BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens] (597 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens] 1198 0.0 gi|242247075 bromodomain containing 9 isoform 2 [Homo sapiens] 882 0.0 gi|41350212 bromodomain containing 7 [Homo sapiens] 349 5e-96 gi|11321642 bromodomain containing protein 1 [Homo sapiens] 97 3e-20 gi|239753965 PREDICTED: zinc finger, DHHC-type containing 11B [H... 86 1e-16 gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi... 77 5e-14 gi|51173722 bromodomain and PHD finger-containing protein 1 isof... 75 2e-13 gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 69 9e-12 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 69 9e-12 gi|51173720 bromodomain and PHD finger-containing protein 1 isof... 69 2e-11 gi|50345997 E1A binding protein p300 [Homo sapiens] 67 4e-11 gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 64 4e-10 gi|38788260 bromodomain PHD finger transcription factor isoform ... 62 1e-09 gi|38788274 bromodomain PHD finger transcription factor isoform ... 62 1e-09 gi|164419758 bromodomain containing 2 [Homo sapiens] 60 4e-09 gi|4826806 bromodomain containing 2 [Homo sapiens] 60 4e-09 gi|119943102 CREB binding protein isoform b [Homo sapiens] 60 7e-09 gi|119943104 CREB binding protein isoform a [Homo sapiens] 60 7e-09 gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 59 1e-08 gi|192807318 SWI/SNF-related matrix-associated actin-dependent r... 59 1e-08 gi|192807312 SWI/SNF-related matrix-associated actin-dependent r... 59 1e-08 gi|21071056 SWI/SNF-related matrix-associated actin-dependent re... 59 1e-08 gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens] 59 1e-08 gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens] 59 1e-08 gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens] 59 1e-08 gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 59 1e-08 gi|192807314 SWI/SNF-related matrix-associated actin-dependent r... 59 1e-08 gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 59 1e-08 gi|192807316 SWI/SNF-related matrix-associated actin-dependent r... 59 2e-08 gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 59 2e-08 >gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens] Length = 597 Score = 1198 bits (3100), Expect = 0.0 Identities = 597/597 (100%), Positives = 597/597 (100%) Query: 1 MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHER 60 MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHER Sbjct: 1 MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHER 60 Query: 61 ERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEP 120 ERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEP Sbjct: 61 ERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEP 120 Query: 121 PPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP 180 PPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP Sbjct: 121 PPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP 180 Query: 181 MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQ 240 MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQ Sbjct: 181 MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQ 240 Query: 241 AALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVL 300 AALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVL Sbjct: 241 AALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVL 300 Query: 301 ALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLS 360 ALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLS Sbjct: 301 ALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLS 360 Query: 361 SKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQ 420 SKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQ Sbjct: 361 SKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQ 420 Query: 421 CALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLG 480 CALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLG Sbjct: 421 CALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLG 480 Query: 481 DSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAE 540 DSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAE Sbjct: 481 DSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAE 540 Query: 541 RGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT 597 RGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT Sbjct: 541 RGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT 597 >gi|242247075 bromodomain containing 9 isoform 2 [Homo sapiens] Length = 544 Score = 882 bits (2279), Expect = 0.0 Identities = 461/547 (84%), Positives = 481/547 (87%), Gaps = 21/547 (3%) Query: 61 ERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDP---GKKVE 117 ER +K+K+++++S + + + RK E+KR+ E T + G++ Sbjct: 9 ERGTKKRKRRRRRSPRRRSI--WTMRKEGSERKRRSGSERGSTVTRRERLTTLILGRRWR 66 Query: 118 VEPPP-DRPVRACRTQPAENESTPIQQLLEHFLRQLQR------KDPHGFFAFPVTDAIA 170 P + RA +QP ++ H +DPHGFFAFPVTDAIA Sbjct: 67 WSRPQIGQSERAGHSQP---------KMRAHLFSNSWNTSSASFRDPHGFFAFPVTDAIA 117 Query: 171 PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKIL 230 PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKIL Sbjct: 118 PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKIL 177 Query: 231 HAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSL 290 HAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSL Sbjct: 178 HAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSL 237 Query: 291 TDSTAEEHVLALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEE 350 TDSTAEEHVLALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEE Sbjct: 238 TDSTAEEHVLALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEE 297 Query: 351 THPVDLSSLSSKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLY 410 THPVDLSSLSSKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLY Sbjct: 298 THPVDLSSLSSKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLY 357 Query: 411 SAYGDETGVQCALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPP 470 SAYGDETGVQCALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPP Sbjct: 358 SAYGDETGVQCALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPP 417 Query: 471 DEAKVGDTLGDSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKL 530 DEAKVGDTLGDSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKL Sbjct: 418 DEAKVGDTLGDSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKL 477 Query: 531 LQDLHEAQAERGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPE 590 LQDLHEAQAERGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPE Sbjct: 478 LQDLHEAQAERGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPE 537 Query: 591 PAASAKT 597 PAASAKT Sbjct: 538 PAASAKT 544 >gi|41350212 bromodomain containing 7 [Homo sapiens] Length = 651 Score = 349 bits (895), Expect = 5e-96 Identities = 215/606 (35%), Positives = 340/606 (56%), Gaps = 66/606 (10%) Query: 1 MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELS--GSGHDSSYYDDRSDH 58 MGKKHKKHK++ + YE+Y +EKPLKLVLKVGG+EVTELS SGHDSS ++D++DH Sbjct: 1 MGKKHKKHKSD-KHLYEEY----VEKPLKLVLKVGGNEVTELSTGSSGHDSSLFEDKNDH 55 Query: 59 ERERHKEKKKKKKKKSEKEKHLDDEERRKRK-EEKKRKREREHCDTEGEADDFDPGKKVE 117 ++ HK++K+KK+KK EK+ +++ R++R+ +E K+KR+R+ + E E D V Sbjct: 56 DK--HKDRKRKKRKKGEKQIPGEEKGRKRRRVKEDKKKRDRDRVENEAEKD-LQCHAPVR 112 Query: 118 VEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMII 177 ++ PP++P+ + + E E TP+Q+ L +RQLQRKDP FF+FPVTD IAPGYSMII Sbjct: 113 LDLPPEKPLTSSLAKQEEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMII 172 Query: 178 KHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMM 237 KHPMDF TMK+KI N+Y+S+ E K +FKLMC NAM YN+P+T+YYK AKK+LH+G K++ Sbjct: 173 KHPMDFSTMKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKIL 232 Query: 238 SKQ--------------------------AALLGNEDTAVEEPVPEVVPVQVETAKKSKK 271 S++ + G + + + + K K Sbjct: 233 SQERIQSLKQSIDFMADLQKTRKQKDGTDTSQSGEDGGCWQREREDSGDAEAHAFKSPSK 292 Query: 272 PSREVISCMFEPEGNACSLTDSTAEEHVLALVEHAADEARDRINRFLPGGKMGYLKRNGD 331 +++ M E + + +L E ++ E+ ++ R L + + +R D Sbjct: 293 ENKKKDKDMLEDKFKSNNL------EREQEQLDRIVKESGGKLTRRLVNSQCEFERRKPD 346 Query: 332 GSLLYSVVNTAEPDADEEETHPVDLSSLSSKLLPGFTTL-GFKDERRNKVT---FLS-SA 386 G+ +++ +P E PV L + +L G TL GFK+++RNKVT +L+ Sbjct: 347 GTTTLGLLHPVDPIVGEPGYCPVRLGMTTGRLQSGVNTLQGFKEDKRNKVTPVLYLNYGP 406 Query: 387 TTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQCALSLQEFVKDAGSYSKKVVDDLLDQ 446 ++ + +S F ++ D+ +L+YS YG+++ + S+ EF+ Y + D LLD Sbjct: 407 YSSYAPHYDSTFANISKDDSDLIYSTYGEDSDLPSDFSIHEFLATCQDYPYVMADSLLDV 466 Query: 447 ITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLGDSSSSVLEFMSMK-------SYPDVS 499 +T G HSRTL +++ P DE G T ++ +E ++ S D Sbjct: 467 LTKGGHSRTLQEMEM-----SLPEDE---GHTRTLDTAKEMEITEVEPPGRLDSSTQDRL 518 Query: 500 VDISMLSSLGKVKKELDPDDSHL---NLDETTKLLQDLHEAQAERGGSRPSSNLSSLSNA 556 + + +++ G + D +++ + LDETT+LL++L EAQ ER +RP N+ L Sbjct: 519 IALKAVTNFGVPVEVFDSEEAEIFQKKLDETTRLLRELQEAQNERLSTRPPPNMICLLGP 578 Query: 557 SERDQH 562 S R+ H Sbjct: 579 SYREMH 584 >gi|11321642 bromodomain containing protein 1 [Homo sapiens] Length = 1058 Score = 97.4 bits (241), Expect = 3e-20 Identities = 67/185 (36%), Positives = 90/185 (48%), Gaps = 23/185 (12%) Query: 49 SSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEAD 108 SS RS +RE +E K K+K ++ D ER + E RKRE+ + Sbjct: 498 SSLQSQRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIELLRKREKLKRE------ 551 Query: 109 DFDPGKKVEVEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDA 168 +V+VE E TP+ LL L QLQ KDP FA PV+ Sbjct: 552 ------QVKVEQVA-----------MELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSLK 594 Query: 169 IAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKK 228 P Y IKHPMDF TM+ ++ A YK++ EF+ DF L+ DN M YN DTV+Y+ A + Sbjct: 595 EVPDYLDHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVR 654 Query: 229 ILHAG 233 + G Sbjct: 655 LRDQG 659 >gi|239753965 PREDICTED: zinc finger, DHHC-type containing 11B [Homo sapiens] Length = 573 Score = 85.9 bits (211), Expect = 1e-16 Identities = 42/49 (85%), Positives = 44/49 (89%) Query: 375 ERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQCAL 423 + R VTFLSSATT LSMQNNS FGDLKSDE+ELLYSAYGDETGVQCAL Sbjct: 7 DARAPVTFLSSATTTLSMQNNSAFGDLKSDELELLYSAYGDETGVQCAL 55 >gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapiens] Length = 1205 Score = 77.0 bits (188), Expect = 5e-14 Identities = 55/185 (29%), Positives = 85/185 (45%), Gaps = 23/185 (12%) Query: 49 SSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEAD 108 S R+ +RE+ ++ K++ +K D ER + E RKRE+ Sbjct: 525 SHLQSQRNAEQREQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKL--------- 575 Query: 109 DFDPGKKVEVEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDA 168 K+ +V+ + E E P LL L LQ KDP FA PV + Sbjct: 576 -----KREQVK---------VQQAAMELELMPFNVLLRTTLDLLQEKDPAHIFAEPVNLS 621 Query: 169 IAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKK 228 P Y I PMDF TM+ K+ ++ Y+++ EF+ DF L+ N M YN DT++++ A + Sbjct: 622 EVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYNAKDTIFHRAAVR 681 Query: 229 ILHAG 233 + G Sbjct: 682 LRDLG 686 >gi|51173722 bromodomain and PHD finger-containing protein 1 isoform 2 [Homo sapiens] Length = 1214 Score = 74.7 bits (182), Expect = 2e-13 Identities = 42/114 (36%), Positives = 59/114 (51%), Gaps = 3/114 (2%) Query: 135 ENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANE 194 E + TP LL L QLQ KD F+ PV + P Y IK PMDF TMK + A Sbjct: 627 EMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYR 686 Query: 195 YKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAG---FKMMSKQAALLG 245 Y + +F+ DF L+ N + YN DT++Y+ A ++ G + +QA +G Sbjct: 687 YLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMG 740 >gi|7657218 bromodomain-containing protein 4 isoform short [Homo sapiens] Length = 722 Score = 69.3 bits (168), Expect = 9e-12 Identities = 63/193 (32%), Positives = 89/193 (46%), Gaps = 18/193 (9%) Query: 121 PPDRPVRACRTQPAENESTPIQQLLE---HFLRQLQRKDPHGFFAFPV---TDAIAPG-- 172 PP + V + PA +S+ + + L+ L+++ K H +A+P D A G Sbjct: 330 PPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKK-HAAYAWPFYKPVDVEALGLH 388 Query: 173 -YSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILH 231 Y IIKHPMD T+K K+ A EY+ EF AD +LM N YN PD +A+K L Sbjct: 389 DYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARK-LQ 447 Query: 232 AGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLT 291 F+M + A + +E EEPV V V K P S + ++ S T Sbjct: 448 DVFEM---RFAKMPDEP---EEPVVAVSSPAVPPPTKVVAPPSSSDSSS-DSSSDSDSST 500 Query: 292 DSTAEEHVLALVE 304 D + EE L E Sbjct: 501 DDSEEERAQRLAE 513 Score = 50.8 bits (120), Expect = 3e-06 Identities = 50/179 (27%), Positives = 77/179 (43%), Gaps = 22/179 (12%) Query: 112 PGKKVEVEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIA- 170 P PPP P + +P + ++ +Q LL L+ L + F PV DA+ Sbjct: 37 PANAASTNPPP--PETSNPNKP-KRQTNQLQYLLRVVLKTLWKHQFAWPFQQPV-DAVKL 92 Query: 171 --PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRP--DTVYY--K 224 P Y IIK PMD GT+K ++ N Y + E DF M N YN+P D V Sbjct: 93 NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEA 152 Query: 225 LAKKILHAGFKMMSKQAALL---------GNEDTAVEEPVPEVVP--VQVETAKKSKKP 272 L K L ++ +++ ++ G ++T +P VP Q T +++ P Sbjct: 153 LEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTP 211 Score = 38.9 bits (89), Expect = 0.014 Identities = 31/122 (25%), Positives = 58/122 (47%), Gaps = 10/122 (8%) Query: 27 PLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERR 86 P K+V S+ + S S DSS DD + +R E +++ K E+ L ++ Sbjct: 476 PTKVVAPPSSSDSSSDSSSDSDSST-DDSEEERAQRLAELQEQLKAVHEQLAALSQPQQN 534 Query: 87 KRKEEKKRKREREHCDTEGEADDFDPGKKVEV-EPPPDRPVR-------ACRTQPAENES 138 K K+++K K+E++ + ++ + KK + EPPP + + + +PA +S Sbjct: 535 KPKKKEKDKKEKKK-EKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKS 593 Query: 139 TP 140 P Sbjct: 594 KP 595 Score = 33.5 bits (75), Expect = 0.57 Identities = 20/87 (22%), Positives = 43/87 (49%), Gaps = 2/87 (2%) Query: 37 SEVTELSGSGHDSSYYDDRSDHERERHKEK-KKKKKKKSEKEKHLDDEERRKRKEEKKRK 95 +E+ E + H+ + + + KEK KK+KKK+ K K +E ++ + +E K Sbjct: 512 AELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPK 571 Query: 96 REREHCDTEGEADDFDPGKKVEVEPPP 122 + +++ + +P ++ +PPP Sbjct: 572 KTKKNNSSNSNVSKKEPA-PMKSKPPP 597 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 69.3 bits (168), Expect = 9e-12 Identities = 63/193 (32%), Positives = 89/193 (46%), Gaps = 18/193 (9%) Query: 121 PPDRPVRACRTQPAENESTPIQQLLE---HFLRQLQRKDPHGFFAFPV---TDAIAPG-- 172 PP + V + PA +S+ + + L+ L+++ K H +A+P D A G Sbjct: 330 PPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKK-HAAYAWPFYKPVDVEALGLH 388 Query: 173 -YSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILH 231 Y IIKHPMD T+K K+ A EY+ EF AD +LM N YN PD +A+K L Sbjct: 389 DYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARK-LQ 447 Query: 232 AGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLT 291 F+M + A + +E EEPV V V K P S + ++ S T Sbjct: 448 DVFEM---RFAKMPDEP---EEPVVAVSSPAVPPPTKVVAPPSSSDSSS-DSSSDSDSST 500 Query: 292 DSTAEEHVLALVE 304 D + EE L E Sbjct: 501 DDSEEERAQRLAE 513 Score = 50.8 bits (120), Expect = 3e-06 Identities = 50/179 (27%), Positives = 77/179 (43%), Gaps = 22/179 (12%) Query: 112 PGKKVEVEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIA- 170 P PPP P + +P + ++ +Q LL L+ L + F PV DA+ Sbjct: 37 PANAASTNPPP--PETSNPNKP-KRQTNQLQYLLRVVLKTLWKHQFAWPFQQPV-DAVKL 92 Query: 171 --PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRP--DTVYY--K 224 P Y IIK PMD GT+K ++ N Y + E DF M N YN+P D V Sbjct: 93 NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEA 152 Query: 225 LAKKILHAGFKMMSKQAALL---------GNEDTAVEEPVPEVVP--VQVETAKKSKKP 272 L K L ++ +++ ++ G ++T +P VP Q T +++ P Sbjct: 153 LEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTP 211 Score = 38.9 bits (89), Expect = 0.014 Identities = 31/122 (25%), Positives = 58/122 (47%), Gaps = 10/122 (8%) Query: 27 PLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERR 86 P K+V S+ + S S DSS DD + +R E +++ K E+ L ++ Sbjct: 476 PTKVVAPPSSSDSSSDSSSDSDSST-DDSEEERAQRLAELQEQLKAVHEQLAALSQPQQN 534 Query: 87 KRKEEKKRKREREHCDTEGEADDFDPGKKVEV-EPPPDRPVR-------ACRTQPAENES 138 K K+++K K+E++ + ++ + KK + EPPP + + + +PA +S Sbjct: 535 KPKKKEKDKKEKKK-EKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKS 593 Query: 139 TP 140 P Sbjct: 594 KP 595 Score = 33.5 bits (75), Expect = 0.57 Identities = 20/87 (22%), Positives = 43/87 (49%), Gaps = 2/87 (2%) Query: 37 SEVTELSGSGHDSSYYDDRSDHERERHKEK-KKKKKKKSEKEKHLDDEERRKRKEEKKRK 95 +E+ E + H+ + + + KEK KK+KKK+ K K +E ++ + +E K Sbjct: 512 AELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPK 571 Query: 96 REREHCDTEGEADDFDPGKKVEVEPPP 122 + +++ + +P ++ +PPP Sbjct: 572 KTKKNNSSNSNVSKKEPA-PMKSKPPP 597 >gi|51173720 bromodomain and PHD finger-containing protein 1 isoform 1 [Homo sapiens] Length = 1220 Score = 68.6 bits (166), Expect = 2e-11 Identities = 43/121 (35%), Positives = 60/121 (49%), Gaps = 11/121 (9%) Query: 135 ENESTPIQQLLEHFLRQLQRKDPHGFFAFPVT-------DAIAPGYSMIIKHPMDFGTMK 187 E + TP LL L QLQ KD F+ PV D + P Y IK PMDF TMK Sbjct: 627 EMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVTELDEV-PDYLDHIKKPMDFFTMK 685 Query: 188 DKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAG---FKMMSKQAALL 244 + A Y + +F+ DF L+ N + YN DT++Y+ A ++ G + +QA + Sbjct: 686 QNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKM 745 Query: 245 G 245 G Sbjct: 746 G 746 >gi|50345997 E1A binding protein p300 [Homo sapiens] Length = 2414 Score = 67.4 bits (163), Expect = 4e-11 Identities = 51/177 (28%), Positives = 81/177 (45%), Gaps = 12/177 (6%) Query: 65 EKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEG-EADDFDPGKKVEVEPPPD 123 EK+ ++ K E + +D E + E + + E C E E ++ K E++ D Sbjct: 969 EKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEED 1028 Query: 124 RP-VRACRTQPAENESTP-------IQQLLEHFLRQLQRKDPHGF-FAFPVTDAIA--PG 172 +P A ++ PA +S ++Q L L L R+DP F PV + P Sbjct: 1029 QPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPD 1088 Query: 173 YSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKI 229 Y I+K PMD T+K K+ +Y+ ++ D LM +NA YNR + YK K+ Sbjct: 1089 YFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKL 1145 >gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo sapiens] Length = 2168 Score = 63.9 bits (154), Expect = 4e-10 Identities = 44/165 (26%), Positives = 72/165 (43%), Gaps = 26/165 (15%) Query: 64 KEKKKKKKKKSEKEKHLDDEE--------RRKRKEEKKRKREREHCDTEGEADDFDPGKK 115 K + KK KK +DE+ +R K+ KKRK E + + F KK Sbjct: 1998 KTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKMEENTSINLSKQESFTSVKK 2057 Query: 116 VEVEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSM 175 P ++S + L L +++ + F PV + PGY Sbjct: 2058 -----------------PKRDDSKDLA-LCSMILTEMETHEDAWPFLLPVNLKLVPGYKK 2099 Query: 176 IIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDT 220 +IK PMDF T+++K+ + +Y ++ F D +L+ DN T+N D+ Sbjct: 2100 VIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDS 2144 Score = 32.7 bits (73), Expect = 0.97 Identities = 20/75 (26%), Positives = 41/75 (54%), Gaps = 8/75 (10%) Query: 59 ERERHKE-----KKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPG 113 ERER ++ K + +KK+E+++ L E+R +++ K+RK E+ + E + P Sbjct: 1004 ERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPN 1063 Query: 114 KKV---EVEPPPDRP 125 + + + +P P+ P Sbjct: 1064 EDMCLADQKPLPELP 1078 Score = 30.0 bits (66), Expect = 6.3 Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 10/46 (21%) Query: 65 EKKKKKKKKSEKEKHLDDEERRKRKE----------EKKRKREREH 100 E KKKKK+++ K L+ E+R K KE ++R+R R+H Sbjct: 966 EAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQH 1011 >gi|38788260 bromodomain PHD finger transcription factor isoform 2 [Homo sapiens] Length = 2903 Score = 62.4 bits (150), Expect = 1e-09 Identities = 53/188 (28%), Positives = 82/188 (43%), Gaps = 24/188 (12%) Query: 60 RERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPG------ 113 ++R +E++K KS+K+K + KE KK + C T + F G Sbjct: 2692 QKRKREEEKDSSSKSKKKKMISTTS----KETKKDTKLYCICKTPYDESKFYIGCDRCQN 2747 Query: 114 ---------KKVEVEPPPDRPVRACR-TQPAENESTPIQQL----LEHFLRQLQRKDPHG 159 + E E + C+ T+ A TP+ + L+ LR LQ Sbjct: 2748 WYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAW 2807 Query: 160 FFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPD 219 F PV AP Y +IK PMD TM++++ Y+ +TEF AD + DN YN D Sbjct: 2808 PFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSD 2867 Query: 220 TVYYKLAK 227 + +Y+ A+ Sbjct: 2868 SPFYQCAE 2875 >gi|38788274 bromodomain PHD finger transcription factor isoform 1 [Homo sapiens] Length = 2920 Score = 62.4 bits (150), Expect = 1e-09 Identities = 53/188 (28%), Positives = 82/188 (43%), Gaps = 24/188 (12%) Query: 60 RERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPG------ 113 ++R +E++K KS+K+K + KE KK + C T + F G Sbjct: 2709 QKRKREEEKDSSSKSKKKKMISTTS----KETKKDTKLYCICKTPYDESKFYIGCDRCQN 2764 Query: 114 ---------KKVEVEPPPDRPVRACR-TQPAENESTPIQQL----LEHFLRQLQRKDPHG 159 + E E + C+ T+ A TP+ + L+ LR LQ Sbjct: 2765 WYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAW 2824 Query: 160 FFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPD 219 F PV AP Y +IK PMD TM++++ Y+ +TEF AD + DN YN D Sbjct: 2825 PFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSD 2884 Query: 220 TVYYKLAK 227 + +Y+ A+ Sbjct: 2885 SPFYQCAE 2892 >gi|164419758 bromodomain containing 2 [Homo sapiens] Length = 801 Score = 60.5 bits (145), Expect = 4e-09 Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 10/118 (8%) Query: 121 PPDRPVRACRTQPAENESTPIQQLLEH---FLRQLQRKDPHGFFAFPV---TDAIAPG-- 172 PP + + + Q ++ + + L+H L++L K H +A+P DA A G Sbjct: 326 PPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKK-HAAYAWPFYKPVDASALGLH 384 Query: 173 -YSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKI 229 Y IIKHPMD T+K K+ +Y+ EF AD +LM N YN PD +A+K+ Sbjct: 385 DYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKL 442 Score = 46.6 bits (109), Expect = 7e-05 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 10/103 (9%) Query: 161 FAFPV---TDAIA---PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMT 214 FA+P DA+ P Y IIK PMD GT+K ++ N Y + +E DF M N Sbjct: 95 FAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYI 154 Query: 215 YNRPDTVYYKLAKKILHAGFKMMSKQAALLGNEDTAVEEPVPE 257 YN+P +A+ + K+ ++ A + E+ + +P+ Sbjct: 155 YNKPTDDIVLMAQTL----EKIFLQKVASMPQEEQELVVTIPK 193 Score = 38.1 bits (87), Expect = 0.023 Identities = 29/141 (20%), Positives = 55/141 (39%), Gaps = 28/141 (19%) Query: 16 YEDYADKPLEK---PLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKK 72 Y D+PLE P+ + G ++ + S S SS + E + E++++ + Sbjct: 450 YAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESES 509 Query: 73 KSEKEKH-------------------------LDDEERRKRKEEKKRKREREHCDTEGEA 107 +E+ + +R++ K+EKK+KR+ E A Sbjct: 510 SDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGA 569 Query: 108 DDFDPGKKVEVEPPPDRPVRA 128 D+ D G + P P + +A Sbjct: 570 DEDDKGPRAPRPPQPKKSKKA 590 >gi|4826806 bromodomain containing 2 [Homo sapiens] Length = 801 Score = 60.5 bits (145), Expect = 4e-09 Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 10/118 (8%) Query: 121 PPDRPVRACRTQPAENESTPIQQLLEH---FLRQLQRKDPHGFFAFPV---TDAIAPG-- 172 PP + + + Q ++ + + L+H L++L K H +A+P DA A G Sbjct: 326 PPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKK-HAAYAWPFYKPVDASALGLH 384 Query: 173 -YSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKI 229 Y IIKHPMD T+K K+ +Y+ EF AD +LM N YN PD +A+K+ Sbjct: 385 DYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKL 442 Score = 46.6 bits (109), Expect = 7e-05 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 10/103 (9%) Query: 161 FAFPV---TDAIA---PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMT 214 FA+P DA+ P Y IIK PMD GT+K ++ N Y + +E DF M N Sbjct: 95 FAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYI 154 Query: 215 YNRPDTVYYKLAKKILHAGFKMMSKQAALLGNEDTAVEEPVPE 257 YN+P +A+ + K+ ++ A + E+ + +P+ Sbjct: 155 YNKPTDDIVLMAQTL----EKIFLQKVASMPQEEQELVVTIPK 193 Score = 38.1 bits (87), Expect = 0.023 Identities = 29/141 (20%), Positives = 55/141 (39%), Gaps = 28/141 (19%) Query: 16 YEDYADKPLEK---PLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKK 72 Y D+PLE P+ + G ++ + S S SS + E + E++++ + Sbjct: 450 YAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESES 509 Query: 73 KSEKEKH-------------------------LDDEERRKRKEEKKRKREREHCDTEGEA 107 +E+ + +R++ K+EKK+KR+ E A Sbjct: 510 SDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGA 569 Query: 108 DDFDPGKKVEVEPPPDRPVRA 128 D+ D G + P P + +A Sbjct: 570 DEDDKGPRAPRPPQPKKSKKA 590 >gi|119943102 CREB binding protein isoform b [Homo sapiens] Length = 2404 Score = 59.7 bits (143), Expect = 7e-09 Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 13/171 (7%) Query: 71 KKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPPPDRPVRACR 130 + K E + +E+ + + K+ E E D+ P KVEV+ + Sbjct: 974 ESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTA 1033 Query: 131 TQPAENESTP---------IQQLLEHFLRQLQRKDPHGF-FAFPVTDAIA--PGYSMIIK 178 +Q + + S P ++Q L L L R+DP F PV + P Y I+K Sbjct: 1034 SQ-STSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK 1092 Query: 179 HPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKI 229 +PMD T+K K+ +Y+ ++ D LM +NA YNR + YK K+ Sbjct: 1093 NPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKL 1143 >gi|119943104 CREB binding protein isoform a [Homo sapiens] Length = 2442 Score = 59.7 bits (143), Expect = 7e-09 Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 13/171 (7%) Query: 71 KKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPPPDRPVRACR 130 + K E + +E+ + + K+ E E D+ P KVEV+ + Sbjct: 1012 ESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTA 1071 Query: 131 TQPAENESTP---------IQQLLEHFLRQLQRKDPHGF-FAFPVTDAIA--PGYSMIIK 178 +Q + + S P ++Q L L L R+DP F PV + P Y I+K Sbjct: 1072 SQ-STSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK 1130 Query: 179 HPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKI 229 +PMD T+K K+ +Y+ ++ D LM +NA YNR + YK K+ Sbjct: 1131 NPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKL 1181 >gi|192807320 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform F [Homo sapiens] Length = 1613 Score = 59.3 bits (142), Expect = 1e-08 Identities = 59/284 (20%), Positives = 116/284 (40%), Gaps = 57/284 (20%) Query: 2 GKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERE 61 G +H+K DY+D EK ++ G E E E Sbjct: 1337 GSRHRKEV--------DYSDSLTEKQWLKAIEEGTLEEIE-----------------EEV 1371 Query: 62 RHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPP 121 R K+ +K+K+ S+ R R ++ + K++++ P +K+ PP Sbjct: 1372 RQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKR--------GRPPAEKLSPNPP 1423 Query: 122 P-DRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP 180 + ++ + + + +QL E F++ RK+ P Y +I+ P Sbjct: 1424 NLTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRKE-------------LPEYYELIRKP 1470 Query: 181 MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYK---LAKKILHAGFKMM 237 +DF +K++I ++Y+S+ + + D L+C NA T+N ++ Y+ + + + + + + Sbjct: 1471 VDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKI 1530 Query: 238 SKQAALLGNEDTAVEEPVPE-------VVPVQVETAKKSKKPSR 274 K+ G E EE E V V+++ +K K R Sbjct: 1531 EKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDR 1574 >gi|192807318 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform E [Homo sapiens] Length = 1614 Score = 59.3 bits (142), Expect = 1e-08 Identities = 60/285 (21%), Positives = 115/285 (40%), Gaps = 58/285 (20%) Query: 2 GKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERE 61 G +H+K DY+D EK ++ G E E E Sbjct: 1337 GSRHRKEV--------DYSDSLTEKQWLKAIEEGTLEEIE-----------------EEV 1371 Query: 62 RHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPP 121 R K+ +K+K+ S+ R R ++ + K++++ P +K+ PP Sbjct: 1372 RQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKR--------GRPPAEKLSPNPP 1423 Query: 122 --PDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKH 179 + + +S+ +QL E F++ RK+ P Y +I+ Sbjct: 1424 NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKE-------------LPEYYELIRK 1470 Query: 180 PMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYK---LAKKILHAGFKM 236 P+DF +K++I ++Y+S+ + + D L+C NA T+N ++ Y+ + + + + + Sbjct: 1471 PVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQK 1530 Query: 237 MSKQAALLGNEDTAVEEPVPE-------VVPVQVETAKKSKKPSR 274 + K+ G E EE E V V+++ +K K R Sbjct: 1531 IEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDR 1575 >gi|192807312 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform B [Homo sapiens] Length = 1647 Score = 59.3 bits (142), Expect = 1e-08 Identities = 60/285 (21%), Positives = 115/285 (40%), Gaps = 58/285 (20%) Query: 2 GKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERE 61 G +H+K DY+D EK ++ G E E E Sbjct: 1370 GSRHRKEV--------DYSDSLTEKQWLKAIEEGTLEEIE-----------------EEV 1404 Query: 62 RHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPP 121 R K+ +K+K+ S+ R R ++ + K++++ P +K+ PP Sbjct: 1405 RQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKR--------GRPPAEKLSPNPP 1456 Query: 122 --PDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKH 179 + + +S+ +QL E F++ RK+ P Y +I+ Sbjct: 1457 NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKE-------------LPEYYELIRK 1503 Query: 180 PMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYK---LAKKILHAGFKM 236 P+DF +K++I ++Y+S+ + + D L+C NA T+N ++ Y+ + + + + + Sbjct: 1504 PVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQK 1563 Query: 237 MSKQAALLGNEDTAVEEPVPE-------VVPVQVETAKKSKKPSR 274 + K+ G E EE E V V+++ +K K R Sbjct: 1564 IEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDR 1608 >gi|21071056 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform B [Homo sapiens] Length = 1647 Score = 59.3 bits (142), Expect = 1e-08 Identities = 60/285 (21%), Positives = 115/285 (40%), Gaps = 58/285 (20%) Query: 2 GKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERE 61 G +H+K DY+D EK ++ G E E E Sbjct: 1370 GSRHRKEV--------DYSDSLTEKQWLKAIEEGTLEEIE-----------------EEV 1404 Query: 62 RHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPP 121 R K+ +K+K+ S+ R R ++ + K++++ P +K+ PP Sbjct: 1405 RQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKR--------GRPPAEKLSPNPP 1456 Query: 122 --PDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKH 179 + + +S+ +QL E F++ RK+ P Y +I+ Sbjct: 1457 NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKE-------------LPEYYELIRK 1503 Query: 180 PMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYK---LAKKILHAGFKM 236 P+DF +K++I ++Y+S+ + + D L+C NA T+N ++ Y+ + + + + + Sbjct: 1504 PVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQK 1563 Query: 237 MSKQAALLGNEDTAVEEPVPE-------VVPVQVETAKKSKKPSR 274 + K+ G E EE E V V+++ +K K R Sbjct: 1564 IEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDR 1608 >gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens] Length = 757 Score = 59.3 bits (142), Expect = 1e-08 Identities = 30/66 (45%), Positives = 37/66 (56%) Query: 161 FAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDT 220 F PVTD IAPGY I++ PMD T+K I +S EF+ D LM NA+ YN D Sbjct: 626 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDH 685 Query: 221 VYYKLA 226 Y +A Sbjct: 686 DVYHMA 691 >gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens] Length = 1235 Score = 59.3 bits (142), Expect = 1e-08 Identities = 30/66 (45%), Positives = 37/66 (56%) Query: 161 FAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDT 220 F PVTD IAPGY I++ PMD T+K I +S EF+ D LM NA+ YN D Sbjct: 732 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDH 791 Query: 221 VYYKLA 226 Y +A Sbjct: 792 DVYHMA 797 Score = 49.7 bits (117), Expect = 8e-06 Identities = 23/66 (34%), Positives = 36/66 (54%) Query: 161 FAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDT 220 F PV++ APGY ++K PMD ++K + +++ +F D LM NA+ YN D Sbjct: 1128 FLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDH 1187 Query: 221 VYYKLA 226 Y +A Sbjct: 1188 HVYHMA 1193 >gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens] Length = 951 Score = 59.3 bits (142), Expect = 1e-08 Identities = 30/66 (45%), Positives = 37/66 (56%) Query: 161 FAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDT 220 F PVTD IAPGY I++ PMD T+K I +S EF+ D LM NA+ YN D Sbjct: 805 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDH 864 Query: 221 VYYKLA 226 Y +A Sbjct: 865 DVYHMA 870 >gi|192807323 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform A [Homo sapiens] Length = 1679 Score = 58.9 bits (141), Expect = 1e-08 Identities = 59/294 (20%), Positives = 124/294 (42%), Gaps = 44/294 (14%) Query: 2 GKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGS---------GHDSSYY 52 G +H+K DY+D EK + + K+ G ++ + + S G Sbjct: 1370 GSRHRKEV--------DYSDSLTEK--QWLKKITGKDIHDTASSVARGLQFQRGLQFCTR 1419 Query: 53 DDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDP 112 ++ E + +++ ++KKS +++ D + R R+++ + + P Sbjct: 1420 ASKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPP 1479 Query: 113 GKKVEVEPP--PDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIA 170 +K+ PP + + +S+ +QL E F++ RK+ Sbjct: 1480 AEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKE-------------L 1526 Query: 171 PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYK---LAK 227 P Y +I+ P+DF +K++I ++Y+S+ + + D L+C NA T+N ++ Y+ + + Sbjct: 1527 PEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQ 1586 Query: 228 KILHAGFKMMSKQAALLGNEDTAVEEPVPE-------VVPVQVETAKKSKKPSR 274 + + + + K+ G E EE E V V+++ +K K R Sbjct: 1587 SVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDR 1640 >gi|192807314 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform C [Homo sapiens] Length = 1617 Score = 58.9 bits (141), Expect = 1e-08 Identities = 63/273 (23%), Positives = 119/273 (43%), Gaps = 48/273 (17%) Query: 37 SEVTELSGSGHDSSYYDDRSDHERERH-----KEKKKKKKKKSEKEKHLDD--EERRKRK 89 +EV L+ + + S H +E EK+ K K+ +E L++ EE R++K Sbjct: 1319 AEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKTLKAIEEGTLEEIEEEVRQKK 1378 Query: 90 EEKKRKREREHCDT-------EGEADDFDPGKKVEVEPPPDR--PVRACRTQPAEN---- 136 +KRKR+ + + + DD +K PP ++ P T+ + Sbjct: 1379 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA 1438 Query: 137 -----ESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIV 191 +S+ +QL E F++ RK+ P Y +I+ P+DF +K++I Sbjct: 1439 VIKYKDSSSGRQLSEVFIQLPSRKE-------------LPEYYELIRKPVDFKKIKERIR 1485 Query: 192 ANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYK---LAKKILHAGFKMMSKQAALLGNED 248 ++Y+S+ + + D L+C NA T+N ++ Y+ + + + + + + K+ G E Sbjct: 1486 NHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEES 1545 Query: 249 TAVEEPVPE-------VVPVQVETAKKSKKPSR 274 EE E V V+++ +K K R Sbjct: 1546 EEEEEGEEEGSESESRSVKVKIKLGRKEKAQDR 1578 >gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo sapiens] Length = 1905 Score = 58.9 bits (141), Expect = 1e-08 Identities = 29/75 (38%), Positives = 42/75 (56%) Query: 146 EHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADF 205 E L +++ D F PV + GY IIK+PMDF TM+++++ Y S EF AD Sbjct: 1803 EIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADA 1862 Query: 206 KLMCDNAMTYNRPDT 220 L+ DN T+N D+ Sbjct: 1863 LLVFDNCQTFNEDDS 1877 Score = 38.5 bits (88), Expect = 0.018 Identities = 27/95 (28%), Positives = 50/95 (52%), Gaps = 2/95 (2%) Query: 6 KKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEV-TELSGSGHDSSYYDDRSDHERERHK 64 KK +A+ + ED A K + K+ KV E T + G + + +S ++E K Sbjct: 694 KKLEAQETLNEEDKA-KIAKSKKKMRQKVQRGECQTTIQGQARNKRKQETKSLKQKEAKK 752 Query: 65 EKKKKKKKKSEKEKHLDDEERRKRKEEKKRKRERE 99 + K +K+K K++ L ++ +R++KE+ K K + E Sbjct: 753 KSKAEKEKGKTKQEKLKEKVKREKKEKVKMKEKEE 787 >gi|192807316 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform D [Homo sapiens] Length = 1616 Score = 58.5 bits (140), Expect = 2e-08 Identities = 62/284 (21%), Positives = 116/284 (40%), Gaps = 54/284 (19%) Query: 2 GKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERE 61 G +H+K DY+D EK LK + E + + +S +R+ Sbjct: 1337 GSRHRKEV--------DYSDSLTEKQWLKTLKA----IEEGTLEEIEEEVRQKKSSRKRK 1384 Query: 62 RHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPP 121 R + S + + DDE K++KKR R P +K+ PP Sbjct: 1385 RDSDAGSSTPTTSTRSRDKDDES----KKQKKRGRP--------------PAEKLSPNPP 1426 Query: 122 P-DRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP 180 + ++ + + + +QL E F++ RK+ P Y +I+ P Sbjct: 1427 NLTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRKE-------------LPEYYELIRKP 1473 Query: 181 MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYK---LAKKILHAGFKMM 237 +DF +K++I ++Y+S+ + + D L+C NA T+N ++ Y+ + + + + + + Sbjct: 1474 VDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKI 1533 Query: 238 SKQAALLGNEDTAVEEPVPE-------VVPVQVETAKKSKKPSR 274 K+ G E EE E V V+++ +K K R Sbjct: 1534 EKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDR 1577 >gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo sapiens] Length = 1483 Score = 58.5 bits (140), Expect = 2e-08 Identities = 58/193 (30%), Positives = 81/193 (41%), Gaps = 27/193 (13%) Query: 36 GSEVTELSGSGHDSSYYDDRSDHERERHKEKKKK----------KKKKSEKEKH--LDDE 83 G TE S S DS DD SD E E +E++++ + +K+ + KH + Sbjct: 1242 GRNYTEESAS-EDSE--DDESDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVIPPA 1298 Query: 84 ERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPPPDRPVRACRTQPAENESTPIQQ 143 R R+ KK R DD EV+ + R+ R Q E Q Sbjct: 1299 ARSGRRPGKKPHSTRRSQPKAPPVDD------AEVDELVLQTKRSSRRQSLE------LQ 1346 Query: 144 LLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKA 203 E L ++ + F PVT A Y +I HPMDF T+++K Y+SV EF Sbjct: 1347 KCEEILHKIVKYRFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLT 1406 Query: 204 DFKLMCDNAMTYN 216 D K + NA YN Sbjct: 1407 DMKQVFTNAEVYN 1419 Score = 30.0 bits (66), Expect = 6.3 Identities = 15/46 (32%), Positives = 30/46 (65%), Gaps = 2/46 (4%) Query: 56 SDHERERHKEKKKKKKKK--SEKEKHLDDEERRKRKEEKKRKRERE 99 S+ +R+ + +KK+++ KK EK K ++E +R E++KR ++E Sbjct: 539 SEEQRKEYLKKKREELKKKLKEKAKERREKEMLERLEKQKRYEDQE 584 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.129 0.362 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,773,793 Number of Sequences: 37866 Number of extensions: 1241329 Number of successful extensions: 24886 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 591 Number of HSP's successfully gapped in prelim test: 316 Number of HSP's that attempted gapping in prelim test: 9290 Number of HSP's gapped (non-prelim): 8544 length of query: 597 length of database: 18,247,518 effective HSP length: 108 effective length of query: 489 effective length of database: 14,157,990 effective search space: 6923257110 effective search space used: 6923257110 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.