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Search of human proteins with 115529449
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115529449 upstream binding transcription factor, RNA
polymerase I isoform b [Homo sapiens]
(727 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115529449 upstream binding transcription factor, RNA polymera... 1473 0.0
gi|115529451 upstream binding transcription factor, RNA polymera... 1473 0.0
gi|7657671 upstream binding transcription factor, RNA polymerase... 1454 0.0
gi|239741668 PREDICTED: upstream binding transcription factor, R... 294 2e-79
gi|169163306 PREDICTED: upstream binding transcription factor, R... 294 2e-79
gi|239753269 PREDICTED: upstream binding transcription factor, R... 282 7e-76
gi|239741686 PREDICTED: upstream binding transcription factor, R... 282 7e-76
gi|239747816 PREDICTED: upstream binding transcription factor, R... 282 9e-76
gi|221136785 upstream binding transcription factor, RNA polymera... 280 3e-75
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 88 3e-17
gi|4504425 high-mobility group box 1 [Homo sapiens] 81 3e-15
gi|221219020 NYD-SP11 protein [Homo sapiens] 80 7e-15
gi|194688135 high-mobility group box 2 [Homo sapiens] 79 2e-14
gi|194688133 high-mobility group box 2 [Homo sapiens] 79 2e-14
gi|11321591 high-mobility group box 2 [Homo sapiens] 79 2e-14
gi|55956788 nucleolin [Homo sapiens] 78 3e-14
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 77 4e-14
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 77 4e-14
gi|239744307 PREDICTED: similar to hCG1991922 [Homo sapiens] 76 1e-13
gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens] 76 1e-13
gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens] 76 1e-13
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 75 2e-13
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 75 2e-13
gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens] 75 3e-13
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 74 4e-13
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 74 4e-13
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 74 5e-13
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 74 5e-13
gi|21735415 centromere protein B [Homo sapiens] 72 1e-12
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 72 2e-12
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 1473 bits (3813), Expect = 0.0
Identities = 727/727 (100%), Positives = 727/727 (100%)
Query: 1 MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF 60
MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF
Sbjct: 1 MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF 60
Query: 61 KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF 120
KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF
Sbjct: 61 KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF 120
Query: 121 RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR 180
RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR
Sbjct: 121 RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR 180
Query: 181 EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGI 240
EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGI
Sbjct: 181 EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGI 240
Query: 241 TKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQ 300
TKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQ
Sbjct: 241 TKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQ 300
Query: 301 KEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQ 360
KEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQ
Sbjct: 301 KEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQ 360
Query: 361 EGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYK 420
EGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYK
Sbjct: 361 EGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYK 420
Query: 421 AREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEM 480
AREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEM
Sbjct: 421 AREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEM 480
Query: 481 TWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQK 540
TWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQK
Sbjct: 481 TWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQK 540
Query: 541 FSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSL 600
FSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSL
Sbjct: 541 FSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSL 600
Query: 601 SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD 660
SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD
Sbjct: 601 SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD 660
Query: 661 ENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGD 720
ENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGD
Sbjct: 661 ENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGD 720
Query: 721 SSDSDSN 727
SSDSDSN
Sbjct: 721 SSDSDSN 727
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 1473 bits (3813), Expect = 0.0
Identities = 727/727 (100%), Positives = 727/727 (100%)
Query: 1 MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF 60
MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF
Sbjct: 1 MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF 60
Query: 61 KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF 120
KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF
Sbjct: 61 KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF 120
Query: 121 RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR 180
RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR
Sbjct: 121 RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR 180
Query: 181 EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGI 240
EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGI
Sbjct: 181 EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGI 240
Query: 241 TKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQ 300
TKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQ
Sbjct: 241 TKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQ 300
Query: 301 KEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQ 360
KEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQ
Sbjct: 301 KEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQ 360
Query: 361 EGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYK 420
EGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYK
Sbjct: 361 EGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYK 420
Query: 421 AREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEM 480
AREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEM
Sbjct: 421 AREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEM 480
Query: 481 TWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQK 540
TWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQK
Sbjct: 481 TWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQK 540
Query: 541 FSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSL 600
FSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSL
Sbjct: 541 FSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSL 600
Query: 601 SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD 660
SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD
Sbjct: 601 SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD 660
Query: 661 ENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGD 720
ENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGD
Sbjct: 661 ENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGD 720
Query: 721 SSDSDSN 727
SSDSDSN
Sbjct: 721 SSDSDSN 727
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 1454 bits (3765), Expect = 0.0
Identities = 727/764 (95%), Positives = 727/764 (95%), Gaps = 37/764 (4%)
Query: 1 MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF 60
MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF
Sbjct: 1 MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAF 60
Query: 61 KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF 120
KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF
Sbjct: 61 KDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYF 120
Query: 121 RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR 180
RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR
Sbjct: 121 RFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFR 180
Query: 181 EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPD-------------------- 220
EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPD
Sbjct: 181 EDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDK 240
Query: 221 -----------------EIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKP 263
EIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKP
Sbjct: 241 KRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKP 300
Query: 264 PPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLR 323
PPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLR
Sbjct: 301 PPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLR 360
Query: 324 FLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEE 383
FLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEE
Sbjct: 361 FLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEE 420
Query: 384 KRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGK 443
KRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGK
Sbjct: 421 KRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGK 480
Query: 444 LPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKR 503
LPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKR
Sbjct: 481 LPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKR 540
Query: 504 YERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEI 563
YERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEI
Sbjct: 541 YERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEI 600
Query: 564 GSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLR 623
GSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLR
Sbjct: 601 GSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLR 660
Query: 624 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED 683
GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED
Sbjct: 661 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED 720
Query: 684 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN
Sbjct: 721 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
>gi|239741668 PREDICTED: upstream binding transcription factor, RNA
polymerase I-like 3 [Homo sapiens]
Length = 457
Score = 294 bits (752), Expect = 2e-79
Identities = 161/370 (43%), Positives = 226/370 (61%), Gaps = 42/370 (11%)
Query: 10 DLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCK 69
D++MA P+ Q WS D+L LLECM+NNLPS+D+ F +T+SHMDW KVAFK+FSG+MC+
Sbjct: 62 DIKMALPRSQGHWSNADILRLLECMENNLPSDDNGTFSSTQSHMDWGKVAFKNFSGEMCR 121
Query: 70 LKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAK 129
LKW+EIS +RKF TL +L+L+A++ VKN K +K + HPDFPK+PLT Y RFF E +
Sbjct: 122 LKWLEISCSLRKFSTLKKLVLEAKKCVKNTNKSQKGRNHPDFPKRPLTAYIRFFKENWPQ 181
Query: 130 YAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQN 189
Y++++P M + +LTKILSKKYKELPE+ K KYIQDFQ+EKQEFE L RFRE+HPDL Q
Sbjct: 182 YSQMYPGMRSQELTKILSKKYKELPEQMKQKYIQDFQKEKQEFEEKLVRFREEHPDLDQK 241
Query: 190 AKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGITKSTLTKAE 249
KKSDI ++ +T +QK + NI E ++L K +
Sbjct: 242 GKKSDISKRIQTK------------------------VQKKVQKNIEE----VTSLPKTD 273
Query: 250 RQLKD-KFDGRPTKPPPNSYSLYCAELMAN--MKDVPSTERMVLCSQQWKLLSQKEKDAY 306
+ K KF G P KPP N Y + + ++ ++ + ERMV ++W+ + Q +KD Y
Sbjct: 274 QFFKKVKFHGEPQKPPMNGYHKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHY 333
Query: 307 HKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGG 366
+ + +K+Y+VEL +L++L E+ K++T K A GG
Sbjct: 334 KSQAELLQKEYKVELDLWLKTLSPEDYAAY-----------KESTYAKGKNMAMMGGPAP 382
Query: 367 SEKPKRPVSA 376
S K P S+
Sbjct: 383 SLKQTDPQSS 392
Score = 181 bits (459), Expect = 2e-45
Identities = 123/363 (33%), Positives = 180/363 (49%), Gaps = 57/363 (15%)
Query: 341 KMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESEL 400
K L + K+ +K + G+ + PKRP++A F +E Q + P + EL
Sbjct: 138 KKLVLEAKKCVKNTNKS---QKGRNHPDFPKRPLTAYIRFFKENWPQYSQMYPGMRSQEL 194
Query: 401 TRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVI 460
T++L++ + +L E+ K KY Q +K E EE+
Sbjct: 195 TKILSKKYKELPEQMKQKY--------IQDFQKEKQEFEEK------------------- 227
Query: 461 GDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED--QKRYERELSEMRAPPAAT 518
L RF+ + ++++K K I K + QK+ ++ + E+ + P
Sbjct: 228 ---LVRFREEHP-----------DLDQKGKKSDISKRIQTKVQKKVQKNIEEVTSLPKTD 273
Query: 519 NSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHY 578
KK+KF GEP+KPPMNGY KF Q+ S+ EL HL L+ERMVEIG RWQRI QSQK+HY
Sbjct: 274 QFFKKVKFHGEPQKPPMNGYHKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHY 333
Query: 579 KKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKS 638
K AE QK+YKV LDLW+K+LSP+D AAYKE K K+M + GP P +T QS S
Sbjct: 334 KSQAELLQKEYKVELDLWLKTLSPEDYAAYKESTYAKGKNMAMMGGPAPSLKQTDPQSSS 393
Query: 639 ES--EEDDEEDEDDEDEDEEEEDD---------ENGDSSEDGGDSSESSSEDESEDGDEN 687
+E E + + E E ++ + G+ ESS+ + G++
Sbjct: 394 AKGLQEGFGEGQGLQAAGTEASQTIWVNCQVSMEPEENRKKDGEEEESSNSLDCSSGEDM 453
Query: 688 EED 690
E D
Sbjct: 454 EVD 456
>gi|169163306 PREDICTED: upstream binding transcription factor, RNA
polymerase I-like 5 [Homo sapiens]
Length = 471
Score = 294 bits (752), Expect = 2e-79
Identities = 161/370 (43%), Positives = 226/370 (61%), Gaps = 42/370 (11%)
Query: 10 DLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCK 69
D++MA P+ Q WS D+L LLECM+NNLPS+D+ F +T+SHMDW KVAFK+FSG+MC+
Sbjct: 76 DIKMALPRSQGHWSNADILRLLECMENNLPSDDNGTFSSTQSHMDWGKVAFKNFSGEMCR 135
Query: 70 LKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAK 129
LKW+EIS +RKF TL +L+L+A++ VKN K +K + HPDFPK+PLT Y RFF E +
Sbjct: 136 LKWLEISCSLRKFSTLKKLVLEAKKCVKNTNKSQKGRNHPDFPKRPLTAYIRFFKENWPQ 195
Query: 130 YAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQN 189
Y++++P M + +LTKILSKKYKELPE+ K KYIQDFQ+EKQEFE L RFRE+HPDL Q
Sbjct: 196 YSQMYPGMRSQELTKILSKKYKELPEQMKQKYIQDFQKEKQEFEEKLVRFREEHPDLDQK 255
Query: 190 AKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGITKSTLTKAE 249
KKSDI ++ +T +QK + NI E ++L K +
Sbjct: 256 GKKSDISKRIQTK------------------------VQKKVQKNIEE----VTSLPKTD 287
Query: 250 RQLKD-KFDGRPTKPPPNSYSLYCAELMAN--MKDVPSTERMVLCSQQWKLLSQKEKDAY 306
+ K KF G P KPP N Y + + ++ ++ + ERMV ++W+ + Q +KD Y
Sbjct: 288 QFFKKVKFHGEPQKPPMNGYHKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHY 347
Query: 307 HKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGG 366
+ + +K+Y+VEL +L++L E+ K++T K A GG
Sbjct: 348 KSQAELLQKEYKVELDLWLKTLSPEDYAAY-----------KESTYAKGKNMAMMGGPAP 396
Query: 367 SEKPKRPVSA 376
S K P S+
Sbjct: 397 SLKQTDPQSS 406
Score = 181 bits (459), Expect = 2e-45
Identities = 123/363 (33%), Positives = 180/363 (49%), Gaps = 57/363 (15%)
Query: 341 KMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESEL 400
K L + K+ +K + G+ + PKRP++A F +E Q + P + EL
Sbjct: 152 KKLVLEAKKCVKNTNKS---QKGRNHPDFPKRPLTAYIRFFKENWPQYSQMYPGMRSQEL 208
Query: 401 TRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVI 460
T++L++ + +L E+ K KY Q +K E EE+
Sbjct: 209 TKILSKKYKELPEQMKQKY--------IQDFQKEKQEFEEK------------------- 241
Query: 461 GDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED--QKRYERELSEMRAPPAAT 518
L RF+ + ++++K K I K + QK+ ++ + E+ + P
Sbjct: 242 ---LVRFREEHP-----------DLDQKGKKSDISKRIQTKVQKKVQKNIEEVTSLPKTD 287
Query: 519 NSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHY 578
KK+KF GEP+KPPMNGY KF Q+ S+ EL HL L+ERMVEIG RWQRI QSQK+HY
Sbjct: 288 QFFKKVKFHGEPQKPPMNGYHKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHY 347
Query: 579 KKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKS 638
K AE QK+YKV LDLW+K+LSP+D AAYKE K K+M + GP P +T QS S
Sbjct: 348 KSQAELLQKEYKVELDLWLKTLSPEDYAAYKESTYAKGKNMAMMGGPAPSLKQTDPQSSS 407
Query: 639 ES--EEDDEEDEDDEDEDEEEEDD---------ENGDSSEDGGDSSESSSEDESEDGDEN 687
+E E + + E E ++ + G+ ESS+ + G++
Sbjct: 408 AKGLQEGFGEGQGLQAAGTEASQTIWVNCQVSMEPEENRKKDGEEEESSNSLDCSSGEDM 467
Query: 688 EED 690
E D
Sbjct: 468 EVD 470
>gi|239753269 PREDICTED: upstream binding transcription factor, RNA
polymerase I-like 6 [Homo sapiens]
Length = 400
Score = 282 bits (722), Expect = 7e-76
Identities = 156/370 (42%), Positives = 224/370 (60%), Gaps = 42/370 (11%)
Query: 10 DLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCK 69
D+++A P+ Q WS D+L LLECM+NNLP +D+ F +T+SHMDW KVAFK+FSG+MC+
Sbjct: 5 DIKVALPRSQGHWSNADILRLLECMENNLPYDDNGTFSSTQSHMDWGKVAFKNFSGEMCR 64
Query: 70 LKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAK 129
LKW+EIS +RKF TL +L+L+A++ VKN K +K + HPDFPK+ LT Y RFF E +
Sbjct: 65 LKWLEISCSLRKFSTLKKLVLEAKKCVKNTNKSQKGRNHPDFPKRLLTAYIRFFKENWPQ 124
Query: 130 YAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQN 189
Y++++P M + ++TKILSKKYKELPE+ K K+IQDF++EKQEFE LARFRE+HPDL Q
Sbjct: 125 YSQMYPGMRSQEVTKILSKKYKELPEQMKQKHIQDFRKEKQEFEEKLARFREEHPDLDQK 184
Query: 190 AKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGITKSTLTKAE 249
KKSDI ++ +T +QK + NI E +L K +
Sbjct: 185 GKKSDICKRVQTK------------------------VQKKVQKNIEE----VRSLPKTD 216
Query: 250 RQLKD-KFDGRPTKPPPNSYSLYCAELMAN--MKDVPSTERMVLCSQQWKLLSQKEKDAY 306
+ K KF G P KPP N Y + + ++ ++ + ERMV ++W+ + Q +KD Y
Sbjct: 217 QFFKKVKFHGEPQKPPMNGYQKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHY 276
Query: 307 HKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGG 366
+ + +K+Y+VEL +L++L E+ K++T K A GG
Sbjct: 277 KSQAELLQKEYKVELDLWLKTLSPEDYAAY-----------KESTYAKGKNMAMMGGPAP 325
Query: 367 SEKPKRPVSA 376
S K P S+
Sbjct: 326 SLKQTDPQSS 335
Score = 182 bits (462), Expect = 1e-45
Identities = 125/363 (34%), Positives = 182/363 (50%), Gaps = 57/363 (15%)
Query: 341 KMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESEL 400
K L + K+ +K + G+ + PKR ++A F +E Q + P + E+
Sbjct: 81 KKLVLEAKKCVKNTNKS---QKGRNHPDFPKRLLTAYIRFFKENWPQYSQMYPGMRSQEV 137
Query: 401 TRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVI 460
T++L++ + +L E+ K K+ Q RK E EE+
Sbjct: 138 TKILSKKYKELPEQMKQKH--------IQDFRKEKQEFEEK------------------- 170
Query: 461 GDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED--QKRYERELSEMRAPPAAT 518
LARF+ + ++++K K I K + QK+ ++ + E+R+ P
Sbjct: 171 ---LARFREEHP-----------DLDQKGKKSDICKRVQTKVQKKVQKNIEEVRSLPKTD 216
Query: 519 NSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHY 578
KK+KF GEP+KPPMNGYQKF Q+ S+ EL HL L+ERMVEIG RWQRI QSQK+HY
Sbjct: 217 QFFKKVKFHGEPQKPPMNGYQKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHY 276
Query: 579 KKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKS 638
K AE QK+YKV LDLW+K+LSP+D AAYKE K K+M + GP P +T QS S
Sbjct: 277 KSQAELLQKEYKVELDLWLKTLSPEDYAAYKESTYAKGKNMAMMGGPAPSLKQTDPQSSS 336
Query: 639 ES--EEDDEEDEDDEDEDEEEEDD---------ENGDSSEDGGDSSESSSEDESEDGDEN 687
+E E + + E E D+ + G+ ESS+ + G++
Sbjct: 337 AKGLQEGFGEGQGLQAAGTEASQTIWVNCQVSMEPEDNRKKDGEEEESSNSLDCSSGEDM 396
Query: 688 EED 690
E D
Sbjct: 397 EVD 399
>gi|239741686 PREDICTED: upstream binding transcription factor, RNA
polymerase I-like 6 [Homo sapiens]
Length = 400
Score = 282 bits (722), Expect = 7e-76
Identities = 156/370 (42%), Positives = 224/370 (60%), Gaps = 42/370 (11%)
Query: 10 DLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCK 69
D+++A P+ Q WS D+L LLECM+NNLP +D+ F +T+SHMDW KVAFK+FSG+MC+
Sbjct: 5 DIKVALPRSQGHWSNADILRLLECMENNLPYDDNGTFSSTQSHMDWGKVAFKNFSGEMCR 64
Query: 70 LKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAK 129
LKW+EIS +RKF TL +L+L+A++ VKN K +K + HPDFPK+ LT Y RFF E +
Sbjct: 65 LKWLEISCSLRKFSTLKKLVLEAKKCVKNTNKSQKGRNHPDFPKRLLTAYIRFFKENWPQ 124
Query: 130 YAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQN 189
Y++++P M + ++TKILSKKYKELPE+ K K+IQDF++EKQEFE LARFRE+HPDL Q
Sbjct: 125 YSQMYPGMRSQEVTKILSKKYKELPEQMKQKHIQDFRKEKQEFEEKLARFREEHPDLDQK 184
Query: 190 AKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGITKSTLTKAE 249
KKSDI ++ +T +QK + NI E +L K +
Sbjct: 185 GKKSDICKRVQTK------------------------VQKKVQKNIEE----VRSLPKTD 216
Query: 250 RQLKD-KFDGRPTKPPPNSYSLYCAELMAN--MKDVPSTERMVLCSQQWKLLSQKEKDAY 306
+ K KF G P KPP N Y + + ++ ++ + ERMV ++W+ + Q +KD Y
Sbjct: 217 QFFKKVKFHGEPQKPPMNGYQKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHY 276
Query: 307 HKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGG 366
+ + +K+Y+VEL +L++L E+ K++T K A GG
Sbjct: 277 KSQAELLQKEYKVELDLWLKTLSPEDYAAY-----------KESTYAKGKNMAMMGGPAP 325
Query: 367 SEKPKRPVSA 376
S K P S+
Sbjct: 326 SLKQTDPQSS 335
Score = 182 bits (462), Expect = 1e-45
Identities = 125/363 (34%), Positives = 182/363 (50%), Gaps = 57/363 (15%)
Query: 341 KMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESEL 400
K L + K+ +K + G+ + PKR ++A F +E Q + P + E+
Sbjct: 81 KKLVLEAKKCVKNTNKS---QKGRNHPDFPKRLLTAYIRFFKENWPQYSQMYPGMRSQEV 137
Query: 401 TRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVI 460
T++L++ + +L E+ K K+ Q RK E EE+
Sbjct: 138 TKILSKKYKELPEQMKQKH--------IQDFRKEKQEFEEK------------------- 170
Query: 461 GDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED--QKRYERELSEMRAPPAAT 518
LARF+ + ++++K K I K + QK+ ++ + E+R+ P
Sbjct: 171 ---LARFREEHP-----------DLDQKGKKSDICKRVQTKVQKKVQKNIEEVRSLPKTD 216
Query: 519 NSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHY 578
KK+KF GEP+KPPMNGYQKF Q+ S+ EL HL L+ERMVEIG RWQRI QSQK+HY
Sbjct: 217 QFFKKVKFHGEPQKPPMNGYQKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHY 276
Query: 579 KKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKS 638
K AE QK+YKV LDLW+K+LSP+D AAYKE K K+M + GP P +T QS S
Sbjct: 277 KSQAELLQKEYKVELDLWLKTLSPEDYAAYKESTYAKGKNMAMMGGPAPSLKQTDPQSSS 336
Query: 639 ES--EEDDEEDEDDEDEDEEEEDD---------ENGDSSEDGGDSSESSSEDESEDGDEN 687
+E E + + E E D+ + G+ ESS+ + G++
Sbjct: 337 AKGLQEGFGEGQGLQAAGTEASQTIWVNCQVSMEPEDNRKKDGEEEESSNSLDCSSGEDM 396
Query: 688 EED 690
E D
Sbjct: 397 EVD 399
>gi|239747816 PREDICTED: upstream binding transcription factor, RNA
polymerase I-like 6 [Homo sapiens]
Length = 400
Score = 282 bits (721), Expect = 9e-76
Identities = 156/370 (42%), Positives = 224/370 (60%), Gaps = 42/370 (11%)
Query: 10 DLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCK 69
D+++A P+ Q WS D+L LLECM+NNLP +D+ F +T+SHMDW KVAFK+FSG+MC+
Sbjct: 5 DIKVALPRSQGHWSNADILRLLECMENNLPYDDNGTFSSTQSHMDWGKVAFKNFSGEMCR 64
Query: 70 LKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAK 129
LKW+EIS +RKF TL +L+L+A++ VKN K +K + HPDFPK+ LT Y RFF E +
Sbjct: 65 LKWLEISCSLRKFSTLKKLVLEAKKCVKNTNKSQKGRNHPDFPKRLLTAYIRFFKENWPQ 124
Query: 130 YAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQN 189
Y++++P M + ++TKILSKKYKELPE+ K K+IQDF++EKQEFE LARFRE+HPDL Q
Sbjct: 125 YSQMYPGMRSQEVTKILSKKYKELPEQMKQKHIQDFRKEKQEFEEKLARFREEHPDLDQK 184
Query: 190 AKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGITKSTLTKAE 249
KKSDI ++ +T +QK + NI E +L K +
Sbjct: 185 GKKSDICKRVQTK------------------------VQKKVQKNIEE----VRSLPKTD 216
Query: 250 RQLKD-KFDGRPTKPPPNSYSLYCAELMAN--MKDVPSTERMVLCSQQWKLLSQKEKDAY 306
+ K KF G P KPP N Y + + ++ ++ + ERMV ++W+ + Q +KD Y
Sbjct: 217 QFFKKVKFHGEPQKPPMNGYHKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHY 276
Query: 307 HKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGG 366
+ + +K+Y+VEL +L++L E+ K++T K A GG
Sbjct: 277 KSQAELLQKEYKVELDLWLKTLSPEDYAAY-----------KESTYAKGKNMAMMGGPAP 325
Query: 367 SEKPKRPVSA 376
S K P S+
Sbjct: 326 SLKQTDPQSS 335
Score = 179 bits (453), Expect = 1e-44
Identities = 123/363 (33%), Positives = 181/363 (49%), Gaps = 57/363 (15%)
Query: 341 KMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESEL 400
K L + K+ +K + G+ + PKR ++A F +E Q + P + E+
Sbjct: 81 KKLVLEAKKCVKNTNKS---QKGRNHPDFPKRLLTAYIRFFKENWPQYSQMYPGMRSQEV 137
Query: 401 TRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVI 460
T++L++ + +L E+ K K+ Q RK E EE+
Sbjct: 138 TKILSKKYKELPEQMKQKH--------IQDFRKEKQEFEEK------------------- 170
Query: 461 GDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED--QKRYERELSEMRAPPAAT 518
LARF+ + ++++K K I K + QK+ ++ + E+R+ P
Sbjct: 171 ---LARFREEHP-----------DLDQKGKKSDICKRVQTKVQKKVQKNIEEVRSLPKTD 216
Query: 519 NSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHY 578
KK+KF GEP+KPPMNGY KF Q+ S+ EL HL L+ERMVEIG RWQRI QSQK+HY
Sbjct: 217 QFFKKVKFHGEPQKPPMNGYHKFHQDSWSSKELQHLSLRERMVEIGRRWQRIPQSQKDHY 276
Query: 579 KKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKS 638
K AE QK+YKV LDLW+K+LSP+D AAYKE K K+M + GP P +T QS S
Sbjct: 277 KSQAELLQKEYKVELDLWLKTLSPEDYAAYKESTYAKGKNMAMMGGPAPSLKQTDPQSSS 336
Query: 639 ES--EEDDEEDEDDEDEDEEEEDD---------ENGDSSEDGGDSSESSSEDESEDGDEN 687
+E E + + E E ++ + G+ ESS+ + G++
Sbjct: 337 AKGLQEGFGEGQGLQAAGTEASQTIWVNCQVSMEPEENRKKDGEEEESSNSLDCSSGEDM 396
Query: 688 EED 690
E D
Sbjct: 397 EVD 399
>gi|221136785 upstream binding transcription factor, RNA polymerase
I-like 1 [Homo sapiens]
Length = 393
Score = 280 bits (716), Expect = 3e-75
Identities = 155/367 (42%), Positives = 221/367 (60%), Gaps = 42/367 (11%)
Query: 13 MAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCKLKW 72
MA P+ Q WS +D+L LLECM+NN PS+D+S F +T+SHMDW KVAFK+FSG+MC+LKW
Sbjct: 1 MALPRSQGHWSNKDILRLLECMENNRPSDDNSTFSSTQSHMDWGKVAFKNFSGEMCRLKW 60
Query: 73 VEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAK 132
+EIS +RKF TL EL+L+A++ VK K +K + PDFPK+PLT Y RFF E +Y++
Sbjct: 61 LEISCNLRKFGTLKELVLEAKKCVKKMNKSQKYRNGPDFPKRPLTAYNRFFKESWPQYSQ 120
Query: 133 LHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKK 192
++P M + +LTKILSKKY+ELPE+ K KYIQDF++EKQEFE LARFRE+HPDL+Q AKK
Sbjct: 121 MYPGMRSQELTKILSKKYRELPEQMKQKYIQDFRKEKQEFEEKLARFREEHPDLVQKAKK 180
Query: 193 SDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGITKSTLTKAERQL 252
S + ++ ++ +QK + NI E +L K +R
Sbjct: 181 SSVSKR------------------------TQNKVQKKFQKNIEE----VRSLPKTDRFF 212
Query: 253 KD-KFDGRPTKPPPNSYSLYCAELMAN--MKDVPSTERMVLCSQQWKLLSQKEKDAYHKK 309
K KF G P KPP N Y + + ++ M+ + ERMV ++W+ + Q +KD + +
Sbjct: 213 KKVKFHGEPQKPPMNGYHKFHQDSWSSKEMQHLSVRERMVEIGRRWQRIPQSQKDHFKSQ 272
Query: 310 CDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEK 369
++ +K Y+V+L +L++L E K++T K A GG K
Sbjct: 273 AEELQKQYKVKLDLWLKTLSPENYAAY-----------KESTYAKGKNMAMTGGPDPRLK 321
Query: 370 PKRPVSA 376
P S+
Sbjct: 322 QADPQSS 328
Score = 187 bits (474), Expect = 4e-47
Identities = 136/415 (32%), Positives = 204/415 (49%), Gaps = 75/415 (18%)
Query: 315 KDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPV 374
K++ E+ R L+ L R G K L + K+ +K + G + PKRP+
Sbjct: 49 KNFSGEMCR-LKWLEISCNLRKFGTLKELVLEAKKCVKKMNKSQKY---RNGPDFPKRPL 104
Query: 375 SAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKP 434
+A F +E Q + P + ELT++L++ + +L E+ K KY Q RK
Sbjct: 105 TAYNRFFKESWPQYSQMYPGMRSQELTKILSKKYRELPEQMKQKY--------IQDFRKE 156
Query: 435 GGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWI 494
E EE+ LARF+ + ++ +K K +
Sbjct: 157 KQEFEEK----------------------LARFREEHP-----------DLVQKAKKSSV 183
Query: 495 KKAAED--QKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELN 552
K ++ QK++++ + E+R+ P KK+KF GEP+KPPMNGY KF Q+ S+ E+
Sbjct: 184 SKRTQNKVQKKFQKNIEEVRSLPKTDRFFKKVKFHGEPQKPPMNGYHKFHQDSWSSKEMQ 243
Query: 553 HLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYI 612
HL ++ERMVEIG RWQRI QSQK+H+K AEE QKQYKV LDLW+K+LSP++ AAYKE
Sbjct: 244 HLSVRERMVEIGRRWQRIPQSQKDHFKSQAEELQKQYKVKLDLWLKTLSPENYAAYKEST 303
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
K K+M GP+P+ + QS S + +E E G DS
Sbjct: 304 YAKGKNMAMTGGPDPRLKQADPQSSSA-------------KGLQEGFGEGQGLQAAGTDS 350
Query: 673 SES--SSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 725
S++ + S + +EN + D +++ E S+SS SSG+ + D
Sbjct: 351 SQTIWVNCHVSMEPEENRKKDREKE-------------ESSNSSDCSSGEEIEVD 392
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 87.8 bits (216), Expect = 3e-17
Identities = 152/648 (23%), Positives = 248/648 (38%), Gaps = 113/648 (17%)
Query: 93 QEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKE 152
QE K+ K KK KK DF + + + A+ K E + T+ +++
Sbjct: 35 QEPQKSKGKKKKEKKKQDFDEDDILKELEE-LSLEAQGIKADRETVAVKPTENNEEEFTS 93
Query: 153 LPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKK---------------SDIPE 197
+KKK + + +KQ F+ N + ED + K + +P+
Sbjct: 94 KDKKKKGQ-----KGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPK 148
Query: 198 KPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFD 257
K K Q K + DE I++ +N S E +S R+ + K
Sbjct: 149 KAKGKAQ----KSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKK-- 202
Query: 258 GRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDY 317
+ KP PN S N D S +K+ + +K A K+ ++KK+D
Sbjct: 203 NQKNKPGPNIES-------GNEDDDAS----------FKIKTVAQKKAEKKERERKKRDE 245
Query: 318 EVELLRFLESLPE-----------EEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGG 366
E LR L+ E +E QR EE + K + T PA E
Sbjct: 246 EKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETV----KSKVTVDTGVIPASE----- 296
Query: 367 SEKPKRPVSAMFIFS-EEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAA 425
EK + P +A ++K++ ++++ E E E EKKK KA A
Sbjct: 297 -EKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKE------------KEKKKGPSKATVKA 343
Query: 426 LKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNM 485
++ + E ++ + E KR EE+ + + L + K +R K E
Sbjct: 344 MQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQ---KEKERKER 400
Query: 486 EKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPM---NGYQKFS 542
KKE + K E + R E L ++A S + PKK P+ +K
Sbjct: 401 LKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSL-----PKKRPIYEDKKRKKIP 455
Query: 543 QELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSP 602
Q+L S + L VE+ Q + + ++ EE++ LD W S
Sbjct: 456 QQLESKEVSESMELCAA-VEVME--QGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASD 512
Query: 603 QDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDEN 662
++ + NK K NP+ EE++EE+E++EDE+ EEE++E
Sbjct: 513 EETEKVE---GNKVHIEVK---ENPE------------EEEEEEEEEEEDEESEEEEEEE 554
Query: 663 GDSSEDGGDSSESSSEDESEDG---DENEEDDEDEDDDEDDDEDEDNE 707
G+S GD + DE + G D+ + D + D D+D E
Sbjct: 555 GESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKE 602
Score = 76.3 bits (186), Expect = 1e-13
Identities = 103/531 (19%), Positives = 211/531 (39%), Gaps = 71/531 (13%)
Query: 224 RDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVP 283
R+ + P N EE +K K ++ K FD ++ ++D
Sbjct: 76 RETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSE---------------ELEDKD 120
Query: 284 STERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKML 343
S + + + D ++K + K + ++ S +E+ + + E +
Sbjct: 121 SKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRI 180
Query: 344 NINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEE---KRRQLQEERPELSESEL 400
N + + +++G K + P ++ K + + +++ E E E
Sbjct: 181 NSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERE- 239
Query: 401 TRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEE--IWQQS 458
KK+ + KA+ LK + E + G ++++ K ES ++ EE + +
Sbjct: 240 ------------RKKRDEEKAKLRKLKEKEELETG--KKDQSKQKESQRKFEEETVKSKV 285
Query: 459 VIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAAT 518
+ + ++ + A E N +KK+K KK +++K E++ +A A
Sbjct: 286 TVDTGVIPASEEKAETPTAAEDD-NEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAM 344
Query: 519 NSS-KKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEH 577
+ K+K + E +K K +EL + + +E +E R +R Q +KE
Sbjct: 345 QEALAKLKEEEERQKREEEERIKRLEELEAKRK------EEERLEQEKR-ERKKQKEKER 397
Query: 578 YKKLAEE------QQKQYKVHLDLWVKSLS------------PQDRAAYKEYISNKRKSM 619
++L +E Q++ + + +K L P+ R Y++ ++K
Sbjct: 398 KERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYED--KKRKKIP 455
Query: 620 TKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSED 679
+L S + E+ E E+ E EE+++ D+ D ++ S E
Sbjct: 456 QQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEET 515
Query: 680 ESEDGD-------ENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSD 723
E +G+ EN E++E+E+++E++DE+ + E E S S GD D
Sbjct: 516 EKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEED 566
>gi|4504425 high-mobility group box 1 [Homo sapiens]
Length = 215
Score = 81.3 bits (199), Expect = 3e-15
Identities = 58/192 (30%), Positives = 90/192 (46%), Gaps = 28/192 (14%)
Query: 482 WNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKF 541
W M KEK + A D+ RYERE+ P T KK K PK+PP + + F
Sbjct: 49 WKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETK--KKFKDPNAPKRPP-SAFFLF 105
Query: 542 SQELLSN--GELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKS 599
E GE L + + ++G W + K+ Y+K A + +++Y+
Sbjct: 106 CSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYE--------- 156
Query: 600 LSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEED 659
+D AAY+ K K P+ KS+ ++++EEDE+DE+++EEEED
Sbjct: 157 ---KDIAAYRA----KGK-------PDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEED 202
Query: 660 DENGDSSEDGGD 671
+E+ D ED D
Sbjct: 203 EEDEDEEEDDDD 214
Score = 69.7 bits (169), Expect = 9e-12
Identities = 55/194 (28%), Positives = 96/194 (49%), Gaps = 27/194 (13%)
Query: 363 GKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSE--SELTRLLARMWNDLSEKKKAKYK 420
GKG +KP+ +S+ F + R + +++ P+ S SE ++ + W +S K+K K++
Sbjct: 2 GKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFE 61
Query: 421 AREAALKAQSERK------PGGEREERGKLPESPKRAEEI-------WQQSVIGDYLARF 467
A KA+ ER+ P GE +++ K P +PKR ++ + G++
Sbjct: 62 DMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLS 121
Query: 468 KNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRA---PPAA------T 518
D K L M WNN +K + KKAA+ +++YE++++ RA P AA
Sbjct: 122 IGDVAKKLGEM---WNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKA 178
Query: 519 NSSKKMKFQGEPKK 532
SKK K + E ++
Sbjct: 179 EKSKKKKEEEEDEE 192
Score = 65.5 bits (158), Expect = 2e-10
Identities = 47/172 (27%), Positives = 73/172 (42%), Gaps = 38/172 (22%)
Query: 291 CSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 350
CS++WK +S KEK + K YE E+ ++ E KK+
Sbjct: 45 CSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGE---------------TKKKF 89
Query: 351 TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWND 410
P + PKRP SA F+F E R +++ E P LS ++ + L MWN+
Sbjct: 90 KDPNA--------------PKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNN 135
Query: 411 LSEKKKAKYKAREAALKAQSER---------KPGGEREERGKLPESPKRAEE 453
+ K Y+ + A LK + E+ KP ++ K +S K+ EE
Sbjct: 136 TAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEE 187
Score = 50.1 bits (118), Expect = 7e-06
Identities = 46/155 (29%), Positives = 72/155 (46%), Gaps = 12/155 (7%)
Query: 58 VAFKDFSGDMCKLKWVEIS-NEVRKFRTLTELILDAQEHVKNPY---KG--KKLKKHPDF 111
V F +FS C +W +S E KF + + E Y KG KK K P+
Sbjct: 36 VNFSEFS-KKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNA 94
Query: 112 PKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQE 171
PK+P + +F F E R K HP +S D+ K L + + K Y + + K++
Sbjct: 95 PKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEK 154
Query: 172 FERNLARFR-EDHPDLIQNAKKSDI-PEKPKTPQQ 204
+E+++A +R + PD AKK + EK K ++
Sbjct: 155 YEKDIAAYRAKGKPDA---AKKGVVKAEKSKKKKE 186
Score = 43.1 bits (100), Expect = 0.001
Identities = 45/220 (20%), Positives = 98/220 (44%), Gaps = 21/220 (9%)
Query: 106 KKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSN--LDLTKILSKKYKELPEKKKMKYIQ 163
K P P+ ++ Y F R ++ K HP+ S + +K S+++K + K+K K+
Sbjct: 3 KGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFED 62
Query: 164 DFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVR---PD 220
+ +K +ER + + P + KK P PK P ++ + K++ P
Sbjct: 63 MAKADKARYEREMKTYI---PPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPG 119
Query: 221 EIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMK 280
+ D +K E+ + K K +LK+K++ + Y A+ +
Sbjct: 120 LSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYE--------KDIAAYRAKGKPD-- 169
Query: 281 DVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVE 320
+ ++ V+ +++ K ++E+D ++ +++++D E E
Sbjct: 170 ---AAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDE 206
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 80.1 bits (196), Expect = 7e-15
Identities = 140/716 (19%), Positives = 295/716 (41%), Gaps = 102/716 (14%)
Query: 92 AQEHVKNPYKGKKLKKHPDF---PKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSK 148
AQ+ +G+KL + + +K L + + K AK +++ ++ IL++
Sbjct: 1638 AQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLA--EVKNILAQ 1695
Query: 149 KYKELP---------EKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKP 199
K +ELP EK+ + +++ + + +E ++ L++ KK E+
Sbjct: 1696 KVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEA 1755
Query: 200 KTPQQLWYTHEK-----KVYLKVRPDEIMRDYIQKHPELNISEEGITKSTLTKAERQLK- 253
Q+ + E+ + L ++ E + + +K PE EE + + E+++K
Sbjct: 1756 LAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPE---EEERLGRKREQLIEKKMKL 1812
Query: 254 ----DKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKK 309
+++ + N LY + +A K + E+ L ++ LL KE+ + KK
Sbjct: 1813 AQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKK 1872
Query: 310 CDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEK 369
+ K+ +L F + L + E++ L +EK I KK+ + KK Q ++
Sbjct: 1873 QLVQVKN---KLGMFNKILAQVEEK--LTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQ 1927
Query: 370 PKRPVSAMFIFSEEKRRQLQEE-RPELSESELTRLLARMWNDLSEKKKAKYKAREAALKA 428
K M + E+ Q ++ R EL ++ + L L+E+K + +E K
Sbjct: 1928 EKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSK- 1986
Query: 429 QSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNME-- 486
GE E + + + +E++++ + + DR+ A++ E+ +E
Sbjct: 1987 -------GETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFT 2039
Query: 487 --KKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKM---------KFQGEPKKPPM 535
++ + +K A+ ++ ++ + PA N K K E K
Sbjct: 2040 RGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTK 2099
Query: 536 NGYQKFSQELLSNGELNHLPLKE-----RMVEIGSRWQRISQSQKE----------HYKK 580
F +E + E + L +KE + E+ +++++ Q++ +K
Sbjct: 2100 MKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEK 2159
Query: 581 LAEEQQKQYKVHLDLWVKSLSPQDRAAYKE-----YISNK-RKSMTKLRGPNPKSSRTTL 634
+ EE+ K + H ++ L ++ +E ++ + RK RG PK ++
Sbjct: 2160 MTEEESKLARKHSEV---ILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQ 2216
Query: 635 QSKSESEE---------------------DDEEDEDDEDEDEEE---EDDENGDSSEDGG 670
+ ESEE ++EE+ ++E+E EEE E++E E+G
Sbjct: 2217 VDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGE 2276
Query: 671 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726
+ E+E + + ++ +E ++ +E +E E+ SE + S S + +S S
Sbjct: 2277 EKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCS 2332
Score = 77.4 bits (189), Expect = 4e-14
Identities = 144/715 (20%), Positives = 279/715 (39%), Gaps = 91/715 (12%)
Query: 37 NLPSNDSSKFKTTESHMDWEKVAF----KDFSGDMCKLKWVEISNEVRKFRTLTELILDA 92
N+ + + E ++DW++ ++ DM +L W E + + + E A
Sbjct: 1691 NILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLA 1750
Query: 93 QEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKE 152
+E ++ +KL + + L ++++ K A+ +M + + L +K ++
Sbjct: 1751 EEEEALAWQREKLSEE----ETKLAQEEELLIQEKEKLAQHKEKMPEEE--ERLGRKREQ 1804
Query: 153 LPEKKKMKYIQDFQR---EKQEFERN-LARFREDHPDLIQNAKKSDIPEKPKTPQQ---L 205
L EKK MK Q +R +E +N + +++ + + KK+ EK K Q+ L
Sbjct: 1805 LIEKK-MKLAQKRERWINSMEELTKNKMILYQKKN---LAQEKKNLAQEKEKLAQRKENL 1860
Query: 206 WY-----THEKKVYLKVRPDEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRP 260
Y TH KK ++V+ M + I E +++E K T+ K + +L
Sbjct: 1861 LYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQE---KETVIKKKEKL-------- 1909
Query: 261 TKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVE 320
AE + V + L +Q KL +K K A K Q KK E
Sbjct: 1910 ------------AETEKKLVQVEDS----LAKKQEKLAQEKMKLALEKAMVQGKKRLRGE 1953
Query: 321 LLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKP-----KRPVS 375
L E + + L EEKM + K+ S K + K +
Sbjct: 1954 LDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLE 2013
Query: 376 AMFIFSEEKRRQLQEERPELSESELTR---LLARMWNDLSEKKKAKYKAREAALKAQSER 432
+ E++ ++E + E TR + + L++ + K RE+ K ++
Sbjct: 2014 EKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKL 2073
Query: 433 KPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLM 492
+ ++ E EEI + + + ++ K W+ EK+ +L
Sbjct: 2074 NKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELT 2133
Query: 493 WI-KKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGEL 551
KK A Q++ ++ M +K+ K E K +K S+ +L + E
Sbjct: 2134 KDEKKLARKQRKLANKMRRM--------INKEEKMTEEESKLA----RKHSEVILDDEEE 2181
Query: 552 NHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEY 611
+ +E + + RW++ ++++ K K S D +E+
Sbjct: 2182 GGIEEEEVIPFLKRRWRKRKEAKRGDKPK----------------EKFSSQVDEVESEEH 2225
Query: 612 ISNKRKSMT-KLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGG 670
S + +S+ +L SS + + E E ++EE ++E+E +EEE+ E ++
Sbjct: 2226 FSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEE 2285
Query: 671 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 725
+ + E + E+ E EE E++++ ++E E E S S + D +
Sbjct: 2286 EKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDRE 2340
Score = 46.6 bits (109), Expect = 8e-05
Identities = 123/654 (18%), Positives = 263/654 (40%), Gaps = 111/654 (16%)
Query: 124 MEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQ--REKQEFERNLARFRE 181
ME+ + Y++ S + L+K + + K++ + ++ Q R+K++ + + ++
Sbjct: 1131 MEEASVYSQWSSSTSVIKLSKDVDSQEKDISKDHIALTLKRLQKIRDKRDKKATAQKLKK 1190
Query: 182 DHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVR-------------PDEIMRDYIQ 228
H + K++ + + TP + KKV ++ R RD +
Sbjct: 1191 KHK---KKGKEAKVINEETTPPVMEQPVTKKVKIQGRGASGISGRRSTAGDGSSWRDDLC 1247
Query: 229 KHPELNIS------EEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDV 282
+ L IS E + +T A+ L D+ S+ L+ E+ +K
Sbjct: 1248 RLMALRISGSQTKMSENLNAELVTFAQEMLVDRHP---------SWELF-QEICPLLK-- 1295
Query: 283 PSTERMVLCSQQWKLLSQKEKDAYHKKCDQKK---KDYEVELLRFLESLPEEEQQRVLGE 339
+++L W ++ ++K + ++ ++ + E++R E +P EE+Q
Sbjct: 1296 -KESKVLLEDLDWDVVPPEKKPIFIQEGAIREDMIQGVTQEVIRHKEVMPREEEQAQKKA 1354
Query: 340 EKMLNINKKQATSPASKKPA-QEGGK--GGSEKPKRPVSAMFIFS-EEKRRQLQEERPEL 395
ML + + Q KK E G G E K+ F S ++ R+ +Q+ER
Sbjct: 1355 RDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKER--- 1411
Query: 396 SESELTRLLARMWNDLSEKKKAKYKAREAALKAQS-----ERKPGGE---------REER 441
++ R + + D+SE+ + E +K + ER P + ++
Sbjct: 1412 KVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVH 1471
Query: 442 GKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQ 501
G+ +S K +E W++ ++ + + +A + + +++ +KL W E +
Sbjct: 1472 GETRKSWKAWKEEWEKRLLQE-----EEKLHQAGEKLSPEEEMLQEDKKLKW----EEWK 1522
Query: 502 KRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKE--R 559
+ +E LS + SK+ +++ E + +E+ GE + E R
Sbjct: 1523 QVWENMLS---------SKSKEQQYKDEEE-------VTLEEEVSREGEEKEQQVTEEQR 1566
Query: 560 MVEIGSRWQRISQSQKEHYKKLAEEQQK--QYKVHLDLWVKSLSPQDRAAYKEY--ISNK 615
++ +W RI + + KK A+E++K Q + L + L+ ++R + Y I+
Sbjct: 1567 HIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQD 1626
Query: 616 RKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDE----------DEEEEDDENGDS 665
+ M + G + T Q + ++ E+ + +EE+ + G
Sbjct: 1627 DREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKL 1686
Query: 666 SEDGGDSSESSSE----DESEDGDENEEDDEDEDDDEDDD-----EDEDNESEG 710
+E ++ E +++ D E E E E+ + D + E+E N+ EG
Sbjct: 1687 AEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEG 1740
Score = 45.4 bits (106), Expect = 2e-04
Identities = 65/329 (19%), Positives = 132/329 (40%), Gaps = 45/329 (13%)
Query: 293 QQWK-----LLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINK 347
++WK +LS K K+ Q K + EV L EEE R GEEK + +
Sbjct: 1519 EEWKQVWENMLSSKSKE------QQYKDEEEVTL--------EEEVSR-EGEEKEQQVTE 1563
Query: 348 KQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARM 407
+Q K A+ K + KR + EE++ +E + E +L + ++
Sbjct: 1564 EQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKI 1623
Query: 408 WNDLSEKKKA--KYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQ-------- 457
D E +A K+ +E L + E+ +E KL + K+ + W++
Sbjct: 1624 TQDDREMAQAEGKFAQKEETLAQRGEKL----SQEAEKLAQKRKKLAKKWEKVAREEEKL 1679
Query: 458 SVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAA 517
+ G LA KN + ++ + N++ +E K+ A++ + E ++ E+
Sbjct: 1680 AKKGGKLAEVKNILAQKVEELPQREQNLDWQE-----KELAQELEELEWDMEELSWKEEE 1734
Query: 518 TNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEH 577
N + + + K + +E LS E +E +++ + + + E
Sbjct: 1735 LNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEE 1794
Query: 578 YKKLAEEQQKQYKVHLDL------WVKSL 600
++L ++++ + + L W+ S+
Sbjct: 1795 EERLGRKREQLIEKKMKLAQKRERWINSM 1823
Score = 34.3 bits (77), Expect = 0.42
Identities = 49/214 (22%), Positives = 90/214 (42%), Gaps = 25/214 (11%)
Query: 228 QKHPELNISEE---GITKSTLTK-AERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVP 283
+KH E+ + +E GI + + +R+ + + + + P +S + + +V
Sbjct: 2169 RKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFS-------SQVDEVE 2221
Query: 284 STERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKML 343
S E + LL + EK ++++++ E E R E + EEE++R EE
Sbjct: 2222 SEEHF--SEEMESLLDELEKQESLSSEEEEEREEEEE--REEEEVREEEEERKEEEEG-- 2275
Query: 344 NINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPE-LSESELTR 402
+KQ +K +E K EK K V EEK + EE E LS+ E
Sbjct: 2276 --EEKQV-----EKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEE 2328
Query: 403 LLARMWNDLSEKKKAKYKAREAALKAQSERKPGG 436
+ ++ +K+ K ++ L+ Q + G
Sbjct: 2329 ESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRG 2362
Score = 33.9 bits (76), Expect = 0.55
Identities = 36/194 (18%), Positives = 82/194 (42%), Gaps = 24/194 (12%)
Query: 78 EVRKFRTLTELILDAQEH-----------VKNPYKGKKLKKHPDFPKKPLTPYFRFFMEK 126
E + R +E+ILD +E +K ++ +K K D PK+ + +
Sbjct: 2164 ESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESE 2223
Query: 127 RAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEF-------ERNLARF 179
++ + L+ + LS + +E E+++ + ++ + E++E E+ + +
Sbjct: 2224 EHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKE 2283
Query: 180 REDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEG 239
E+ + KK ++ EK + + EK+ + E + D ++ ++ EE
Sbjct: 2284 EEEKKKKKKEKKKEEVQEKEEVFE------EKEEIMSEEETESLSDEEEEEESCSLEEEV 2337
Query: 240 ITKSTLTKAERQLK 253
+ + K E+Q K
Sbjct: 2338 DREKEILKKEKQFK 2351
>gi|194688135 high-mobility group box 2 [Homo sapiens]
Length = 209
Score = 78.6 bits (192), Expect = 2e-14
Identities = 56/180 (31%), Positives = 87/180 (48%), Gaps = 22/180 (12%)
Query: 482 WNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKF 541
W M KEK + A D+ RY+RE+ PP KK K PK+PP + + F
Sbjct: 49 WKTMSAKEKSKFEDMAKSDKARYDREMKNY-VPPKGDKKGKK-KDPNAPKRPP-SAFFLF 105
Query: 542 SQELLSNGELNH--LPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKS 599
E + H L + + ++G W S K+ Y++ A + +++Y+
Sbjct: 106 CSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYE--------- 156
Query: 600 LSPQDRAAYKEYISNKRKSMTKLRGPN-PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEE 658
+D AAY+ K KS +GP P S+ + + E EE++EEDED+E+EDE+EE
Sbjct: 157 ---KDIAAYRA----KGKSEAGKKGPGRPTGSKKKNEPEDEEEEEEEEDEDEEEEDEDEE 209
Score = 65.5 bits (158), Expect = 2e-10
Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 34/163 (20%)
Query: 291 CSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 350
CS++WK +S KEK + K Y+ E+ ++
Sbjct: 45 CSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYV------------------------- 79
Query: 351 TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWND 410
K ++G K PKRP SA F+F E R +++ E P LS + + L MW++
Sbjct: 80 ----PPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSE 135
Query: 411 LSEKKKAKYKAREAALKAQSER-----KPGGEREERGKLPESP 448
S K K Y+ + A LK + E+ + G+ E K P P
Sbjct: 136 QSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRP 178
Score = 60.1 bits (144), Expect = 7e-09
Identities = 46/195 (23%), Positives = 94/195 (48%), Gaps = 28/195 (14%)
Query: 363 GKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSES--ELTRLLARMWNDLSEKKKAKYK 420
GKG KP+ +S+ F + R + +++ P+ S + E ++ + W +S K+K+K++
Sbjct: 2 GKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFE 61
Query: 421 AREAALKAQSERK------PGGEREERGKLPESPKRAEEIW-------QQSVIGDYLARF 467
+ KA+ +R+ P G+++ + K P +PKR + + + ++
Sbjct: 62 DMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLS 121
Query: 468 KNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRA----------PPAA 517
D K L M W+ K+K + +KAA+ +++YE++++ RA P
Sbjct: 122 IGDTAKKLGEM---WSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRP 178
Query: 518 TNSSKKMKFQGEPKK 532
T S KK + + E ++
Sbjct: 179 TGSKKKNEPEDEEEE 193
Score = 56.2 bits (134), Expect = 1e-07
Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 16/169 (9%)
Query: 50 ESHMDWEKVAFKDFSGDMCKLKWVEIS-NEVRKFRTLTELILDAQEH-VKN--PYKGKKL 105
+ H D V F +FS C +W +S E KF + + + +KN P KG K
Sbjct: 29 KKHPD-SSVNFAEFS-KKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPPKGDKK 86
Query: 106 --KKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQ 163
KK P+ PK+P + +F F E R K HP +S D K L + + E K K Y Q
Sbjct: 87 GKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQ 146
Query: 164 DFQREKQEFERNLARFR--------EDHPDLIQNAKKSDIPEKPKTPQQ 204
+ K+++E+++A +R + P +KK + PE + ++
Sbjct: 147 KAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTGSKKKNEPEDEEEEEE 195
Score = 38.9 bits (89), Expect = 0.017
Identities = 60/302 (19%), Positives = 106/302 (35%), Gaps = 104/302 (34%)
Query: 106 KKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSN--LDLTKILSKKYKELPEKKKMKYIQ 163
K P+ P+ ++ Y F R ++ K HP+ S + +K S+++K + K+K K+
Sbjct: 3 KGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF-- 60
Query: 164 DFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIM 223
++ KSD K R D M
Sbjct: 61 ------------------------EDMAKSD---------------------KARYDREM 75
Query: 224 RDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMK--- 280
++Y+ K +++ K K P K PP+++ L+C+E +K
Sbjct: 76 KNYVPP-----------------KGDKKGKKKDPNAP-KRPPSAFFLFCSEHRPKIKSEH 117
Query: 281 ---DVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVL 337
+ T + + + W S K+K Y +K + K+ YE ++ +
Sbjct: 118 PGLSIGDTAKKL--GEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAY------------- 162
Query: 338 GEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSE 397
+ + S A KK G GS+K P EE+ + E+ E E
Sbjct: 163 ---------RAKGKSEAGKK--GPGRPTGSKKKNEPED-----EEEEEEEEDEDEEEEDE 206
Query: 398 SE 399
E
Sbjct: 207 DE 208
>gi|194688133 high-mobility group box 2 [Homo sapiens]
Length = 209
Score = 78.6 bits (192), Expect = 2e-14
Identities = 56/180 (31%), Positives = 87/180 (48%), Gaps = 22/180 (12%)
Query: 482 WNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKF 541
W M KEK + A D+ RY+RE+ PP KK K PK+PP + + F
Sbjct: 49 WKTMSAKEKSKFEDMAKSDKARYDREMKNY-VPPKGDKKGKK-KDPNAPKRPP-SAFFLF 105
Query: 542 SQELLSNGELNH--LPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKS 599
E + H L + + ++G W S K+ Y++ A + +++Y+
Sbjct: 106 CSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYE--------- 156
Query: 600 LSPQDRAAYKEYISNKRKSMTKLRGPN-PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEE 658
+D AAY+ K KS +GP P S+ + + E EE++EEDED+E+EDE+EE
Sbjct: 157 ---KDIAAYRA----KGKSEAGKKGPGRPTGSKKKNEPEDEEEEEEEEDEDEEEEDEDEE 209
Score = 65.5 bits (158), Expect = 2e-10
Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 34/163 (20%)
Query: 291 CSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 350
CS++WK +S KEK + K Y+ E+ ++
Sbjct: 45 CSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYV------------------------- 79
Query: 351 TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWND 410
K ++G K PKRP SA F+F E R +++ E P LS + + L MW++
Sbjct: 80 ----PPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSE 135
Query: 411 LSEKKKAKYKAREAALKAQSER-----KPGGEREERGKLPESP 448
S K K Y+ + A LK + E+ + G+ E K P P
Sbjct: 136 QSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRP 178
Score = 60.1 bits (144), Expect = 7e-09
Identities = 46/195 (23%), Positives = 94/195 (48%), Gaps = 28/195 (14%)
Query: 363 GKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSES--ELTRLLARMWNDLSEKKKAKYK 420
GKG KP+ +S+ F + R + +++ P+ S + E ++ + W +S K+K+K++
Sbjct: 2 GKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFE 61
Query: 421 AREAALKAQSERK------PGGEREERGKLPESPKRAEEIW-------QQSVIGDYLARF 467
+ KA+ +R+ P G+++ + K P +PKR + + + ++
Sbjct: 62 DMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLS 121
Query: 468 KNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRA----------PPAA 517
D K L M W+ K+K + +KAA+ +++YE++++ RA P
Sbjct: 122 IGDTAKKLGEM---WSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRP 178
Query: 518 TNSSKKMKFQGEPKK 532
T S KK + + E ++
Sbjct: 179 TGSKKKNEPEDEEEE 193
Score = 56.2 bits (134), Expect = 1e-07
Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 16/169 (9%)
Query: 50 ESHMDWEKVAFKDFSGDMCKLKWVEIS-NEVRKFRTLTELILDAQEH-VKN--PYKGKKL 105
+ H D V F +FS C +W +S E KF + + + +KN P KG K
Sbjct: 29 KKHPD-SSVNFAEFS-KKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPPKGDKK 86
Query: 106 --KKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQ 163
KK P+ PK+P + +F F E R K HP +S D K L + + E K K Y Q
Sbjct: 87 GKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQ 146
Query: 164 DFQREKQEFERNLARFR--------EDHPDLIQNAKKSDIPEKPKTPQQ 204
+ K+++E+++A +R + P +KK + PE + ++
Sbjct: 147 KAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTGSKKKNEPEDEEEEEE 195
Score = 38.9 bits (89), Expect = 0.017
Identities = 60/302 (19%), Positives = 106/302 (35%), Gaps = 104/302 (34%)
Query: 106 KKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSN--LDLTKILSKKYKELPEKKKMKYIQ 163
K P+ P+ ++ Y F R ++ K HP+ S + +K S+++K + K+K K+
Sbjct: 3 KGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF-- 60
Query: 164 DFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIM 223
++ KSD K R D M
Sbjct: 61 ------------------------EDMAKSD---------------------KARYDREM 75
Query: 224 RDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMK--- 280
++Y+ K +++ K K P K PP+++ L+C+E +K
Sbjct: 76 KNYVPP-----------------KGDKKGKKKDPNAP-KRPPSAFFLFCSEHRPKIKSEH 117
Query: 281 ---DVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVL 337
+ T + + + W S K+K Y +K + K+ YE ++ +
Sbjct: 118 PGLSIGDTAKKL--GEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAY------------- 162
Query: 338 GEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSE 397
+ + S A KK G GS+K P EE+ + E+ E E
Sbjct: 163 ---------RAKGKSEAGKK--GPGRPTGSKKKNEPED-----EEEEEEEEDEDEEEEDE 206
Query: 398 SE 399
E
Sbjct: 207 DE 208
>gi|11321591 high-mobility group box 2 [Homo sapiens]
Length = 209
Score = 78.6 bits (192), Expect = 2e-14
Identities = 56/180 (31%), Positives = 87/180 (48%), Gaps = 22/180 (12%)
Query: 482 WNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKF 541
W M KEK + A D+ RY+RE+ PP KK K PK+PP + + F
Sbjct: 49 WKTMSAKEKSKFEDMAKSDKARYDREMKNY-VPPKGDKKGKK-KDPNAPKRPP-SAFFLF 105
Query: 542 SQELLSNGELNH--LPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKS 599
E + H L + + ++G W S K+ Y++ A + +++Y+
Sbjct: 106 CSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYE--------- 156
Query: 600 LSPQDRAAYKEYISNKRKSMTKLRGPN-PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEE 658
+D AAY+ K KS +GP P S+ + + E EE++EEDED+E+EDE+EE
Sbjct: 157 ---KDIAAYRA----KGKSEAGKKGPGRPTGSKKKNEPEDEEEEEEEEDEDEEEEDEDEE 209
Score = 65.5 bits (158), Expect = 2e-10
Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 34/163 (20%)
Query: 291 CSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 350
CS++WK +S KEK + K Y+ E+ ++
Sbjct: 45 CSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYV------------------------- 79
Query: 351 TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWND 410
K ++G K PKRP SA F+F E R +++ E P LS + + L MW++
Sbjct: 80 ----PPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSE 135
Query: 411 LSEKKKAKYKAREAALKAQSER-----KPGGEREERGKLPESP 448
S K K Y+ + A LK + E+ + G+ E K P P
Sbjct: 136 QSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRP 178
Score = 60.1 bits (144), Expect = 7e-09
Identities = 46/195 (23%), Positives = 94/195 (48%), Gaps = 28/195 (14%)
Query: 363 GKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSES--ELTRLLARMWNDLSEKKKAKYK 420
GKG KP+ +S+ F + R + +++ P+ S + E ++ + W +S K+K+K++
Sbjct: 2 GKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFE 61
Query: 421 AREAALKAQSERK------PGGEREERGKLPESPKRAEEIW-------QQSVIGDYLARF 467
+ KA+ +R+ P G+++ + K P +PKR + + + ++
Sbjct: 62 DMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLS 121
Query: 468 KNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRA----------PPAA 517
D K L M W+ K+K + +KAA+ +++YE++++ RA P
Sbjct: 122 IGDTAKKLGEM---WSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRP 178
Query: 518 TNSSKKMKFQGEPKK 532
T S KK + + E ++
Sbjct: 179 TGSKKKNEPEDEEEE 193
Score = 56.2 bits (134), Expect = 1e-07
Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 16/169 (9%)
Query: 50 ESHMDWEKVAFKDFSGDMCKLKWVEIS-NEVRKFRTLTELILDAQEH-VKN--PYKGKKL 105
+ H D V F +FS C +W +S E KF + + + +KN P KG K
Sbjct: 29 KKHPD-SSVNFAEFS-KKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPPKGDKK 86
Query: 106 --KKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQ 163
KK P+ PK+P + +F F E R K HP +S D K L + + E K K Y Q
Sbjct: 87 GKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQ 146
Query: 164 DFQREKQEFERNLARFR--------EDHPDLIQNAKKSDIPEKPKTPQQ 204
+ K+++E+++A +R + P +KK + PE + ++
Sbjct: 147 KAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTGSKKKNEPEDEEEEEE 195
Score = 38.9 bits (89), Expect = 0.017
Identities = 60/302 (19%), Positives = 106/302 (35%), Gaps = 104/302 (34%)
Query: 106 KKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSN--LDLTKILSKKYKELPEKKKMKYIQ 163
K P+ P+ ++ Y F R ++ K HP+ S + +K S+++K + K+K K+
Sbjct: 3 KGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF-- 60
Query: 164 DFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIM 223
++ KSD K R D M
Sbjct: 61 ------------------------EDMAKSD---------------------KARYDREM 75
Query: 224 RDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMK--- 280
++Y+ K +++ K K P K PP+++ L+C+E +K
Sbjct: 76 KNYVPP-----------------KGDKKGKKKDPNAP-KRPPSAFFLFCSEHRPKIKSEH 117
Query: 281 ---DVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVL 337
+ T + + + W S K+K Y +K + K+ YE ++ +
Sbjct: 118 PGLSIGDTAKKL--GEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAY------------- 162
Query: 338 GEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSE 397
+ + S A KK G GS+K P EE+ + E+ E E
Sbjct: 163 ---------RAKGKSEAGKK--GPGRPTGSKKKNEPED-----EEEEEEEEDEDEEEEDE 206
Query: 398 SE 399
E
Sbjct: 207 DE 208
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 77.8 bits (190), Expect = 3e-14
Identities = 33/90 (36%), Positives = 61/90 (67%), Gaps = 8/90 (8%)
Query: 628 KSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD--------SSESSSED 679
K++ S+ E +EDDE+DEDD+D++E++ ++E +++ G +++ +ED
Sbjct: 176 KAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAED 235
Query: 680 ESEDGDENEEDDEDEDDDEDDDEDEDNESE 709
E E+ D+ +EDD+D++DDEDDD+++D E E
Sbjct: 236 EDEEEDDEDEDDDDDEDDEDDDDEDDEEEE 265
Score = 76.6 bits (187), Expect = 7e-14
Identities = 36/94 (38%), Positives = 58/94 (61%), Gaps = 12/94 (12%)
Query: 627 PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSS--------- 677
P + + + + +EDDE+DEDDED+D++EEDD ++ E + ++
Sbjct: 172 PAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKN 231
Query: 678 --EDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709
EDE E+ D+ +EDD+D++DDED D+DED+E E
Sbjct: 232 VAEDEDEEEDDEDEDDDDDEDDED-DDDEDDEEE 264
Score = 73.9 bits (180), Expect = 5e-13
Identities = 33/97 (34%), Positives = 60/97 (61%), Gaps = 3/97 (3%)
Query: 609 KEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSED 668
K ++ K + K+ + + S+ EEDD+ +ED+ED+++E+ED++ + +
Sbjct: 116 KALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAM 175
Query: 669 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDED 705
++ +SEDE DE++EDDED+DDDE+DD +E+
Sbjct: 176 KAAAAAPASEDED---DEDDEDDEDDDDDEEDDSEEE 209
Score = 73.2 bits (178), Expect = 8e-13
Identities = 42/134 (31%), Positives = 63/134 (47%), Gaps = 34/134 (25%)
Query: 624 GPNPKSSRTTLQSKSESEEDDEEDED-DEDEDE---------------EEEDDENGDSSE 667
G N K + + +SEED+E+DED DEDEDE E+EDDE+ + E
Sbjct: 137 GKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDE 196
Query: 668 DGGDSSESSSEDESEDGDE------------------NEEDDEDEDDDEDDDEDEDNESE 709
D D E SE+E+ + +ED+E++D+DEDDD+DED+E +
Sbjct: 197 DDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDD 256
Query: 710 GSSSSSSSSGDSSD 723
+ +
Sbjct: 257 DDEDDEEEEEEEEE 270
Score = 48.5 bits (114), Expect = 2e-05
Identities = 22/55 (40%), Positives = 35/55 (63%), Gaps = 2/55 (3%)
Query: 673 SESSSEDESEDGDENEEDD--EDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 725
+++ + ED DE E+DD EDE+DDED+DEDED + +++++ S D D
Sbjct: 134 AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDED 188
Score = 48.1 bits (113), Expect = 3e-05
Identities = 18/58 (31%), Positives = 36/58 (62%)
Query: 670 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
G +++ DE ED D E++++DED+DED+DE E + ++++ +S + + D +
Sbjct: 137 GKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDED 194
Score = 47.8 bits (112), Expect = 4e-05
Identities = 22/97 (22%), Positives = 50/97 (51%), Gaps = 24/97 (24%)
Query: 614 NKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSS 673
++ ++M K+++ ED++E+EDDEDED+++++D
Sbjct: 206 SEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDED------------- 252
Query: 674 ESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEG 710
DE+++D++DE+++E+++E+ E+ G
Sbjct: 253 -----------DEDDDDEDDEEEEEEEEEEPVKEAPG 278
Score = 45.8 bits (107), Expect = 1e-04
Identities = 19/56 (33%), Positives = 37/56 (66%), Gaps = 1/56 (1%)
Query: 671 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDE-DNESEGSSSSSSSSGDSSDSD 725
+ + ED E+ D++ E+DE++D+DED+DEDE + + +++++ +S D D D
Sbjct: 136 NGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDED 191
Score = 43.5 bits (101), Expect = 7e-04
Identities = 18/58 (31%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Query: 627 PKSSRTTLQSKSESEEDDEEDEDDE--DEDEEEEDDENGDSSEDGGDSSESSSEDESE 682
P ++ + + E E+D++ED+DD+ DED+++EDDE + E+ E+ + + E
Sbjct: 226 PVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKE 283
Score = 40.0 bits (92), Expect = 0.008
Identities = 14/47 (29%), Positives = 31/47 (65%)
Query: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDES 681
+ + + +++D+ED+DDED++EEEE++E E G + ++ ++
Sbjct: 243 EDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKA 289
Score = 39.7 bits (91), Expect = 0.010
Identities = 15/50 (30%), Positives = 30/50 (60%)
Query: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE 688
+ +EDDE+D+D++DE+EEEE++E G E + + + + + +
Sbjct: 248 DDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQK 297
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 77.4 bits (189), Expect = 4e-14
Identities = 110/570 (19%), Positives = 238/570 (41%), Gaps = 73/570 (12%)
Query: 144 KILSKKYKELPEKKKMKYIQDFQREKQEF---------ERNLARFREDHPDLIQNAKKSD 194
K L ++ KEL E+K+++ ++ +E++E E+ +R++ Q + +
Sbjct: 328 KELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE 387
Query: 195 IPEKPKTPQQLWYTHEKKVYLK---VRPDEIMRDYIQKHPELNISEEGITKSTLTKAERQ 251
+K + ++ + ++++ K +R E M + ++K E +E K+ + + Q
Sbjct: 388 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQ 447
Query: 252 LKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKC- 310
+++ R K M ++ + + Q+ + Q+EK+ ++
Sbjct: 448 EEERIREREKK-------------MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 494
Query: 311 DQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKP 370
+QK+K +E E ++ E E+++++ +E+M KK K QE E+
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ--EKMREQEDQMWEQEEK 552
Query: 371 KRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQS 430
R +E++ QEER E E + + W D EK + + + RE K +
Sbjct: 553 MR--------DQEQKMWDQEERMEKKTQEQEK---KTW-DQEEKMREEERMREREKKMRE 600
Query: 431 ERKPGGEREERGKLPESP--KRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKK 488
E + E+EE+ + E ++ E++W+Q + + K + E W EK
Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQE------EKMQEQEEKMWEQEEKMWEQEEK- 653
Query: 489 EKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQK-FSQELLS 547
MW ++ +QK E +M+ +K+ Q + +K +K + QE +
Sbjct: 654 ---MWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR 710
Query: 548 NGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAA 607
+E M E + + + +E +K+ E+++K + ++W Q+
Sbjct: 711 E--------EESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW-----EQEEKM 757
Query: 608 YKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEE---EEDDENGD 664
+++ + K + R P K + E E+ E++E D++E+ +E+ G
Sbjct: 758 WEQ----EEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQ 813
Query: 665 SSEDGGDSSESSSEDESEDGDENEEDDEDE 694
+ G + ++E G E + ++E
Sbjct: 814 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEE 843
Score = 75.5 bits (184), Expect = 2e-13
Identities = 115/584 (19%), Positives = 242/584 (41%), Gaps = 78/584 (13%)
Query: 146 LSKKYKELPEKKKMKYIQ--DFQREKQEFERNLARFREDHPDLIQNAKKSDI---PEKPK 200
L KK EL EK + + + Q +E +R L R + P + N + ++ E+ +
Sbjct: 223 LKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 282
Query: 201 TPQQLWYTHEKKVYL---KVRPDE-IMRDYIQK--HPELNISEEGITKSTLTKAERQLKD 254
++ E+K++ ++R E MR+ +K E + E+ + L + E++L++
Sbjct: 283 EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQ---EKELREQEKELRE 339
Query: 255 KFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEK----DAYHKKC 310
+ + R + E M ++ + + Q+ K+ Q+E+ + ++
Sbjct: 340 QKELREQE-----------EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 388
Query: 311 DQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKP 370
+QK +D E + E L E+E+ R+ +EKM +Q +K QE K ++
Sbjct: 389 EQKMRDQEERMWEQDERLREKEE-RMREQEKMW----EQVEKMREEKKMQEQEKKTRDQE 443
Query: 371 KRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQS 430
++ I EK+ + +EE E ++ + MW EK+ + + E K
Sbjct: 444 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ-EEKEWQQQRLPEQKEKLWE 502
Query: 431 ERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEK--- 487
+ K + E+ + E + EE+W G ++ ++++ + + W EK
Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMW-----GQEKKMWRQEKMREQE--DQMWEQEEKMRD 555
Query: 488 KEKLMWI------KKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKF 541
+E+ MW KK E +K+ + +MR KKM+ +
Sbjct: 556 QEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREE-------------- 601
Query: 542 SQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLS 601
+E++ E +E+M E + + +E +K+ E+++K ++ +W +
Sbjct: 602 -EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL 660
Query: 602 PQDRAAYKEYISNKRKSMTKLRGPNPKS-SRTTLQSKSESEEDDEEDEDDEDEDEE---- 656
P+ + E+ K + K++ K + ++ K++ +E D++ E+E
Sbjct: 661 PEQKEKLWEH--EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRER 718
Query: 657 -----EEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 695
EE++ + E + E E E E ++ E+ E E+
Sbjct: 719 EKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEE 762
Score = 68.2 bits (165), Expect = 3e-11
Identities = 79/392 (20%), Positives = 166/392 (42%), Gaps = 30/392 (7%)
Query: 320 ELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFI 379
E+ R E L E+E++ EEKM +++ K QE EK R
Sbjct: 273 EMWRQEEELREQEKKIRKQEEKMWR-QEERLREQEGKMREQEEKMWRQEKRLR------- 324
Query: 380 FSEEKRRQLQEERPELSESELTRLLARMWNDLSEK---KKAKYKAREAALKAQSERKPGG 436
E+ ++L+E+ EL E + R + EK ++ K + +E + Q ER
Sbjct: 325 ---EQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 381
Query: 437 EREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKK 496
E++ R + + + E +W+Q D R K +R ++ E W E+ EK+ KK
Sbjct: 382 EKQMREQEQKMRDQEERMWEQ----DERLREKEER---MREQEKMW---EQVEKMREEKK 431
Query: 497 AAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPL 556
E +K+ + +M+ KKM+ + E + QK + + E
Sbjct: 432 MQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ-- 489
Query: 557 KERMVEIGSR-WQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNK 615
++R+ E + W++ + +E +K+ E+++K + ++W + + +E
Sbjct: 490 QQRLPEQKEKLWEQ--EKMQEQEEKIWEQEEK-IRDQEEMWGQEKKMWRQEKMREQEDQM 546
Query: 616 RKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSES 675
+ K+R K + + +++E +++ D E++ EEE + +
Sbjct: 547 WEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 606
Query: 676 SSEDESEDGDENEEDDEDEDDDEDDDEDEDNE 707
E++ ++ +E ++ E++ ++++ E E
Sbjct: 607 EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638
Score = 56.2 bits (134), Expect = 1e-07
Identities = 80/389 (20%), Positives = 156/389 (40%), Gaps = 40/389 (10%)
Query: 151 KELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHE 210
K++ ++KM+ +D E++E R+ + D + ++ KK+ EK + W E
Sbjct: 531 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERME--KKTQEQEK-----KTWDQEE 583
Query: 211 KKVYLKVRPDEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSL 270
K +R +E MR+ +K E EE + + K + Q ++K + K +
Sbjct: 584 K-----MREEERMREREKKMRE----EEEMMREQEEKMQEQ-EEKMQEQEEKMWEQEEKM 633
Query: 271 YCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPE 330
E ++ E+ +Q +L QKEK H+K +++K E E + + E
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKME 693
Query: 331 E----------EQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIF 380
+ +Q+++ EE M KK + +E + EK + M+
Sbjct: 694 KKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW-- 751
Query: 381 SEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREE 440
E++ + ++E + L ++W +++ K +E ++ Q E+ G E +
Sbjct: 752 -EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKM 810
Query: 441 RGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED 500
RG+ + + E++W Q + K E W EK E+ K ++
Sbjct: 811 RGQEEKMRGQEEKMWGQE------EKMWGQEEKMWGQEEKMWGQEEKMEE----KMQGQE 860
Query: 501 QKRYERELSEMRAPPAATNSSKKMKFQGE 529
+K E+E +KM+ Q E
Sbjct: 861 EKMREQEEKMRGQEEKMREQEEKMRGQEE 889
Score = 33.1 bits (74), Expect = 0.94
Identities = 39/208 (18%), Positives = 91/208 (43%), Gaps = 19/208 (9%)
Query: 148 KKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQ--L 205
K K+ E++K + Q+ RE++ + RE+ + + +K E+ Q+ +
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEM 750
Query: 206 WYTHEK------KVYLKVRPDEIMRDYIQKHPELNISEEGITKSTLTKAERQLKD---KF 256
W EK K++ + R E ++ + +H ++ E+ + + E +++D K
Sbjct: 751 WEQEEKMWEQEEKMWEQQRLPE-QKEKLWEHEKMQEQEK------IWEQEEKMRDQEEKM 803
Query: 257 DGRPTKPPPNSYSLYCAE-LMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKK 315
G+ K + E M ++ + + Q+ K+ Q+EK + ++K
Sbjct: 804 RGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKM 863
Query: 316 DYEVELLRFLESLPEEEQQRVLGEEKML 343
+ E +R E E+++++ G+E+ +
Sbjct: 864 REQEEKMRGQEEKMREQEEKMRGQEEKI 891
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 77.4 bits (189), Expect = 4e-14
Identities = 43/120 (35%), Positives = 66/120 (55%), Gaps = 8/120 (6%)
Query: 608 YKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGD--- 664
Y+E + +T L G + + + S +E + DEE+ED+E EDEE+EDDE+G+
Sbjct: 131 YRESVFKLLPQLTYLDGYD-REDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEE 189
Query: 665 -SSEDGGDSSESSSEDESEDGDENEE---DDEDEDDDEDDDEDEDNESEGSSSSSSSSGD 720
ED D ED+ E +E EE D+EDED+DED++E+E + E + G+
Sbjct: 190 FDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGE 249
Score = 51.2 bits (121), Expect = 3e-06
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 654 DEEEEDDENGDSSEDGGDSSESSSE--DESEDGDENEEDDE-DEDDDEDDDEDEDNESEG 710
D E+++ + D+ DG D E E DE ++ DE+ E++E DE+DDED+D + D + +
Sbjct: 149 DREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDE 208
Query: 711 SSSSSSSSG-DSSDSDSN 727
S G D D D +
Sbjct: 209 VSEEEEEFGLDEEDEDED 226
Score = 37.7 bits (86), Expect = 0.038
Identities = 14/60 (23%), Positives = 31/60 (51%)
Query: 668 DGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
DG D + + D + D +E++EDE+ ++++DED+++ E + + D +
Sbjct: 146 DGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDED 205
>gi|239744307 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 486
Score = 76.3 bits (186), Expect = 1e-13
Identities = 55/202 (27%), Positives = 91/202 (45%), Gaps = 30/202 (14%)
Query: 482 WNNMEKKEKLMWIKK-------AAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPP 534
W NM KEK + + A D+ Y+RE+ P T KK K PK+PP
Sbjct: 178 WKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETK--KKFKDPNAPKRPP 235
Query: 535 MNGYQKFSQELLS-NGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHL 593
+ FS+ GE L + ++G W + K+ Y+K + + +++Y+
Sbjct: 236 SAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKRSAKLKEKYE--- 292
Query: 594 DLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDE 653
+D AAY+ + K N + K + EE++EEDE+DE+E
Sbjct: 293 ---------KDIAAYR--------AKGKHDAANNGVVKAAKSKKKKEEEENEEDEEDEEE 335
Query: 654 DEEEEDDENGDSSEDGGDSSES 675
+++E++DE D E+ GD +S
Sbjct: 336 EKDEDEDEEDDEDEEDGDDEQS 357
Score = 55.8 bits (133), Expect = 1e-07
Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 22/142 (15%)
Query: 291 CSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 350
CS++WK +S KEK + + + E + + ++ E K I K
Sbjct: 174 CSERWKNMSAKEKGKFGRARGK------------FEDMAKADKAHYKREMKTY-IPPKGE 220
Query: 351 TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWND 410
T K P PKRP SA F++ E +++ ERP LS ++ + L MWN+
Sbjct: 221 TKKKFKDP---------NAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNN 271
Query: 411 LSEKKKAKYKAREAALKAQSER 432
+ K Y+ R A LK + E+
Sbjct: 272 TAADDKQPYEKRSAKLKEKYEK 293
Score = 45.8 bits (107), Expect = 1e-04
Identities = 42/165 (25%), Positives = 76/165 (46%), Gaps = 28/165 (16%)
Query: 392 RPELSESELTRLLARMWNDLSEKKKAKY-----------KAREAALKAQSER--KPGGER 438
R ++ SE ++ + W ++S K+K K+ KA +A K + + P GE
Sbjct: 162 RVSVNFSEFSKKCSERWKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGET 221
Query: 439 EERGKLPESPKRAEEIWQQSVIGDYLARFKNDRV-----KALKAMEMTWNNMEKKEKLMW 493
+++ K P +PKR + +Y + K +R K + WNN +K +
Sbjct: 222 KKKFKDPNAPKRPPSAFFL-YFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPY 280
Query: 494 IKKAAEDQKRYERELSEMRAP---PAATN------SSKKMKFQGE 529
K++A+ +++YE++++ RA AA N SKK K + E
Sbjct: 281 EKRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEE 325
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/136 (26%), Positives = 58/136 (42%), Gaps = 14/136 (10%)
Query: 58 VAFKDFSGDMCKLKWVEIS-NEVRKFRTLTELILDAQEHVKNPYKG------------KK 104
V F +FS C +W +S E KF D + K YK KK
Sbjct: 165 VNFSEFS-KKCSERWKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETKK 223
Query: 105 LKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQD 164
K P+ PK+P + +F +F E K P +S D+ K L + + K Y +
Sbjct: 224 KFKDPNAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKR 283
Query: 165 FQREKQEFERNLARFR 180
+ K+++E+++A +R
Sbjct: 284 SAKLKEKYEKDIAAYR 299
>gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]
Length = 879
Score = 76.3 bits (186), Expect = 1e-13
Identities = 56/189 (29%), Positives = 86/189 (45%), Gaps = 28/189 (14%)
Query: 475 LKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPP 534
LK TW + KEK + A D+ YERE+ P KK K PK+PP
Sbjct: 716 LKKCSETWKTIFAKEKGKFEDMAKADKAHYEREMKTYIPPKG--EKKKKFKDPNAPKRPP 773
Query: 535 MNGYQKFSQELLSN--GELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVH 592
+ + F E GE L + + + ++ W + + K+ Y+K A + +++YK
Sbjct: 774 L-AFFLFCSEYRPKIKGEHPGLSIDDVVKKLAGMWNNTAAADKQFYEKKAAKLKEKYK-- 830
Query: 593 LDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDED 652
+D AAY+ K K PN R KS+ ++++EEDE+DE
Sbjct: 831 ----------KDIAAYRA----KGK-------PNSAKKRVVKAEKSKKKKEEEEDEEDEQ 869
Query: 653 EDEEEEDDE 661
E+E EEDD+
Sbjct: 870 EEENEEDDD 878
Score = 61.6 bits (148), Expect = 2e-09
Identities = 98/425 (23%), Positives = 161/425 (37%), Gaps = 93/425 (21%)
Query: 67 MCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEK 126
MC K V S E R + ++D + N L+KH K
Sbjct: 492 MCFPKGVPRSQEARTESSQASDMMDTMDVENN----STLEKHSG---------------K 532
Query: 127 RAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDL 186
R K + +++ L + + K L K++ + QR ++ R L R R+ P +
Sbjct: 533 RRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRI 592
Query: 187 IQ----NAKKSDIPE--------------KPKTPQQLWYTHEKKVYLKVRPDEIMRDY-I 227
+ N K+S++P K T ++ + +KK + R EI D
Sbjct: 593 PKDENINFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKK-WFTPREFEIEGDRGA 651
Query: 228 QKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPP--------NSYSLYCAELMANM 279
K+ +L+I G T L +++KF P N+ C E
Sbjct: 652 SKNWKLSIRCGGYTLKVL------MENKFLPEPPSTRKKRILESHNNTLVDPCEEHKKKN 705
Query: 280 KD--VPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVL 337
D V +E + CS+ WK + KEK + K YE E+ ++ E+
Sbjct: 706 PDASVKFSEFLKKCSETWKTIFAKEKGKFEDMAKADKAHYEREMKTYIPPKGEK------ 759
Query: 338 GEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSE 397
KK+ P + PKRP A F+F E R +++ E P LS
Sbjct: 760 ---------KKKFKDPNA--------------PKRPPLAFFLFCSEYRPKIKGEHPGLSI 796
Query: 398 SELTRLLARMWNDLSEKKKAKYKAREAALKAQSER---------KPGGEREERGKLPESP 448
++ + LA MWN+ + K Y+ + A LK + ++ KP ++ K +S
Sbjct: 797 DDVVKKLAGMWNNTAAADKQFYEKKAAKLKEKYKKDIAAYRAKGKPNSAKKRVVKAEKSK 856
Query: 449 KRAEE 453
K+ EE
Sbjct: 857 KKKEE 861
Score = 45.1 bits (105), Expect = 2e-04
Identities = 41/154 (26%), Positives = 67/154 (43%), Gaps = 8/154 (5%)
Query: 35 KNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDM--CKLKWVEI-SNEVRKFRTLTELILD 91
K L S++++ E H A FS + C W I + E KF + +
Sbjct: 684 KRILESHNNTLVDPCEEHKKKNPDASVKFSEFLKKCSETWKTIFAKEKGKFEDMAKADKA 743
Query: 92 AQEHVKNPY---KGKKLKKH--PDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKIL 146
E Y KG+K KK P+ PK+P +F F E R K HP +S D+ K L
Sbjct: 744 HYEREMKTYIPPKGEKKKKFKDPNAPKRPPLAFFLFCSEYRPKIKGEHPGLSIDDVVKKL 803
Query: 147 SKKYKELPEKKKMKYIQDFQREKQEFERNLARFR 180
+ + K Y + + K+++++++A +R
Sbjct: 804 AGMWNNTAAADKQFYEKKAAKLKEKYKKDIAAYR 837
Score = 33.9 bits (76), Expect = 0.55
Identities = 27/166 (16%), Positives = 73/166 (43%), Gaps = 17/166 (10%)
Query: 558 ERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRK 617
E + + W+ I +K ++ +A+ + Y+ + ++ + + +K+ + KR
Sbjct: 714 EFLKKCSETWKTIFAKEKGKFEDMAKADKAHYEREMKTYIPPKG-EKKKKFKDPNAPKRP 772
Query: 618 SMT----------KLRGPNPKSSRTTLQSK------SESEEDDEEDEDDEDEDEEEEDDE 661
+ K++G +P S + K + + D + E + +E+ +
Sbjct: 773 PLAFFLFCSEYRPKIKGEHPGLSIDDVVKKLAGMWNNTAAADKQFYEKKAAKLKEKYKKD 832
Query: 662 NGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNE 707
G +S ++E + +E++EDE+D+++++ +ED++
Sbjct: 833 IAAYRAKGKPNSAKKRVVKAEKSKKKKEEEEDEEDEQEEENEEDDD 878
Score = 30.0 bits (66), Expect = 7.9
Identities = 40/211 (18%), Positives = 92/211 (43%), Gaps = 25/211 (11%)
Query: 113 KKPLTPYFRFFMEKRAKYAKLHPEMSNL--DLTKILSKKYKELPEKKKMKYIQDFQREKQ 170
K+ L + ++ ++ K +P+ S + K S+ +K + K+K K+ + +K
Sbjct: 684 KRILESHNNTLVDPCEEHKKKNPDASVKFSEFLKKCSETWKTIFAKEKGKFEDMAKADKA 743
Query: 171 EFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKH 230
+ER + + P + KK P PK P ++ + K++ + H
Sbjct: 744 HYEREMKTY---IPPKGEKKKKFKDPNAPKRPPLAFFLFCSEYRPKIKGE---------H 791
Query: 231 PELNISE-----EGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPST 285
P L+I + G+ +T A++Q +K + + + Y A+ N S
Sbjct: 792 PGLSIDDVVKKLAGMWNNT-AAADKQFYEKKAAKLKEKYKKDIAAYRAKGKPN-----SA 845
Query: 286 ERMVLCSQQWKLLSQKEKDAYHKKCDQKKKD 316
++ V+ +++ K ++E+D ++ ++ ++D
Sbjct: 846 KKRVVKAEKSKKKKEEEEDEEDEQEEENEED 876
>gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 488
Score = 75.9 bits (185), Expect = 1e-13
Identities = 57/216 (26%), Positives = 102/216 (47%), Gaps = 44/216 (20%)
Query: 482 WNNMEKKEKLMWIKK-------AAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPP 534
W NM KEK + + A D+ Y+RE+ P T KK K PK+PP
Sbjct: 178 WKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETK--KKFKDPNAPKRPP 235
Query: 535 MNGYQKFSQ-ELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHL 593
+ FS+ GE L + ++G W + K+ Y+K + + +++Y+
Sbjct: 236 SAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKRSAKLKEKYE--- 292
Query: 594 DLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQ-SKSESEEDDEEDEDDED 652
+D AAY + +G + ++ ++ +KS+ ++++EE+E+DE+
Sbjct: 293 ---------KDIAAY------------RAKGKHDAANNGVVKAAKSKKKKEEEENEEDEE 331
Query: 653 EDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE 688
++EEE+D+E+ D +D EDE EDGD+ +
Sbjct: 332 DEEEEKDEEDEDEEDD---------EDEEEDGDDEQ 358
Score = 55.8 bits (133), Expect = 1e-07
Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 22/142 (15%)
Query: 291 CSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 350
CS++WK +S KEK + + + E + + ++ E K I K
Sbjct: 174 CSERWKNMSAKEKGKFGRARGK------------FEDMAKADKAHYKREMKTY-IPPKGE 220
Query: 351 TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWND 410
T K P PKRP SA F++ E +++ ERP LS ++ + L MWN+
Sbjct: 221 TKKKFKDP---------NAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNN 271
Query: 411 LSEKKKAKYKAREAALKAQSER 432
+ K Y+ R A LK + E+
Sbjct: 272 TAADDKQPYEKRSAKLKEKYEK 293
Score = 50.1 bits (118), Expect = 7e-06
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 33/183 (18%)
Query: 566 RWQRISQSQKEHYKKLA---EEQQKQYKVHLDLWVKSLSP---QDRAAYKEYISNKRKSM 619
RW+ +S +K + + E+ K K H +K+ P + + +K+ + KR
Sbjct: 177 RWKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETKKKFKDPNAPKRPPS 236
Query: 620 T----------KLRGPNPKSSRTTLQSK-----SESEEDDEEDEDDEDEDEEEEDDEN-- 662
K++G P S + K + + DD++ + +E+ +++
Sbjct: 237 AFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKRSAKLKEKYEKDIA 296
Query: 663 -------GDSSEDGG-DSSESSSEDESEDGDENEEDDEDEDDDEDDDE--DEDNESEGSS 712
D++ +G +++S + E E+ +E+EED+E+E D+ED+DE DED E +G
Sbjct: 297 AYRAKGKHDAANNGVVKAAKSKKKKEEEENEEDEEDEEEEKDEEDEDEEDDEDEEEDGDD 356
Query: 713 SSS 715
S
Sbjct: 357 EQS 359
Score = 45.8 bits (107), Expect = 1e-04
Identities = 42/165 (25%), Positives = 76/165 (46%), Gaps = 28/165 (16%)
Query: 392 RPELSESELTRLLARMWNDLSEKKKAKY-----------KAREAALKAQSER--KPGGER 438
R ++ SE ++ + W ++S K+K K+ KA +A K + + P GE
Sbjct: 162 RVSVNFSEFSKKCSERWKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGET 221
Query: 439 EERGKLPESPKRAEEIWQQSVIGDYLARFKNDRV-----KALKAMEMTWNNMEKKEKLMW 493
+++ K P +PKR + +Y + K +R K + WNN +K +
Sbjct: 222 KKKFKDPNAPKRPPSAFFL-YFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPY 280
Query: 494 IKKAAEDQKRYERELSEMRAP---PAATN------SSKKMKFQGE 529
K++A+ +++YE++++ RA AA N SKK K + E
Sbjct: 281 EKRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEE 325
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/136 (26%), Positives = 58/136 (42%), Gaps = 14/136 (10%)
Query: 58 VAFKDFSGDMCKLKWVEIS-NEVRKFRTLTELILDAQEHVKNPYKG------------KK 104
V F +FS C +W +S E KF D + K YK KK
Sbjct: 165 VNFSEFS-KKCSERWKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETKK 223
Query: 105 LKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQD 164
K P+ PK+P + +F +F E K P +S D+ K L + + K Y +
Sbjct: 224 KFKDPNAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKR 283
Query: 165 FQREKQEFERNLARFR 180
+ K+++E+++A +R
Sbjct: 284 SAKLKEKYEKDIAAYR 299
Score = 30.4 bits (67), Expect = 6.1
Identities = 34/158 (21%), Positives = 59/158 (37%), Gaps = 34/158 (21%)
Query: 251 QLKDKF-DGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLC--------SQQWKLLSQK 301
+ K KF D K PP+++ LY +E +K ER L + W +
Sbjct: 220 ETKKKFKDPNAPKRPPSAFFLYFSEYGPKIKG----ERPGLSFGDVAKKLGEMWNNTAAD 275
Query: 302 EKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQE 361
+K Y K+ + K+ YE ++ + R G+ N +A KK +E
Sbjct: 276 DKQPYEKRSAKLKEKYEKDIAAY----------RAKGKHDAANNGVVKAAKSKKKKEEEE 325
Query: 362 GGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESE 399
+ ++ EEK + ++E + E E
Sbjct: 326 NEEDEEDE-----------EEEKDEEDEDEEDDEDEEE 352
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 75.1 bits (183), Expect = 2e-13
Identities = 34/92 (36%), Positives = 45/92 (48%)
Query: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 695
SKSES+ D + + D + + +N DSS+ S+ S S D S+ D + D
Sbjct: 627 SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNS 686
Query: 696 DDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
D D D N SE S SS SS DSSDS +
Sbjct: 687 SDSSDSSDSSNSSESSDSSDSSDSDSSDSSDS 718
Score = 72.4 bits (176), Expect = 1e-12
Identities = 32/105 (30%), Positives = 51/105 (48%)
Query: 623 RGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESE 682
+G + S + S + S+ D D D D + + D + S D DS S S + S+
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD 603
Query: 683 DGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
D ++ D + D D + + ++SE SS S S DSSDS+S+
Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648
Score = 71.6 bits (174), Expect = 2e-12
Identities = 33/110 (30%), Positives = 57/110 (51%)
Query: 618 SMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSS 677
S +K +S + SKS+S + + D D + + + N S D DSS+SSS
Sbjct: 620 SDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS 679
Query: 678 EDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
+S + ++ + + + E D + ++S+ S SS SS+ +SSDSDS+
Sbjct: 680 SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSS 729
Score = 70.5 bits (171), Expect = 5e-12
Identities = 34/115 (29%), Positives = 49/115 (42%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
SN S + S + S S+ D D D + D + S D DS
Sbjct: 1139 SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1198
Query: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
S+SS +S D ++ + + D + D + NES SS SS SS S+ SDS+
Sbjct: 1199 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSS 1253
Score = 70.1 bits (170), Expect = 7e-12
Identities = 36/118 (30%), Positives = 56/118 (47%), Gaps = 3/118 (2%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEE---DEDDEDEDEEEEDDENGDSSEDG 669
S K KS + + S+ + S+S+ D D D D D + D + S +
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNS 601
Query: 670 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
DSS+SS +S D ++ + D E D D D++S+ S S+SS S D+SDS +
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS 659
Score = 70.1 bits (170), Expect = 7e-12
Identities = 34/117 (29%), Positives = 56/117 (47%), Gaps = 2/117 (1%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE--DGG 670
SN S + S+ ++ S+S+ D D D D + ++ DSS+ D
Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSS 617
Query: 671 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
DSS+S S+ + D ++ D + + D + + DN SS+SS+S DSSDS +
Sbjct: 618 DSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS 674
Score = 68.9 bits (167), Expect = 2e-11
Identities = 36/119 (30%), Positives = 51/119 (42%), Gaps = 4/119 (3%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
SN S N S + S + S+ D D D + D + +S D DS
Sbjct: 738 SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797
Query: 673 SESS----SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
S SS S D S+ D ++ D + D + + D+ + SS SS S D SDSDS+
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS 856
Score = 67.0 bits (162), Expect = 6e-11
Identities = 36/104 (34%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
Query: 629 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS----SEDESEDG 684
SS + S D D + + + D N S D DSS SS S D S+
Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777
Query: 685 DENEEDDEDEDDDEDDDEDEDNESEGSSSSSSS-SGDSSDSDSN 727
D + D ++ + D D N S+ S+SS SS S DSSDSDS+
Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821
Score = 66.2 bits (160), Expect = 1e-10
Identities = 37/117 (31%), Positives = 51/117 (43%), Gaps = 2/117 (1%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
SN S + S + S S+ D + D + + D + S D DS
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081
Query: 673 SESS-SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSS-SSSSGDSSDSDSN 727
SESS S D S D ++ D + D D D + S+ S+SS SS S DSSDS +
Sbjct: 1082 SESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1138
Score = 66.2 bits (160), Expect = 1e-10
Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 1/115 (0%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
SN S + S + S SE D D D + + D + S D +S
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180
Query: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
S+SS +S D ++ D D D D + D+ SS SS S DSSDS+ +
Sbjct: 1181 SDSSDSSDSSDSSDSS-DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNES 1234
Score = 66.2 bits (160), Expect = 1e-10
Identities = 33/117 (28%), Positives = 50/117 (42%), Gaps = 2/117 (1%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
S+ S + S + S S+ D D D + + D + S D DS
Sbjct: 1172 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1231
Query: 673 SESSSEDESEDGDE--NEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
+ESS +S D + N D D D D D ++ES+ S S + + + SDSDS+
Sbjct: 1232 NESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSD 1288
Score = 65.5 bits (158), Expect = 2e-10
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 629 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE 688
S+ T S S ++ D++D+ + + + D + S D +SS+SS +S+ D N
Sbjct: 517 STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS 576
Query: 689 EDDEDEDD-DEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
D D D D D D D+ +SS SS S DSSDS +
Sbjct: 577 SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS 616
Score = 65.5 bits (158), Expect = 2e-10
Identities = 38/127 (29%), Positives = 52/127 (40%), Gaps = 12/127 (9%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE--DGG 670
SN S + S + S + S+ D D D D + + DSS+ +
Sbjct: 780 SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839
Query: 671 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSS----------SSSSGD 720
DSS+SS + D D + D D D D N S+ S SS SS S +
Sbjct: 840 DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN 899
Query: 721 SSDSDSN 727
SSDSDS+
Sbjct: 900 SSDSDSS 906
Score = 65.1 bits (157), Expect = 2e-10
Identities = 32/115 (27%), Positives = 47/115 (40%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
SN S + +S + S S+ D D + D + +S + DS
Sbjct: 645 SNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS 704
Query: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
S+SS D S+ D + + D D D + + S SS SS SS S SDS+
Sbjct: 705 SDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 759
Score = 65.1 bits (157), Expect = 2e-10
Identities = 37/117 (31%), Positives = 48/117 (41%), Gaps = 2/117 (1%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
SN S + S + S S+ D + D + + D + +S D DS
Sbjct: 729 SNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDS 788
Query: 673 SESS-SEDESEDGD-ENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
S SS S D S D N D D D D D ++S SS SS SS S SDS+
Sbjct: 789 SNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845
Score = 65.1 bits (157), Expect = 2e-10
Identities = 34/118 (28%), Positives = 49/118 (41%), Gaps = 3/118 (2%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGD---SSEDG 669
SN S N S + S S+ + D +D + D N +S D
Sbjct: 750 SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809
Query: 670 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
DSS+SS D S D + D + + D D + S+GS S SS+ DSS+S +
Sbjct: 810 SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867
Score = 65.1 bits (157), Expect = 2e-10
Identities = 36/116 (31%), Positives = 51/116 (43%), Gaps = 3/116 (2%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
S+ S + S + S S+ D + D + + D + +S D DS
Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDS 1147
Query: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGS-SSSSSSSGDSSDSDSN 727
SESS D S+ D ++ D + D D D N S+ S SS SS S DSSDS +
Sbjct: 1148 SESS--DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1201
Score = 64.7 bits (156), Expect = 3e-10
Identities = 32/99 (32%), Positives = 44/99 (44%), Gaps = 1/99 (1%)
Query: 630 SRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-SEDESEDGDENE 688
S + S S D D D + D + +S D DSS+SS S D S D N+
Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND 787
Query: 689 EDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
+ + D + D N S+ S SS SS DSS+S +
Sbjct: 788 SSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDS 826
Score = 64.7 bits (156), Expect = 3e-10
Identities = 31/115 (26%), Positives = 49/115 (42%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
S+ S + S + +S + S+ D + D D + ++ DSS S
Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS 924
Query: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
S+S D S D + D + D + D N S+ S+SS SS +SSDS +
Sbjct: 925 ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS 979
Score = 64.3 bits (155), Expect = 4e-10
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 640 SEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDED 699
++++D+ D D + D + +S D DSS+S S D + D + D + D +
Sbjct: 534 NDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDS 593
Query: 700 DDEDEDNESEGSSSSSSS-SGDSSDSDSN 727
D D N S+ S SS SS S DSSDS +
Sbjct: 594 DSSDSSNSSDSSDSSDSSDSSDSSDSSDS 622
Score = 64.3 bits (155), Expect = 4e-10
Identities = 27/90 (30%), Positives = 43/90 (47%)
Query: 638 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDD 697
S+S+ + D + + + D N S D DS+ESS+ +S D + + D + +
Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910
Query: 698 EDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
D D N S+ S SS+SS +S SN
Sbjct: 911 SSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940
Score = 63.9 bits (154), Expect = 5e-10
Identities = 54/245 (22%), Positives = 99/245 (40%), Gaps = 24/245 (9%)
Query: 500 DQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGE--------- 550
+ KR E +++ + T++ K + +G K P +G + ++E+ E
Sbjct: 351 ESKRVENRITK----ESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHG 406
Query: 551 ----LNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRA 606
++ + +V I Q+ K + + D KS+ D
Sbjct: 407 MILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPN 466
Query: 607 AYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDD---EDEDEEE-EDDEN 662
+ E N + N SSR S+ +D+ D ED+D + D N
Sbjct: 467 SSDESNGNDDANS---ESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNN 523
Query: 663 GDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSS 722
DS+ +G + ++ + + +S G + D + D D + ++S+ S S+SSS DSS
Sbjct: 524 SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSS 583
Query: 723 DSDSN 727
DSDS+
Sbjct: 584 DSDSS 588
Score = 63.9 bits (154), Expect = 5e-10
Identities = 36/114 (31%), Positives = 50/114 (43%), Gaps = 15/114 (13%)
Query: 629 SSRTTLQSKSESEEDDEEDEDDE--DEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDE 686
+S + S S+ D D D D + E D + DS D DS+ S S D S+ D
Sbjct: 600 NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS 659
Query: 687 NEEDDEDEDDDEDDDEDEDNESEGSSSS-------------SSSSGDSSDSDSN 727
+ + + D D D + S+ S+SS SS S DSSDSDS+
Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS 713
Score = 63.5 bits (153), Expect = 6e-10
Identities = 31/115 (26%), Positives = 46/115 (40%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
SN S + S + S S D D + + D + S D S
Sbjct: 762 SNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821
Query: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
+ S S + S+ D + D + D D D D+ + SS+SS S DSSDS ++
Sbjct: 822 NSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876
Score = 63.2 bits (152), Expect = 8e-10
Identities = 28/102 (27%), Positives = 46/102 (45%)
Query: 626 NPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGD 685
N S + S S+ D D D D + + DSS+ S+ S S D S+ +
Sbjct: 828 NSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNE 887
Query: 686 ENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
+ D + + D + D+ + SS SS+S DSS+S ++
Sbjct: 888 SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929
Score = 62.8 bits (151), Expect = 1e-09
Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 1/115 (0%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
S+ S + + S + S D D D + + ++ DSS+ DS
Sbjct: 567 SDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDS 626
Query: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
S+S S D S+ +++ D + D D+ + D+ + +SS SS S DSSDS S+
Sbjct: 627 SKSES-DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680
Score = 62.8 bits (151), Expect = 1e-09
Identities = 31/100 (31%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
Query: 629 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE-DGGDSSESSSEDESEDGDEN 687
SS ++ S S + + D D E ++ DSS+ D DSS+SS+ + S+ N
Sbjct: 671 SSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSN 730
Query: 688 EEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
D D + D + D+ + SS SS S +SSDS +
Sbjct: 731 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770
Score = 62.8 bits (151), Expect = 1e-09
Identities = 34/120 (28%), Positives = 52/120 (43%), Gaps = 5/120 (4%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGG-- 670
S+ S + N S + S + SE D D D D + + + S D
Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 731
Query: 671 -DSSESSSEDESEDGDE--NEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
DSS+SS+ +S D + N D D D + + D+ SS SS+S DS+DS ++
Sbjct: 732 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNS 791
Score = 62.4 bits (150), Expect = 1e-09
Identities = 29/102 (28%), Positives = 49/102 (48%)
Query: 626 NPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGD 685
N S+ S+S D + + + + +D++ DS + DSS+S S D S D
Sbjct: 503 NGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSD 562
Query: 686 ENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
++ D D D + + ++S+ S SS S S DSS+S +
Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDS 604
Score = 62.4 bits (150), Expect = 1e-09
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 7/122 (5%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
SN + SS + S S + + + + D + D DSS+ DS
Sbjct: 574 SNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDS 633
Query: 673 SESSSEDESEDGDENEEDDEDEDDD-------EDDDEDEDNESEGSSSSSSSSGDSSDSD 725
S+S S+ +S D + ++ D + D D + D+ SSS SS+S DSSDS
Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693
Query: 726 SN 727
+
Sbjct: 694 DS 695
Score = 62.0 bits (149), Expect = 2e-09
Identities = 31/115 (26%), Positives = 50/115 (43%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
SN S + + SS ++ S S + ++ + D + ++ DSS S
Sbjct: 898 SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957
Query: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
+ S S + S+ D N D D + D + D+ SS SS+S DSSDS +
Sbjct: 958 NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1012
Score = 61.2 bits (147), Expect = 3e-09
Identities = 33/128 (25%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
Query: 601 SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD 660
S + A+Y S + + +G S +T + + + + +D+++ +
Sbjct: 486 SSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKG 545
Query: 661 ENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSS-SG 719
++ S D DSS SS +S D D ++ + + D D D + ++S+ S SS+SS S
Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSS 605
Query: 720 DSSDSDSN 727
DSSDS +
Sbjct: 606 DSSDSSDS 613
Score = 61.2 bits (147), Expect = 3e-09
Identities = 34/101 (33%), Positives = 44/101 (43%), Gaps = 12/101 (11%)
Query: 637 KSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDD 696
KS+S + + D + D D + S D DS+ SS D S D D ++ D D D
Sbjct: 539 KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSD-SSDSDSSDSSDSDSSD 597
Query: 697 -----------DEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726
D D D + S+ S SS S DSSDSDS
Sbjct: 598 SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS 638
Score = 61.2 bits (147), Expect = 3e-09
Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 2/116 (1%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
S+ S G + SS + S S D + + D + + +E+ +SS D DS
Sbjct: 839 SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS-DSSDS 897
Query: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDE-DNESEGSSSSSSSSGDSSDSDSN 727
S SS D S+ + ++ D D + + DN + SS+SS S DSSDS ++
Sbjct: 898 SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953
Score = 61.2 bits (147), Expect = 3e-09
Identities = 33/101 (32%), Positives = 51/101 (50%), Gaps = 9/101 (8%)
Query: 629 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE--DGGDSSESSSEDESEDGDE 686
SS ++ S S D + D D + + +E+ DSS+ D DSS SS +S D +
Sbjct: 1201 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSD 1260
Query: 687 NEEDDEDEDDDE-------DDDEDEDNESEGSSSSSSSSGD 720
+ D DE D + ++ D D++SEGS S+ S+S D
Sbjct: 1261 STSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 60.8 bits (146), Expect = 4e-09
Identities = 35/118 (29%), Positives = 52/118 (44%), Gaps = 3/118 (2%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
SN S + S + S S+ D D D + + D + S + DS
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237
Query: 673 SESS-SEDESEDGDENE-EDDEDEDDDEDDDEDEDNES-EGSSSSSSSSGDSSDSDSN 727
S+SS S D S D ++ D D D +D+ D ++S G+++ S S DS SDSN
Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSN 1295
Score = 60.5 bits (145), Expect = 5e-09
Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 1/116 (0%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
S+ S + +S + S S+ D + D ++ D + +S D +S
Sbjct: 747 SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS 806
Query: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSD-SDSN 727
S+SS +S D D + D D D + + S+ S SS S DSS+ SDS+
Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSS 862
Score = 58.5 bits (140), Expect = 2e-08
Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 11/126 (8%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
S+ + + + + + S + S D D D + D N S D DS
Sbjct: 636 SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS 695
Query: 673 SESSSEDESEDGDENEEDDEDE-------DDDEDDDEDEDNESEGSSSS----SSSSGDS 721
S SS +S D +++ D + D D + D + S S SS SS+S DS
Sbjct: 696 SNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDS 755
Query: 722 SDSDSN 727
SDS +
Sbjct: 756 SDSSDS 761
Score = 58.2 bits (139), Expect = 3e-08
Identities = 29/129 (22%), Positives = 54/129 (41%)
Query: 599 SLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEE 658
S S D + + + S + + SS + S+S + D D + + +
Sbjct: 677 SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736
Query: 659 DDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 718
+ DSS+ S+ S S D S+ + ++ D + D D + + ++ S+SS SS
Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSD 796
Query: 719 GDSSDSDSN 727
+S SN
Sbjct: 797 SSNSSDSSN 805
Score = 48.1 bits (113), Expect = 3e-05
Identities = 23/92 (25%), Positives = 41/92 (44%)
Query: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 695
S S + D++EDE D+++EE + S+ G + +++ D + D E
Sbjct: 245 SPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEY 304
Query: 696 DDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
D + ED NE +G +S S + + N
Sbjct: 305 YDPEGKEDPHNEVDGDKTSKSEENSAGIPEDN 336
Score = 44.3 bits (103), Expect = 4e-04
Identities = 28/121 (23%), Positives = 50/121 (41%), Gaps = 10/121 (8%)
Query: 614 NKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDE----------DEEEEDDENG 663
N+ ++ + GP S + ++ E E+ +E + E +E + G
Sbjct: 173 NEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPG 232
Query: 664 DSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSD 723
+ G D+S+ S D DE+E +DED++ + +D N S+G D D
Sbjct: 233 TGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHD 292
Query: 724 S 724
S
Sbjct: 293 S 293
Score = 40.0 bits (92), Expect = 0.008
Identities = 19/79 (24%), Positives = 30/79 (37%)
Query: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 672
S+ S + S + S + S+ D D D D +E D S +
Sbjct: 1223 SDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNG 1282
Query: 673 SESSSEDESEDGDENEEDD 691
S+S S+ E D + + DD
Sbjct: 1283 SDSDSDSEGSDSNHSTSDD 1301
Score = 35.8 bits (81), Expect = 0.14
Identities = 25/96 (26%), Positives = 38/96 (39%), Gaps = 4/96 (4%)
Query: 629 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE 688
+S T Q S+ E + ++ D+ +G S +G D EDE DE+E
Sbjct: 210 TSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGAD----EDEDEGSGDDEDE 265
Query: 689 EDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDS 724
E +D + E + SS G +SDS
Sbjct: 266 EAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDS 301
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 75.1 bits (183), Expect = 2e-13
Identities = 40/108 (37%), Positives = 64/108 (59%), Gaps = 3/108 (2%)
Query: 605 RAAYKEYISNKRKSMTKL-RGPNPKSSRTTLQSKSES--EEDDEEDEDDEDEDEEEEDDE 661
R+ Y ++ KRK+ K + P PK +++ S S E DD + +D DE EE+E +E
Sbjct: 50 RSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE 109
Query: 662 NGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709
+ +++ GD E E + E+ +E EE+DED+D+D +D EDE+ E E
Sbjct: 110 YSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEE 157
Score = 68.9 bits (167), Expect = 2e-11
Identities = 30/94 (31%), Positives = 60/94 (63%), Gaps = 3/94 (3%)
Query: 634 LQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 693
+ K E E ++ +++DE DE+EED+E GD E+ + E ED+ EDG++ E+++E+
Sbjct: 99 MDEKEEDEGEEYSEDNDEPGDEDEEDEE-GDREEE--EEIEEEDEDDDEDGEDVEDEEEE 155
Query: 694 EDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
E+++E+++E+E+NE + ++ ++ D N
Sbjct: 156 EEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDN 189
Score = 58.9 bits (141), Expect = 2e-08
Identities = 40/126 (31%), Positives = 62/126 (49%), Gaps = 41/126 (32%)
Query: 641 EEDDEEDEDDEDEDEE-EEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED------ 693
+ED+E++E D +E+EE EE+DE D EDG D + E+E E+ +E EE++ED
Sbjct: 119 DEDEEDEEGDREEEEEIEEEDE--DDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCH 176
Query: 694 --------EDDDEDDDEDED------------------------NESEGSSSSSSSSGDS 721
E DD ++DE ++ ESE +S++S+S D
Sbjct: 177 NTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDD 236
Query: 722 SDSDSN 727
SD + N
Sbjct: 237 SDKNEN 242
>gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 487
Score = 74.7 bits (182), Expect = 3e-13
Identities = 54/202 (26%), Positives = 91/202 (45%), Gaps = 29/202 (14%)
Query: 482 WNNMEKKEKLMWIKK-------AAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPP 534
W NM KEK + + A D+ Y+RE+ P T KK K PK+PP
Sbjct: 178 WKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETK--KKFKDPNAPKRPP 235
Query: 535 MNGYQKFSQELLS-NGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHL 593
+ FS+ GE L + ++G W + K+ Y+K + + +++Y+
Sbjct: 236 SAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKRSAKLKEKYE--- 292
Query: 594 DLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDE 653
+D AAY+ + + ++ K K E EE++E++ED+E+E
Sbjct: 293 ---------KDIAAYRAKGKHDAANNGVVKAAKSKK-------KKEEEENEEDEEDEEEE 336
Query: 654 DEEEEDDENGDSSEDGGDSSES 675
+EE++DE D E+ GD +S
Sbjct: 337 KDEEDEDEEDDEDEEDGDDEQS 358
Score = 55.8 bits (133), Expect = 1e-07
Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 22/142 (15%)
Query: 291 CSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA 350
CS++WK +S KEK + + + E + + ++ E K I K
Sbjct: 174 CSERWKNMSAKEKGKFGRARGK------------FEDMAKADKAHYKREMKTY-IPPKGE 220
Query: 351 TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWND 410
T K P PKRP SA F++ E +++ ERP LS ++ + L MWN+
Sbjct: 221 TKKKFKDP---------NAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNN 271
Query: 411 LSEKKKAKYKAREAALKAQSER 432
+ K Y+ R A LK + E+
Sbjct: 272 TAADDKQPYEKRSAKLKEKYEK 293
Score = 49.7 bits (117), Expect = 1e-05
Identities = 40/182 (21%), Positives = 83/182 (45%), Gaps = 31/182 (17%)
Query: 566 RWQRISQSQKEHYKKLA---EEQQKQYKVHLDLWVKSLSP---QDRAAYKEYISNKRKSM 619
RW+ +S +K + + E+ K K H +K+ P + + +K+ + KR
Sbjct: 177 RWKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETKKKFKDPNAPKRPPS 236
Query: 620 T----------KLRGPNPKSSRTTLQSK-----SESEEDDEEDEDDEDEDEEEEDDEN-- 662
K++G P S + K + + DD++ + +E+ +++
Sbjct: 237 AFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKRSAKLKEKYEKDIA 296
Query: 663 -------GDSSEDGG-DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSS 714
D++ +G +++S + E E+ +E+EED+E+E D+ED+DE++D + E
Sbjct: 297 AYRAKGKHDAANNGVVKAAKSKKKKEEEENEEDEEDEEEEKDEEDEDEEDDEDEEDGDDE 356
Query: 715 SS 716
S
Sbjct: 357 QS 358
Score = 45.8 bits (107), Expect = 1e-04
Identities = 42/165 (25%), Positives = 76/165 (46%), Gaps = 28/165 (16%)
Query: 392 RPELSESELTRLLARMWNDLSEKKKAKY-----------KAREAALKAQSER--KPGGER 438
R ++ SE ++ + W ++S K+K K+ KA +A K + + P GE
Sbjct: 162 RVSVNFSEFSKKCSERWKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGET 221
Query: 439 EERGKLPESPKRAEEIWQQSVIGDYLARFKNDRV-----KALKAMEMTWNNMEKKEKLMW 493
+++ K P +PKR + +Y + K +R K + WNN +K +
Sbjct: 222 KKKFKDPNAPKRPPSAFFL-YFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPY 280
Query: 494 IKKAAEDQKRYERELSEMRAP---PAATN------SSKKMKFQGE 529
K++A+ +++YE++++ RA AA N SKK K + E
Sbjct: 281 EKRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEE 325
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/136 (26%), Positives = 58/136 (42%), Gaps = 14/136 (10%)
Query: 58 VAFKDFSGDMCKLKWVEIS-NEVRKFRTLTELILDAQEHVKNPYKG------------KK 104
V F +FS C +W +S E KF D + K YK KK
Sbjct: 165 VNFSEFS-KKCSERWKNMSAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETKK 223
Query: 105 LKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQD 164
K P+ PK+P + +F +F E K P +S D+ K L + + K Y +
Sbjct: 224 KFKDPNAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKR 283
Query: 165 FQREKQEFERNLARFR 180
+ K+++E+++A +R
Sbjct: 284 SAKLKEKYEKDIAAYR 299
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 74.3 bits (181), Expect = 4e-13
Identities = 111/482 (23%), Positives = 202/482 (41%), Gaps = 111/482 (23%)
Query: 273 AELMANMKDVPSTERMVLCSQQWKLL--SQKEKDAYHKKCDQKKKDYEVELLRFLESLPE 330
A++ + K + S E + ++ +LL S++ + ++ D+++++ E E E E
Sbjct: 1037 AKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEE-----EEEDE 1091
Query: 331 EEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEE---KRRQ 387
EE++ EE+ NI Q++ P KP + + K KRP F+ ++ KRR+
Sbjct: 1092 EEEEEEEEEEEEENI---QSSPPRLTKP-----QSVAIKRKRP----FVLKKKRGRKRRR 1139
Query: 388 LQEERPELSESELTRLLARMWNDLSEKK-----------KAKYKAREAALKAQSERKPGG 436
+ + SE T +L +++ E++ + + R+ L+ + +PG
Sbjct: 1140 INSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGK 1199
Query: 437 ER---EERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEK-KEKLM 492
+R EE GK K A D ND LK E + +N E K K +
Sbjct: 1200 KRQTEEEEGKDNHCFKNA----------DPCRNNMNDDSSNLK--EGSKDNPEPLKCKQV 1247
Query: 493 WIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGE---PKKPPMNGYQKFS---QELL 546
W K +R LS+ R N +K F+ P + PM ++ + Q+
Sbjct: 1248 WPKGT-------KRGLSKWRQ-----NKERKTGFKLNLYTPPETPMEPDEQVTVEEQKET 1295
Query: 547 SNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRA 606
S G+ + P+ RI + KE + L +++
Sbjct: 1296 SEGKTSPSPI------------RIEEEVKETGEALLPQEE-------------------- 1323
Query: 607 AYKEYISNKRKSMTKLRGPNPKSSRTTLQS--KSESEEDDEEDEDDEDEDEEEEDDENGD 664
N+R+ PN K E EE++EE+E++E+E+EE E++E G
Sbjct: 1324 -------NRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGG 1376
Query: 665 SSEDGGDSSESSSEDESEDGDENEED---DEDEDDDEDDDEDEDNESEGSSSSSSSSGDS 721
+ E D ++S ++E E E E+ D+ E+++E+D+E NE + S +S
Sbjct: 1377 NVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMES 1436
Query: 722 SD 723
++
Sbjct: 1437 AE 1438
Score = 58.9 bits (141), Expect = 2e-08
Identities = 118/568 (20%), Positives = 204/568 (35%), Gaps = 112/568 (19%)
Query: 222 IMRDYIQKHPELNISEEGITKST--------LTKAERQLKDKFDGRPTKPPPNSYSLYCA 273
++ +Y+ H E +IS + I+++T T + DK DGR L
Sbjct: 909 VILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRREKLIL--- 965
Query: 274 ELMANMKDVPSTERMVLCSQQWK--LLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEE 331
M +K + S +W L+S ++++ + E E L S E+
Sbjct: 966 SHMEKLKTCSRANELDPDSLRWTPILISNAAVSE-----EEREAEKEAERLMEQASCWEK 1020
Query: 332 EQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEE 391
E+Q +L +A S S Q K RPV+ +R QL E
Sbjct: 1021 EEQEILST---------RANSRQSPAKVQSKNKYLHSPESRPVTG-------ERGQLLEL 1064
Query: 392 RPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRA 451
E SE E E+ + + + E + + E + E EE + SP R
Sbjct: 1065 SKESSEEEE-----------EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRL 1113
Query: 452 EEIWQQSVI----GDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERE 507
+ QSV ++ + K R + +T + + +++ D++R +
Sbjct: 1114 TK--PQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQ 1171
Query: 508 LS---EMRAPPAATNSSKKMKFQGEPKK-------------------PPMNGYQKFSQEL 545
L E+ + FQ +P K P N S L
Sbjct: 1172 LEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNL 1231
Query: 546 LSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDR 605
+ N PLK + V W + K K + ++++ L+L+ +P +
Sbjct: 1232 KEGSKDNPEPLKCKQV-----WPK---GTKRGLSKWRQNKERKTGFKLNLYTPPETPMEP 1283
Query: 606 AAYKEYISNKRKSMTKLRGPNP-------KSSRTTLQSKSESEEDD------------EE 646
K S K P+P K + L + E+ ++ E+
Sbjct: 1284 DEQVTVEEQKETSEGKT-SPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEK 1342
Query: 647 DEDD----EDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE---- 698
EDD E+E+EEEE++E + E+G + + ++ DG +++E +E E E
Sbjct: 1343 PEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDS 1402
Query: 699 ---DDDEDEDNESEGSSSSSSSSGDSSD 723
DD E+E+ E E S + D D
Sbjct: 1403 ARLDDHEEEEEEDEEPSHNEDHDADDED 1430
Score = 37.7 bits (86), Expect = 0.038
Identities = 30/139 (21%), Positives = 62/139 (44%), Gaps = 29/139 (20%)
Query: 615 KRKSMTKLRGPNPKSSRTT---LQSKSESEEDDEEDEDDED--------EDEEEEDDENG 663
K K+ ++ +P S R T + + + SEE+ E +++ E E EE+E
Sbjct: 970 KLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTR 1029
Query: 664 DSSEDGGDSSESSSE------------------DESEDGDENEEDDEDEDDDEDDDEDED 705
+S +S ++ + S++ E EE++EDE+++E+++E+E+
Sbjct: 1030 ANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEE 1089
Query: 706 NESEGSSSSSSSSGDSSDS 724
+E E ++ S
Sbjct: 1090 DEEEEEEEEEEEEEENIQS 1108
Score = 30.0 bits (66), Expect = 7.9
Identities = 54/278 (19%), Positives = 105/278 (37%), Gaps = 22/278 (7%)
Query: 442 GKLPESPKRAEEIWQQSVIGD-YLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED 500
GK SP R EE +++ G+ L + +N R + + + EK E + IK E+
Sbjct: 1298 GKTSPSPIRIEEEVKET--GEALLPQEENRREETCAPVSPNTSPGEKPEDDL-IKPEEEE 1354
Query: 501 QKRYERELSE-------------MRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLS 547
++ E E E + P S +K + + +K +E
Sbjct: 1355 EEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEE 1414
Query: 548 NGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAA 607
+ E +H + E S + ++E ++ +E + + LDL V Q +
Sbjct: 1415 DEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNV-----QPGHS 1469
Query: 608 YKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE 667
E + + +T PK ++ ES+E+ E + +D++ + + + E
Sbjct: 1470 NPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKE 1529
Query: 668 DGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDED 705
+ E SE +E E +D +D E ++
Sbjct: 1530 GNPATMEIDSETVQAVQSLTQESSEQDDTFQDCAETQE 1567
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 74.3 bits (181), Expect = 4e-13
Identities = 80/379 (21%), Positives = 153/379 (40%), Gaps = 35/379 (9%)
Query: 366 GSEKPKRPVSAMF-IFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREA 424
G EK V + I E+KRR+ QEE+ +E+ RL D + + R+
Sbjct: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEK-----AEIKRLKNSDDRDSKRDSLEEGELRDH 56
Query: 425 ALKAQSERKP---GGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMT 481
++ P E+RG+ E A + QQ + + K+++ K K +
Sbjct: 57 CMEITIRNSPYRREDSMEDRGE--EDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVK 114
Query: 482 WNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKF 541
E + + K+ E+Q + RE + A S++ + + E + +K
Sbjct: 115 EKEREHERR----KRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKM 170
Query: 542 SQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLS 601
++ E +ER E + + + H++ + E+ KV W +S
Sbjct: 171 REQQKEQREQKE---RERRAEERRKEREARREVSAHHRTMREDYSD--KVKASHWSRSPP 225
Query: 602 PQDRAAY---------KEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDED 652
R + KE +R ++ L+ + +T+ S +E +E++E+
Sbjct: 226 RPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEE 285
Query: 653 EDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEG-- 710
E+EEEE+ + SE+ + E E+ + +E E +E +E+ EDE+ E+E
Sbjct: 286 EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHL 345
Query: 711 ----SSSSSSSSGDSSDSD 725
S SG+S +++
Sbjct: 346 LVVPESRFDRDSGESEEAE 364
Score = 71.6 bits (174), Expect = 2e-12
Identities = 76/337 (22%), Positives = 146/337 (43%), Gaps = 45/337 (13%)
Query: 411 LSEKKKAKYKAREAA---LKAQSERKPGGEREERGKLPE---------SPKRAEEIWQQS 458
L EKK+ K + +A LK +R + E G+L + SP R E+ +
Sbjct: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMED- 75
Query: 459 VIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRY------ERELSEMR 512
R + D A+K + M +KEK+ K +K++ ERE E R
Sbjct: 76 -------RGEEDDSLAIKPPQQ----MSRKEKVHHRKDEKRKEKKHARVKEKERE-HERR 123
Query: 513 APPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQ 572
+ +++ + ++ + + ++ L E ++R E R Q+ Q
Sbjct: 124 KRHREEQDKARREWERQKRREMAREHSRRERDRLEQLE------RKRERERKMREQQKEQ 177
Query: 573 SQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRT 632
+++ ++ AEE++K+ + + +S R ++Y + S P P R
Sbjct: 178 REQKERERRAEERRKEREAR-----REVSAHHRTMREDYSDKVKASHWSRSPPRPPRERF 232
Query: 633 TLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDE 692
L + ++++ +E D D ++ D +S S+ES S E E+ +E EE++E
Sbjct: 233 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 292
Query: 693 ---DEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726
E+ +E+++E+E+ E E S+S +S S++ S
Sbjct: 293 GSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 329
Score = 60.8 bits (146), Expect = 4e-09
Identities = 92/426 (21%), Positives = 164/426 (38%), Gaps = 81/426 (19%)
Query: 322 LRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFS 381
++ L+ + +E+++R EEK K + SK+ + E G E + S
Sbjct: 10 VKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEG----ELRDHCMEITIRNS 65
Query: 382 EEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREE- 440
+R E+R E +S L + +S K+K ++ E + + R ERE
Sbjct: 66 PYRREDSMEDRGEEDDS----LAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHE 121
Query: 441 -RGKLPESPKRAEEIWQQSVIGDYL---ARFKNDRVKALKAMEMTWNNMEKKEKLMWIKK 496
R + E +A W++ + +R + DR++ L+ E++ K+ +K
Sbjct: 122 RRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLE------RKRERERKMREQQK 175
Query: 497 AAEDQKRYERELSEMRAPPAATNS------------SKKMKFQGEPKKPPMNGYQKFSQE 544
+QK ER E R A S K+K + PP
Sbjct: 176 EQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPR--------- 226
Query: 545 LLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQD 604
P +ER E+G + K + EE+ ++ + DL + +S +
Sbjct: 227 ----------PPRERF-ELG-----------DGRKPVKEEKMEERDLLSDL--QDISDSE 262
Query: 605 RAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGD 664
R S+ + S SE E++EE+ EEEE++E G
Sbjct: 263 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE-------EEEEEEETGS 315
Query: 665 SSEDGGD-SSESSSEDESEDGDENEEDDE---------DEDDDEDDDEDEDNESEGSSSS 714
+SE+ + S+E SE+E + +E E ++ D D E ++ +E+ SS
Sbjct: 316 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 375
Query: 715 SSSSGD 720
+ + GD
Sbjct: 376 ALTEGD 381
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 73.9 bits (180), Expect = 5e-13
Identities = 95/515 (18%), Positives = 203/515 (39%), Gaps = 51/515 (9%)
Query: 233 LNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKD----VPSTERM 288
L + IT L K +L++K R + + L EL ++ +P +
Sbjct: 173 LELYRNTITNEELKKKNAELQEKL--RLAESEKSEIQLNVKELKRKLERAKFLLPQVQTN 230
Query: 289 VLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKK 348
L + W+ + + + ++K + E LR E E+++++ +EK L +K
Sbjct: 231 TLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEK 290
Query: 349 QATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMW 408
+ + Q+ + E+ + +E++ QEE+ E ++ R R+W
Sbjct: 291 ELREQEKELREQKKLREQEEQMQE---------QEEKMWEQEEKMREQEEKMWRQEERLW 341
Query: 409 NDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSV--------I 460
+ ++ + K R+ + + + E+EER + E EE Q+ +
Sbjct: 342 EQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKM 401
Query: 461 GDYLARFKNDRVKALKAMEMTWNNMEK----------KEKLMWIKKAAEDQKRYERELSE 510
+ + K K E W EK KEKL +K E +++ + +
Sbjct: 402 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461
Query: 511 MRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRI 570
+R KKM Q + ++ +++ +E + + E +ERM E R +
Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQ--EEKMRDQEQKMWDQEERMWEQDERLREK 519
Query: 571 SQSQKEHYKKLA-EEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTK----LRGP 625
+ +E K EE+ ++ K + K+ +++ +E + + K M + +R
Sbjct: 520 EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 579
Query: 626 NPKSSRTTLQSKSESEEDDEEDEDDEDEDE-----------EEEDDENGDSSEDGGDSSE 674
K + + + E+ E++E ++++E +EE+D+ + E + E
Sbjct: 580 EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEE 639
Query: 675 SSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709
E E + ++ E+ E E+ + +E + E
Sbjct: 640 KMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 674
Score = 71.6 bits (174), Expect = 2e-12
Identities = 111/582 (19%), Positives = 233/582 (40%), Gaps = 62/582 (10%)
Query: 126 KRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPD 185
+RAK+ L P++ L + + ++ +EL E++K ++++++ R R RE
Sbjct: 218 ERAKF--LLPQVQTNTLQEEMWRQEEELREQEKK-----IRKQEEKMWRQEERLREQEGK 270
Query: 186 LIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGITKSTL 245
+ + +K EK Q+ ++K + + + +Q+ E +E +
Sbjct: 271 MREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE 330
Query: 246 TKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDA 305
K RQ + ++ E M+D ERM Q +L ++E+
Sbjct: 331 EKMWRQEERLWEQEKQM----------REQEQKMRD--QEERM--WEQDERLREKEERMR 376
Query: 306 YHKKC-DQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGK 364
+K +Q++K E E +R E EE++ + +E+ + ++ K+ Q+
Sbjct: 377 EQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436
Query: 365 GGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREA 424
EK ++ +EK ++ +E+ E + E R MW EKK R+
Sbjct: 437 EQKEK---------LWEQEKMQEQEEKIWE--QEEKIRDQEEMWGQ--EKKMW----RQE 479
Query: 425 ALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNN 484
++ Q ++ E + R + + + E +W+Q D R K +R++ K M
Sbjct: 480 KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQ----DERLREKEERMREQKKMWQQEEK 535
Query: 485 MEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQE 544
M +++K +K DQ+ RE MR ++M + E K + +E
Sbjct: 536 MREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE 595
Query: 545 LLSNGELNHLPLKERMVEIGSR-WQRISQSQKEHYKKLA-EEQQKQYKVHLDLWVKSLSP 602
+ E +E+M E + W++ + + + +++ E+++K + +W
Sbjct: 596 KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW------ 649
Query: 603 QDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDEN 662
+ +E R+ K++G K E +E+ + E++ E+E+
Sbjct: 650 EQEEKMREQEEKMREQEEKMQGQEEKM-----------REQEEKMQGQEEKMREQEEKMR 698
Query: 663 GDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDE 704
G + G + ++E G E + E+ D+ + E
Sbjct: 699 GQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQE 740
Score = 65.9 bits (159), Expect = 1e-10
Identities = 110/581 (18%), Positives = 232/581 (39%), Gaps = 68/581 (11%)
Query: 156 KKKMKYIQDFQREKQ----EFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEK 211
KK +YI++ +E+ E RN E + +K + E K+ QL K
Sbjct: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
Query: 212 K-------VYLKVRPDEIMRDYIQKHPELNISEEGITKST--LTKAERQLKD---KFDGR 259
+ + +V+ + + + ++ EL E+ I K + + E +L++ K +
Sbjct: 215 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 274
Query: 260 PTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEV 319
K L E ++ E+ L Q+ ++ Q+EK + ++K ++ E
Sbjct: 275 EEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEK---MWEQEEKMREQEE 331
Query: 320 ELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGS---EKPKRPVSA 376
++ R E L E+E+Q E+KM + ++ + +E + E+ ++
Sbjct: 332 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEE 391
Query: 377 MFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGG 436
I EK+ + +EE E ++ + MW EK+ + + E K + K
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQ-EEKEWQQQRLPEQKEKLWEQEKMQE 450
Query: 437 EREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEK---KEKLMW 493
+ E+ + E + EE+W G ++ ++++ + + W EK +E+ MW
Sbjct: 451 QEEKIWEQEEKIRDQEEMW-----GQEKKMWRQEKMREQE--DQMWEQEEKMRDQEQKMW 503
Query: 494 IKKAA--EDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGEL 551
++ E +R + MR +KM+ E KK + + QE E
Sbjct: 504 DQEERMWEQDERLREKEERMREQKKMWQQEEKMR---EEKKTQEQEKKTWDQEEKMREE- 559
Query: 552 NHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEY 611
ERM E + + + +E +K+ E+++K + +W + Q++ +E
Sbjct: 560 ------ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ---EEK 610
Query: 612 ISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDD---EDEDEEEEDDENGDSSED 668
+ + + M + + EED +++++ E E++ +E +E E+
Sbjct: 611 MWEQEEKMWE-----------------QEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEE 653
Query: 669 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709
E ++ E EE ++++ E++ E E
Sbjct: 654 KMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQE 694
Score = 60.1 bits (144), Expect = 7e-09
Identities = 85/401 (21%), Positives = 154/401 (38%), Gaps = 41/401 (10%)
Query: 146 LSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQL 205
L +K + + E++KM ++ +E++ + RE+ + + +K K + +
Sbjct: 368 LREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQ-----KQEENM 422
Query: 206 WYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGI-----------------TKSTLTKA 248
W EK+ + P++ ++ + + ++ EE I K +
Sbjct: 423 WEQEEKEWQQQRLPEQ--KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 480
Query: 249 ERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHK 308
R+ +D+ + K ++ E +D E+ +Q K+ Q+EK K
Sbjct: 481 MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEK 540
Query: 309 KC--------DQKKKDYEVELLRFLES-LPEEEQQRVLGEEKMLNINKKQATSPASKKPA 359
K DQ++K E E +R E + EEE+ EEKM +K
Sbjct: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600
Query: 360 QEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKY 419
+E + EK M+ EE + Q QEE E ++ +MW + ++ +
Sbjct: 601 EEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 660
Query: 420 KAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAME 479
K RE K Q + + E+EE+ + E R +E + + G + K E
Sbjct: 661 KMREQEEKMQGQEEKMREQEEKMQGQEEKMREQE---EKMRGQE-EKMWGQEEKMWGQEE 716
Query: 480 MTWNNMEKKEKLMWIK----KAAEDQKRYERELSEMRAPPA 516
W E +EK I+ K E +E SE PP+
Sbjct: 717 KMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPS 757
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 73.9 bits (180), Expect = 5e-13
Identities = 33/84 (39%), Positives = 56/84 (66%), Gaps = 1/84 (1%)
Query: 638 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDD 697
S+ ED EDE+++DE+E+EEDDE+ D S+D S+S+SE ++E +E ++DD+D+D+
Sbjct: 601 SKDSEDSNEDEEEDDEEEDEEDDED-DESDDSQSESDSNSESDTEGSEEEDDDDKDQDES 659
Query: 698 EDDDEDEDNESEGSSSSSSSSGDS 721
+ D E E + + ++SS S
Sbjct: 660 DSDTEGEKTSMKLNKTTSSVKSPS 683
Score = 70.1 bits (170), Expect = 7e-12
Identities = 31/79 (39%), Positives = 48/79 (60%)
Query: 640 SEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDED 699
S +D E+ +DE+ED+EEED+E+ + E SES S ES+ EEDD+D+D DE
Sbjct: 600 SSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDES 659
Query: 700 DDEDEDNESEGSSSSSSSS 718
D + E ++ + ++SS
Sbjct: 660 DSDTEGEKTSMKLNKTTSS 678
Score = 65.1 bits (157), Expect = 2e-10
Identities = 33/115 (28%), Positives = 58/115 (50%), Gaps = 1/115 (0%)
Query: 612 ISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 671
+SN + +P S ++S+ +D +D +EDEEE DDE D +D D
Sbjct: 568 VSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEE-DDEEEDEEDDEDD 626
Query: 672 SSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726
S+ S + + + + E E+EDDD+ D ++ D+++EG +S + +S S
Sbjct: 627 ESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKS 681
Score = 58.9 bits (141), Expect = 2e-08
Identities = 24/68 (35%), Positives = 41/68 (60%)
Query: 660 DENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719
D + SS+D DS+E ED+ E+ +E++EDDE +D + D + ++++EGS
Sbjct: 595 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDK 654
Query: 720 DSSDSDSN 727
D +SDS+
Sbjct: 655 DQDESDSD 662
Score = 55.8 bits (133), Expect = 1e-07
Identities = 25/60 (41%), Positives = 42/60 (70%), Gaps = 2/60 (3%)
Query: 670 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDE--DNESEGSSSSSSSSGDSSDSDSN 727
G S+ S +SED +E+EE+D++E+D+EDD++DE D++SE S+S S + S + D +
Sbjct: 593 GTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDD 652
Score = 53.1 bits (126), Expect = 9e-07
Identities = 21/79 (26%), Positives = 38/79 (48%)
Query: 649 DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 708
D + ++ +D N D ED + E ED+ D ++E D E D E +E++D++
Sbjct: 595 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDK 654
Query: 709 EGSSSSSSSSGDSSDSDSN 727
+ S S + G+ + N
Sbjct: 655 DQDESDSDTEGEKTSMKLN 673
Score = 52.8 bits (125), Expect = 1e-06
Identities = 29/91 (31%), Positives = 55/91 (60%), Gaps = 2/91 (2%)
Query: 630 SRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE-DGGDSSESSSED-ESEDGDEN 687
+R Q +S+++ D + +D+ ++ E+ +S+ D G SS++SSE S D D+
Sbjct: 209 NRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDL 268
Query: 688 EEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 718
EED+E+ED ++ ED+D++SE + S++
Sbjct: 269 EEDEEEEDQSIEESEDDDSDSESEAQHKSNN 299
Score = 42.7 bits (99), Expect = 0.001
Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 11/108 (10%)
Query: 610 EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDG 669
+Y+SN R+ + G K + +K + D D +E G
Sbjct: 1236 DYMSNLRRDKWVVEGKLRKLR--IIHAKKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRK 1293
Query: 670 GDSSESSSEDESEDGDENEEDDEDEDDDED---------DDEDEDNES 708
G S+ +D+ + D+ +EDDEDE+D ED +DEDE +++
Sbjct: 1294 GGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQA 1341
Score = 42.4 bits (98), Expect = 0.002
Identities = 22/65 (33%), Positives = 37/65 (56%), Gaps = 7/65 (10%)
Query: 625 PNPKSSRTTLQSKSESEEDDEEDEDD----EDEDEEEEDDENG---DSSEDGGDSSESSS 677
P P R S+ ++DD++D DD +DEDEE+++D+ G D ED + +++S
Sbjct: 1284 PTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAAS 1343
Query: 678 EDESE 682
+E E
Sbjct: 1344 VEELE 1348
Score = 41.2 bits (95), Expect = 0.003
Identities = 17/63 (26%), Positives = 32/63 (50%)
Query: 627 PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDE 686
P R + +S+ DD++D+D +D+ +E+++DE + G + EDE +
Sbjct: 1284 PTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAAS 1343
Query: 687 NEE 689
EE
Sbjct: 1344 VEE 1346
Score = 40.0 bits (92), Expect = 0.008
Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 612 ISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 671
I +K+ + + S + S + SE D DD +EDEEEE D++ + SED
Sbjct: 229 IKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEE-DQSIEESEDDDS 287
Query: 672 SSESSSEDESED 683
SES ++ +S +
Sbjct: 288 DSESEAQHKSNN 299
Score = 38.9 bits (89), Expect = 0.017
Identities = 47/195 (24%), Positives = 83/195 (42%), Gaps = 19/195 (9%)
Query: 323 RFLESLPEEEQQRVLGEEKMLN-INKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFS 381
+ L L +E R + K+L + K++ A + Q+ EK K+ +
Sbjct: 884 KLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQ 943
Query: 382 EEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREA-ALKAQSERKPGGEREE 440
+EK +++Q+ R E EL R L KKK K +A A L+A+ K R +
Sbjct: 944 QEKIKRIQQIR---MEKEL-----RAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQ 995
Query: 441 RGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED 500
+ L + +R ++ AR K + + LK + + K+ KL +
Sbjct: 996 QAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKL--------E 1047
Query: 501 QKRYERELS-EMRAP 514
Q+R E E++ E++ P
Sbjct: 1048 QRRLELEMAKELKKP 1062
Score = 38.5 bits (88), Expect = 0.022
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 621 KLRGPNPKSSRTTLQSKSESEEDDEEDEDDE-----DEDEEEEDDENGDSSEDGGDSSES 675
K++ P+ S S+S+ D E D D+ EED+E D S + + +S
Sbjct: 228 KIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDS 287
Query: 676 SSEDESEDGDENE 688
SE E++ N+
Sbjct: 288 DSESEAQHKSNNQ 300
Score = 37.4 bits (85), Expect = 0.050
Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 626 NPKSSRTTLQSKSESEEDDEEDEDDED--EDEEEEDDENGDSSEDGGDSSESSSEDESED 683
+P + T + + D + D+DD+D +D+ +EDDE+ + ED EDE E
Sbjct: 1279 HPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDE- 1337
Query: 684 GDENEEDDEDEDDDE 698
GD+ +E E E
Sbjct: 1338 GDQAASVEELEKQIE 1352
Score = 37.0 bits (84), Expect = 0.065
Identities = 17/70 (24%), Positives = 33/70 (47%), Gaps = 4/70 (5%)
Query: 644 DEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE----EDDEDEDDDED 699
D++ E D ++G SS+ + SS D+ E+ +E E E+ ED+D D +
Sbjct: 231 DKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSE 290
Query: 700 DDEDEDNESE 709
+ + ++
Sbjct: 291 SEAQHKSNNQ 300
Score = 36.6 bits (83), Expect = 0.085
Identities = 13/42 (30%), Positives = 23/42 (54%)
Query: 684 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 725
GD + +DD+D+D D+ DED+++E + + D D
Sbjct: 1295 GDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDED 1336
Score = 36.6 bits (83), Expect = 0.085
Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 2/64 (3%)
Query: 655 EEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE--DDEDEDDDEDDDEDEDNESEGSS 712
+ + DD++ D S+D GD + ED+ + + + +DEDE D E+ + + E S
Sbjct: 1296 DSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLS 1355
Query: 713 SSSS 716
S
Sbjct: 1356 KQQS 1359
Score = 36.2 bits (82), Expect = 0.11
Identities = 15/78 (19%), Positives = 36/78 (46%)
Query: 632 TTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDD 691
T + + + D DD+D+D+ ++ + D E+ + + D ED DE ++
Sbjct: 1283 TPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAA 1342
Query: 692 EDEDDDEDDDEDEDNESE 709
E+ ++ ++ +S+
Sbjct: 1343 SVEELEKQIEKLSKQQSQ 1360
Score = 35.8 bits (81), Expect = 0.14
Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 683 DGDENEEDDEDEDDDED-DDEDEDNESEGSSSSSSSSGDSSDSD 725
D D +++DD+D DD D DDEDE+++ + + D + D
Sbjct: 1296 DSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGD 1339
Score = 34.7 bits (78), Expect = 0.32
Identities = 31/132 (23%), Positives = 57/132 (43%), Gaps = 6/132 (4%)
Query: 565 SRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRG 624
S Q S S +K +EQ K LD V + +D+ K+ + + S +
Sbjct: 196 SMGQTKSTSSGGGNRKCNQEQSKNQP--LDARVDKI--KDKKPRKKAMESSSNSDSDSGT 251
Query: 625 PNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSE--SSSEDESE 682
+ SS S S+ E+DEE+ED E+ E++D ++ ++ ++ D
Sbjct: 252 SSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKA 311
Query: 683 DGDENEEDDEDE 694
DG + E +++
Sbjct: 312 DGQKATEKAQEK 323
Score = 33.1 bits (74), Expect = 0.94
Identities = 15/56 (26%), Positives = 27/56 (48%)
Query: 672 SSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
S + S E G +++ + +D ++DE+ED+E E D S S+S+
Sbjct: 581 SHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESD 636
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 72.4 bits (176), Expect = 1e-12
Identities = 35/96 (36%), Positives = 61/96 (63%), Gaps = 8/96 (8%)
Query: 624 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESED 683
GPN + T+L+S+ E EE++EE+E++E+ + EEE++E + E+GG+ E E+E
Sbjct: 392 GPNATIT-TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEE--- 447
Query: 684 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719
E++ D D DE+++EDE++ SEG + + G
Sbjct: 448 ----VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQG 479
Score = 57.8 bits (138), Expect = 4e-08
Identities = 39/99 (39%), Positives = 49/99 (49%), Gaps = 39/99 (39%)
Query: 641 EEDDEEDEDDEDEDEEEEDDENGDS----SED---------------------------- 668
EE++ E+E D D DEEEE+DE S +ED
Sbjct: 444 EEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHF 503
Query: 669 --GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDED 705
GG+ S+S SE+E D+ EEDDEDEDDD DD+ED D
Sbjct: 504 LEGGEDSDSDSEEE----DDEEEDDEDEDDD-DDEEDGD 537
Score = 42.7 bits (99), Expect = 0.001
Identities = 18/29 (62%), Positives = 27/29 (93%), Gaps = 1/29 (3%)
Query: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGD 664
S S+SEE+D+E+EDDEDED +++D+E+GD
Sbjct: 510 SDSDSEEEDDEEEDDEDED-DDDDEEDGD 537
Score = 40.0 bits (92), Expect = 0.008
Identities = 15/48 (31%), Positives = 29/48 (60%)
Query: 624 GPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 671
G ++ TL E+ D + E+++DE+E++ED+++ D EDG +
Sbjct: 491 GAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
Score = 37.7 bits (86), Expect = 0.038
Identities = 14/51 (27%), Positives = 29/51 (56%)
Query: 677 SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
SE E E+ +E EE++E+ + +E+++E E+ E EG + + + +
Sbjct: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD 453
Score = 36.6 bits (83), Expect = 0.085
Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Query: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDE---DNESEGSSSSSSSSGDSSDSD 725
SE E+E E+ +E EE + +E+++E ++E+E + E G GD DSD
Sbjct: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD-VDSD 457
Score = 32.0 bits (71), Expect = 2.1
Identities = 14/42 (33%), Positives = 26/42 (61%), Gaps = 2/42 (4%)
Query: 669 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEG 710
GG + + + +G+E EE E+E+++E++ E E+ E EG
Sbjct: 390 GGGPNATITTSLKSEGEEEEE--EEEEEEEEEGEGEEEEEEG 429
Score = 30.0 bits (66), Expect = 7.9
Identities = 11/35 (31%), Positives = 21/35 (60%)
Query: 622 LRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEE 656
L G S + + E +++DE+D+DDE++ +E
Sbjct: 504 LEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 71.6 bits (174), Expect = 2e-12
Identities = 73/333 (21%), Positives = 142/333 (42%), Gaps = 28/333 (8%)
Query: 411 LSEKKKAKYKAREAA---LKAQSERKPGGEREERGKLPE---------SPKRAEEIWQQS 458
L EKK+ K + +A LK +R + E G+L + SP R E+ +
Sbjct: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76
Query: 459 VIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQK--RYERELSEMRAPPA 516
D K + + K + ++KEK +AE K R + E R
Sbjct: 77 GEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKEREHERRKRHR 136
Query: 517 ATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKE 576
+ +++ + ++ + + ++ L E ++R E R Q+ Q +++
Sbjct: 137 EEQDKARREWERQKRREMAREHSRRERDRLEQLE------RKRERERKMREQQKEQREQK 190
Query: 577 HYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQS 636
++ AEE++K+ + + +S R ++Y + S P P R L
Sbjct: 191 ERERRAEERRKEREAR-----REVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGD 245
Query: 637 KSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDE---D 693
+ ++++ +E D D ++ D +S S+ES S E E+ +E EE++E
Sbjct: 246 GRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS 305
Query: 694 EDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726
E+ +E+++E+E+ E E S+S +S S++ S
Sbjct: 306 EESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 338
Score = 68.9 bits (167), Expect = 2e-11
Identities = 76/383 (19%), Positives = 153/383 (39%), Gaps = 34/383 (8%)
Query: 366 GSEKPKRPVSAMF-IFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKY----K 420
G EK V + I E+KRR+ QEE+ E+ + + + L E + +
Sbjct: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEIT 61
Query: 421 AREAALKAQSERKPGGEREERG--KLPESPKRAEEIW-QQSVIGDYLARFKNDRVKALKA 477
R + + + + GE ++ K P+ R E++ ++ R + + K
Sbjct: 62 IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKH 121
Query: 478 MEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNG 537
+ E++ K+ E+Q + RE + A S++ + + E +
Sbjct: 122 ARVKEREHERR------KRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRER 175
Query: 538 YQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWV 597
+K ++ E +ER E + + + H++ + E+ KV W
Sbjct: 176 ERKMREQQKEQREQKE---RERRAEERRKEREARREVSAHHRTMREDYSD--KVKASHWS 230
Query: 598 KSLSPQDRAAY---------KEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDE 648
+S R + KE +R ++ L+ + +T+ S +E +E
Sbjct: 231 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE 290
Query: 649 DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 708
++E+E+EEEE+ + SE+ + E E+ + +E E +E +E+ EDE+ E+
Sbjct: 291 EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEEREN 350
Query: 709 EG------SSSSSSSSGDSSDSD 725
E S SG+S +++
Sbjct: 351 ENHLLVVPESRFDRDSGESEEAE 373
Score = 58.9 bits (141), Expect = 2e-08
Identities = 93/435 (21%), Positives = 165/435 (37%), Gaps = 90/435 (20%)
Query: 322 LRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFS 381
++ L+ + +E+++R EEK K + SK+ + E G E + S
Sbjct: 10 VKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEG----ELRDHCMEITIRNS 65
Query: 382 EEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKA---REAALKAQSERKPGG-- 436
+R E+R E +S L + +S K+K ++ R+ + S GG
Sbjct: 66 PYRREDSMEDRGEEDDS----LAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKH 121
Query: 437 ------EREERGKLPESPKRAEEIWQQSVIGDYL---ARFKNDRVKALKAMEMTWNNMEK 487
E E R + E +A W++ + +R + DR++ L+ E+
Sbjct: 122 ARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLE------RKRER 175
Query: 488 KEKLMWIKKAAEDQKRYERELSEMRAPPAATNS------------SKKMKFQGEPKKPPM 535
+ K+ +K +QK ER E R A S K+K + PP
Sbjct: 176 ERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPR 235
Query: 536 NGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDL 595
P +ER E+G + K + EE+ ++ + DL
Sbjct: 236 -------------------PPRERF-ELG-----------DGRKPVKEEKMEERDLLSDL 264
Query: 596 WVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDE 655
+ +S +R S+ + S SE E++EE+ E
Sbjct: 265 --QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE-------E 315
Query: 656 EEEDDENGDSSEDGGD-SSESSSEDESEDGDENEEDDE---------DEDDDEDDDEDED 705
EEE++E G +SE+ + S+E SE+E + +E E ++ D D E ++ +E+
Sbjct: 316 EEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 375
Query: 706 NESEGSSSSSSSSGD 720
SS+ + GD
Sbjct: 376 VGEGTPQSSALTEGD 390
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.125 0.352
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,836,641
Number of Sequences: 37866
Number of extensions: 1702071
Number of successful extensions: 66776
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1241
Number of HSP's successfully gapped in prelim test: 754
Number of HSP's that attempted gapping in prelim test: 15516
Number of HSP's gapped (non-prelim): 21230
length of query: 727
length of database: 18,247,518
effective HSP length: 110
effective length of query: 617
effective length of database: 14,082,258
effective search space: 8688753186
effective search space used: 8688753186
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.