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Search of human proteins with 23238244
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23238244 sorting nexin 16 isoform a [Homo sapiens]
(344 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23238244 sorting nexin 16 isoform a [Homo sapiens] 686 0.0
gi|23238246 sorting nexin 16 isoform a [Homo sapiens] 686 0.0
gi|23238248 sorting nexin 16 isoform b [Homo sapiens] 611 e-175
gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [H... 96 5e-20
gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [H... 96 5e-20
gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [H... 96 5e-20
gi|31543452 PX domain containing serine/threonine kinase [Homo s... 61 1e-09
gi|23111036 sorting nexin 1 isoform c [Homo sapiens] 52 8e-07
gi|23111034 sorting nexin 1 isoform a [Homo sapiens] 52 8e-07
gi|17864088 sorting nexin 13 [Homo sapiens] 49 9e-06
gi|24797143 sorting nexin 14 isoform b [Homo sapiens] 48 1e-05
gi|24797145 sorting nexin 14 isoform a [Homo sapiens] 48 1e-05
gi|154091028 sorting nexin 29 [Homo sapiens] 48 1e-05
gi|23111032 sorting nexin 1 isoform b [Homo sapiens] 46 4e-05
gi|23111038 sorting nexin 2 [Homo sapiens] 43 4e-04
gi|23111055 sorting nexin 7 isoform b [Homo sapiens] 43 5e-04
gi|194294540 sorting nexin 7 isoform a [Homo sapiens] 43 5e-04
gi|55770834 centromere protein F [Homo sapiens] 43 5e-04
gi|4507145 sorting nexin 4 [Homo sapiens] 42 8e-04
gi|157502171 sorting nexin 19 [Homo sapiens] 42 8e-04
gi|224177511 sorting nexin 18 isoform c [Homo sapiens] 42 0.001
gi|157057545 sorting nexin 18 isoform a [Homo sapiens] 42 0.001
gi|157057543 sorting nexin 18 isoform b [Homo sapiens] 42 0.001
gi|23397574 sorting nexin 33 [Homo sapiens] 42 0.001
gi|66472382 nischarin [Homo sapiens] 40 0.002
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 39 0.007
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 39 0.007
gi|153791707 sorting nexin family member 30 [Homo sapiens] 39 0.007
gi|15553099 sorting nexin 21 isoform a [Homo sapiens] 39 0.007
gi|169217383 PREDICTED: similar to coiled-coil domain containing... 38 0.012
>gi|23238244 sorting nexin 16 isoform a [Homo sapiens]
Length = 344
Score = 686 bits (1769), Expect = 0.0
Identities = 344/344 (100%), Positives = 344/344 (100%)
Query: 1 MATPYVPVPMPIGNSASSFTTNRNQRSSSFGSVSTSSNSSKGQLEDSNMGNFKQTSVPDQ 60
MATPYVPVPMPIGNSASSFTTNRNQRSSSFGSVSTSSNSSKGQLEDSNMGNFKQTSVPDQ
Sbjct: 1 MATPYVPVPMPIGNSASSFTTNRNQRSSSFGSVSTSSNSSKGQLEDSNMGNFKQTSVPDQ 60
Query: 61 MDNTSSVCSSPLIRTKFTGTASSIEYSTRPRDTEEQNPETVNWEDRPSTPTILGYEVMEE 120
MDNTSSVCSSPLIRTKFTGTASSIEYSTRPRDTEEQNPETVNWEDRPSTPTILGYEVMEE
Sbjct: 61 MDNTSSVCSSPLIRTKFTGTASSIEYSTRPRDTEEQNPETVNWEDRPSTPTILGYEVMEE 120
Query: 121 RAKFTVYKILVKKTPEESWVVFRRYTDFSRLNDKLKEMFPGFRLALPPKRWFKDNYNADF 180
RAKFTVYKILVKKTPEESWVVFRRYTDFSRLNDKLKEMFPGFRLALPPKRWFKDNYNADF
Sbjct: 121 RAKFTVYKILVKKTPEESWVVFRRYTDFSRLNDKLKEMFPGFRLALPPKRWFKDNYNADF 180
Query: 181 LEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGPFDSLEESRAFCETLEETNYRL 240
LEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGPFDSLEESRAFCETLEETNYRL
Sbjct: 181 LEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGPFDSLEESRAFCETLEETNYRL 240
Query: 241 QKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESLDVSETEGEQILKVESSA 300
QKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESLDVSETEGEQILKVESSA
Sbjct: 241 QKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESLDVSETEGEQILKVESSA 300
Query: 301 LEVDQDVLDEESRADNKPCLSFSEPENAVSEIEVAEVAYDAEED 344
LEVDQDVLDEESRADNKPCLSFSEPENAVSEIEVAEVAYDAEED
Sbjct: 301 LEVDQDVLDEESRADNKPCLSFSEPENAVSEIEVAEVAYDAEED 344
>gi|23238246 sorting nexin 16 isoform a [Homo sapiens]
Length = 344
Score = 686 bits (1769), Expect = 0.0
Identities = 344/344 (100%), Positives = 344/344 (100%)
Query: 1 MATPYVPVPMPIGNSASSFTTNRNQRSSSFGSVSTSSNSSKGQLEDSNMGNFKQTSVPDQ 60
MATPYVPVPMPIGNSASSFTTNRNQRSSSFGSVSTSSNSSKGQLEDSNMGNFKQTSVPDQ
Sbjct: 1 MATPYVPVPMPIGNSASSFTTNRNQRSSSFGSVSTSSNSSKGQLEDSNMGNFKQTSVPDQ 60
Query: 61 MDNTSSVCSSPLIRTKFTGTASSIEYSTRPRDTEEQNPETVNWEDRPSTPTILGYEVMEE 120
MDNTSSVCSSPLIRTKFTGTASSIEYSTRPRDTEEQNPETVNWEDRPSTPTILGYEVMEE
Sbjct: 61 MDNTSSVCSSPLIRTKFTGTASSIEYSTRPRDTEEQNPETVNWEDRPSTPTILGYEVMEE 120
Query: 121 RAKFTVYKILVKKTPEESWVVFRRYTDFSRLNDKLKEMFPGFRLALPPKRWFKDNYNADF 180
RAKFTVYKILVKKTPEESWVVFRRYTDFSRLNDKLKEMFPGFRLALPPKRWFKDNYNADF
Sbjct: 121 RAKFTVYKILVKKTPEESWVVFRRYTDFSRLNDKLKEMFPGFRLALPPKRWFKDNYNADF 180
Query: 181 LEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGPFDSLEESRAFCETLEETNYRL 240
LEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGPFDSLEESRAFCETLEETNYRL
Sbjct: 181 LEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGPFDSLEESRAFCETLEETNYRL 240
Query: 241 QKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESLDVSETEGEQILKVESSA 300
QKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESLDVSETEGEQILKVESSA
Sbjct: 241 QKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESLDVSETEGEQILKVESSA 300
Query: 301 LEVDQDVLDEESRADNKPCLSFSEPENAVSEIEVAEVAYDAEED 344
LEVDQDVLDEESRADNKPCLSFSEPENAVSEIEVAEVAYDAEED
Sbjct: 301 LEVDQDVLDEESRADNKPCLSFSEPENAVSEIEVAEVAYDAEED 344
>gi|23238248 sorting nexin 16 isoform b [Homo sapiens]
Length = 315
Score = 611 bits (1576), Expect = e-175
Identities = 315/344 (91%), Positives = 315/344 (91%), Gaps = 29/344 (8%)
Query: 1 MATPYVPVPMPIGNSASSFTTNRNQRSSSFGSVSTSSNSSKGQLEDSNMGNFKQTSVPDQ 60
MATPYVPVPMPIGNSASSFTTNRNQRSSSFGSVSTSSNSSKGQLEDSNMGNFKQTSVPDQ
Sbjct: 1 MATPYVPVPMPIGNSASSFTTNRNQRSSSFGSVSTSSNSSKGQLEDSNMGNFKQTSVPDQ 60
Query: 61 MDNTSSVCSSPLIRTKFTGTASSIEYSTRPRDTEEQNPETVNWEDRPSTPTILGYEVMEE 120
MDNTSSVCSSPLIRTKFTGTASSIEYSTRPRDTEEQNPETVNWEDRPSTPTILGYEVMEE
Sbjct: 61 MDNTSSVCSSPLIRTKFTGTASSIEYSTRPRDTEEQNPETVNWEDRPSTPTILGYEVMEE 120
Query: 121 RAKFTVYKILVKKTPEESWVVFRRYTDFSRLNDKLKEMFPGFRLALPPKRWFKDNYNADF 180
RAKFT LKEMFPGFRLALPPKRWFKDNYNADF
Sbjct: 121 RAKFT-----------------------------LKEMFPGFRLALPPKRWFKDNYNADF 151
Query: 181 LEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGPFDSLEESRAFCETLEETNYRL 240
LEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGPFDSLEESRAFCETLEETNYRL
Sbjct: 152 LEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGPFDSLEESRAFCETLEETNYRL 211
Query: 241 QKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESLDVSETEGEQILKVESSA 300
QKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESLDVSETEGEQILKVESSA
Sbjct: 212 QKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESLDVSETEGEQILKVESSA 271
Query: 301 LEVDQDVLDEESRADNKPCLSFSEPENAVSEIEVAEVAYDAEED 344
LEVDQDVLDEESRADNKPCLSFSEPENAVSEIEVAEVAYDAEED
Sbjct: 272 LEVDQDVLDEESRADNKPCLSFSEPENAVSEIEVAEVAYDAEED 315
>gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [Homo
sapiens]
Length = 464
Score = 95.9 bits (237), Expect = 5e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 2/131 (1%)
Query: 96 QNPETVNWEDR-PSTPTILGYEVMEERAKFTVYKILVKKTPEESWVVFRRYTDFSRLNDK 154
Q T+++++ PS E E++ +FTVYK+LV E W VFRRY +F +L +
Sbjct: 2 QRDHTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSE-WFVFRRYAEFDKLYNT 60
Query: 155 LKEMFPGFRLALPPKRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLD 214
LK+ FP L +P KR F DN++ DF++ R+ GL F+QNLV + ++ N VR FL +D
Sbjct: 61 LKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMD 120
Query: 215 DPPGPFDSLEE 225
P D E+
Sbjct: 121 SPKHQSDPSED 131
>gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
sapiens]
Length = 496
Score = 95.9 bits (237), Expect = 5e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 2/131 (1%)
Query: 96 QNPETVNWEDR-PSTPTILGYEVMEERAKFTVYKILVKKTPEESWVVFRRYTDFSRLNDK 154
Q T+++++ PS E E++ +FTVYK+LV E W VFRRY +F +L +
Sbjct: 2 QRDHTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSE-WFVFRRYAEFDKLYNT 60
Query: 155 LKEMFPGFRLALPPKRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLD 214
LK+ FP L +P KR F DN++ DF++ R+ GL F+QNLV + ++ N VR FL +D
Sbjct: 61 LKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMD 120
Query: 215 DPPGPFDSLEE 225
P D E+
Sbjct: 121 SPKHQSDPSED 131
>gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
sapiens]
Length = 496
Score = 95.9 bits (237), Expect = 5e-20
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 2/131 (1%)
Query: 96 QNPETVNWEDR-PSTPTILGYEVMEERAKFTVYKILVKKTPEESWVVFRRYTDFSRLNDK 154
Q T+++++ PS E E++ +FTVYK+LV E W VFRRY +F +L +
Sbjct: 2 QRDHTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSE-WFVFRRYAEFDKLYNT 60
Query: 155 LKEMFPGFRLALPPKRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLD 214
LK+ FP L +P KR F DN++ DF++ R+ GL F+QNLV + ++ N VR FL +D
Sbjct: 61 LKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMD 120
Query: 215 DPPGPFDSLEE 225
P D E+
Sbjct: 121 SPKHQSDPSED 131
>gi|31543452 PX domain containing serine/threonine kinase [Homo
sapiens]
Length = 578
Score = 61.2 bits (147), Expect = 1e-09
Identities = 36/106 (33%), Positives = 57/106 (53%), Gaps = 5/106 (4%)
Query: 108 STPTILGYEVMEERAKFTVYKILVKK--TPEESWVVFRRYTDFSRLNDKLKEMFPGFRLA 165
+ P E + T Y I V++ + E SW + RRY+DF LN+ L+ G L
Sbjct: 17 TVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSLQ--IAGLSLP 74
Query: 166 LPPKRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFL 211
LPPK+ N + +F+ +RQ GLQ +L + + ++NC V++FL
Sbjct: 75 LPPKKLI-GNMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFL 119
>gi|23111036 sorting nexin 1 isoform c [Homo sapiens]
Length = 474
Score = 52.0 bits (123), Expect = 8e-07
Identities = 57/254 (22%), Positives = 111/254 (43%), Gaps = 28/254 (11%)
Query: 52 FKQTSVPDQMDNTSSVCSSPLIRTKFTGTASSIEYSTRPRDTEEQNPETVNWEDRPSTPT 111
F +V +D+T + L +T + S++P+ T E+ E + T
Sbjct: 89 FADATVELSLDSTQNNQKKVLAKTLISLPPQEATNSSKPQPTYEELEEEEQEDQFDLTVG 148
Query: 112 ILGYEVMEERAK-FTVYKILVKKT----PEESWVVFRRYTDFSRLNDKLKEMFP--GFRL 164
I E + + + YK+ + + + + V RR++DF L +KL E GF +
Sbjct: 149 ITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIV 208
Query: 165 ALPPKRWF----------KDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLD 214
PP++ +D+ +A+FLE R+ L+ +LQ +V H + VREFL +
Sbjct: 209 PPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKE 268
Query: 215 DPPGPFDS--------LEESRAFCETLEETNYRLQKELL---EKQKEMESLKKLLSEKQL 263
+ P + L+ + + + ++ + + EK +E+E ++ L +
Sbjct: 269 ELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHA 328
Query: 264 HIDTLENRIRTLSL 277
++TL N + L+L
Sbjct: 329 VVETLVNHRKELAL 342
>gi|23111034 sorting nexin 1 isoform a [Homo sapiens]
Length = 522
Score = 52.0 bits (123), Expect = 8e-07
Identities = 57/254 (22%), Positives = 111/254 (43%), Gaps = 28/254 (11%)
Query: 52 FKQTSVPDQMDNTSSVCSSPLIRTKFTGTASSIEYSTRPRDTEEQNPETVNWEDRPSTPT 111
F +V +D+T + L +T + S++P+ T E+ E + T
Sbjct: 89 FADATVELSLDSTQNNQKKVLAKTLISLPPQEATNSSKPQPTYEELEEEEQEDQFDLTVG 148
Query: 112 ILGYEVMEERAK-FTVYKILVKKT----PEESWVVFRRYTDFSRLNDKLKEMFP--GFRL 164
I E + + + YK+ + + + + V RR++DF L +KL E GF +
Sbjct: 149 ITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIV 208
Query: 165 ALPPKRWF----------KDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLD 214
PP++ +D+ +A+FLE R+ L+ +LQ +V H + VREFL +
Sbjct: 209 PPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKE 268
Query: 215 DPPGPFDS--------LEESRAFCETLEETNYRLQKELL---EKQKEMESLKKLLSEKQL 263
+ P + L+ + + + ++ + + EK +E+E ++ L +
Sbjct: 269 ELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHA 328
Query: 264 HIDTLENRIRTLSL 277
++TL N + L+L
Sbjct: 329 VVETLVNHRKELAL 342
>gi|17864088 sorting nexin 13 [Homo sapiens]
Length = 957
Score = 48.5 bits (114), Expect = 9e-06
Identities = 30/79 (37%), Positives = 44/79 (55%), Gaps = 6/79 (7%)
Query: 124 FTVYKILVKK---TPEESWVVFRRYTDFSRLNDKLKEMFPGFR--LALPPKRWFKDNYNA 178
+ +Y I V + EE W +RRY+DF + ++ E F L LP K+ F +N +
Sbjct: 578 YALYAITVHRRNLNSEEMWKTYRRYSDFHDFHMRITEQFESLSSILKLPGKKTF-NNMDR 636
Query: 179 DFLEDRQLGLQAFLQNLVA 197
DFLE R+ L A+LQ L+A
Sbjct: 637 DFLEKRKKDLNAYLQLLLA 655
>gi|24797143 sorting nexin 14 isoform b [Homo sapiens]
Length = 893
Score = 47.8 bits (112), Expect = 1e-05
Identities = 30/103 (29%), Positives = 50/103 (48%), Gaps = 7/103 (6%)
Query: 116 EVMEERAKFTVYKILVKKTPE-------ESWVVFRRYTDFSRLNDKLKEMFPGFRLALPP 168
E E++ + V+ I V++ E W V+RRY +F L KL E F A P
Sbjct: 528 ERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLP 587
Query: 169 KRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFL 211
+ N +FL+ ++ Q +LQ L+ H +++N + +FL
Sbjct: 588 SKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFL 630
>gi|24797145 sorting nexin 14 isoform a [Homo sapiens]
Length = 946
Score = 47.8 bits (112), Expect = 1e-05
Identities = 30/103 (29%), Positives = 50/103 (48%), Gaps = 7/103 (6%)
Query: 116 EVMEERAKFTVYKILVKKTPE-------ESWVVFRRYTDFSRLNDKLKEMFPGFRLALPP 168
E E++ + V+ I V++ E W V+RRY +F L KL E F A P
Sbjct: 581 ERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLP 640
Query: 169 KRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFL 211
+ N +FL+ ++ Q +LQ L+ H +++N + +FL
Sbjct: 641 SKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFL 683
>gi|154091028 sorting nexin 29 [Homo sapiens]
Length = 428
Score = 47.8 bits (112), Expect = 1e-05
Identities = 26/74 (35%), Positives = 47/74 (63%), Gaps = 3/74 (4%)
Query: 124 FTVYKILVKKTPEESWVVFRRYTDFSRLNDKLKEMFPGFR-LALPPKRWFKDNYNADFLE 182
F VY++ ++ +E W ++RRYT+F L+ KL+ +P R PPK+ N +A F+E
Sbjct: 290 FHVYQVYIRIKDDE-WNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKAI-GNKDAKFVE 347
Query: 183 DRQLGLQAFLQNLV 196
+R+ LQ +L++++
Sbjct: 348 ERRKQLQNYLRSVM 361
>gi|23111032 sorting nexin 1 isoform b [Homo sapiens]
Length = 457
Score = 46.2 bits (108), Expect = 4e-05
Identities = 43/181 (23%), Positives = 84/181 (46%), Gaps = 27/181 (14%)
Query: 124 FTVYKILVKKT----PEESWVVFRRYTDFSRLNDKLKEMFP--GFRLALPPKRWF----- 172
+ YK+ + + + + V RR++DF L +KL E GF + PP++
Sbjct: 97 YVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTK 156
Query: 173 -----KDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGPFDS----- 222
+D+ +A+FLE R+ L+ +LQ +V H + VREFL ++ P +
Sbjct: 157 VKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKEELPRAVGTQTLSG 216
Query: 223 ---LEESRAFCETLEETNYRLQKELL---EKQKEMESLKKLLSEKQLHIDTLENRIRTLS 276
L+ + + + ++ + + EK +E+E ++ L + ++TL N + L+
Sbjct: 217 AGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELA 276
Query: 277 L 277
L
Sbjct: 277 L 277
>gi|23111038 sorting nexin 2 [Homo sapiens]
Length = 519
Score = 43.1 bits (100), Expect = 4e-04
Identities = 51/229 (22%), Positives = 93/229 (40%), Gaps = 16/229 (6%)
Query: 64 TSSVCSSPLIRTKFTGTASSIEYSTRPRDTEEQNPETVNWEDRPSTPTILGYEVMEERAK 123
T + +P I +K + +A I +R EE N + + E S P +G + A
Sbjct: 104 TPTTLIAPRIESK-SMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAY 162
Query: 124 FTVYKILVKKTPEESWVVFRRYTDFSRLNDKLKEMFPGFRLALPP------------KRW 171
K + + + V RR++DF L+ KL + +PP K
Sbjct: 163 RVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVG 222
Query: 172 FKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGPFDSLEESRAFCE 231
+D+ + +F+E R+ L+ +LQ V H + +R+FL + P ++ S A
Sbjct: 223 KEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGIL 282
Query: 232 TLEETNYRLQKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPE 280
+ ++ K E ++ EKQ + L+ ++R L + E
Sbjct: 283 RMVNKAADAVNKMTIKMNESDA---WFEEKQQQFENLDQQLRKLHVSVE 328
>gi|23111055 sorting nexin 7 isoform b [Homo sapiens]
Length = 336
Score = 42.7 bits (99), Expect = 5e-04
Identities = 59/229 (25%), Positives = 94/229 (41%), Gaps = 33/229 (14%)
Query: 124 FTVYKILVKKTPEE----SWVVFRRYTDFSRLNDKLKEMFPGFRLALPP------KRWFK 173
F Y+I+ K + E + V RRY DF L KL+E P L +PP +
Sbjct: 49 FITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHP--TLIIPPLPEKFIVKGMV 106
Query: 174 DNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLD---------DPPGPFDSLE 224
+ +N DF+E R+ L FL + H + + FL PG +
Sbjct: 107 ERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMG 166
Query: 225 ES-RAFCETLEETNYRLQKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESL 283
++ RA ++ R K E+ EM + +L S+K ID + RI E E
Sbjct: 167 QTVRAVASSM-----RGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYK---EEREYF 218
Query: 284 DVSETEGEQILKVESSALEVD-QDVLDEESRADNKPCLSFSEPENAVSE 331
D + G + + SA E D D L + + ++ C + + + +SE
Sbjct: 219 DEMKEYGP--IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSE 265
>gi|194294540 sorting nexin 7 isoform a [Homo sapiens]
Length = 451
Score = 42.7 bits (99), Expect = 5e-04
Identities = 59/229 (25%), Positives = 94/229 (41%), Gaps = 33/229 (14%)
Query: 124 FTVYKILVKKTPEE----SWVVFRRYTDFSRLNDKLKEMFPGFRLALPP------KRWFK 173
F Y+I+ K + E + V RRY DF L KL+E P L +PP +
Sbjct: 113 FITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHP--TLIIPPLPEKFIVKGMV 170
Query: 174 DNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLD---------DPPGPFDSLE 224
+ +N DF+E R+ L FL + H + + FL PG +
Sbjct: 171 ERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMG 230
Query: 225 ES-RAFCETLEETNYRLQKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESL 283
++ RA ++ R K E+ EM + +L S+K ID + RI E E
Sbjct: 231 QTVRAVASSM-----RGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYK---EEREYF 282
Query: 284 DVSETEGEQILKVESSALEVD-QDVLDEESRADNKPCLSFSEPENAVSE 331
D + G + + SA E D D L + + ++ C + + + +SE
Sbjct: 283 DEMKEYGP--IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSE 329
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 42.7 bits (99), Expect = 5e-04
Identities = 38/155 (24%), Positives = 68/155 (43%), Gaps = 27/155 (17%)
Query: 185 QLGLQAFLQNLVAHKDIANCLAVREFLCL----------DDPPGPFDSLEESRAFCE--- 231
Q G + L NL C +V E C + P P +EE + CE
Sbjct: 1502 QTGDMSLLSNLEGAVSANQC-SVDEVFCSSLQEENLTRKETPSAPAKGVEELESLCEVYR 1560
Query: 232 -TLEETNYRLQKELLEKQKEMESLKKLLSEKQLHIDTL-----------ENRIRTLSLEP 279
+LE+ +++ + + K KE++ L++LLS ++ +D L + ++ +++LE
Sbjct: 1561 QSLEKLEEKMESQGIMKNKEIQELEQLLSSERQELDCLRKQYLSENEQWQQKLTSVTLEM 1620
Query: 280 EESLDVSETEGEQILKVESSALEVDQDVLDEESRA 314
E L + + EQ L +E + LD SR+
Sbjct: 1621 ESKLAAEKKQTEQ-LSLELEVARLQLQGLDLSSRS 1654
Score = 31.2 bits (69), Expect = 1.4
Identities = 15/59 (25%), Positives = 31/59 (52%)
Query: 230 CETLEETNYRLQKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESLDVSET 288
CE+LE+T ++ EL K+ ++ + L+ + I+ LE ++ E E S +++
Sbjct: 76 CESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQS 134
Score = 30.0 bits (66), Expect = 3.2
Identities = 21/101 (20%), Positives = 50/101 (49%), Gaps = 1/101 (0%)
Query: 232 TLEETNYRLQKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESLDVSETEGE 291
TL L K++ EKQ ++ L KLLS + ++ E + E + ++++ + + +
Sbjct: 2207 TLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLK 2266
Query: 292 QILKVESSALEVDQDVLDEESRADNKPCLSFSEPENAVSEI 332
+ L +AL DQ+++ ++ + P + N++ ++
Sbjct: 2267 E-LNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKL 2306
Score = 28.9 bits (63), Expect = 7.0
Identities = 19/75 (25%), Positives = 38/75 (50%), Gaps = 8/75 (10%)
Query: 233 LEETNYRLQKELLEKQKEMES----LKKLLSEKQLHIDTLENRIRTLSLEPEESLDVSET 288
LEE L L+K +E+E LKK ++Q +D+LE ++ + ++ ++ +T
Sbjct: 5 LEEWKEGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQ----KQKQKVENEKT 60
Query: 289 EGEQILKVESSALEV 303
EG + + +E+
Sbjct: 61 EGTNLKRENQRLMEI 75
>gi|4507145 sorting nexin 4 [Homo sapiens]
Length = 450
Score = 42.0 bits (97), Expect = 8e-04
Identities = 42/144 (29%), Positives = 67/144 (46%), Gaps = 26/144 (18%)
Query: 114 GYEVMEERAKFTVYKI---LVKKTPEESWV---VFRRYTDFSRLNDKLKEMFPGFRLA-L 166
G M + +T Y I V+ T +S + ++RRY++F L L +P + L
Sbjct: 70 GRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPL 129
Query: 167 PPKR----WFK---DNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGP 219
P KR W K DN + DF+E R++GL+ FL + +H LC D
Sbjct: 130 PEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASH----------PILCRDKIFYL 179
Query: 220 FDSLEESRAFCETLEETNYRLQKE 243
F L + + ET+ ET ++L+ +
Sbjct: 180 F--LTQEGNWKETVNETGFQLKAD 201
>gi|157502171 sorting nexin 19 [Homo sapiens]
Length = 992
Score = 42.0 bits (97), Expect = 8e-04
Identities = 31/82 (37%), Positives = 46/82 (56%), Gaps = 9/82 (10%)
Query: 141 VFRRYTDFSRLNDKLKEMFPGFRLALP----PKRWFKD----NYNADFLEDRQLGLQAFL 192
V RRY +F L +L+E P R + PK+ F D N ++D +E R+ L++FL
Sbjct: 579 VNRRYREFLNLQTRLEEK-PDLRKFIKNVKGPKKLFPDLPFGNMDSDRVEARKSLLESFL 637
Query: 193 QNLVAHKDIANCLAVREFLCLD 214
+ L A +IAN V+EFL L+
Sbjct: 638 KQLCAIPEIANSEEVQEFLALN 659
>gi|224177511 sorting nexin 18 isoform c [Homo sapiens]
Length = 591
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 4/117 (3%)
Query: 98 PETVNWEDRPSTPTILGYEVMEERAKFTVYK--ILVKKTPEESWV-VFRRYTDFSRLNDK 154
P W++ P P + ++ KF K I K P + V V RRY F L +
Sbjct: 264 PYGPEWQENPY-PFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYAR 322
Query: 155 LKEMFPGFRLALPPKRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFL 211
L E FP + P++ + DF+ R+ GL ++ ++ +H +A C + FL
Sbjct: 323 LAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFL 379
>gi|157057545 sorting nexin 18 isoform a [Homo sapiens]
Length = 624
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 4/117 (3%)
Query: 98 PETVNWEDRPSTPTILGYEVMEERAKFTVYK--ILVKKTPEESWV-VFRRYTDFSRLNDK 154
P W++ P P + ++ KF K I K P + V V RRY F L +
Sbjct: 264 PYGPEWQENPY-PFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYAR 322
Query: 155 LKEMFPGFRLALPPKRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFL 211
L E FP + P++ + DF+ R+ GL ++ ++ +H +A C + FL
Sbjct: 323 LAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFL 379
>gi|157057543 sorting nexin 18 isoform b [Homo sapiens]
Length = 628
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 4/117 (3%)
Query: 98 PETVNWEDRPSTPTILGYEVMEERAKFTVYK--ILVKKTPEESWV-VFRRYTDFSRLNDK 154
P W++ P P + ++ KF K I K P + V V RRY F L +
Sbjct: 264 PYGPEWQENPY-PFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYAR 322
Query: 155 LKEMFPGFRLALPPKRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFL 211
L E FP + P++ + DF+ R+ GL ++ ++ +H +A C + FL
Sbjct: 323 LAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFL 379
>gi|23397574 sorting nexin 33 [Homo sapiens]
Length = 574
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 5/125 (4%)
Query: 95 EQNPETVNWEDRPSTPTILGYEVMEERAKFTVYK--ILVKKTPEESWV-VFRRYTDFSRL 151
E P W+ P P E ++ KF K I K TP + V+RRY F L
Sbjct: 215 EMGPRGPQWKANPH-PFACSVEDPTKQTKFKGIKSYISYKLTPTHAASPVYRRYKHFDWL 273
Query: 152 NDKLKEMFPGFRLALPPKRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFL 211
++L F + P++ + DF+E R+ L ++ ++ +H ++ + FL
Sbjct: 274 YNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFL 333
Query: 212 -CLDD 215
CLDD
Sbjct: 334 SCLDD 338
>gi|66472382 nischarin [Homo sapiens]
Length = 1504
Score = 40.4 bits (93), Expect = 0.002
Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 5/86 (5%)
Query: 112 ILGYEVMEERAKFTVYKILVKKTPEESWVVFRRYTDFSRLNDKLKEMFPGFRLALPPKRW 171
++G E+++ +TVY I V E W V RY+DF L++KL + LPPK+
Sbjct: 21 VVGSELVDT---YTVYIIQVTDGSHE-WTVKHRYSDFHDLHEKLVAERKIDKNLLPPKKI 76
Query: 172 FKDNYNADFLEDRQLGLQAFLQNLVA 197
N + +E R+ L+ +LQ L+A
Sbjct: 77 IGKN-SRSLVEKREKDLEVYLQKLLA 101
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 38.9 bits (89), Expect = 0.007
Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 2/94 (2%)
Query: 220 FDSLEESRAFCETLEETNYRLQKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEP 279
F E + L+ N RLQK L K+++ L+ L + ++ TL+ + L +
Sbjct: 748 FKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKIS- 806
Query: 280 EESLDVSETEGEQILKVESSALEVDQDVLDEESR 313
+ L+ E E + L+ E+S LE D+ L++E++
Sbjct: 807 SKRLEQLEKENKS-LEQETSQLEKDKKQLEKENK 839
Score = 35.0 bits (79), Expect = 0.098
Identities = 35/125 (28%), Positives = 55/125 (44%), Gaps = 9/125 (7%)
Query: 221 DSLEESRAFCETLEETNYRLQKELLEK---QKEMESLKKLLSEKQLHIDTLENRIRTLSL 277
D +E++ E+++ET+ +L K EK +KE+E K EK + LEN + L
Sbjct: 584 DIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK----EKGERAEELENELH--HL 637
Query: 278 EPEESLDVSETEGEQILKVESSALEVDQDVLDEESRADNKPCLSFSEPENAVSEIEVAEV 337
E E L + +I + ALE + L+ E+R K SF + +E
Sbjct: 638 EKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENS 697
Query: 338 AYDAE 342
D E
Sbjct: 698 QLDEE 702
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 38.9 bits (89), Expect = 0.007
Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 2/94 (2%)
Query: 220 FDSLEESRAFCETLEETNYRLQKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEP 279
F E + L+ N RLQK L K+++ L+ L + ++ TL+ + L +
Sbjct: 748 FKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKIS- 806
Query: 280 EESLDVSETEGEQILKVESSALEVDQDVLDEESR 313
+ L+ E E + L+ E+S LE D+ L++E++
Sbjct: 807 SKRLEQLEKENKS-LEQETSQLEKDKKQLEKENK 839
Score = 35.0 bits (79), Expect = 0.098
Identities = 35/125 (28%), Positives = 55/125 (44%), Gaps = 9/125 (7%)
Query: 221 DSLEESRAFCETLEETNYRLQKELLEK---QKEMESLKKLLSEKQLHIDTLENRIRTLSL 277
D +E++ E+++ET+ +L K EK +KE+E K EK + LEN + L
Sbjct: 584 DIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK----EKGERAEELENELH--HL 637
Query: 278 EPEESLDVSETEGEQILKVESSALEVDQDVLDEESRADNKPCLSFSEPENAVSEIEVAEV 337
E E L + +I + ALE + L+ E+R K SF + +E
Sbjct: 638 EKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENS 697
Query: 338 AYDAE 342
D E
Sbjct: 698 QLDEE 702
>gi|153791707 sorting nexin family member 30 [Homo sapiens]
Length = 437
Score = 38.9 bits (89), Expect = 0.007
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
Query: 124 FTVYKILVKKTPEE----SWVVFRRYTDFSRLNDKLKEMFPGFRLALPPKRW----FKDN 175
+ Y+I K T E + V RRY DF L KL+E P + P+++ D
Sbjct: 108 YITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVVDR 167
Query: 176 YNADFLEDRQLGLQAFLQNLVAH 198
++ +F+E R+ L FL+ + H
Sbjct: 168 FSEEFVETRRKALDKFLKRITDH 190
>gi|15553099 sorting nexin 21 isoform a [Homo sapiens]
Length = 373
Score = 38.9 bits (89), Expect = 0.007
Identities = 21/76 (27%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 141 VFRRYTDFSRLNDKLKEMFPGFRLALP-PKRWFKDNYNADFLEDRQLGLQAFLQNLVAHK 199
+ RRY+DF RL+ L+ F G A+ P++ + N+ A+ + R + FL +L A
Sbjct: 168 ISRRYSDFERLHRNLQRQFRGPMAAISFPRKRLRRNFTAETIARRSRAFEQFLGHLQAVP 227
Query: 200 DIANCLAVREFLCLDD 215
++ + +++F L +
Sbjct: 228 ELRHAPDLQDFFVLPE 243
>gi|169217383 PREDICTED: similar to coiled-coil domain containing 29
[Homo sapiens]
Length = 185
Score = 38.1 bits (87), Expect = 0.012
Identities = 36/152 (23%), Positives = 69/152 (45%), Gaps = 12/152 (7%)
Query: 193 QNLVAHKDIANCLAVREFLCLDDPPGPFDSL----EESRAFCETLEETNYRLQKELLEKQ 248
++ V H+D+ + L + FD L E + C L + N +Q+ELL +
Sbjct: 12 EDFVCHEDLKTDQLKMDIL-IKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMK 70
Query: 249 K------EMESLKKLLSEKQLHIDT-LENRIRTLSLEPEESLDVSETEGEQILKVESSAL 301
K ++E KK+L E+ L++ T +EN + LS E + E + + K+E L
Sbjct: 71 KVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHL 130
Query: 302 EVDQDVLDEESRADNKPCLSFSEPENAVSEIE 333
+++ D +++ R + + +S +E
Sbjct: 131 QMEADCVEQIIRETKRTVAVLDTCSHLLSSLE 162
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,556,425
Number of Sequences: 37866
Number of extensions: 608553
Number of successful extensions: 3753
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 115
Number of HSP's successfully gapped in prelim test: 264
Number of HSP's that attempted gapping in prelim test: 3030
Number of HSP's gapped (non-prelim): 951
length of query: 344
length of database: 18,247,518
effective HSP length: 103
effective length of query: 241
effective length of database: 14,347,320
effective search space: 3457704120
effective search space used: 3457704120
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.