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Search of human proteins with 23510356
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23510356 RIO kinase 1 isoform 1 [Homo sapiens]
(568 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23510356 RIO kinase 1 isoform 1 [Homo sapiens] 1140 0.0
gi|23510358 RIO kinase 1 isoform 2 [Homo sapiens] 655 0.0
gi|22325377 sudD suppressor of bimD6 homolog [Homo sapiens] 274 1e-73
gi|229331967 RIO kinase 2 isoform 1 [Homo sapiens] 61 2e-09
gi|229331971 RIO kinase 2 isoform 2 [Homo sapiens] 61 2e-09
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 41 0.003
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 40 0.004
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 40 0.004
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 40 0.004
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 40 0.004
gi|31543392 peroxisome proliferator-activated receptor gamma, co... 40 0.006
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 40 0.007
gi|156071452 nardilysin isoform b [Homo sapiens] 40 0.007
gi|156071450 nardilysin isoform a [Homo sapiens] 40 0.007
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 40 0.007
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear... 39 0.010
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear... 39 0.010
gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens] 39 0.010
gi|170763500 SET translocation (myeloid leukemia-associated) iso... 39 0.010
gi|170763498 SET translocation (myeloid leukemia-associated) iso... 39 0.010
gi|62243374 MAD1-like 1 protein [Homo sapiens] 39 0.010
gi|62243369 MAD1-like 1 protein [Homo sapiens] 39 0.010
gi|62243332 MAD1-like 1 protein [Homo sapiens] 39 0.010
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 39 0.013
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 39 0.013
gi|115529449 upstream binding transcription factor, RNA polymera... 39 0.013
gi|115529451 upstream binding transcription factor, RNA polymera... 39 0.013
gi|7657671 upstream binding transcription factor, RNA polymerase... 39 0.013
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 39 0.017
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 39 0.017
>gi|23510356 RIO kinase 1 isoform 1 [Homo sapiens]
Length = 568
Score = 1140 bits (2949), Expect = 0.0
Identities = 568/568 (100%), Positives = 568/568 (100%)
Query: 1 MDYRRLLMSRVVPGQFDDADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEE 60
MDYRRLLMSRVVPGQFDDADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEE
Sbjct: 1 MDYRRLLMSRVVPGQFDDADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEE 60
Query: 61 EGYDDDDDDWDWDEGVGKLAKGYVWNGGSNPQANRQTSDSSSAKMSTPADKVLRKFENKI 120
EGYDDDDDDWDWDEGVGKLAKGYVWNGGSNPQANRQTSDSSSAKMSTPADKVLRKFENKI
Sbjct: 61 EGYDDDDDDWDWDEGVGKLAKGYVWNGGSNPQANRQTSDSSSAKMSTPADKVLRKFENKI 120
Query: 121 NLDKLNVTDSVINKVTEKSRQKEADMYRIKDKADRATVEQVLDPRTRMILFKMLTRGIIT 180
NLDKLNVTDSVINKVTEKSRQKEADMYRIKDKADRATVEQVLDPRTRMILFKMLTRGIIT
Sbjct: 121 NLDKLNVTDSVINKVTEKSRQKEADMYRIKDKADRATVEQVLDPRTRMILFKMLTRGIIT 180
Query: 181 EINGCISTGKEANVYHASTANGESRAIKIYKTSILVFKDRDKYVSGEFRFRHGYCKGNPR 240
EINGCISTGKEANVYHASTANGESRAIKIYKTSILVFKDRDKYVSGEFRFRHGYCKGNPR
Sbjct: 181 EINGCISTGKEANVYHASTANGESRAIKIYKTSILVFKDRDKYVSGEFRFRHGYCKGNPR 240
Query: 241 KMVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLKNVQLSESKA 300
KMVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLKNVQLSESKA
Sbjct: 241 KMVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLKNVQLSESKA 300
Query: 301 RELYLQVIQYMRRMYQDARLVHADLSEFNMLYHGGGVYIIDVSQSVEHDHPHALEFLRKD 360
RELYLQVIQYMRRMYQDARLVHADLSEFNMLYHGGGVYIIDVSQSVEHDHPHALEFLRKD
Sbjct: 301 RELYLQVIQYMRRMYQDARLVHADLSEFNMLYHGGGVYIIDVSQSVEHDHPHALEFLRKD 360
Query: 361 CANVNDFFMRHSVAVMTVRELFEFVTDPSITHENMDAYLSKAMEIASQRTKEERSSQDHV 420
CANVNDFFMRHSVAVMTVRELFEFVTDPSITHENMDAYLSKAMEIASQRTKEERSSQDHV
Sbjct: 361 CANVNDFFMRHSVAVMTVRELFEFVTDPSITHENMDAYLSKAMEIASQRTKEERSSQDHV 420
Query: 421 DEEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQ 480
DEEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQ
Sbjct: 421 DEEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQ 480
Query: 481 KVPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKE 540
KVPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKE
Sbjct: 481 KVPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKE 540
Query: 541 AQREKRKNKIPKHVKKRKEKTAKTKKGK 568
AQREKRKNKIPKHVKKRKEKTAKTKKGK
Sbjct: 541 AQREKRKNKIPKHVKKRKEKTAKTKKGK 568
>gi|23510358 RIO kinase 1 isoform 2 [Homo sapiens]
Length = 327
Score = 655 bits (1689), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 242 MVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLKNVQLSESKAR 301
MVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLKNVQLSESKAR
Sbjct: 1 MVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLKNVQLSESKAR 60
Query: 302 ELYLQVIQYMRRMYQDARLVHADLSEFNMLYHGGGVYIIDVSQSVEHDHPHALEFLRKDC 361
ELYLQVIQYMRRMYQDARLVHADLSEFNMLYHGGGVYIIDVSQSVEHDHPHALEFLRKDC
Sbjct: 61 ELYLQVIQYMRRMYQDARLVHADLSEFNMLYHGGGVYIIDVSQSVEHDHPHALEFLRKDC 120
Query: 362 ANVNDFFMRHSVAVMTVRELFEFVTDPSITHENMDAYLSKAMEIASQRTKEERSSQDHVD 421
ANVNDFFMRHSVAVMTVRELFEFVTDPSITHENMDAYLSKAMEIASQRTKEERSSQDHVD
Sbjct: 121 ANVNDFFMRHSVAVMTVRELFEFVTDPSITHENMDAYLSKAMEIASQRTKEERSSQDHVD 180
Query: 422 EEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQK 481
EEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQK
Sbjct: 181 EEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQK 240
Query: 482 VPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEA 541
VPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEA
Sbjct: 241 VPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEA 300
Query: 542 QREKRKNKIPKHVKKRKEKTAKTKKGK 568
QREKRKNKIPKHVKKRKEKTAKTKKGK
Sbjct: 301 QREKRKNKIPKHVKKRKEKTAKTKKGK 327
>gi|22325377 sudD suppressor of bimD6 homolog [Homo sapiens]
Length = 519
Score = 274 bits (701), Expect = 1e-73
Identities = 156/438 (35%), Positives = 257/438 (58%), Gaps = 26/438 (5%)
Query: 6 LLMSRVVPGQFDDADSSDSENRDLK-TVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYD 64
L++++++ ++D + + K K I FE+ + V+ + + ++E + D
Sbjct: 78 LMLAQMLQMEYDREYDAQLRREEKKFNGDSKVSISFENYR-KVHPYEDSDSSEDEVDWQD 136
Query: 65 DDDDDWDWDEGVGKLAKGYVWNGGSNPQANRQT--SDSSSAKMSTPADKVLRKFENKINL 122
DD + + V KG++ G + + ++A+M A + + + I +
Sbjct: 137 TRDDPYRPAKPVPTPKKGFIGKGKDITTKHDEVVCGRKNTARMENFAPEF--QVGDGIGM 194
Query: 123 DKLNVTDSVINKVTEKSRQKEADMYRIKDKADRATVEQVLDPRTRMILFKMLTRGIITEI 182
D L +++ V N + + + +E R+ +K + +T E+ +DP+TR++++KM+ G++ I
Sbjct: 195 D-LKLSNHVFNALKQHAYSEERRSARLHEKKEHSTAEKAVDPKTRLLMYKMVNSGMLETI 253
Query: 183 NGCISTGKEANVYHASTANGESR-----------AIKIYKTSILVFKDRDKYVSGEFRFR 231
GCISTGKE+ V+HA + E AIK++KT++ FK+RDKY+ +FRF+
Sbjct: 254 TGCISTGKESVVFHAYGGSMEDEKEDSKVIPTECAIKVFKTTLNEFKNRDKYIKDDFRFK 313
Query: 232 HGYCKGNPRKMVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLK 291
+ K NPRK+++ WAEKEM NL R+ A IPCP ++L+ H+LVMSFIG D +PAP LK
Sbjct: 314 DRFSKLNPRKIIRMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLK 373
Query: 292 NVQLSESKARELYLQVIQYMRRMYQDARLVHADLSEFNMLYHGGGVYIIDVSQSVEHDHP 351
V+L+ + +E Y Q + MR++Y + LVHADLSE+NML+H G V++IDVSQSVE HP
Sbjct: 374 EVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLWHAGKVWLIDVSQSVEPTHP 433
Query: 352 HALEFLRKDCANVNDFFMRHSV-AVMTVRELFEFVTDPSITHENMDAYLSKAMEIASQRT 410
H LEFL +DC NV+ FF + V ++ RELF V+ +IT +N +L++ +
Sbjct: 434 HGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSGLNITADNEADFLAEIEAL----- 488
Query: 411 KEERSSQDHVDEEVFKRA 428
E+ ++DHV + K A
Sbjct: 489 --EKMNEDHVQKNGRKAA 504
>gi|229331967 RIO kinase 2 isoform 1 [Homo sapiens]
Length = 552
Score = 61.2 bits (147), Expect = 2e-09
Identities = 51/210 (24%), Positives = 97/210 (46%), Gaps = 24/210 (11%)
Query: 168 MILFKMLTRGIITEINGCISTGKEANVYHASTANGESRAIKIYK---TSILVFKDRDKYV 224
+ L + +R ++ + + GKE+++Y + G+ A+K+++ TS K++ Y
Sbjct: 83 LALKTLSSRQVVESVGNQMGVGKESDIYIVANEEGQQFALKLHRLGRTSFRNLKNKRDY- 141
Query: 225 SGEFRFRHGYCKGNPRKMVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDD 284
+ RH + + + A KE + L + P P+PI H +VM I +
Sbjct: 142 ---HKHRHNV---SWLYLSRLSAMKEFAYMKALYERKFPVPKPIDYNRHAVVMELI--NG 193
Query: 285 MPAPLLKNVQLSES---KARELYLQVIQYMRRMYQDARLVHADLSEFNMLY-HGGGVYII 340
P + +V+ S +A EL +++ + L+H D +EFN++ + +I
Sbjct: 194 YPLCQIHHVEDPASVYDEAMELIVKLANH--------GLIHGDFNEFNLILDESDHITMI 245
Query: 341 DVSQSVEHDHPHALEFLRKDCANVNDFFMR 370
D Q V HP+A + +D + DFFM+
Sbjct: 246 DFPQMVSTSHPNAEWYFDRDVKCIKDFFMK 275
>gi|229331971 RIO kinase 2 isoform 2 [Homo sapiens]
Length = 474
Score = 61.2 bits (147), Expect = 2e-09
Identities = 51/210 (24%), Positives = 97/210 (46%), Gaps = 24/210 (11%)
Query: 168 MILFKMLTRGIITEINGCISTGKEANVYHASTANGESRAIKIYK---TSILVFKDRDKYV 224
+ L + +R ++ + + GKE+++Y + G+ A+K+++ TS K++ Y
Sbjct: 83 LALKTLSSRQVVESVGNQMGVGKESDIYIVANEEGQQFALKLHRLGRTSFRNLKNKRDY- 141
Query: 225 SGEFRFRHGYCKGNPRKMVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDD 284
+ RH + + + A KE + L + P P+PI H +VM I +
Sbjct: 142 ---HKHRHNV---SWLYLSRLSAMKEFAYMKALYERKFPVPKPIDYNRHAVVMELI--NG 193
Query: 285 MPAPLLKNVQLSES---KARELYLQVIQYMRRMYQDARLVHADLSEFNMLY-HGGGVYII 340
P + +V+ S +A EL +++ + L+H D +EFN++ + +I
Sbjct: 194 YPLCQIHHVEDPASVYDEAMELIVKLANH--------GLIHGDFNEFNLILDESDHITMI 245
Query: 341 DVSQSVEHDHPHALEFLRKDCANVNDFFMR 370
D Q V HP+A + +D + DFFM+
Sbjct: 246 DFPQMVSTSHPNAEWYFDRDVKCIKDFFMK 275
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 41.2 bits (95), Expect = 0.003
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 29/147 (19%)
Query: 13 PGQFDDADSSDS--ENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYD------ 64
PG D+ D E +++ E DD ED++D E E E E+EEEE D
Sbjct: 117 PGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCH 176
Query: 65 ----------DDDDDWDWDE----------GVGKLAKGYVWNGGSNPQANRQTSDSSSAK 104
DD+++ ++D +GK+A+ + + + N TS+S
Sbjct: 177 NTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDD 236
Query: 105 MSTPADKVLRKFENKINLDKLNVTDSV 131
S + + RK E ++LD V ++V
Sbjct: 237 -SDKNENLGRKSELSLDLDSDVVRETV 262
Score = 30.8 bits (68), Expect = 3.5
Identities = 22/64 (34%), Positives = 36/64 (56%), Gaps = 6/64 (9%)
Query: 17 DDADSSD-SENRDLKTVKEKDDILFEDLQ----DNVNENGEGEIEDE-EEEGYDDDDDDW 70
D+ D SD +E+ D K E ++ ++ + D +E G+ E E+E EEE DDD+D
Sbjct: 88 DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGE 147
Query: 71 DWDE 74
D ++
Sbjct: 148 DVED 151
Score = 30.4 bits (67), Expect = 4.5
Identities = 14/58 (24%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Query: 17 DDADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWDWDE 74
D+ + D + D + +E+++ + E+ +D+ +E+GE ++EEEE ++++++ + +E
Sbjct: 113 DNDEPGDEDEEDEEGDREEEEEIEEEDEDD-DEDGEDVEDEEEEEEEEEEEEEEEENE 169
Score = 30.0 bits (66), Expect = 5.9
Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 11/67 (16%)
Query: 19 ADSSDSENRD----LKTVKEKDDILFEDLQDNVNENG-------EGEIEDEEEEGYDDDD 67
ADSS + D + + EK++ E+ ++ +E G EG+ E+EEE +D+D
Sbjct: 82 ADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDED 141
Query: 68 DDWDWDE 74
DD D ++
Sbjct: 142 DDEDGED 148
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 40.4 bits (93), Expect = 0.004
Identities = 25/68 (36%), Positives = 38/68 (55%), Gaps = 8/68 (11%)
Query: 17 DDADSSDSENRDLKTVKEKDDILFEDLQDNVNENG--EGEIEDEEEEGYDDDDDDWDWDE 74
+D ++ DSE D + E D+ ++ NE G EG E+EEEE +D+D+D D DE
Sbjct: 151 EDNEAPDSEEEDDEDGDEDDE------EEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 204
Query: 75 GVGKLAKG 82
+L +G
Sbjct: 205 AGSELGEG 212
Score = 29.6 bits (65), Expect = 7.8
Identities = 27/142 (19%), Positives = 57/142 (40%), Gaps = 8/142 (5%)
Query: 21 SSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWDWDEGVGKLA 80
S D N ++ +++ + +FE LQ +G + ++E + ++DD+D D D+ +
Sbjct: 117 SLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEEN 176
Query: 81 KGYVWNGGSNPQANRQTSDSSSAKMSTPADKVLRKFENKINLDKL--------NVTDSVI 132
+ G + + D + A L + E ++ L L D +
Sbjct: 177 EAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYV 236
Query: 133 NKVTEKSRQKEADMYRIKDKAD 154
+ E+ ++E + K K D
Sbjct: 237 EEGEEEEEEEEGGLRGEKRKRD 258
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 40.4 bits (93), Expect = 0.004
Identities = 25/68 (36%), Positives = 38/68 (55%), Gaps = 8/68 (11%)
Query: 17 DDADSSDSENRDLKTVKEKDDILFEDLQDNVNENG--EGEIEDEEEEGYDDDDDDWDWDE 74
+D ++ DSE D + E D+ ++ NE G EG E+EEEE +D+D+D D DE
Sbjct: 110 EDNEAPDSEEEDDEDGDEDDE------EEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 163
Query: 75 GVGKLAKG 82
+L +G
Sbjct: 164 AGSELGEG 171
Score = 29.6 bits (65), Expect = 7.8
Identities = 27/142 (19%), Positives = 57/142 (40%), Gaps = 8/142 (5%)
Query: 21 SSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWDWDEGVGKLA 80
S D N ++ +++ + +FE LQ +G + ++E + ++DD+D D D+ +
Sbjct: 76 SLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEEN 135
Query: 81 KGYVWNGGSNPQANRQTSDSSSAKMSTPADKVLRKFENKINLDKL--------NVTDSVI 132
+ G + + D + A L + E ++ L L D +
Sbjct: 136 EAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYV 195
Query: 133 NKVTEKSRQKEADMYRIKDKAD 154
+ E+ ++E + K K D
Sbjct: 196 EEGEEEEEEEEGGLRGEKRKRD 217
>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 3 [Homo sapiens]
Length = 220
Score = 40.4 bits (93), Expect = 0.004
Identities = 25/68 (36%), Positives = 38/68 (55%), Gaps = 8/68 (11%)
Query: 17 DDADSSDSENRDLKTVKEKDDILFEDLQDNVNENG--EGEIEDEEEEGYDDDDDDWDWDE 74
+D ++ DSE D + E D+ ++ NE G EG E+EEEE +D+D+D D DE
Sbjct: 103 EDNEAPDSEEEDDEDGDEDDE------EEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 156
Query: 75 GVGKLAKG 82
+L +G
Sbjct: 157 AGSELGEG 164
Score = 29.6 bits (65), Expect = 7.8
Identities = 27/142 (19%), Positives = 57/142 (40%), Gaps = 8/142 (5%)
Query: 21 SSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWDWDEGVGKLA 80
S D N ++ +++ + +FE LQ +G + ++E + ++DD+D D D+ +
Sbjct: 69 SLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEEN 128
Query: 81 KGYVWNGGSNPQANRQTSDSSSAKMSTPADKVLRKFENKINLDKL--------NVTDSVI 132
+ G + + D + A L + E ++ L L D +
Sbjct: 129 EAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYV 188
Query: 133 NKVTEKSRQKEADMYRIKDKAD 154
+ E+ ++E + K K D
Sbjct: 189 EEGEEEEEEEEGGLRGEKRKRD 210
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 40.4 bits (93), Expect = 0.004
Identities = 42/170 (24%), Positives = 66/170 (38%), Gaps = 21/170 (12%)
Query: 408 QRTKEERSSQDHVDEEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQ 467
Q+ K E S++D +D + + + ++ K K+E + +D+IL +
Sbjct: 5 QKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKG---KKKKEKKKQDFDEDDILKE 61
Query: 468 T------VTGLKKDLSGVQKVPALLENQVEERTCSDSEDIGSS----ECSDTDSEEQGDH 517
G+K D V P EN EE T D + G D DSEE D
Sbjct: 62 LEELSLEAQGIKADRETVAVKPT--ENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDK 119
Query: 518 ARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKKG 567
K T P ++ M + + NK+PK K + +K+ K G
Sbjct: 120 DSKSKKTAKPKVE------MYSGSDDDDDFNKLPKKAKGKAQKSNKKWDG 163
Score = 33.9 bits (76), Expect = 0.41
Identities = 38/152 (25%), Positives = 63/152 (41%), Gaps = 23/152 (15%)
Query: 421 DEEVFKRAYIPRTLNEVKNYER-----DMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKD 475
D+ FK + + E K ER + + KLKE++ + TG K
Sbjct: 219 DDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKE------------ELETGKKDQ 266
Query: 476 LSGVQKVPALLENQVEERTCSDSEDI-GSSECSDTDSEEQGDHARPKKHTTDPDIDKKER 534
+ E V+ + D+ I S E ++T + + D+ KK DKK++
Sbjct: 267 SKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKK-----DKKKK 321
Query: 535 KKMVKEAQREKRKNKIPKHVKKRKEKTAKTKK 566
K +E ++EK+K VK +E AK K+
Sbjct: 322 KGEKEEKEKEKKKGPSKATVKAMQEALAKLKE 353
Score = 32.7 bits (73), Expect = 0.92
Identities = 46/201 (22%), Positives = 85/201 (42%), Gaps = 30/201 (14%)
Query: 11 VVPGQFDDADSSDSENRD-LKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDDD 69
V P + +D + + ++ + + + +E + + + V EN E E E+EEEE D++ ++
Sbjct: 490 VEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEE 549
Query: 70 WDWDEGVGKLAKGYVWNGGSNPQANRQTSDSSSAKMSTPADKVLRKFENKINLDKLNVTD 129
+ +EG + G + + + SD + K L K +K + + D
Sbjct: 550 EEEEEGESE--------GSEGDEEDEKVSDEKD------SGKTLDKKPSK-EMSSDSEYD 594
Query: 130 SVINKVTEKSRQKEADMYRIKDKADRATVEQVLDPRTRMILFKMLTRGIITEINGCISTG 189
S + R KE Y DKA R ++ L+ + K+ R I + G + TG
Sbjct: 595 S------DDDRTKEERAY---DKAKRRIEKRRLEHSKNVNTEKL--RAPIICVLGHVDTG 643
Query: 190 KEA---NVYHASTANGESRAI 207
K + H +GE+ I
Sbjct: 644 KTKILDKLRHTHVQDGEAGGI 664
>gi|31543392 peroxisome proliferator-activated receptor gamma,
coactivator 1 beta [Homo sapiens]
Length = 1023
Score = 40.0 bits (92), Expect = 0.006
Identities = 30/88 (34%), Positives = 46/88 (52%), Gaps = 7/88 (7%)
Query: 25 ENRDLKTVKEKD-DILFEDLQDNVNENGEGEI--EDEEEEGYDDDDDDWDWDEGVGKLAK 81
E DL + K + D +FED + + +GE E+EEEEG ++++DD + D GV
Sbjct: 776 EEEDLASCKSPEYDTVFED---SSSSSGESSFLPEEEEEEGEEEEEDDEEEDSGVSPTCS 832
Query: 82 GYVWNGGSNPQANRQ-TSDSSSAKMSTP 108
+ +ANRQ S S S+ S+P
Sbjct: 833 DHCPYQSPPSKANRQLCSRSRSSSGSSP 860
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 39.7 bits (91), Expect = 0.007
Identities = 20/69 (28%), Positives = 42/69 (60%), Gaps = 2/69 (2%)
Query: 15 QFDDADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWDWDE 74
Q D +++D++ +++ +E +D ED D +E+ E + +D++++ DDD+DD D ++
Sbjct: 228 QRTDEETTDNQEGSVESSEEGEDQEHED--DGEDEDDEDDDDDDDDDDDDDDEDDEDEED 285
Query: 75 GVGKLAKGY 83
G + K Y
Sbjct: 286 GEEENQKRY 294
Score = 35.0 bits (79), Expect = 0.18
Identities = 14/45 (31%), Positives = 29/45 (64%)
Query: 30 KTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWDWDE 74
K ++ D+ ++ + +V + EGE ++ E++G D+DD+D D D+
Sbjct: 225 KDIQRTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDD 269
>gi|156071452 nardilysin isoform b [Homo sapiens]
Length = 1151
Score = 39.7 bits (91), Expect = 0.007
Identities = 16/50 (32%), Positives = 34/50 (68%)
Query: 19 ADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDD 68
+D S+ E + T ++++ E+ +++ +E+ EIED++EEG+DD+D+
Sbjct: 128 SDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDE 177
>gi|156071450 nardilysin isoform a [Homo sapiens]
Length = 1219
Score = 39.7 bits (91), Expect = 0.007
Identities = 16/50 (32%), Positives = 34/50 (68%)
Query: 19 ADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDD 68
+D S+ E + T ++++ E+ +++ +E+ EIED++EEG+DD+D+
Sbjct: 128 SDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDE 177
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 39.7 bits (91), Expect = 0.007
Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 11/97 (11%)
Query: 12 VPGQFDDADSSDSENRDLKTVKEKDDILFE--DLQDNVNENGEGEIEDEEEEGYDDDDDD 69
+P D DS++ E D + E+DD E D Q + N E + E EEE DDDD D
Sbjct: 598 IPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEE--DDDDKD 655
Query: 70 WDWDEGVGKLAKGYVWNGGSNPQANRQTSDSSSAKMS 106
D + + K ++ + N+ TS S MS
Sbjct: 656 QDESDSDTEGEK-------TSMKLNKTTSSVKSPSMS 685
Score = 30.8 bits (68), Expect = 3.5
Identities = 25/116 (21%), Positives = 50/116 (43%), Gaps = 2/116 (1%)
Query: 432 RTLNEVKNYERDMDI-IMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQKVPALLENQV 490
R N+ ++ + +D + K+K++ A + + + +G D S + + + + +
Sbjct: 210 RKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSS-EGISSSDSDDL 268
Query: 491 EERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKR 546
EE + + I SE D+DSE + H + D K + E +EKR
Sbjct: 269 EEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKR 324
>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 39.3 bits (90), Expect = 0.010
Identities = 23/58 (39%), Positives = 35/58 (60%)
Query: 17 DDADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWDWDE 74
+D ++ DS+ + KE++D ED +D NE+GE E DEEE+ +D + D D DE
Sbjct: 171 EDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDE 228
Score = 35.8 bits (81), Expect = 0.11
Identities = 19/65 (29%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
Query: 18 DADSSDSENRDLKTVKEKD-DILFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWDWDEGV 76
D ++ D E +L +++D D+ +D +D V+E E D++E+ D+D+D+ + + G
Sbjct: 199 DXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGK 258
Query: 77 GKLAK 81
G+ K
Sbjct: 259 GENRK 263
Score = 32.7 bits (73), Expect = 0.92
Identities = 13/48 (27%), Positives = 31/48 (64%)
Query: 14 GQFDDADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEE 61
G+ ++ D + E+ D++ +KD++ E+ + ++++ + E EDE+EE
Sbjct: 205 GEEEELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEE 252
>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 39.3 bits (90), Expect = 0.010
Identities = 23/58 (39%), Positives = 35/58 (60%)
Query: 17 DDADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWDWDE 74
+D ++ DS+ + KE++D ED +D NE+GE E DEEE+ +D + D D DE
Sbjct: 171 EDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDE 228
Score = 35.8 bits (81), Expect = 0.11
Identities = 19/65 (29%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
Query: 18 DADSSDSENRDLKTVKEKD-DILFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWDWDEGV 76
D ++ D E +L +++D D+ +D +D V+E E D++E+ D+D+D+ + + G
Sbjct: 199 DXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGK 258
Query: 77 GKLAK 81
G+ K
Sbjct: 259 GENRK 263
Score = 32.7 bits (73), Expect = 0.92
Identities = 13/48 (27%), Positives = 31/48 (64%)
Query: 14 GQFDDADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEE 61
G+ ++ D + E+ D++ +KD++ E+ + ++++ + E EDE+EE
Sbjct: 205 GEEEELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEE 252
>gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]
Length = 1844
Score = 39.3 bits (90), Expect = 0.010
Identities = 32/129 (24%), Positives = 50/129 (38%), Gaps = 23/129 (17%)
Query: 433 TLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQKVPALLENQVEE 492
TLN + M+ ++E + N+L + + + S + P LL+ Q+E
Sbjct: 918 TLNSKLKSGNSAAVFMRTRKE---FTEEVRNLLLEEIRWSNPEFSLKKYFPLLLKKQIEH 974
Query: 493 RTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPK 552
+ S SEC K + D+ KE K+ + EA+ K K K P
Sbjct: 975 QVLS-------SECHS-------------KQELEADVSHKETKRKLVEAENSKSKRKKPN 1014
Query: 553 HVKKRKEKT 561
K EKT
Sbjct: 1015 EYSKNLEKT 1023
>gi|170763500 SET translocation (myeloid leukemia-associated)
isoform 1 [Homo sapiens]
Length = 290
Score = 39.3 bits (90), Expect = 0.010
Identities = 26/64 (40%), Positives = 34/64 (53%), Gaps = 9/64 (14%)
Query: 20 DSSDSENRDLKTVKEKDDI--------LFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWD 71
D SD+ +L V KDDI L D+ D E E + +DEEEEG +D D++ D
Sbjct: 208 DHSDAGADELGEVI-KDDIWPNPLQYYLVPDMDDEEGEGEEDDDDDEEEEGLEDIDEEGD 266
Query: 72 WDEG 75
DEG
Sbjct: 267 EDEG 270
Score = 32.0 bits (71), Expect = 1.6
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 9/56 (16%)
Query: 14 GQFDDADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDDD 69
G+ ++ D D E L+ + E+ D ED E E E +DE EEG +D+ +D
Sbjct: 243 GEGEEDDDDDEEEEGLEDIDEEGD---ED------EGEEDEDDDEGEEGEEDEGED 289
Score = 29.6 bits (65), Expect = 7.8
Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 32 VKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDD-DDDWDWDEG 75
V + DD E +D+ ++ E +ED +EEG +D+ ++D D DEG
Sbjct: 235 VPDMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEG 279
Score = 29.6 bits (65), Expect = 7.8
Identities = 16/37 (43%), Positives = 25/37 (67%), Gaps = 3/37 (8%)
Query: 41 EDLQDNVNENGEGEIEDE--EEEGYDDDDDDWDWDEG 75
ED D+ E G +I++E E+EG +D+DDD + +EG
Sbjct: 247 EDDDDDEEEEGLEDIDEEGDEDEGEEDEDDD-EGEEG 282
>gi|170763498 SET translocation (myeloid leukemia-associated)
isoform 2 [Homo sapiens]
Length = 277
Score = 39.3 bits (90), Expect = 0.010
Identities = 26/64 (40%), Positives = 34/64 (53%), Gaps = 9/64 (14%)
Query: 20 DSSDSENRDLKTVKEKDDI--------LFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWD 71
D SD+ +L V KDDI L D+ D E E + +DEEEEG +D D++ D
Sbjct: 195 DHSDAGADELGEVI-KDDIWPNPLQYYLVPDMDDEEGEGEEDDDDDEEEEGLEDIDEEGD 253
Query: 72 WDEG 75
DEG
Sbjct: 254 EDEG 257
Score = 32.0 bits (71), Expect = 1.6
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 9/56 (16%)
Query: 14 GQFDDADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDDD 69
G+ ++ D D E L+ + E+ D ED E E E +DE EEG +D+ +D
Sbjct: 230 GEGEEDDDDDEEEEGLEDIDEEGD---ED------EGEEDEDDDEGEEGEEDEGED 276
Score = 29.6 bits (65), Expect = 7.8
Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 32 VKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDD-DDDWDWDEG 75
V + DD E +D+ ++ E +ED +EEG +D+ ++D D DEG
Sbjct: 222 VPDMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEG 266
Score = 29.6 bits (65), Expect = 7.8
Identities = 16/37 (43%), Positives = 25/37 (67%), Gaps = 3/37 (8%)
Query: 41 EDLQDNVNENGEGEIEDE--EEEGYDDDDDDWDWDEG 75
ED D+ E G +I++E E+EG +D+DDD + +EG
Sbjct: 234 EDDDDDEEEEGLEDIDEEGDEDEGEEDEDDD-EGEEG 269
>gi|62243374 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 39.3 bits (90), Expect = 0.010
Identities = 37/156 (23%), Positives = 66/156 (42%), Gaps = 15/156 (9%)
Query: 391 THENMDAYLSKAMEIASQRTKEERSSQDHVDEEVFKRAYIPRTLNEVKNYERDMDIIMKL 450
THE + L K + + ++ R+ D E+ Y P+ ++ E D++ K+
Sbjct: 389 THEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMREAE---DMVQKV 445
Query: 451 KEEDMAMNAQQDNILYQTVTGLKKDLSGVQKVPALLENQVEERTCSDSEDIGSSECSDTD 510
M AQ L ++L G ++ +LE +++ S S+E S
Sbjct: 446 HSHSAEMEAQLSQAL--------EELGGQKQRADMLEMELKMLKSQSS----SAEQSFLF 493
Query: 511 SEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKR 546
S E+ D R K + + + E +K + EAQ E+R
Sbjct: 494 SREEADTLRLKVEELEGERSRLEEEKRMLEAQLERR 529
>gi|62243369 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 39.3 bits (90), Expect = 0.010
Identities = 37/156 (23%), Positives = 66/156 (42%), Gaps = 15/156 (9%)
Query: 391 THENMDAYLSKAMEIASQRTKEERSSQDHVDEEVFKRAYIPRTLNEVKNYERDMDIIMKL 450
THE + L K + + ++ R+ D E+ Y P+ ++ E D++ K+
Sbjct: 389 THEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMREAE---DMVQKV 445
Query: 451 KEEDMAMNAQQDNILYQTVTGLKKDLSGVQKVPALLENQVEERTCSDSEDIGSSECSDTD 510
M AQ L ++L G ++ +LE +++ S S+E S
Sbjct: 446 HSHSAEMEAQLSQAL--------EELGGQKQRADMLEMELKMLKSQSS----SAEQSFLF 493
Query: 511 SEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKR 546
S E+ D R K + + + E +K + EAQ E+R
Sbjct: 494 SREEADTLRLKVEELEGERSRLEEEKRMLEAQLERR 529
>gi|62243332 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 39.3 bits (90), Expect = 0.010
Identities = 37/156 (23%), Positives = 66/156 (42%), Gaps = 15/156 (9%)
Query: 391 THENMDAYLSKAMEIASQRTKEERSSQDHVDEEVFKRAYIPRTLNEVKNYERDMDIIMKL 450
THE + L K + + ++ R+ D E+ Y P+ ++ E D++ K+
Sbjct: 389 THEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMREAE---DMVQKV 445
Query: 451 KEEDMAMNAQQDNILYQTVTGLKKDLSGVQKVPALLENQVEERTCSDSEDIGSSECSDTD 510
M AQ L ++L G ++ +LE +++ S S+E S
Sbjct: 446 HSHSAEMEAQLSQAL--------EELGGQKQRADMLEMELKMLKSQSS----SAEQSFLF 493
Query: 511 SEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKR 546
S E+ D R K + + + E +K + EAQ E+R
Sbjct: 494 SREEADTLRLKVEELEGERSRLEEEKRMLEAQLERR 529
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 38.9 bits (89), Expect = 0.013
Identities = 25/74 (33%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 16 FDDADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWDWDEG 75
F+++D + E+ D K V++ D+ LFED D+ NE E E++ E DD D+ G
Sbjct: 673 FEESDDKEDEDADGKEVEDADEKLFED--DDSNEKLFDE-EEDSSEKLFDDSDERGTLGG 729
Query: 76 VGKLAKGYVWNGGS 89
G + +G + G S
Sbjct: 730 FGSVEEGPLSTGSS 743
Score = 35.0 bits (79), Expect = 0.18
Identities = 19/53 (35%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
Query: 19 ADSSDSENRDLKTVK-EKDDILFEDLQDNVNENGEG-EIEDEEEEGYDDDDDD 69
AD E D K + + D+ LFE+ D +E+ +G E+ED +E+ ++DDD +
Sbjct: 651 ADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSN 703
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 38.9 bits (89), Expect = 0.013
Identities = 25/74 (33%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 16 FDDADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWDWDEG 75
F+++D + E+ D K V++ D+ LFED D+ NE E E++ E DD D+ G
Sbjct: 673 FEESDDKEDEDADGKEVEDADEKLFED--DDSNEKLFDE-EEDSSEKLFDDSDERGTLGG 729
Query: 76 VGKLAKGYVWNGGS 89
G + +G + G S
Sbjct: 730 FGSVEEGPLSTGSS 743
Score = 35.0 bits (79), Expect = 0.18
Identities = 19/53 (35%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
Query: 19 ADSSDSENRDLKTVK-EKDDILFEDLQDNVNENGEG-EIEDEEEEGYDDDDDD 69
AD E D K + + D+ LFE+ D +E+ +G E+ED +E+ ++DDD +
Sbjct: 651 ADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSN 703
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 38.9 bits (89), Expect = 0.013
Identities = 23/85 (27%), Positives = 41/85 (48%)
Query: 17 DDADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWDWDEGV 76
DD + D E+ D + +++ ED D+ + E E ED +E DD+D+D D D+
Sbjct: 643 DDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDE 702
Query: 77 GKLAKGYVWNGGSNPQANRQTSDSS 101
+ + + S+ + SDS+
Sbjct: 703 DEDNESEGSSSSSSSSGDSSDSDSN 727
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 38.9 bits (89), Expect = 0.013
Identities = 23/85 (27%), Positives = 41/85 (48%)
Query: 17 DDADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWDWDEGV 76
DD + D E+ D + +++ ED D+ + E E ED +E DD+D+D D D+
Sbjct: 643 DDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDE 702
Query: 77 GKLAKGYVWNGGSNPQANRQTSDSS 101
+ + + S+ + SDS+
Sbjct: 703 DEDNESEGSSSSSSSSGDSSDSDSN 727
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 38.9 bits (89), Expect = 0.013
Identities = 23/85 (27%), Positives = 41/85 (48%)
Query: 17 DDADSSDSENRDLKTVKEKDDILFEDLQDNVNENGEGEIEDEEEEGYDDDDDDWDWDEGV 76
DD + D E+ D + +++ ED D+ + E E ED +E DD+D+D D D+
Sbjct: 680 DDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDE 739
Query: 77 GKLAKGYVWNGGSNPQANRQTSDSS 101
+ + + S+ + SDS+
Sbjct: 740 DEDNESEGSSSSSSSSGDSSDSDSN 764
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 38.5 bits (88), Expect = 0.017
Identities = 52/262 (19%), Positives = 103/262 (39%), Gaps = 43/262 (16%)
Query: 341 DVSQSVEHDHPHALE-FLRKDCANVNDFFMRHSVAVMTVRELFEFVTDPSITHENMDAYL 399
++ +SVE D E F + D D F+ +T+ + + + + ++
Sbjct: 661 ELQRSVEFDREFWKENFFKSD--ETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHV 718
Query: 400 SKAMEIASQRTKEERSSQDHVDEEVFKRAYIPRTLNEVKNYERDMD-------------- 445
SK +R K ++ S E+ F+ I E +N D D
Sbjct: 719 SKERNFKEERDKIKKES-----EKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEES 773
Query: 446 IIMKLKEEDMAMNAQQDNILYQTVTGLK------KDLSGVQKVPALLENQVEERTCSDSE 499
I + L E+++ + Q+ +I K KD+ +++ E +++ S+ +
Sbjct: 774 IGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKD 833
Query: 500 DIGSSECSDTDSEE-------------QGDHARPKKHTTDPDIDKKERKKMVKEAQREKR 546
+ SEC D E+ +G+ ++ D +K R+KM ++ +EK
Sbjct: 834 KLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKP 893
Query: 547 KNKIPKHVKKRKEKTAKTKKGK 568
+ + +H+ + KEK KK K
Sbjct: 894 EKE--RHLAESKEKHLMEKKNK 913
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 38.5 bits (88), Expect = 0.017
Identities = 52/262 (19%), Positives = 103/262 (39%), Gaps = 43/262 (16%)
Query: 341 DVSQSVEHDHPHALE-FLRKDCANVNDFFMRHSVAVMTVRELFEFVTDPSITHENMDAYL 399
++ +SVE D E F + D D F+ +T+ + + + + ++
Sbjct: 684 ELQRSVEFDREFWKENFFKSD--ETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHV 741
Query: 400 SKAMEIASQRTKEERSSQDHVDEEVFKRAYIPRTLNEVKNYERDMD-------------- 445
SK +R K ++ S E+ F+ I E +N D D
Sbjct: 742 SKERNFKEERDKIKKES-----EKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEES 796
Query: 446 IIMKLKEEDMAMNAQQDNILYQTVTGLK------KDLSGVQKVPALLENQVEERTCSDSE 499
I + L E+++ + Q+ +I K KD+ +++ E +++ S+ +
Sbjct: 797 IGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKD 856
Query: 500 DIGSSECSDTDSEE-------------QGDHARPKKHTTDPDIDKKERKKMVKEAQREKR 546
+ SEC D E+ +G+ ++ D +K R+KM ++ +EK
Sbjct: 857 KLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKP 916
Query: 547 KNKIPKHVKKRKEKTAKTKKGK 568
+ + +H+ + KEK KK K
Sbjct: 917 EKE--RHLAESKEKHLMEKKNK 936
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,626,680
Number of Sequences: 37866
Number of extensions: 975072
Number of successful extensions: 9611
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 145
Number of HSP's successfully gapped in prelim test: 267
Number of HSP's that attempted gapping in prelim test: 6295
Number of HSP's gapped (non-prelim): 2326
length of query: 568
length of database: 18,247,518
effective HSP length: 108
effective length of query: 460
effective length of database: 14,157,990
effective search space: 6512675400
effective search space used: 6512675400
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.