BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|23238208 interleukin 17A receptor precursor [Homo sapiens] (866 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|23238208 interleukin 17A receptor precursor [Homo sapiens] 1793 0.0 gi|27477074 interleukin 17B receptor precursor [Homo sapiens] 149 1e-35 gi|166063983 interleukin 17 receptor D [Homo sapiens] 101 3e-21 gi|24430197 interleukin 17 receptor C isoform 1 precursor [Homo ... 56 2e-07 gi|90669934 interleukin 17 receptor C isoform 3 precursor [Homo ... 56 2e-07 gi|24430195 interleukin 17 receptor C isoform 2 precursor [Homo ... 56 2e-07 gi|61742808 hypothetical protein LOC283638 isoform 2 [Homo sapiens] 46 1e-04 gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo sapi... 46 1e-04 gi|5032179 tripartite motif-containing 28 protein [Homo sapiens] 41 0.004 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 41 0.005 gi|24430210 interleukin 17 receptor E isoform 1 [Homo sapiens] 40 0.009 gi|24430206 interleukin 17 receptor E isoform 2 [Homo sapiens] 40 0.009 gi|24430204 interleukin 17 receptor E isoform 1 [Homo sapiens] 40 0.009 gi|24497460 Shaw-related voltage-gated potassium channel protein... 39 0.027 gi|224493919 zinc finger and SCAN domain containing 18 isoform 2... 36 0.13 gi|224493912 zinc finger and SCAN domain containing 18 isoform 3... 36 0.13 gi|222144283 hypothetical protein LOC65998 [Homo sapiens] 36 0.13 gi|226371704 zinc finger and SCAN domain containing 18 isoform 3... 36 0.13 gi|224493905 zinc finger and SCAN domain containing 18 isoform 1... 36 0.13 gi|45827729 scribble isoform b [Homo sapiens] 36 0.13 gi|45827731 scribble isoform a [Homo sapiens] 36 0.13 gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 36 0.13 gi|21313638 leucine-rich repeat LGI family, member 2 [Homo sapiens] 36 0.13 gi|169211815 PREDICTED: keratin associated protein 4.6 [Homo sap... 36 0.18 gi|190684671 mitogen-activated protein kinase binding protein 1 ... 35 0.23 gi|190684677 mitogen-activated protein kinase binding protein 1 ... 35 0.23 gi|221139761 zinc finger protein 853 [Homo sapiens] 35 0.30 gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens] 35 0.30 gi|31982899 seven in absentia homolog 2 [Homo sapiens] 35 0.30 gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 35 0.30 >gi|23238208 interleukin 17A receptor precursor [Homo sapiens] Length = 866 Score = 1793 bits (4643), Expect = 0.0 Identities = 866/866 (100%), Positives = 866/866 (100%) Query: 1 MGAARSPPSAVPGPLLGLLLLLLGVLAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDD 60 MGAARSPPSAVPGPLLGLLLLLLGVLAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDD Sbjct: 1 MGAARSPPSAVPGPLLGLLLLLLGVLAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDD 60 Query: 61 SWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLN 120 SWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLN Sbjct: 61 SWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLN 120 Query: 121 TNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNF 180 TNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNF Sbjct: 121 TNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNF 180 Query: 181 LVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHM 240 LVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHM Sbjct: 181 LVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHM 240 Query: 241 ENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSAT 300 ENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSAT Sbjct: 241 ENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSAT 300 Query: 301 VSCPEMPDTPEPIPDYMPLWVYWFITGISILLVGSVILLIVCMTWRLAGPGSEKYSDDTK 360 VSCPEMPDTPEPIPDYMPLWVYWFITGISILLVGSVILLIVCMTWRLAGPGSEKYSDDTK Sbjct: 301 VSCPEMPDTPEPIPDYMPLWVYWFITGISILLVGSVILLIVCMTWRLAGPGSEKYSDDTK 360 Query: 361 YTDGLPAADLIPPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAI 420 YTDGLPAADLIPPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAI Sbjct: 361 YTDGLPAADLIPPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAI 420 Query: 421 SEAGVMTWVGRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFT 480 SEAGVMTWVGRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFT Sbjct: 421 SEAGVMTWVGRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFT 480 Query: 481 AAMNMILPDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLE 540 AAMNMILPDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLE Sbjct: 481 AAMNMILPDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLE 540 Query: 541 MFQPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQDAPS 600 MFQPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQDAPS Sbjct: 541 MFQPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQDAPS 600 Query: 601 LDEEVFEEPLLPPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQP 660 LDEEVFEEPLLPPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQP Sbjct: 601 LDEEVFEEPLLPPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQP 660 Query: 661 APQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPGAGRNSVLFLP 720 APQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPGAGRNSVLFLP Sbjct: 661 APQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPGAGRNSVLFLP 720 Query: 721 VDPEDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFEQSLSCQAQGGCSRPAMVLTDPHT 780 VDPEDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFEQSLSCQAQGGCSRPAMVLTDPHT Sbjct: 721 VDPEDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFEQSLSCQAQGGCSRPAMVLTDPHT 780 Query: 781 PYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLESLRSLQ 840 PYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLESLRSLQ Sbjct: 781 PYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLESLRSLQ 840 Query: 841 RQLLFRQLQKNSGWDTMGSESEGPSA 866 RQLLFRQLQKNSGWDTMGSESEGPSA Sbjct: 841 RQLLFRQLQKNSGWDTMGSESEGPSA 866 >gi|27477074 interleukin 17B receptor precursor [Homo sapiens] Length = 502 Score = 149 bits (375), Expect = 1e-35 Identities = 124/496 (25%), Positives = 209/496 (42%), Gaps = 47/496 (9%) Query: 39 RALVCSQPGLNCTVKNSTCLDDSWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEW 98 R+ V +P + C + T W+ +L P +DL+++ GD + ++ W Sbjct: 13 RSAVPREPTVQCG--SETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATGDYSILMNVSW 70 Query: 99 TLQTDASILYLEGAELSVL-QLNTNERLCVRFEFLSKLRHHHR----RWRFTFSHFVVDP 153 L+ DASI L+ ++ V + N CVR + + R +W F++ F V+ Sbjct: 71 VLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWTFSYIGFPVEL 130 Query: 154 DQEYEVTVHHLPKPIPDGDPNHQSKNFLVPDCEHARMKVTTPCMSSGSLWDPNITVETLE 213 + Y + H++P + D S NF P C MK C+ +GSLWDPNIT Sbjct: 131 NTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLWDPNITACKKN 190 Query: 214 AHQLRVSFTLWNESTHYQILLTSFPHMENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNL 273 + V+FT Y L+ HS + P ++ + S V + Sbjct: 191 EETVEVNFTTTPLGNRYMALI-------QHSTIIGFSQVFEPHQKKQTRASVVIPVTGDS 243 Query: 274 KGCCRHQVQIQPFFSSCLNDCLRHSATVSCPEMPDTPEPIPDYMPLWVYWF-ITGISILL 332 +G VQ+ P+F +C +DC+RH TV P P+ + W + +S+L+ Sbjct: 244 EGA---TVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLV 300 Query: 333 VGSVILLIVCMTWRLAGPGSEKYSDDTKYTDGLPAADLIPPPLKPRKVWIIYSADHPLYV 392 V++ + + WR +S T L+P P KV ++Y ++ + Sbjct: 301 ATWVLVAGIYLMWRHERIKKTSFSTTT----------LLP----PIKVLVVYPSE-ICFH 345 Query: 393 DVVLKFAQFLLTACGTEVALDLLEEQAISEAGVMTWVGRQKQEMVESNSKIIVLCSRGTR 452 + F +FL C +EV L+ +++ I+E G + W+ QK ++ K++ L S Sbjct: 346 HTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQK----KAADKVVFLLSNDVN 401 Query: 453 AKWQALLGR--GAPVRLRCDHGKPVGDLFTAAMNMILPDFKRPACFGTYVVCYFSEVSCD 510 + G+ G+P + DLF A N+ D + YVV YF E+ Sbjct: 402 SVCDGTCGKSEGSP-------SENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTK 454 Query: 511 GDVPDLFGAAPRYPLM 526 D + P+Y LM Sbjct: 455 DDY-NALSVCPKYHLM 469 >gi|166063983 interleukin 17 receptor D [Homo sapiens] Length = 739 Score = 101 bits (251), Expect = 3e-21 Identities = 125/442 (28%), Positives = 186/442 (42%), Gaps = 76/442 (17%) Query: 353 EKYSDDTKYTDGLPAADLIPPPLKPRKVWIIYSA-DHPLYVDVVLKFAQFLLTACGTEVA 411 E+ S+ + YT LP L P P KV++ YS+ D +++VV FA FL CG EVA Sbjct: 335 EESSESSTYTAALPRERLRPRP----KVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVA 390 Query: 412 LDLLEEQAISEAGVMTWVGRQKQEMVESNSKIIVLCSRGTR----AKWQALLGRGAPVRL 467 LDL E+ ++ G WV + + + IIV+CS+G + K G G Sbjct: 391 LDLWEDFSLCREGQREWV----IQKIHESQFIIVVCSKGMKYFVDKKNYKHKGGG----- 441 Query: 468 RCDHGKPVGDLFTAAMNMILPDFKR-----PACFGTYVVCYFSEVSCDGDVPDLFGAAPR 522 G G+LF A++ I ++ A ++ YF + SC+GDVP + + + Sbjct: 442 ---RGSGKGELFLVAVSAIAEKLRQAKQSSSAALSKFIAVYF-DYSCEGDVPGILDLSTK 497 Query: 523 YPLMDRFEEV--YFRIQDLEMFQPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVR 580 Y LMD ++ + +D + +PG+ R G S NY RS GR L A+ + Sbjct: 498 YRLMDNLPQLCSHLHSRDHGLQEPGQHTRQG--SRRNYFRSKSGRSLYVAICNMHQFIDE 555 Query: 581 CPDWFECENLYSADDQDAPSLDEEVFEEPLLPP-GTGIVKRAPLVRE-PGSQACLAIDPL 638 PDWFE + + P L + EP+L +G+V + + P S CL ++ Sbjct: 556 EPDWFEKQFV----PFHPPPLR---YREPVLEKFDSGLVLNDVMCKPGPESDFCLKVEAA 608 Query: 639 VGEEGGAAVAKLEPHLQPRGQPAPQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAG 698 V G A ++ E ++ G L E P DG+A L Sbjct: 609 VLGATGPADSQHE--------------------SQHGGLDQDGEARPALDGSAALQPLLH 648 Query: 699 EGEACPLLGSPG-AGRNSVLF---LPVDPEDSPL--GSSTPMASPDLLPEDVR------E 746 +A GSP R+S ++ +P PL G ST L E V E Sbjct: 649 TVKA----GSPSDMPRDSGIYDSSVPSSELSLPLMEGLSTDQTETSSLTESVSSSSGLGE 704 Query: 747 HLEGLMLSLFEQSLSCQAQGGC 768 + S S SC+A GC Sbjct: 705 EEPPALPSKLLSSGSCKADLGC 726 >gi|24430197 interleukin 17 receptor C isoform 1 precursor [Homo sapiens] Length = 791 Score = 55.8 bits (133), Expect = 2e-07 Identities = 51/198 (25%), Positives = 83/198 (41%), Gaps = 22/198 (11%) Query: 378 RKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAGVMTWVGRQKQEMV 437 R ++YSAD + +V A L VA+DL + +S G + W Q+++ + Sbjct: 584 RAALLLYSADDSGFERLVGALAS-ALCQLPLRVAVDLWSRRELSAQGPVAWFHAQRRQTL 642 Query: 438 ESNSKIIVLCSRGTRA---KW--QALLGRGAPVRLRCDHGKPVGDLFTAAMNMILPDFKR 492 + +++L S G A +W + G GA HG D F A+++ +LPDF + Sbjct: 643 QEGGVVVLLFSPGAVALCSEWLQDGVSGPGA-------HGPH--DAFRASLSCVLPDFLQ 693 Query: 493 PACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLEMFQPGRMHRVGE 552 G+YV F + VP LF P + L + + +Q + GR+ E Sbjct: 694 GRAPGSYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRAPRSGRLQERAE 753 Query: 553 LSG-------DNYLRSPG 563 D+Y PG Sbjct: 754 QVSRALQPALDSYFHPPG 771 >gi|90669934 interleukin 17 receptor C isoform 3 precursor [Homo sapiens] Length = 705 Score = 55.8 bits (133), Expect = 2e-07 Identities = 51/198 (25%), Positives = 83/198 (41%), Gaps = 22/198 (11%) Query: 378 RKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAGVMTWVGRQKQEMV 437 R ++YSAD + +V A L VA+DL + +S G + W Q+++ + Sbjct: 498 RAALLLYSADDSGFERLVGALAS-ALCQLPLRVAVDLWSRRELSAQGPVAWFHAQRRQTL 556 Query: 438 ESNSKIIVLCSRGTRA---KW--QALLGRGAPVRLRCDHGKPVGDLFTAAMNMILPDFKR 492 + +++L S G A +W + G GA HG D F A+++ +LPDF + Sbjct: 557 QEGGVVVLLFSPGAVALCSEWLQDGVSGPGA-------HGPH--DAFRASLSCVLPDFLQ 607 Query: 493 PACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLEMFQPGRMHRVGE 552 G+YV F + VP LF P + L + + +Q + GR+ E Sbjct: 608 GRAPGSYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRAPRSGRLQERAE 667 Query: 553 LSG-------DNYLRSPG 563 D+Y PG Sbjct: 668 QVSRALQPALDSYFHPPG 685 >gi|24430195 interleukin 17 receptor C isoform 2 precursor [Homo sapiens] Length = 720 Score = 55.8 bits (133), Expect = 2e-07 Identities = 51/198 (25%), Positives = 83/198 (41%), Gaps = 22/198 (11%) Query: 378 RKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAGVMTWVGRQKQEMV 437 R ++YSAD + +V A L VA+DL + +S G + W Q+++ + Sbjct: 513 RAALLLYSADDSGFERLVGALAS-ALCQLPLRVAVDLWSRRELSAQGPVAWFHAQRRQTL 571 Query: 438 ESNSKIIVLCSRGTRA---KW--QALLGRGAPVRLRCDHGKPVGDLFTAAMNMILPDFKR 492 + +++L S G A +W + G GA HG D F A+++ +LPDF + Sbjct: 572 QEGGVVVLLFSPGAVALCSEWLQDGVSGPGA-------HGPH--DAFRASLSCVLPDFLQ 622 Query: 493 PACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLEMFQPGRMHRVGE 552 G+YV F + VP LF P + L + + +Q + GR+ E Sbjct: 623 GRAPGSYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRAPRSGRLQERAE 682 Query: 553 LSG-------DNYLRSPG 563 D+Y PG Sbjct: 683 QVSRALQPALDSYFHPPG 700 >gi|61742808 hypothetical protein LOC283638 isoform 2 [Homo sapiens] Length = 1484 Score = 46.2 bits (108), Expect = 1e-04 Identities = 68/280 (24%), Positives = 101/280 (36%), Gaps = 46/280 (16%) Query: 619 KRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQP--------RGQPAPQPLHTLVL 670 +R+P R PG + +G++ G AV +P P QP+P P V Sbjct: 713 RRSP--RAPGEPTPASF--FIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSP-PARDGVY 767 Query: 671 AAEEGALVAAVEPG--PLADGAAVRLALAGEGEACPLLGSPGAGRNSVLFLPVDPEDSPL 728 + G +V + PG P DG A P G P G+ P PL Sbjct: 768 VSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGK------PPHISSHPL 821 Query: 729 G---SSTPMASPD-------LLPEDVREHLEGLMLSLFEQSLSCQAQGGCS-RPAMVLTD 777 ++T A D L+ ++ L L L S+ + +GG + RP Sbjct: 822 LQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALS 881 Query: 778 PHTPYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPAL----------- 826 + + S++S + S ++PQP EM QDPG AL Sbjct: 882 GDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQ 941 Query: 827 --PLSPEDLESLRSLQRQLLFRQLQKNSGWDTMGSESEGP 864 PL P D+ ++R + R + D SE GP Sbjct: 942 HHPLGPTDMGRGEPVRRSAIRRGHRPRGSLD-WPSEERGP 980 >gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo sapiens] Length = 1554 Score = 46.2 bits (108), Expect = 1e-04 Identities = 68/280 (24%), Positives = 101/280 (36%), Gaps = 46/280 (16%) Query: 619 KRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQP--------RGQPAPQPLHTLVL 670 +R+P R PG + +G++ G AV +P P QP+P P V Sbjct: 783 RRSP--RAPGEPTPASF--FIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSP-PARDGVY 837 Query: 671 AAEEGALVAAVEPG--PLADGAAVRLALAGEGEACPLLGSPGAGRNSVLFLPVDPEDSPL 728 + G +V + PG P DG A P G P G+ P PL Sbjct: 838 VSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGK------PPHISSHPL 891 Query: 729 G---SSTPMASPD-------LLPEDVREHLEGLMLSLFEQSLSCQAQGGCS-RPAMVLTD 777 ++T A D L+ ++ L L L S+ + +GG + RP Sbjct: 892 LQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALS 951 Query: 778 PHTPYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPAL----------- 826 + + S++S + S ++PQP EM QDPG AL Sbjct: 952 GDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQ 1011 Query: 827 --PLSPEDLESLRSLQRQLLFRQLQKNSGWDTMGSESEGP 864 PL P D+ ++R + R + D SE GP Sbjct: 1012 HHPLGPTDMGRGEPVRRSAIRRGHRPRGSLD-WPSEERGP 1050 >gi|5032179 tripartite motif-containing 28 protein [Homo sapiens] Length = 835 Score = 41.2 bits (95), Expect = 0.004 Identities = 35/109 (32%), Positives = 46/109 (42%), Gaps = 9/109 (8%) Query: 638 LVGEEGGAAVAKLEPHLQPRGQPAPQPLHTLVLAAEEGALVAAVEPGPLADG---AAVRL 694 +V E G AA A +P P G P PL + + EE A P +G V + Sbjct: 520 IVIERGAAAAATGQPGTAPAGTPGAPPLAGMAIVKEEETEAAIGAPPTATEGPETKPVLM 579 Query: 695 ALA-GEGEACPLLGSPGAGRNSVLFLPVDPEDSPLGSSTPMASPDLLPE 742 ALA G G P L SP +S L + +P G+S P P L + Sbjct: 580 ALAEGPGAEGPRLASPSGSTSSGLEVV-----APEGTSAPGGGPGTLDD 623 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 40.8 bits (94), Expect = 0.005 Identities = 66/251 (26%), Positives = 91/251 (36%), Gaps = 34/251 (13%) Query: 588 ENLYSADDQDAPSLDEEVFEEPLLPPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAV 647 E L+ + + P L V EEP L P +P EP CL+ P EE + Sbjct: 802 EELHLSPQTEEPHLSP-VPEEPCLSPQPEESHLSPQSEEP----CLSPRP---EESHLSP 853 Query: 648 AKLEPHLQPRGQPAPQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLG 707 +P L PR + P EE A E PL GE PLLG Sbjct: 854 ELEKPPLSPRPEKPP----------EEPGQCPAPEELPL-------FPPPGEPSLSPLLG 896 Query: 708 SPGAGRNSVLFLPVDPEDSPLG-SSTPMASPDLLPED-VREHLEGLMLSLFEQSLSCQAQ 765 P L PE+ PL S P SP L+P D + L ++ + +LS + Sbjct: 897 EPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGE 956 Query: 766 GGCSRPAMVLTDPHTPYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPA 825 A +DP +P ++ S + + P+P + PG P Sbjct: 957 LEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMI-------LPPSPGSPV 1009 Query: 826 LPLSPEDLESL 836 P SP +E L Sbjct: 1010 GPASPILMEPL 1020 Score = 32.3 bits (72), Expect = 1.9 Identities = 68/309 (22%), Positives = 109/309 (35%), Gaps = 50/309 (16%) Query: 598 APSLDEEVFEEPLLPPGTGIVKRAPLVR--EPG-SQACLAIDPLVGEEGGAAVAKLEPHL 654 +P L E EP PP + + + PL EP S + DPL A P L Sbjct: 892 SPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL 951 Query: 655 QPRGQPAPQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLL------GS 708 P G+ P + E L A + P++ + E P + GS Sbjct: 952 SPLGE-LEYPFGAKGDSDPESPLAAPILETPISPPPEANCT---DPEPVPPMILPPSPGS 1007 Query: 709 PGAGRNSVLFLPVDPEDSPL--------GSSTPMASPDLLPEDVREHLE--GLMLSLFEQ 758 P + +L P+ P+ SPL S SP LP V L G ++ + ++ Sbjct: 1008 PVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDE 1067 Query: 759 SLSCQAQGGCSRPAMVLTDPHTPYEEEQRQS-VQSDQGYISRSSPQPP------------ 805 + + + +++P P E S + S G +S +P P Sbjct: 1068 AELHEME------TEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGED 1121 Query: 806 ----EGLTEMEEEEEEEQDPGKPALPLSPE----DLESLRSLQRQLLFRQLQKNSGWDTM 857 +G+ + E Q PG A L D E L + ++ + ++ +G + Sbjct: 1122 TAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSP 1181 Query: 858 GSESEGPSA 866 E E P A Sbjct: 1182 CEEQEEPRA 1190 Score = 30.4 bits (67), Expect = 7.4 Identities = 62/230 (26%), Positives = 78/230 (33%), Gaps = 43/230 (18%) Query: 612 PPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQPAPQPLHTLVLA 671 P G + P +EPG C A PL G A +LEP L+ PL+ Sbjct: 396 PKGGHVTSMQP--KEPGPLQCEA-KPL-----GKAGVQLEPQLEA-------PLN----- 435 Query: 672 AEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPGAGRNSVL--FLPVDPEDSPLG 729 EE L+ E PL+ E P P A R S LP P L Sbjct: 436 -EEMPLLPPPEESPLSPPP----------EESPTSPPPEASRLSPPPEELPASPLPEALH 484 Query: 730 SSTPMASPDLLPEDVREHL----EGLMLSLFEQSLSCQAQGGCSRPAMVLTDPHTPYEEE 785 S P+ L P L E S E+S + S P+ L P +P E Sbjct: 485 LSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEE--SPPSPALETPLSPPPEA 542 Query: 786 QRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLES 835 S ++ +S PPE L E P P+SP ES Sbjct: 543 SPLSPPFEESPLS----PPPEELPTSPPPEASRLSPPPEESPMSPPPEES 588 >gi|24430210 interleukin 17 receptor E isoform 1 [Homo sapiens] Length = 667 Score = 40.0 bits (92), Expect = 0.009 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 30/159 (18%) Query: 372 PPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACG--TEVALDLLEEQAISEAGVMTWV 429 P P +P V ++++AD +V A+ L A G +V +DL E + ++ G + W+ Sbjct: 484 PGPARP--VLLLHAADSEAQRRLVGALAELLRAALGGGRDVIVDLWEGRHVARVGPLPWL 541 Query: 430 GRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVG--DLFTAAMNMIL 487 + + +++L S GA +R PV D A + +L Sbjct: 542 WAARTRVAREQGTVLLLWS-------------GADLR-------PVSGPDPRAAPLLALL 581 Query: 488 PDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLM 526 RP ++ YFS + GD+P A PRY L+ Sbjct: 582 HAAPRPLL----LLAYFSRLCAKGDIPPPLRALPRYRLL 616 >gi|24430206 interleukin 17 receptor E isoform 2 [Homo sapiens] Length = 551 Score = 40.0 bits (92), Expect = 0.009 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 30/159 (18%) Query: 372 PPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACG--TEVALDLLEEQAISEAGVMTWV 429 P P +P V ++++AD +V A+ L A G +V +DL E + ++ G + W+ Sbjct: 368 PGPARP--VLLLHAADSEAQRRLVGALAELLRAALGGGRDVIVDLWEGRHVARVGPLPWL 425 Query: 430 GRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVG--DLFTAAMNMIL 487 + + +++L S GA +R PV D A + +L Sbjct: 426 WAARTRVAREQGTVLLLWS-------------GADLR-------PVSGPDPRAAPLLALL 465 Query: 488 PDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLM 526 RP ++ YFS + GD+P A PRY L+ Sbjct: 466 HAAPRPLL----LLAYFSRLCAKGDIPPPLRALPRYRLL 500 >gi|24430204 interleukin 17 receptor E isoform 1 [Homo sapiens] Length = 667 Score = 40.0 bits (92), Expect = 0.009 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 30/159 (18%) Query: 372 PPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACG--TEVALDLLEEQAISEAGVMTWV 429 P P +P V ++++AD +V A+ L A G +V +DL E + ++ G + W+ Sbjct: 484 PGPARP--VLLLHAADSEAQRRLVGALAELLRAALGGGRDVIVDLWEGRHVARVGPLPWL 541 Query: 430 GRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVG--DLFTAAMNMIL 487 + + +++L S GA +R PV D A + +L Sbjct: 542 WAARTRVAREQGTVLLLWS-------------GADLR-------PVSGPDPRAAPLLALL 581 Query: 488 PDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLM 526 RP ++ YFS + GD+P A PRY L+ Sbjct: 582 HAAPRPLL----LLAYFSRLCAKGDIPPPLRALPRYRLL 616 >gi|24497460 Shaw-related voltage-gated potassium channel protein 3 [Homo sapiens] Length = 757 Score = 38.5 bits (88), Expect = 0.027 Identities = 44/155 (28%), Positives = 56/155 (36%), Gaps = 33/155 (21%) Query: 609 PLLPPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQPAPQPLHTL 668 P+ PP G+ P + L L G GG + L P P G+P P Sbjct: 599 PITPPSMGVTVAGAYPAGPHTHPGL----LRGGAGGLGIMGLPPLPAP-GEPCP------ 647 Query: 669 VLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPGA----------------G 712 LA EE + +P P D AA LA E CP + P Sbjct: 648 -LAQEEVIEINRADPRPNGDPAAAALA----HEDCPAIDQPAMSPEDKSPITPGSRGRYS 702 Query: 713 RNSVLFLPVDPEDSPLGS-STPMASPDLLPEDVRE 746 R+ FL D SP GS +P L P+D R+ Sbjct: 703 RDRACFLLTDYAPSPDGSIRKATGAPPLPPQDWRK 737 >gi|224493919 zinc finger and SCAN domain containing 18 isoform 2 [Homo sapiens] Length = 374 Score = 36.2 bits (82), Expect = 0.13 Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 7/63 (11%) Query: 804 PPEGLTEMEEEEEEEQDPGKPALPLSPEDLE--SLRSLQRQLLFRQLQKNSGWDTMGSES 861 PP G TE EEE+ PGK P P+D E S QRQ + +Q + G +G++ Sbjct: 181 PPSGTTE-----EEEEQPGKAPDPQDPQDAESDSATGSQRQSVIQQPAPDRGTAKLGTKR 235 Query: 862 EGP 864 P Sbjct: 236 PHP 238 >gi|224493912 zinc finger and SCAN domain containing 18 isoform 3 [Homo sapiens] Length = 510 Score = 36.2 bits (82), Expect = 0.13 Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 7/63 (11%) Query: 804 PPEGLTEMEEEEEEEQDPGKPALPLSPEDLE--SLRSLQRQLLFRQLQKNSGWDTMGSES 861 PP G TE EEE+ PGK P P+D E S QRQ + +Q + G +G++ Sbjct: 317 PPSGTTE-----EEEEQPGKAPDPQDPQDAESDSATGSQRQSVIQQPAPDRGTAKLGTKR 371 Query: 862 EGP 864 P Sbjct: 372 PHP 374 >gi|222144283 hypothetical protein LOC65998 [Homo sapiens] Length = 678 Score = 36.2 bits (82), Expect = 0.13 Identities = 19/48 (39%), Positives = 27/48 (56%) Query: 783 EEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSP 830 EEE+ + + + G + S P E E EE+EE+ Q+PG ALP P Sbjct: 517 EEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGLALPPPP 564 >gi|226371704 zinc finger and SCAN domain containing 18 isoform 3 [Homo sapiens] Length = 510 Score = 36.2 bits (82), Expect = 0.13 Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 7/63 (11%) Query: 804 PPEGLTEMEEEEEEEQDPGKPALPLSPEDLE--SLRSLQRQLLFRQLQKNSGWDTMGSES 861 PP G TE EEE+ PGK P P+D E S QRQ + +Q + G +G++ Sbjct: 317 PPSGTTE-----EEEEQPGKAPDPQDPQDAESDSATGSQRQSVIQQPAPDRGTAKLGTKR 371 Query: 862 EGP 864 P Sbjct: 372 PHP 374 >gi|224493905 zinc finger and SCAN domain containing 18 isoform 1 [Homo sapiens] Length = 566 Score = 36.2 bits (82), Expect = 0.13 Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 7/63 (11%) Query: 804 PPEGLTEMEEEEEEEQDPGKPALPLSPEDLE--SLRSLQRQLLFRQLQKNSGWDTMGSES 861 PP G TE EEE+ PGK P P+D E S QRQ + +Q + G +G++ Sbjct: 373 PPSGTTE-----EEEEQPGKAPDPQDPQDAESDSATGSQRQSVIQQPAPDRGTAKLGTKR 427 Query: 862 EGP 864 P Sbjct: 428 PHP 430 >gi|45827729 scribble isoform b [Homo sapiens] Length = 1630 Score = 36.2 bits (82), Expect = 0.13 Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 17/117 (14%) Query: 723 PEDSPLGSSTP--MASPDLLPEDVREHLEGLMLSLFEQSLSC-QAQGGCSRPAMVLTDPH 779 PED+P TP ASP+ L R+ FE + QA+G R ++V D Sbjct: 1333 PEDAPAQPPTPGPAASPEQLSFRERQ-------KYFELEVRVPQAEGPPKRVSLVGADDL 1385 Query: 780 TPYEEEQRQSVQSDQGYISRSSPQPP-------EGLTEMEEEEEEEQDPGKPALPLS 829 +EE+ + +Q + + R + + +G T EEE+E+EQ P P S Sbjct: 1386 RKMQEEEARKLQQKRAQMLREAAEAGAEARLALDGETLGEEEQEDEQPPWASPSPTS 1442 >gi|45827731 scribble isoform a [Homo sapiens] Length = 1655 Score = 36.2 bits (82), Expect = 0.13 Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 17/117 (14%) Query: 723 PEDSPLGSSTP--MASPDLLPEDVREHLEGLMLSLFEQSLSC-QAQGGCSRPAMVLTDPH 779 PED+P TP ASP+ L R+ FE + QA+G R ++V D Sbjct: 1333 PEDAPAQPPTPGPAASPEQLSFRERQ-------KYFELEVRVPQAEGPPKRVSLVGADDL 1385 Query: 780 TPYEEEQRQSVQSDQGYISRSSPQPP-------EGLTEMEEEEEEEQDPGKPALPLS 829 +EE+ + +Q + + R + + +G T EEE+E+EQ P P S Sbjct: 1386 RKMQEEEARKLQQKRAQMLREAAEAGAEARLALDGETLGEEEQEDEQPPWASPSPTS 1442 >gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] Length = 1489 Score = 36.2 bits (82), Expect = 0.13 Identities = 54/183 (29%), Positives = 72/183 (39%), Gaps = 37/183 (20%) Query: 652 PHLQPRG-QPAPQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEAC-PLLGSP 709 P QPR +PAP V A EG EPG A AL+G+G+ P P Sbjct: 1183 PEAQPRRLEPAPPRARPEV--APEG------EPGAPDSRAGGDTALSGDGDPPKPERKGP 1234 Query: 710 GAGRNSVLFLPVDPEDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFEQSLSCQAQGGCS 769 R LFL + P P G+S E ++ L L L+L +L+ G Sbjct: 1235 EMPR---LFLDLGP---PQGNS----------EQIKARLSRLSLALPPLTLTPFPGPGPR 1278 Query: 770 RPAMVLTDPHTPYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQ--DPGKPALP 827 RP P+E + + G P +G E E+EEE+E+ PG A P Sbjct: 1279 RP---------PWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGP 1329 Query: 828 LSP 830 P Sbjct: 1330 RGP 1332 >gi|21313638 leucine-rich repeat LGI family, member 2 [Homo sapiens] Length = 545 Score = 36.2 bits (82), Expect = 0.13 Identities = 35/124 (28%), Positives = 52/124 (41%), Gaps = 26/124 (20%) Query: 16 LGLLLLLLGV--LAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNLTPSSP 73 LGLLLLLLG L P A +R L CS CT ++ C+ SW+ PR + P Sbjct: 11 LGLLLLLLGAACLIPRSAQVRRLARCPATCS-----CTKESIICVGSSWV-PR-IVP--- 60 Query: 74 KDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLNTNERLCVRFEFLS 133 GD+ ++ + T ++ L +L LN+N +R + + Sbjct: 61 --------------GDISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFA 106 Query: 134 KLRH 137 L H Sbjct: 107 GLFH 110 >gi|169211815 PREDICTED: keratin associated protein 4.6 [Homo sapiens] Length = 288 Score = 35.8 bits (81), Expect = 0.18 Identities = 33/133 (24%), Positives = 51/133 (38%), Gaps = 5/133 (3%) Query: 612 PPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQPAPQPLHTLVLA 671 PP + P +P + + A PL A+ A + P G P +L A Sbjct: 156 PPAAALAAVYPAAADPSAASLCAASPLAAVPAAASPAAVAPAAVCPGAAGPSAA-SLCAA 214 Query: 672 AEEGALVAAVEP---GPLA-DGAAVRLALAGEGEACPLLGSPGAGRNSVLFLPVDPEDSP 727 ++ A+ AA P PLA + AA A A AC + + PV +P Sbjct: 215 SQPAAVPAAASPAAAAPLAVNPAAAARAAAAPAAACVQSVAESPATPLAIAQPVSFPPAP 274 Query: 728 LGSSTPMASPDLL 740 + + P + +LL Sbjct: 275 VPCAVPPLAAELL 287 >gi|190684671 mitogen-activated protein kinase binding protein 1 isoform a [Homo sapiens] Length = 1508 Score = 35.4 bits (80), Expect = 0.23 Identities = 57/243 (23%), Positives = 85/243 (34%), Gaps = 34/243 (13%) Query: 621 APLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQPAPQ-------PLHTLVLAAE 673 AP +++P SQ LAI P + G + Q P PQ P +L+ E Sbjct: 873 APSLQDP-SQDSLAIIPSGPRKHGQEALETSLTSQNEKPPRPQASQPCSYPHIIRLLSQE 931 Query: 674 EGALVAAVEPGPLADGAAV----------RLALAGEGEACPLLGSPGAGRNSVLFLPVDP 723 EG +EP P+ DG + A LG G S D Sbjct: 932 EGVFAQDLEPAPIEDGIVYPEPSDNPTMDTSEFQVQAPARGTLGRVYPGSRSSEKHSPDS 991 Query: 724 EDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFEQSLSCQAQGGCSRPAMVLTDPHTPYE 783 S SS+ ++SP+ ED E E L + L A+G E Sbjct: 992 ACSVDYSSSCLSSPEHPTED-SESTEPLSVDGISSDLEEPAEG--------------DEE 1036 Query: 784 EEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLESLRSLQRQL 843 EE+ + G + SPQ P+ +++ E P P+ + RS+ + Sbjct: 1037 EEEEEGGMGPYG-LQEGSPQTPDQEQFLKQHFETLASGAAPGAPVQVPERSESRSISSRF 1095 Query: 844 LFR 846 L + Sbjct: 1096 LLQ 1098 >gi|190684677 mitogen-activated protein kinase binding protein 1 isoform b [Homo sapiens] Length = 1514 Score = 35.4 bits (80), Expect = 0.23 Identities = 57/243 (23%), Positives = 85/243 (34%), Gaps = 34/243 (13%) Query: 621 APLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQPAPQ-------PLHTLVLAAE 673 AP +++P SQ LAI P + G + Q P PQ P +L+ E Sbjct: 879 APSLQDP-SQDSLAIIPSGPRKHGQEALETSLTSQNEKPPRPQASQPCSYPHIIRLLSQE 937 Query: 674 EGALVAAVEPGPLADGAAV----------RLALAGEGEACPLLGSPGAGRNSVLFLPVDP 723 EG +EP P+ DG + A LG G S D Sbjct: 938 EGVFAQDLEPAPIEDGIVYPEPSDNPTMDTSEFQVQAPARGTLGRVYPGSRSSEKHSPDS 997 Query: 724 EDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFEQSLSCQAQGGCSRPAMVLTDPHTPYE 783 S SS+ ++SP+ ED E E L + L A+G E Sbjct: 998 ACSVDYSSSCLSSPEHPTED-SESTEPLSVDGISSDLEEPAEG--------------DEE 1042 Query: 784 EEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLESLRSLQRQL 843 EE+ + G + SPQ P+ +++ E P P+ + RS+ + Sbjct: 1043 EEEEEGGMGPYG-LQEGSPQTPDQEQFLKQHFETLASGAAPGAPVQVPERSESRSISSRF 1101 Query: 844 LFR 846 L + Sbjct: 1102 LLQ 1104 >gi|221139761 zinc finger protein 853 [Homo sapiens] Length = 659 Score = 35.0 bits (79), Expect = 0.30 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 4/71 (5%) Query: 783 EEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDP----GKPALPLSPEDLESLRS 838 +++Q+Q +Q Q + + QPP E EEE E E P + L ++LE + Sbjct: 288 QQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQE 347 Query: 839 LQRQLLFRQLQ 849 L+RQ RQLQ Sbjct: 348 LERQQEQRQLQ 358 >gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens] Length = 931 Score = 35.0 bits (79), Expect = 0.30 Identities = 60/233 (25%), Positives = 82/233 (35%), Gaps = 45/233 (19%) Query: 635 IDPLVGEEGGAAVAKLEPHLQPRGQPAPQPLHTLVLAAEEGALVAAVEPGPL-ADGAAVR 693 IDP G +V + LQP +P P P L+L + +L+ V P L D Sbjct: 609 IDPCAVAPGPPSVVVKQEALQPEPEPVPAP--QLLLGPQGPSLIKGVAPPTLITDSTGTH 666 Query: 694 LALAGEGEACPLLGSPGAGRNSVLFLPVDPEDSPLGSSTPMASPDLLPEDVREHLEGLML 753 L L + SPG S P P P GS P S + E + L G Sbjct: 667 LVLTVTNKNA---DSPGLSSGS----PQQPSSQP-GSPAPAPSAQMDLEHPLQPLFGTPT 718 Query: 754 SL-------FEQSLSCQAQ----GGCSRPAMVLTD---------------PHTPYEEEQR 787 SL +E+++S Q + G S+ L D P P +E+ Sbjct: 719 SLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPS 778 Query: 788 QSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPED-LESLRSL 839 ++ SP E + PG P+LP ED LES L Sbjct: 779 PKTVCGSPLAAQPSP-------SAELPQAAPPPPGSPSLPGRLEDFLESSTGL 824 >gi|31982899 seven in absentia homolog 2 [Homo sapiens] Length = 324 Score = 35.0 bits (79), Expect = 0.30 Identities = 32/111 (28%), Positives = 44/111 (39%), Gaps = 25/111 (22%) Query: 659 QPAPQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGE-----ACPLLGSPGAGR 713 QP PQP HT P P A AA ++ AG G A ++ PG G Sbjct: 18 QPPPQPQHT---------------PSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGG 62 Query: 714 NSVLFLPVDPEDSPLGS--STPMASPDLLPEDVREHLEGLMLSLFEQSLSC 762 + PV P+ L S P+ +LP ++ L+ + Q LSC Sbjct: 63 GAG---PVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSC 110 >gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e [Homo sapiens] Length = 1451 Score = 35.0 bits (79), Expect = 0.30 Identities = 52/231 (22%), Positives = 84/231 (36%), Gaps = 27/231 (11%) Query: 644 GAAVAKLEPHLQPRGQPAPQPLHTLVLAAEEGALV----AAVEPGPLADGAAVRLA--LA 697 G VA L PR P TLV EE V AA +PG ++ G A + + Sbjct: 145 GKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTS 204 Query: 698 GEGEACPLLGSPGAGRNSVLFLPVDPEDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFE 757 + + G P V V ++SP + P P V + Sbjct: 205 SSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP------APGKVGD----------- 247 Query: 758 QSLSCQAQGGCSRPAMVLTDPHTPYEEEQRQSVQSDQGYI-SRSSPQPPEGLTEMEEEEE 816 ++ Q +GG PA P E + S ++ +RS + E + ++ Sbjct: 248 --VTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASA 305 Query: 817 EEQ-DPGKPALPLSPEDLESLRSLQRQLLFRQLQKNSGWDTMGSESEGPSA 866 + PGK A P P ++ S + + ++S ++ SE E P+A Sbjct: 306 PAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAA 356 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.137 0.430 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 41,419,733 Number of Sequences: 37866 Number of extensions: 2273581 Number of successful extensions: 11210 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 27 Number of HSP's successfully gapped in prelim test: 186 Number of HSP's that attempted gapping in prelim test: 10512 Number of HSP's gapped (non-prelim): 798 length of query: 866 length of database: 18,247,518 effective HSP length: 111 effective length of query: 755 effective length of database: 14,044,392 effective search space: 10603515960 effective search space used: 10603515960 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.