BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|23957696 hypothetical protein LOC149647 [Homo sapiens] (594 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|23957696 hypothetical protein LOC149647 [Homo sapiens] 1163 0.0 gi|222418633 family with sequence similarity 71, member B [Homo ... 503 e-142 gi|23503301 hypothetical protein LOC196472 [Homo sapiens] 261 1e-69 gi|89363024 hypothetical protein LOC161142 [Homo sapiens] 107 4e-23 gi|76253859 hypothetical protein LOC112703 [Homo sapiens] 106 5e-23 gi|223972704 hypothetical protein LOC284418 [Homo sapiens] 92 1e-18 gi|14211935 testes development-related NYD-SP18 [Homo sapiens] 85 2e-16 gi|193083150 hypothetical protein LOC346653 isoform b [Homo sapi... 73 8e-13 gi|149192824 hypothetical protein LOC346653 isoform a [Homo sapi... 65 2e-10 gi|161016767 mucin 21 [Homo sapiens] 55 1e-07 gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 53 7e-07 gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 53 7e-07 gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens] 52 2e-06 gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 50 4e-06 gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 49 1e-05 gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 48 2e-05 gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 48 2e-05 gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens] 47 4e-05 gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens] 47 4e-05 gi|24497554 homeobox A13 [Homo sapiens] 47 6e-05 gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 46 8e-05 gi|57864582 hornerin [Homo sapiens] 46 1e-04 gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 45 1e-04 gi|60097902 filaggrin [Homo sapiens] 45 2e-04 gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 43 7e-04 gi|33356174 pinin, desmosome associated protein [Homo sapiens] 43 7e-04 gi|40068059 CBF1 interacting corepressor [Homo sapiens] 42 0.002 gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens] 42 0.002 gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002 gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002 >gi|23957696 hypothetical protein LOC149647 [Homo sapiens] Length = 594 Score = 1163 bits (3009), Expect = 0.0 Identities = 594/594 (100%), Positives = 594/594 (100%) Query: 1 MNADFLLPYYTAQSGSSMSMFDTTMGKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVI 60 MNADFLLPYYTAQSGSSMSMFDTTMGKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVI Sbjct: 1 MNADFLLPYYTAQSGSSMSMFDTTMGKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVI 60 Query: 61 DVHNRVRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTR 120 DVHNRVRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTR Sbjct: 61 DVHNRVRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTR 120 Query: 121 LLPLRFVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPMES 180 LLPLRFVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPMES Sbjct: 121 LLPLRFVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPMES 180 Query: 181 NSSTCGIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAYAG 240 NSSTCGIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAYAG Sbjct: 181 NSSTCGIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAYAG 240 Query: 241 GEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAA 300 GEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAA Sbjct: 241 GEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAA 300 Query: 301 ANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASM 360 ANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASM Sbjct: 301 ANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASM 360 Query: 361 SLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGC 420 SLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGC Sbjct: 361 SLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGC 420 Query: 421 KEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGN 480 KEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGN Sbjct: 421 KEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGN 480 Query: 481 PGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTK 540 PGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTK Sbjct: 481 PGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTK 540 Query: 541 VVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGLEMVGSMTPDIMETVTFEAH 594 VVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGLEMVGSMTPDIMETVTFEAH Sbjct: 541 VVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGLEMVGSMTPDIMETVTFEAH 594 >gi|222418633 family with sequence similarity 71, member B [Homo sapiens] Length = 605 Score = 503 bits (1295), Expect = e-142 Identities = 300/612 (49%), Positives = 396/612 (64%), Gaps = 31/612 (5%) Query: 1 MNADFLLPYYTAQSGSSMSMFDTTMGKLQRQLY-KGEYDIFKYAPIFESDFIQITKRGEV 59 M+ + LPYYTA S SSMS F T+MG LQRQLY +GEY+IFKYAP+FES+FIQI K+GEV Sbjct: 1 MSNESCLPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEV 60 Query: 60 IDVHNRVRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELT 119 IDVHNRVRMVT+GI TSPILPLPDVM+LA+P CE++ G+ K + R+ K LELT Sbjct: 61 IDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELT 120 Query: 120 RLLPLRFVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPME 179 RLLPL+FV+IS+ DHEKQQLRLK ATGR+ YLQLCP+ DTR+DLF YWEKL+YLLRPP+E Sbjct: 121 RLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVE 180 Query: 180 SNSSTCGIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAYA 239 S ST + + D ED +SL A L +GDQ + L+ +V ATS+AYA Sbjct: 181 SYCSTPTLLSGDAP-----PEDNKSLVAAELHREGDQSET---GLYKPCDVSAATSSAYA 232 Query: 240 GGEGLQNDFNKPTNVLNASIPKTSTELAEE----PATGGIKEAAAAG------AAAGAAT 289 GGEG+Q+ + +A+ P TST A E GG+ A A A AGAA Sbjct: 233 GGEGIQHASH---GTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAM 289 Query: 290 GTVAGALSVAAANSA-PGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAA 348 GA+S+A SA PGQV+ A+AGAA + G N+ + ++AG A+++ +A+ GAA Sbjct: 290 SPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAA 349 Query: 349 GKSSEHVSSA---SMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLS 405 S E S++ + SLS++ S+S A AG + TS+ AAE A GP +ST QS+ +S Sbjct: 350 STSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMS 409 Query: 406 GQHGRER-TQASAEGCKEGRERRE-KDRALGR-SSHRRRTGESRHKTRGDKIAQKSSSRS 462 + G ++ +Q SAE E +ERRE KDR R SSH R+ GES + GDK + SS RS Sbjct: 410 ERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRS 469 Query: 463 SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGS-SK 521 + H+ RDDKKEKG N RH S K +H+ KESRT+ + G++ +S+G+ K Sbjct: 470 ASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQK 529 Query: 522 GLGRVSSFLRNVRANLTTKVVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGLEMV-GS 580 ++SSFLR++RA +K T H R+VD++AKM E+ A E A+GGQ LEM+ G+ Sbjct: 530 KASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELEMISGT 589 Query: 581 MTPDIMETVTFE 592 MT + E + FE Sbjct: 590 MTSEKTEMIVFE 601 >gi|23503301 hypothetical protein LOC196472 [Homo sapiens] Length = 241 Score = 261 bits (668), Expect = 1e-69 Identities = 136/233 (58%), Positives = 172/233 (73%), Gaps = 1/233 (0%) Query: 6 LLPYYTAQSGSSMSMFDTTMGKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNR 65 +LPYYTAQS +M MF+T+MGKLQRQLYKGEY IF+YAP+FESDFIQI+KRGEVIDVHNR Sbjct: 6 MLPYYTAQSSPAMGMFNTSMGKLQRQLYKGEYTIFRYAPMFESDFIQISKRGEVIDVHNR 65 Query: 66 VRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLR 125 RMVTMGI RTSP L LPDVMLLARPA C+ A G AT++++ A+ LELTRLLPL Sbjct: 66 ARMVTMGIVRTSPCLTLPDVMLLARPAAVCDN-ARCGPATQKRESPPAEILELTRLLPLM 124 Query: 126 FVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPMESNSSTC 185 FV+I++ + K+QL LK ATGRS YLQLCP D +DLF +WE L+Y+LRPP+E+ S T Sbjct: 125 FVKITIHNSVKKQLHLKLATGRSFYLQLCPPSDASEDLFVHWENLVYILRPPVEAYSDTR 184 Query: 186 GIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAY 238 I A + + V +E +RS ++ +++Q I LHM +E+ G+T Y Sbjct: 185 AILAGNTLDSSVLEEVQRSPVGYAMKFCEEKEQFRISRLHMNAEMFGSTYCDY 237 >gi|89363024 hypothetical protein LOC161142 [Homo sapiens] Length = 422 Score = 107 bits (266), Expect = 4e-23 Identities = 63/147 (42%), Positives = 84/147 (57%), Gaps = 1/147 (0%) Query: 28 LQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNRVRMVTMGIARTSPILPLPDVML 87 LQ L GEY F P+ ES+FIQ+ +RGE I +HNR VT+GI +S +P+VML Sbjct: 29 LQNMLDGGEYAPFVSPPMLESNFIQVNRRGESIYLHNRANWVTVGICFSSSTHKIPNVML 88 Query: 88 LARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEKQQLRLKFATGR 147 LA G ++ A+ L LTR LPL+FV +SV D E L++K +GR Sbjct: 89 LAHLTPGAQKDT-ETLFKSLLTSPPAEKLVLTRFLPLQFVTLSVHDAENMSLKVKLVSGR 147 Query: 148 SCYLQLCPALDTRDDLFAYWEKLIYLL 174 + YLQLC + +D LF+ W LI LL Sbjct: 148 AYYLQLCTSAYKQDTLFSQWVALISLL 174 >gi|76253859 hypothetical protein LOC112703 [Homo sapiens] Length = 231 Score = 106 bits (265), Expect = 5e-23 Identities = 64/149 (42%), Positives = 86/149 (57%), Gaps = 24/149 (16%) Query: 27 KLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNRVRMVTMGIARTSPILPLPDVM 86 +LQR L GE+D F+ PIFES+F+Q+T+ GEV + VTMG+A +SP L LPD++ Sbjct: 95 RLQRYLQSGEFDQFRDFPIFESNFVQVTRLGEVANE------VTMGVAASSPALELPDLL 148 Query: 87 LLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEKQQLRLKFATG 146 LLA PA K +L+L L PL+FV++ V D + QL +K T Sbjct: 149 LLAGPA------------------KENGHLQLFGLFPLKFVQLFVHDKSRCQLEVKLNTS 190 Query: 147 RSCYLQLCPALDTRDDLFAYWEKLIYLLR 175 R+ YLQL L TRD F W +L+Y LR Sbjct: 191 RTFYLQLRAPLKTRDREFGQWVRLLYRLR 219 >gi|223972704 hypothetical protein LOC284418 [Homo sapiens] Length = 922 Score = 92.0 bits (227), Expect = 1e-18 Identities = 56/157 (35%), Positives = 87/157 (55%), Gaps = 24/157 (15%) Query: 25 MGKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNRVRMVTMGIARTSPILPLPD 84 +G+LQ+ L KGEY + P+FES+F+Q+T +G + V++R + MG+A + P L LPD Sbjct: 23 LGELQKTLQKGEYLPLRPLPMFESNFVQVTHQGGPVFVNHRTNRLAMGVAASLPGLVLPD 82 Query: 85 VMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEKQQLRLKFA 144 ++L+ +PA + + L LTR++PL V + V D +L+L+ Sbjct: 83 ILLIGQPA----------------EDRDCSGLVLTRMIPLDLVHLCVHDLSAWRLKLRLV 126 Query: 145 TGRSCYLQLCPALDTRDD----LFAYWEKLIYLLRPP 177 +GR YL ALD D+ LF W +LI LL+ P Sbjct: 127 SGRQYYL----ALDAPDNEVGFLFHCWVRLINLLQEP 159 >gi|14211935 testes development-related NYD-SP18 [Homo sapiens] Length = 344 Score = 84.7 bits (208), Expect = 2e-16 Identities = 58/209 (27%), Positives = 104/209 (49%), Gaps = 22/209 (10%) Query: 26 GKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNRVRMVTMGIARTSPILPLPDV 85 G L R ++ E+++F + +FES+FIQ+ + DV+ + +G+ + P LPLP++ Sbjct: 57 GLLCRVVHSPEFNLFLDSVVFESNFIQVKRGRNWRDVYKASNTMALGVTSSVPCLPLPNI 116 Query: 86 MLLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEKQQLRLKFAT 145 +L+A + + G Q R A N+ L R+LPLRFV + V DH ++ L+L+ T Sbjct: 117 LLMA----SVKWHQGQNQTWNRP--SIAPNIFLKRILPLRFVELQVCDHYQRILQLRTVT 170 Query: 146 GRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPMESNS-------------STCGIPAED- 191 + YL+L P D + +F +W +L+ +L+ + + C P+ D Sbjct: 171 EKIYYLKLHP--DHPETVFHFWIRLVQILQKGLSITTKDPRILVTHCLVPKNCSSPSGDS 228 Query: 192 MMWMPVFQEDRRSLGAVNLQGKGDQDQVS 220 + Q + S + L KG+ + +S Sbjct: 229 KLVQKKLQASQPSESLIQLMTKGESEALS 257 >gi|193083150 hypothetical protein LOC346653 isoform b [Homo sapiens] Length = 300 Score = 72.8 bits (177), Expect = 8e-13 Identities = 46/150 (30%), Positives = 81/150 (54%), Gaps = 8/150 (5%) Query: 26 GKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNRVRMVTMGIARTSPILPLPDV 85 G L + ++ E+++F + +FES+FIQ+TK G DV V +G+ + P LPLP+V Sbjct: 25 GLLCQLIHSPEFNLFSNSVVFESNFIQVTKPGNWRDVCEGSATVILGVTSSVPSLPLPNV 84 Query: 86 MLLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEKQQLRLKFAT 145 +L+A G T A + L+RLLPL++V + + D ++ LR++ T Sbjct: 85 LLMANVTW------PQGPFTTWSTPGDAPVINLSRLLPLKYVELRIYDRLQRILRVRTVT 138 Query: 146 GRSCYLQLCPALDTRDDLFAYWEKLIYLLR 175 + YL+L + +F +W +L+ +L+ Sbjct: 139 EKIYYLKLHE--KHPEIVFQFWVRLVKILQ 166 >gi|149192824 hypothetical protein LOC346653 isoform a [Homo sapiens] Length = 309 Score = 65.1 bits (157), Expect = 2e-10 Identities = 46/159 (28%), Positives = 81/159 (50%), Gaps = 17/159 (10%) Query: 26 GKLQRQLYKGEYDIFKYAPIFESDFIQ---------ITKRGEVIDVHNRVRMVTMGIART 76 G L + ++ E+++F + +FES+FIQ +TK G DV V +G+ + Sbjct: 25 GLLCQLIHSPEFNLFSNSVVFESNFIQTHVPEADFQVTKPGNWRDVCEGSATVILGVTSS 84 Query: 77 SPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEK 136 P LPLP+V+L+A G T A + L+RLLPL++V + + D + Sbjct: 85 VPSLPLPNVLLMANVTW------PQGPFTTWSTPGDAPVINLSRLLPLKYVELRIYDRLQ 138 Query: 137 QQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLR 175 + LR++ T + YL+L + +F +W +L+ +L+ Sbjct: 139 RILRVRTVTEKIYYLKLHE--KHPEIVFQFWVRLVKILQ 175 >gi|161016767 mucin 21 [Homo sapiens] Length = 566 Score = 55.5 bits (132), Expect = 1e-07 Identities = 68/322 (21%), Positives = 123/322 (38%), Gaps = 21/322 (6%) Query: 263 STELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGG 322 S+ + E +T E++ + A AT + + +S A+ + + S +GA+T Sbjct: 155 SSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSE 214 Query: 323 NKGNMALAGTASMAPNSTKVAVAGAA--GKSSEHVSSASMSLSREGSVSLAIAGVVLTSR 380 ++ AGTA+ + +ST + A A +SS S A + + E S + + AG + Sbjct: 215 SRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAG----TA 270 Query: 381 TAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRR 440 T +E+ ++ V+ +S + SG + +++S + Sbjct: 271 TNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTA 330 Query: 441 RTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISK 500 ES + G A S S ++ S G +S + G S S+ Sbjct: 331 TNSESSTTSSGASTATNSESSTTSS-----------GASTATNSGSSTTSSGTSTATNSE 379 Query: 501 ESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTKVVGTPHGRDVDVMAKMAERS 560 S S SG S TTS S+ G +S N ++ + T + + A + Sbjct: 380 SSTVS--SGASTATTSESSTTSSG--ASTATNSESSTVSSGASTATNSESSTTSSGANTA 435 Query: 561 TNVAIAETAEGGQGLEMVGSMT 582 TN + T+ G + G T Sbjct: 436 TNSGSSVTSAGSGTAALTGMHT 457 Score = 45.4 bits (106), Expect = 1e-04 Identities = 63/307 (20%), Positives = 115/307 (37%), Gaps = 25/307 (8%) Query: 278 AAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAP 337 ++ A + TV+ +S+A + + S +GA+T + + A TA+ + Sbjct: 84 SSGISTATNSEFSTVSSGISIATNSES----STTSSGASTATNSESSTPSSGASTATNSD 139 Query: 338 NSTKVAVAGAAGKSSEHVSS--ASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPV 395 +ST + A A S +S AS + + E S + + A S ++ + + A Sbjct: 140 SSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSE 199 Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455 S+ S + + + RT ++ G E +++ ES + G A Sbjct: 200 SSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATN----SESSTPSSGAGTA 255 Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTT 515 S S ++ S G G +S G+S S+ S S SG + T Sbjct: 256 TNSESSTTSS-----------GAGTATNSESSTVSSGISTVTNSESSTPS--SGANTATN 302 Query: 516 SSGSSKGLGRVSSFLRNVRANLTTKVVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGL 575 S S+ G ++ N ++ T+ T + + A +TN + T+ G Sbjct: 303 SESSTTSSG--ANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTA 360 Query: 576 EMVGSMT 582 GS T Sbjct: 361 TNSGSST 367 Score = 34.7 bits (78), Expect = 0.25 Identities = 37/171 (21%), Positives = 70/171 (40%), Gaps = 19/171 (11%) Query: 232 GATSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGT 291 GA++A +G + + TN S+ ++ +T E++ + A AT + Sbjct: 356 GASTATNSGSSTTSSGTSTATN-------SESSTVSSGASTATTSESSTTSSGASTATNS 408 Query: 292 VAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKS 351 + +S A+ + + S +GA T G+ A +GTA++ T Sbjct: 409 ESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHT----------- 457 Query: 352 SEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKS 402 + H +S ++S ++ G SL + L + + A + AG R S S Sbjct: 458 TSHSASTAVSEAKPGG-SLVPWEIFLITLVSVVAAVGLFAGLFFCVRNSLS 507 >gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] Length = 2426 Score = 53.1 bits (126), Expect = 7e-07 Identities = 41/136 (30%), Positives = 62/136 (45%), Gaps = 16/136 (11%) Query: 399 QSKSSLSGQH-GRERTQASAEGCKE----GRERREKDRALGRSSHRRRTGESRHKTRGDK 453 +SK S S +H R+RT S ++ + R + R+ RS RRR+ SR K+RG + Sbjct: 1825 RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRR 1884 Query: 454 IAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLW 513 K + S HR+ ++K K S RD+ K + SRT + RS Sbjct: 1885 SVSKEKRKRSPKHRSKSRERKRK------RSSSRDNRK-----TVRARSRTPSRRSRSHT 1933 Query: 514 TTSSGSSKGLGRVSSF 529 + S+ +GR SF Sbjct: 1934 PSRRRRSRSVGRRRSF 1949 Score = 36.6 bits (83), Expect = 0.067 Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 22/165 (13%) Query: 362 LSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRE------RTQA 415 + R S+ I G +L S + +AA P VS+ ++S S ++ + + Sbjct: 1742 MERLTSLRAGIEGPLLASDVGRDR---SAASPVVSSMPERASESSSEEKDDYEIFVKVKD 1798 Query: 416 SAEGCKEGRER----REKDRALGRSSHRRRTGESRHKTR-----GDKIAQKSSSRSSFSH 466 + E K+ + R +EK R S +R+ S HK+R A+K SS+S SH Sbjct: 1799 THEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSK-SH 1857 Query: 467 RANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511 R ++ + + SSR R +G +SKE R RS Sbjct: 1858 R-SQTRSRSRSRRRRRSSRSRSKSRG--RRSVSKEKRKRSPKHRS 1899 Score = 33.5 bits (75), Expect = 0.57 Identities = 33/124 (26%), Positives = 56/124 (45%), Gaps = 10/124 (8%) Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSS----HRRRTGESRHKTRG 451 S + +SS S H R +T++ + + R R + ++ GR S R+R+ + R K+R Sbjct: 1845 SRARKRSSKSKSH-RSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRE 1903 Query: 452 DKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKG----VSHTPISKESRTSHK 507 K + SS + + RA + + S R R G S +P S+ SRT + Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISP-SRRSRTPSR 1962 Query: 508 SGRS 511 R+ Sbjct: 1963 RSRT 1966 >gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] Length = 2303 Score = 53.1 bits (126), Expect = 7e-07 Identities = 41/136 (30%), Positives = 62/136 (45%), Gaps = 16/136 (11%) Query: 399 QSKSSLSGQH-GRERTQASAEGCKE----GRERREKDRALGRSSHRRRTGESRHKTRGDK 453 +SK S S +H R+RT S ++ + R + R+ RS RRR+ SR K+RG + Sbjct: 1825 RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRR 1884 Query: 454 IAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLW 513 K + S HR+ ++K K S RD+ K + SRT + RS Sbjct: 1885 SVSKEKRKRSPKHRSKSRERKRK------RSSSRDNRK-----TVRARSRTPSRRSRSHT 1933 Query: 514 TTSSGSSKGLGRVSSF 529 + S+ +GR SF Sbjct: 1934 PSRRRRSRSVGRRRSF 1949 Score = 36.6 bits (83), Expect = 0.067 Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 22/165 (13%) Query: 362 LSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRE------RTQA 415 + R S+ I G +L S + +AA P VS+ ++S S ++ + + Sbjct: 1742 MERLTSLRAGIEGPLLASDVGRDR---SAASPVVSSMPERASESSSEEKDDYEIFVKVKD 1798 Query: 416 SAEGCKEGRER----REKDRALGRSSHRRRTGESRHKTR-----GDKIAQKSSSRSSFSH 466 + E K+ + R +EK R S +R+ S HK+R A+K SS+S SH Sbjct: 1799 THEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSK-SH 1857 Query: 467 RANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511 R ++ + + SSR R +G +SKE R RS Sbjct: 1858 R-SQTRSRSRSRRRRRSSRSRSKSRG--RRSVSKEKRKRSPKHRS 1899 Score = 33.5 bits (75), Expect = 0.57 Identities = 33/124 (26%), Positives = 56/124 (45%), Gaps = 10/124 (8%) Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSS----HRRRTGESRHKTRG 451 S + +SS S H R +T++ + + R R + ++ GR S R+R+ + R K+R Sbjct: 1845 SRARKRSSKSKSH-RSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRE 1903 Query: 452 DKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKG----VSHTPISKESRTSHK 507 K + SS + + RA + + S R R G S +P S+ SRT + Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISP-SRRSRTPSR 1962 Query: 508 SGRS 511 R+ Sbjct: 1963 RSRT 1966 >gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens] Length = 352 Score = 51.6 bits (122), Expect = 2e-06 Identities = 63/240 (26%), Positives = 97/240 (40%), Gaps = 28/240 (11%) Query: 275 IKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTAS 334 ++ A AG GA G + A A + +A GAA+ D G Sbjct: 1 MERAGPAGEEGGAREGRLLPRAPGAWVLRACAERAALEVGAASADTG------------- 47 Query: 335 MAPNSTKVAVAGAAGKSSEHVSSASMSLSREGS--VSLAIAGVVLTSRTAAEA-DMDAAA 391 V GA G + ++SA +R+G+ V +G L SR A+ A A+ Sbjct: 48 -------VRGCGARGPAPL-LASAGGGRARDGTWGVRTKGSGAALPSRPASRAAPRPEAS 99 Query: 392 GPPVSTRQSKSSLSG-QHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTR 450 PP+ +++ LSG Q GR R + G + + R + R+ GR S +R+ +SR T Sbjct: 100 SPPLPLEKARGGLSGPQGGRARGAMAHVGSR--KRSRSRSRSRGRGSEKRKK-KSRKDTS 156 Query: 451 GDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR 510 + A S R + + + K+K SS S S + S S +S GR Sbjct: 157 RNCSASTSQGRKASTAPGAEERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGR 216 >gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] Length = 819 Score = 50.4 bits (119), Expect = 4e-06 Identities = 80/347 (23%), Positives = 123/347 (35%), Gaps = 41/347 (11%) Query: 251 PTNVLNASIPKTSTELAEEPATGGIKEAAAA--------------GAAAGAATGTVAGAL 296 P L A++ +T ELA E A + AAA AAAG + G Sbjct: 18 PGAPLGAALARTPVELAAESAAPALSAAAAGVKILGSGDKKLRRQKAAAGGKKARLRGQK 77 Query: 297 SVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAG--AAGKSSE- 353 A A A + GG + A AGT S+ K G AA S+ Sbjct: 78 GAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRGRKPRRRGQKAAATGSKK 137 Query: 354 -----HVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQH 408 S+A+ S +R A A + S+ + AAAG S SG+ Sbjct: 138 PRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAG--------AKSRSGKK 189 Query: 409 GRER-TQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHR 467 R R ++ + K+GR+R K R G++ R G + R A + SR + Sbjct: 190 PRRRGAKSRGDEDKKGRQREAKSR-FGKT----RGGRRKKHRRPKPAAGGAKSRRGGGKK 244 Query: 468 ANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVS 527 + ++ + G SR S G K+ R ++ G++ + + Sbjct: 245 PQKQRRRGQKAATGGKSRVGKSRGGG-----DKKLRRQGQNAALAGAKRRGAATAGEKPA 299 Query: 528 SFLRNVRANLTTKVVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQG 574 + R R + GR + +++T A A T GG G Sbjct: 300 AKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGG 346 Score = 35.8 bits (81), Expect = 0.11 Identities = 61/265 (23%), Positives = 92/265 (34%), Gaps = 22/265 (8%) Query: 276 KEAAAAGAAAGAATG------TVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMAL 329 ++A AAGA + VAGA S + + + A AGA + GGNK + Sbjct: 511 EKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRGG 570 Query: 330 AGTASMAPNSTKVAVAGAAGKSSE---HVSSASMSLSREGS-------VSLAIAGVVLTS 379 G T A G + ++A ++ SR G A G Sbjct: 571 GGNKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKSRK 630 Query: 380 RTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHR 439 + DAAA + S SG + +A G + A R R Sbjct: 631 KPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPR 690 Query: 440 RRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPIS 499 RR R K+RGD Q ++ + R + + K G G ++ R S S Sbjct: 691 RR----RAKSRGDG-GQNAAVGINPWQRRGKKPRLGKSRGG-GGAKSRGSGGAKSRGSGG 744 Query: 500 KESRTSHKSGRSLWTTSSGSSKGLG 524 +SR+ K+ S G+ + G Sbjct: 745 AKSRSGKKAAASKSHGGGGAKRRRG 769 Score = 30.8 bits (68), Expect = 3.7 Identities = 61/280 (21%), Positives = 96/280 (34%), Gaps = 48/280 (17%) Query: 320 AGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTS 379 AGG K + A G + + L R+G + A+AG Sbjct: 232 AGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQ-NAALAGA--KR 288 Query: 380 RTAAEA-DMDAAAGPPVSTRQSKSSLSGQH-------------GRERTQASAEGCKEGR- 424 R AA A + AA G + SL GQ+ G++ T+A+A G K G Sbjct: 289 RGAATAGEKPAAKG---RGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGG 345 Query: 425 ----------ERREKDRALGRSSHRRRTGESRHKTR--GDKIAQKSSSRSSFSHRANRDD 472 + R+K R G+ R++ + K+R GDK + + R D Sbjct: 346 GQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRG-------DG 398 Query: 473 KKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRN 532 +K+ NP R + K + P S+ + G + G S+ G R Sbjct: 399 RKKPRWQNP----RRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRG 454 Query: 533 VRANLTTKVVGTPHGRDVDVMAKMAERSTNVAIAETAEGG 572 +A G D K + + A ++ GG Sbjct: 455 QKARQKAAEAGAESRGD----KKQGRQKASAAGTKSRGGG 490 >gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] Length = 330 Score = 48.9 bits (115), Expect = 1e-05 Identities = 42/153 (27%), Positives = 67/153 (43%), Gaps = 9/153 (5%) Query: 379 SRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSH 438 S+ +A + + S R+S+S H R +++S+ R R + S Sbjct: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSR 240 Query: 439 RRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPI 498 R + R ++RG K +SSSR SHR + +K + + SS R+ + S + Sbjct: 241 SRSSSRERSRSRGSK--SRSSSR---SHRGSSSPRK-RSYSSSSSSPERNRKRSRSRSSS 294 Query: 499 S---KESRTSHKSGRSLWTTSSGSSKGLGRVSS 528 S K+ RT +S +SSGSS R SS Sbjct: 295 SGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327 Score = 38.5 bits (88), Expect = 0.018 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 7/115 (6%) Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRER-REKDRALG---RSSHRRRTGESRHKTRG 451 S+R S S S R R+++S+ R RE+ R+ G RSS R G S + R Sbjct: 214 SSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRS 273 Query: 452 DKIAQKSSSRS---SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESR 503 + S R+ S S ++ D+K++ + R S G SH+ S+ Sbjct: 274 YSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328 Score = 37.0 bits (84), Expect = 0.051 Identities = 32/127 (25%), Positives = 52/127 (40%), Gaps = 8/127 (6%) Query: 350 KSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHG 409 +SS SS S S SR S S + + SR+++ + S S+S Sbjct: 212 RSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSK--SRSSSRSHRGSSSP 269 Query: 410 RERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRAN 469 R+R+ +S+ E +R + R+ ++R SR R + S S SH + Sbjct: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPER------RHRSSSGSSHSGS 323 Query: 470 RDDKKEK 476 R K+K Sbjct: 324 RSSSKKK 330 >gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] Length = 1512 Score = 48.1 bits (113), Expect = 2e-05 Identities = 70/246 (28%), Positives = 94/246 (38%), Gaps = 38/246 (15%) Query: 287 AATGTVAGALSVAAANSA------PGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNST 340 AA GT A A + AAA+S+ P +V G AGG + A Sbjct: 62 AAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRR--AGGRQKRRRGPRAGQEAEKRR 119 Query: 341 KVAVA-----GAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPV 395 ++ G G SS + + E S + G++L +AA A AAG Sbjct: 120 VFSLPQPQQDGGGGASSG--GGVTPLVEYEDVSSQSEQGLLLGGASAATAA--TAAGGTG 175 Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455 + S +S SG TQ EG E R RR++ + GRS R R R RG A Sbjct: 176 GSGGSPASSSG------TQRRGEG-SERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEA 228 Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPG--------------SSRHRDSHKGVSHTPISKE 501 KS SR S S + K + G S + RDS S T SKE Sbjct: 229 SKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKE 288 Query: 502 SRTSHK 507 +++K Sbjct: 289 PPSAYK 294 Score = 45.1 bits (105), Expect = 2e-04 Identities = 64/240 (26%), Positives = 92/240 (38%), Gaps = 20/240 (8%) Query: 296 LSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHV 355 L +AA +A +AA A ++ G LA A K AG+ +E Sbjct: 59 LFLAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKR 118 Query: 356 SSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQA 415 S+ ++ A +G +T E VS++ + L G T A Sbjct: 119 RVFSLPQPQQDGGGGASSGGGVTPLVEYE---------DVSSQSEQGLLLGG-ASAATAA 168 Query: 416 SAEGCKEGRERREKDRALGRSSHRRRTGE-SRHKTRGDKIAQKSSSRSSFSHRANRDDKK 474 +A G G + SS +R GE S + R D+ + SS RS HR +R Sbjct: 169 TAAGGTGG-----SGGSPASSSGTQRRGEGSERRPRRDR--RSSSGRSKERHREHRRRDG 221 Query: 475 EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR--SLWTTSSGSSKGLGRVSSFLRN 532 ++G SR R SH G ++K +S GR S TSS SS R S R+ Sbjct: 222 QRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRS 281 >gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] Length = 1452 Score = 48.1 bits (113), Expect = 2e-05 Identities = 70/246 (28%), Positives = 94/246 (38%), Gaps = 38/246 (15%) Query: 287 AATGTVAGALSVAAANSA------PGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNST 340 AA GT A A + AAA+S+ P +V G AGG + A Sbjct: 62 AAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRR--AGGRQKRRRGPRAGQEAEKRR 119 Query: 341 KVAVA-----GAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPV 395 ++ G G SS + + E S + G++L +AA A AAG Sbjct: 120 VFSLPQPQQDGGGGASSG--GGVTPLVEYEDVSSQSEQGLLLGGASAATAA--TAAGGTG 175 Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455 + S +S SG TQ EG E R RR++ + GRS R R R RG A Sbjct: 176 GSGGSPASSSG------TQRRGEG-SERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEA 228 Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPG--------------SSRHRDSHKGVSHTPISKE 501 KS SR S S + K + G S + RDS S T SKE Sbjct: 229 SKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKE 288 Query: 502 SRTSHK 507 +++K Sbjct: 289 PPSAYK 294 Score = 45.1 bits (105), Expect = 2e-04 Identities = 64/240 (26%), Positives = 92/240 (38%), Gaps = 20/240 (8%) Query: 296 LSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHV 355 L +AA +A +AA A ++ G LA A K AG+ +E Sbjct: 59 LFLAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKR 118 Query: 356 SSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQA 415 S+ ++ A +G +T E VS++ + L G T A Sbjct: 119 RVFSLPQPQQDGGGGASSGGGVTPLVEYE---------DVSSQSEQGLLLGG-ASAATAA 168 Query: 416 SAEGCKEGRERREKDRALGRSSHRRRTGE-SRHKTRGDKIAQKSSSRSSFSHRANRDDKK 474 +A G G + SS +R GE S + R D+ + SS RS HR +R Sbjct: 169 TAAGGTGG-----SGGSPASSSGTQRRGEGSERRPRRDR--RSSSGRSKERHREHRRRDG 221 Query: 475 EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR--SLWTTSSGSSKGLGRVSSFLRN 532 ++G SR R SH G ++K +S GR S TSS SS R S R+ Sbjct: 222 QRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRS 281 >gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens] Length = 338 Score = 47.4 bits (111), Expect = 4e-05 Identities = 62/240 (25%), Positives = 98/240 (40%), Gaps = 39/240 (16%) Query: 275 IKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTAS 334 ++ A AG GA G + A A + +A GAA+ D G Sbjct: 1 MERAGPAGEEGGAREGRLLPRAPGAWVLRACAERAALEVGAASADTG------------- 47 Query: 335 MAPNSTKVAVAGAAGKSSEHVSSASMSLSREGS--VSLAIAGVVLTSRTAAEA-DMDAAA 391 V GA G + ++SA +R+G+ V +G L SR A+ A A+ Sbjct: 48 -------VRGCGARGPAPL-LASAGGGRARDGTWGVRTKGSGAALPSRPASRAAPRPEAS 99 Query: 392 GPPVSTRQSKSSLSG-QHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTR 450 PP+ +++ LSG Q GR R + G + + R + R+ GR S +R+ Sbjct: 100 SPPLPLEKARGGLSGPQGGRARGAMAHVGSR--KRSRSRSRSRGRGSEKRK--------- 148 Query: 451 GDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR 510 K ++K +SR+ S +++ K+K SS S S + S S +S GR Sbjct: 149 --KKSRKDTSRNC-SASTSQERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGR 205 Score = 31.6 bits (70), Expect = 2.2 Identities = 30/154 (19%), Positives = 64/154 (41%), Gaps = 2/154 (1%) Query: 282 GAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTK 341 G+ A + + A A+S P + A G + G +G MA G+ + + ++ Sbjct: 79 GSGAALPSRPASRAAPRPEASSPPLPLEKARGGLSGPQGGRARGAMAHVGSRKRSRSRSR 138 Query: 342 VAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSK 401 G+ + + S + S S S + RT + + +++ S+ S Sbjct: 139 SRGRGSEKRKKKSRKDTSRNCS--ASTSQERSKQKARRRTRSSSSSSSSSSSSSSSSSSS 196 Query: 402 SSLSGQHGRERTQASAEGCKEGRERREKDRALGR 435 SS S GR++ + ++ +++R+K + G+ Sbjct: 197 SSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGK 230 >gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens] Length = 341 Score = 47.4 bits (111), Expect = 4e-05 Identities = 62/240 (25%), Positives = 98/240 (40%), Gaps = 39/240 (16%) Query: 275 IKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTAS 334 ++ A AG GA G + A A + +A GAA+ D G Sbjct: 1 MERAGPAGEEGGAREGRLLPRAPGAWVLRACAERAALEVGAASADTG------------- 47 Query: 335 MAPNSTKVAVAGAAGKSSEHVSSASMSLSREGS--VSLAIAGVVLTSRTAAEA-DMDAAA 391 V GA G + ++SA +R+G+ V +G L SR A+ A A+ Sbjct: 48 -------VRGCGARGPAPL-LASAGGGRARDGTWGVRTKGSGAALPSRPASRAAPRPEAS 99 Query: 392 GPPVSTRQSKSSLSG-QHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTR 450 PP+ +++ LSG Q GR R + G + + R + R+ GR S +R+ Sbjct: 100 SPPLPLEKARGGLSGPQGGRARGAMAHVGSR--KRSRSRSRSRGRGSEKRK--------- 148 Query: 451 GDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR 510 K ++K +SR+ S +++ K+K SS S S + S S +S GR Sbjct: 149 --KKSRKDTSRNC-SASTSQERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGR 205 Score = 31.6 bits (70), Expect = 2.2 Identities = 30/154 (19%), Positives = 64/154 (41%), Gaps = 2/154 (1%) Query: 282 GAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTK 341 G+ A + + A A+S P + A G + G +G MA G+ + + ++ Sbjct: 79 GSGAALPSRPASRAAPRPEASSPPLPLEKARGGLSGPQGGRARGAMAHVGSRKRSRSRSR 138 Query: 342 VAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSK 401 G+ + + S + S S S + RT + + +++ S+ S Sbjct: 139 SRGRGSEKRKKKSRKDTSRNCS--ASTSQERSKQKARRRTRSSSSSSSSSSSSSSSSSSS 196 Query: 402 SSLSGQHGRERTQASAEGCKEGRERREKDRALGR 435 SS S GR++ + ++ +++R+K + G+ Sbjct: 197 SSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGK 230 >gi|24497554 homeobox A13 [Homo sapiens] Length = 388 Score = 46.6 bits (109), Expect = 6e-05 Identities = 41/116 (35%), Positives = 48/116 (41%), Gaps = 16/116 (13%) Query: 278 AAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAP 337 AAAA AAA AA G G AA +A G S A A AA A N+ +A A +AP Sbjct: 40 AAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAP 99 Query: 338 NSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGP 393 GAA SA S E S A A + AA A ++ GP Sbjct: 100 --------GAA--------SAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGP 139 Score = 36.6 bits (83), Expect = 0.067 Identities = 38/154 (24%), Positives = 56/154 (36%), Gaps = 6/154 (3%) Query: 240 GGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVA 299 GG + ++ NK A+ + A GG AAA A + A A + A Sbjct: 23 GGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAA 82 Query: 300 AANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSAS 359 AAN Q +A A + G + G A P++ A A AA ++ +S+S Sbjct: 83 AAN----QCRNLMAHPAPLAPGAASAYSSAPGEA--PPSAAAAAAAAAAAAAAAAAASSS 136 Query: 360 MSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGP 393 G A AA++ AA P Sbjct: 137 GGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALP 170 Score = 31.6 bits (70), Expect = 2.2 Identities = 25/95 (26%), Positives = 35/95 (36%) Query: 228 SEVCGATSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGA 287 S A +AA A +N P + + S+ E P + AAAA AAA A Sbjct: 71 SVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAA 130 Query: 288 ATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGG 322 A + +G A A + AA + G Sbjct: 131 AAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSG 165 >gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapiens] Length = 674 Score = 46.2 bits (108), Expect = 8e-05 Identities = 57/239 (23%), Positives = 89/239 (37%), Gaps = 9/239 (3%) Query: 273 GGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGT 332 GG E AAA AAA AA+G G P A A + + + + + Sbjct: 333 GGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSS 392 Query: 333 ASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAG 392 S + +S++ G +S H S S S SR S S SR+ + + G Sbjct: 393 RSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRY------SRSRSRGRRHSGGG 446 Query: 393 PPVSTRQSKS-SLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRG 451 R S+S + G +G R S + R RR SS R R+ S +R Sbjct: 447 SRDGHRYSRSPARRGGYGPRRRSRSRSHSGD-RYRRGGRGLRHHSSSRSRSSWSLSPSRS 505 Query: 452 DKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR 510 + + S S S +R + + +P +R + + S K +T +G+ Sbjct: 506 RSLTRSRSHSPSPSQSRSRSRSRSQS-PSPSPAREKLTRPAASPAVGEKLKKTEPAAGK 563 >gi|57864582 hornerin [Homo sapiens] Length = 2850 Score = 45.8 bits (107), Expect = 1e-04 Identities = 67/331 (20%), Positives = 127/331 (38%), Gaps = 17/331 (5%) Query: 212 GKGDQDQVSIQSLHMVSEVCGATSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPA 271 G G Q S QS V G+ ++ G G + ++ + +TS E Sbjct: 295 GHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESG 354 Query: 272 TGGIKEAAAAGAAAGAAT-----GTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGN 326 +G + G+ +G ++ G+ +G S + + + + S++ + + Sbjct: 355 SGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRG 414 Query: 327 MALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSR----EGSVSLAIAGVVLTSRTA 382 +G+ + + + +G + S +H + S S GS + G +S Sbjct: 415 QHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEH 474 Query: 383 AEADMDAAAGPPVSTRQSK-SSLSGQHGRERTQASAEGCKE--GRERREKDRALGRSSHR 439 + +G S+ + S SGQ R Q S+ G G+ ++LG S H Sbjct: 475 SSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHG 534 Query: 440 RRTGESRHKTRG--DKIAQKSSSRSSFSHRANRDDKK---EKGCGNPGSSRHRDSHKGVS 494 +G+S +RG + +++SSS + + R + E G G+ H++S G S Sbjct: 535 SGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQS 594 Query: 495 HTPISKESRTSHKSGRSLWTTSSGSSKGLGR 525 S + H S ++SG S G+ Sbjct: 595 SGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQ 625 Score = 44.7 bits (104), Expect = 2e-04 Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 1/127 (0%) Query: 402 SSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSR 461 SS GQHG QAS+ G R+ S+ R +G +H + G + R Sbjct: 371 SSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSS-GSGQSPGHGQR 429 Query: 462 SSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSK 521 S S ++ + G G SS S G S ES + H SG + + SG S Sbjct: 430 GSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSS 489 Query: 522 GLGRVSS 528 G G+ S Sbjct: 490 GHGQHGS 496 Score = 44.7 bits (104), Expect = 2e-04 Identities = 56/234 (23%), Positives = 89/234 (38%), Gaps = 24/234 (10%) Query: 299 AAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKV--AVAGAAGKSSEHVS 356 +++N G VS +G G + G+ S + + + +G + +S +H S Sbjct: 685 SSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGS 744 Query: 357 SASMSLS--REGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQ 414 S+ +S S + GS S +G + + G + SS GQHG + Sbjct: 745 SSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHG----SSSGHSSSHGQHGSGTSC 800 Query: 415 ASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKK 474 +S+ G E +A G H +G+ +Q S+ FS + Sbjct: 801 SSSCGHYESGS----GQASGFGQHESGSGQG--------YSQHGSASGHFSSQGRHGSTS 848 Query: 475 EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSS 528 G SS DS G S + ES + H SGR + SG S G G+ S Sbjct: 849 ----GQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGS 898 Score = 43.1 bits (100), Expect = 7e-04 Identities = 55/215 (25%), Positives = 81/215 (37%), Gaps = 18/215 (8%) Query: 321 GGNKGNMALAGT-ASMAPNSTKVAVAGAA-GKSSEHV-----SSASMSLSREGSVSLAIA 373 G + G+ + G S + S+ GA+ G+SS H SS S R+GS S Sbjct: 1067 GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 1126 Query: 374 GVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRAL 433 G + ++ G + +SS SGQHG ++S G E + + Sbjct: 1127 GHGQRGSGSRQSPSYGRHG----SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 1182 Query: 434 GRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGV 493 S +G +H G + Q S S + + G G+ SS H G Sbjct: 1183 HGSGSGHSSGYGQH---GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS 1239 Query: 494 SHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSS 528 H+P SR H SG ++ G GR SS Sbjct: 1240 GHSP----SRGRHGSGLGHSSSHGQHGSGSGRSSS 1270 Score = 42.7 bits (99), Expect = 0.001 Identities = 55/215 (25%), Positives = 81/215 (37%), Gaps = 18/215 (8%) Query: 321 GGNKGNMALAGT-ASMAPNSTKVAVAGAA-GKSSEHV-----SSASMSLSREGSVSLAIA 373 G + G+ + G S + S+ GA+ G+SS H SS S R+GS S Sbjct: 2007 GSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 2066 Query: 374 GVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRAL 433 G + ++ G + +SS SGQHG ++S G E + + Sbjct: 2067 GHGQRGSGSRQSPSYGRHG----SGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQ 2122 Query: 434 GRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGV 493 S +G +H G + Q S S + + G G+ SS H G Sbjct: 2123 HGSGSGHSSGYGQH---GSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGS 2179 Query: 494 SHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSS 528 H+P SR H SG ++ G GR SS Sbjct: 2180 GHSP----SRGRHGSGSGHSSSHGQHGSGSGRSSS 2210 Score = 40.8 bits (94), Expect = 0.004 Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 9/134 (6%) Query: 397 TRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQ 456 +R +SS S QHG +S+ G + G R+ +LG H +G+S +RG + Sbjct: 962 SRSGQSSRSEQHGSSSGSSSSYG-QHGSGSRQ---SLGHGQHGSGSGQSPSPSRGRHGSG 1017 Query: 457 KSSSRSSFSHRANRDDKK-----EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511 S S +R+ E G G+ HR+S G S S + H S Sbjct: 1018 SGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 1077 Query: 512 LWTTSSGSSKGLGR 525 ++SG S G+ Sbjct: 1078 QHGSTSGQSSSCGQ 1091 Score = 40.0 bits (92), Expect = 0.006 Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 7/137 (5%) Query: 396 STRQSKSSLSGQHGRERTQASAEGCKE--GRERREKDRALGRSSHRRRTGESRHKTRG-- 451 S+ + S SGQ R S+ G G+ ++LG H +G+S +RG Sbjct: 2365 SSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 2424 Query: 452 DKIAQKSSSRSSFSHRANRDDKK---EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKS 508 + +SSS S + + + E G G+ HR+S G S S + H S Sbjct: 2425 GSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2484 Query: 509 GRSLWTTSSGSSKGLGR 525 ++SG S G+ Sbjct: 2485 THGQHGSTSGQSSSCGQ 2501 Score = 40.0 bits (92), Expect = 0.006 Identities = 54/215 (25%), Positives = 80/215 (37%), Gaps = 18/215 (8%) Query: 321 GGNKGNMALAGT-ASMAPNSTKVAVAGAA-GKSSEHV-----SSASMSLSREGSVSLAIA 373 G + G+ + G S + S+ GA+ G+SS H SS S R+GS S Sbjct: 2477 GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 2536 Query: 374 GVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRAL 433 G + ++ G + +SS SGQHG ++S G E + + Sbjct: 2537 GHGQRGSGSRQSPSYGRHG----SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 2592 Query: 434 GRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGV 493 S +G +H G + Q S S + + G G+ SS H G Sbjct: 2593 HGSGSGHSSGYGQH---GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS 2649 Query: 494 SHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSS 528 +P SR H SG ++ G GR SS Sbjct: 2650 GQSP----SRGRHGSGLGHSSSHGQHGSGSGRSSS 2680 Score = 39.7 bits (91), Expect = 0.008 Identities = 57/219 (26%), Positives = 86/219 (39%), Gaps = 26/219 (11%) Query: 321 GGNKGNMALAGT-ASMAPNSTKVAVAGAA-GKSSEHV-----SSASMSLSREGSVSLAIA 373 G + G+ + G S + S+ GA+ G+SS H SS S R+GS S Sbjct: 1537 GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 1596 Query: 374 GVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRAL 433 G + ++ G + +SS SGQHG ++S G E + + Sbjct: 1597 GHGQRGSGSRQSPSYGRHG----SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 1652 Query: 434 GRSSHRRRTGESRHKTRGDKIAQ----KSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDS 489 S +G +H +R + ++ SSSRSS + + G G+ SS H Sbjct: 1653 HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRY-------GQHGSGSRQSSGHGRQ 1705 Query: 490 HKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSS 528 G +P SR H SG ++ G GR SS Sbjct: 1706 GSGSGQSP----SRGRHGSGLGHSSSHGQHGSGSGRSSS 1740 Score = 38.9 bits (89), Expect = 0.013 Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 9/134 (6%) Query: 397 TRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQ 456 +R +SS QHG +S+ G + G R+ +LG H +G+S +RG + Sbjct: 1902 SRSGQSSRGEQHGSSSGSSSSYG-QHGSGSRQ---SLGHGQHGSGSGQSPSPSRGRHGSG 1957 Query: 457 KSSSRS-----SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511 S S S S ++ E G G+ HR+S G S S + H S Sbjct: 1958 SGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 2017 Query: 512 LWTTSSGSSKGLGR 525 ++SG S G+ Sbjct: 2018 QHGSASGQSSSCGQ 2031 Score = 38.5 bits (88), Expect = 0.018 Identities = 62/277 (22%), Positives = 98/277 (35%), Gaps = 25/277 (9%) Query: 274 GIKEAAAAGAAAGAATGTVAGAL-SVAAANSAPGQVSA-----AIAGAATIDAGGNKGNM 327 G E+ + ++A + G+ +G S S GQ S + G ++ G+ Sbjct: 1285 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSS 1344 Query: 328 ALAGTASMAPNSTKVAVAGAAGKSSEHVSSA---------SMSLSREGSVSLAIAGV--- 375 +G S + G G S H SS S S R GS S +G Sbjct: 1345 QSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1404 Query: 376 VLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKE--GRERREKDRAL 433 +S ++ + S+ + S SGQ R S+ G G+ ++L Sbjct: 1405 ESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSL 1464 Query: 434 GRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSR-----HRD 488 G H +G+S +RG + S S + + +G GSS HR+ Sbjct: 1465 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRE 1524 Query: 489 SHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGR 525 S G S S + H S ++SG S G+ Sbjct: 1525 SRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQ 1561 Score = 38.1 bits (87), Expect = 0.023 Identities = 38/146 (26%), Positives = 55/146 (37%), Gaps = 23/146 (15%) Query: 401 KSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESR-HKTRGDKIAQKSS 459 +SS SG+HG Q+S G K ++ G + H +G S ++ G + Q S Sbjct: 915 RSSSSGRHGSGSGQSSGFGHKSS-----SGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 969 Query: 460 SRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSL------- 512 S S + + G G+ S H G +P R SG+S Sbjct: 970 SEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRS 1029 Query: 513 ---WTTS-------SGSSKGLGRVSS 528 W++S SG S GLG S Sbjct: 1030 GSGWSSSRGPYESGSGHSSGLGHRES 1055 Score = 37.0 bits (84), Expect = 0.051 Identities = 44/186 (23%), Positives = 68/186 (36%), Gaps = 20/186 (10%) Query: 345 AGAAGKSSEHVSSA--SMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKS 402 +G + + H SS+ S S + GS S G + ++ G + S Sbjct: 264 SGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHG----SGSGHS 319 Query: 403 SLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRS 462 S GQHG + + + G E + S + +G S+H + S S Sbjct: 320 SSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGS--------GSGHS 371 Query: 463 SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKG 522 S + + G GSS + S G ES + H SGR ++ SG S G Sbjct: 372 SSQGQHGSTSGQASSSGQHGSSSRQSSSYG------QHESASRHSSGRGQHSSGSGQSPG 425 Query: 523 LGRVSS 528 G+ S Sbjct: 426 HGQRGS 431 Score = 36.6 bits (83), Expect = 0.067 Identities = 48/204 (23%), Positives = 76/204 (37%), Gaps = 20/204 (9%) Query: 330 AGTASMAPNSTKVAVAGAAGKSSEHVSSASMS--LSREGSVSLAIAGVVLTSRTAAEADM 387 +G+ + N T + +G + S+H SS+ S S+ GS S +G + ++ Sbjct: 210 SGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQS-- 267 Query: 388 DAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRH 447 + G + SS GQHG Q+ G ++G R+ SH R S H Sbjct: 268 --SRGERHRSSSGSSSSYGQHGSGSRQSLGHG-RQGSGSRQSP------SHVRHGSGSGH 318 Query: 448 KTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHK 507 + + SS S H E G G +S G S S + H Sbjct: 319 SSSHGQHGSGSSYSYSRGHY-------ESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHS 371 Query: 508 SGRSLWTTSSGSSKGLGRVSSFLR 531 S + ++SG + G+ S R Sbjct: 372 SSQGQHGSTSGQASSSGQHGSSSR 395 Score = 36.6 bits (83), Expect = 0.067 Identities = 45/184 (24%), Positives = 66/184 (35%), Gaps = 16/184 (8%) Query: 353 EHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRER 412 E S S S S+ GS S +G + ++ G + SS GQHG Sbjct: 1171 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG----SSSGSSSHYGQHGSGS 1226 Query: 413 TQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDD 472 Q+S G R+ + R H G S + + +SSSR + R+ Sbjct: 1227 RQSSGHG----RQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSS 1282 Query: 473 ---KKEKGCGNPGSSRHRDSHKG-----VSHTPISKESRTSHKSGRSLWTTSSGSSKGLG 524 + E G G+ + S G H S +S T + G S +SS +G G Sbjct: 1283 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSG 1342 Query: 525 RVSS 528 S Sbjct: 1343 SSQS 1346 Score = 36.6 bits (83), Expect = 0.067 Identities = 45/184 (24%), Positives = 66/184 (35%), Gaps = 16/184 (8%) Query: 353 EHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRER 412 E S S S S+ GS S +G + ++ G + SS GQHG Sbjct: 1641 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG----SSSRSSSRYGQHGSGS 1696 Query: 413 TQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDD 472 Q+S G R+ ++ R H G S + + +SSSR + R+ Sbjct: 1697 RQSSGHG----RQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSS 1752 Query: 473 ---KKEKGCGNPGSSRHRDSHKG-----VSHTPISKESRTSHKSGRSLWTTSSGSSKGLG 524 + E G G+ + S G H S +S T + G S +SS G G Sbjct: 1753 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSG 1812 Query: 525 RVSS 528 S Sbjct: 1813 SSQS 1816 Score = 36.2 bits (82), Expect = 0.087 Identities = 45/184 (24%), Positives = 66/184 (35%), Gaps = 16/184 (8%) Query: 353 EHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRER 412 E S S S S+ GS S +G + ++ G + SS GQHG Sbjct: 2581 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG----SSSGSSSHYGQHGSGS 2636 Query: 413 TQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDD 472 Q+S G R+ ++ R H G S + + +SSSR + R Sbjct: 2637 RQSSGHG----RQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSS 2692 Query: 473 ---KKEKGCGNPGSSRHRDSHKG-----VSHTPISKESRTSHKSGRSLWTTSSGSSKGLG 524 + E G G+ + S G H S +S T + G S +SS +G G Sbjct: 2693 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSG 2752 Query: 525 RVSS 528 S Sbjct: 2753 SSQS 2756 Score = 35.8 bits (81), Expect = 0.11 Identities = 43/157 (27%), Positives = 63/157 (40%), Gaps = 33/157 (21%) Query: 402 SSLSGQHGRERTQASAEGCKEGRERR-----EKDRALGRSS----HRRRTGESRHKTRGD 452 SS SG+HG Q+S G E + + G SS H R+G+S +RG+ Sbjct: 1385 SSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQS---SRGE 1441 Query: 453 KIAQKSSSRSSFSHRANRDDKK----EKGCGN-----PGSSRHRD-SHKGVSHTPISK-- 500 + S S SS+ + + + G G+ P RH S + S++P Sbjct: 1442 RHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS 1501 Query: 501 ---------ESRTSHKSGRSLWTTSSGSSKGLGRVSS 528 ES +SH SG + SG S G G+ S Sbjct: 1502 GWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGS 1538 Score = 35.4 bits (80), Expect = 0.15 Identities = 56/238 (23%), Positives = 84/238 (35%), Gaps = 43/238 (18%) Query: 321 GGNKGNMALAGT--ASMAPNSTKVAVAGAAGKSSEHV-----SSASMSLSREGSVSLAIA 373 G G+ G ++ +ST + G+SS H SS S S ++GS S Sbjct: 1771 GSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS---- 1826 Query: 374 GVVLTSRTAAEADMDAAAGPPVSTRQSKS-----SLSGQHGRERTQASAEGCKEGRERRE 428 ++ + + +G S Q S S SG+HG Q+S G E + Sbjct: 1827 -----GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS 1881 Query: 429 KDRALGRSSHRRRTGESR-HKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHR 487 G + H +G S ++ G + Q S S + + G G+ S H Sbjct: 1882 S----GYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHG 1937 Query: 488 DSHKGVSHTPISKESRTSHKSGRSL----------WTTS-------SGSSKGLGRVSS 528 G +P R SG+S W++S SG S GLG S Sbjct: 1938 QHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRES 1995 Score = 34.7 bits (78), Expect = 0.25 Identities = 61/250 (24%), Positives = 94/250 (37%), Gaps = 54/250 (21%) Query: 321 GGNKGNMALAGT--ASMAPNSTKVAVAGAAGKSSEHV-----SSASMSLSREGSVSLAIA 373 G G+ G ++ +ST + G+SS H SS S S ++GS S Sbjct: 2241 GSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS---- 2296 Query: 374 GVVLTSRTAAEADMDAAAGPPVSTRQSKS-----SLSGQHGRERTQASAEGCKEGRERR- 427 ++ + + +G S Q S S SG+HG Q+S G E + Sbjct: 2297 -----GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS 2351 Query: 428 ----EKDRALGRSS----HRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKK----E 475 + G SS H R+G+S +RG++ S S SS+ + + + Sbjct: 2352 SGYTQHGSGSGHSSSYEQHGSRSGQS---SRGERHGSSSGSSSSYGQHGSGSRQSLGHGQ 2408 Query: 476 KGCGN-----PGSSRHRD-SHKGVSHTPISK-----------ESRTSHKSGRSLWTTSSG 518 G G+ P RH S + S++P ES + H SG + SG Sbjct: 2409 HGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSG 2468 Query: 519 SSKGLGRVSS 528 S G G+ S Sbjct: 2469 QSSGYGQHGS 2478 Score = 34.3 bits (77), Expect = 0.33 Identities = 46/181 (25%), Positives = 63/181 (34%), Gaps = 42/181 (23%) Query: 345 AGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSL 404 +G A +H S + S+ GS S +++ + +G +SS Sbjct: 811 SGQASGFGQHESGSGQGYSQHGSAS---------GHFSSQGRHGSTSG--------QSSS 853 Query: 405 SGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESR-HKTRGDKIAQKSSSRSS 463 SGQH Q+S+ G E A GR H +G+S H RG Q S Sbjct: 854 SGQHDSSSGQSSSYGQHESASHH----ASGRGRHGSGSGQSPGHGQRGSGSGQSPSY--- 906 Query: 464 FSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHK--SGRSLWTTSSGSSK 521 G GS R S G + + S HK SG+S T GS Sbjct: 907 ---------------GRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGS 951 Query: 522 G 522 G Sbjct: 952 G 952 Score = 33.5 bits (75), Expect = 0.57 Identities = 51/211 (24%), Positives = 73/211 (34%), Gaps = 44/211 (20%) Query: 345 AGAAGKSSEHVSSASMSL--SREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKS 402 AG++ +H S + SL SR GS S ++ + +RQS S Sbjct: 511 AGSSSSYGQHGSGSRQSLGHSRHGSGS-------------GQSPSPSRGRHESGSRQSSS 557 Query: 403 SLSGQHGRERTQASAEGCKE---------GRERREKDRALGRSSHRRRTGESR-HKTRGD 452 G HG ++S+ G E G + ++ G H +G S H G Sbjct: 558 Y--GPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGS 615 Query: 453 KIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPI---------SKESR 503 Q SS + + G G+ SSR+ G +P S Sbjct: 616 TSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSY 675 Query: 504 TSHKSGRSLWTTS-------SGSSKGLGRVS 527 H SG S W++S SG S G G S Sbjct: 676 GQHGSG-SGWSSSNGPHGSVSGQSSGFGHKS 705 Score = 29.6 bits (65), Expect = 8.2 Identities = 54/256 (21%), Positives = 89/256 (34%), Gaps = 12/256 (4%) Query: 274 GIKEAAAAGAAAGAATGTVAGALSVAAAN-SAPGQVSA-----AIAGAATIDAGGNKGNM 327 G +E+ + ++ G+ +G S + SA GQ S+ A +G ++ G+ Sbjct: 1991 GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSS 2050 Query: 328 ALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADM 387 +G S + G G S S S G S + ++ Sbjct: 2051 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHH 2110 Query: 388 DAAAGPPVSTRQ-----SKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRT 442 ++++G S Q SS GQHG R+ S+ G + G R S R++ Sbjct: 2111 ESSSGQSSSYSQHGSGSGHSSGYGQHG-SRSGQSSRGERHGSSSGSSSRYGQHGSGSRQS 2169 Query: 443 GESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKES 502 + G + S S ++ + G G S +S G S ES Sbjct: 2170 SGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHES 2229 Query: 503 RTSHKSGRSLWTTSSG 518 + H S S + SG Sbjct: 2230 GSGHSSAYSQHGSGSG 2245 >gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo sapiens] Length = 434 Score = 45.4 bits (106), Expect = 1e-04 Identities = 45/173 (26%), Positives = 76/173 (43%), Gaps = 16/173 (9%) Query: 350 KSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEA-----DMDAAAGPPVSTRQSKSSL 404 ++S+H S S S SRE G SR+ ++ D ++ S + Sbjct: 34 RASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEH 93 Query: 405 SGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRG---------DKIA 455 S GRER +S G ++ +R+E+ + GRS R R+ E RH++R + Sbjct: 94 SSDKGRERLNSSENG-EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRER 152 Query: 456 QKSSSRSSFSHRA-NRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHK 507 +KS SRS ++ +R ++++ + SR R H+ S + SR K Sbjct: 153 KKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKK 205 Score = 37.0 bits (84), Expect = 0.051 Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 28/151 (18%) Query: 398 RQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGR-----------SSHRRR----- 441 R+ KS G+ R R+++ KEGR KD++ + SS + R Sbjct: 50 RKRKSDNEGRKHRSRSRS-----KEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNS 104 Query: 442 --TGESRHKTRGDKIAQ-KSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPI 498 GE RHK + K ++ +S SRS R +R +E+ SR R+ K S + Sbjct: 105 SENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRER---KKSRSRSRERKKSRSRSRE 161 Query: 499 SKESRT-SHKSGRSLWTTSSGSSKGLGRVSS 528 K+SR+ S + R + + S S+ R S Sbjct: 162 RKKSRSRSRERKRRIRSRSRSRSRHRHRTRS 192 >gi|60097902 filaggrin [Homo sapiens] Length = 4061 Score = 45.1 bits (105), Expect = 2e-04 Identities = 77/334 (23%), Positives = 128/334 (38%), Gaps = 57/334 (17%) Query: 281 AGAAAGAATGT---VAGALSVAAANSAPGQVSAAIAGAATIDAG--GNKGNMALAGTASM 335 A ++AG G+ + A S + + GQ S+A+ D+G G+ G+ A Sbjct: 700 ARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVR-----DSGHRGSSGSQATDSEGHS 754 Query: 336 APNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAA-AGPP 394 + T+ +V+G S + R G S + T +++ GP Sbjct: 755 EDSDTQ-SVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPS 813 Query: 395 VSTRQ----------SKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGE 444 RQ S+ S S Q G++ + + GR+ ++++ RS H + Sbjct: 814 TGVRQGSHHEQARDNSRHSAS-QDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGH-SGSHH 871 Query: 445 SRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKE--- 501 S ++G A + S S + R R++++ + SRH H+ SH IS+ Sbjct: 872 SHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRH---HEASSHADISRHSQA 928 Query: 502 -------SRTSHKSGRSLW--TTSSGSSKGLGRVS-SFLRNVRANLTTK----------- 540 SRTS + G S+ + S G S+ R S S RN R + + Sbjct: 929 GQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSH 988 Query: 541 -VVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQ 573 HG D + R + AET+ GGQ Sbjct: 989 HEDRAGHGHSAD-----SSRQSGTPHAETSSGGQ 1017 Score = 44.3 bits (103), Expect = 3e-04 Identities = 52/234 (22%), Positives = 94/234 (40%), Gaps = 22/234 (9%) Query: 276 KEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASM 335 +++ +A AG +TG G+ A +S+ + SA+ G TI G+ G+ G Sbjct: 3718 EQSESAHGRAGPSTGGRQGSRHEQARDSS--RHSASQEGQDTIR--GHPGSRR--GGRQG 3771 Query: 336 APNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPV 395 + + V +G +G H +S S + G +G SR + Sbjct: 3772 SYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQ-----SGSRSASRETRNEEQSGDGSRHS 3826 Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455 +R ++S R E R RR+ G S + E+ + + Sbjct: 3827 GSRHHEASTQADSSRHSQSGQGESAGSRRSRRQ-----GSSVSQDSDSEAYPED-----S 3876 Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSG 509 ++ S +S +H + ++ G +PGSS HRD+ V +P+ +S T+ + G Sbjct: 3877 ERRSESASRNHHGSSREQSRDGSRHPGSS-HRDTASHVQSSPVQSDSSTAKEHG 3929 Score = 39.3 bits (90), Expect = 0.010 Identities = 46/204 (22%), Positives = 73/204 (35%), Gaps = 19/204 (9%) Query: 317 TIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSS---EHVSSASMSLSREGSVSLAIA 373 T G + + +G+ S + + +G + S H +S +SR S A+ Sbjct: 2819 TTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRH---SQAVQ 2875 Query: 374 GVVLTSR------TAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERR 427 G SR ++ D D+ S R S S+ HG + Q +G + R + Sbjct: 2876 GQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLR-DGSRHPRSHQ 2934 Query: 428 EKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHR 487 E G S+ R +RH S +++ SH R E+ + S Sbjct: 2935 EDRAGHGHSADSSRQSGTRHTQTS------SGGQAASSHEQARSSAGERHGSHHQQSADS 2988 Query: 488 DSHKGVSHTPISKESRTSHKSGRS 511 H G+ H S R S G S Sbjct: 2989 SRHSGIGHGQASSAVRDSGHRGYS 3012 Score = 38.9 bits (89), Expect = 0.013 Identities = 41/170 (24%), Positives = 57/170 (33%), Gaps = 21/170 (12%) Query: 351 SSEHVSSASMSLSREGSVSLAIAGVVLTSR---TAAEADMDAAAGPPVSTRQSKSSLSGQ 407 S H +S+ SR V + TSR ++ D D+ S R S S+ Sbjct: 586 SRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNH 645 Query: 408 HGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHR 467 HG + Q S +G + R S H R G K + + SS Sbjct: 646 HGSAQEQ-SRDGSRHPR-----------SHHEDRAGHGHSADSSRKSGTRHTQNSSSGQA 693 Query: 468 ANRDDKKEKGCGNPGSSRHR------DSHKGVSHTPISKESRTSHKSGRS 511 A+ ++ G SRH+ H G H S R S G S Sbjct: 694 ASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSS 743 Score = 38.9 bits (89), Expect = 0.013 Identities = 50/196 (25%), Positives = 72/196 (36%), Gaps = 13/196 (6%) Query: 332 TASMAPNSTKVAVAGAAGKSSEHVSSASMS-LSREGSVSLAIAGVVLTSR---TAAEADM 387 +AS K + G+ S H +AS + SR V + TSR ++ D Sbjct: 1215 SASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDS 1274 Query: 388 DAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRH 447 D+ S R S S+ HG R Q S +G + +E + G S+ R + H Sbjct: 1275 DSERHSDDSERLSGSASRNHHGSSREQ-SRDGSRHPGFHQEDRASHGHSADSSRQSGTHH 1333 Query: 448 KTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTS-H 506 S ++ SH R E+ S H G+ H S R S H Sbjct: 1334 TE------SSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGH 1387 Query: 507 K-SGRSLWTTSSGSSK 521 + S S T S G S+ Sbjct: 1388 RGSSGSQVTNSEGHSE 1403 Score = 38.1 bits (87), Expect = 0.023 Identities = 55/276 (19%), Positives = 105/276 (38%), Gaps = 24/276 (8%) Query: 265 ELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIA--------GAA 316 E + T E A + +G A S + + GQ S+A++ G+ Sbjct: 362 ETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQ 421 Query: 317 TIDAGGNKGN-----MALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLA 371 D+ G+ N ++ G A + S + + G +G+ S S+ +S A Sbjct: 422 ASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSA 481 Query: 372 IAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDR 431 G TS + A R S + Q G++ + + GR+ ++ Sbjct: 482 -HGRTGTSTGGRQGSHHEQA------RDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQ 534 Query: 432 ALGRSSHR-RRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSH 490 ++ RS H + + R D +S SRS+ S + +++ G + GS H S Sbjct: 535 SVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSA-SRQTRNEEQSGDGTRHSGSRHHEASS 593 Query: 491 KGVS--HTPISKESRTSHKSGRSLWTTSSGSSKGLG 524 + S H+ + + + ++ R+ ++ S S G Sbjct: 594 QADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQG 629 Score = 38.1 bits (87), Expect = 0.023 Identities = 83/351 (23%), Positives = 136/351 (38%), Gaps = 66/351 (18%) Query: 269 EPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAP------GQVSAAIA-----GAAT 317 E ++GG +AA++ A ++ G G+ +A+S+ GQ S+A+ G++ Sbjct: 3280 ETSSGG--QAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSG 3337 Query: 318 IDAGGNKGNMALAGTASMAPNSTKVAVAGAAG--KSSEHVSSASMSLSREGSVSLAIAGV 375 A ++G+ + T S++ + G AG + S S+ S R G +G Sbjct: 3338 SQASDSEGHSEESDTQSVSGH-------GQAGPHQQSHQESARDRSGGRSGR-----SGS 3385 Query: 376 VLTSRTAAEADMDAAAGPPVST-----------RQSKSSLSGQHGRERTQASAEGCKEGR 424 L + E A ST R S + Q G++ + + GR Sbjct: 3386 FLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGR 3445 Query: 425 ERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKK---------- 474 + ++++ RS H + S ++G A + S S + R R+D++ Sbjct: 3446 QGSHYEQSVDRSGH-SGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWS 3504 Query: 475 --EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLW--TTSSGSSKGLGRVS-SF 529 + SSRH S +G S P RTS G S+ + S G S+ R S S Sbjct: 3505 HHHEASTQADSSRHSQSGQGQSAGP-----RTSRNQGSSVSQDSDSQGHSEDSERWSGSA 3559 Query: 530 LRNVRANLTTKVVG-----TPHGRDVDVMAKMAE--RSTNVAIAETAEGGQ 573 RN R + + T H D AE R + AE + GGQ Sbjct: 3560 SRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQ 3610 Score = 37.7 bits (86), Expect = 0.030 Identities = 59/265 (22%), Positives = 104/265 (39%), Gaps = 26/265 (9%) Query: 269 EPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQ-VSAAIAGAATIDAG--GNKG 325 E ++GG +AA++ A ++ G G+ +A+S+ + A +A D+G G+ G Sbjct: 1011 ETSSGG--QAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSG 1068 Query: 326 NMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEA 385 + A + T+ +V+G G+ H S S +G + + E Sbjct: 1069 SQASDSEGHSEESDTQ-SVSGH-GQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQ 1126 Query: 386 DMDAAAGPPVST-----------RQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALG 434 A ST R S + Q G++ +A + GR+ ++++ Sbjct: 1127 SESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVD 1186 Query: 435 RSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVS 494 RS H + S ++G A S S + R R DK+ SRH ++ Sbjct: 1187 RSGH-SGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWAD 1245 Query: 495 ---HTPISKE----SRTSHKSGRSL 512 H+ + +E SRTS G S+ Sbjct: 1246 SSRHSQVGQEQSSGSRTSRHQGSSV 1270 Score = 37.0 bits (84), Expect = 0.051 Identities = 39/164 (23%), Positives = 58/164 (35%), Gaps = 10/164 (6%) Query: 351 SSEHVSSASMSLSREGSVSLAIAGVVLTSR---TAAEADMDAAAGPPVSTRQSKSSLSGQ 407 S H +S+ S V + TSR ++ D D+ S R S S+ Sbjct: 2532 SRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNH 2591 Query: 408 HGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHR 467 HG + Q +G + R +E G S+ R +RH S +++ SH Sbjct: 2592 HGSAQEQLR-DGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTS------SGGQAASSHE 2644 Query: 468 ANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511 R E+ + S H G+ H S R S G S Sbjct: 2645 QARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYS 2688 Score = 36.6 bits (83), Expect = 0.067 Identities = 38/172 (22%), Positives = 66/172 (38%), Gaps = 20/172 (11%) Query: 346 GAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLS 405 G+A + S H S S +E S + A+ + S Q++SS Sbjct: 1620 GSAREQSRHGSRNPRS-HQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPG 1678 Query: 406 GQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFS 465 +HG Q++ G RR+ +G S +R +G + G +++S ++S + Sbjct: 1679 ERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGH--SEESDTQSVSA 1736 Query: 466 HRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSS 517 H G P H++S +G S S +SG L+ S+ Sbjct: 1737 H----------GQAGPHQQSHQESTRGQS-------GERSGRSGSFLYQVST 1771 Score = 36.6 bits (83), Expect = 0.067 Identities = 40/169 (23%), Positives = 58/169 (34%), Gaps = 20/169 (11%) Query: 351 SSEHVSSASMSLSREGSVSLAIAGVVLTSR---TAAEADMDAAAGPPVSTRQSKSSLSGQ 407 S H +S+ SR V + TSR ++ D D+ S R+S S+ Sbjct: 2208 SHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNH 2267 Query: 408 HGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHR 467 HG + Q S +G + R S H R G + + SS Sbjct: 2268 HGSAQEQ-SRDGSRHPR-----------SHHEDRAGHGHSAESSRQSGTHHAENSSGGQA 2315 Query: 468 ANRDDKKEKGCGNPGSSRHRDS-----HKGVSHTPISKESRTSHKSGRS 511 A+ ++ G S H+ S H G+ H S R S G S Sbjct: 2316 ASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSS 2364 Score = 34.3 bits (77), Expect = 0.33 Identities = 41/167 (24%), Positives = 58/167 (34%), Gaps = 15/167 (8%) Query: 351 SSEHVSSASMSLSREGSVSLAIAGVVLTSR---TAAEADMDAAAGPPVSTRQSKSSLSGQ 407 S H +S+ SR V + TSR ++ D D+ S R S S+ S Sbjct: 1883 SRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSA-SRN 1941 Query: 408 HGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRH---KTRGDKIAQKSSSRSSF 464 H + S +G + E G S+ R +RH +RG + +RSS Sbjct: 1942 HLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSA 2001 Query: 465 SHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511 R G + S H G+ H S R S G S Sbjct: 2002 GER--------HGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYS 2040 Score = 34.3 bits (77), Expect = 0.33 Identities = 34/143 (23%), Positives = 49/143 (34%), Gaps = 15/143 (10%) Query: 383 AEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRT 442 +++ +AGP S Q SS+S + +E R + A +S R Sbjct: 3519 SQSGQGQSAGPRTSRNQG-SSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRH 3577 Query: 443 GESRHKTRGDKIAQKSSSRSSFSHRANRD---------DKKEKGCGNPGSSRHRDS---- 489 S H+ R SSR S +H A ++ G S H+ S Sbjct: 3578 PTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSS 3637 Query: 490 -HKGVSHTPISKESRTSHKSGRS 511 H G+ H S R S G S Sbjct: 3638 RHSGIGHGQASSAVRDSGHRGSS 3660 Score = 33.1 bits (74), Expect = 0.74 Identities = 46/208 (22%), Positives = 71/208 (34%), Gaps = 17/208 (8%) Query: 317 TIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSS---EHVSSASMSLSREGSVSLAIA 373 T G + + +G+ S + + +G + + S H +S +SR S A+ Sbjct: 3143 TTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRH---SQAVQ 3199 Query: 374 GVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEG--RERREKDR 431 G SR + S Q S ER SA G +E+ Sbjct: 3200 GQSEGSRRSRRQGS--------SVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGS 3251 Query: 432 ALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHK 491 RS H R G R + + + SS A+ ++ G SRH+ S Sbjct: 3252 RHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSAD 3311 Query: 492 GVSHTPISKESRTSHKSGRSLWTTSSGS 519 H+ I + +S W SSGS Sbjct: 3312 SSRHSGIPRGQASSAVRDSRHW-GSSGS 3338 Score = 32.7 bits (73), Expect = 0.97 Identities = 24/112 (21%), Positives = 41/112 (36%), Gaps = 1/112 (0%) Query: 396 STRQSKSSLSGQHGRERTQASAEGCKE-GRERREKDRALGRSSHRRRTGESRHKTRGDKI 454 S Q++SS +HG SA+ + G + A+ S HR +G + G Sbjct: 696 SHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSE 755 Query: 455 AQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSH 506 + S S + ++ + R R S + K+S +SH Sbjct: 756 DSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSH 807 Score = 32.7 bits (73), Expect = 0.97 Identities = 45/215 (20%), Positives = 78/215 (36%), Gaps = 17/215 (7%) Query: 317 TIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVV 376 ++D G+ G+ T+ ++++ G +G S ++ + SR+GS Sbjct: 860 SVDRSGHSGSHHSHTTSQGRSDASR----GQSGSRSASRTTRNEEQSRDGSRHSGSRHHE 915 Query: 377 LTSRTA----AEADMDAAAGPPVSTRQ----SKSSLSGQHGRERTQASAEGCKEGRERRE 428 +S ++A + G S RQ S+ S S H + + S + R + Sbjct: 916 ASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQ 975 Query: 429 KDRALG----RSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSS 484 + G RS H R G + + SS A+ ++ G S Sbjct: 976 EQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGS 1035 Query: 485 RHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGS 519 RH+ S H+ I + +S W SSGS Sbjct: 1036 RHQQSADSSRHSGIPRRQASSAVRDSGHW-GSSGS 1069 Score = 32.3 bits (72), Expect = 1.3 Identities = 28/127 (22%), Positives = 50/127 (39%), Gaps = 4/127 (3%) Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455 S Q++SS +HG Q++ G + A+ S HR +G + G + Sbjct: 2318 SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGH--S 2375 Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTT 515 + S ++S +H ++ G S R G +S ++ GR+ T Sbjct: 2376 EDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRT--GT 2433 Query: 516 SSGSSKG 522 S+G +G Sbjct: 2434 STGGRQG 2440 Score = 32.0 bits (71), Expect = 1.7 Identities = 38/145 (26%), Positives = 52/145 (35%), Gaps = 14/145 (9%) Query: 390 AAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKT 449 +AG S RQ SS+S E +E E R A +S H R S + Sbjct: 1581 SAGSKTSRRQG-SSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQED 1639 Query: 450 RGDKIAQKSSSRSSFSHRANRD------DKKEKGCGNPGSSRHRDSHKGVSHTPISKESR 503 R SSR S + A +E+ +PG RH H+ S +S Sbjct: 1640 RASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPG-ERHGSRHQQ------SADSS 1692 Query: 504 TSHKSGRSLWTTSSGSSKGLGRVSS 528 T +GR ++ G S G S Sbjct: 1693 TDSGTGRRQDSSVVGDSGNRGSSGS 1717 Score = 31.6 bits (70), Expect = 2.2 Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 19/123 (15%) Query: 396 STRQSKSSLSGQHGRERTQASAEGC---KEGRERREKDRAL----------GRSSHRRRT 442 STR+ +SG R+ + +E +E R++ +L GRS R T Sbjct: 88 STRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRET 147 Query: 443 GESRHKTRGDKIAQKSSS----RSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPI 498 G RH++ +K +K S + + KKEK ++R D+ K +S Sbjct: 148 GGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEK--NKTENTRLGDNRKRLSERLE 205 Query: 499 SKE 501 KE Sbjct: 206 EKE 208 Score = 31.6 bits (70), Expect = 2.2 Identities = 27/133 (20%), Positives = 46/133 (34%) Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455 S Q++SS +HG Q++ G RR+ A+ S H +G + G Sbjct: 1021 SHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEE 1080 Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTT 515 + S S ++ + R S + ++S ++H R+ Sbjct: 1081 SDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGR 1140 Query: 516 SSGSSKGLGRVSS 528 GS R SS Sbjct: 1141 RQGSHHEQARDSS 1153 Score = 31.6 bits (70), Expect = 2.2 Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 12/99 (12%) Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455 S Q++SS +HG Q++ G R+ A+ S HR +G + G + Sbjct: 1345 SHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGH--S 1402 Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVS 494 + S ++S +H G P H++S +G S Sbjct: 1403 EDSDTQSVSAH----------GQAGPHQQSHKESARGQS 1431 Score = 31.2 bits (69), Expect = 2.8 Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 22/116 (18%) Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455 S Q++SS +HG Q++ G + A+ S HR +G + G + Sbjct: 3614 SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGH--S 3671 Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511 + S ++S +H G P H++S +G R++ +SGRS Sbjct: 3672 EDSDTQSVSAH----------GQAGPHQQSHQESTRG----------RSAGRSGRS 3707 Score = 30.8 bits (68), Expect = 3.7 Identities = 33/177 (18%), Positives = 63/177 (35%), Gaps = 6/177 (3%) Query: 317 TIDAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSS---EHVSSASMSLSREGSVSLAIA 373 T G + + +G+ S + + +G + S H +S SR + Sbjct: 3791 TTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGES 3850 Query: 374 GVVLTSR---TAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKD 430 SR ++ D D+ A P S R+S+S+ HG R Q+ G R+ Sbjct: 3851 AGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTA 3910 Query: 431 RALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHR 487 + S + + ++ ++Q S+ S R + + G+ R + Sbjct: 3911 SHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQK 3967 Score = 30.0 bits (66), Expect = 6.3 Identities = 28/122 (22%), Positives = 44/122 (36%), Gaps = 19/122 (15%) Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455 S Q++SS +HG Q++ G + A+ S HR +G G Sbjct: 2642 SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEG---- 2697 Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTT 515 H + D + G GS H+ SH+ + + TS SG L+ Sbjct: 2698 ----------HSEDSDTQSVSAHGQAGS--HQQSHQ---ESARGRSGETSGHSGSFLYQV 2742 Query: 516 SS 517 S+ Sbjct: 2743 ST 2744 Score = 30.0 bits (66), Expect = 6.3 Identities = 28/122 (22%), Positives = 44/122 (36%), Gaps = 19/122 (15%) Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455 S Q++SS +HG Q++ G + A+ S HR +G G Sbjct: 2966 SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEG---- 3021 Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTT 515 H + D + G GS H+ SH+ + + TS SG L+ Sbjct: 3022 ----------HSEDSDTQSVSAHGQAGS--HQQSHQ---ESARGRSGETSGHSGSFLYQV 3066 Query: 516 SS 517 S+ Sbjct: 3067 ST 3068 >gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] Length = 484 Score = 43.1 bits (100), Expect = 7e-04 Identities = 61/237 (25%), Positives = 96/237 (40%), Gaps = 33/237 (13%) Query: 279 AAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPN 338 A A A AG G G L + G V A GA T+D +A G N Sbjct: 126 APANAVAGLLPG--GGLLPTPNPLTQIGAVPLAALGAPTLDPA-----LAALGLPGANLN 178 Query: 339 STKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTR 398 S +A A + + +S+ L+ V+ + L S T+++ +A R Sbjct: 179 SQSLA----ADQLLKLMSTVDPKLNH---VAAGLVSPSLKSDTSSKEIEEAMK----RVR 227 Query: 399 QSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQKS 458 +++S +S A+ E K+ E+R R+ RS RR SRH+ + ++S Sbjct: 228 EAQSLIS---------AAIEPDKK-EEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRS 277 Query: 459 SSRS-----SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR 510 S+S S S R R +E+G + +S+ RD K SK S+ + R Sbjct: 278 HSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTAR 334 Score = 31.6 bits (70), Expect = 2.2 Identities = 30/136 (22%), Positives = 52/136 (38%), Gaps = 19/136 (13%) Query: 396 STRQSKSSLSGQ-HGRER------TQASAEGCKEGRERRE------------KDRALGRS 436 S R+SKS + H RER T + + KE +E++ + R+ R Sbjct: 283 SRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRE 342 Query: 437 SHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHT 496 RRR+ + + ++ SRS R ++ KK+K R R + K Sbjct: 343 RRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSK 402 Query: 497 PISKESRTSHKSGRSL 512 K+ +S + + Sbjct: 403 DKEKDRERKSESDKDV 418 >gi|33356174 pinin, desmosome associated protein [Homo sapiens] Length = 717 Score = 43.1 bits (100), Expect = 7e-04 Identities = 38/159 (23%), Positives = 67/159 (42%), Gaps = 20/159 (12%) Query: 331 GTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAA 390 G A + ++ + ++ SS SS+S S S GS S + + +S T+ + D++ Sbjct: 564 GRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSS-SRSSSSSSSSTSGSSSRDSS 622 Query: 391 AGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTR 450 + S+ S H R+R + +R+ +D + SH+ G S T+ Sbjct: 623 SSTSSSSESRSRSRGRGHNRDRKH------RRSVDRKRRDTSGLERSHKSSKGGSSRDTK 676 Query: 451 GDK-------------IAQKSSSRSSFSHRANRDDKKEK 476 G K + +S RSS S R + D+K+K Sbjct: 677 GSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDK 715 Score = 39.3 bits (90), Expect = 0.010 Identities = 44/157 (28%), Positives = 62/157 (39%), Gaps = 21/157 (13%) Query: 356 SSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHGRERTQA 415 + S S SR S S + + S T++ + +++G S S SS S R + Sbjct: 568 NKTSKSRSRSSSSSSSSS-----SSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSS 622 Query: 416 SAEGCKEGRERREKDRALGRS-SHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKK 474 S+ R + R R HRR R T G + + KSS S +RD K Sbjct: 623 SSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGS-----SRDTKG 677 Query: 475 EKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRS 511 K N S R R IS+ SR+ +S RS Sbjct: 678 SKD-KNSRSDRKRS---------ISESSRSGKRSSRS 704 Score = 31.2 bits (69), Expect = 2.8 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 13/116 (11%) Query: 425 ERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSS 484 E + K + RS R R S+ ++R + SSS +S S ++ + GSS Sbjct: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSS---------SSSGSS 601 Query: 485 RHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTK 540 R S S T S +S S S ++S S+ GR + R R ++ K Sbjct: 602 SSRSSSSSSSSTSGS----SSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRK 653 Score = 30.0 bits (66), Expect = 6.3 Identities = 29/121 (23%), Positives = 45/121 (37%), Gaps = 6/121 (4%) Query: 408 HGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIAQ--KSSSRSSFS 465 H +++ GR R + ++ RSS + S + + SSSRSS S Sbjct: 549 HPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSS 608 Query: 466 HRANR--DDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGR--SLWTTSSGSSK 521 ++ ++ SS R +G H K R+ + R S S SSK Sbjct: 609 SSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSK 668 Query: 522 G 522 G Sbjct: 669 G 669 >gi|40068059 CBF1 interacting corepressor [Homo sapiens] Length = 450 Score = 42.0 bits (97), Expect = 0.002 Identities = 40/133 (30%), Positives = 59/133 (44%), Gaps = 12/133 (9%) Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRTGESRHKTRGDKIA 455 S+ S SS S E + S KE + +R+K + S H E + K++ K+ Sbjct: 260 SSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLH 319 Query: 456 QKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGV--SHTPISKESRT-SHKSGRSL 512 ++ SS SH NR+ KEK P +H S + SH+ K+SRT H + Sbjct: 320 EELSS----SHH-NREKAKEK----PRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRG 370 Query: 513 WTTSSGSSKGLGR 525 GSS+ GR Sbjct: 371 SERKEGSSRSHGR 383 Score = 35.0 bits (79), Expect = 0.19 Identities = 39/174 (22%), Positives = 69/174 (39%), Gaps = 27/174 (15%) Query: 350 KSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLSGQHG 409 K +H SS+S S S S S TS +++E++ + ++ K+ SG + Sbjct: 251 KHKKHKSSSSSSSSSSSSSSTE------TSESSSESESNNKEKKIQRKKRKKNKCSGHNN 304 Query: 410 --------------RERTQASAEGCKEGRER-----REKDRALGRSSHRRRTGESR-HKT 449 E +S ++ +E+ E R + SH +SR HK Sbjct: 305 SDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKH 364 Query: 450 RGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESR 503 +K + SS SH ++ + +PGS + R++ K P ++SR Sbjct: 365 SPEKRGSERKEGSSRSHGREERSRRSRS-RSPGSYKQRETRKRAQRNPGEEQSR 417 Score = 33.9 bits (76), Expect = 0.43 Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 2/106 (1%) Query: 396 STRQSKSSLSGQHGRERTQASAEGCKEGRERRE-KDRALGRSSHRRRTGESRHKTRGDKI 454 S SK S S + RT + K G ER+E R+ GR RR+ + + Sbjct: 344 SREDSKWSHSDSDKKSRTHKHSPE-KRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRE 402 Query: 455 AQKSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISK 500 +K + R+ ++ R+D + G + H G +HT +++ Sbjct: 403 TRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHTKVTQ 448 >gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens] Length = 221 Score = 42.0 bits (97), Expect = 0.002 Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 3/88 (3%) Query: 424 RERREKDRALGRSSHRRRTGESRHKTRGDKIAQKSSSRSSFSHRANRDDKKEKGCGNPGS 483 R RR + R+ RS R R+ SR K+R +S SRS+ R+ R K + + Sbjct: 124 RRRRSRSRSRSRSRSRSRSRYSRSKSRS---RTRSRSRSTSKSRSARRSKSKSSSVSRSR 180 Query: 484 SRHRDSHKGVSHTPISKESRTSHKSGRS 511 SR R + S P+SK S +S Sbjct: 181 SRSRSRSRSRSPPPVSKRESKSRSRSKS 208 >gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 41.6 bits (96), Expect = 0.002 Identities = 54/285 (18%), Positives = 102/285 (35%), Gaps = 7/285 (2%) Query: 263 STELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGG 322 S E +E + + AG+ T TV+ A S S G + ++ + Sbjct: 957 SAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016 Query: 323 NKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTA 382 + T++ +T V AG+ + S + + S EGS + ++ + TA Sbjct: 1017 STTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTA 1076 Query: 383 AEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRT 442 + AD++ VST S ++ + G E T G K E A S+ T Sbjct: 1077 STADLETTT---VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133 Query: 443 GESRHKTRGDKIAQ--KSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISK 500 + T G ++ + S ++ + G+ ++ + + + + Sbjct: 1134 --TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS 1191 Query: 501 ESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTKVVGTP 545 E+ T+ +G T S+ S+ +S A T TP Sbjct: 1192 ETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1236 Score = 40.4 bits (93), Expect = 0.005 Identities = 41/180 (22%), Positives = 76/180 (42%), Gaps = 17/180 (9%) Query: 252 TNVLNASIPKTSTELAEE---PATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQV 308 T ++ AS T++ E P+ G + + + + T + AG+ + +++ G Sbjct: 27 TILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTT 86 Query: 309 SAAIAGAATI--DAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREG 366 +A++AG+ T AG +++ GT +T V+ G+ ++ SS + S G Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGT-----ETTMVSAMGSETTTNSTTSSETTVTSTAG 141 Query: 367 SVSLAIAGVVLTSRTAAEADMDAAAG-------PPVSTRQSKSSLSGQHGRERTQASAEG 419 S + ++ V + TA AD + A V T S++ G E T S G Sbjct: 142 SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAG 201 Score = 36.6 bits (83), Expect = 0.067 Identities = 32/149 (21%), Positives = 55/149 (36%), Gaps = 5/149 (3%) Query: 271 ATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALA 330 +T G + + + T + G + + + + GA T A Sbjct: 527 STEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586 Query: 331 GTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAA 390 TA +T V+ A + ++ S + S S GS + + TS A + + Sbjct: 587 STAGS--ETTTVSTADSENTTASTADSETTSASTTGSETTTAS---TTSSETTTASTEGS 641 Query: 391 AGPPVSTRQSKSSLSGQHGRERTQASAEG 419 VST S++++ G ERT S EG Sbjct: 642 ETTTVSTTDSETTMVSTTGSERTITSTEG 670 Score = 36.6 bits (83), Expect = 0.067 Identities = 45/193 (23%), Positives = 78/193 (40%), Gaps = 12/193 (6%) Query: 234 TSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVA 293 TSA+ G E + ASI + T +A +T G + + A++ T Sbjct: 753 TSASTTGSETTTASTTSSETTM-ASIMGSETTMA---STIGSETTKVSTASSKMTTVFTE 808 Query: 294 GALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGA----AG 349 + + A+ +A + + AG+ TI A G+ T++ +T + G+ A Sbjct: 809 NSETTIASTTASETTTVSTAGSETIPAS-TAGSETTTTTSTEGSETTTASTEGSETTTAS 867 Query: 350 KSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPP---VSTRQSKSSLSG 406 S ++A+ S + S + TS +E + G VST S+++ + Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927 Query: 407 QHGRERTQASAEG 419 G E T AS EG Sbjct: 928 TEGSETTTASTEG 940 Score = 36.6 bits (83), Expect = 0.067 Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 21/130 (16%) Query: 262 TSTELAEEP--ATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGA--AT 317 TSTE +E +T G + A+ A + T + AG+ + A+ S +A G+ +T Sbjct: 1176 TSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETST 1235 Query: 318 IDAGGNKGNMA--------LAGTASMAPNSTKVA---------VAGAAGKSSEHVSSASM 360 + G++ N A +A TAS+ P +T + A A +S VSS + Sbjct: 1236 PSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTF 1295 Query: 361 SLSREGSVSL 370 L++ VS+ Sbjct: 1296 VLTKATDVSI 1305 Score = 32.7 bits (73), Expect = 0.97 Identities = 34/156 (21%), Positives = 61/156 (39%), Gaps = 12/156 (7%) Query: 272 TGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAG 331 T + AA+ + T AG+ ++ + + + + AG+ T A Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218 Query: 332 TA--------SMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAA 383 TA +M +TKV+ AG+ S S + + + + + A T+ TA+ Sbjct: 219 TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT-TAS 277 Query: 384 EADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEG 419 + A ST S+ +++ G E T AS G Sbjct: 278 TTGFETTA---ASTTGSEPTMASTMGSETTMASTIG 310 Score = 32.3 bits (72), Expect = 1.3 Identities = 43/198 (21%), Positives = 76/198 (38%), Gaps = 21/198 (10%) Query: 227 VSEVCGATSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAG 286 VS T+ A G + F T V + T A + G + + + Sbjct: 1126 VSTTSSETTTASTTGSEMTTVF---TTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE 1182 Query: 287 AATGTVAGALSVAAANSAPGQVSAAIAGAATIDA--GGNKGNMAL-----AGTASMAPNS 339 T + AG+ + A+ + +A+ AG+ T A G++ N A T S A + Sbjct: 1183 TTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1242 Query: 340 TKVA-VAGA----AGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADM------D 388 T A + G+ A +S ++ S++ S +VS+ +G S T + D Sbjct: 1243 TNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATD 1302 Query: 389 AAAGPPVSTRQSKSSLSG 406 + P +T S + +G Sbjct: 1303 VSIQPITNTPMSGTRTTG 1320 >gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 41.6 bits (96), Expect = 0.002 Identities = 54/285 (18%), Positives = 102/285 (35%), Gaps = 7/285 (2%) Query: 263 STELAEEPATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGG 322 S E +E + + AG+ T TV+ A S S G + ++ + Sbjct: 957 SAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016 Query: 323 NKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTA 382 + T++ +T V AG+ + S + + S EGS + ++ + TA Sbjct: 1017 STTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTA 1076 Query: 383 AEADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEGCKEGRERREKDRALGRSSHRRRT 442 + AD++ VST S ++ + G E T G K E A S+ T Sbjct: 1077 STADLETTT---VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133 Query: 443 GESRHKTRGDKIAQ--KSSSRSSFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISK 500 + T G ++ + S ++ + G+ ++ + + + + Sbjct: 1134 --TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS 1191 Query: 501 ESRTSHKSGRSLWTTSSGSSKGLGRVSSFLRNVRANLTTKVVGTP 545 E+ T+ +G T S+ S+ +S A T TP Sbjct: 1192 ETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1236 Score = 40.4 bits (93), Expect = 0.005 Identities = 41/180 (22%), Positives = 76/180 (42%), Gaps = 17/180 (9%) Query: 252 TNVLNASIPKTSTELAEE---PATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQV 308 T ++ AS T++ E P+ G + + + + T + AG+ + +++ G Sbjct: 27 TILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTT 86 Query: 309 SAAIAGAATI--DAGGNKGNMALAGTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREG 366 +A++AG+ T AG +++ GT +T V+ G+ ++ SS + S G Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGT-----ETTMVSAMGSETTTNSTTSSETTVTSTAG 141 Query: 367 SVSLAIAGVVLTSRTAAEADMDAAAG-------PPVSTRQSKSSLSGQHGRERTQASAEG 419 S + ++ V + TA AD + A V T S++ G E T S G Sbjct: 142 SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAG 201 Score = 36.6 bits (83), Expect = 0.067 Identities = 32/149 (21%), Positives = 55/149 (36%), Gaps = 5/149 (3%) Query: 271 ATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALA 330 +T G + + + T + G + + + + GA T A Sbjct: 527 STEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586 Query: 331 GTASMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAA 390 TA +T V+ A + ++ S + S S GS + + TS A + + Sbjct: 587 STAGS--ETTTVSTADSENTTASTADSETTSASTTGSETTTAS---TTSSETTTASTEGS 641 Query: 391 AGPPVSTRQSKSSLSGQHGRERTQASAEG 419 VST S++++ G ERT S EG Sbjct: 642 ETTTVSTTDSETTMVSTTGSERTITSTEG 670 Score = 36.6 bits (83), Expect = 0.067 Identities = 45/193 (23%), Positives = 78/193 (40%), Gaps = 12/193 (6%) Query: 234 TSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAGAATGTVA 293 TSA+ G E + ASI + T +A +T G + + A++ T Sbjct: 753 TSASTTGSETTTASTTSSETTM-ASIMGSETTMA---STIGSETTKVSTASSKMTTVFTE 808 Query: 294 GALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGA----AG 349 + + A+ +A + + AG+ TI A G+ T++ +T + G+ A Sbjct: 809 NSETTIASTTASETTTVSTAGSETIPAS-TAGSETTTTTSTEGSETTTASTEGSETTTAS 867 Query: 350 KSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPP---VSTRQSKSSLSG 406 S ++A+ S + S + TS +E + G VST S+++ + Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927 Query: 407 QHGRERTQASAEG 419 G E T AS EG Sbjct: 928 TEGSETTTASTEG 940 Score = 36.6 bits (83), Expect = 0.067 Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 21/130 (16%) Query: 262 TSTELAEEP--ATGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGA--AT 317 TSTE +E +T G + A+ A + T + AG+ + A+ S +A G+ +T Sbjct: 1176 TSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETST 1235 Query: 318 IDAGGNKGNMA--------LAGTASMAPNSTKVA---------VAGAAGKSSEHVSSASM 360 + G++ N A +A TAS+ P +T + A A +S VSS + Sbjct: 1236 PSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTF 1295 Query: 361 SLSREGSVSL 370 L++ VS+ Sbjct: 1296 VLTKATDVSI 1305 Score = 32.7 bits (73), Expect = 0.97 Identities = 34/156 (21%), Positives = 61/156 (39%), Gaps = 12/156 (7%) Query: 272 TGGIKEAAAAGAAAGAATGTVAGALSVAAANSAPGQVSAAIAGAATIDAGGNKGNMALAG 331 T + AA+ + T AG+ ++ + + + + AG+ T A Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218 Query: 332 TA--------SMAPNSTKVAVAGAAGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAA 383 TA +M +TKV+ AG+ S S + + + + + A T+ TA+ Sbjct: 219 TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT-TAS 277 Query: 384 EADMDAAAGPPVSTRQSKSSLSGQHGRERTQASAEG 419 + A ST S+ +++ G E T AS G Sbjct: 278 TTGFETTA---ASTTGSEPTMASTMGSETTMASTIG 310 Score = 32.3 bits (72), Expect = 1.3 Identities = 43/198 (21%), Positives = 76/198 (38%), Gaps = 21/198 (10%) Query: 227 VSEVCGATSAAYAGGEGLQNDFNKPTNVLNASIPKTSTELAEEPATGGIKEAAAAGAAAG 286 VS T+ A G + F T V + T A + G + + + Sbjct: 1126 VSTTSSETTTASTTGSEMTTVF---TTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE 1182 Query: 287 AATGTVAGALSVAAANSAPGQVSAAIAGAATIDA--GGNKGNMAL-----AGTASMAPNS 339 T + AG+ + A+ + +A+ AG+ T A G++ N A T S A + Sbjct: 1183 TTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1242 Query: 340 TKVA-VAGA----AGKSSEHVSSASMSLSREGSVSLAIAGVVLTSRTAAEADM------D 388 T A + G+ A +S ++ S++ S +VS+ +G S T + D Sbjct: 1243 TNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATD 1302 Query: 389 AAAGPPVSTRQSKSSLSG 406 + P +T S + +G Sbjct: 1303 VSIQPITNTPMSGTRTTG 1320 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.126 0.353 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,776,148 Number of Sequences: 37866 Number of extensions: 888142 Number of successful extensions: 6213 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 148 Number of HSP's successfully gapped in prelim test: 333 Number of HSP's that attempted gapping in prelim test: 4164 Number of HSP's gapped (non-prelim): 1617 length of query: 594 length of database: 18,247,518 effective HSP length: 108 effective length of query: 486 effective length of database: 14,157,990 effective search space: 6880783140 effective search space used: 6880783140 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.