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Search of human proteins with 23592220
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23592220 G protein-coupled receptor 26 [Homo sapiens]
(337 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23592220 G protein-coupled receptor 26 [Homo sapiens] 671 0.0
gi|36951034 G protein-coupled receptor 78 [Homo sapiens] 330 1e-90
gi|13236497 5-hydroxytryptamine receptor 5A [Homo sapiens] 87 3e-17
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 87 3e-17
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 87 3e-17
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 87 3e-17
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 87 3e-17
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 87 3e-17
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] 87 3e-17
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 84 2e-16
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 84 2e-16
gi|110618256 trace amine associated receptor 9 [Homo sapiens] 83 4e-16
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] 82 5e-16
gi|149944554 somatostatin receptor 4 [Homo sapiens] 82 5e-16
gi|21264324 trace amine associated receptor 1 [Homo sapiens] 82 7e-16
gi|222080109 orexin receptor 2 [Homo sapiens] 80 3e-15
gi|167000885 galanin receptor 1 [Homo sapiens] 77 2e-14
gi|4557857 somatostatin receptor 1 [Homo sapiens] 77 2e-14
gi|28173558 trace amine associated receptor 6 [Homo sapiens] 77 2e-14
gi|31083315 G protein-coupled receptor 45 [Homo sapiens] 76 5e-14
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi... 75 6e-14
gi|4557865 somatostatin receptor 5 [Homo sapiens] 75 8e-14
gi|4503905 galanin receptor 2 [Homo sapiens] 75 1e-13
gi|223633986 trace amine associated receptor 5 [Homo sapiens] 74 1e-13
gi|16751917 trace amine associated receptor 8 [Homo sapiens] 74 1e-13
gi|4885361 gastrin-releasing peptide receptor [Homo sapiens] 74 2e-13
gi|239757761 PREDICTED: similar to gastrin-releasing peptide rec... 74 2e-13
gi|4557861 somatostatin receptor 3 [Homo sapiens] 74 2e-13
gi|53828924 G protein-coupled receptor 7 [Homo sapiens] 72 9e-13
gi|30581164 neuropeptides B/W receptor 2 [Homo sapiens] 72 9e-13
>gi|23592220 G protein-coupled receptor 26 [Homo sapiens]
Length = 337
Score = 671 bits (1730), Expect = 0.0
Identities = 337/337 (100%), Positives = 337/337 (100%)
Query: 1 MNSWDAGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNM 60
MNSWDAGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNM
Sbjct: 1 MNSWDAGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNM 60
Query: 61 PLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRL 120
PLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRL
Sbjct: 61 PLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRL 120
Query: 121 RDAALMVAYTWLHALTFPAAALALSWLGFHQLYASCTLCSRRPDERLRFAVFTGAFHALS 180
RDAALMVAYTWLHALTFPAAALALSWLGFHQLYASCTLCSRRPDERLRFAVFTGAFHALS
Sbjct: 121 RDAALMVAYTWLHALTFPAAALALSWLGFHQLYASCTLCSRRPDERLRFAVFTGAFHALS 180
Query: 181 FLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRAT 240
FLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRAT
Sbjct: 181 FLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRAT 240
Query: 241 KKISTFIGTFLVCFAPYVITRLVELFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQ 300
KKISTFIGTFLVCFAPYVITRLVELFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQ
Sbjct: 241 KKISTFIGTFLVCFAPYVITRLVELFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQ 300
Query: 301 YRKSCKEILNRLLHRRSIHSSGLTGDSHSQNILPVSE 337
YRKSCKEILNRLLHRRSIHSSGLTGDSHSQNILPVSE
Sbjct: 301 YRKSCKEILNRLLHRRSIHSSGLTGDSHSQNILPVSE 337
>gi|36951034 G protein-coupled receptor 78 [Homo sapiens]
Length = 363
Score = 330 bits (845), Expect = 1e-90
Identities = 170/327 (51%), Positives = 222/327 (67%), Gaps = 4/327 (1%)
Query: 1 MNSWDAGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNM 60
M +A LAGLLV + V+LLSNALVLLC +SA++R +A + +NL+ G+LL ++M
Sbjct: 1 MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDM 60
Query: 61 PLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRL 120
P TL GV+ R P+ C++ FLDTFLA+N+ LS+AALS D+W+AV FPL Y ++R
Sbjct: 61 PFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRP 120
Query: 121 RDAALMVAYTWLHALTFPAAALALSWLGFHQLYASCTLCSRRPDERLRFAVFTGAFHALS 180
R A L++ W +L F AAL SWLG+ +ASC+L ER RFA FT HA+
Sbjct: 121 RYAGLLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHAVG 180
Query: 181 FLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRAT 240
F+L VLC T L+V +VAR HC+R+D +TM+ L LL DLHPSVR+RCL +QKRRR RAT
Sbjct: 181 FVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHRAT 240
Query: 241 KKISTFIGTFLVCFAPYVITRLVELFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQ 300
+KI I TFL+CFAPYV+TRL EL V + + WG+LSKCL YSKA +DPF YSLLR
Sbjct: 241 RKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQWGILSKCLTYSKAVADPFTYSLLRRP 300
Query: 301 YRKSCKEILNRLLHR----RSIHSSGL 323
+R+ +++RLL R S H S L
Sbjct: 301 FRQVLAGMVHRLLKRTPRPASTHDSSL 327
>gi|13236497 5-hydroxytryptamine receptor 5A [Homo sapiens]
Length = 357
Score = 86.7 bits (213), Expect = 3e-17
Identities = 70/308 (22%), Positives = 132/308 (42%), Gaps = 29/308 (9%)
Query: 23 NALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQ-PAGDRLCRL 81
N LVL +L R P ++ ++L + MPL+L ++ R+ G RLC+L
Sbjct: 58 NLLVLATILRVRTFHR-VPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQL 116
Query: 82 AAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMVAYTWLHALTFPAAA 141
D S+ ++ A+++DR+ ++ + Y + R + +M+A TW + A
Sbjct: 117 WIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAP 176
Query: 142 LALSWLGFHQLYASCTLCSRRPDERLRFAVFT--GAFHALSFLLSFVVLCCTYLKVLKVA 199
L W + + SR P +AVF+ GAF+ L V+ Y K+ K A
Sbjct: 177 LLFGWGETYSEGSEECQVSREPS----YAVFSTVGAFY-----LPLCVVLFVYWKIYKAA 227
Query: 200 RFHCKRIDVITMQTLVLLVDLHPSVRERCL----------------EEQKRRRQRATKKI 243
+F ++ + V++ S ++ + ++++ QRA +
Sbjct: 228 KFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMV 287
Query: 244 STFIGTFLVCFAPYVITRLVELFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRK 303
IG F++C+ P+ +T L+ + I + W + L YS + +P +Y+ Y
Sbjct: 288 GILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNS 347
Query: 304 SCKEILNR 311
+ K +R
Sbjct: 348 AFKNFFSR 355
>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
Length = 359
Score = 86.7 bits (213), Expect = 3e-17
Identities = 71/300 (23%), Positives = 130/300 (43%), Gaps = 12/300 (4%)
Query: 18 VSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDR 77
+++L N LV++ + +R+ F ++L +LL +V+ MP +V G+
Sbjct: 32 MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEV 91
Query: 78 LCRLAAFLDTFLAANSMLSMAALSIDRWVAVVF-PLSYRAKMRLRDAALMVAYTWLHALT 136
C + LD L S+ + +S+DR+ A+ PL YR KM ALM+ W+
Sbjct: 92 FCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTF 151
Query: 137 FPAAALALSW--LGFHQLYASCTLCSRRPDERLRFAV---FTGAFHALSFLLSFVVLCCT 191
+ W +G L F V + ++F + F+++
Sbjct: 152 ISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLA 211
Query: 192 YLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFL 251
Y ++ A+ H +I ++ Q + P ++ + R +A K + +G F
Sbjct: 212 YYRIYVTAKEHAHQIQML--QRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFC 269
Query: 252 VCFAPYVITRLVELF--STVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKSCKEIL 309
+C+AP+ +T +V+ F TVP G W L Y + +PF+Y+ L +R++ IL
Sbjct: 270 LCWAPFFVTNIVDPFIDYTVP-GQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327
>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
Length = 428
Score = 86.7 bits (213), Expect = 3e-17
Identities = 71/300 (23%), Positives = 130/300 (43%), Gaps = 12/300 (4%)
Query: 18 VSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDR 77
+++L N LV++ + +R+ F ++L +LL +V+ MP +V G+
Sbjct: 32 MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEV 91
Query: 78 LCRLAAFLDTFLAANSMLSMAALSIDRWVAVVF-PLSYRAKMRLRDAALMVAYTWLHALT 136
C + LD L S+ + +S+DR+ A+ PL YR KM ALM+ W+
Sbjct: 92 FCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTF 151
Query: 137 FPAAALALSW--LGFHQLYASCTLCSRRPDERLRFAV---FTGAFHALSFLLSFVVLCCT 191
+ W +G L F V + ++F + F+++
Sbjct: 152 ISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLA 211
Query: 192 YLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFL 251
Y ++ A+ H +I ++ Q + P ++ + R +A K + +G F
Sbjct: 212 YYRIYVTAKEHAHQIQML--QRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFC 269
Query: 252 VCFAPYVITRLVELF--STVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKSCKEIL 309
+C+AP+ +T +V+ F TVP G W L Y + +PF+Y+ L +R++ IL
Sbjct: 270 LCWAPFFVTNIVDPFIDYTVP-GQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327
>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
Length = 360
Score = 86.7 bits (213), Expect = 3e-17
Identities = 71/300 (23%), Positives = 130/300 (43%), Gaps = 12/300 (4%)
Query: 18 VSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDR 77
+++L N LV++ + +R+ F ++L +LL +V+ MP +V G+
Sbjct: 32 MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEV 91
Query: 78 LCRLAAFLDTFLAANSMLSMAALSIDRWVAVVF-PLSYRAKMRLRDAALMVAYTWLHALT 136
C + LD L S+ + +S+DR+ A+ PL YR KM ALM+ W+
Sbjct: 92 FCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTF 151
Query: 137 FPAAALALSW--LGFHQLYASCTLCSRRPDERLRFAV---FTGAFHALSFLLSFVVLCCT 191
+ W +G L F V + ++F + F+++
Sbjct: 152 ISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLA 211
Query: 192 YLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFL 251
Y ++ A+ H +I ++ Q + P ++ + R +A K + +G F
Sbjct: 212 YYRIYVTAKEHAHQIQML--QRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFC 269
Query: 252 VCFAPYVITRLVELF--STVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKSCKEIL 309
+C+AP+ +T +V+ F TVP G W L Y + +PF+Y+ L +R++ IL
Sbjct: 270 LCWAPFFVTNIVDPFIDYTVP-GQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327
>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
Length = 387
Score = 86.7 bits (213), Expect = 3e-17
Identities = 71/300 (23%), Positives = 130/300 (43%), Gaps = 12/300 (4%)
Query: 18 VSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDR 77
+++L N LV++ + +R+ F ++L +LL +V+ MP +V G+
Sbjct: 32 MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEV 91
Query: 78 LCRLAAFLDTFLAANSMLSMAALSIDRWVAVVF-PLSYRAKMRLRDAALMVAYTWLHALT 136
C + LD L S+ + +S+DR+ A+ PL YR KM ALM+ W+
Sbjct: 92 FCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTF 151
Query: 137 FPAAALALSW--LGFHQLYASCTLCSRRPDERLRFAV---FTGAFHALSFLLSFVVLCCT 191
+ W +G L F V + ++F + F+++
Sbjct: 152 ISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLA 211
Query: 192 YLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFL 251
Y ++ A+ H +I ++ Q + P ++ + R +A K + +G F
Sbjct: 212 YYRIYVTAKEHAHQIQML--QRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFC 269
Query: 252 VCFAPYVITRLVELF--STVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKSCKEIL 309
+C+AP+ +T +V+ F TVP G W L Y + +PF+Y+ L +R++ IL
Sbjct: 270 LCWAPFFVTNIVDPFIDYTVP-GQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327
>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
Length = 378
Score = 86.7 bits (213), Expect = 3e-17
Identities = 71/300 (23%), Positives = 130/300 (43%), Gaps = 12/300 (4%)
Query: 18 VSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDR 77
+++L N LV++ + +R+ F ++L +LL +V+ MP +V G+
Sbjct: 32 MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEV 91
Query: 78 LCRLAAFLDTFLAANSMLSMAALSIDRWVAVVF-PLSYRAKMRLRDAALMVAYTWLHALT 136
C + LD L S+ + +S+DR+ A+ PL YR KM ALM+ W+
Sbjct: 92 FCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTF 151
Query: 137 FPAAALALSW--LGFHQLYASCTLCSRRPDERLRFAV---FTGAFHALSFLLSFVVLCCT 191
+ W +G L F V + ++F + F+++
Sbjct: 152 ISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLA 211
Query: 192 YLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFL 251
Y ++ A+ H +I ++ Q + P ++ + R +A K + +G F
Sbjct: 212 YYRIYVTAKEHAHQIQML--QRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFC 269
Query: 252 VCFAPYVITRLVELF--STVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKSCKEIL 309
+C+AP+ +T +V+ F TVP G W L Y + +PF+Y+ L +R++ IL
Sbjct: 270 LCWAPFFVTNIVDPFIDYTVP-GQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327
>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
Length = 388
Score = 86.7 bits (213), Expect = 3e-17
Identities = 71/300 (23%), Positives = 130/300 (43%), Gaps = 12/300 (4%)
Query: 18 VSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDR 77
+++L N LV++ + +R+ F ++L +LL +V+ MP +V G+
Sbjct: 32 MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEV 91
Query: 78 LCRLAAFLDTFLAANSMLSMAALSIDRWVAVVF-PLSYRAKMRLRDAALMVAYTWLHALT 136
C + LD L S+ + +S+DR+ A+ PL YR KM ALM+ W+
Sbjct: 92 FCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTF 151
Query: 137 FPAAALALSW--LGFHQLYASCTLCSRRPDERLRFAV---FTGAFHALSFLLSFVVLCCT 191
+ W +G L F V + ++F + F+++
Sbjct: 152 ISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLA 211
Query: 192 YLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFL 251
Y ++ A+ H +I ++ Q + P ++ + R +A K + +G F
Sbjct: 212 YYRIYVTAKEHAHQIQML--QRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFC 269
Query: 252 VCFAPYVITRLVELF--STVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKSCKEIL 309
+C+AP+ +T +V+ F TVP G W L Y + +PF+Y+ L +R++ IL
Sbjct: 270 LCWAPFFVTNIVDPFIDYTVP-GQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327
>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
Length = 397
Score = 83.6 bits (205), Expect = 2e-16
Identities = 69/306 (22%), Positives = 134/306 (43%), Gaps = 32/306 (10%)
Query: 26 VLLCLLHSADIR-RQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDRLCRLAAF 84
V++CL + R R F ++L +LL ++ +P + ++ + G C +
Sbjct: 37 VVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTS 96
Query: 85 LDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMVAYTWLHALTFPAAALAL 144
LD L S+L++ +S+DR+ AV+ PL Y + A+ + W+ ++T ++ L
Sbjct: 97 LDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHL 156
Query: 145 SWLGFHQLYA---SCTLCSRRPDERLRFAVFTGAFHALSFLLSFVVLCCTYLKVLKVARF 201
W ++ + + C + +E V+ ++F L +++C TY ++ KVAR
Sbjct: 157 GWNSRNETSKGNHTTSKCKVQVNE-----VYGLVDGLVTFYLPLLIMCITYYRIFKVARD 211
Query: 202 HCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFLVCFAPYVITR 261
KRI+ I+ + R +AT ++ +G F++C+ PY
Sbjct: 212 QAKRINHISSWKAATI-----------------REHKATVTLAAVMGAFIICWFPYFTAF 254
Query: 262 LVE-LFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKS-----CKEILNRLLHR 315
+ L I + L Y+ +A +P +Y+ L +R C + NR H+
Sbjct: 255 VYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHK 314
Query: 316 RSIHSS 321
S+ S+
Sbjct: 315 TSLRSN 320
>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
Length = 359
Score = 83.6 bits (205), Expect = 2e-16
Identities = 69/306 (22%), Positives = 134/306 (43%), Gaps = 32/306 (10%)
Query: 26 VLLCLLHSADIR-RQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDRLCRLAAF 84
V++CL + R R F ++L +LL ++ +P + ++ + G C +
Sbjct: 37 VVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTS 96
Query: 85 LDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMVAYTWLHALTFPAAALAL 144
LD L S+L++ +S+DR+ AV+ PL Y + A+ + W+ ++T ++ L
Sbjct: 97 LDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHL 156
Query: 145 SWLGFHQLYA---SCTLCSRRPDERLRFAVFTGAFHALSFLLSFVVLCCTYLKVLKVARF 201
W ++ + + C + +E V+ ++F L +++C TY ++ KVAR
Sbjct: 157 GWNSRNETSKGNHTTSKCKVQVNE-----VYGLVDGLVTFYLPLLIMCITYYRIFKVARD 211
Query: 202 HCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFLVCFAPYVITR 261
KRI+ I+ + R +AT ++ +G F++C+ PY
Sbjct: 212 QAKRINHISSWKAATI-----------------REHKATVTLAAVMGAFIICWFPYFTAF 254
Query: 262 LVE-LFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKS-----CKEILNRLLHR 315
+ L I + L Y+ +A +P +Y+ L +R C + NR H+
Sbjct: 255 VYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHK 314
Query: 316 RSIHSS 321
S+ S+
Sbjct: 315 TSLRSN 320
>gi|110618256 trace amine associated receptor 9 [Homo sapiens]
Length = 348
Score = 82.8 bits (203), Expect = 4e-16
Identities = 69/330 (20%), Positives = 138/330 (41%), Gaps = 26/330 (7%)
Query: 4 WDAGLAGLLVGTMG----VSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVN 59
+ G +L +G ++ N LV++ +LH + L +L C + L V
Sbjct: 27 YSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIA-SLACADFLVGVTV 85
Query: 60 MPLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMR 119
MP + V GD C+ DT S+ + +S+DR++AV PL+Y K
Sbjct: 86 MPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFT 145
Query: 120 LRDAALMVAYTWLHALTFPAAAL--ALSWLGFHQLYASCTL---CSRRPDERLRFAVFTG 174
+ + + + +W ++T+ + + G +L + T C ++ F
Sbjct: 146 VSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCF-- 203
Query: 175 AFHALSFLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKR 234
L F + V + Y K+ VA+ ++I+ Q S E E +
Sbjct: 204 ----LLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQA--------QSSSESYKERVAK 251
Query: 235 RRQRATKKISTFIGTFLVCFAPYVITRLVELFSTVPIGSH-WGVLSKCLAYSKAASDPFV 293
R ++A K + + FLV + PY++ +++ + + + +L C+ Y+ +A +P +
Sbjct: 252 RERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYN-SAMNPLI 310
Query: 294 YSLLRHQYRKSCKEILNRLLHRRSIHSSGL 323
Y+ + K+ K I++ + R ++ L
Sbjct: 311 YAFFYQWFGKAIKLIVSGKVLRTDSSTTNL 340
>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
Length = 402
Score = 82.4 bits (202), Expect = 5e-16
Identities = 71/314 (22%), Positives = 132/314 (42%), Gaps = 26/314 (8%)
Query: 18 VSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDR 77
+++L N LV++ + +R+ F ++L +LL +V+ MP +V G+
Sbjct: 32 MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEV 91
Query: 78 LCRLAAFLDTFLAANSMLSMAALSIDRWVAVVF-PLSYRAKMRLRDAALMVAYTWLHALT 136
C + LD L S+ + +S+DR+ A+ PL YR KM ALM+ W+
Sbjct: 92 FCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTF 151
Query: 137 FPAAALALSW-------------LGFHQLYASCTLCSRRPDERLRFAVF------TGAFH 177
+ W G Q + + + + VF
Sbjct: 152 ISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYCVFMVNKPYAITCS 211
Query: 178 ALSFLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQ 237
++F + F+++ Y ++ A+ H +I + +Q + P ++ + R
Sbjct: 212 VVAFYIPFLLMVLAYYRIYVTAKEHAHQIQM--LQRAGASSESRPQSADQHSTHRMRTET 269
Query: 238 RATKKISTFIGTFLVCFAPYVITRLVELF--STVPIGSHWGVLSKCLAYSKAASDPFVYS 295
+A K + +G F +C+AP+ +T +V+ F TVP G W L Y + +PF+Y+
Sbjct: 270 KAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVP-GQVWTAF-LWLGYINSGLNPFLYA 327
Query: 296 LLRHQYRKSCKEIL 309
L +R++ IL
Sbjct: 328 FLNKSFRRAFLIIL 341
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 82.4 bits (202), Expect = 5e-16
Identities = 76/295 (25%), Positives = 131/295 (44%), Gaps = 31/295 (10%)
Query: 18 VSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDR 77
V L+ NALV+ +L A ++ A ++ LNL + L ++++P + + P G
Sbjct: 60 VGLVGNALVIFVILRYAKMKT-ATNIYLLNLAVADELF-MLSVPFVASSAALRHWPFGSV 117
Query: 78 LCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMVAYTWLHAL-- 135
LCR +D S+ + LS+DR+VAVV PL R A L+ WL +L
Sbjct: 118 LCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLV 177
Query: 136 TFPAAALALSWLGFHQLYASCTLCSRRPDERLRFAVFTGAFHALSFLLSFVVLCCTYLKV 195
T P A A + +C L P F V+T L FLL + + YL
Sbjct: 178 TLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYT---FLLGFLLPVLAIGLCYL-- 232
Query: 196 LKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRR-RQRATKKISTFIGTFLVCF 254
L+V +V R +Q+RR ++ T+ + + F++C+
Sbjct: 233 --------------------LIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCW 272
Query: 255 APYVITRLVELFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKSCKEIL 309
P+ + +L+ LF T + + +S L+Y+ + ++P +Y L +R+ + +L
Sbjct: 273 MPFYVVQLLNLFVT-SLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVL 326
>gi|21264324 trace amine associated receptor 1 [Homo sapiens]
Length = 339
Score = 82.0 bits (201), Expect = 7e-16
Identities = 73/318 (22%), Positives = 141/318 (44%), Gaps = 24/318 (7%)
Query: 2 NSWD----AGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTV 57
N+W A L L+V + +L+ N +V++ + H + L T LL +
Sbjct: 16 NNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCL 75
Query: 58 VNMPLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAK 117
V MP ++ G+ C++ D L++ S+ ++ +SIDR+ AV PL Y+AK
Sbjct: 76 V-MPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAK 134
Query: 118 MRLRDAALMVAYTWL--HALTFPAAALALSWLGFHQLYASCTLCSRRPDERLRFAVFTGA 175
M + +M+ +W F L L++ G ++Y C R + F+ +G
Sbjct: 135 MNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHC--RGGCSVFFSKISG- 191
Query: 176 FHALSFLLSFV----VLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEE 231
L+F+ SF ++ C Y ++ +A+ + I Q L + +++ +
Sbjct: 192 --VLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDAN-QKLQIGLEMKNGI------- 241
Query: 232 QKRRRQRATKKISTFIGTFLVCFAPYVITRLVELFSTVPIGSHWGVLSKCLAYSKAASDP 291
+ + ++A K + +G FL+C+ P+ I +++ F I + Y + +P
Sbjct: 242 SQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNP 301
Query: 292 FVYSLLRHQYRKSCKEIL 309
VY+ +RK+ K +L
Sbjct: 302 MVYAFFYPWFRKALKMML 319
>gi|222080109 orexin receptor 2 [Homo sapiens]
Length = 444
Score = 79.7 bits (195), Expect = 3e-15
Identities = 70/322 (21%), Positives = 145/322 (45%), Gaps = 26/322 (8%)
Query: 8 LAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGV 67
+AG ++ V+L+ N LV + + + +R F +NL+ ++L T+ +P TL
Sbjct: 58 IAGYII-VFVVALIGNVLVCVAVWKNHHMRT-VTNYFIVNLSLADVLVTITCLPATLVVD 115
Query: 68 VAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMV 127
+ + G LC++ +L T + S+L+++ +++DRW A+ PL +++ + ++++
Sbjct: 116 ITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVI 175
Query: 128 AYTWLHALTFPAAALALSWLGFHQLYASCTLCSRRPDERLRFAVFTGAFHALSFLLSFVV 187
+ + P A + F L TL + DER ++ +H FL++++
Sbjct: 176 IWIVSCIIMIPQAIVMECSTVFPGLANKTTLFT-VCDERWGGEIYPKMYHICFFLVTYMA 234
Query: 188 -LCCTYLKVLKVAR-FHCKRIDVITMQTLVLLVDLHPSVRER--------------CLEE 231
LC L L++ R C++I + L P + R +
Sbjct: 235 PLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIK 294
Query: 232 QKRRRQRATKKISTFIGTFLVCFAPY----VITRLVELFSTVPIGS---HWGVLSKCLAY 284
Q R R++ + + + F +C+ P V+ R+ +F+ W S L Y
Sbjct: 295 QIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVY 354
Query: 285 SKAASDPFVYSLLRHQYRKSCK 306
+ +A++P +Y+ L ++R+ K
Sbjct: 355 ANSAANPIIYNFLSGKFREEFK 376
>gi|167000885 galanin receptor 1 [Homo sapiens]
Length = 349
Score = 77.4 bits (189), Expect = 2e-14
Identities = 80/330 (24%), Positives = 143/330 (43%), Gaps = 33/330 (10%)
Query: 12 LVGTMGVSLLSNALVLLCLLHSADIR-RQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQ 70
L+ +GV L N+LV+ L S + R LF LNL+ +L + +P
Sbjct: 42 LIFALGV--LGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALP 99
Query: 71 RQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMVAYT 130
G +C+ + T S+ ++AA+S+DR+VA+V + R+A L V
Sbjct: 100 TWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCI 159
Query: 131 WLHALTFPAAALALSWLGFHQLYASCTLCSRR-PDERLRFAVFTGAFHALSFLLSFVVLC 189
W ++ A+ +A FH ++ T C + PD R + A F +LL +++C
Sbjct: 160 WALSIAM-ASPVAYHQGLFHPRASNQTFCWEQWPDPRHKKAYVVCTF-VFGYLLPLLLIC 217
Query: 190 CTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGT 249
Y KVL LH ++ + + +++ A + + +
Sbjct: 218 FCYAKVLN---------------------HLHKKLKNMSKKSEASKKKTA-QTVLVVVVV 255
Query: 250 FLVCFAPYVITRL---VELFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKSCK 306
F + + P+ I L +F P + + + CLAYS ++ +P +Y+ L +RK+ K
Sbjct: 256 FGISWLPHHIIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYK 315
Query: 307 EILNRLLHRRSIHSSGLTGDSHSQNILPVS 336
++ + R+ H S T +S S+ P S
Sbjct: 316 QVFKCHI-RKDSHLSD-TKESKSRIDTPPS 343
>gi|4557857 somatostatin receptor 1 [Homo sapiens]
Length = 391
Score = 77.0 bits (188), Expect = 2e-14
Identities = 67/295 (22%), Positives = 131/295 (44%), Gaps = 30/295 (10%)
Query: 18 VSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDR 77
V L N++V+ +L A ++ A ++ LNL + L ++++P + + + P G
Sbjct: 71 VGLCGNSMVIYVILRYAKMKT-ATNIYILNLAIADELL-MLSVPFLVTSTLLRHWPFGAL 128
Query: 78 LCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMVAYTWLHALTF 137
LCRL +D S+ + LS+DR+VAVV P+ R A ++ W+ +L
Sbjct: 129 LCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLV 188
Query: 138 PAAALALSWLGFH-QLYASCTLCSRRPDER--LRFAVFTGAFHALSFLLSFVVLCCTYLK 194
+ S + +C + P +R + F ++T + FLL +C Y+
Sbjct: 189 ILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYT---FLMGFLLPVGAICLCYVL 245
Query: 195 VLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFLVCF 254
++ R +V L ++R KR ++ T + + F++C+
Sbjct: 246 IIAKMR----------------MVALKAGWQQR-----KRSERKITLMVMMVVMVFVICW 284
Query: 255 APYVITRLVELFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKSCKEIL 309
P+ + +LV +F+ + LS L Y+ + ++P +Y L +++S + IL
Sbjct: 285 MPFYVVQLVNVFAEQD-DATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRIL 338
>gi|28173558 trace amine associated receptor 6 [Homo sapiens]
Length = 345
Score = 77.0 bits (188), Expect = 2e-14
Identities = 68/299 (22%), Positives = 125/299 (41%), Gaps = 24/299 (8%)
Query: 18 VSLLSNALVLLCLLHSADIRRQAPALFTL-NLTCGNLLCTVVNMPLTLAGVVAQRQPAGD 76
+++ N LV++ +LH + +P F + +L C + L V MP ++ V G
Sbjct: 45 LAVFGNLLVMISILHFKQLH--SPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGR 102
Query: 77 RLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMVAYTWLHALT 136
C D +S+ + +SIDR++AV PL Y K + + + ++ +W+ L
Sbjct: 103 SFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLM 162
Query: 137 FPAAALALSWL--GFHQLYASCTL---CSRRPDERLRFAVFTGAFHALSFLLSFVVLCCT 191
+ A G +L + C ++ F LSF + ++
Sbjct: 163 YSGAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDF------LSFFIPTFIMIIL 216
Query: 192 YLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFL 251
Y + VAR K+I+ +T S E RR ++A K + + F+
Sbjct: 217 YGNIFLVARRQAKKIENTGSKT--------ESSSESYKARVARRERKAAKTLGVTVVAFM 268
Query: 252 VCFAPYVITRLVELF-STVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKSCKEIL 309
+ + PY I L++ F + + + C AY +A +P +Y+L +RK+ K I+
Sbjct: 269 ISWLPYSIDSLIDAFMGFITPACIYEICCWC-AYYNSAMNPLIYALFYPWFRKAIKVIV 326
>gi|31083315 G protein-coupled receptor 45 [Homo sapiens]
Length = 372
Score = 75.9 bits (185), Expect = 5e-14
Identities = 70/300 (23%), Positives = 131/300 (43%), Gaps = 15/300 (5%)
Query: 18 VSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDR 77
V L N +V + +++ R A L L +++ ++ MP T ++ R GD
Sbjct: 47 VGFLGNTVVCI-IVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAVTLITVRWHFGDH 105
Query: 78 LCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMVAYTWLHALTF 137
CRL+A L F + + +S+DR++ +V + K+ R A +++A +W+ L+F
Sbjct: 106 FCRLSATLYWFFVLEGVAILLIISVDRFLIIV---QRQDKLNPRRAKVIIAVSWV--LSF 160
Query: 138 PAAALALSWLGFHQLYASCTLCSRRPDERLRFAVFTGAFHALSFLLSFVVLCCTYLKVLK 197
A +L+ ++ A C E + F F V+ C Y+ +L
Sbjct: 161 CIAGPSLTGWTLVEVPARAPQCVLGYTELPADRAYVVTLVVAVFFAPFGVMLCAYMCILN 220
Query: 198 VARFHCKRI----DVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFLVC 253
R + R+ D + ++ L L R++ + + +A I F +C
Sbjct: 221 TVRKNAVRVHNQSDSLDLRQLT-RAGLRRLQRQQQVSVDLSFKTKAFTTILILFVGFSLC 279
Query: 254 FAPYVITRLVELFS-TVPIGSHWGVLSKC---LAYSKAASDPFVYSLLRHQYRKSCKEIL 309
+ P+ + L+ +FS GS + S C L+Y K+ +P VY ++R++C E+L
Sbjct: 280 WLPHSVYSLLSVFSQRFYCGSSFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELL 339
>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
sapiens]
Length = 440
Score = 75.5 bits (184), Expect = 6e-14
Identities = 70/317 (22%), Positives = 131/317 (41%), Gaps = 25/317 (7%)
Query: 8 LAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGV 67
+A L + ++ +N+L L+ L+ + R F ++L +L+ +V MP +
Sbjct: 29 VAAALCVVIALTAAANSL-LIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNA 87
Query: 68 VAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMV 127
+ R LC L D + S+L++ +S+DR++ ++ PL Y+ +M A +V
Sbjct: 88 LYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALV 147
Query: 128 AYTWLHALTFPAAALALSW--LGFHQ--LYASCTLCSRRPDERLRFAVFTGAFHALSFLL 183
W A L L W LG + + C L + P F L+F L
Sbjct: 148 LGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLASLP--------FVLVASGLTFFL 199
Query: 184 SFVVLCCTYLKVLKVARFHCKRIDVIT-------MQTLVLLVDLHPSVR----ERCLEEQ 232
+C TY ++L AR ++ +T +TL + P V R +
Sbjct: 200 PSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKH 259
Query: 233 KRRRQRATKKISTFIGTFLVCFAPYVITRLVELFSTVPIGSHWGVLSKCLAYSKAASDPF 292
R+ +A+ + +G F V + P+ + +V+ + VL+ L Y + +P
Sbjct: 260 SRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLT-WLGYCNSTMNPI 318
Query: 293 VYSLLRHQYRKSCKEIL 309
+Y L ++++ L
Sbjct: 319 IYPLFMRDFKRALGRFL 335
>gi|4557865 somatostatin receptor 5 [Homo sapiens]
Length = 364
Score = 75.1 bits (183), Expect = 8e-14
Identities = 77/305 (25%), Positives = 132/305 (43%), Gaps = 39/305 (12%)
Query: 11 LLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQ 70
LLV G+ N LV+ +L A ++ ++ LNL ++L ++ +P A
Sbjct: 48 LLVCAAGLG--GNTLVIYVVLRFAKMKT-VTNIYILNLAVADVLY-MLGLPFLATQNAAS 103
Query: 71 RQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMVAYT 130
P G LCRL LD S+ + +S+DR++AVV PLS R R A L A
Sbjct: 104 FWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAA 163
Query: 131 WLHALTFPAAALALSWLGFHQLYASCTLCSRRPDE-RLRFAVFTGAFHALSFLLSFVVLC 189
W+ +L ++L L F + T + P+ L AVF L F +V+C
Sbjct: 164 WVLSL-----CMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVIC 218
Query: 190 CTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGT 249
YL ++ R VR C+ ++R ++ T+ + +
Sbjct: 219 LCYLLIVVKVR--------------------AAGVRVGCV--RRRSERKVTRMVLVVVLV 256
Query: 250 FLVCFAPYVITRLVELFSTVP-----IGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKS 304
F C+ P+ +V L +P G ++ V+ L+Y+ + ++P +Y L +R+S
Sbjct: 257 FAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVV--ILSYANSCANPVLYGFLSDNFRQS 314
Query: 305 CKEIL 309
+++L
Sbjct: 315 FQKVL 319
>gi|4503905 galanin receptor 2 [Homo sapiens]
Length = 387
Score = 74.7 bits (182), Expect = 1e-13
Identities = 82/314 (26%), Positives = 131/314 (41%), Gaps = 33/314 (10%)
Query: 12 LVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQR 71
LVGT+G N LVL LL LF LNL +L + +P
Sbjct: 37 LVGTVG-----NTLVLAVLLRGGQAV-STTNLFILNLGVADLCFILCCVPFQATIYTLDG 90
Query: 72 QPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMVAYTW 131
G LC+ FL S ++AA+S+DR++A+ +PL R R+A + W
Sbjct: 91 WVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIW 150
Query: 132 LHALTFPAAALALSWLGFHQLYASCTLCSRRPDERLRFAVFTGAFHALSFLLSFVVLCCT 191
+L F + LS+ QL A+ T+C R A+ F S+LL +VL T
Sbjct: 151 GLSLLF--SGPYLSYYRQSQL-ANLTVCHPAWSAPRRRAMDICTF-VFSYLLPVLVLGLT 206
Query: 192 YLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFL 251
Y + L R+ + +D + + +R +++ T+ I F
Sbjct: 207 YARTL---RYLWRAVDPVAAGS-----------------GARRAKRKVTRMILIVAALFC 246
Query: 252 VCFAPYVITRLVELFSTVPIGS---HWGVLSKCLAYSKAASDPFVYSLLRHQYRKSCKEI 308
+C+ P+ L F P+ +LS ++Y+ + +P VY+L+ +RK + I
Sbjct: 247 LCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTI 306
Query: 309 LNRLLHRRSIHSSG 322
LL R +SG
Sbjct: 307 CAGLLGRAPGRASG 320
>gi|223633986 trace amine associated receptor 5 [Homo sapiens]
Length = 337
Score = 74.3 bits (181), Expect = 1e-13
Identities = 74/315 (23%), Positives = 129/315 (40%), Gaps = 47/315 (14%)
Query: 9 AGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTL-NLTCGNLLCTVVNMPLTLAGV 67
AG+L+ +G ++ A+ LH+ P F L +L ++ ++ +PL+
Sbjct: 43 AGMLIIVLGNVFVAFAVSYFKALHT-------PTNFLLLSLALADMFLGLLVLPLSTIRS 95
Query: 68 VAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDA---- 123
V GD LCRL +LDT S+ + +SIDR A+ PL Y +K +R A
Sbjct: 96 VESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYI 155
Query: 124 ----ALMVAYTWLHALTFPAAALALSWLGFHQLYASCTLCSRRPDERLRFAVFTGAFHAL 179
+ AYT L T WL SC L + F G +
Sbjct: 156 LAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLLLNK---------FWGWLNFP 206
Query: 180 SFLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRA 239
F + +++ Y+K+ VA ++I ++ + L + ++A
Sbjct: 207 LFFVPCLIMISLYVKIFVVATRQAQQITTLS----------------KSLAGAAKHERKA 250
Query: 240 TKKISTFIGTFLVCFAPYVITRLVEL---FSTVPIGSHWGVLSKCLAYSKAASDPFVYSL 296
K + +G +L+C+ P+ I +V+ F T P+ + AY +A +P +Y
Sbjct: 251 AKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFD---IFIWFAYFNSACNPIIYVF 307
Query: 297 LRHQYRKSCKEILNR 311
+RK+ K L++
Sbjct: 308 SYQWFRKALKLTLSQ 322
>gi|16751917 trace amine associated receptor 8 [Homo sapiens]
Length = 342
Score = 74.3 bits (181), Expect = 1e-13
Identities = 63/299 (21%), Positives = 130/299 (43%), Gaps = 22/299 (7%)
Query: 18 VSLLSNALVLLCLLHSADIRRQAPALFTL-NLTCGNLLCTVVNMPLTLAGVVAQRQPAGD 76
+++ N LV+ +LH + +P F + +L C + L V M ++ V G
Sbjct: 44 LAVFGNLLVMTSVLHFKQLH--SPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGA 101
Query: 77 RLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMVAYTWLHALT 136
+ C L + D +S+L + + IDR++ V PL Y K + + + ++ +W+ LT
Sbjct: 102 KFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLT 161
Query: 137 FPAAAL--ALSWLGFHQLYASCTLCSRRPDERLRFAVFTGAFHALSFLLSFV---VLCCT 191
+ A ++ G +L ++ + + + + FLL F+ V+
Sbjct: 162 YSGAVFYTGVNDDGLEELVSALNCVGGCQ------IIVSQGWVLIDFLLFFIPTLVMIIL 215
Query: 192 YLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFL 251
Y K+ +A+ +I+ + + S E +R ++A K + + F+
Sbjct: 216 YSKIFLIAKQQAIKIETTSSKV--------ESSSESYKIRVAKRERKAAKTLGVTVLAFV 267
Query: 252 VCFAPYVITRLVELFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKSCKEILN 310
+ + PY + L++ F ++ + AY +A +P +Y+L +RK+ K IL+
Sbjct: 268 ISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILS 326
>gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]
Length = 384
Score = 73.9 bits (180), Expect = 2e-13
Identities = 64/292 (21%), Positives = 123/292 (42%), Gaps = 19/292 (6%)
Query: 18 VSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDR 77
+ L+ N + L+ + + R P LF +L G+LL + P+ + +A R G
Sbjct: 53 IGLIGN-ITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRI 111
Query: 78 LCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMVAYTWLHALTF 137
C+L F+ S+ ++ ALS DR+ A+V P+ +A L L A+ W+ ++
Sbjct: 112 GCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLL 171
Query: 138 PAAALALSWL-GFHQLYASCTLCSRRPDERLRFAVFTGAFHALSFLLSFVVLCCTYLKVL 196
S L FH+ + T S P + + + SF+V L ++
Sbjct: 172 AIPEAVFSDLHPFHEESTNQTFISCAP-----YPHSNELHPKIHSMASFLVFYVIPLSII 226
Query: 197 KVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFLVCFAP 256
V + + + + L + ++H +++Q R+R K + F+G F C+ P
Sbjct: 227 SVYYYFIAKNLIQSAYNLPVEGNIH-------VKKQIESRKRLAKTVLVFVGLFAFCWLP 279
Query: 257 YVITRLVELFSTVPIGSHW-----GVLSKCLAYSKAASDPFVYSLLRHQYRK 303
+ L + + + + ++ LA++ + +PF LL +RK
Sbjct: 280 NHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRK 331
>gi|239757761 PREDICTED: similar to gastrin-releasing peptide
receptor [Homo sapiens]
Length = 368
Score = 73.9 bits (180), Expect = 2e-13
Identities = 64/292 (21%), Positives = 123/292 (42%), Gaps = 19/292 (6%)
Query: 18 VSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDR 77
+ L+ N + L+ + + R P LF +L G+LL + P+ + +A R G
Sbjct: 37 IGLIGN-ITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRI 95
Query: 78 LCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMVAYTWLHALTF 137
C+L F+ S+ ++ ALS DR+ A+V P+ +A L L A+ W+ ++
Sbjct: 96 GCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLL 155
Query: 138 PAAALALSWL-GFHQLYASCTLCSRRPDERLRFAVFTGAFHALSFLLSFVVLCCTYLKVL 196
S L FH+ + T S P + + + SF+V L ++
Sbjct: 156 AIPEAVFSDLHPFHEESTNQTFISCAP-----YPHSNELHPKIHSMASFLVFYVIPLSII 210
Query: 197 KVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFLVCFAP 256
V + + + + L + ++H +++Q R+R K + F+G F C+ P
Sbjct: 211 SVYYYFIAKNLIQSAYNLPVEGNIH-------VKKQIESRKRLAKTVLVFVGLFAFCWLP 263
Query: 257 YVITRLVELFSTVPIGSHW-----GVLSKCLAYSKAASDPFVYSLLRHQYRK 303
+ L + + + + ++ LA++ + +PF LL +RK
Sbjct: 264 NHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRK 315
>gi|4557861 somatostatin receptor 3 [Homo sapiens]
Length = 418
Score = 73.9 bits (180), Expect = 2e-13
Identities = 73/305 (23%), Positives = 136/305 (44%), Gaps = 42/305 (13%)
Query: 18 VSLLSNALVLLCLL-HSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGD 76
V LL N+LV+ +L H+A ++ LNL + L ++ +P A P G
Sbjct: 57 VGLLGNSLVIYVVLRHTAS--PSVTNVYILNLALADELF-MLGLPFLAAQNALSYWPFGS 113
Query: 77 RLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMVAYTWLHALT 136
+CRL +D S+ + +S+DR++AVV P R R A VA T A+
Sbjct: 114 LMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHP---TRSARWRTAP--VARTVSAAVW 168
Query: 137 FPAAALALSWLGFHQLYASCTLCSRRPDE-----RLRFAVFTGAFHALSFLLSFVVLCCT 191
+A + L + F + + C + E R F ++T AL F +V+C
Sbjct: 169 VASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTA---ALGFFGPLLVICLC 225
Query: 192 YLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFL 251
YL ++ R +R+ PS + R +R +R T+ + + F+
Sbjct: 226 YLLIVVKVRSAGRRV-------------WAPSCQRR-----RRSERRVTRMVVAVVALFV 267
Query: 252 VCFAPYVITRLVELFSTVP-----IGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKSCK 306
+C+ P+ + +V + +P G ++ V++ L Y+ + ++P +Y L +++++ +
Sbjct: 268 LCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA--LPYANSCANPILYGFLSYRFKQGFR 325
Query: 307 EILNR 311
+L R
Sbjct: 326 RVLLR 330
>gi|53828924 G protein-coupled receptor 7 [Homo sapiens]
Length = 328
Score = 71.6 bits (174), Expect = 9e-13
Identities = 72/303 (23%), Positives = 135/303 (44%), Gaps = 41/303 (13%)
Query: 18 VSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDR 77
V L N+ VL LL + ++ LF LNL + L T+V +P+ +A + ++ P G+
Sbjct: 50 VGLAGNSAVLYVLLRAPRMKT-VTNLFILNLAIADELFTLV-LPINIADFLLRQWPFGEL 107
Query: 78 LCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPL-SYRAKMRLRDAALMVAYTWLHALT 136
+C+L +D + +S+ + +S DR++ V+ S R R AA V+ +T
Sbjct: 108 MCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVT 167
Query: 137 FPAAALAL-SWLGFHQLYASCTLCSRRPDERLRFAVFTGAFHALSFLLSFVV----LCCT 191
A+ + L Q C L +P+ A + A + +L F + +C
Sbjct: 168 LVVLPFAVFARLDDEQGRRQCVLVFPQPE-----AFWWRASRLYTLVLGFAIPVSTICVL 222
Query: 192 YLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFL 251
Y +L R H R+ D H ER ++R T + + L
Sbjct: 223 YTTLL--CRLHAMRL------------DSHAKALERA-------KKRVTFLVVAILAVCL 261
Query: 252 VCFAPYVITRLVELFSTVP-----IGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKSCK 306
+C+ PY ++ +V L + +P I + + S L+Y+ + +PF+Y+ L +R++ +
Sbjct: 262 LCWTPYHLSTVVALTTDLPQTPLVIAISYFITS--LSYANSCLNPFLYAFLDASFRRNLR 319
Query: 307 EIL 309
+++
Sbjct: 320 QLI 322
>gi|30581164 neuropeptides B/W receptor 2 [Homo sapiens]
Length = 333
Score = 71.6 bits (174), Expect = 9e-13
Identities = 76/319 (23%), Positives = 137/319 (42%), Gaps = 52/319 (16%)
Query: 8 LAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGV 67
L + G V L N V+L +L + ++ +F LNL + L T+V +P+ +A
Sbjct: 48 LPAVYSGICAVGLTGNTAVILVILRAPKMKT-VTNVFILNLAVADGLFTLV-LPVNIAEH 105
Query: 68 VAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAK--MRLRDAAL 125
+ Q P G+ LC+L +D + +S+ +A +S+DR++ V+ + R R A +
Sbjct: 106 LLQYWPFGELLCKLVLAVDHYNIFSSIYFLAVMSVDRYLVVLATVRSRHMPWRTYRGAKV 165
Query: 126 MVAYTWLHALTFPAAALALSWLGFHQLYA------SCTLCSRRPDERLRFAVFTGAFHAL 179
WL L L + F +Y+ SC L P++ V+ A
Sbjct: 166 ASLCVWL-----GVTVLVLPFFSFAGVYSNELQVPSCGLSFPWPEQ-----VWFKASRVY 215
Query: 180 SFLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRA 239
+ +L FV+ CT VL DL +R L + +A
Sbjct: 216 TLVLGFVLPVCT---------------------ICVLYTDLLRRLRAVRLRSGAKALGKA 254
Query: 240 TKKISTFI----GTFLVCFAPYVITRLVELFSTVP-----IGSHWGVLSKCLAYSKAASD 290
+K++ + L+C+ P+ + +V L + +P I + + S L+Y+ + +
Sbjct: 255 RRKVTVLVLVVLAVCLLCWTPFHLASVVALTTDLPQTPLVISMSYVITS--LSYANSCLN 312
Query: 291 PFVYSLLRHQYRKSCKEIL 309
PF+Y+ L +RK+ + IL
Sbjct: 313 PFLYAFLDDNFRKNFRSIL 331
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.138 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,681,084
Number of Sequences: 37866
Number of extensions: 456530
Number of successful extensions: 2341
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 443
Number of HSP's successfully gapped in prelim test: 192
Number of HSP's that attempted gapping in prelim test: 1546
Number of HSP's gapped (non-prelim): 782
length of query: 337
length of database: 18,247,518
effective HSP length: 103
effective length of query: 234
effective length of database: 14,347,320
effective search space: 3357272880
effective search space used: 3357272880
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.