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Search of human proteins with 239049540
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239049540 FCH domain only 1 isoform c [Homo sapiens]
(839 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239049540 FCH domain only 1 isoform c [Homo sapiens] 1682 0.0
gi|239049457 FCH domain only 1 isoform b [Homo sapiens] 1682 0.0
gi|29789054 FCH domain only 1 isoform b [Homo sapiens] 1682 0.0
gi|239049440 FCH domain only 1 isoform a [Homo sapiens] 1667 0.0
gi|226371723 FCH domain only 2 isoform a [Homo sapiens] 657 0.0
gi|226371725 FCH domain only 2 isoform b [Homo sapiens] 604 e-173
gi|116235472 SH3-domain GRB2-like (endophilin) interacting prote... 312 7e-85
gi|20149528 proline-serine-threonine phosphatase interacting pro... 69 1e-11
gi|165905601 proline-serine-threonine phosphatase interacting pr... 61 4e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 55 2e-07
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 55 3e-07
gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens] 54 6e-07
gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens] 54 6e-07
gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens] 54 6e-07
gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens] 54 6e-07
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 54 6e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni... 54 6e-07
gi|157168329 formin 1 [Homo sapiens] 53 1e-06
gi|239752265 PREDICTED: hypothetical protein XP_002348186 [Homo ... 52 3e-06
gi|51702222 SPT2, Suppressor of Ty, domain containing 1 [Homo sa... 51 5e-06
gi|157743252 pecanex-like 3 [Homo sapiens] 50 7e-06
gi|18959210 WIRE protein [Homo sapiens] 50 7e-06
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s... 50 9e-06
gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa... 50 9e-06
gi|157074225 nuclear pore complex interacting protein-like 3 [Ho... 50 9e-06
gi|150170670 piccolo isoform 2 [Homo sapiens] 50 1e-05
gi|150378539 piccolo isoform 1 [Homo sapiens] 50 1e-05
gi|33356148 formin-like 1 [Homo sapiens] 49 1e-05
gi|223972704 hypothetical protein LOC284418 [Homo sapiens] 49 3e-05
gi|41281612 zinc finger protein 828 [Homo sapiens] 49 3e-05
>gi|239049540 FCH domain only 1 isoform c [Homo sapiens]
Length = 839
Score = 1682 bits (4356), Expect = 0.0
Identities = 839/839 (100%), Positives = 839/839 (100%)
Query: 1 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH 60
MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH
Sbjct: 1 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH 60
Query: 61 KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK 120
KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK
Sbjct: 61 KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK 120
Query: 121 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 180
AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG
Sbjct: 121 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 180
Query: 181 QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR 240
QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR
Sbjct: 181 QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR 240
Query: 241 LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD 300
LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD
Sbjct: 241 LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD 300
Query: 301 DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ 360
DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ
Sbjct: 301 DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ 360
Query: 361 RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE 420
RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE
Sbjct: 361 RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE 420
Query: 421 NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS 480
NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS
Sbjct: 421 NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS 480
Query: 481 PGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG 540
PGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG
Sbjct: 481 PGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG 540
Query: 541 SSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLAR 600
SSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLAR
Sbjct: 541 SSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLAR 600
Query: 601 VTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDF 660
VTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDF
Sbjct: 601 VTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDF 660
Query: 661 WLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSV 720
WLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSV
Sbjct: 661 WLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSV 720
Query: 721 EYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSG 780
EYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSG
Sbjct: 721 EYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSG 780
Query: 781 RLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC 839
RLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC
Sbjct: 781 RLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC 839
>gi|239049457 FCH domain only 1 isoform b [Homo sapiens]
Length = 889
Score = 1682 bits (4356), Expect = 0.0
Identities = 839/839 (100%), Positives = 839/839 (100%)
Query: 1 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH 60
MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH
Sbjct: 51 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH 110
Query: 61 KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK 120
KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK
Sbjct: 111 KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK 170
Query: 121 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 180
AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG
Sbjct: 171 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 230
Query: 181 QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR 240
QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR
Sbjct: 231 QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR 290
Query: 241 LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD 300
LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD
Sbjct: 291 LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD 350
Query: 301 DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ 360
DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ
Sbjct: 351 DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ 410
Query: 361 RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE 420
RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE
Sbjct: 411 RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE 470
Query: 421 NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS 480
NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS
Sbjct: 471 NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS 530
Query: 481 PGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG 540
PGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG
Sbjct: 531 PGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG 590
Query: 541 SSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLAR 600
SSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLAR
Sbjct: 591 SSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLAR 650
Query: 601 VTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDF 660
VTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDF
Sbjct: 651 VTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDF 710
Query: 661 WLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSV 720
WLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSV
Sbjct: 711 WLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSV 770
Query: 721 EYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSG 780
EYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSG
Sbjct: 771 EYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSG 830
Query: 781 RLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC 839
RLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC
Sbjct: 831 RLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC 889
>gi|29789054 FCH domain only 1 isoform b [Homo sapiens]
Length = 889
Score = 1682 bits (4356), Expect = 0.0
Identities = 839/839 (100%), Positives = 839/839 (100%)
Query: 1 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH 60
MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH
Sbjct: 51 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH 110
Query: 61 KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK 120
KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK
Sbjct: 111 KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK 170
Query: 121 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 180
AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG
Sbjct: 171 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 230
Query: 181 QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR 240
QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR
Sbjct: 231 QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR 290
Query: 241 LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD 300
LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD
Sbjct: 291 LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD 350
Query: 301 DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ 360
DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ
Sbjct: 351 DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ 410
Query: 361 RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE 420
RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE
Sbjct: 411 RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE 470
Query: 421 NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS 480
NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS
Sbjct: 471 NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS 530
Query: 481 PGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG 540
PGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG
Sbjct: 531 PGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG 590
Query: 541 SSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLAR 600
SSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLAR
Sbjct: 591 SSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLAR 650
Query: 601 VTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDF 660
VTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDF
Sbjct: 651 VTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDF 710
Query: 661 WLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSV 720
WLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSV
Sbjct: 711 WLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSV 770
Query: 721 EYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSG 780
EYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSG
Sbjct: 771 EYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSG 830
Query: 781 RLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC 839
RLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC
Sbjct: 831 RLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC 889
>gi|239049440 FCH domain only 1 isoform a [Homo sapiens]
Length = 891
Score = 1667 bits (4317), Expect = 0.0
Identities = 832/832 (100%), Positives = 832/832 (100%)
Query: 1 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH 60
MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH
Sbjct: 51 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH 110
Query: 61 KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK 120
KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK
Sbjct: 111 KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK 170
Query: 121 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 180
AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG
Sbjct: 171 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 230
Query: 181 QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR 240
QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR
Sbjct: 231 QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR 290
Query: 241 LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD 300
LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD
Sbjct: 291 LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD 350
Query: 301 DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ 360
DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ
Sbjct: 351 DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ 410
Query: 361 RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE 420
RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE
Sbjct: 411 RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE 470
Query: 421 NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS 480
NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS
Sbjct: 471 NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS 530
Query: 481 PGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG 540
PGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG
Sbjct: 531 PGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG 590
Query: 541 SSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLAR 600
SSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLAR
Sbjct: 591 SSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLAR 650
Query: 601 VTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDF 660
VTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDF
Sbjct: 651 VTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDF 710
Query: 661 WLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSV 720
WLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSV
Sbjct: 711 WLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSV 770
Query: 721 EYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSG 780
EYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSG
Sbjct: 771 EYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSG 830
Query: 781 RLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFAT 832
RLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFAT
Sbjct: 831 RLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFAT 882
>gi|226371723 FCH domain only 2 isoform a [Homo sapiens]
Length = 810
Score = 657 bits (1694), Expect = 0.0
Identities = 367/847 (43%), Positives = 523/847 (61%), Gaps = 97/847 (11%)
Query: 1 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH 60
M KL+K ASN + +GTFAP+W+VF+ S++KLA CHL+L RKLQ+LIK+V +YGEEQ+K+H
Sbjct: 53 MTKLAKSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSH 112
Query: 61 KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK 120
KK KEEV TL+AVQ + ++Q L KS+ENY +C++QERL++E +Q+E++KA K+KK
Sbjct: 113 KKTKEEVAGTLEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKK 172
Query: 121 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 180
A ++ + VEKY A+ADFEQKM ++A +FQ +EETHL H+K ++GS ++++++ H+QIG
Sbjct: 173 ATDTYKLYVEKYALAKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAIKEIHLQIG 232
Query: 181 QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR 240
QVHEEF N+ N +VE L++KFAESKGTG+E+PG ++FE A+ E +K R K F
Sbjct: 233 QVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEGIKP-RKRKTFA 291
Query: 241 LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD 300
LPG+ ++E++ E +V+ + DS P+VDEEG++++P+ QN T E +SSSDSD +
Sbjct: 292 LPGIIKKEKDAE---SVECPDADSLNIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSE 348
Query: 301 DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGG----TMKRHSSRDAA 356
DEEP+K+ + IKP + A+ +L+ + G++ L P M R+ S +
Sbjct: 349 DEEPKKYRIEIKPMHPN-NSHHTMASLDELKVSIGNITLSPAISRHSPVQMNRNLSNEEL 407
Query: 357 GKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSS 416
K +P + P ++ L + LFGP L+S SSS TSS S
Sbjct: 408 TK-SKPSAPPNEKGTSDLLAWDP-----LFGPSLDS---------SSSSSLTSSSS---- 448
Query: 417 SSPENVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQP 476
RP TP S + I PP P S
Sbjct: 449 ---------------------------ARPTTPLSVGT----------IVPPPRPASRPK 471
Query: 477 LASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSP 536
L S L+G + +P P P + PP + PL R+ S
Sbjct: 472 LTSG-------KLSGINEIPRPFSPPVTSNTSPPP--------AAPLARAE-------SS 509
Query: 537 SPLGSSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPS 596
S + SSA+ +A P+ GVSRGPSPV LG+QD LP+A A TE V+AYF+G P+
Sbjct: 510 SSISSSASLSAANTPTV------GVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPT 563
Query: 597 -CLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDP 655
C+ ++TG++TM+FP+GI++VF+ P P VL FR+ + + +E PNA L+FSDPSQ D
Sbjct: 564 KCIVKITGDMTMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDS 623
Query: 656 ETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATL 715
TKDFW+NM A+T L++ +EQNP ASYYNV +L+YQ S G QS PL L+ +W+C A+
Sbjct: 624 NTKDFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSAST 683
Query: 716 TQVSVEYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSE 775
T + V+Y Y P A P+ L+N+Q+++PV VTN++ P A WN E+ + W+L +SE
Sbjct: 684 TDLRVDYKYNPEAMVAPSVLSNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSSISE 743
Query: 776 A---GGSGRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFAT 832
GGSG L A ++ GPS P+ +A QF SEG+TLSGVD ELVG+GYR+SL+K+RFAT
Sbjct: 744 KSENGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFAT 803
Query: 833 GMYLVSC 839
G YL C
Sbjct: 804 GRYLADC 810
>gi|226371725 FCH domain only 2 isoform b [Homo sapiens]
Length = 777
Score = 604 bits (1558), Expect = e-173
Identities = 352/847 (41%), Positives = 496/847 (58%), Gaps = 130/847 (15%)
Query: 1 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH 60
M KL+K ASN + +GTFAP+W+VF+ S++KLA CHL+L RKLQ+LIK+V +YGEEQ+K+H
Sbjct: 53 MTKLAKSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSH 112
Query: 61 KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK 120
KK KEEV TL+AVQ + ++Q L KS+ENY +C++QERL++E +Q+E++KA K+KK
Sbjct: 113 KKTKEEVAGTLEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKK 172
Query: 121 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 180
A ++ + VEKY A+ADFEQKM ++A
Sbjct: 173 ATDTYKLYVEKYALAKADFEQKMTETA--------------------------------- 199
Query: 181 QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR 240
QVHEEF N+ N +VE L++KFAESKGTG+E+PG ++FE A+ E +K R K F
Sbjct: 200 QVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEGIKP-RKRKTFA 258
Query: 241 LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD 300
LPG+ ++E++ E +V+ + DS P+VDEEG++++P+ QN T E +SSSDSD +
Sbjct: 259 LPGIIKKEKDAE---SVECPDADSLNIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSE 315
Query: 301 DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGG----TMKRHSSRDAA 356
DEEP+K+ + IKP + A+ +L+ + G++ L P M R+ S +
Sbjct: 316 DEEPKKYRIEIKPMHPN-NSHHTMASLDELKVSIGNITLSPAISRHSPVQMNRNLSNEEL 374
Query: 357 GKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSS 416
K +P + P ++ L + LFGP L+S SSS TSS S
Sbjct: 375 TK-SKPSAPPNEKGTSDLLAWDP-----LFGPSLDS---------SSSSSLTSSSS---- 415
Query: 417 SSPENVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQP 476
RP TP S + I PP P S
Sbjct: 416 ---------------------------ARPTTPLSVGT----------IVPPPRPASRPK 438
Query: 477 LASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSP 536
L S L+G + +P P P + PP + PL R+ S
Sbjct: 439 LTSG-------KLSGINEIPRPFSPPVTSNTSPPP--------AAPLARAE-------SS 476
Query: 537 SPLGSSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPS 596
S + SSA+ +A P+ GVSRGPSPV LG+QD LP+A A TE V+AYF+G P+
Sbjct: 477 SSISSSASLSAANTPTV------GVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPT 530
Query: 597 -CLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDP 655
C+ ++TG++TM+FP+GI++VF+ P P VL FR+ + + +E PNA L+FSDPSQ D
Sbjct: 531 KCIVKITGDMTMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDS 590
Query: 656 ETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATL 715
TKDFW+NM A+T L++ +EQNP ASYYNV +L+YQ S G QS PL L+ +W+C A+
Sbjct: 591 NTKDFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSAST 650
Query: 716 TQVSVEYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSE 775
T + V+Y Y P A P+ L+N+Q+++PV VTN++ P A WN E+ + W+L +SE
Sbjct: 651 TDLRVDYKYNPEAMVAPSVLSNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSSISE 710
Query: 776 A---GGSGRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFAT 832
GGSG L A ++ GPS P+ +A QF SEG+TLSGVD ELVG+GYR+SL+K+RFAT
Sbjct: 711 KSENGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFAT 770
Query: 833 GMYLVSC 839
G YL C
Sbjct: 771 GRYLADC 777
>gi|116235472 SH3-domain GRB2-like (endophilin) interacting protein
1 [Homo sapiens]
Length = 828
Score = 312 bits (800), Expect = 7e-85
Identities = 201/548 (36%), Positives = 288/548 (52%), Gaps = 47/548 (8%)
Query: 299 FDDEEPRKFYVHIKPAP-ARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAG 357
F D P + P +P +P+ A + A + PPGP G G
Sbjct: 315 FSDTSPEHVTPELTPREKVVSPPATPDNPAD---SPAPGPLGPPGPTGP---------PG 362
Query: 358 KPQRPRS--APRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFS 415
P PR+ +P ++ +E+ K+ + LE+ +DF LG ++P P
Sbjct: 363 PPGPPRNVLSPLNLEEVQKKVAEQTFIKDDY---LETISSPKDF----GLGQRATPPP-- 413
Query: 416 SSSPENVEDSGLDSPSHAA-PGPSPDSWVPRPGTPQSP-PSCRAPPPEARGIRAPPLPDS 473
P + + SP + PGP S P P +P CR+ P PP P
Sbjct: 414 --PPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPP------PPPPRP 465
Query: 474 PQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRS 533
P PG G+ GD+ P P + PP +R S S LS +
Sbjct: 466 PSRPKLPPGKPGV-----GDVS-RPFSPPIHSS-SPPPIAPLARAESTSSISSTNSLSAA 518
Query: 534 LSPSPLGSSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGH 593
+P+ + +R F T G SRGPSP+ +G+QD LP+A AFTE V+AYF+G
Sbjct: 519 TTPTVENEQPSLVWFDRGKFYL-TFEGSSRGPSPLTMGAQDTLPVAAAFTETVNAYFKGA 577
Query: 594 SPS-CLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQ 652
PS C+ ++TGE+ ++FPAGI R F+ P P L+FR+++ + +EH PN LL D +Q
Sbjct: 578 DPSKCIVKITGEMVLSFPAGITRHFANNPSPAALTFRVINFSRLEHVLPNPQLLCCDNTQ 637
Query: 653 SDPETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCG 712
+D TK+FW+NM L L++ +EQ P A+YYNV +L+YQ S G QS PL L+ +W+C
Sbjct: 638 NDANTKEFWVNMPNLMTHLKKVSEQKPQATYYNVDMLKYQVSAQGIQSTPLNLAVNWRCE 697
Query: 713 ATLTQVSVEYGYRPGATAVPTPLTNVQILLPVGEPVTNVR-LQPAATWNLEEKRLTWRLP 771
+ T + ++Y Y A L NVQ L+P+ VT ++ + P A WN E++R+ W++P
Sbjct: 698 PSSTDLRIDYKYNTDAMTTAVALNNVQFLVPIDGGVTKLQAVLPPAVWNAEQQRILWKIP 757
Query: 772 DV---SEAGGSGRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKR 828
D+ SE GG G L A ++ GPS PSP+ QFTSEG+TLSG D+ELVG+GYR SL+K+
Sbjct: 758 DISQKSENGGVGSLLARFQLSEGPSKPSPLVVQFTSEGSTLSGCDIELVGAGYRFSLIKK 817
Query: 829 RFATGMYL 836
RFA G YL
Sbjct: 818 RFAAGKYL 825
Score = 84.3 bits (207), Expect = 4e-16
Identities = 81/294 (27%), Positives = 127/294 (43%), Gaps = 40/294 (13%)
Query: 268 PEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAA 327
PE+DEEG+++RP+ ST +SSS+S+ ++E +KF + IKP ++ A
Sbjct: 79 PELDEEGYSIRPE-EPGSTKGKHFYSSSESEEEEESHKKFNIKIKPLQSK-DILKNAATV 136
Query: 328 AQLRATAGSLILPPGP--------GGTMKRHSSRDAAGKPQRPRSAPRTSSCAERLQSEE 379
+L+A+ G++ L P P G +KR+ S + +P+R S P +++ +
Sbjct: 137 DELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRR--STPTPELISKKPPDDT 194
Query: 380 QVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSP 439
LFGPPLESAFD + + P + S P N ++SP P P
Sbjct: 195 TALAPLFGPPLESAFDEQ-----KTEVLLDQPEIWGSGQPIN---PSMESPKLTRPFP-- 244
Query: 440 DSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPD---SPQPLASSPGPWGLEALAGGDLMP 496
+ P P P++ P+ PP + P D + + P L+++ G L P
Sbjct: 245 -TGTPPPLPPKNVPA--TPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSP 301
Query: 497 APADPTAREGL----------AAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG 540
A E P R + VS P T N + S +P PLG
Sbjct: 302 KSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNP--ADSPAPGPLG 353
>gi|20149528 proline-serine-threonine phosphatase interacting
protein 1 [Homo sapiens]
Length = 416
Score = 69.3 bits (168), Expect = 1e-11
Identities = 47/235 (20%), Positives = 115/235 (48%), Gaps = 18/235 (7%)
Query: 1 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH 60
+ ++++ A T + + ++ + + + H++L L++ ++ + + E Q +
Sbjct: 57 LVQIARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQR 116
Query: 61 KKCKEEVVSTLDAVQVLS-GVSQLLPKSRENYLNRCMD----QERLRRESTS--QKEMDK 113
KK + + +D VQ + + +S++ Y +C D ++ R S + QK+++K
Sbjct: 117 KKYE----AVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEK 172
Query: 114 AETKTKKAAESL-------RRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLG 166
++ K ++ +S R+S+ + RA++EQ+ + FQ E L ++ L
Sbjct: 173 SQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALW 232
Query: 167 SYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAY 221
+++ + V+ +++EE + +E S++ + F ++K TG E P P+ ++ Y
Sbjct: 233 VHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNY 287
>gi|165905601 proline-serine-threonine phosphatase interacting
protein 2 [Homo sapiens]
Length = 334
Score = 61.2 bits (147), Expect = 4e-09
Identities = 48/250 (19%), Positives = 113/250 (45%), Gaps = 21/250 (8%)
Query: 22 EVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVSTLDAVQVLSGVS 81
EVF+ D +A CH++L + L++ + + + E+Q K +K E ++ + + L
Sbjct: 78 EVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQ-KLQRKKTELIMDAIHKQKSLQFKK 136
Query: 82 QLLPKSRENYLNRCMDQERLRREST------SQKEMDKAETKTKKAAESLRRSVEKY--- 132
+ +++NY +C D++ + + + K+ +K K + ++ S + Y
Sbjct: 137 TM--DAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLH 194
Query: 133 ----NSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQ 188
+ R +++ + + + F+A E + + L + + + V +++E+ ++
Sbjct: 195 IGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEMYEQVRK 254
Query: 189 NIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRRE 248
++E S++ + F + TG+ P P+ +E + + K A P L+RR
Sbjct: 255 SLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENF-----YSSQKNAVPAGKATGPNLARRG 309
Query: 249 REPEPPAAVD 258
P P ++ D
Sbjct: 310 PLPIPKSSPD 319
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 55.5 bits (132), Expect = 2e-07
Identities = 141/575 (24%), Positives = 204/575 (35%), Gaps = 77/575 (13%)
Query: 253 PPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVHIK 312
PP V P S T P + + Q +T+ S + F PR+ +
Sbjct: 387 PPIQV----PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLT 442
Query: 313 PAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCA 372
+P+R + P++ Q L LP P + P SS A
Sbjct: 443 -SPSRPASTPPDSPPLQ-----APLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLA 496
Query: 373 ERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVED--SGLDSP 430
S + +L PPLE+ SSL S +P +S + +E+ S P
Sbjct: 497 SH--SPQAPLSSLIMPPLET---------QSSLAPPSLQTPPASLTTPPLENLPSLAPPP 545
Query: 431 SHAAPGPSPDSWVPRPGTP-----QSPPS-CRAPPPEARGIRAPPLPDSPQPLASSPGPW 484
A P + P P Q+PPS PPPE A P P +P LAS P
Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP--- 602
Query: 485 GLEALAGGDLMP-APADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSA 543
L+ L L P A P A LA PP + + P ++ LS +PSP +A
Sbjct: 603 -LQGLPSPPLSPLATPPPQAPPXLALPPLQ------APPSPPASPPLSPLATPSPQAPNA 655
Query: 544 ASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTG 603
+ L + F V SP S P AT ++ +P LA
Sbjct: 656 LAVHLLQAPFSPPPSPPVQAPFSPP--ASPPVSPSATPPSQ---------APPSLAAPPL 704
Query: 604 ELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLN 663
++ + PA S TPPP + P + + PS + P
Sbjct: 705 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPM--SPSATPPP------R 756
Query: 664 MAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQC-GATLTQVSVEY 722
+ L A Q +P AS L ++P PQ+ P + Q + +
Sbjct: 757 VPPLLAAPPLQVPPSPPAS-----LPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQA 811
Query: 723 GYRPGATAVPTPLTNVQILLP--VGEPVTNVRLQPAATWNLE-EKRLTWRLPDVSEAGGS 779
+ P A+ +PL P + P+ V P A+ L+ +R PD S +G
Sbjct: 812 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG-- 869
Query: 780 GRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDL 814
RL+ + P GP P S +TLSG DL
Sbjct: 870 PRLTLALAP--GPPPPPS-----RSPSSTLSGPDL 897
Score = 52.0 bits (123), Expect = 2e-06
Identities = 88/353 (24%), Positives = 124/353 (35%), Gaps = 55/353 (15%)
Query: 206 KGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRREREPEPPAAVDFLEPDSG 265
+ +G +PGPL + +A +E + R + +A + LS R SG
Sbjct: 119 RASGTTRPGPLGQKGLRISA-EETVARGKATEAPKRSALSAGARRDT-----------SG 166
Query: 266 TCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYV----HIKPAPARAPAC 321
P R P S+ E PRK H P+ A
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
Query: 322 SPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCAERLQSEEQV 381
P A R + SL P + R S A G P+ P + + QV
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPAR-SGPSARGTPRAPAHPSQPKPKGLQALRPPQV 285
Query: 382 SKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSPDS 441
+ PP + A + +LG SS SP ++ SP S + A P P PD+
Sbjct: 286 T-----PPRKDA--------APALGPLSS-SPLATPSP---------SGTKARPVPPPDN 322
Query: 442 WV-PRPGT-PQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPA 499
P P T P SPP P APP P +P L + P P A P+
Sbjct: 323 AATPLPATLPPSPPLATPLP------LAPPSPSAPPSLQTLPSP---PATPPSQAPPSMT 373
Query: 500 DPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALERPS 552
P + APP + P + ++ L SP L S A+T+L P+
Sbjct: 374 TPP----MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPT 422
Score = 48.5 bits (114), Expect = 3e-05
Identities = 74/294 (25%), Positives = 100/294 (34%), Gaps = 44/294 (14%)
Query: 302 EEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKP-Q 360
+ P VH+ AP P P A A+ P P T + A P Q
Sbjct: 651 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP-----PVSPSATPPSQAPPSLAAPPLQ 705
Query: 361 RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE 420
P S P + + Q L PPL+ +SP S++P
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPP-----------ASPPMSPSATPP 754
Query: 421 NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS 480
L +P P PSP + +P + PP +APP + PPL P P AS
Sbjct: 755 PRVPPLLAAPPLQVP-PSPPASLPMSPLAKPPP--QAPP----ALATPPLQALPSPPASF 807
Query: 481 PGPWGLEALAGGDLMP-APADPTAREGLAAP----------------PRRLRSRKVSCPL 523
PG A + P A P A LAAP PRR + +
Sbjct: 808 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 867
Query: 524 TRSNGDLSRSLSPSPLGSSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALP 577
+ L+ + P P S + S+ L P GH S +P L D+ P
Sbjct: 868 SGPRLTLALAPGPPPPPSRSPSSTLSGPDL---AGHSSSATSTPEELRGYDSGP 918
Score = 34.7 bits (78), Expect = 0.38
Identities = 48/189 (25%), Positives = 65/189 (34%), Gaps = 46/189 (24%)
Query: 314 APARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCAE 373
AP R P P+ + + R T L L PGP P P +P
Sbjct: 854 APRRPPTPGPDTSVSGPRLT---LALAPGP---------------PPPPSRSP------- 888
Query: 374 RLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHA 433
S L GP L T G+ S P +++SP + P+
Sbjct: 889 --------SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 940
Query: 434 APGPSPD-SWVPRPGTPQSPPSCRAPPPEARGI----------RAPPLPDSPQPLASSPG 482
+ GP+P ++ PG P P P A G+ A P P + P SPG
Sbjct: 941 SRGPAPPLAFRGAPGAPLPWPPATG-PGSADGLCTIYETEGPESATPAPGALDP-GPSPG 998
Query: 483 PWGLEALAG 491
G +A AG
Sbjct: 999 TSGGKAAAG 1007
Score = 34.3 bits (77), Expect = 0.49
Identities = 57/245 (23%), Positives = 80/245 (32%), Gaps = 61/245 (24%)
Query: 424 DSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPP----------------------E 461
D+ D A +P + P TP+ P S R PPP
Sbjct: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER 61
Query: 462 ARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSC 521
A GI +P+S A GP + PA P + G APP
Sbjct: 62 AGGIGGATIPES----APRAGP--TRSAGTSSRNPASRPPASGRGERAPP---------- 105
Query: 522 PLTRSNGDLSRSLSPSPLGSSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATA 581
+++ SP P+ S ++ RP L Q G +S V G P +A
Sbjct: 106 ---------AKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS-AEETVARGKATEAPKRSA 155
Query: 582 FTEYVHAYFRGHSPSC-------LARVTG-ELTMTFPAGIVRVFSGTPPPPVLSFRLVHT 633
+ G +P +R G E+ + PA S P PP R +
Sbjct: 156 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP-----SARPRPPTEGPRKSVS 210
Query: 634 TAIEH 638
+A EH
Sbjct: 211 SASEH 215
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 55.1 bits (131), Expect = 3e-07
Identities = 71/238 (29%), Positives = 93/238 (39%), Gaps = 32/238 (13%)
Query: 348 KRHSSRDAAGKPQ---RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFD--------- 395
+RH SR + K + + + P T S R S S + P L S +
Sbjct: 222 RRHRSRSSKCKRKEKNKEKKRPHTESPGRR--SHRHSSGSSHSPSLSSHYSDSRSPSRLS 279
Query: 396 --HEDF---TGSSSLGFTSSPSPFSSS---SPENVEDSGLDSPSHAAPGPSPDSWVPRPG 447
H D TGS + SPSP S SP+ SG S +H S S +P
Sbjct: 280 PKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPS 339
Query: 448 TP----QSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEA-LAGGDLMPAPADPT 502
+P + + AP P ARG +P SP+ SS G G A AG
Sbjct: 340 SPSPRVRDKAAAAAPTPPARGKESP----SPRSAPSSQGRGGRAAGGAGRRRRRRRRRRR 395
Query: 503 AREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALERPSFLSQTGHG 560
+R +AP RR R R P S+ LSR+ S S GS + P S+ GHG
Sbjct: 396 SRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPG-PGPEPGSERGHG 452
Score = 33.1 bits (74), Expect = 1.1
Identities = 63/261 (24%), Positives = 84/261 (32%), Gaps = 35/261 (13%)
Query: 312 KPAPARAPACSPEAAAAQLRATAGSLILPPGPG---GTMKRHSSRDAAGKPQRPRSAPRT 368
+P PA S + A+ + +GS PGPG G+ + H K + PR+ P +
Sbjct: 410 RPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPAS 469
Query: 369 SSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLD 428
+S P A S + P P S SS + S
Sbjct: 470 TS------------------PSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSR 511
Query: 429 SPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLAS--SPGPWGL 486
S PS +P + RA EA RA S P+ P +
Sbjct: 512 SAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFM 571
Query: 487 EALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAAST 546
E P T+ P R S L+ S S SPSP G S S
Sbjct: 572 E----------PRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSP-GHSHGSY 620
Query: 547 ALERPSFLSQTGHGVSRGPSP 567
+ S+T SR PSP
Sbjct: 621 SSRSHGTRSRT-RSPSRTPSP 640
>gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens]
Length = 412
Score = 53.9 bits (128), Expect = 6e-07
Identities = 49/213 (23%), Positives = 96/213 (45%), Gaps = 19/213 (8%)
Query: 1 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKL-QDLIKDVLRYGEEQLKT 59
+AKLS+ + G+ W + S A HL+ + KL ++ K ++ + E K
Sbjct: 191 LAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKD 250
Query: 60 HKKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------RLRRESTSQKEMDK 113
KKC + D + L+ + K+R+ R D E ++ + +++++ K
Sbjct: 251 MKKCDHHIA---DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKK 307
Query: 114 AETKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVE 173
A K+ +A + L R V+ YN A++ + ++M+ + L + +E + ++ L Y
Sbjct: 308 ARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRH 367
Query: 174 DTHVQIGQVHEEFKQNIENVSVEMLLRKFAESK 206
+T + F Q+ V+ LLRK +K
Sbjct: 368 ET--------DMFNQSTVE-PVDQLLRKVDPAK 391
>gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]
Length = 476
Score = 53.9 bits (128), Expect = 6e-07
Identities = 49/213 (23%), Positives = 96/213 (45%), Gaps = 19/213 (8%)
Query: 1 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKL-QDLIKDVLRYGEEQLKT 59
+AKLS+ + G+ W + S A HL+ + KL ++ K ++ + E K
Sbjct: 255 LAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKD 314
Query: 60 HKKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------RLRRESTSQKEMDK 113
KKC + D + L+ + K+R+ R D E ++ + +++++ K
Sbjct: 315 MKKCDHHIA---DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKK 371
Query: 114 AETKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVE 173
A K+ +A + L R V+ YN A++ + ++M+ + L + +E + ++ L Y
Sbjct: 372 ARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRH 431
Query: 174 DTHVQIGQVHEEFKQNIENVSVEMLLRKFAESK 206
+T + F Q+ V+ LLRK +K
Sbjct: 432 ET--------DMFNQSTVE-PVDQLLRKVDPAK 455
>gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens]
Length = 416
Score = 53.9 bits (128), Expect = 6e-07
Identities = 49/213 (23%), Positives = 96/213 (45%), Gaps = 19/213 (8%)
Query: 1 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKL-QDLIKDVLRYGEEQLKT 59
+AKLS+ + G+ W + S A HL+ + KL ++ K ++ + E K
Sbjct: 195 LAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKD 254
Query: 60 HKKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------RLRRESTSQKEMDK 113
KKC + D + L+ + K+R+ R D E ++ + +++++ K
Sbjct: 255 MKKCDHHIA---DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKK 311
Query: 114 AETKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVE 173
A K+ +A + L R V+ YN A++ + ++M+ + L + +E + ++ L Y
Sbjct: 312 ARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRH 371
Query: 174 DTHVQIGQVHEEFKQNIENVSVEMLLRKFAESK 206
+T + F Q+ V+ LLRK +K
Sbjct: 372 ET--------DMFNQSTVE-PVDQLLRKVDPAK 395
>gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens]
Length = 336
Score = 53.9 bits (128), Expect = 6e-07
Identities = 49/213 (23%), Positives = 96/213 (45%), Gaps = 19/213 (8%)
Query: 1 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKL-QDLIKDVLRYGEEQLKT 59
+AKLS+ + G+ W + S A HL+ + KL ++ K ++ + E K
Sbjct: 115 LAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKD 174
Query: 60 HKKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------RLRRESTSQKEMDK 113
KKC + D + L+ + K+R+ R D E ++ + +++++ K
Sbjct: 175 MKKCDHHIA---DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKK 231
Query: 114 AETKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVE 173
A K+ +A + L R V+ YN A++ + ++M+ + L + +E + ++ L Y
Sbjct: 232 ARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRH 291
Query: 174 DTHVQIGQVHEEFKQNIENVSVEMLLRKFAESK 206
+T + F Q+ V+ LLRK +K
Sbjct: 292 ET--------DMFNQSTVE-PVDQLLRKVDPAK 315
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 53.9 bits (128), Expect = 6e-07
Identities = 94/377 (24%), Positives = 131/377 (34%), Gaps = 96/377 (25%)
Query: 247 REREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDF---DDEE 303
+E EP PP D + G PE + E T + + + EP R + S
Sbjct: 437 KEAEPTPPVLPDEEKGPPGPAPEPEREAET---EPERGAGTEPERIGTEPSTAPAPSPPA 493
Query: 304 PRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDA-AGKPQRP 362
P+ H A + PA SP AAA+ S + PGPG S DA A P+RP
Sbjct: 494 PKSCLKHRPAAASEGPAASPPLAAAE------SPPVEPGPG-------SLDAEAAAPERP 540
Query: 363 RS--APRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSS-----------LGFTS 409
++ A + AER E + + G L A + F+ SS L S
Sbjct: 541 KAERAEAPPAGAERAAPERKAERG--GAELRGA---KKFSVSSCRARPRPGVSRPLERAS 595
Query: 410 SPSPFSSSSPENVEDSGLDS------PSHAAPGP-----------------------SPD 440
P + S P ++ LD P HA PGP SP
Sbjct: 596 GRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQ 655
Query: 441 SWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPAD 500
PGT + P+ + P AP +P P+ L
Sbjct: 656 EAAAAPGTREPCPAAQEP--------APSEDRNPFPV---------------KLRSTSLS 692
Query: 501 PTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALERPSFLSQTGHG 560
R+G + + ++ L RS L + PLG++ A P S G G
Sbjct: 693 LKYRDGASQEVKGVKRYSAEVRLERSLTVLPKE-EKCPLGTAPALRGTRAP---SDQGKG 748
Query: 561 VSRGPSPVVLGSQDALP 577
+R P P L S+ LP
Sbjct: 749 KARPPEP--LSSKPPLP 763
Score = 47.0 bits (110), Expect = 7e-05
Identities = 57/223 (25%), Positives = 80/223 (35%), Gaps = 25/223 (11%)
Query: 315 PARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCAER 374
PA PE+A LR S P GP +D P P AP T E
Sbjct: 336 PATPELAEPESAPT-LRVEPPSP--PEGPPNPGPDGGKQDGEAPPAGP-CAPATDKAEEV 391
Query: 375 LQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE-NVEDSGLDSP--- 430
+ + E V+ P +A D T + +S +P + PE +V +P
Sbjct: 392 VCAPEDVAS-----PFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVL 446
Query: 431 ---SHAAPGPSPD-----SWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDS---PQPLAS 479
PGP+P+ P G P P A +PP P S +P A+
Sbjct: 447 PDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPA-PSPPAPKSCLKHRPAAA 505
Query: 480 SPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCP 522
S GP LA + P P + + AA P R ++ + P
Sbjct: 506 SEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAP 548
Score = 32.7 bits (73), Expect = 1.4
Identities = 37/136 (27%), Positives = 52/136 (38%), Gaps = 19/136 (13%)
Query: 415 SSSSPENVEDSGLDSPSHAAPGPSPDSW--VPRPGTPQSPPSCRAPPPEARGIRAPPLPD 472
SS+ +VE+ G+ PG P S P P+S P+ R PP P PD
Sbjct: 315 SSALTASVEEGGV-------PGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPD 367
Query: 473 SPQPLASSP--GPWGLEALAGGDLMPAPAD-----PTA-REGLAAPPRRLRSRKVSCPLT 524
+ +P GP +++ AP D PTA EG PP + P
Sbjct: 368 GGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSA 427
Query: 525 RSNGDLS--RSLSPSP 538
R + S + P+P
Sbjct: 428 RDGPERSVPKEAEPTP 443
Score = 30.8 bits (68), Expect = 5.5
Identities = 57/260 (21%), Positives = 81/260 (31%), Gaps = 35/260 (13%)
Query: 313 PAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKR--HSSRDAAGKPQRPRSAPRTSS 370
P P EAA L+ PGP +R S D A P PR +P+ ++
Sbjct: 599 PLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAA 658
Query: 371 --------CAERLQSEEQVSKNLFGPPLES---AFDHEDFTGSSSLGFTSSPSPFSSSSP 419
C + +N F L S + + D G +
Sbjct: 659 AAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERS 718
Query: 420 ENVEDSGLDSPSHAAPG----PSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQ 475
V P AP +P P P S + P P +++ LP P
Sbjct: 719 LTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPA 778
Query: 476 PLASSPG------------PWGLEALAGGDLMPAPADPTAREGLAAPP-----RRLRSRK 518
P + PG L A L PA P A +G APP R+ R
Sbjct: 779 PPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGA-DGQPAPPWITVTRQKRRGT 837
Query: 519 VSCPLTRSNGDLSRSLSPSP 538
+ P + + +R+L P
Sbjct: 838 LDQPPNQEDKPGARTLKSEP 857
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 53.9 bits (128), Expect = 6e-07
Identities = 84/360 (23%), Positives = 117/360 (32%), Gaps = 50/360 (13%)
Query: 223 AAALQEAMKRLRGAKAFRLPGLSRREREPEP-----PAAVDFLEPDSGTCPEVDEEGFTV 277
A+ L E +G+K P + P P P+AV L P T P + T
Sbjct: 833 ASFLPENSLSFQGSKDS--PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKE----TP 886
Query: 278 RPDVT-----QNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPAC-SPEAAAAQLR 331
P V + A P+ + P+K PAP PA SP+ A
Sbjct: 887 TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK--ARATPAPKGIPASPSPKGAPTPPA 944
Query: 332 ATAGS-----------------LILPPGPGGTMKRHSSRDA----AGKPQRPRSAPRTSS 370
AT S PP P G S + A A P P+ P T S
Sbjct: 945 ATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPS 1004
Query: 371 CAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSP 430
+ G P + F G+S+ + PSP S + + +P
Sbjct: 1005 PKGAPTPPAVTPPSPKGSPAATPFPK----GASTPPAATPPSPKGSPAATPLPKGAPTTP 1060
Query: 431 SHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEAL- 489
+ P P P +PP+ P P+ P P A+ P P G A
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120
Query: 490 --AGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTA 547
G PA P+ + GLA PP + + G L+ +P P G+ A
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA---TPPPKGAPTTPAA 1177
Score = 48.5 bits (114), Expect = 3e-05
Identities = 56/219 (25%), Positives = 79/219 (36%), Gaps = 20/219 (9%)
Query: 313 PAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCA 372
P+P +PA +P A A GP + + A P P+ P T S
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100
Query: 373 ER----LQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSS-SSPENVEDS-- 425
+ L PP + A T S G ++P P + ++P S
Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160
Query: 426 -GLDSP-------SHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDS--PQ 475
GL +P + AA PSP + P +P + A PP +G A P P
Sbjct: 1161 GGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1220
Query: 476 PLASSPGPWG---LEALAGGDLMPAPADPTAREGLAAPP 511
P A+ P P G + G PA P+ + G A PP
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP 1259
Score = 45.1 bits (105), Expect = 3e-04
Identities = 67/325 (20%), Positives = 109/325 (33%), Gaps = 41/325 (12%)
Query: 282 TQNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAP----ACSPEAAAAQLRATAGSL 337
T++S A + S + + P V + P R P + P+ L + +
Sbjct: 772 TEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPV 831
Query: 338 ILPPGPGGTMKRHSSRDAAGK-----PQRPRSAPRTSSCAE------RLQSEEQVSKNLF 386
P ++ S+D+ P P+ AP S+ L +E + ++
Sbjct: 832 EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVV 891
Query: 387 -------GPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSP 439
GP + + +SS + +P P + G +P A P PSP
Sbjct: 892 NLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP-PSP 950
Query: 440 DSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQ--PLASSPGPWGLEALA---GGDL 494
P +P A PP +G A P P P A+ P P G A G
Sbjct: 951 KGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPT 1010
Query: 495 MPAPADPTAR---------EGLAAPPRRL----RSRKVSCPLTRSNGDLSRSLSPSPLGS 541
PA P+ + +G + PP + + PL + + PSP G
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG 1070
Query: 542 SAASTALERPSFLSQTGHGVSRGPS 566
A + P+ + T GP+
Sbjct: 1071 PATPSLKGAPTPPAATPPSPKGGPA 1095
Score = 43.1 bits (100), Expect = 0.001
Identities = 59/221 (26%), Positives = 79/221 (35%), Gaps = 44/221 (19%)
Query: 313 PAPARAPAC-SPEAAAAQLRATA----GSLILPPGPGG----TMKRHSSRDAAGKPQRPR 363
P+P PA SP+ A AT G L PP G S + P P+
Sbjct: 1088 PSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP-PK 1146
Query: 364 SAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSS-SSPENV 422
AP T + + L PP + A T S G ++PSP + ++P
Sbjct: 1147 GAPTTPAA-----TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201
Query: 423 EDS---GLDSPSH-------AAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPD 472
S GL +PS AA PSP + P +P + A PP +G A P P
Sbjct: 1202 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPP- 1260
Query: 473 SPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRR 513
G PA P+ + GLA PP +
Sbjct: 1261 -----------------KGAPTPPAATPPSLKGGLATPPHK 1284
Score = 42.7 bits (99), Expect = 0.001
Identities = 61/266 (22%), Positives = 92/266 (34%), Gaps = 37/266 (13%)
Query: 313 PAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCA 372
P+P +P P A A + PP P GT ++ ++ + P T S
Sbjct: 1318 PSPKGSPGTPPPKGAPTPPA-----VTPPSPKGTPTLPATTPSS------KGGPTTPSSK 1366
Query: 373 ERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPEN----VEDSGLD 428
E + GP + S G +SP+ S + V G
Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAA 1426
Query: 429 SPSHAAPGP----------SPDSWVPR--PGTPQSPPSCRAPPPEARGIRAPPLP----- 471
+PS P +P + P+ P TP S P + PP P
Sbjct: 1427 TPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVAT 1486
Query: 472 -DSPQPLASSPGPWG---LEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSN 527
SP+ ++P P G L A+ PA P++R AP L S+K L
Sbjct: 1487 SSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKE 1546
Query: 528 GDLSRSLS-PSPLGSSAASTALERPS 552
+ +++ PSP + A T E P+
Sbjct: 1547 ALIPPAMTVPSPKKTPAIPTPKEAPA 1572
Score = 42.4 bits (98), Expect = 0.002
Identities = 63/259 (24%), Positives = 93/259 (35%), Gaps = 53/259 (20%)
Query: 322 SPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDA----AGKPQRPRSAPRTSSCAERLQS 377
SP+ A AT PP P G + S + A A P P+ P T
Sbjct: 1213 SPKGAPTTPAAT------PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP-----PK 1261
Query: 378 EEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGP 437
P L+ G+ + + PSP P G +P A P P
Sbjct: 1262 GAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP--KGGPATSPPKGAPTPPAATP-P 1318
Query: 438 SPDSWVPRPGTPQSPPSCRAPPPEA--------------------RGIRAPPLPDSPQPL 477
SP G+P +PP AP P A G P + P P
Sbjct: 1319 SPK------GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPP 1372
Query: 478 ASSPGPWGLEALA-----GGDLMPAP-ADPTAREGLAAPPRRLRSRKVS--CPLTRSNGD 529
A++P G A+ G +P+P DPT+ + P++ + V+ T S GD
Sbjct: 1373 AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432
Query: 530 LS-RSLSPSPLGSSAASTA 547
L+ +++P L + A++A
Sbjct: 1433 LTPPAVTPVSLKKAPATSA 1451
Score = 40.4 bits (93), Expect = 0.007
Identities = 62/251 (24%), Positives = 89/251 (35%), Gaps = 27/251 (10%)
Query: 302 EEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQR 361
E P V +P +APA A L A ++P P SSR R
Sbjct: 1477 EPPAPKQVATSSSPKKAPATPAPMGAPTLPA-----VIPSSPKEVPATPSSR-------R 1524
Query: 362 PRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPEN 421
AP + +++ + + L P + + + ++PS +SSP
Sbjct: 1525 DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA 1584
Query: 422 VEDS---GLDSPSH-----AAPGPSP-DSWVPRPGTPQSPPSCRAPPPEARGIRAPP--- 469
V S G SP A PSP ++ P TP SP A P +PP
Sbjct: 1585 VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTP 1644
Query: 470 --LPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSN 527
L DSP AS G +PA PTA + + P + ++ P TR
Sbjct: 1645 SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAP-TRKG 1703
Query: 528 GDLSRSLSPSP 538
+S + SP
Sbjct: 1704 PQTKKSSATSP 1714
Score = 34.3 bits (77), Expect = 0.49
Identities = 120/597 (20%), Positives = 202/597 (33%), Gaps = 124/597 (20%)
Query: 249 REPEPPAAVDFLEPDSGTCPEVDE---------EGFTVRPDV-TQNSTAEPSRFSSSDSD 298
+EP A P S P+ ++ F + D+ T ++ E + FS + +
Sbjct: 491 KEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAG 550
Query: 299 FDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAA-- 356
++ ++ AP +P+ ++T+ S +P P T+ + S +
Sbjct: 551 LTTKKDPTVLPLVQAAPKNSPS---------FQSTSSSPEIPLSPEATLAKKSLGEPLPI 601
Query: 357 GKPQRPRSAPR-TSSCAERLQSEEQVSKNLFGPPLES--------AFDHEDF-------- 399
GKP ++P +S A ++++ + GP L+S AF E
Sbjct: 602 GKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPT 661
Query: 400 TGSSSLGFTSSPSPFS----SSSPEN--VEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPP 453
T + +T++ SPF S +P+N V++ L + P P +P
Sbjct: 662 TAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPL 721
Query: 454 SCRAPPPEA-RGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPR 512
+ PE + + +P LP P + PG ++ ++ +A +A+ P+
Sbjct: 722 ATLVLAPEIPKSVPSPSLP----PAGTPPGTKKVDGIS---------HTSALAPVASSPK 768
Query: 513 RLRSRKVSCPLTRSNGDLSRSL--SPSPLGSSAASTALERPSFLSQTGHGVSRGPSPVVL 570
+ T S+ L SPSPLG S + P T G + +P+
Sbjct: 769 ECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPP-----TKKGSAGPDTPIGN 823
Query: 571 GSQDALPIATAFTEYVHAYFRGHSPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRL 630
S P+ +F F+G S PA S TPP P +
Sbjct: 824 LSSPVSPVEASFLPENSLSFQGSKDS-------------PA---TTHSPTPPSPKGA--- 864
Query: 631 VHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLR 690
PS P + + + ++ PT S N+ +
Sbjct: 865 -----------------PTPSAVTPLSP----------KGVTLPPKETPTPSVVNLPFPK 897
Query: 691 YQFSRPGPQSVP-LQLSAHWQCGATLTQVSVEYGYRPGATAVPTPLTNVQILLPVGEPVT 749
+ P P+ P L +++ A T P PTP P G P T
Sbjct: 898 EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS-PKGGPAT 956
Query: 750 NVRLQPAATWNLEEKRLTWRLPDVSEAGGSGR------LSASWEPLSGPSTPSPVAA 800
P+ W T P A S + + P GP+TPSP A
Sbjct: 957 -----PSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGA 1008
Score = 32.7 bits (73), Expect = 1.4
Identities = 43/177 (24%), Positives = 67/177 (37%), Gaps = 14/177 (7%)
Query: 311 IKPAPARAPACSPEAAAAQLRATA--GSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRT 368
+ P+ + SP + ++ AT S LP G T + A P S P
Sbjct: 1642 VTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPA-----PESTPII 1696
Query: 369 SSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLD 428
++ + ++ S PP+ D GS T +P+P ++ + +
Sbjct: 1697 TAPTRKGPQTKKSSAT--SPPI--CPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGK 1752
Query: 429 SPSHAAPGP--SPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGP 483
SH+ GP P+S P T + P PE+ + A P P PLA SP P
Sbjct: 1753 DASHSPKGPLAPPESKASTPLTAAAFEKV-LPKPESASVSAAPSPPVSLPLAPSPVP 1808
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 52.8 bits (125), Expect = 1e-06
Identities = 46/124 (37%), Positives = 53/124 (42%), Gaps = 21/124 (16%)
Query: 395 DHEDF-------TGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSPDSWVPRPG 447
DH+D G +S + P P +S P SGL S S A P P + P P
Sbjct: 623 DHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPP 682
Query: 448 TPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGL 507
P PP PPP + G PP P P PL +SP P GG P PA P GL
Sbjct: 683 PPPPPPP--LPPPSSAG---PPPPPPPPPLPNSPAP----PNPGG---PPPAPPP--PGL 728
Query: 508 AAPP 511
A PP
Sbjct: 729 APPP 732
Score = 32.3 bits (72), Expect = 1.9
Identities = 103/452 (22%), Positives = 152/452 (33%), Gaps = 104/452 (23%)
Query: 82 QLLPKSRENYLN--RCMDQERLRRESTSQ-KEMDKAETKTKKAAESLRRSVEKYNSARAD 138
++ PKS E L + + R+ +T+ E++ + K + ESLR E+ NS AD
Sbjct: 392 EVKPKSPETALEAFKALFIRPPRKGTTADTSELEALKRKMRHEKESLRAVFERSNSKPAD 451
Query: 139 FEQKMLDSALRFQAMEETHLRHMKALLGSYAH-SVEDTHVQIG-------------QVHE 184
DS ++ E R L + +DT ++G +
Sbjct: 452 GPS---DSKSPDHSLTEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKR 508
Query: 185 EFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGL 244
E K+ IEN+ + LR F +G A A L+E ++ L+ R G
Sbjct: 509 EHKEEIENLQAQFELRAF-HIRGE----------HAMITARLEETIENLKHELEHRWRG- 556
Query: 245 SRREREPEPPAAVDFLEPDS--GTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDE 302
ER+ + D P + C + D E F ++P +++ T ++
Sbjct: 557 GCEERKDVCISTDDDCPPKTFRNVCVQTDRETF-LKPCESESKTTRSNQLV--------- 606
Query: 303 EPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRP 362
P+K ++I +P + A L+ G +S P P
Sbjct: 607 -PKK--LNISSLSQLSPPNDHKDIHAALQPMEGM--------------ASNQQKALPPPP 649
Query: 363 RSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSP--- 419
S P PPL S G SL P S+ P
Sbjct: 650 ASIPPP-------------------PPLPS--------GLGSLSPAPPMPPVSAGPPLPP 682
Query: 420 ENVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLAS 479
L PS A P P P P P +P +PP+ PPP APP P LA
Sbjct: 683 PPPPPPPLPPPSSAGPPPPPPP-PPLPNSP-APPNPGGPPP------APP----PPGLAP 730
Query: 480 SPGPWGLEALAGGDLMPAPADPTAREGLAAPP 511
P P GL G P P P
Sbjct: 731 PPPP-GLFFGLGSSSSQCPRKPAIEPSCPMKP 761
>gi|239752265 PREDICTED: hypothetical protein XP_002348186 [Homo
sapiens]
Length = 225
Score = 51.6 bits (122), Expect = 3e-06
Identities = 50/155 (32%), Positives = 64/155 (41%), Gaps = 11/155 (7%)
Query: 416 SSSPENVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPP-LPDSP 474
S SP++V S P SPDS VP PG SP S PP + PP PDS
Sbjct: 52 SRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPG---SPDSVVLPPRSPDSVVPPPRSPDSV 108
Query: 475 QPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSL 534
P SP L + ++P P P + + PP RS P RS R+
Sbjct: 109 VPPPGSPDSVVLPPRSPDSVVPPPGSP---DSVVLPP---RSPDSVVPPARSPDSGGRAG 162
Query: 535 SPSPLGSSAASTALERPSFLSQTGH-GVSRGPSPV 568
SP L AA+ A P + + G ++R P V
Sbjct: 163 SPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQV 197
Score = 38.9 bits (89), Expect = 0.020
Identities = 63/226 (27%), Positives = 82/226 (36%), Gaps = 32/226 (14%)
Query: 319 PACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQR-PRSAPRTSSCAERLQS 377
P+ SP++ R+ S++LPPG S D+ P R P S + +
Sbjct: 21 PSRSPDSVVLPSRSP-DSVVLPPG---------SPDSVVLPSRSPDSVVPPPGSPDSVVL 70
Query: 378 EEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSP----SHA 433
+ ++ PP GS SP S P DS + P S
Sbjct: 71 PPRSPDSVVPPP-----------GSPDSVVLPPRSPDSVVPPPRSPDSVVPPPGSPDSVV 119
Query: 434 APGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGD 493
P SPDS VP PG SP S PP + P A SP A A +
Sbjct: 120 LPPRSPDSVVPPPG---SPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAE 176
Query: 494 LMPAPADPTAREGLAAPPRRLRSR--KVSCPLTRSNGDLSRSLSPS 537
P A R LA P ++ SR +S PL+ S L L PS
Sbjct: 177 GAPGWAGRWGRVPLARSPPQVPSRPPSLSQPLS-SRVSLYELLFPS 221
>gi|51702222 SPT2, Suppressor of Ty, domain containing 1 [Homo
sapiens]
Length = 685
Score = 50.8 bits (120), Expect = 5e-06
Identities = 122/527 (23%), Positives = 190/527 (36%), Gaps = 96/527 (18%)
Query: 76 VLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMD-KAETKTKKAAESLRRSVEKYNS 134
V S Q K +E L R +E+ R+E +K ++ K + K + A+ + + YN
Sbjct: 39 VQSAAVQAFLKRKEEELRRKALEEKRRKEELVKKRIELKHDKKARAMAKRTKDNFHGYNG 98
Query: 135 ARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVS 194
+ + K + QA E +H+ + T E++ EN
Sbjct: 99 IPIEEKSK------KRQATE--------------SHTSQGTD-------REYEMEEEN-- 129
Query: 195 VEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRREREPEPP 254
E L AES+ E+ P E+ L+ A + RL +++ EP
Sbjct: 130 -EFLEYNHAESEQEYEEEQEPPKVESKPKVPLKSAPPPMNFTDLLRLA--EKKQFEPVEI 186
Query: 255 AAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPA 314
V E T E+ E F R +K K
Sbjct: 187 KVVKKSEERPMTAEELREREFLERK----------------------HRRKKLETDGKLP 224
Query: 315 PARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCAER 374
P + + + + + GS P G H+ + + + +SS +
Sbjct: 225 PTVSKKAPSQKESVGTKLSKGSGDRHPSSKGMPLPHAEKKSRPSMANEKHLALSSSKSMP 284
Query: 375 LQSEEQVSKNLFGPPLESAFDHEDFTGSSSL-GFTSSPS-PFSSSSP------ENVEDSG 426
+ + S N P L D F G+ TSSPS P +S+S E+
Sbjct: 285 GERIKAGSGNSSQPSLREGHDKPVFNGAGKPHSSTSSPSVPKTSASRTQKSAVEHKAKKS 344
Query: 427 LDSPSHAAPGP--SPDSWVPRPGTPQ-SPPSCRAPPPEARGIRAPPLPDSPQPL----AS 479
L PSH+ PGP +P + PG Q S AP + G+ P + P P +S
Sbjct: 345 LSHPSHSRPGPMVTPHNKAKSPGVRQPGSSSSSAPGQPSTGVARPTVSSGPVPRRQNGSS 404
Query: 480 SPGPWGLEALAGGDLMPAPADPTAR--EGLAAPPRRLRSRKVSCPLTRSNG---DLSRSL 534
S GP +++G ++P+ R G P + P + S G +S S+
Sbjct: 405 SSGP--ERSISGSKKPTNDSNPSRRTVSGTCGPGQ---------PASSSGGPGRPISGSV 453
Query: 535 SPS-PLGSS-------AASTALERP-SFLSQTGHGVSRGPSPVVLGS 572
S + PLGSS ++ L RP S L G VS GP + GS
Sbjct: 454 SSARPLGSSRGPGRPVSSPHELRRPVSGLGPPGRSVS-GPGRSISGS 499
>gi|157743252 pecanex-like 3 [Homo sapiens]
Length = 2034
Score = 50.4 bits (119), Expect = 7e-06
Identities = 55/170 (32%), Positives = 66/170 (38%), Gaps = 38/170 (22%)
Query: 395 DHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPS 454
D D +G L S+ P + +PEN +G D P PG P S + G + PP
Sbjct: 1836 DDSDCSGGGGLTSLSNNPPVAHPTPENTAGNG-DQPLPPGPGWGPRSSLSGSGDGRPPPL 1894
Query: 455 CRAPPPEARGIRAPPLPDSPQP-------------LASSPGP---W---GLEALAGGDLM 495
+ PPP G P P SP P L SS GP W G + L G D
Sbjct: 1895 LQWPPPRLPG----PPPASPIPTEGPRTSRPPGPGLLSSEGPSGKWSLGGRKGLGGSDGE 1950
Query: 496 PAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAAS 545
PA P + K PL S LS SLS SP S+ AS
Sbjct: 1951 PASGSPKG-----------GTPKSQAPLDLS---LSLSLSLSPDVSTEAS 1986
Score = 30.4 bits (67), Expect = 7.1
Identities = 69/288 (23%), Positives = 99/288 (34%), Gaps = 35/288 (12%)
Query: 313 PAPARAPACSPEAAAAQLRATAGSLI----LPPGPGGTMKRHSSRDAAGKPQRPRSAPRT 368
P+ A + P A +GS + + P G++ + S+ Q R+ RT
Sbjct: 207 PSLASTDSSEPSPLAGDGAPWSGSSMADTPMSPLLKGSLSQELSKSFLTLTQPDRALVRT 266
Query: 369 SSCAERLQSE---EQVSKNLFGPPL-------ESAFDHEDFTGSSSLGFTSSPSPFSSSS 418
SS E+ + + + + G P +S F D SS + S S
Sbjct: 267 SSRREQRRGAGGYQPLDRRGSGEPTPQKAGSSDSCFSGTDRETLSSFKSEKTNSTHLDSP 326
Query: 419 PENV--EDSGLDSPSHAAPGPSPDSWVPRPGTPQS---------PPSCRAP----PPEAR 463
P E S D PS A SPD+ VP T +S PP P P+
Sbjct: 327 PGGPAPEGSDTDPPSEAELPASPDAGVPSDDTLRSFDTVIGAGTPPGLAEPLLVVRPKDL 386
Query: 464 GIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRS-RKVSCP 522
+ P P S PG L G D T+ +P LRS R+ S
Sbjct: 387 ALLRPSKRQPPLRRHSPPGRAPRRPLLEGGGFFEDED-TSEGSELSPASSLRSQRRYSTD 445
Query: 523 LTRSNG----DLSRSLSPSPLGSSAASTALERPSFLSQTGHGVSRGPS 566
+ S + SR + P A A E + + +G R PS
Sbjct: 446 SSSSTSCYSPESSRGAAGGPRKRRAPHGAEEGTAVPPKRPYGTQRTPS 493
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 50.4 bits (119), Expect = 7e-06
Identities = 85/341 (24%), Positives = 115/341 (33%), Gaps = 67/341 (19%)
Query: 333 TAGSLILPPG---PGGTMK------RHSSRDAAGKPQRPRSAPRTSSCAERLQSEEQVSK 383
+ G+ + P G GG +K + S + AGKP P + + A R
Sbjct: 76 SGGAALQPKGGLFQGGVLKLRPVGAKDGSENLAGKPAL--QIPSSRAAAPR--------- 124
Query: 384 NLFGPPLESAFDH-EDFTGSS-----SLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGP 437
PP+ +A +D T SS L PS S P +G+ S A P P
Sbjct: 125 ----PPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPP 180
Query: 438 SPDSWVPRPGTPQSPPSCRAPP-------PEARGIRAPP---LPDSPQPLASSPGPWGLE 487
P P TP S +AP P G R P P +P P+ P P +
Sbjct: 181 PPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNIR 240
Query: 488 ALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCP--------LTRSNGDLSRSLSPSPL 539
G + AP P R+ P S P L R R L+P P
Sbjct: 241 TGPSGQSL-APPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPP 299
Query: 540 GSSAASTALER--PSFLSQTGHGVSRGPSPVVL--GSQDALPIATAFTEYVHAYFRGHSP 595
S++ S R P G + P P V+ G++DA P + G P
Sbjct: 300 TSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYR------MHGSEP 353
Query: 596 SCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAI 636
+ P R +G PPPP R H +I
Sbjct: 354 PSRGKP--------PPPPSRTPAGPPPPPPPPLRNGHRDSI 386
>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
sapiens]
Length = 1235
Score = 50.1 bits (118), Expect = 9e-06
Identities = 55/203 (27%), Positives = 75/203 (36%), Gaps = 39/203 (19%)
Query: 437 PSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMP 496
P P P P PQ+ P RAP P+ ++ P P PL++ P EA L P
Sbjct: 298 PCPQVAQPIP-QPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEA----QLQP 352
Query: 497 APADPTAREGLAAPPRRL------------RSRKVSCPLTRSNGDLSRSLSPSPLGSSAA 544
AP R P +L ++ +S PL+ N S SLS + L SS +
Sbjct: 353 APQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYN---SSSLSLNSLSSSRS 409
Query: 545 STALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTGE 604
ST + H S P P+ L + L +FT + H P+ A T
Sbjct: 410 STPAKTQPAPPHISHHPSASPFPLSLPNHSPL---HSFTPTLQPPAHSHHPNMFAPPT-- 464
Query: 605 LTMTFPAGIVRVFSGTPPPPVLS 627
PPPP L+
Sbjct: 465 --------------ALPPPPPLT 473
>gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
sapiens]
Length = 1259
Score = 50.1 bits (118), Expect = 9e-06
Identities = 55/203 (27%), Positives = 75/203 (36%), Gaps = 39/203 (19%)
Query: 437 PSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMP 496
P P P P PQ+ P RAP P+ ++ P P PL++ P EA L P
Sbjct: 298 PCPQVAQPIP-QPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEA----QLQP 352
Query: 497 APADPTAREGLAAPPRRL------------RSRKVSCPLTRSNGDLSRSLSPSPLGSSAA 544
AP R P +L ++ +S PL+ N S SLS + L SS +
Sbjct: 353 APQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYN---SSSLSLNSLSSSRS 409
Query: 545 STALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTGE 604
ST + H S P P+ L + L +FT + H P+ A T
Sbjct: 410 STPAKTQPAPPHISHHPSASPFPLSLPNHSPL---HSFTPTLQPPAHSHHPNMFAPPT-- 464
Query: 605 LTMTFPAGIVRVFSGTPPPPVLS 627
PPPP L+
Sbjct: 465 --------------ALPPPPPLT 473
>gi|157074225 nuclear pore complex interacting protein-like 3 [Homo
sapiens]
Length = 678
Score = 50.1 bits (118), Expect = 9e-06
Identities = 69/256 (26%), Positives = 94/256 (36%), Gaps = 49/256 (19%)
Query: 311 IKPAPARAPACSPEAAAAQLRATAGSLI--LPPGPGGTMKRHSSRDAAGKPQR--PRSAP 366
+ P P A +P +A L+ A L+ LPP +K S R P P +
Sbjct: 347 LTPLPPSALPSAPPSADDNLKTRAECLLHPLPPSADDNLKTPSERQLTPLPPSAPPSADD 406
Query: 367 RTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSG 426
+ AERL+ GP SA D+ L +P S+P + +D+
Sbjct: 407 NIKTPAERLR----------GPLPPSADDNLKTPSERQL------TPLPPSAPPSADDN- 449
Query: 427 LDSPSHAAPGPSPDSWVPRPGTPQS------PPSCRAPPPEARGIRAP------PLPDSP 474
+ +P+ GP P S TP PPS APP I+ P PLP S
Sbjct: 450 IKTPAERLRGPLPPSADDNLKTPSERQLTPLPPS--APPSADDNIKTPAERLRGPLPPSA 507
Query: 475 QPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSL 534
+P L L P A P+A + + P RLR PL S D +L
Sbjct: 508 DDNLKTPSERQLTPL------PPSAPPSADDNIKTPAERLRG-----PLPPSADD---NL 553
Query: 535 SPSPLGSSAASTALER 550
PL + A R
Sbjct: 554 KTPPLATQEAEAEKPR 569
Score = 39.3 bits (90), Expect = 0.015
Identities = 60/246 (24%), Positives = 88/246 (35%), Gaps = 39/246 (15%)
Query: 310 HIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTS 369
++K P P +A L+ L+ P P + + P P + P
Sbjct: 300 NLKTPPECVLTPLPPSADDNLKTPPECLLTPLPPSADDNLKTPPECLLTPLPPSALPSAP 359
Query: 370 SCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDS 429
A+ + + ++ L P SA D+ L +P S+P + +D+ + +
Sbjct: 360 PSAD--DNLKTRAECLLHPLPPSADDNLKTPSERQL------TPLPPSAPPSADDN-IKT 410
Query: 430 PSHAAPGPSPDSWVPRPGTPQS------PPSCRAPPPEARGIRAP------PLPDSPQPL 477
P+ GP P S TP PPS APP I+ P PLP S
Sbjct: 411 PAERLRGPLPPSADDNLKTPSERQLTPLPPS--APPSADDNIKTPAERLRGPLPPSADDN 468
Query: 478 ASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGD-----LSR 532
+P L L P A P+A + + P RLR PL S D R
Sbjct: 469 LKTPSERQLTPL------PPSAPPSADDNIKTPAERLRG-----PLPPSADDNLKTPSER 517
Query: 533 SLSPSP 538
L+P P
Sbjct: 518 QLTPLP 523
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 49.7 bits (117), Expect = 1e-05
Identities = 73/314 (23%), Positives = 106/314 (33%), Gaps = 66/314 (21%)
Query: 276 TVRPDVTQNSTAEPSRFSSSDSDFDDEEPRK------FYVHIKPAPARAPACSPEAAAAQ 329
T + D+ + + +PS S S P K + +P PA+ PA P
Sbjct: 283 TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPA-QPSGLTKP 341
Query: 330 LRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPP 389
L G++ P P GT K +P P P + +E+ SE+ K L PP
Sbjct: 342 LAQQPGTVKPPVQPPGTTK------PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395
Query: 390 LESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAA---------PGPS-- 438
T + G P+ + + GL SP+ A PGP
Sbjct: 396 GVGK------TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449
Query: 439 -------------------PDSWVPRPGTPQ-SPPSCRAPPPEARGIRAPPL-------- 470
P S +P P P P PPP+ G PP
Sbjct: 450 PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP 509
Query: 471 -PDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGD 529
P P P SP G + P A P+A++ A P +S K P++++
Sbjct: 510 PPQQPGPAKPSPQQPG--STKPPSQQPGSAKPSAQQPSPAKPSAQQSTK---PVSQTGS- 563
Query: 530 LSRSLSPSPLGSSA 543
+ L P + SA
Sbjct: 564 -GKPLQPPTVSPSA 576
Score = 47.4 bits (111), Expect = 6e-05
Identities = 61/241 (25%), Positives = 84/241 (34%), Gaps = 39/241 (16%)
Query: 245 SRREREPEPPAAVDFLEPDSGTCPEVD-----EEGFTVRPDVTQNSTAEPSRFSSS---- 295
S+ E + PP D +P P + + RP + P S S
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844
Query: 296 --DSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSR 353
D EEP+K + P P P R TAG + P + S R
Sbjct: 845 QVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRR 904
Query: 354 ---DAAGKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSS 410
+ P+S P T +E V+ LFG F F+ +S+L T+
Sbjct: 905 FSLNLGSITDAPKSQPTTP--------QETVTGKLFG------FGASIFSQASNLISTAG 950
Query: 411 -PSPFSSSSPENVEDSGLDSPSHAAPGPS--PDSWVPRPGTPQSPPSCRAPPPEARGIRA 467
P P S S P +P AP PS P S P T Q+PP+ P + +A
Sbjct: 951 QPGPHSQSGP--------GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKA 1002
Query: 468 P 468
P
Sbjct: 1003 P 1003
Score = 39.3 bits (90), Expect = 0.015
Identities = 72/270 (26%), Positives = 100/270 (37%), Gaps = 56/270 (20%)
Query: 312 KPAPARAPACSPE---AAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRT 368
KPAP + P+ E A A + ++ P T SS A KP P S ++
Sbjct: 731 KPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP-----TTDLVSSSSATTKPDIPSSKVQS 785
Query: 369 SSCAERLQSEEQVSKNLFGPPL--ESAFDHEDFTGSSSLGFTSSPSPFSSSS-PENVEDS 425
Q+EE+ + PPL +SA + F + SPF S + P DS
Sbjct: 786 -------QAEEKTT-----PPLKTDSAKPSQSFPPTGE-----KVSPFDSKAIPRPASDS 828
Query: 426 GLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWG 485
+ S PGPS +S G Q P + P+ + P PD+ SP P G
Sbjct: 829 KIISH----PGPSSES----KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG 880
Query: 486 LEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSP------- 538
A G +P P +P + +SR+ S L S D +S +P
Sbjct: 881 PRPTA-GQTVPTPQQ--------SPKPQEQSRRFSLNL-GSITDAPKSQPTTPQETVTGK 930
Query: 539 ---LGSSAASTALERPSFLSQTGHGVSRGP 565
G+S S A S Q G GP
Sbjct: 931 LFGFGASIFSQASNLISTAGQPGPHSQSGP 960
Score = 32.3 bits (72), Expect = 1.9
Identities = 35/118 (29%), Positives = 44/118 (37%), Gaps = 16/118 (13%)
Query: 372 AERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPS 431
AER +S +S+ +F P S S+ FTS + F P + SG S S
Sbjct: 2328 AERTKSS--LSETVFDHPPSSVIALPMKEQLSTTYFTSGET-FGQEKPASQLPSGSPSVS 2384
Query: 432 HAAPGPSPD------SWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGP 483
P P +P P PP PPP PP P P P +SP P
Sbjct: 2385 SLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPP-------PPPPPPPLPPPTSPKP 2435
Score = 30.8 bits (68), Expect = 5.5
Identities = 35/133 (26%), Positives = 46/133 (34%), Gaps = 28/133 (21%)
Query: 356 AGKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFS 415
A + ++ A RT S + S ++ P++ FT + G S
Sbjct: 2319 AYRDKKELEAERTKSSLSETVFDHPPS-SVIALPMKEQLSTTYFTSGETFGQEKPASQLP 2377
Query: 416 SSSPEN----------VEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGI 465
S SP S LD + P P P P P P PP PPP
Sbjct: 2378 SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP----PPPPPPPPPP----PPP----- 2424
Query: 466 RAPPL--PDSPQP 476
PPL P SP+P
Sbjct: 2425 --PPLPPPTSPKP 2435
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 49.7 bits (117), Expect = 1e-05
Identities = 73/314 (23%), Positives = 106/314 (33%), Gaps = 66/314 (21%)
Query: 276 TVRPDVTQNSTAEPSRFSSSDSDFDDEEPRK------FYVHIKPAPARAPACSPEAAAAQ 329
T + D+ + + +PS S S P K + +P PA+ PA P
Sbjct: 283 TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPA-QPSGLTKP 341
Query: 330 LRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPP 389
L G++ P P GT K +P P P + +E+ SE+ K L PP
Sbjct: 342 LAQQPGTVKPPVQPPGTTK------PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395
Query: 390 LESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAA---------PGPS-- 438
T + G P+ + + GL SP+ A PGP
Sbjct: 396 GVGK------TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449
Query: 439 -------------------PDSWVPRPGTPQ-SPPSCRAPPPEARGIRAPPL-------- 470
P S +P P P P PPP+ G PP
Sbjct: 450 PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP 509
Query: 471 -PDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGD 529
P P P SP G + P A P+A++ A P +S K P++++
Sbjct: 510 PPQQPGPAKPSPQQPG--STKPPSQQPGSAKPSAQQPSPAKPSAQQSTK---PVSQTGS- 563
Query: 530 LSRSLSPSPLGSSA 543
+ L P + SA
Sbjct: 564 -GKPLQPPTVSPSA 576
Score = 47.4 bits (111), Expect = 6e-05
Identities = 61/241 (25%), Positives = 84/241 (34%), Gaps = 39/241 (16%)
Query: 245 SRREREPEPPAAVDFLEPDSGTCPEVD-----EEGFTVRPDVTQNSTAEPSRFSSS---- 295
S+ E + PP D +P P + + RP + P S S
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844
Query: 296 --DSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSR 353
D EEP+K + P P P R TAG + P + S R
Sbjct: 845 QVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRR 904
Query: 354 ---DAAGKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSS 410
+ P+S P T +E V+ LFG F F+ +S+L T+
Sbjct: 905 FSLNLGSITDAPKSQPTTP--------QETVTGKLFG------FGASIFSQASNLISTAG 950
Query: 411 -PSPFSSSSPENVEDSGLDSPSHAAPGPS--PDSWVPRPGTPQSPPSCRAPPPEARGIRA 467
P P S S P +P AP PS P S P T Q+PP+ P + +A
Sbjct: 951 QPGPHSQSGP--------GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKA 1002
Query: 468 P 468
P
Sbjct: 1003 P 1003
Score = 39.3 bits (90), Expect = 0.015
Identities = 72/270 (26%), Positives = 100/270 (37%), Gaps = 56/270 (20%)
Query: 312 KPAPARAPACSPE---AAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRT 368
KPAP + P+ E A A + ++ P T SS A KP P S ++
Sbjct: 731 KPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP-----TTDLVSSSSATTKPDIPSSKVQS 785
Query: 369 SSCAERLQSEEQVSKNLFGPPL--ESAFDHEDFTGSSSLGFTSSPSPFSSSS-PENVEDS 425
Q+EE+ + PPL +SA + F + SPF S + P DS
Sbjct: 786 -------QAEEKTT-----PPLKTDSAKPSQSFPPTGE-----KVSPFDSKAIPRPASDS 828
Query: 426 GLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWG 485
+ S PGPS +S G Q P + P+ + P PD+ SP P G
Sbjct: 829 KIISH----PGPSSES----KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG 880
Query: 486 LEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSP------- 538
A G +P P +P + +SR+ S L S D +S +P
Sbjct: 881 PRPTA-GQTVPTPQQ--------SPKPQEQSRRFSLNL-GSITDAPKSQPTTPQETVTGK 930
Query: 539 ---LGSSAASTALERPSFLSQTGHGVSRGP 565
G+S S A S Q G GP
Sbjct: 931 LFGFGASIFSQASNLISTAGQPGPHSQSGP 960
Score = 32.3 bits (72), Expect = 1.9
Identities = 35/118 (29%), Positives = 44/118 (37%), Gaps = 16/118 (13%)
Query: 372 AERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPS 431
AER +S +S+ +F P S S+ FTS + F P + SG S S
Sbjct: 2328 AERTKSS--LSETVFDHPPSSVIALPMKEQLSTTYFTSGET-FGQEKPASQLPSGSPSVS 2384
Query: 432 HAAPGPSPD------SWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGP 483
P P +P P PP PPP PP P P P +SP P
Sbjct: 2385 SLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPP-------PPPPPPPLPPPTSPKP 2435
Score = 30.8 bits (68), Expect = 5.5
Identities = 35/133 (26%), Positives = 46/133 (34%), Gaps = 28/133 (21%)
Query: 356 AGKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFS 415
A + ++ A RT S + S ++ P++ FT + G S
Sbjct: 2319 AYRDKKELEAERTKSSLSETVFDHPPS-SVIALPMKEQLSTTYFTSGETFGQEKPASQLP 2377
Query: 416 SSSPEN----------VEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGI 465
S SP S LD + P P P P P P PP PPP
Sbjct: 2378 SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP----PPPPPPPPPP----PPP----- 2424
Query: 466 RAPPL--PDSPQP 476
PPL P SP+P
Sbjct: 2425 --PPLPPPTSPKP 2435
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 49.3 bits (116), Expect = 1e-05
Identities = 54/168 (32%), Positives = 69/168 (41%), Gaps = 34/168 (20%)
Query: 355 AAGKPQRPRSAPR---TSSCAERLQSEEQVSKNLF----GPPLESAFDHEDFT-GSSSLG 406
A+ +P P AP T A L+ EE K L GP + + + S G
Sbjct: 455 ASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGG 514
Query: 407 FTSSPS-PFSSSSPENVEDSGLDSPSHAAPGPSPDSWVPRPGTP---QSPPSCRAPPPEA 462
+P P S SP+ L + APG +P P PG P ++PPS APP
Sbjct: 515 DAPTPGVPTGSPSPD------LAPAAEPAPGAAPPPPPPLPGLPSPQEAPPS--APP--- 563
Query: 463 RGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAP 510
+APPLP SP+P + P P GDL P P P G P
Sbjct: 564 ---QAPPLPGSPEPPPAPPLP--------GDLPPPPPPPPPPPGTDGP 600
Score = 39.7 bits (91), Expect = 0.012
Identities = 30/99 (30%), Positives = 37/99 (37%), Gaps = 14/99 (14%)
Query: 400 TGSSSLGFTSSPSPFSSSSPENVED-SGLDSPSHAAPGPSPDSWVPRPGTPQSPPSC--- 455
TGS S + P ++P GL SP A P P + P PG+P+ PP+
Sbjct: 523 TGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQA-PPLPGSPEPPPAPPLP 581
Query: 456 ---------RAPPPEARGIRAPPLPDSPQPLASSPGPWG 485
PPP G PP P P P P G
Sbjct: 582 GDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALG 620
>gi|223972704 hypothetical protein LOC284418 [Homo sapiens]
Length = 922
Score = 48.5 bits (114), Expect = 3e-05
Identities = 109/455 (23%), Positives = 158/455 (34%), Gaps = 125/455 (27%)
Query: 431 SHAAPGPSPDSWVPRPGT--PQSPPSCRAPPPEARGI-----RAPPLPDSPQPLASSPGP 483
S P SW P PG PQ P+ APP +A + +AP +P Q + P P
Sbjct: 419 SQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAP 478
Query: 484 WGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSA 543
A A P + APP++ P P+ +
Sbjct: 479 -------SRKASAASASPRKASAVPAPPQKTPPPSQKAPSV-----------PTIPQKAV 520
Query: 544 ASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTG 603
+ TA ++ S L P+P SQ ALP T+ TEY A P+ ++ G
Sbjct: 521 SPTAPKKKSLLL---------PAP----SQKALP--TSPTEYQMAL---SPPASRGKLPG 562
Query: 604 ELTMTFPAGI------VRVFSGTPPPPVLSFRLVHTTAIEHF--------------QPNA 643
+ + P GI R SG P PV++ R T +E + +
Sbjct: 563 DFDV-LPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFTVTKKESK 621
Query: 644 DLLFSDPSQSDPET------KDFWLNMAALTE--------------------ALQRQAEQ 677
D+L S + E + W + A L E + A +
Sbjct: 622 DILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRSKELEQRKRWVKAKELAVE 681
Query: 678 NPTASY---YNVVLL-----------RYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYG 723
P+ + ++V L + Q S+ S+P L A Q AT SV
Sbjct: 682 GPSQEHSRPFSVEALTLTKLMITANSKEQPSKSALVSLPSWLLATPQASATSMMASVP-- 739
Query: 724 YRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAA-TWNLEEKRLTWRLPDVSEAGGSGRL 782
RPG Q+ L G+PV VR QP + TW E KR W ++ E
Sbjct: 740 SRPG-----------QLSLLEGKPVV-VREQPESHTWVKEGKR-PW--GEMKEQPWGEMK 784
Query: 783 SASWEPLSGPSTP---SPVAAQFTSEGTTLSGVDL 814
W+P P P P +A EG + + + L
Sbjct: 785 EPPWDPKGPPKVPFRSKPTSASLKREGISQAPIPL 819
>gi|41281612 zinc finger protein 828 [Homo sapiens]
Length = 812
Score = 48.5 bits (114), Expect = 3e-05
Identities = 82/315 (26%), Positives = 108/315 (34%), Gaps = 65/315 (20%)
Query: 241 LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD 300
+P LS ++ + + +P T E + G V P++ T PS S +
Sbjct: 127 IPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPEL---QTPLPSPEPSKPASVS 183
Query: 301 DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ 360
EP K V + + AP SPE P P S+ KPQ
Sbjct: 184 SPEPPKS-VPVCESQKLAPVPSPEPQKPA----------PVSPESVKATLSNP----KPQ 228
Query: 361 RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSS--- 417
+ P T GPP S+ S +SP P+ S
Sbjct: 229 KQSHFPET-----------------LGPPSASS--------PESPVLAASPEPWGPSPAA 263
Query: 418 SPENVEDSGLDSPSHAAPGPS--PDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQ 475
SPE+ + + SP P PS P+ W P P SP R P + G P P SP+
Sbjct: 264 SPESRKSARTTSPEPRKPSPSESPEPWKPFPAV--SPEPRRPAPAVSPGSWKPGPPGSPR 321
Query: 476 PLASSP----GPWGLEALAGGDLMPAPADPTAREGLAAP-PRRLRSRKVSCPLTRSNGDL 530
P S+P GPW PA P+ G P P P S
Sbjct: 322 PWKSNPSASSGPW----------KPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWK 371
Query: 531 SRSLSPSPLGSSAAS 545
S S+SPS S AS
Sbjct: 372 SSSVSPSSWKSPPAS 386
Score = 41.6 bits (96), Expect = 0.003
Identities = 70/292 (23%), Positives = 103/292 (35%), Gaps = 42/292 (14%)
Query: 200 RKFAESKGTGREKPGPLDFEAYSAAALQ-EAMKRLRGAKAFRLPGLSRREREPEPPAAVD 258
+K A +KP P+ E+ A + K+ + P S E P A+ +
Sbjct: 197 QKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPE-SPVLAASPE 255
Query: 259 FLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPAPAR- 317
P PE + T P EP + S S+S EP K + + P P R
Sbjct: 256 PWGPSPAASPESRKSARTTSP--------EPRKPSPSESP----EPWKPFPAVSPEPRRP 303
Query: 318 APACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCAERLQS 377
APA SP + PGP G+ + S +A + P S +
Sbjct: 304 APAVSPGS-------------WKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKP 350
Query: 378 EEQVSKNLFGPP---LESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAA 434
VS + P +++ + SS +SP + S PE A
Sbjct: 351 IPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPE---------LRKTA 401
Query: 435 PGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGL 486
P SP+ W P P SP + PP + IR+P + + SP W L
Sbjct: 402 PTLSPEHWKAVP--PVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKL 451
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,162,309
Number of Sequences: 37866
Number of extensions: 2366266
Number of successful extensions: 19607
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 233
Number of HSP's successfully gapped in prelim test: 1485
Number of HSP's that attempted gapping in prelim test: 12267
Number of HSP's gapped (non-prelim): 5916
length of query: 839
length of database: 18,247,518
effective HSP length: 111
effective length of query: 728
effective length of database: 14,044,392
effective search space: 10224317376
effective search space used: 10224317376
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.