLSGQHGRERTQASAEG 419
VST S++++ G ERT S EG
Sbjct: 642 ETTTVSTTDSETTMVSTTGSERTITSTEG 670
Score = 36.6 bits (83), Expect = 0.067
Identities = 45/193 (23%), Positives = 78/193 (40%), Gaps = 12/193 (6%)
Query: 234 TSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVA 293
TSA+ G E + ASI + T +A +T G + + A++ T
Sbjct: 753 TSASTTGSETTTASTTSSETTM-ASIMGSETTMA---STIGSETTKVSTASSKMTTVFTE 808
Query: 294 GALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGA----AG 349
+ + A+ +A + + AG+ TI A G+ T++ +T + G+ A
Sbjct: 809 NSETTIASTTASETTTVSTAGSETIPAS-TAGSETTTTTSTEGSETTTASTEGSETTTAS 867
Query: 350 KSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPP---VSTRQSKSSLSG 406
S ++A+ S + S + TS +E + G VST S+++ +
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 407 QHGRERTQASAEG 419
G E T AS EG
Sbjct: 928 TEGSETTTASTEG 940
Score = 36.6 bits (83), Expect = 0.067
Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 21/130 (16%)
Query: 262 TSTELAEEP--ATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGA--AT 317
TSTE +E +T G + A+ A + T + AG+ + A+ S +A G+ +T
Sbjct: 1176 TSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETST 1235
Query: 318 IDAGGNKGNMA--------LAGTASMAPNSTKVA---------VAGAAGKSSEHVSSASM 360
+ G++ N A +A TAS+ P +T + A A +S VSS +
Sbjct: 1236 PSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTF 1295
Query: 361 SLSREGSVSL 370
L++ VS+
Sbjct: 1296 VLTKATDVSI 1305
Score = 32.7 bits (73), Expect = 0.97
Identities = 34/156 (21%), Positives = 61/156 (39%), Gaps = 12/156 (7%)
Query: 272 TGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAG 331
T + AA+ + T AG+ ++ + + + + AG+ T A
Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218
Query: 332 TA--------SMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAA 383
TA +M +TKV+ AG+ S S + + + + + A T+ TA+
Sbjct: 219 TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT-TAS 277
Query: 384 EADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEG 419
+ A ST S+ +++ G E T AS G
Sbjct: 278 TTGFETTA---ASTTGSEPTMASTMGSETTMASTIG 310
Score = 32.3 bits (72), Expect = 1.3
Identities = 43/198 (21%), Positives = 76/198 (38%), Gaps = 21/198 (10%)
Query: 227 VSEVCGATSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAG 286
VS T+ A G + F T V + T A + G + + +
Sbjct: 1126 VSTTSSETTTASTTGSEMTTVF---TTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE 1182
Query: 287 AATGTVAGALSVAAANSAPGQVSAAIAGAATIDA--GGNKGNMAL-----AGTASMAPNS 339
T + AG+ + A+ + +A+ AG+ T A G++ N A T S A +
Sbjct: 1183 TTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1242
Query: 340 TKVA-VAGA----AGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADM------D 388
T A + G+ A +S ++ S++ S +VS+ +G S T + D
Sbjct: 1243 TNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATD 1302
Query: 389 AAAGPPVSTRQSKSSLSG 406
+ P +T S + +G
Sbjct: 1303 VSIQPITNTPMSGTRTTG 1320
>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 41.6 bits (96), Expect = 0.002
Identities = 54/285 (18%), Positives = 102/285 (35%), Gaps = 7/285 (2%)
Query: 263 STELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGG 322
S E +E + + AG+ T TV+ A S S G + ++ +
Sbjct: 957 SAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016
Query: 323 NKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTA 382
+ T++ +T V AG+ + S + + S EGS + ++ + TA
Sbjct: 1017 STTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTA 1076
Query: 383 AEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRT 442
+ AD++ VST S ++ + G E T G K E A S+ T
Sbjct: 1077 STADLETTT---VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133
Query: 443 GESRHKTRGDKIAQ--KSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISK 500
+ T G ++ + S ++ + G+ ++ + + + +
Sbjct: 1134 --TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS 1191
Query: 501 ESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTKVVGTP 545
E+ T+ +G T S+ S+ +S A T TP
Sbjct: 1192 ETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1236
Score = 40.4 bits (93), Expect = 0.005
Identities = 41/180 (22%), Positives = 76/180 (42%), Gaps = 17/180 (9%)
Query: 252 TNVLNASIPKTSTELAEE---PATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQV 308
T ++ AS T++ E P+ G + + + + T + AG+ + +++ G
Sbjct: 27 TILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTT 86
Query: 309 SAAIAGAATI--DAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREG 366
+A++AG+ T AG +++ GT +T V+ G+ ++ SS + S G
Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGT-----ETTMVSAMGSETTTNSTTSSETTVTSTAG 141
Query: 367 SVSLAIAGVVLTSRTAAEADMDAAAG-------PPVSTRQSKSSLSGQHGRERTQASAEG 419
S + ++ V + TA AD + A V T S++ G E T S G
Sbjct: 142 SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAG 201
Score = 36.6 bits (83), Expect = 0.067
Identities = 32/149 (21%), Positives = 55/149 (36%), Gaps = 5/149 (3%)
Query: 271 ATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALA 330
+T G + + + T + G + + + + GA T A
Sbjct: 527 STEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586
Query: 331 GTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAA 390
TA +T V+ A + ++ S + S S GS + + TS A + +
Sbjct: 587 STAGS--ETTTVSTADSENTTASTADSETTSASTTGSETTTAS---TTSSETTTASTEGS 641
Query: 391 AGPPVSTRQSKSSLSGQHGRERTQASAEG 419
VST S++++ G ERT S EG
Sbjct: 642 ETTTVSTTDSETTMVSTTGSERTITSTEG 670
Score = 36.6 bits (83), Expect = 0.067
Identities = 45/193 (23%), Positives = 78/193 (40%), Gaps = 12/193 (6%)
Query: 234 TSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVA 293
TSA+ G E + ASI + T +A +T G + + A++ T
Sbjct: 753 TSASTTGSETTTASTTSSETTM-ASIMGSETTMA---STIGSETTKVSTASSKMTTVFTE 808
Query: 294 GALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGA----AG 349
+ + A+ +A + + AG+ TI A G+ T++ +T + G+ A
Sbjct: 809 NSETTIASTTASETTTVSTAGSETIPAS-TAGSETTTTTSTEGSETTTASTEGSETTTAS 867
Query: 350 KSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPP---VSTRQSKSSLSG 406
S ++A+ S + S + TS +E + G VST S+++ +
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 407 QHGRERTQASAEG 419
G E T AS EG
Sbjct: 928 TEGSETTTASTEG 940
Score = 36.6 bits (83), Expect = 0.067
Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 21/130 (16%)
Query: 262 TSTELAEEP--ATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGA--AT 317
TSTE +E +T G + A+ A + T + AG+ + A+ S +A G+ +T
Sbjct: 1176 TSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETST 1235
Query: 318 IDAGGNKGNMA--------LAGTASMAPNSTKVA---------VAGAAGKSSEHVSSASM 360
+ G++ N A +A TAS+ P +T + A A +S VSS +
Sbjct: 1236 PSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTF 1295
Query: 361 SLSREGSVSL 370
L++ VS+
Sbjct: 1296 VLTKATDVSI 1305
Score = 32.7 bits (73), Expect = 0.97
Identities = 34/156 (21%), Positives = 61/156 (39%), Gaps = 12/156 (7%)
Query: 272 TGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAG 331
T + AA+ + T AG+ ++ + + + + AG+ T A
Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218
Query: 332 TA--------SMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAA 383
TA +M +TKV+ AG+ S S + + + + + A T+ TA+
Sbjct: 219 TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT-TAS 277
Query: 384 EADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEG 419
+ A ST S+ +++ G E T AS G
Sbjct: 278 TTGFETTA---ASTTGSEPTMASTMGSETTMASTIG 310
Score = 32.3 bits (72), Expect = 1.3
Identities = 43/198 (21%), Positives = 76/198 (38%), Gaps = 21/198 (10%)
Query: 227 VSEVCGATSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAG 286
VS T+ A G + F T V + T A + G + + +
Sbjct: 1126 VSTTSSETTTASTTGSEMTTVF---TTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE 1182
Query: 287 AATGTVAGALSVAAANSAPGQVSAAIAGAATIDA--GGNKGNMAL-----AGTASMAPNS 339
T + AG+ + A+ + +A+ AG+ T A G++ N A T S A +
Sbjct: 1183 TTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1242
Query: 340 TKVA-VAGA----AGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADM------D 388
T A + G+ A +S ++ S++ S +VS+ +G S T + D
Sbjct: 1243 TNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATD 1302
Query: 389 AAAGPPVSTRQSKSSLSG 406
+ P +T S + +G
Sbjct: 1303 VSIQPITNTPMSGTRTTG 1320
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.126 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,776,148
Number of Sequences: 37866
Number of extensions: 888142
Number of successful extensions: 6213
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 148
Number of HSP's successfully gapped in prelim test: 333
Number of HSP's that attempted gapping in prelim test: 4164
Number of HSP's gapped (non-prelim): 1617
length of query: 594
length of database: 18,247,518
effective HSP length: 108
effective length of query: 486
effective length of database: 14,157,990
effective search space: 6880783140
effective search space used: 6880783140
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.