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Search of human proteins with 237858675
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|237858675 neurofascin isoform 1 precursor [Homo sapiens]
(1240 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|237858675 neurofascin isoform 1 precursor [Homo sapiens] 2535 0.0
gi|237858677 neurofascin isoform 2 precursor [Homo sapiens] 1684 0.0
gi|237858679 neurofascin isoform 3 precursor [Homo sapiens] 1645 0.0
gi|89903008 neurofascin isoform 4 precursor [Homo sapiens] 1645 0.0
gi|237858680 neurofascin isoform 5 precursor [Homo sapiens] 1255 0.0
gi|237858682 neurofascin isoform 6 precursor [Homo sapiens] 1237 0.0
gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 1096 0.0
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 1047 0.0
gi|27894376 cell adhesion molecule with homology to L1CAM precur... 709 0.0
gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo... 624 e-178
gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo ... 620 e-177
gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo s... 620 e-177
gi|4827022 contactin 2 precursor [Homo sapiens] 348 2e-95
gi|7657359 contactin 5 isoform long [Homo sapiens] 346 7e-95
gi|28373129 contactin 5 isoform short [Homo sapiens] 346 7e-95
gi|28373122 contactin 4 isoform a precursor [Homo sapiens] 339 8e-93
gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens] 337 4e-92
gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens] 337 4e-92
gi|75709184 contactin 3 [Homo sapiens] 330 5e-90
gi|7657361 contactin 6 [Homo sapiens] 298 3e-80
gi|28373126 contactin 4 isoform c precursor [Homo sapiens] 238 3e-62
gi|119220552 sidekick 1 [Homo sapiens] 225 2e-58
gi|222352127 sidekick 2 [Homo sapiens] 196 2e-49
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 194 3e-49
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 192 1e-48
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 184 3e-46
gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ... 184 6e-46
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 181 3e-45
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 180 7e-45
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 180 7e-45
>gi|237858675 neurofascin isoform 1 precursor [Homo sapiens]
Length = 1240
Score = 2535 bits (6570), Expect = 0.0
Identities = 1240/1240 (100%), Positives = 1240/1240 (100%)
Query: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNIL 60
MARQPPPPWVHAAFLLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNIL
Sbjct: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNIL 60
Query: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA
Sbjct: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
Query: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM 180
RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM
Sbjct: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM 180
Query: 181 EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVA 240
EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVA
Sbjct: 181 EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVA 240
Query: 241 ERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKA 300
ERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKA
Sbjct: 241 ERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKA 300
Query: 301 LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRA 360
LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRA
Sbjct: 301 LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRA 360
Query: 361 NGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLAN 420
NGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLAN
Sbjct: 361 NGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLAN 420
Query: 421 AFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHV 480
AFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHV
Sbjct: 421 AFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHV 480
Query: 481 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 540
YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ
Sbjct: 481 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 540
Query: 541 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQ 600
LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQ
Sbjct: 541 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQ 600
Query: 601 DLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITD 660
DLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITD
Sbjct: 601 DLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITD 660
Query: 661 YVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERY 720
YVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERY
Sbjct: 661 YVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERY 720
Query: 721 RTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVT 780
RTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVT
Sbjct: 721 RTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVT 780
Query: 781 VWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLET 840
VWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLET
Sbjct: 781 VWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLET 840
Query: 841 INLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTL 900
INLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTL
Sbjct: 841 INLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTL 900
Query: 901 SARTQVGSGEAVTEESPAPPNEATPTAAPPTLPPTTVGATGAVSSTDATAIAATTEATTV 960
SARTQVGSGEAVTEESPAPPNEATPTAAPPTLPPTTVGATGAVSSTDATAIAATTEATTV
Sbjct: 901 SARTQVGSGEAVTEESPAPPNEATPTAAPPTLPPTTVGATGAVSSTDATAIAATTEATTV 960
Query: 961 PIIPTVAPTTIATTTTVATTTTTTAAATTTTESPPTTTSGTKIHESAPDEQSIWNVTVLP 1020
PIIPTVAPTTIATTTTVATTTTTTAAATTTTESPPTTTSGTKIHESAPDEQSIWNVTVLP
Sbjct: 961 PIIPTVAPTTIATTTTVATTTTTTAAATTTTESPPTTTSGTKIHESAPDEQSIWNVTVLP 1020
Query: 1021 NSKWANITWKHNFGPGTDFVVEYIDSNHTKKTVPVKAQAQPIQLTDLYPGMTYTLRVYSR 1080
NSKWANITWKHNFGPGTDFVVEYIDSNHTKKTVPVKAQAQPIQLTDLYPGMTYTLRVYSR
Sbjct: 1021 NSKWANITWKHNFGPGTDFVVEYIDSNHTKKTVPVKAQAQPIQLTDLYPGMTYTLRVYSR 1080
Query: 1081 DNEGISSTVITFMTSTAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYP 1140
DNEGISSTVITFMTSTAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYP
Sbjct: 1081 DNEGISSTVITFMTSTAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYP 1140
Query: 1141 VREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDDSLVDYGEGGEG 1200
VREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDDSLVDYGEGGEG
Sbjct: 1141 VREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDDSLVDYGEGGEG 1200
Query: 1201 QFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA 1240
QFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA
Sbjct: 1201 QFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA 1240
>gi|237858677 neurofascin isoform 2 precursor [Homo sapiens]
Length = 1189
Score = 1684 bits (4361), Expect = 0.0
Identities = 844/953 (88%), Positives = 863/953 (90%), Gaps = 34/953 (3%)
Query: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNIL 60
MARQPPPPWVHAAFLLCLLSLGGAIEIPMD LTQPPTITKQSAKDHIVDPRDNIL
Sbjct: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMD------LTQPPTITKQSAKDHIVDPRDNIL 54
Query: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA
Sbjct: 55 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 114
Query: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM 180
RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM
Sbjct: 115 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM 174
Query: 181 EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTT---- 236
EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLT
Sbjct: 175 EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYN 234
Query: 237 -------------RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK 283
RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK
Sbjct: 235 DSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK 294
Query: 284 GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 343
GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP
Sbjct: 295 GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 354
Query: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 403
KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR
Sbjct: 355 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 414
Query: 404 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 463
AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR
Sbjct: 415 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 474
Query: 464 WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTR 523
WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTR
Sbjct: 475 WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTR 534
Query: 524 IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVA 583
IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVA
Sbjct: 535 IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVA 594
Query: 584 ERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERS 643
ERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERS
Sbjct: 595 ERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERS 654
Query: 644 VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVI 703
VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVI
Sbjct: 655 VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVI 714
Query: 704 AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY 763
AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY
Sbjct: 715 AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY 774
Query: 764 IVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGED 823
IVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGED
Sbjct: 775 IVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGED 834
Query: 824 LP-SAPRRFRVRQPNLETINLEWD--HPEHPNGIMIGYTLKY-----VAFNGTKVGKQIV 875
P +AP +VR N I+L+W+ + + G + Y Y + N K+
Sbjct: 835 YPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQ 894
Query: 876 ENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSG-EAVTEESPAPPNEATPTA 927
+F ++ + V R P S Y+ + G G + T+E P E P+A
Sbjct: 895 ASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP--EGVPSA 945
Score = 302 bits (773), Expect = 1e-81
Identities = 162/236 (68%), Positives = 176/236 (74%), Gaps = 15/236 (6%)
Query: 1020 PNSKWANITWKHNFGPG---TDFVVEYIDSNHTKKTVPVKAQAQP------IQLTDLYPG 1070
PN + N+ W H P + ++Y+ N TK + P +Q TD
Sbjct: 954 PNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSR 1013
Query: 1071 MTYTLRVYSRDNEGISSTVIT------FMTSTAYTNNQADIATQGWFIGLMCAIALLVLI 1124
+TL ++ G + T + + AYTNNQADIATQGWFIGLMCAIALLVLI
Sbjct: 1014 YRFTLSARTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALLVLI 1073
Query: 1125 LLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQ 1184
LLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQ
Sbjct: 1074 LLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQ 1133
Query: 1185 QESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA 1240
QESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA
Sbjct: 1134 QESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA 1189
Score = 301 bits (771), Expect = 3e-81
Identities = 295/966 (30%), Positives = 434/966 (44%), Gaps = 115/966 (11%)
Query: 33 IQNELTQPPTITKQSAKDHIVDPRDNILIECEAK-GNPAPSFHWTRNSRFFNIAKDPRVS 91
I+ ++++ P K++ +V + ++C G P+P W +S I +D RVS
Sbjct: 126 IRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSS-MEPITQDKRVS 184
Query: 92 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALS--NRIRLQV------------- 136
+ +G L + S ++ + +Y C AR F + N L+V
Sbjct: 185 -QGHNGDL---YFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRN 240
Query: 137 -------------SKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPI 183
+ S ++P+ +V G L L+C G+P+P I W + +
Sbjct: 241 HPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGD-L 298
Query: 184 TQDKRVSQGHNGDLYFSNVMLQDMQTDYSC---NARFHFTHTIQQKNPFTLKVLTTRGVA 240
DK + N L +NV +D +Y C N HTI +
Sbjct: 299 PSDKAKFENFNKALRITNVSEED-SGEYFCLASNKMGSIRHTI----------------S 341
Query: 241 ERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL----PSDKAKFEN 296
R + Y + ++ G D L C A+G P P + W G L P+ +
Sbjct: 342 VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG 401
Query: 297 FNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAP--GEDG 354
R T +S Y C SN+ G + V V P + P+N ++
Sbjct: 402 DTIIFRDTQISSR--AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRT 459
Query: 355 RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEH 414
RL C G+P PT++W NG+ N + G I + + + +Y C +N
Sbjct: 460 RLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEI-KMIRKEDQGIYTCVATNIL 518
Query: 415 GYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIP--TLRWFKNGQGSN 472
G + V D P +Q+ R +L+C P T+ W K+ +
Sbjct: 519 GKAENQVRLEVKDPTRIYRMPEDQVAR--RGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 576
Query: 473 LDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNIL----GKAENQVRLEVKDPT-RIYRM 527
+ GN E+ SL I + + DQG YTCVA+ L KA V + PT R+ +
Sbjct: 577 I--GNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAAL 634
Query: 528 PEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDD---EPL--YIGNRMKKEDDSLT--IF 580
P+ + R LE + S++LT W+ D P+ Y+ ++ E+D ++
Sbjct: 635 PKGRPDRPR---DLELTDLAERSVRLT--WIPGDANNSPITDYV---VQFEEDQFQPGVW 686
Query: 581 GVAERDQGSYTCVASTELDQDLAKAYLTVLADQ------ATPTNRLAALPKGRPDRPRDL 634
+ GS A L + + + ++ + P+ R P D+
Sbjct: 687 HDHSKYPGSVNS-AVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDV 745
Query: 635 ELTDLAERSVRLTWIPGDANNS--PITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRL 692
+ + ++ +TW P +A ++ P Y+V++ + + W++ + + GS V +
Sbjct: 746 KGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREA-WNNVTVW-GS-RYVVGQT 802
Query: 693 SPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNMEITWTPM 751
YV Y+ RV A N+ G P SG P + P +VK + + W +
Sbjct: 803 PVYVPYEIRVQAENDFGKGPE--PESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRV 860
Query: 752 NATSAFGPNLRYIVKWRRRET--REAW-----NNVTVWGSRY--VVGQTPVYVPYEIRVQ 802
+ + G Y + R + + W + G R VV + Y Y++ +
Sbjct: 861 YSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMV 920
Query: 803 AENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKY 862
N G GP E+ + E +PSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKY
Sbjct: 921 VVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKY 980
Query: 863 VAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNE 922
VAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNE
Sbjct: 981 VAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNE 1040
Query: 923 ATPTAA 928
ATPTAA
Sbjct: 1041 ATPTAA 1046
>gi|237858679 neurofascin isoform 3 precursor [Homo sapiens]
Length = 1174
Score = 1645 bits (4260), Expect = 0.0
Identities = 829/953 (86%), Positives = 848/953 (88%), Gaps = 49/953 (5%)
Query: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNIL 60
MARQPPPPWVHAAFLLCLLSLGGAIEIPMD LTQPPTITKQSAKDHIVDPRDNIL
Sbjct: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMD------LTQPPTITKQSAKDHIVDPRDNIL 54
Query: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA
Sbjct: 55 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 114
Query: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM 180
RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM
Sbjct: 115 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM 174
Query: 181 EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTT---- 236
EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLT
Sbjct: 175 EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYN 234
Query: 237 -------------RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK 283
RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK
Sbjct: 235 DSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK 294
Query: 284 GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 343
GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP
Sbjct: 295 GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 354
Query: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 403
KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR
Sbjct: 355 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 414
Query: 404 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 463
AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR
Sbjct: 415 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 474
Query: 464 WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTR 523
WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTR
Sbjct: 475 WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTR 534
Query: 524 IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVA 583
IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVA
Sbjct: 535 IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVA 594
Query: 584 ERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERS 643
ERDQGSYTCVASTELDQDLAKAYLTVL GRPDRPRDLELTDLAERS
Sbjct: 595 ERDQGSYTCVASTELDQDLAKAYLTVL---------------GRPDRPRDLELTDLAERS 639
Query: 644 VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVI 703
VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVI
Sbjct: 640 VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVI 699
Query: 704 AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY 763
AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY
Sbjct: 700 AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY 759
Query: 764 IVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGED 823
IVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGED
Sbjct: 760 IVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGED 819
Query: 824 LP-SAPRRFRVRQPNLETINLEWD--HPEHPNGIMIGYTLKY-----VAFNGTKVGKQIV 875
P +AP +VR N I+L+W+ + + G + Y Y + N K+
Sbjct: 820 YPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQ 879
Query: 876 ENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSG-EAVTEESPAPPNEATPTA 927
+F ++ + V R P S Y+ + G G + T+E P E P+A
Sbjct: 880 ASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP--EGVPSA 930
Score = 302 bits (773), Expect = 1e-81
Identities = 162/236 (68%), Positives = 176/236 (74%), Gaps = 15/236 (6%)
Query: 1020 PNSKWANITWKHNFGPG---TDFVVEYIDSNHTKKTVPVKAQAQP------IQLTDLYPG 1070
PN + N+ W H P + ++Y+ N TK + P +Q TD
Sbjct: 939 PNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSR 998
Query: 1071 MTYTLRVYSRDNEGISSTVIT------FMTSTAYTNNQADIATQGWFIGLMCAIALLVLI 1124
+TL ++ G + T + + AYTNNQADIATQGWFIGLMCAIALLVLI
Sbjct: 999 YRFTLSARTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALLVLI 1058
Query: 1125 LLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQ 1184
LLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQ
Sbjct: 1059 LLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQ 1118
Query: 1185 QESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA 1240
QESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA
Sbjct: 1119 QESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA 1174
Score = 300 bits (769), Expect = 4e-81
Identities = 285/952 (29%), Positives = 421/952 (44%), Gaps = 102/952 (10%)
Query: 33 IQNELTQPPTITKQSAKDHIVDPRDNILIECEAK-GNPAPSFHWTRNSRFFNIAKDPRVS 91
I+ ++++ P K++ +V + ++C G P+P W +S I +D RVS
Sbjct: 126 IRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSS-MEPITQDKRVS 184
Query: 92 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALS--NRIRLQV------------- 136
+ +G L + S ++ + +Y C AR F + N L+V
Sbjct: 185 -QGHNGDL---YFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRN 240
Query: 137 -------------SKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPI 183
+ S ++P+ +V G L L+C G+P+P I W + +
Sbjct: 241 HPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGD-L 298
Query: 184 TQDKRVSQGHNGDLYFSNVMLQDMQTDYSC---NARFHFTHTIQQKNPFTLKVLTTRGVA 240
DK + N L +NV +D +Y C N HTI +
Sbjct: 299 PSDKAKFENFNKALRITNVSEED-SGEYFCLASNKMGSIRHTI----------------S 341
Query: 241 ERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL----PSDKAKFEN 296
R + Y + ++ G D L C A+G P P + W G L P+ +
Sbjct: 342 VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG 401
Query: 297 FNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAP--GEDG 354
R T +S Y C SN+ G + V V P + P+N ++
Sbjct: 402 DTIIFRDTQISSR--AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRT 459
Query: 355 RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEH 414
RL C G+P PT++W NG+ N + G I + + + +Y C +N
Sbjct: 460 RLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEI-KMIRKEDQGIYTCVATNIL 518
Query: 415 GYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIP--TLRWFKNGQGSN 472
G + V D P +Q+ R +L+C P T+ W K+ +
Sbjct: 519 GKAENQVRLEVKDPTRIYRMPEDQVAR--RGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 576
Query: 473 LDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD-PTRIYRMPEDQ 531
+ GN E+ SL I + + DQG YTCVA+ L + + L V P R +
Sbjct: 577 I--GNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRDLELTD 634
Query: 532 VARRGTTVQ-LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLT--IFGVAERDQG 588
+A R + + + P V + +D + + K S+ + ++
Sbjct: 635 LAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNY 694
Query: 589 SYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTW 648
+ +A E+ + + P+ R P D++ + ++ +TW
Sbjct: 695 QFRVIAINEVGS----------SHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITW 744
Query: 649 IPGDANNS--PITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAIN 706
P +A ++ P Y+V++ + + W++ + + GS V + YV Y+ RV A N
Sbjct: 745 TPMNATSAFGPNLRYIVKWRRRETREA-WNNVTVW-GS-RYVVGQTPVYVPYEIRVQAEN 801
Query: 707 EVGSSHPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIV 765
+ G P SG P + P +VK + + W + + + G Y
Sbjct: 802 DFGKGPE--PESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRA 859
Query: 766 KWRRRET--REAW-----NNVTVWGSRY--VVGQTPVYVPYEIRVQAENDFGKGPEPESV 816
+ R + + W + G R VV + Y Y++ + N G GP E+
Sbjct: 860 YYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETK 919
Query: 817 IGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVE 876
+ E +PSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVE
Sbjct: 920 EFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVE 979
Query: 877 NFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAA 928
NFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAA
Sbjct: 980 NFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAA 1031
>gi|89903008 neurofascin isoform 4 precursor [Homo sapiens]
Length = 1169
Score = 1645 bits (4260), Expect = 0.0
Identities = 829/953 (86%), Positives = 848/953 (88%), Gaps = 49/953 (5%)
Query: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNIL 60
MARQPPPPWVHAAFLLCLLSLGGAIEIPMD LTQPPTITKQSAKDHIVDPRDNIL
Sbjct: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMD------LTQPPTITKQSAKDHIVDPRDNIL 54
Query: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA
Sbjct: 55 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 114
Query: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM 180
RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM
Sbjct: 115 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM 174
Query: 181 EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTT---- 236
EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLT
Sbjct: 175 EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYN 234
Query: 237 -------------RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK 283
RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK
Sbjct: 235 DSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK 294
Query: 284 GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 343
GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP
Sbjct: 295 GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 354
Query: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 403
KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR
Sbjct: 355 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 414
Query: 404 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 463
AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR
Sbjct: 415 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 474
Query: 464 WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTR 523
WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTR
Sbjct: 475 WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTR 534
Query: 524 IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVA 583
IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVA
Sbjct: 535 IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVA 594
Query: 584 ERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERS 643
ERDQGSYTCVASTELDQDLAKAYLTVL GRPDRPRDLELTDLAERS
Sbjct: 595 ERDQGSYTCVASTELDQDLAKAYLTVL---------------GRPDRPRDLELTDLAERS 639
Query: 644 VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVI 703
VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVI
Sbjct: 640 VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVI 699
Query: 704 AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY 763
AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY
Sbjct: 700 AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY 759
Query: 764 IVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGED 823
IVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGED
Sbjct: 760 IVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGED 819
Query: 824 LP-SAPRRFRVRQPNLETINLEWD--HPEHPNGIMIGYTLKY-----VAFNGTKVGKQIV 875
P +AP +VR N I+L+W+ + + G + Y Y + N K+
Sbjct: 820 YPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQ 879
Query: 876 ENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSG-EAVTEESPAPPNEATPTA 927
+F ++ + V R P S Y+ + G G + T+E P E P+A
Sbjct: 880 ASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP--EGVPSA 930
Score = 303 bits (776), Expect = 7e-82
Identities = 162/231 (70%), Positives = 176/231 (76%), Gaps = 10/231 (4%)
Query: 1020 PNSKWANITWKHNFGPG---TDFVVEYIDSNHTKKTVPVKAQAQP------IQLTDLYPG 1070
PN + N+ W H P + ++Y+ N TK + P +Q TD
Sbjct: 939 PNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSR 998
Query: 1071 MTYTLRVYSRDNEGISSTVIT-FMTSTAYTNNQADIATQGWFIGLMCAIALLVLILLIVC 1129
+TL ++ G + T + + AYTNNQADIATQGWFIGLMCAIALLVLILLIVC
Sbjct: 999 YRFTLSARTQVGSGEAVTEESPAPPNEAYTNNQADIATQGWFIGLMCAIALLVLILLIVC 1058
Query: 1130 FIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDD 1189
FIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDD
Sbjct: 1059 FIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDD 1118
Query: 1190 SLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA 1240
SLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA
Sbjct: 1119 SLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA 1169
Score = 291 bits (744), Expect = 3e-78
Identities = 280/947 (29%), Positives = 416/947 (43%), Gaps = 102/947 (10%)
Query: 33 IQNELTQPPTITKQSAKDHIVDPRDNILIECEAK-GNPAPSFHWTRNSRFFNIAKDPRVS 91
I+ ++++ P K++ +V + ++C G P+P W +S I +D RVS
Sbjct: 126 IRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSS-MEPITQDKRVS 184
Query: 92 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALS--NRIRLQV------------- 136
+ +G L + S ++ + +Y C AR F + N L+V
Sbjct: 185 -QGHNGDL---YFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRN 240
Query: 137 -------------SKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPI 183
+ S ++P+ +V G L L+C G+P+P I W + +
Sbjct: 241 HPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGD-L 298
Query: 184 TQDKRVSQGHNGDLYFSNVMLQDMQTDYSC---NARFHFTHTIQQKNPFTLKVLTTRGVA 240
DK + N L +NV +D +Y C N HTI +
Sbjct: 299 PSDKAKFENFNKALRITNVSEED-SGEYFCLASNKMGSIRHTI----------------S 341
Query: 241 ERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL----PSDKAKFEN 296
R + Y + ++ G D L C A+G P P + W G L P+ +
Sbjct: 342 VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG 401
Query: 297 FNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAP--GEDG 354
R T +S Y C SN+ G + V V P + P+N ++
Sbjct: 402 DTIIFRDTQISSR--AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRT 459
Query: 355 RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEH 414
RL C G+P PT++W NG+ N + G I + + + +Y C +N
Sbjct: 460 RLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEI-KMIRKEDQGIYTCVATNIL 518
Query: 415 GYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIP--TLRWFKNGQGSN 472
G + V D P +Q+ R +L+C P T+ W K+ +
Sbjct: 519 GKAENQVRLEVKDPTRIYRMPEDQVAR--RGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 576
Query: 473 LDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD-PTRIYRMPEDQ 531
+ GN E+ SL I + + DQG YTCVA+ L + + L V P R +
Sbjct: 577 I--GNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRDLELTD 634
Query: 532 VARRGTTVQ-LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLT--IFGVAERDQG 588
+A R + + + P V + +D + + K S+ + ++
Sbjct: 635 LAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNY 694
Query: 589 SYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTW 648
+ +A E+ + + P+ R P D++ + ++ +TW
Sbjct: 695 QFRVIAINEVGS----------SHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITW 744
Query: 649 IPGDANNS--PITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAIN 706
P +A ++ P Y+V++ + + W++ + + GS V + YV Y+ RV A N
Sbjct: 745 TPMNATSAFGPNLRYIVKWRRRETREA-WNNVTVW-GS-RYVVGQTPVYVPYEIRVQAEN 801
Query: 707 EVGSSHPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIV 765
+ G P SG P + P +VK + + W + + + G Y
Sbjct: 802 DFGKGPE--PESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRA 859
Query: 766 KWRRRET--REAW-----NNVTVWGSRY--VVGQTPVYVPYEIRVQAENDFGKGPEPESV 816
+ R + + W + G R VV + Y Y++ + N G GP E+
Sbjct: 860 YYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETK 919
Query: 817 IGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVE 876
+ E +PSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVE
Sbjct: 920 EFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVE 979
Query: 877 NFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEA 923
NFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEA
Sbjct: 980 NFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEA 1026
>gi|237858680 neurofascin isoform 5 precursor [Homo sapiens]
Length = 619
Score = 1255 bits (3248), Expect = 0.0
Identities = 610/612 (99%), Positives = 611/612 (99%)
Query: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNIL 60
MARQPPPPWVHAAFLLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNIL
Sbjct: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNIL 60
Query: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA
Sbjct: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
Query: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM 180
RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM
Sbjct: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM 180
Query: 181 EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVA 240
EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVA
Sbjct: 181 EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVA 240
Query: 241 ERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKA 300
ERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKA
Sbjct: 241 ERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKA 300
Query: 301 LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRA 360
LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRA
Sbjct: 301 LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRA 360
Query: 361 NGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLAN 420
NGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLAN
Sbjct: 361 NGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLAN 420
Query: 421 AFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHV 480
AFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHV
Sbjct: 421 AFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHV 480
Query: 481 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 540
YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ
Sbjct: 481 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 540
Query: 541 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQ 600
LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQ
Sbjct: 541 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQ 600
Query: 601 DLAKAYLTVLAD 612
DLAKAYLTVL +
Sbjct: 601 DLAKAYLTVLGN 612
>gi|237858682 neurofascin isoform 6 precursor [Homo sapiens]
Length = 613
Score = 1237 bits (3200), Expect = 0.0
Identities = 604/612 (98%), Positives = 605/612 (98%), Gaps = 6/612 (0%)
Query: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNIL 60
MARQPPPPWVHAAFLLCLLSLGGAIEIPMD LTQPPTITKQSAKDHIVDPRDNIL
Sbjct: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMD------LTQPPTITKQSAKDHIVDPRDNIL 54
Query: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA
Sbjct: 55 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 114
Query: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM 180
RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM
Sbjct: 115 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM 174
Query: 181 EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVA 240
EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVA
Sbjct: 175 EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVA 234
Query: 241 ERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKA 300
ERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKA
Sbjct: 235 ERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKA 294
Query: 301 LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRA 360
LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRA
Sbjct: 295 LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRA 354
Query: 361 NGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLAN 420
NGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLAN
Sbjct: 355 NGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLAN 414
Query: 421 AFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHV 480
AFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHV
Sbjct: 415 AFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHV 474
Query: 481 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 540
YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ
Sbjct: 475 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 534
Query: 541 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQ 600
LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQ
Sbjct: 535 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQ 594
Query: 601 DLAKAYLTVLAD 612
DLAKAYLTVL +
Sbjct: 595 DLAKAYLTVLGN 606
>gi|81158226 neuronal cell adhesion molecule isoform A precursor [Homo
sapiens]
Length = 1304
Score = 1096 bits (2834), Expect = 0.0
Identities = 603/1301 (46%), Positives = 806/1301 (61%), Gaps = 95/1301 (7%)
Query: 15 LLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFH 74
+L L + A+E+P+DP + +L QPPTIT+QS KD+I+DPR+NI+I+CEAKG P PSF
Sbjct: 20 ILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFS 79
Query: 75 WTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRL 134
WTRN F+I KDP V+M+ +GTL+I+ S G+ E YEG YQC ARN+ G A+SN I +
Sbjct: 80 WTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 139
Query: 135 QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHN 194
+ S+SPLW KE L+P+ +Q G L L C PP GLP P+IFWM +S + + Q +RVSQG N
Sbjct: 140 RPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLN 199
Query: 195 GDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTT------------------ 236
GDLYFSNV+ +D + DY C ARF+ T TIQQK P ++KV++
Sbjct: 200 GDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYG 259
Query: 237 -RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFE 295
+ ER P+F+ P+G AS++ LRG L LECIA G+PTP I W K+ G LP ++ ++
Sbjct: 260 AKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK 319
Query: 296 NFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGR 355
NF K L+I +VSE DSG Y C+A N +G+I HTISVRVKAAPYW+ P+NL+L+PGEDG
Sbjct: 320 NFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT 379
Query: 356 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 415
L+CRANGNPKP + W+ NG P++ AP +P+R++ GDTIIF + Q S AVYQCN SNE+G
Sbjct: 380 LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYG 439
Query: 416 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG 475
YLLANAFV+VL PPR+L+P N L +VI LDC FFGSP+PT+ WFK +GS L
Sbjct: 440 YLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE 499
Query: 476 GNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARR 535
Y ++ENG+LEI + +K+ G YTCVA N LG A+N+V LE+KDPT I + PE V +R
Sbjct: 500 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 559
Query: 536 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVAS 595
G+ V EC+VKHD +L LTV WLKD+ L R + D L + V++ D G+YTCVA+
Sbjct: 560 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVAN 619
Query: 596 TELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANN 655
T LD A A L+V+A TP A P+ P DLELTD ++SV+L+W PGD NN
Sbjct: 620 TTLDSVSASAVLSVVAPTPTP-----APVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNN 674
Query: 656 SPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSL 715
SPIT +++++E+ +PG+WH ++ G+ +A L+LSPYVNY FRV+A+N +G S PS
Sbjct: 675 SPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSE 734
Query: 716 PSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREA 775
SE+Y T + P+ NP V+G G+ +N+ ITW P+N + GP L+Y V WR+++ +
Sbjct: 735 ASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDE 794
Query: 776 WNNVTVWG-SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPS-APRRFRV 833
W +V V S+Y+V TP +VPY I+VQA ND G PEP V+G+SGEDLP AP RV
Sbjct: 795 WTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRV 854
Query: 834 RQPNLETINLEWDHP--EHPNGIMIGYTLKY-VAFNGTKVGKQIVE----NFSPNQTKFT 886
N + WD + G + GY + Y + +K ++ +E F ++T
Sbjct: 855 NVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGM 914
Query: 887 VQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEA--TPTAAP----------PTL-- 932
+ +P S Y TL+ R G G E PA P+ TP P PTL
Sbjct: 915 LPGLEPFSHY--TLNVRVVNGKG-----EGPASPDRVFNTPEGVPSAPSSLKIVNPTLDS 967
Query: 933 ------PPTTVGATGAVSSTDATAIAATTEATTVPIIPTVAPTT---------------- 970
PP+ + I +T E P++ P
Sbjct: 968 LTLEWDPPSHPNGILTEYTLKYQPINSTHELG--PLVDLKIPANKTRWTLKNLNFSTRYK 1025
Query: 971 ---IATTTTVATTTTTTAAATTTTES---PPTTTSGTKIHESAPDEQSIWNVTVLPNSKW 1024
A T+ + + T A TT E+ PP +G K+ P I N+T +
Sbjct: 1026 FYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAG-KVQAVNP---RISNLTAAAAETY 1081
Query: 1025 ANITWKHNFGPGTDFVVEY--IDSNHTKKTVPVKAQAQPIQLTDLYPGMTYTLRVYSRDN 1082
ANI+W++ +F VEY S + V L L PG Y +RV + +
Sbjct: 1082 ANISWEYEGPEHVNFYVEYGVAGSKEEWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAVGD 1141
Query: 1083 EGISSTVITFMTSTAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVR 1142
G S+ F T A + Q DIATQGWFIGLMCA+ALL+LILLIVCFI+R++GGKYPV+
Sbjct: 1142 SGFVSSEDVFETGPAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVK 1201
Query: 1143 EKKDVPLGPE--DPKEEDGSF-DYSD-EDNKPL-QGSQTSLDGTIKQQESDDSLVDYGEG 1197
EK+D PE KE+DG+F +YSD ED+KPL +GS+T D T+K+++SDDSLVDYGEG
Sbjct: 1202 EKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEG 1261
Query: 1198 GEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYS 1238
GQFNEDGSFIGQY+ KK+KE EGNESSEA SPVNA+ S
Sbjct: 1262 VNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNS 1302
>gi|81158224 neuronal cell adhesion molecule isoform B precursor [Homo
sapiens]
Length = 1183
Score = 1047 bits (2707), Expect = 0.0
Identities = 576/1262 (45%), Positives = 771/1262 (61%), Gaps = 138/1262 (10%)
Query: 15 LLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFH 74
+L L + A+E+P+D L QPPTIT+QS KD+I+DPR+NI+I+CEAKG P PSF
Sbjct: 20 ILFLCQMISALEVPLD------LVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFS 73
Query: 75 WTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRL 134
WTRN F+I KDP V+M+ +GTL+I+ S G+ E YEG YQC ARN+ G A+SN I +
Sbjct: 74 WTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 133
Query: 135 QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHN 194
+ S+SPLW KE L+P+ +Q G L L C PP GLP P+IFWM +S + + Q +RVSQG N
Sbjct: 134 RPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLN 193
Query: 195 GDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTT------------------ 236
GDLYFSNV+ +D + DY C ARF+ T TIQQK P ++KV++
Sbjct: 194 GDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYG 253
Query: 237 -RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFE 295
+ ER P+F+ P+G AS++ LRG L LECIA G+PTP I W K+ G LP ++ ++
Sbjct: 254 AKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK 313
Query: 296 NFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGR 355
NF K L+I +VSE DSG Y C+A N +G+I HTISVRVKAAPYW+ P+NL+L+PGEDG
Sbjct: 314 NFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT 373
Query: 356 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 415
L+CRANGNPKP + W+ NG P++ AP +P+R++ GDTIIF + Q S AVYQCN SNE+G
Sbjct: 374 LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYG 433
Query: 416 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG 475
YLLANAFV+VL PPR+L+P N L +VI LDC FFGSP+PT+ WFK +GS L
Sbjct: 434 YLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE 493
Query: 476 GNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARR 535
Y ++ENG+LEI + +K+ G YTCVA N LG A+N+V LE+KDPT I + PE V +R
Sbjct: 494 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 553
Query: 536 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVAS 595
G+ V EC+VKHD +L LTV WLKD+ L R + D L + V++ D G+YTCVA+
Sbjct: 554 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVAN 613
Query: 596 TELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANN 655
T LD A A L+V+ P+ P DLELTD ++SV+L+W PGD NN
Sbjct: 614 TTLDSVSASAVLSVV---------------DVPNPPFDLELTDQLDKSVQLSWTPGDDNN 658
Query: 656 SPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSL 715
SPIT +++++E+ +PG+WH ++ G+ +A L+LSPYVNY FRV+A+N +G S PS
Sbjct: 659 SPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSE 718
Query: 716 PSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREA 775
SE+Y T + P+ NP V+G G+ +N+ ITW P+N + GP L+Y V WR+++ +
Sbjct: 719 ASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDE 778
Query: 776 WNNVTVWG-SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPS-APRRFRV 833
W +V V S+Y+V TP +VPY I+VQA ND G PEP V+G+SGEDLP AP RV
Sbjct: 779 WTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRV 838
Query: 834 RQPNLETINLEWDHP--EHPNGIMIGYTLKY-VAFNGTKVGKQIVE----NFSPNQTKFT 886
N + WD + G + GY + Y + +K ++ +E F ++T
Sbjct: 839 NVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGM 898
Query: 887 VQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEA--TPTAAPPTLPPTTVGATGAVS 944
+ +P S Y TL+ R G G E PA P+ TP P +
Sbjct: 899 LPGLEPFSHY--TLNVRVVNGKG-----EGPASPDRVFNTPEGVPS-------------A 938
Query: 945 STDATAIAATTEATTVPIIPTVAPTTIATTTTVATTTTTTAAATTTTESPPTTTSGTKIH 1004
+ + T ++ T+ P P I T T+
Sbjct: 939 PSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTL--------------------------- 971
Query: 1005 ESAPDEQSIWNVTVLPNSKWANITWKHNFGPGTDFVVEYIDSNHTKKTVPVKAQAQPIQL 1064
K+ I H GP D I +N T+ T L
Sbjct: 972 ------------------KYQPINSTHELGPLVDL---KIPANKTRWT-----------L 999
Query: 1065 TDLYPGMTYTLRVYSRDNEGISSTVITFMTST---AYTNNQADIATQGWFIGLMCAIALL 1121
+L Y Y++ + G S + +T A + Q DIATQGWFIGLMCA+ALL
Sbjct: 1000 KNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMASRQVDIATQGWFIGLMCAVALL 1059
Query: 1122 VLILLIVCFIKRSRGGKYPVREKKDVPLGPE--DPKEEDGSF-DYSD-EDNKPL-QGSQT 1176
+LILLIVCFI+R++GGKYPV+EK+D PE KE+DG+F +YSD ED+KPL +GS+T
Sbjct: 1060 ILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRT 1119
Query: 1177 SLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAI 1236
D T+K+++SDDSLVDYGEG GQFNEDGSFIGQY+ KK+KE EGNESSEA SPVNA+
Sbjct: 1120 PSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAM 1179
Query: 1237 YS 1238
S
Sbjct: 1180 NS 1181
>gi|27894376 cell adhesion molecule with homology to L1CAM precursor
[Homo sapiens]
Length = 1224
Score = 709 bits (1831), Expect = 0.0
Identities = 456/1270 (35%), Positives = 642/1270 (50%), Gaps = 109/1270 (8%)
Query: 15 LLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNIL-IECEAKGNPAPSF 73
+ LL AIEIP + + Q PTI KQS K + P D IECEAKGNP P+F
Sbjct: 15 MFLLLKFSKAIEIP------SSVQQVPTIIKQS-KVQVAFPFDEYFQIECEAKGNPEPTF 67
Query: 74 HWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIR 133
WT++ F D R+ SGT I + G ++G+Y+CFA NK G A+S I
Sbjct: 68 SWTKDGNPFYFT-DHRIIPSNNSGTFRIP--NEGHISHFQGKYRCFASNKLGIAMSEEIE 124
Query: 134 LQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGH 193
V P +PKE +DP+ V+EG P+ L CNPP GLP I+WM+ +E I QD+RV
Sbjct: 125 FIVPSVPKFPKEKIDPLEVEEGDPIVLPCNPPKGLPPLHIYWMNIELEHIEQDERVYMSQ 184
Query: 194 NGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTR---------------- 237
GDLYF+NV +D + DY C A F TI QK P L V + +
Sbjct: 185 KGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMPMKLTVNSLKHANDSSSSTEIGSKAN 244
Query: 238 GVAERTPSFMYP---QGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKF 294
+ +R P + P G+ SS +L+G LLLEC A G+PTP + W K GGDLP +
Sbjct: 245 SIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGRETK 304
Query: 295 ENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDG 354
EN+ K L+I NVS +D G Y C ASN +G+ H V V+ P W +P++ + + G +G
Sbjct: 305 ENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEPPRWTKKPQSAVYSTGSNG 364
Query: 355 RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTII-----FRDTQISSRAVYQCN 409
L+C A G P+PT++W VNG P+ + P AGD + F + Q + AVYQC
Sbjct: 365 ILLCEAEGEPQPTIKWRVNGSPVDNHP------FAGDVVFPREISFTNLQPNHTAVYQCE 418
Query: 410 TSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQ 469
SN HG +LANA + V+DV P + + + ++ L C FF SP + W K +
Sbjct: 419 ASNVHGTILANANIDVVDVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEE 478
Query: 470 GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE 529
L+G YH+YENG+L+I +ED G Y+C N +GK L++++ T++ P+
Sbjct: 479 VKPLEGRRYHIYENGTLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPK 538
Query: 530 DQVARRGTTVQLECRVKHDPSLK--LTVSWLKDDEPLYIGN----RMKKEDDSLTIFGVA 583
+ + ++L C K D LK L +SW KD E I R+ + +LTI V
Sbjct: 539 NPRIPKLHMLELHCESKCDSHLKHSLKLSWSKDGEAFEINGTEDGRIIIDGANLTISNVT 598
Query: 584 ERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERS 643
DQG Y C A T LD +TVL PD P +L L++ RS
Sbjct: 599 LEDQGIYCCSAHTALDSAADITQVTVL---------------DVPDPPENLHLSERQNRS 643
Query: 644 VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVI 703
VRLTW G +NS I++Y+V+FE ++ +PG W + ++ G + +L L+P+V YQFRVI
Sbjct: 644 VRLTWEAGADHNSNISEYIVEFEGNKEEPGRWEELTRVQGKKTTVILPLAPFVRYQFRVI 703
Query: 704 AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY 763
A+NEVG S PS PS+ + T A P+ NP +++ + ++ M I W P+ + GP L Y
Sbjct: 704 AVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKWEPLKSMEQNGPGLEY 763
Query: 764 IVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGED 823
V W+ + W TV V VY PY+++VQA N G GP+P+SV YSGED
Sbjct: 764 RVTWKPQGAPVEWEEETVTNHTLRVMTPAVYAPYDVKVQAINQLGSGPDPQSVTLYSGED 823
Query: 824 LP-SAPRRFRVRQPNLETINLEWD--HPEHPNGIMIGYTLKY----VAFNGTKVGKQI-V 875
P +AP V N + + W + +G + GY + + +G K++ +
Sbjct: 824 YPDTAPVIHGVDVINSTLVKVTWSTVPKDRVHGRLKGYQINWWKTKSLLDGRTHPKEVNI 883
Query: 876 ENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAPPTLP-- 933
FS + V D S + T+ A G+G P +E P +P
Sbjct: 884 LRFSGQRNSGMVPSLDAFSEFHLTVLAYNSKGAG---------PESEPYIFQTPEGVPEQ 934
Query: 934 PTTVGATGAVSSTDATAIAATTEATTVPIIPTVAPTTIATTT----TVATTTTTTAAATT 989
PT + V AT + + + I T + TT + +
Sbjct: 935 PTFLKVI-KVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYEIGELNDINITTPSKPS 993
Query: 990 TTESPPTTTSGTKIHESAPDEQSIWNVTVLPNSKWANITWKHNFGPGTDFVVEYIDSNHT 1049
S T+ K + A Q +S G G+ + + N T
Sbjct: 994 WHLSNLNATTKYKFYLRACTSQGCGKPITEESS---------TLGEGSKGIGKISGVNLT 1044
Query: 1050 KKTVPVKAQAQPIQLTDLYPGMTYTLRVYSR---DNEGISSTVITFMTSTAYTNNQADIA 1106
+KT P++ PG + +R+ ++ DN+ I VI Y DI+
Sbjct: 1045 QKTHPIEV---------FEPGAEHIVRLMTKNWGDNDSIFQDVIE-TRGREYAGLYDDIS 1094
Query: 1107 TQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSF-DYSD 1165
TQGWFIGLMCAIALL L+LL VCF+KR+RGGKY V+EK+D+ PE +D +F +YSD
Sbjct: 1095 TQGWFIGLMCAIALLTLLLLTVCFVKRNRGGKYSVKEKEDLHPDPEIQSVKDETFGEYSD 1154
Query: 1166 EDNKPLQGSQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNE 1225
D KPL+GS SL+ ++ ES DSLV+YGEG G F+EDGSFIG Y K+K E N
Sbjct: 1155 SDEKPLKGSLRSLNRDMQPTESADSLVEYGEGDHGLFSEDGSFIGAYAGSKEKGSVESNG 1214
Query: 1226 SSEATSPVNA 1235
SS AT P+ A
Sbjct: 1215 SSTATFPLRA 1224
>gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo
sapiens]
Length = 1248
Score = 624 bits (1608), Expect = e-178
Identities = 342/892 (38%), Positives = 485/892 (54%), Gaps = 25/892 (2%)
Query: 33 IQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSM 92
I EL +PP IT+QS + +V P D+I ++CEA G P F WTR+ F ++ V++
Sbjct: 22 IPEELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTV 81
Query: 93 RR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPV 150
+ SG+ I + + ++G Y+CFA NK GTA+S+ IRL +P WPKE + PV
Sbjct: 82 YQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPV 141
Query: 151 VVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTD 210
V+EG + L CNPPP I+WM+S + I QD+RV+ G NG+LYF+NV+ D +D
Sbjct: 142 EVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSD 201
Query: 211 YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIA 270
Y C+A F T TI QK P L+V T + +R P ++P ++S + L+G L+LECIA
Sbjct: 202 YICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIA 261
Query: 271 SGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTIS 330
G PTP I W + G +P+D+ ++N NK L++ V EED GEY CLA N +GS RH
Sbjct: 262 EGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYY 321
Query: 331 VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG 390
V V+AAPYWL +P++ + PGE RL C+ G P+P V W +NG P++ + +
Sbjct: 322 VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQR 381
Query: 391 DTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRL 450
+I + Q S V QC N HG LLANA++ V+ +P ++L+ NQ + + L
Sbjct: 382 GALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYL 441
Query: 451 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKA 510
C FG+P+P+++W + L + Y NG+L I+ ++ D G Y C+A N
Sbjct: 442 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNV 501
Query: 511 ENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY-IGNR 569
L+VKD T+I + P + ++G+ V C+ DPSL+ +++W D L +G+
Sbjct: 502 TIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDS 561
Query: 570 MKK--EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGR 627
K ED L I + DQG+Y+CVASTELD ++A L V+ P RL
Sbjct: 562 DKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPG-PVPRLVL----- 615
Query: 628 PDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNS 687
DL L L + VR++W P + +N+PI Y ++FE+ + P W+ K PG+ S
Sbjct: 616 ----SDLHL--LTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTS 669
Query: 688 AVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEIT 747
L+LSPYV+Y FRV AIN+ G PS SE T A PE NP DVKGEG NM IT
Sbjct: 670 TTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVIT 729
Query: 748 WTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDF 807
W P+ P ++Y V+WR + TR W V VV T +VPYEI+VQA N
Sbjct: 730 WKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQ 789
Query: 808 GKGPEPESVIGYSGEDLPSA-PRRFRVRQPNLETINLEWDHPE--HPNGIMIGYTLKYVA 864
GKGPEP+ IGYSGED P A P + N + ++W + G + GY + Y
Sbjct: 790 GKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWR 849
Query: 865 FNG-TKVGKQIVEN----FSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEA 911
K K+ + N T + P S Y + A GSG A
Sbjct: 850 EGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPA 901
Score = 151 bits (382), Expect = 3e-36
Identities = 208/910 (22%), Positives = 346/910 (38%), Gaps = 72/910 (7%)
Query: 41 PTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLV 100
P K++ K V+ +++++ C + P + NS+ +I +D RV+M +
Sbjct: 131 PKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYF 190
Query: 101 IDFRSGGRPEEYEGEYQCFARNKFGTALSNR----IRLQVSKSP-------LWPKENLDP 149
+ + + +Y C A + + +R++ + S L+P +
Sbjct: 191 ANVLTS----DNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSH 246
Query: 150 VVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 209
+V +G PL L+C G P+P I W+ S P+ D+ Q HN L V +D
Sbjct: 247 LVALQGQPLVLECIAE-GFPTPTIKWLRPS-GPMPADRVTYQNHNKTLQLLKVGEED-DG 303
Query: 210 DYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECI 269
+Y C A ++ + + V + S +Y G + L+C
Sbjct: 304 EYRCLAENSLGSA---RHAYYVTVEAAPYWLHKPQSHLYGPGETAR----------LDCQ 350
Query: 270 ASGVPTPDIAWYKKG---GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIR 326
G P P++ W G +L D+ K+ AL ++NV D+ C A N+ G +
Sbjct: 351 VQGRPQPEVTWRINGIPVEELAKDQ-KYRIQRGALILSNVQPSDTMVTQCEARNRHGLLL 409
Query: 327 HTISVRVKAAPYWLDEPKN--LILAPGEDGRLVCRANGNPKPTVQWMVNGEP--LQSAPP 382
+ V P + N + G L+C+A G P P+VQW+ LQ
Sbjct: 410 ANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERF 469
Query: 383 NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRV 442
P A T+ RD Q + Y C +N+ + A + V D PR+ + +
Sbjct: 470 FP---YANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKK 526
Query: 443 ILYNRTRLDCPFFGSPIPTLRWFKNGQG-SNLDGGNYHVYENGSLEIKMIRKEDQGIYTC 501
F S P++ W +G+ L + + E+G L I + DQG Y+C
Sbjct: 527 GSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSC 586
Query: 502 VATNILGKAENQVRL-EVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 560
VA+ L E++ +L V P + R+ + Q + RV P+ K
Sbjct: 587 VASTELDVVESRAQLLVVGSPGPVPRLVLSDLH---LLTQSQVRVSWSPAEDHNAPIEKY 643
Query: 561 DEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLAD-QATPTNR 619
D ++ SL G +Q S T S + + + +P +
Sbjct: 644 DIEFEDKEMAPEKWYSL---GKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSE 700
Query: 620 LAALPKGRPDR-PRDLELTDLAERSVRLTWIPGDAN--NSPITDYVVQFEEDQFQPGVWH 676
P+ P++ P D++ ++ +TW P N+P Y VQ+ Q G W
Sbjct: 701 TVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRP-QGTRGPWQ 759
Query: 677 DHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAP-PESNPGDVK 735
+ + V S +V Y+ +V A+N G P SG P++ P
Sbjct: 760 E--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPE--PQVTIGYSGEDYPQAIPELEG 815
Query: 736 GEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVV------- 788
E + + + W P++ G Y V + R ++ + + VV
Sbjct: 816 IEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSV 875
Query: 789 ---GQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEW 845
G P Y Y + VQA N G GP E + E +P P + + ++ L W
Sbjct: 876 ILSGLRP-YSSYHLEVQAFNGRGSGPASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRW 933
Query: 846 DHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQ 905
P NG++ GY L Y + G+ P + P RYRF L A T+
Sbjct: 934 QPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTK 993
Query: 906 VGSGEAVTEE 915
G GEA+ E
Sbjct: 994 EGPGEAIVRE 1003
Score = 149 bits (377), Expect = 1e-35
Identities = 77/138 (55%), Positives = 98/138 (71%), Gaps = 1/138 (0%)
Query: 1103 ADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSF- 1161
A AT+GWFIG + AI LL+L+LLI+CFIKRS+GGKY V++K+D + E +D +F
Sbjct: 1110 AGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFG 1169
Query: 1162 DYSDEDNKPLQGSQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEET 1221
+YSD + K SQ SL+G IK SDDSL DYG + QFNEDGSFIGQY+ KK+KE
Sbjct: 1170 EYSDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAA 1229
Query: 1222 EGNESSEATSPVNAIYSL 1239
GN+SS ATSP+N +L
Sbjct: 1230 GGNDSSGATSPINPAVAL 1247
Score = 38.1 bits (87), Expect = 0.052
Identities = 33/136 (24%), Positives = 54/136 (39%), Gaps = 6/136 (4%)
Query: 624 PKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEE-DQFQPGVWHDHSKYP 682
P+G P P L L + S+ L W P ++N +T YV+ + D+ G + + P
Sbjct: 909 PEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDP 968
Query: 683 GSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSL-PSERYRTSGAPPESNPGDVKGEGTRK 741
+ LSP++ Y+F++ A + G + SG N GE
Sbjct: 969 ELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGE---- 1024
Query: 742 NNMEITWTPMNATSAF 757
N ++W P F
Sbjct: 1025 NYSVVSWVPKEGQCNF 1040
>gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 1253
Score = 620 bits (1599), Expect = e-177
Identities = 345/908 (37%), Positives = 492/908 (54%), Gaps = 31/908 (3%)
Query: 17 CLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWT 76
CLL I+IP + + + +PP IT+QS + +V P D+I ++CEA G P F WT
Sbjct: 17 CLL-----IQIPEEYE-GHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWT 70
Query: 77 RNSRFFNIAKDPRVSMRR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRL 134
R+ F ++ V++ + SG+ I + + ++G Y+CFA NK GTA+S+ IRL
Sbjct: 71 RDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRL 130
Query: 135 QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHN 194
+P WPKE + PV V+EG + L CNPPP I+WM+S + I QD+RV+ G N
Sbjct: 131 MAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQN 190
Query: 195 GDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTAS 254
G+LYF+NV+ D +DY C+A F T TI QK P L+V T + +R P ++P ++S
Sbjct: 191 GNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSS 250
Query: 255 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEY 314
+ L+G L+LECIA G PTP I W + G +P+D+ ++N NK L++ V EED GEY
Sbjct: 251 HLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEY 310
Query: 315 FCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNG 374
CLA N +GS RH V V+AAPYWL +P++ + PGE RL C+ G P+P V W +NG
Sbjct: 311 RCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 370
Query: 375 EPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLS 434
P++ + + +I + Q S V QC N HG LLANA++ V+ +P ++L+
Sbjct: 371 IPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 430
Query: 435 PRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKE 494
NQ + + L C FG+P+P+++W + L + Y NG+L I+ ++
Sbjct: 431 ADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQAN 490
Query: 495 DQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLT 554
D G Y C+A N L+VKD T+I + P + ++G+ V C+ DPSL+ +
Sbjct: 491 DTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPS 550
Query: 555 VSWLKDDEPLY-IGNRMKK--EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLA 611
++W D L +G+ K ED L I + DQG+Y+CVASTELD ++A L V+
Sbjct: 551 ITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVG 610
Query: 612 DQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQ 671
P RL DL L L + VR++W P + +N+PI Y ++FE+ +
Sbjct: 611 SPG-PVPRLVL---------SDLHL--LTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMA 658
Query: 672 PGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNP 731
P W+ K PG+ S L+LSPYV+Y FRV AIN+ G PS SE T A PE NP
Sbjct: 659 PEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNP 718
Query: 732 GDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQT 791
DVKGEG NM ITW P+ P ++Y V+WR + TR W V VV T
Sbjct: 719 VDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNT 778
Query: 792 PVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSA-PRRFRVRQPNLETINLEWDHPE- 849
+VPYEI+VQA N GKGPEP+ IGYSGED P A P + N + ++W +
Sbjct: 779 STFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDL 838
Query: 850 -HPNGIMIGYTLKYVAFNG-TKVGKQIVEN----FSPNQTKFTVQRTDPVSRYRFTLSAR 903
G + GY + Y K K+ + N T + P S Y + A
Sbjct: 839 AQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAF 898
Query: 904 TQVGSGEA 911
GSG A
Sbjct: 899 NGRGSGPA 906
Score = 151 bits (382), Expect = 3e-36
Identities = 208/910 (22%), Positives = 346/910 (38%), Gaps = 72/910 (7%)
Query: 41 PTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLV 100
P K++ K V+ +++++ C + P + NS+ +I +D RV+M +
Sbjct: 136 PKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYF 195
Query: 101 IDFRSGGRPEEYEGEYQCFARNKFGTALSNR----IRLQVSKSP-------LWPKENLDP 149
+ + + +Y C A + + +R++ + S L+P +
Sbjct: 196 ANVLTS----DNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSH 251
Query: 150 VVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 209
+V +G PL L+C G P+P I W+ S P+ D+ Q HN L V +D
Sbjct: 252 LVALQGQPLVLECIAE-GFPTPTIKWLRPS-GPMPADRVTYQNHNKTLQLLKVGEED-DG 308
Query: 210 DYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECI 269
+Y C A ++ + + V + S +Y G + L+C
Sbjct: 309 EYRCLAENSLGSA---RHAYYVTVEAAPYWLHKPQSHLYGPGETAR----------LDCQ 355
Query: 270 ASGVPTPDIAWYKKG---GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIR 326
G P P++ W G +L D+ K+ AL ++NV D+ C A N+ G +
Sbjct: 356 VQGRPQPEVTWRINGIPVEELAKDQ-KYRIQRGALILSNVQPSDTMVTQCEARNRHGLLL 414
Query: 327 HTISVRVKAAPYWLDEPKN--LILAPGEDGRLVCRANGNPKPTVQWMVNGEP--LQSAPP 382
+ V P + N + G L+C+A G P P+VQW+ LQ
Sbjct: 415 ANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERF 474
Query: 383 NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRV 442
P A T+ RD Q + Y C +N+ + A + V D PR+ + +
Sbjct: 475 FP---YANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKK 531
Query: 443 ILYNRTRLDCPFFGSPIPTLRWFKNGQG-SNLDGGNYHVYENGSLEIKMIRKEDQGIYTC 501
F S P++ W +G+ L + + E+G L I + DQG Y+C
Sbjct: 532 GSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSC 591
Query: 502 VATNILGKAENQVRL-EVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 560
VA+ L E++ +L V P + R+ + Q + RV P+ K
Sbjct: 592 VASTELDVVESRAQLLVVGSPGPVPRLVLSDLH---LLTQSQVRVSWSPAEDHNAPIEKY 648
Query: 561 DEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLAD-QATPTNR 619
D ++ SL G +Q S T S + + + +P +
Sbjct: 649 DIEFEDKEMAPEKWYSL---GKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSE 705
Query: 620 LAALPKGRPDR-PRDLELTDLAERSVRLTWIPGDAN--NSPITDYVVQFEEDQFQPGVWH 676
P+ P++ P D++ ++ +TW P N+P Y VQ+ Q G W
Sbjct: 706 TVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRP-QGTRGPWQ 764
Query: 677 DHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAP-PESNPGDVK 735
+ + V S +V Y+ +V A+N G P SG P++ P
Sbjct: 765 E--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPE--PQVTIGYSGEDYPQAIPELEG 820
Query: 736 GEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVV------- 788
E + + + W P++ G Y V + R ++ + + VV
Sbjct: 821 IEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSV 880
Query: 789 ---GQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEW 845
G P Y Y + VQA N G GP E + E +P P + + ++ L W
Sbjct: 881 ILSGLRP-YSSYHLEVQAFNGRGSGPASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRW 938
Query: 846 DHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQ 905
P NG++ GY L Y + G+ P + P RYRF L A T+
Sbjct: 939 QPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTK 998
Query: 906 VGSGEAVTEE 915
G GEA+ E
Sbjct: 999 EGPGEAIVRE 1008
Score = 149 bits (377), Expect = 1e-35
Identities = 77/138 (55%), Positives = 98/138 (71%), Gaps = 1/138 (0%)
Query: 1103 ADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSF- 1161
A AT+GWFIG + AI LL+L+LLI+CFIKRS+GGKY V++K+D + E +D +F
Sbjct: 1115 AGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFG 1174
Query: 1162 DYSDEDNKPLQGSQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEET 1221
+YSD + K SQ SL+G IK SDDSL DYG + QFNEDGSFIGQY+ KK+KE
Sbjct: 1175 EYSDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAA 1234
Query: 1222 EGNESSEATSPVNAIYSL 1239
GN+SS ATSP+N +L
Sbjct: 1235 GGNDSSGATSPINPAVAL 1252
Score = 38.1 bits (87), Expect = 0.052
Identities = 33/136 (24%), Positives = 54/136 (39%), Gaps = 6/136 (4%)
Query: 624 PKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEE-DQFQPGVWHDHSKYP 682
P+G P P L L + S+ L W P ++N +T YV+ + D+ G + + P
Sbjct: 914 PEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDP 973
Query: 683 GSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSL-PSERYRTSGAPPESNPGDVKGEGTRK 741
+ LSP++ Y+F++ A + G + SG N GE
Sbjct: 974 ELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGE---- 1029
Query: 742 NNMEITWTPMNATSAF 757
N ++W P F
Sbjct: 1030 NYSVVSWVPKEGQCNF 1045
>gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 1257
Score = 620 bits (1599), Expect = e-177
Identities = 345/908 (37%), Positives = 492/908 (54%), Gaps = 31/908 (3%)
Query: 17 CLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWT 76
CLL I+IP + + + +PP IT+QS + +V P D+I ++CEA G P F WT
Sbjct: 17 CLL-----IQIPEEYE-GHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWT 70
Query: 77 RNSRFFNIAKDPRVSMRR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRL 134
R+ F ++ V++ + SG+ I + + ++G Y+CFA NK GTA+S+ IRL
Sbjct: 71 RDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRL 130
Query: 135 QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHN 194
+P WPKE + PV V+EG + L CNPPP I+WM+S + I QD+RV+ G N
Sbjct: 131 MAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQN 190
Query: 195 GDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTAS 254
G+LYF+NV+ D +DY C+A F T TI QK P L+V T + +R P ++P ++S
Sbjct: 191 GNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSS 250
Query: 255 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEY 314
+ L+G L+LECIA G PTP I W + G +P+D+ ++N NK L++ V EED GEY
Sbjct: 251 HLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEY 310
Query: 315 FCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNG 374
CLA N +GS RH V V+AAPYWL +P++ + PGE RL C+ G P+P V W +NG
Sbjct: 311 RCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 370
Query: 375 EPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLS 434
P++ + + +I + Q S V QC N HG LLANA++ V+ +P ++L+
Sbjct: 371 IPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 430
Query: 435 PRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKE 494
NQ + + L C FG+P+P+++W + L + Y NG+L I+ ++
Sbjct: 431 ADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQAN 490
Query: 495 DQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLT 554
D G Y C+A N L+VKD T+I + P + ++G+ V C+ DPSL+ +
Sbjct: 491 DTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPS 550
Query: 555 VSWLKDDEPLY-IGNRMKK--EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLA 611
++W D L +G+ K ED L I + DQG+Y+CVASTELD ++A L V+
Sbjct: 551 ITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVG 610
Query: 612 DQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQ 671
P RL DL L L + VR++W P + +N+PI Y ++FE+ +
Sbjct: 611 SPG-PVPRLVL---------SDLHL--LTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMA 658
Query: 672 PGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNP 731
P W+ K PG+ S L+LSPYV+Y FRV AIN+ G PS SE T A PE NP
Sbjct: 659 PEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNP 718
Query: 732 GDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQT 791
DVKGEG NM ITW P+ P ++Y V+WR + TR W V VV T
Sbjct: 719 VDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNT 778
Query: 792 PVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSA-PRRFRVRQPNLETINLEWDHPE- 849
+VPYEI+VQA N GKGPEP+ IGYSGED P A P + N + ++W +
Sbjct: 779 STFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDL 838
Query: 850 -HPNGIMIGYTLKYVAFNG-TKVGKQIVEN----FSPNQTKFTVQRTDPVSRYRFTLSAR 903
G + GY + Y K K+ + N T + P S Y + A
Sbjct: 839 AQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAF 898
Query: 904 TQVGSGEA 911
GSG A
Sbjct: 899 NGRGSGPA 906
Score = 151 bits (382), Expect = 3e-36
Identities = 208/910 (22%), Positives = 346/910 (38%), Gaps = 72/910 (7%)
Query: 41 PTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLV 100
P K++ K V+ +++++ C + P + NS+ +I +D RV+M +
Sbjct: 136 PKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYF 195
Query: 101 IDFRSGGRPEEYEGEYQCFARNKFGTALSNR----IRLQVSKSP-------LWPKENLDP 149
+ + + +Y C A + + +R++ + S L+P +
Sbjct: 196 ANVLTS----DNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSH 251
Query: 150 VVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 209
+V +G PL L+C G P+P I W+ S P+ D+ Q HN L V +D
Sbjct: 252 LVALQGQPLVLECIAE-GFPTPTIKWLRPS-GPMPADRVTYQNHNKTLQLLKVGEED-DG 308
Query: 210 DYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECI 269
+Y C A ++ + + V + S +Y G + L+C
Sbjct: 309 EYRCLAENSLGSA---RHAYYVTVEAAPYWLHKPQSHLYGPGETAR----------LDCQ 355
Query: 270 ASGVPTPDIAWYKKG---GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIR 326
G P P++ W G +L D+ K+ AL ++NV D+ C A N+ G +
Sbjct: 356 VQGRPQPEVTWRINGIPVEELAKDQ-KYRIQRGALILSNVQPSDTMVTQCEARNRHGLLL 414
Query: 327 HTISVRVKAAPYWLDEPKN--LILAPGEDGRLVCRANGNPKPTVQWMVNGEP--LQSAPP 382
+ V P + N + G L+C+A G P P+VQW+ LQ
Sbjct: 415 ANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERF 474
Query: 383 NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRV 442
P A T+ RD Q + Y C +N+ + A + V D PR+ + +
Sbjct: 475 FP---YANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKK 531
Query: 443 ILYNRTRLDCPFFGSPIPTLRWFKNGQG-SNLDGGNYHVYENGSLEIKMIRKEDQGIYTC 501
F S P++ W +G+ L + + E+G L I + DQG Y+C
Sbjct: 532 GSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSC 591
Query: 502 VATNILGKAENQVRL-EVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 560
VA+ L E++ +L V P + R+ + Q + RV P+ K
Sbjct: 592 VASTELDVVESRAQLLVVGSPGPVPRLVLSDLH---LLTQSQVRVSWSPAEDHNAPIEKY 648
Query: 561 DEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLAD-QATPTNR 619
D ++ SL G +Q S T S + + + +P +
Sbjct: 649 DIEFEDKEMAPEKWYSL---GKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSE 705
Query: 620 LAALPKGRPDR-PRDLELTDLAERSVRLTWIPGDAN--NSPITDYVVQFEEDQFQPGVWH 676
P+ P++ P D++ ++ +TW P N+P Y VQ+ Q G W
Sbjct: 706 TVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRP-QGTRGPWQ 764
Query: 677 DHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAP-PESNPGDVK 735
+ + V S +V Y+ +V A+N G P SG P++ P
Sbjct: 765 E--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPE--PQVTIGYSGEDYPQAIPELEG 820
Query: 736 GEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVV------- 788
E + + + W P++ G Y V + R ++ + + VV
Sbjct: 821 IEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSV 880
Query: 789 ---GQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEW 845
G P Y Y + VQA N G GP E + E +P P + + ++ L W
Sbjct: 881 ILSGLRP-YSSYHLEVQAFNGRGSGPASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRW 938
Query: 846 DHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQ 905
P NG++ GY L Y + G+ P + P RYRF L A T+
Sbjct: 939 QPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTK 998
Query: 906 VGSGEAVTEE 915
G GEA+ E
Sbjct: 999 EGPGEAIVRE 1008
Score = 144 bits (362), Expect = 7e-34
Identities = 77/142 (54%), Positives = 98/142 (69%), Gaps = 5/142 (3%)
Query: 1103 ADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSF- 1161
A AT+GWFIG + AI LL+L+LLI+CFIKRS+GGKY V++K+D + E +D +F
Sbjct: 1115 AGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFG 1174
Query: 1162 DY----SDEDNKPLQGSQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKD 1217
+Y SD + K SQ SL+G IK SDDSL DYG + QFNEDGSFIGQY+ KK+
Sbjct: 1175 EYRSLESDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKE 1234
Query: 1218 KEETEGNESSEATSPVNAIYSL 1239
KE GN+SS ATSP+N +L
Sbjct: 1235 KEAAGGNDSSGATSPINPAVAL 1256
Score = 38.1 bits (87), Expect = 0.052
Identities = 33/136 (24%), Positives = 54/136 (39%), Gaps = 6/136 (4%)
Query: 624 PKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEE-DQFQPGVWHDHSKYP 682
P+G P P L L + S+ L W P ++N +T YV+ + D+ G + + P
Sbjct: 914 PEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDP 973
Query: 683 GSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSL-PSERYRTSGAPPESNPGDVKGEGTRK 741
+ LSP++ Y+F++ A + G + SG N GE
Sbjct: 974 ELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGE---- 1029
Query: 742 NNMEITWTPMNATSAF 757
N ++W P F
Sbjct: 1030 NYSVVSWVPKEGQCNF 1045
>gi|4827022 contactin 2 precursor [Homo sapiens]
Length = 1040
Score = 348 bits (893), Expect = 2e-95
Identities = 266/917 (29%), Positives = 406/917 (44%), Gaps = 72/917 (7%)
Query: 57 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 116
+ +L+ C A+ +P ++ W N + +P + G LVI + G Y
Sbjct: 55 EQVLLACRARASPPATYRWKMNGTEMKL--EPGSRHQLVGGNLVI---MNPTKAQDAGVY 109
Query: 117 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWM 176
QC A N GT +S L+ + KE DPV EG + L CNPP P W+
Sbjct: 110 QCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWL 169
Query: 177 SSSMEPI--TQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQK-NPFTLKV 233
+ T + G+LY + D+ +YSC A H + + + F
Sbjct: 170 LNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLG-NYSCLATSHMDFSTKSVFSKFAQLN 228
Query: 234 LTTRGVAERTPSFM--YPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDK 291
L PS +P T + L G + LEC A G P P I W K G L
Sbjct: 229 LAAEDTRLFAPSIKARFPAETYA----LVGQQVTLECFAFGNPVPRIKWRKVDGSL---S 281
Query: 292 AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVR--VKAAPYWLDEPKNLILA 349
++ L+I +VS ED G Y C A N G R T+ R V+A P WL +
Sbjct: 282 PQWTTAEPTLQIPSVSFEDEGTYECEAENSKG--RDTVQGRIIVQAQPEWLKVISDTEAD 339
Query: 350 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN 409
G + R C A G P+PTV+W+ NGEPL S N +AGD + F + +YQC
Sbjct: 340 IGSNLRWGCAAAGKPRPTVRWLRNGEPLASQ--NRVEVLAGD-LRFSKLSLEDSGMYQCV 396
Query: 410 TSNEHGYLLANAFVSVLDVPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG 468
N+HG + A+A ++V + P L+P +LI + C +P + W K G
Sbjct: 397 AENKHGTIYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSK-G 455
Query: 469 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMP 528
++ V +G+L I+ I + D+G YTC A N +GKA + L V+D T+I P
Sbjct: 456 TEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTGILSVRDATKITLAP 515
Query: 529 EDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPL--------YIGNRMKKEDDSLTIF 580
G + L+C HDP++ LT +W DD P+ Y +K+ LTI
Sbjct: 516 SSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTIL 575
Query: 581 GVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLA 640
R G YTC+A T +D + + L +G P P + + D+
Sbjct: 576 NAQLRHGGKYTCMAQTVVD---------------SASKEATVLVRGPPGPPGGVVVRDIG 620
Query: 641 ERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSV-----NSAVLRLSPY 695
+ +++L+W G N+SPI Y +Q G W P ++ + VL L+P+
Sbjct: 621 DTTIQLSWSRGFDNHSPIAKYTLQARTP--PAGKWKQVRTNPANIEGNAETAQVLGLTPW 678
Query: 696 VNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATS 755
++Y+FRVIA N +G+ PS PS + RT A P P + G G + + WTPM+
Sbjct: 679 MDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWTPMSREY 738
Query: 756 AFGPNLRYIVKWRRRETREAWNNVTVWGS---RYVVGQTPV--YVPYEIRVQAENDFGKG 810
G Y++ +RR+ + W V G+ +V V Y P+E+++++ N G G
Sbjct: 739 QNGDGFGYLLSFRRQGSTH-WQTARVPGADAQYFVYSNESVRPYTPFEVKIRSYNRRGDG 797
Query: 811 PEPESVIGYSGEDLPS-APRRFRVRQPNLETINLEWDHPEHP-NGIMIGYTLKYVAFNGT 868
PE + + YS E+ P AP + + + +N+ W+ + NGI++GY ++Y
Sbjct: 798 PESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQQDMNGILLGYEIRYWKAGDK 857
Query: 869 KVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAA 928
+ V + T V P ++Y T+ A + G+G A +P AT
Sbjct: 858 EAAADRVRT-AGLDTSARVSGLHPNTKYHVTVRAYNRAGTGPA------SPSANATTMKP 910
Query: 929 PPTLPPTTVGATGAVSS 945
PP PP + T + SS
Sbjct: 911 PPRRPPGNISWTFSSSS 927
Score = 72.4 bits (176), Expect = 3e-12
Identities = 88/337 (26%), Positives = 125/337 (37%), Gaps = 59/337 (17%)
Query: 50 DHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRP 109
D D N+ C A G P P+ W RN +P S + R L D R
Sbjct: 335 DTEADIGSNLRWGCAAAGKPRPTVRWLRNG-------EPLAS-QNRVEVLAGDLRFSKLS 386
Query: 110 EEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPV----VVQEGAPLTLQCNPP 165
E G YQC A NK GT ++ +++ L P L+PV G + + C P
Sbjct: 387 LEDSGMYQCVAENKHGTIYAS---AELAVQALAPDFRLNPVRRLIPAARGGEILIPCQ-P 442
Query: 166 PGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQ 225
P V+ W S E + RV+ +G L N+ D + Y+C F
Sbjct: 443 RAAPKAVVLW-SKGTEILVNSSRVTVTPDGTLIIRNISRSD-EGKYTC-----FAENFMG 495
Query: 226 KNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGG 285
K T +L+ R + T + SS + G +L L+C AS PT D+ +
Sbjct: 496 KANST-GILSVRDATKITLA-------PSSADINLGDNLTLQCHASHDPTMDLTFTWTLD 547
Query: 286 DLPSDKAKFENFNKALRITNVSE------------EDSGEYFCLASNKMGSIRHTISVRV 333
D P D F+ R TNV E G+Y C+A + S +V V
Sbjct: 548 DFPID---FDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLV 604
Query: 334 KAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 370
+ PG G +V R G+ + W
Sbjct: 605 RG-------------PPGPPGGVVVRDIGDTTIQLSW 628
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 346 bits (888), Expect = 7e-95
Identities = 265/918 (28%), Positives = 405/918 (44%), Gaps = 77/918 (8%)
Query: 50 DHIVDPRDN----ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRS 105
D I+ P D+ + + CE +GNP PS+ W RN ++ D R S+ GT +I S
Sbjct: 106 DDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLI--DGTFIISNPS 163
Query: 106 GGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPP 165
+ G YQC A N G+ LS LQ + + V V+EG + L C+PP
Sbjct: 164 EAKDS---GHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPP 220
Query: 166 PGLPSPVIFWMSSSMEP-ITQDKR--VSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHT 222
P P + W+ + + +D R +SQ G+LY S V D+ + Y C + T+
Sbjct: 221 PHSPEIIYSWVFNEFPSFVAEDSRRFISQ-ETGNLYISKVQTSDVGS-YICLVKNTVTNA 278
Query: 223 --IQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAW 280
+ P TL+ G E +P ++ +G + +EC A G P P I W
Sbjct: 279 RVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAA----KGTTVKMECFALGNPVPTITW 334
Query: 281 YKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWL 340
K G +PS KA+ L I NV +D+G Y C A N G ++V P+W+
Sbjct: 335 MKVNGYIPS-KARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWV 393
Query: 341 DEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQI 400
++ + L G R C+A G P+PT +W+ NG PL P E+ ++ +
Sbjct: 394 EKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLS---PQSRVEMVNGVLMIHNVNQ 450
Query: 401 SSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTR---LDCPFFGS 457
S +YQC N++G + A+A + +L P NQL + I+ + + ++C GS
Sbjct: 451 SDAGMYQCLAENKYGAIYASAELKILASAPTFAL--NQLKKTIIVTKDQEVVIECKPQGS 508
Query: 458 PIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLE 517
P PT+ W K G + + + +GSL I K D+G Y C N+ G AE L
Sbjct: 509 PKPTISW-KKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLS 567
Query: 518 VKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPL--------YIGNR 569
VK+PTRI P+ G ++ L C+ HD SL +T W +P+ + R
Sbjct: 568 VKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIR 627
Query: 570 MKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPD 629
+ L I + G Y C T D +A L V +G P
Sbjct: 628 AQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLV---------------RGPPG 672
Query: 630 RPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP----GSV 685
P + + ++ E + L+W P N+SPI+ Y +Q F G W P G +
Sbjct: 673 PPGIVIVEEITESTATLSWSPAADNHSPISSYNLQ-ARSPFSLG-WQTVKTVPEIITGDM 730
Query: 686 NSAV-LRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNM 744
SA+ + L+P+V Y+FRV+A N +G+ PS PS RT+ A P++ P +V G R++ +
Sbjct: 731 ESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHEL 790
Query: 745 EITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSR-----YVVGQTPVYVPYEI 799
I W P++ G YIV +R TR W V S Y P P+E+
Sbjct: 791 VIAWEPVSEEFQNGEGFGYIVAFRPNGTR-GWKEKMVTSSEASKFIYRDESVPPLTPFEV 849
Query: 800 RVQAENDFGKGPEPESVIGYSGEDLPS-APRRFRVRQPNLETINLEWDHPE----HPNGI 854
+V N+ G GP + V+ S E PS AP + ++ I + W H + P G
Sbjct: 850 KVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESLGRPQGF 909
Query: 855 MIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTE 914
+GY + + K N++ + + + Y FT+ A G G +E
Sbjct: 910 EVGYWKDMEQEDTAETVKT-----RGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSE 964
Query: 915 ESPAPPNEATPTAAPPTL 932
S A ++ P+ AP L
Sbjct: 965 VS-ATTKKSPPSQAPSNL 981
Score = 66.2 bits (160), Expect = 2e-10
Identities = 65/304 (21%), Positives = 122/304 (40%), Gaps = 38/304 (12%)
Query: 46 QSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRS 105
+ D +D + EC+A G P P++ W +N + P+ + +G L+I
Sbjct: 394 EKLNDTQLDSGSPLRWECKATGKPRPTYRWLKN----GVPLSPQSRVEMVNGVLMIH--- 446
Query: 106 GGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENL-DPVVVQEGAPLTLQCNP 164
+ G YQC A NK+G ++ ++ +P + L ++V + + ++C
Sbjct: 447 -NVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECK- 504
Query: 165 PPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQ 224
P G P P I W + ++KR++ +G L N D + Y C F
Sbjct: 505 PQGSPKPTISWKKGD-RAVRENKRIAILPDGSLRILNASKSD-EGKYVCRGENVFG---- 558
Query: 225 QKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWY--- 281
+ +++ + V E T + P+ T + G ++L C A + D+ +Y
Sbjct: 559 -----SAEIIASLSVKEPTRIELTPKRTE----LTVGESIVLNCKAIHDASLDVTFYWTL 609
Query: 282 --------KKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRV 333
++GG S +A+ + + L I N+ +G Y C S+ + V
Sbjct: 610 KGQPIDFEEEGGHFESIRAQASSAD--LMIRNILLMHAGRYGCRVQTTADSVSDEAELLV 667
Query: 334 KAAP 337
+ P
Sbjct: 668 RGPP 671
Score = 43.9 bits (102), Expect = 0.001
Identities = 38/178 (21%), Positives = 76/178 (42%), Gaps = 21/178 (11%)
Query: 37 LTQPPTITKQSAKDHIVDPRDN-ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRR 95
L PT K I+ +D ++IEC+ +G+P P+ W + R + ++ R+++
Sbjct: 476 LASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDR--AVRENKRIAILPD 533
Query: 96 SGTLVIDFRSGGRPEEYEGEYQCFARNKFGTA--LSNRIRLQVSKSPLWPKENLDPVVVQ 153
+++ + EG+Y C N FG+A +++ + ++ L PK +
Sbjct: 534 GSLRILN-----ASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKR----TELT 584
Query: 154 EGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKR-------VSQGHNGDLYFSNVML 204
G + L C V F+ + +PI ++ +Q + DL N++L
Sbjct: 585 VGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILL 642
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 346 bits (888), Expect = 7e-95
Identities = 265/918 (28%), Positives = 405/918 (44%), Gaps = 77/918 (8%)
Query: 50 DHIVDPRDN----ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRS 105
D I+ P D+ + + CE +GNP PS+ W RN ++ D R S+ GT +I S
Sbjct: 32 DDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLI--DGTFIISNPS 89
Query: 106 GGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPP 165
+ G YQC A N G+ LS LQ + + V V+EG + L C+PP
Sbjct: 90 EAKDS---GHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPP 146
Query: 166 PGLPSPVIFWMSSSMEP-ITQDKR--VSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHT 222
P P + W+ + + +D R +SQ G+LY S V D+ + Y C + T+
Sbjct: 147 PHSPEIIYSWVFNEFPSFVAEDSRRFISQ-ETGNLYISKVQTSDVGS-YICLVKNTVTNA 204
Query: 223 --IQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAW 280
+ P TL+ G E +P ++ +G + +EC A G P P I W
Sbjct: 205 RVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAA----KGTTVKMECFALGNPVPTITW 260
Query: 281 YKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWL 340
K G +PS KA+ L I NV +D+G Y C A N G ++V P+W+
Sbjct: 261 MKVNGYIPS-KARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWV 319
Query: 341 DEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQI 400
++ + L G R C+A G P+PT +W+ NG PL P E+ ++ +
Sbjct: 320 EKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLS---PQSRVEMVNGVLMIHNVNQ 376
Query: 401 SSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTR---LDCPFFGS 457
S +YQC N++G + A+A + +L P NQL + I+ + + ++C GS
Sbjct: 377 SDAGMYQCLAENKYGAIYASAELKILASAPTFAL--NQLKKTIIVTKDQEVVIECKPQGS 434
Query: 458 PIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLE 517
P PT+ W K G + + + +GSL I K D+G Y C N+ G AE L
Sbjct: 435 PKPTISW-KKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLS 493
Query: 518 VKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPL--------YIGNR 569
VK+PTRI P+ G ++ L C+ HD SL +T W +P+ + R
Sbjct: 494 VKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIR 553
Query: 570 MKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPD 629
+ L I + G Y C T D +A L V +G P
Sbjct: 554 AQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLV---------------RGPPG 598
Query: 630 RPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP----GSV 685
P + + ++ E + L+W P N+SPI+ Y +Q F G W P G +
Sbjct: 599 PPGIVIVEEITESTATLSWSPAADNHSPISSYNLQ-ARSPFSLG-WQTVKTVPEIITGDM 656
Query: 686 NSAV-LRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNM 744
SA+ + L+P+V Y+FRV+A N +G+ PS PS RT+ A P++ P +V G R++ +
Sbjct: 657 ESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHEL 716
Query: 745 EITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSR-----YVVGQTPVYVPYEI 799
I W P++ G YIV +R TR W V S Y P P+E+
Sbjct: 717 VIAWEPVSEEFQNGEGFGYIVAFRPNGTR-GWKEKMVTSSEASKFIYRDESVPPLTPFEV 775
Query: 800 RVQAENDFGKGPEPESVIGYSGEDLPS-APRRFRVRQPNLETINLEWDHPE----HPNGI 854
+V N+ G GP + V+ S E PS AP + ++ I + W H + P G
Sbjct: 776 KVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESLGRPQGF 835
Query: 855 MIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTE 914
+GY + + K N++ + + + Y FT+ A G G +E
Sbjct: 836 EVGYWKDMEQEDTAETVKT-----RGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSE 890
Query: 915 ESPAPPNEATPTAAPPTL 932
S A ++ P+ AP L
Sbjct: 891 VS-ATTKKSPPSQAPSNL 907
Score = 66.2 bits (160), Expect = 2e-10
Identities = 65/304 (21%), Positives = 122/304 (40%), Gaps = 38/304 (12%)
Query: 46 QSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRS 105
+ D +D + EC+A G P P++ W +N + P+ + +G L+I
Sbjct: 320 EKLNDTQLDSGSPLRWECKATGKPRPTYRWLKN----GVPLSPQSRVEMVNGVLMIH--- 372
Query: 106 GGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENL-DPVVVQEGAPLTLQCNP 164
+ G YQC A NK+G ++ ++ +P + L ++V + + ++C
Sbjct: 373 -NVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECK- 430
Query: 165 PPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQ 224
P G P P I W + ++KR++ +G L N D + Y C F
Sbjct: 431 PQGSPKPTISWKKGD-RAVRENKRIAILPDGSLRILNASKSD-EGKYVCRGENVFG---- 484
Query: 225 QKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWY--- 281
+ +++ + V E T + P+ T + G ++L C A + D+ +Y
Sbjct: 485 -----SAEIIASLSVKEPTRIELTPKRTE----LTVGESIVLNCKAIHDASLDVTFYWTL 535
Query: 282 --------KKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRV 333
++GG S +A+ + + L I N+ +G Y C S+ + V
Sbjct: 536 KGQPIDFEEEGGHFESIRAQASSAD--LMIRNILLMHAGRYGCRVQTTADSVSDEAELLV 593
Query: 334 KAAP 337
+ P
Sbjct: 594 RGPP 597
Score = 43.9 bits (102), Expect = 0.001
Identities = 38/178 (21%), Positives = 76/178 (42%), Gaps = 21/178 (11%)
Query: 37 LTQPPTITKQSAKDHIVDPRDN-ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRR 95
L PT K I+ +D ++IEC+ +G+P P+ W + R + ++ R+++
Sbjct: 402 LASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDR--AVRENKRIAILPD 459
Query: 96 SGTLVIDFRSGGRPEEYEGEYQCFARNKFGTA--LSNRIRLQVSKSPLWPKENLDPVVVQ 153
+++ + EG+Y C N FG+A +++ + ++ L PK +
Sbjct: 460 GSLRILN-----ASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKR----TELT 510
Query: 154 EGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKR-------VSQGHNGDLYFSNVML 204
G + L C V F+ + +PI ++ +Q + DL N++L
Sbjct: 511 VGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILL 568
>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
Length = 1026
Score = 339 bits (870), Expect = 8e-93
Identities = 263/905 (29%), Positives = 400/905 (44%), Gaps = 68/905 (7%)
Query: 59 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQC 118
+ + CE KGNP P W N + D R S+ G+L+I+ + G YQC
Sbjct: 46 VKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVE--GSLLIN---NPNKTQDAGTYQC 100
Query: 119 FARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSS 178
A N FGT +S +LQ + + V V+ G + L C PPP W+ +
Sbjct: 101 TATNSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFN 160
Query: 179 SMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTH--TIQQKNPFTLKVLTT 236
++R G+LY + V D+ +Y+C T+ + P L+
Sbjct: 161 EYPSYQDNRRFVSQETGNLYIAKVEKSDVG-NYTCVVTNTVTNHKVLGPPTPLILRNDGV 219
Query: 237 RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFEN 296
G E +P+ ++ +G + LEC A G P P I W + G + KA+
Sbjct: 220 MGEYEPKIEVQFPETVPTA----KGATVKLECFALGNPVPTIIWRRADGKPIARKARRHK 275
Query: 297 FNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRL 356
N L I N +ED+G Y C+A N G + A P W+ + ++ +A E+
Sbjct: 276 SNGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQKINDIHVAMEENVFW 335
Query: 357 VCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGY 416
C+ANG PKPT +W+ NGEPL + ++ T+ +S +YQC N+HG
Sbjct: 336 ECKANGRPKPTYKWLKNGEPLLT---RDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGV 392
Query: 417 LLANAFVSVLDVPP---RMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNL 473
+ +NA +SV+ V P R L R L++V ++C SP P W K G+
Sbjct: 393 IFSNAELSVIAVGPDFSRTLLKRVTLVKV--GGEVVIECKPKASPKPVYTW-KKGRDILK 449
Query: 474 DGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVA 533
+ + E+G+L I + K D G YTC+ATN G A + L VKDPTR+ P
Sbjct: 450 ENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDV 509
Query: 534 RRGTTVQLECRVKHDPSLKLTVSW------LKDDEPLYIGNRMKKEDDS--LTIFGVAER 585
G ++ L C+V HD SL + +W + D R+ +D + L I + +
Sbjct: 510 TVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLK 569
Query: 586 DQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVR 645
G Y C+ T +D+ A A L V +G P P + + ++ + + +
Sbjct: 570 HAGKYVCMVQTSVDRLSAAADLIV---------------RGPPGPPEAVTIDEITDTTAQ 614
Query: 646 LTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVN-----SAVLRLSPYVNYQF 700
L+W PG N+SPIT YV+Q F G W S P ++ + V+ L+P+V Y+F
Sbjct: 615 LSWRPGPDNHSPITMYVIQ-ARTPFSVG-WQAVSTVPELIDGKTFTATVVGLNPWVEYEF 672
Query: 701 RVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPN 760
R +A N +G PS PSE+ RT A PE P +V G G K+ + ITW + G
Sbjct: 673 RTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRG 732
Query: 761 LRYIVKWRRRETREAWNNVTVW----GSRYVVGQTPV--YVPYEIRVQAENDFGKGPEPE 814
Y+V + R + W +TV SRYV V + P+E++V N+ G+GP
Sbjct: 733 FGYVVAF-RPYGKMIW-MLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSP 790
Query: 815 SVIGYSGEDLPS-APRRFRVRQPNLETINLEWDHP-EHPNGIMIGYTLKYVAFNGTKVGK 872
+ + YS E+ P+ P R + I + W P E G + GY +KY +
Sbjct: 791 TTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENA 850
Query: 873 QIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAPPTL 932
+ + NQT + Y + A G+G S A N T PP+
Sbjct: 851 RKIRTVG-NQTSTKITNLKGSVLYHLAVKAYNSAGTG-----PSSATVN-VTTRKPPPSQ 903
Query: 933 PPTTV 937
PP +
Sbjct: 904 PPGNI 908
Score = 80.5 bits (197), Expect = 9e-15
Identities = 166/742 (22%), Positives = 264/742 (35%), Gaps = 95/742 (12%)
Query: 148 DPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDM 207
+ V +GA + L+C G P P I W + +PI + R + NG L N +D
Sbjct: 233 ETVPTAKGATVKLECFAL-GNPVPTIIWRRADGKPIARKARRHKS-NGILEIPNFQQEDA 290
Query: 208 QTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMD--LL 265
Y C A + KN RG + + P + M+ +
Sbjct: 291 GL-YECVAE-----NSRGKN-------VARG---QLTFYAQPNWIQKINDIHVAMEENVF 334
Query: 266 LECIASGVPTPDIAWYKKGGDLPS-DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGS 324
EC A+G P P W K G L + D+ + E L IT V+ D+G Y CLA NK G
Sbjct: 335 WECKANGRPKPTYKWLKNGEPLLTRDRIQIEQ--GTLNITIVNLSDAGMYQCLAENKHGV 392
Query: 325 IRHTISVRVKAAPYWLDEP---KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAP 381
I + V A + ++ G + + C+ +PKP W G +
Sbjct: 393 IFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWK-KGRDILKEN 451
Query: 382 PNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIR 441
G+ I T+ S Y C +N G + + V D P R++ P + +
Sbjct: 452 ERITISEDGNLRIINVTK-SDAGSYTCIATNHFGTASSTGNLVVKD-PTRVMVPPSSM-D 508
Query: 442 VILYNRTRLDCPFFG--SPIPTLRWFKNGQGSNLDGGNYHVYE------NGSLEIKMIRK 493
V + L C S W NG + D H G L I+ I+
Sbjct: 509 VTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQL 568
Query: 494 EDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE----DQVARRGTTVQLECRVKHDP 549
+ G Y C+ + + L V+ P PE D++ TT QL R D
Sbjct: 569 KHAGKYVCMVQTSVDRLSAAADLIVRGPPG---PPEAVTIDEIT--DTTAQLSWRPGPDN 623
Query: 550 SLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
+T+ ++ P +G + + V E G L+ + + TV
Sbjct: 624 HSPITMYVIQARTPFSVGWQ--------AVSTVPELIDGKTFTATVVGLNPWVEYEFRTV 675
Query: 610 LADQATPTNRLAALPKGRPDRPRDLELTDLAERSVR---------------LTW--IPGD 652
A+ + G P RP + T+ A V +TW +P +
Sbjct: 676 AAN---------VIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEE 726
Query: 653 ANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLR---LSPYVNYQFRVIAINEVG 709
N YVV F + +W + V R + P+ ++ +V N G
Sbjct: 727 LQNGRGFGYVVAFRP--YGKMIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKG 784
Query: 710 SSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITW-TPM--NATSAFGPNLRYIVK 766
P P+ ++ P P + ++E+ W +P+ N G ++Y
Sbjct: 785 EG-PFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKY--- 840
Query: 767 WRRRETREAWNNVTVWGSRYVVGQTPVY--VPYEIRVQAENDFGKGPEPESVIGYSGEDL 824
WR + E + G++ T + V Y + V+A N G GP +V + +
Sbjct: 841 WRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPP 900
Query: 825 PSAPRRFRVRQPNLETINLEWD 846
PS P + + I L WD
Sbjct: 901 PSQPPGNIIWNSSDSKIILNWD 922
Score = 70.9 bits (172), Expect = 7e-12
Identities = 73/307 (23%), Positives = 120/307 (39%), Gaps = 44/307 (14%)
Query: 46 QSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRS 105
Q D V +N+ EC+A G P P++ W +N + R+ + + + + I S
Sbjct: 320 QKINDIHVAMEENVFWECKANGRPKPTYKWLKNGE--PLLTRDRIQIEQGTLNITIVNLS 377
Query: 106 GGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPV-VVQEGAPLTLQCNP 164
G YQC A NK G SN ++ P + + L V +V+ G + ++C P
Sbjct: 378 DA------GMYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKP 431
Query: 165 PPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQ 224
P PV W + + +++R++ +G+L NV D + Y+C A HF
Sbjct: 432 KAS-PKPVYTW-KKGRDILKENERITISEDGNLRIINVTKSDAGS-YTCIATNHF----- 483
Query: 225 QKNPFTLKVLTTRGVAERTPSFMYPQGT-----ASSQMVLRGMDLLLECIASGVPTPDI- 278
G A T + + T SS V G ++L C + + DI
Sbjct: 484 -------------GTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIV 530
Query: 279 -AWYKKGG--DLPSDKAKFENFNKA-----LRITNVSEEDSGEYFCLASNKMGSIRHTIS 330
W G D D FE L I N+ + +G+Y C+ + +
Sbjct: 531 FTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAAD 590
Query: 331 VRVKAAP 337
+ V+ P
Sbjct: 591 LIVRGPP 597
Score = 58.5 bits (140), Expect = 4e-08
Identities = 48/157 (30%), Positives = 75/157 (47%), Gaps = 12/157 (7%)
Query: 447 RTRLDCPFFGSPIPTLRWFKNGQGSNLDGG---NYHVYENGSLEIKMIRKEDQGIYTCVA 503
+ +L+C G+P P +RW N G+++D G Y V E L + +D G Y C A
Sbjct: 45 KVKLNCEVKGNPKPHIRWKLN--GTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQCTA 102
Query: 504 TNILG---KAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 560
TN G E +++ D + R RRG + L C S +L+ +W+ +
Sbjct: 103 TNSFGTIVSREAKLQFAYLDNFKT-RTRSTVSVRRGQGMVLLCG-PPPHSGELSYAWIFN 160
Query: 561 DEPLYIGNR--MKKEDDSLTIFGVAERDQGSYTCVAS 595
+ P Y NR + +E +L I V + D G+YTCV +
Sbjct: 161 EYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVT 197
>gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
Length = 1018
Score = 337 bits (864), Expect = 4e-92
Identities = 275/932 (29%), Positives = 411/932 (44%), Gaps = 88/932 (9%)
Query: 59 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYE--GEY 116
+ + C A+ +P P + W N+ ++ D R SM G LVI+ P++ + G Y
Sbjct: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSD-RYSMV--GGNLVIN-----NPDKQKDAGIY 112
Query: 117 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF-W 175
C A N +G S L +P E V V+EG + L C+PP P + + W
Sbjct: 113 YCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRW 172
Query: 176 MSSSMEP-ITQDKR--VSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLK 232
+ + IT DKR VSQ NG+LY +NV D + +YSC F + K
Sbjct: 173 LLNEFPVFITMDKRRFVSQT-NGNLYIANVEASD-KGNYSC-----FVSSPSITKSVFSK 225
Query: 233 VLTTRGVAERTPSFMYPQGTA---SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS 289
+ + ERT YP L G ++ LEC A G P PDI W K +PS
Sbjct: 226 FIPLIPIPERTTK-PYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPS 284
Query: 290 DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA 349
A+ L+I N+ ED G Y C A N G +H + V+A P W++ + +
Sbjct: 285 T-AEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVD 343
Query: 350 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN 409
G D C A G P PT++W+ NG G+ ++ D + +YQC
Sbjct: 344 IGSDLYWPCVATGKPIPTIRWLKNGYAYHK----------GELRLY-DVTFENAGMYQCI 392
Query: 410 TSNEHGYLLANAFVSVLDVPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG 468
N +G + ANA + +L + P ++P + I R ++C +P P W K G
Sbjct: 393 AENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK-G 451
Query: 469 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMP 528
++ ++E+GSLEI I + D GIYTC A N GKA + L + DPTRI P
Sbjct: 452 TEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAP 511
Query: 529 EDQVARRGTTVQLECRVKHDPSLKLTVSW--------LKDDEPLYIGNRMKKEDDSLTIF 580
+ G ++C DP+L LT W + Y N M + L I
Sbjct: 512 INADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIR 571
Query: 581 GVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLA 640
+ G YTC A T +D A A L V +G P P L + D+
Sbjct: 572 NAQLKHAGRYTCTAQTIVDNSSASADLVV---------------RGPPGPPGGLRIEDIR 616
Query: 641 ERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP----GSVNSA-VLRLSPY 695
SV LTW G N+SPI+ Y +Q + W D P G++ +A + L P+
Sbjct: 617 ATSVALTWSRGSDNHSPISKYTIQTKT--ILSDDWKDAKTDPPIIEGNMEAARAVDLIPW 674
Query: 696 VNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATS 755
+ Y+FRV+A N +G PS+PS R +T GA P P DV G G R + ITW P++
Sbjct: 675 MEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREY 734
Query: 756 AFGPNLRYIVKWRRRETREAWNNVTVWG---SRYVVGQTPV--YVPYEIRVQAENDFGKG 810
+G N YIV ++ + E W VTV RYV + ++++V+A N+ G G
Sbjct: 735 HYGNNFGYIVAFKPFDGEE-WKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDG 793
Query: 811 PEPESVIGYSGEDLPS-APRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTK 869
P + S +D PS AP V+ + I++ W+H I+ Y ++Y A + +
Sbjct: 794 PYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEK--IVESYQIRYWAAHDKE 851
Query: 870 VGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAP 929
V+ + + ++ P ++Y + A G G P+ EA AP
Sbjct: 852 EAANRVQ-VTSQEYSARLENLLPDTQYFIEVGACNSAGCG------PPSDMIEAFTKKAP 904
Query: 930 PTLPPTTVGATGAVSSTDAT---AIAATTEAT 958
P+ PP + + + S T +A + E+T
Sbjct: 905 PSQPPRIISSVRSGSRYIITWDHVVALSNEST 936
Score = 76.3 bits (186), Expect = 2e-13
Identities = 89/383 (23%), Positives = 141/383 (36%), Gaps = 46/383 (12%)
Query: 40 PPTITKQSAKDHIVDPRD-------NILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSM 92
P TK D +V +D N+ +EC A GNP P W + + P +
Sbjct: 233 PERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK-----VLEPMPSTAE 287
Query: 93 RRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVV 152
SG ++ F E EG Y+C A N G ++ R+ V P W E+++ V
Sbjct: 288 ISTSGAVLKIFNI---QLEDEGIYECEAENIRGKD-KHQARIYVQAFPEW-VEHINDTEV 342
Query: 153 QEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYS 212
G+ L C G P P I W+ K H G+L +V ++ Y
Sbjct: 343 DIGSDLYWPC-VATGKPIPTIRWL----------KNGYAYHKGELRLYDVTFENAGM-YQ 390
Query: 213 CNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASG 272
C A + LK+L E P + +G +++EC
Sbjct: 391 CIAENTYGAIYANAE---LKILALAPTFEMNP-------MKKKILAAKGGRVIIECKPKA 440
Query: 273 VPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVR 332
P P +W K L + + +L I N++ D G Y C A N G T ++
Sbjct: 441 APKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLV 500
Query: 333 VKAAPYWLDEPKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPLQSAPPNPNRE--- 387
+ + P N + GE+ + C A+ +P T W NG + N + +
Sbjct: 501 ITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNF 560
Query: 388 --VAGDTIIFRDTQISSRAVYQC 408
+ ++ R+ Q+ Y C
Sbjct: 561 MLDSNGELLIRNAQLKHAGRYTC 583
Score = 50.8 bits (120), Expect = 8e-06
Identities = 40/160 (25%), Positives = 69/160 (43%), Gaps = 8/160 (5%)
Query: 444 LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 503
L + L+C SP P +W N +L Y + + +++D GIY C+A
Sbjct: 57 LEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLA 116
Query: 504 TNILG---KAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 560
+N G E + DP PE +V + G + L C + L+ WL +
Sbjct: 117 SNNYGMVRSTEATLSFGYLDPFPPEERPEVRV-KEGKGMVLLCDPPYHFPDDLSYRWLLN 175
Query: 561 DEPLYI----GNRMKKEDDSLTIFGVAERDQGSYTCVAST 596
+ P++I + + + +L I V D+G+Y+C S+
Sbjct: 176 EFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
>gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]
Length = 1007
Score = 337 bits (864), Expect = 4e-92
Identities = 275/932 (29%), Positives = 411/932 (44%), Gaps = 88/932 (9%)
Query: 59 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYE--GEY 116
+ + C A+ +P P + W N+ ++ D R SM G LVI+ P++ + G Y
Sbjct: 50 VSLNCRARASPFPVYKWRMNNGDVDLTSD-RYSMV--GGNLVIN-----NPDKQKDAGIY 101
Query: 117 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF-W 175
C A N +G S L +P E V V+EG + L C+PP P + + W
Sbjct: 102 YCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRW 161
Query: 176 MSSSMEP-ITQDKR--VSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLK 232
+ + IT DKR VSQ NG+LY +NV D + +YSC F + K
Sbjct: 162 LLNEFPVFITMDKRRFVSQT-NGNLYIANVEASD-KGNYSC-----FVSSPSITKSVFSK 214
Query: 233 VLTTRGVAERTPSFMYPQGTA---SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS 289
+ + ERT YP L G ++ LEC A G P PDI W K +PS
Sbjct: 215 FIPLIPIPERTTK-PYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPS 273
Query: 290 DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA 349
A+ L+I N+ ED G Y C A N G +H + V+A P W++ + +
Sbjct: 274 T-AEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVD 332
Query: 350 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN 409
G D C A G P PT++W+ NG G+ ++ D + +YQC
Sbjct: 333 IGSDLYWPCVATGKPIPTIRWLKNGYAYHK----------GELRLY-DVTFENAGMYQCI 381
Query: 410 TSNEHGYLLANAFVSVLDVPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG 468
N +G + ANA + +L + P ++P + I R ++C +P P W K G
Sbjct: 382 AENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK-G 440
Query: 469 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMP 528
++ ++E+GSLEI I + D GIYTC A N GKA + L + DPTRI P
Sbjct: 441 TEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAP 500
Query: 529 EDQVARRGTTVQLECRVKHDPSLKLTVSW--------LKDDEPLYIGNRMKKEDDSLTIF 580
+ G ++C DP+L LT W + Y N M + L I
Sbjct: 501 INADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIR 560
Query: 581 GVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLA 640
+ G YTC A T +D A A L V +G P P L + D+
Sbjct: 561 NAQLKHAGRYTCTAQTIVDNSSASADLVV---------------RGPPGPPGGLRIEDIR 605
Query: 641 ERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP----GSVNSA-VLRLSPY 695
SV LTW G N+SPI+ Y +Q + W D P G++ +A + L P+
Sbjct: 606 ATSVALTWSRGSDNHSPISKYTIQTKT--ILSDDWKDAKTDPPIIEGNMEAARAVDLIPW 663
Query: 696 VNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATS 755
+ Y+FRV+A N +G PS+PS R +T GA P P DV G G R + ITW P++
Sbjct: 664 MEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREY 723
Query: 756 AFGPNLRYIVKWRRRETREAWNNVTVWG---SRYVVGQTPV--YVPYEIRVQAENDFGKG 810
+G N YIV ++ + E W VTV RYV + ++++V+A N+ G G
Sbjct: 724 HYGNNFGYIVAFKPFDGEE-WKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDG 782
Query: 811 PEPESVIGYSGEDLPS-APRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTK 869
P + S +D PS AP V+ + I++ W+H I+ Y ++Y A + +
Sbjct: 783 PYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEK--IVESYQIRYWAAHDKE 840
Query: 870 VGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAP 929
V+ + + ++ P ++Y + A G G P+ EA AP
Sbjct: 841 EAANRVQ-VTSQEYSARLENLLPDTQYFIEVGACNSAGCG------PPSDMIEAFTKKAP 893
Query: 930 PTLPPTTVGATGAVSSTDAT---AIAATTEAT 958
P+ PP + + + S T +A + E+T
Sbjct: 894 PSQPPRIISSVRSGSRYIITWDHVVALSNEST 925
Score = 76.3 bits (186), Expect = 2e-13
Identities = 89/383 (23%), Positives = 141/383 (36%), Gaps = 46/383 (12%)
Query: 40 PPTITKQSAKDHIVDPRD-------NILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSM 92
P TK D +V +D N+ +EC A GNP P W + + P +
Sbjct: 222 PERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK-----VLEPMPSTAE 276
Query: 93 RRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVV 152
SG ++ F E EG Y+C A N G ++ R+ V P W E+++ V
Sbjct: 277 ISTSGAVLKIFNI---QLEDEGIYECEAENIRGKD-KHQARIYVQAFPEW-VEHINDTEV 331
Query: 153 QEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYS 212
G+ L C G P P I W+ K H G+L +V ++ Y
Sbjct: 332 DIGSDLYWPC-VATGKPIPTIRWL----------KNGYAYHKGELRLYDVTFENAGM-YQ 379
Query: 213 CNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASG 272
C A + LK+L E P + +G +++EC
Sbjct: 380 CIAENTYGAIYANAE---LKILALAPTFEMNP-------MKKKILAAKGGRVIIECKPKA 429
Query: 273 VPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVR 332
P P +W K L + + +L I N++ D G Y C A N G T ++
Sbjct: 430 APKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLV 489
Query: 333 VKAAPYWLDEPKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPLQSAPPNPNRE--- 387
+ + P N + GE+ + C A+ +P T W NG + N + +
Sbjct: 490 ITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNF 549
Query: 388 --VAGDTIIFRDTQISSRAVYQC 408
+ ++ R+ Q+ Y C
Sbjct: 550 MLDSNGELLIRNAQLKHAGRYTC 572
Score = 50.8 bits (120), Expect = 8e-06
Identities = 40/160 (25%), Positives = 69/160 (43%), Gaps = 8/160 (5%)
Query: 444 LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 503
L + L+C SP P +W N +L Y + + +++D GIY C+A
Sbjct: 46 LEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLA 105
Query: 504 TNILG---KAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 560
+N G E + DP PE +V + G + L C + L+ WL +
Sbjct: 106 SNNYGMVRSTEATLSFGYLDPFPPEERPEVRV-KEGKGMVLLCDPPYHFPDDLSYRWLLN 164
Query: 561 DEPLYI----GNRMKKEDDSLTIFGVAERDQGSYTCVAST 596
+ P++I + + + +L I V D+G+Y+C S+
Sbjct: 165 EFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSS 204
>gi|75709184 contactin 3 [Homo sapiens]
Length = 1028
Score = 330 bits (846), Expect = 5e-90
Identities = 261/968 (26%), Positives = 415/968 (42%), Gaps = 99/968 (10%)
Query: 8 PWVHAAFLLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHI-VDPRDN-ILIECEA 65
PW L + LGG + L Q P K+ + V D I + CEA
Sbjct: 4 PWKQLILLSFIGCLGGEL-----------LLQGPVFIKEPSNSIFPVGSEDKKITLHCEA 52
Query: 66 KGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFG 125
+GNP+P + W N +++ + R + G LV+ G YQCFA N G
Sbjct: 53 RGNPSPHYRWQLNGSDIDMSMEHRYKLN--GGNLVV---INPNRNWDTGTYQCFATNSLG 107
Query: 126 TALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQ 185
T +S +LQ + + + V V+EG + L C PPP W+ + +
Sbjct: 108 TIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVE 167
Query: 186 D--KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHT--IQQKNPFTLKVLTTRGVAE 241
+ +R G LY S V D+ +Y+C T+ + P L+ G E
Sbjct: 168 EDSRRFVSQETGHLYISKVEPSDVG-NYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYE 226
Query: 242 RTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKAL 301
+P+ ++ +G + LEC A G P P I W + G S K K F+ L
Sbjct: 227 PKIEVQFPETLPAA----KGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVL 282
Query: 302 RITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRAN 361
I N +ED+G Y C+A N G + A P+W+ K++ +A + CRA+
Sbjct: 283 EIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRAS 342
Query: 362 GNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANA 421
G PKP+ +W+ NG L ++ + + ++ ++QC N+HG + ++A
Sbjct: 343 GKPKPSYRWLKNGAALVL---EERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSA 399
Query: 422 FVSVL-DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHV 480
+ V+ P +P +L++V + + LDC SP W K G S + +
Sbjct: 400 ELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSW-KKGDVSVQEHERISL 458
Query: 481 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 540
+G L+I + K D G YTC+A N GKA L V +PTRI P + G +V
Sbjct: 459 LNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVI 518
Query: 541 LECRVKHDPSLKLTVSW--------LKDDEPLYIGNRMKKEDDS----LTIFGVAERDQG 588
L C+V+HDP L + +W K D G+ +K S L I + + G
Sbjct: 519 LPCQVQHDPLLDIIFTWYFNGALADFKKD-----GSHFEKVGGSSSGDLMIRNIQLKHSG 573
Query: 589 SYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTW 648
Y C+ T +D + A L V +G P P ++++ ++ + + +L+W
Sbjct: 574 KYVCMVQTGVDSVSSAADLIV---------------RGSPGPPENVKVDEITDTTAQLSW 618
Query: 649 IPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVN-----SAVLRLSPYVNYQFRVI 703
G N+SP+ Y +Q F G W + P ++ + V+ L+P+V Y+FRV+
Sbjct: 619 KEGKDNHSPVISYSIQ-ARTPFSVG-WQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVV 676
Query: 704 AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY 763
A N++G PSLPSE+ RT A PE P +V G G ++ + ITW P+ G Y
Sbjct: 677 ASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGY 736
Query: 764 IVKWRRRETREAWNNVTVWGSRYVVG-QTPVYV----------PYEIRVQAENDFGKGPE 812
+V +R VT W V TP YV PYE++V N+ G+GP
Sbjct: 737 VVAFRPL-------GVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPF 789
Query: 813 PESVIGYSGEDLPS-APRRFRVRQPNLETINLEWDHP--EHPNGIMIGYTLKYVAFNGTK 869
+S E+ P+ AP + + I + W+ + NG ++GY ++Y G +
Sbjct: 790 SPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKE 849
Query: 870 VGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAP 929
++ + N+T ++ Y + A G+G + T P
Sbjct: 850 ESSSKMK-VAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPF------SATVNVTTKKTP 902
Query: 930 PTLPPTTV 937
P+ PP V
Sbjct: 903 PSQPPGNV 910
>gi|7657361 contactin 6 [Homo sapiens]
Length = 1028
Score = 298 bits (762), Expect = 3e-80
Identities = 246/909 (27%), Positives = 391/909 (43%), Gaps = 68/909 (7%)
Query: 56 RDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 115
+ +++ C A G P+P + W +N + R G+L I+ ++ G
Sbjct: 43 KSEVILNCAANGYPSPHYRWKQNGTDIDFTMS--YHYRLDGGSLAIN---SPHTDQDIGM 97
Query: 116 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 175
YQC A N GT LS + +LQ + + + V V+EG + L C PPP W
Sbjct: 98 YQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAW 157
Query: 176 MSSSMEPITQD--KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKV 233
+ Q+ +R G+LY + V D+ +Y+C Q P L
Sbjct: 158 TFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVG-NYTCFITNKEAQRSVQGPPTPLVQ 216
Query: 234 LTTRGVAERTPSF--MYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDK 291
T + E P +P+ ++ + + LEC A G P PDI+W + G K
Sbjct: 217 RTDGVMGEYEPKIEVRFPETIQAA----KDSSVKLECFALGNPVPDISWRRLDGSPLPGK 272
Query: 292 AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPG 351
K+ L I N +ED G Y C+ASN G + A P W + +N L+
Sbjct: 273 VKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIY 332
Query: 352 EDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTS 411
++ C+A+G P P W+ NGE L P ++ T+I +S VYQC
Sbjct: 333 DNLLWECKASGKPNPWYTWLKNGERLN---PEERIQIENGTLIITMLNVSDSGVYQCAAE 389
Query: 412 NEHGYLLANAFVSVL-DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG 470
N++ + ANA + VL P SP + V + + C P + W K G
Sbjct: 390 NKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISW-KRGTE 448
Query: 471 SNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPED 530
+ + E+GSL+I I + D G YTC+ATN G A+N L VK+ T I P
Sbjct: 449 TLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSK 508
Query: 531 QVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-------KEDDSLTIFGVA 583
G ++ L C+V HDPS+++ W + + + + + + L I +
Sbjct: 509 MDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQ 568
Query: 584 ERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERS 643
G Y C T L+ L+ +AD + +G P P D+++ D++ +
Sbjct: 569 LHHSGKYLCTVQTTLES------LSAVAD---------IIVRGPPGPPEDVQVEDISSTT 613
Query: 644 VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP-----GSVNSAVLRLSPYVNY 698
+L+W G NNSPI + +Q F G W + P + N+ V+ LSP+V Y
Sbjct: 614 SQLSWRAGPDNNSPIQIFTIQ-TRTPFSVG-WQAVATVPEILNGKTYNATVVGLSPWVEY 671
Query: 699 QFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFG 758
+FRV+A N +G PS PSE RT + P P ++ G G ++ + ITW + G
Sbjct: 672 EFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNG 731
Query: 759 PNLRYIVKWRRRETREAWNN---VTVWGSRYVVGQTPV--YVPYEIRVQAENDFGKGPEP 813
YI+ +R + W+ +V SR+V + P+E++V N+ G+G
Sbjct: 732 EGFGYIIMFRPVGS-TTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLS 790
Query: 814 ESVIGYSGEDLPS-APRRFRVRQPNLETINLEWDHP--EHPNGIMIGYTLKYVAFNG--T 868
I YSGED P APR ++ + + + W+ G ++GY + Y + +
Sbjct: 791 TVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKES 850
Query: 869 KVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAA 928
+GK V S N T + + Y ++ A G+G + +PP T +
Sbjct: 851 MIGKIRV---SGNVTTKNITGLKANTIYFASVRAYNTAGTGPS------SPPVNVTTKKS 901
Query: 929 PPTLPPTTV 937
PP+ PP +
Sbjct: 902 PPSQPPANI 910
Score = 108 bits (271), Expect = 2e-23
Identities = 172/779 (22%), Positives = 281/779 (36%), Gaps = 82/779 (10%)
Query: 301 LRITNVSEEDSGEYFCLASNKMGS----------IRHTISVRVKAAP-YWLDEPKNLILA 349
L I V D G Y C +NK ++ T V + P + P+ + A
Sbjct: 181 LYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAA 240
Query: 350 PGEDGRLVCRANGNPKPTVQWM-VNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQC 408
+L C A GNP P + W ++G PL P + + + Q Y+C
Sbjct: 241 KDSSVKLECFALGNPVPDISWRRLDGSPL---PGKVKYSKSQAILEIPNFQQEDEGFYEC 297
Query: 409 NTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG 468
SN G LA + + PP + Q + +Y+ +C G P P W KNG
Sbjct: 298 IASNLRGRNLAKGQL-IFYAPPEW-EQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNG 355
Query: 469 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN----ILGKAENQVRLEVKDPTRI 524
+ N + ENG+L I M+ D G+Y C A N I AE +V D ++
Sbjct: 356 ERLNPE--ERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKS 413
Query: 525 YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRM-KKEDDSLTIFGVA 583
+ + + G + + C+ P + +SW + E L R+ ED SL I+ +
Sbjct: 414 -PVKKKSFVQVGGDIVIGCKPNAFP--RAAISWKRGTETLRQSKRIFLLEDGSLKIYNIT 470
Query: 584 ERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERS 643
D GSYTC+A+ + AK +++ + T + +P + D + E
Sbjct: 471 RSDAGSYTCIATNQFGT--AKNTGSLIVKERT----VITVPPSKMD-------VTVGESI 517
Query: 644 VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVI 703
V + D + + + + + GV H SV ++R + +
Sbjct: 518 VLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLC 577
Query: 704 AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWT--PMNATS----AF 757
+ S ++ R PPE DV+ E +++W P N +
Sbjct: 578 TVQTTLESLSAVADIIVRGPPGPPE----DVQVEDISSTTSQLSWRAGPDNNSPIQIFTI 633
Query: 758 GPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGP--EPES 815
+ V W+ T N + + VVG +P +V YE RV A N G G EP
Sbjct: 634 QTRTPFSVGWQAVATVPEILNGKTYNAT-VVGLSP-WVEYEFRVVAGNSIGIGEPSEPSE 691
Query: 816 VIGYSGEDLPSAPRRFRVRQPNLETINLEWDH--PEHPNGIMIGYTLKYVAFNGTKVGKQ 873
++ AP + + + W+ E NG GY + + T K+
Sbjct: 692 LLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKE 751
Query: 874 IVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAPPTLP 933
V + ++ + + P+S + + G G T + E P AP
Sbjct: 752 KVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTV-TIVYSGEDEPQLAPRGTS 810
Query: 934 PTTVGATGAVSSTDATA------------IAATTEATTVPIIPTVAPTTIATTTTVATTT 981
+ A+ S +A A + T+ + +I + + TT +
Sbjct: 811 LQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKNITGLK 870
Query: 982 TTTA---------AATTTTESPPTTTSGTKIHESAPDEQSIWNVTVLPNSKWANITWKH 1031
T A T SPP + K S P W +T NSK + W+H
Sbjct: 871 ANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLT---NSKLC-LNWEH 925
>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
Length = 698
Score = 238 bits (606), Expect = 3e-62
Identities = 183/604 (30%), Positives = 275/604 (45%), Gaps = 56/604 (9%)
Query: 358 CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYL 417
C+ANG PKPT +W+ NGEPL + ++ T+ +S +YQC N+HG +
Sbjct: 9 CKANGRPKPTYKWLKNGEPLLT---RDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVI 65
Query: 418 LANAFVSVLDVPP---RMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLD 474
+NA +SV+ V P R L R L++V ++C SP P W K G+ +
Sbjct: 66 FSNAELSVIAVGPDFSRTLLKRVTLVKV--GGEVVIECKPKASPKPVYTW-KKGRDILKE 122
Query: 475 GGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVAR 534
+ E+G+L I + K D G YTC+ATN G A + L VKDPTR+ P
Sbjct: 123 NERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVT 182
Query: 535 RGTTVQLECRVKHDPSLKLTVSW------LKDDEPLYIGNRMKKEDDS--LTIFGVAERD 586
G ++ L C+V HD SL + +W + D R+ +D + L I + +
Sbjct: 183 VGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKH 242
Query: 587 QGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRL 646
G Y C+ T +D+ A A L V +G P P + + ++ + + +L
Sbjct: 243 AGKYVCMVQTSVDRLSAAADLIV---------------RGPPGPPEAVTIDEITDTTAQL 287
Query: 647 TWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVN-----SAVLRLSPYVNYQFR 701
+W PG N+SPIT YV+Q F G W S P ++ + V+ L+P+V Y+FR
Sbjct: 288 SWRPGPDNHSPITMYVIQ-ARTPFSVG-WQAVSTVPELIDGKTFTATVVGLNPWVEYEFR 345
Query: 702 VIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNL 761
+A N +G PS PSE+ RT A PE P +V G G K+ + ITW + G
Sbjct: 346 TVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGF 405
Query: 762 RYIVKWRRRETREAWNNVTVW----GSRYVVGQTPV--YVPYEIRVQAENDFGKGPEPES 815
Y+V + R + W +TV SRYV V + P+E++V N+ G+GP +
Sbjct: 406 GYVVAF-RPYGKMIW-MLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPT 463
Query: 816 VIGYSGEDLPS-APRRFRVRQPNLETINLEWDHP-EHPNGIMIGYTLKYVAFNGTKVGKQ 873
+ YS E+ P+ P R + I + W P E G + GY +KY + +
Sbjct: 464 TVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENAR 523
Query: 874 IVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAPPTLP 933
+ NQT + Y + A G+G S A N T PP+ P
Sbjct: 524 KIRTVG-NQTSTKITNLKGSVLYHLAVKAYNSAGTG-----PSSATVN-VTTRKPPPSQP 576
Query: 934 PTTV 937
P +
Sbjct: 577 PGNI 580
Score = 75.1 bits (183), Expect = 4e-13
Identities = 139/621 (22%), Positives = 222/621 (35%), Gaps = 75/621 (12%)
Query: 267 ECIASGVPTPDIAWYKKGGDLPS-DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSI 325
EC A+G P P W K G L + D+ + E L IT V+ D+G Y CLA NK G I
Sbjct: 8 ECKANGRPKPTYKWLKNGEPLLTRDRIQIEQ--GTLNITIVNLSDAGMYQCLAENKHGVI 65
Query: 326 RHTISVRVKAAPYWLDEP---KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPP 382
+ V A + ++ G + + C+ +PKP W G +
Sbjct: 66 FSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWK-KGRDILKENE 124
Query: 383 NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRV 442
G+ I T+ S Y C +N G + + V D P R++ P + + V
Sbjct: 125 RITISEDGNLRIINVTK-SDAGSYTCIATNHFGTASSTGNLVVKD-PTRVMVPPSSM-DV 181
Query: 443 ILYNRTRLDCPFFG--SPIPTLRWFKNGQGSNLDGGNYHVYE------NGSLEIKMIRKE 494
+ L C S W NG + D H G L I+ I+ +
Sbjct: 182 TVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLK 241
Query: 495 DQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE----DQVARRGTTVQLECRVKHDPS 550
G Y C+ + + L V+ P PE D++ TT QL R D
Sbjct: 242 HAGKYVCMVQTSVDRLSAAADLIVRGPPG---PPEAVTIDEIT--DTTAQLSWRPGPDNH 296
Query: 551 LKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVL 610
+T+ ++ P +G + + V E G L+ + + TV
Sbjct: 297 SPITMYVIQARTPFSVGWQ--------AVSTVPELIDGKTFTATVVGLNPWVEYEFRTVA 348
Query: 611 ADQATPTNRLAALPKGRPDRPRDLELTDLAERSVR---------------LTW--IPGDA 653
A+ + G P RP + T+ A V +TW +P +
Sbjct: 349 AN---------VIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEEL 399
Query: 654 NNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLR---LSPYVNYQFRVIAINEVGS 710
N YVV F + +W + V R + P+ ++ +V N G
Sbjct: 400 QNGRGFGYVVAFRP--YGKMIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGE 457
Query: 711 SHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITW-TPM--NATSAFGPNLRYIVKW 767
P P+ ++ P P + ++E+ W +P+ N G ++Y W
Sbjct: 458 G-PFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKY---W 513
Query: 768 RRRETREAWNNVTVWGSRYVVGQTPVY--VPYEIRVQAENDFGKGPEPESVIGYSGEDLP 825
R + E + G++ T + V Y + V+A N G GP +V + + P
Sbjct: 514 RHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPP 573
Query: 826 SAPRRFRVRQPNLETINLEWD 846
S P + + I L WD
Sbjct: 574 SQPPGNIIWNSSDSKIILNWD 594
Score = 69.3 bits (168), Expect = 2e-11
Identities = 70/296 (23%), Positives = 117/296 (39%), Gaps = 44/296 (14%)
Query: 57 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 116
+N+ EC+A G P P++ W +N + R+ + + + + I S G Y
Sbjct: 3 ENVFWECKANGRPKPTYKWLKNGE--PLLTRDRIQIEQGTLNITIVNLSDA------GMY 54
Query: 117 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPV-VVQEGAPLTLQCNPPPGLPSPVIFW 175
QC A NK G SN ++ P + + L V +V+ G + ++C P P PV W
Sbjct: 55 QCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKAS-PKPVYTW 113
Query: 176 MSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLT 235
+ + +++R++ +G+L NV D + Y+C A HF
Sbjct: 114 -KKGRDILKENERITISEDGNLRIINVTKSDAGS-YTCIATNHF---------------- 155
Query: 236 TRGVAERTPSFMYPQGT-----ASSQMVLRGMDLLLECIASGVPTPDI--AWYKKGG--D 286
G A T + + T SS V G ++L C + + DI W G D
Sbjct: 156 --GTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLID 213
Query: 287 LPSDKAKFENFNKA-----LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAP 337
D FE L I N+ + +G+Y C+ + + + V+ P
Sbjct: 214 FDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPP 269
Score = 55.8 bits (133), Expect = 2e-07
Identities = 69/272 (25%), Positives = 112/272 (41%), Gaps = 24/272 (8%)
Query: 167 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQK 226
G P P W+ + +T+D+ Q G L + V L D Y C A H +
Sbjct: 13 GRPKPTYKWLKNGEPLLTRDR--IQIEQGTLNITIVNLSDAGM-YQCLAENK--HGVIFS 67
Query: 227 NPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGD 286
N L V+ RT + + T +V G ++++EC P P W KKG D
Sbjct: 68 NA-ELSVIAVGPDFSRT---LLKRVT----LVKVGGEVVIECKPKASPKPVYTW-KKGRD 118
Query: 287 LPSDKAKFE-NFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKN 345
+ + + + + LRI NV++ D+G Y C+A+N G+ T ++ VK + P +
Sbjct: 119 ILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSS 178
Query: 346 LILAPGEDGRLVCRANGNPKPTV--QWMVNGEPLQSAPPNPN------REVAGDTIIFRD 397
+ + GE L C+ + + W NG + + ++ AGD +I R+
Sbjct: 179 MDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMI-RN 237
Query: 398 TQISSRAVYQCNTSNEHGYLLANAFVSVLDVP 429
Q+ Y C L A A + V P
Sbjct: 238 IQLKHAGKYVCMVQTSVDRLSAAADLIVRGPP 269
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 225 bits (573), Expect = 2e-58
Identities = 209/774 (27%), Positives = 323/774 (41%), Gaps = 58/774 (7%)
Query: 114 GEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVI 173
G Y+C RN+ G L + +QV+ + + V Q G L P P P +
Sbjct: 165 GFYRCVVRNRMGALLQRKSEVQVAYMGSFMDTDQRKTVSQ-GRAAILNLLPITSYPRPQV 223
Query: 174 FWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKN------ 227
W + I ++ N V+L +D A ++ + +KN
Sbjct: 224 TWFREGHKIIPSNRIAITLEN-----QLVILATTTSD----AGAYYVQAVNEKNGENKTS 274
Query: 228 PFT-LKVLTTRGVAER-TPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIA--WYKK 283
PF L + G E P+ + P G S +V + LECIAS P D++ W +
Sbjct: 275 PFIHLSIARDVGTPETMAPTIVVPPGNRS--VVAGSSETTLECIASARPVEDLSVTWKRN 332
Query: 284 GGDLPSDKAKFENFNKALRITNVSEEDSGEYFC---LASNKMGSIRHTISVRVKAAPYWL 340
G + S +F + L I+N + D+G Y C L + R T + + PY+
Sbjct: 333 GVRITSG---LHSFGRRLTISNPTSADTGPYVCEAALPGSAFEPARATAFLFIIEPPYFT 389
Query: 341 DEPKNLILAPGEDG-RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV-AGDTIIFRDT 398
EP++ I A E+ + C+A G P PT+QW + + S NP +V A + +
Sbjct: 390 AEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISI-SRLQNPRYKVLASGGLRIQKL 448
Query: 399 QISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSP 458
+ ++QC SNE G + + ++ V ++ P + + R V L C G+P
Sbjct: 449 RPEDSGIFQCFASNEGGEIQTHTYLDVTNIAP-VFTQRPVDTTVTDGMTAILRCEVSGAP 507
Query: 459 IPTLRWFKNGQ---GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR 515
P + W + ++ + + E+G L+I + +D G YTC A N G
Sbjct: 508 KPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASAT 567
Query: 516 LEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDD---EPLYIGNRMKK 572
L V + T I PED V +GTT L C HDP + L W KD+ P + +
Sbjct: 568 LTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLRYVWKKDNVALTPSSTSRIVVE 627
Query: 573 EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPR 632
+D SL I D G Y+C +E D A L V+ +P N L +
Sbjct: 628 KDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELPHSPQNLLVSPNSSH----- 682
Query: 633 DLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRL 692
+V L+W+ NSPI Y+V+ E+ P H + P V L
Sbjct: 683 --------SHAVVLSWVRPFDGNSPILYYIVELSENN-SPWKVHLSNVGPEMTGVTVSGL 733
Query: 693 SPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMN 752
+P YQFRV A+NEVG S + R PP + P ++ G ++ + W P
Sbjct: 734 TPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPP 793
Query: 753 ATSAFGPNLRYIVKWRRRETREAW--NNVTVWGSRY-VVGQTPVYVPYEIRVQAENDFGK 809
T G YI+++R + N+T Y +V ++ YEI+V A N G
Sbjct: 794 ETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGL 853
Query: 810 GPEPESVIGYSGEDLPSA-PRRFRVRQPNLETINLEWDHP--EHPNGIMIGYTL 860
G +V Y+ + +P+A P+ + N TI W+ P + NGI GY L
Sbjct: 854 GVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKL 907
Score = 97.1 bits (240), Expect = 1e-19
Identities = 128/572 (22%), Positives = 215/572 (37%), Gaps = 68/572 (11%)
Query: 627 RPDRPRDLEL--TDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGS 684
RP PR+L + ++ RS+RL W+PG SPI + +Q E G W +S
Sbjct: 1476 RPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRE--LPRGEWQTYSSSISH 1533
Query: 685 VNSAVL--RLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKN 742
+A + RL P+ +Y+ R+ A N++G S S +E T P PG V +
Sbjct: 1534 EATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTS 1593
Query: 743 NMEITWTPMNATSAFGPNLRYIVKWRRRETREAWN--------------NVTVWGSRYVV 788
++ I W P S G Y + +R E +T S V
Sbjct: 1594 SVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTV 1653
Query: 789 GQTPV-----------YVPYEIRVQAENDFGKGPEPESVIGYSGEDLPS-APRRFRVRQP 836
+ Y YE+ + A N G+ P V + GE P+ AP+ +V
Sbjct: 1654 NSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPL 1713
Query: 837 NLETINLEWD--HPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVS 894
+ + WD PE NG + GY + Y + +++ F P + ++ +
Sbjct: 1714 TASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLP-EPVVRLKNLTSHT 1772
Query: 895 RYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAPPTLPPTTVGATGAVSS----TDATA 950
+Y ++SA G G ++ ++A P AP L + + +T S A
Sbjct: 1773 KYLVSISAFNAAGDGPK-SDPQQGRTHQAAP-GAPSFLAFSEITSTTLNVSWGEPAAANG 1830
Query: 951 IAATTEATTVPIIPTVAPTTIATT--------------TTVATTTTTTAAATTTTESPPT 996
I P+ P + + T T T A T T P
Sbjct: 1831 ILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYGPEL 1890
Query: 997 TTSGTK-IHESAPDEQSIWNVTVLPNSKWANITWKHNFG---PGTDFVVEYIDSNH---- 1048
+ T E +P S +V V ++ + W P T +V+E S+
Sbjct: 1891 QANITAGPAEGSPG--SPRDVLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWD 1948
Query: 1049 -TKKTVPVKAQAQPIQLTDLYPGMTYTLRVYSRDNEGISSTVITFMTSTAYTNNQADIAT 1107
K +P A + + L L G+TY RV + + G + ++ +A
Sbjct: 1949 MFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEP--SNPSTAVSAQVEAPFYE 2006
Query: 1108 QGWFIGLMCAIALLVLILLIVCFIKRSRGGKY 1139
+ WF+ +M +L+V++L++ + + KY
Sbjct: 2007 EWWFLLVMALSSLIVILLVVFALVLHGQNKKY 2038
Score = 94.4 bits (233), Expect = 6e-19
Identities = 82/325 (25%), Positives = 138/325 (42%), Gaps = 19/325 (5%)
Query: 615 TPTNRLAALPKGRPD-RPRDLELTDLAERSVRLTWIP---GDANNSPIT-DYVVQFEEDQ 669
+P++R+ + PD P + + +E S+RL W+P N +P + Y +++
Sbjct: 1160 SPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSD 1219
Query: 670 FQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPES 729
Q + L ++ Y+ ++ A N VG+ P R RT + P +
Sbjct: 1220 LQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAVGAG-PWSEVVRGRTRESVPSA 1278
Query: 730 NPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRY--- 786
P +V E + +TWT + G L Y + +R ++ + V G+
Sbjct: 1279 APENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSA 1338
Query: 787 VVGQTPVYVPYEIRVQAENDFGKG-PEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEW 845
++ +V YE++V A G G P ++ + +D P P R + L ++ + W
Sbjct: 1339 LLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVW 1398
Query: 846 DHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQ 905
PE PNGI++GY + Y + + VE +FT P S Y F LSA+T+
Sbjct: 1399 QPPEEPNGIILGYQIAYRLASSSPHTFTTVE-VGATVRQFTATDLAPESAYIFRLSAKTR 1457
Query: 906 VGSGEAV--------TEESPAPPNE 922
G GE + E PAPP E
Sbjct: 1458 QGWGEPLEATVITTEKRERPAPPRE 1482
Score = 92.4 bits (228), Expect = 2e-18
Identities = 202/993 (20%), Positives = 374/993 (37%), Gaps = 130/993 (13%)
Query: 16 LCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHW 75
+C +L G+ P + + +PP T + + + + I C+A G P P+ W
Sbjct: 361 VCEAALPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQW 420
Query: 76 TRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQ 135
+++ + ++PR + G + RPE+ G +QCFA N+ G ++
Sbjct: 421 YKDAISISRLQNPRYKVLASGGLRIQKL----RPED-SGIFQCFASNEGGEIQTHTYLDV 475
Query: 136 VSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQG--- 192
+ +P++ + +D V +G L+C G P P I W + + R+ +
Sbjct: 476 TNIAPVFTQRPVD-TTVTDGMTAILRCE-VSGAPKPAITWKRENHILASGSVRIPRFMLL 533
Query: 193 HNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGT 252
+G L + V +QD +Y+C A +L T V RT S ++P
Sbjct: 534 ESGGLQIAPVFIQD-AGNYTCYA---------ANTEGSLNASATLTVWNRT-SIVHP--- 579
Query: 253 ASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL---PSDKAKF-ENFNKALRITNVSE 308
+V++G L C A+ P + + K ++ PS ++ + +L I+
Sbjct: 580 PEDHVVIKGTTATLHCGATHDPRVSLRYVWKKDNVALTPSSTSRIVVEKDGSLLISQTWS 639
Query: 309 EDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDG------RLVCRANG 362
D G+Y C ++ G+ + V P+ P+NL+++P V +G
Sbjct: 640 GDIGDYSCEIVSEGGNDSRMARLEVIELPH---SPQNLLVSPNSSHSHAVVLSWVRPFDG 696
Query: 363 NPKPTVQWMV----NGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTS--NEHGY 416
N P + ++V N P + N E+ G T+ + ++ YQ NE G
Sbjct: 697 N-SPILYYIVELSENNSPWKVHLSNVGPEMTGVTV----SGLTPARTYQFRVCAVNEVGR 751
Query: 417 LLANAFVSVLDVP--PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLD 474
+A S L +P P P+N ++ RT P P + + +
Sbjct: 752 GQYSAETSRLMLPEEPPSAPPKN----IVASGRTNQSIMVQWQPPP------ETEHNGVL 801
Query: 475 GGNYHVYENGSL--EIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPT--RIYRMPED 530
G Y L E + + C+ T+++ + ++++ + ++
Sbjct: 802 RGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVT 861
Query: 531 QVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK----------EDDSLTIF 580
+ +G V+ + T+ +L + P N + + +++T+
Sbjct: 862 EYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVV 921
Query: 581 GVAERDQGSYTCVASTELDQDLAKAYLTVLADQATP------TNRLAALPKGRPDRPRDL 634
+A G + T L + A Y T + TP T +L + +P L
Sbjct: 922 TIAPDFHGVHH-GHITNLKKFTA--YFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHL 978
Query: 635 ELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSA-----V 689
T++ + S++++W N IT Y + +E + S+ ++NS +
Sbjct: 979 SFTEILDTSLKVSWQEPLEKNGIITGYQISWEV------YGRNDSRLTHTLNSTTHEYKI 1032
Query: 690 LRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWT 749
LS Y V A+ VG+ L + +SG PP+ G N + +
Sbjct: 1033 QGLSSLTTYTIDVAAVTAVGT---GLVTSSTISSGVPPDL-------PGAPSNLVISNIS 1082
Query: 750 PMNATSAFGPNL---RYIVKWRRRETREAWNNVTVWGSRYVVGQTP-----------VYV 795
P +AT F P I +W A + W + Y P Y
Sbjct: 1083 PRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYT 1142
Query: 796 PYEIRVQAENDFGKGP-EPESVIGYSGEDLPS-APRRFRVRQPNLETINLEW----DHPE 849
Y R++ N G P P S + + + P AP VR + ++ L W D
Sbjct: 1143 HYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQY 1202
Query: 850 HPNGIMIGYTLKY--VAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVG 907
+ N +GY +KY + V + + + + +FT++ + Y + A VG
Sbjct: 1203 NGNPESVGYRIKYWRSDLQSSAVAQVVSDRL---EREFTIEELEEWMEYELQMQAFNAVG 1259
Query: 908 SGEAVTEESPAPPNEATPTAAPPTLPPTTVGAT 940
+G +E E+ P+AAP + V +T
Sbjct: 1260 AG-PWSEVVRGRTRESVPSAAPENVSAEAVSST 1291
Score = 84.3 bits (207), Expect = 6e-16
Identities = 75/320 (23%), Positives = 144/320 (45%), Gaps = 21/320 (6%)
Query: 621 AALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEE----DQFQPGVWH 676
+ +P P P +L +++++ RS L + PG + I+ ++V+ + D+ + +
Sbjct: 1063 SGVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLY 1122
Query: 677 DHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKG 736
+ P + + L+PY +Y+FR+ +N VG S S S +T APP+ P V
Sbjct: 1123 EEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTV 1182
Query: 737 EGTRKNNMEITWTPMNATSAFG--PNLRYIVKWRRRETREAWNNVTV---WGSRYVVGQT 791
+ ++ + W P+ + G ++ Y +K+ R + + + V + + +
Sbjct: 1183 RTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEEL 1242
Query: 792 PVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPS-APRRFRVRQPNLETINLEWDH-PE 849
++ YE+++QA N G GP E V G + E +PS AP + I L W PE
Sbjct: 1243 EEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPE 1302
Query: 850 H-PNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGS 908
NG+++GY + + A + + + + Q+ V Y + A T++G+
Sbjct: 1303 QDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFV-LYELQVLAFTRIGN 1361
Query: 909 G--------EAVTEESPAPP 920
G E +++P PP
Sbjct: 1362 GVPSTPLILERTKDDAPGPP 1381
Score = 55.8 bits (133), Expect = 2e-07
Identities = 83/374 (22%), Positives = 140/374 (37%), Gaps = 32/374 (8%)
Query: 256 QMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYF 315
Q+ L G L+L C+A G + W + +L + ++++ I ++ + D+G Y
Sbjct: 114 QIHLEGNRLVLTCLAEGSWPLEFKWMRDDSELTTYSSEYKYI-----IPSLQKLDAGFYR 168
Query: 316 CLASNKMGS-IRHTISVRVKAAPYWLDEPKNLILAPGEDGRL-VCRANGNPKPTVQWMVN 373
C+ N+MG+ ++ V+V ++D + ++ G L + P+P V W
Sbjct: 169 CVVRNRMGALLQRKSEVQVAYMGSFMDTDQRKTVSQGRAAILNLLPITSYPRPQVTWFRE 228
Query: 374 GEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNE-HGYLLANAFVSVL------ 426
G + P N + ++ T S Y NE +G + F+ +
Sbjct: 229 GHKI--IPSNRIAITLENQLVILATTTSDAGAYYVQAVNEKNGENKTSPFIHLSIARDVG 286
Query: 427 ---DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYEN 483
+ P ++ P V + T L+C P+ L G + G +
Sbjct: 287 TPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRNGVRITSGLHSF--G 344
Query: 484 GSLEIKMIRKEDQGIYTCVATNILGKAENQVR----LEVKDPTRIYRMPEDQV-ARRGTT 538
L I D G Y C A + G A R L + +P PE ++ A T
Sbjct: 345 RRLTISNPTSADTGPYVCEAA-LPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEET 403
Query: 539 VQLECRVKHDPSLKLTVSWLKDDEPL-YIGNRMKK--EDDSLTIFGVAERDQGSYTCVAS 595
V + C+ P T+ W KD + + N K L I + D G + C AS
Sbjct: 404 VDIGCQAMGVP--LPTLQWYKDAISISRLQNPRYKVLASGGLRIQKLRPEDSGIFQCFAS 461
Query: 596 TELDQDLAKAYLTV 609
E + YL V
Sbjct: 462 NEGGEIQTHTYLDV 475
Score = 54.7 bits (130), Expect = 5e-07
Identities = 37/104 (35%), Positives = 50/104 (48%), Gaps = 7/104 (6%)
Query: 618 NRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHD 677
N A +G P PRD+ +T A + L W G + ++P T YV++ G+W
Sbjct: 1893 NITAGPAEGSPGSPRDVLVTKSASE-LTLQWTEGHSGDTPTTGYVIEARPSD--EGLWDM 1949
Query: 678 HSK-YPGSVNSAVLRLSPY---VNYQFRVIAINEVGSSHPSLPS 717
K P S S L L V Y+FRV+A+NE G PS PS
Sbjct: 1950 FVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPS 1993
Score = 40.8 bits (94), Expect = 0.008
Identities = 34/127 (26%), Positives = 52/127 (40%), Gaps = 11/127 (8%)
Query: 823 DLPSAPRRFRVRQPNLE---TINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFS 879
+LP +P+ V PN + L W P N ++ Y ++ N K + N
Sbjct: 666 ELPHSPQNLLV-SPNSSHSHAVVLSWVRPFDGNSPILYYIVELSENNSP--WKVHLSNVG 722
Query: 880 PNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAPPTLPPTTVGA 939
P T TV P Y+F + A +VG G+ E S E PP+ PP + A
Sbjct: 723 PEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPE-----EPPSAPPKNIVA 777
Query: 940 TGAVSST 946
+G + +
Sbjct: 778 SGRTNQS 784
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 196 bits (497), Expect = 2e-49
Identities = 206/831 (24%), Positives = 335/831 (40%), Gaps = 70/831 (8%)
Query: 57 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 116
+ +++ C A+G+ F W N+R + S+ R +D + G Y
Sbjct: 42 NRLVLTCMAEGSWPLEFKWLHNNRELT-----KFSLEYRYMITSLD-------RTHAGFY 89
Query: 117 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWM 176
+C RN+ G L + +QV+ + +E V G ++ P P + W
Sbjct: 90 RCIVRNRMGALLQRQTEVQVAYMGSF-EEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWF 148
Query: 177 SSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKN-------PF 229
+ I R++ L + + D A ++ + KN P
Sbjct: 149 RDGRK-IPPSSRIAITLENTLVILSTVAPD--------AGRYYVQAVNDKNGDNKTSQPI 199
Query: 230 TLKVLTTRGVAER-TPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPD--IAWYKKGGD 286
TL V G A+ P+ + P S +V ++ LEC+A+ P I W KK G
Sbjct: 200 TLTVENVGGPADPIAPTIIIPPKNTS--VVAGTSEVTLECVANARPLIKLHIIW-KKDGV 256
Query: 287 LPSDKAKFENFNKALRITNVSEEDSGEYFC---LASNKMGSIRHTISVRVKAAPYWLDEP 343
L S + N+ L I N + D+G Y C L S+ + S+ + V P ++ EP
Sbjct: 257 LLS--GGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEP 314
Query: 344 KNLILAPGEDG-RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISS 402
+ I A E + C+A G P P++ W + ++ R+ +
Sbjct: 315 ERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDD 374
Query: 403 RAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTR-LDCPFFGSPIPT 461
++QC N G + + +++V + P + R L ++ + L C G+P P
Sbjct: 375 TGMFQCFARNAAGEVQTSTYLAVTSIAPNIT--RGPLDSTVIDGMSVVLACETSGAPRPA 432
Query: 462 LRWFKNGQ---GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV 518
+ W K + ++ + E+GSL I D G YTC+ATN G E L V
Sbjct: 433 ITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVV 492
Query: 519 KDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK---KEDD 575
TRI + P+DQ +GT + C V HDP + + W KD L + + +
Sbjct: 493 WARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNG 552
Query: 576 SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLE 635
SL I D G+YTC + D A+L R+ LP P+ P
Sbjct: 553 SLHISQTWSGDIGTYTCRVISAGGNDSRSAHL-----------RVRQLPHA-PEHP-VAT 599
Query: 636 LTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPY 695
L+ + R++ LTW NSP+ Y+++ E+ P S P + + V L P
Sbjct: 600 LSTVERRAINLTWTKPFDGNSPLIRYILEMSENN-APWTVLLASVDPKATSVTVKGLVPA 658
Query: 696 VNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATS 755
+YQFR+ A+N+VG S +ER PP + P +V G ++ I W P +
Sbjct: 659 RSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESH 718
Query: 756 AFGPNLRYIVKW--RRRETREAWNNVT-VWGSRYVVGQTPVYVPYEIRVQAENDFGKGPE 812
G YI+++ + N+T + ++ ++ YEI V A N G G
Sbjct: 719 QNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVY 778
Query: 813 PESVIGYSGEDLPSA-PRRFRVRQPNLETINLEWD--HPEHPNGIMIGYTL 860
V ++ + +P+ P N TI W+ P+ NGI GY L
Sbjct: 779 SSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKL 829
Score = 127 bits (319), Expect = 7e-29
Identities = 154/699 (22%), Positives = 266/699 (38%), Gaps = 62/699 (8%)
Query: 266 LECIASGVPTPDIAWYKKGGDLPSDK-AKFENFNKA-LRITNVSEEDSGEYFCLASNKMG 323
+ C A GVP P I WYK + +K +F N L+I+ + +D+G + C A N G
Sbjct: 328 IPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAG 387
Query: 324 SIRHTISVRVKA-APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPP 382
++ + + V + AP P + + G L C +G P+P + W L S
Sbjct: 388 EVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSV 447
Query: 383 NPNR--EVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLI 440
R + +++ T IS Y C +N G A+A + V P++Q
Sbjct: 448 QLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQ-- 505
Query: 441 RVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNY---HVYENGSLEIKMIRKEDQG 497
VI + + C P T+R+ G+ L ++ + NGSL I D G
Sbjct: 506 SVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIG 565
Query: 498 IYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVK-------HDPS 550
YTC + G L V+ ++ PE VA T + + + P
Sbjct: 566 TYTCRVISAGGNDSRSAHLRVR---QLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPL 622
Query: 551 LKLTVSWLKDDEP-LYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
++ + +++ P + + + S+T+ G+ + A ++ +
Sbjct: 623 IRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKG-------- 674
Query: 610 LADQATPTNRLAALPKGRPDRP-RDLELTDLAERSVRLTWIPGDAN--NSPITDYVVQFE 666
Q + +LP+ P P +++ + +S+ + W P + N + Y++++
Sbjct: 675 ---QFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYC 731
Query: 667 EDQFQPGVWHDHSKYPGSVNSAVLR-LSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGA 725
G + + VN+ +L L + NY+ V A N G S + G
Sbjct: 732 LAGLPVG-YQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGV 790
Query: 726 PPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY-IVKWRRRETREAWNNVTVWGS 784
P PG+V E T + TW + G N Y ++ W + E VT+ +
Sbjct: 791 PTVP-PGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEE----VTMVTA 845
Query: 785 RY---------VVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQ 835
R V + Y V G GP + + ED+P +
Sbjct: 846 RPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSE 905
Query: 836 PNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQT-KFTVQRTDPVS 894
++ + W P NGI+ GY + + +N T V ++ PN T ++ V ++
Sbjct: 906 ILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTR---VTHYLPNVTLEYRVTGLTALT 962
Query: 895 RYRFTLSARTQVGSGE--AVTEESPAPPNEATPTAAPPT 931
Y ++A T G G+ A T S PP PPT
Sbjct: 963 TYTIEVAAMTSKGQGQVSASTISSGVPPE----LPGPPT 997
Score = 97.8 bits (242), Expect = 6e-20
Identities = 98/427 (22%), Positives = 170/427 (39%), Gaps = 36/427 (8%)
Query: 613 QATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQP 672
Q + + + +P P P +L ++++ RSV L + PG + I+ ++V+ +
Sbjct: 978 QVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGE 1037
Query: 673 GV-W---HDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPE 728
G W H S P + + V L+P+ Y FR+ +N VG+S PS PS + +T APP+
Sbjct: 1038 GEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPD 1097
Query: 729 SNPGDVKGEGTRKNNMEITWTPMNATSAFG--PNLRYIVKWRRRETREAWNNVTVWG--- 783
P +V + ++ + W P+ G ++ Y +K+ R + + V
Sbjct: 1098 MAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVE 1157
Query: 784 SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSA-PRRFRVRQPNLETIN 842
Y + + Y ++VQA N G GP ++V+G + E +PS+ P ++
Sbjct: 1158 RDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSML 1217
Query: 843 LEWDH-PE-HPNGIMIGYTLKYVAFNG-TKVGKQIVENFSPNQTKFTVQRTDPVSRYRFT 899
+ W PE NG+++GY + Y + T+ +VE S + T Y
Sbjct: 1218 VRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLT--GLGKYVLYEVQ 1275
Query: 900 LSARTQVGSGEAVTEESPAPPNEATPTAAPPTLPPTTVGATGAVSSTDATAIAATTEATT 959
+ A T++G G P+ PP V + T+
Sbjct: 1276 VLAFTRIGDGS-------------------PSHPPILERTLDDVPGPPMGILFPEVRTTS 1316
Query: 960 VPII--PTVAPTTIATTTTVATTTTTTAAATTTTESPPTTTSGTKIHESAPDEQSIWNVT 1017
V +I P AP I + TT A T T E + P+ ++ +T
Sbjct: 1317 VRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRIT 1376
Query: 1018 VLPNSKW 1024
W
Sbjct: 1377 AQTRKGW 1383
Score = 93.6 bits (231), Expect = 1e-18
Identities = 130/569 (22%), Positives = 216/569 (37%), Gaps = 68/569 (11%)
Query: 628 PDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNS 687
P RP ++ D+ RSV L+W PG SP+ Y +Q E G W HS S
Sbjct: 1403 PSRPM-VQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRE--LPSGRWALHSASVSHNAS 1459
Query: 688 AVL--RLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNME 745
+ + RL P+ +Y+FRV A N++G S S SE T A P+ P + ++
Sbjct: 1460 SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVL 1519
Query: 746 ITWTPMNATSAFGPNLRYIVKWR-------RRETREAWNNV-TVWG-------------- 783
I W P G L + +++R R T NN W
Sbjct: 1520 IRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRP 1579
Query: 784 --SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLP-SAPRRFRVRQPNLET 840
++Y + + YEIR+ N G+GP + GE +P +APR V
Sbjct: 1580 SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQ 1639
Query: 841 INLEWDHP--EHPNGIMIGYTLKYVAFNGTKVGKQIVENF-SPNQTKFTVQRTDPVSRYR 897
+++ W+ P + NG + GY + + + +++ F + N K ++ + Y
Sbjct: 1640 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVK--LKNLTGYTAYM 1697
Query: 898 FTLSARTQVGSGEAVTEESPAPPNEATPTAAPPTLPPTTVGATGAVSSTDA----TAIAA 953
+++A G G T + +A P +AP ++ + + T S +A I
Sbjct: 1698 VSVAAFNAAGDGPRST-PTQGQTQQAAP-SAPSSVKFSELTTTSVNVSWEAPQFPNGILE 1755
Query: 954 TTEATTVPIIPTVAPTTIATT--------------TTVATTTTTTAAATTTTESPPTTTS 999
P P + I T T A T T P +
Sbjct: 1756 GYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEAN 1815
Query: 1000 -GTKIHESAPDEQSIWNVTVLPNSKWANITWKH---NFGPGTDFVVEYIDSNH-----TK 1050
T E AP + ++ S I W GP T +V+E S+
Sbjct: 1816 VTTGPGEGAPGPPGV--PIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILI 1873
Query: 1051 KTVPVKAQAQPIQLTDLYPGMTYTLRVYSRDNEGISSTVITFMTSTAYTNNQADIATQGW 1110
K +P + + + L PG++Y RV + ++ G + + A N + W
Sbjct: 1874 KDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKAN--PFYEEWW 1931
Query: 1111 FIGLMCAIALLVLILLIVCFIKRSRGGKY 1139
F+ ++ + L+ ++LL+ I R + KY
Sbjct: 1932 FLVVIALVGLIFILLLVFVLIIRGQSKKY 1960
Score = 83.6 bits (205), Expect = 1e-15
Identities = 77/326 (23%), Positives = 136/326 (41%), Gaps = 12/326 (3%)
Query: 616 PTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIP---GDANNSPIT-DYVVQFEEDQFQ 671
P+ ++ L P ++ L +E S+ L W+P + N +P + Y +++
Sbjct: 1085 PSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGH 1144
Query: 672 PGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNP 731
+ + + L + Y+ +V A N +GS P + RT + P S P
Sbjct: 1145 GKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGP 1203
Query: 732 GDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQT 791
+V T ++M + W+ + G L Y V ++ +++ V G+ Q
Sbjct: 1204 TNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQL 1263
Query: 792 P---VYVPYEIRVQAENDFGKG-PEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEWDH 847
YV YE++V A G G P ++ + +D+P P + ++ L W
Sbjct: 1264 TGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQP 1323
Query: 848 PEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVG 907
P PNGI++ Y + + N T VE +P+ ++T P S Y F ++A+T+ G
Sbjct: 1324 PAAPNGIILAYQITH-RLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKG 1382
Query: 908 SGEAVTEESPAPPNEATPTAAPPTLP 933
GEA E+ E PP+ P
Sbjct: 1383 WGEAA--EALVVTTEKRDRPQPPSRP 1406
Score = 72.0 bits (175), Expect = 3e-12
Identities = 77/318 (24%), Positives = 123/318 (38%), Gaps = 40/318 (12%)
Query: 39 QPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGT 98
+PP K+ + + + I C+AKG P PS W +++ + K R R G
Sbjct: 306 EPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGL 365
Query: 99 LVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPL 158
+ SG P++ G +QCFARN G ++ S +P + LD V+ +G +
Sbjct: 366 QI----SGLVPDD-TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVI-DGMSV 419
Query: 159 TLQCNPPPGLPSPVIFWMSSS---MEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNA 215
L C G P P I W Q R + +G L S + D T Y+C A
Sbjct: 420 VLACE-TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGT-YTCLA 477
Query: 216 RFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGT-----ASSQMVLRGMDLLLECIA 270
+RGV E + + T Q V++G + C
Sbjct: 478 ------------------TNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGV 519
Query: 271 SGVPTPDI--AWYKKGGDLPSD---KAKFENFNKALRITNVSEEDSGEYFCLASNKMGSI 325
+ P I W K G L ++ + + + N +L I+ D G Y C + G+
Sbjct: 520 THDPRVTIRYIWEKDGATLGTESHPRIRLDR-NGSLHISQTWSGDIGTYTCRVISAGGND 578
Query: 326 RHTISVRVKAAPYWLDEP 343
+ +RV+ P+ + P
Sbjct: 579 SRSAHLRVRQLPHAPEHP 596
Score = 44.3 bits (103), Expect = 7e-04
Identities = 38/126 (30%), Positives = 52/126 (41%), Gaps = 11/126 (8%)
Query: 824 LPSAPRRFRVRQPNLE--TINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPN 881
LP AP +E INL W P N +I Y L+ N ++ + P
Sbjct: 589 LPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWT--VLLASVDPK 646
Query: 882 QTKFTVQRTDPVSRYRFTLSARTQVGSGE-AVTEESPAPPNEATPTAAPPTLPPTTVGAT 940
T TV+ P Y+F L A VG G+ + E + P E PPT PP V A+
Sbjct: 647 ATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEE------PPTAPPQNVIAS 700
Query: 941 GAVSST 946
G + +
Sbjct: 701 GRTNQS 706
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 194 bits (494), Expect = 3e-49
Identities = 156/518 (30%), Positives = 232/518 (44%), Gaps = 35/518 (6%)
Query: 19 LSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRN 78
L L G + + +D S + PP I + + D IV + + C+A+G P P+ W ++
Sbjct: 9 LLLCGFLYVRVDGSRLRQEDFPPRIVEHPS-DVIVSKGEPTTLNCKAEGRPTPTIEWYKD 67
Query: 79 SRFFNIAKDPRVSMRRR--SGTLV-IDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQ 135
KD S R SG+L + G R + EG Y C ARN G A+S L+
Sbjct: 68 GERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLE 127
Query: 136 VSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNG 195
V+ ++N VVV G P L+C PP G P P I+W + +++R+S G
Sbjct: 128 VALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISI-RGG 186
Query: 196 DLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASS 255
L SN D Y+C T+ + +++ ++ V ER P+F+ +
Sbjct: 187 KLMISNTRKSDAGM-YTCVG----TNMVGERDSDPAELT----VFER-PTFLR---RPIN 233
Query: 256 QMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYF 315
Q+VL + C G P P + W K DLP + ++ + LRI D G Y
Sbjct: 234 QVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKD-DYTLRIKKTMSTDEGTYM 292
Query: 316 CLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGE 375
C+A N++G + + ++ V+A P ++ P++ I+A G C GNP+P V W G
Sbjct: 293 CIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGS 352
Query: 376 -----PLQSAPPNPNREVA--GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDV 428
P Q PN V+ GD I + Q S Y C G +LA A + V DV
Sbjct: 353 QNLLFPNQPQQPNSRCSVSPTGDLTI-TNIQRSDAGYYICQALTVAGSILAKAQLEVTDV 411
Query: 429 -----PPRML-SPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYE 482
PP +L P NQ + V L C G P+P + W K G + E
Sbjct: 412 LTDRPPPIILQGPANQTLAV--DGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQE 469
Query: 483 NGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD 520
G+L+IK +R D G YTCVAT+ G+ L+V +
Sbjct: 470 QGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTE 507
Score = 192 bits (489), Expect = 1e-48
Identities = 215/835 (25%), Positives = 341/835 (40%), Gaps = 92/835 (11%)
Query: 133 RLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQG 192
RL+ P E+ V+V +G P TL C G P+P I W E + DK +
Sbjct: 23 RLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAE-GRPTPTIEWYKDG-ERVETDKDDPRS 80
Query: 193 H-----NGDLYFSNVM----LQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERT 243
H +G L+F ++ + + Y C AR + + + +L+V R +
Sbjct: 81 HRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNA--SLEVALLRDDFRQN 138
Query: 244 PSFMYPQGTASSQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGDLPSDKAKFENFNKALR 302
P+ + +V G +LEC G P P I W K + + + L
Sbjct: 139 PTDV---------VVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLM 189
Query: 303 ITNVSEEDSGEYFCLASNKMGSI-RHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRAN 361
I+N + D+G Y C+ +N +G + V P +L P N ++ E C+
Sbjct: 190 ISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQ 249
Query: 362 GNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDTQISSRAVYQCNTSNEHGYLLAN 420
G+P+PTV+W + L P ++ D T+ + T + Y C N G + A+
Sbjct: 250 GDPQPTVRWKKDDADL----PRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEAS 305
Query: 421 AFVSVLDVPPRMLSPRNQLIRVILYNRT-RLDCPFFGSPIPTLRWFKNGQGSNL------ 473
A ++V P ++ PR+Q ++ RT C G+P P + W K G + L
Sbjct: 306 ATLTVRAPPQFVVRPRDQ---IVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQ 362
Query: 474 -DGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD------PTRIYR 526
V G L I I++ D G Y C A + G + +LEV D P I +
Sbjct: 363 QPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQ 422
Query: 527 MPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDE--PLYIGNRMKKEDDSLTIFGVAE 584
P +Q T L+C+ DP +SWLK+ P +E +L I +
Sbjct: 423 GPANQTLAVDGTALLKCKATGDPLP--VISWLKEGFTFPGRDPRATIQEQGTLQIKNLRI 480
Query: 585 RDQGSYTCVASTELDQDLAKAYLTVLADQATPTNR--LAALPKGRPDRPRDLELTDLAER 642
D G+YTCVA++ + A L V AT + L+ LP G P +P ++TD+ +
Sbjct: 481 SDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLP-GPPSKP---QVTDVTKN 536
Query: 643 SVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRV 702
SV L+W PG P + Y+++ Q W + + + V L P Y F V
Sbjct: 537 SVTLSWQPGTPGTLPASAYIIE-AFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMV 595
Query: 703 IAINEVGSSHPSLPSERYRTSGAPP----------ESNPGDVKGEGTRKNN--------M 744
AIN G S PS S+ RT P + GDV R +N +
Sbjct: 596 RAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVL---VRLHNPVVLTPTTV 652
Query: 745 EITWTPMNATSAFGPNLRYIVKWRR-RETREAWNNVTV---WGSRYVVGQTPVYVPYEIR 800
++TWT ++ F R + + + +W N+ V+ V YEI+
Sbjct: 653 QVTWT-VDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIK 711
Query: 801 VQAENDFGKGPEPESVIGYSGEDLPSAPRR----FRVRQPNLETINLEWD--HPEHPNGI 854
V+ + +G + ES + E+ PSAP + V N +I++ WD P+H NGI
Sbjct: 712 VRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGI 771
Query: 855 MIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSG 909
+ Y + + G + I + + P +YR ++A T G G
Sbjct: 772 IQEYKIWCL---GNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVG 823
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 192 bits (489), Expect = 1e-48
Identities = 215/835 (25%), Positives = 341/835 (40%), Gaps = 92/835 (11%)
Query: 133 RLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQG 192
RL+ P E+ V+V +G P TL C G P+P I W E + DK +
Sbjct: 39 RLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAE-GRPTPTIEWYKDG-ERVETDKDDPRS 96
Query: 193 H-----NGDLYFSNVM----LQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERT 243
H +G L+F ++ + + Y C AR + + + +L+V R +
Sbjct: 97 HRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNA--SLEVALLRDDFRQN 154
Query: 244 PSFMYPQGTASSQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGDLPSDKAKFENFNKALR 302
P+ + +V G +LEC G P P I W K + + + L
Sbjct: 155 PTDV---------VVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLM 205
Query: 303 ITNVSEEDSGEYFCLASNKMGSI-RHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRAN 361
I+N + D+G Y C+ +N +G + V P +L P N ++ E C+
Sbjct: 206 ISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQ 265
Query: 362 GNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDTQISSRAVYQCNTSNEHGYLLAN 420
G+P+PTV+W + L P ++ D T+ + T + Y C N G + A+
Sbjct: 266 GDPQPTVRWKKDDADL----PRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEAS 321
Query: 421 AFVSVLDVPPRMLSPRNQLIRVILYNRT-RLDCPFFGSPIPTLRWFKNGQGSNL------ 473
A ++V P ++ PR+Q ++ RT C G+P P + W K G + L
Sbjct: 322 ATLTVRAPPQFVVRPRDQ---IVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQ 378
Query: 474 -DGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD------PTRIYR 526
V G L I I++ D G Y C A + G + +LEV D P I +
Sbjct: 379 QPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQ 438
Query: 527 MPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDE--PLYIGNRMKKEDDSLTIFGVAE 584
P +Q T L+C+ DP +SWLK+ P +E +L I +
Sbjct: 439 GPANQTLAVDGTALLKCKATGDPLP--VISWLKEGFTFPGRDPRATIQEQGTLQIKNLRI 496
Query: 585 RDQGSYTCVASTELDQDLAKAYLTVLADQATPTNR--LAALPKGRPDRPRDLELTDLAER 642
D G+YTCVA++ + A L V AT + L+ LP G P +P ++TD+ +
Sbjct: 497 SDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLP-GPPSKP---QVTDVTKN 552
Query: 643 SVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRV 702
SV L+W PG P + Y+++ Q W + + + V L P Y F V
Sbjct: 553 SVTLSWQPGTPGTLPASAYIIE-AFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMV 611
Query: 703 IAINEVGSSHPSLPSERYRTSGAPP----------ESNPGDVKGEGTRKNN--------M 744
AIN G S PS S+ RT P + GDV R +N +
Sbjct: 612 RAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVL---VRLHNPVVLTPTTV 668
Query: 745 EITWTPMNATSAFGPNLRYIVKWRR-RETREAWNNVTV---WGSRYVVGQTPVYVPYEIR 800
++TWT ++ F R + + + +W N+ V+ V YEI+
Sbjct: 669 QVTWT-VDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIK 727
Query: 801 VQAENDFGKGPEPESVIGYSGEDLPSAPRR----FRVRQPNLETINLEWD--HPEHPNGI 854
V+ + +G + ES + E+ PSAP + V N +I++ WD P+H NGI
Sbjct: 728 VRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGI 787
Query: 855 MIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSG 909
+ Y + + G + I + + P +YR ++A T G G
Sbjct: 788 IQEYKIWCL---GNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVG 839
Score = 192 bits (487), Expect = 2e-48
Identities = 151/497 (30%), Positives = 223/497 (44%), Gaps = 35/497 (7%)
Query: 40 PPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRR--SG 97
PP I + + D IV + + C+A+G P P+ W ++ KD S R SG
Sbjct: 46 PPRIVEHPS-DVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSG 104
Query: 98 TLV-IDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGA 156
+L + G R + EG Y C ARN G A+S L+V+ ++N VVV G
Sbjct: 105 SLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGE 164
Query: 157 PLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNAR 216
P L+C PP G P P I+W + +++R+S G L SN D Y+C
Sbjct: 165 PAILECQPPRGHPEPTIYWKKDKVRIDDKEERISI-RGGKLMISNTRKSDAGM-YTCVG- 221
Query: 217 FHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTP 276
T+ + +++ ++ V ER P+F+ +Q+VL + C G P P
Sbjct: 222 ---TNMVGERDSDPAELT----VFER-PTFLR---RPINQVVLEEEAVEFRCQVQGDPQP 270
Query: 277 DIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAA 336
+ W K DLP + ++ + LRI D G Y C+A N++G + + ++ V+A
Sbjct: 271 TVRWKKDDADLPRGRYDIKD-DYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAP 329
Query: 337 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGE-----PLQSAPPNPNREVA-- 389
P ++ P++ I+A G C GNP+P V W G P Q PN V+
Sbjct: 330 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 389
Query: 390 GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDV-----PPRML-SPRNQLIRVI 443
GD I + Q S Y C G +LA A + V DV PP +L P NQ + V
Sbjct: 390 GDLTI-TNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAV- 447
Query: 444 LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 503
L C G P+P + W K G + E G+L+IK +R D G YTCVA
Sbjct: 448 -DGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVA 506
Query: 504 TNILGKAENQVRLEVKD 520
T+ G+ L+V +
Sbjct: 507 TSSSGETSWSAVLDVTE 523
Score = 40.0 bits (92), Expect = 0.014
Identities = 33/139 (23%), Positives = 61/139 (43%), Gaps = 9/139 (6%)
Query: 12 AAFLLC-LLSLGGAIEIPMDPSIQNELT-QPPTITKQSAKDHIVDPRDNILIECEAKGNP 69
A + +C L++ G+I + + LT +PP I Q + + L++C+A G+P
Sbjct: 402 AGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDP 461
Query: 70 APSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALS 129
P W + F +DPR +++ + + + R G Y C A + G
Sbjct: 462 LPVISWLKEGFTFP-GRDPRATIQEQGTLQIKNLRISD-----TGTYTCVATSSSGETSW 515
Query: 130 NRIRLQVSKSPLWPKENLD 148
+ + L V++S +N D
Sbjct: 516 SAV-LDVTESGATISKNYD 533
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 184 bits (468), Expect = 3e-46
Identities = 236/950 (24%), Positives = 379/950 (39%), Gaps = 121/950 (12%)
Query: 42 TITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVI 101
TI+ + K + + + C G W RN N K+ R++ L++
Sbjct: 317 TISPRKVKSSV---GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHE-NLIM 372
Query: 102 D--FRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPK--ENLDPVVVQEGAP 157
D +S G G YQCF R LS + +QV PK VV P
Sbjct: 373 DHMVKSDG------GAYQCFVRK---DKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEP 423
Query: 158 LTLQCNPPPGLPSPVIFWMSSSMEPITQ--DKRVSQ---GHNGDLYFSNVMLQDMQTD-- 210
++L CN G P P I W +PI + R+SQ + + N+ ++
Sbjct: 424 VSLMCN-VKGTPLPTITWTLDD-DPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGV 481
Query: 211 YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIA 270
Y C A N VL + R P+ + P ++ + G D + C
Sbjct: 482 YRCTA-----------NNSAGVVLYQARINVRGPASIRPMKNITA---IAGRDTYIHCRV 527
Query: 271 SGVPTPDIAWYKKGGDLPSD--KAKFENFNKALRITNVSEE-DSGEYFC-LASNKMGSIR 326
G P I WYK LP + + FEN N L++++V +E D GEY C + S
Sbjct: 528 IGYPYYSIKWYKNSNLLPFNHRQVAFEN-NGTLKLSDVQKEVDEGEYTCNVLVQPQLSTS 586
Query: 327 HTISVRVKAAPYW--LDEPKNLILAPGEDGRLVC-RANGNPKPTVQWMVNGEPLQSAPPN 383
++ V VK P+ + P+ I G+ + C +G+ T+ W +G P+
Sbjct: 587 QSVHVTVKVPPFIQPFEFPRFSI---GQRVFIPCVVVSGDLPITITWQKDGRPIPG---- 639
Query: 384 PNREVAGDTIIFRDT-QISSRAV-----YQCNTSNEHGYLLANAFVSVLDVPPRMLSPRN 437
+ V D I F + +IS+ ++ Y C NE + + + V P ++ PR+
Sbjct: 640 -SLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRD 698
Query: 438 QLIRVILYNRTRLDCPFFGSPIPTLRW-FKNGQG-----SNLDGGNYHVYENGSLEIKMI 491
Q I L+C G P+PT+ W F G G G V NGSL IK +
Sbjct: 699 Q--DGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHV 756
Query: 492 RKEDQGIYTCVATNILG-KAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPS 550
+ED G Y C +N +G + L VK P I P +A +G ++ C +
Sbjct: 757 VEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEK- 815
Query: 551 LKLTVSWLKDDEPL------YIGNRMKKEDD---SLTIFGVAERDQGSYTCVASTELDQD 601
+ V W K+D + Y+ + + ++ +L I D G ++C A +D
Sbjct: 816 -PIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGED 874
Query: 602 LAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDY 661
LTV P P ++E+ D+ R++ L W G NSPIT Y
Sbjct: 875 RGIIQLTV----------------QEPPDPPEIEIKDVKARTITLRWTMGFDGNSPITGY 918
Query: 662 VVQFEEDQFQPGVWHDHSKYPGSVNSA-VLRLSPYVNYQFRVIAINEVGSSHPSLPSERY 720
++ + +NSA ++ + P Y R+ A N +G S PS +E
Sbjct: 919 DIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPS--NELT 976
Query: 721 RTSG-APPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRET--REAWN 777
T+ A P+ P +V E ++ +TW G Y + +R T +N
Sbjct: 977 ITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFN 1036
Query: 778 NVTVWGSR----YVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPS-APRRFR 832
++V S Y + + Y + VQA N G GP + +I + ED+PS P +
Sbjct: 1037 IISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQ 1096
Query: 833 VRQPNLETINLEWD--HPEHPNGIMIGYTLKYVA-FNGTKVGKQIVENFSPNQTKFTVQR 889
+ E+I++ W E NGI+ G+ + Y A ++G+ ++N + Q +
Sbjct: 1097 AIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGELGE--IKNITTTQPSLELDG 1154
Query: 890 TDPVSRYRFTLSARTQVGSG-------EAVTEESPAPPNEATPTAAPPTL 932
+ + Y + A T+ G G E+ P PP AA ++
Sbjct: 1155 LEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASM 1204
Score = 154 bits (388), Expect = 7e-37
Identities = 196/905 (21%), Positives = 342/905 (37%), Gaps = 90/905 (9%)
Query: 50 DHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRP 109
+ +V P + + + C KG P P+ WT + R+S S V+ + +
Sbjct: 415 EKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSS 474
Query: 110 EEYEGE-YQCFARNKFGTALSN-RIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPG 167
+ +G Y+C A N G L RI ++ S + P +N+ + G + C G
Sbjct: 475 QVRDGGVYRCTANNSAGVVLYQARINVRGPAS-IRPMKNITAIA---GRDTYIHCRVI-G 529
Query: 168 LPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKN 227
P I W +S ++V+ +NG L S+V + + +Y+CN + Q
Sbjct: 530 YPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSV 589
Query: 228 PFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTP-DIAWYKKGGD 286
T+KV P F+ P + G + + C+ P I W K G
Sbjct: 590 HVTVKV----------PPFIQPFEFPRFSI---GQRVFIPCVVVSGDLPITITWQKDGRP 636
Query: 287 LPSDKA-KFEN--FNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 343
+P +N F +LRI+N+S +G Y C+A N+ ++ H + V+ P ++ +P
Sbjct: 637 IPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP 696
Query: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVN---GEPLQSAPPNPNREV---AGDTIIFRD 397
++ G+ L C A G P PT+ W + G P Q P N + + +++ +
Sbjct: 697 RDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVP-QFQPIALNGRIQVLSNGSLLIKH 755
Query: 398 TQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGS 457
Y C SN+ G ++ + + +P + S N + + + C G
Sbjct: 756 VVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTL-ATQGQKKEMSCTAHGE 814
Query: 458 PIPTLRWFKNGQGSNLDGGNYHVYEN-------GSLEIKMIRKEDQGIYTCVATNILGKA 510
+RW K + N + Y V +L+I +ED G ++C A N G+
Sbjct: 815 KPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGED 874
Query: 511 ENQVRLEVKDPTRIYRMPEDQVARRGTTVQ---------------LECRVKHDPSLKLTV 555
++L V++P + V R T++ +EC+ K D
Sbjct: 875 RGIIQLTVQEPPDPPEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSD------- 927
Query: 556 SWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQAT 615
SW + ++ +S TI + S A + + LT+ AD+A
Sbjct: 928 SWDSAQRTKDVSPQL----NSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAA 983
Query: 616 PTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDAN--NSPITDYVVQFEEDQFQPG 673
P P+++ L ++ +S+R+TW + N I Y + + E
Sbjct: 984 PDG-----------PPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGN 1032
Query: 674 VWHDHSKYPGSVNSAVL---RLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESN 730
+ S +S V L+ + Y V A N G+ PS T P
Sbjct: 1033 FQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTG-PSSQEIITTTLEDVPSYP 1091
Query: 731 PGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY-IVKWRRRETREAW--NNVTVWGSRYV 787
P +V+ T ++ I+W+ ++ + G + ++ W E N+T
Sbjct: 1092 PENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGELGEIKNITTTQPSLE 1151
Query: 788 VGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEWDH 847
+ Y Y I+V A G G E + + ED+P P + + + + W
Sbjct: 1152 LDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSWLP 1211
Query: 848 PEHPNGIMIGYTLKYVAFNGTKVGKQIVE-NFSPNQTKFTVQRTDPVSRYRFTLSARTQV 906
P NGI+ KY F I E SP+ + + +Y + A T
Sbjct: 1212 PLKLNGII----RKYTVFCSHPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSA 1267
Query: 907 GSGEA 911
G G +
Sbjct: 1268 GRGNS 1272
Score = 124 bits (310), Expect = 7e-28
Identities = 195/870 (22%), Positives = 333/870 (38%), Gaps = 121/870 (13%)
Query: 116 YQCFARNKFG--TALSNRIRLQVS---KSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPS 170
Y+C R+++ T SN RL VS S + D G + L C G P
Sbjct: 195 YRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKAL-GHPE 253
Query: 171 PVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFT 230
P W+ +M P+ R + G L N+ D + Y C + T
Sbjct: 254 PDYRWLKDNM-PLELSGRFQKTVTG-LLIENIRPSDSGS-YVCEVSNRYG---------T 301
Query: 231 LKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL-PS 289
KV+ V + + + P+ SS G + L C +G +++WY+ G L P
Sbjct: 302 AKVIGRLYVKQPLKATISPRKVKSSV----GSQVSLSCSVTGTEDQELSWYRNGEILNPG 357
Query: 290 DKAKFENFN-KALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVK-AAPYWLDEPKNLI 347
+ N + L + ++ + D G Y C S + + V ++ P + +
Sbjct: 358 KNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKV 417
Query: 348 LAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVA---GDTIIFRD---TQIS 401
++P E L+C G P PT+ W ++ +P+ + ++ G+ + + + +Q+
Sbjct: 418 VSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVR 477
Query: 402 SRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPT 461
VY+C +N G +L A ++V P + P I I T + C G P +
Sbjct: 478 DGGVYRCTANNSAGVVLYQARINVRG--PASIRPMKN-ITAIAGRDTYIHCRVIGYPYYS 534
Query: 462 LRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKE-DQGIYTCVATNILGKAE----NQVRL 516
++W+KN + NG+L++ ++KE D+G YTC N+L + + V +
Sbjct: 535 IKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTC---NVLVQPQLSTSQSVHV 591
Query: 517 EVKDPTRI--YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPL--YIGNRMKK 572
VK P I + P + +R V + C V L +T++W KD P+ +G +
Sbjct: 592 TVKVPPFIQPFEFPRFSIGQR---VFIPCVVVSG-DLPITITWQKDGRPIPGSLGVTIDN 647
Query: 573 ED--DSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDR 630
D SL I ++ G+YTC+A E ++ L V +P +
Sbjct: 648 IDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIV------------RVPPKFVVQ 695
Query: 631 PRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEED----QFQPGVWHDHSKYPGSVN 686
PRD + + ++V L A P+ V +F + QFQP + + + +
Sbjct: 696 PRDQD--GIYGKAVILNC---SAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGS 750
Query: 687 SAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPP--ESNPGDVKGEGTRKNNM 744
+ + + + N+VG+ + Y T P S P +K M
Sbjct: 751 LLIKHVVEEDSGYYLCKVSNDVGAD---VSKSMYLTVKIPAMITSYPNTTLATQGQKKEM 807
Query: 745 EITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQ-- 802
T A G IV+W + + + +RY+V V +Q
Sbjct: 808 SCT--------AHGEK-PIIVRWEKED-----RIINPEMARYLVSTKEVGEEVISTLQIL 853
Query: 803 -------------AENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEWDHPE 849
A N +G E +I + ++ P P ++ TI L W
Sbjct: 854 PTVREDSGFFSCHAINSYG---EDRGIIQLTVQEPPDPPE-IEIKDVKARTITLRWTMGF 909
Query: 850 HPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSG 909
N + GY ++ + + Q ++ SP T+ P S Y + A+ ++G
Sbjct: 910 DGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKS 969
Query: 910 EAVTEESPAPPNEATPTA--APPTLPPTTV 937
E P NE T TA A P PP V
Sbjct: 970 E--------PSNELTITADEAAPDGPPQEV 991
Score = 118 bits (295), Expect = 4e-26
Identities = 136/556 (24%), Positives = 216/556 (38%), Gaps = 46/556 (8%)
Query: 60 LIECEAKGNPAPSFHW--TRNSRFFNIAKDPRVSMRRRSGTL-VIDFR-SGGRPEEYEGE 115
L+ C A G P + W +++ P + +GTL + F S ++
Sbjct: 43 LVPCPAAGIPPVTLRWYLATGEEIYDV---PGIRHVHPNGTLQIFPFPPSSFSTLIHDNT 99
Query: 116 YQCFARNKFGTALSNRIRLQ-VSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPS--PV 172
Y C A N G S + ++ V + P + ++ G +C P + + V
Sbjct: 100 YYCTAENPSGKIRSQDVHIKAVLREPYTVR--VEDQKTMRGNVAVFKCIIPSSVEAYITV 157
Query: 173 IFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLK 232
+ W ++ + R G LY +V +D +Y C R +T +Q N L
Sbjct: 158 VSWEKDTVS-LVSGSRFLITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLF 216
Query: 233 VLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKA 292
V A PS + + + G + L C A G P PD W K L
Sbjct: 217 VSDP---ANSAPSIL---DGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELS-G 269
Query: 293 KFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGE 352
+F+ L I N+ DSG Y C SN+ G+ + + VK P+ + + G
Sbjct: 270 RFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGS 329
Query: 353 DGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG---DTIIFRDTQISSRAVYQCN 409
L C G + W NGE L P N + G + +I S YQC
Sbjct: 330 QVSLSCSVTGTEDQELSWYRNGEILN---PGKNVRITGINHENLIMDHMVKSDGGAYQCF 386
Query: 410 TSNEHGYLLANAFVSVL--DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKN 467
+ L A +V V+ D P+++S ++ + V L C G+P+PT+ W +
Sbjct: 387 VRKDK--LSAQDYVQVVLEDGTPKIISAFSEKV-VSPAEPVSLMCNVKGTPLPTITWTLD 443
Query: 468 GQGSNLDGGNYHVYEN--------GSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVK 519
L GG++ + + L I + D G+Y C A N G Q R+ V+
Sbjct: 444 -DDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVR 502
Query: 520 DPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK--KEDDSL 577
P I R ++ A G + CRV P ++ W K+ L +R + + +L
Sbjct: 503 GPASI-RPMKNITAIAGRDTYIHCRVIGYP--YYSIKWYKNSNLLPFNHRQVAFENNGTL 559
Query: 578 TIFGV-AERDQGSYTC 592
+ V E D+G YTC
Sbjct: 560 KLSDVQKEVDEGEYTC 575
Score = 60.1 bits (144), Expect = 1e-08
Identities = 75/303 (24%), Positives = 119/303 (39%), Gaps = 34/303 (11%)
Query: 317 LASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLV-CRANGNPKPTVQW-MVNG 374
LA + S + S + ++ Y+++ ++ G LV C A G P T++W + G
Sbjct: 4 LALSLFQSFANVFSEDLHSSLYFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATG 63
Query: 375 EPLQSAPPNPNREVAGDTIIFRDTQISSRAV-----YQCNTSNEHGYLLANAFVSVLDVP 429
E + P + G IF S + Y C N G + + DV
Sbjct: 64 EEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQ------DVH 117
Query: 430 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPT--------LRWFKNGQGSNLDGGNYHVY 481
+ + +RV R + F IP+ + W K+ S + G + +
Sbjct: 118 IKAVLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTV-SLVSGSRFLIT 176
Query: 482 ENGSLEIKMIRKEDQGIYT--CVATNILG---KAENQVRLEVKDPTR----IYRMPEDQV 532
G+L IK ++ ED G+Y C+ + + N RL V DP I + +
Sbjct: 177 STGALYIKDVQNED-GLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRK 235
Query: 533 ARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTC 592
A G V+L C+ P + WLKD+ PL + R +K L I + D GSY C
Sbjct: 236 AMAGQRVELPCKALGHP--EPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYVC 293
Query: 593 VAS 595
S
Sbjct: 294 EVS 296
Score = 58.2 bits (139), Expect = 5e-08
Identities = 58/215 (26%), Positives = 82/215 (38%), Gaps = 26/215 (12%)
Query: 519 KDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDE--PLYI---GNRMKKE 573
K P RI + L C+ DPS V W+KD P + G R
Sbjct: 1283 KAPARILTFSGTVTTPWMKDIVLPCKAVGDPSP--AVKWMKDSNGTPSLVTIDGRRSIFS 1340
Query: 574 DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRD 633
+ S I V D G Y+C+A+ D L V PD+PR
Sbjct: 1341 NGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVP---------------PDQPR- 1384
Query: 634 LELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLS 693
L ++ S+ L+W+PGD S I Y++Q+ ED + W P + + L
Sbjct: 1385 LTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQ--WGSFPISPSERSYRLENLK 1442
Query: 694 PYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPE 728
Y+F + A N VG S E +T G P+
Sbjct: 1443 CGTWYKFTLTAQNGVGPGRISEIIEA-KTLGKEPQ 1476
Score = 55.1 bits (131), Expect = 4e-07
Identities = 35/116 (30%), Positives = 53/116 (45%), Gaps = 21/116 (18%)
Query: 450 LDCPFFGSPIPTLRWFKNGQGS----NLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN 505
L C G P P ++W K+ G+ +DG ++ NGS I+ ++ ED G Y+C+A N
Sbjct: 1305 LPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRR-SIFSNGSFIIRTVKAEDSGYYSCIANN 1363
Query: 506 ILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDD 561
G E + L+V ++P DQ V S +T+SWL D
Sbjct: 1364 NWGSDEIILNLQV-------QVPPDQP---------RLTVSKTTSSSITLSWLPGD 1403
Score = 50.8 bits (120), Expect = 8e-06
Identities = 33/117 (28%), Positives = 57/117 (48%), Gaps = 10/117 (8%)
Query: 232 KVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS-- 289
+++T +A+ + GT ++ + D++L C A G P+P + W K PS
Sbjct: 1274 EIITVEPLAKAPARILTFSGTVTTPWM---KDIVLPCKAVGDPSPAVKWMKDSNGTPSLV 1330
Query: 290 --DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPK 344
D + N + I V EDSG Y C+A+N GS ++++V+ P D+P+
Sbjct: 1331 TIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPP---DQPR 1384
Score = 36.6 bits (83), Expect = 0.15
Identities = 62/290 (21%), Positives = 109/290 (37%), Gaps = 26/290 (8%)
Query: 628 PDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNS 687
P P ++ + V ++W+P N I Y V P V + P S +
Sbjct: 1189 PGPPAGVKAAAASASMVFVSWLPPLKLNGIIRKYTVFCSHPY--PTVISEFEASPDSFSY 1246
Query: 688 AVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEIT 747
+ LS Y V+A+ G + S + AP G T +I
Sbjct: 1247 RIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAKAPARILT--FSGTVTTPWMKDIV 1304
Query: 748 WTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQ----- 802
P A P VKW + ++ + VT+ G R + ++ ++ +
Sbjct: 1305 -LPCKAVGDPSP----AVKWMK-DSNGTPSLVTIDGRRSIFSNGS-FIIRTVKAEDSGYY 1357
Query: 803 ---AENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYT 859
A N++G E ++ + P PR V + +I L W ++ + GY
Sbjct: 1358 SCIANNNWGSD---EIILNLQVQVPPDQPR-LTVSKTTSSSITLSWLPGDNGGSSIRGYI 1413
Query: 860 LKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSG 909
L+Y N + G + SP++ + ++ + Y+FTL+A+ VG G
Sbjct: 1414 LQYSEDNSEQWGSFPI---SPSERSYRLENLKCGTWYKFTLTAQNGVGPG 1460
Score = 34.3 bits (77), Expect = 0.76
Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 4/81 (4%)
Query: 356 LVCRANGNPKPTVQWM--VNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNE 413
L C+A G+P P V+WM NG P + + I R + Y C +N
Sbjct: 1305 LPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNN 1364
Query: 414 HG--YLLANAFVSVLDVPPRM 432
G ++ N V V PR+
Sbjct: 1365 WGSDEIILNLQVQVPPDQPRL 1385
Score = 32.3 bits (72), Expect = 2.9
Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 16/110 (14%)
Query: 37 LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFN--IAKDPRVSMRR 94
LT T+T KD I++ C+A G+P+P+ W ++S + D R S+
Sbjct: 1289 LTFSGTVTTPWMKD--------IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFS 1340
Query: 95 RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPK 144
++ ++ E G Y C A N +G+ + LQV P P+
Sbjct: 1341 NGSFIIRTVKA-----EDSGYYSCIANNNWGSD-EIILNLQVQVPPDQPR 1384
>gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo
sapiens]
Length = 1386
Score = 184 bits (466), Expect = 6e-46
Identities = 151/512 (29%), Positives = 231/512 (45%), Gaps = 37/512 (7%)
Query: 18 LLSLGGAIEIPMDPSIQNELTQP----PTITKQSAKDHIVDPRDNILIECEAKGNPAPSF 73
L +L + P DPS+ P P I +Q D +V + + C A+G P P+
Sbjct: 37 LAALNHTLLPPGDPSLNGSRVGPEDAMPRIVEQPP-DLLVSRGEPATLPCRAEGRPRPNI 95
Query: 74 HWTRN-SRFFNIAKDPRVS-MRRRSGTLVID-FRSGGRPEEYEGEYQCFARNKFGTALSN 130
W +N +R + +DPR + SG L G R EG Y C ARN G A S
Sbjct: 96 EWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRRARPDEGVYTCVARNYLGAAASR 155
Query: 131 RIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVS 190
L+V+ +++ VVV G P L+C PP G P P + W ++ R++
Sbjct: 156 NASLEVAVLRDDFRQSPGNVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRIT 215
Query: 191 QGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQ 250
G L S+ + D Y C A ++ ++ +V+ V ER PSF+
Sbjct: 216 I-RGGKLMMSHTLKSDAGM-YVCVA----SNMAGERESAAAEVM----VLER-PSFLR-- 262
Query: 251 GTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEED 310
+Q+VL + C G P P + W K+ G+LP+ + + + + +L I +VS ED
Sbjct: 263 -RPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELPTGRYEIRS-DHSLWIGHVSAED 320
Query: 311 SGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 370
G Y C+A N +G + S+ V P + +P++ + APGE C GNP P + W
Sbjct: 321 EGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFW 380
Query: 371 MVNGE-----PLQSAPPNPNREVAG-DTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVS 424
G P QS P V+ + Q Y C + G +LA A +
Sbjct: 381 QKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAGSILAKALLE 440
Query: 425 V----LD-VPPRMLS-PRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNY 478
+ LD +PP +L P NQ + +L + L C G+P P++RW K+GQ D +
Sbjct: 441 IKGASLDGLPPVILQGPANQTL--VLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQF 498
Query: 479 HVYENGSLEIKMIRKEDQGIYTCVATNILGKA 510
NG+L I +++ D G Y+CVA + G+A
Sbjct: 499 KTMANGTLYIANVQEMDMGFYSCVAKSSTGEA 530
Score = 172 bits (435), Expect = 2e-42
Identities = 200/833 (24%), Positives = 328/833 (39%), Gaps = 97/833 (11%)
Query: 150 VVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPIT--QDKRVSQG--HNGDLYFSNVM-- 203
++V G P TL C G P P I W + T +D R + +G L+F ++
Sbjct: 73 LLVSRGEPATLPCRAE-GRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHG 131
Query: 204 --LQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRG 261
+ + Y+C AR ++ +N +L+V R ++P + +V G
Sbjct: 132 RRARPDEGVYTCVAR-NYLGAAASRNA-SLEVAVLRDDFRQSPG---------NVVVAVG 180
Query: 262 MDLLLECIAS-GVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASN 320
+LEC+ G P P ++W K G L ++ + L +++ + D+G Y C+ASN
Sbjct: 181 EPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDAGMYVCVASN 240
Query: 321 KMGSIRHTIS-VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQS 379
G + V V P +L P N ++ +C G+P P ++W L
Sbjct: 241 MAGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGEL-- 298
Query: 380 APPNPNREVAGD-TIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLS-PRN 437
P E+ D ++ Y C N G A+ +SV VPP++++ P++
Sbjct: 299 --PTGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSV-HVPPQLVTQPQD 355
Query: 438 QLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNL-------DGGNYHVYENGSLEIKM 490
Q+ C G+P P + W K G L G + V G L I
Sbjct: 356 QMAAP--GESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITA 413
Query: 491 IRKEDQGIYTCVATNILGKAENQVRLEVKD------PTRIYRMPEDQVARRGTTVQLECR 544
+++ D G Y C A ++ G + LE+K P I + P +Q G++V L CR
Sbjct: 414 VQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCR 473
Query: 545 VKHDPSLKLTVSWLKDDEPLYIGNRMKKE--DDSLTIFGVAERDQGSYTCVASTELDQDL 602
V +P + +V W KD + L + K + +L I V E D G Y+CVA + +
Sbjct: 474 VTGNP--QPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEAT 531
Query: 603 AKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYV 662
+L + D + P P P +T++ + S+ LTW P + +T YV
Sbjct: 532 WSGWLKMREDWGVSPDPPTE-PSSPPGAPSQPVVTEITKNSITLTWKPNPQTGAAVTSYV 590
Query: 663 VQFEEDQFQP---GVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSER 719
+ + F P W + V L P Y F V A+ G S PS SE
Sbjct: 591 I----EAFSPAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPVSEP 646
Query: 720 YRTSGAPPESNPGDVKGEGTR----------------KNNMEITWT---PMNATSAFGPN 760
RT + P S P + G + ++++WT P+ F
Sbjct: 647 VRTQDSSP-SRPVEDPWRGQQGLAEVAVRLQEPIVLGPRTLQVSWTVDGPVQLVQGFR-- 703
Query: 761 LRYIVKWR-RRETREAWNNVTVWG---SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESV 816
V WR +W + + V+ P +I+VQA+ G G E SV
Sbjct: 704 ----VSWRVAGPEGGSWTMLDLQSPSQQSTVLRGLPPGTQIQIKVQAQGQEGLGAESLSV 759
Query: 817 IGYSGEDLPSAPRR---FRVRQPNLETINLEWDH--PEHPNGIMIGYTLKYVAFNGTKVG 871
E+ PS P + + +I + W+ P NG++ Y + + G +
Sbjct: 760 TRSIPEEAPSGPPQGVAVALGGDGNSSITVSWEPPLPSQQNGVITEYQIWCL---GNESR 816
Query: 872 KQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSG---EAVTEESPAPPN 921
+ + + ++ P YR ++A T G G V + P+PP+
Sbjct: 817 FHLNRSAAGWARSAMLRGLVPGLLYRTLVAAATSAGVGVPSAPVLVQLPSPPD 869
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 181 bits (460), Expect = 3e-45
Identities = 164/596 (27%), Positives = 248/596 (41%), Gaps = 46/596 (7%)
Query: 40 PPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTR-NSRFFNIAKDPRVSMRRRSGT 98
PPTI D V +++ C + G PAP+ W++ ++ RVS SG
Sbjct: 2574 PPTIADDQT-DFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSP---SGA 2629
Query: 99 LVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLW-PKENLDPVVVQEGAP 157
L I G + G Y C ARN G A + L V SP+ P ++ V +E
Sbjct: 2630 LEI----GQALPIHAGRYTCSARNSAGVA-HKHVFLTVQASPVVKPLPSVVRAVAEEEVL 2684
Query: 158 LTLQCNPPPGLPSPVIFWMSSSMEPITQ-DKRVSQGHNGDLYFSNVMLQDMQTDYSCNAR 216
L + + G+P P I W + T +V G G L ++ +D +Y C A
Sbjct: 2685 LPCEAS---GIPRPTITWQKEGLNVATGVSTQVLPG--GQLRIAHASPEDAG-NYLCIA- 2737
Query: 217 FHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTP 276
KN + TR V + P + G L C A G P P
Sbjct: 2738 ---------KNSAGSAMGKTRLVVQVPPVI---ENGLPDLSTTEGSHAFLPCKARGSPEP 2785
Query: 277 DIAWYKKGGDLPSDKAKFE-NFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA 335
+I W K G + + KF + L + N+ +D+G Y C A N +G R + + +
Sbjct: 2786 NITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILV 2845
Query: 336 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIF 395
P + P + L G+ L C A G+P P + W VN P+ + + G T+
Sbjct: 2846 LPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGV---SEQDGGSTLQR 2902
Query: 396 RDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFF 455
Y C N G A +FV V + P + L+ + +LDC
Sbjct: 2903 AAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPV-GGSIQLDCVVR 2961
Query: 456 GSPIPTLRWFKNG---QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAEN 512
G P+P + W K+G +GS+L H +NGSL I+ ++D G Y C+A N +G A+
Sbjct: 2962 GDPVPDIHWIKDGLPLRGSHLR----HQLQNGSLTIRRTERDDAGRYQCLAENEMGVAKK 3017
Query: 513 QVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 572
V L ++ P+D R G V L C+ +P+ T+ WL+ +PL R++
Sbjct: 3018 VVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPT--PTIEWLQAGQPLRASRRLRT 3075
Query: 573 -EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGR 627
D SL + V D G+Y CVA L A+A+L V + + + GR
Sbjct: 3076 LPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSWGSMTGVINGR 3131
Score = 157 bits (398), Expect = 5e-38
Identities = 156/612 (25%), Positives = 255/612 (41%), Gaps = 58/612 (9%)
Query: 41 PTI---TKQSAKDHIVDPRDN-ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 96
PTI + SA + + +N I + CEA P+P+ W ++ F +++ ++ +
Sbjct: 1255 PTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQL-LPGTH 1313
Query: 97 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR-----IRLQVSKSPLWPKENLDPVV 151
G +++ + +E G+Y C N+ G A+ N I +SK + + V
Sbjct: 1314 GLQILNAQ-----KEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVK 1368
Query: 152 VQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDY 211
+ + LTL+C +P P I W +P+T R+ G L LQ T
Sbjct: 1369 TKVNSTLTLECESW-AVPPPTIRWYKDG-QPVTPSSRLQVLGEGRL------LQIQPTQV 1420
Query: 212 SCNARFHFTHT------------IQQKNPFTLKVLTTRGVAERTPSFMYPQGTASS-QMV 258
S + R+ T + Q P KV E +G + + +
Sbjct: 1421 SDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREI 1480
Query: 259 LRGMDLLLECIASGVPTPDIAWYKKGGDLPS-DKAKFENFNKALRITNVSEEDSGEYFCL 317
+ L C + +P PD+ WY++ L + D+ + L+I V E++G Y C
Sbjct: 1481 VENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCK 1540
Query: 318 ASNKMGSIRHTISVRVKAAPYWLDEPKNLI----LAPGEDGRLVCRANGNPKPTVQWMVN 373
ASN++G + V P L + + L+ + L C A GNP PT+ W+ N
Sbjct: 1541 ASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQN 1600
Query: 374 GEPLQSAPPNPNREVAGDTIIFR--DTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPR 431
G P P+P +V D + + +++ A Y C N+ G F + VPPR
Sbjct: 1601 GLPFS---PSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA-EKLFTLRVQVPPR 1656
Query: 432 MLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMI 491
+ + + IL + L C P P + W+K+ Q +L + + +L++
Sbjct: 1657 IAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRA 1716
Query: 492 RKEDQGIYTCVATNILGKAENQVRLEVKDP---TRIYRMPEDQV-ARRGTTVQLECRVKH 547
R D G+YTC A N G+ + V+L V P + R P+D V R G L C
Sbjct: 1717 RLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCET-- 1774
Query: 548 DPSLKLTVSWLKDDEPLYIGNRMK--KEDDSLTIFGVAERDQGSYTCVASTELDQDLAKA 605
D + TV+W KD +PL + R + + L I D+G Y+C S + +
Sbjct: 1775 DALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTF 1834
Query: 606 YLTVLADQATPT 617
LTV Q PT
Sbjct: 1835 TLTV---QVPPT 1843
Score = 156 bits (394), Expect = 1e-37
Identities = 152/563 (26%), Positives = 234/563 (41%), Gaps = 70/563 (12%)
Query: 57 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYE--- 113
D ++ CE P P+ W ++ + P V +R R G R E E
Sbjct: 1766 DKAVLSCETDALPEPTVTWYKDGQ-------PLVLAQRTQA-----LRGGQRLEIQEAQV 1813
Query: 114 ---GEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPS 170
G Y C N G A+ L V P + + V G+PL L C+ G+P+
Sbjct: 1814 SDKGLYSCKVSNVAGEAVRT-FTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVS-GVPA 1871
Query: 171 PVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFT 230
P + W+ M + G L S + T Y+C A + + F
Sbjct: 1872 PTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGT-YTCVAE---NTQAEARKDFV 1927
Query: 231 LKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD 290
+ VL VA R S G A VL G ++ L+C A G P PD+AW K G L D
Sbjct: 1928 VAVL----VAPRIRS----SGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQD 1979
Query: 291 KAKFENF---NKALRITNVSEEDSGEYFCLASNKMG--SIRHTISVRV-KAAPYWLDEPK 344
F +L + + D+G Y C+A N G + HT++V V D
Sbjct: 1980 MGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSG 2039
Query: 345 NLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV---AGDTIIFRDTQIS 401
L+ PGE +VC G+P V W+ +G PL P R + +G T+ Q++
Sbjct: 2040 TLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPL----PLSQRTLLHGSGHTLRISKVQLA 2095
Query: 402 SRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSP---RNQLIRVILYNRTRLDCPFFGSP 458
++ C ++ G N F + VPP +L P +N ++ V+ + L C G P
Sbjct: 2096 DAGIFTCVAASPAGVADRN-FTLQVQVPP-VLEPVEFQNDVV-VVRGSLVELPCEARGVP 2152
Query: 459 IPTLRWFKNGQ---GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR 515
+P + W K+G+ +L+ G SL+++ + D G Y+CVA + G+A +
Sbjct: 2153 LPLVSWMKDGEPLLSQSLEQG-------PSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQ 2205
Query: 516 LEVKDPTRI--YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKE 573
L V +P I P + G ++L C + P +T W KD + L + E
Sbjct: 2206 LTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNIT--WHKDGQAL-----TRLE 2258
Query: 574 DDSLTIFGVAERDQGSYTCVAST 596
++S + RD G YTC+A +
Sbjct: 2259 NNSRATRVLRVRDAGLYTCLAES 2281
Score = 154 bits (389), Expect = 5e-37
Identities = 168/695 (24%), Positives = 262/695 (37%), Gaps = 80/695 (11%)
Query: 37 LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 96
L P + A++H V + ++CEA G P P W ++ P +
Sbjct: 1931 LVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDG 1990
Query: 97 GTLVIDFRSGGRPEEYEGEYQCFARNKFG-TALSNRIRLQVSKSPLWPKENLDPVVVQEG 155
G+LV+ G G Y C A N G A + + + V + + +V + G
Sbjct: 1991 GSLVLK----GLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPG 2046
Query: 156 APLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNA 215
+T+ C P G P + W+ + + + G L S V L D ++C A
Sbjct: 2047 ELVTMVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGI-FTCVA 2104
Query: 216 RFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPT 275
+ +N FTL+V + P + P + +V+RG + L C A GVP
Sbjct: 2105 A--SPAGVADRN-FTLQV--------QVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPL 2153
Query: 276 PDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA 335
P ++W K G L S + +L++ V DSG Y C+A ++ G R + V
Sbjct: 2154 PLVSWMKDGEPLLSQSLE---QGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVME 2210
Query: 336 APYWLD--EPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTI 393
P+ D +P L L PG L+C A G P+P + W +G+ L N
Sbjct: 2211 PPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRAT------ 2264
Query: 394 IFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNRTRLDC 452
R ++ +Y C + G + +F + PP ++ PR + + + + L+C
Sbjct: 2265 --RVLRVRDAGLYTCLAESPAG-AIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLEC 2321
Query: 453 PFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAEN 512
P P + W ++G D L+++ + D G Y+C A N G
Sbjct: 2322 SVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSV 2381
Query: 513 QVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 572
R+E+ I P T L C+ P+ VSW KD PL + +
Sbjct: 2382 AFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPA--PLVSWRKDRVPLDPRSPRFE 2439
Query: 573 --EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDR 630
+ SL I V +D G Y C+AS D L VL P
Sbjct: 2440 ILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLE------------PPAIAPS 2487
Query: 631 PRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGV--WHDHSKYPGSVNSA 688
P +L LT + +P +A+ SP +P V W D K +
Sbjct: 2488 PSNLTLT-----AHTPALLPCEASGSP-------------KPLVVWWKDGQKLDFRLQQG 2529
Query: 689 VLRL-----------SPYVNYQFRVIAINEVGSSH 712
RL P + QF + NEVG +H
Sbjct: 2530 AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAH 2564
Score = 151 bits (382), Expect = 3e-36
Identities = 149/571 (26%), Positives = 230/571 (40%), Gaps = 37/571 (6%)
Query: 40 PPTI---TKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 96
PP I T++ ++ V+ + ++C A GNP P+ W +N F+ PR+ +
Sbjct: 1559 PPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFS--PSPRLQVLEDG 1616
Query: 97 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGA 156
L + Y C A N+ G+A L+V P +L+ V +
Sbjct: 1617 QVLQVSTAEVADA----ASYMCVAENQAGSA-EKLFTLRVQVPPRIAGLDLEQVTAILNS 1671
Query: 157 PLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNAR 216
++L C+ P+P + W S ++ L L D Y+C A
Sbjct: 1672 SVSLPCDVHAH-PNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGM-YTCEA- 1728
Query: 217 FHFTHTIQQKNPFTLKVLTTRGVAERTPSFMY-PQGTASSQMVLRGMDLLLECIASGVPT 275
+ + L VL P+F P+G + +V G +L C +P
Sbjct: 1729 --LNAAGRDQKLVQLSVLVP-------PAFRQAPRGPQDAVLVRVGDKAVLSCETDALPE 1779
Query: 276 PDIAWYKKGGDLP-SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVK 334
P + WYK G L + + + + L I D G Y C SN G T ++ V+
Sbjct: 1780 PTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ 1839
Query: 335 AAPYWLDEPKNLILA--PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT 392
P + + PK ++ G L C +G P PTV W+ + P++S+ + G
Sbjct: 1840 VPPTF-ENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRL 1898
Query: 393 IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDC 452
+ R Q + Y C N + V+VL P S + V+ RLDC
Sbjct: 1899 QLSR-LQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDC 1957
Query: 453 PFFGSPIPTLRWFKNGQGSNLDGGNY--HVYENGSLEIKMIRKEDQGIYTCVATNILGKA 510
G P P + W K+G D G + + GSL +K +R D G YTCVA N G+
Sbjct: 1958 EADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGED 2017
Query: 511 ENQVRLEVKDPTRIYRMPEDQ---VARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIG 567
+ V P I + + V+R G V + C V+ P + VSWLKD PL +
Sbjct: 2018 ARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIH--VSWLKDGLPLPLS 2075
Query: 568 NR--MKKEDDSLTIFGVAERDQGSYTCVAST 596
R + +L I V D G +TCVA++
Sbjct: 2076 QRTLLHGSGHTLRISKVQLADAGIFTCVAAS 2106
Score = 150 bits (379), Expect = 7e-36
Identities = 148/591 (25%), Positives = 237/591 (40%), Gaps = 52/591 (8%)
Query: 40 PPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTL 99
PP IT + V + + C A G P+P+ W ++ + A P + + L
Sbjct: 694 PPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVL 753
Query: 100 VIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLD-PVVVQEGAPL 158
+ + R + G Y C A + G + + LQV P E L+ VV E L
Sbjct: 754 TL---ASARASD-SGRYSCVAVSAVGEDRQDVV-LQVHMPPSILGEELNVSVVANESVAL 808
Query: 159 TLQCNPPPGLPSPVIFWMSSS--MEP-----ITQDKRVSQGHNGDLYFSNVMLQDMQTDY 211
Q + +P PV+ W +EP ++ DK + Q D++ + Y
Sbjct: 809 ECQSH---AMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAG--------HY 857
Query: 212 SCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIAS 271
+C A H+ + N L V ++P + + V G L C
Sbjct: 858 TCEALNQAGHSEKHYN---LNVWVAP---------VFPLRESHTLTVREGHPTRLSCECR 905
Query: 272 GVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEED---SGEYFCLASNKMGSIRHT 328
GVP P I+W K G LP + A ++ + R+ + + G Y C SN +G+
Sbjct: 906 GVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQD 965
Query: 329 ISVRVKAAPYWL---DEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPN 385
+ + V P + P + + L C A G P PTV W +G+P+ A
Sbjct: 966 LQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPV-GAELGLQ 1024
Query: 386 REVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQL--IRVI 443
+ G ++ Q + Y C N G +SVL VPP ++ + L I
Sbjct: 1025 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVL-VPPELIGDLDPLTNITAA 1083
Query: 444 LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 503
L++ L C G P P +RWF+ + + Y + L++ +++D G+Y+C+A
Sbjct: 1084 LHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLA 1143
Query: 504 TNILGKAENQVRLEVKDPTRIYRMPEDQVAR--RGTTVQLECRVKHDPSLKLTVSWLKDD 561
+N G+A +EV P I ++V + G T L C V P KLT W KD
Sbjct: 1144 SNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLT--WFKDG 1201
Query: 562 EPLYIGNRMKKEDDS--LTIFGVAERDQGSYTCVASTELDQDLAKAYLTVL 610
PL G+ D L + G Y+C+A+ + + L+VL
Sbjct: 1202 RPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVL 1252
Score = 150 bits (378), Expect = 9e-36
Identities = 160/613 (26%), Positives = 236/613 (38%), Gaps = 50/613 (8%)
Query: 34 QNELTQPPTITKQSAKDHI-VDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSM 92
Q + +PP I + + P + + C+A+G P P+ W ++ + R+
Sbjct: 2205 QLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALT-----RLEN 2259
Query: 93 RRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTA-LSNRIRLQVSKSPLWPKENLDPVV 151
R+ T V+ R G Y C A + G S R+R+Q + + P+ V
Sbjct: 2260 NSRA-TRVLRVRDAGL-------YTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVG 2311
Query: 152 VQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDY 211
+ G L L+C+ P+P I W + + +D G + DY
Sbjct: 2312 LAPGQ-LVLECSVEAE-PAPKITWHRDGIV-LQEDAHTQFPERGRFLQLQALSTADSGDY 2368
Query: 212 SCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIAS 271
SC AR T F +++ T + P+ V LL C A
Sbjct: 2369 SCTARNAAGST---SVAFRVEIHTVPTIRSGPPAVN----------VSVNQTALLPCQAD 2415
Query: 272 GVPTPDIAWYKKGGDLPSDKAKFENFNK-ALRITNVSEEDSGEYFCLASNKMGSIRHTIS 330
GVP P ++W K L +FE + +LRI V +D+G Y CLASN GS R
Sbjct: 2416 GVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRD 2475
Query: 331 VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQ-SAPPNPNREVA 389
+RV P P NL L L C A+G+PKP V W +G+ L R +
Sbjct: 2476 LRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLP 2535
Query: 390 GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTR 449
+ ++ A ++C SNE G + + VPP + + V +
Sbjct: 2536 SNALLLTAPGPQDSAQFECVVSNEVGE-AHRLYQVTVHVPPTIADDQTD-FTVTMMAPVV 2593
Query: 450 LDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGK 509
L C G P PT+ W K G G Y V +G+LEI G YTC A N G
Sbjct: 2594 LTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGV 2653
Query: 510 AENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIG-N 568
A V L V+ + +P A V L C P + T++W K+ + G +
Sbjct: 2654 AHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIP--RPTITWQKEGLNVATGVS 2711
Query: 569 RMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV---------LADQATPTNR 619
L I + D G+Y C+A + K L V L D +T
Sbjct: 2712 TQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGS 2771
Query: 620 LAALP---KGRPD 629
A LP +G P+
Sbjct: 2772 HAFLPCKARGSPE 2784
Score = 144 bits (364), Expect = 4e-34
Identities = 146/562 (25%), Positives = 225/562 (40%), Gaps = 45/562 (8%)
Query: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
+ CE +G P P W ++ + + + G L+ G EG Y C
Sbjct: 900 LSCECRGVPFPKISWRKDGQPLP-GEGAGLQHVSAVGRLLY---LGQAQLAQEGTYTCEC 955
Query: 121 RNKFGTALSNRIRLQVSKSP--LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSS 178
N G + S ++L+V P P+E V V + TL+CN G P P + W
Sbjct: 956 SNVVGNS-SQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNAT-GKPPPTVTWERD 1013
Query: 179 SMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRG 238
+P+ + + + G YSC A + ++K F L VL
Sbjct: 1014 G-QPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAE-NLAGRAERK--FELSVLVP-- 1067
Query: 239 VAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL-PSDKAKFENF 297
P + ++ L L C A G+P P I W++ + P +
Sbjct: 1068 -----PELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAG 1122
Query: 298 NKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA--PGEDGR 355
L++T E+DSG Y CLASN+ G R SV V P +E ++ G+
Sbjct: 1123 GWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAH 1182
Query: 356 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQ--ISSRAVYQCNTSNE 413
L+C G+P+P + W +G PL + ++ D ++ + Q +SS Y C +N
Sbjct: 1183 LMCNVTGHPQPKLTWFKDGRPLARGDAH---HISPDGVLLQVLQANLSSAGHYSCIAANA 1239
Query: 414 HGYLLANAFVSVLDVPPRMLSPRNQL---IRVILYNRTRLDCPFFGSPIPTLRWFKNGQG 470
G + +SVL P + + + V + N L C P P + W K+G
Sbjct: 1240 VGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAP 1299
Query: 471 SNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPED 530
+ L+I +KED G YTCV TN LG+A +EV P I + +D
Sbjct: 1300 FEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISK--DD 1357
Query: 531 QVARRG---------TTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK--KEDDSLTI 579
+A G +T+ LEC P T+ W KD +P+ +R++ E L I
Sbjct: 1358 PLAEVGVKEVKTKVNSTLTLECESWAVP--PPTIRWYKDGQPVTPSSRLQVLGEGRLLQI 1415
Query: 580 FGVAERDQGSYTCVASTELDQD 601
D G Y CVA+ +D
Sbjct: 1416 QPTQVSDSGRYLCVATNVAGED 1437
Score = 140 bits (354), Expect = 6e-33
Identities = 156/628 (24%), Positives = 253/628 (40%), Gaps = 86/628 (13%)
Query: 33 IQNELTQPPTIT-KQSAKDHIVDPRDNIL-IECEAKGNPAPSFHWTRNSRFFNIAKDPRV 90
+Q E+ PP I + + +D + +EC A G P P+ W R+ + + + +
Sbjct: 966 LQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQ--PVGAELGL 1023
Query: 91 SMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKE---NL 147
++ + +L ++ + G Y C A N L+ R + S L P E +L
Sbjct: 1024 QLQNQGQSLHVERAQAA----HTGRYSCVAEN-----LAGRAERKFELSVLVPPELIGDL 1074
Query: 148 DPVVVQEGA---PLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVML 204
DP+ A PLTL C G+P P I W EP VS G + L ML
Sbjct: 1075 DPLTNITAALHSPLTLLCEAM-GIPPPAIRWFRGE-EP------VSPGEDTYLLAGGWML 1126
Query: 205 QDMQTD------YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMV 258
+ QT YSC A + + F+++VL P + + V
Sbjct: 1127 KMTQTQEQDSGLYSCLAS---NEAGEARRNFSVEVLV--------PPSIENEDLEEVIKV 1175
Query: 259 LRGMDLLLECIASGVPTPDIAWYKKGGDLP-SDKAKFENFNKALRITNVSEEDSGEYFCL 317
L G L C +G P P + W+K G L D L++ + +G Y C+
Sbjct: 1176 LDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCI 1235
Query: 318 ASNKMGSIRHTISVRVKAAPYWL-----DEPKNLILAPGEDGRLVCRANGNPKPTVQWMV 372
A+N +G + V AP L + + + L+C A P P + WM
Sbjct: 1236 AANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMK 1295
Query: 373 NGEPLQSAPPNPNREVAGDT--IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPP 430
+G P +++ N ++ T + + Q Y C +NE G + N V VL +PP
Sbjct: 1296 DGAPFEASR---NIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVL-IPP 1351
Query: 431 RMLS--PRNQL----IRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENG 484
+ P ++ ++ + + L+C + P PT+RW+K+GQ + E
Sbjct: 1352 SISKDDPLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGR 1411
Query: 485 SLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYR----------MPEDQVAR 534
L+I+ + D G Y CVATN+ G+ + + ++ P + + ++ AR
Sbjct: 1412 LLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEAR 1471
Query: 535 RGTT----------VQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK--KEDDSLTIFGV 582
G T L C P LT W ++D+PL G+ + + L I V
Sbjct: 1472 GGVTEYREIVENNPAYLYCDTNAIPPPDLT--WYREDQPLSAGDEVSVLQGGRVLQIPLV 1529
Query: 583 AERDQGSYTCVASTELDQDLAKAYLTVL 610
+ G Y+C AS E+ +D L VL
Sbjct: 1530 RAENAGRYSCKASNEVGEDWLHYELLVL 1557
Score = 137 bits (344), Expect = 8e-32
Identities = 126/505 (24%), Positives = 206/505 (40%), Gaps = 31/505 (6%)
Query: 30 DPSIQNELTQPPTITKQSAKDHIVDPR-DNILIECEAKGNPAPSFHWTRNSRFFNIAKDP 88
+P + PP+I + K ++ ++ +EC+A G P P W ++++ +
Sbjct: 6 EPLLNTGSVVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGW 65
Query: 89 R-----VSMRRRSGTLVIDF-RSGGRPEEYEGE---YQCFARNKFGTALSNRIRLQVSKS 139
+ + G ++D +S P EG+ Y C A N+ GTA + L ++
Sbjct: 66 AGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPP 125
Query: 140 PLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYF 199
+ V+ GA + LQC G+P+P + W + + +G +
Sbjct: 126 SVLGAGAAQEVLGLAGADVELQCWTS-GVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLR 184
Query: 200 SNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVL 259
+ Y C A F+ QQ F L+V P ++ V+
Sbjct: 185 ITGSHVGDEGRYQCVA---FSPAGQQARDFQLRV--------HAPPTIWGSNETGEVAVM 233
Query: 260 RGMDLLLECIASGVPTPDIAWYKKGGDLP-SDKAKFENFNKALRITNVSEEDSGEYFCLA 318
+ L C A GVPTP+I W+K G LP S K + + L++ D+G Y C A
Sbjct: 234 EDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKA 293
Query: 319 SNKMGSIRHTISVRVKAAPYWLD---EPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGE 375
SN +G+ + V P P + G L C A G+P PT+ W G
Sbjct: 294 SNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGL 353
Query: 376 PLQSAPPNPNR-EVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLS 434
P+ A N +R E G + +S +Y C S+ G + V V VPP++L
Sbjct: 354 PV--AESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEV-QVPPQLLV 410
Query: 435 PRNQ-LIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRK 493
+ I+ L C GSP+PT++W +NG+ + G + +L I +
Sbjct: 411 AEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVEL 470
Query: 494 EDQGIYTCVATNILGKAENQVRLEV 518
+ G++ C ATN G A +V + V
Sbjct: 471 DHSGLFACQATNEAGTAGAEVEVSV 495
Score = 133 bits (334), Expect = 1e-30
Identities = 153/607 (25%), Positives = 231/607 (38%), Gaps = 88/607 (14%)
Query: 25 IEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNI 84
+++P + L Q TI Q + + C+A G+P P+ W +N R
Sbjct: 402 VQVPPQLLVAEGLGQVTTIVGQPLE-----------LPCQASGSPVPTIQWLQNGR--PA 448
Query: 85 AKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPK 144
+ V + + TL ID ++ G + C A N+ GTA + ++VS W
Sbjct: 449 EELAGVQVASQGTTLHIDHVE----LDHSGLFACQATNEAGTAGAE---VEVSVHGEWAP 501
Query: 145 ENLDPVVVQ------EGAPLTLQCNPP--------------PGLPSPVIFWMSSSMEPIT 184
L+ + Q + C+PP G SP W + P
Sbjct: 502 GVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIP-- 559
Query: 185 QDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTP 244
V+ L V L+D + Y+C A + K LKVL +
Sbjct: 560 ----VAYSLPPPLQIEKVDLRD-EGIYTCAAT---NLAGESKREVALKVLVPPNI----- 606
Query: 245 SFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFN-KALRI 303
+ ++ VL + LEC+ASGVP PD++W+K + S + + + LRI
Sbjct: 607 -----EPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRI 661
Query: 304 TNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDG--------R 355
D+G Y C+ASN GS +RV P + L P G R
Sbjct: 662 EQAQLSDAGSYRCVASNVAGSTELRYGLRVNV-------PPRITLPPSLPGPVLVNTPVR 714
Query: 356 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTIIFRDTQISSRAVYQCNTSNE 413
L C A G P PT+ W+ +G P+ A P +V G + + S Y C +
Sbjct: 715 LTCNATGAPSPTLMWLKDGNPVSPA-GTPGLQVFPGGRVLTLASARASDSGRYSCVAVSA 773
Query: 414 HGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNL 473
G + + V +PP +L + V+ L+C P P L W+K+G+
Sbjct: 774 VGEDRQDVVLQV-HMPPSILGEELN-VSVVANESVALECQSHAMPPPVLSWWKDGRPLEP 831
Query: 474 DGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV-KDPTRIYRMPEDQV 532
G + + L++ D G YTC A N G +E L V P R
Sbjct: 832 RPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLT 891
Query: 533 ARRGTTVQLECRVKHDPSLKLTVSWLKDDEPL---YIGNRMKKEDDSLTIFGVAE-RDQG 588
R G +L C + P K +SW KD +PL G + L G A+ +G
Sbjct: 892 VREGHPTRLSCECRGVPFPK--ISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEG 949
Query: 589 SYTCVAS 595
+YTC S
Sbjct: 950 TYTCECS 956
Score = 122 bits (306), Expect = 2e-27
Identities = 103/378 (27%), Positives = 159/378 (42%), Gaps = 29/378 (7%)
Query: 244 PSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK-------------GGDLPSD 290
P + G ++ + G L LEC A+G P P+I W K G DL
Sbjct: 16 PPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWG 75
Query: 291 KA---KFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDE--PKN 345
+ + + ++L + E DSG Y C A N+ G+ + + V P L +
Sbjct: 76 QVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQE 135
Query: 346 LILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAV 405
++ G D L C +G P P V+W + +P+ P+ + G + + +
Sbjct: 136 VLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGR 195
Query: 406 YQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWF 465
YQC + G + + V P S + V+ + +L C G P P + WF
Sbjct: 196 YQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWF 255
Query: 466 KNGQGSNLDGGNYHVYENGSLEIKMIRKE--DQGIYTCVATNILGKAENQVRLEVKDPTR 523
K+G + L VY G ++++ R + D G+YTC A+N +G AE RL+V P
Sbjct: 256 KDG--ALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPT 313
Query: 524 IY---RMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDS--LT 578
I P A G V LEC + PS T+SW + P+ N + E D L
Sbjct: 314 IEGAGGRPYVVKAVAGRPVALECVARGHPS--PTLSWHHEGLPVAESNESRLETDGSVLR 371
Query: 579 IFGVAERDQGSYTCVAST 596
+ E G Y+CVAS+
Sbjct: 372 LESPGEASSGLYSCVASS 389
Score = 119 bits (298), Expect = 2e-26
Identities = 102/396 (25%), Positives = 173/396 (43%), Gaps = 32/396 (8%)
Query: 37 LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 96
+ Q P + + D + + C+A+G+P P+ W ++ + + A+ + S
Sbjct: 2751 VVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTI--QPS 2808
Query: 97 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGA 156
G L++ G + G Y C A N G A R+ L + P++ D + + G
Sbjct: 2809 GELLVKNLEG----QDAGTYTCTAENAVGRA-RRRVHLTILVLPVFTTLPGDRSL-RLGD 2862
Query: 157 PLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNA- 215
L L+C G P+P I W + P+T+ VS+ G + ++ Y C A
Sbjct: 2863 RLWLRC-AARGSPTPRIGWTVND-RPVTEG--VSEQDGGSTLQRAAVSREDSGTYVCWAE 2918
Query: 216 -RFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLR-GMDLLLECIASGV 273
R T + + VL QG A S +V G + L+C+ G
Sbjct: 2919 NRVGRTQAVSFVHVKEAPVL---------------QGEAFSYLVEPVGGSIQLDCVVRGD 2963
Query: 274 PTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRV 333
P PDI W K G L + + N +L I +D+G Y CLA N+MG + + + +
Sbjct: 2964 PVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAENEMGVAKKVVILVL 3023
Query: 334 KAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTI 393
++AP + EP+++ + G+D L C+A G P PT++W+ G+PL+++ R + ++
Sbjct: 3024 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRAS--RRLRTLPDGSL 3081
Query: 394 IFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVP 429
+ + Y C N G A AF+ V P
Sbjct: 3082 WLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEP 3117
Score = 111 bits (278), Expect = 4e-24
Identities = 126/486 (25%), Positives = 199/486 (40%), Gaps = 44/486 (9%)
Query: 155 GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNV----MLQDMQTD 210
G LTL+C+ G P P I W+ + + G+ DL + V +L + Q+
Sbjct: 33 GQSLTLECDAN-GFPVPEIVWLKDAQ--LVGVPLGWAGYGWDLGWGQVGGHRLLDEGQS- 88
Query: 211 YSCNARFHFTHTIQQKNP--FTLKVLTTRGVAER-------TPSFMYPQGTASSQMVLRG 261
HF IQ+ + ++ + G A+R TP + G A + L G
Sbjct: 89 ------LHFPR-IQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAG 141
Query: 262 MDLLLECIASGVPTPDIAWYK-KGGDLPSDK-AKFENFNKALRITNVSEEDSGEYFCLAS 319
D+ L+C SGVPTP + W K + LP + + + LRIT D G Y C+A
Sbjct: 142 ADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAF 201
Query: 320 NKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDG--RLVCRANGNPKPTVQWMVNGEPL 377
+ G +RV A P + +A ED +L+C A G P P + W +G L
Sbjct: 202 SPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALL 261
Query: 378 QSAPPNPNREV---AGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRM-- 432
P + V G + Q S VY C SN G + V VPP +
Sbjct: 262 ----PTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVY-VPPTIEG 316
Query: 433 LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIR 492
R +++ + L+C G P PTL W G + + L ++
Sbjct: 317 AGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPG 376
Query: 493 KEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE-DQVAR-RGTTVQLECRVKHDPS 550
+ G+Y+CVA++ G+A Q +EV+ P ++ QV G ++L C+ P
Sbjct: 377 EASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSP- 435
Query: 551 LKLTVSWLKDDEPL--YIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLT 608
T+ WL++ P G ++ + +L I V G + C A+ E A+ ++
Sbjct: 436 -VPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVS 494
Query: 609 VLADQA 614
V + A
Sbjct: 495 VHGEWA 500
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 180 bits (457), Expect = 7e-45
Identities = 164/596 (27%), Positives = 247/596 (41%), Gaps = 46/596 (7%)
Query: 40 PPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTR-NSRFFNIAKDPRVSMRRRSGT 98
PPTI D V +++ C + G PAP+ W++ ++ RVS SG
Sbjct: 2665 PPTIADDQT-DFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSP---SGA 2720
Query: 99 LVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLW-PKENLDPVVVQEGAP 157
L I G + G Y C ARN G A + L V SP+ P ++ V +E
Sbjct: 2721 LEI----GQALPIHAGRYTCSARNSAGVA-HKHVFLTVQASPVVKPLPSVVRAVAEEEVL 2775
Query: 158 LTLQCNPPPGLPSPVIFWMSSSMEPITQ-DKRVSQGHNGDLYFSNVMLQDMQTDYSCNAR 216
L + + G+P P I W + T +V G G L ++ +D +Y C A
Sbjct: 2776 LPCEAS---GIPRPTITWQKEGLNVATGVSTQVLPG--GQLRIAHASPEDAG-NYLCIA- 2828
Query: 217 FHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTP 276
KN + TR V + P + G L C A G P P
Sbjct: 2829 ---------KNSAGSAMGKTRLVVQVPPVI---ENGLPDLSTTEGSHAFLPCKARGSPEP 2876
Query: 277 DIAWYKKGGDLPSDKAKFE-NFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA 335
+I W K G + + KF + L + N+ +D+G Y C A N +G R + + +
Sbjct: 2877 NITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILV 2936
Query: 336 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIF 395
P + P + L G+ L C A G+P P + W VN P+ + + G T+
Sbjct: 2937 LPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGV---SEQDGGSTLQR 2993
Query: 396 RDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFF 455
Y C N G A +FV V + P + L+ + +LDC
Sbjct: 2994 AAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPV-GGSIQLDCVVR 3052
Query: 456 GSPIPTLRWFKNG---QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAEN 512
G P+P + W K+G +GS+L H +NGSL I ++D G Y C+A N +G A+
Sbjct: 3053 GDPVPDIHWIKDGLPLRGSHLR----HQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKK 3108
Query: 513 QVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 572
V L ++ P+D R G V L C+ +P+ T+ WL+ +PL R++
Sbjct: 3109 VVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPT--PTIEWLQAGQPLRASRRLRT 3166
Query: 573 -EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGR 627
D SL + V D G+Y CVA L A+A+L V + + + GR
Sbjct: 3167 LPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSWGSMTGVINGR 3222
Score = 157 bits (397), Expect = 6e-38
Identities = 156/612 (25%), Positives = 255/612 (41%), Gaps = 58/612 (9%)
Query: 41 PTI---TKQSAKDHIVDPRDN-ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 96
PTI + SA + + +N I + CEA P+P+ W ++ F +++ ++ +
Sbjct: 1346 PTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQL-LPGTH 1404
Query: 97 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR-----IRLQVSKSPLWPKENLDPVV 151
G +++ + +E G+Y C N+ G A+ N I +SK + + V
Sbjct: 1405 GLQILNAQ-----KEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVK 1459
Query: 152 VQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDY 211
+ + LTL+C +P P I W +P+T R+ G L LQ T
Sbjct: 1460 TKVNSTLTLECESW-AVPPPTIRWYKDG-QPVTPSSRLQVLGEGRL------LQIQPTQV 1511
Query: 212 SCNARFHFTHT------------IQQKNPFTLKVLTTRGVAERTPSFMYPQGTASS-QMV 258
S + R+ T + Q P KV E +G + + +
Sbjct: 1512 SDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREI 1571
Query: 259 LRGMDLLLECIASGVPTPDIAWYKKGGDLPS-DKAKFENFNKALRITNVSEEDSGEYFCL 317
+ L C + +P PD+ WY++ L + D+ + L+I V E++G Y C
Sbjct: 1572 VENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCK 1631
Query: 318 ASNKMGSIRHTISVRVKAAPYWLDEPKNLI----LAPGEDGRLVCRANGNPKPTVQWMVN 373
ASN++G + V P L + + L+ + L C A GNP PT+ W+ N
Sbjct: 1632 ASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQN 1691
Query: 374 GEPLQSAPPNPNREVAGDTIIFR--DTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPR 431
G P P+P +V D + + +++ A Y C N+ G F + VPPR
Sbjct: 1692 GLPFS---PSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA-EKLFTLRVQVPPR 1747
Query: 432 MLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMI 491
+ + + IL + L C P P + W+K+ Q +L + + +L++
Sbjct: 1748 IAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRA 1807
Query: 492 RKEDQGIYTCVATNILGKAENQVRLEVKDP---TRIYRMPEDQV-ARRGTTVQLECRVKH 547
R D G+YTC A N G+ + V+L V P + R P+D V R G L C
Sbjct: 1808 RLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCET-- 1865
Query: 548 DPSLKLTVSWLKDDEPLYIGNRMK--KEDDSLTIFGVAERDQGSYTCVASTELDQDLAKA 605
D + TV+W KD +PL + R + + L I D+G Y+C S + +
Sbjct: 1866 DALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTF 1925
Query: 606 YLTVLADQATPT 617
LTV Q PT
Sbjct: 1926 TLTV---QVPPT 1934
Score = 156 bits (394), Expect = 1e-37
Identities = 152/563 (26%), Positives = 234/563 (41%), Gaps = 70/563 (12%)
Query: 57 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYE--- 113
D ++ CE P P+ W ++ + P V +R R G R E E
Sbjct: 1857 DKAVLSCETDALPEPTVTWYKDGQ-------PLVLAQRTQA-----LRGGQRLEIQEAQV 1904
Query: 114 ---GEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPS 170
G Y C N G A+ L V P + + V G+PL L C+ G+P+
Sbjct: 1905 SDKGLYSCKVSNVAGEAVRT-FTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVS-GVPA 1962
Query: 171 PVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFT 230
P + W+ M + G L S + T Y+C A + + F
Sbjct: 1963 PTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGT-YTCVAE---NTQAEARKDFV 2018
Query: 231 LKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD 290
+ VL VA R S G A VL G ++ L+C A G P PD+AW K G L D
Sbjct: 2019 VAVL----VAPRIRS----SGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQD 2070
Query: 291 KAKFENF---NKALRITNVSEEDSGEYFCLASNKMG--SIRHTISVRV-KAAPYWLDEPK 344
F +L + + D+G Y C+A N G + HT++V V D
Sbjct: 2071 MGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSG 2130
Query: 345 NLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV---AGDTIIFRDTQIS 401
L+ PGE +VC G+P V W+ +G PL P R + +G T+ Q++
Sbjct: 2131 TLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPL----PLSQRTLLHGSGHTLRISKVQLA 2186
Query: 402 SRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSP---RNQLIRVILYNRTRLDCPFFGSP 458
++ C ++ G N F + VPP +L P +N ++ V+ + L C G P
Sbjct: 2187 DAGIFTCVAASPAGVADRN-FTLQVQVPP-VLEPVEFQNDVV-VVRGSLVELPCEARGVP 2243
Query: 459 IPTLRWFKNGQ---GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR 515
+P + W K+G+ +L+ G SL+++ + D G Y+CVA + G+A +
Sbjct: 2244 LPLVSWMKDGEPLLSQSLEQG-------PSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQ 2296
Query: 516 LEVKDPTRI--YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKE 573
L V +P I P + G ++L C + P +T W KD + L + E
Sbjct: 2297 LTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNIT--WHKDGQAL-----TRLE 2349
Query: 574 DDSLTIFGVAERDQGSYTCVAST 596
++S + RD G YTC+A +
Sbjct: 2350 NNSRATRVLRVRDAGLYTCLAES 2372
Score = 154 bits (389), Expect = 5e-37
Identities = 168/695 (24%), Positives = 262/695 (37%), Gaps = 80/695 (11%)
Query: 37 LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 96
L P + A++H V + ++CEA G P P W ++ P +
Sbjct: 2022 LVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDG 2081
Query: 97 GTLVIDFRSGGRPEEYEGEYQCFARNKFG-TALSNRIRLQVSKSPLWPKENLDPVVVQEG 155
G+LV+ G G Y C A N G A + + + V + + +V + G
Sbjct: 2082 GSLVLK----GLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPG 2137
Query: 156 APLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNA 215
+T+ C P G P + W+ + + + G L S V L D ++C A
Sbjct: 2138 ELVTMVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGI-FTCVA 2195
Query: 216 RFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPT 275
+ +N FTL+V + P + P + +V+RG + L C A GVP
Sbjct: 2196 A--SPAGVADRN-FTLQV--------QVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPL 2244
Query: 276 PDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA 335
P ++W K G L S + +L++ V DSG Y C+A ++ G R + V
Sbjct: 2245 PLVSWMKDGEPLLSQSLE---QGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVME 2301
Query: 336 APYWLD--EPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTI 393
P+ D +P L L PG L+C A G P+P + W +G+ L N
Sbjct: 2302 PPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRAT------ 2355
Query: 394 IFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNRTRLDC 452
R ++ +Y C + G + +F + PP ++ PR + + + + L+C
Sbjct: 2356 --RVLRVRDAGLYTCLAESPAG-AIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLEC 2412
Query: 453 PFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAEN 512
P P + W ++G D L+++ + D G Y+C A N G
Sbjct: 2413 SVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSV 2472
Query: 513 QVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 572
R+E+ I P T L C+ P+ VSW KD PL + +
Sbjct: 2473 AFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPA--PLVSWRKDRVPLDPRSPRFE 2530
Query: 573 --EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDR 630
+ SL I V +D G Y C+AS D L VL P
Sbjct: 2531 ILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLE------------PPAIAPS 2578
Query: 631 PRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGV--WHDHSKYPGSVNSA 688
P +L LT + +P +A+ SP +P V W D K +
Sbjct: 2579 PSNLTLT-----AHTPALLPCEASGSP-------------KPLVVWWKDGQKLDFRLQQG 2620
Query: 689 VLRL-----------SPYVNYQFRVIAINEVGSSH 712
RL P + QF + NEVG +H
Sbjct: 2621 AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAH 2655
Score = 151 bits (382), Expect = 3e-36
Identities = 149/571 (26%), Positives = 230/571 (40%), Gaps = 37/571 (6%)
Query: 40 PPTI---TKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 96
PP I T++ ++ V+ + ++C A GNP P+ W +N F+ PR+ +
Sbjct: 1650 PPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFS--PSPRLQVLEDG 1707
Query: 97 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGA 156
L + Y C A N+ G+A L+V P +L+ V +
Sbjct: 1708 QVLQVSTAEVADA----ASYMCVAENQAGSA-EKLFTLRVQVPPRIAGLDLEQVTAILNS 1762
Query: 157 PLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNAR 216
++L C+ P+P + W S ++ L L D Y+C A
Sbjct: 1763 SVSLPCDVHAH-PNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGM-YTCEA- 1819
Query: 217 FHFTHTIQQKNPFTLKVLTTRGVAERTPSFMY-PQGTASSQMVLRGMDLLLECIASGVPT 275
+ + L VL P+F P+G + +V G +L C +P
Sbjct: 1820 --LNAAGRDQKLVQLSVLVP-------PAFRQAPRGPQDAVLVRVGDKAVLSCETDALPE 1870
Query: 276 PDIAWYKKGGDLP-SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVK 334
P + WYK G L + + + + L I D G Y C SN G T ++ V+
Sbjct: 1871 PTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ 1930
Query: 335 AAPYWLDEPKNLILA--PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT 392
P + + PK ++ G L C +G P PTV W+ + P++S+ + G
Sbjct: 1931 VPPTF-ENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRL 1989
Query: 393 IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDC 452
+ R Q + Y C N + V+VL P S + V+ RLDC
Sbjct: 1990 QLSR-LQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDC 2048
Query: 453 PFFGSPIPTLRWFKNGQGSNLDGGNY--HVYENGSLEIKMIRKEDQGIYTCVATNILGKA 510
G P P + W K+G D G + + GSL +K +R D G YTCVA N G+
Sbjct: 2049 EADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGED 2108
Query: 511 ENQVRLEVKDPTRIYRMPEDQ---VARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIG 567
+ V P I + + V+R G V + C V+ P + VSWLKD PL +
Sbjct: 2109 ARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIH--VSWLKDGLPLPLS 2166
Query: 568 NR--MKKEDDSLTIFGVAERDQGSYTCVAST 596
R + +L I V D G +TCVA++
Sbjct: 2167 QRTLLHGSGHTLRISKVQLADAGIFTCVAAS 2197
Score = 150 bits (378), Expect = 9e-36
Identities = 160/613 (26%), Positives = 236/613 (38%), Gaps = 50/613 (8%)
Query: 34 QNELTQPPTITKQSAKDHI-VDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSM 92
Q + +PP I + + P + + C+A+G P P+ W ++ + R+
Sbjct: 2296 QLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALT-----RLEN 2350
Query: 93 RRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTA-LSNRIRLQVSKSPLWPKENLDPVV 151
R+ T V+ R G Y C A + G S R+R+Q + + P+ V
Sbjct: 2351 NSRA-TRVLRVRDAGL-------YTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVG 2402
Query: 152 VQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDY 211
+ G L L+C+ P+P I W + + +D G + DY
Sbjct: 2403 LAPGQ-LVLECSVEAE-PAPKITWHRDGIV-LQEDAHTQFPERGRFLQLQALSTADSGDY 2459
Query: 212 SCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIAS 271
SC AR T F +++ T + P+ V LL C A
Sbjct: 2460 SCTARNAAGST---SVAFRVEIHTVPTIRSGPPAVN----------VSVNQTALLPCQAD 2506
Query: 272 GVPTPDIAWYKKGGDLPSDKAKFENFNK-ALRITNVSEEDSGEYFCLASNKMGSIRHTIS 330
GVP P ++W K L +FE + +LRI V +D+G Y CLASN GS R
Sbjct: 2507 GVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRD 2566
Query: 331 VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQ-SAPPNPNREVA 389
+RV P P NL L L C A+G+PKP V W +G+ L R +
Sbjct: 2567 LRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLP 2626
Query: 390 GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTR 449
+ ++ A ++C SNE G + + VPP + + V +
Sbjct: 2627 SNALLLTAPGPQDSAQFECVVSNEVGE-AHRLYQVTVHVPPTIADDQTD-FTVTMMAPVV 2684
Query: 450 LDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGK 509
L C G P PT+ W K G G Y V +G+LEI G YTC A N G
Sbjct: 2685 LTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGV 2744
Query: 510 AENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIG-N 568
A V L V+ + +P A V L C P + T++W K+ + G +
Sbjct: 2745 AHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIP--RPTITWQKEGLNVATGVS 2802
Query: 569 RMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV---------LADQATPTNR 619
L I + D G+Y C+A + K L V L D +T
Sbjct: 2803 TQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGS 2862
Query: 620 LAALP---KGRPD 629
A LP +G P+
Sbjct: 2863 HAFLPCKARGSPE 2875
Score = 149 bits (376), Expect = 2e-35
Identities = 146/591 (24%), Positives = 236/591 (39%), Gaps = 52/591 (8%)
Query: 40 PPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTL 99
PP IT + V + + C A G P+P+ W ++ + A P + + L
Sbjct: 785 PPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVL 844
Query: 100 VIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLD-PVVVQEGAPL 158
+ + R + G Y C A + G + + LQV P E L+ VV E L
Sbjct: 845 TL---ASARASD-SGRYSCVAVSAVGEDRQDVV-LQVHMPPSILGEELNVSVVANESVAL 899
Query: 159 TLQCNPPPGLPSPVIFWMSSS--MEP-----ITQDKRVSQGHNGDLYFSNVMLQDMQTDY 211
Q + +P PV+ W +EP ++ DK + Q D++ + Y
Sbjct: 900 ECQSH---AMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAG--------HY 948
Query: 212 SCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIAS 271
+C A + + + L V ++P + + V G L C
Sbjct: 949 TCEA---LNQAGRSEKHYNLNVWVAP---------VFPLRESHTLTVREGHPTSLSCECR 996
Query: 272 GVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEED---SGEYFCLASNKMGSIRHT 328
GVP P I+W K G LP + A ++ + R+ + + G Y C SN +G+
Sbjct: 997 GVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQD 1056
Query: 329 ISVRVKAAPYWL---DEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPN 385
+ + V P + P + + L C A G P PTV W +G+P+ A
Sbjct: 1057 LQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPV-GAELGLQ 1115
Query: 386 REVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQL--IRVI 443
+ G ++ Q + Y C N G +SVL VPP ++ + L I
Sbjct: 1116 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVL-VPPELIGDLDPLTNITAA 1174
Query: 444 LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 503
L++ L C G P P +RWF+ + + Y + L++ +++D G+Y+C+A
Sbjct: 1175 LHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLA 1234
Query: 504 TNILGKAENQVRLEVKDPTRIYRMPEDQVAR--RGTTVQLECRVKHDPSLKLTVSWLKDD 561
+N G+A +EV P I ++V + G T L C V P KLT W KD
Sbjct: 1235 SNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLT--WFKDG 1292
Query: 562 EPLYIGNRMKKEDDS--LTIFGVAERDQGSYTCVASTELDQDLAKAYLTVL 610
PL G+ D L + G Y+C+A+ + + L+VL
Sbjct: 1293 RPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVL 1343
Score = 143 bits (360), Expect = 1e-33
Identities = 145/562 (25%), Positives = 224/562 (39%), Gaps = 45/562 (8%)
Query: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
+ CE +G P P W ++ + + + G L+ G EG Y C
Sbjct: 991 LSCECRGVPFPKISWRKDGQPLP-GEGAGLQHVSAVGRLLY---LGQAQLAQEGTYTCEC 1046
Query: 121 RNKFGTALSNRIRLQVSKSP--LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSS 178
N G + S ++L+V P P+E V V + TL+CN G P P + W
Sbjct: 1047 SNVVGNS-SQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNAT-GKPPPTVTWERD 1104
Query: 179 SMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRG 238
+P+ + + + G YSC A + ++K F L VL
Sbjct: 1105 G-QPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAE-NLAGRAERK--FELSVLVP-- 1158
Query: 239 VAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL-PSDKAKFENF 297
P + ++ L L C A G+P P I W++ + P +
Sbjct: 1159 -----PELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAG 1213
Query: 298 NKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA--PGEDGR 355
L++T E+DSG Y CLASN+ G R SV V P +E ++ G+
Sbjct: 1214 GWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAH 1273
Query: 356 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQ--ISSRAVYQCNTSNE 413
L+C G+P+P + W +G PL + ++ D ++ + Q +SS Y C +N
Sbjct: 1274 LMCNVTGHPQPKLTWFKDGRPLARGDAH---HISPDGVLLQVLQANLSSAGHYSCIAANA 1330
Query: 414 HGYLLANAFVSVLDVPPRMLSPRNQL---IRVILYNRTRLDCPFFGSPIPTLRWFKNGQG 470
G + +SVL P + + + V + N L C P P + W K+G
Sbjct: 1331 VGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAP 1390
Query: 471 SNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPED 530
+ L+I +KED G YTCV TN LG+A +EV P I + +D
Sbjct: 1391 FEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISK--DD 1448
Query: 531 QVARRG---------TTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK--KEDDSLTI 579
+ G +T+ LEC P T+ W KD +P+ +R++ E L I
Sbjct: 1449 PLGEVGVKEVKTKVNSTLTLECESWAVP--PPTIRWYKDGQPVTPSSRLQVLGEGRLLQI 1506
Query: 580 FGVAERDQGSYTCVASTELDQD 601
D G Y CVA+ +D
Sbjct: 1507 QPTQVSDSGRYLCVATNVAGED 1528
Score = 141 bits (356), Expect = 3e-33
Identities = 156/628 (24%), Positives = 253/628 (40%), Gaps = 86/628 (13%)
Query: 33 IQNELTQPPTIT-KQSAKDHIVDPRDNIL-IECEAKGNPAPSFHWTRNSRFFNIAKDPRV 90
+Q E+ PP I + + +D + +EC A G P P+ W R+ + + + +
Sbjct: 1057 LQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQ--PVGAELGL 1114
Query: 91 SMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKE---NL 147
++ + +L ++ + G Y C A N L+ R + S L P E +L
Sbjct: 1115 QLQNQGQSLHVERAQAA----HTGRYSCVAEN-----LAGRAERKFELSVLVPPELIGDL 1165
Query: 148 DPVVVQEGA---PLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVML 204
DP+ A PLTL C G+P P I W EP VS G + L ML
Sbjct: 1166 DPLTNITAALHSPLTLLCEAM-GIPPPAIRWFRGE-EP------VSPGEDTYLLAGGWML 1217
Query: 205 QDMQTD------YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMV 258
+ QT YSC A + + F+++VL P + + V
Sbjct: 1218 KMTQTQEQDSGLYSCLAS---NEAGEARRNFSVEVLV--------PPSIENEDLEEVIKV 1266
Query: 259 LRGMDLLLECIASGVPTPDIAWYKKGGDLP-SDKAKFENFNKALRITNVSEEDSGEYFCL 317
L G L C +G P P + W+K G L D L++ + +G Y C+
Sbjct: 1267 LDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCI 1326
Query: 318 ASNKMGSIRHTISVRVKAAPYWL-----DEPKNLILAPGEDGRLVCRANGNPKPTVQWMV 372
A+N +G + V AP L + + + L+C A P P + WM
Sbjct: 1327 AANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMK 1386
Query: 373 NGEPLQSAPPNPNREVAGDT--IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPP 430
+G P +++ N ++ T + + Q Y C +NE G + N V VL +PP
Sbjct: 1387 DGAPFEASR---NIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVL-IPP 1442
Query: 431 RMLS--PRNQL----IRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENG 484
+ P ++ ++ + + L+C + P PT+RW+K+GQ + E
Sbjct: 1443 SISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGR 1502
Query: 485 SLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYR----------MPEDQVAR 534
L+I+ + D G Y CVATN+ G+ + + ++ P + + ++ AR
Sbjct: 1503 LLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEAR 1562
Query: 535 RGTT----------VQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK--KEDDSLTIFGV 582
G T L C P LT W ++D+PL G+ + + L I V
Sbjct: 1563 GGVTEYREIVENNPAYLYCDTNAIPPPDLT--WYREDQPLSAGDEVSVLQGGRVLQIPLV 1620
Query: 583 AERDQGSYTCVASTELDQDLAKAYLTVL 610
+ G Y+C AS E+ +D L VL
Sbjct: 1621 RAENAGRYSCKASNEVGEDWLHYELLVL 1648
Score = 134 bits (336), Expect = 7e-31
Identities = 153/607 (25%), Positives = 231/607 (38%), Gaps = 88/607 (14%)
Query: 25 IEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNI 84
+++P + L Q TI Q + + C+A G+P P+ W +N R
Sbjct: 493 VQVPPQLLVAEGLGQVTTIVGQPLE-----------LPCQASGSPVPTIQWLQNGR--PA 539
Query: 85 AKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPK 144
+ V + + TL ID ++ G + C A N+ GTA + ++VS W
Sbjct: 540 EELAGVQVASQGTTLHIDHVE----LDHSGLFACQATNEAGTAGAE---VEVSVHGEWAP 592
Query: 145 ENLDPVVVQ------EGAPLTLQCNPP--------------PGLPSPVIFWMSSSMEPIT 184
L+ + Q + C+PP G SP W + P
Sbjct: 593 GVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIP-- 650
Query: 185 QDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTP 244
V+ L V L+D + Y+C A + K LKVL +
Sbjct: 651 ----VAYSLPPPLQIEKVDLRD-EGIYTCAAT---NLAGESKREVALKVLVPPNI----- 697
Query: 245 SFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFN-KALRI 303
+ ++ VL + LEC+ASGVP PD++W+K + S + + + LRI
Sbjct: 698 -----EPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRI 752
Query: 304 TNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDG--------R 355
D+G Y C+ASN GS +RV P + L P G R
Sbjct: 753 EQAQLSDAGSYRCVASNVAGSTELRYGLRVNV-------PPRITLPPSLPGPVLVNTPVR 805
Query: 356 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTIIFRDTQISSRAVYQCNTSNE 413
L C A G P PT+ W+ +G P+ A P +V G + + S Y C +
Sbjct: 806 LTCNATGAPSPTLMWLKDGNPVSPA-GTPGLQVFPGGRVLTLASARASDSGRYSCVAVSA 864
Query: 414 HGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNL 473
G + + V +PP +L + V+ L+C P P L W+K+G+
Sbjct: 865 VGEDRQDVVLQV-HMPPSILGEELN-VSVVANESVALECQSHAMPPPVLSWWKDGRPLEP 922
Query: 474 DGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV-KDPTRIYRMPEDQV 532
G + + L++ D G YTC A N G++E L V P R
Sbjct: 923 RPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLT 982
Query: 533 ARRGTTVQLECRVKHDPSLKLTVSWLKDDEPL---YIGNRMKKEDDSLTIFGVAE-RDQG 588
R G L C + P K +SW KD +PL G + L G A+ +G
Sbjct: 983 VREGHPTSLSCECRGVPFPK--ISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEG 1040
Query: 589 SYTCVAS 595
+YTC S
Sbjct: 1041 TYTCECS 1047
Score = 129 bits (324), Expect = 2e-29
Identities = 127/508 (25%), Positives = 200/508 (39%), Gaps = 44/508 (8%)
Query: 40 PPTITKQSAKDHIVDPR-DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPR-----VSMR 93
PP+I + K ++ ++ +EC+A G P P W ++++ + +
Sbjct: 94 PPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWG 153
Query: 94 RRSGTLVIDF------------RSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPL 141
+ G ++D RSG R + G Q A G A + + SP
Sbjct: 154 QVGGHRLLDEGQSLHFPRIQPGRSGRRGAQAGGSAQTKAPWXAGLAGFEQFPTPHAFSPP 213
Query: 142 WPKENLDPVVVQE-----GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGD 196
P L QE GA + LQC G+P+P + W + + +G
Sbjct: 214 APPSVLGAGAAQEVLGLAGADVELQCWTS-GVPTPQVEWTKDRQPVLPGGPHLQVQEDGQ 272
Query: 197 LYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQ 256
+ + Y C A F+ QQ F L+V P ++
Sbjct: 273 VLRITGSHVGDEGRYQCVA---FSPAGQQARDFQLRV--------HAPPTIWGSNETGEV 321
Query: 257 MVLRGMDLLLECIASGVPTPDIAWYKKGGDLP-SDKAKFENFNKALRITNVSEEDSGEYF 315
V+ + L C A GVPTP+I W+K G LP S K + + L++ D+G Y
Sbjct: 322 AVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYT 381
Query: 316 CLASNKMGSIRHTISVRVKAAPYWLD---EPKNLILAPGEDGRLVCRANGNPKPTVQWMV 372
C ASN +G+ + V P P + G L C A G+P PT+ W
Sbjct: 382 CKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHH 441
Query: 373 NGEPLQSAPPNPNR-EVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPR 431
G P+ A N +R E G + +S +Y C S+ G + V V VPP+
Sbjct: 442 EGLPV--AESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEV-QVPPQ 498
Query: 432 MLSPRNQ-LIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKM 490
+L + I+ L C GSP+PT++W +NG+ + G + +L I
Sbjct: 499 LLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDH 558
Query: 491 IRKEDQGIYTCVATNILGKAENQVRLEV 518
+ + G++ C ATN G A +V + V
Sbjct: 559 VELDHSGLFACQATNEAGTAGAEVEVSV 586
Score = 119 bits (297), Expect = 2e-26
Identities = 146/584 (25%), Positives = 231/584 (39%), Gaps = 48/584 (8%)
Query: 63 CEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARN 122
C G P P W + + P V++ G+L F + P + G+Y+C A N
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEE-GSL---FLASVSPAD-SGDYECQATN 78
Query: 123 KFGTALSNRIRLQVSKSPLWPKENLDPVVV-QEGAPLTLQCNPPPGLPSPVIFWMSSSME 181
+ G+ S R +L V P ++ V G LTL+C+ G P P I W+ +
Sbjct: 79 EVGST-SRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDAN-GFPVPEIVWLKDAQ- 135
Query: 182 PITQDKRVSQGHNGDLYFSNV----MLQD--------MQTDYSCNARFHFTHTIQQKNPF 229
+ G+ DL + V +L + +Q S + Q K P+
Sbjct: 136 -LVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQPGRSGRRGAQAGGSAQTKAPW 194
Query: 230 TLKVL------TTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYK- 282
+ T + P + G A + L G D+ L+C SGVPTP + W K
Sbjct: 195 XAGLAGFEQFPTPHAFSPPAPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKD 254
Query: 283 KGGDLPSDK-AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLD 341
+ LP + + + LRIT D G Y C+A + G +RV A P
Sbjct: 255 RQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWG 314
Query: 342 EPKNLILAPGEDG--RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV---AGDTIIFR 396
+ +A ED +L+C A G P P + W +G L P + V G +
Sbjct: 315 SNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALL----PTSTKVVYTRGGRQLQLG 370
Query: 397 DTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRM--LSPRNQLIRVILYNRTRLDCPF 454
Q S VY C SN G + V VPP + R +++ + L+C
Sbjct: 371 RAQSSDAGVYTCKASNAVGAAEKATRLDVY-VPPTIEGAGGRPYVVKAVAGRPVALECVA 429
Query: 455 FGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQV 514
G P PTL W G + + L ++ + G+Y+CVA++ G+A Q
Sbjct: 430 RGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQY 489
Query: 515 RLEVKDPTRIYRMPE-DQVAR-RGTTVQLECRVKHDPSLKLTVSWLKDDEPL--YIGNRM 570
+EV+ P ++ QV G ++L C+ P T+ WL++ P G ++
Sbjct: 490 SVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSP--VPTIQWLQNGRPAEELAGVQV 547
Query: 571 KKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQA 614
+ +L I V G + C A+ E A+ ++V + A
Sbjct: 548 ASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWA 591
Score = 119 bits (297), Expect = 2e-26
Identities = 102/396 (25%), Positives = 173/396 (43%), Gaps = 32/396 (8%)
Query: 37 LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 96
+ Q P + + D + + C+A+G+P P+ W ++ + + A+ + S
Sbjct: 2842 VVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTI--QPS 2899
Query: 97 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGA 156
G L++ G + G Y C A N G A R+ L + P++ D + + G
Sbjct: 2900 GELLVKNLEG----QDAGTYTCTAENAVGRA-RRRVHLTILVLPVFTTLPGDRSL-RLGD 2953
Query: 157 PLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNA- 215
L L+C G P+P I W + P+T+ VS+ G + ++ Y C A
Sbjct: 2954 RLWLRC-AARGSPTPRIGWTVND-RPVTEG--VSEQDGGSTLQRAAVSREDSGTYVCWAE 3009
Query: 216 -RFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLR-GMDLLLECIASGV 273
R T + + VL QG A S +V G + L+C+ G
Sbjct: 3010 NRVGRTQAVSFVHVKEAPVL---------------QGEAFSYLVEPVGGSIQLDCVVRGD 3054
Query: 274 PTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRV 333
P PDI W K G L + + N +L I +D+G Y CLA N+MG + + + +
Sbjct: 3055 PVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVL 3114
Query: 334 KAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTI 393
++AP + EP+++ + G+D L C+A G P PT++W+ G+PL+++ R + ++
Sbjct: 3115 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRAS--RRLRTLPDGSL 3172
Query: 394 IFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVP 429
+ + Y C N G A AF+ V P
Sbjct: 3173 WLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEP 3208
Score = 116 bits (291), Expect = 1e-25
Identities = 151/596 (25%), Positives = 229/596 (38%), Gaps = 54/596 (9%)
Query: 40 PPTITKQSAKDHIVDPRDNIL-IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGT 98
PPTI + + D+++ + CEA+G P P+ W ++ + +V R
Sbjct: 309 PPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGAL--LPTSTKVVYTRGGRQ 366
Query: 99 LVIDFRSGGRPEEYE-GEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQ--EG 155
L + GR + + G Y C A N G A RL V P P VV+ G
Sbjct: 367 LQL-----GRAQSSDAGVYTCKASNAVGAA-EKATRLDVYVPPTIEGAGGRPYVVKAVAG 420
Query: 156 APLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNA 215
P+ L+C G PSP + W + P+ + +G + + YSC A
Sbjct: 421 RPVALEC-VARGHPSPTLSWHHEGL-PVAESNESRLETDGSVLRLESPGEASSGLYSCVA 478
Query: 216 RFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPT 275
+P VL + P + +G ++ G L L C ASG P
Sbjct: 479 ----------SSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIV-GQPLELPCQASGSPV 527
Query: 276 PDIAWYKKGGDLPSDK---AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVR 332
P I W + G P+++ + + L I +V + SG + C A+N+ G+ + V
Sbjct: 528 PTIQWLQNG--RPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVS 585
Query: 333 VKA--APYWLDEP--------KNLILAPGEDGRLVCRANG-NPKPTV--QWMVNGEPLQS 379
V AP L+ P ++ P V R G +PKP + W G
Sbjct: 586 VHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGE 645
Query: 380 APPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQL 439
P + + +Y C +N G + VL VPP + +
Sbjct: 646 PTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVL-VPPNI--EPGPV 702
Query: 440 IRVILYNRT-RLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI 498
+ +L N + L+C G P P + WFK Q + G + L I+ + D G
Sbjct: 703 NKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGS 762
Query: 499 YTCVATNILGKAENQVRLEVKDPTRIYRMPE-DQVARRGTTVQLECRVKHDPSLKLTVSW 557
Y CVA+N+ G E + L V P RI P T V+L C PS T+ W
Sbjct: 763 YRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPS--PTLMW 820
Query: 558 LKDDEPL----YIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
LKD P+ G ++ LT+ D G Y+CVA + + +D L V
Sbjct: 821 LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 876
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 180 bits (457), Expect = 7e-45
Identities = 164/596 (27%), Positives = 247/596 (41%), Gaps = 46/596 (7%)
Query: 40 PPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTR-NSRFFNIAKDPRVSMRRRSGT 98
PPTI D V +++ C + G PAP+ W++ ++ RVS SG
Sbjct: 3856 PPTIADDQT-DFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSP---SGA 3911
Query: 99 LVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLW-PKENLDPVVVQEGAP 157
L I G + G Y C ARN G A + L V SP+ P ++ V +E
Sbjct: 3912 LEI----GQALPIHAGRYTCSARNSAGVA-HKHVFLTVQASPVVKPLPSVVRAVAEEEVL 3966
Query: 158 LTLQCNPPPGLPSPVIFWMSSSMEPITQ-DKRVSQGHNGDLYFSNVMLQDMQTDYSCNAR 216
L + + G+P P I W + T +V G G L ++ +D +Y C A
Sbjct: 3967 LPCEAS---GIPRPTITWQKEGLNVATGVSTQVLPG--GQLRIAHASPEDAG-NYLCIA- 4019
Query: 217 FHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTP 276
KN + TR V + P + G L C A G P P
Sbjct: 4020 ---------KNSAGSAMGKTRLVVQVPPVI---ENGLPDLSTTEGSHAFLPCKARGSPEP 4067
Query: 277 DIAWYKKGGDLPSDKAKFE-NFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA 335
+I W K G + + KF + L + N+ +D+G Y C A N +G R + + +
Sbjct: 4068 NITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILV 4127
Query: 336 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIF 395
P + P + L G+ L C A G+P P + W VN P+ + + G T+
Sbjct: 4128 LPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGV---SEQDGGSTLQR 4184
Query: 396 RDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFF 455
Y C N G A +FV V + P + L+ + +LDC
Sbjct: 4185 AAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPV-GGSIQLDCVVR 4243
Query: 456 GSPIPTLRWFKNG---QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAEN 512
G P+P + W K+G +GS+L H +NGSL I ++D G Y C+A N +G A+
Sbjct: 4244 GDPVPDIHWIKDGLPLRGSHLR----HQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKK 4299
Query: 513 QVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 572
V L ++ P+D R G V L C+ +P+ T+ WL+ +PL R++
Sbjct: 4300 VVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPT--PTIEWLQAGQPLRASRRLRT 4357
Query: 573 -EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGR 627
D SL + V D G+Y CVA L A+A+L V + + + GR
Sbjct: 4358 LPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSWGSMTGVINGR 4413
Score = 161 bits (407), Expect = 4e-39
Identities = 152/569 (26%), Positives = 241/569 (42%), Gaps = 49/569 (8%)
Query: 40 PPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTL 99
PP + A + V P + ++ C G + W R+ R A RV+ + L
Sbjct: 517 PPQLVP--APNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLP-ASTGRVA---QLADL 570
Query: 100 VIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLT 159
++ SG P + G YQC A N G ++ + L V ++P + +G +
Sbjct: 571 SLEI-SGIIPTD-GGRYQCVASNANGVTRAS-VWLLVREAPQ-VSIHTSSQHFSQGVEVK 626
Query: 160 LQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHF 219
+ C+ G P+P I W S + + +D R+ G L V +D +YSC A
Sbjct: 627 VSCSAS-GYPTPHISWSRES-QALQEDSRIHVDAQGTLIIQGVAPEDAG-NYSCQA---- 679
Query: 220 THTIQQKNPFTLKVLTTRGVAERTPSFMY---PQGTASSQMVLR--GMDLLLECIASGVP 274
T+ + G + T + Y P +A + +VL G + +L C ASGVP
Sbjct: 680 TNEV--------------GTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVP 725
Query: 275 TPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVK 334
P + WY+ G L A + + LRI E D+G Y C A N++G I + V
Sbjct: 726 PPRVIWYR--GGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVG 783
Query: 335 AAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMV-NGEPLQ----SAPPNPNREVA 389
AP + P+++ + G L CRA G P PTV W +G+PL + + +R+
Sbjct: 784 HAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPD 843
Query: 390 GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTR 449
+ F +A Y C N G + A A + V P ++ +RV+
Sbjct: 844 SGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVS 903
Query: 450 LDCPFF-GSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILG 508
L C G P+P W K+G+ G + + +GSL + +E G Y+CVATN G
Sbjct: 904 LPCIVLAGRPLPERHWLKDGRPLP-PGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAG 962
Query: 509 KAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYI-- 566
V L V+ P RI+ + G L C P+ T++W K+ L
Sbjct: 963 SQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPA--PTITWTKETNALTSRG 1020
Query: 567 GNRMKKEDDSLTIFGVAERDQGSYTCVAS 595
+ ++ +L I + +D G+Y C A+
Sbjct: 1021 PHYNVSKEGTLLIAQPSAQDAGAYVCTAT 1049
Score = 157 bits (397), Expect = 6e-38
Identities = 156/612 (25%), Positives = 255/612 (41%), Gaps = 58/612 (9%)
Query: 41 PTI---TKQSAKDHIVDPRDN-ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 96
PTI + SA + + +N I + CEA P+P+ W ++ F +++ ++ +
Sbjct: 2537 PTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQL-LPGTH 2595
Query: 97 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR-----IRLQVSKSPLWPKENLDPVV 151
G +++ + +E G+Y C N+ G A+ N I +SK + + V
Sbjct: 2596 GLQILNAQ-----KEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVK 2650
Query: 152 VQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDY 211
+ + LTL+C +P P I W +P+T R+ G L LQ T
Sbjct: 2651 TKVNSTLTLECESW-AVPPPTIRWYKDG-QPVTPSSRLQVLGEGRL------LQIQPTQV 2702
Query: 212 SCNARFHFTHT------------IQQKNPFTLKVLTTRGVAERTPSFMYPQGTASS-QMV 258
S + R+ T + Q P KV E +G + + +
Sbjct: 2703 SDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREI 2762
Query: 259 LRGMDLLLECIASGVPTPDIAWYKKGGDLPS-DKAKFENFNKALRITNVSEEDSGEYFCL 317
+ L C + +P PD+ WY++ L + D+ + L+I V E++G Y C
Sbjct: 2763 VENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCK 2822
Query: 318 ASNKMGSIRHTISVRVKAAPYWLDEPKNLI----LAPGEDGRLVCRANGNPKPTVQWMVN 373
ASN++G + V P L + + L+ + L C A GNP PT+ W+ N
Sbjct: 2823 ASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQN 2882
Query: 374 GEPLQSAPPNPNREVAGDTIIFR--DTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPR 431
G P P+P +V D + + +++ A Y C N+ G F + VPPR
Sbjct: 2883 GLPFS---PSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA-EKLFTLRVQVPPR 2938
Query: 432 MLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMI 491
+ + + IL + L C P P + W+K+ Q +L + + +L++
Sbjct: 2939 IAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRA 2998
Query: 492 RKEDQGIYTCVATNILGKAENQVRLEVKDP---TRIYRMPEDQV-ARRGTTVQLECRVKH 547
R D G+YTC A N G+ + V+L V P + R P+D V R G L C
Sbjct: 2999 RLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCET-- 3056
Query: 548 DPSLKLTVSWLKDDEPLYIGNRMK--KEDDSLTIFGVAERDQGSYTCVASTELDQDLAKA 605
D + TV+W KD +PL + R + + L I D+G Y+C S + +
Sbjct: 3057 DALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTF 3116
Query: 606 YLTVLADQATPT 617
LTV Q PT
Sbjct: 3117 TLTV---QVPPT 3125
Score = 156 bits (394), Expect = 1e-37
Identities = 152/563 (26%), Positives = 234/563 (41%), Gaps = 70/563 (12%)
Query: 57 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYE--- 113
D ++ CE P P+ W ++ + P V +R R G R E E
Sbjct: 3048 DKAVLSCETDALPEPTVTWYKDGQ-------PLVLAQRTQA-----LRGGQRLEIQEAQV 3095
Query: 114 ---GEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPS 170
G Y C N G A+ L V P + + V G+PL L C+ G+P+
Sbjct: 3096 SDKGLYSCKVSNVAGEAVRT-FTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVS-GVPA 3153
Query: 171 PVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFT 230
P + W+ M + G L S + T Y+C A + + F
Sbjct: 3154 PTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGT-YTCVAE---NTQAEARKDFV 3209
Query: 231 LKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD 290
+ VL VA R S G A VL G ++ L+C A G P PD+AW K G L D
Sbjct: 3210 VAVL----VAPRIRS----SGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQD 3261
Query: 291 KAKFENF---NKALRITNVSEEDSGEYFCLASNKMG--SIRHTISVRV-KAAPYWLDEPK 344
F +L + + D+G Y C+A N G + HT++V V D
Sbjct: 3262 MGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSG 3321
Query: 345 NLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV---AGDTIIFRDTQIS 401
L+ PGE +VC G+P V W+ +G PL P R + +G T+ Q++
Sbjct: 3322 TLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPL----PLSQRTLLHGSGHTLRISKVQLA 3377
Query: 402 SRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSP---RNQLIRVILYNRTRLDCPFFGSP 458
++ C ++ G N F + VPP +L P +N ++ V+ + L C G P
Sbjct: 3378 DAGIFTCVAASPAGVADRN-FTLQVQVPP-VLEPVEFQNDVV-VVRGSLVELPCEARGVP 3434
Query: 459 IPTLRWFKNGQ---GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR 515
+P + W K+G+ +L+ G SL+++ + D G Y+CVA + G+A +
Sbjct: 3435 LPLVSWMKDGEPLLSQSLEQG-------PSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQ 3487
Query: 516 LEVKDPTRI--YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKE 573
L V +P I P + G ++L C + P +T W KD + L + E
Sbjct: 3488 LTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNIT--WHKDGQAL-----TRLE 3540
Query: 574 DDSLTIFGVAERDQGSYTCVAST 596
++S + RD G YTC+A +
Sbjct: 3541 NNSRATRVLRVRDAGLYTCLAES 3563
Score = 154 bits (389), Expect = 5e-37
Identities = 168/695 (24%), Positives = 262/695 (37%), Gaps = 80/695 (11%)
Query: 37 LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 96
L P + A++H V + ++CEA G P P W ++ P +
Sbjct: 3213 LVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDG 3272
Query: 97 GTLVIDFRSGGRPEEYEGEYQCFARNKFG-TALSNRIRLQVSKSPLWPKENLDPVVVQEG 155
G+LV+ G G Y C A N G A + + + V + + +V + G
Sbjct: 3273 GSLVLK----GLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPG 3328
Query: 156 APLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNA 215
+T+ C P G P + W+ + + + G L S V L D ++C A
Sbjct: 3329 ELVTMVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGI-FTCVA 3386
Query: 216 RFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPT 275
+ +N FTL+V + P + P + +V+RG + L C A GVP
Sbjct: 3387 A--SPAGVADRN-FTLQV--------QVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPL 3435
Query: 276 PDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA 335
P ++W K G L S + +L++ V DSG Y C+A ++ G R + V
Sbjct: 3436 PLVSWMKDGEPLLSQSLE---QGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVME 3492
Query: 336 APYWLD--EPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTI 393
P+ D +P L L PG L+C A G P+P + W +G+ L N
Sbjct: 3493 PPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRAT------ 3546
Query: 394 IFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNRTRLDC 452
R ++ +Y C + G + +F + PP ++ PR + + + + L+C
Sbjct: 3547 --RVLRVRDAGLYTCLAESPAG-AIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLEC 3603
Query: 453 PFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAEN 512
P P + W ++G D L+++ + D G Y+C A N G
Sbjct: 3604 SVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSV 3663
Query: 513 QVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 572
R+E+ I P T L C+ P+ VSW KD PL + +
Sbjct: 3664 AFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPA--PLVSWRKDRVPLDPRSPRFE 3721
Query: 573 --EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDR 630
+ SL I V +D G Y C+AS D L VL P
Sbjct: 3722 ILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLE------------PPAIAPS 3769
Query: 631 PRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGV--WHDHSKYPGSVNSA 688
P +L LT + +P +A+ SP +P V W D K +
Sbjct: 3770 PSNLTLT-----AHTPALLPCEASGSP-------------KPLVVWWKDGQKLDFRLQQG 3811
Query: 689 VLRL-----------SPYVNYQFRVIAINEVGSSH 712
RL P + QF + NEVG +H
Sbjct: 3812 AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAH 3846
Score = 152 bits (385), Expect = 1e-36
Identities = 144/563 (25%), Positives = 229/563 (40%), Gaps = 57/563 (10%)
Query: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
+ C A+GNP P W+++ V ++ R + F + + G Y+C A
Sbjct: 1139 LNCVAEGNPEPQLSWSKDG----------VVLQGRGPQGSVHFAAIRTSDA--GRYRCEA 1186
Query: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQ-EGAPLTLQCNPPPGLPSPVIFWMSS- 178
N G + + L+V + P W + ++ + G +L C P G P P + W
Sbjct: 1187 SNSAGVD-AWEVELRVLEPPHWGADETSGLLERVAGENASLPC-PARGTPKPQVTWRKGP 1244
Query: 179 SMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRG 238
S EP+ V+ G L+ ++V D DY C A T ++
Sbjct: 1245 SSEPLHGQPGVAVLEEGSLFLASVSPAD-SGDYECQATNEVGSTSRRAK----------- 1292
Query: 239 VAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK-------------GG 285
+ P + G ++ + G L LEC A+G P P+I W K G
Sbjct: 1293 LVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGW 1352
Query: 286 DLPSDKA---KFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDE 342
DL + + + ++L + E DSG Y C A N+ G+ + + V P L
Sbjct: 1353 DLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGA 1412
Query: 343 --PKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQI 400
+ ++ G D L C +G P P V+W + +P+ P+ + G + + +
Sbjct: 1413 GAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHV 1472
Query: 401 SSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIP 460
YQC + G + + V P S + V+ + +L C G P P
Sbjct: 1473 GDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTP 1532
Query: 461 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKE--DQGIYTCVATNILGKAENQVRLEV 518
+ WFK+G + L VY G ++++ R + D G+YTC A+N +G AE RL+V
Sbjct: 1533 NITWFKDG--ALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDV 1590
Query: 519 KDPTRIY---RMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDD 575
P I P A G V LEC + PS T+SW + P+ N + E D
Sbjct: 1591 YVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPS--PTLSWHHEGLPVAESNESRLETD 1648
Query: 576 S--LTIFGVAERDQGSYTCVAST 596
L + E G Y+CVAS+
Sbjct: 1649 GSVLRLESPGEASSGLYSCVASS 1671
Score = 151 bits (382), Expect = 3e-36
Identities = 149/571 (26%), Positives = 230/571 (40%), Gaps = 37/571 (6%)
Query: 40 PPTI---TKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 96
PP I T++ ++ V+ + ++C A GNP P+ W +N F+ PR+ +
Sbjct: 2841 PPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFS--PSPRLQVLEDG 2898
Query: 97 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGA 156
L + Y C A N+ G+A L+V P +L+ V +
Sbjct: 2899 QVLQVSTAEVADA----ASYMCVAENQAGSA-EKLFTLRVQVPPRIAGLDLEQVTAILNS 2953
Query: 157 PLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNAR 216
++L C+ P+P + W S ++ L L D Y+C A
Sbjct: 2954 SVSLPCDVHAH-PNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGM-YTCEA- 3010
Query: 217 FHFTHTIQQKNPFTLKVLTTRGVAERTPSFMY-PQGTASSQMVLRGMDLLLECIASGVPT 275
+ + L VL P+F P+G + +V G +L C +P
Sbjct: 3011 --LNAAGRDQKLVQLSVLVP-------PAFRQAPRGPQDAVLVRVGDKAVLSCETDALPE 3061
Query: 276 PDIAWYKKGGDLP-SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVK 334
P + WYK G L + + + + L I D G Y C SN G T ++ V+
Sbjct: 3062 PTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ 3121
Query: 335 AAPYWLDEPKNLILA--PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT 392
P + + PK ++ G L C +G P PTV W+ + P++S+ + G
Sbjct: 3122 VPPTF-ENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRL 3180
Query: 393 IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDC 452
+ R Q + Y C N + V+VL P S + V+ RLDC
Sbjct: 3181 QLSR-LQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDC 3239
Query: 453 PFFGSPIPTLRWFKNGQGSNLDGGNY--HVYENGSLEIKMIRKEDQGIYTCVATNILGKA 510
G P P + W K+G D G + + GSL +K +R D G YTCVA N G+
Sbjct: 3240 EADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGED 3299
Query: 511 ENQVRLEVKDPTRIYRMPEDQ---VARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIG 567
+ V P I + + V+R G V + C V+ P + VSWLKD PL +
Sbjct: 3300 ARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIH--VSWLKDGLPLPLS 3357
Query: 568 NR--MKKEDDSLTIFGVAERDQGSYTCVAST 596
R + +L I V D G +TCVA++
Sbjct: 3358 QRTLLHGSGHTLRISKVQLADAGIFTCVAAS 3388
Score = 150 bits (379), Expect = 7e-36
Identities = 148/591 (25%), Positives = 237/591 (40%), Gaps = 52/591 (8%)
Query: 40 PPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTL 99
PP IT + V + + C A G P+P+ W ++ + A P + + L
Sbjct: 1976 PPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVL 2035
Query: 100 VIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLD-PVVVQEGAPL 158
+ + R + G Y C A + G + + LQV P E L+ VV E L
Sbjct: 2036 TL---ASARASD-SGRYSCVAVSAVGEDRQDVV-LQVHMPPSILGEELNVSVVANESVAL 2090
Query: 159 TLQCNPPPGLPSPVIFWMSSS--MEP-----ITQDKRVSQGHNGDLYFSNVMLQDMQTDY 211
Q + +P PV+ W +EP ++ DK + Q D++ + Y
Sbjct: 2091 ECQSH---AMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAG--------HY 2139
Query: 212 SCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIAS 271
+C A H+ + N L V ++P + + V G L C
Sbjct: 2140 TCEALNQAGHSEKHYN---LNVWVAP---------VFPLRESHTLTVREGHPTSLSCECR 2187
Query: 272 GVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEED---SGEYFCLASNKMGSIRHT 328
GVP P I+W K G LP + A ++ + R+ + + G Y C SN +G+
Sbjct: 2188 GVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQD 2247
Query: 329 ISVRVKAAPYWL---DEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPN 385
+ + V P + P + + L C A G P PTV W +G+P+ A
Sbjct: 2248 LQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPV-GAELGLQ 2306
Query: 386 REVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQL--IRVI 443
+ G ++ Q + Y C N G +SVL VPP ++ + L I
Sbjct: 2307 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVL-VPPELIGDLDPLTNITAA 2365
Query: 444 LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 503
L++ L C G P P +RWF+ + + Y + L++ +++D G+Y+C+A
Sbjct: 2366 LHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLA 2425
Query: 504 TNILGKAENQVRLEVKDPTRIYRMPEDQVAR--RGTTVQLECRVKHDPSLKLTVSWLKDD 561
+N G+A +EV P I ++V + G T L C V P KLT W KD
Sbjct: 2426 SNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLT--WFKDG 2483
Query: 562 EPLYIGNRMKKEDDS--LTIFGVAERDQGSYTCVASTELDQDLAKAYLTVL 610
PL G+ D L + G Y+C+A+ + + L+VL
Sbjct: 2484 RPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVL 2534
Score = 150 bits (378), Expect = 9e-36
Identities = 160/613 (26%), Positives = 236/613 (38%), Gaps = 50/613 (8%)
Query: 34 QNELTQPPTITKQSAKDHI-VDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSM 92
Q + +PP I + + P + + C+A+G P P+ W ++ + R+
Sbjct: 3487 QLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALT-----RLEN 3541
Query: 93 RRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTA-LSNRIRLQVSKSPLWPKENLDPVV 151
R+ T V+ R G Y C A + G S R+R+Q + + P+ V
Sbjct: 3542 NSRA-TRVLRVRDAGL-------YTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVG 3593
Query: 152 VQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDY 211
+ G L L+C+ P+P I W + + +D G + DY
Sbjct: 3594 LAPGQ-LVLECSVEAE-PAPKITWHRDGIV-LQEDAHTQFPERGRFLQLQALSTADSGDY 3650
Query: 212 SCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIAS 271
SC AR T F +++ T + P+ V LL C A
Sbjct: 3651 SCTARNAAGST---SVAFRVEIHTVPTIRSGPPAVN----------VSVNQTALLPCQAD 3697
Query: 272 GVPTPDIAWYKKGGDLPSDKAKFENFNK-ALRITNVSEEDSGEYFCLASNKMGSIRHTIS 330
GVP P ++W K L +FE + +LRI V +D+G Y CLASN GS R
Sbjct: 3698 GVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRD 3757
Query: 331 VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQ-SAPPNPNREVA 389
+RV P P NL L L C A+G+PKP V W +G+ L R +
Sbjct: 3758 LRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLP 3817
Query: 390 GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTR 449
+ ++ A ++C SNE G + + VPP + + V +
Sbjct: 3818 SNALLLTAPGPQDSAQFECVVSNEVGE-AHRLYQVTVHVPPTIADDQTD-FTVTMMAPVV 3875
Query: 450 LDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGK 509
L C G P PT+ W K G G Y V +G+LEI G YTC A N G
Sbjct: 3876 LTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGV 3935
Query: 510 AENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIG-N 568
A V L V+ + +P A V L C P + T++W K+ + G +
Sbjct: 3936 AHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIP--RPTITWQKEGLNVATGVS 3993
Query: 569 RMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV---------LADQATPTNR 619
L I + D G+Y C+A + K L V L D +T
Sbjct: 3994 TQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGS 4053
Query: 620 LAALP---KGRPD 629
A LP +G P+
Sbjct: 4054 HAFLPCKARGSPE 4066
Score = 144 bits (364), Expect = 4e-34
Identities = 171/692 (24%), Positives = 260/692 (37%), Gaps = 120/692 (17%)
Query: 38 TQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSG 97
T PP+++ +A + + +L+ CEA G P P W R +A + S +
Sbjct: 695 TDPPSVSAVNAVVLVAVGEEAVLV-CEASGVPPPRVIWYRGGLEMILAPEGSSSGK---- 749
Query: 98 TLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAP 157
R E G Y C A N+ G A S I+L V +P + D V V+ G
Sbjct: 750 -----LRIPAAQERDAGTYTCRAVNELGDA-SAEIQLAVGHAPQLTELPRD-VTVELGRS 802
Query: 158 LTLQCNPPPGLPSPVIFWMSSSMEPIT------QDKRVSQGHNGDLYFSNVMLQDMQTDY 211
L C G P P + W +P+ + R Q +G L+F +V +D Q Y
Sbjct: 803 ALLACRAT-GRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPED-QAPY 860
Query: 212 SCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIA- 270
C AR F K +++ T + S +A + VL G + L CI
Sbjct: 861 VCEARNVFG-----KVQAEARLIVTGHAPPQIAS------SAPTVRVLEGQPVSLPCIVL 909
Query: 271 SGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTIS 330
+G P P+ W K G LP + +L + +E +G Y C+A+N GS +
Sbjct: 910 AGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVE 969
Query: 331 VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG 390
+ V+ P + I G L C A+G P PT+ W L S P+ N G
Sbjct: 970 LVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEG 1029
Query: 391 DTII----------------------------------------------------FRDT 398
+I
Sbjct: 1030 TLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALSKYVWEEYGLLPSGSLRLAQV 1089
Query: 399 QISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSP 458
Q+ Y+C SN G ++ +V + VPP+ + P ++++V++ L+C G+P
Sbjct: 1090 QVGDSGHYECTASNPAG-SASHRYVLGVQVPPQ-VQPGPRVLKVLVGEALDLNCVAEGNP 1147
Query: 459 IPTLRWFKNG---QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR 515
P L W K+G QG GS+ IR D G Y C A+N G +V
Sbjct: 1148 EPQLSWSKDGVVLQGRG---------PQGSVHFAAIRTSDAGRYRCEASNSAGVDAWEVE 1198
Query: 516 LEVKDPTRIYRMPEDQVARR--GTTVQLECRVKHDPSLKLTVSWLK--DDEPLYIGNRMK 571
L V +P + R G L C + P K V+W K EPL+ +
Sbjct: 1199 LRVLEPPHWGADETSGLLERVAGENASLPCPARGTP--KPQVTWRKGPSSEPLHGQPGVA 1256
Query: 572 -KEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDR 630
E+ SL + V+ D G Y C A+ E+ +A L V +P +
Sbjct: 1257 VLEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVY------------VPPSIRED 1304
Query: 631 PRDLELTDLAERSVRLTWIPGDANNSPITDYV 662
R ++ +A +S+ L DAN P+ + V
Sbjct: 1305 GRKANVSGMAGQSLTLEC---DANGFPVPEIV 1333
Score = 143 bits (361), Expect = 9e-34
Identities = 154/581 (26%), Positives = 236/581 (40%), Gaps = 47/581 (8%)
Query: 37 LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 96
LT P + +A++ + ++ ++C G P P WT++ R + P + ++
Sbjct: 1404 LTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKD-RQPVLPGGPHLQVQEDG 1462
Query: 97 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSP-LWPKENLDPVVVQEG 155
L R G EG YQC A + G + +L+V P +W V V E
Sbjct: 1463 QVL----RITGSHVGDEGRYQCVAFSPAGQQ-ARDFQLRVHAPPTIWGSNETGEVAVMED 1517
Query: 156 APLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNA 215
+ L C G+P+P I W T K V L D Y+C A
Sbjct: 1518 HLVQLLCE-ARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGV-YTCKA 1575
Query: 216 RFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPT 275
N TR P+ G + G + LEC+A G P+
Sbjct: 1576 ----------SNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPS 1625
Query: 276 PDIAWYKKGGDLP---SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVR 332
P ++W+ +G LP S++++ E LR+ + E SG Y C+AS+ G SV
Sbjct: 1626 PTLSWHHEG--LPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVE 1683
Query: 333 VKAAPYWL--DEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVA- 389
V+ P L + + G+ L C+A+G+P PT+QW+ NG P + +VA
Sbjct: 1684 VQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEEL---AGVQVAS 1740
Query: 390 -GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLD--VPPRMLSPRNQLIRVILYN 446
G T+ ++ ++ C +NE G A VSV P + P Q ++
Sbjct: 1741 QGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHH 1800
Query: 447 RT---RLDCP----FFGSPIPTL--RWFKNGQGSNLDGGNYHVYE-NGSLEIKMIRKEDQ 496
+ D P + P P L W G G Y L+I+ + D+
Sbjct: 1801 SSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDE 1860
Query: 497 GIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVS 556
GIYTC ATN+ G+++ +V L+V P I P ++ +V LEC P VS
Sbjct: 1861 GIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVP--PPDVS 1918
Query: 557 WLKDDEPL--YIGNRMKKEDDSLTIFGVAERDQGSYTCVAS 595
W K +P+ ++G + + L I D GSY CVAS
Sbjct: 1919 WFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVAS 1959
Score = 143 bits (360), Expect = 1e-33
Identities = 145/562 (25%), Positives = 224/562 (39%), Gaps = 45/562 (8%)
Query: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
+ CE +G P P W ++ + + + G L+ G EG Y C
Sbjct: 2182 LSCECRGVPFPKISWRKDGQPLP-GEGAGLQHVSAVGRLLY---LGQAQLAQEGTYTCEC 2237
Query: 121 RNKFGTALSNRIRLQVSKSP--LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSS 178
N G + S ++L+V P P+E V V + TL+CN G P P + W
Sbjct: 2238 SNVVGNS-SQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNAT-GKPPPTVTWERD 2295
Query: 179 SMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRG 238
+P+ + + + G YSC A + ++K F L VL
Sbjct: 2296 G-QPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAE-NLAGRAERK--FELSVLVP-- 2349
Query: 239 VAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL-PSDKAKFENF 297
P + ++ L L C A G+P P I W++ + P +
Sbjct: 2350 -----PELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAG 2404
Query: 298 NKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA--PGEDGR 355
L++T E+DSG Y CLASN+ G R SV V P +E ++ G+
Sbjct: 2405 GWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAH 2464
Query: 356 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQ--ISSRAVYQCNTSNE 413
L+C G+P+P + W +G PL + ++ D ++ + Q +SS Y C +N
Sbjct: 2465 LMCNVTGHPQPKLTWFKDGRPLARGDAH---HISPDGVLLQVLQANLSSAGHYSCIAANA 2521
Query: 414 HGYLLANAFVSVLDVPPRMLSPRNQL---IRVILYNRTRLDCPFFGSPIPTLRWFKNGQG 470
G + +SVL P + + + V + N L C P P + W K+G
Sbjct: 2522 VGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAP 2581
Query: 471 SNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPED 530
+ L+I +KED G YTCV TN LG+A +EV P I + +D
Sbjct: 2582 FEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISK--DD 2639
Query: 531 QVARRG---------TTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK--KEDDSLTI 579
+ G +T+ LEC P T+ W KD +P+ +R++ E L I
Sbjct: 2640 PLGEVGVKEVKTKVNSTLTLECESWAVP--PPTIRWYKDGQPVTPSSRLQVLGEGRLLQI 2697
Query: 580 FGVAERDQGSYTCVASTELDQD 601
D G Y CVA+ +D
Sbjct: 2698 QPTQVSDSGRYLCVATNVAGED 2719
Score = 141 bits (356), Expect = 3e-33
Identities = 156/628 (24%), Positives = 253/628 (40%), Gaps = 86/628 (13%)
Query: 33 IQNELTQPPTIT-KQSAKDHIVDPRDNIL-IECEAKGNPAPSFHWTRNSRFFNIAKDPRV 90
+Q E+ PP I + + +D + +EC A G P P+ W R+ + + + +
Sbjct: 2248 LQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQ--PVGAELGL 2305
Query: 91 SMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKE---NL 147
++ + +L ++ + G Y C A N L+ R + S L P E +L
Sbjct: 2306 QLQNQGQSLHVERAQAA----HTGRYSCVAEN-----LAGRAERKFELSVLVPPELIGDL 2356
Query: 148 DPVVVQEGA---PLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVML 204
DP+ A PLTL C G+P P I W EP VS G + L ML
Sbjct: 2357 DPLTNITAALHSPLTLLCEAM-GIPPPAIRWFRGE-EP------VSPGEDTYLLAGGWML 2408
Query: 205 QDMQTD------YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMV 258
+ QT YSC A + + F+++VL P + + V
Sbjct: 2409 KMTQTQEQDSGLYSCLAS---NEAGEARRNFSVEVLV--------PPSIENEDLEEVIKV 2457
Query: 259 LRGMDLLLECIASGVPTPDIAWYKKGGDLP-SDKAKFENFNKALRITNVSEEDSGEYFCL 317
L G L C +G P P + W+K G L D L++ + +G Y C+
Sbjct: 2458 LDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCI 2517
Query: 318 ASNKMGSIRHTISVRVKAAPYWL-----DEPKNLILAPGEDGRLVCRANGNPKPTVQWMV 372
A+N +G + V AP L + + + L+C A P P + WM
Sbjct: 2518 AANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMK 2577
Query: 373 NGEPLQSAPPNPNREVAGDT--IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPP 430
+G P +++ N ++ T + + Q Y C +NE G + N V VL +PP
Sbjct: 2578 DGAPFEASR---NIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVL-IPP 2633
Query: 431 RMLS--PRNQL----IRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENG 484
+ P ++ ++ + + L+C + P PT+RW+K+GQ + E
Sbjct: 2634 SISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGR 2693
Query: 485 SLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYR----------MPEDQVAR 534
L+I+ + D G Y CVATN+ G+ + + ++ P + + ++ AR
Sbjct: 2694 LLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEAR 2753
Query: 535 RGTT----------VQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK--KEDDSLTIFGV 582
G T L C P LT W ++D+PL G+ + + L I V
Sbjct: 2754 GGVTEYREIVENNPAYLYCDTNAIPPPDLT--WYREDQPLSAGDEVSVLQGGRVLQIPLV 2811
Query: 583 AERDQGSYTCVASTELDQDLAKAYLTVL 610
+ G Y+C AS E+ +D L VL
Sbjct: 2812 RAENAGRYSCKASNEVGEDWLHYELLVL 2839
Score = 140 bits (352), Expect = 1e-32
Identities = 159/640 (24%), Positives = 242/640 (37%), Gaps = 92/640 (14%)
Query: 40 PPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTL 99
PP I + +++ + L G P P HW ++ R + R S+R G+L
Sbjct: 884 PPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGR--PLPPGSRHSIRA-DGSL 940
Query: 100 VIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPV----VVQEG 155
+D +E+ G Y C A N G+ + + L V P + P + EG
Sbjct: 941 HLDRAL----QEHAGRYSCVATNTAGSQHRD-VELVVQVPP-----RIHPTATHHITNEG 990
Query: 156 APLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNA 215
P +L C G+P+P I W + ++ + G L + QD Y C A
Sbjct: 991 VPASLPC-VASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGA-YVCTA 1048
Query: 216 RFHFTHTIQQKNPFTLKVLTTRGVAER---TPSFMY-------------------PQGTA 253
+ Q+ ++ ++ V E PS P G+A
Sbjct: 1049 TNTVGFSSQEMRLSVNRLALSKYVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSA 1108
Query: 254 SSQMVLR------------------GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFE 295
S + VL G L L C+A G P P ++W K G L +
Sbjct: 1109 SHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGS 1168
Query: 296 NFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYW-LDEPKNLI-LAPGED 353
A+R + D+G Y C ASN G + +RV P+W DE L+ GE+
Sbjct: 1169 VHFAAIRTS-----DAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGEN 1223
Query: 354 GRLVCRANGNPKPTVQWM--VNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTS 411
L C A G PKP V W + EPL P E ++ + Y+C +
Sbjct: 1224 ASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEG--SLFLASVSPADSGDYECQAT 1281
Query: 412 NEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQ-- 469
NE G A + V P R + + L+C G P+P + W K+ Q
Sbjct: 1282 NEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLV 1341
Query: 470 -------------GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL 516
G GG+ + E SL I++ D G+Y+C A N G A+ L
Sbjct: 1342 GVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHL 1401
Query: 517 EVKDPTRIY--RMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGN---RMK 571
V P + ++ + G V+L+C P+ + V W KD +P+ G +++
Sbjct: 1402 LVLTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQ--VEWTKDRQPVLPGGPHLQVQ 1459
Query: 572 KEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLA 611
++ L I G D+G Y CVA + Q L V A
Sbjct: 1460 EDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHA 1499
Score = 135 bits (341), Expect = 2e-31
Identities = 125/495 (25%), Positives = 203/495 (41%), Gaps = 31/495 (6%)
Query: 40 PPTITKQSAKDHIVDPR-DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPR-----VSMR 93
PP+I + K ++ ++ +EC+A G P P W ++++ + +
Sbjct: 1298 PPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWG 1357
Query: 94 RRSGTLVIDF-RSGGRPEEYEGE---YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP 149
+ G ++D +S P EG+ Y C A N+ GTA + L ++ +
Sbjct: 1358 QVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQE 1417
Query: 150 VVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 209
V+ GA + LQC G+P+P + W + + +G + +
Sbjct: 1418 VLGLAGADVELQCWTS-GVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEG 1476
Query: 210 DYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECI 269
Y C A F+ QQ F L+V P ++ V+ + L C
Sbjct: 1477 RYQCVA---FSPAGQQARDFQLRV--------HAPPTIWGSNETGEVAVMEDHLVQLLCE 1525
Query: 270 ASGVPTPDIAWYKKGGDLP-SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHT 328
A GVPTP+I W+K G LP S K + + L++ D+G Y C ASN +G+
Sbjct: 1526 ARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKA 1585
Query: 329 ISVRVKAAPYWLD---EPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPN 385
+ V P P + G L C A G+P PT+ W G P+ A N +
Sbjct: 1586 TRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPV--AESNES 1643
Query: 386 R-EVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQ-LIRVI 443
R E G + +S +Y C S+ G + V V VPP++L + I
Sbjct: 1644 RLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEV-QVPPQLLVAEGLGQVTTI 1702
Query: 444 LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 503
+ L C GSP+PT++W +NG+ + G + +L I + + G++ C A
Sbjct: 1703 VGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQA 1762
Query: 504 TNILGKAENQVRLEV 518
TN G A +V + V
Sbjct: 1763 TNEAGTAGAEVEVSV 1777
Score = 132 bits (333), Expect = 2e-30
Identities = 153/607 (25%), Positives = 230/607 (37%), Gaps = 88/607 (14%)
Query: 25 IEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNI 84
+++P + L Q TI Q + + C+A G+P P+ W +N R
Sbjct: 1684 VQVPPQLLVAEGLGQVTTIVGQPLE-----------LPCQASGSPVPTIQWLQNGR--PA 1730
Query: 85 AKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPK 144
+ V + + TL ID ++ G + C A N+ GTA + ++VS W
Sbjct: 1731 EELAGVQVASQGTTLHIDHVE----LDHSGLFACQATNEAGTAGAE---VEVSVHGEWAP 1783
Query: 145 ENLDPVVVQ------EGAPLTLQCNPP--------------PGLPSPVIFWMSSSMEPIT 184
L+ + Q + C+PP G SP W + P
Sbjct: 1784 GVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIP-- 1841
Query: 185 QDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTP 244
V+ L V L+D + Y+C A + K LKVL +
Sbjct: 1842 ----VAYSLPPPLQIEKVDLRD-EGIYTCAAT---NLAGESKREVALKVLVPPNI----- 1888
Query: 245 SFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFN-KALRI 303
+ ++ VL + LEC+ASGVP PD++W+K + S + + + LRI
Sbjct: 1889 -----EPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRI 1943
Query: 304 TNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDG--------R 355
D+G Y C+ASN GS +RV P + L P G R
Sbjct: 1944 EQAQLSDAGSYRCVASNVAGSTELRYGLRVNV-------PPRITLPPSLPGPVLVNTPVR 1996
Query: 356 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTIIFRDTQISSRAVYQCNTSNE 413
L C A G P PT+ W+ +G P+ A P +V G + + S Y C +
Sbjct: 1997 LTCNATGAPSPTLMWLKDGNPVSPA-GTPGLQVFPGGRVLTLASARASDSGRYSCVAVSA 2055
Query: 414 HGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNL 473
G + + V +PP +L + V+ L+C P P L W+K+G+
Sbjct: 2056 VGEDRQDVVLQV-HMPPSILGEELN-VSVVANESVALECQSHAMPPPVLSWWKDGRPLEP 2113
Query: 474 DGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV-KDPTRIYRMPEDQV 532
G + + L++ D G YTC A N G +E L V P R
Sbjct: 2114 RPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLT 2173
Query: 533 ARRGTTVQLECRVKHDPSLKLTVSWLKDDEPL---YIGNRMKKEDDSLTIFGVAE-RDQG 588
R G L C + P K +SW KD +PL G + L G A+ +G
Sbjct: 2174 VREGHPTSLSCECRGVPFPK--ISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEG 2231
Query: 589 SYTCVAS 595
+YTC S
Sbjct: 2232 TYTCECS 2238
Score = 131 bits (329), Expect = 5e-30
Identities = 151/585 (25%), Positives = 241/585 (41%), Gaps = 51/585 (8%)
Query: 57 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 116
+N + C A+G P P W + + P V++ G+L F + P + G+Y
Sbjct: 1222 ENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEE-GSL---FLASVSPAD-SGDY 1276
Query: 117 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVV-QEGAPLTLQCNPPPGLPSPVIFW 175
+C A N+ G+ S R +L V P ++ V G LTL+C+ G P P I W
Sbjct: 1277 ECQATNEVGST-SRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDAN-GFPVPEIVW 1334
Query: 176 MSSSMEPITQDKRVSQGHNGDLYFSNV----MLQDMQTDYSCNARFHFTHTIQQKNP--F 229
+ + + G+ DL + V +L + Q+ HF IQ+ + +
Sbjct: 1335 LKDAQ--LVGVPLGWAGYGWDLGWGQVGGHRLLDEGQS-------LHFPR-IQEGDSGLY 1384
Query: 230 TLKVLTTRGVAER-------TPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYK 282
+ + G A+R TP + G A + L G D+ L+C SGVPTP + W K
Sbjct: 1385 SCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTK 1444
Query: 283 -KGGDLPSDK-AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWL 340
+ LP + + + LRIT D G Y C+A + G +RV A P
Sbjct: 1445 DRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIW 1504
Query: 341 DEPKNLILAPGEDG--RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV---AGDTIIF 395
+ +A ED +L+C A G P P + W +G L P + V G +
Sbjct: 1505 GSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALL----PTSTKVVYTRGGRQLQL 1560
Query: 396 RDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRM--LSPRNQLIRVILYNRTRLDCP 453
Q S VY C SN G + V VPP + R +++ + L+C
Sbjct: 1561 GRAQSSDAGVYTCKASNAVGAAEKATRLDVY-VPPTIEGAGGRPYVVKAVAGRPVALECV 1619
Query: 454 FFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQ 513
G P PTL W G + + L ++ + G+Y+CVA++ G+A Q
Sbjct: 1620 ARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQ 1679
Query: 514 VRLEVKDPTRIYRMPE-DQVAR-RGTTVQLECRVKHDPSLKLTVSWLKDDEPL--YIGNR 569
+EV+ P ++ QV G ++L C+ P T+ WL++ P G +
Sbjct: 1680 YSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSP--VPTIQWLQNGRPAEELAGVQ 1737
Query: 570 MKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQA 614
+ + +L I V G + C A+ E A+ ++V + A
Sbjct: 1738 VASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWA 1782
Score = 119 bits (297), Expect = 2e-26
Identities = 102/396 (25%), Positives = 173/396 (43%), Gaps = 32/396 (8%)
Query: 37 LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 96
+ Q P + + D + + C+A+G+P P+ W ++ + + A+ + S
Sbjct: 4033 VVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTI--QPS 4090
Query: 97 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGA 156
G L++ G + G Y C A N G A R+ L + P++ D + + G
Sbjct: 4091 GELLVKNLEG----QDAGTYTCTAENAVGRA-RRRVHLTILVLPVFTTLPGDRSL-RLGD 4144
Query: 157 PLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNA- 215
L L+C G P+P I W + P+T+ VS+ G + ++ Y C A
Sbjct: 4145 RLWLRC-AARGSPTPRIGWTVND-RPVTEG--VSEQDGGSTLQRAAVSREDSGTYVCWAE 4200
Query: 216 -RFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLR-GMDLLLECIASGV 273
R T + + VL QG A S +V G + L+C+ G
Sbjct: 4201 NRVGRTQAVSFVHVKEAPVL---------------QGEAFSYLVEPVGGSIQLDCVVRGD 4245
Query: 274 PTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRV 333
P PDI W K G L + + N +L I +D+G Y CLA N+MG + + + +
Sbjct: 4246 PVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVL 4305
Query: 334 KAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTI 393
++AP + EP+++ + G+D L C+A G P PT++W+ G+PL+++ R + ++
Sbjct: 4306 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRAS--RRLRTLPDGSL 4363
Query: 394 IFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVP 429
+ + Y C N G A AF+ V P
Sbjct: 4364 WLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEP 4399
Score = 115 bits (288), Expect = 3e-25
Identities = 125/494 (25%), Positives = 193/494 (39%), Gaps = 50/494 (10%)
Query: 39 QPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGT 98
+ P ++ ++ H + + + C A G P P W+R S+ + +D R+ + + GT
Sbjct: 606 EAPQVSIHTSSQHFSQGVE-VKVSCSASGYPTPHISWSRESQA--LQEDSRIHVDAQ-GT 661
Query: 99 LVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPL 158
L+I G PE+ G Y C A N+ GT + L + P N V+V G
Sbjct: 662 LIIQ---GVAPED-AGNYSCQATNEVGTD-QETVTLYYTDPPSVSAVNA-VVLVAVGEEA 715
Query: 159 TLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFH 218
L C G+P P + W +E I + S +G L +D T Y+C A
Sbjct: 716 VLVCEAS-GVPPPRVIWYRGGLEMILAPEGSS---SGKLRIPAAQERDAGT-YTCRA--- 767
Query: 219 FTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDI 278
+ + + ++ G A + P+ V G LL C A+G P P +
Sbjct: 768 ----VNELGDASAEIQLAVGHAPQLTEL--PRDVT----VELGRSALLACRATGRPPPTV 817
Query: 279 AWYKKGGD-------LPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISV 331
W + G + + L +V+ ED Y C A N G ++ +
Sbjct: 818 TWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARL 877
Query: 332 RVK--AAPYWLDEPKNLILAPGEDGRLVCRA-NGNPKPTVQWMVNGEPLQSAPPNPNREV 388
V A P + + G+ L C G P P W+ +G PL PP +
Sbjct: 878 IVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPL---PPGSRHSI 934
Query: 389 AGDTIIFRDTQISSRAV-YQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNR 447
D + D + A Y C +N G + + V+ VPPR+ I N
Sbjct: 935 RADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVEL-VVQVPPRIHPTATHHIT----NE 989
Query: 448 ---TRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVAT 504
L C G P PT+ W K G +Y+V + G+L I +D G Y C AT
Sbjct: 990 GVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTAT 1049
Query: 505 NILGKAENQVRLEV 518
N +G + ++RL V
Sbjct: 1050 NTVGFSSQEMRLSV 1063
Score = 95.5 bits (236), Expect = 3e-19
Identities = 88/336 (26%), Positives = 136/336 (40%), Gaps = 12/336 (3%)
Query: 295 ENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDG 354
E+ N + I S+ + G Y C A ++ G+ R + V P L N+ ++PGE
Sbjct: 475 ESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETA 534
Query: 355 RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNR--EVAGDTIIFRDTQISSRAVYQCNTSN 412
L CR G + W+ + L P + R ++A ++ + YQC SN
Sbjct: 535 VLSCRVLGEAPYNLTWVRDWRVL---PASTGRVAQLADLSLEISGIIPTDGGRYQCVASN 591
Query: 413 EHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSN 472
+G A+ ++ V + P + +Q + ++ C G P P + W + Q
Sbjct: 592 ANGVTRASVWLLVREAPQVSIHTSSQHFSQGV--EVKVSCSASGYPTPHISWSRESQALQ 649
Query: 473 LDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQV 532
D HV G+L I+ + ED G Y+C ATN +G + V L DP + + +
Sbjct: 650 ED-SRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVL 708
Query: 533 ARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTC 592
G L C P + V W + + + L I ERD G+YTC
Sbjct: 709 VAVGEEAVLVCEASGVPPPR--VIWYRGGLEMILAPE-GSSSGKLRIPAAQERDAGTYTC 765
Query: 593 VASTELDQDLAKAYLTV-LADQATPTNRLAALPKGR 627
A EL A+ L V A Q T R + GR
Sbjct: 766 RAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGR 801
Score = 54.3 bits (129), Expect = 7e-07
Identities = 43/155 (27%), Positives = 62/155 (40%), Gaps = 4/155 (2%)
Query: 457 SPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL 516
S +P + G+ + ++ N S EI K ++G Y C A + G + ++
Sbjct: 452 SALPFRLQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQI 511
Query: 517 EVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDE--PLYIGNRMKKED 574
V DP + G T L CRV + LT W++D P G + D
Sbjct: 512 VVTDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLT--WVRDWRVLPASTGRVAQLAD 569
Query: 575 DSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
SL I G+ D G Y CVAS A +L V
Sbjct: 570 LSLEISGIIPTDGGRYQCVASNANGVTRASVWLLV 604
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,794,053
Number of Sequences: 37866
Number of extensions: 2748785
Number of successful extensions: 33331
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 436
Number of HSP's successfully gapped in prelim test: 437
Number of HSP's that attempted gapping in prelim test: 9136
Number of HSP's gapped (non-prelim): 9399
length of query: 1240
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1126
effective length of database: 13,930,794
effective search space: 15686074044
effective search space used: 15686074044
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.