Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 239508698

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239508698 PREDICTED: similar to mucin [Homo sapiens]
         (265 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239508698 PREDICTED: similar to mucin [Homo sapiens]               534   e-152
gi|239754474 PREDICTED: similar to mucin [Homo sapiens]               498   e-141
gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo ...   409   e-114
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]            67   2e-11
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             59   3e-09
gi|30795231 brain abundant, membrane attached signal protein 1 [...    57   2e-08
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]                56   3e-08
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    55   5e-08
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        55   6e-08
gi|153070260 myristoylated alanine-rich protein kinase C substra...    55   8e-08
gi|38788274 bromodomain PHD finger transcription factor isoform ...    55   8e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              54   1e-07
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom...    54   2e-07
gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ...    52   5e-07
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    51   9e-07
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    51   1e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         51   1e-06
gi|71274172 ankyrin repeat domain 56 [Homo sapiens]                    51   1e-06
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     50   2e-06
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     50   2e-06
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]       50   2e-06
gi|239750916 PREDICTED: similar to hCG1803335 [Homo sapiens]           50   2e-06
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         50   2e-06
gi|50962882 G patch domain containing 8 [Homo sapiens]                 50   3e-06
gi|60097902 filaggrin [Homo sapiens]                                   49   3e-06
gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo ...    49   3e-06
gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo ...    49   3e-06
gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]            49   3e-06
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    49   3e-06
gi|38788260 bromodomain PHD finger transcription factor isoform ...    49   5e-06

>gi|239508698 PREDICTED: similar to mucin [Homo sapiens]
          Length = 265

 Score =  534 bits (1375), Expect = e-152
 Identities = 265/265 (100%), Positives = 265/265 (100%)

Query: 1   MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
           MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD
Sbjct: 1   MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60

Query: 61  QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ 120
           QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ
Sbjct: 61  QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ 120

Query: 121 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS 180
           RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS
Sbjct: 121 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS 180

Query: 181 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240
           PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR
Sbjct: 181 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240

Query: 241 AQDREEEAAAAPAPTSSGHRTEKRK 265
           AQDREEEAAAAPAPTSSGHRTEKRK
Sbjct: 241 AQDREEEAAAAPAPTSSGHRTEKRK 265


>gi|239754474 PREDICTED: similar to mucin [Homo sapiens]
          Length = 417

 Score =  498 bits (1281), Expect = e-141
 Identities = 250/265 (94%), Positives = 251/265 (94%)

Query: 1   MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
           MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD
Sbjct: 1   MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60

Query: 61  QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ 120
           QQGAQDREEEAAAAPAADQQRAQDREEEAAAAP PTSSGHRTEKRK  Q QC+PAGGTGQ
Sbjct: 61  QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ 120

Query: 121 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS 180
           RRGS SSPSADQQ AQDREEEAAAAP PTSRGHRTEKRK QQPQRRPA GTGQRRGS SS
Sbjct: 121 RRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSS 180

Query: 181 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240
           PSADQQGAQDREEEAAAAP PTSRGHRTEKRK QQPQCRPA GTGQRRGSRSSPSADQQR
Sbjct: 181 PSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQR 240

Query: 241 AQDREEEAAAAPAPTSSGHRTEKRK 265
           AQDREEEAAAAPAPTS GHRTEKRK
Sbjct: 241 AQDREEEAAAAPAPTSRGHRTEKRK 265



 Score =  386 bits (992), Expect = e-108
 Identities = 206/267 (77%), Positives = 210/267 (78%), Gaps = 35/267 (13%)

Query: 34  RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAP------------------ 75
           R + Q QCQPAGGTGQRRGS SSPSADQQ AQDREEEAAAAP                  
Sbjct: 105 RKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQ 164

Query: 76  -----------------AADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGT 118
                            +ADQQ AQDREEEAAAAPAPTS GHRTEKRKPQQPQCRPAGGT
Sbjct: 165 RRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGT 224

Query: 119 GQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSR 178
           GQRRGS SSPSADQQ AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPA GTGQRRGS 
Sbjct: 225 GQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSG 284

Query: 179 SSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQ 238
            SPSADQQGAQDREEEAAAAP PTS GHRTEKRKR Q QC+PA GTGQRRGS  S SA+Q
Sbjct: 285 YSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQ 344

Query: 239 QRAQDREEEAAAAPAPTSSGHRTEKRK 265
           Q AQDREEEAAAAP PTSSGHRTEKRK
Sbjct: 345 QGAQDREEEAAAAPVPTSSGHRTEKRK 371



 Score =  354 bits (909), Expect = 4e-98
 Identities = 192/249 (77%), Positives = 196/249 (78%), Gaps = 35/249 (14%)

Query: 34  RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA----------------- 76
           R +QQPQ +PAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA                 
Sbjct: 158 RKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 217

Query: 77  ------------------ADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGT 118
                             ADQQRAQDREEEAAAAPAPTS GHRTEKRKPQQPQ RPAGGT
Sbjct: 218 CRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGT 277

Query: 119 GQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSR 178
           GQRRGSG SPSADQQGAQDREEEAAAAPAPTS GHRTEKRK  Q Q +PA GTGQRRGS 
Sbjct: 278 GQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSG 337

Query: 179 SSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQ 238
            S SA+QQGAQDREEEAAAAPVPTS GHRTEKRK QQPQ RPAAGTGQRRGS SSPSADQ
Sbjct: 338 CSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQ 397

Query: 239 QRAQDREEE 247
           QRAQDREEE
Sbjct: 398 QRAQDREEE 406



 Score =  173 bits (439), Expect = 1e-43
 Identities = 101/173 (58%), Positives = 109/173 (63%), Gaps = 39/173 (22%)

Query: 4   RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG 63
           +Q+ QD         +   +    EK KP +PQ+    +PAGGTGQRRGSG SPSADQQG
Sbjct: 238 QQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQR----RPAGGTGQRRGSGYSPSADQQG 293

Query: 64  AQDREEEAAAAPA-----------------------------------ADQQRAQDREEE 88
           AQDREEEAAAAPA                                   A+QQ AQDREEE
Sbjct: 294 AQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEE 353

Query: 89  AAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEE 141
           AAAAP PTSSGHRTEKRKPQQPQ RPA GTGQRRGSGSSPSADQQ AQDREEE
Sbjct: 354 AAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEE 406


>gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo
           sapiens]
          Length = 306

 Score =  409 bits (1051), Expect = e-114
 Identities = 222/293 (75%), Positives = 224/293 (76%), Gaps = 53/293 (18%)

Query: 1   MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
           MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD
Sbjct: 1   MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60

Query: 61  QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ 120
           QQGA                  QDREEEAAAAPAPTS GHRTEKRKPQQPQ RPAGGTGQ
Sbjct: 61  QQGA------------------QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQ 102

Query: 121 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS 180
           RRGS SS SADQQGAQDREEEAAAAPAPTS GHRTEKRKPQQPQ RPAAGTGQRRGS  S
Sbjct: 103 RRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCS 162

Query: 181 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQC------------------RPAA 222
           PSADQQ AQDREEEA AAPVPTS GHRTEKRKR Q QC                  +PA 
Sbjct: 163 PSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAG 222

Query: 223 GTGQRRGSRSSPSADQQRAQDREEEA-----------------AAAPAPTSSG 258
           GTGQRRGSRSSPSADQQRAQDREEEA                 AAAP PT+ G
Sbjct: 223 GTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGG 275



 Score =  302 bits (774), Expect = 2e-82
 Identities = 155/191 (81%), Positives = 159/191 (83%), Gaps = 4/191 (2%)

Query: 79  QQRAQDREEEAAAAPAPTSSGHRTEKRKP----QQPQCRPAGGTGQRRGSGSSPSADQQG 134
           +Q+ QD         +        EK KP    QQPQC+PAGGTGQRRGSGSSPSADQQG
Sbjct: 4   RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG 63

Query: 135 AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEE 194
           AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPA GTGQRRGSRSS SADQQGAQDREEE
Sbjct: 64  AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEE 123

Query: 195 AAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAP 254
           AAAAP PTS GHRTEKRK QQPQCRPAAGTGQRRGS  SPSADQQRAQDREEEA AAP P
Sbjct: 124 AAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVP 183

Query: 255 TSSGHRTEKRK 265
           TSSGHRTEKRK
Sbjct: 184 TSSGHRTEKRK 194



 Score =  188 bits (477), Expect = 5e-48
 Identities = 100/139 (71%), Positives = 109/139 (78%), Gaps = 1/139 (0%)

Query: 128 PSADQQGAQDREEEAAAAPAPTSRGHRTEKRKP-QQPQRRPAAGTGQRRGSRSSPSADQQ 186
           P   +Q  + R+   ++         +T+  +P QQPQ +PA GTGQRRGS SSPSADQQ
Sbjct: 3   PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62

Query: 187 GAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREE 246
           GAQDREEEAAAAP PTSRGHRTEKRK QQPQ RPA GTGQRRGSRSS SADQQ AQDREE
Sbjct: 63  GAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREE 122

Query: 247 EAAAAPAPTSSGHRTEKRK 265
           EAAAAPAPTSSGHRTEKRK
Sbjct: 123 EAAAAPAPTSSGHRTEKRK 141



 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 37/112 (33%), Positives = 45/112 (40%), Gaps = 40/112 (35%)

Query: 13  RKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAA 72
           R  R S   DQ    ++ +      QPQ +PAGGTGQRRG+ ++P     G   R     
Sbjct: 228 RGSRSSPSADQQRAQDREEEAA---QPQRRPAGGTGQRRGTAAAPVPTTGGTGQR----- 279

Query: 73  AAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGS 124
                            AAAPAPTS+                  GTGQRRGS
Sbjct: 280 --------------RGTAAAPAPTST------------------GTGQRRGS 299


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 66/265 (24%), Positives = 111/265 (41%), Gaps = 24/265 (9%)

Query: 13  RKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDRE--EE 70
           +KLR   +       ++       ++P  +  GG G +   G +P   + G + R   ++
Sbjct: 272 KKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQK 331

Query: 71  AAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPS- 129
           A  A AA  +R    +++AA     +    R   +KP++ +   AG   + RG G     
Sbjct: 332 ATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGA--KSRGGGDKKGL 389

Query: 130 --ADQQGA-------QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS 180
             A ++G        Q+    A  APA   RG  ++K + + P+   + G   R G    
Sbjct: 390 REAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKK 449

Query: 181 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240
           P    Q A+ +  EA A     SRG + + R++       AAGT  R G   S S     
Sbjct: 450 PRRRGQKARQKAAEAGAE----SRGDKKQGRQKAS-----AAGTKSRGGGLKSHSGKNLW 500

Query: 241 AQDREEEAAAAPAPTSSGHRTEKRK 265
            + ++ EAA   A T++G ++  RK
Sbjct: 501 RRGQKAEAAGEKA-TAAGAKSRGRK 524



 Score = 61.2 bits (147), Expect = 9e-10
 Identities = 60/216 (27%), Positives = 87/216 (40%), Gaps = 23/216 (10%)

Query: 46  GTGQRRGSGSSPSADQQGAQDREEEAAAAPAAD---QQRAQDREEEAAAAPAPTSSGHRT 102
           G   RR   S+  A  +G  D++    A    D   + R Q+    A  APA    G  +
Sbjct: 365 GKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGS 424

Query: 103 EKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ 162
           +K + + P+   + G   R G G  P    Q A+ +  EA A     SRG + + R    
Sbjct: 425 KKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGA----ESRGDKKQGR---- 476

Query: 163 PQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAA 222
            Q+  AAGT  R G   S S      + ++ EAA     T+ G ++  RK+ + Q    A
Sbjct: 477 -QKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKA-TAAGAKSRGRKQPRRQKPAVA 534

Query: 223 GTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSG 258
           G   R G   S          R+ + A A   TS G
Sbjct: 535 GAKSRVGGSKS----------RQRQKAVAAGATSHG 560



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 51/190 (26%), Positives = 84/190 (44%), Gaps = 28/190 (14%)

Query: 63  GAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRR 122
           G + R+    AA A   +     E++AAAA   +  G   + R+  Q     A  TG ++
Sbjct: 82  GKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRGRKPRRRGQK----AAATGSKK 137

Query: 123 GSGSSPSADQQGAQDR---EEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTG------- 172
               +  +   G+++R    ++AAAA    S+G        ++PQ+  AAG         
Sbjct: 138 PRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGG-------EKPQKAAAAGAKSRSGKKP 190

Query: 173 QRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRS 232
           +RRG++S    D++G Q      A +    +RG R +K +R +P    A G   RRG   
Sbjct: 191 RRRGAKSRGDEDKKGRQ----REAKSRFGKTRGGRRKKHRRPKP---AAGGAKSRRGGGK 243

Query: 233 SPSADQQRAQ 242
            P   ++R Q
Sbjct: 244 KPQKQRRRGQ 253



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 61/221 (27%), Positives = 102/221 (46%), Gaps = 36/221 (16%)

Query: 16  RESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEA--AA 73
           + ++ G + L     KP R  Q+     A  TG ++    +  +   G+++R   A  AA
Sbjct: 107 KAAAAGTKSLGGRGRKPRRRGQK-----AAATGSKKPRWRAQKSAAAGSKNRGAGAQKAA 161

Query: 74  APAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQ 133
           A A  + +  ++ ++AAAA A + SG     +KP            +RRG+ S    D++
Sbjct: 162 AAAGVKSQGGEKPQKAAAAGAKSRSG-----KKP------------RRRGAKSRGDEDKK 204

Query: 134 GAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQ-RRGSRSSPSADQQGAQDRE 192
           G   R+ EA +    T  G R + R+P     +PAAG  + RRG    P   ++  Q + 
Sbjct: 205 G---RQREAKSRFGKTRGGRRKKHRRP-----KPAAGGAKSRRGGGKKPQKQRRRGQ-KA 255

Query: 193 EEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSS 233
                + V  SRG   +K+ R+Q Q    AG  +RRG+ ++
Sbjct: 256 ATGGKSRVGKSRG-GGDKKLRRQGQNAALAG-AKRRGAATA 294



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 73/308 (23%), Positives = 114/308 (37%), Gaps = 58/308 (18%)

Query: 2   KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTG-------QRRGSG 54
           KPR + Q +     +    G Q          +  ++PQ   A G         +RRG+ 
Sbjct: 137 KPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAGAKSRSGKKPRRRGAK 196

Query: 55  SSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEK---RKPQQPQ 111
           S    D++G Q RE ++        +R + R       P P + G ++ +   +KPQ+ +
Sbjct: 197 SRGDEDKKGRQ-REAKSRFGKTRGGRRKKHRR------PKPAAGGAKSRRGGGKKPQKQR 249

Query: 112 CR----PAGG---TGQRRGSG------SSPSADQQGAQDR-EEEAAAAPAPTSRGHRTEK 157
            R      GG    G+ RG G         +A   GA+ R    A   PA   RG R  K
Sbjct: 250 RRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGPK 309

Query: 158 ----------RKPQQPQRR-----PAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPT 202
                     R  ++P+RR      AA  G +RG      A   G + R+++        
Sbjct: 310 SLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQ-------R 362

Query: 203 SRGHRTEKRKRQQPQCRPAAG---TGQRRGSRSSPSADQQRAQDREEEAAAAPA--PTSS 257
            RG +  ++K      +   G    G R   R      + R Q+    A  APA  P   
Sbjct: 363 RRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGG 422

Query: 258 GHRTEKRK 265
           G +  +R+
Sbjct: 423 GSKKPRRR 430



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 72/329 (21%), Positives = 122/329 (37%), Gaps = 75/329 (22%)

Query: 2   KPRQKEQDTRLRKLRESSE--GDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSA 59
           KPR++ Q  R +     +E  GD+    +K      + +       G G +  SG +   
Sbjct: 449 KPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSR-------GGGLKSHSGKNLWR 501

Query: 60  DQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQ----------- 108
             Q A+   E+A AA A  + R Q R ++ A A A +  G    +++ +           
Sbjct: 502 RGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGG 561

Query: 109 --QPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR 166
               Q R  GG   R+   ++ +A  +G  D++     A A  ++    +  K  +  R+
Sbjct: 562 GGNKQSRGGGGNKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGK--KAWRQ 619

Query: 167 PAAGTGQ-------RRGSRSSPSADQQ-----------GAQDR---------EEEAAAAP 199
            AAGTG        RRG + + +A++            G Q R         E  AAAA 
Sbjct: 620 KAAGTGAKSRKKPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAV 679

Query: 200 VPTSRGHRTEKRKR----------------------QQPQCRPAAGTG--QRRGSRSSPS 235
              +   +  +R+R                      ++P+   + G G  + RGS  + S
Sbjct: 680 GQEAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKS 739

Query: 236 ADQQRAQDREEEAAAAPAPTSSGHRTEKR 264
                A+ R  + AAA      G    +R
Sbjct: 740 RGSGGAKSRSGKKAAASKSHGGGGAKRRR 768



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 65/268 (24%), Positives = 102/268 (38%), Gaps = 46/268 (17%)

Query: 37  QQPQCQPAGGTGQRRGSGSSPSADQQGAQDRE--EEAAAAPAADQQRAQDREEEAAAAPA 94
           +Q Q   A G     G G+  S    G + R+  + AAAA        Q   ++AAA   
Sbjct: 546 RQRQKAVAAGATSHGGGGNKQSRGGGGNKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVT 605

Query: 95  PTSSGHRTEKRKPQQPQCRPAGGTGQ-------RRGSGSSPSADQQ-----------GAQ 136
            + SG   +K   Q+     A GTG        RRG   + +A++            G Q
Sbjct: 606 KSRSGDGGKKAWRQK-----AAGTGAKSRKKPWRRGQKDAAAAEKAWATGATSRGSGGKQ 660

Query: 137 DREEEAAAAPAPTSR----GHRTEKRKPQQPQRRPAAGTG-----------QRRGSRSSP 181
            R ++ AAA + +S     G   E RK  + +R  + G G           QRRG +   
Sbjct: 661 PRWQKPAAAGSESSAAAAVGQEAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRL 720

Query: 182 SADQQGAQDREEEAAAAPVPTSRGHRTEK-RKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240
              + G   +   +  A    S G ++   +K    +     G  +RRG  +   + ++ 
Sbjct: 721 GKSRGGGGAKSRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKA 780

Query: 241 AQDREEEAAAA-----PAPTSSGHRTEK 263
                ++AAAA     P   S G R +K
Sbjct: 781 VTAGGQKAAAAGGKKPPRVKSRGGRGQK 808



 Score = 37.4 bits (85), Expect = 0.014
 Identities = 41/172 (23%), Positives = 74/172 (43%), Gaps = 22/172 (12%)

Query: 111 QCRPAGGTGQRRGSGSSPSAD--QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPA 168
           QC  A G   R G G+   A   +   +   E AA A +  + G +      ++ +R+ A
Sbjct: 8   QCNQAAG---RAGPGAPLGAALARTPVELAAESAAPALSAAAAGVKILGSGDKKLRRQKA 64

Query: 169 AGTGQR---RGSRSS-----------PSADQQGAQDR---EEEAAAAPVPTSRGHRTEKR 211
           A  G++   RG + +            +A   GA++R   E++AAAA   +  G   + R
Sbjct: 65  AAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRGRKPR 124

Query: 212 KRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEK 263
           +R Q      +   + R  +S+ +  + R    ++ AAAA   +  G + +K
Sbjct: 125 RRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQK 176



 Score = 31.6 bits (70), Expect = 0.75
 Identities = 43/176 (24%), Positives = 64/176 (36%), Gaps = 50/176 (28%)

Query: 4   RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQP------AGGTGQRRGSGSSP 57
           ++ E   + R+ R  S GD          + P Q+   +P       GG  + RGSG + 
Sbjct: 681 QEAEARKKPRRRRAKSRGDGG--QNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAK 738

Query: 58  SADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGG 117
           S    GA+ R  + AAA                      S  H               GG
Sbjct: 739 SRGSGGAKSRSGKKAAA----------------------SKSHG-------------GGG 763

Query: 118 TGQRRGSGSSPSADQQGAQDREEEAAAA-----PAPTSRGHRTEKRKP--QQPQRR 166
             +RRG G+   + ++      ++AAAA     P   SRG R +K     ++P RR
Sbjct: 764 AKRRRGGGAKSRSGEKAVTAGGQKAAAAGGKKPPRVKSRGGRGQKAAAGGKKPLRR 819


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 70/286 (24%), Positives = 108/286 (37%), Gaps = 45/286 (15%)

Query: 4   RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSS--PSADQ 61
           R +      RK R  S   +    EK K    +++P  +  G    R  SGSS  PS   
Sbjct: 211 RDRSDSGSRRKRRHRSRSSKCKRKEKNKE---KKRPHTESPGRRSHRHSSGSSHSPSLSS 267

Query: 62  QGAQDREEEAAAAPAADQQRAQDREEEAAA-APAPTS-SGHRTEKRKPQQPQCRPAGGTG 119
             +  R     +    D+ R    +  + + +P+P+  SG  + +R     Q   +G  G
Sbjct: 268 HYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQ--RSGAHG 325

Query: 120 QRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRS 179
            R GS  SP         R  + AAA APT      E   P+      +A + Q RG R+
Sbjct: 326 GRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPR------SAPSSQGRGGRA 379

Query: 180 SPSADQQGAQDREEEAA--AAPVPTSRGHRTEKRKRQQP--------------------Q 217
           +  A ++  + R    +  +A  P  RG     R+R +P                     
Sbjct: 380 AGGAGRRRRRRRRRRRSRSSASAPRRRG-----RRRPRPAPPRGSSRSLSRARSSSDSGS 434

Query: 218 CRPAAGTGQRRGSRSSPSADQQRAQD---REEEAAAAPAPTSSGHR 260
            R A G G   GS        +RA++   R   A+ +P+P + G R
Sbjct: 435 GRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRR 480



 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 61/238 (25%), Positives = 89/238 (37%), Gaps = 37/238 (15%)

Query: 26  ENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDR 85
           E  KT   R        P+GG+G      +  S  + GA      +A +P         R
Sbjct: 285 EGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPR 344

Query: 86  EEEAAAAPAPTSSGHRTEKRKPQQPQC------RPAGGTGQRRGSGSSPSADQQGAQDRE 139
             + AAA APT      E   P+          R AGG G+RR          +  + R 
Sbjct: 345 VRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRR----------RRRRRRR 394

Query: 140 EEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAP 199
              ++A AP  RG R  +  P +   R  +     R   SS S   +GA          P
Sbjct: 395 RSRSSASAPRRRGRRRPRPAPPRGSSRSLS-----RARSSSDSGSGRGA------PGPGP 443

Query: 200 VPTS-RGH--RTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAP 254
            P S RGH    ++ K + P+ RPA+       +  SP A  +R     + ++ +P P
Sbjct: 444 EPGSERGHGGHGKRAKERPPRARPAS-------TSPSPGAHGRRGGPEGKSSSRSPGP 494


>gi|30795231 brain abundant, membrane attached signal protein 1
           [Homo sapiens]
          Length = 227

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 48/209 (22%), Positives = 85/209 (40%), Gaps = 34/209 (16%)

Query: 58  SADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGG 117
           + + + A++++++A  A   ++   ++ E +AAA PA    G    K KP Q        
Sbjct: 13  NVNDEKAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEG----KEKPDQ-------- 60

Query: 118 TGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGS 177
                G       ++  A  +EE   A P  T      +   P+ P++  AA        
Sbjct: 61  --DAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAA-------- 110

Query: 178 RSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCR----PAAGTGQRRGSRSS 233
              P     G   +  EAAAAP  ++     E+  +++ + +    PAA   Q   S  +
Sbjct: 111 ---PGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGA 167

Query: 234 PSAD-----QQRAQDREEEAAAAPAPTSS 257
           P++D      + A   +E  AA  AP+S+
Sbjct: 168 PASDSKPGSSEAAPSSKETPAATEAPSST 196



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 50/197 (25%), Positives = 81/197 (41%), Gaps = 29/197 (14%)

Query: 17  ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG-AQDREEEAAAAP 75
           ++ E D+  E   T+     ++ + Q A    + +     P  D +G A+++E E  AA 
Sbjct: 18  KAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAA 77

Query: 76  AADQQRAQDREEEAAAAPAPTSSGHRTEK----RKPQQPQCRPAGGTGQRRGSGSSPSAD 131
           A         +EEA  A    + G    K    + P+Q Q  P    G     G +P A 
Sbjct: 78  A---------KEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAG-----GEAPKAA 123

Query: 132 QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSAD-----QQ 186
           +  A   E  A AA    S+    E+ +P++ +  PAA   Q   S  +P++D      +
Sbjct: 124 EAAAAPAESAAPAAGEEPSK----EEGEPKKTE-APAAPAAQETKSDGAPASDSKPGSSE 178

Query: 187 GAQDREEEAAAAPVPTS 203
            A   +E  AA   P+S
Sbjct: 179 AAPSSKETPAATEAPSS 195


>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
          Length = 2303

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 61/250 (24%), Positives = 90/250 (36%), Gaps = 32/250 (12%)

Query: 36   QQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAP 95
            Q  P+ QP G  G++R +G  P++ +Q    R +   A  +A+Q R   +       P  
Sbjct: 1412 QGPPRDQPGGPAGRQRPTGR-PTSARQAMGHRHKAGGAGRSAEQSRGAGKNRAGLELPL- 1469

Query: 96   TSSGHRTEKRKPQQPQCRPAGGTGQRRGSG-------SSPSADQ----QGAQDREEEAAA 144
                     R P  P  +     G+ RG G       ++P+ +      G    EE  AA
Sbjct: 1470 --------GRPPSAPADKDGSKPGRTRGDGALQSLCLTTPTEEAVYCFYGNDSDEEPPAA 1521

Query: 145  APAPTSRGHRTEKR--KPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPT 202
            AP PT R      R    ++PQ R  A    +    + P A  Q +   +E      + +
Sbjct: 1522 APTPTHRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAPPPARTQPSLIADETPPCYSLSS 1581

Query: 203  SRGHRTEKRKRQQPQCRPAA---------GTGQRRGSRSSPSADQQRAQDREEEAAAAPA 253
            S    +E    + P   P           G G  R S  SP A ++  Q     A     
Sbjct: 1582 SASSLSEPEPSEPPAVHPRGREPAVTKDPGPGGGRDSSPSPRAAEELLQRCISSALPRRR 1641

Query: 254  PTSSGHRTEK 263
            P  SG R  K
Sbjct: 1642 PPVSGLRRRK 1651



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 64/281 (22%), Positives = 101/281 (35%), Gaps = 62/281 (22%)

Query: 44   AGGTG------QRRGSGSSPSADQ-QGAQDREEE------AAAAPAADQQRAQDREEEAA 90
            AGG G      +RR  G +P+  + +GA D+E E       AA PA  ++ A        
Sbjct: 1308 AGGAGLHFAGHRRREEGPAPTGSRPRGAADQELELLRECLGAAVPARLRKVASALVPGRR 1367

Query: 91   AAPAP----------------------------TSSGHRTEKRKPQQPQCRPAGGTGQRR 122
            A P P                            +S+   +++     P+ +P G  G++R
Sbjct: 1368 ALPVPVYMLVPAPAPAQEDDSCTDSAEGTPVNFSSAASLSDETLQGPPRDQPGGPAGRQR 1427

Query: 123  GSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSR---- 178
             +G   SA Q      +   A   A  SRG    +   + P  RP +    + GS+    
Sbjct: 1428 PTGRPTSARQAMGHRHKAGGAGRSAEQSRGAGKNRAGLELPLGRPPSAPADKDGSKPGRT 1487

Query: 179  -----------SSPSADQ----QGAQDREEEAAAAPVPTSRGHRTEKR--KRQQPQCRPA 221
                       ++P+ +      G    EE  AAAP PT R      R   R++PQ R  
Sbjct: 1488 RGDGALQSLCLTTPTEEAVYCFYGNDSDEEPPAAAPTPTHRRTSAIPRAFTRERPQGRKE 1547

Query: 222  AGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTE 262
            A    +    + P A  Q +   +E        +S+   +E
Sbjct: 1548 APAPSKAAPAAPPPARTQPSLIADETPPCYSLSSSASSLSE 1588


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 59/251 (23%), Positives = 101/251 (40%), Gaps = 33/251 (13%)

Query: 24  WLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA----ADQ 79
           WL++ K     P+++ Q   A G   ++    + S+D + + + EEE    PA       
Sbjct: 57  WLKSAKV----PERKLQ---ANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPA 109

Query: 80  QRAQDREEEAAAAPAPTSSGHRT--------EKRKPQQ----PQCRPAGGTGQRRGSGSS 127
           +R      +AAA  + +SS   +        +K++P Q    PQ + A    ++  S  S
Sbjct: 110 KRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDS 169

Query: 128 PSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR-PAAGTGQRRGSRSSPSADQQ 186
              D   + + E      P  T    + + + P +P R  P    G+   S SS S+   
Sbjct: 170 ---DSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSS 226

Query: 187 GAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREE 246
                EE+AAA P       +T  +K+   +    A T   R S SS  +     +++++
Sbjct: 227 SDDSEEEKAAATP------KKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKK 280

Query: 247 EAAAAPAPTSS 257
                P P SS
Sbjct: 281 PMKNKPGPYSS 291



 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 52/259 (20%), Positives = 100/259 (38%), Gaps = 29/259 (11%)

Query: 6   KEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQ--PAGGTGQRRGSGSSPSADQQG 63
           K   T  RK   S +     E E+ KP++ +  P     P      ++  G+ P   ++ 
Sbjct: 255 KAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPP--KKA 312

Query: 64  AQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRG 123
            + ++   ++  ++D+  +   EE+     A  S    T K  P            ++  
Sbjct: 313 VEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKA--TTKPPP-----------AKKAA 359

Query: 124 SGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKR--------KPQQPQRRPAAGTGQRR 175
             SS S+D   ++D  +EA + PA T++    +          KP    ++P  G  +  
Sbjct: 360 ESSSDSSDSDSSED--DEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLL 417

Query: 176 GSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPS 235
             ++  S+ ++ +   EEE     V T++   T K     P     A  G R  S  S S
Sbjct: 418 TRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLP--AKQAPQGSRDSSSDSDS 475

Query: 236 ADQQRAQDREEEAAAAPAP 254
           +  +  +++  ++A    P
Sbjct: 476 SSSEEEEEKTSKSAVKKKP 494



 Score = 44.7 bits (104), Expect = 9e-05
 Identities = 55/262 (20%), Positives = 93/262 (35%), Gaps = 56/262 (21%)

Query: 17  ESSEGDQ-------WLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREE 69
           +SSE D+         +N   KP    + P  +PA    Q  G G      +  +   EE
Sbjct: 369 DSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEE 428

Query: 70  EAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPS 129
           E++++           EEE       T+    T K     P  +   G+       SS  
Sbjct: 429 ESSSS-----------EEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRD-----SSSD 472

Query: 130 ADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ------PQRRPAAGTGQRRGSRSSPSA 183
           +D   +++ EE+ + +           K+KPQ+      P +  +A  G+   S SS S 
Sbjct: 473 SDSSSSEEEEEKTSKSAV---------KKKPQKVAGGAAPSKPASAKKGKAESSNSSSSD 523

Query: 184 DQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQD 243
           D    ++ + +   +P               +PQ   A GT          +   + +++
Sbjct: 524 DSSEEEEEKLKGKGSP---------------RPQAPKANGTSALTAQNGKAA---KNSEE 565

Query: 244 REEEAAAAPAPTSSGHRTEKRK 265
            EEE   A    S     +KRK
Sbjct: 566 EEEEKKKAAVVVSKSGSLKKRK 587



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 55/249 (22%), Positives = 90/249 (36%), Gaps = 41/249 (16%)

Query: 17  ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA 76
           E S  D   E++K +P++   +PQ + A    ++  S  S         D +  +   P 
Sbjct: 130 EESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDS---------DSDSSSEDEPP 180

Query: 77  ADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQP-QCRPAGGTGQRRGSGSSPSADQQGA 135
            +Q+            P  T    + + + P +P +  P    G+   S SS S+     
Sbjct: 181 KNQK------------PKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSD 228

Query: 136 QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEA 195
              EE+AAA P  T    +   + P +     AA T  R+ S S  S+        EEE 
Sbjct: 229 DSEEEKAAATPKKTVPKKQVVAKAPVK-----AATTPTRKSSSSEDSSSD------EEEE 277

Query: 196 AAAPVPTSRGHRTEKRKRQQPQCRPAAGT--------GQRRGSRSSPSADQQRAQDREEE 247
              P+    G  +       P  + + GT         Q+    S  S+D+  +   EE+
Sbjct: 278 QKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEK 337

Query: 248 AAAAPAPTS 256
                A  S
Sbjct: 338 KPPTKAVVS 346



 Score = 36.6 bits (83), Expect = 0.023
 Identities = 38/176 (21%), Positives = 65/176 (36%), Gaps = 26/176 (14%)

Query: 10  TRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGT---------GQRRGSGSSPSAD 60
           TR      S E     E EKTK +    +P+                G R  S  S S+ 
Sbjct: 418 TRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSS 477

Query: 61  QQGAQDREEEAA-----------AAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQ- 108
            +  +++  ++A           AAP+      + + E + ++ +  SS    EK K + 
Sbjct: 478 SEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKG 537

Query: 109 --QPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ 162
             +PQ   A GT          +   + +++ EEE   A    S+    +KRK  +
Sbjct: 538 SPRPQAPKANGTSALTAQNGKAA---KNSEEEEEEKKKAAVVVSKSGSLKKRKQNE 590



 Score = 32.0 bits (71), Expect = 0.57
 Identities = 27/107 (25%), Positives = 44/107 (41%), Gaps = 4/107 (3%)

Query: 18  SSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAA 77
           SS  D   E E+    +   +PQ   A GT       +  +A     ++ E++ AA   +
Sbjct: 520 SSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQ-NGKAAKNSEEEEEEKKKAAVVVS 578

Query: 78  DQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGS 124
                + R++  AA  A T    + +K K Q P   P    G++R S
Sbjct: 579 KSGSLKKRKQNEAAKEAETP---QAKKIKLQTPNTFPKRKKGEKRAS 622


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 70/287 (24%), Positives = 108/287 (37%), Gaps = 39/287 (13%)

Query: 16   RESSEGDQWLENE-KTK-PLRPQQQ----PQCQPAGGTGQRRG-SGSSPSAD-------- 60
            +E SE D   +++ KT+ PLR + +    P+         RR  SGSSP           
Sbjct: 1554 QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPR 1613

Query: 61   -QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTG 119
             Q G+    E  A AP A  +R++         P+P  S   TE      P+ R A    
Sbjct: 1614 AQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSS-TESSPEHPPKSRTARRGS 1672

Query: 120  Q--------------RRGSGSSPSADQQGAQDREEEAAAA-PAPTSRGHRTEKRKPQQPQ 164
            +              RR S SSP   ++    R   +A++ P   SR     +R P    
Sbjct: 1673 RSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSS 1732

Query: 165  RRPA--AGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAA 222
              PA  + + +RR S SSP       + R        +  SR  R+ + K +  + R  +
Sbjct: 1733 PEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRS-RSRREKTRTTRRRDRS 1791

Query: 223  GTGQRRGSRSSPSADQQRAQDREEEAAA----APAPTSSGHRTEKRK 265
            G+ Q    R   S  + R   R    +     +PA   S   + +R+
Sbjct: 1792 GSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRR 1838



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 51/230 (22%), Positives = 93/230 (40%), Gaps = 27/230 (11%)

Query: 47  TGQRRG-SGSSPSADQQGAQDREEEAAAAPAAD-QQRAQDREEEAAAAPAPTSSGHRTEK 104
           T QRR  S SSP   +     R   + ++P +  + R   R   + ++P P        K
Sbjct: 736 TSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCP--------K 787

Query: 105 RKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRK--PQQ 162
           +K Q P  R   G+ Q +    +P         R   ++++P P  +     ++      
Sbjct: 788 QKSQTPPRRSRSGSSQPKAKSRTPP--------RRSRSSSSPPPKQKSKTPSRQSHSSSS 839

Query: 163 PQRRPAAGTGQRRGSRSSPSADQQGAQDREE---EAAAAPVPTSRGHRTEKRKRQQPQCR 219
           P  +  +GT  R+GS +SP A++Q    +     E++  P   SR           P   
Sbjct: 840 PHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRV 899

Query: 220 PAAGTGQRRGSRSSPSADQQRA----QDREEEAAAAPAPTSSGHRTEKRK 265
            ++   ++  SRSS    + +A    + R    +++P+P+    RT  R+
Sbjct: 900 KSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR 949



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 57/233 (24%), Positives = 88/233 (37%), Gaps = 21/233 (9%)

Query: 32   PLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAA 91
            P  P+   +C     T QR  SGS  S DQ+         A  P   + R+   +E    
Sbjct: 1500 PSSPELNNKCL----TPQRERSGSESSVDQK-------TVARTPLGQRSRSGSSQELDVK 1548

Query: 92   APAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQG-AQDREEEAAAAPAPTS 150
              A  S   R+E       + +      QR  SGSSP  D +     R   + ++P    
Sbjct: 1549 PSA--SPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD 1606

Query: 151  R---GHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQ---DREEEAAAAPVPTSR 204
            +     R +      P+ +  A     R SRS  S+  +G         E++    P SR
Sbjct: 1607 KPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSR 1666

Query: 205  GHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSS 257
              R   R   +P+ + +    +RR SRSSP   ++    R   +A++   T S
Sbjct: 1667 TARRGSRSSPEPKTK-SRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRS 1718



 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 60/227 (26%), Positives = 90/227 (39%), Gaps = 29/227 (12%)

Query: 49   QRRGSGSSPSA-DQQGAQDREEEAAAAPAA-DQQRAQDR-EEEAAAAPAPTSSGH--RTE 103
            +R  SGSSP   D  G   R   + ++P   D  R   R   E  ++P P +     R  
Sbjct: 1437 RRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPR 1496

Query: 104  KRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQP 163
             R P  P+      T QR  SGS  S DQ+             A T  G R+     Q+ 
Sbjct: 1497 SRSPSSPELNNKCLTPQRERSGSESSVDQK-----------TVARTPLGQRSRSGSSQEL 1545

Query: 164  QRRPAAGTGQRRGSRSSP--SADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQ----QPQ 217
              +P+A   +R  S SSP   A  +    +   + ++P   S+   + +R R     + +
Sbjct: 1546 DVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVK 1605

Query: 218  CRPAAGTGQRRGSRSS--PSADQQRAQDREEEAAAA-----PAPTSS 257
             +P A    + GS SS  P A   RA  R   + ++     P+P  S
Sbjct: 1606 DKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGS 1652



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 44/240 (18%), Positives = 82/240 (34%), Gaps = 21/240 (8%)

Query: 31   KPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAA 90
            +P + ++      +  +     S SS S+   G+   + E ++ P   +   +       
Sbjct: 2525 QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALK-----RV 2579

Query: 91   AAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTS 150
             +P P       E R P+     P     +RR S SS S+    +      ++++ + +S
Sbjct: 2580 PSPTPAPKEAVREGRPPE-----PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2634

Query: 151  RGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRT-- 208
                +           PA    Q     +SP     G  +R   +   P+ + R  R+  
Sbjct: 2635 SSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG--ERRSRSPRKPIDSLRDSRSLS 2692

Query: 209  -----EKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEK 263
                  +R   QP  R    +   RGSR     D +    +      +P P    HR+ +
Sbjct: 2693 YSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMR--HRSSR 2750



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 36/185 (19%), Positives = 77/185 (41%), Gaps = 14/185 (7%)

Query: 85  REEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDRE----- 139
           +EE     PA T +    E  + +  + R A G       GSS    ++  + ++     
Sbjct: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEP 167

Query: 140 -------EEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDRE 192
                   E++++ +PT +  + +K+K +   RR  + + +R   +SS     +   + +
Sbjct: 168 PKPYSLVRESSSSRSPTPK--QKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESK 225

Query: 193 EEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAP 252
           +    +P P S+    +K++++     PA  + +   S S+ SA           +AAA 
Sbjct: 226 KRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAK 285

Query: 253 APTSS 257
             T++
Sbjct: 286 THTTA 290



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 53/227 (23%), Positives = 88/227 (38%), Gaps = 23/227 (10%)

Query: 55  SSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRP 114
           SSP  D+   +D++E++A  P+   +R+          PAPT          PQ     P
Sbjct: 332 SSPYEDKD--KDKKEKSATRPSPSPERSST----GPEPPAPTPLLAERHGGSPQPLATTP 385

Query: 115 AGGTGQRRGSGSSPSADQQGAQDRE--------EEAAAAPAPTSRGHRTEKRKPQQPQRR 166
                    S +SP+ D+   +  E        E +  +P PT +  R     P+ P+  
Sbjct: 386 LSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPT-KVSRHASSSPESPKPA 444

Query: 167 PAAGTGQRRGSRSSPSADQQGAQDREEEAAAAP---VPTSRGHRTEKRKRQQPQCRPAAG 223
           PA G+ +   S  +      G   R++  +  P   +  SR   T KR R + +     G
Sbjct: 445 PAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRG 504

Query: 224 -----TGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKRK 265
                + Q R SRS+    + R+  R   + +   P  S  R  +R+
Sbjct: 505 HSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRR 551



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 56/247 (22%), Positives = 99/247 (40%), Gaps = 30/247 (12%)

Query: 26  ENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDR 85
           E  +   L  ++  + + A G       GSS   D Q    R    A  PA +  +    
Sbjct: 120 ETHQLAELNEKKNERLRAAFGISDSYVDGSS--FDPQ----RRAREAKQPAPEPPKPYSL 173

Query: 86  EEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAA 145
             E++++ +PT    + +K+K +  +   +    +R+ S    S  ++   + E +    
Sbjct: 174 VRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKS----SKKKKHRSESESKKRKH 229

Query: 146 PAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQD----REEEAAAAPVP 201
            +PT +  R  K K ++  R        RR  RS+ SAD   + D    R   AAA    
Sbjct: 230 RSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRST-SADSASSSDTSRSRSRSAAAKTHT 288

Query: 202 TSRGHRT------EKRKRQQPQCRPAAGTGQRRGS-------RSSPSADQQRAQDREEEA 248
           T+   R+       + +   P   P   + QR  S        SSP  D+ +  D++E++
Sbjct: 289 TALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDK--DKKEKS 346

Query: 249 AAAPAPT 255
           A  P+P+
Sbjct: 347 ATRPSPS 353



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 48/230 (20%), Positives = 81/230 (35%), Gaps = 13/230 (5%)

Query: 49  QRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQ 108
           QRRG   SP           +    + +A + R+  R           +   R   R   
Sbjct: 529 QRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRT 588

Query: 109 QPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPA 168
             + R    T  RR S S   A +  ++ R      +   +    R+  R P +   R  
Sbjct: 589 PARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSR 648

Query: 169 AGTGQRRGSRSSPSADQQG-----AQDREEEAAAAPVPTSRGH---RTEKRKRQQPQC-- 218
           + T  RRG   S +  ++G        R    + +  P  RG    RT +R R + +   
Sbjct: 649 SRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLV 708

Query: 219 ---RPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKRK 265
              R  + T QRRG   S S  + +++  +  + +  +P     R   R+
Sbjct: 709 RRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRR 758



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 51/268 (19%), Positives = 91/268 (33%), Gaps = 25/268 (9%)

Query: 10  TRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREE 69
           T  R+ R  S       +    P R + + +     G  + R      S  +   + R  
Sbjct: 577 TPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSR 636

Query: 70  EAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPS 129
             + A  + + R++       +     +   R+  R P +   R    T  RR  G S S
Sbjct: 637 SRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARR--GRSRS 694

Query: 130 ADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRG-SRSSPSADQQGA 188
              +  + R           SR  +   R     +R+  + T QRR  S SSP   +   
Sbjct: 695 RTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRI 754

Query: 189 QDREEEAAAAPVPTSRGHRT-----------EKRKRQQPQCRPAAGTGQ----------- 226
             R   + ++P   ++   +            K+K Q P  R  +G+ Q           
Sbjct: 755 SSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRR 814

Query: 227 RRGSRSSPSADQQRAQDREEEAAAAPAP 254
            R S S P   + +   R+  ++++P P
Sbjct: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHP 842



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 63/285 (22%), Positives = 104/285 (36%), Gaps = 44/285 (15%)

Query: 1   MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQ---------QQPQC-QPAGGTGQR 50
           + P  +   TR R   +S E      + ++ P  PQ           P+  +PA   G  
Sbjct: 391 VNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSH 450

Query: 51  RGSGSSPSADQQ--GAQDREEEAAAAPAADQQRAQD---REEEAAAAPAPTSSGH----- 100
           R   SSP++  +  G   R++  +  P+    R++     +   + +  PT  GH     
Sbjct: 451 REISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRS 510

Query: 101 --------------------RTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREE 140
                               R   R PQ+P    +  T QRRG   S    +  ++    
Sbjct: 511 PQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNT-QRRGRSRSARRGRSHSRSPAT 569

Query: 141 EAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPV 200
              +     +R  R+  R P   +RR  + T  RR SRS   A +  ++ R      +  
Sbjct: 570 RGRSRSRTPARRGRSRSRTP--ARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRT 627

Query: 201 PTSRGHRTEKRKRQQPQCRPAAGTGQRRG-SRSSPSADQQRAQDR 244
            +    R+  R   +   R  + T  RRG SRS   A + R++ R
Sbjct: 628 RSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSR 672



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 35/175 (20%), Positives = 66/175 (37%), Gaps = 13/175 (7%)

Query: 63   GAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRR 122
            GAQ     AA  PA +++ +      ++++ + +SS   +            + G+    
Sbjct: 2514 GAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS-----------SSGSSSSD 2562

Query: 123  GSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPS 182
              GSS     + A  R      AP    R  R  +  P + +RR ++ +     S SS S
Sbjct: 2563 SEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSS 2622

Query: 183  ADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQC--RPAAGTGQRRGSRSSPS 235
            +    +      ++++   +S    +    +  PQ   +PA+      G R S S
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRS 2677



 Score = 37.0 bits (84), Expect = 0.018
 Identities = 50/241 (20%), Positives = 90/241 (37%), Gaps = 23/241 (9%)

Query: 2    KPRQKEQDTRLRKLRESSEGDQWLENEKTKPL-RPQQQPQCQPAGGTGQRRGSGSSPSAD 60
            + R +   TR R    +    +     +T P+ R + + +  P   T +R  S +SP   
Sbjct: 1934 RSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPI--TRRRSRSRTSPVTR 1991

Query: 61   QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ 120
            ++    R   +       + R        + +  P +   R+  R P  P+         
Sbjct: 1992 RRS---RSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPR--------- 2039

Query: 121  RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS 180
            +R    SP A ++ ++ R          T+RG R+  R P   +RR A+G+   R   ++
Sbjct: 2040 KRSRSRSPLAIRRRSRSRTPR-------TARGKRSLTRSPPAIRRRSASGSSSDRSRSAT 2092

Query: 181  PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240
            P A +  +  R    A      S   R         +CR + G  +  GS  +P +  Q+
Sbjct: 2093 PPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCR-SPGMLEPLGSSRTPMSVLQQ 2151

Query: 241  A 241
            A
Sbjct: 2152 A 2152



 Score = 33.5 bits (75), Expect = 0.20
 Identities = 50/249 (20%), Positives = 97/249 (38%), Gaps = 40/249 (16%)

Query: 2    KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQ 61
            + R +   TR R    +S   +     +T P+  ++     P   T +RR    +P   +
Sbjct: 1899 RSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTP---TTRRRSRSRTPPVTR 1955

Query: 62   QGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQR 121
            + ++ R       P   ++R++ R        + + +   T +R     + R +  T +R
Sbjct: 1956 RRSRSR------TPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRS----RSRTSPVTRRR 2005

Query: 122  RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRS-S 180
              S +SP   ++         + +  P +   R+  R P  P++R          SRS S
Sbjct: 2006 SRSRTSPVTRRR---------SRSRTPPAIRRRSRSRTPLLPRKR----------SRSRS 2046

Query: 181  PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240
            P A ++ ++ R          T+RG R+  R     + R A+G+   R   ++P A +  
Sbjct: 2047 PLAIRRRSRSRTPR-------TARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNH 2099

Query: 241  AQDREEEAA 249
            +  R    A
Sbjct: 2100 SGSRTPPVA 2108



 Score = 32.0 bits (71), Expect = 0.57
 Identities = 34/190 (17%), Positives = 66/190 (34%), Gaps = 20/190 (10%)

Query: 2   KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQ 61
           +P+ K +    R    SS   +      ++       P  +   GT  R+GS +SP A++
Sbjct: 803 QPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANE 862

Query: 62  QGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRK------PQQPQCRPA 115
           Q    +      +    + +++     + +  +P      T  R+        QP+ +  
Sbjct: 863 QSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAI 922

Query: 116 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSR--------------GHRTEKRKPQ 161
               QR  SGSS  +  +         + + +P S                    K KP+
Sbjct: 923 ISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPE 982

Query: 162 QPQRRPAAGT 171
            P R+  +G+
Sbjct: 983 TPPRQSHSGS 992


>gi|153070260 myristoylated alanine-rich protein kinase C substrate
           [Homo sapiens]
          Length = 332

 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 58/252 (23%), Positives = 104/252 (41%), Gaps = 44/252 (17%)

Query: 39  PQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSS 98
           P    +G   + + +GS+P+AD      +EE AAA   A    A ++ E AAAA AP + 
Sbjct: 47  PAAAESGAKEELQANGSAPAAD------KEEPAAAGSGAASPSAAEKGEPAAAA-APEAG 99

Query: 99  GHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSR------- 151
               EK  P + +    G      G  +S ++        + E  A P+P++        
Sbjct: 100 ASPVEKEAPAEGEAAEPGSPTAAEGEAASAAS---STSSPKAEDGATPSPSNETPKKKKK 156

Query: 152 -----------GHRTEKRKPQQPQ----RRPAA--GTGQRRGSRSSPSADQQGAQDRE-- 192
                      G   +K K +  +      PAA  G  +  G  ++ +A+   A   +  
Sbjct: 157 RFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAA 216

Query: 193 ---EEAAAAPVPTSRGHRTEKRKRQ---QPQCRPAAGTGQRRGSRSSPSADQQRAQDREE 246
              EEAAA     + G   E + ++    P+  PA  + + + +      ++++A++   
Sbjct: 217 APGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPA--SDETKAAEEPSKVEEKKAEEAGA 274

Query: 247 EAAAAPAPTSSG 258
            AAA  AP+++G
Sbjct: 275 SAAACEAPSAAG 286



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 52/216 (24%), Positives = 90/216 (41%), Gaps = 29/216 (13%)

Query: 55  SSPSADQQGAQDREEEAAAAPAADQQRAQDR---EEEAAAAPAPTSSGHRTEKRKPQQPQ 111
           S  +A  + A +R  EAA A +  +   Q+    +    A+PA   SG    K + Q   
Sbjct: 6   SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESG---AKEELQANG 62

Query: 112 CRPAGGTGQRRGSGS---SPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQR--- 165
             PA    +   +GS   SPSA ++G      E AAA AP +     EK  P + +    
Sbjct: 63  SAPAADKEEPAAAGSGAASPSAAEKG------EPAAAAAPEAGASPVEKEAPAEGEAAEP 116

Query: 166 -RPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGT 224
             P A  G+   + SS S+        + E  A P P++   + +K++    +    +G 
Sbjct: 117 GSPTAAEGEAASAASSTSSP-------KAEDGATPSPSNETPKKKKKRFSFKKSFKLSGF 169

Query: 225 GQRRGSRSS---PSADQQRAQDREEEAAAAPAPTSS 257
             ++  + +     A+   A+  ++EAA   A  ++
Sbjct: 170 SFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAA 205



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 48/229 (20%), Positives = 91/229 (39%), Gaps = 28/229 (12%)

Query: 28  EKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREE 87
           EK  P   +      P    G+   + SS S+ +        E  A P+   +  + +++
Sbjct: 104 EKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKA-------EDGATPSPSNETPKKKKK 156

Query: 88  EAAAAPAPTSSGHRTEKRKPQ-----QPQCRPAGGTGQRRGSGSSPSADQQGAQDREE-- 140
             +   +   SG   +K K +     + +   A G       G++ +A + GA   E+  
Sbjct: 157 RFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAA 216

Query: 141 ---EAAAAPAPTSRGHRTEKRKPQQ----PQRRPAAGTGQRRGSRSSPSADQQGAQDREE 193
              E AAA    + G   ++ KPQ+    P++ PA+   + + +      +++ A++   
Sbjct: 217 APGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASD--ETKAAEEPSKVEEKKAEEAGA 274

Query: 194 EAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQ 242
            AAA   P++ G      +   P   PAA       + S+ +A  Q AQ
Sbjct: 275 SAAACEAPSAAGPGAPPEQEAAPAEEPAAA-----AASSACAAPSQEAQ 318



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 35/152 (23%), Positives = 62/152 (40%), Gaps = 8/152 (5%)

Query: 52  GSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREE----EAAAAPAPTSSGHRTEKRKP 107
           G   +P+A+  G +D     AAA AA+   A   +     E AAA    ++G   ++ KP
Sbjct: 182 GEAEAPAAE--GGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKP 239

Query: 108 QQPQCRPAG--GTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQR 165
           Q+    P     + + + +      +++ A++    AAA  AP++ G      +   P  
Sbjct: 240 QEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAE 299

Query: 166 RPAAGTGQRRGSRSSPSADQQGAQDREEEAAA 197
            PAA       +  S  A  + + +     AA
Sbjct: 300 EPAAAAASSACAAPSQEAQPECSPEAPPAEAA 331



 Score = 32.0 bits (71), Expect = 0.57
 Identities = 25/105 (23%), Positives = 45/105 (42%), Gaps = 5/105 (4%)

Query: 44  AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA-ADQQRAQDREEEAAAAPAPTSSGHRT 102
           AGG  Q      +  A ++     E +AA  P+  ++++A++    AAA  AP+++G   
Sbjct: 230 AGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAG--- 286

Query: 103 EKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA 147
               P + +  PA        S +  +  Q+   +   EA  A A
Sbjct: 287 -PGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEA 330


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 56/220 (25%), Positives = 86/220 (39%), Gaps = 26/220 (11%)

Query: 44   AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTE 103
            A GTG++R S  SP    Q  QD+    A + +     AQ +  + +A P P     +T+
Sbjct: 2232 AAGTGEQRQSKLSPQ--MQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQP-----QTQ 2284

Query: 104  KRKPQQP--QCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQ 161
             + P QP  Q +P   T     S     A    AQ  + + AA   P S        + Q
Sbjct: 2285 PQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQ 2344

Query: 162  QPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRP- 220
             P         Q R   S+PS    G Q + +   + P+P       +   + QPQ +P 
Sbjct: 2345 SPS--------QTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQ 2396

Query: 221  --------AAGTGQRRGSRSSPSADQQRAQDREEEAAAAP 252
                    ++G    + + SSPS  Q + Q  + +  A P
Sbjct: 2397 VQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVP 2436



 Score = 34.7 bits (78), Expect = 0.088
 Identities = 35/118 (29%), Positives = 43/118 (36%), Gaps = 25/118 (21%)

Query: 62  QGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQR 121
           +G + R  +  AAPAA         E  A AP P           P  P   P GG   R
Sbjct: 2   RGRRGRPPKQPAAPAA---------ERCAPAPPPP----------PPPPTSGPIGGLRSR 42

Query: 122 -RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSR 178
            RGS     A  Q      E A      + RG  + +RKP  P   P + +   RG R
Sbjct: 43  HRGSSRGRWAAAQA-----EVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGGR 95


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 52/251 (20%), Positives = 97/251 (38%), Gaps = 15/251 (5%)

Query: 17   ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA 76
            + +EG+   E+E  +    +++ Q +  G         + P  + +G +  E E  A P 
Sbjct: 2151 QDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQP--ESEGIEAPEAEGEAQPE 2208

Query: 77   ADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGT-GQRRGSGSSPSADQQGA 135
             +   A + EEEA   P    +     + +P+       G T G+++GS   P       
Sbjct: 2209 LEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESE-----GETQGEKKGS---PQVSLGDG 2260

Query: 136  QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEA 195
            Q  E   +++P P  R           P +RP + TG      SS     Q   + +   
Sbjct: 2261 QSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVL 2320

Query: 196  AAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRR----GSRSSPSADQQRAQDREEEAAAA 251
                 P ++   T   +R+  +  P + T ++     GSR+      +    +E++A  +
Sbjct: 2321 GDTRSPDAKSTGTPHAERKATRMYPESSTSEQEEAPLGSRTPEQGASEGYDLQEDQALGS 2380

Query: 252  PAPTSSGHRTE 262
             APT +  R +
Sbjct: 2381 LAPTEAVGRAD 2391



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 41/199 (20%), Positives = 72/199 (36%), Gaps = 12/199 (6%)

Query: 35   PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPA 94
            P+ + + QP     +   +      + +G + ++ E  A P ++   AQ+ EEEA     
Sbjct: 2119 PETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELE 2178

Query: 95   PTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHR 154
               +     + +P+          G+     + P  +   A + EEEA     P   G  
Sbjct: 2179 GVEAPEAEGEAQPESEGIEAPEAEGE-----AQPELEGVEAPEAEEEA----QPEPEGVE 2229

Query: 155  TEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQ 214
            T + + +          G+++G   SP       Q  E   +++PVP  R          
Sbjct: 2230 TPEAEGEAQPESEGETQGEKKG---SPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGD 2286

Query: 215  QPQCRPAAGTGQRRGSRSS 233
             P  RP + TG      SS
Sbjct: 2287 TPHQRPGSQTGPSSSRASS 2305



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 47/242 (19%), Positives = 86/242 (35%), Gaps = 9/242 (3%)

Query: 17   ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA 76
            E+ E +  ++ E      P+ + + QP   + +   +      + +GA+ +E E AA  A
Sbjct: 1891 ETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEA 1950

Query: 77   ADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQ 136
              Q + +    E+  A           +    + + + A G  Q           +   Q
Sbjct: 1951 EGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQ 2010

Query: 137  DREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAA 196
            + EEEA     P S G   +  K +  + +   G  Q+    + P +D   A + EEEA 
Sbjct: 2011 EAEEEA----QPESDGVEAQP-KSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQ 2065

Query: 197  AAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTS 256
             A             + +    + A G  Q      S   +   A+   ++A    AP +
Sbjct: 2066 EAEGEVQEAEGEAHPESEDVDAQEAEGEAQ----PESEGVEAPEAEGEAQKAEGIEAPET 2121

Query: 257  SG 258
             G
Sbjct: 2122 EG 2123



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 53/234 (22%), Positives = 86/234 (36%), Gaps = 29/234 (12%)

Query: 46   GTGQRRGSGSSPSADQQGAQ--DREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTE 103
            G G  +G G     D +G+Q  +R+++     A     AQ+R  E     + TS+G    
Sbjct: 1731 GPGLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQER--EGKTHNSETSAGSELG 1788

Query: 104  KRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEE------AAAAPAPTSRGH-RTE 156
            + + +       G TG  +GSG   +   + A   +++      A    AP + G  + E
Sbjct: 1789 EAEQEGEGISERGETG-GQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPE 1847

Query: 157  KRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAP------------VPTSR 204
                + P+   A G  Q     + P ++   A + E EA                 P S 
Sbjct: 1848 SEGVEAPE---AEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESE 1904

Query: 205  G-HRTEKRKRQQPQCRPA-AGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTS 256
            G    E  K  QP+     A   +      S  A+ Q A++  +EA     P S
Sbjct: 1905 GAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPES 1958



 Score = 34.3 bits (77), Expect = 0.12
 Identities = 62/247 (25%), Positives = 83/247 (33%), Gaps = 36/247 (14%)

Query: 29  KTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEE 88
           K  P  P+++  CQ   G+  R    SS +  Q     R   + + P+      QD    
Sbjct: 684 KQVPRPPERRRACQD--GSVPRYSGSSSSTRTQASGNLRPPSSGSLPS------QDLLGT 735

Query: 89  AAAAPAPTSSGHRTEKRKPQQ-PQCRPAGGTGQRRGSGS------SPSADQQGAQDREEE 141
           ++A   P           P   P    AG  G R  S +      S S  + GA    EE
Sbjct: 736 SSATVTPAVHSDFVSGVSPHNAPSAGWAGDAGSRTCSPAPIPPHTSDSCSKSGAASLGEE 795

Query: 142 AAAAPAPTSRGHRTEKRKPQQPQ-RRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPV 200
           A   P P+S         P   Q  RP  G     G   S    Q G Q   +EA   P 
Sbjct: 796 ARDTPQPSS---------PLVLQVGRPEQGA---VGPHRSHCCSQPGTQP-AQEAQRGPS 842

Query: 201 PTS-----RGHRTEKRKRQQPQCRPAA--GTGQRRGSRSSPSADQQRAQDREEEAAAAPA 253
           P +     R   T  R R  PQ R ++   TG    S +       +   R+     +P 
Sbjct: 843 PEASWLCGRYCPTPPRGRPCPQRRSSSCGSTGSSHQSTARGPGGSPQEGTRQPGPTPSPG 902

Query: 254 PTSSGHR 260
           P S   R
Sbjct: 903 PNSGASR 909


>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
            containing 1 isoform c [Homo sapiens]
          Length = 1462

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 44/179 (24%), Positives = 76/179 (42%), Gaps = 12/179 (6%)

Query: 46   GTGQRRGSGSSPSADQ--QGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPT-SSGHRT 102
            GT ++  SG+    D+  +G +D + E AAA    ++R+ ++  E   +   T     + 
Sbjct: 1284 GTSRKPDSGACRPKDRAPEGRRDAQAERAAAANGPKRRSPEKRREGTRSADNTLERREKH 1343

Query: 103  EKRKPQQPQCRPAGGTGQRRGSGSS---PSADQQGAQDREEEAAAAPAPTSRGHRTEKRK 159
            EKR+   P+ R      +RR    S    S ++   Q R  E     +P  R   T++R+
Sbjct: 1344 EKRRDVSPERRRERSPTRRRDGSPSRRRRSLERLLEQRRSPERRRGGSPERRAKSTDRRR 1403

Query: 160  PQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQC 218
             + P+RR      +R         D+   ++REE         S  H  E+R+R   +C
Sbjct: 1404 ARSPERRRERSLDKRN------REDRASHREREEANLKQDAGRSSRHPPEQRRRPYKEC 1456



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 60/257 (23%), Positives = 96/257 (37%), Gaps = 32/257 (12%)

Query: 21   GDQWLE--NEKTKPLRPQQQPQCQPAGGTGQR----RGSGSSPSADQQGAQDREEEAAAA 74
            GD+ LE   E TK ++  +  +    GG   R    RG GS P  D   + DR   A   
Sbjct: 1167 GDEILEINGETTKNMKHSRAIELIKNGGRRVRLFLKRGDGSVPEYDP--SSDRHGPATGP 1224

Query: 75   PAADQQRA-QDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQ- 132
                + RA  DR +  +   +     H++     ++   R   G+   R     P+    
Sbjct: 1225 QGVPEVRAGPDRRQHPSLESSYPPDLHKSSPHGEKRAHARDPKGS---REYSRQPNEHHT 1281

Query: 133  -QGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDR 191
              G   + +  A  P    +    E R+  Q +R  AA   +RR    SP   ++G +  
Sbjct: 1282 WNGTSRKPDSGACRP----KDRAPEGRRDAQAERAAAANGPKRR----SPEKRREGTR-- 1331

Query: 192  EEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRG---SRSSPSADQQRAQDREEEA 248
                 +A     R  + EKR+   P+ R      +RR    SR   S ++   Q R  E 
Sbjct: 1332 -----SADNTLERREKHEKRRDVSPERRRERSPTRRRDGSPSRRRRSLERLLEQRRSPER 1386

Query: 249  AAAPAPTSSGHRTEKRK 265
                +P      T++R+
Sbjct: 1387 RRGGSPERRAKSTDRRR 1403



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 25/113 (22%), Positives = 44/113 (38%), Gaps = 5/113 (4%)

Query: 5    QKEQDTRLRKLRESS-----EGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSA 59
            +K +D    + RE S     +G         + L  Q++   +  GG+ +RR   +    
Sbjct: 1344 EKRRDVSPERRRERSPTRRRDGSPSRRRRSLERLLEQRRSPERRRGGSPERRAKSTDRRR 1403

Query: 60   DQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQC 112
             +   + RE         D+   ++REE      A  SS H  E+R+    +C
Sbjct: 1404 ARSPERRRERSLDKRNREDRASHREREEANLKQDAGRSSRHPPEQRRRPYKEC 1456


>gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B
           subunit [Homo sapiens]
          Length = 2339

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 61/238 (25%), Positives = 88/238 (36%), Gaps = 46/238 (19%)

Query: 5   QKEQDTRLRKLRESSEG-------DQWLENEKTKPLRPQQQPQCQ--------------P 43
           Q+    RL+ LR S E        ++ L    T+ LRP  +                  P
Sbjct: 770 QRASQLRLQNLRASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGP 829

Query: 44  AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAA-DQQRAQDREEEAAAAPAPTSSGHRT 102
            GG  +   + +    D      R  +    PAA DQ RA+  + E+         G R 
Sbjct: 830 VGGKARPEAAEAPEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESG------EPGARE 883

Query: 103 EKRKPQQPQCRPAGGTGQ---RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRK 159
           E+ +P +   + A G  +    RG G  P   ++  +    E AA   P  R HR  +  
Sbjct: 884 ERPRPHRSHSKEAAGPPEARSERGRGPGPEGGRRHHRRGSPEEAAEREP--RRHRAHRH- 940

Query: 160 PQQPQRRPAAGTGQRRG-SRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQP 216
            Q P +  A   G+RR   R  P A  + A+  EE A        R HR   R + QP
Sbjct: 941 -QDPSKECAGAKGERRARHRGGPRAGPREAESGEEPA--------RRHRA--RHKAQP 987


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 64/267 (23%), Positives = 97/267 (36%), Gaps = 49/267 (18%)

Query: 14  KLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAA 73
           K R SS    W      +P  P   P   P      +  S    +A  +G   R+EEA  
Sbjct: 464 KARPSSPSTSW-----HRPASPCPSPG--PGHTLPPKPPSPRGTTASPKGRVRRKEEAKE 516

Query: 74  APAA--------DQQRAQDREEEAAAA---PAPTSSGHRTEKRKPQQPQCRPAGG----T 118
           +P+A         ++RA + +E AA A   P+P  S      +K Q P   P       +
Sbjct: 517 SPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTS 576

Query: 119 GQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSR 178
                   +PS    G  DREE               EKR+  + QR       + +  R
Sbjct: 577 PPAPAPPVTPSKPMAGTTDREEATRLL---------AEKRRQAREQREREEQERRLQAER 627

Query: 179 SSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQ 238
                ++Q A++ E  A             E R+R++ + R  A   Q          +Q
Sbjct: 628 DKRMREEQLAREAEARAE---------REAEARRREEQEAREKAQAEQE---------EQ 669

Query: 239 QRAQDREEEAAAAPAPTSSGHRTEKRK 265
           +R Q ++EEA A     +   R E+ K
Sbjct: 670 ERLQKQKEEAEARSREEAERQRLEREK 696



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 57/246 (23%), Positives = 93/246 (37%), Gaps = 55/246 (22%)

Query: 43  PAGGTGQRRGS--GSSPSADQQGAQ-------DREEEAAAAPAADQQRAQDREEEAAAAP 93
           P  G  Q RG   G  P+  + GA        DR   +AA P   +         A+A+P
Sbjct: 318 PRNGRDQGRGCDPGRGPTWGRAGASLARGPQPDRTHPSAAVPVCPRS--------ASASP 369

Query: 94  APTSSGHRTEKRKPQQPQCRPAGGTGQRR--GSGSSPS----------ADQQGAQDREEE 141
               S  R+  R      C PAG  G+RR   +G SP+            ++  +D+E E
Sbjct: 370 LTPCSVTRSVHR------CAPAGERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERE 423

Query: 142 AAAAPAPTSRGHRTEKRK--PQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAP 199
                +  +R    +KR+  P  P+ R +A T      +S     +  +        A+P
Sbjct: 424 NEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKA---RPSSPSTSWHRPASP 480

Query: 200 VPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGH 259
            P+     T   K   P           RG+ +SP    +R    +EEA  +P+      
Sbjct: 481 CPSPGPGHTLPPKPPSP-----------RGTTASPKGRVRR----KEEAKESPSAAGPED 525

Query: 260 RTEKRK 265
           +++ ++
Sbjct: 526 KSQSKR 531



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 52/244 (21%), Positives = 95/244 (38%), Gaps = 46/244 (18%)

Query: 40  QCQPAGGTGQRR--GSGSSPSA------------DQQGAQDREEEAAAAPAADQQRAQDR 85
           +C PAG  G+RR   +G SP+              ++  ++RE E   +  A ++  + R
Sbjct: 381 RCAPAGERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKR 440

Query: 86  EEEAAAAPAPTSSGHRTE-----KRKPQQPQCR--------PAGGTGQR--------RGS 124
           +   A+  A  S+   +E     K +P  P           P+ G G          RG+
Sbjct: 441 QSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGT 500

Query: 125 GSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSAD 184
            +SP    +G   R+EEA  +P+      +++ ++    ++  AA          SP+  
Sbjct: 501 TASP----KGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPT-- 554

Query: 185 QQGAQDREEEAAAAPVPTSRGHRTEKRKRQQP--QCRPAAGTGQRRGSRSSPSADQQRAQ 242
                  ++E   A  PT     T       P    +P AGT  R  +    +  +++A+
Sbjct: 555 ---PAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAR 611

Query: 243 DREE 246
           ++ E
Sbjct: 612 EQRE 615



 Score = 37.4 bits (85), Expect = 0.014
 Identities = 40/176 (22%), Positives = 73/176 (41%), Gaps = 26/176 (14%)

Query: 7   EQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQD 66
           E+  + R+ RE  E ++ L+ E+ K +R +Q  +        + R    + +  ++  + 
Sbjct: 605 EKRRQAREQREREEQERRLQAERDKRMREEQLAR------EAEARAEREAEARRREEQEA 658

Query: 67  REEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRK--PQQPQCRP---------- 114
           RE+  A A   +Q+R Q ++EEA A     +   R E+ K   QQ Q R           
Sbjct: 659 REK--AQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIM 716

Query: 115 ----AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRK--PQQPQ 164
                    + +    S  A+  G+     +A  A +P  +    +K +  PQ+PQ
Sbjct: 717 KRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEPIPQEPQ 772



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 41/195 (21%), Positives = 66/195 (33%), Gaps = 19/195 (9%)

Query: 56  SPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPA 115
           +PS    G  DREE         +Q  + RE E              +KR  ++   R A
Sbjct: 585 TPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAER----DKRMREEQLAREA 640

Query: 116 GGTGQRRGSGSSPSADQQGAQDREEEAAA--APAPTSRGHRTEKRKPQQPQRRPAAGTGQ 173
               +R             A+ REE+ A   A A      R +K+K +   R       Q
Sbjct: 641 EARAEREAE----------ARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQ 690

Query: 174 RRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQ---RRGS 230
           R          +Q  Q+R +        T +   +E +++Q  +   A G+     +   
Sbjct: 691 RLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVE 750

Query: 231 RSSPSADQQRAQDRE 245
             SP   ++  Q  E
Sbjct: 751 ARSPGLQKEAVQKEE 765


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 50/265 (18%), Positives = 97/265 (36%), Gaps = 4/265 (1%)

Query: 2   KPRQKEQDTRLRKLRE-SSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
           K R +++D    + R+   E ++  + E+ +    ++  Q +    T +    G     D
Sbjct: 85  KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144

Query: 61  QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ 120
            Q  ++R+ +A         R + R+ E           +R E+R+ ++ Q      T  
Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERER-QREKENKTED 203

Query: 121 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS 180
           R          ++  +   E          R  +TE+ + +Q +R  A+     R     
Sbjct: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263

Query: 181 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240
              D+   +DR ++         R  RTE R R+  + R      +R   R+    +++R
Sbjct: 264 RERDRDRDRDRRQKERERQTDRKRQRRTE-RDRETERKRERQRERERERERNR-KRERER 321

Query: 241 AQDREEEAAAAPAPTSSGHRTEKRK 265
            ++RE E            R  KRK
Sbjct: 322 ERERERERQRETERDREKERERKRK 346



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 54/268 (20%), Positives = 108/268 (40%), Gaps = 12/268 (4%)

Query: 4   RQKEQDTRLRKLRESSEGDQW-LENEKTKPLRPQQQPQCQPAGGTGQRRGS-GSSPSADQ 61
           +++E+ T   + R++    Q   E EK +  R +++ Q +    T  R    G     ++
Sbjct: 157 KERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERER 216

Query: 62  QGAQDREEEAAAAPAADQQRA--QDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTG 119
           +   + E +       D+QR   ++RE++A    A      R ++R+ ++ + R      
Sbjct: 217 ETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQ 276

Query: 120 QRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRS 179
           + R   +     ++  +DRE E            R   RK ++ + R      QR   R 
Sbjct: 277 KERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERD 336

Query: 180 SPSADQQGAQDREEEAAAAPVPTSR-GHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQ 238
                ++  + + E        T R G R  +R+R++ + R       R+ +R     ++
Sbjct: 337 REKERERKRKRQTEMDRERNRQTGREGRRQAERERERERER------DRQSAREREERER 390

Query: 239 QRAQDREEEAAAAPAPTSSGHR-TEKRK 265
            R +DR++E          G R TEK++
Sbjct: 391 DRDRDRQKERERQTEKDRDGQRETEKQR 418



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 54/264 (20%), Positives = 96/264 (36%), Gaps = 16/264 (6%)

Query: 2   KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQ 61
           + R+KE  T  R      E ++  E E     + Q   +      T + R       A++
Sbjct: 193 RQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERER----EKQAER 248

Query: 62  QGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQR 121
           + A +RE E       ++ R +DR+         T    +    + ++ + +      + 
Sbjct: 249 ERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERE 308

Query: 122 RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSP 181
           R    +   +++  ++RE E            R  KRK Q    R       R G R   
Sbjct: 309 RERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRR--- 365

Query: 182 SADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRA 241
            A+++  ++RE +  +A     R  R   R R + + R       R G R +    ++R 
Sbjct: 366 QAERERERERERDRQSA---REREERERDRDRDRQKERERQTEKDRDGQRET-EKQRERE 421

Query: 242 QDREEEAAAAPAPTSSGHRTEKRK 265
           +DRE E          G   EK+K
Sbjct: 422 KDRESERG-----RERGREREKQK 440



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 50/249 (20%), Positives = 94/249 (37%), Gaps = 24/249 (9%)

Query: 2   KPRQKEQDTR--LRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSA 59
           +P  +E   R  L +  + ++GD    N + +  R +++ Q +                 
Sbjct: 30  RPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTER--------------ET 75

Query: 60  DQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTG 119
           D++  + RE++        ++R +DRE+E            R ++R  Q+ + R     G
Sbjct: 76  DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135

Query: 120 QRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRS 179
           +R   G     D Q  ++R+ +A       +   R  + +  + + R      Q R  R 
Sbjct: 136 ER---GRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERE 192

Query: 180 SPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRS-SPSADQ 238
                +   +DR  E               +RKRQ  + R      QR+  R     A++
Sbjct: 193 RQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR----QRKTEREREKQAER 248

Query: 239 QRAQDREEE 247
           +RA +RE E
Sbjct: 249 ERASERETE 257



 Score = 35.8 bits (81), Expect = 0.040
 Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 6/131 (4%)

Query: 121 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRS- 179
           RR  GS  S  ++G     ++A       +R    E+R+ ++   R      +RR  +  
Sbjct: 28  RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87

Query: 180 --SPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSAD 237
                  ++  +DRE+E            R ++R RQ+ + R     G+R   R +   D
Sbjct: 88  HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQT---D 144

Query: 238 QQRAQDREEEA 248
            QR ++R+ +A
Sbjct: 145 GQRERERQRDA 155



 Score = 31.6 bits (70), Expect = 0.75
 Identities = 25/145 (17%), Positives = 52/145 (35%), Gaps = 5/145 (3%)

Query: 104 KRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQP 163
           +R+P   +     G GQ          ++   ++RE              + E+R+ +  
Sbjct: 28  RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87

Query: 164 QRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAG 223
            R+      + R  +     +++   DRE +         +  R  + +R+  + R    
Sbjct: 88  HRK----RDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQT 143

Query: 224 TGQRRGSRS-SPSADQQRAQDREEE 247
            GQR   R      +++R  DRE +
Sbjct: 144 DGQRERERQRDAEKERERQTDRERQ 168



 Score = 30.4 bits (67), Expect = 1.7
 Identities = 40/183 (21%), Positives = 73/183 (39%), Gaps = 24/183 (13%)

Query: 2   KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQ--------QPQCQPAGGTGQRRGS 53
           + R++E+D +  + RE  E D+  + +K +  + ++        + Q +        RG 
Sbjct: 371 RERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGR 430

Query: 54  GSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCR 113
                 ++Q  ++R+ E      A +QR   +       P P ++     +  P     R
Sbjct: 431 ERGREREKQKGRERDRERQTDRQAGRQR---KRSTLYVNPPPRTARSGVVQSDPN----R 483

Query: 114 PAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRK--PQQPQRRPAAGT 171
           P  G   +    SSP  D + A  R       PA  SRG    +R+  P+  ++R   G 
Sbjct: 484 PTRGIRWK----SSPE-DPKAASTR--FPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGE 536

Query: 172 GQR 174
           G+R
Sbjct: 537 GRR 539


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 56/248 (22%), Positives = 97/248 (39%), Gaps = 42/248 (16%)

Query: 46  GTGQRRGSGSSPSADQQGAQDREEEA----AAAPAADQQRAQDREEEAAAAPAPTSSGHR 101
           GT +R     +P   +    + EE+     AAA +  Q+R   R+ + +++ + +SS   
Sbjct: 444 GTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSE 503

Query: 102 TEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEA------------------A 143
            E+ K    +    G  G+RR    S SA     + ++E +                  +
Sbjct: 504 DERPKRSHVK---NGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS 560

Query: 144 AAPAPTSRGHRT-----EKRKPQQPQRRPAAGTG------QRRGSRSSPSADQQGAQDRE 192
            +PAP  R  RT      +R P  P RR +          QRR S S P   +  +    
Sbjct: 561 PSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP 620

Query: 193 EEAAAAPVPTSR---GHRTEKRKRQQPQCR---PAAGTGQRRGSRSSPSADQQRAQDREE 246
            +  A+P P  +    H    ++R  P  +   P+  +  R+GS  S S  + R+    +
Sbjct: 621 PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNK 680

Query: 247 EAAAAPAP 254
             + +P P
Sbjct: 681 RHSPSPRP 688



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 54/291 (18%), Positives = 120/291 (41%), Gaps = 31/291 (10%)

Query: 3   PRQKEQDTRLRK--LRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60
           P   E   ++++  ++E++     L+  K +P+   ++P   P   + + +    +    
Sbjct: 221 PELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPS--PEKNSKKEKEKEKTRPRS 278

Query: 61  QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTE--------KRKPQQPQC 112
           +  ++ R    + +P+  + R + R    + +P    S  R          +R P  P+ 
Sbjct: 279 RSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRH 338

Query: 113 RPAGGTGQRR--------GSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 164
           R +    +RR        GS SS S+ +  +  ++     +  P      +    P + +
Sbjct: 339 RRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRR 398

Query: 165 RRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTS----RGHRTEKRKRQQPQCRP 220
            RP+        +R SP+  QQ  + R+   + +P  TS    +   TEKR+   P  +P
Sbjct: 399 HRPSPPATPPPKTRHSPT-PQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457

Query: 221 ----AAGTGQRRGSR--SSPSADQQRAQDREEEAAAAPAPTSSGHRTEKRK 265
                + + + +G +  ++ S  Q+R   R+ + +++ + +SS    E+ K
Sbjct: 458 RKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPK 508



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 45/216 (20%), Positives = 76/216 (35%), Gaps = 23/216 (10%)

Query: 49  QRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQ 108
           +RR S S P   +     +    + +    +  +  R    A +P P      +   +P+
Sbjct: 632 KRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNK--RHSPSPRPR 689

Query: 109 QPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPA 168
            PQ   +     RRG+ SSP   Q            +P+P++R  R   R P+  + + A
Sbjct: 690 APQTS-SSPPPVRRGASSSPQRRQ------------SPSPSTRPIRRVSRTPEPKKIKKA 736

Query: 169 AGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRR 228
           A    +   R S S    G+   E  A   P P S        + Q P    +     ++
Sbjct: 737 ASPSPQSVRRVSSSRSVSGSP--EPAAKKPPAPPS------PVQSQSPSTNWSPAVPVKK 788

Query: 229 GSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKR 264
               +PS    R  D+E             H+ +K+
Sbjct: 789 AKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKK 824



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 40/226 (17%), Positives = 79/226 (34%), Gaps = 14/226 (6%)

Query: 49  QRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQ 108
           +RR S S   +    +  R       P         +    + + +P    HR       
Sbjct: 348 RRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATP 407

Query: 109 QPQCR------PAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ 162
            P+ R       +  T + R S S      +  + +  E   +P+P  +  + E  + ++
Sbjct: 408 PPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEE 467

Query: 163 PQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGH----RTEKRKRQQPQC 218
            +    A     +  R     +QQ + D    +++      R H       +R+R  P  
Sbjct: 468 DKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS- 526

Query: 219 RPAAGTGQRRGSRSSPSADQQRAQD---REEEAAAAPAPTSSGHRT 261
           R A+ + ++R   +SP   ++R+          + +PAP     RT
Sbjct: 527 RSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRT 572



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 38/237 (16%), Positives = 86/237 (36%), Gaps = 21/237 (8%)

Query: 28  EKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREE 87
           +++ P+  ++ P          +   GSSPS   + A+  +     +P+      + R  
Sbjct: 643 QRSSPVTKRRSPSLS------SKHRKGSSPSRSTREARSPQPNKRHSPSP-----RPRAP 691

Query: 88  EAAAAPAPTSSGHRT--EKRKPQQPQCRPAGGTGQ-------RRGSGSSPSADQQGAQDR 138
           + +++P P   G  +  ++R+   P  RP     +       ++ +  SP + ++ +  R
Sbjct: 692 QTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSR 751

Query: 139 EEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAA 198
               +  PA           + Q P    +     ++    +PS       D+E      
Sbjct: 752 SVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKK 811

Query: 199 PVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQD-REEEAAAAPAP 254
                + H+ +K+ ++  + +          +  +P+A         +EE  AAP P
Sbjct: 812 KKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEP 868



 Score = 30.4 bits (67), Expect = 1.7
 Identities = 30/161 (18%), Positives = 60/161 (37%), Gaps = 24/161 (14%)

Query: 120 QRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRS 179
           ++  S      D+      E+E++      SR  R  K +   P+RR +    +R+ S S
Sbjct: 139 EKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHS 198

Query: 180 ------SPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQ------- 226
                 + S     A +++E+    P P+         K ++P  + A  T         
Sbjct: 199 RSPRHRTKSRSPSPAPEKKEKTPELPEPSV--------KVKEPSVQEATSTSDILKVPKP 250

Query: 227 ---RRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKR 264
                    SP  + ++ +++E+    + + + S  RT  R
Sbjct: 251 EPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSR 291


>gi|71274172 ankyrin repeat domain 56 [Homo sapiens]
          Length = 793

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 65/243 (26%), Positives = 84/243 (34%), Gaps = 57/243 (23%)

Query: 34  RPQQQPQCQPAGG-------TGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDRE 86
           RP++ P   P+ G        G RRG    P   Q   + RE+E    PA    RA D  
Sbjct: 88  RPREPPAAAPSAGGAAPCSPRGARRGE---PPQQQPRRRRREKEPEEEPAGAAARAAD-- 142

Query: 87  EEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSP---SADQQGAQDREEEAA 143
             AA    P S   R            P  G G +   G  P   +A   GAQ R   AA
Sbjct: 143 --AACNGLPGSDSRRA-----------PGKGGGSKGSPGQRPPVPAAAAAGAQARASCAA 189

Query: 144 AAPAPTSRGHRTEKR---KPQQPQRRPAAGTGQRRGSRSSPSADQQGA-QDREEEAAAAP 199
           A           +      P +    P + T + + +R+ P+ D +GA ++REE A A P
Sbjct: 190 AKTQGRCCWECLQNNLAVLPGELGALPHSATAEEKPARALPAQDDRGASREREEGALAEP 249

Query: 200 VPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGH 259
            P                  PA           SP A  + A  R    A  P P   G 
Sbjct: 250 APV-----------------PAVA--------HSPPATVEAATSRASPPALLPGPAPRGD 284

Query: 260 RTE 262
           R E
Sbjct: 285 RPE 287


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 59/239 (24%), Positives = 90/239 (37%), Gaps = 33/239 (13%)

Query: 46  GTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKR 105
           G  Q  G+G  P AD          AAAA AA    AQ R   A  +P  +  G +   R
Sbjct: 318 GGPQDGGAGKGP-ADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLAR 376

Query: 106 KPQQPQCRPAGGTGQRRG---SGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ 162
            PQ     P    G+ R     G++P + QQG     ++    P     G +T +R P  
Sbjct: 377 TPQPSS--PMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPG-QPYGSQTPQRYPMT 433

Query: 163 PQRRPAAGTGQRRGSRSSPSADQQG-----------------AQDREEEAAAAPVPTSRG 205
            Q R  +  G    ++  P   QQG                    ++++   +  P S+ 
Sbjct: 434 MQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQT 493

Query: 206 HRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKR 264
              +   +QQPQ +P       +   S P   QQ +Q   ++   +PAP  S   T ++
Sbjct: 494 PHAQPSYQQQPQSQPP------QLQSSQPPYSQQPSQPPHQQ---SPAPYPSQQSTTQQ 543



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 53/230 (23%), Positives = 90/230 (39%), Gaps = 25/230 (10%)

Query: 28  EKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG-AQDREEEAAAAPAADQQRAQDRE 86
           + + P+    + + QP GGT         PS  QQG     +   +  P       Q R 
Sbjct: 379 QPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA 438

Query: 87  EEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAP 146
           + A    + T       ++ P   Q  P+ G GQ+   G +P  +QQ    ++++   + 
Sbjct: 439 QSAMGGLSYT-------QQIPPYGQQGPS-GYGQQ---GQTPYYNQQSPHPQQQQPPYSQ 487

Query: 147 APTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGH 206
            P S+    +    QQPQ +P       +   S P   QQ +Q   ++ + AP P+ +  
Sbjct: 488 QPPSQTPHAQPSYQQQPQSQPP------QLQSSQPPYSQQPSQPPHQQ-SPAPYPSQQST 540

Query: 207 RTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTS 256
             +  + Q P  +P A +  ++         QQ A     + AA P P S
Sbjct: 541 TQQHPQSQPPYSQPQAQSPYQQ------QQPQQPAPSTLSQQAAYPQPQS 584



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 41/169 (24%), Positives = 65/169 (38%), Gaps = 24/169 (14%)

Query: 35  PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPA 94
           P  Q Q  P       +   + PS  QQ      +  ++ P   QQ +Q   +++   PA
Sbjct: 476 PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQS---PA 532

Query: 95  PTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHR 154
           P  S   T +   Q PQ +P             P +  Q     +++    PAP++   +
Sbjct: 533 PYPSQQSTTQ---QHPQSQP-------------PYSQPQAQSPYQQQQPQQPAPSTLSQQ 576

Query: 155 TEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTS 203
               +PQ  Q +  A + QR       S D  G+Q     A++AP  TS
Sbjct: 577 AAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQ-----ASSAPSMTS 620



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 55/205 (26%), Positives = 69/205 (33%), Gaps = 30/205 (14%)

Query: 59  ADQQGAQDREEEAAAAPAADQ---QRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPA 115
           A+QQ  ++   EAAAA AA++   + A  +E E  A   P   G   +            
Sbjct: 27  AEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESN-----G 81

Query: 116 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRR 175
           GG G   GSG  P A+      +     A P P    + TE          P  G G   
Sbjct: 82  GGGGGGAGSGGGPGAE---PDLKNSNGNAGPRPALNNNLTEP---------PGGGGG--- 126

Query: 176 GSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPS 235
           GS     A    A      AAA P P     +   R         AA   Q+ G + SP 
Sbjct: 127 GSSDGVGAPPHSA------AAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180

Query: 236 -ADQQRAQDREEEAAAAPAPTSSGH 259
            A  Q       E  A P   S  H
Sbjct: 181 LAALQSGGGGGLEPYAGPQQNSHDH 205



 Score = 28.1 bits (61), Expect = 8.3
 Identities = 43/172 (25%), Positives = 58/172 (33%), Gaps = 34/172 (19%)

Query: 89  AAAAPAPTSSGHR------TEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEA 142
           A  APA  SS         +E +K +Q Q   AG  G+   + ++   + + A  +E E 
Sbjct: 3   AQVAPAAASSLGNPPPPPPSELKKAEQQQREEAG--GEAAAAAAAERGEMKAAAGQESEG 60

Query: 143 AAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPT 202
            A   P   G     ++ Q        G G   GS   P A+      +     A P P 
Sbjct: 61  PAVGPPQPLG-----KELQDGAESNGGGGGGGAGSGGGPGAE---PDLKNSNGNAGPRPA 112

Query: 203 SRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAP 254
              + TE          P  G G   GS     A    A      AAA P P
Sbjct: 113 LNNNLTEP---------PGGGGG---GSSDGVGAPPHSA------AAALPPP 146


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 59/239 (24%), Positives = 90/239 (37%), Gaps = 33/239 (13%)

Query: 46  GTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKR 105
           G  Q  G+G  P AD          AAAA AA    AQ R   A  +P  +  G +   R
Sbjct: 318 GGPQDGGAGKGP-ADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLAR 376

Query: 106 KPQQPQCRPAGGTGQRRG---SGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ 162
            PQ     P    G+ R     G++P + QQG     ++    P     G +T +R P  
Sbjct: 377 TPQPSS--PMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPG-QPYGSQTPQRYPMT 433

Query: 163 PQRRPAAGTGQRRGSRSSPSADQQG-----------------AQDREEEAAAAPVPTSRG 205
            Q R  +  G    ++  P   QQG                    ++++   +  P S+ 
Sbjct: 434 MQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQT 493

Query: 206 HRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKR 264
              +   +QQPQ +P       +   S P   QQ +Q   ++   +PAP  S   T ++
Sbjct: 494 PHAQPSYQQQPQSQPP------QLQSSQPPYSQQPSQPPHQQ---SPAPYPSQQSTTQQ 543



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 53/230 (23%), Positives = 90/230 (39%), Gaps = 25/230 (10%)

Query: 28  EKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG-AQDREEEAAAAPAADQQRAQDRE 86
           + + P+    + + QP GGT         PS  QQG     +   +  P       Q R 
Sbjct: 379 QPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA 438

Query: 87  EEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAP 146
           + A    + T       ++ P   Q  P+ G GQ+   G +P  +QQ    ++++   + 
Sbjct: 439 QSAMGGLSYT-------QQIPPYGQQGPS-GYGQQ---GQTPYYNQQSPHPQQQQPPYSQ 487

Query: 147 APTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGH 206
            P S+    +    QQPQ +P       +   S P   QQ +Q   ++ + AP P+ +  
Sbjct: 488 QPPSQTPHAQPSYQQQPQSQPP------QLQSSQPPYSQQPSQPPHQQ-SPAPYPSQQST 540

Query: 207 RTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTS 256
             +  + Q P  +P A +  ++         QQ A     + AA P P S
Sbjct: 541 TQQHPQSQPPYSQPQAQSPYQQ------QQPQQPAPSTLSQQAAYPQPQS 584



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 41/169 (24%), Positives = 65/169 (38%), Gaps = 24/169 (14%)

Query: 35  PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPA 94
           P  Q Q  P       +   + PS  QQ      +  ++ P   QQ +Q   +++   PA
Sbjct: 476 PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQS---PA 532

Query: 95  PTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHR 154
           P  S   T +   Q PQ +P             P +  Q     +++    PAP++   +
Sbjct: 533 PYPSQQSTTQ---QHPQSQP-------------PYSQPQAQSPYQQQQPQQPAPSTLSQQ 576

Query: 155 TEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTS 203
               +PQ  Q +  A + QR       S D  G+Q     A++AP  TS
Sbjct: 577 AAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQ-----ASSAPSMTS 620



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 55/205 (26%), Positives = 69/205 (33%), Gaps = 30/205 (14%)

Query: 59  ADQQGAQDREEEAAAAPAADQ---QRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPA 115
           A+QQ  ++   EAAAA AA++   + A  +E E  A   P   G   +            
Sbjct: 27  AEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESN-----G 81

Query: 116 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRR 175
           GG G   GSG  P A+      +     A P P    + TE          P  G G   
Sbjct: 82  GGGGGGAGSGGGPGAE---PDLKNSNGNAGPRPALNNNLTEP---------PGGGGG--- 126

Query: 176 GSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPS 235
           GS     A    A      AAA P P     +   R         AA   Q+ G + SP 
Sbjct: 127 GSSDGVGAPPHSA------AAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180

Query: 236 -ADQQRAQDREEEAAAAPAPTSSGH 259
            A  Q       E  A P   S  H
Sbjct: 181 LAALQSGGGGGLEPYAGPQQNSHDH 205



 Score = 28.1 bits (61), Expect = 8.3
 Identities = 43/172 (25%), Positives = 58/172 (33%), Gaps = 34/172 (19%)

Query: 89  AAAAPAPTSSGHR------TEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEA 142
           A  APA  SS         +E +K +Q Q   AG  G+   + ++   + + A  +E E 
Sbjct: 3   AQVAPAAASSLGNPPPPPPSELKKAEQQQREEAG--GEAAAAAAAERGEMKAAAGQESEG 60

Query: 143 AAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPT 202
            A   P   G     ++ Q        G G   GS   P A+      +     A P P 
Sbjct: 61  PAVGPPQPLG-----KELQDGAESNGGGGGGGAGSGGGPGAE---PDLKNSNGNAGPRPA 112

Query: 203 SRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAP 254
              + TE          P  G G   GS     A    A      AAA P P
Sbjct: 113 LNNNLTEP---------PGGGGG---GSSDGVGAPPHSA------AAALPPP 146


>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
          Length = 1007

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 53/255 (20%), Positives = 113/255 (44%), Gaps = 15/255 (5%)

Query: 2   KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQ-PAGGTGQRRGSGSSPSAD 60
           K R KE+ TR R  ++ S+G   +  EKT   + +++ + + P+  +  +  +  S S  
Sbjct: 185 KSRSKER-TRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPT 243

Query: 61  QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ 120
            +     +   A +P  D+ + +D+ +      +P  +  R+  R  +        G  +
Sbjct: 244 LRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSK 303

Query: 121 RRGSGSSPSADQQGAQDREEEAAAAP---APTSRGHRTEKRKPQQPQRRPAAGTGQRRGS 177
            R S S     ++   D+E++   +P   A + + +R+  R+P +  +R +     R  S
Sbjct: 304 DRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKS 363

Query: 178 RSSPSA---DQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSP 234
           R S S    D++  Q +      +P   ++  R+ +RKR++P+ R      +    R+ P
Sbjct: 364 RRSRSPLLNDRRSKQSKSPSRTLSPGRRAKS-RSLERKRREPERR------RLSSPRTRP 416

Query: 235 SADQQRAQDREEEAA 249
             D    ++R ++A+
Sbjct: 417 RDDILSRRERSKDAS 431



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 41/191 (21%), Positives = 81/191 (42%), Gaps = 16/191 (8%)

Query: 81  RAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREE 140
           R++ +E + + +P+  S   + + RK + P  R    + ++ G   SP+ D+   +D+ +
Sbjct: 214 RSKSKERKKSKSPSKRSKS-QDQARKSKSPTLRRR--SQEKIGKARSPTDDKVKIEDKSK 270

Query: 141 EAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPV 200
                 +P     R+  R  +        G  + R SRS     ++   D+E++    P+
Sbjct: 271 SKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKK----PI 326

Query: 201 PTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR------AQDREEEAAAAPAP 254
            +     +  ++ + P  RP  G   +R S S    D+ R        DR  + + +P+ 
Sbjct: 327 KSPSKDASSGKENRSPSRRP--GRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSR 384

Query: 255 T-SSGHRTEKR 264
           T S G R + R
Sbjct: 385 TLSPGRRAKSR 395



 Score = 34.7 bits (78), Expect = 0.088
 Identities = 49/216 (22%), Positives = 78/216 (36%), Gaps = 45/216 (20%)

Query: 4   RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG 63
           R K +D R R     S+      +E  K  +P + P    + G   R     SPS  + G
Sbjct: 299 RGKSKDRRSRSKERKSK-----RSETDKEKKPIKSPSKDASSGKENR-----SPSR-RPG 347

Query: 64  AQDREEEAAAAPAADQQRAQ-----DREEEAAAAPAPT-SSGHRT------------EKR 105
              +    +  P    +R++     DR  + + +P+ T S G R             E+R
Sbjct: 348 RSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERR 407

Query: 106 KPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAA------APAPTSRGHRTEKRK 159
           +   P+ RP      RR      S   + +  R    +       +P   SR  R   R 
Sbjct: 408 RLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRS 467

Query: 160 PQQP----------QRRPAAGTGQRRGSRSSPSADQ 185
           P++           +RR  +  G+RR SRS    D+
Sbjct: 468 PRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDK 503


>gi|239750916 PREDICTED: similar to hCG1803335 [Homo sapiens]
          Length = 246

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 50/215 (23%), Positives = 78/215 (36%), Gaps = 26/215 (12%)

Query: 58  SADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQ-----QPQC 112
           S  Q+ A+  E            R   R  E+   P     GHR   R  +     Q QC
Sbjct: 38  SLHQRSARATESVPGPQSQCQGHRVSSRATESVPGPQSQFQGHRVSARATESVPGPQSQC 97

Query: 113 RPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSR--GHRTEKRKPQQ---PQRRP 167
           +    + +   S   P + +QG +       +AP P S+  GHR   R  +    PQ   
Sbjct: 98  QGHRVSSRATESVPGPQSQRQGHRVSARATESAPGPQSQCQGHRVSARATESVPGPQ--- 154

Query: 168 AAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQR 227
                QR+G R S          R  E+A  P    +GHR   R  +      +   G R
Sbjct: 155 ----SQRQGHRVS---------SRATESAPGPQSQFQGHRVSARATESVPGPQSQRQGHR 201

Query: 228 RGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTE 262
             SR++ S    ++Q +    +A    +  G +++
Sbjct: 202 VSSRATESVPGPQSQFQGHRVSARATESVPGPQSQ 236



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 45/187 (24%), Positives = 67/187 (35%), Gaps = 20/187 (10%)

Query: 98  SGHRTEKRKPQQPQCRPAGGTGQRRGSGSS----PSADQQGAQDREEEAAAAPAPTSR-- 151
           S H +   +  +PQ +      QR    +     P +  QG +       + P P S+  
Sbjct: 19  SCHHSWHPQTPKPQIKAHDSLHQRSARATESVPGPQSQCQGHRVSSRATESVPGPQSQFQ 78

Query: 152 GHRTEKRKPQQPQRRPAAGTGQRRGSRSS-----PSADQQG--AQDREEEAAAAPVPTSR 204
           GHR   R  +      +   G R  SR++     P + +QG     R  E+A  P    +
Sbjct: 79  GHRVSARATESVPGPQSQCQGHRVSSRATESVPGPQSQRQGHRVSARATESAPGPQSQCQ 138

Query: 205 GHRTEKRKRQQ---PQCRPAAGTGQRRGSRSSPSADQQ----RAQDREEEAAAAPAPTSS 257
           GHR   R  +    PQ +        R + S+P    Q    R   R  E+   P     
Sbjct: 139 GHRVSARATESVPGPQSQRQGHRVSSRATESAPGPQSQFQGHRVSARATESVPGPQSQRQ 198

Query: 258 GHRTEKR 264
           GHR   R
Sbjct: 199 GHRVSSR 205



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 35/135 (25%), Positives = 50/135 (37%), Gaps = 11/135 (8%)

Query: 35  PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQ----RAQDREEEAA 90
           P  Q QCQ    + +   S   P + +QG +       +AP    Q    R   R  E+ 
Sbjct: 91  PGPQSQCQGHRVSSRATESVPGPQSQRQGHRVSARATESAPGPQSQCQGHRVSARATESV 150

Query: 91  AAPAPTSSGHRTEKRKPQQ---PQCRPAGGTGQRRGSGS--SPSADQQGAQDREEEAAAA 145
             P     GHR   R  +    PQ +  G     R + S   P + +QG +       + 
Sbjct: 151 PGPQSQRQGHRVSSRATESAPGPQSQFQGHRVSARATESVPGPQSQRQGHRVSSRATESV 210

Query: 146 PAPTS--RGHRTEKR 158
           P P S  +GHR   R
Sbjct: 211 PGPQSQFQGHRVSAR 225



 Score = 35.0 bits (79), Expect = 0.068
 Identities = 32/124 (25%), Positives = 45/124 (36%), Gaps = 11/124 (8%)

Query: 39  PQCQPAGGTGQRRGSGSSPSADQQ----GAQDREEEAAAAPAADQQ--RAQDREEEAAAA 92
           PQ Q  G     R + S+P    Q        R  E+   P + +Q  R   R  E+A  
Sbjct: 113 PQSQRQGHRVSARATESAPGPQSQCQGHRVSARATESVPGPQSQRQGHRVSSRATESAPG 172

Query: 93  PAPTSSGHRTEKRKPQQ---PQCRPAGGTGQRRGSGS--SPSADQQGAQDREEEAAAAPA 147
           P     GHR   R  +    PQ +  G     R + S   P +  QG +       + P 
Sbjct: 173 PQSQFQGHRVSARATESVPGPQSQRQGHRVSSRATESVPGPQSQFQGHRVSARATESVPG 232

Query: 148 PTSR 151
           P S+
Sbjct: 233 PQSQ 236



 Score = 34.7 bits (78), Expect = 0.088
 Identities = 29/106 (27%), Positives = 39/106 (36%), Gaps = 7/106 (6%)

Query: 35  PQQQPQCQPAGGTGQRRGSGSSPSADQQG--AQDREEEAAAAPAADQQ--RAQDREEEAA 90
           P  Q QCQ    + +   S   P + +QG     R  E+A  P +  Q  R   R  E+ 
Sbjct: 131 PGPQSQCQGHRVSARATESVPGPQSQRQGHRVSSRATESAPGPQSQFQGHRVSARATESV 190

Query: 91  AAPAPTSSGHRTEKRKPQQ---PQCRPAGGTGQRRGSGSSPSADQQ 133
             P     GHR   R  +    PQ +  G     R + S P    Q
Sbjct: 191 PGPQSQRQGHRVSSRATESVPGPQSQFQGHRVSARATESVPGPQSQ 236


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 58/261 (22%), Positives = 99/261 (37%), Gaps = 24/261 (9%)

Query: 13  RKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAA 72
           +KL  S    +     KT           + +  +    GSGSS S  +  +       +
Sbjct: 527 KKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRS 586

Query: 73  AAPAA-DQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSAD 131
           +  ++    R++ R   ++ +P+PT S HR   R   +P   P G  G++     +P   
Sbjct: 587 SRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEP-APPPGKAGEKSVKKPAPPPA 645

Query: 132 QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ-----PQRRPAAGTGQRRGSRSSPSADQQ 186
              A    +  A  P PT  G   E R+ ++     P+RR  +G+G   GS  S S+ + 
Sbjct: 646 PPQA---TKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRS 702

Query: 187 G--AQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDR 244
              +       ++A   +S  H  +          P +    R     SP+     AQ R
Sbjct: 703 RSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSR-----SPAP----AQTR 753

Query: 245 EEEAAAAPAPTSSGHRTEKRK 265
           +E+     +    G + EKRK
Sbjct: 754 KEK---GKSKKEDGVKEEKRK 771



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 52/268 (19%), Positives = 107/268 (39%), Gaps = 16/268 (5%)

Query: 4   RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG 63
           RQ+E++    + RE     +  E E+      ++Q + +       +R        D+  
Sbjct: 413 RQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDR 472

Query: 64  AQDREEEAAA----APAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTG 119
            ++RE+E       +P    ++A+  ++EAA      ++G + ++    +   R +    
Sbjct: 473 EKEREKEKGKPKPRSPQPPSRQAEPPKKEAA------TTGPQVKRADEWKDPWRRSKSPK 526

Query: 120 QRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRS 179
           ++ G   SPS  ++  +     A+A+ +  S    +        + R  + +     SRS
Sbjct: 527 KKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRS 586

Query: 180 SPSADQQGAQDREE--EAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSAD 237
           S  +   G++ R     ++ +P PT   HR   R + +P   P    G++   + +P   
Sbjct: 587 SRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEP-APPPGKAGEKSVKKPAPPPA 645

Query: 238 QQRAQDREEEAAAAPAPTSSGHRTEKRK 265
             +A    +  A  P PT  G   E R+
Sbjct: 646 PPQA---TKTTAPVPEPTKPGDPREARR 670



 Score = 32.0 bits (71), Expect = 0.57
 Identities = 31/140 (22%), Positives = 59/140 (42%), Gaps = 14/140 (10%)

Query: 57  PSADQQGAQDREEEAAAAPAADQQRAQDREEEA-AAAPAPTSSGHRTEKRKPQQPQCRPA 115
           PS +++     EE+ A+ P     ++QD++ E    +  PTSS    E  + ++ +    
Sbjct: 58  PSQEEEDNHSDEEDRASEP-----KSQDQDSEVNELSRGPTSSPCEEEGDEGEEDR---- 108

Query: 116 GGTGQRRGSGSSPSAD-QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQR 174
             T   R   SS + +  +   D +EE    PAP  +    EK   +  + +   GT + 
Sbjct: 109 --TSDLRDEASSVTRELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEK-GEGTPRE 165

Query: 175 RGSRSSPSADQQGAQDREEE 194
            G     S  ++ + +  +E
Sbjct: 166 EGKAGVQSVGEKESLEAAKE 185



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 29/130 (22%), Positives = 51/130 (39%), Gaps = 9/130 (6%)

Query: 18  SSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQ--QGAQDR----EEEA 71
           S E +    +E+ +   P+ Q Q          RG  SSP  ++  +G +DR     +EA
Sbjct: 59  SQEEEDNHSDEEDRASEPKSQDQDSEVNELS--RGPTSSPCEEEGDEGEEDRTSDLRDEA 116

Query: 72  AAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSAD 131
           ++      +   D +EE    PAP       EK   +  +     GT +  G     S  
Sbjct: 117 SSVTRELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDE-EKGEGTPREEGKAGVQSVG 175

Query: 132 QQGAQDREEE 141
           ++ + +  +E
Sbjct: 176 EKESLEAAKE 185



 Score = 28.5 bits (62), Expect = 6.3
 Identities = 30/154 (19%), Positives = 59/154 (38%), Gaps = 18/154 (11%)

Query: 120 QRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRS 179
           +R         +++  +DRE E         R H  E+ K +Q ++        +R  + 
Sbjct: 407 ERERENRQRERERERERDRERERRQREREREREH--ERDKERQRRKEEWERERAKRDEKD 464

Query: 180 SPSADQQGAQDREEEAA----AAPVPTSR------------GHRTEKRKRQQPQCRPAAG 223
               D+   ++RE+E       +P P SR            G + ++    +   R +  
Sbjct: 465 RQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKS 524

Query: 224 TGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSS 257
             ++ G   SPS  ++R +     A+A+ +  SS
Sbjct: 525 PKKKLGVSVSPSRARRRRKTSASSASASNSSRSS 558


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 50/242 (20%), Positives = 97/242 (40%), Gaps = 18/242 (7%)

Query: 16  RESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAP 75
           ++   G    E E T    P ++ +   +    +++    S    ++   D EE+++ A 
Sbjct: 644 KQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAE 703

Query: 76  AADQ---QRAQDREEEAAAAPAPTSSGHRTEKRKPQQP----QCRPAGGTGQRRGSGSSP 128
           + ++   ++ + R++  ++APA +  G + E      P    + R A    QRR   S P
Sbjct: 704 SGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRR---SLP 760

Query: 129 SADQQGAQDREEEAAAAPAPTSRGHRTEKRK--PQQPQRRPAAGTGQRRGSRSSPSADQQ 186
           +  ++G+  +++E     +    G R  K +  P   QRR       R   RS PS+  +
Sbjct: 761 A--EEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDE 818

Query: 187 GAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQR----RGSRSSPSADQQRAQ 242
            + D          P+      E+        R  + +G+R    R SR S S+    + 
Sbjct: 819 DSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASS 878

Query: 243 DR 244
           D+
Sbjct: 879 DQ 880



 Score = 32.7 bits (73), Expect = 0.34
 Identities = 36/164 (21%), Positives = 68/164 (41%), Gaps = 30/164 (18%)

Query: 113 RPAGGTGQRRGSGSSPSA----DQQGAQDREEEAAAAPAPTSR-----GHRTEKRKPQQP 163
           R +GG      SGS+ S     +  G+   E E      P+ +      HR +K+K  + 
Sbjct: 624 RSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKK 683

Query: 164 ----QRRPAAGTGQRRG-SRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQC 218
               +R+  A T ++   + S   + ++  + R++  ++AP  + RG + E         
Sbjct: 684 SSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEP-------- 735

Query: 219 RPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTE 262
            P +G+        +P   ++RAQD  +  +      SSG + E
Sbjct: 736 -PGSGS-------PAPPRRRRRAQDDSQRRSLPAEEGSSGKKDE 771


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 55/265 (20%), Positives = 94/265 (35%), Gaps = 13/265 (4%)

Query: 3   PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
           PR  ++D         S       + +T           Q     G+R GSG   SAD  
Sbjct: 336 PRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSS 395

Query: 63  GAQDREEEAAAAPAADQ-------QRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPA 115
                    A++  +D+        +A D E  +  +   + SGH     + Q  Q    
Sbjct: 396 RHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTR 455

Query: 116 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHR--TEKRKPQQPQRRPAAGTGQ 173
           G +G+R  SG S S+  Q +   + ++A     TS G R  +   + +   R  A+  GQ
Sbjct: 456 GRSGER--SGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQ 513

Query: 174 R--RGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSR 231
              RG   S    +QG+   +    +    +   H T + +      +  + +  R+   
Sbjct: 514 DTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRN 573

Query: 232 SSPSADQQRAQDREEEAAAAPAPTS 256
              S D  R        A++ A +S
Sbjct: 574 EEQSGDGTRHSGSRHHEASSQADSS 598



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 59/238 (24%), Positives = 89/238 (37%), Gaps = 38/238 (15%)

Query: 43   PAGGTGQRRGSGSSPSADQQG----------AQDREEEAAAAPAADQQRAQDREEEAAAA 92
            P      R+GS    S D+ G          +Q R + +     +     Q R +E +  
Sbjct: 3438 PGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGD 3497

Query: 93   PAPTSSGHRTE-------KRKPQQPQCRPAGG-TGQRRGSGSSPSADQQG-AQDREEEAA 143
             +  S  H  E        R  Q  Q + AG  T + +GS  S  +D QG ++D E  + 
Sbjct: 3498 GSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSG 3557

Query: 144  AAPAPTSRGHR-TEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPT 202
            +A    SR HR + + + +   R P +    R G   S  + +Q      E ++     +
Sbjct: 3558 SA----SRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAAS 3613

Query: 203  SRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHR 260
            S             Q R +A  G+R GS    SAD  R         A+ A   SGHR
Sbjct: 3614 S-----------HEQARSSA--GERHGSHHQQSADSSR-HSGIGHGQASSAVRDSGHR 3657



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 59/264 (22%), Positives = 96/264 (36%), Gaps = 35/264 (13%)

Query: 15   LRESSEGDQWLENEKTKPLRPQQQP-QCQPAGGTGQRRGSGSSPSADQQG---------- 63
            +R+ S  +Q  +N +    +  Q   +  P      R+GS    S D+ G          
Sbjct: 816  VRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTT 875

Query: 64   AQDREEEAAAAPAADQQRAQDREEEAAAAPAPTS-------SGHRTEKRKPQQPQCRPAG 116
            +Q R + +     +       R EE +   +  S       S H    R  Q  Q +  G
Sbjct: 876  SQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEG 935

Query: 117  G-TGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRR 175
              T +R+GS  S  +D +G  +  E  + + +   RG   E+ +     R P +    R 
Sbjct: 936  SRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSR--HGSRHPRSHHEDRA 993

Query: 176  GSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPS 235
            G   S  + +Q      E ++     +S      ++ R  P        G+R GSR   S
Sbjct: 994  GHGHSADSSRQSGTPHAETSSGGQAASSH-----EQARSSP--------GERHGSRHQQS 1040

Query: 236  ADQQRAQDREEEAAAAPAPTSSGH 259
            AD  R        A++ A   SGH
Sbjct: 1041 ADSSRHSGIPRRQASS-AVRDSGH 1063



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 56/250 (22%), Positives = 92/250 (36%), Gaps = 38/250 (15%)

Query: 43   PAGGTGQRRGSGSSPSADQQG----------AQDREEEAAAAPAADQQRAQDREEEAAAA 92
            P    G R+GS    S D+ G           Q R + +           Q R EE +  
Sbjct: 1493 PGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGD 1552

Query: 93   PAPTSSGHRTE-------KRKPQQPQCRPAGG-TGQRRGSGSSPSADQQGAQDREEEAAA 144
             +  S     E        R  Q  Q   AG  T +R+GS  S   D +G  +  E  + 
Sbjct: 1553 GSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSE 1612

Query: 145  APAPTSRGHRTEK-----RKPQQPQRRPA-----AGTGQRRGSRSSPSADQQGAQDREEE 194
            + +    G   E+     R P+  Q   A     A + ++ G+R + ++    A   +E+
Sbjct: 1613 SASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQ 1672

Query: 195  AAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRR-----GSRSSPSADQQRAQDREEEAA 249
            A ++P     G R   R +Q       +GTG+R+     G   +  +   +A D E  + 
Sbjct: 1673 ARSSP-----GERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSE 1727

Query: 250  AAPAPTSSGH 259
             +   + S H
Sbjct: 1728 ESDTQSVSAH 1737



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 39/207 (18%), Positives = 78/207 (37%), Gaps = 8/207 (3%)

Query: 55   SSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRP 114
            S+ S+ Q G +  E  +    A+ Q++A+    E   +    S+   T+    ++     
Sbjct: 1646 SAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSV 1705

Query: 115  AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQR 174
             G +G R GS  S ++D +G  +  +  + +    +  H       QQ  +    G    
Sbjct: 1706 VGDSGNR-GSSGSQASDSEGHSEESDTQSVSAHGQAGPH-------QQSHQESTRGQSGE 1757

Query: 175  RGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSP 234
            R  RS     Q    ++ E A     P++ G +  + ++ +   R +A    +   R  P
Sbjct: 1758 RSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHP 1817

Query: 235  SADQQRAQDREEEAAAAPAPTSSGHRT 261
             + +   Q    E +   +  S  H +
Sbjct: 1818 GSSRGGRQGSHYEQSVDSSGHSGSHHS 1844



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 54/223 (24%), Positives = 78/223 (34%), Gaps = 32/223 (14%)

Query: 47   TGQRRGSGSSPSADQQ---GAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTE 103
            TG R+GS    + D      +QD ++     P + ++  Q    E +   +  S  H + 
Sbjct: 814  TGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSH 873

Query: 104  KRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQP 163
                        G +   RG   S SA +     R EE +   +  S     E       
Sbjct: 874  TTSQ--------GRSDASRGQSGSRSASRT---TRNEEQSRDGSRHSGSRHHEASSHADI 922

Query: 164  QRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAG 223
             R   AG GQ  GSR+S       +QD + E          GH  +  +      R   G
Sbjct: 923  SRHSQAGQGQSEGSRTSRRQGSSVSQDSDSE----------GHSEDSERWSGSASRNHRG 972

Query: 224  TGQ---RRGSRSSPSADQQRA-----QDREEEAAAAPAPTSSG 258
            + Q   R GSR   S  + RA      D   ++    A TSSG
Sbjct: 973  SAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSG 1015



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 54/275 (19%), Positives = 96/275 (34%), Gaps = 28/275 (10%)

Query: 3    PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
            PR   + TR  +  +S +G +   +  ++   P  +         GQ   +GS  S  +Q
Sbjct: 1537 PRSASRQTRNEE--QSGDGSR---HSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSR-RQ 1590

Query: 63   GAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEK-RKPQQPQCRPAGGTGQR 121
            G+   ++  +   + D +R  +         A   S H +   R  Q+ +          
Sbjct: 1591 GSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESS 1650

Query: 122  RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQR------- 174
            R SG+  +    G Q    +  A  +P   G R   R  Q       +GTG+R       
Sbjct: 1651 RQSGTRHAETSSGGQAASSQEQARSSP---GERHGSRHQQSADSSTDSGTGRRQDSSVVG 1707

Query: 175  ----RGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGS 230
                RGS  S ++D +G  +  +  + +    +  H       QQ       G    R  
Sbjct: 1708 DSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPH-------QQSHQESTRGQSGERSG 1760

Query: 231  RSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKRK 265
            RS     Q    ++ E A     P++ G +  + +
Sbjct: 1761 RSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHE 1795



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 51/245 (20%), Positives = 83/245 (33%), Gaps = 38/245 (15%)

Query: 36   QQQPQCQPAGGTGQRRGSGSSPSADQ-------------QGAQDREEEAAAAPAADQQRA 82
            Q   +  P    G R+GS    S D+             QG  D     + + +A +Q  
Sbjct: 1162 QDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTR 1221

Query: 83   QDREEEAAAAPAPTSSGHR-------TEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGA 135
            +D++    +      SG R        +  +  Q     + G+   R  GSS S D    
Sbjct: 1222 KDKQ----SGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSE 1277

Query: 136  QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEA 195
            +  ++    + + +   H + + + +   R P      R     S  + +Q      E  
Sbjct: 1278 RHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTE-- 1335

Query: 196  AAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPT 255
                   S  H       +Q +  P    G+R GSR   SAD  R        A++ A  
Sbjct: 1336 -------SSSHGQAVSSHEQARSSP----GERHGSRHQQSADSSRHSGIGHRQASS-AVR 1383

Query: 256  SSGHR 260
             SGHR
Sbjct: 1384 DSGHR 1388



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 55/273 (20%), Positives = 101/273 (36%), Gaps = 29/273 (10%)

Query: 7   EQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQ--RRGSGSSPSADQQGA 64
           +  +++ + R  +     L+  +T+  R  +  Q + + G  +   R SGS+       A
Sbjct: 266 KSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSA 325

Query: 65  QDREEEAAAAPAA-DQQRAQ-----DREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGT 118
            ++  + +  P + D+ RA      D   ++    A TSS  +T     Q          
Sbjct: 326 WEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQA-----RSSP 380

Query: 119 GQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSR 178
           G+R GSG   SAD            A+ A + RGHR         Q   + G  +   ++
Sbjct: 381 GERHGSGHQQSAD-SSRHSATGRGQASSAVSDRGHRGSSGS----QASDSEGHSENSDTQ 435

Query: 179 SSPSADQQGAQDREEEAAAAPVPTSRGHRT-----EKRKRQQPQC---RPAAGTGQRRGS 230
           S     + G + +  + +       R  R+     +    +QP     R    TG R+GS
Sbjct: 436 SVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGS 495

Query: 231 RSSPSADQQR---AQDREEEAAAAPAPTSSGHR 260
               + D  R   +Q+ ++     P  +  G +
Sbjct: 496 HHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQ 528



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 50/218 (22%), Positives = 81/218 (37%), Gaps = 18/218 (8%)

Query: 47   TGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHR----- 101
            +G R  SGS  +  +  ++D + ++ +A        Q  +E A      +S   R     
Sbjct: 1385 SGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQ 1444

Query: 102  -TEKRKPQQPQCRPAGGTGQRRGS---GSSPSADQQGAQDREEEAAAAPAPTSRGHRTEK 157
             +   + +    + A  TG R+GS    +  S+    +QD ++     P  +SRG R   
Sbjct: 1445 VSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPG-SSRGGRQGS 1503

Query: 158  RKPQQPQRRPAAG------TGQRRGSRSSPSADQQGA--QDREEEAAAAPVPTSRGHRTE 209
               Q   R   +G      T Q R   S   +  + A  Q R EE +      S     E
Sbjct: 1504 YHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHE 1563

Query: 210  KRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEE 247
               R         G G+  GS++S       +QDR+ E
Sbjct: 1564 PSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSE 1601



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 60/305 (19%), Positives = 99/305 (32%), Gaps = 50/305 (16%)

Query: 3    PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62
            PR  ++D         S       + +T         Q Q     G+R GS    SAD  
Sbjct: 1633 PRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSS 1692

Query: 63   ---GAQDREEEAAAAPAADQ----QRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPA 115
               G   R++ +    + ++     +A D E  +  +   + S H       Q  Q    
Sbjct: 1693 TDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTR 1752

Query: 116  GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR--------- 166
            G +G+R G   S    Q    ++ E A     P++ G +  + +  +   R         
Sbjct: 1753 GQSGERSGRSGS-FLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQD 1811

Query: 167  -----PAAGTGQRRGSRSSPSADQQG----------AQDREE--EAAAAPVPTSRGHRTE 209
                 P +  G R+GS    S D  G          +Q+R +     +     SR  R E
Sbjct: 1812 TIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNE 1871

Query: 210  KRK----------------RQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPA 253
            K+                 R         G GQ  G R+S +     +QD + +  +  +
Sbjct: 1872 KQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDS 1931

Query: 254  PTSSG 258
               SG
Sbjct: 1932 ERWSG 1936



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 48/226 (21%), Positives = 82/226 (36%), Gaps = 19/226 (8%)

Query: 51   RGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHR-------TE 103
            RG   S ++D +G  +  +  + +        Q   +E+A   +  SSG         + 
Sbjct: 2037 RGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVST 2096

Query: 104  KRKPQQPQCRPAGGTGQRRGSGSSPSADQQ---GAQDREEEAAAAPAPTSRGHRTEKRKP 160
              + +    + A  TG R+GS    + D      +Q+ ++     P P SRG R    + 
Sbjct: 2097 HEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGP-SRGGRQGSHQE 2155

Query: 161  QQPQRRPAAGTGQRRGS---RSSPSADQQGAQDR-----EEEAAAAPVPTSRGHRTEKRK 212
            Q   R   +G+     +   RS  S  Q G++       ++E +      S  H  E   
Sbjct: 2156 QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASS 2215

Query: 213  RQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSG 258
                      G GQ  G R+S       +QD + E  +  +   SG
Sbjct: 2216 WADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSG 2261



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 44/232 (18%), Positives = 82/232 (35%), Gaps = 19/232 (8%)

Query: 52   GSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHR-------TEK 104
            GS  S ++D +G  +  +  + +        Q   +E+A   +   SG         +  
Sbjct: 3334 GSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTH 3393

Query: 105  RKPQQPQCRPAGGTGQRRGSGSSPSADQQ---GAQDREEEAAAAPAPTSRGHRTEKRKPQ 161
             + +    R    TG+R+GS    + D      +Q+ ++     P  + RG R      Q
Sbjct: 3394 EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRG-RQGSHYEQ 3452

Query: 162  QPQRRPAAGT--------GQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKR 213
               R   +G+        G+   SR    +     Q R +E +      S  H  E   +
Sbjct: 3453 SVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQ 3512

Query: 214  QQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKRK 265
                    +G GQ  G R+S +     +QD + +  +  +   SG  +   +
Sbjct: 3513 ADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHR 3564



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 52/234 (22%), Positives = 82/234 (35%), Gaps = 21/234 (8%)

Query: 51  RGSGSSPSADQQGAQDREE--------EAAAAPAADQQRAQDREEEAAAAPAPTSSGHRT 102
           RGS  S + D +G  +  +        +A     + Q+ A+DR  E +           T
Sbjct: 740 RGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVST 799

Query: 103 EKRKPQQPQCRPAGGTGQRRGSGSSPSADQQ---GAQDREEEAAAAPAPTSRGHRTEKRK 159
            K+  +         TG R+GS    + D      +QD ++     P  + RG R     
Sbjct: 800 HKQS-ESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRG-RQGSHH 857

Query: 160 PQQPQRRPAAGTGQRRGS---RSSPSADQQGAQD-----REEEAAAAPVPTSRGHRTEKR 211
            Q   R   +G+     +   RS  S  Q G++      R EE +      S     E  
Sbjct: 858 EQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEAS 917

Query: 212 KRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKRK 265
                     AG GQ  GSR+S       +QD + E  +  +   SG  +   +
Sbjct: 918 SHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHR 971



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 52/218 (23%), Positives = 78/218 (35%), Gaps = 37/218 (16%)

Query: 43   PAGGTGQRRGSGSSPSADQQG----------AQDREEEAAAAPAADQQRAQDREEEAAAA 92
            P    G R+G     S D  G          +Q R + +     +       R EE +  
Sbjct: 3114 PGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGD 3173

Query: 93   PAPTS-------SGHRTEKRKPQQPQCRPAGGTGQRR-GSGSSPSADQQG-AQDREEEAA 143
             +  S       S H    R  Q  Q +  G    RR GS  S  +D +G ++D E  + 
Sbjct: 3174 SSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSG 3233

Query: 144  AAPAPTSRGHR-TEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPT 202
            +A    SR HR + + + +   R P +    R G   S    +Q      E ++     +
Sbjct: 3234 SA----SRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAAS 3289

Query: 203  SRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240
            S      ++ R  P        G+R GSR   SAD  R
Sbjct: 3290 SH-----EQARSSP--------GERHGSRHQQSADSSR 3314



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 51/232 (21%), Positives = 84/232 (36%), Gaps = 20/232 (8%)

Query: 47   TGQRRGSGSSPSADQQGAQDREEEAAAA--PAADQQRAQDREEEAAAAPAPTSSG----H 100
            +G R  SGS  S  +  ++D + ++ +A   A   Q++        +A     SG     
Sbjct: 3654 SGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQ 3713

Query: 101  RTEKRKPQQPQCRPAGGTGQRRGSGSSPSAD--QQGAQDREEEAAAAPAPTSRGHRTEKR 158
             +   + +    R    TG R+GS    + D  +  A    ++       + RG R    
Sbjct: 3714 VSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSY 3773

Query: 159  KPQQPQRRPAAG------TGQRRGSRS-SPSADQQGAQDREEEAAAAPVPTSRGHRTEKR 211
              Q   R   +G      T Q R   S   S  +  +++   E  +       G R  + 
Sbjct: 3774 HEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEA 3833

Query: 212  KRQQPQCRPA-AGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTE 262
              Q    R + +G G+  GSR S       +QD + EA     P  S  R+E
Sbjct: 3834 STQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEA----YPEDSERRSE 3881



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 49/235 (20%), Positives = 80/235 (34%), Gaps = 31/235 (13%)

Query: 43  PAGGTGQRRGSGSSPSADQQG----------AQDREEEAAAAPAADQQRAQDREEEAAAA 92
           P    G R+GS    S ++ G          +Q R + +     +     Q R EE +  
Sbjct: 520 PGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSG- 578

Query: 93  PAPTSSGHRTEKRKPQQPQCRPAG-GTGQRRG------SGSSPSADQQGAQDREEEAAAA 145
                SG R  +   Q    R +  G GQ  G       GSS S D       E+    +
Sbjct: 579 DGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWS 638

Query: 146 PAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRG 205
            + +   H + + + +   R P +    R G   S  + ++      + +++    +S  
Sbjct: 639 GSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSH- 697

Query: 206 HRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHR 260
                      Q R +AG  +R GSR    +             A+ A   SGHR
Sbjct: 698 ----------EQARSSAG--ERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHR 740



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 49/217 (22%), Positives = 74/217 (34%), Gaps = 25/217 (11%)

Query: 47  TGQRRGSGSSPSADQQ---GAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTE 103
           TG R+GS    + D      +Q+ ++     P + +   Q    E +       SGH   
Sbjct: 489 TGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSV----NRSGHSGS 544

Query: 104 KRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQP 163
                  Q R     GQ   SGS  ++     Q R EE +      S     E       
Sbjct: 545 HHSHTTSQGRSDASHGQ---SGSRSAS----RQTRNEEQSGDGTRHSGSRHHEASSQADS 597

Query: 164 QRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAG 223
            R    G GQ  G R+S +     +QD +          S+GH  +  +      R   G
Sbjct: 598 SRHSQVGQGQSSGPRTSRNQGSSVSQDSD----------SQGHSEDSERWSGSASRNHHG 647

Query: 224 TGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHR 260
           + Q + SR      +   +DR     +A +   SG R
Sbjct: 648 SAQEQ-SRDGSRHPRSHHEDRAGHGHSADSSRKSGTR 683



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 52/256 (20%), Positives = 86/256 (33%), Gaps = 23/256 (8%)

Query: 7    EQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ---G 63
            ++ TR R    S     +L    T         +  P+  TG R+GS    + D      
Sbjct: 3693 QESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPS--TGGRQGSRHEQARDSSRHSA 3750

Query: 64   AQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRG 123
            +Q+ ++     P + +   Q    E +   +  S  H +             G +    G
Sbjct: 3751 SQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQ--------GRSDASHG 3802

Query: 124  SGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSA 183
               S SA ++    R EE +   +  S     E        R   +G G+  GSR S   
Sbjct: 3803 QSGSRSASRE---TRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQ 3859

Query: 184  DQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQD 243
                +QD + EA     P     R+E   R       ++    R GSR   S+ +  A  
Sbjct: 3860 GSSVSQDSDSEA----YPEDSERRSESASRNH---HGSSREQSRDGSRHPGSSHRDTASH 3912

Query: 244  REEEAAAAPAPTSSGH 259
             +     + + T+  H
Sbjct: 3913 VQSSPVQSDSSTAKEH 3928



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 46/213 (21%), Positives = 73/213 (34%), Gaps = 36/213 (16%)

Query: 47   TGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRK 106
            +G R  SGS  S ++  ++D + ++ +A        Q  +E A      T SGH      
Sbjct: 2682 SGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGET-SGH------ 2734

Query: 107  PQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR 166
                               S     Q    ++ E +     P++RG +  + +  Q   R
Sbjct: 2735 -------------------SGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR 2775

Query: 167  PAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQ 226
             +A    +   R  P + + G Q    E +      S GH          Q R  A  GQ
Sbjct: 2776 HSASQDGQDTIRGHPGSSRGGRQGYHHEHSV----DSSGHSGSHHSHTTSQGRSDASRGQ 2831

Query: 227  RRGSRSSPSADQQRAQDREEEAAAAPAPTSSGH 259
              GSRS+      R    EE++      + S H
Sbjct: 2832 -SGSRSA-----SRTTRNEEQSGDGSRHSGSRH 2858



 Score = 37.0 bits (84), Expect = 0.018
 Identities = 46/213 (21%), Positives = 74/213 (34%), Gaps = 36/213 (16%)

Query: 47   TGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRK 106
            +G R  SGS  S ++  ++D + ++ +A        Q  +E A      T SGH      
Sbjct: 3006 SGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGET-SGH------ 3058

Query: 107  PQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR 166
                               S     Q    ++ E +     P++RG +  + +  Q   R
Sbjct: 3059 -------------------SGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR 3099

Query: 167  PAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQ 226
             +A    +   R  P + + G Q    E +      S GH          Q R  A  GQ
Sbjct: 3100 HSASQYGQDTIRGHPGSSRGGRQGYHHEHSV----DSSGHSGSHHSHTTSQGRSDASRGQ 3155

Query: 227  RRGSRSSPSADQQRAQDREEEAAAAPAPTSSGH 259
              GSRS+      R    EE++  +   + S H
Sbjct: 3156 -SGSRSA-----SRTTRNEEQSGDSSRHSVSRH 3182



 Score = 36.2 bits (82), Expect = 0.030
 Identities = 41/179 (22%), Positives = 64/179 (35%), Gaps = 23/179 (12%)

Query: 83  QDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQG-AQDREEE 141
           + R  +  ++     S H    + P Q        T +RRGS  S   D +G ++D E  
Sbjct: 259 RSRSSDGKSSSQVNRSRHENTSQVPLQES-----RTRKRRGSRVSQDRDSEGHSEDSERH 313

Query: 142 AAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVP 201
           + +A    SR H              +A    R GSR   S D+  A       ++    
Sbjct: 314 SGSA----SRNHHG------------SAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSG 357

Query: 202 TSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHR 260
           T     + + +      +  +  G+R GS    SAD  R         A+ A +  GHR
Sbjct: 358 TRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSR-HSATGRGQASSAVSDRGHR 415



 Score = 36.2 bits (82), Expect = 0.030
 Identities = 50/229 (21%), Positives = 81/229 (35%), Gaps = 18/229 (7%)

Query: 47   TGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTS--SG----H 100
            +G R  SGS  S  +  ++D + ++ +A        Q  +E      A  S  SG     
Sbjct: 2358 SGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQ 2417

Query: 101  RTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQG---AQDREEEAAAAPAPTSRGHRTEK 157
             +   + +    R    TG R+GS    + D      +Q+ ++     P  +S G R   
Sbjct: 2418 VSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGG-RQGS 2476

Query: 158  RKPQQPQRRPAAG------TGQRRGSRSSPSADQQGA--QDREEEAAAAPVPTSRGHRTE 209
               Q   R   +G      T Q R   S   +  + A  Q R +E +      S     E
Sbjct: 2477 HYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHE 2536

Query: 210  KRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSG 258
               R         G GQ  G R+S +     +QD + +  +  +   SG
Sbjct: 2537 ASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSG 2585



 Score = 32.7 bits (73), Expect = 0.34
 Identities = 57/238 (23%), Positives = 80/238 (33%), Gaps = 52/238 (21%)

Query: 48   GQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKP 107
            GQ  GS  S       +QD + E           ++D E  + +A    S  HR   ++ 
Sbjct: 3200 GQSEGSRRSRRQGSSVSQDSDSEG---------HSEDSERWSGSA----SRNHRGSVQEQ 3246

Query: 108  QQPQCR-PAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR 166
             +   R P      R G G S    +Q      E ++   A +S  H   +  P      
Sbjct: 3247 SRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASS--HEQARSSP------ 3298

Query: 167  PAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSR-------------GHRTEKRKR 213
                 G+R GSR   SAD           A++ V  SR             GH +E+   
Sbjct: 3299 -----GERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGH-SEESDT 3352

Query: 214  QQPQCRPAAGTGQ---------RRGSRSSPSAD--QQRAQDREEEAAAAPAPTSSGHR 260
            Q       AG  Q         R G RS  S     Q +   + E+A     TS+G R
Sbjct: 3353 QSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRR 3410


>gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo
           sapiens]
          Length = 384

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 66/229 (28%), Positives = 85/229 (37%), Gaps = 39/229 (17%)

Query: 27  NEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDRE 86
           + +T+P      P+ +   G   R GSG++ SA        +  +   PAA   R     
Sbjct: 76  DSRTRPAARPPHPRTRSPPG---RSGSGTTFSAVPPRPSQHQSGSRLRPAAPGPRPGCSS 132

Query: 87  EEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ-RRGSGSSPSADQQGAQDREEEAAAA 145
             A+ APA   +  RT       P    +GG+G   RG GS    DQ GA  R   A   
Sbjct: 133 ARASPAPAAPQAAART------APGRAASGGSGPGSRGQGS----DQVGA--RPSRAGGQ 180

Query: 146 PAP-TSRGHRTEKRKPQQPQR--------RPAAGTGQR------------RGSRSSPSAD 184
           P P T R  R   R+  +P R        RP +GTG R              + SSPSAD
Sbjct: 181 PPPLTCRRCRAAPRRSARPFRRPGLPLKSRPGSGTGARSCGTWGSGGGPGTAAASSPSAD 240

Query: 185 --QQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSR 231
                 Q       A  V    G R    +  QP CR  +    RR  R
Sbjct: 241 FSSDSPQPIIIFGGALRVRGCGGRRRSNGQGTQPGCRLLSPAPPRRRYR 289


>gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo
           sapiens]
          Length = 384

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 66/229 (28%), Positives = 85/229 (37%), Gaps = 39/229 (17%)

Query: 27  NEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDRE 86
           + +T+P      P+ +   G   R GSG++ SA        +  +   PAA   R     
Sbjct: 76  DSRTRPAARPPHPRTRSPPG---RSGSGTTFSAVPPRPSQHQSGSRLRPAAPGPRPGCSS 132

Query: 87  EEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ-RRGSGSSPSADQQGAQDREEEAAAA 145
             A+ APA   +  RT       P    +GG+G   RG GS    DQ GA  R   A   
Sbjct: 133 ARASPAPAAPQAAART------APGRAASGGSGPGSRGQGS----DQVGA--RPSRAGGQ 180

Query: 146 PAP-TSRGHRTEKRKPQQPQR--------RPAAGTGQR------------RGSRSSPSAD 184
           P P T R  R   R+  +P R        RP +GTG R              + SSPSAD
Sbjct: 181 PPPLTCRRCRAAPRRSARPFRRPGLPLKSRPGSGTGARSCGTWGSGGGPGTAAASSPSAD 240

Query: 185 --QQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSR 231
                 Q       A  V    G R    +  QP CR  +    RR  R
Sbjct: 241 FSSDSPQPIIIFGGALRVRGCGGRRRSNGQGTQPGCRLLSPAPPRRRYR 289


>gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 384

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 66/229 (28%), Positives = 85/229 (37%), Gaps = 39/229 (17%)

Query: 27  NEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDRE 86
           + +T+P      P+ +   G   R GSG++ SA        +  +   PAA   R     
Sbjct: 76  DSRTRPAARPPHPRTRSPPG---RSGSGTTFSAVPPRPSQHQSGSRLRPAAPGPRPGCSS 132

Query: 87  EEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ-RRGSGSSPSADQQGAQDREEEAAAA 145
             A+ APA   +  RT       P    +GG+G   RG GS    DQ GA  R   A   
Sbjct: 133 ARASPAPAAPQAAART------APGRAASGGSGPGSRGQGS----DQVGA--RPSRAGGQ 180

Query: 146 PAP-TSRGHRTEKRKPQQPQR--------RPAAGTGQR------------RGSRSSPSAD 184
           P P T R  R   R+  +P R        RP +GTG R              + SSPSAD
Sbjct: 181 PPPLTCRRCRAAPRRSARPFRRPGLPLKSRPGSGTGARSCGTWGSGGGPGTAAASSPSAD 240

Query: 185 --QQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSR 231
                 Q       A  V    G R    +  QP CR  +    RR  R
Sbjct: 241 FSSDSPQPIIIFGGALRVRGCGGRRRSNGQGTQPGCRLLSPAPPRRRYR 289


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 51/208 (24%), Positives = 69/208 (33%), Gaps = 32/208 (15%)

Query: 27  NEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDRE 86
           ++   P  P  +PQ  P  G  Q +G    P   Q       ++    P   + +     
Sbjct: 146 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQG---- 201

Query: 87  EEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAP 146
                 P P     R+ +  P +PQ  P  G  Q +G    P   Q             P
Sbjct: 202 ------PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ------------GP 243

Query: 147 APTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGH 206
            P           P +PQ  PA G G +  S  SP    QG   +E      P P + G+
Sbjct: 244 PPQGGNKPQGPPPPGKPQGPPAQG-GSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGN 302

Query: 207 RTEKRKRQQPQCRPAAGTGQRRGSRSSP 234
                  QQPQ  PA   GQ +G    P
Sbjct: 303 ------PQQPQAPPA---GQPQGPPRPP 321



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 52/236 (22%), Positives = 73/236 (30%), Gaps = 30/236 (12%)

Query: 27  NEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDRE 86
           ++   P  P  +PQ  P  G  Q +G    P   Q             P   + +     
Sbjct: 85  DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQG---- 140

Query: 87  EEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQ----QGAQDRE--- 139
                 P P     R+ +  P +PQ  P  G  Q +G    P   Q    QG +  +   
Sbjct: 141 ------PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPP 194

Query: 140 -EEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAA 198
                  P P     R+ +  P +PQ  P  G  Q +G    P    QG   +       
Sbjct: 195 PPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGP-PPPPGKPQGPPPQGGNKPQG 253

Query: 199 PVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAP 254
           P P  +           PQ  PA G  + + +RS P   Q   Q         P P
Sbjct: 254 PPPPGK-----------PQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPP 298



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 41/178 (23%), Positives = 57/178 (32%), Gaps = 16/178 (8%)

Query: 93  PAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQ----QGAQDRE----EEAAA 144
           P P     R+ +  P +PQ  P  G  Q +G    P   Q    QG    +         
Sbjct: 80  PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQ 139

Query: 145 APAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQ----QGAQDRE----EEAA 196
            P P     R+ +  P +PQ  P  G  Q +G    P   Q    QG +  +        
Sbjct: 140 GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKP 199

Query: 197 AAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAP 254
             P P     R+ +    +PQ  P  G  Q +G    P   Q        +    P P
Sbjct: 200 QGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 257


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
            [Homo sapiens]
          Length = 2903

 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 47/179 (26%), Positives = 70/179 (39%), Gaps = 17/179 (9%)

Query: 44   AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTE 103
            A GTG++R S  SP    Q  QD+    A + +     AQ +  + +A P P     +T+
Sbjct: 2358 AAGTGEQRQSKLSPQ--MQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQP-----QTQ 2410

Query: 104  KRKPQQP--QCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQ 161
             + P QP  Q +P   T     S     A    AQ  + + AA   P S        + Q
Sbjct: 2411 PQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQ 2470

Query: 162  QPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRP 220
             P         Q R   S+PS    G Q + +   + P+P       +   + QPQ +P
Sbjct: 2471 SPS--------QTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQP 2521



 Score = 34.7 bits (78), Expect = 0.088
 Identities = 35/118 (29%), Positives = 43/118 (36%), Gaps = 25/118 (21%)

Query: 62  QGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQR 121
           +G + R  +  AAPAA         E  A AP P           P  P   P GG   R
Sbjct: 2   RGRRGRPPKQPAAPAA---------ERCAPAPPPP----------PPPPTSGPIGGLRSR 42

Query: 122 -RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSR 178
            RGS     A  Q      E A      + RG  + +RKP  P   P + +   RG R
Sbjct: 43  HRGSSRGRWAAAQA-----EVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGGR 95


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.303    0.118    0.332 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,714,230
Number of Sequences: 37866
Number of extensions: 890390
Number of successful extensions: 11496
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 301
Number of HSP's successfully gapped in prelim test: 1332
Number of HSP's that attempted gapping in prelim test: 6510
Number of HSP's gapped (non-prelim): 4467
length of query: 265
length of database: 18,247,518
effective HSP length: 100
effective length of query: 165
effective length of database: 14,460,918
effective search space: 2386051470
effective search space used: 2386051470
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press