BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239508698 PREDICTED: similar to mucin [Homo sapiens] (265 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239508698 PREDICTED: similar to mucin [Homo sapiens] 534 e-152 gi|239754474 PREDICTED: similar to mucin [Homo sapiens] 498 e-141 gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo ... 409 e-114 gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 67 2e-11 gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 59 3e-09 gi|30795231 brain abundant, membrane attached signal protein 1 [... 57 2e-08 gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] 56 3e-08 gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 55 5e-08 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 55 6e-08 gi|153070260 myristoylated alanine-rich protein kinase C substra... 55 8e-08 gi|38788274 bromodomain PHD finger transcription factor isoform ... 55 8e-08 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 54 1e-07 gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 54 2e-07 gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ... 52 5e-07 gi|78042577 MAP7 domain containing 1 [Homo sapiens] 51 9e-07 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 51 1e-06 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 51 1e-06 gi|71274172 ankyrin repeat domain 56 [Homo sapiens] 51 1e-06 gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 50 2e-06 gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 50 2e-06 gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 50 2e-06 gi|239750916 PREDICTED: similar to hCG1803335 [Homo sapiens] 50 2e-06 gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 50 2e-06 gi|50962882 G patch domain containing 8 [Homo sapiens] 50 3e-06 gi|60097902 filaggrin [Homo sapiens] 49 3e-06 gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo ... 49 3e-06 gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo ... 49 3e-06 gi|239508962 PREDICTED: hypothetical protein [Homo sapiens] 49 3e-06 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 49 3e-06 gi|38788260 bromodomain PHD finger transcription factor isoform ... 49 5e-06 >gi|239508698 PREDICTED: similar to mucin [Homo sapiens] Length = 265 Score = 534 bits (1375), Expect = e-152 Identities = 265/265 (100%), Positives = 265/265 (100%) Query: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD Sbjct: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60 Query: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ 120 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ Sbjct: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ 120 Query: 121 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS 180 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS Sbjct: 121 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS 180 Query: 181 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR Sbjct: 181 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240 Query: 241 AQDREEEAAAAPAPTSSGHRTEKRK 265 AQDREEEAAAAPAPTSSGHRTEKRK Sbjct: 241 AQDREEEAAAAPAPTSSGHRTEKRK 265 >gi|239754474 PREDICTED: similar to mucin [Homo sapiens] Length = 417 Score = 498 bits (1281), Expect = e-141 Identities = 250/265 (94%), Positives = 251/265 (94%) Query: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD Sbjct: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60 Query: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ 120 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAP PTSSGHRTEKRK Q QC+PAGGTGQ Sbjct: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQ 120 Query: 121 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS 180 RRGS SSPSADQQ AQDREEEAAAAP PTSRGHRTEKRK QQPQRRPA GTGQRRGS SS Sbjct: 121 RRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSS 180 Query: 181 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240 PSADQQGAQDREEEAAAAP PTSRGHRTEKRK QQPQCRPA GTGQRRGSRSSPSADQQR Sbjct: 181 PSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPSADQQR 240 Query: 241 AQDREEEAAAAPAPTSSGHRTEKRK 265 AQDREEEAAAAPAPTS GHRTEKRK Sbjct: 241 AQDREEEAAAAPAPTSRGHRTEKRK 265 Score = 386 bits (992), Expect = e-108 Identities = 206/267 (77%), Positives = 210/267 (78%), Gaps = 35/267 (13%) Query: 34 RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAP------------------ 75 R + Q QCQPAGGTGQRRGS SSPSADQQ AQDREEEAAAAP Sbjct: 105 RKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQ 164 Query: 76 -----------------AADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGT 118 +ADQQ AQDREEEAAAAPAPTS GHRTEKRKPQQPQCRPAGGT Sbjct: 165 RRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGT 224 Query: 119 GQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSR 178 GQRRGS SSPSADQQ AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPA GTGQRRGS Sbjct: 225 GQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSG 284 Query: 179 SSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQ 238 SPSADQQGAQDREEEAAAAP PTS GHRTEKRKR Q QC+PA GTGQRRGS S SA+Q Sbjct: 285 YSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQ 344 Query: 239 QRAQDREEEAAAAPAPTSSGHRTEKRK 265 Q AQDREEEAAAAP PTSSGHRTEKRK Sbjct: 345 QGAQDREEEAAAAPVPTSSGHRTEKRK 371 Score = 354 bits (909), Expect = 4e-98 Identities = 192/249 (77%), Positives = 196/249 (78%), Gaps = 35/249 (14%) Query: 34 RPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA----------------- 76 R +QQPQ +PAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA Sbjct: 158 RKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 217 Query: 77 ------------------ADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGT 118 ADQQRAQDREEEAAAAPAPTS GHRTEKRKPQQPQ RPAGGT Sbjct: 218 CRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGT 277 Query: 119 GQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSR 178 GQRRGSG SPSADQQGAQDREEEAAAAPAPTS GHRTEKRK Q Q +PA GTGQRRGS Sbjct: 278 GQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSG 337 Query: 179 SSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQ 238 S SA+QQGAQDREEEAAAAPVPTS GHRTEKRK QQPQ RPAAGTGQRRGS SSPSADQ Sbjct: 338 CSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQ 397 Query: 239 QRAQDREEE 247 QRAQDREEE Sbjct: 398 QRAQDREEE 406 Score = 173 bits (439), Expect = 1e-43 Identities = 101/173 (58%), Positives = 109/173 (63%), Gaps = 39/173 (22%) Query: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG 63 +Q+ QD + + EK KP +PQ+ +PAGGTGQRRGSG SPSADQQG Sbjct: 238 QQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQR----RPAGGTGQRRGSGYSPSADQQG 293 Query: 64 AQDREEEAAAAPA-----------------------------------ADQQRAQDREEE 88 AQDREEEAAAAPA A+QQ AQDREEE Sbjct: 294 AQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEE 353 Query: 89 AAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEE 141 AAAAP PTSSGHRTEKRKPQQPQ RPA GTGQRRGSGSSPSADQQ AQDREEE Sbjct: 354 AAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQDREEE 406 >gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo sapiens] Length = 306 Score = 409 bits (1051), Expect = e-114 Identities = 222/293 (75%), Positives = 224/293 (76%), Gaps = 53/293 (18%) Query: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD Sbjct: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60 Query: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ 120 QQGA QDREEEAAAAPAPTS GHRTEKRKPQQPQ RPAGGTGQ Sbjct: 61 QQGA------------------QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQ 102 Query: 121 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS 180 RRGS SS SADQQGAQDREEEAAAAPAPTS GHRTEKRKPQQPQ RPAAGTGQRRGS S Sbjct: 103 RRGSRSSSSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCS 162 Query: 181 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQC------------------RPAA 222 PSADQQ AQDREEEA AAPVPTS GHRTEKRKR Q QC +PA Sbjct: 163 PSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAG 222 Query: 223 GTGQRRGSRSSPSADQQRAQDREEEA-----------------AAAPAPTSSG 258 GTGQRRGSRSSPSADQQRAQDREEEA AAAP PT+ G Sbjct: 223 GTGQRRGSRSSPSADQQRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGG 275 Score = 302 bits (774), Expect = 2e-82 Identities = 155/191 (81%), Positives = 159/191 (83%), Gaps = 4/191 (2%) Query: 79 QQRAQDREEEAAAAPAPTSSGHRTEKRKP----QQPQCRPAGGTGQRRGSGSSPSADQQG 134 +Q+ QD + EK KP QQPQC+PAGGTGQRRGSGSSPSADQQG Sbjct: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG 63 Query: 135 AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEE 194 AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPA GTGQRRGSRSS SADQQGAQDREEE Sbjct: 64 AQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEE 123 Query: 195 AAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAP 254 AAAAP PTS GHRTEKRK QQPQCRPAAGTGQRRGS SPSADQQRAQDREEEA AAP P Sbjct: 124 AAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVP 183 Query: 255 TSSGHRTEKRK 265 TSSGHRTEKRK Sbjct: 184 TSSGHRTEKRK 194 Score = 188 bits (477), Expect = 5e-48 Identities = 100/139 (71%), Positives = 109/139 (78%), Gaps = 1/139 (0%) Query: 128 PSADQQGAQDREEEAAAAPAPTSRGHRTEKRKP-QQPQRRPAAGTGQRRGSRSSPSADQQ 186 P +Q + R+ ++ +T+ +P QQPQ +PA GTGQRRGS SSPSADQQ Sbjct: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62 Query: 187 GAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREE 246 GAQDREEEAAAAP PTSRGHRTEKRK QQPQ RPA GTGQRRGSRSS SADQQ AQDREE Sbjct: 63 GAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREE 122 Query: 247 EAAAAPAPTSSGHRTEKRK 265 EAAAAPAPTSSGHRTEKRK Sbjct: 123 EAAAAPAPTSSGHRTEKRK 141 Score = 45.1 bits (105), Expect = 7e-05 Identities = 37/112 (33%), Positives = 45/112 (40%), Gaps = 40/112 (35%) Query: 13 RKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAA 72 R R S DQ ++ + QPQ +PAGGTGQRRG+ ++P G R Sbjct: 228 RGSRSSPSADQQRAQDREEEAA---QPQRRPAGGTGQRRGTAAAPVPTTGGTGQR----- 279 Query: 73 AAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGS 124 AAAPAPTS+ GTGQRRGS Sbjct: 280 --------------RGTAAAPAPTST------------------GTGQRRGS 299 >gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] Length = 819 Score = 67.0 bits (162), Expect = 2e-11 Identities = 66/265 (24%), Positives = 111/265 (41%), Gaps = 24/265 (9%) Query: 13 RKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDRE--EE 70 +KLR + ++ ++P + GG G + G +P + G + R ++ Sbjct: 272 KKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQK 331 Query: 71 AAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPS- 129 A A AA +R +++AA + R +KP++ + AG + RG G Sbjct: 332 ATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGA--KSRGGGDKKGL 389 Query: 130 --ADQQGA-------QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS 180 A ++G Q+ A APA RG ++K + + P+ + G R G Sbjct: 390 REAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKK 449 Query: 181 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240 P Q A+ + EA A SRG + + R++ AAGT R G S S Sbjct: 450 PRRRGQKARQKAAEAGAE----SRGDKKQGRQKAS-----AAGTKSRGGGLKSHSGKNLW 500 Query: 241 AQDREEEAAAAPAPTSSGHRTEKRK 265 + ++ EAA A T++G ++ RK Sbjct: 501 RRGQKAEAAGEKA-TAAGAKSRGRK 524 Score = 61.2 bits (147), Expect = 9e-10 Identities = 60/216 (27%), Positives = 87/216 (40%), Gaps = 23/216 (10%) Query: 46 GTGQRRGSGSSPSADQQGAQDREEEAAAAPAAD---QQRAQDREEEAAAAPAPTSSGHRT 102 G RR S+ A +G D++ A D + R Q+ A APA G + Sbjct: 365 GKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGS 424 Query: 103 EKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ 162 +K + + P+ + G R G G P Q A+ + EA A SRG + + R Sbjct: 425 KKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGA----ESRGDKKQGR---- 476 Query: 163 PQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAA 222 Q+ AAGT R G S S + ++ EAA T+ G ++ RK+ + Q A Sbjct: 477 -QKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKA-TAAGAKSRGRKQPRRQKPAVA 534 Query: 223 GTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSG 258 G R G S R+ + A A TS G Sbjct: 535 GAKSRVGGSKS----------RQRQKAVAAGATSHG 560 Score = 54.3 bits (129), Expect = 1e-07 Identities = 51/190 (26%), Positives = 84/190 (44%), Gaps = 28/190 (14%) Query: 63 GAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRR 122 G + R+ AA A + E++AAAA + G + R+ Q A TG ++ Sbjct: 82 GKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRGRKPRRRGQK----AAATGSKK 137 Query: 123 GSGSSPSADQQGAQDR---EEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTG------- 172 + + G+++R ++AAAA S+G ++PQ+ AAG Sbjct: 138 PRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGG-------EKPQKAAAAGAKSRSGKKP 190 Query: 173 QRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRS 232 +RRG++S D++G Q A + +RG R +K +R +P A G RRG Sbjct: 191 RRRGAKSRGDEDKKGRQ----REAKSRFGKTRGGRRKKHRRPKP---AAGGAKSRRGGGK 243 Query: 233 SPSADQQRAQ 242 P ++R Q Sbjct: 244 KPQKQRRRGQ 253 Score = 52.0 bits (123), Expect = 5e-07 Identities = 61/221 (27%), Positives = 102/221 (46%), Gaps = 36/221 (16%) Query: 16 RESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEA--AA 73 + ++ G + L KP R Q+ A TG ++ + + G+++R A AA Sbjct: 107 KAAAAGTKSLGGRGRKPRRRGQK-----AAATGSKKPRWRAQKSAAAGSKNRGAGAQKAA 161 Query: 74 APAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQ 133 A A + + ++ ++AAAA A + SG +KP +RRG+ S D++ Sbjct: 162 AAAGVKSQGGEKPQKAAAAGAKSRSG-----KKP------------RRRGAKSRGDEDKK 204 Query: 134 GAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQ-RRGSRSSPSADQQGAQDRE 192 G R+ EA + T G R + R+P +PAAG + RRG P ++ Q + Sbjct: 205 G---RQREAKSRFGKTRGGRRKKHRRP-----KPAAGGAKSRRGGGKKPQKQRRRGQ-KA 255 Query: 193 EEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSS 233 + V SRG +K+ R+Q Q AG +RRG+ ++ Sbjct: 256 ATGGKSRVGKSRG-GGDKKLRRQGQNAALAG-AKRRGAATA 294 Score = 47.4 bits (111), Expect = 1e-05 Identities = 73/308 (23%), Positives = 114/308 (37%), Gaps = 58/308 (18%) Query: 2 KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTG-------QRRGSG 54 KPR + Q + + G Q + ++PQ A G +RRG+ Sbjct: 137 KPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAGAKSRSGKKPRRRGAK 196 Query: 55 SSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEK---RKPQQPQ 111 S D++G Q RE ++ +R + R P P + G ++ + +KPQ+ + Sbjct: 197 SRGDEDKKGRQ-REAKSRFGKTRGGRRKKHRR------PKPAAGGAKSRRGGGKKPQKQR 249 Query: 112 CR----PAGG---TGQRRGSG------SSPSADQQGAQDR-EEEAAAAPAPTSRGHRTEK 157 R GG G+ RG G +A GA+ R A PA RG R K Sbjct: 250 RRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGPK 309 Query: 158 ----------RKPQQPQRR-----PAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPT 202 R ++P+RR AA G +RG A G + R+++ Sbjct: 310 SLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQ-------R 362 Query: 203 SRGHRTEKRKRQQPQCRPAAG---TGQRRGSRSSPSADQQRAQDREEEAAAAPA--PTSS 257 RG + ++K + G G R R + R Q+ A APA P Sbjct: 363 RRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGG 422 Query: 258 GHRTEKRK 265 G + +R+ Sbjct: 423 GSKKPRRR 430 Score = 45.4 bits (106), Expect = 5e-05 Identities = 72/329 (21%), Positives = 122/329 (37%), Gaps = 75/329 (22%) Query: 2 KPRQKEQDTRLRKLRESSE--GDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSA 59 KPR++ Q R + +E GD+ +K + + G G + SG + Sbjct: 449 KPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSR-------GGGLKSHSGKNLWR 501 Query: 60 DQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQ----------- 108 Q A+ E+A AA A + R Q R ++ A A A + G +++ + Sbjct: 502 RGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGG 561 Query: 109 --QPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR 166 Q R GG R+ ++ +A +G D++ A A ++ + K + R+ Sbjct: 562 GGNKQSRGGGGNKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGK--KAWRQ 619 Query: 167 PAAGTGQ-------RRGSRSSPSADQQ-----------GAQDR---------EEEAAAAP 199 AAGTG RRG + + +A++ G Q R E AAAA Sbjct: 620 KAAGTGAKSRKKPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAV 679 Query: 200 VPTSRGHRTEKRKR----------------------QQPQCRPAAGTG--QRRGSRSSPS 235 + + +R+R ++P+ + G G + RGS + S Sbjct: 680 GQEAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKS 739 Query: 236 ADQQRAQDREEEAAAAPAPTSSGHRTEKR 264 A+ R + AAA G +R Sbjct: 740 RGSGGAKSRSGKKAAASKSHGGGGAKRRR 768 Score = 44.3 bits (103), Expect = 1e-04 Identities = 65/268 (24%), Positives = 102/268 (38%), Gaps = 46/268 (17%) Query: 37 QQPQCQPAGGTGQRRGSGSSPSADQQGAQDRE--EEAAAAPAADQQRAQDREEEAAAAPA 94 +Q Q A G G G+ S G + R+ + AAAA Q ++AAA Sbjct: 546 RQRQKAVAAGATSHGGGGNKQSRGGGGNKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVT 605 Query: 95 PTSSGHRTEKRKPQQPQCRPAGGTGQ-------RRGSGSSPSADQQ-----------GAQ 136 + SG +K Q+ A GTG RRG + +A++ G Q Sbjct: 606 KSRSGDGGKKAWRQK-----AAGTGAKSRKKPWRRGQKDAAAAEKAWATGATSRGSGGKQ 660 Query: 137 DREEEAAAAPAPTSR----GHRTEKRKPQQPQRRPAAGTG-----------QRRGSRSSP 181 R ++ AAA + +S G E RK + +R + G G QRRG + Sbjct: 661 PRWQKPAAAGSESSAAAAVGQEAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRL 720 Query: 182 SADQQGAQDREEEAAAAPVPTSRGHRTEK-RKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240 + G + + A S G ++ +K + G +RRG + + ++ Sbjct: 721 GKSRGGGGAKSRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKA 780 Query: 241 AQDREEEAAAA-----PAPTSSGHRTEK 263 ++AAAA P S G R +K Sbjct: 781 VTAGGQKAAAAGGKKPPRVKSRGGRGQK 808 Score = 37.4 bits (85), Expect = 0.014 Identities = 41/172 (23%), Positives = 74/172 (43%), Gaps = 22/172 (12%) Query: 111 QCRPAGGTGQRRGSGSSPSAD--QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPA 168 QC A G R G G+ A + + E AA A + + G + ++ +R+ A Sbjct: 8 QCNQAAG---RAGPGAPLGAALARTPVELAAESAAPALSAAAAGVKILGSGDKKLRRQKA 64 Query: 169 AGTGQR---RGSRSS-----------PSADQQGAQDR---EEEAAAAPVPTSRGHRTEKR 211 A G++ RG + + +A GA++R E++AAAA + G + R Sbjct: 65 AAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRGRKPR 124 Query: 212 KRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEK 263 +R Q + + R +S+ + + R ++ AAAA + G + +K Sbjct: 125 RRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQK 176 Score = 31.6 bits (70), Expect = 0.75 Identities = 43/176 (24%), Positives = 64/176 (36%), Gaps = 50/176 (28%) Query: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQP------AGGTGQRRGSGSSP 57 ++ E + R+ R S GD + P Q+ +P GG + RGSG + Sbjct: 681 QEAEARKKPRRRRAKSRGDGG--QNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAK 738 Query: 58 SADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGG 117 S GA+ R + AAA S H GG Sbjct: 739 SRGSGGAKSRSGKKAAA----------------------SKSHG-------------GGG 763 Query: 118 TGQRRGSGSSPSADQQGAQDREEEAAAA-----PAPTSRGHRTEKRKP--QQPQRR 166 +RRG G+ + ++ ++AAAA P SRG R +K ++P RR Sbjct: 764 AKRRRGGGAKSRSGEKAVTAGGQKAAAAGGKKPPRVKSRGGRGQKAAAGGKKPLRR 819 >gi|158854042 hypothetical protein LOC222183 [Homo sapiens] Length = 653 Score = 59.3 bits (142), Expect = 3e-09 Identities = 70/286 (24%), Positives = 108/286 (37%), Gaps = 45/286 (15%) Query: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSS--PSADQ 61 R + RK R S + EK K +++P + G R SGSS PS Sbjct: 211 RDRSDSGSRRKRRHRSRSSKCKRKEKNKE---KKRPHTESPGRRSHRHSSGSSHSPSLSS 267 Query: 62 QGAQDREEEAAAAPAADQQRAQDREEEAAA-APAPTS-SGHRTEKRKPQQPQCRPAGGTG 119 + R + D+ R + + + +P+P+ SG + +R Q +G G Sbjct: 268 HYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQ--RSGAHG 325 Query: 120 QRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRS 179 R GS SP R + AAA APT E P+ +A + Q RG R+ Sbjct: 326 GRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPR------SAPSSQGRGGRA 379 Query: 180 SPSADQQGAQDREEEAA--AAPVPTSRGHRTEKRKRQQP--------------------Q 217 + A ++ + R + +A P RG R+R +P Sbjct: 380 AGGAGRRRRRRRRRRRSRSSASAPRRRG-----RRRPRPAPPRGSSRSLSRARSSSDSGS 434 Query: 218 CRPAAGTGQRRGSRSSPSADQQRAQD---REEEAAAAPAPTSSGHR 260 R A G G GS +RA++ R A+ +P+P + G R Sbjct: 435 GRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRR 480 Score = 59.3 bits (142), Expect = 3e-09 Identities = 61/238 (25%), Positives = 89/238 (37%), Gaps = 37/238 (15%) Query: 26 ENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDR 85 E KT R P+GG+G + S + GA +A +P R Sbjct: 285 EGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPR 344 Query: 86 EEEAAAAPAPTSSGHRTEKRKPQQPQC------RPAGGTGQRRGSGSSPSADQQGAQDRE 139 + AAA APT E P+ R AGG G+RR + + R Sbjct: 345 VRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRR----------RRRRRRR 394 Query: 140 EEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAP 199 ++A AP RG R + P + R + R SS S +GA P Sbjct: 395 RSRSSASAPRRRGRRRPRPAPPRGSSRSLS-----RARSSSDSGSGRGA------PGPGP 443 Query: 200 VPTS-RGH--RTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAP 254 P S RGH ++ K + P+ RPA+ + SP A +R + ++ +P P Sbjct: 444 EPGSERGHGGHGKRAKERPPRARPAS-------TSPSPGAHGRRGGPEGKSSSRSPGP 494 >gi|30795231 brain abundant, membrane attached signal protein 1 [Homo sapiens] Length = 227 Score = 56.6 bits (135), Expect = 2e-08 Identities = 48/209 (22%), Positives = 85/209 (40%), Gaps = 34/209 (16%) Query: 58 SADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGG 117 + + + A++++++A A ++ ++ E +AAA PA G K KP Q Sbjct: 13 NVNDEKAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEG----KEKPDQ-------- 60 Query: 118 TGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGS 177 G ++ A +EE A P T + P+ P++ AA Sbjct: 61 --DAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAA-------- 110 Query: 178 RSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCR----PAAGTGQRRGSRSS 233 P G + EAAAAP ++ E+ +++ + + PAA Q S + Sbjct: 111 ---PGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGA 167 Query: 234 PSAD-----QQRAQDREEEAAAAPAPTSS 257 P++D + A +E AA AP+S+ Sbjct: 168 PASDSKPGSSEAAPSSKETPAATEAPSST 196 Score = 47.0 bits (110), Expect = 2e-05 Identities = 50/197 (25%), Positives = 81/197 (41%), Gaps = 29/197 (14%) Query: 17 ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG-AQDREEEAAAAP 75 ++ E D+ E T+ ++ + Q A + + P D +G A+++E E AA Sbjct: 18 KAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAA 77 Query: 76 AADQQRAQDREEEAAAAPAPTSSGHRTEK----RKPQQPQCRPAGGTGQRRGSGSSPSAD 131 A +EEA A + G K + P+Q Q P G G +P A Sbjct: 78 A---------KEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAG-----GEAPKAA 123 Query: 132 QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSAD-----QQ 186 + A E A AA S+ E+ +P++ + PAA Q S +P++D + Sbjct: 124 EAAAAPAESAAPAAGEEPSK----EEGEPKKTE-APAAPAAQETKSDGAPASDSKPGSSE 178 Query: 187 GAQDREEEAAAAPVPTS 203 A +E AA P+S Sbjct: 179 AAPSSKETPAATEAPSS 195 >gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] Length = 2303 Score = 56.2 bits (134), Expect = 3e-08 Identities = 61/250 (24%), Positives = 90/250 (36%), Gaps = 32/250 (12%) Query: 36 QQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAP 95 Q P+ QP G G++R +G P++ +Q R + A +A+Q R + P Sbjct: 1412 QGPPRDQPGGPAGRQRPTGR-PTSARQAMGHRHKAGGAGRSAEQSRGAGKNRAGLELPL- 1469 Query: 96 TSSGHRTEKRKPQQPQCRPAGGTGQRRGSG-------SSPSADQ----QGAQDREEEAAA 144 R P P + G+ RG G ++P+ + G EE AA Sbjct: 1470 --------GRPPSAPADKDGSKPGRTRGDGALQSLCLTTPTEEAVYCFYGNDSDEEPPAA 1521 Query: 145 APAPTSRGHRTEKR--KPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPT 202 AP PT R R ++PQ R A + + P A Q + +E + + Sbjct: 1522 APTPTHRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAPPPARTQPSLIADETPPCYSLSS 1581 Query: 203 SRGHRTEKRKRQQPQCRPAA---------GTGQRRGSRSSPSADQQRAQDREEEAAAAPA 253 S +E + P P G G R S SP A ++ Q A Sbjct: 1582 SASSLSEPEPSEPPAVHPRGREPAVTKDPGPGGGRDSSPSPRAAEELLQRCISSALPRRR 1641 Query: 254 PTSSGHRTEK 263 P SG R K Sbjct: 1642 PPVSGLRRRK 1651 Score = 45.4 bits (106), Expect = 5e-05 Identities = 64/281 (22%), Positives = 101/281 (35%), Gaps = 62/281 (22%) Query: 44 AGGTG------QRRGSGSSPSADQ-QGAQDREEE------AAAAPAADQQRAQDREEEAA 90 AGG G +RR G +P+ + +GA D+E E AA PA ++ A Sbjct: 1308 AGGAGLHFAGHRRREEGPAPTGSRPRGAADQELELLRECLGAAVPARLRKVASALVPGRR 1367 Query: 91 AAPAP----------------------------TSSGHRTEKRKPQQPQCRPAGGTGQRR 122 A P P +S+ +++ P+ +P G G++R Sbjct: 1368 ALPVPVYMLVPAPAPAQEDDSCTDSAEGTPVNFSSAASLSDETLQGPPRDQPGGPAGRQR 1427 Query: 123 GSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSR---- 178 +G SA Q + A A SRG + + P RP + + GS+ Sbjct: 1428 PTGRPTSARQAMGHRHKAGGAGRSAEQSRGAGKNRAGLELPLGRPPSAPADKDGSKPGRT 1487 Query: 179 -----------SSPSADQ----QGAQDREEEAAAAPVPTSRGHRTEKR--KRQQPQCRPA 221 ++P+ + G EE AAAP PT R R R++PQ R Sbjct: 1488 RGDGALQSLCLTTPTEEAVYCFYGNDSDEEPPAAAPTPTHRRTSAIPRAFTRERPQGRKE 1547 Query: 222 AGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTE 262 A + + P A Q + +E +S+ +E Sbjct: 1548 APAPSKAAPAAPPPARTQPSLIADETPPCYSLSSSASSLSE 1588 >gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sapiens] Length = 699 Score = 55.5 bits (132), Expect = 5e-08 Identities = 59/251 (23%), Positives = 101/251 (40%), Gaps = 33/251 (13%) Query: 24 WLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA----ADQ 79 WL++ K P+++ Q A G ++ + S+D + + + EEE PA Sbjct: 57 WLKSAKV----PERKLQ---ANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPA 109 Query: 80 QRAQDREEEAAAAPAPTSSGHRT--------EKRKPQQ----PQCRPAGGTGQRRGSGSS 127 +R +AAA + +SS + +K++P Q PQ + A ++ S S Sbjct: 110 KRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDS 169 Query: 128 PSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR-PAAGTGQRRGSRSSPSADQQ 186 D + + E P T + + + P +P R P G+ S SS S+ Sbjct: 170 ---DSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSS 226 Query: 187 GAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREE 246 EE+AAA P +T +K+ + A T R S SS + +++++ Sbjct: 227 SDDSEEEKAAATP------KKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKK 280 Query: 247 EAAAAPAPTSS 257 P P SS Sbjct: 281 PMKNKPGPYSS 291 Score = 51.6 bits (122), Expect = 7e-07 Identities = 52/259 (20%), Positives = 100/259 (38%), Gaps = 29/259 (11%) Query: 6 KEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQ--PAGGTGQRRGSGSSPSADQQG 63 K T RK S + E E+ KP++ + P P ++ G+ P ++ Sbjct: 255 KAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPP--KKA 312 Query: 64 AQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRG 123 + ++ ++ ++D+ + EE+ A S T K P ++ Sbjct: 313 VEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKA--TTKPPP-----------AKKAA 359 Query: 124 SGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKR--------KPQQPQRRPAAGTGQRR 175 SS S+D ++D +EA + PA T++ + KP ++P G + Sbjct: 360 ESSSDSSDSDSSED--DEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLL 417 Query: 176 GSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPS 235 ++ S+ ++ + EEE V T++ T K P A G R S S S Sbjct: 418 TRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLP--AKQAPQGSRDSSSDSDS 475 Query: 236 ADQQRAQDREEEAAAAPAP 254 + + +++ ++A P Sbjct: 476 SSSEEEEEKTSKSAVKKKP 494 Score = 44.7 bits (104), Expect = 9e-05 Identities = 55/262 (20%), Positives = 93/262 (35%), Gaps = 56/262 (21%) Query: 17 ESSEGDQ-------WLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREE 69 +SSE D+ +N KP + P +PA Q G G + + EE Sbjct: 369 DSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEE 428 Query: 70 EAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPS 129 E++++ EEE T+ T K P + G+ SS Sbjct: 429 ESSSS-----------EEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRD-----SSSD 472 Query: 130 ADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ------PQRRPAAGTGQRRGSRSSPSA 183 +D +++ EE+ + + K+KPQ+ P + +A G+ S SS S Sbjct: 473 SDSSSSEEEEEKTSKSAV---------KKKPQKVAGGAAPSKPASAKKGKAESSNSSSSD 523 Query: 184 DQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQD 243 D ++ + + +P +PQ A GT + + +++ Sbjct: 524 DSSEEEEEKLKGKGSP---------------RPQAPKANGTSALTAQNGKAA---KNSEE 565 Query: 244 REEEAAAAPAPTSSGHRTEKRK 265 EEE A S +KRK Sbjct: 566 EEEEKKKAAVVVSKSGSLKKRK 587 Score = 43.5 bits (101), Expect = 2e-04 Identities = 55/249 (22%), Positives = 90/249 (36%), Gaps = 41/249 (16%) Query: 17 ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA 76 E S D E++K +P++ +PQ + A ++ S S D + + P Sbjct: 130 EESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDS---------DSDSSSEDEPP 180 Query: 77 ADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQP-QCRPAGGTGQRRGSGSSPSADQQGA 135 +Q+ P T + + + P +P + P G+ S SS S+ Sbjct: 181 KNQK------------PKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSD 228 Query: 136 QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEA 195 EE+AAA P T + + P + AA T R+ S S S+ EEE Sbjct: 229 DSEEEKAAATPKKTVPKKQVVAKAPVK-----AATTPTRKSSSSEDSSSD------EEEE 277 Query: 196 AAAPVPTSRGHRTEKRKRQQPQCRPAAGT--------GQRRGSRSSPSADQQRAQDREEE 247 P+ G + P + + GT Q+ S S+D+ + EE+ Sbjct: 278 QKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEK 337 Query: 248 AAAAPAPTS 256 A S Sbjct: 338 KPPTKAVVS 346 Score = 36.6 bits (83), Expect = 0.023 Identities = 38/176 (21%), Positives = 65/176 (36%), Gaps = 26/176 (14%) Query: 10 TRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGT---------GQRRGSGSSPSAD 60 TR S E E EKTK + +P+ G R S S S+ Sbjct: 418 TRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSS 477 Query: 61 QQGAQDREEEAA-----------AAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQ- 108 + +++ ++A AAP+ + + E + ++ + SS EK K + Sbjct: 478 SEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKG 537 Query: 109 --QPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ 162 +PQ A GT + + +++ EEE A S+ +KRK + Sbjct: 538 SPRPQAPKANGTSALTAQNGKAA---KNSEEEEEEKKKAAVVVSKSGSLKKRKQNE 590 Score = 32.0 bits (71), Expect = 0.57 Identities = 27/107 (25%), Positives = 44/107 (41%), Gaps = 4/107 (3%) Query: 18 SSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAA 77 SS D E E+ + +PQ A GT + +A ++ E++ AA + Sbjct: 520 SSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQ-NGKAAKNSEEEEEEKKKAAVVVS 578 Query: 78 DQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGS 124 + R++ AA A T + +K K Q P P G++R S Sbjct: 579 KSGSLKKRKQNEAAKEAETP---QAKKIKLQTPNTFPKRKKGEKRAS 622 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 55.1 bits (131), Expect = 6e-08 Identities = 70/287 (24%), Positives = 108/287 (37%), Gaps = 39/287 (13%) Query: 16 RESSEGDQWLENE-KTK-PLRPQQQ----PQCQPAGGTGQRRG-SGSSPSAD-------- 60 +E SE D +++ KT+ PLR + + P+ RR SGSSP Sbjct: 1554 QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPR 1613 Query: 61 -QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTG 119 Q G+ E A AP A +R++ P+P S TE P+ R A Sbjct: 1614 AQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSS-TESSPEHPPKSRTARRGS 1672 Query: 120 Q--------------RRGSGSSPSADQQGAQDREEEAAAA-PAPTSRGHRTEKRKPQQPQ 164 + RR S SSP ++ R +A++ P SR +R P Sbjct: 1673 RSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSS 1732 Query: 165 RRPA--AGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAA 222 PA + + +RR S SSP + R + SR R+ + K + + R + Sbjct: 1733 PEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRS-RSRREKTRTTRRRDRS 1791 Query: 223 GTGQRRGSRSSPSADQQRAQDREEEAAA----APAPTSSGHRTEKRK 265 G+ Q R S + R R + +PA S + +R+ Sbjct: 1792 GSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRR 1838 Score = 52.0 bits (123), Expect = 5e-07 Identities = 51/230 (22%), Positives = 93/230 (40%), Gaps = 27/230 (11%) Query: 47 TGQRRG-SGSSPSADQQGAQDREEEAAAAPAAD-QQRAQDREEEAAAAPAPTSSGHRTEK 104 T QRR S SSP + R + ++P + + R R + ++P P K Sbjct: 736 TSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCP--------K 787 Query: 105 RKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRK--PQQ 162 +K Q P R G+ Q + +P R ++++P P + ++ Sbjct: 788 QKSQTPPRRSRSGSSQPKAKSRTPP--------RRSRSSSSPPPKQKSKTPSRQSHSSSS 839 Query: 163 PQRRPAAGTGQRRGSRSSPSADQQGAQDREE---EAAAAPVPTSRGHRTEKRKRQQPQCR 219 P + +GT R+GS +SP A++Q + E++ P SR P Sbjct: 840 PHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRV 899 Query: 220 PAAGTGQRRGSRSSPSADQQRA----QDREEEAAAAPAPTSSGHRTEKRK 265 ++ ++ SRSS + +A + R +++P+P+ RT R+ Sbjct: 900 KSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR 949 Score = 52.0 bits (123), Expect = 5e-07 Identities = 57/233 (24%), Positives = 88/233 (37%), Gaps = 21/233 (9%) Query: 32 PLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAA 91 P P+ +C T QR SGS S DQ+ A P + R+ +E Sbjct: 1500 PSSPELNNKCL----TPQRERSGSESSVDQK-------TVARTPLGQRSRSGSSQELDVK 1548 Query: 92 APAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQG-AQDREEEAAAAPAPTS 150 A S R+E + + QR SGSSP D + R + ++P Sbjct: 1549 PSA--SPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD 1606 Query: 151 R---GHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQ---DREEEAAAAPVPTSR 204 + R + P+ + A R SRS S+ +G E++ P SR Sbjct: 1607 KPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSR 1666 Query: 205 GHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSS 257 R R +P+ + + +RR SRSSP ++ R +A++ T S Sbjct: 1667 TARRGSRSSPEPKTK-SRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRS 1718 Score = 51.6 bits (122), Expect = 7e-07 Identities = 60/227 (26%), Positives = 90/227 (39%), Gaps = 29/227 (12%) Query: 49 QRRGSGSSPSA-DQQGAQDREEEAAAAPAA-DQQRAQDR-EEEAAAAPAPTSSGH--RTE 103 +R SGSSP D G R + ++P D R R E ++P P + R Sbjct: 1437 RRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPR 1496 Query: 104 KRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQP 163 R P P+ T QR SGS S DQ+ A T G R+ Q+ Sbjct: 1497 SRSPSSPELNNKCLTPQRERSGSESSVDQK-----------TVARTPLGQRSRSGSSQEL 1545 Query: 164 QRRPAAGTGQRRGSRSSP--SADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQ----QPQ 217 +P+A +R S SSP A + + + ++P S+ + +R R + + Sbjct: 1546 DVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVK 1605 Query: 218 CRPAAGTGQRRGSRSS--PSADQQRAQDREEEAAAA-----PAPTSS 257 +P A + GS SS P A RA R + ++ P+P S Sbjct: 1606 DKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGS 1652 Score = 49.7 bits (117), Expect = 3e-06 Identities = 44/240 (18%), Positives = 82/240 (34%), Gaps = 21/240 (8%) Query: 31 KPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAA 90 +P + ++ + + S SS S+ G+ + E ++ P + + Sbjct: 2525 QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALK-----RV 2579 Query: 91 AAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTS 150 +P P E R P+ P +RR S SS S+ + ++++ + +S Sbjct: 2580 PSPTPAPKEAVREGRPPE-----PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2634 Query: 151 RGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRT-- 208 + PA Q +SP G +R + P+ + R R+ Sbjct: 2635 SSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG--ERRSRSPRKPIDSLRDSRSLS 2692 Query: 209 -----EKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEK 263 +R QP R + RGSR D + + +P P HR+ + Sbjct: 2693 YSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMR--HRSSR 2750 Score = 46.6 bits (109), Expect = 2e-05 Identities = 36/185 (19%), Positives = 77/185 (41%), Gaps = 14/185 (7%) Query: 85 REEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDRE----- 139 +EE PA T + E + + + R A G GSS ++ + ++ Sbjct: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEP 167 Query: 140 -------EEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDRE 192 E++++ +PT + + +K+K + RR + + +R +SS + + + Sbjct: 168 PKPYSLVRESSSSRSPTPK--QKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESK 225 Query: 193 EEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAP 252 + +P P S+ +K++++ PA + + S S+ SA +AAA Sbjct: 226 KRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAK 285 Query: 253 APTSS 257 T++ Sbjct: 286 THTTA 290 Score = 46.6 bits (109), Expect = 2e-05 Identities = 53/227 (23%), Positives = 88/227 (38%), Gaps = 23/227 (10%) Query: 55 SSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRP 114 SSP D+ +D++E++A P+ +R+ PAPT PQ P Sbjct: 332 SSPYEDKD--KDKKEKSATRPSPSPERSST----GPEPPAPTPLLAERHGGSPQPLATTP 385 Query: 115 AGGTGQRRGSGSSPSADQQGAQDRE--------EEAAAAPAPTSRGHRTEKRKPQQPQRR 166 S +SP+ D+ + E E + +P PT + R P+ P+ Sbjct: 386 LSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPT-KVSRHASSSPESPKPA 444 Query: 167 PAAGTGQRRGSRSSPSADQQGAQDREEEAAAAP---VPTSRGHRTEKRKRQQPQCRPAAG 223 PA G+ + S + G R++ + P + SR T KR R + + G Sbjct: 445 PAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRG 504 Query: 224 -----TGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKRK 265 + Q R SRS+ + R+ R + + P S R +R+ Sbjct: 505 HSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRR 551 Score = 45.8 bits (107), Expect = 4e-05 Identities = 56/247 (22%), Positives = 99/247 (40%), Gaps = 30/247 (12%) Query: 26 ENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDR 85 E + L ++ + + A G GSS D Q R A PA + + Sbjct: 120 ETHQLAELNEKKNERLRAAFGISDSYVDGSS--FDPQ----RRAREAKQPAPEPPKPYSL 173 Query: 86 EEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAA 145 E++++ +PT + +K+K + + + +R+ S S ++ + E + Sbjct: 174 VRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKS----SKKKKHRSESESKKRKH 229 Query: 146 PAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQD----REEEAAAAPVP 201 +PT + R K K ++ R RR RS+ SAD + D R AAA Sbjct: 230 RSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRST-SADSASSSDTSRSRSRSAAAKTHT 288 Query: 202 TSRGHRT------EKRKRQQPQCRPAAGTGQRRGS-------RSSPSADQQRAQDREEEA 248 T+ R+ + + P P + QR S SSP D+ + D++E++ Sbjct: 289 TALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDK--DKKEKS 346 Query: 249 AAAPAPT 255 A P+P+ Sbjct: 347 ATRPSPS 353 Score = 43.9 bits (102), Expect = 1e-04 Identities = 48/230 (20%), Positives = 81/230 (35%), Gaps = 13/230 (5%) Query: 49 QRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQ 108 QRRG SP + + +A + R+ R + R R Sbjct: 529 QRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRT 588 Query: 109 QPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPA 168 + R T RR S S A + ++ R + + R+ R P + R Sbjct: 589 PARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSR 648 Query: 169 AGTGQRRGSRSSPSADQQG-----AQDREEEAAAAPVPTSRGH---RTEKRKRQQPQC-- 218 + T RRG S + ++G R + + P RG RT +R R + + Sbjct: 649 SRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLV 708 Query: 219 ---RPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKRK 265 R + T QRRG S S + +++ + + + +P R R+ Sbjct: 709 RRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRR 758 Score = 42.7 bits (99), Expect = 3e-04 Identities = 51/268 (19%), Positives = 91/268 (33%), Gaps = 25/268 (9%) Query: 10 TRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREE 69 T R+ R S + P R + + + G + R S + + R Sbjct: 577 TPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSR 636 Query: 70 EAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPS 129 + A + + R++ + + R+ R P + R T RR G S S Sbjct: 637 SRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARR--GRSRS 694 Query: 130 ADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRG-SRSSPSADQQGA 188 + + R SR + R +R+ + T QRR S SSP + Sbjct: 695 RTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRI 754 Query: 189 QDREEEAAAAPVPTSRGHRT-----------EKRKRQQPQCRPAAGTGQ----------- 226 R + ++P ++ + K+K Q P R +G+ Q Sbjct: 755 SSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRR 814 Query: 227 RRGSRSSPSADQQRAQDREEEAAAAPAP 254 R S S P + + R+ ++++P P Sbjct: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHP 842 Score = 41.6 bits (96), Expect = 7e-04 Identities = 63/285 (22%), Positives = 104/285 (36%), Gaps = 44/285 (15%) Query: 1 MKPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQ---------QQPQC-QPAGGTGQR 50 + P + TR R +S E + ++ P PQ P+ +PA G Sbjct: 391 VNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSH 450 Query: 51 RGSGSSPSADQQ--GAQDREEEAAAAPAADQQRAQD---REEEAAAAPAPTSSGH----- 100 R SSP++ + G R++ + P+ R++ + + + PT GH Sbjct: 451 REISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRS 510 Query: 101 --------------------RTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREE 140 R R PQ+P + T QRRG S + ++ Sbjct: 511 PQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNT-QRRGRSRSARRGRSHSRSPAT 569 Query: 141 EAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPV 200 + +R R+ R P +RR + T RR SRS A + ++ R + Sbjct: 570 RGRSRSRTPARRGRSRSRTP--ARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRT 627 Query: 201 PTSRGHRTEKRKRQQPQCRPAAGTGQRRG-SRSSPSADQQRAQDR 244 + R+ R + R + T RRG SRS A + R++ R Sbjct: 628 RSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSR 672 Score = 38.5 bits (88), Expect = 0.006 Identities = 35/175 (20%), Positives = 66/175 (37%), Gaps = 13/175 (7%) Query: 63 GAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRR 122 GAQ AA PA +++ + ++++ + +SS + + G+ Sbjct: 2514 GAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS-----------SSGSSSSD 2562 Query: 123 GSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPS 182 GSS + A R AP R R + P + +RR ++ + S SS S Sbjct: 2563 SEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSS 2622 Query: 183 ADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQC--RPAAGTGQRRGSRSSPS 235 + + ++++ +S + + PQ +PA+ G R S S Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRS 2677 Score = 37.0 bits (84), Expect = 0.018 Identities = 50/241 (20%), Positives = 90/241 (37%), Gaps = 23/241 (9%) Query: 2 KPRQKEQDTRLRKLRESSEGDQWLENEKTKPL-RPQQQPQCQPAGGTGQRRGSGSSPSAD 60 + R + TR R + + +T P+ R + + + P T +R S +SP Sbjct: 1934 RSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPI--TRRRSRSRTSPVTR 1991 Query: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ 120 ++ R + + R + + P + R+ R P P+ Sbjct: 1992 RRS---RSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPR--------- 2039 Query: 121 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS 180 +R SP A ++ ++ R T+RG R+ R P +RR A+G+ R ++ Sbjct: 2040 KRSRSRSPLAIRRRSRSRTPR-------TARGKRSLTRSPPAIRRRSASGSSSDRSRSAT 2092 Query: 181 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240 P A + + R A S R +CR + G + GS +P + Q+ Sbjct: 2093 PPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCR-SPGMLEPLGSSRTPMSVLQQ 2151 Query: 241 A 241 A Sbjct: 2152 A 2152 Score = 33.5 bits (75), Expect = 0.20 Identities = 50/249 (20%), Positives = 97/249 (38%), Gaps = 40/249 (16%) Query: 2 KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQ 61 + R + TR R +S + +T P+ ++ P T +RR +P + Sbjct: 1899 RSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTP---TTRRRSRSRTPPVTR 1955 Query: 62 QGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQR 121 + ++ R P ++R++ R + + + T +R + R + T +R Sbjct: 1956 RRSRSR------TPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRS----RSRTSPVTRRR 2005 Query: 122 RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRS-S 180 S +SP ++ + + P + R+ R P P++R SRS S Sbjct: 2006 SRSRTSPVTRRR---------SRSRTPPAIRRRSRSRTPLLPRKR----------SRSRS 2046 Query: 181 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240 P A ++ ++ R T+RG R+ R + R A+G+ R ++P A + Sbjct: 2047 PLAIRRRSRSRTPR-------TARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNH 2099 Query: 241 AQDREEEAA 249 + R A Sbjct: 2100 SGSRTPPVA 2108 Score = 32.0 bits (71), Expect = 0.57 Identities = 34/190 (17%), Positives = 66/190 (34%), Gaps = 20/190 (10%) Query: 2 KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQ 61 +P+ K + R SS + ++ P + GT R+GS +SP A++ Sbjct: 803 QPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANE 862 Query: 62 QGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRK------PQQPQCRPA 115 Q + + + +++ + + +P T R+ QP+ + Sbjct: 863 QSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAI 922 Query: 116 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSR--------------GHRTEKRKPQ 161 QR SGSS + + + + +P S K KP+ Sbjct: 923 ISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPE 982 Query: 162 QPQRRPAAGT 171 P R+ +G+ Sbjct: 983 TPPRQSHSGS 992 >gi|153070260 myristoylated alanine-rich protein kinase C substrate [Homo sapiens] Length = 332 Score = 54.7 bits (130), Expect = 8e-08 Identities = 58/252 (23%), Positives = 104/252 (41%), Gaps = 44/252 (17%) Query: 39 PQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSS 98 P +G + + +GS+P+AD +EE AAA A A ++ E AAAA AP + Sbjct: 47 PAAAESGAKEELQANGSAPAAD------KEEPAAAGSGAASPSAAEKGEPAAAA-APEAG 99 Query: 99 GHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSR------- 151 EK P + + G G +S ++ + E A P+P++ Sbjct: 100 ASPVEKEAPAEGEAAEPGSPTAAEGEAASAAS---STSSPKAEDGATPSPSNETPKKKKK 156 Query: 152 -----------GHRTEKRKPQQPQ----RRPAA--GTGQRRGSRSSPSADQQGAQDRE-- 192 G +K K + + PAA G + G ++ +A+ A + Sbjct: 157 RFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAA 216 Query: 193 ---EEAAAAPVPTSRGHRTEKRKRQ---QPQCRPAAGTGQRRGSRSSPSADQQRAQDREE 246 EEAAA + G E + ++ P+ PA + + + + ++++A++ Sbjct: 217 APGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPA--SDETKAAEEPSKVEEKKAEEAGA 274 Query: 247 EAAAAPAPTSSG 258 AAA AP+++G Sbjct: 275 SAAACEAPSAAG 286 Score = 46.2 bits (108), Expect = 3e-05 Identities = 52/216 (24%), Positives = 90/216 (41%), Gaps = 29/216 (13%) Query: 55 SSPSADQQGAQDREEEAAAAPAADQQRAQDR---EEEAAAAPAPTSSGHRTEKRKPQQPQ 111 S +A + A +R EAA A + + Q+ + A+PA SG K + Q Sbjct: 6 SKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESG---AKEELQANG 62 Query: 112 CRPAGGTGQRRGSGS---SPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQR--- 165 PA + +GS SPSA ++G E AAA AP + EK P + + Sbjct: 63 SAPAADKEEPAAAGSGAASPSAAEKG------EPAAAAAPEAGASPVEKEAPAEGEAAEP 116 Query: 166 -RPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGT 224 P A G+ + SS S+ + E A P P++ + +K++ + +G Sbjct: 117 GSPTAAEGEAASAASSTSSP-------KAEDGATPSPSNETPKKKKKRFSFKKSFKLSGF 169 Query: 225 GQRRGSRSS---PSADQQRAQDREEEAAAAPAPTSS 257 ++ + + A+ A+ ++EAA A ++ Sbjct: 170 SFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAA 205 Score = 45.4 bits (106), Expect = 5e-05 Identities = 48/229 (20%), Positives = 91/229 (39%), Gaps = 28/229 (12%) Query: 28 EKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREE 87 EK P + P G+ + SS S+ + E A P+ + + +++ Sbjct: 104 EKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKA-------EDGATPSPSNETPKKKKK 156 Query: 88 EAAAAPAPTSSGHRTEKRKPQ-----QPQCRPAGGTGQRRGSGSSPSADQQGAQDREE-- 140 + + SG +K K + + + A G G++ +A + GA E+ Sbjct: 157 RFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAA 216 Query: 141 ---EAAAAPAPTSRGHRTEKRKPQQ----PQRRPAAGTGQRRGSRSSPSADQQGAQDREE 193 E AAA + G ++ KPQ+ P++ PA+ + + + +++ A++ Sbjct: 217 APGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASD--ETKAAEEPSKVEEKKAEEAGA 274 Query: 194 EAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQ 242 AAA P++ G + P PAA + S+ +A Q AQ Sbjct: 275 SAAACEAPSAAGPGAPPEQEAAPAEEPAAA-----AASSACAAPSQEAQ 318 Score = 42.0 bits (97), Expect = 6e-04 Identities = 35/152 (23%), Positives = 62/152 (40%), Gaps = 8/152 (5%) Query: 52 GSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREE----EAAAAPAPTSSGHRTEKRKP 107 G +P+A+ G +D AAA AA+ A + E AAA ++G ++ KP Sbjct: 182 GEAEAPAAE--GGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKP 239 Query: 108 QQPQCRPAG--GTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQR 165 Q+ P + + + + +++ A++ AAA AP++ G + P Sbjct: 240 QEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAE 299 Query: 166 RPAAGTGQRRGSRSSPSADQQGAQDREEEAAA 197 PAA + S A + + + AA Sbjct: 300 EPAAAAASSACAAPSQEAQPECSPEAPPAEAA 331 Score = 32.0 bits (71), Expect = 0.57 Identities = 25/105 (23%), Positives = 45/105 (42%), Gaps = 5/105 (4%) Query: 44 AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA-ADQQRAQDREEEAAAAPAPTSSGHRT 102 AGG Q + A ++ E +AA P+ ++++A++ AAA AP+++G Sbjct: 230 AGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAG--- 286 Query: 103 EKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA 147 P + + PA S + + Q+ + EA A A Sbjct: 287 -PGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEA 330 >gi|38788274 bromodomain PHD finger transcription factor isoform 1 [Homo sapiens] Length = 2920 Score = 54.7 bits (130), Expect = 8e-08 Identities = 56/220 (25%), Positives = 86/220 (39%), Gaps = 26/220 (11%) Query: 44 AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTE 103 A GTG++R S SP Q QD+ A + + AQ + + +A P P +T+ Sbjct: 2232 AAGTGEQRQSKLSPQ--MQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQP-----QTQ 2284 Query: 104 KRKPQQP--QCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQ 161 + P QP Q +P T S A AQ + + AA P S + Q Sbjct: 2285 PQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQ 2344 Query: 162 QPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRP- 220 P Q R S+PS G Q + + + P+P + + QPQ +P Sbjct: 2345 SPS--------QTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQ 2396 Query: 221 --------AAGTGQRRGSRSSPSADQQRAQDREEEAAAAP 252 ++G + + SSPS Q + Q + + A P Sbjct: 2397 VQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVP 2436 Score = 34.7 bits (78), Expect = 0.088 Identities = 35/118 (29%), Positives = 43/118 (36%), Gaps = 25/118 (21%) Query: 62 QGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQR 121 +G + R + AAPAA E A AP P P P P GG R Sbjct: 2 RGRRGRPPKQPAAPAA---------ERCAPAPPPP----------PPPPTSGPIGGLRSR 42 Query: 122 -RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSR 178 RGS A Q E A + RG + +RKP P P + + RG R Sbjct: 43 HRGSSRGRWAAAQA-----EVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGGR 95 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 54.3 bits (129), Expect = 1e-07 Identities = 52/251 (20%), Positives = 97/251 (38%), Gaps = 15/251 (5%) Query: 17 ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA 76 + +EG+ E+E + +++ Q + G + P + +G + E E A P Sbjct: 2151 QDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQP--ESEGIEAPEAEGEAQPE 2208 Query: 77 ADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGT-GQRRGSGSSPSADQQGA 135 + A + EEEA P + + +P+ G T G+++GS P Sbjct: 2209 LEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESE-----GETQGEKKGS---PQVSLGDG 2260 Query: 136 QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEA 195 Q E +++P P R P +RP + TG SS Q + + Sbjct: 2261 QSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVL 2320 Query: 196 AAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRR----GSRSSPSADQQRAQDREEEAAAA 251 P ++ T +R+ + P + T ++ GSR+ + +E++A + Sbjct: 2321 GDTRSPDAKSTGTPHAERKATRMYPESSTSEQEEAPLGSRTPEQGASEGYDLQEDQALGS 2380 Query: 252 PAPTSSGHRTE 262 APT + R + Sbjct: 2381 LAPTEAVGRAD 2391 Score = 46.6 bits (109), Expect = 2e-05 Identities = 41/199 (20%), Positives = 72/199 (36%), Gaps = 12/199 (6%) Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPA 94 P+ + + QP + + + +G + ++ E A P ++ AQ+ EEEA Sbjct: 2119 PETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELE 2178 Query: 95 PTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHR 154 + + +P+ G+ + P + A + EEEA P G Sbjct: 2179 GVEAPEAEGEAQPESEGIEAPEAEGE-----AQPELEGVEAPEAEEEA----QPEPEGVE 2229 Query: 155 TEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQ 214 T + + + G+++G SP Q E +++PVP R Sbjct: 2230 TPEAEGEAQPESEGETQGEKKG---SPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGD 2286 Query: 215 QPQCRPAAGTGQRRGSRSS 233 P RP + TG SS Sbjct: 2287 TPHQRPGSQTGPSSSRASS 2305 Score = 44.3 bits (103), Expect = 1e-04 Identities = 47/242 (19%), Positives = 86/242 (35%), Gaps = 9/242 (3%) Query: 17 ESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPA 76 E+ E + ++ E P+ + + QP + + + + +GA+ +E E AA A Sbjct: 1891 ETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEA 1950 Query: 77 ADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQ 136 Q + + E+ A + + + + A G Q + Q Sbjct: 1951 EGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQ 2010 Query: 137 DREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAA 196 + EEEA P S G + K + + + G Q+ + P +D A + EEEA Sbjct: 2011 EAEEEA----QPESDGVEAQP-KSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQ 2065 Query: 197 AAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTS 256 A + + + A G Q S + A+ ++A AP + Sbjct: 2066 EAEGEVQEAEGEAHPESEDVDAQEAEGEAQ----PESEGVEAPEAEGEAQKAEGIEAPET 2121 Query: 257 SG 258 G Sbjct: 2122 EG 2123 Score = 38.5 bits (88), Expect = 0.006 Identities = 53/234 (22%), Positives = 86/234 (36%), Gaps = 29/234 (12%) Query: 46 GTGQRRGSGSSPSADQQGAQ--DREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTE 103 G G +G G D +G+Q +R+++ A AQ+R E + TS+G Sbjct: 1731 GPGLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQER--EGKTHNSETSAGSELG 1788 Query: 104 KRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEE------AAAAPAPTSRGH-RTE 156 + + + G TG +GSG + + A +++ A AP + G + E Sbjct: 1789 EAEQEGEGISERGETG-GQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPE 1847 Query: 157 KRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAP------------VPTSR 204 + P+ A G Q + P ++ A + E EA P S Sbjct: 1848 SEGVEAPE---AEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESE 1904 Query: 205 G-HRTEKRKRQQPQCRPA-AGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTS 256 G E K QP+ A + S A+ Q A++ +EA P S Sbjct: 1905 GAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPES 1958 Score = 34.3 bits (77), Expect = 0.12 Identities = 62/247 (25%), Positives = 83/247 (33%), Gaps = 36/247 (14%) Query: 29 KTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEE 88 K P P+++ CQ G+ R SS + Q R + + P+ QD Sbjct: 684 KQVPRPPERRRACQD--GSVPRYSGSSSSTRTQASGNLRPPSSGSLPS------QDLLGT 735 Query: 89 AAAAPAPTSSGHRTEKRKPQQ-PQCRPAGGTGQRRGSGS------SPSADQQGAQDREEE 141 ++A P P P AG G R S + S S + GA EE Sbjct: 736 SSATVTPAVHSDFVSGVSPHNAPSAGWAGDAGSRTCSPAPIPPHTSDSCSKSGAASLGEE 795 Query: 142 AAAAPAPTSRGHRTEKRKPQQPQ-RRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPV 200 A P P+S P Q RP G G S Q G Q +EA P Sbjct: 796 ARDTPQPSS---------PLVLQVGRPEQGA---VGPHRSHCCSQPGTQP-AQEAQRGPS 842 Query: 201 PTS-----RGHRTEKRKRQQPQCRPAA--GTGQRRGSRSSPSADQQRAQDREEEAAAAPA 253 P + R T R R PQ R ++ TG S + + R+ +P Sbjct: 843 PEASWLCGRYCPTPPRGRPCPQRRSSSCGSTGSSHQSTARGPGGSPQEGTRQPGPTPSPG 902 Query: 254 PTSSGHR 260 P S R Sbjct: 903 PNSGASR 909 >gi|74272284 membrane associated guanylate kinase, WW and PDZ domain containing 1 isoform c [Homo sapiens] Length = 1462 Score = 53.5 bits (127), Expect = 2e-07 Identities = 44/179 (24%), Positives = 76/179 (42%), Gaps = 12/179 (6%) Query: 46 GTGQRRGSGSSPSADQ--QGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPT-SSGHRT 102 GT ++ SG+ D+ +G +D + E AAA ++R+ ++ E + T + Sbjct: 1284 GTSRKPDSGACRPKDRAPEGRRDAQAERAAAANGPKRRSPEKRREGTRSADNTLERREKH 1343 Query: 103 EKRKPQQPQCRPAGGTGQRRGSGSS---PSADQQGAQDREEEAAAAPAPTSRGHRTEKRK 159 EKR+ P+ R +RR S S ++ Q R E +P R T++R+ Sbjct: 1344 EKRRDVSPERRRERSPTRRRDGSPSRRRRSLERLLEQRRSPERRRGGSPERRAKSTDRRR 1403 Query: 160 PQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQC 218 + P+RR +R D+ ++REE S H E+R+R +C Sbjct: 1404 ARSPERRRERSLDKRN------REDRASHREREEANLKQDAGRSSRHPPEQRRRPYKEC 1456 Score = 40.8 bits (94), Expect = 0.001 Identities = 60/257 (23%), Positives = 96/257 (37%), Gaps = 32/257 (12%) Query: 21 GDQWLE--NEKTKPLRPQQQPQCQPAGGTGQR----RGSGSSPSADQQGAQDREEEAAAA 74 GD+ LE E TK ++ + + GG R RG GS P D + DR A Sbjct: 1167 GDEILEINGETTKNMKHSRAIELIKNGGRRVRLFLKRGDGSVPEYDP--SSDRHGPATGP 1224 Query: 75 PAADQQRA-QDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQ- 132 + RA DR + + + H++ ++ R G+ R P+ Sbjct: 1225 QGVPEVRAGPDRRQHPSLESSYPPDLHKSSPHGEKRAHARDPKGS---REYSRQPNEHHT 1281 Query: 133 -QGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDR 191 G + + A P + E R+ Q +R AA +RR SP ++G + Sbjct: 1282 WNGTSRKPDSGACRP----KDRAPEGRRDAQAERAAAANGPKRR----SPEKRREGTR-- 1331 Query: 192 EEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRG---SRSSPSADQQRAQDREEEA 248 +A R + EKR+ P+ R +RR SR S ++ Q R E Sbjct: 1332 -----SADNTLERREKHEKRRDVSPERRRERSPTRRRDGSPSRRRRSLERLLEQRRSPER 1386 Query: 249 AAAPAPTSSGHRTEKRK 265 +P T++R+ Sbjct: 1387 RRGGSPERRAKSTDRRR 1403 Score = 30.8 bits (68), Expect = 1.3 Identities = 25/113 (22%), Positives = 44/113 (38%), Gaps = 5/113 (4%) Query: 5 QKEQDTRLRKLRESS-----EGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSA 59 +K +D + RE S +G + L Q++ + GG+ +RR + Sbjct: 1344 EKRRDVSPERRRERSPTRRRDGSPSRRRRSLERLLEQRRSPERRRGGSPERRAKSTDRRR 1403 Query: 60 DQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQC 112 + + RE D+ ++REE A SS H E+R+ +C Sbjct: 1404 ARSPERRRERSLDKRNREDRASHREREEANLKQDAGRSSRHPPEQRRRPYKEC 1456 >gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B subunit [Homo sapiens] Length = 2339 Score = 52.0 bits (123), Expect = 5e-07 Identities = 61/238 (25%), Positives = 88/238 (36%), Gaps = 46/238 (19%) Query: 5 QKEQDTRLRKLRESSEG-------DQWLENEKTKPLRPQQQPQCQ--------------P 43 Q+ RL+ LR S E ++ L T+ LRP + P Sbjct: 770 QRASQLRLQNLRASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGP 829 Query: 44 AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAA-DQQRAQDREEEAAAAPAPTSSGHRT 102 GG + + + D R + PAA DQ RA+ + E+ G R Sbjct: 830 VGGKARPEAAEAPEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESG------EPGARE 883 Query: 103 EKRKPQQPQCRPAGGTGQ---RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRK 159 E+ +P + + A G + RG G P ++ + E AA P R HR + Sbjct: 884 ERPRPHRSHSKEAAGPPEARSERGRGPGPEGGRRHHRRGSPEEAAEREP--RRHRAHRH- 940 Query: 160 PQQPQRRPAAGTGQRRG-SRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQP 216 Q P + A G+RR R P A + A+ EE A R HR R + QP Sbjct: 941 -QDPSKECAGAKGERRARHRGGPRAGPREAESGEEPA--------RRHRA--RHKAQP 987 >gi|78042577 MAP7 domain containing 1 [Homo sapiens] Length = 841 Score = 51.2 bits (121), Expect = 9e-07 Identities = 64/267 (23%), Positives = 97/267 (36%), Gaps = 49/267 (18%) Query: 14 KLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAA 73 K R SS W +P P P P + S +A +G R+EEA Sbjct: 464 KARPSSPSTSW-----HRPASPCPSPG--PGHTLPPKPPSPRGTTASPKGRVRRKEEAKE 516 Query: 74 APAA--------DQQRAQDREEEAAAA---PAPTSSGHRTEKRKPQQPQCRPAGG----T 118 +P+A ++RA + +E AA A P+P S +K Q P P + Sbjct: 517 SPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTS 576 Query: 119 GQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSR 178 +PS G DREE EKR+ + QR + + R Sbjct: 577 PPAPAPPVTPSKPMAGTTDREEATRLL---------AEKRRQAREQREREEQERRLQAER 627 Query: 179 SSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQ 238 ++Q A++ E A E R+R++ + R A Q +Q Sbjct: 628 DKRMREEQLAREAEARAE---------REAEARRREEQEAREKAQAEQE---------EQ 669 Query: 239 QRAQDREEEAAAAPAPTSSGHRTEKRK 265 +R Q ++EEA A + R E+ K Sbjct: 670 ERLQKQKEEAEARSREEAERQRLEREK 696 Score = 42.4 bits (98), Expect = 4e-04 Identities = 57/246 (23%), Positives = 93/246 (37%), Gaps = 55/246 (22%) Query: 43 PAGGTGQRRGS--GSSPSADQQGAQ-------DREEEAAAAPAADQQRAQDREEEAAAAP 93 P G Q RG G P+ + GA DR +AA P + A+A+P Sbjct: 318 PRNGRDQGRGCDPGRGPTWGRAGASLARGPQPDRTHPSAAVPVCPRS--------ASASP 369 Query: 94 APTSSGHRTEKRKPQQPQCRPAGGTGQRR--GSGSSPS----------ADQQGAQDREEE 141 S R+ R C PAG G+RR +G SP+ ++ +D+E E Sbjct: 370 LTPCSVTRSVHR------CAPAGERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERE 423 Query: 142 AAAAPAPTSRGHRTEKRK--PQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAP 199 + +R +KR+ P P+ R +A T +S + + A+P Sbjct: 424 NEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKA---RPSSPSTSWHRPASP 480 Query: 200 VPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGH 259 P+ T K P RG+ +SP +R +EEA +P+ Sbjct: 481 CPSPGPGHTLPPKPPSP-----------RGTTASPKGRVRR----KEEAKESPSAAGPED 525 Query: 260 RTEKRK 265 +++ ++ Sbjct: 526 KSQSKR 531 Score = 41.2 bits (95), Expect = 0.001 Identities = 52/244 (21%), Positives = 95/244 (38%), Gaps = 46/244 (18%) Query: 40 QCQPAGGTGQRR--GSGSSPSA------------DQQGAQDREEEAAAAPAADQQRAQDR 85 +C PAG G+RR +G SP+ ++ ++RE E + A ++ + R Sbjct: 381 RCAPAGERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKR 440 Query: 86 EEEAAAAPAPTSSGHRTE-----KRKPQQPQCR--------PAGGTGQR--------RGS 124 + A+ A S+ +E K +P P P+ G G RG+ Sbjct: 441 QSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGT 500 Query: 125 GSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSAD 184 +SP +G R+EEA +P+ +++ ++ ++ AA SP+ Sbjct: 501 TASP----KGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPT-- 554 Query: 185 QQGAQDREEEAAAAPVPTSRGHRTEKRKRQQP--QCRPAAGTGQRRGSRSSPSADQQRAQ 242 ++E A PT T P +P AGT R + + +++A+ Sbjct: 555 ---PAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAR 611 Query: 243 DREE 246 ++ E Sbjct: 612 EQRE 615 Score = 37.4 bits (85), Expect = 0.014 Identities = 40/176 (22%), Positives = 73/176 (41%), Gaps = 26/176 (14%) Query: 7 EQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQD 66 E+ + R+ RE E ++ L+ E+ K +R +Q + + R + + ++ + Sbjct: 605 EKRRQAREQREREEQERRLQAERDKRMREEQLAR------EAEARAEREAEARRREEQEA 658 Query: 67 REEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRK--PQQPQCRP---------- 114 RE+ A A +Q+R Q ++EEA A + R E+ K QQ Q R Sbjct: 659 REK--AQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIM 716 Query: 115 ----AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRK--PQQPQ 164 + + S A+ G+ +A A +P + +K + PQ+PQ Sbjct: 717 KRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEPIPQEPQ 772 Score = 33.9 bits (76), Expect = 0.15 Identities = 41/195 (21%), Positives = 66/195 (33%), Gaps = 19/195 (9%) Query: 56 SPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPA 115 +PS G DREE +Q + RE E +KR ++ R A Sbjct: 585 TPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAER----DKRMREEQLAREA 640 Query: 116 GGTGQRRGSGSSPSADQQGAQDREEEAAA--APAPTSRGHRTEKRKPQQPQRRPAAGTGQ 173 +R A+ REE+ A A A R +K+K + R Q Sbjct: 641 EARAEREAE----------ARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQ 690 Query: 174 RRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQ---RRGS 230 R +Q Q+R + T + +E +++Q + A G+ + Sbjct: 691 RLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVE 750 Query: 231 RSSPSADQQRAQDRE 245 SP ++ Q E Sbjct: 751 ARSPGLQKEAVQKEE 765 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 50.8 bits (120), Expect = 1e-06 Identities = 50/265 (18%), Positives = 97/265 (36%), Gaps = 4/265 (1%) Query: 2 KPRQKEQDTRLRKLRE-SSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60 K R +++D + R+ E ++ + E+ + ++ Q + T + G D Sbjct: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144 Query: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ 120 Q ++R+ +A R + R+ E +R E+R+ ++ Q T Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERER-QREKENKTED 203 Query: 121 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSS 180 R ++ + E R +TE+ + +Q +R A+ R Sbjct: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263 Query: 181 PSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240 D+ +DR ++ R RTE R R+ + R +R R+ +++R Sbjct: 264 RERDRDRDRDRRQKERERQTDRKRQRRTE-RDRETERKRERQRERERERERNR-KRERER 321 Query: 241 AQDREEEAAAAPAPTSSGHRTEKRK 265 ++RE E R KRK Sbjct: 322 ERERERERQRETERDREKERERKRK 346 Score = 48.5 bits (114), Expect = 6e-06 Identities = 54/268 (20%), Positives = 108/268 (40%), Gaps = 12/268 (4%) Query: 4 RQKEQDTRLRKLRESSEGDQW-LENEKTKPLRPQQQPQCQPAGGTGQRRGS-GSSPSADQ 61 +++E+ T + R++ Q E EK + R +++ Q + T R G ++ Sbjct: 157 KERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERER 216 Query: 62 QGAQDREEEAAAAPAADQQRA--QDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTG 119 + + E + D+QR ++RE++A A R ++R+ ++ + R Sbjct: 217 ETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQ 276 Query: 120 QRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRS 179 + R + ++ +DRE E R RK ++ + R QR R Sbjct: 277 KERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERD 336 Query: 180 SPSADQQGAQDREEEAAAAPVPTSR-GHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQ 238 ++ + + E T R G R +R+R++ + R R+ +R ++ Sbjct: 337 REKERERKRKRQTEMDRERNRQTGREGRRQAERERERERER------DRQSAREREERER 390 Query: 239 QRAQDREEEAAAAPAPTSSGHR-TEKRK 265 R +DR++E G R TEK++ Sbjct: 391 DRDRDRQKERERQTEKDRDGQRETEKQR 418 Score = 45.8 bits (107), Expect = 4e-05 Identities = 54/264 (20%), Positives = 96/264 (36%), Gaps = 16/264 (6%) Query: 2 KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQ 61 + R+KE T R E ++ E E + Q + T + R A++ Sbjct: 193 RQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERER----EKQAER 248 Query: 62 QGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQR 121 + A +RE E ++ R +DR+ T + + ++ + + + Sbjct: 249 ERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERE 308 Query: 122 RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSP 181 R + +++ ++RE E R KRK Q R R G R Sbjct: 309 RERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRR--- 365 Query: 182 SADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRA 241 A+++ ++RE + +A R R R R + + R R G R + ++R Sbjct: 366 QAERERERERERDRQSA---REREERERDRDRDRQKERERQTEKDRDGQRET-EKQRERE 421 Query: 242 QDREEEAAAAPAPTSSGHRTEKRK 265 +DRE E G EK+K Sbjct: 422 KDRESERG-----RERGREREKQK 440 Score = 42.4 bits (98), Expect = 4e-04 Identities = 50/249 (20%), Positives = 94/249 (37%), Gaps = 24/249 (9%) Query: 2 KPRQKEQDTR--LRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSA 59 +P +E R L + + ++GD N + + R +++ Q + Sbjct: 30 RPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTER--------------ET 75 Query: 60 DQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTG 119 D++ + RE++ ++R +DRE+E R ++R Q+ + R G Sbjct: 76 DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135 Query: 120 QRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRS 179 +R G D Q ++R+ +A + R + + + + R Q R R Sbjct: 136 ER---GRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERE 192 Query: 180 SPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRS-SPSADQ 238 + +DR E +RKRQ + R QR+ R A++ Sbjct: 193 RQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR----QRKTEREREKQAER 248 Query: 239 QRAQDREEE 247 +RA +RE E Sbjct: 249 ERASERETE 257 Score = 35.8 bits (81), Expect = 0.040 Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 6/131 (4%) Query: 121 RRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRS- 179 RR GS S ++G ++A +R E+R+ ++ R +RR + Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87 Query: 180 --SPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSAD 237 ++ +DRE+E R ++R RQ+ + R G+R R + D Sbjct: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQT---D 144 Query: 238 QQRAQDREEEA 248 QR ++R+ +A Sbjct: 145 GQRERERQRDA 155 Score = 31.6 bits (70), Expect = 0.75 Identities = 25/145 (17%), Positives = 52/145 (35%), Gaps = 5/145 (3%) Query: 104 KRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQP 163 +R+P + G GQ ++ ++RE + E+R+ + Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87 Query: 164 QRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAG 223 R+ + R + +++ DRE + + R + +R+ + R Sbjct: 88 HRK----RDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQT 143 Query: 224 TGQRRGSRS-SPSADQQRAQDREEE 247 GQR R +++R DRE + Sbjct: 144 DGQRERERQRDAEKERERQTDRERQ 168 Score = 30.4 bits (67), Expect = 1.7 Identities = 40/183 (21%), Positives = 73/183 (39%), Gaps = 24/183 (13%) Query: 2 KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQ--------QPQCQPAGGTGQRRGS 53 + R++E+D + + RE E D+ + +K + + ++ + Q + RG Sbjct: 371 RERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGR 430 Query: 54 GSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCR 113 ++Q ++R+ E A +QR + P P ++ + P R Sbjct: 431 ERGREREKQKGRERDRERQTDRQAGRQR---KRSTLYVNPPPRTARSGVVQSDPN----R 483 Query: 114 PAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRK--PQQPQRRPAAGT 171 P G + SSP D + A R PA SRG +R+ P+ ++R G Sbjct: 484 PTRGIRWK----SSPE-DPKAASTR--FPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGE 536 Query: 172 GQR 174 G+R Sbjct: 537 GRR 539 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 50.8 bits (120), Expect = 1e-06 Identities = 56/248 (22%), Positives = 97/248 (39%), Gaps = 42/248 (16%) Query: 46 GTGQRRGSGSSPSADQQGAQDREEEA----AAAPAADQQRAQDREEEAAAAPAPTSSGHR 101 GT +R +P + + EE+ AAA + Q+R R+ + +++ + +SS Sbjct: 444 GTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSE 503 Query: 102 TEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEA------------------A 143 E+ K + G G+RR S SA + ++E + + Sbjct: 504 DERPKRSHVK---NGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS 560 Query: 144 AAPAPTSRGHRT-----EKRKPQQPQRRPAAGTG------QRRGSRSSPSADQQGAQDRE 192 +PAP R RT +R P P RR + QRR S S P + + Sbjct: 561 PSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP 620 Query: 193 EEAAAAPVPTSR---GHRTEKRKRQQPQCR---PAAGTGQRRGSRSSPSADQQRAQDREE 246 + A+P P + H ++R P + P+ + R+GS S S + R+ + Sbjct: 621 PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNK 680 Query: 247 EAAAAPAP 254 + +P P Sbjct: 681 RHSPSPRP 688 Score = 47.0 bits (110), Expect = 2e-05 Identities = 54/291 (18%), Positives = 120/291 (41%), Gaps = 31/291 (10%) Query: 3 PRQKEQDTRLRK--LRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSAD 60 P E ++++ ++E++ L+ K +P+ ++P P + + + + Sbjct: 221 PELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPS--PEKNSKKEKEKEKTRPRS 278 Query: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTE--------KRKPQQPQC 112 + ++ R + +P+ + R + R + +P S R +R P P+ Sbjct: 279 RSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRH 338 Query: 113 RPAGGTGQRR--------GSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQ 164 R + +RR GS SS S+ + + ++ + P + P + + Sbjct: 339 RRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRR 398 Query: 165 RRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTS----RGHRTEKRKRQQPQCRP 220 RP+ +R SP+ QQ + R+ + +P TS + TEKR+ P +P Sbjct: 399 HRPSPPATPPPKTRHSPT-PQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457 Query: 221 ----AAGTGQRRGSR--SSPSADQQRAQDREEEAAAAPAPTSSGHRTEKRK 265 + + + +G + ++ S Q+R R+ + +++ + +SS E+ K Sbjct: 458 RKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPK 508 Score = 40.0 bits (92), Expect = 0.002 Identities = 45/216 (20%), Positives = 76/216 (35%), Gaps = 23/216 (10%) Query: 49 QRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQ 108 +RR S S P + + + + + + R A +P P + +P+ Sbjct: 632 KRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNK--RHSPSPRPR 689 Query: 109 QPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPA 168 PQ + RRG+ SSP Q +P+P++R R R P+ + + A Sbjct: 690 APQTS-SSPPPVRRGASSSPQRRQ------------SPSPSTRPIRRVSRTPEPKKIKKA 736 Query: 169 AGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRR 228 A + R S S G+ E A P P S + Q P + ++ Sbjct: 737 ASPSPQSVRRVSSSRSVSGSP--EPAAKKPPAPPS------PVQSQSPSTNWSPAVPVKK 788 Query: 229 GSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKR 264 +PS R D+E H+ +K+ Sbjct: 789 AKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKK 824 Score = 37.7 bits (86), Expect = 0.010 Identities = 40/226 (17%), Positives = 79/226 (34%), Gaps = 14/226 (6%) Query: 49 QRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQ 108 +RR S S + + R P + + + +P HR Sbjct: 348 RRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATP 407 Query: 109 QPQCR------PAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ 162 P+ R + T + R S S + + + E +P+P + + E + ++ Sbjct: 408 PPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEE 467 Query: 163 PQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGH----RTEKRKRQQPQC 218 + A + R +QQ + D +++ R H +R+R P Sbjct: 468 DKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS- 526 Query: 219 RPAAGTGQRRGSRSSPSADQQRAQD---REEEAAAAPAPTSSGHRT 261 R A+ + ++R +SP ++R+ + +PAP RT Sbjct: 527 RSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRT 572 Score = 37.7 bits (86), Expect = 0.010 Identities = 38/237 (16%), Positives = 86/237 (36%), Gaps = 21/237 (8%) Query: 28 EKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREE 87 +++ P+ ++ P + GSSPS + A+ + +P+ + R Sbjct: 643 QRSSPVTKRRSPSLS------SKHRKGSSPSRSTREARSPQPNKRHSPSP-----RPRAP 691 Query: 88 EAAAAPAPTSSGHRT--EKRKPQQPQCRPAGGTGQ-------RRGSGSSPSADQQGAQDR 138 + +++P P G + ++R+ P RP + ++ + SP + ++ + R Sbjct: 692 QTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSR 751 Query: 139 EEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAA 198 + PA + Q P + ++ +PS D+E Sbjct: 752 SVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKK 811 Query: 199 PVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQD-REEEAAAAPAP 254 + H+ +K+ ++ + + + +P+A +EE AAP P Sbjct: 812 KKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEP 868 Score = 30.4 bits (67), Expect = 1.7 Identities = 30/161 (18%), Positives = 60/161 (37%), Gaps = 24/161 (14%) Query: 120 QRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRS 179 ++ S D+ E+E++ SR R K + P+RR + +R+ S S Sbjct: 139 EKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHS 198 Query: 180 ------SPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQ------- 226 + S A +++E+ P P+ K ++P + A T Sbjct: 199 RSPRHRTKSRSPSPAPEKKEKTPELPEPSV--------KVKEPSVQEATSTSDILKVPKP 250 Query: 227 ---RRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKR 264 SP + ++ +++E+ + + + S RT R Sbjct: 251 EPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSR 291 >gi|71274172 ankyrin repeat domain 56 [Homo sapiens] Length = 793 Score = 50.8 bits (120), Expect = 1e-06 Identities = 65/243 (26%), Positives = 84/243 (34%), Gaps = 57/243 (23%) Query: 34 RPQQQPQCQPAGG-------TGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDRE 86 RP++ P P+ G G RRG P Q + RE+E PA RA D Sbjct: 88 RPREPPAAAPSAGGAAPCSPRGARRGE---PPQQQPRRRRREKEPEEEPAGAAARAAD-- 142 Query: 87 EEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSP---SADQQGAQDREEEAA 143 AA P S R P G G + G P +A GAQ R AA Sbjct: 143 --AACNGLPGSDSRRA-----------PGKGGGSKGSPGQRPPVPAAAAAGAQARASCAA 189 Query: 144 AAPAPTSRGHRTEKR---KPQQPQRRPAAGTGQRRGSRSSPSADQQGA-QDREEEAAAAP 199 A + P + P + T + + +R+ P+ D +GA ++REE A A P Sbjct: 190 AKTQGRCCWECLQNNLAVLPGELGALPHSATAEEKPARALPAQDDRGASREREEGALAEP 249 Query: 200 VPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGH 259 P PA SP A + A R A P P G Sbjct: 250 APV-----------------PAVA--------HSPPATVEAATSRASPPALLPGPAPRGD 284 Query: 260 RTE 262 R E Sbjct: 285 RPE 287 >gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] Length = 2285 Score = 50.4 bits (119), Expect = 2e-06 Identities = 59/239 (24%), Positives = 90/239 (37%), Gaps = 33/239 (13%) Query: 46 GTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKR 105 G Q G+G P AD AAAA AA AQ R A +P + G + R Sbjct: 318 GGPQDGGAGKGP-ADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLAR 376 Query: 106 KPQQPQCRPAGGTGQRRG---SGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ 162 PQ P G+ R G++P + QQG ++ P G +T +R P Sbjct: 377 TPQPSS--PMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPG-QPYGSQTPQRYPMT 433 Query: 163 PQRRPAAGTGQRRGSRSSPSADQQG-----------------AQDREEEAAAAPVPTSRG 205 Q R + G ++ P QQG ++++ + P S+ Sbjct: 434 MQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQT 493 Query: 206 HRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKR 264 + +QQPQ +P + S P QQ +Q ++ +PAP S T ++ Sbjct: 494 PHAQPSYQQQPQSQPP------QLQSSQPPYSQQPSQPPHQQ---SPAPYPSQQSTTQQ 543 Score = 47.0 bits (110), Expect = 2e-05 Identities = 53/230 (23%), Positives = 90/230 (39%), Gaps = 25/230 (10%) Query: 28 EKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG-AQDREEEAAAAPAADQQRAQDRE 86 + + P+ + + QP GGT PS QQG + + P Q R Sbjct: 379 QPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA 438 Query: 87 EEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAP 146 + A + T ++ P Q P+ G GQ+ G +P +QQ ++++ + Sbjct: 439 QSAMGGLSYT-------QQIPPYGQQGPS-GYGQQ---GQTPYYNQQSPHPQQQQPPYSQ 487 Query: 147 APTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGH 206 P S+ + QQPQ +P + S P QQ +Q ++ + AP P+ + Sbjct: 488 QPPSQTPHAQPSYQQQPQSQPP------QLQSSQPPYSQQPSQPPHQQ-SPAPYPSQQST 540 Query: 207 RTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTS 256 + + Q P +P A + ++ QQ A + AA P P S Sbjct: 541 TQQHPQSQPPYSQPQAQSPYQQ------QQPQQPAPSTLSQQAAYPQPQS 584 Score = 40.0 bits (92), Expect = 0.002 Identities = 41/169 (24%), Positives = 65/169 (38%), Gaps = 24/169 (14%) Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPA 94 P Q Q P + + PS QQ + ++ P QQ +Q +++ PA Sbjct: 476 PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQS---PA 532 Query: 95 PTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHR 154 P S T + Q PQ +P P + Q +++ PAP++ + Sbjct: 533 PYPSQQSTTQ---QHPQSQP-------------PYSQPQAQSPYQQQQPQQPAPSTLSQQ 576 Query: 155 TEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTS 203 +PQ Q + A + QR S D G+Q A++AP TS Sbjct: 577 AAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQ-----ASSAPSMTS 620 Score = 38.5 bits (88), Expect = 0.006 Identities = 55/205 (26%), Positives = 69/205 (33%), Gaps = 30/205 (14%) Query: 59 ADQQGAQDREEEAAAAPAADQ---QRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPA 115 A+QQ ++ EAAAA AA++ + A +E E A P G + Sbjct: 27 AEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESN-----G 81 Query: 116 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRR 175 GG G GSG P A+ + A P P + TE P G G Sbjct: 82 GGGGGGAGSGGGPGAE---PDLKNSNGNAGPRPALNNNLTEP---------PGGGGG--- 126 Query: 176 GSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPS 235 GS A A AAA P P + R AA Q+ G + SP Sbjct: 127 GSSDGVGAPPHSA------AAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180 Query: 236 -ADQQRAQDREEEAAAAPAPTSSGH 259 A Q E A P S H Sbjct: 181 LAALQSGGGGGLEPYAGPQQNSHDH 205 Score = 28.1 bits (61), Expect = 8.3 Identities = 43/172 (25%), Positives = 58/172 (33%), Gaps = 34/172 (19%) Query: 89 AAAAPAPTSSGHR------TEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEA 142 A APA SS +E +K +Q Q AG G+ + ++ + + A +E E Sbjct: 3 AQVAPAAASSLGNPPPPPPSELKKAEQQQREEAG--GEAAAAAAAERGEMKAAAGQESEG 60 Query: 143 AAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPT 202 A P G ++ Q G G GS P A+ + A P P Sbjct: 61 PAVGPPQPLG-----KELQDGAESNGGGGGGGAGSGGGPGAE---PDLKNSNGNAGPRPA 112 Query: 203 SRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAP 254 + TE P G G GS A A AAA P P Sbjct: 113 LNNNLTEP---------PGGGGG---GSSDGVGAPPHSA------AAALPPP 146 >gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] Length = 2068 Score = 50.4 bits (119), Expect = 2e-06 Identities = 59/239 (24%), Positives = 90/239 (37%), Gaps = 33/239 (13%) Query: 46 GTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKR 105 G Q G+G P AD AAAA AA AQ R A +P + G + R Sbjct: 318 GGPQDGGAGKGP-ADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLAR 376 Query: 106 KPQQPQCRPAGGTGQRRG---SGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ 162 PQ P G+ R G++P + QQG ++ P G +T +R P Sbjct: 377 TPQPSS--PMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPG-QPYGSQTPQRYPMT 433 Query: 163 PQRRPAAGTGQRRGSRSSPSADQQG-----------------AQDREEEAAAAPVPTSRG 205 Q R + G ++ P QQG ++++ + P S+ Sbjct: 434 MQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQT 493 Query: 206 HRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKR 264 + +QQPQ +P + S P QQ +Q ++ +PAP S T ++ Sbjct: 494 PHAQPSYQQQPQSQPP------QLQSSQPPYSQQPSQPPHQQ---SPAPYPSQQSTTQQ 543 Score = 47.0 bits (110), Expect = 2e-05 Identities = 53/230 (23%), Positives = 90/230 (39%), Gaps = 25/230 (10%) Query: 28 EKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG-AQDREEEAAAAPAADQQRAQDRE 86 + + P+ + + QP GGT PS QQG + + P Q R Sbjct: 379 QPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA 438 Query: 87 EEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAP 146 + A + T ++ P Q P+ G GQ+ G +P +QQ ++++ + Sbjct: 439 QSAMGGLSYT-------QQIPPYGQQGPS-GYGQQ---GQTPYYNQQSPHPQQQQPPYSQ 487 Query: 147 APTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGH 206 P S+ + QQPQ +P + S P QQ +Q ++ + AP P+ + Sbjct: 488 QPPSQTPHAQPSYQQQPQSQPP------QLQSSQPPYSQQPSQPPHQQ-SPAPYPSQQST 540 Query: 207 RTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTS 256 + + Q P +P A + ++ QQ A + AA P P S Sbjct: 541 TQQHPQSQPPYSQPQAQSPYQQ------QQPQQPAPSTLSQQAAYPQPQS 584 Score = 40.0 bits (92), Expect = 0.002 Identities = 41/169 (24%), Positives = 65/169 (38%), Gaps = 24/169 (14%) Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPA 94 P Q Q P + + PS QQ + ++ P QQ +Q +++ PA Sbjct: 476 PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQS---PA 532 Query: 95 PTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHR 154 P S T + Q PQ +P P + Q +++ PAP++ + Sbjct: 533 PYPSQQSTTQ---QHPQSQP-------------PYSQPQAQSPYQQQQPQQPAPSTLSQQ 576 Query: 155 TEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTS 203 +PQ Q + A + QR S D G+Q A++AP TS Sbjct: 577 AAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQ-----ASSAPSMTS 620 Score = 38.5 bits (88), Expect = 0.006 Identities = 55/205 (26%), Positives = 69/205 (33%), Gaps = 30/205 (14%) Query: 59 ADQQGAQDREEEAAAAPAADQ---QRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPA 115 A+QQ ++ EAAAA AA++ + A +E E A P G + Sbjct: 27 AEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESN-----G 81 Query: 116 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRR 175 GG G GSG P A+ + A P P + TE P G G Sbjct: 82 GGGGGGAGSGGGPGAE---PDLKNSNGNAGPRPALNNNLTEP---------PGGGGG--- 126 Query: 176 GSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPS 235 GS A A AAA P P + R AA Q+ G + SP Sbjct: 127 GSSDGVGAPPHSA------AAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180 Query: 236 -ADQQRAQDREEEAAAAPAPTSSGH 259 A Q E A P S H Sbjct: 181 LAALQSGGGGGLEPYAGPQQNSHDH 205 Score = 28.1 bits (61), Expect = 8.3 Identities = 43/172 (25%), Positives = 58/172 (33%), Gaps = 34/172 (19%) Query: 89 AAAAPAPTSSGHR------TEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEA 142 A APA SS +E +K +Q Q AG G+ + ++ + + A +E E Sbjct: 3 AQVAPAAASSLGNPPPPPPSELKKAEQQQREEAG--GEAAAAAAAERGEMKAAAGQESEG 60 Query: 143 AAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPT 202 A P G ++ Q G G GS P A+ + A P P Sbjct: 61 PAVGPPQPLG-----KELQDGAESNGGGGGGGAGSGGGPGAE---PDLKNSNGNAGPRPA 112 Query: 203 SRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAP 254 + TE P G G GS A A AAA P P Sbjct: 113 LNNNLTEP---------PGGGGG---GSSDGVGAPPHSA------AAALPPP 146 >gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] Length = 1007 Score = 50.4 bits (119), Expect = 2e-06 Identities = 53/255 (20%), Positives = 113/255 (44%), Gaps = 15/255 (5%) Query: 2 KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQ-PAGGTGQRRGSGSSPSAD 60 K R KE+ TR R ++ S+G + EKT + +++ + + P+ + + + S S Sbjct: 185 KSRSKER-TRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPT 243 Query: 61 QQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ 120 + + A +P D+ + +D+ + +P + R+ R + G + Sbjct: 244 LRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSK 303 Query: 121 RRGSGSSPSADQQGAQDREEEAAAAP---APTSRGHRTEKRKPQQPQRRPAAGTGQRRGS 177 R S S ++ D+E++ +P A + + +R+ R+P + +R + R S Sbjct: 304 DRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKS 363 Query: 178 RSSPSA---DQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSP 234 R S S D++ Q + +P ++ R+ +RKR++P+ R + R+ P Sbjct: 364 RRSRSPLLNDRRSKQSKSPSRTLSPGRRAKS-RSLERKRREPERR------RLSSPRTRP 416 Query: 235 SADQQRAQDREEEAA 249 D ++R ++A+ Sbjct: 417 RDDILSRRERSKDAS 431 Score = 44.3 bits (103), Expect = 1e-04 Identities = 41/191 (21%), Positives = 81/191 (42%), Gaps = 16/191 (8%) Query: 81 RAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREE 140 R++ +E + + +P+ S + + RK + P R + ++ G SP+ D+ +D+ + Sbjct: 214 RSKSKERKKSKSPSKRSKS-QDQARKSKSPTLRRR--SQEKIGKARSPTDDKVKIEDKSK 270 Query: 141 EAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPV 200 +P R+ R + G + R SRS ++ D+E++ P+ Sbjct: 271 SKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKK----PI 326 Query: 201 PTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR------AQDREEEAAAAPAP 254 + + ++ + P RP G +R S S D+ R DR + + +P+ Sbjct: 327 KSPSKDASSGKENRSPSRRP--GRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSR 384 Query: 255 T-SSGHRTEKR 264 T S G R + R Sbjct: 385 TLSPGRRAKSR 395 Score = 34.7 bits (78), Expect = 0.088 Identities = 49/216 (22%), Positives = 78/216 (36%), Gaps = 45/216 (20%) Query: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG 63 R K +D R R S+ +E K +P + P + G R SPS + G Sbjct: 299 RGKSKDRRSRSKERKSK-----RSETDKEKKPIKSPSKDASSGKENR-----SPSR-RPG 347 Query: 64 AQDREEEAAAAPAADQQRAQ-----DREEEAAAAPAPT-SSGHRT------------EKR 105 + + P +R++ DR + + +P+ T S G R E+R Sbjct: 348 RSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERR 407 Query: 106 KPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAA------APAPTSRGHRTEKRK 159 + P+ RP RR S + + R + +P SR R R Sbjct: 408 RLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRS 467 Query: 160 PQQP----------QRRPAAGTGQRRGSRSSPSADQ 185 P++ +RR + G+RR SRS D+ Sbjct: 468 PRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDK 503 >gi|239750916 PREDICTED: similar to hCG1803335 [Homo sapiens] Length = 246 Score = 50.1 bits (118), Expect = 2e-06 Identities = 50/215 (23%), Positives = 78/215 (36%), Gaps = 26/215 (12%) Query: 58 SADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQ-----QPQC 112 S Q+ A+ E R R E+ P GHR R + Q QC Sbjct: 38 SLHQRSARATESVPGPQSQCQGHRVSSRATESVPGPQSQFQGHRVSARATESVPGPQSQC 97 Query: 113 RPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSR--GHRTEKRKPQQ---PQRRP 167 + + + S P + +QG + +AP P S+ GHR R + PQ Sbjct: 98 QGHRVSSRATESVPGPQSQRQGHRVSARATESAPGPQSQCQGHRVSARATESVPGPQ--- 154 Query: 168 AAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQR 227 QR+G R S R E+A P +GHR R + + G R Sbjct: 155 ----SQRQGHRVS---------SRATESAPGPQSQFQGHRVSARATESVPGPQSQRQGHR 201 Query: 228 RGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTE 262 SR++ S ++Q + +A + G +++ Sbjct: 202 VSSRATESVPGPQSQFQGHRVSARATESVPGPQSQ 236 Score = 46.6 bits (109), Expect = 2e-05 Identities = 45/187 (24%), Positives = 67/187 (35%), Gaps = 20/187 (10%) Query: 98 SGHRTEKRKPQQPQCRPAGGTGQRRGSGSS----PSADQQGAQDREEEAAAAPAPTSR-- 151 S H + + +PQ + QR + P + QG + + P P S+ Sbjct: 19 SCHHSWHPQTPKPQIKAHDSLHQRSARATESVPGPQSQCQGHRVSSRATESVPGPQSQFQ 78 Query: 152 GHRTEKRKPQQPQRRPAAGTGQRRGSRSS-----PSADQQG--AQDREEEAAAAPVPTSR 204 GHR R + + G R SR++ P + +QG R E+A P + Sbjct: 79 GHRVSARATESVPGPQSQCQGHRVSSRATESVPGPQSQRQGHRVSARATESAPGPQSQCQ 138 Query: 205 GHRTEKRKRQQ---PQCRPAAGTGQRRGSRSSPSADQQ----RAQDREEEAAAAPAPTSS 257 GHR R + PQ + R + S+P Q R R E+ P Sbjct: 139 GHRVSARATESVPGPQSQRQGHRVSSRATESAPGPQSQFQGHRVSARATESVPGPQSQRQ 198 Query: 258 GHRTEKR 264 GHR R Sbjct: 199 GHRVSSR 205 Score = 41.6 bits (96), Expect = 7e-04 Identities = 35/135 (25%), Positives = 50/135 (37%), Gaps = 11/135 (8%) Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQ----RAQDREEEAA 90 P Q QCQ + + S P + +QG + +AP Q R R E+ Sbjct: 91 PGPQSQCQGHRVSSRATESVPGPQSQRQGHRVSARATESAPGPQSQCQGHRVSARATESV 150 Query: 91 AAPAPTSSGHRTEKRKPQQ---PQCRPAGGTGQRRGSGS--SPSADQQGAQDREEEAAAA 145 P GHR R + PQ + G R + S P + +QG + + Sbjct: 151 PGPQSQRQGHRVSSRATESAPGPQSQFQGHRVSARATESVPGPQSQRQGHRVSSRATESV 210 Query: 146 PAPTS--RGHRTEKR 158 P P S +GHR R Sbjct: 211 PGPQSQFQGHRVSAR 225 Score = 35.0 bits (79), Expect = 0.068 Identities = 32/124 (25%), Positives = 45/124 (36%), Gaps = 11/124 (8%) Query: 39 PQCQPAGGTGQRRGSGSSPSADQQ----GAQDREEEAAAAPAADQQ--RAQDREEEAAAA 92 PQ Q G R + S+P Q R E+ P + +Q R R E+A Sbjct: 113 PQSQRQGHRVSARATESAPGPQSQCQGHRVSARATESVPGPQSQRQGHRVSSRATESAPG 172 Query: 93 PAPTSSGHRTEKRKPQQ---PQCRPAGGTGQRRGSGS--SPSADQQGAQDREEEAAAAPA 147 P GHR R + PQ + G R + S P + QG + + P Sbjct: 173 PQSQFQGHRVSARATESVPGPQSQRQGHRVSSRATESVPGPQSQFQGHRVSARATESVPG 232 Query: 148 PTSR 151 P S+ Sbjct: 233 PQSQ 236 Score = 34.7 bits (78), Expect = 0.088 Identities = 29/106 (27%), Positives = 39/106 (36%), Gaps = 7/106 (6%) Query: 35 PQQQPQCQPAGGTGQRRGSGSSPSADQQG--AQDREEEAAAAPAADQQ--RAQDREEEAA 90 P Q QCQ + + S P + +QG R E+A P + Q R R E+ Sbjct: 131 PGPQSQCQGHRVSARATESVPGPQSQRQGHRVSSRATESAPGPQSQFQGHRVSARATESV 190 Query: 91 AAPAPTSSGHRTEKRKPQQ---PQCRPAGGTGQRRGSGSSPSADQQ 133 P GHR R + PQ + G R + S P Q Sbjct: 191 PGPQSQRQGHRVSSRATESVPGPQSQFQGHRVSARATESVPGPQSQ 236 >gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] Length = 953 Score = 50.1 bits (118), Expect = 2e-06 Identities = 58/261 (22%), Positives = 99/261 (37%), Gaps = 24/261 (9%) Query: 13 RKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAA 72 +KL S + KT + + + GSGSS S + + + Sbjct: 527 KKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRS 586 Query: 73 AAPAA-DQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSAD 131 + ++ R++ R ++ +P+PT S HR R +P P G G++ +P Sbjct: 587 SRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEP-APPPGKAGEKSVKKPAPPPA 645 Query: 132 QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ-----PQRRPAAGTGQRRGSRSSPSADQQ 186 A + A P PT G E R+ ++ P+RR +G+G GS S S+ + Sbjct: 646 PPQA---TKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRS 702 Query: 187 G--AQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDR 244 + ++A +S H + P + R SP+ AQ R Sbjct: 703 RSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSR-----SPAP----AQTR 753 Query: 245 EEEAAAAPAPTSSGHRTEKRK 265 +E+ + G + EKRK Sbjct: 754 KEK---GKSKKEDGVKEEKRK 771 Score = 48.5 bits (114), Expect = 6e-06 Identities = 52/268 (19%), Positives = 107/268 (39%), Gaps = 16/268 (5%) Query: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQG 63 RQ+E++ + RE + E E+ ++Q + + +R D+ Sbjct: 413 RQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDR 472 Query: 64 AQDREEEAAA----APAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTG 119 ++RE+E +P ++A+ ++EAA ++G + ++ + R + Sbjct: 473 EKEREKEKGKPKPRSPQPPSRQAEPPKKEAA------TTGPQVKRADEWKDPWRRSKSPK 526 Query: 120 QRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRS 179 ++ G SPS ++ + A+A+ + S + + R + + SRS Sbjct: 527 KKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRS 586 Query: 180 SPSADQQGAQDREE--EAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSAD 237 S + G++ R ++ +P PT HR R + +P P G++ + +P Sbjct: 587 SRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEP-APPPGKAGEKSVKKPAPPPA 645 Query: 238 QQRAQDREEEAAAAPAPTSSGHRTEKRK 265 +A + A P PT G E R+ Sbjct: 646 PPQA---TKTTAPVPEPTKPGDPREARR 670 Score = 32.0 bits (71), Expect = 0.57 Identities = 31/140 (22%), Positives = 59/140 (42%), Gaps = 14/140 (10%) Query: 57 PSADQQGAQDREEEAAAAPAADQQRAQDREEEA-AAAPAPTSSGHRTEKRKPQQPQCRPA 115 PS +++ EE+ A+ P ++QD++ E + PTSS E + ++ + Sbjct: 58 PSQEEEDNHSDEEDRASEP-----KSQDQDSEVNELSRGPTSSPCEEEGDEGEEDR---- 108 Query: 116 GGTGQRRGSGSSPSAD-QQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQR 174 T R SS + + + D +EE PAP + EK + + + GT + Sbjct: 109 --TSDLRDEASSVTRELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEK-GEGTPRE 165 Query: 175 RGSRSSPSADQQGAQDREEE 194 G S ++ + + +E Sbjct: 166 EGKAGVQSVGEKESLEAAKE 185 Score = 30.8 bits (68), Expect = 1.3 Identities = 29/130 (22%), Positives = 51/130 (39%), Gaps = 9/130 (6%) Query: 18 SSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQ--QGAQDR----EEEA 71 S E + +E+ + P+ Q Q RG SSP ++ +G +DR +EA Sbjct: 59 SQEEEDNHSDEEDRASEPKSQDQDSEVNELS--RGPTSSPCEEEGDEGEEDRTSDLRDEA 116 Query: 72 AAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSAD 131 ++ + D +EE PAP EK + + GT + G S Sbjct: 117 SSVTRELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDE-EKGEGTPREEGKAGVQSVG 175 Query: 132 QQGAQDREEE 141 ++ + + +E Sbjct: 176 EKESLEAAKE 185 Score = 28.5 bits (62), Expect = 6.3 Identities = 30/154 (19%), Positives = 59/154 (38%), Gaps = 18/154 (11%) Query: 120 QRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRS 179 +R +++ +DRE E R H E+ K +Q ++ +R + Sbjct: 407 ERERENRQRERERERERDRERERRQREREREREH--ERDKERQRRKEEWERERAKRDEKD 464 Query: 180 SPSADQQGAQDREEEAA----AAPVPTSR------------GHRTEKRKRQQPQCRPAAG 223 D+ ++RE+E +P P SR G + ++ + R + Sbjct: 465 RQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKS 524 Query: 224 TGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSS 257 ++ G SPS ++R + A+A+ + SS Sbjct: 525 PKKKLGVSVSPSRARRRRKTSASSASASNSSRSS 558 >gi|50962882 G patch domain containing 8 [Homo sapiens] Length = 1502 Score = 49.7 bits (117), Expect = 3e-06 Identities = 50/242 (20%), Positives = 97/242 (40%), Gaps = 18/242 (7%) Query: 16 RESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAP 75 ++ G E E T P ++ + + +++ S ++ D EE+++ A Sbjct: 644 KQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAE 703 Query: 76 AADQ---QRAQDREEEAAAAPAPTSSGHRTEKRKPQQP----QCRPAGGTGQRRGSGSSP 128 + ++ ++ + R++ ++APA + G + E P + R A QRR S P Sbjct: 704 SGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRR---SLP 760 Query: 129 SADQQGAQDREEEAAAAPAPTSRGHRTEKRK--PQQPQRRPAAGTGQRRGSRSSPSADQQ 186 + ++G+ +++E + G R K + P QRR R RS PS+ + Sbjct: 761 A--EEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDE 818 Query: 187 GAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQR----RGSRSSPSADQQRAQ 242 + D P+ E+ R + +G+R R SR S S+ + Sbjct: 819 DSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASS 878 Query: 243 DR 244 D+ Sbjct: 879 DQ 880 Score = 32.7 bits (73), Expect = 0.34 Identities = 36/164 (21%), Positives = 68/164 (41%), Gaps = 30/164 (18%) Query: 113 RPAGGTGQRRGSGSSPSA----DQQGAQDREEEAAAAPAPTSR-----GHRTEKRKPQQP 163 R +GG SGS+ S + G+ E E P+ + HR +K+K + Sbjct: 624 RSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKK 683 Query: 164 ----QRRPAAGTGQRRG-SRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQC 218 +R+ A T ++ + S + ++ + R++ ++AP + RG + E Sbjct: 684 SSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEP-------- 735 Query: 219 RPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTE 262 P +G+ +P ++RAQD + + SSG + E Sbjct: 736 -PGSGS-------PAPPRRRRRAQDDSQRRSLPAEEGSSGKKDE 771 >gi|60097902 filaggrin [Homo sapiens] Length = 4061 Score = 49.3 bits (116), Expect = 3e-06 Identities = 55/265 (20%), Positives = 94/265 (35%), Gaps = 13/265 (4%) Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62 PR ++D S + +T Q G+R GSG SAD Sbjct: 336 PRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSS 395 Query: 63 GAQDREEEAAAAPAADQ-------QRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPA 115 A++ +D+ +A D E + + + SGH + Q Q Sbjct: 396 RHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTR 455 Query: 116 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHR--TEKRKPQQPQRRPAAGTGQ 173 G +G+R SG S S+ Q + + ++A TS G R + + + R A+ GQ Sbjct: 456 GRSGER--SGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQ 513 Query: 174 R--RGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSR 231 RG S +QG+ + + + H T + + + + + R+ Sbjct: 514 DTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRN 573 Query: 232 SSPSADQQRAQDREEEAAAAPAPTS 256 S D R A++ A +S Sbjct: 574 EEQSGDGTRHSGSRHHEASSQADSS 598 Score = 47.8 bits (112), Expect = 1e-05 Identities = 59/238 (24%), Positives = 89/238 (37%), Gaps = 38/238 (15%) Query: 43 PAGGTGQRRGSGSSPSADQQG----------AQDREEEAAAAPAADQQRAQDREEEAAAA 92 P R+GS S D+ G +Q R + + + Q R +E + Sbjct: 3438 PGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGD 3497 Query: 93 PAPTSSGHRTE-------KRKPQQPQCRPAGG-TGQRRGSGSSPSADQQG-AQDREEEAA 143 + S H E R Q Q + AG T + +GS S +D QG ++D E + Sbjct: 3498 GSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSG 3557 Query: 144 AAPAPTSRGHR-TEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPT 202 +A SR HR + + + + R P + R G S + +Q E ++ + Sbjct: 3558 SA----SRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAAS 3613 Query: 203 SRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHR 260 S Q R +A G+R GS SAD R A+ A SGHR Sbjct: 3614 S-----------HEQARSSA--GERHGSHHQQSADSSR-HSGIGHGQASSAVRDSGHR 3657 Score = 47.4 bits (111), Expect = 1e-05 Identities = 59/264 (22%), Positives = 96/264 (36%), Gaps = 35/264 (13%) Query: 15 LRESSEGDQWLENEKTKPLRPQQQP-QCQPAGGTGQRRGSGSSPSADQQG---------- 63 +R+ S +Q +N + + Q + P R+GS S D+ G Sbjct: 816 VRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTT 875 Query: 64 AQDREEEAAAAPAADQQRAQDREEEAAAAPAPTS-------SGHRTEKRKPQQPQCRPAG 116 +Q R + + + R EE + + S S H R Q Q + G Sbjct: 876 SQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEG 935 Query: 117 G-TGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRR 175 T +R+GS S +D +G + E + + + RG E+ + R P + R Sbjct: 936 SRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSR--HGSRHPRSHHEDRA 993 Query: 176 GSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPS 235 G S + +Q E ++ +S ++ R P G+R GSR S Sbjct: 994 GHGHSADSSRQSGTPHAETSSGGQAASSH-----EQARSSP--------GERHGSRHQQS 1040 Query: 236 ADQQRAQDREEEAAAAPAPTSSGH 259 AD R A++ A SGH Sbjct: 1041 ADSSRHSGIPRRQASS-AVRDSGH 1063 Score = 47.4 bits (111), Expect = 1e-05 Identities = 56/250 (22%), Positives = 92/250 (36%), Gaps = 38/250 (15%) Query: 43 PAGGTGQRRGSGSSPSADQQG----------AQDREEEAAAAPAADQQRAQDREEEAAAA 92 P G R+GS S D+ G Q R + + Q R EE + Sbjct: 1493 PGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGD 1552 Query: 93 PAPTSSGHRTE-------KRKPQQPQCRPAGG-TGQRRGSGSSPSADQQGAQDREEEAAA 144 + S E R Q Q AG T +R+GS S D +G + E + Sbjct: 1553 GSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSE 1612 Query: 145 APAPTSRGHRTEK-----RKPQQPQRRPA-----AGTGQRRGSRSSPSADQQGAQDREEE 194 + + G E+ R P+ Q A A + ++ G+R + ++ A +E+ Sbjct: 1613 SASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQ 1672 Query: 195 AAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRR-----GSRSSPSADQQRAQDREEEAA 249 A ++P G R R +Q +GTG+R+ G + + +A D E + Sbjct: 1673 ARSSP-----GERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSE 1727 Query: 250 AAPAPTSSGH 259 + + S H Sbjct: 1728 ESDTQSVSAH 1737 Score = 46.6 bits (109), Expect = 2e-05 Identities = 39/207 (18%), Positives = 78/207 (37%), Gaps = 8/207 (3%) Query: 55 SSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRP 114 S+ S+ Q G + E + A+ Q++A+ E + S+ T+ ++ Sbjct: 1646 SAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSV 1705 Query: 115 AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQR 174 G +G R GS S ++D +G + + + + + H QQ + G Sbjct: 1706 VGDSGNR-GSSGSQASDSEGHSEESDTQSVSAHGQAGPH-------QQSHQESTRGQSGE 1757 Query: 175 RGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSP 234 R RS Q ++ E A P++ G + + ++ + R +A + R P Sbjct: 1758 RSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHP 1817 Query: 235 SADQQRAQDREEEAAAAPAPTSSGHRT 261 + + Q E + + S H + Sbjct: 1818 GSSRGGRQGSHYEQSVDSSGHSGSHHS 1844 Score = 46.2 bits (108), Expect = 3e-05 Identities = 54/223 (24%), Positives = 78/223 (34%), Gaps = 32/223 (14%) Query: 47 TGQRRGSGSSPSADQQ---GAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTE 103 TG R+GS + D +QD ++ P + ++ Q E + + S H + Sbjct: 814 TGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSH 873 Query: 104 KRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQP 163 G + RG S SA + R EE + + S E Sbjct: 874 TTSQ--------GRSDASRGQSGSRSASRT---TRNEEQSRDGSRHSGSRHHEASSHADI 922 Query: 164 QRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAG 223 R AG GQ GSR+S +QD + E GH + + R G Sbjct: 923 SRHSQAGQGQSEGSRTSRRQGSSVSQDSDSE----------GHSEDSERWSGSASRNHRG 972 Query: 224 TGQ---RRGSRSSPSADQQRA-----QDREEEAAAAPAPTSSG 258 + Q R GSR S + RA D ++ A TSSG Sbjct: 973 SAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSG 1015 Score = 46.2 bits (108), Expect = 3e-05 Identities = 54/275 (19%), Positives = 96/275 (34%), Gaps = 28/275 (10%) Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62 PR + TR + +S +G + + ++ P + GQ +GS S +Q Sbjct: 1537 PRSASRQTRNEE--QSGDGSR---HSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSR-RQ 1590 Query: 63 GAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEK-RKPQQPQCRPAGGTGQR 121 G+ ++ + + D +R + A S H + R Q+ + Sbjct: 1591 GSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESS 1650 Query: 122 RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQR------- 174 R SG+ + G Q + A +P G R R Q +GTG+R Sbjct: 1651 RQSGTRHAETSSGGQAASSQEQARSSP---GERHGSRHQQSADSSTDSGTGRRQDSSVVG 1707 Query: 175 ----RGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGS 230 RGS S ++D +G + + + + + H QQ G R Sbjct: 1708 DSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPH-------QQSHQESTRGQSGERSG 1760 Query: 231 RSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKRK 265 RS Q ++ E A P++ G + + + Sbjct: 1761 RSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHE 1795 Score = 43.5 bits (101), Expect = 2e-04 Identities = 51/245 (20%), Positives = 83/245 (33%), Gaps = 38/245 (15%) Query: 36 QQQPQCQPAGGTGQRRGSGSSPSADQ-------------QGAQDREEEAAAAPAADQQRA 82 Q + P G R+GS S D+ QG D + + +A +Q Sbjct: 1162 QDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTR 1221 Query: 83 QDREEEAAAAPAPTSSGHR-------TEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGA 135 +D++ + SG R + + Q + G+ R GSS S D Sbjct: 1222 KDKQ----SGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSE 1277 Query: 136 QDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEA 195 + ++ + + + H + + + + R P R S + +Q E Sbjct: 1278 RHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTE-- 1335 Query: 196 AAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPT 255 S H +Q + P G+R GSR SAD R A++ A Sbjct: 1336 -------SSSHGQAVSSHEQARSSP----GERHGSRHQQSADSSRHSGIGHRQASS-AVR 1383 Query: 256 SSGHR 260 SGHR Sbjct: 1384 DSGHR 1388 Score = 43.1 bits (100), Expect = 2e-04 Identities = 55/273 (20%), Positives = 101/273 (36%), Gaps = 29/273 (10%) Query: 7 EQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQ--RRGSGSSPSADQQGA 64 + +++ + R + L+ +T+ R + Q + + G + R SGS+ A Sbjct: 266 KSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSA 325 Query: 65 QDREEEAAAAPAA-DQQRAQ-----DREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGT 118 ++ + + P + D+ RA D ++ A TSS +T Q Sbjct: 326 WEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQA-----RSSP 380 Query: 119 GQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSR 178 G+R GSG SAD A+ A + RGHR Q + G + ++ Sbjct: 381 GERHGSGHQQSAD-SSRHSATGRGQASSAVSDRGHRGSSGS----QASDSEGHSENSDTQ 435 Query: 179 SSPSADQQGAQDREEEAAAAPVPTSRGHRT-----EKRKRQQPQC---RPAAGTGQRRGS 230 S + G + + + + R R+ + +QP R TG R+GS Sbjct: 436 SVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGS 495 Query: 231 RSSPSADQQR---AQDREEEAAAAPAPTSSGHR 260 + D R +Q+ ++ P + G + Sbjct: 496 HHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQ 528 Score = 43.1 bits (100), Expect = 2e-04 Identities = 50/218 (22%), Positives = 81/218 (37%), Gaps = 18/218 (8%) Query: 47 TGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHR----- 101 +G R SGS + + ++D + ++ +A Q +E A +S R Sbjct: 1385 SGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQ 1444 Query: 102 -TEKRKPQQPQCRPAGGTGQRRGS---GSSPSADQQGAQDREEEAAAAPAPTSRGHRTEK 157 + + + + A TG R+GS + S+ +QD ++ P +SRG R Sbjct: 1445 VSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPG-SSRGGRQGS 1503 Query: 158 RKPQQPQRRPAAG------TGQRRGSRSSPSADQQGA--QDREEEAAAAPVPTSRGHRTE 209 Q R +G T Q R S + + A Q R EE + S E Sbjct: 1504 YHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHE 1563 Query: 210 KRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEE 247 R G G+ GS++S +QDR+ E Sbjct: 1564 PSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSE 1601 Score = 42.7 bits (99), Expect = 3e-04 Identities = 60/305 (19%), Positives = 99/305 (32%), Gaps = 50/305 (16%) Query: 3 PRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ 62 PR ++D S + +T Q Q G+R GS SAD Sbjct: 1633 PRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSS 1692 Query: 63 ---GAQDREEEAAAAPAADQ----QRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPA 115 G R++ + + ++ +A D E + + + S H Q Q Sbjct: 1693 TDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTR 1752 Query: 116 GGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR--------- 166 G +G+R G S Q ++ E A P++ G + + + + R Sbjct: 1753 GQSGERSGRSGS-FLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQD 1811 Query: 167 -----PAAGTGQRRGSRSSPSADQQG----------AQDREE--EAAAAPVPTSRGHRTE 209 P + G R+GS S D G +Q+R + + SR R E Sbjct: 1812 TIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNE 1871 Query: 210 KRK----------------RQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPA 253 K+ R G GQ G R+S + +QD + + + + Sbjct: 1872 KQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDS 1931 Query: 254 PTSSG 258 SG Sbjct: 1932 ERWSG 1936 Score = 42.7 bits (99), Expect = 3e-04 Identities = 48/226 (21%), Positives = 82/226 (36%), Gaps = 19/226 (8%) Query: 51 RGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHR-------TE 103 RG S ++D +G + + + + Q +E+A + SSG + Sbjct: 2037 RGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVST 2096 Query: 104 KRKPQQPQCRPAGGTGQRRGSGSSPSADQQ---GAQDREEEAAAAPAPTSRGHRTEKRKP 160 + + + A TG R+GS + D +Q+ ++ P P SRG R + Sbjct: 2097 HEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGP-SRGGRQGSHQE 2155 Query: 161 QQPQRRPAAGTGQRRGS---RSSPSADQQGAQDR-----EEEAAAAPVPTSRGHRTEKRK 212 Q R +G+ + RS S Q G++ ++E + S H E Sbjct: 2156 QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASS 2215 Query: 213 RQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSG 258 G GQ G R+S +QD + E + + SG Sbjct: 2216 WADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSG 2261 Score = 40.8 bits (94), Expect = 0.001 Identities = 44/232 (18%), Positives = 82/232 (35%), Gaps = 19/232 (8%) Query: 52 GSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHR-------TEK 104 GS S ++D +G + + + + Q +E+A + SG + Sbjct: 3334 GSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTH 3393 Query: 105 RKPQQPQCRPAGGTGQRRGSGSSPSADQQ---GAQDREEEAAAAPAPTSRGHRTEKRKPQ 161 + + R TG+R+GS + D +Q+ ++ P + RG R Q Sbjct: 3394 EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRG-RQGSHYEQ 3452 Query: 162 QPQRRPAAGT--------GQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKR 213 R +G+ G+ SR + Q R +E + S H E + Sbjct: 3453 SVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQ 3512 Query: 214 QQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKRK 265 +G GQ G R+S + +QD + + + + SG + + Sbjct: 3513 ADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHR 3564 Score = 40.0 bits (92), Expect = 0.002 Identities = 52/234 (22%), Positives = 82/234 (35%), Gaps = 21/234 (8%) Query: 51 RGSGSSPSADQQGAQDREE--------EAAAAPAADQQRAQDREEEAAAAPAPTSSGHRT 102 RGS S + D +G + + +A + Q+ A+DR E + T Sbjct: 740 RGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVST 799 Query: 103 EKRKPQQPQCRPAGGTGQRRGSGSSPSADQQ---GAQDREEEAAAAPAPTSRGHRTEKRK 159 K+ + TG R+GS + D +QD ++ P + RG R Sbjct: 800 HKQS-ESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRG-RQGSHH 857 Query: 160 PQQPQRRPAAGTGQRRGS---RSSPSADQQGAQD-----REEEAAAAPVPTSRGHRTEKR 211 Q R +G+ + RS S Q G++ R EE + S E Sbjct: 858 EQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEAS 917 Query: 212 KRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTEKRK 265 AG GQ GSR+S +QD + E + + SG + + Sbjct: 918 SHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHR 971 Score = 40.0 bits (92), Expect = 0.002 Identities = 52/218 (23%), Positives = 78/218 (35%), Gaps = 37/218 (16%) Query: 43 PAGGTGQRRGSGSSPSADQQG----------AQDREEEAAAAPAADQQRAQDREEEAAAA 92 P G R+G S D G +Q R + + + R EE + Sbjct: 3114 PGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGD 3173 Query: 93 PAPTS-------SGHRTEKRKPQQPQCRPAGGTGQRR-GSGSSPSADQQG-AQDREEEAA 143 + S S H R Q Q + G RR GS S +D +G ++D E + Sbjct: 3174 SSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSG 3233 Query: 144 AAPAPTSRGHR-TEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPT 202 +A SR HR + + + + R P + R G S +Q E ++ + Sbjct: 3234 SA----SRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAAS 3289 Query: 203 SRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQR 240 S ++ R P G+R GSR SAD R Sbjct: 3290 SH-----EQARSSP--------GERHGSRHQQSADSSR 3314 Score = 39.7 bits (91), Expect = 0.003 Identities = 51/232 (21%), Positives = 84/232 (36%), Gaps = 20/232 (8%) Query: 47 TGQRRGSGSSPSADQQGAQDREEEAAAA--PAADQQRAQDREEEAAAAPAPTSSG----H 100 +G R SGS S + ++D + ++ +A A Q++ +A SG Sbjct: 3654 SGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQ 3713 Query: 101 RTEKRKPQQPQCRPAGGTGQRRGSGSSPSAD--QQGAQDREEEAAAAPAPTSRGHRTEKR 158 + + + R TG R+GS + D + A ++ + RG R Sbjct: 3714 VSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSY 3773 Query: 159 KPQQPQRRPAAG------TGQRRGSRS-SPSADQQGAQDREEEAAAAPVPTSRGHRTEKR 211 Q R +G T Q R S S + +++ E + G R + Sbjct: 3774 HEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEA 3833 Query: 212 KRQQPQCRPA-AGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHRTE 262 Q R + +G G+ GSR S +QD + EA P S R+E Sbjct: 3834 STQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEA----YPEDSERRSE 3881 Score = 39.3 bits (90), Expect = 0.004 Identities = 49/235 (20%), Positives = 80/235 (34%), Gaps = 31/235 (13%) Query: 43 PAGGTGQRRGSGSSPSADQQG----------AQDREEEAAAAPAADQQRAQDREEEAAAA 92 P G R+GS S ++ G +Q R + + + Q R EE + Sbjct: 520 PGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSG- 578 Query: 93 PAPTSSGHRTEKRKPQQPQCRPAG-GTGQRRG------SGSSPSADQQGAQDREEEAAAA 145 SG R + Q R + G GQ G GSS S D E+ + Sbjct: 579 DGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWS 638 Query: 146 PAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRG 205 + + H + + + + R P + R G S + ++ + +++ +S Sbjct: 639 GSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSH- 697 Query: 206 HRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHR 260 Q R +AG +R GSR + A+ A SGHR Sbjct: 698 ----------EQARSSAG--ERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHR 740 Score = 38.9 bits (89), Expect = 0.005 Identities = 49/217 (22%), Positives = 74/217 (34%), Gaps = 25/217 (11%) Query: 47 TGQRRGSGSSPSADQQ---GAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTE 103 TG R+GS + D +Q+ ++ P + + Q E + SGH Sbjct: 489 TGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSV----NRSGHSGS 544 Query: 104 KRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQP 163 Q R GQ SGS ++ Q R EE + S E Sbjct: 545 HHSHTTSQGRSDASHGQ---SGSRSAS----RQTRNEEQSGDGTRHSGSRHHEASSQADS 597 Query: 164 QRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAG 223 R G GQ G R+S + +QD + S+GH + + R G Sbjct: 598 SRHSQVGQGQSSGPRTSRNQGSSVSQDSD----------SQGHSEDSERWSGSASRNHHG 647 Query: 224 TGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHR 260 + Q + SR + +DR +A + SG R Sbjct: 648 SAQEQ-SRDGSRHPRSHHEDRAGHGHSADSSRKSGTR 683 Score = 38.9 bits (89), Expect = 0.005 Identities = 52/256 (20%), Positives = 86/256 (33%), Gaps = 23/256 (8%) Query: 7 EQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQ---G 63 ++ TR R S +L T + P+ TG R+GS + D Sbjct: 3693 QESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPS--TGGRQGSRHEQARDSSRHSA 3750 Query: 64 AQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRG 123 +Q+ ++ P + + Q E + + S H + G + G Sbjct: 3751 SQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQ--------GRSDASHG 3802 Query: 124 SGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSA 183 S SA ++ R EE + + S E R +G G+ GSR S Sbjct: 3803 QSGSRSASRE---TRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQ 3859 Query: 184 DQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQD 243 +QD + EA P R+E R ++ R GSR S+ + A Sbjct: 3860 GSSVSQDSDSEA----YPEDSERRSESASRNH---HGSSREQSRDGSRHPGSSHRDTASH 3912 Query: 244 REEEAAAAPAPTSSGH 259 + + + T+ H Sbjct: 3913 VQSSPVQSDSSTAKEH 3928 Score = 38.1 bits (87), Expect = 0.008 Identities = 46/213 (21%), Positives = 73/213 (34%), Gaps = 36/213 (16%) Query: 47 TGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRK 106 +G R SGS S ++ ++D + ++ +A Q +E A T SGH Sbjct: 2682 SGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGET-SGH------ 2734 Query: 107 PQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR 166 S Q ++ E + P++RG + + + Q R Sbjct: 2735 -------------------SGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR 2775 Query: 167 PAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQ 226 +A + R P + + G Q E + S GH Q R A GQ Sbjct: 2776 HSASQDGQDTIRGHPGSSRGGRQGYHHEHSV----DSSGHSGSHHSHTTSQGRSDASRGQ 2831 Query: 227 RRGSRSSPSADQQRAQDREEEAAAAPAPTSSGH 259 GSRS+ R EE++ + S H Sbjct: 2832 -SGSRSA-----SRTTRNEEQSGDGSRHSGSRH 2858 Score = 37.0 bits (84), Expect = 0.018 Identities = 46/213 (21%), Positives = 74/213 (34%), Gaps = 36/213 (16%) Query: 47 TGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRK 106 +G R SGS S ++ ++D + ++ +A Q +E A T SGH Sbjct: 3006 SGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGET-SGH------ 3058 Query: 107 PQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR 166 S Q ++ E + P++RG + + + Q R Sbjct: 3059 -------------------SGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR 3099 Query: 167 PAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQ 226 +A + R P + + G Q E + S GH Q R A GQ Sbjct: 3100 HSASQYGQDTIRGHPGSSRGGRQGYHHEHSV----DSSGHSGSHHSHTTSQGRSDASRGQ 3155 Query: 227 RRGSRSSPSADQQRAQDREEEAAAAPAPTSSGH 259 GSRS+ R EE++ + + S H Sbjct: 3156 -SGSRSA-----SRTTRNEEQSGDSSRHSVSRH 3182 Score = 36.2 bits (82), Expect = 0.030 Identities = 41/179 (22%), Positives = 64/179 (35%), Gaps = 23/179 (12%) Query: 83 QDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQG-AQDREEE 141 + R + ++ S H + P Q T +RRGS S D +G ++D E Sbjct: 259 RSRSSDGKSSSQVNRSRHENTSQVPLQES-----RTRKRRGSRVSQDRDSEGHSEDSERH 313 Query: 142 AAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVP 201 + +A SR H +A R GSR S D+ A ++ Sbjct: 314 SGSA----SRNHHG------------SAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSG 357 Query: 202 TSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSGHR 260 T + + + + + G+R GS SAD R A+ A + GHR Sbjct: 358 TRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSR-HSATGRGQASSAVSDRGHR 415 Score = 36.2 bits (82), Expect = 0.030 Identities = 50/229 (21%), Positives = 81/229 (35%), Gaps = 18/229 (7%) Query: 47 TGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTS--SG----H 100 +G R SGS S + ++D + ++ +A Q +E A S SG Sbjct: 2358 SGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQ 2417 Query: 101 RTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQG---AQDREEEAAAAPAPTSRGHRTEK 157 + + + R TG R+GS + D +Q+ ++ P +S G R Sbjct: 2418 VSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGG-RQGS 2476 Query: 158 RKPQQPQRRPAAG------TGQRRGSRSSPSADQQGA--QDREEEAAAAPVPTSRGHRTE 209 Q R +G T Q R S + + A Q R +E + S E Sbjct: 2477 HYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHE 2536 Query: 210 KRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSSG 258 R G GQ G R+S + +QD + + + + SG Sbjct: 2537 ASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSG 2585 Score = 32.7 bits (73), Expect = 0.34 Identities = 57/238 (23%), Positives = 80/238 (33%), Gaps = 52/238 (21%) Query: 48 GQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKP 107 GQ GS S +QD + E ++D E + +A S HR ++ Sbjct: 3200 GQSEGSRRSRRQGSSVSQDSDSEG---------HSEDSERWSGSA----SRNHRGSVQEQ 3246 Query: 108 QQPQCR-PAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRR 166 + R P R G G S +Q E ++ A +S H + P Sbjct: 3247 SRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASS--HEQARSSP------ 3298 Query: 167 PAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSR-------------GHRTEKRKR 213 G+R GSR SAD A++ V SR GH +E+ Sbjct: 3299 -----GERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGH-SEESDT 3352 Query: 214 QQPQCRPAAGTGQ---------RRGSRSSPSAD--QQRAQDREEEAAAAPAPTSSGHR 260 Q AG Q R G RS S Q + + E+A TS+G R Sbjct: 3353 QSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRR 3410 >gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo sapiens] Length = 384 Score = 49.3 bits (116), Expect = 3e-06 Identities = 66/229 (28%), Positives = 85/229 (37%), Gaps = 39/229 (17%) Query: 27 NEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDRE 86 + +T+P P+ + G R GSG++ SA + + PAA R Sbjct: 76 DSRTRPAARPPHPRTRSPPG---RSGSGTTFSAVPPRPSQHQSGSRLRPAAPGPRPGCSS 132 Query: 87 EEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ-RRGSGSSPSADQQGAQDREEEAAAA 145 A+ APA + RT P +GG+G RG GS DQ GA R A Sbjct: 133 ARASPAPAAPQAAART------APGRAASGGSGPGSRGQGS----DQVGA--RPSRAGGQ 180 Query: 146 PAP-TSRGHRTEKRKPQQPQR--------RPAAGTGQR------------RGSRSSPSAD 184 P P T R R R+ +P R RP +GTG R + SSPSAD Sbjct: 181 PPPLTCRRCRAAPRRSARPFRRPGLPLKSRPGSGTGARSCGTWGSGGGPGTAAASSPSAD 240 Query: 185 --QQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSR 231 Q A V G R + QP CR + RR R Sbjct: 241 FSSDSPQPIIIFGGALRVRGCGGRRRSNGQGTQPGCRLLSPAPPRRRYR 289 >gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo sapiens] Length = 384 Score = 49.3 bits (116), Expect = 3e-06 Identities = 66/229 (28%), Positives = 85/229 (37%), Gaps = 39/229 (17%) Query: 27 NEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDRE 86 + +T+P P+ + G R GSG++ SA + + PAA R Sbjct: 76 DSRTRPAARPPHPRTRSPPG---RSGSGTTFSAVPPRPSQHQSGSRLRPAAPGPRPGCSS 132 Query: 87 EEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ-RRGSGSSPSADQQGAQDREEEAAAA 145 A+ APA + RT P +GG+G RG GS DQ GA R A Sbjct: 133 ARASPAPAAPQAAART------APGRAASGGSGPGSRGQGS----DQVGA--RPSRAGGQ 180 Query: 146 PAP-TSRGHRTEKRKPQQPQR--------RPAAGTGQR------------RGSRSSPSAD 184 P P T R R R+ +P R RP +GTG R + SSPSAD Sbjct: 181 PPPLTCRRCRAAPRRSARPFRRPGLPLKSRPGSGTGARSCGTWGSGGGPGTAAASSPSAD 240 Query: 185 --QQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSR 231 Q A V G R + QP CR + RR R Sbjct: 241 FSSDSPQPIIIFGGALRVRGCGGRRRSNGQGTQPGCRLLSPAPPRRRYR 289 >gi|239508962 PREDICTED: hypothetical protein [Homo sapiens] Length = 384 Score = 49.3 bits (116), Expect = 3e-06 Identities = 66/229 (28%), Positives = 85/229 (37%), Gaps = 39/229 (17%) Query: 27 NEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDRE 86 + +T+P P+ + G R GSG++ SA + + PAA R Sbjct: 76 DSRTRPAARPPHPRTRSPPG---RSGSGTTFSAVPPRPSQHQSGSRLRPAAPGPRPGCSS 132 Query: 87 EEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQ-RRGSGSSPSADQQGAQDREEEAAAA 145 A+ APA + RT P +GG+G RG GS DQ GA R A Sbjct: 133 ARASPAPAAPQAAART------APGRAASGGSGPGSRGQGS----DQVGA--RPSRAGGQ 180 Query: 146 PAP-TSRGHRTEKRKPQQPQR--------RPAAGTGQR------------RGSRSSPSAD 184 P P T R R R+ +P R RP +GTG R + SSPSAD Sbjct: 181 PPPLTCRRCRAAPRRSARPFRRPGLPLKSRPGSGTGARSCGTWGSGGGPGTAAASSPSAD 240 Query: 185 --QQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSR 231 Q A V G R + QP CR + RR R Sbjct: 241 FSSDSPQPIIIFGGALRVRGCGGRRRSNGQGTQPGCRLLSPAPPRRRYR 289 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 49.3 bits (116), Expect = 3e-06 Identities = 51/208 (24%), Positives = 69/208 (33%), Gaps = 32/208 (15%) Query: 27 NEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDRE 86 ++ P P +PQ P G Q +G P Q ++ P + + Sbjct: 146 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQG---- 201 Query: 87 EEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAP 146 P P R+ + P +PQ P G Q +G P Q P Sbjct: 202 ------PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ------------GP 243 Query: 147 APTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGH 206 P P +PQ PA G G + S SP QG +E P P + G+ Sbjct: 244 PPQGGNKPQGPPPPGKPQGPPAQG-GSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGN 302 Query: 207 RTEKRKRQQPQCRPAAGTGQRRGSRSSP 234 QQPQ PA GQ +G P Sbjct: 303 ------PQQPQAPPA---GQPQGPPRPP 321 Score = 48.1 bits (113), Expect = 8e-06 Identities = 52/236 (22%), Positives = 73/236 (30%), Gaps = 30/236 (12%) Query: 27 NEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDRE 86 ++ P P +PQ P G Q +G P Q P + + Sbjct: 85 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQG---- 140 Query: 87 EEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQ----QGAQDRE--- 139 P P R+ + P +PQ P G Q +G P Q QG + + Sbjct: 141 ------PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPP 194 Query: 140 -EEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAA 198 P P R+ + P +PQ P G Q +G P QG + Sbjct: 195 PPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGP-PPPPGKPQGPPPQGGNKPQG 253 Query: 199 PVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAP 254 P P + PQ PA G + + +RS P Q Q P P Sbjct: 254 PPPPGK-----------PQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPP 298 Score = 38.5 bits (88), Expect = 0.006 Identities = 41/178 (23%), Positives = 57/178 (32%), Gaps = 16/178 (8%) Query: 93 PAPTSSGHRTEKRKPQQPQCRPAGGTGQRRGSGSSPSADQ----QGAQDRE----EEAAA 144 P P R+ + P +PQ P G Q +G P Q QG + Sbjct: 80 PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQ 139 Query: 145 APAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSRSSPSADQ----QGAQDRE----EEAA 196 P P R+ + P +PQ P G Q +G P Q QG + + Sbjct: 140 GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKP 199 Query: 197 AAPVPTSRGHRTEKRKRQQPQCRPAAGTGQRRGSRSSPSADQQRAQDREEEAAAAPAP 254 P P R+ + +PQ P G Q +G P Q + P P Sbjct: 200 QGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 257 >gi|38788260 bromodomain PHD finger transcription factor isoform 2 [Homo sapiens] Length = 2903 Score = 48.9 bits (115), Expect = 5e-06 Identities = 47/179 (26%), Positives = 70/179 (39%), Gaps = 17/179 (9%) Query: 44 AGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTE 103 A GTG++R S SP Q QD+ A + + AQ + + +A P P +T+ Sbjct: 2358 AAGTGEQRQSKLSPQ--MQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQP-----QTQ 2410 Query: 104 KRKPQQP--QCRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQ 161 + P QP Q +P T S A AQ + + AA P S + Q Sbjct: 2411 PQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQ 2470 Query: 162 QPQRRPAAGTGQRRGSRSSPSADQQGAQDREEEAAAAPVPTSRGHRTEKRKRQQPQCRP 220 P Q R S+PS G Q + + + P+P + + QPQ +P Sbjct: 2471 SPS--------QTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQP 2521 Score = 34.7 bits (78), Expect = 0.088 Identities = 35/118 (29%), Positives = 43/118 (36%), Gaps = 25/118 (21%) Query: 62 QGAQDREEEAAAAPAADQQRAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAGGTGQR 121 +G + R + AAPAA E A AP P P P P GG R Sbjct: 2 RGRRGRPPKQPAAPAA---------ERCAPAPPPP----------PPPPTSGPIGGLRSR 42 Query: 122 -RGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAAGTGQRRGSR 178 RGS A Q E A + RG + +RKP P P + + RG R Sbjct: 43 HRGSSRGRWAAAQA-----EVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGGR 95 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.303 0.118 0.332 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,714,230 Number of Sequences: 37866 Number of extensions: 890390 Number of successful extensions: 11496 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 301 Number of HSP's successfully gapped in prelim test: 1332 Number of HSP's that attempted gapping in prelim test: 6510 Number of HSP's gapped (non-prelim): 4467 length of query: 265 length of database: 18,247,518 effective HSP length: 100 effective length of query: 165 effective length of database: 14,460,918 effective search space: 2386051470 effective search space used: 2386051470 T: 11 A: 40 X1: 17 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.9 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.