Search of human proteins with 237649104

Search of human proteins with 237649104

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]
         (597 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]       1198   0.0  
gi|242247075 bromodomain containing 9 isoform 2 [Homo sapiens]        882   0.0  
gi|41350212 bromodomain containing 7 [Homo sapiens]                   349   5e-96
gi|11321642 bromodomain containing protein 1 [Homo sapiens]            97   3e-20
gi|239753965 PREDICTED: zinc finger, DHHC-type containing 11B [H...    86   1e-16
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi...    77   5e-14
gi|51173722 bromodomain and PHD finger-containing protein 1 isof...    75   2e-13
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ...    69   9e-12
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    69   9e-12
gi|51173720 bromodomain and PHD finger-containing protein 1 isof...    69   2e-11
gi|50345997 E1A binding protein p300 [Homo sapiens]                    67   4e-11
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    64   4e-10
gi|38788260 bromodomain PHD finger transcription factor isoform ...    62   1e-09
gi|38788274 bromodomain PHD finger transcription factor isoform ...    62   1e-09
gi|164419758 bromodomain containing 2 [Homo sapiens]                   60   4e-09
gi|4826806 bromodomain containing 2 [Homo sapiens]                     60   4e-09
gi|119943102 CREB binding protein isoform b [Homo sapiens]             60   7e-09
gi|119943104 CREB binding protein isoform a [Homo sapiens]             60   7e-09
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r...    59   1e-08
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r...    59   1e-08
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r...    59   1e-08
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re...    59   1e-08
gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens]          59   1e-08
gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens]          59   1e-08
gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens]          59   1e-08
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r...    59   1e-08
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r...    59   1e-08
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo...    59   1e-08
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r...    59   2e-08
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo...    59   2e-08

>gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]
          Length = 597

 Score = 1198 bits (3100), Expect = 0.0
 Identities = 597/597 (100%), Positives = 597/597 (100%)

Query: 1   MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHER 60
           MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHER
Sbjct: 1   MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHER 60

Query: 61  ERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEP 120
           ERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEP
Sbjct: 61  ERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEP 120

Query: 121 PPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP 180
           PPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP
Sbjct: 121 PPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP 180

Query: 181 MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQ 240
           MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQ
Sbjct: 181 MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQ 240

Query: 241 AALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVL 300
           AALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVL
Sbjct: 241 AALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVL 300

Query: 301 ALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLS 360
           ALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLS
Sbjct: 301 ALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLS 360

Query: 361 SKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQ 420
           SKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQ
Sbjct: 361 SKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQ 420

Query: 421 CALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLG 480
           CALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLG
Sbjct: 421 CALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLG 480

Query: 481 DSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAE 540
           DSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAE
Sbjct: 481 DSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAE 540

Query: 541 RGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT 597
           RGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT
Sbjct: 541 RGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT 597


>gi|242247075 bromodomain containing 9 isoform 2 [Homo sapiens]
          Length = 544

 Score =  882 bits (2279), Expect = 0.0
 Identities = 461/547 (84%), Positives = 481/547 (87%), Gaps = 21/547 (3%)

Query: 61  ERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDP---GKKVE 117
           ER  +K+K+++++S + + +     RK   E+KR+   E   T    +       G++  
Sbjct: 9   ERGTKKRKRRRRRSPRRRSI--WTMRKEGSERKRRSGSERGSTVTRRERLTTLILGRRWR 66

Query: 118 VEPPP-DRPVRACRTQPAENESTPIQQLLEHFLRQLQR------KDPHGFFAFPVTDAIA 170
              P   +  RA  +QP         ++  H             +DPHGFFAFPVTDAIA
Sbjct: 67  WSRPQIGQSERAGHSQP---------KMRAHLFSNSWNTSSASFRDPHGFFAFPVTDAIA 117

Query: 171 PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKIL 230
           PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKIL
Sbjct: 118 PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKIL 177

Query: 231 HAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSL 290
           HAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSL
Sbjct: 178 HAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSL 237

Query: 291 TDSTAEEHVLALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEE 350
           TDSTAEEHVLALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEE
Sbjct: 238 TDSTAEEHVLALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEE 297

Query: 351 THPVDLSSLSSKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLY 410
           THPVDLSSLSSKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLY
Sbjct: 298 THPVDLSSLSSKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLY 357

Query: 411 SAYGDETGVQCALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPP 470
           SAYGDETGVQCALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPP
Sbjct: 358 SAYGDETGVQCALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPP 417

Query: 471 DEAKVGDTLGDSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKL 530
           DEAKVGDTLGDSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKL
Sbjct: 418 DEAKVGDTLGDSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKL 477

Query: 531 LQDLHEAQAERGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPE 590
           LQDLHEAQAERGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPE
Sbjct: 478 LQDLHEAQAERGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPE 537

Query: 591 PAASAKT 597
           PAASAKT
Sbjct: 538 PAASAKT 544


>gi|41350212 bromodomain containing 7 [Homo sapiens]
          Length = 651

 Score =  349 bits (895), Expect = 5e-96
 Identities = 215/606 (35%), Positives = 340/606 (56%), Gaps = 66/606 (10%)

Query: 1   MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELS--GSGHDSSYYDDRSDH 58
           MGKKHKKHK++ +  YE+Y    +EKPLKLVLKVGG+EVTELS   SGHDSS ++D++DH
Sbjct: 1   MGKKHKKHKSD-KHLYEEY----VEKPLKLVLKVGGNEVTELSTGSSGHDSSLFEDKNDH 55

Query: 59  ERERHKEKKKKKKKKSEKEKHLDDEERRKRK-EEKKRKREREHCDTEGEADDFDPGKKVE 117
           ++  HK++K+KK+KK EK+   +++ R++R+ +E K+KR+R+  + E E D       V 
Sbjct: 56  DK--HKDRKRKKRKKGEKQIPGEEKGRKRRRVKEDKKKRDRDRVENEAEKD-LQCHAPVR 112

Query: 118 VEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMII 177
           ++ PP++P+ +   +  E E TP+Q+ L   +RQLQRKDP  FF+FPVTD IAPGYSMII
Sbjct: 113 LDLPPEKPLTSSLAKQEEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMII 172

Query: 178 KHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMM 237
           KHPMDF TMK+KI  N+Y+S+ E K +FKLMC NAM YN+P+T+YYK AKK+LH+G K++
Sbjct: 173 KHPMDFSTMKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKIL 232

Query: 238 SKQ--------------------------AALLGNEDTAVEEPVPEVVPVQVETAKKSKK 271
           S++                           +  G +    +    +    +    K   K
Sbjct: 233 SQERIQSLKQSIDFMADLQKTRKQKDGTDTSQSGEDGGCWQREREDSGDAEAHAFKSPSK 292

Query: 272 PSREVISCMFEPEGNACSLTDSTAEEHVLALVEHAADEARDRINRFLPGGKMGYLKRNGD 331
            +++    M E +  + +L      E     ++    E+  ++ R L   +  + +R  D
Sbjct: 293 ENKKKDKDMLEDKFKSNNL------EREQEQLDRIVKESGGKLTRRLVNSQCEFERRKPD 346

Query: 332 GSLLYSVVNTAEPDADEEETHPVDLSSLSSKLLPGFTTL-GFKDERRNKVT---FLS-SA 386
           G+    +++  +P   E    PV L   + +L  G  TL GFK+++RNKVT   +L+   
Sbjct: 347 GTTTLGLLHPVDPIVGEPGYCPVRLGMTTGRLQSGVNTLQGFKEDKRNKVTPVLYLNYGP 406

Query: 387 TTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQCALSLQEFVKDAGSYSKKVVDDLLDQ 446
            ++ +   +S F ++  D+ +L+YS YG+++ +    S+ EF+     Y   + D LLD 
Sbjct: 407 YSSYAPHYDSTFANISKDDSDLIYSTYGEDSDLPSDFSIHEFLATCQDYPYVMADSLLDV 466

Query: 447 ITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLGDSSSSVLEFMSMK-------SYPDVS 499
           +T G HSRTL +++        P DE   G T    ++  +E   ++       S  D  
Sbjct: 467 LTKGGHSRTLQEMEM-----SLPEDE---GHTRTLDTAKEMEITEVEPPGRLDSSTQDRL 518

Query: 500 VDISMLSSLGKVKKELDPDDSHL---NLDETTKLLQDLHEAQAERGGSRPSSNLSSLSNA 556
           + +  +++ G   +  D +++ +    LDETT+LL++L EAQ ER  +RP  N+  L   
Sbjct: 519 IALKAVTNFGVPVEVFDSEEAEIFQKKLDETTRLLRELQEAQNERLSTRPPPNMICLLGP 578

Query: 557 SERDQH 562
           S R+ H
Sbjct: 579 SYREMH 584


>gi|11321642 bromodomain containing protein 1 [Homo sapiens]
          Length = 1058

 Score = 97.4 bits (241), Expect = 3e-20
 Identities = 67/185 (36%), Positives = 90/185 (48%), Gaps = 23/185 (12%)

Query: 49  SSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEAD 108
           SS    RS  +RE  +E K  K+K    ++   D ER +   E  RKRE+   +      
Sbjct: 498 SSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIELLRKREKLKRE------ 551

Query: 109 DFDPGKKVEVEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDA 168
                 +V+VE               E   TP+  LL   L QLQ KDP   FA PV+  
Sbjct: 552 ------QVKVEQVA-----------MELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLK 594

Query: 169 IAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKK 228
             P Y   IKHPMDF TM+ ++ A  YK++ EF+ DF L+ DN M YN  DTV+Y+ A +
Sbjct: 595 EVPDYLDHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVR 654

Query: 229 ILHAG 233
           +   G
Sbjct: 655 LRDQG 659


>gi|239753965 PREDICTED: zinc finger, DHHC-type containing 11B [Homo
           sapiens]
          Length = 573

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 42/49 (85%), Positives = 44/49 (89%)

Query: 375 ERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQCAL 423
           + R  VTFLSSATT LSMQNNS FGDLKSDE+ELLYSAYGDETGVQCAL
Sbjct: 7   DARAPVTFLSSATTTLSMQNNSAFGDLKSDELELLYSAYGDETGVQCAL 55


>gi|148727368 bromodomain and PHD finger containing, 3 [Homo
           sapiens]
          Length = 1205

 Score = 77.0 bits (188), Expect = 5e-14
 Identities = 55/185 (29%), Positives = 85/185 (45%), Gaps = 23/185 (12%)

Query: 49  SSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEAD 108
           S     R+  +RE+ ++    K++    +K   D ER +   E  RKRE+          
Sbjct: 525 SHLQSQRNAEQREQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKL--------- 575

Query: 109 DFDPGKKVEVEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDA 168
                K+ +V+          +    E E  P   LL   L  LQ KDP   FA PV  +
Sbjct: 576 -----KREQVK---------VQQAAMELELMPFNVLLRTTLDLLQEKDPAHIFAEPVNLS 621

Query: 169 IAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKK 228
             P Y   I  PMDF TM+ K+ ++ Y+++ EF+ DF L+  N M YN  DT++++ A +
Sbjct: 622 EVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYNAKDTIFHRAAVR 681

Query: 229 ILHAG 233
           +   G
Sbjct: 682 LRDLG 686


>gi|51173722 bromodomain and PHD finger-containing protein 1 isoform
           2 [Homo sapiens]
          Length = 1214

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 42/114 (36%), Positives = 59/114 (51%), Gaps = 3/114 (2%)

Query: 135 ENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANE 194
           E + TP   LL   L QLQ KD    F+ PV  +  P Y   IK PMDF TMK  + A  
Sbjct: 627 EMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYR 686

Query: 195 YKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAG---FKMMSKQAALLG 245
           Y +  +F+ DF L+  N + YN  DT++Y+ A ++   G    +   +QA  +G
Sbjct: 687 YLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMG 740


>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
           sapiens]
          Length = 722

 Score = 69.3 bits (168), Expect = 9e-12
 Identities = 63/193 (32%), Positives = 89/193 (46%), Gaps = 18/193 (9%)

Query: 121 PPDRPVRACRTQPAENESTPIQQLLE---HFLRQLQRKDPHGFFAFPV---TDAIAPG-- 172
           PP + V   +  PA  +S+ + + L+     L+++  K  H  +A+P     D  A G  
Sbjct: 330 PPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKK-HAAYAWPFYKPVDVEALGLH 388

Query: 173 -YSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILH 231
            Y  IIKHPMD  T+K K+ A EY+   EF AD +LM  N   YN PD     +A+K L 
Sbjct: 389 DYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARK-LQ 447

Query: 232 AGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLT 291
             F+M   + A + +E    EEPV  V    V    K   P     S   +   ++ S T
Sbjct: 448 DVFEM---RFAKMPDEP---EEPVVAVSSPAVPPPTKVVAPPSSSDSSS-DSSSDSDSST 500

Query: 292 DSTAEEHVLALVE 304
           D + EE    L E
Sbjct: 501 DDSEEERAQRLAE 513



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 50/179 (27%), Positives = 77/179 (43%), Gaps = 22/179 (12%)

Query: 112 PGKKVEVEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIA- 170
           P       PPP  P  +   +P + ++  +Q LL   L+ L +      F  PV DA+  
Sbjct: 37  PANAASTNPPP--PETSNPNKP-KRQTNQLQYLLRVVLKTLWKHQFAWPFQQPV-DAVKL 92

Query: 171 --PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRP--DTVYY--K 224
             P Y  IIK PMD GT+K ++  N Y +  E   DF  M  N   YN+P  D V     
Sbjct: 93  NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEA 152

Query: 225 LAKKILHAGFKMMSKQAALL---------GNEDTAVEEPVPEVVP--VQVETAKKSKKP 272
           L K  L    ++ +++  ++         G ++T   +P    VP   Q  T  +++ P
Sbjct: 153 LEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTP 211



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 31/122 (25%), Positives = 58/122 (47%), Gaps = 10/122 (8%)

Query: 27  PLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERR 86
           P K+V     S+ +  S S  DSS  DD  +   +R  E +++ K   E+   L   ++ 
Sbjct: 476 PTKVVAPPSSSDSSSDSSSDSDSST-DDSEEERAQRLAELQEQLKAVHEQLAALSQPQQN 534

Query: 87  KRKEEKKRKREREHCDTEGEADDFDPGKKVEV-EPPPDRPVR-------ACRTQPAENES 138
           K K+++K K+E++  +     ++ +  KK +  EPPP +  +         + +PA  +S
Sbjct: 535 KPKKKEKDKKEKKK-EKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKS 593

Query: 139 TP 140
            P
Sbjct: 594 KP 595



 Score = 33.5 bits (75), Expect = 0.57
 Identities = 20/87 (22%), Positives = 43/87 (49%), Gaps = 2/87 (2%)

Query: 37  SEVTELSGSGHDSSYYDDRSDHERERHKEK-KKKKKKKSEKEKHLDDEERRKRKEEKKRK 95
           +E+ E   + H+      +    + + KEK KK+KKK+  K K   +E ++ + +E   K
Sbjct: 512 AELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPK 571

Query: 96  REREHCDTEGEADDFDPGKKVEVEPPP 122
           + +++  +       +P   ++ +PPP
Sbjct: 572 KTKKNNSSNSNVSKKEPA-PMKSKPPP 597


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 69.3 bits (168), Expect = 9e-12
 Identities = 63/193 (32%), Positives = 89/193 (46%), Gaps = 18/193 (9%)

Query: 121 PPDRPVRACRTQPAENESTPIQQLLE---HFLRQLQRKDPHGFFAFPV---TDAIAPG-- 172
           PP + V   +  PA  +S+ + + L+     L+++  K  H  +A+P     D  A G  
Sbjct: 330 PPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKK-HAAYAWPFYKPVDVEALGLH 388

Query: 173 -YSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILH 231
            Y  IIKHPMD  T+K K+ A EY+   EF AD +LM  N   YN PD     +A+K L 
Sbjct: 389 DYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARK-LQ 447

Query: 232 AGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLT 291
             F+M   + A + +E    EEPV  V    V    K   P     S   +   ++ S T
Sbjct: 448 DVFEM---RFAKMPDEP---EEPVVAVSSPAVPPPTKVVAPPSSSDSSS-DSSSDSDSST 500

Query: 292 DSTAEEHVLALVE 304
           D + EE    L E
Sbjct: 501 DDSEEERAQRLAE 513



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 50/179 (27%), Positives = 77/179 (43%), Gaps = 22/179 (12%)

Query: 112 PGKKVEVEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIA- 170
           P       PPP  P  +   +P + ++  +Q LL   L+ L +      F  PV DA+  
Sbjct: 37  PANAASTNPPP--PETSNPNKP-KRQTNQLQYLLRVVLKTLWKHQFAWPFQQPV-DAVKL 92

Query: 171 --PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRP--DTVYY--K 224
             P Y  IIK PMD GT+K ++  N Y +  E   DF  M  N   YN+P  D V     
Sbjct: 93  NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEA 152

Query: 225 LAKKILHAGFKMMSKQAALL---------GNEDTAVEEPVPEVVP--VQVETAKKSKKP 272
           L K  L    ++ +++  ++         G ++T   +P    VP   Q  T  +++ P
Sbjct: 153 LEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTP 211



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 31/122 (25%), Positives = 58/122 (47%), Gaps = 10/122 (8%)

Query: 27  PLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERR 86
           P K+V     S+ +  S S  DSS  DD  +   +R  E +++ K   E+   L   ++ 
Sbjct: 476 PTKVVAPPSSSDSSSDSSSDSDSST-DDSEEERAQRLAELQEQLKAVHEQLAALSQPQQN 534

Query: 87  KRKEEKKRKREREHCDTEGEADDFDPGKKVEV-EPPPDRPVR-------ACRTQPAENES 138
           K K+++K K+E++  +     ++ +  KK +  EPPP +  +         + +PA  +S
Sbjct: 535 KPKKKEKDKKEKKK-EKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKS 593

Query: 139 TP 140
            P
Sbjct: 594 KP 595



 Score = 33.5 bits (75), Expect = 0.57
 Identities = 20/87 (22%), Positives = 43/87 (49%), Gaps = 2/87 (2%)

Query: 37  SEVTELSGSGHDSSYYDDRSDHERERHKEK-KKKKKKKSEKEKHLDDEERRKRKEEKKRK 95
           +E+ E   + H+      +    + + KEK KK+KKK+  K K   +E ++ + +E   K
Sbjct: 512 AELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPK 571

Query: 96  REREHCDTEGEADDFDPGKKVEVEPPP 122
           + +++  +       +P   ++ +PPP
Sbjct: 572 KTKKNNSSNSNVSKKEPA-PMKSKPPP 597


>gi|51173720 bromodomain and PHD finger-containing protein 1 isoform
           1 [Homo sapiens]
          Length = 1220

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 43/121 (35%), Positives = 60/121 (49%), Gaps = 11/121 (9%)

Query: 135 ENESTPIQQLLEHFLRQLQRKDPHGFFAFPVT-------DAIAPGYSMIIKHPMDFGTMK 187
           E + TP   LL   L QLQ KD    F+ PV        D + P Y   IK PMDF TMK
Sbjct: 627 EMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVTELDEV-PDYLDHIKKPMDFFTMK 685

Query: 188 DKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAG---FKMMSKQAALL 244
             + A  Y +  +F+ DF L+  N + YN  DT++Y+ A ++   G    +   +QA  +
Sbjct: 686 QNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKM 745

Query: 245 G 245
           G
Sbjct: 746 G 746


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 51/177 (28%), Positives = 81/177 (45%), Gaps = 12/177 (6%)

Query: 65   EKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEG-EADDFDPGKKVEVEPPPD 123
            EK+  ++ K E +  +D  E    + E   + + E C  E  E ++     K E++   D
Sbjct: 969  EKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEED 1028

Query: 124  RP-VRACRTQPAENESTP-------IQQLLEHFLRQLQRKDPHGF-FAFPVTDAIA--PG 172
            +P   A ++ PA  +S         ++Q L   L  L R+DP    F  PV   +   P 
Sbjct: 1029 QPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPD 1088

Query: 173  YSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKI 229
            Y  I+K PMD  T+K K+   +Y+   ++  D  LM +NA  YNR  +  YK   K+
Sbjct: 1089 YFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKL 1145


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
            sapiens]
          Length = 2168

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 44/165 (26%), Positives = 72/165 (43%), Gaps = 26/165 (15%)

Query: 64   KEKKKKKKKKSEKEKHLDDEE--------RRKRKEEKKRKREREHCDTEGEADDFDPGKK 115
            K  + KK KK       +DE+        +R  K+ KKRK E        + + F   KK
Sbjct: 1998 KTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKMEENTSINLSKQESFTSVKK 2057

Query: 116  VEVEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSM 175
                             P  ++S  +  L    L +++  +    F  PV   + PGY  
Sbjct: 2058 -----------------PKRDDSKDLA-LCSMILTEMETHEDAWPFLLPVNLKLVPGYKK 2099

Query: 176  IIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDT 220
            +IK PMDF T+++K+ + +Y ++  F  D +L+ DN  T+N  D+
Sbjct: 2100 VIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDS 2144



 Score = 32.7 bits (73), Expect = 0.97
 Identities = 20/75 (26%), Positives = 41/75 (54%), Gaps = 8/75 (10%)

Query: 59   ERERHKE-----KKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPG 113
            ERER ++     K  + +KK+E+++ L  E+R +++  K+RK E+   + E   +   P 
Sbjct: 1004 ERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPN 1063

Query: 114  KKV---EVEPPPDRP 125
            + +   + +P P+ P
Sbjct: 1064 EDMCLADQKPLPELP 1078



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 10/46 (21%)

Query: 65   EKKKKKKKKSEKEKHLDDEERRKRKE----------EKKRKREREH 100
            E KKKKK+++   K L+ E+R K KE           ++R+R R+H
Sbjct: 966  EAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQH 1011


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
            [Homo sapiens]
          Length = 2903

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 53/188 (28%), Positives = 82/188 (43%), Gaps = 24/188 (12%)

Query: 60   RERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPG------ 113
            ++R +E++K    KS+K+K +        KE KK  +    C T  +   F  G      
Sbjct: 2692 QKRKREEEKDSSSKSKKKKMISTTS----KETKKDTKLYCICKTPYDESKFYIGCDRCQN 2747

Query: 114  ---------KKVEVEPPPDRPVRACR-TQPAENESTPIQQL----LEHFLRQLQRKDPHG 159
                      + E E   +     C+ T+ A    TP+ +     L+  LR LQ      
Sbjct: 2748 WYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAW 2807

Query: 160  FFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPD 219
             F  PV    AP Y  +IK PMD  TM++++    Y+ +TEF AD   + DN   YN  D
Sbjct: 2808 PFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSD 2867

Query: 220  TVYYKLAK 227
            + +Y+ A+
Sbjct: 2868 SPFYQCAE 2875


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 53/188 (28%), Positives = 82/188 (43%), Gaps = 24/188 (12%)

Query: 60   RERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPG------ 113
            ++R +E++K    KS+K+K +        KE KK  +    C T  +   F  G      
Sbjct: 2709 QKRKREEEKDSSSKSKKKKMISTTS----KETKKDTKLYCICKTPYDESKFYIGCDRCQN 2764

Query: 114  ---------KKVEVEPPPDRPVRACR-TQPAENESTPIQQL----LEHFLRQLQRKDPHG 159
                      + E E   +     C+ T+ A    TP+ +     L+  LR LQ      
Sbjct: 2765 WYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAW 2824

Query: 160  FFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPD 219
             F  PV    AP Y  +IK PMD  TM++++    Y+ +TEF AD   + DN   YN  D
Sbjct: 2825 PFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSD 2884

Query: 220  TVYYKLAK 227
            + +Y+ A+
Sbjct: 2885 SPFYQCAE 2892


>gi|164419758 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 10/118 (8%)

Query: 121 PPDRPVRACRTQPAENESTPIQQLLEH---FLRQLQRKDPHGFFAFPV---TDAIAPG-- 172
           PP + +   + Q   ++   + + L+H    L++L  K  H  +A+P     DA A G  
Sbjct: 326 PPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKK-HAAYAWPFYKPVDASALGLH 384

Query: 173 -YSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKI 229
            Y  IIKHPMD  T+K K+   +Y+   EF AD +LM  N   YN PD     +A+K+
Sbjct: 385 DYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKL 442



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 10/103 (9%)

Query: 161 FAFPV---TDAIA---PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMT 214
           FA+P     DA+    P Y  IIK PMD GT+K ++  N Y + +E   DF  M  N   
Sbjct: 95  FAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYI 154

Query: 215 YNRPDTVYYKLAKKILHAGFKMMSKQAALLGNEDTAVEEPVPE 257
           YN+P      +A+ +     K+  ++ A +  E+  +   +P+
Sbjct: 155 YNKPTDDIVLMAQTL----EKIFLQKVASMPQEEQELVVTIPK 193



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 29/141 (20%), Positives = 55/141 (39%), Gaps = 28/141 (19%)

Query: 16  YEDYADKPLEK---PLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKK 72
           Y    D+PLE    P+   +  G ++ +  S S   SS      + E +   E++++ + 
Sbjct: 450 YAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESES 509

Query: 73  KSEKEKH-------------------------LDDEERRKRKEEKKRKREREHCDTEGEA 107
              +E+                          +   +R++ K+EKK+KR+ E       A
Sbjct: 510 SDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGA 569

Query: 108 DDFDPGKKVEVEPPPDRPVRA 128
           D+ D G +    P P +  +A
Sbjct: 570 DEDDKGPRAPRPPQPKKSKKA 590


>gi|4826806 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 10/118 (8%)

Query: 121 PPDRPVRACRTQPAENESTPIQQLLEH---FLRQLQRKDPHGFFAFPV---TDAIAPG-- 172
           PP + +   + Q   ++   + + L+H    L++L  K  H  +A+P     DA A G  
Sbjct: 326 PPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKK-HAAYAWPFYKPVDASALGLH 384

Query: 173 -YSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKI 229
            Y  IIKHPMD  T+K K+   +Y+   EF AD +LM  N   YN PD     +A+K+
Sbjct: 385 DYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKL 442



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 10/103 (9%)

Query: 161 FAFPV---TDAIA---PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMT 214
           FA+P     DA+    P Y  IIK PMD GT+K ++  N Y + +E   DF  M  N   
Sbjct: 95  FAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYI 154

Query: 215 YNRPDTVYYKLAKKILHAGFKMMSKQAALLGNEDTAVEEPVPE 257
           YN+P      +A+ +     K+  ++ A +  E+  +   +P+
Sbjct: 155 YNKPTDDIVLMAQTL----EKIFLQKVASMPQEEQELVVTIPK 193



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 29/141 (20%), Positives = 55/141 (39%), Gaps = 28/141 (19%)

Query: 16  YEDYADKPLEK---PLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKK 72
           Y    D+PLE    P+   +  G ++ +  S S   SS      + E +   E++++ + 
Sbjct: 450 YAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESES 509

Query: 73  KSEKEKH-------------------------LDDEERRKRKEEKKRKREREHCDTEGEA 107
              +E+                          +   +R++ K+EKK+KR+ E       A
Sbjct: 510 SDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGA 569

Query: 108 DDFDPGKKVEVEPPPDRPVRA 128
           D+ D G +    P P +  +A
Sbjct: 570 DEDDKGPRAPRPPQPKKSKKA 590


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 13/171 (7%)

Query: 71   KKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPPPDRPVRACR 130
            + K E    + +E+ +   + K+     E      E D+  P  KVEV+   +       
Sbjct: 974  ESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTA 1033

Query: 131  TQPAENESTP---------IQQLLEHFLRQLQRKDPHGF-FAFPVTDAIA--PGYSMIIK 178
            +Q + + S P         ++Q L   L  L R+DP    F  PV   +   P Y  I+K
Sbjct: 1034 SQ-STSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK 1092

Query: 179  HPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKI 229
            +PMD  T+K K+   +Y+   ++  D  LM +NA  YNR  +  YK   K+
Sbjct: 1093 NPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKL 1143


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 13/171 (7%)

Query: 71   KKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPPPDRPVRACR 130
            + K E    + +E+ +   + K+     E      E D+  P  KVEV+   +       
Sbjct: 1012 ESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTA 1071

Query: 131  TQPAENESTP---------IQQLLEHFLRQLQRKDPHGF-FAFPVTDAIA--PGYSMIIK 178
            +Q + + S P         ++Q L   L  L R+DP    F  PV   +   P Y  I+K
Sbjct: 1072 SQ-STSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK 1130

Query: 179  HPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKI 229
            +PMD  T+K K+   +Y+   ++  D  LM +NA  YNR  +  YK   K+
Sbjct: 1131 NPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKL 1181


>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform F [Homo sapiens]
          Length = 1613

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 59/284 (20%), Positives = 116/284 (40%), Gaps = 57/284 (20%)

Query: 2    GKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERE 61
            G +H+K          DY+D   EK     ++ G  E  E                 E  
Sbjct: 1337 GSRHRKEV--------DYSDSLTEKQWLKAIEEGTLEEIE-----------------EEV 1371

Query: 62   RHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPP 121
            R K+  +K+K+ S+          R R ++ + K++++            P +K+   PP
Sbjct: 1372 RQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKR--------GRPPAEKLSPNPP 1423

Query: 122  P-DRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP 180
               + ++       + + +  +QL E F++   RK+              P Y  +I+ P
Sbjct: 1424 NLTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRKE-------------LPEYYELIRKP 1470

Query: 181  MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYK---LAKKILHAGFKMM 237
            +DF  +K++I  ++Y+S+ + + D  L+C NA T+N   ++ Y+   + + +  +  + +
Sbjct: 1471 VDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKI 1530

Query: 238  SKQAALLGNEDTAVEEPVPE-------VVPVQVETAKKSKKPSR 274
             K+    G E    EE   E        V V+++  +K K   R
Sbjct: 1531 EKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDR 1574


>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform E [Homo sapiens]
          Length = 1614

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 60/285 (21%), Positives = 115/285 (40%), Gaps = 58/285 (20%)

Query: 2    GKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERE 61
            G +H+K          DY+D   EK     ++ G  E  E                 E  
Sbjct: 1337 GSRHRKEV--------DYSDSLTEKQWLKAIEEGTLEEIE-----------------EEV 1371

Query: 62   RHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPP 121
            R K+  +K+K+ S+          R R ++ + K++++            P +K+   PP
Sbjct: 1372 RQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKR--------GRPPAEKLSPNPP 1423

Query: 122  --PDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKH 179
                +  +         +S+  +QL E F++   RK+              P Y  +I+ 
Sbjct: 1424 NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKE-------------LPEYYELIRK 1470

Query: 180  PMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYK---LAKKILHAGFKM 236
            P+DF  +K++I  ++Y+S+ + + D  L+C NA T+N   ++ Y+   + + +  +  + 
Sbjct: 1471 PVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQK 1530

Query: 237  MSKQAALLGNEDTAVEEPVPE-------VVPVQVETAKKSKKPSR 274
            + K+    G E    EE   E        V V+++  +K K   R
Sbjct: 1531 IEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDR 1575


>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 60/285 (21%), Positives = 115/285 (40%), Gaps = 58/285 (20%)

Query: 2    GKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERE 61
            G +H+K          DY+D   EK     ++ G  E  E                 E  
Sbjct: 1370 GSRHRKEV--------DYSDSLTEKQWLKAIEEGTLEEIE-----------------EEV 1404

Query: 62   RHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPP 121
            R K+  +K+K+ S+          R R ++ + K++++            P +K+   PP
Sbjct: 1405 RQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKR--------GRPPAEKLSPNPP 1456

Query: 122  --PDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKH 179
                +  +         +S+  +QL E F++   RK+              P Y  +I+ 
Sbjct: 1457 NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKE-------------LPEYYELIRK 1503

Query: 180  PMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYK---LAKKILHAGFKM 236
            P+DF  +K++I  ++Y+S+ + + D  L+C NA T+N   ++ Y+   + + +  +  + 
Sbjct: 1504 PVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQK 1563

Query: 237  MSKQAALLGNEDTAVEEPVPE-------VVPVQVETAKKSKKPSR 274
            + K+    G E    EE   E        V V+++  +K K   R
Sbjct: 1564 IEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDR 1608


>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 60/285 (21%), Positives = 115/285 (40%), Gaps = 58/285 (20%)

Query: 2    GKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERE 61
            G +H+K          DY+D   EK     ++ G  E  E                 E  
Sbjct: 1370 GSRHRKEV--------DYSDSLTEKQWLKAIEEGTLEEIE-----------------EEV 1404

Query: 62   RHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPP 121
            R K+  +K+K+ S+          R R ++ + K++++            P +K+   PP
Sbjct: 1405 RQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKR--------GRPPAEKLSPNPP 1456

Query: 122  --PDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKH 179
                +  +         +S+  +QL E F++   RK+              P Y  +I+ 
Sbjct: 1457 NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKE-------------LPEYYELIRK 1503

Query: 180  PMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYK---LAKKILHAGFKM 236
            P+DF  +K++I  ++Y+S+ + + D  L+C NA T+N   ++ Y+   + + +  +  + 
Sbjct: 1504 PVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQK 1563

Query: 237  MSKQAALLGNEDTAVEEPVPE-------VVPVQVETAKKSKKPSR 274
            + K+    G E    EE   E        V V+++  +K K   R
Sbjct: 1564 IEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDR 1608


>gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens]
          Length = 757

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 30/66 (45%), Positives = 37/66 (56%)

Query: 161 FAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDT 220
           F  PVTD IAPGY  I++ PMD  T+K  I     +S  EF+ D  LM  NA+ YN  D 
Sbjct: 626 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDH 685

Query: 221 VYYKLA 226
             Y +A
Sbjct: 686 DVYHMA 691


>gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens]
          Length = 1235

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 30/66 (45%), Positives = 37/66 (56%)

Query: 161 FAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDT 220
           F  PVTD IAPGY  I++ PMD  T+K  I     +S  EF+ D  LM  NA+ YN  D 
Sbjct: 732 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDH 791

Query: 221 VYYKLA 226
             Y +A
Sbjct: 792 DVYHMA 797



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 23/66 (34%), Positives = 36/66 (54%)

Query: 161  FAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDT 220
            F  PV++  APGY  ++K PMD  ++K  +     +++ +F  D  LM  NA+ YN  D 
Sbjct: 1128 FLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDH 1187

Query: 221  VYYKLA 226
              Y +A
Sbjct: 1188 HVYHMA 1193


>gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens]
          Length = 951

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 30/66 (45%), Positives = 37/66 (56%)

Query: 161 FAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDT 220
           F  PVTD IAPGY  I++ PMD  T+K  I     +S  EF+ D  LM  NA+ YN  D 
Sbjct: 805 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDH 864

Query: 221 VYYKLA 226
             Y +A
Sbjct: 865 DVYHMA 870


>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform A [Homo sapiens]
          Length = 1679

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 59/294 (20%), Positives = 124/294 (42%), Gaps = 44/294 (14%)

Query: 2    GKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGS---------GHDSSYY 52
            G +H+K          DY+D   EK  + + K+ G ++ + + S         G      
Sbjct: 1370 GSRHRKEV--------DYSDSLTEK--QWLKKITGKDIHDTASSVARGLQFQRGLQFCTR 1419

Query: 53   DDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDP 112
              ++  E    + +++ ++KKS +++  D +          R R+++    + +     P
Sbjct: 1420 ASKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPP 1479

Query: 113  GKKVEVEPP--PDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIA 170
             +K+   PP    +  +         +S+  +QL E F++   RK+              
Sbjct: 1480 AEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKE-------------L 1526

Query: 171  PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYK---LAK 227
            P Y  +I+ P+DF  +K++I  ++Y+S+ + + D  L+C NA T+N   ++ Y+   + +
Sbjct: 1527 PEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQ 1586

Query: 228  KILHAGFKMMSKQAALLGNEDTAVEEPVPE-------VVPVQVETAKKSKKPSR 274
             +  +  + + K+    G E    EE   E        V V+++  +K K   R
Sbjct: 1587 SVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDR 1640


>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform C [Homo sapiens]
          Length = 1617

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 63/273 (23%), Positives = 119/273 (43%), Gaps = 48/273 (17%)

Query: 37   SEVTELSGSGHDSSYYDDRSDHERERH-----KEKKKKKKKKSEKEKHLDD--EERRKRK 89
            +EV  L+    +   +   S H +E        EK+  K  K+ +E  L++  EE R++K
Sbjct: 1319 AEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKTLKAIEEGTLEEIEEEVRQKK 1378

Query: 90   EEKKRKREREHCDT-------EGEADDFDPGKKVEVEPPPDR--PVRACRTQPAEN---- 136
              +KRKR+ +   +         + DD    +K    PP ++  P     T+  +     
Sbjct: 1379 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA 1438

Query: 137  -----ESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIV 191
                 +S+  +QL E F++   RK+              P Y  +I+ P+DF  +K++I 
Sbjct: 1439 VIKYKDSSSGRQLSEVFIQLPSRKE-------------LPEYYELIRKPVDFKKIKERIR 1485

Query: 192  ANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYK---LAKKILHAGFKMMSKQAALLGNED 248
             ++Y+S+ + + D  L+C NA T+N   ++ Y+   + + +  +  + + K+    G E 
Sbjct: 1486 NHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEES 1545

Query: 249  TAVEEPVPE-------VVPVQVETAKKSKKPSR 274
               EE   E        V V+++  +K K   R
Sbjct: 1546 EEEEEGEEEGSESESRSVKVKIKLGRKEKAQDR 1578


>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
            sapiens]
          Length = 1905

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 29/75 (38%), Positives = 42/75 (56%)

Query: 146  EHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADF 205
            E  L +++  D    F  PV   +  GY  IIK+PMDF TM+++++   Y S  EF AD 
Sbjct: 1803 EIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADA 1862

Query: 206  KLMCDNAMTYNRPDT 220
             L+ DN  T+N  D+
Sbjct: 1863 LLVFDNCQTFNEDDS 1877



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 27/95 (28%), Positives = 50/95 (52%), Gaps = 2/95 (2%)

Query: 6   KKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEV-TELSGSGHDSSYYDDRSDHERERHK 64
           KK +A+   + ED A K  +   K+  KV   E  T + G   +    + +S  ++E  K
Sbjct: 694 KKLEAQETLNEEDKA-KIAKSKKKMRQKVQRGECQTTIQGQARNKRKQETKSLKQKEAKK 752

Query: 65  EKKKKKKKKSEKEKHLDDEERRKRKEEKKRKRERE 99
           + K +K+K   K++ L ++ +R++KE+ K K + E
Sbjct: 753 KSKAEKEKGKTKQEKLKEKVKREKKEKVKMKEKEE 787


>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform D [Homo sapiens]
          Length = 1616

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 62/284 (21%), Positives = 116/284 (40%), Gaps = 54/284 (19%)

Query: 2    GKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERE 61
            G +H+K          DY+D   EK     LK     + E +    +      +S  +R+
Sbjct: 1337 GSRHRKEV--------DYSDSLTEKQWLKTLKA----IEEGTLEEIEEEVRQKKSSRKRK 1384

Query: 62   RHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPP 121
            R  +        S + +  DDE     K++KKR R               P +K+   PP
Sbjct: 1385 RDSDAGSSTPTTSTRSRDKDDES----KKQKKRGRP--------------PAEKLSPNPP 1426

Query: 122  P-DRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP 180
               + ++       + + +  +QL E F++   RK+              P Y  +I+ P
Sbjct: 1427 NLTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRKE-------------LPEYYELIRKP 1473

Query: 181  MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYK---LAKKILHAGFKMM 237
            +DF  +K++I  ++Y+S+ + + D  L+C NA T+N   ++ Y+   + + +  +  + +
Sbjct: 1474 VDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKI 1533

Query: 238  SKQAALLGNEDTAVEEPVPE-------VVPVQVETAKKSKKPSR 274
             K+    G E    EE   E        V V+++  +K K   R
Sbjct: 1534 EKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDR 1577


>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
            sapiens]
          Length = 1483

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 58/193 (30%), Positives = 81/193 (41%), Gaps = 27/193 (13%)

Query: 36   GSEVTELSGSGHDSSYYDDRSDHERERHKEKKKK----------KKKKSEKEKH--LDDE 83
            G   TE S S  DS   DD SD E E  +E++++          + +K+ + KH  +   
Sbjct: 1242 GRNYTEESAS-EDSE--DDESDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVIPPA 1298

Query: 84   ERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPPPDRPVRACRTQPAENESTPIQQ 143
             R  R+  KK    R         DD       EV+    +  R+ R Q  E       Q
Sbjct: 1299 ARSGRRPGKKPHSTRRSQPKAPPVDD------AEVDELVLQTKRSSRRQSLE------LQ 1346

Query: 144  LLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKA 203
              E  L ++ +      F  PVT   A  Y  +I HPMDF T+++K     Y+SV EF  
Sbjct: 1347 KCEEILHKIVKYRFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLT 1406

Query: 204  DFKLMCDNAMTYN 216
            D K +  NA  YN
Sbjct: 1407 DMKQVFTNAEVYN 1419



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 15/46 (32%), Positives = 30/46 (65%), Gaps = 2/46 (4%)

Query: 56  SDHERERHKEKKKKKKKK--SEKEKHLDDEERRKRKEEKKRKRERE 99
           S+ +R+ + +KK+++ KK   EK K   ++E  +R E++KR  ++E
Sbjct: 539 SEEQRKEYLKKKREELKKKLKEKAKERREKEMLERLEKQKRYEDQE 584


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.129    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,773,793
Number of Sequences: 37866
Number of extensions: 1241329
Number of successful extensions: 24886
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 591
Number of HSP's successfully gapped in prelim test: 316
Number of HSP's that attempted gapping in prelim test: 9290
Number of HSP's gapped (non-prelim): 8544
length of query: 597
length of database: 18,247,518
effective HSP length: 108
effective length of query: 489
effective length of database: 14,157,990
effective search space: 6923257110
effective search space used: 6923257110
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.