Guide to the Human Genome
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Search of human proteins with 23957696

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23957696 hypothetical protein LOC149647 [Homo sapiens]
         (594 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23957696 hypothetical protein LOC149647 [Homo sapiens]            1163   0.0  
gi|222418633 family with sequence similarity 71, member B [Homo ...   503   e-142
gi|23503301 hypothetical protein LOC196472 [Homo sapiens]             261   1e-69
gi|89363024 hypothetical protein LOC161142 [Homo sapiens]             107   4e-23
gi|76253859 hypothetical protein LOC112703 [Homo sapiens]             106   5e-23
gi|223972704 hypothetical protein LOC284418 [Homo sapiens]             92   1e-18
gi|14211935 testes development-related NYD-SP18 [Homo sapiens]         85   2e-16
gi|193083150 hypothetical protein LOC346653 isoform b [Homo sapi...    73   8e-13
gi|149192824 hypothetical protein LOC346653 isoform a [Homo sapi...    65   2e-10
gi|161016767 mucin 21 [Homo sapiens]                                   55   1e-07
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           53   7e-07
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           53   7e-07
gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]             52   2e-06
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]            50   4e-06
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           49   1e-05
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]     48   2e-05
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]     48   2e-05
gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens]             47   4e-05
gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens]             47   4e-05
gi|24497554 homeobox A13 [Homo sapiens]                                47   6e-05
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi...    46   8e-05
gi|57864582 hornerin [Homo sapiens]                                    46   1e-04
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    45   1e-04
gi|60097902 filaggrin [Homo sapiens]                                   45   2e-04
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     43   7e-04
gi|33356174 pinin, desmosome associated protein [Homo sapiens]         43   7e-04
gi|40068059 CBF1 interacting corepressor [Homo sapiens]                42   0.002
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]     42   0.002
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            42   0.002
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            42   0.002

>gi|23957696 hypothetical protein LOC149647 [Homo sapiens]
          Length = 594

 Score = 1163 bits (3009), Expect = 0.0
 Identities = 594/594 (100%), Positives = 594/594 (100%)

Query: 1   MNADFLLPYYTAQSGSSMSMFDTTMGKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVI 60
           MNADFLLPYYTAQSGSSMSMFDTTMGKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVI
Sbjct: 1   MNADFLLPYYTAQSGSSMSMFDTTMGKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVI 60

Query: 61  DVHNRVRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTR 120
           DVHNRVRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTR
Sbjct: 61  DVHNRVRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTR 120

Query: 121 LLPLRFVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPMES 180
           LLPLRFVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPMES
Sbjct: 121 LLPLRFVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPMES 180

Query: 181 NSSTCGIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAYAG 240
           NSSTCGIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAYAG
Sbjct: 181 NSSTCGIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAYAG 240

Query: 241 GEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAA 300
           GEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAA
Sbjct: 241 GEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAA 300

Query: 301 ANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASM 360
           ANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASM
Sbjct: 301 ANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASM 360

Query: 361 SLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGC 420
           SLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGC
Sbjct: 361 SLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGC 420

Query: 421 KEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGN 480
           KEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGN
Sbjct: 421 KEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGN 480

Query: 481 PGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTK 540
           PGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTK
Sbjct: 481 PGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTK 540

Query: 541 VVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGLEMVGSMTPDIMETVTFEAH 594
           VVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGLEMVGSMTPDIMETVTFEAH
Sbjct: 541 VVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGLEMVGSMTPDIMETVTFEAH 594


>gi|222418633 family with sequence similarity 71, member B [Homo
           sapiens]
          Length = 605

 Score =  503 bits (1295), Expect = e-142
 Identities = 300/612 (49%), Positives = 396/612 (64%), Gaps = 31/612 (5%)

Query: 1   MNADFLLPYYTAQSGSSMSMFDTTMGKLQRQLY-KGEYDIFKYAPIFESDFIQITKRGEV 59
           M+ +  LPYYTA S SSMS F T+MG LQRQLY +GEY+IFKYAP+FES+FIQI K+GEV
Sbjct: 1   MSNESCLPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEV 60

Query: 60  IDVHNRVRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELT 119
           IDVHNRVRMVT+GI  TSPILPLPDVM+LA+P   CE++   G+  K + R+  K LELT
Sbjct: 61  IDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELT 120

Query: 120 RLLPLRFVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPME 179
           RLLPL+FV+IS+ DHEKQQLRLK ATGR+ YLQLCP+ DTR+DLF YWEKL+YLLRPP+E
Sbjct: 121 RLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVE 180

Query: 180 SNSSTCGIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAYA 239
           S  ST  + + D        ED +SL A  L  +GDQ +     L+   +V  ATS+AYA
Sbjct: 181 SYCSTPTLLSGDAP-----PEDNKSLVAAELHREGDQSET---GLYKPCDVSAATSSAYA 232

Query: 240 GGEGLQNDFNKPTNVLNASIPKTSTELAEE----PATGGIKEAAAAG------AAAGAAT 289
           GGEG+Q+  +      +A+ P TST  A E       GG+  A  A       A AGAA 
Sbjct: 233 GGEGIQHASH---GTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAM 289

Query: 290 GTVAGALSVAAANSA-PGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAA 348
               GA+S+A   SA PGQV+ A+AGAA  + G N+ + ++AG A+++     +A+ GAA
Sbjct: 290 SPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAA 349

Query: 349 GKSSEHVSSA---SMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLS 405
             S E  S++   + SLS++ S+S A AG + TS+ AAE     A GP +ST QS+  +S
Sbjct: 350 STSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMS 409

Query: 406 GQHGRER-TQASAEGCKEGRERRE-KDRALGR-SSHRRRTGESRHKTRGDKIAQKSSSRS 462
            + G ++ +Q SAE   E +ERRE KDR   R SSH R+ GES  +  GDK  + SS RS
Sbjct: 410 ERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRS 469

Query: 463 SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGS-SK 521
           +  H+  RDDKKEKG  N    RH  S K  +H+   KESRT+ + G++   +S+G+  K
Sbjct: 470 ASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQK 529

Query: 522 GLGRVSSFLRNVRANLTTKVVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGLEMV-GS 580
              ++SSFLR++RA   +K   T H R+VD++AKM E+    A  E A+GGQ LEM+ G+
Sbjct: 530 KASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELEMISGT 589

Query: 581 MTPDIMETVTFE 592
           MT +  E + FE
Sbjct: 590 MTSEKTEMIVFE 601


>gi|23503301 hypothetical protein LOC196472 [Homo sapiens]
          Length = 241

 Score =  261 bits (668), Expect = 1e-69
 Identities = 136/233 (58%), Positives = 172/233 (73%), Gaps = 1/233 (0%)

Query: 6   LLPYYTAQSGSSMSMFDTTMGKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNR 65
           +LPYYTAQS  +M MF+T+MGKLQRQLYKGEY IF+YAP+FESDFIQI+KRGEVIDVHNR
Sbjct: 6   MLPYYTAQSSPAMGMFNTSMGKLQRQLYKGEYTIFRYAPMFESDFIQISKRGEVIDVHNR 65

Query: 66  VRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLR 125
            RMVTMGI RTSP L LPDVMLLARPA  C+  A  G AT++++   A+ LELTRLLPL 
Sbjct: 66  ARMVTMGIVRTSPCLTLPDVMLLARPAAVCDN-ARCGPATQKRESPPAEILELTRLLPLM 124

Query: 126 FVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPMESNSSTC 185
           FV+I++ +  K+QL LK ATGRS YLQLCP  D  +DLF +WE L+Y+LRPP+E+ S T 
Sbjct: 125 FVKITIHNSVKKQLHLKLATGRSFYLQLCPPSDASEDLFVHWENLVYILRPPVEAYSDTR 184

Query: 186 GIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAY 238
            I A + +   V +E +RS     ++   +++Q  I  LHM +E+ G+T   Y
Sbjct: 185 AILAGNTLDSSVLEEVQRSPVGYAMKFCEEKEQFRISRLHMNAEMFGSTYCDY 237


>gi|89363024 hypothetical protein LOC161142 [Homo sapiens]
          Length = 422

 Score =  107 bits (266), Expect = 4e-23
 Identities = 63/147 (42%), Positives = 84/147 (57%), Gaps = 1/147 (0%)

Query: 28  LQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNRVRMVTMGIARTSPILPLPDVML 87
           LQ  L  GEY  F   P+ ES+FIQ+ +RGE I +HNR   VT+GI  +S    +P+VML
Sbjct: 29  LQNMLDGGEYAPFVSPPMLESNFIQVNRRGESIYLHNRANWVTVGICFSSSTHKIPNVML 88

Query: 88  LARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEKQQLRLKFATGR 147
           LA    G ++               A+ L LTR LPL+FV +SV D E   L++K  +GR
Sbjct: 89  LAHLTPGAQKDT-ETLFKSLLTSPPAEKLVLTRFLPLQFVTLSVHDAENMSLKVKLVSGR 147

Query: 148 SCYLQLCPALDTRDDLFAYWEKLIYLL 174
           + YLQLC +   +D LF+ W  LI LL
Sbjct: 148 AYYLQLCTSAYKQDTLFSQWVALISLL 174


>gi|76253859 hypothetical protein LOC112703 [Homo sapiens]
          Length = 231

 Score =  106 bits (265), Expect = 5e-23
 Identities = 64/149 (42%), Positives = 86/149 (57%), Gaps = 24/149 (16%)

Query: 27  KLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNRVRMVTMGIARTSPILPLPDVM 86
           +LQR L  GE+D F+  PIFES+F+Q+T+ GEV +       VTMG+A +SP L LPD++
Sbjct: 95  RLQRYLQSGEFDQFRDFPIFESNFVQVTRLGEVANE------VTMGVAASSPALELPDLL 148

Query: 87  LLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEKQQLRLKFATG 146
           LLA PA                  K   +L+L  L PL+FV++ V D  + QL +K  T 
Sbjct: 149 LLAGPA------------------KENGHLQLFGLFPLKFVQLFVHDKSRCQLEVKLNTS 190

Query: 147 RSCYLQLCPALDTRDDLFAYWEKLIYLLR 175
           R+ YLQL   L TRD  F  W +L+Y LR
Sbjct: 191 RTFYLQLRAPLKTRDREFGQWVRLLYRLR 219


>gi|223972704 hypothetical protein LOC284418 [Homo sapiens]
          Length = 922

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 56/157 (35%), Positives = 87/157 (55%), Gaps = 24/157 (15%)

Query: 25  MGKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNRVRMVTMGIARTSPILPLPD 84
           +G+LQ+ L KGEY   +  P+FES+F+Q+T +G  + V++R   + MG+A + P L LPD
Sbjct: 23  LGELQKTLQKGEYLPLRPLPMFESNFVQVTHQGGPVFVNHRTNRLAMGVAASLPGLVLPD 82

Query: 85  VMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEKQQLRLKFA 144
           ++L+ +PA                + +    L LTR++PL  V + V D    +L+L+  
Sbjct: 83  ILLIGQPA----------------EDRDCSGLVLTRMIPLDLVHLCVHDLSAWRLKLRLV 126

Query: 145 TGRSCYLQLCPALDTRDD----LFAYWEKLIYLLRPP 177
           +GR  YL    ALD  D+    LF  W +LI LL+ P
Sbjct: 127 SGRQYYL----ALDAPDNEVGFLFHCWVRLINLLQEP 159


>gi|14211935 testes development-related NYD-SP18 [Homo sapiens]
          Length = 344

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 58/209 (27%), Positives = 104/209 (49%), Gaps = 22/209 (10%)

Query: 26  GKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNRVRMVTMGIARTSPILPLPDV 85
           G L R ++  E+++F  + +FES+FIQ+ +     DV+     + +G+  + P LPLP++
Sbjct: 57  GLLCRVVHSPEFNLFLDSVVFESNFIQVKRGRNWRDVYKASNTMALGVTSSVPCLPLPNI 116

Query: 86  MLLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEKQQLRLKFAT 145
           +L+A      + + G  Q   R     A N+ L R+LPLRFV + V DH ++ L+L+  T
Sbjct: 117 LLMA----SVKWHQGQNQTWNRP--SIAPNIFLKRILPLRFVELQVCDHYQRILQLRTVT 170

Query: 146 GRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPMESNS-------------STCGIPAED- 191
            +  YL+L P  D  + +F +W +L+ +L+  +   +               C  P+ D 
Sbjct: 171 EKIYYLKLHP--DHPETVFHFWIRLVQILQKGLSITTKDPRILVTHCLVPKNCSSPSGDS 228

Query: 192 MMWMPVFQEDRRSLGAVNLQGKGDQDQVS 220
            +     Q  + S   + L  KG+ + +S
Sbjct: 229 KLVQKKLQASQPSESLIQLMTKGESEALS 257


>gi|193083150 hypothetical protein LOC346653 isoform b [Homo
           sapiens]
          Length = 300

 Score = 72.8 bits (177), Expect = 8e-13
 Identities = 46/150 (30%), Positives = 81/150 (54%), Gaps = 8/150 (5%)

Query: 26  GKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNRVRMVTMGIARTSPILPLPDV 85
           G L + ++  E+++F  + +FES+FIQ+TK G   DV      V +G+  + P LPLP+V
Sbjct: 25  GLLCQLIHSPEFNLFSNSVVFESNFIQVTKPGNWRDVCEGSATVILGVTSSVPSLPLPNV 84

Query: 86  MLLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEKQQLRLKFAT 145
           +L+A            G  T       A  + L+RLLPL++V + + D  ++ LR++  T
Sbjct: 85  LLMANVTW------PQGPFTTWSTPGDAPVINLSRLLPLKYVELRIYDRLQRILRVRTVT 138

Query: 146 GRSCYLQLCPALDTRDDLFAYWEKLIYLLR 175
            +  YL+L       + +F +W +L+ +L+
Sbjct: 139 EKIYYLKLHE--KHPEIVFQFWVRLVKILQ 166


>gi|149192824 hypothetical protein LOC346653 isoform a [Homo
           sapiens]
          Length = 309

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 46/159 (28%), Positives = 81/159 (50%), Gaps = 17/159 (10%)

Query: 26  GKLQRQLYKGEYDIFKYAPIFESDFIQ---------ITKRGEVIDVHNRVRMVTMGIART 76
           G L + ++  E+++F  + +FES+FIQ         +TK G   DV      V +G+  +
Sbjct: 25  GLLCQLIHSPEFNLFSNSVVFESNFIQTHVPEADFQVTKPGNWRDVCEGSATVILGVTSS 84

Query: 77  SPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEK 136
            P LPLP+V+L+A            G  T       A  + L+RLLPL++V + + D  +
Sbjct: 85  VPSLPLPNVLLMANVTW------PQGPFTTWSTPGDAPVINLSRLLPLKYVELRIYDRLQ 138

Query: 137 QQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLR 175
           + LR++  T +  YL+L       + +F +W +L+ +L+
Sbjct: 139 RILRVRTVTEKIYYLKLHE--KHPEIVFQFWVRLVKILQ 175


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 68/322 (21%), Positives = 123/322 (38%), Gaps = 21/322 (6%)

Query: 263 STELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGG 322
           S+  + E +T    E++   + A  AT + +  +S  A+ +   + S   +GA+T     
Sbjct: 155 SSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSE 214

Query: 323 NKGNMALAGTASMAPNSTKVAVAGAA--GKSSEHVSSASMSLSREGSVSLAIAGVVLTSR 380
           ++     AGTA+ + +ST  + A  A   +SS   S A  + + E S + + AG    + 
Sbjct: 215 SRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAG----TA 270

Query: 381 TAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRR 440
           T +E+   ++    V+  +S +  SG +    +++S                    +   
Sbjct: 271 TNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTA 330

Query: 441 RTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISK 500
              ES   + G   A  S S ++ S           G     +S    +  G S    S+
Sbjct: 331 TNSESSTTSSGASTATNSESSTTSS-----------GASTATNSGSSTTSSGTSTATNSE 379

Query: 501 ESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTKVVGTPHGRDVDVMAKMAERS 560
            S  S  SG S  TTS  S+   G  +S   N  ++  +    T    +    +  A  +
Sbjct: 380 SSTVS--SGASTATTSESSTTSSG--ASTATNSESSTVSSGASTATNSESSTTSSGANTA 435

Query: 561 TNVAIAETAEGGQGLEMVGSMT 582
           TN   + T+ G     + G  T
Sbjct: 436 TNSGSSVTSAGSGTAALTGMHT 457



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 63/307 (20%), Positives = 115/307 (37%), Gaps = 25/307 (8%)

Query: 278 AAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAP 337
           ++    A  +   TV+  +S+A  + +    S   +GA+T     +    + A TA+ + 
Sbjct: 84  SSGISTATNSEFSTVSSGISIATNSES----STTSSGASTATNSESSTPSSGASTATNSD 139

Query: 338 NSTKVAVAGAAGKSSEHVSS--ASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPV 395
           +ST  + A  A  S    +S  AS + + E S + + A     S ++  +   + A    
Sbjct: 140 SSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSE 199

Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
           S+  S  + +  +   RT ++  G     E          +++     ES   + G   A
Sbjct: 200 SSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATN----SESSTPSSGAGTA 255

Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTT 515
             S S ++ S           G G   +S       G+S    S+ S  S  SG +  T 
Sbjct: 256 TNSESSTTSS-----------GAGTATNSESSTVSSGISTVTNSESSTPS--SGANTATN 302

Query: 516 SSGSSKGLGRVSSFLRNVRANLTTKVVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGL 575
           S  S+   G  ++   N  ++ T+    T    +    +  A  +TN   + T+ G    
Sbjct: 303 SESSTTSSG--ANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTA 360

Query: 576 EMVGSMT 582
              GS T
Sbjct: 361 TNSGSST 367



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 37/171 (21%), Positives = 70/171 (40%), Gaps = 19/171 (11%)

Query: 232 GATSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGT 291
           GA++A  +G     +  +  TN         S+ ++   +T    E++   + A  AT +
Sbjct: 356 GASTATNSGSSTTSSGTSTATN-------SESSTVSSGASTATTSESSTTSSGASTATNS 408

Query: 292 VAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKS 351
            +  +S  A+ +   + S   +GA T    G+    A +GTA++    T           
Sbjct: 409 ESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHT----------- 457

Query: 352 SEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKS 402
           + H +S ++S ++ G  SL    + L +  +  A +   AG     R S S
Sbjct: 458 TSHSASTAVSEAKPGG-SLVPWEIFLITLVSVVAAVGLFAGLFFCVRNSLS 507


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 41/136 (30%), Positives = 62/136 (45%), Gaps = 16/136 (11%)

Query: 399  QSKSSLSGQH-GRERTQASAEGCKE----GRERREKDRALGRSSHRRRTGESRHKTRGDK 453
            +SK S S +H  R+RT  S    ++     +  R + R+  RS  RRR+  SR K+RG +
Sbjct: 1825 RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRR 1884

Query: 454  IAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLW 513
               K   + S  HR+   ++K K       S  RD+ K      +   SRT  +  RS  
Sbjct: 1885 SVSKEKRKRSPKHRSKSRERKRK------RSSSRDNRK-----TVRARSRTPSRRSRSHT 1933

Query: 514  TTSSGSSKGLGRVSSF 529
             +    S+ +GR  SF
Sbjct: 1934 PSRRRRSRSVGRRRSF 1949



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 22/165 (13%)

Query: 362  LSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRE------RTQA 415
            + R  S+   I G +L S    +    +AA P VS+   ++S S    ++      + + 
Sbjct: 1742 MERLTSLRAGIEGPLLASDVGRDR---SAASPVVSSMPERASESSSEEKDDYEIFVKVKD 1798

Query: 416  SAEGCKEGRER----REKDRALGRSSHRRRTGESRHKTR-----GDKIAQKSSSRSSFSH 466
            + E  K+ + R    +EK R     S  +R+  S HK+R         A+K SS+S  SH
Sbjct: 1799 THEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSK-SH 1857

Query: 467  RANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511
            R ++   + +      SSR R   +G     +SKE R      RS
Sbjct: 1858 R-SQTRSRSRSRRRRRSSRSRSKSRG--RRSVSKEKRKRSPKHRS 1899



 Score = 33.5 bits (75), Expect = 0.57
 Identities = 33/124 (26%), Positives = 56/124 (45%), Gaps = 10/124 (8%)

Query: 396  STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSS----HRRRTGESRHKTRG 451
            S  + +SS S  H R +T++ +   +  R  R + ++ GR S     R+R+ + R K+R 
Sbjct: 1845 SRARKRSSKSKSH-RSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRE 1903

Query: 452  DKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKG----VSHTPISKESRTSHK 507
             K  + SS  +  + RA       +   +  S R R    G     S +P S+ SRT  +
Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISP-SRRSRTPSR 1962

Query: 508  SGRS 511
              R+
Sbjct: 1963 RSRT 1966


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 41/136 (30%), Positives = 62/136 (45%), Gaps = 16/136 (11%)

Query: 399  QSKSSLSGQH-GRERTQASAEGCKE----GRERREKDRALGRSSHRRRTGESRHKTRGDK 453
            +SK S S +H  R+RT  S    ++     +  R + R+  RS  RRR+  SR K+RG +
Sbjct: 1825 RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRR 1884

Query: 454  IAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLW 513
               K   + S  HR+   ++K K       S  RD+ K      +   SRT  +  RS  
Sbjct: 1885 SVSKEKRKRSPKHRSKSRERKRK------RSSSRDNRK-----TVRARSRTPSRRSRSHT 1933

Query: 514  TTSSGSSKGLGRVSSF 529
             +    S+ +GR  SF
Sbjct: 1934 PSRRRRSRSVGRRRSF 1949



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 22/165 (13%)

Query: 362  LSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRE------RTQA 415
            + R  S+   I G +L S    +    +AA P VS+   ++S S    ++      + + 
Sbjct: 1742 MERLTSLRAGIEGPLLASDVGRDR---SAASPVVSSMPERASESSSEEKDDYEIFVKVKD 1798

Query: 416  SAEGCKEGRER----REKDRALGRSSHRRRTGESRHKTR-----GDKIAQKSSSRSSFSH 466
            + E  K+ + R    +EK R     S  +R+  S HK+R         A+K SS+S  SH
Sbjct: 1799 THEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSK-SH 1857

Query: 467  RANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511
            R ++   + +      SSR R   +G     +SKE R      RS
Sbjct: 1858 R-SQTRSRSRSRRRRRSSRSRSKSRG--RRSVSKEKRKRSPKHRS 1899



 Score = 33.5 bits (75), Expect = 0.57
 Identities = 33/124 (26%), Positives = 56/124 (45%), Gaps = 10/124 (8%)

Query: 396  STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSS----HRRRTGESRHKTRG 451
            S  + +SS S  H R +T++ +   +  R  R + ++ GR S     R+R+ + R K+R 
Sbjct: 1845 SRARKRSSKSKSH-RSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRE 1903

Query: 452  DKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKG----VSHTPISKESRTSHK 507
             K  + SS  +  + RA       +   +  S R R    G     S +P S+ SRT  +
Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISP-SRRSRTPSR 1962

Query: 508  SGRS 511
              R+
Sbjct: 1963 RSRT 1966


>gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]
          Length = 352

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 63/240 (26%), Positives = 97/240 (40%), Gaps = 28/240 (11%)

Query: 275 IKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTAS 334
           ++ A  AG   GA  G +      A    A  + +A   GAA+ D G             
Sbjct: 1   MERAGPAGEEGGAREGRLLPRAPGAWVLRACAERAALEVGAASADTG------------- 47

Query: 335 MAPNSTKVAVAGAAGKSSEHVSSASMSLSREGS--VSLAIAGVVLTSRTAAEA-DMDAAA 391
                  V   GA G +   ++SA    +R+G+  V    +G  L SR A+ A     A+
Sbjct: 48  -------VRGCGARGPAPL-LASAGGGRARDGTWGVRTKGSGAALPSRPASRAAPRPEAS 99

Query: 392 GPPVSTRQSKSSLSG-QHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTR 450
            PP+   +++  LSG Q GR R   +  G +  +  R + R+ GR S +R+  +SR  T 
Sbjct: 100 SPPLPLEKARGGLSGPQGGRARGAMAHVGSR--KRSRSRSRSRGRGSEKRKK-KSRKDTS 156

Query: 451 GDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR 510
            +  A  S  R + +     +  K+K      SS    S    S +  S  S +S   GR
Sbjct: 157 RNCSASTSQGRKASTAPGAEERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGR 216


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 80/347 (23%), Positives = 123/347 (35%), Gaps = 41/347 (11%)

Query: 251 PTNVLNASIPKTSTELAEEPATGGIKEAAAA--------------GAAAGAATGTVAGAL 296
           P   L A++ +T  ELA E A   +  AAA                AAAG     + G  
Sbjct: 18  PGAPLGAALARTPVELAAESAAPALSAAAAGVKILGSGDKKLRRQKAAAGGKKARLRGQK 77

Query: 297 SVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAG--AAGKSSE- 353
              A   A      A       + GG +   A AGT S+     K    G  AA   S+ 
Sbjct: 78  GAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRGRKPRRRGQKAAATGSKK 137

Query: 354 -----HVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQH 408
                  S+A+ S +R      A A   + S+   +    AAAG          S SG+ 
Sbjct: 138 PRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAG--------AKSRSGKK 189

Query: 409 GRER-TQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHR 467
            R R  ++  +  K+GR+R  K R  G++    R G  +   R    A  + SR     +
Sbjct: 190 PRRRGAKSRGDEDKKGRQREAKSR-FGKT----RGGRRKKHRRPKPAAGGAKSRRGGGKK 244

Query: 468 ANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVS 527
             +  ++ +     G SR   S  G       K+ R   ++         G++    + +
Sbjct: 245 PQKQRRRGQKAATGGKSRVGKSRGGG-----DKKLRRQGQNAALAGAKRRGAATAGEKPA 299

Query: 528 SFLRNVRANLTTKVVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQG 574
           +  R  R   +        GR      +  +++T  A A T  GG G
Sbjct: 300 AKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGG 346



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 61/265 (23%), Positives = 92/265 (34%), Gaps = 22/265 (8%)

Query: 276 KEAAAAGAAAGAATG------TVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMAL 329
           ++A AAGA +            VAGA S    + +  +  A  AGA +   GGNK +   
Sbjct: 511 EKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRGG 570

Query: 330 AGTASMAPNSTKVAVAGAAGKSSE---HVSSASMSLSREGS-------VSLAIAGVVLTS 379
            G        T  A     G   +     ++A ++ SR G           A  G     
Sbjct: 571 GGNKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKSRK 630

Query: 380 RTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHR 439
           +       DAAA        + S  SG       + +A G +          A  R   R
Sbjct: 631 KPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPR 690

Query: 440 RRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPIS 499
           RR    R K+RGD   Q ++   +   R  +  +  K  G  G ++ R S    S     
Sbjct: 691 RR----RAKSRGDG-GQNAAVGINPWQRRGKKPRLGKSRGG-GGAKSRGSGGAKSRGSGG 744

Query: 500 KESRTSHKSGRSLWTTSSGSSKGLG 524
            +SR+  K+  S      G+ +  G
Sbjct: 745 AKSRSGKKAAASKSHGGGGAKRRRG 769



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 61/280 (21%), Positives = 96/280 (34%), Gaps = 48/280 (17%)

Query: 320 AGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTS 379
           AGG K                + A  G   +  +        L R+G  + A+AG     
Sbjct: 232 AGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQ-NAALAGA--KR 288

Query: 380 RTAAEA-DMDAAAGPPVSTRQSKSSLSGQH-------------GRERTQASAEGCKEGR- 424
           R AA A +  AA G      +   SL GQ+             G++ T+A+A G K G  
Sbjct: 289 RGAATAGEKPAAKG---RGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGG 345

Query: 425 ----------ERREKDRALGRSSHRRRTGESRHKTR--GDKIAQKSSSRSSFSHRANRDD 472
                     + R+K R  G+   R++   +  K+R  GDK   + + R         D 
Sbjct: 346 GQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRG-------DG 398

Query: 473 KKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRN 532
           +K+    NP     R + K  +  P    S+   + G     +  G S+  G      R 
Sbjct: 399 RKKPRWQNP----RRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRG 454

Query: 533 VRANLTTKVVGTPHGRDVDVMAKMAERSTNVAIAETAEGG 572
            +A       G     D     K   +  + A  ++  GG
Sbjct: 455 QKARQKAAEAGAESRGD----KKQGRQKASAAGTKSRGGG 490


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 42/153 (27%), Positives = 67/153 (43%), Gaps = 9/153 (5%)

Query: 379 SRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSH 438
           S+   +A  +  +    S R+S+S     H R  +++S+      R R     +    S 
Sbjct: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSR 240

Query: 439 RRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPI 498
            R +   R ++RG K   +SSSR   SHR +   +K +   +  SS  R+  +  S +  
Sbjct: 241 SRSSSRERSRSRGSK--SRSSSR---SHRGSSSPRK-RSYSSSSSSPERNRKRSRSRSSS 294

Query: 499 S---KESRTSHKSGRSLWTTSSGSSKGLGRVSS 528
           S   K+ RT  +S      +SSGSS    R SS
Sbjct: 295 SGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 7/115 (6%)

Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRER-REKDRALG---RSSHRRRTGESRHKTRG 451
           S+R S  S S    R R+++S+      R   RE+ R+ G   RSS R   G S  + R 
Sbjct: 214 SSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRS 273

Query: 452 DKIAQKSSSRS---SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESR 503
              +  S  R+   S S  ++  D+K++   +    R   S  G SH+     S+
Sbjct: 274 YSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 32/127 (25%), Positives = 52/127 (40%), Gaps = 8/127 (6%)

Query: 350 KSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHG 409
           +SS   SS S S SR  S S + +     SR+++     +      S   S+S       
Sbjct: 212 RSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSK--SRSSSRSHRGSSSP 269

Query: 410 RERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRAN 469
           R+R+ +S+    E   +R + R+      ++R   SR   R      +  S S  SH  +
Sbjct: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPER------RHRSSSGSSHSGS 323

Query: 470 RDDKKEK 476
           R   K+K
Sbjct: 324 RSSSKKK 330


>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
          Length = 1512

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 70/246 (28%), Positives = 94/246 (38%), Gaps = 38/246 (15%)

Query: 287 AATGTVAGALSVAAANSA------PGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNST 340
           AA GT A A + AAA+S+      P +V     G     AGG +           A    
Sbjct: 62  AAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRR--AGGRQKRRRGPRAGQEAEKRR 119

Query: 341 KVAVA-----GAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPV 395
             ++      G  G SS      +  +  E   S +  G++L   +AA A    AAG   
Sbjct: 120 VFSLPQPQQDGGGGASSG--GGVTPLVEYEDVSSQSEQGLLLGGASAATAA--TAAGGTG 175

Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
            +  S +S SG      TQ   EG  E R RR++  + GRS  R R    R   RG   A
Sbjct: 176 GSGGSPASSSG------TQRRGEG-SERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEA 228

Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPG--------------SSRHRDSHKGVSHTPISKE 501
            KS SR S S     +  K     + G              S + RDS    S T  SKE
Sbjct: 229 SKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKE 288

Query: 502 SRTSHK 507
             +++K
Sbjct: 289 PPSAYK 294



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 64/240 (26%), Positives = 92/240 (38%), Gaps = 20/240 (8%)

Query: 296 LSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHV 355
           L +AA  +A    +AA A ++    G       LA     A    K      AG+ +E  
Sbjct: 59  LFLAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKR 118

Query: 356 SSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQA 415
              S+   ++     A +G  +T     E          VS++  +  L G      T A
Sbjct: 119 RVFSLPQPQQDGGGGASSGGGVTPLVEYE---------DVSSQSEQGLLLGG-ASAATAA 168

Query: 416 SAEGCKEGRERREKDRALGRSSHRRRTGE-SRHKTRGDKIAQKSSSRSSFSHRANRDDKK 474
           +A G   G        +   SS  +R GE S  + R D+  + SS RS   HR +R    
Sbjct: 169 TAAGGTGG-----SGGSPASSSGTQRRGEGSERRPRRDR--RSSSGRSKERHREHRRRDG 221

Query: 475 EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR--SLWTTSSGSSKGLGRVSSFLRN 532
           ++G      SR R SH G     ++K   +S   GR  S   TSS SS    R S   R+
Sbjct: 222 QRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRS 281


>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
          Length = 1452

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 70/246 (28%), Positives = 94/246 (38%), Gaps = 38/246 (15%)

Query: 287 AATGTVAGALSVAAANSA------PGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNST 340
           AA GT A A + AAA+S+      P +V     G     AGG +           A    
Sbjct: 62  AAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRR--AGGRQKRRRGPRAGQEAEKRR 119

Query: 341 KVAVA-----GAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPV 395
             ++      G  G SS      +  +  E   S +  G++L   +AA A    AAG   
Sbjct: 120 VFSLPQPQQDGGGGASSG--GGVTPLVEYEDVSSQSEQGLLLGGASAATAA--TAAGGTG 175

Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
            +  S +S SG      TQ   EG  E R RR++  + GRS  R R    R   RG   A
Sbjct: 176 GSGGSPASSSG------TQRRGEG-SERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEA 228

Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPG--------------SSRHRDSHKGVSHTPISKE 501
            KS SR S S     +  K     + G              S + RDS    S T  SKE
Sbjct: 229 SKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKE 288

Query: 502 SRTSHK 507
             +++K
Sbjct: 289 PPSAYK 294



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 64/240 (26%), Positives = 92/240 (38%), Gaps = 20/240 (8%)

Query: 296 LSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHV 355
           L +AA  +A    +AA A ++    G       LA     A    K      AG+ +E  
Sbjct: 59  LFLAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKR 118

Query: 356 SSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQA 415
              S+   ++     A +G  +T     E          VS++  +  L G      T A
Sbjct: 119 RVFSLPQPQQDGGGGASSGGGVTPLVEYE---------DVSSQSEQGLLLGG-ASAATAA 168

Query: 416 SAEGCKEGRERREKDRALGRSSHRRRTGE-SRHKTRGDKIAQKSSSRSSFSHRANRDDKK 474
           +A G   G        +   SS  +R GE S  + R D+  + SS RS   HR +R    
Sbjct: 169 TAAGGTGG-----SGGSPASSSGTQRRGEGSERRPRRDR--RSSSGRSKERHREHRRRDG 221

Query: 475 EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR--SLWTTSSGSSKGLGRVSSFLRN 532
           ++G      SR R SH G     ++K   +S   GR  S   TSS SS    R S   R+
Sbjct: 222 QRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRS 281


>gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens]
          Length = 338

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 62/240 (25%), Positives = 98/240 (40%), Gaps = 39/240 (16%)

Query: 275 IKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTAS 334
           ++ A  AG   GA  G +      A    A  + +A   GAA+ D G             
Sbjct: 1   MERAGPAGEEGGAREGRLLPRAPGAWVLRACAERAALEVGAASADTG------------- 47

Query: 335 MAPNSTKVAVAGAAGKSSEHVSSASMSLSREGS--VSLAIAGVVLTSRTAAEA-DMDAAA 391
                  V   GA G +   ++SA    +R+G+  V    +G  L SR A+ A     A+
Sbjct: 48  -------VRGCGARGPAPL-LASAGGGRARDGTWGVRTKGSGAALPSRPASRAAPRPEAS 99

Query: 392 GPPVSTRQSKSSLSG-QHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTR 450
            PP+   +++  LSG Q GR R   +  G +  +  R + R+ GR S +R+         
Sbjct: 100 SPPLPLEKARGGLSGPQGGRARGAMAHVGSR--KRSRSRSRSRGRGSEKRK--------- 148

Query: 451 GDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR 510
             K ++K +SR+  S   +++  K+K      SS    S    S +  S  S +S   GR
Sbjct: 149 --KKSRKDTSRNC-SASTSQERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGR 205



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 30/154 (19%), Positives = 64/154 (41%), Gaps = 2/154 (1%)

Query: 282 GAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTK 341
           G+ A   +   + A     A+S P  +  A  G +    G  +G MA  G+   + + ++
Sbjct: 79  GSGAALPSRPASRAAPRPEASSPPLPLEKARGGLSGPQGGRARGAMAHVGSRKRSRSRSR 138

Query: 342 VAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSK 401
               G+  +  +     S + S   S S   +      RT + +   +++    S+  S 
Sbjct: 139 SRGRGSEKRKKKSRKDTSRNCS--ASTSQERSKQKARRRTRSSSSSSSSSSSSSSSSSSS 196

Query: 402 SSLSGQHGRERTQASAEGCKEGRERREKDRALGR 435
           SS S   GR++     +  ++ +++R+K +  G+
Sbjct: 197 SSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGK 230


>gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens]
          Length = 341

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 62/240 (25%), Positives = 98/240 (40%), Gaps = 39/240 (16%)

Query: 275 IKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTAS 334
           ++ A  AG   GA  G +      A    A  + +A   GAA+ D G             
Sbjct: 1   MERAGPAGEEGGAREGRLLPRAPGAWVLRACAERAALEVGAASADTG------------- 47

Query: 335 MAPNSTKVAVAGAAGKSSEHVSSASMSLSREGS--VSLAIAGVVLTSRTAAEA-DMDAAA 391
                  V   GA G +   ++SA    +R+G+  V    +G  L SR A+ A     A+
Sbjct: 48  -------VRGCGARGPAPL-LASAGGGRARDGTWGVRTKGSGAALPSRPASRAAPRPEAS 99

Query: 392 GPPVSTRQSKSSLSG-QHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTR 450
            PP+   +++  LSG Q GR R   +  G +  +  R + R+ GR S +R+         
Sbjct: 100 SPPLPLEKARGGLSGPQGGRARGAMAHVGSR--KRSRSRSRSRGRGSEKRK--------- 148

Query: 451 GDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR 510
             K ++K +SR+  S   +++  K+K      SS    S    S +  S  S +S   GR
Sbjct: 149 --KKSRKDTSRNC-SASTSQERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGR 205



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 30/154 (19%), Positives = 64/154 (41%), Gaps = 2/154 (1%)

Query: 282 GAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTK 341
           G+ A   +   + A     A+S P  +  A  G +    G  +G MA  G+   + + ++
Sbjct: 79  GSGAALPSRPASRAAPRPEASSPPLPLEKARGGLSGPQGGRARGAMAHVGSRKRSRSRSR 138

Query: 342 VAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSK 401
               G+  +  +     S + S   S S   +      RT + +   +++    S+  S 
Sbjct: 139 SRGRGSEKRKKKSRKDTSRNCS--ASTSQERSKQKARRRTRSSSSSSSSSSSSSSSSSSS 196

Query: 402 SSLSGQHGRERTQASAEGCKEGRERREKDRALGR 435
           SS S   GR++     +  ++ +++R+K +  G+
Sbjct: 197 SSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGK 230


>gi|24497554 homeobox A13 [Homo sapiens]
          Length = 388

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 41/116 (35%), Positives = 48/116 (41%), Gaps = 16/116 (13%)

Query: 278 AAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAP 337
           AAAA AAA AA G   G     AA +A G  S A A AA   A  N+    +A  A +AP
Sbjct: 40  AAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAP 99

Query: 338 NSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGP 393
                   GAA        SA  S   E   S A A     +  AA A   ++ GP
Sbjct: 100 --------GAA--------SAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGP 139



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 38/154 (24%), Positives = 56/154 (36%), Gaps = 6/154 (3%)

Query: 240 GGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVA 299
           GG  + ++ NK      A+    +   A     GG    AAA A    +    A A + A
Sbjct: 23  GGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAA 82

Query: 300 AANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSAS 359
           AAN    Q    +A  A +  G      +  G A   P++   A A AA  ++   +S+S
Sbjct: 83  AAN----QCRNLMAHPAPLAPGAASAYSSAPGEA--PPSAAAAAAAAAAAAAAAAAASSS 136

Query: 360 MSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGP 393
                 G      A        AA++    AA P
Sbjct: 137 GGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALP 170



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 25/95 (26%), Positives = 35/95 (36%)

Query: 228 SEVCGATSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGA 287
           S    A +AA A     +N    P  +   +    S+   E P +     AAAA AAA A
Sbjct: 71  SVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAA 130

Query: 288 ATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGG 322
           A  + +G    A    A      +   AA   + G
Sbjct: 131 AAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSG 165


>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
           sapiens]
          Length = 674

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 57/239 (23%), Positives = 89/239 (37%), Gaps = 9/239 (3%)

Query: 273 GGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGT 332
           GG  E AAA AAA AA+G   G          P     A A   +  +  +      + +
Sbjct: 333 GGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSS 392

Query: 333 ASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAG 392
            S + +S++    G   +S  H  S S S SR  S S         SR+ +     +  G
Sbjct: 393 RSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRY------SRSRSRGRRHSGGG 446

Query: 393 PPVSTRQSKS-SLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRG 451
                R S+S +  G +G  R   S     + R RR        SS R R+  S   +R 
Sbjct: 447 SRDGHRYSRSPARRGGYGPRRRSRSRSHSGD-RYRRGGRGLRHHSSSRSRSSWSLSPSRS 505

Query: 452 DKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR 510
             + +  S   S S   +R   + +   +P  +R + +    S     K  +T   +G+
Sbjct: 506 RSLTRSRSHSPSPSQSRSRSRSRSQS-PSPSPAREKLTRPAASPAVGEKLKKTEPAAGK 563


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 67/331 (20%), Positives = 127/331 (38%), Gaps = 17/331 (5%)

Query: 212 GKGDQDQVSIQSLHMVSEVCGATSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPA 271
           G G Q   S QS   V    G+  ++  G  G  + ++       +   +TS     E  
Sbjct: 295 GHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESG 354

Query: 272 TGGIKEAAAAGAAAGAAT-----GTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGN 326
           +G     +  G+ +G ++     G+ +G  S +  + +  + S++     +     +   
Sbjct: 355 SGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRG 414

Query: 327 MALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSR----EGSVSLAIAGVVLTSRTA 382
              +G+     +  + + +G +  S +H +    S S      GS   +  G   +S   
Sbjct: 415 QHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEH 474

Query: 383 AEADMDAAAGPPVSTRQSK-SSLSGQHGRERTQASAEGCKE--GRERREKDRALGRSSHR 439
           +       +G   S+   +  S SGQ  R   Q S+ G     G+      ++LG S H 
Sbjct: 475 SSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHG 534

Query: 440 RRTGESRHKTRG--DKIAQKSSSRSSFSHRANRDDKK---EKGCGNPGSSRHRDSHKGVS 494
             +G+S   +RG  +  +++SSS     + + R   +   E G G+     H++S  G S
Sbjct: 535 SGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQS 594

Query: 495 HTPISKESRTSHKSGRSLWTTSSGSSKGLGR 525
                  S + H S      ++SG S   G+
Sbjct: 595 SGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQ 625



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 1/127 (0%)

Query: 402 SSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSR 461
           SS  GQHG    QAS+ G      R+        S+ R  +G  +H + G   +     R
Sbjct: 371 SSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSS-GSGQSPGHGQR 429

Query: 462 SSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSK 521
            S S ++    +   G G   SS    S  G S      ES + H SG +   + SG S 
Sbjct: 430 GSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSS 489

Query: 522 GLGRVSS 528
           G G+  S
Sbjct: 490 GHGQHGS 496



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 56/234 (23%), Positives = 89/234 (38%), Gaps = 24/234 (10%)

Query: 299 AAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKV--AVAGAAGKSSEHVS 356
           +++N   G VS   +G       G     +  G+ S   +  +   + +G + +S +H S
Sbjct: 685 SSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGS 744

Query: 357 SASMSLS--REGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQ 414
           S+ +S S  + GS S   +G       +  +      G    +    SS  GQHG   + 
Sbjct: 745 SSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHG----SSSGHSSSHGQHGSGTSC 800

Query: 415 ASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKK 474
           +S+ G  E        +A G   H   +G+          +Q  S+   FS +       
Sbjct: 801 SSSCGHYESGS----GQASGFGQHESGSGQG--------YSQHGSASGHFSSQGRHGSTS 848

Query: 475 EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSS 528
               G   SS   DS  G S +    ES + H SGR    + SG S G G+  S
Sbjct: 849 ----GQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGS 898



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 55/215 (25%), Positives = 81/215 (37%), Gaps = 18/215 (8%)

Query: 321  GGNKGNMALAGT-ASMAPNSTKVAVAGAA-GKSSEHV-----SSASMSLSREGSVSLAIA 373
            G + G+ +  G   S +  S+     GA+ G+SS H      SS S    R+GS S    
Sbjct: 1067 GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 1126

Query: 374  GVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRAL 433
            G       + ++      G    +   +SS SGQHG    ++S  G  E    +    + 
Sbjct: 1127 GHGQRGSGSRQSPSYGRHG----SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 1182

Query: 434  GRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGV 493
              S     +G  +H   G +  Q S      S   +     + G G+  SS H     G 
Sbjct: 1183 HGSGSGHSSGYGQH---GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS 1239

Query: 494  SHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSS 528
             H+P    SR  H SG    ++      G GR SS
Sbjct: 1240 GHSP----SRGRHGSGLGHSSSHGQHGSGSGRSSS 1270



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 55/215 (25%), Positives = 81/215 (37%), Gaps = 18/215 (8%)

Query: 321  GGNKGNMALAGT-ASMAPNSTKVAVAGAA-GKSSEHV-----SSASMSLSREGSVSLAIA 373
            G + G+ +  G   S +  S+     GA+ G+SS H      SS S    R+GS S    
Sbjct: 2007 GSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 2066

Query: 374  GVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRAL 433
            G       + ++      G    +   +SS SGQHG    ++S  G  E    +    + 
Sbjct: 2067 GHGQRGSGSRQSPSYGRHG----SGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQ 2122

Query: 434  GRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGV 493
              S     +G  +H   G +  Q S      S   +     + G G+  SS H     G 
Sbjct: 2123 HGSGSGHSSGYGQH---GSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGS 2179

Query: 494  SHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSS 528
             H+P    SR  H SG    ++      G GR SS
Sbjct: 2180 GHSP----SRGRHGSGSGHSSSHGQHGSGSGRSSS 2210



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 9/134 (6%)

Query: 397  TRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQ 456
            +R  +SS S QHG     +S+ G + G   R+   +LG   H   +G+S   +RG   + 
Sbjct: 962  SRSGQSSRSEQHGSSSGSSSSYG-QHGSGSRQ---SLGHGQHGSGSGQSPSPSRGRHGSG 1017

Query: 457  KSSSRSSFSHRANRDDKK-----EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511
               S S   +R+           E G G+     HR+S  G S       S + H S   
Sbjct: 1018 SGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 1077

Query: 512  LWTTSSGSSKGLGR 525
               ++SG S   G+
Sbjct: 1078 QHGSTSGQSSSCGQ 1091



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 7/137 (5%)

Query: 396  STRQSKSSLSGQHGRERTQASAEGCKE--GRERREKDRALGRSSHRRRTGESRHKTRG-- 451
            S+ +   S SGQ  R     S+ G     G+      ++LG   H   +G+S   +RG  
Sbjct: 2365 SSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 2424

Query: 452  DKIAQKSSSRSSFSHRANRDDKK---EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKS 508
               + +SSS S +   +     +   E G G+     HR+S  G S       S + H S
Sbjct: 2425 GSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2484

Query: 509  GRSLWTTSSGSSKGLGR 525
                  ++SG S   G+
Sbjct: 2485 THGQHGSTSGQSSSCGQ 2501



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 54/215 (25%), Positives = 80/215 (37%), Gaps = 18/215 (8%)

Query: 321  GGNKGNMALAGT-ASMAPNSTKVAVAGAA-GKSSEHV-----SSASMSLSREGSVSLAIA 373
            G + G+ +  G   S +  S+     GA+ G+SS H      SS S    R+GS S    
Sbjct: 2477 GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 2536

Query: 374  GVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRAL 433
            G       + ++      G    +   +SS SGQHG    ++S  G  E    +    + 
Sbjct: 2537 GHGQRGSGSRQSPSYGRHG----SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 2592

Query: 434  GRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGV 493
              S     +G  +H   G +  Q S      S   +     + G G+  SS H     G 
Sbjct: 2593 HGSGSGHSSGYGQH---GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS 2649

Query: 494  SHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSS 528
              +P    SR  H SG    ++      G GR SS
Sbjct: 2650 GQSP----SRGRHGSGLGHSSSHGQHGSGSGRSSS 2680



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 57/219 (26%), Positives = 86/219 (39%), Gaps = 26/219 (11%)

Query: 321  GGNKGNMALAGT-ASMAPNSTKVAVAGAA-GKSSEHV-----SSASMSLSREGSVSLAIA 373
            G + G+ +  G   S +  S+     GA+ G+SS H      SS S    R+GS S    
Sbjct: 1537 GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 1596

Query: 374  GVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRAL 433
            G       + ++      G    +   +SS SGQHG    ++S  G  E    +    + 
Sbjct: 1597 GHGQRGSGSRQSPSYGRHG----SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 1652

Query: 434  GRSSHRRRTGESRHKTRGDKIAQ----KSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDS 489
              S     +G  +H +R  + ++     SSSRSS  +        + G G+  SS H   
Sbjct: 1653 HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRY-------GQHGSGSRQSSGHGRQ 1705

Query: 490  HKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSS 528
              G   +P    SR  H SG    ++      G GR SS
Sbjct: 1706 GSGSGQSP----SRGRHGSGLGHSSSHGQHGSGSGRSSS 1740



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 9/134 (6%)

Query: 397  TRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQ 456
            +R  +SS   QHG     +S+ G + G   R+   +LG   H   +G+S   +RG   + 
Sbjct: 1902 SRSGQSSRGEQHGSSSGSSSSYG-QHGSGSRQ---SLGHGQHGSGSGQSPSPSRGRHGSG 1957

Query: 457  KSSSRS-----SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511
               S S     S S  ++     E G G+     HR+S  G S       S + H S   
Sbjct: 1958 SGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 2017

Query: 512  LWTTSSGSSKGLGR 525
               ++SG S   G+
Sbjct: 2018 QHGSASGQSSSCGQ 2031



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 62/277 (22%), Positives = 98/277 (35%), Gaps = 25/277 (9%)

Query: 274  GIKEAAAAGAAAGAATGTVAGAL-SVAAANSAPGQVSA-----AIAGAATIDAGGNKGNM 327
            G  E+ +  ++A +  G+ +G   S     S  GQ S      +  G ++       G+ 
Sbjct: 1285 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSS 1344

Query: 328  ALAGTASMAPNSTKVAVAGAAGKSSEHVSSA---------SMSLSREGSVSLAIAGV--- 375
              +G       S +    G  G  S H SS          S S  R GS S   +G    
Sbjct: 1345 QSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1404

Query: 376  VLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKE--GRERREKDRAL 433
              +S  ++      +     S+ +   S SGQ  R     S+ G     G+      ++L
Sbjct: 1405 ESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSL 1464

Query: 434  GRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSR-----HRD 488
            G   H   +G+S   +RG   +    S S   + +       +G    GSS      HR+
Sbjct: 1465 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRE 1524

Query: 489  SHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGR 525
            S  G S       S + H S      ++SG S   G+
Sbjct: 1525 SRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQ 1561



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 38/146 (26%), Positives = 55/146 (37%), Gaps = 23/146 (15%)

Query: 401  KSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESR-HKTRGDKIAQKSS 459
            +SS SG+HG    Q+S  G K         ++ G + H   +G S  ++  G +  Q S 
Sbjct: 915  RSSSSGRHGSGSGQSSGFGHKSS-----SGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 969

Query: 460  SRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSL------- 512
            S    S   +     + G G+  S  H     G   +P     R    SG+S        
Sbjct: 970  SEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRS 1029

Query: 513  ---WTTS-------SGSSKGLGRVSS 528
               W++S       SG S GLG   S
Sbjct: 1030 GSGWSSSRGPYESGSGHSSGLGHRES 1055



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 44/186 (23%), Positives = 68/186 (36%), Gaps = 20/186 (10%)

Query: 345 AGAAGKSSEHVSSA--SMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKS 402
           +G + +   H SS+  S S  + GS S    G       + ++      G    +    S
Sbjct: 264 SGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHG----SGSGHS 319

Query: 403 SLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRS 462
           S  GQHG   + + + G  E    +        S   + +G S+H +         S  S
Sbjct: 320 SSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGS--------GSGHS 371

Query: 463 SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKG 522
           S   +      +    G  GSS  + S  G        ES + H SGR   ++ SG S G
Sbjct: 372 SSQGQHGSTSGQASSSGQHGSSSRQSSSYG------QHESASRHSSGRGQHSSGSGQSPG 425

Query: 523 LGRVSS 528
            G+  S
Sbjct: 426 HGQRGS 431



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 48/204 (23%), Positives = 76/204 (37%), Gaps = 20/204 (9%)

Query: 330 AGTASMAPNSTKVAVAGAAGKSSEHVSSASMS--LSREGSVSLAIAGVVLTSRTAAEADM 387
           +G+   + N T  + +G +   S+H SS+  S   S+ GS S   +G       + ++  
Sbjct: 210 SGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQS-- 267

Query: 388 DAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRH 447
             + G    +    SS  GQHG    Q+   G ++G   R+        SH R    S H
Sbjct: 268 --SRGERHRSSSGSSSSYGQHGSGSRQSLGHG-RQGSGSRQSP------SHVRHGSGSGH 318

Query: 448 KTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHK 507
            +   +    SS   S  H        E G G        +S  G S       S + H 
Sbjct: 319 SSSHGQHGSGSSYSYSRGHY-------ESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHS 371

Query: 508 SGRSLWTTSSGSSKGLGRVSSFLR 531
           S +    ++SG +   G+  S  R
Sbjct: 372 SSQGQHGSTSGQASSSGQHGSSSR 395



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 45/184 (24%), Positives = 66/184 (35%), Gaps = 16/184 (8%)

Query: 353  EHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRER 412
            E  S  S S S+ GS S   +G       + ++      G    +    SS  GQHG   
Sbjct: 1171 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG----SSSGSSSHYGQHGSGS 1226

Query: 413  TQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDD 472
             Q+S  G    R+      +  R  H    G S    +    + +SSSR  +  R+    
Sbjct: 1227 RQSSGHG----RQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSS 1282

Query: 473  ---KKEKGCGNPGSSRHRDSHKG-----VSHTPISKESRTSHKSGRSLWTTSSGSSKGLG 524
               + E G G+  +     S  G       H   S +S T  + G S   +SS   +G G
Sbjct: 1283 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSG 1342

Query: 525  RVSS 528
               S
Sbjct: 1343 SSQS 1346



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 45/184 (24%), Positives = 66/184 (35%), Gaps = 16/184 (8%)

Query: 353  EHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRER 412
            E  S  S S S+ GS S   +G       + ++      G    +    SS  GQHG   
Sbjct: 1641 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG----SSSRSSSRYGQHGSGS 1696

Query: 413  TQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDD 472
             Q+S  G    R+     ++  R  H    G S    +    + +SSSR  +  R+    
Sbjct: 1697 RQSSGHG----RQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSS 1752

Query: 473  ---KKEKGCGNPGSSRHRDSHKG-----VSHTPISKESRTSHKSGRSLWTTSSGSSKGLG 524
               + E G G+  +     S  G       H   S +S T  + G S   +SS    G G
Sbjct: 1753 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSG 1812

Query: 525  RVSS 528
               S
Sbjct: 1813 SSQS 1816



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 45/184 (24%), Positives = 66/184 (35%), Gaps = 16/184 (8%)

Query: 353  EHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRER 412
            E  S  S S S+ GS S   +G       + ++      G    +    SS  GQHG   
Sbjct: 2581 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG----SSSGSSSHYGQHGSGS 2636

Query: 413  TQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDD 472
             Q+S  G    R+     ++  R  H    G S    +    + +SSSR  +  R     
Sbjct: 2637 RQSSGHG----RQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSS 2692

Query: 473  ---KKEKGCGNPGSSRHRDSHKG-----VSHTPISKESRTSHKSGRSLWTTSSGSSKGLG 524
               + E G G+  +     S  G       H   S +S T  + G S   +SS   +G G
Sbjct: 2693 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSG 2752

Query: 525  RVSS 528
               S
Sbjct: 2753 SSQS 2756



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 43/157 (27%), Positives = 63/157 (40%), Gaps = 33/157 (21%)

Query: 402  SSLSGQHGRERTQASAEGCKEGRERR-----EKDRALGRSS----HRRRTGESRHKTRGD 452
            SS SG+HG    Q+S  G  E    +     +     G SS    H  R+G+S   +RG+
Sbjct: 1385 SSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQS---SRGE 1441

Query: 453  KIAQKSSSRSSFSHRANRDDKK----EKGCGN-----PGSSRHRD-SHKGVSHTPISK-- 500
            +    S S SS+    +   +     + G G+     P   RH   S +  S++P     
Sbjct: 1442 RHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS 1501

Query: 501  ---------ESRTSHKSGRSLWTTSSGSSKGLGRVSS 528
                     ES +SH SG     + SG S G G+  S
Sbjct: 1502 GWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGS 1538



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 56/238 (23%), Positives = 84/238 (35%), Gaps = 43/238 (18%)

Query: 321  GGNKGNMALAGT--ASMAPNSTKVAVAGAAGKSSEHV-----SSASMSLSREGSVSLAIA 373
            G   G+    G   ++   +ST      + G+SS H      SS S S  ++GS S    
Sbjct: 1771 GSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS---- 1826

Query: 374  GVVLTSRTAAEADMDAAAGPPVSTRQSKS-----SLSGQHGRERTQASAEGCKEGRERRE 428
                  ++ +     + +G   S  Q  S     S SG+HG    Q+S  G  E    + 
Sbjct: 1827 -----GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS 1881

Query: 429  KDRALGRSSHRRRTGESR-HKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHR 487
                 G + H   +G S  ++  G +  Q S      S   +     + G G+  S  H 
Sbjct: 1882 S----GYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHG 1937

Query: 488  DSHKGVSHTPISKESRTSHKSGRSL----------WTTS-------SGSSKGLGRVSS 528
                G   +P     R    SG+S           W++S       SG S GLG   S
Sbjct: 1938 QHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRES 1995



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 61/250 (24%), Positives = 94/250 (37%), Gaps = 54/250 (21%)

Query: 321  GGNKGNMALAGT--ASMAPNSTKVAVAGAAGKSSEHV-----SSASMSLSREGSVSLAIA 373
            G   G+    G   ++   +ST      + G+SS H      SS S S  ++GS S    
Sbjct: 2241 GSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS---- 2296

Query: 374  GVVLTSRTAAEADMDAAAGPPVSTRQSKS-----SLSGQHGRERTQASAEGCKEGRERR- 427
                  ++ +     + +G   S  Q  S     S SG+HG    Q+S  G  E    + 
Sbjct: 2297 -----GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS 2351

Query: 428  ----EKDRALGRSS----HRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKK----E 475
                +     G SS    H  R+G+S   +RG++    S S SS+    +   +     +
Sbjct: 2352 SGYTQHGSGSGHSSSYEQHGSRSGQS---SRGERHGSSSGSSSSYGQHGSGSRQSLGHGQ 2408

Query: 476  KGCGN-----PGSSRHRD-SHKGVSHTPISK-----------ESRTSHKSGRSLWTTSSG 518
             G G+     P   RH   S +  S++P              ES + H SG     + SG
Sbjct: 2409 HGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSG 2468

Query: 519  SSKGLGRVSS 528
             S G G+  S
Sbjct: 2469 QSSGYGQHGS 2478



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 46/181 (25%), Positives = 63/181 (34%), Gaps = 42/181 (23%)

Query: 345 AGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSL 404
           +G A    +H S +    S+ GS S            +++    + +G        +SS 
Sbjct: 811 SGQASGFGQHESGSGQGYSQHGSAS---------GHFSSQGRHGSTSG--------QSSS 853

Query: 405 SGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESR-HKTRGDKIAQKSSSRSS 463
           SGQH     Q+S+ G  E         A GR  H   +G+S  H  RG    Q  S    
Sbjct: 854 SGQHDSSSGQSSSYGQHESASHH----ASGRGRHGSGSGQSPGHGQRGSGSGQSPSY--- 906

Query: 464 FSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHK--SGRSLWTTSSGSSK 521
                          G  GS   R S  G   +   + S   HK  SG+S   T  GS  
Sbjct: 907 ---------------GRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGS 951

Query: 522 G 522
           G
Sbjct: 952 G 952



 Score = 33.5 bits (75), Expect = 0.57
 Identities = 51/211 (24%), Positives = 73/211 (34%), Gaps = 44/211 (20%)

Query: 345 AGAAGKSSEHVSSASMSL--SREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKS 402
           AG++    +H S +  SL  SR GS S              ++   +       +RQS S
Sbjct: 511 AGSSSSYGQHGSGSRQSLGHSRHGSGS-------------GQSPSPSRGRHESGSRQSSS 557

Query: 403 SLSGQHGRERTQASAEGCKE---------GRERREKDRALGRSSHRRRTGESR-HKTRGD 452
              G HG    ++S+ G  E         G +     ++ G   H   +G S  H   G 
Sbjct: 558 Y--GPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGS 615

Query: 453 KIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPI---------SKESR 503
              Q SS     +         + G G+  SSR+     G   +P             S 
Sbjct: 616 TSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSY 675

Query: 504 TSHKSGRSLWTTS-------SGSSKGLGRVS 527
             H SG S W++S       SG S G G  S
Sbjct: 676 GQHGSG-SGWSSSNGPHGSVSGQSSGFGHKS 705



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 54/256 (21%), Positives = 89/256 (34%), Gaps = 12/256 (4%)

Query: 274  GIKEAAAAGAAAGAATGTVAGALSVAAAN-SAPGQVSA-----AIAGAATIDAGGNKGNM 327
            G +E+ +  ++     G+ +G  S    + SA GQ S+     A +G ++       G+ 
Sbjct: 1991 GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSS 2050

Query: 328  ALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADM 387
              +G       S +    G  G  S    S     S  G  S +         ++     
Sbjct: 2051 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHH 2110

Query: 388  DAAAGPPVSTRQ-----SKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRT 442
            ++++G   S  Q       SS  GQHG  R+  S+ G + G       R     S  R++
Sbjct: 2111 ESSSGQSSSYSQHGSGSGHSSGYGQHG-SRSGQSSRGERHGSSSGSSSRYGQHGSGSRQS 2169

Query: 443  GESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKES 502
                 +  G   +       S S  ++   +   G G   S    +S  G S      ES
Sbjct: 2170 SGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHES 2229

Query: 503  RTSHKSGRSLWTTSSG 518
             + H S  S   + SG
Sbjct: 2230 GSGHSSAYSQHGSGSG 2245


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 45/173 (26%), Positives = 76/173 (43%), Gaps = 16/173 (9%)

Query: 350 KSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEA-----DMDAAAGPPVSTRQSKSSL 404
           ++S+H  S S S SRE        G    SR+ ++        D ++    S   +    
Sbjct: 34  RASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEH 93

Query: 405 SGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRG---------DKIA 455
           S   GRER  +S  G ++  +R+E+  + GRS  R R+ E RH++R           +  
Sbjct: 94  SSDKGRERLNSSENG-EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRER 152

Query: 456 QKSSSRSSFSHRA-NRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHK 507
           +KS SRS    ++ +R  ++++   +   SR R  H+  S +     SR   K
Sbjct: 153 KKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKK 205



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 28/151 (18%)

Query: 398 RQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGR-----------SSHRRR----- 441
           R+ KS   G+  R R+++     KEGR    KD++  +           SS + R     
Sbjct: 50  RKRKSDNEGRKHRSRSRS-----KEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNS 104

Query: 442 --TGESRHKTRGDKIAQ-KSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPI 498
              GE RHK +  K ++ +S SRS    R +R   +E+       SR R+  K  S +  
Sbjct: 105 SENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRER---KKSRSRSRERKKSRSRSRE 161

Query: 499 SKESRT-SHKSGRSLWTTSSGSSKGLGRVSS 528
            K+SR+ S +  R + + S   S+   R  S
Sbjct: 162 RKKSRSRSRERKRRIRSRSRSRSRHRHRTRS 192


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 77/334 (23%), Positives = 128/334 (38%), Gaps = 57/334 (17%)

Query: 281  AGAAAGAATGT---VAGALSVAAANSAPGQVSAAIAGAATIDAG--GNKGNMALAGTASM 335
            A ++AG   G+   +  A S   + +  GQ S+A+      D+G  G+ G+ A       
Sbjct: 700  ARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVR-----DSGHRGSSGSQATDSEGHS 754

Query: 336  APNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAA-AGPP 394
              + T+ +V+G         S    +  R G  S      +    T  +++      GP 
Sbjct: 755  EDSDTQ-SVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPS 813

Query: 395  VSTRQ----------SKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGE 444
               RQ          S+ S S Q G++  +      + GR+    ++++ RS H   +  
Sbjct: 814  TGVRQGSHHEQARDNSRHSAS-QDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGH-SGSHH 871

Query: 445  SRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKE--- 501
            S   ++G   A +  S S  + R  R++++ +       SRH   H+  SH  IS+    
Sbjct: 872  SHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRH---HEASSHADISRHSQA 928

Query: 502  -------SRTSHKSGRSLW--TTSSGSSKGLGRVS-SFLRNVRANLTTK----------- 540
                   SRTS + G S+   + S G S+   R S S  RN R +   +           
Sbjct: 929  GQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSH 988

Query: 541  -VVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQ 573
                  HG   D     + R +    AET+ GGQ
Sbjct: 989  HEDRAGHGHSAD-----SSRQSGTPHAETSSGGQ 1017



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 52/234 (22%), Positives = 94/234 (40%), Gaps = 22/234 (9%)

Query: 276  KEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASM 335
            +++ +A   AG +TG   G+    A +S+  + SA+  G  TI   G+ G+    G    
Sbjct: 3718 EQSESAHGRAGPSTGGRQGSRHEQARDSS--RHSASQEGQDTIR--GHPGSRR--GGRQG 3771

Query: 336  APNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPV 395
            + +   V  +G +G    H +S   S +  G      +G    SR     +         
Sbjct: 3772 SYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQ-----SGSRSASRETRNEEQSGDGSRHS 3826

Query: 396  STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
             +R  ++S      R       E     R RR+     G S  +    E+  +      +
Sbjct: 3827 GSRHHEASTQADSSRHSQSGQGESAGSRRSRRQ-----GSSVSQDSDSEAYPED-----S 3876

Query: 456  QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSG 509
            ++ S  +S +H  +  ++   G  +PGSS HRD+   V  +P+  +S T+ + G
Sbjct: 3877 ERRSESASRNHHGSSREQSRDGSRHPGSS-HRDTASHVQSSPVQSDSSTAKEHG 3929



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 46/204 (22%), Positives = 73/204 (35%), Gaps = 19/204 (9%)

Query: 317  TIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSS---EHVSSASMSLSREGSVSLAIA 373
            T   G +  +   +G+ S +  +     +G   + S    H +S    +SR    S A+ 
Sbjct: 2819 TTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRH---SQAVQ 2875

Query: 374  GVVLTSR------TAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERR 427
            G    SR      ++   D D+      S R S S+    HG  + Q   +G +  R  +
Sbjct: 2876 GQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLR-DGSRHPRSHQ 2934

Query: 428  EKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHR 487
            E     G S+   R   +RH          S  +++ SH   R    E+   +   S   
Sbjct: 2935 EDRAGHGHSADSSRQSGTRHTQTS------SGGQAASSHEQARSSAGERHGSHHQQSADS 2988

Query: 488  DSHKGVSHTPISKESRTSHKSGRS 511
              H G+ H   S   R S   G S
Sbjct: 2989 SRHSGIGHGQASSAVRDSGHRGYS 3012



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 41/170 (24%), Positives = 57/170 (33%), Gaps = 21/170 (12%)

Query: 351 SSEHVSSASMSLSREGSVSLAIAGVVLTSR---TAAEADMDAAAGPPVSTRQSKSSLSGQ 407
           S  H +S+    SR   V    +    TSR   ++   D D+      S R S S+    
Sbjct: 586 SRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNH 645

Query: 408 HGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHR 467
           HG  + Q S +G +  R           S H  R G         K   + +  SS    
Sbjct: 646 HGSAQEQ-SRDGSRHPR-----------SHHEDRAGHGHSADSSRKSGTRHTQNSSSGQA 693

Query: 468 ANRDDKKEKGCGNPGSSRHR------DSHKGVSHTPISKESRTSHKSGRS 511
           A+  ++     G    SRH+        H G  H   S   R S   G S
Sbjct: 694 ASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSS 743



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 50/196 (25%), Positives = 72/196 (36%), Gaps = 13/196 (6%)

Query: 332  TASMAPNSTKVAVAGAAGKSSEHVSSASMS-LSREGSVSLAIAGVVLTSR---TAAEADM 387
            +AS      K +  G+    S H  +AS +  SR   V    +    TSR   ++   D 
Sbjct: 1215 SASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDS 1274

Query: 388  DAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRH 447
            D+      S R S S+    HG  R Q S +G +     +E   + G S+   R   + H
Sbjct: 1275 DSERHSDDSERLSGSASRNHHGSSREQ-SRDGSRHPGFHQEDRASHGHSADSSRQSGTHH 1333

Query: 448  KTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTS-H 506
                      S  ++  SH   R    E+       S     H G+ H   S   R S H
Sbjct: 1334 TE------SSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGH 1387

Query: 507  K-SGRSLWTTSSGSSK 521
            + S  S  T S G S+
Sbjct: 1388 RGSSGSQVTNSEGHSE 1403



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 55/276 (19%), Positives = 105/276 (38%), Gaps = 24/276 (8%)

Query: 265 ELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIA--------GAA 316
           E +    T    E A +       +G    A S   + +  GQ S+A++        G+ 
Sbjct: 362 ETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQ 421

Query: 317 TIDAGGNKGN-----MALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLA 371
             D+ G+  N     ++  G A +   S + +  G +G+ S    S+   +S       A
Sbjct: 422 ASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSA 481

Query: 372 IAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDR 431
             G   TS    +      A      R S    + Q G++  +      + GR+    ++
Sbjct: 482 -HGRTGTSTGGRQGSHHEQA------RDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQ 534

Query: 432 ALGRSSHR-RRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSH 490
           ++ RS H       +  + R D    +S SRS+ S +   +++   G  + GS  H  S 
Sbjct: 535 SVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSA-SRQTRNEEQSGDGTRHSGSRHHEASS 593

Query: 491 KGVS--HTPISKESRTSHKSGRSLWTTSSGSSKGLG 524
           +  S  H+ + +   +  ++ R+  ++ S  S   G
Sbjct: 594 QADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQG 629



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 83/351 (23%), Positives = 136/351 (38%), Gaps = 66/351 (18%)

Query: 269  EPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAP------GQVSAAIA-----GAAT 317
            E ++GG  +AA++   A ++ G   G+    +A+S+       GQ S+A+      G++ 
Sbjct: 3280 ETSSGG--QAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSG 3337

Query: 318  IDAGGNKGNMALAGTASMAPNSTKVAVAGAAG--KSSEHVSSASMSLSREGSVSLAIAGV 375
              A  ++G+   + T S++ +       G AG  + S   S+   S  R G      +G 
Sbjct: 3338 SQASDSEGHSEESDTQSVSGH-------GQAGPHQQSHQESARDRSGGRSGR-----SGS 3385

Query: 376  VLTSRTAAEADMDAAAGPPVST-----------RQSKSSLSGQHGRERTQASAEGCKEGR 424
             L   +  E    A      ST           R S    + Q G++  +      + GR
Sbjct: 3386 FLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGR 3445

Query: 425  ERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKK---------- 474
            +    ++++ RS H   +  S   ++G   A +  S S  + R  R+D++          
Sbjct: 3446 QGSHYEQSVDRSGH-SGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWS 3504

Query: 475  --EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLW--TTSSGSSKGLGRVS-SF 529
               +      SSRH  S +G S  P     RTS   G S+   + S G S+   R S S 
Sbjct: 3505 HHHEASTQADSSRHSQSGQGQSAGP-----RTSRNQGSSVSQDSDSQGHSEDSERWSGSA 3559

Query: 530  LRNVRANLTTKVVG-----TPHGRDVDVMAKMAE--RSTNVAIAETAEGGQ 573
             RN R +   +        T H  D       AE  R +    AE + GGQ
Sbjct: 3560 SRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQ 3610



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 59/265 (22%), Positives = 104/265 (39%), Gaps = 26/265 (9%)

Query: 269  EPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQ-VSAAIAGAATIDAG--GNKG 325
            E ++GG  +AA++   A ++ G   G+    +A+S+    +    A +A  D+G  G+ G
Sbjct: 1011 ETSSGG--QAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSG 1068

Query: 326  NMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEA 385
            + A         + T+ +V+G  G+   H  S   S           +G  +   +  E 
Sbjct: 1069 SQASDSEGHSEESDTQ-SVSGH-GQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQ 1126

Query: 386  DMDAAAGPPVST-----------RQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALG 434
               A      ST           R S    + Q G++  +A     + GR+    ++++ 
Sbjct: 1127 SESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVD 1186

Query: 435  RSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVS 494
            RS H   +  S   ++G   A    S S  + R  R DK+         SRH ++     
Sbjct: 1187 RSGH-SGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWAD 1245

Query: 495  ---HTPISKE----SRTSHKSGRSL 512
               H+ + +E    SRTS   G S+
Sbjct: 1246 SSRHSQVGQEQSSGSRTSRHQGSSV 1270



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 39/164 (23%), Positives = 58/164 (35%), Gaps = 10/164 (6%)

Query: 351  SSEHVSSASMSLSREGSVSLAIAGVVLTSR---TAAEADMDAAAGPPVSTRQSKSSLSGQ 407
            S  H +S+    S    V    +    TSR   ++   D D+      S R S S+    
Sbjct: 2532 SRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNH 2591

Query: 408  HGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHR 467
            HG  + Q   +G +  R  +E     G S+   R   +RH          S  +++ SH 
Sbjct: 2592 HGSAQEQLR-DGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTS------SGGQAASSHE 2644

Query: 468  ANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511
              R    E+   +   S     H G+ H   S   R S   G S
Sbjct: 2645 QARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYS 2688



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 38/172 (22%), Positives = 66/172 (38%), Gaps = 20/172 (11%)

Query: 346  GAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLS 405
            G+A + S H S    S  +E   S   +           A+  +      S  Q++SS  
Sbjct: 1620 GSAREQSRHGSRNPRS-HQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPG 1678

Query: 406  GQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFS 465
             +HG    Q++      G  RR+    +G S +R  +G     + G   +++S ++S  +
Sbjct: 1679 ERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGH--SEESDTQSVSA 1736

Query: 466  HRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSS 517
            H          G   P    H++S +G S          S +SG  L+  S+
Sbjct: 1737 H----------GQAGPHQQSHQESTRGQS-------GERSGRSGSFLYQVST 1771



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 40/169 (23%), Positives = 58/169 (34%), Gaps = 20/169 (11%)

Query: 351  SSEHVSSASMSLSREGSVSLAIAGVVLTSR---TAAEADMDAAAGPPVSTRQSKSSLSGQ 407
            S  H +S+    SR   V    +    TSR   ++   D D+      S R+S S+    
Sbjct: 2208 SHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNH 2267

Query: 408  HGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHR 467
            HG  + Q S +G +  R           S H  R G         +     +  SS    
Sbjct: 2268 HGSAQEQ-SRDGSRHPR-----------SHHEDRAGHGHSAESSRQSGTHHAENSSGGQA 2315

Query: 468  ANRDDKKEKGCGNPGSSRHRDS-----HKGVSHTPISKESRTSHKSGRS 511
            A+  ++     G    S H+ S     H G+ H   S   R S   G S
Sbjct: 2316 ASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSS 2364



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 41/167 (24%), Positives = 58/167 (34%), Gaps = 15/167 (8%)

Query: 351  SSEHVSSASMSLSREGSVSLAIAGVVLTSR---TAAEADMDAAAGPPVSTRQSKSSLSGQ 407
            S  H +S+    SR   V    +    TSR   ++   D D+      S R S S+ S  
Sbjct: 1883 SRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSA-SRN 1941

Query: 408  HGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRH---KTRGDKIAQKSSSRSSF 464
            H     + S +G +      E     G S+   R   +RH    +RG   +    +RSS 
Sbjct: 1942 HLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSA 2001

Query: 465  SHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511
              R         G  +   S     H G+ H   S   R S   G S
Sbjct: 2002 GER--------HGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYS 2040



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 34/143 (23%), Positives = 49/143 (34%), Gaps = 15/143 (10%)

Query: 383  AEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRT 442
            +++    +AGP  S  Q  SS+S     +     +E       R  +  A  +S    R 
Sbjct: 3519 SQSGQGQSAGPRTSRNQG-SSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRH 3577

Query: 443  GESRHKTRGDKIAQKSSSRSSFSHRANRD---------DKKEKGCGNPGSSRHRDS---- 489
              S H+ R        SSR S +H A            ++     G    S H+ S    
Sbjct: 3578 PTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSS 3637

Query: 490  -HKGVSHTPISKESRTSHKSGRS 511
             H G+ H   S   R S   G S
Sbjct: 3638 RHSGIGHGQASSAVRDSGHRGSS 3660



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 46/208 (22%), Positives = 71/208 (34%), Gaps = 17/208 (8%)

Query: 317  TIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSS---EHVSSASMSLSREGSVSLAIA 373
            T   G +  +   +G+ S +  +     +G + + S    H +S    +SR    S A+ 
Sbjct: 3143 TTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRH---SQAVQ 3199

Query: 374  GVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEG--RERREKDR 431
            G    SR +             S  Q   S       ER   SA     G  +E+     
Sbjct: 3200 GQSEGSRRSRRQGS--------SVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGS 3251

Query: 432  ALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHK 491
               RS H  R G      R  +   + +  SS    A+  ++     G    SRH+ S  
Sbjct: 3252 RHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSAD 3311

Query: 492  GVSHTPISKESRTSHKSGRSLWTTSSGS 519
               H+ I +   +S       W  SSGS
Sbjct: 3312 SSRHSGIPRGQASSAVRDSRHW-GSSGS 3338



 Score = 32.7 bits (73), Expect = 0.97
 Identities = 24/112 (21%), Positives = 41/112 (36%), Gaps = 1/112 (0%)

Query: 396 STRQSKSSLSGQHGRERTQASAEGCKE-GRERREKDRALGRSSHRRRTGESRHKTRGDKI 454
           S  Q++SS   +HG      SA+  +  G    +   A+  S HR  +G     + G   
Sbjct: 696 SHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSE 755

Query: 455 AQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSH 506
              + S S      +     ++   +    R R S   +      K+S +SH
Sbjct: 756 DSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSH 807



 Score = 32.7 bits (73), Expect = 0.97
 Identities = 45/215 (20%), Positives = 78/215 (36%), Gaps = 17/215 (7%)

Query: 317  TIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVV 376
            ++D  G+ G+     T+    ++++    G +G  S   ++ +   SR+GS         
Sbjct: 860  SVDRSGHSGSHHSHTTSQGRSDASR----GQSGSRSASRTTRNEEQSRDGSRHSGSRHHE 915

Query: 377  LTSRTA----AEADMDAAAGPPVSTRQ----SKSSLSGQHGRERTQASAEGCKEGRERRE 428
             +S       ++A    + G   S RQ    S+ S S  H  +  + S    +  R   +
Sbjct: 916  ASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQ 975

Query: 429  KDRALG----RSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSS 484
            +    G    RS H  R G         +     +  SS    A+  ++     G    S
Sbjct: 976  EQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGS 1035

Query: 485  RHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGS 519
            RH+ S     H+ I +   +S       W  SSGS
Sbjct: 1036 RHQQSADSSRHSGIPRRQASSAVRDSGHW-GSSGS 1069



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 28/127 (22%), Positives = 50/127 (39%), Gaps = 4/127 (3%)

Query: 396  STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
            S  Q++SS   +HG    Q++      G    +   A+  S HR  +G     + G   +
Sbjct: 2318 SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGH--S 2375

Query: 456  QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTT 515
            + S ++S  +H      ++       G S  R    G     +S   ++    GR+   T
Sbjct: 2376 EDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRT--GT 2433

Query: 516  SSGSSKG 522
            S+G  +G
Sbjct: 2434 STGGRQG 2440



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 38/145 (26%), Positives = 52/145 (35%), Gaps = 14/145 (9%)

Query: 390  AAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKT 449
            +AG   S RQ  SS+S     E     +E   E   R     A  +S H  R   S  + 
Sbjct: 1581 SAGSKTSRRQG-SSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQED 1639

Query: 450  RGDKIAQKSSSRSSFSHRANRD------DKKEKGCGNPGSSRHRDSHKGVSHTPISKESR 503
            R        SSR S +  A           +E+   +PG  RH   H+       S +S 
Sbjct: 1640 RASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPG-ERHGSRHQQ------SADSS 1692

Query: 504  TSHKSGRSLWTTSSGSSKGLGRVSS 528
            T   +GR   ++  G S   G   S
Sbjct: 1693 TDSGTGRRQDSSVVGDSGNRGSSGS 1717



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 19/123 (15%)

Query: 396 STRQSKSSLSGQHGRERTQASAEGC---KEGRERREKDRAL----------GRSSHRRRT 442
           STR+    +SG   R+ +          +E +E R++  +L          GRS   R T
Sbjct: 88  STRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRET 147

Query: 443 GESRHKTRGDKIAQKSSS----RSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPI 498
           G  RH++  +K  +K  S       +    +   KKEK      ++R  D+ K +S    
Sbjct: 148 GGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEK--NKTENTRLGDNRKRLSERLE 205

Query: 499 SKE 501
            KE
Sbjct: 206 EKE 208



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 27/133 (20%), Positives = 46/133 (34%)

Query: 396  STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
            S  Q++SS   +HG    Q++      G  RR+   A+  S H   +G     + G    
Sbjct: 1021 SHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEE 1080

Query: 456  QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTT 515
              + S S            ++   +    R   S   +      ++S ++H   R+    
Sbjct: 1081 SDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGR 1140

Query: 516  SSGSSKGLGRVSS 528
              GS     R SS
Sbjct: 1141 RQGSHHEQARDSS 1153



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 12/99 (12%)

Query: 396  STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
            S  Q++SS   +HG    Q++      G   R+   A+  S HR  +G     + G   +
Sbjct: 1345 SHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGH--S 1402

Query: 456  QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVS 494
            + S ++S  +H          G   P    H++S +G S
Sbjct: 1403 EDSDTQSVSAH----------GQAGPHQQSHKESARGQS 1431



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 22/116 (18%)

Query: 396  STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
            S  Q++SS   +HG    Q++      G    +   A+  S HR  +G     + G   +
Sbjct: 3614 SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGH--S 3671

Query: 456  QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511
            + S ++S  +H          G   P    H++S +G          R++ +SGRS
Sbjct: 3672 EDSDTQSVSAH----------GQAGPHQQSHQESTRG----------RSAGRSGRS 3707



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 33/177 (18%), Positives = 63/177 (35%), Gaps = 6/177 (3%)

Query: 317  TIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSS---EHVSSASMSLSREGSVSLAIA 373
            T   G +  +   +G+ S +  +     +G   + S    H +S     SR        +
Sbjct: 3791 TTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGES 3850

Query: 374  GVVLTSR---TAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKD 430
                 SR   ++   D D+ A P  S R+S+S+    HG  R Q+       G   R+  
Sbjct: 3851 AGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTA 3910

Query: 431  RALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHR 487
              +  S  +  +  ++       ++Q S+  S    R +          + G+ R +
Sbjct: 3911 SHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQK 3967



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 28/122 (22%), Positives = 44/122 (36%), Gaps = 19/122 (15%)

Query: 396  STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
            S  Q++SS   +HG    Q++      G    +   A+  S HR  +G       G    
Sbjct: 2642 SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEG---- 2697

Query: 456  QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTT 515
                      H  + D +     G  GS  H+ SH+    +   +   TS  SG  L+  
Sbjct: 2698 ----------HSEDSDTQSVSAHGQAGS--HQQSHQ---ESARGRSGETSGHSGSFLYQV 2742

Query: 516  SS 517
            S+
Sbjct: 2743 ST 2744



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 28/122 (22%), Positives = 44/122 (36%), Gaps = 19/122 (15%)

Query: 396  STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
            S  Q++SS   +HG    Q++      G    +   A+  S HR  +G       G    
Sbjct: 2966 SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEG---- 3021

Query: 456  QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTT 515
                      H  + D +     G  GS  H+ SH+    +   +   TS  SG  L+  
Sbjct: 3022 ----------HSEDSDTQSVSAHGQAGS--HQQSHQ---ESARGRSGETSGHSGSFLYQV 3066

Query: 516  SS 517
            S+
Sbjct: 3067 ST 3068


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 61/237 (25%), Positives = 96/237 (40%), Gaps = 33/237 (13%)

Query: 279 AAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPN 338
           A A A AG   G   G L      +  G V  A  GA T+D       +A  G      N
Sbjct: 126 APANAVAGLLPG--GGLLPTPNPLTQIGAVPLAALGAPTLDPA-----LAALGLPGANLN 178

Query: 339 STKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTR 398
           S  +A    A +  + +S+    L+    V+  +    L S T+++   +A        R
Sbjct: 179 SQSLA----ADQLLKLMSTVDPKLNH---VAAGLVSPSLKSDTSSKEIEEAMK----RVR 227

Query: 399 QSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKS 458
           +++S +S         A+ E  K+  E+R   R+  RS  RR    SRH+    +  ++S
Sbjct: 228 EAQSLIS---------AAIEPDKK-EEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRS 277

Query: 459 SSRS-----SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR 510
            S+S     S S R  R   +E+G  +  +S+ RD  K       SK    S+ + R
Sbjct: 278 HSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTAR 334



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 30/136 (22%), Positives = 52/136 (38%), Gaps = 19/136 (13%)

Query: 396 STRQSKSSLSGQ-HGRER------TQASAEGCKEGRERRE------------KDRALGRS 436
           S R+SKS    + H RER      T  + +  KE +E++             + R+  R 
Sbjct: 283 SRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRE 342

Query: 437 SHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHT 496
             RRR+       +  +  ++  SRS    R  ++ KK+K        R R + K     
Sbjct: 343 RRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSK 402

Query: 497 PISKESRTSHKSGRSL 512
              K+     +S + +
Sbjct: 403 DKEKDRERKSESDKDV 418


>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
          Length = 717

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 38/159 (23%), Positives = 67/159 (42%), Gaps = 20/159 (12%)

Query: 331 GTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAA 390
           G A    + ++   + ++  SS   SS+S S S  GS S + +    +S T+  +  D++
Sbjct: 564 GRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSS-SRSSSSSSSSTSGSSSRDSS 622

Query: 391 AGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTR 450
           +    S+     S    H R+R        +   +R+ +D +    SH+   G S   T+
Sbjct: 623 SSTSSSSESRSRSRGRGHNRDRKH------RRSVDRKRRDTSGLERSHKSSKGGSSRDTK 676

Query: 451 GDK-------------IAQKSSSRSSFSHRANRDDKKEK 476
           G K              + +S  RSS S R  + D+K+K
Sbjct: 677 GSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDK 715



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 44/157 (28%), Positives = 62/157 (39%), Gaps = 21/157 (13%)

Query: 356 SSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQA 415
           +  S S SR  S S + +     S T++ +   +++G   S   S SS S      R  +
Sbjct: 568 NKTSKSRSRSSSSSSSSS-----SSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSS 622

Query: 416 SAEGCKEGRERREKDRALGRS-SHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKK 474
           S+         R + R   R   HRR     R  T G + + KSS   S     +RD K 
Sbjct: 623 SSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGS-----SRDTKG 677

Query: 475 EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511
            K   N  S R R          IS+ SR+  +S RS
Sbjct: 678 SKD-KNSRSDRKRS---------ISESSRSGKRSSRS 704



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 13/116 (11%)

Query: 425 ERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSS 484
           E + K +   RS  R R   S+ ++R    +  SSS +S S  ++          + GSS
Sbjct: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSS---------SSSGSS 601

Query: 485 RHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTK 540
             R S    S T  S    +S  S  S  ++S   S+  GR  +  R  R ++  K
Sbjct: 602 SSRSSSSSSSSTSGS----SSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRK 653



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 29/121 (23%), Positives = 45/121 (37%), Gaps = 6/121 (4%)

Query: 408 HGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQ--KSSSRSSFS 465
           H   +++        GR R +  ++  RSS    +  S   +     +    SSSRSS S
Sbjct: 549 HPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSS 608

Query: 466 HRANR--DDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR--SLWTTSSGSSK 521
             ++      ++       SS  R   +G  H    K  R+  +  R  S    S  SSK
Sbjct: 609 SSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSK 668

Query: 522 G 522
           G
Sbjct: 669 G 669


>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
          Length = 450

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 40/133 (30%), Positives = 59/133 (44%), Gaps = 12/133 (9%)

Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455
           S+  S SS S     E +  S    KE + +R+K +    S H     E + K++  K+ 
Sbjct: 260 SSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLH 319

Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGV--SHTPISKESRT-SHKSGRSL 512
           ++ SS    SH  NR+  KEK    P   +H  S +    SH+   K+SRT  H   +  
Sbjct: 320 EELSS----SHH-NREKAKEK----PRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRG 370

Query: 513 WTTSSGSSKGLGR 525
                GSS+  GR
Sbjct: 371 SERKEGSSRSHGR 383



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 39/174 (22%), Positives = 69/174 (39%), Gaps = 27/174 (15%)

Query: 350 KSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHG 409
           K  +H SS+S S S   S S        TS +++E++ +         ++ K+  SG + 
Sbjct: 251 KHKKHKSSSSSSSSSSSSSSTE------TSESSSESESNNKEKKIQRKKRKKNKCSGHNN 304

Query: 410 --------------RERTQASAEGCKEGRER-----REKDRALGRSSHRRRTGESR-HKT 449
                          E   +S    ++ +E+      E  R   + SH     +SR HK 
Sbjct: 305 SDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKH 364

Query: 450 RGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESR 503
             +K   +    SS SH      ++ +   +PGS + R++ K     P  ++SR
Sbjct: 365 SPEKRGSERKEGSSRSHGREERSRRSRS-RSPGSYKQRETRKRAQRNPGEEQSR 417



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 2/106 (1%)

Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERRE-KDRALGRSSHRRRTGESRHKTRGDKI 454
           S   SK S S    + RT   +   K G ER+E   R+ GR    RR+      +   + 
Sbjct: 344 SREDSKWSHSDSDKKSRTHKHSPE-KRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRE 402

Query: 455 AQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISK 500
            +K + R+    ++ R+D +  G       +    H G +HT +++
Sbjct: 403 TRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHTKVTQ 448


>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
          Length = 221

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 3/88 (3%)

Query: 424 RERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGS 483
           R RR + R+  RS  R R+  SR K+R      +S SRS+   R+ R  K +    +   
Sbjct: 124 RRRRSRSRSRSRSRSRSRSRYSRSKSRS---RTRSRSRSTSKSRSARRSKSKSSSVSRSR 180

Query: 484 SRHRDSHKGVSHTPISKESRTSHKSGRS 511
           SR R   +  S  P+SK    S    +S
Sbjct: 181 SRSRSRSRSRSPPPVSKRESKSRSRSKS 208


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 54/285 (18%), Positives = 102/285 (35%), Gaps = 7/285 (2%)

Query: 263  STELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGG 322
            S E +E      +       + AG+ T TV+ A S     S  G  +  ++   +     
Sbjct: 957  SAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016

Query: 323  NKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTA 382
            +        T++    +T V  AG+   +     S + + S EGS +  ++     + TA
Sbjct: 1017 STTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTA 1076

Query: 383  AEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRT 442
            + AD++      VST  S ++ +   G E T     G K      E   A   S+    T
Sbjct: 1077 STADLETTT---VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133

Query: 443  GESRHKTRGDKIAQ--KSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISK 500
              +   T G ++     + S ++       +       G+  ++   +  +  + +    
Sbjct: 1134 --TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS 1191

Query: 501  ESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTKVVGTP 545
            E+ T+  +G    T S+  S+     +S      A  T     TP
Sbjct: 1192 ETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1236



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 41/180 (22%), Positives = 76/180 (42%), Gaps = 17/180 (9%)

Query: 252 TNVLNASIPKTSTELAEE---PATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQV 308
           T ++ AS   T++    E   P+  G +    + + +   T + AG+ +   +++  G  
Sbjct: 27  TILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTT 86

Query: 309 SAAIAGAATI--DAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREG 366
           +A++AG+ T    AG     +++ GT      +T V+  G+   ++   SS +   S  G
Sbjct: 87  TASMAGSETTVSTAGSETTTVSITGT-----ETTMVSAMGSETTTNSTTSSETTVTSTAG 141

Query: 367 SVSLAIAGVVLTSRTAAEADMDAAAG-------PPVSTRQSKSSLSGQHGRERTQASAEG 419
           S +  ++ V   + TA  AD +  A          V T  S++      G E T  S  G
Sbjct: 142 SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAG 201



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 32/149 (21%), Positives = 55/149 (36%), Gaps = 5/149 (3%)

Query: 271 ATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALA 330
           +T G +    +   +   T +  G  +   +       + +  GA T            A
Sbjct: 527 STEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586

Query: 331 GTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAA 390
            TA     +T V+ A +   ++    S + S S  GS +   +    TS     A  + +
Sbjct: 587 STAGS--ETTTVSTADSENTTASTADSETTSASTTGSETTTAS---TTSSETTTASTEGS 641

Query: 391 AGPPVSTRQSKSSLSGQHGRERTQASAEG 419
               VST  S++++    G ERT  S EG
Sbjct: 642 ETTTVSTTDSETTMVSTTGSERTITSTEG 670



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 45/193 (23%), Positives = 78/193 (40%), Gaps = 12/193 (6%)

Query: 234 TSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVA 293
           TSA+  G E            + ASI  + T +A   +T G +    + A++   T    
Sbjct: 753 TSASTTGSETTTASTTSSETTM-ASIMGSETTMA---STIGSETTKVSTASSKMTTVFTE 808

Query: 294 GALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGA----AG 349
            + +  A+ +A    + + AG+ TI A    G+     T++    +T  +  G+    A 
Sbjct: 809 NSETTIASTTASETTTVSTAGSETIPAS-TAGSETTTTTSTEGSETTTASTEGSETTTAS 867

Query: 350 KSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPP---VSTRQSKSSLSG 406
             S   ++A+   S   + S   +    TS   +E    +  G     VST  S+++ + 
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 407 QHGRERTQASAEG 419
             G E T AS EG
Sbjct: 928 TEGSETTTASTEG 940



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 21/130 (16%)

Query: 262  TSTELAEEP--ATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGA--AT 317
            TSTE +E    +T G +   A+ A +   T + AG+ +  A+ S     +A   G+  +T
Sbjct: 1176 TSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETST 1235

Query: 318  IDAGGNKGNMA--------LAGTASMAPNSTKVA---------VAGAAGKSSEHVSSASM 360
              + G++ N A        +A TAS+ P +T +           A  A  +S  VSS + 
Sbjct: 1236 PSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTF 1295

Query: 361  SLSREGSVSL 370
             L++   VS+
Sbjct: 1296 VLTKATDVSI 1305



 Score = 32.7 bits (73), Expect = 0.97
 Identities = 34/156 (21%), Positives = 61/156 (39%), Gaps = 12/156 (7%)

Query: 272 TGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAG 331
           T   +  AA+   +   T   AG+ ++  + +     + + AG+ T            A 
Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218

Query: 332 TA--------SMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAA 383
           TA        +M   +TKV+ AG+    S   S  + + + +   + A      T+ TA+
Sbjct: 219 TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT-TAS 277

Query: 384 EADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEG 419
               +  A    ST  S+ +++   G E T AS  G
Sbjct: 278 TTGFETTA---ASTTGSEPTMASTMGSETTMASTIG 310



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 43/198 (21%), Positives = 76/198 (38%), Gaps = 21/198 (10%)

Query: 227  VSEVCGATSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAG 286
            VS     T+ A   G  +   F   T V   +   T    A   +  G +    +   + 
Sbjct: 1126 VSTTSSETTTASTTGSEMTTVF---TTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE 1182

Query: 287  AATGTVAGALSVAAANSAPGQVSAAIAGAATIDA--GGNKGNMAL-----AGTASMAPNS 339
              T + AG+ +  A+ +     +A+ AG+ T  A   G++ N A        T S A + 
Sbjct: 1183 TTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1242

Query: 340  TKVA-VAGA----AGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADM------D 388
            T  A + G+    A  +S   ++ S++ S   +VS+  +G    S T +          D
Sbjct: 1243 TNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATD 1302

Query: 389  AAAGPPVSTRQSKSSLSG 406
             +  P  +T  S +  +G
Sbjct: 1303 VSIQPITNTPMSGTRTTG 1320


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 54/285 (18%), Positives = 102/285 (35%), Gaps = 7/285 (2%)

Query: 263  STELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGG 322
            S E +E      +       + AG+ T TV+ A S     S  G  +  ++   +     
Sbjct: 957  SAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016

Query: 323  NKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTA 382
            +        T++    +T V  AG+   +     S + + S EGS +  ++     + TA
Sbjct: 1017 STTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTA 1076

Query: 383  AEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRT 442
            + AD++      VST  S ++ +   G E T     G K      E   A   S+    T
Sbjct: 1077 STADLETTT---VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133

Query: 443  GESRHKTRGDKIAQ--KSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISK 500
              +   T G ++     + S ++       +       G+  ++   +  +  + +    
Sbjct: 1134 --TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS 1191

Query: 501  ESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTKVVGTP 545
            E+ T+  +G    T S+  S+     +S      A  T     TP
Sbjct: 1192 ETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1236



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 41/180 (22%), Positives = 76/180 (42%), Gaps = 17/180 (9%)

Query: 252 TNVLNASIPKTSTELAEE---PATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQV 308
           T ++ AS   T++    E   P+  G +    + + +   T + AG+ +   +++  G  
Sbjct: 27  TILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTT 86

Query: 309 SAAIAGAATI--DAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREG 366
           +A++AG+ T    AG     +++ GT      +T V+  G+   ++   SS +   S  G
Sbjct: 87  TASMAGSETTVSTAGSETTTVSITGT-----ETTMVSAMGSETTTNSTTSSETTVTSTAG 141

Query: 367 SVSLAIAGVVLTSRTAAEADMDAAAG-------PPVSTRQSKSSLSGQHGRERTQASAEG 419
           S +  ++ V   + TA  AD +  A          V T  S++      G E T  S  G
Sbjct: 142 SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAG 201



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 32/149 (21%), Positives = 55/149 (36%), Gaps = 5/149 (3%)

Query: 271 ATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALA 330
           +T G +    +   +   T +  G  +   +       + +  GA T            A
Sbjct: 527 STEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586

Query: 331 GTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAA 390
            TA     +T V+ A +   ++    S + S S  GS +   +    TS     A  + +
Sbjct: 587 STAGS--ETTTVSTADSENTTASTADSETTSASTTGSETTTAS---TTSSETTTASTEGS 641

Query: 391 AGPPVSTRQSKSSLSGQHGRERTQASAEG 419
               VST  S++++    G ERT  S EG
Sbjct: 642 ETTTVSTTDSETTMVSTTGSERTITSTEG 670



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 45/193 (23%), Positives = 78/193 (40%), Gaps = 12/193 (6%)

Query: 234 TSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVA 293
           TSA+  G E            + ASI  + T +A   +T G +    + A++   T    
Sbjct: 753 TSASTTGSETTTASTTSSETTM-ASIMGSETTMA---STIGSETTKVSTASSKMTTVFTE 808

Query: 294 GALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGA----AG 349
            + +  A+ +A    + + AG+ TI A    G+     T++    +T  +  G+    A 
Sbjct: 809 NSETTIASTTASETTTVSTAGSETIPAS-TAGSETTTTTSTEGSETTTASTEGSETTTAS 867

Query: 350 KSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPP---VSTRQSKSSLSG 406
             S   ++A+   S   + S   +    TS   +E    +  G     VST  S+++ + 
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 407 QHGRERTQASAEG 419
             G E T AS EG
Sbjct: 928 TEGSETTTASTEG 940



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 21/130 (16%)

Query: 262  TSTELAEEP--ATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGA--AT 317
            TSTE +E    +T G +   A+ A +   T + AG+ +  A+ S     +A   G+  +T
Sbjct: 1176 TSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETST 1235

Query: 318  IDAGGNKGNMA--------LAGTASMAPNSTKVA---------VAGAAGKSSEHVSSASM 360
              + G++ N A        +A TAS+ P +T +           A  A  +S  VSS + 
Sbjct: 1236 PSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTF 1295

Query: 361  SLSREGSVSL 370
             L++   VS+
Sbjct: 1296 VLTKATDVSI 1305



 Score = 32.7 bits (73), Expect = 0.97
 Identities = 34/156 (21%), Positives = 61/156 (39%), Gaps = 12/156 (7%)

Query: 272 TGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAG 331
           T   +  AA+   +   T   AG+ ++  + +     + + AG+ T            A 
Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218

Query: 332 TA--------SMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAA 383
           TA        +M   +TKV+ AG+    S   S  + + + +   + A      T+ TA+
Sbjct: 219 TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT-TAS 277

Query: 384 EADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEG 419
               +  A    ST  S+ +++   G E T AS  G
Sbjct: 278 TTGFETTA---ASTTGSEPTMASTMGSETTMASTIG 310



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 43/198 (21%), Positives = 76/198 (38%), Gaps = 21/198 (10%)

Query: 227  VSEVCGATSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAG 286
            VS     T+ A   G  +   F   T V   +   T    A   +  G +    +   + 
Sbjct: 1126 VSTTSSETTTASTTGSEMTTVF---TTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE 1182

Query: 287  AATGTVAGALSVAAANSAPGQVSAAIAGAATIDA--GGNKGNMAL-----AGTASMAPNS 339
              T + AG+ +  A+ +     +A+ AG+ T  A   G++ N A        T S A + 
Sbjct: 1183 TTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1242

Query: 340  TKVA-VAGA----AGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADM------D 388
            T  A + G+    A  +S   ++ S++ S   +VS+  +G    S T +          D
Sbjct: 1243 TNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATD 1302

Query: 389  AAAGPPVSTRQSKSSLSG 406
             +  P  +T  S +  +G
Sbjct: 1303 VSIQPITNTPMSGTRTTG 1320


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.126    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,776,148
Number of Sequences: 37866
Number of extensions: 888142
Number of successful extensions: 6213
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 148
Number of HSP's successfully gapped in prelim test: 333
Number of HSP's that attempted gapping in prelim test: 4164
Number of HSP's gapped (non-prelim): 1617
length of query: 594
length of database: 18,247,518
effective HSP length: 108
effective length of query: 486
effective length of database: 14,157,990
effective search space: 6880783140
effective search space used: 6880783140
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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