Guide to the Human Genome
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Search of human proteins with 116008440

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116008440 hypothetical protein LOC222166 [Homo sapiens]
         (131 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116008440 hypothetical protein LOC222166 [Homo sapiens]            279   5e-76
gi|169204926 PREDICTED: similar to hCG2041217 [Homo sapiens]           30   0.41 
gi|169205586 PREDICTED: similar to hCG2041217 [Homo sapiens]           30   0.41 
gi|169203873 PREDICTED: similar to REST corepressor 2 [Homo sapi...    30   0.41 
gi|115529475 polymerase (RNA) III (DNA directed) polypeptide G (...    30   0.70 
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re...    28   2.7  
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re...    28   2.7  
gi|71037379 liver glycogen phosphorylase [Homo sapiens]                28   2.7  
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]              28   2.7  
gi|6912398 general transcription factor IIIC, polypeptide 3, 102...    28   2.7  
gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]      27   3.5  
gi|90991702 leucine-rich repeat kinase 1 [Homo sapiens]                27   3.5  
gi|24797065 zinc finger protein 212 [Homo sapiens]                     27   4.6  
gi|6631095 minichromosome maintenance complex component 3 [Homo ...    27   6.0  
gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens]     27   6.0  
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ...    27   6.0  
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ...    27   6.0  
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ...    27   6.0  
gi|93204861 protein phosphatase 1, regulatory (inhibitor) subuni...    27   6.0  
gi|226693357 phospholipase A2, group IVC isoform 2 precursor [Ho...    26   7.8  
gi|226693354 phospholipase A2, group IVC isoform 1 precursor [Ho...    26   7.8  
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo...    26   7.8  

>gi|116008440 hypothetical protein LOC222166 [Homo sapiens]
          Length = 131

 Score =  279 bits (713), Expect = 5e-76
 Identities = 131/131 (100%), Positives = 131/131 (100%)

Query: 1   MDFQQLADVAEKWCSNTPFELIATEETERRMDFYADPGVSFYVLCPDNGCGDNFHVWSES 60
           MDFQQLADVAEKWCSNTPFELIATEETERRMDFYADPGVSFYVLCPDNGCGDNFHVWSES
Sbjct: 1   MDFQQLADVAEKWCSNTPFELIATEETERRMDFYADPGVSFYVLCPDNGCGDNFHVWSES 60

Query: 61  EDCLPFLQLAQDYISSCGKKTLHEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPE 120
           EDCLPFLQLAQDYISSCGKKTLHEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPE
Sbjct: 61  EDCLPFLQLAQDYISSCGKKTLHEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPE 120

Query: 121 ADHPQMGVSQQ 131
           ADHPQMGVSQQ
Sbjct: 121 ADHPQMGVSQQ 131


>gi|169204926 PREDICTED: similar to hCG2041217 [Homo sapiens]
          Length = 266

 Score = 30.4 bits (67), Expect = 0.41
 Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 1/47 (2%)

Query: 80  KTLHEVLEKVFKSFRPLLGLPDADD-DAFEEYSADVEEEEPEADHPQ 125
           K  H       +  R L G  D +D D FEE    + E EP+A HP+
Sbjct: 106 KKTHSRTSMTDRQARRLRGCKDKEDSDEFEESRGGLSEGEPDAGHPK 152


>gi|169205586 PREDICTED: similar to hCG2041217 [Homo sapiens]
          Length = 266

 Score = 30.4 bits (67), Expect = 0.41
 Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 1/47 (2%)

Query: 80  KTLHEVLEKVFKSFRPLLGLPDADD-DAFEEYSADVEEEEPEADHPQ 125
           K  H       +  R L G  D +D D FEE    + E EP+A HP+
Sbjct: 106 KKTHSRTSMTDRQARRLRGCKDKEDSDEFEESRGGLSEGEPDAGHPK 152


>gi|169203873 PREDICTED: similar to REST corepressor 2 [Homo
           sapiens]
          Length = 266

 Score = 30.4 bits (67), Expect = 0.41
 Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 1/47 (2%)

Query: 80  KTLHEVLEKVFKSFRPLLGLPDADD-DAFEEYSADVEEEEPEADHPQ 125
           K  H       +  R L G  D +D D FEE    + E EP+A HP+
Sbjct: 106 KKTHSRTSMTDRQARRLRGCKDKEDSDEFEESRGGLSEGEPDAGHPK 152


>gi|115529475 polymerase (RNA) III (DNA directed) polypeptide G
           (32kD) [Homo sapiens]
          Length = 223

 Score = 29.6 bits (65), Expect = 0.70
 Identities = 18/46 (39%), Positives = 24/46 (52%)

Query: 78  GKKTLHEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEADH 123
           G+K+  E  EK     +   G  D DDDA E+   D EE+E E D+
Sbjct: 154 GEKSDEENEEKEGSKEKSKEGDDDDDDDAAEQEEYDEEEQEEENDY 199


>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a2 isoform a [Homo sapiens]
          Length = 1590

 Score = 27.7 bits (60), Expect = 2.7
 Identities = 13/38 (34%), Positives = 21/38 (55%)

Query: 85   VLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEAD 122
            VL+ VFKS R  +   +  +D   E   + +EEE E++
Sbjct: 1494 VLQSVFKSARQKIAKEEESEDESNEEEEEEDEEESESE 1531


>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a2 isoform b [Homo sapiens]
          Length = 1572

 Score = 27.7 bits (60), Expect = 2.7
 Identities = 13/38 (34%), Positives = 21/38 (55%)

Query: 85   VLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEAD 122
            VL+ VFKS R  +   +  +D   E   + +EEE E++
Sbjct: 1476 VLQSVFKSARQKIAKEEESEDESNEEEEEEDEEESESE 1513


>gi|71037379 liver glycogen phosphorylase [Homo sapiens]
          Length = 847

 Score = 27.7 bits (60), Expect = 2.7
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 5/62 (8%)

Query: 66  FLQLAQDYISSCGKKTLHEVLE----KVFKSFRPLLGLPDADDDAFEEYSADVEE-EEPE 120
           +++  Q Y   C K+  +  LE    +  ++    LGL +A D+A  +   D+EE EE E
Sbjct: 68  WIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQLGLDIEELEEIE 127

Query: 121 AD 122
            D
Sbjct: 128 ED 129


>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
          Length = 587

 Score = 27.7 bits (60), Expect = 2.7
 Identities = 15/42 (35%), Positives = 21/42 (50%)

Query: 84  EVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEADHPQ 125
           E L++V + F     L    DD  EE   + EEEE EA+  +
Sbjct: 339 EQLQEVLEGFNMAKVLASLSDDEDEEEEEEGEEEEEEAEEEE 380



 Score = 27.3 bits (59), Expect = 3.5
 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 2/59 (3%)

Query: 67  LQLAQDYISSCGKKTLHEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEADHPQ 125
           L L  + +   G + L EVLE  F   + L  L D D+D  EE   + EEEE E +  +
Sbjct: 326 LDLNGNTLGEEGCEQLQEVLEG-FNMAKVLASLSD-DEDEEEEEEGEEEEEEAEEEEEE 382


>gi|6912398 general transcription factor IIIC, polypeptide 3, 102kDa
           [Homo sapiens]
          Length = 886

 Score = 27.7 bits (60), Expect = 2.7
 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 1/48 (2%)

Query: 80  KTLHEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEADHPQMG 127
           +T   V + V K F  +LG  + DD+  EE   + EEEE   + P  G
Sbjct: 73  ETSDGVRKSVHKVFASMLG-ENEDDEEEEEEEEEEEEEEETPEQPTAG 119


>gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]
          Length = 2539

 Score = 27.3 bits (59), Expect = 3.5
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 5/63 (7%)

Query: 63   CLPFLQLAQDYISSCGKKTLHEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEAD 122
            C P   L++D ++S    TL + L++V +S R  L LP+              ++ PEA+
Sbjct: 1068 CWP--SLSEDCVAS--HTTLSQQLDQVLQSLREALELPEPRTPPLSSLVEQAAQKAPEAE 1123

Query: 123  -HP 124
             HP
Sbjct: 1124 AHP 1126


>gi|90991702 leucine-rich repeat kinase 1 [Homo sapiens]
          Length = 2015

 Score = 27.3 bits (59), Expect = 3.5
 Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 4/51 (7%)

Query: 10   AEKWCSNTPFELI---ATEETERRMDFYADPGVSFYVLCPDNGCGDNFHVW 57
            +E W SN P  L+   A+ E  RR++ Y  P +   V+C   G G+   VW
Sbjct: 1703 SEVWYSNGPGLLVIDCASLEICRRLEPYMAPSMVTSVVCSSEGRGEEV-VW 1752


>gi|24797065 zinc finger protein 212 [Homo sapiens]
          Length = 495

 Score = 26.9 bits (58), Expect = 4.6
 Identities = 19/73 (26%), Positives = 32/73 (43%), Gaps = 2/73 (2%)

Query: 58  SESEDCLPFLQLAQDYISSCGKKTLHEVLEKVFKSFRPL--LGLPDADDDAFEEYSADVE 115
           S   D + F +   + +    K+    V+E  +++   L  LG  + + +   E   D+E
Sbjct: 142 SLENDGVCFTEQEWENLEDWQKELYRNVMESNYETLVSLKVLGQTEGEAELGTEMLGDLE 201

Query: 116 EEEPEADHPQMGV 128
           EE P   HP  GV
Sbjct: 202 EEGPGGAHPAGGV 214


>gi|6631095 minichromosome maintenance complex component 3 [Homo
           sapiens]
          Length = 808

 Score = 26.6 bits (57), Expect = 6.0
 Identities = 14/34 (41%), Positives = 21/34 (61%), Gaps = 2/34 (5%)

Query: 100 PDADD-DAFEEYS-ADVEEEEPEADHPQMGVSQQ 131
           PDA D D+++ Y  +D EEE P+   P+   SQ+
Sbjct: 697 PDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQE 730


>gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens]
          Length = 350

 Score = 26.6 bits (57), Expect = 6.0
 Identities = 10/22 (45%), Positives = 16/22 (72%)

Query: 20  ELIATEETERRMDFYADPGVSF 41
           E+I +EE ERR  FY + G+++
Sbjct: 223 EVITSEEAERRGQFYDNKGITY 244


>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
           [Homo sapiens]
          Length = 543

 Score = 26.6 bits (57), Expect = 6.0
 Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 14/44 (31%)

Query: 79  KKTLHEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEAD 122
           KKTL E ++K++K+FR               YS D E++E E +
Sbjct: 467 KKTLPEDVQKIYKTFR--------------NYSLDEEKKEEETE 496


>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
           [Homo sapiens]
          Length = 543

 Score = 26.6 bits (57), Expect = 6.0
 Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 14/44 (31%)

Query: 79  KKTLHEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEAD 122
           KKTL E ++K++K+FR               YS D E++E E +
Sbjct: 467 KKTLPEDVQKIYKTFR--------------NYSLDEEKKEEETE 496


>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
           [Homo sapiens]
          Length = 538

 Score = 26.6 bits (57), Expect = 6.0
 Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 14/44 (31%)

Query: 79  KKTLHEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEAD 122
           KKTL E ++K++K+FR               YS D E++E E +
Sbjct: 462 KKTLPEDVQKIYKTFR--------------NYSLDEEKKEEETE 491


>gi|93204861 protein phosphatase 1, regulatory (inhibitor) subunit
           9A [Homo sapiens]
          Length = 1098

 Score = 26.6 bits (57), Expect = 6.0
 Identities = 11/18 (61%), Positives = 13/18 (72%)

Query: 101 DADDDAFEEYSADVEEEE 118
           DADDD   EY+ D EE+E
Sbjct: 625 DADDDETGEYATDEEEDE 642


>gi|226693357 phospholipase A2, group IVC isoform 2 precursor [Homo
           sapiens]
          Length = 551

 Score = 26.2 bits (56), Expect = 7.8
 Identities = 22/99 (22%), Positives = 38/99 (38%), Gaps = 23/99 (23%)

Query: 28  ERRMDFYADPGVSFYVLCPDNG-------------CGDNFHVWSESEDCLPFLQLAQDY- 73
           E  +D ++    S Y+L  + G             CG +   WS++ D     +LA  Y 
Sbjct: 450 EAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIEAWSDTYDT---FKLADTYT 506

Query: 74  ------ISSCGKKTLHEVLEKVFKSFRPLLGLPDADDDA 106
                 + +  KK + E  +K+ +    + GL    D A
Sbjct: 507 LDVVVLLLALAKKNVRENKKKILRELMNVAGLYYPKDSA 545


>gi|226693354 phospholipase A2, group IVC isoform 1 precursor [Homo
           sapiens]
          Length = 541

 Score = 26.2 bits (56), Expect = 7.8
 Identities = 22/99 (22%), Positives = 38/99 (38%), Gaps = 23/99 (23%)

Query: 28  ERRMDFYADPGVSFYVLCPDNG-------------CGDNFHVWSESEDCLPFLQLAQDY- 73
           E  +D ++    S Y+L  + G             CG +   WS++ D     +LA  Y 
Sbjct: 440 EAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIEAWSDTYDT---FKLADTYT 496

Query: 74  ------ISSCGKKTLHEVLEKVFKSFRPLLGLPDADDDA 106
                 + +  KK + E  +K+ +    + GL    D A
Sbjct: 497 LDVVVLLLALAKKNVRENKKKILRELMNVAGLYYPKDSA 535


>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
            sapiens]
          Length = 1483

 Score = 26.2 bits (56), Expect = 7.8
 Identities = 11/28 (39%), Positives = 17/28 (60%)

Query: 101  DADDDAFEEYSADVEEEEPEADHPQMGV 128
            D++DD  +E   + EEEE E D+   G+
Sbjct: 1253 DSEDDESDEEEEEEEEEEEEEDYEVAGL 1280


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,694,438
Number of Sequences: 37866
Number of extensions: 241687
Number of successful extensions: 881
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 865
Number of HSP's gapped (non-prelim): 27
length of query: 131
length of database: 18,247,518
effective HSP length: 91
effective length of query: 40
effective length of database: 14,801,712
effective search space: 592068480
effective search space used: 592068480
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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