Guide to the Human Genome
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Search of human proteins with 23238208

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23238208 interleukin 17A receptor precursor [Homo sapiens]
         (866 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23238208 interleukin 17A receptor precursor [Homo sapiens]        1793   0.0  
gi|27477074 interleukin 17B receptor precursor [Homo sapiens]         149   1e-35
gi|166063983 interleukin 17 receptor D [Homo sapiens]                 101   3e-21
gi|24430197 interleukin 17 receptor C isoform 1 precursor [Homo ...    56   2e-07
gi|90669934 interleukin 17 receptor C isoform 3 precursor [Homo ...    56   2e-07
gi|24430195 interleukin 17 receptor C isoform 2 precursor [Homo ...    56   2e-07
gi|61742808 hypothetical protein LOC283638 isoform 2 [Homo sapiens]    46   1e-04
gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo sapi...    46   1e-04
gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]       41   0.004
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    41   0.005
gi|24430210 interleukin 17 receptor E isoform 1 [Homo sapiens]         40   0.009
gi|24430206 interleukin 17 receptor E isoform 2 [Homo sapiens]         40   0.009
gi|24430204 interleukin 17 receptor E isoform 1 [Homo sapiens]         40   0.009
gi|24497460 Shaw-related voltage-gated potassium channel protein...    39   0.027
gi|224493919 zinc finger and SCAN domain containing 18 isoform 2...    36   0.13 
gi|224493912 zinc finger and SCAN domain containing 18 isoform 3...    36   0.13 
gi|222144283 hypothetical protein LOC65998 [Homo sapiens]              36   0.13 
gi|226371704 zinc finger and SCAN domain containing 18 isoform 3...    36   0.13 
gi|224493905 zinc finger and SCAN domain containing 18 isoform 1...    36   0.13 
gi|45827729 scribble isoform b [Homo sapiens]                          36   0.13 
gi|45827731 scribble isoform a [Homo sapiens]                          36   0.13 
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    36   0.13 
gi|21313638 leucine-rich repeat LGI family, member 2 [Homo sapiens]    36   0.13 
gi|169211815 PREDICTED: keratin associated protein 4.6 [Homo sap...    36   0.18 
gi|190684671 mitogen-activated protein kinase binding protein 1 ...    35   0.23 
gi|190684677 mitogen-activated protein kinase binding protein 1 ...    35   0.23 
gi|221139761 zinc finger protein 853 [Homo sapiens]                    35   0.30 
gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]         35   0.30 
gi|31982899 seven in absentia homolog 2 [Homo sapiens]                 35   0.30 
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    35   0.30 

>gi|23238208 interleukin 17A receptor precursor [Homo sapiens]
          Length = 866

 Score = 1793 bits (4643), Expect = 0.0
 Identities = 866/866 (100%), Positives = 866/866 (100%)

Query: 1   MGAARSPPSAVPGPLLGLLLLLLGVLAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDD 60
           MGAARSPPSAVPGPLLGLLLLLLGVLAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDD
Sbjct: 1   MGAARSPPSAVPGPLLGLLLLLLGVLAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDD 60

Query: 61  SWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLN 120
           SWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLN
Sbjct: 61  SWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLN 120

Query: 121 TNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNF 180
           TNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNF
Sbjct: 121 TNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNF 180

Query: 181 LVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHM 240
           LVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHM
Sbjct: 181 LVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHM 240

Query: 241 ENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSAT 300
           ENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSAT
Sbjct: 241 ENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSAT 300

Query: 301 VSCPEMPDTPEPIPDYMPLWVYWFITGISILLVGSVILLIVCMTWRLAGPGSEKYSDDTK 360
           VSCPEMPDTPEPIPDYMPLWVYWFITGISILLVGSVILLIVCMTWRLAGPGSEKYSDDTK
Sbjct: 301 VSCPEMPDTPEPIPDYMPLWVYWFITGISILLVGSVILLIVCMTWRLAGPGSEKYSDDTK 360

Query: 361 YTDGLPAADLIPPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAI 420
           YTDGLPAADLIPPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAI
Sbjct: 361 YTDGLPAADLIPPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAI 420

Query: 421 SEAGVMTWVGRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFT 480
           SEAGVMTWVGRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFT
Sbjct: 421 SEAGVMTWVGRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFT 480

Query: 481 AAMNMILPDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLE 540
           AAMNMILPDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLE
Sbjct: 481 AAMNMILPDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLE 540

Query: 541 MFQPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQDAPS 600
           MFQPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQDAPS
Sbjct: 541 MFQPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQDAPS 600

Query: 601 LDEEVFEEPLLPPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQP 660
           LDEEVFEEPLLPPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQP
Sbjct: 601 LDEEVFEEPLLPPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQP 660

Query: 661 APQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPGAGRNSVLFLP 720
           APQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPGAGRNSVLFLP
Sbjct: 661 APQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPGAGRNSVLFLP 720

Query: 721 VDPEDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFEQSLSCQAQGGCSRPAMVLTDPHT 780
           VDPEDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFEQSLSCQAQGGCSRPAMVLTDPHT
Sbjct: 721 VDPEDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFEQSLSCQAQGGCSRPAMVLTDPHT 780

Query: 781 PYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLESLRSLQ 840
           PYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLESLRSLQ
Sbjct: 781 PYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLESLRSLQ 840

Query: 841 RQLLFRQLQKNSGWDTMGSESEGPSA 866
           RQLLFRQLQKNSGWDTMGSESEGPSA
Sbjct: 841 RQLLFRQLQKNSGWDTMGSESEGPSA 866


>gi|27477074 interleukin 17B receptor precursor [Homo sapiens]
          Length = 502

 Score =  149 bits (375), Expect = 1e-35
 Identities = 124/496 (25%), Positives = 209/496 (42%), Gaps = 47/496 (9%)

Query: 39  RALVCSQPGLNCTVKNSTCLDDSWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEW 98
           R+ V  +P + C   + T     W+   +L P   +DL+++        GD   + ++ W
Sbjct: 13  RSAVPREPTVQCG--SETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATGDYSILMNVSW 70

Query: 99  TLQTDASILYLEGAELSVL-QLNTNERLCVRFEFLSKLRHHHR----RWRFTFSHFVVDP 153
            L+ DASI  L+  ++ V  + N     CVR  +    +   R    +W F++  F V+ 
Sbjct: 71  VLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWTFSYIGFPVEL 130

Query: 154 DQEYEVTVHHLPKPIPDGDPNHQSKNFLVPDCEHARMKVTTPCMSSGSLWDPNITVETLE 213
           +  Y +  H++P    + D    S NF  P C    MK    C+ +GSLWDPNIT     
Sbjct: 131 NTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLWDPNITACKKN 190

Query: 214 AHQLRVSFTLWNESTHYQILLTSFPHMENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNL 273
              + V+FT       Y  L+        HS       +  P  ++  + S V     + 
Sbjct: 191 EETVEVNFTTTPLGNRYMALI-------QHSTIIGFSQVFEPHQKKQTRASVVIPVTGDS 243

Query: 274 KGCCRHQVQIQPFFSSCLNDCLRHSATVSCPEMPDTPEPIPDYMPLWVYWF-ITGISILL 332
           +G     VQ+ P+F +C +DC+RH  TV        P P+ +       W  +  +S+L+
Sbjct: 244 EGA---TVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLV 300

Query: 333 VGSVILLIVCMTWRLAGPGSEKYSDDTKYTDGLPAADLIPPPLKPRKVWIIYSADHPLYV 392
              V++  + + WR        +S  T          L+P    P KV ++Y ++   + 
Sbjct: 301 ATWVLVAGIYLMWRHERIKKTSFSTTT----------LLP----PIKVLVVYPSE-ICFH 345

Query: 393 DVVLKFAQFLLTACGTEVALDLLEEQAISEAGVMTWVGRQKQEMVESNSKIIVLCSRGTR 452
             +  F +FL   C +EV L+  +++ I+E G + W+  QK    ++  K++ L S    
Sbjct: 346 HTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQK----KAADKVVFLLSNDVN 401

Query: 453 AKWQALLGR--GAPVRLRCDHGKPVGDLFTAAMNMILPDFKRPACFGTYVVCYFSEVSCD 510
           +      G+  G+P        +   DLF  A N+   D +       YVV YF E+   
Sbjct: 402 SVCDGTCGKSEGSP-------SENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTK 454

Query: 511 GDVPDLFGAAPRYPLM 526
            D  +     P+Y LM
Sbjct: 455 DDY-NALSVCPKYHLM 469


>gi|166063983 interleukin 17 receptor D [Homo sapiens]
          Length = 739

 Score =  101 bits (251), Expect = 3e-21
 Identities = 125/442 (28%), Positives = 186/442 (42%), Gaps = 76/442 (17%)

Query: 353 EKYSDDTKYTDGLPAADLIPPPLKPRKVWIIYSA-DHPLYVDVVLKFAQFLLTACGTEVA 411
           E+ S+ + YT  LP   L P P    KV++ YS+ D   +++VV  FA FL   CG EVA
Sbjct: 335 EESSESSTYTAALPRERLRPRP----KVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVA 390

Query: 412 LDLLEEQAISEAGVMTWVGRQKQEMVESNSKIIVLCSRGTR----AKWQALLGRGAPVRL 467
           LDL E+ ++   G   WV     + +  +  IIV+CS+G +     K     G G     
Sbjct: 391 LDLWEDFSLCREGQREWV----IQKIHESQFIIVVCSKGMKYFVDKKNYKHKGGG----- 441

Query: 468 RCDHGKPVGDLFTAAMNMILPDFKR-----PACFGTYVVCYFSEVSCDGDVPDLFGAAPR 522
               G   G+LF  A++ I    ++      A    ++  YF + SC+GDVP +   + +
Sbjct: 442 ---RGSGKGELFLVAVSAIAEKLRQAKQSSSAALSKFIAVYF-DYSCEGDVPGILDLSTK 497

Query: 523 YPLMDRFEEV--YFRIQDLEMFQPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVR 580
           Y LMD   ++  +   +D  + +PG+  R G  S  NY RS  GR L  A+     +   
Sbjct: 498 YRLMDNLPQLCSHLHSRDHGLQEPGQHTRQG--SRRNYFRSKSGRSLYVAICNMHQFIDE 555

Query: 581 CPDWFECENLYSADDQDAPSLDEEVFEEPLLPP-GTGIVKRAPLVRE-PGSQACLAIDPL 638
            PDWFE + +        P L    + EP+L    +G+V    + +  P S  CL ++  
Sbjct: 556 EPDWFEKQFV----PFHPPPLR---YREPVLEKFDSGLVLNDVMCKPGPESDFCLKVEAA 608

Query: 639 VGEEGGAAVAKLEPHLQPRGQPAPQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAG 698
           V    G A ++ E                    ++ G L    E  P  DG+A    L  
Sbjct: 609 VLGATGPADSQHE--------------------SQHGGLDQDGEARPALDGSAALQPLLH 648

Query: 699 EGEACPLLGSPG-AGRNSVLF---LPVDPEDSPL--GSSTPMASPDLLPEDVR------E 746
             +A    GSP    R+S ++   +P      PL  G ST       L E V       E
Sbjct: 649 TVKA----GSPSDMPRDSGIYDSSVPSSELSLPLMEGLSTDQTETSSLTESVSSSSGLGE 704

Query: 747 HLEGLMLSLFEQSLSCQAQGGC 768
                + S    S SC+A  GC
Sbjct: 705 EEPPALPSKLLSSGSCKADLGC 726


>gi|24430197 interleukin 17 receptor C isoform 1 precursor [Homo
           sapiens]
          Length = 791

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 51/198 (25%), Positives = 83/198 (41%), Gaps = 22/198 (11%)

Query: 378 RKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAGVMTWVGRQKQEMV 437
           R   ++YSAD   +  +V   A   L      VA+DL   + +S  G + W   Q+++ +
Sbjct: 584 RAALLLYSADDSGFERLVGALAS-ALCQLPLRVAVDLWSRRELSAQGPVAWFHAQRRQTL 642

Query: 438 ESNSKIIVLCSRGTRA---KW--QALLGRGAPVRLRCDHGKPVGDLFTAAMNMILPDFKR 492
           +    +++L S G  A   +W    + G GA       HG    D F A+++ +LPDF +
Sbjct: 643 QEGGVVVLLFSPGAVALCSEWLQDGVSGPGA-------HGPH--DAFRASLSCVLPDFLQ 693

Query: 493 PACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLEMFQPGRMHRVGE 552
               G+YV   F  +     VP LF   P + L  +  +    +Q     + GR+    E
Sbjct: 694 GRAPGSYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRAPRSGRLQERAE 753

Query: 553 LSG-------DNYLRSPG 563
                     D+Y   PG
Sbjct: 754 QVSRALQPALDSYFHPPG 771


>gi|90669934 interleukin 17 receptor C isoform 3 precursor [Homo
           sapiens]
          Length = 705

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 51/198 (25%), Positives = 83/198 (41%), Gaps = 22/198 (11%)

Query: 378 RKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAGVMTWVGRQKQEMV 437
           R   ++YSAD   +  +V   A   L      VA+DL   + +S  G + W   Q+++ +
Sbjct: 498 RAALLLYSADDSGFERLVGALAS-ALCQLPLRVAVDLWSRRELSAQGPVAWFHAQRRQTL 556

Query: 438 ESNSKIIVLCSRGTRA---KW--QALLGRGAPVRLRCDHGKPVGDLFTAAMNMILPDFKR 492
           +    +++L S G  A   +W    + G GA       HG    D F A+++ +LPDF +
Sbjct: 557 QEGGVVVLLFSPGAVALCSEWLQDGVSGPGA-------HGPH--DAFRASLSCVLPDFLQ 607

Query: 493 PACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLEMFQPGRMHRVGE 552
               G+YV   F  +     VP LF   P + L  +  +    +Q     + GR+    E
Sbjct: 608 GRAPGSYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRAPRSGRLQERAE 667

Query: 553 LSG-------DNYLRSPG 563
                     D+Y   PG
Sbjct: 668 QVSRALQPALDSYFHPPG 685


>gi|24430195 interleukin 17 receptor C isoform 2 precursor [Homo
           sapiens]
          Length = 720

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 51/198 (25%), Positives = 83/198 (41%), Gaps = 22/198 (11%)

Query: 378 RKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAGVMTWVGRQKQEMV 437
           R   ++YSAD   +  +V   A   L      VA+DL   + +S  G + W   Q+++ +
Sbjct: 513 RAALLLYSADDSGFERLVGALAS-ALCQLPLRVAVDLWSRRELSAQGPVAWFHAQRRQTL 571

Query: 438 ESNSKIIVLCSRGTRA---KW--QALLGRGAPVRLRCDHGKPVGDLFTAAMNMILPDFKR 492
           +    +++L S G  A   +W    + G GA       HG    D F A+++ +LPDF +
Sbjct: 572 QEGGVVVLLFSPGAVALCSEWLQDGVSGPGA-------HGPH--DAFRASLSCVLPDFLQ 622

Query: 493 PACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLEMFQPGRMHRVGE 552
               G+YV   F  +     VP LF   P + L  +  +    +Q     + GR+    E
Sbjct: 623 GRAPGSYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRAPRSGRLQERAE 682

Query: 553 LSG-------DNYLRSPG 563
                     D+Y   PG
Sbjct: 683 QVSRALQPALDSYFHPPG 700


>gi|61742808 hypothetical protein LOC283638 isoform 2 [Homo sapiens]
          Length = 1484

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 68/280 (24%), Positives = 101/280 (36%), Gaps = 46/280 (16%)

Query: 619 KRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQP--------RGQPAPQPLHTLVL 670
           +R+P  R PG     +    +G++ G AV   +P   P          QP+P P    V 
Sbjct: 713 RRSP--RAPGEPTPASF--FIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSP-PARDGVY 767

Query: 671 AAEEGALVAAVEPG--PLADGAAVRLALAGEGEACPLLGSPGAGRNSVLFLPVDPEDSPL 728
            +  G +V  + PG  P  DG A            P  G P  G+      P      PL
Sbjct: 768 VSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGK------PPHISSHPL 821

Query: 729 G---SSTPMASPD-------LLPEDVREHLEGLMLSLFEQSLSCQAQGGCS-RPAMVLTD 777
               ++T  A  D       L+ ++    L  L   L   S+  + +GG + RP      
Sbjct: 822 LQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALS 881

Query: 778 PHTPYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPAL----------- 826
             +  +     S++S +   S ++PQP     EM       QDPG  AL           
Sbjct: 882 GDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQ 941

Query: 827 --PLSPEDLESLRSLQRQLLFRQLQKNSGWDTMGSESEGP 864
             PL P D+     ++R  + R  +     D   SE  GP
Sbjct: 942 HHPLGPTDMGRGEPVRRSAIRRGHRPRGSLD-WPSEERGP 980


>gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo sapiens]
          Length = 1554

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 68/280 (24%), Positives = 101/280 (36%), Gaps = 46/280 (16%)

Query: 619  KRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQP--------RGQPAPQPLHTLVL 670
            +R+P  R PG     +    +G++ G AV   +P   P          QP+P P    V 
Sbjct: 783  RRSP--RAPGEPTPASF--FIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSP-PARDGVY 837

Query: 671  AAEEGALVAAVEPG--PLADGAAVRLALAGEGEACPLLGSPGAGRNSVLFLPVDPEDSPL 728
             +  G +V  + PG  P  DG A            P  G P  G+      P      PL
Sbjct: 838  VSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGK------PPHISSHPL 891

Query: 729  G---SSTPMASPD-------LLPEDVREHLEGLMLSLFEQSLSCQAQGGCS-RPAMVLTD 777
                ++T  A  D       L+ ++    L  L   L   S+  + +GG + RP      
Sbjct: 892  LQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALS 951

Query: 778  PHTPYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPAL----------- 826
              +  +     S++S +   S ++PQP     EM       QDPG  AL           
Sbjct: 952  GDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQ 1011

Query: 827  --PLSPEDLESLRSLQRQLLFRQLQKNSGWDTMGSESEGP 864
              PL P D+     ++R  + R  +     D   SE  GP
Sbjct: 1012 HHPLGPTDMGRGEPVRRSAIRRGHRPRGSLD-WPSEERGP 1050


>gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]
          Length = 835

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 35/109 (32%), Positives = 46/109 (42%), Gaps = 9/109 (8%)

Query: 638 LVGEEGGAAVAKLEPHLQPRGQPAPQPLHTLVLAAEEGALVAAVEPGPLADG---AAVRL 694
           +V E G AA A  +P   P G P   PL  + +  EE    A   P    +G     V +
Sbjct: 520 IVIERGAAAAATGQPGTAPAGTPGAPPLAGMAIVKEEETEAAIGAPPTATEGPETKPVLM 579

Query: 695 ALA-GEGEACPLLGSPGAGRNSVLFLPVDPEDSPLGSSTPMASPDLLPE 742
           ALA G G   P L SP    +S L +      +P G+S P   P  L +
Sbjct: 580 ALAEGPGAEGPRLASPSGSTSSGLEVV-----APEGTSAPGGGPGTLDD 623


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 66/251 (26%), Positives = 91/251 (36%), Gaps = 34/251 (13%)

Query: 588  ENLYSADDQDAPSLDEEVFEEPLLPPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAV 647
            E L+ +   + P L   V EEP L P       +P   EP    CL+  P   EE   + 
Sbjct: 802  EELHLSPQTEEPHLSP-VPEEPCLSPQPEESHLSPQSEEP----CLSPRP---EESHLSP 853

Query: 648  AKLEPHLQPRGQPAPQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLG 707
               +P L PR +  P          EE     A E  PL           GE    PLLG
Sbjct: 854  ELEKPPLSPRPEKPP----------EEPGQCPAPEELPL-------FPPPGEPSLSPLLG 896

Query: 708  SPGAGRNSVLFLPVDPEDSPLG-SSTPMASPDLLPED-VREHLEGLMLSLFEQSLSCQAQ 765
             P         L   PE+ PL  S  P  SP L+P D +   L  ++ +    +LS   +
Sbjct: 897  EPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGE 956

Query: 766  GGCSRPAMVLTDPHTPYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPA 825
                  A   +DP +P      ++  S     + + P+P   +            PG P 
Sbjct: 957  LEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMI-------LPPSPGSPV 1009

Query: 826  LPLSPEDLESL 836
             P SP  +E L
Sbjct: 1010 GPASPILMEPL 1020



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 68/309 (22%), Positives = 109/309 (35%), Gaps = 50/309 (16%)

Query: 598  APSLDEEVFEEPLLPPGTGIVKRAPLVR--EPG-SQACLAIDPLVGEEGGAAVAKLEPHL 654
            +P L E    EP  PP + + +  PL    EP  S   +  DPL         A   P L
Sbjct: 892  SPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL 951

Query: 655  QPRGQPAPQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLL------GS 708
             P G+    P      +  E  L A +   P++           + E  P +      GS
Sbjct: 952  SPLGE-LEYPFGAKGDSDPESPLAAPILETPISPPPEANCT---DPEPVPPMILPPSPGS 1007

Query: 709  PGAGRNSVLFLPVDPEDSPL--------GSSTPMASPDLLPEDVREHLE--GLMLSLFEQ 758
            P    + +L  P+ P+ SPL         S     SP  LP  V   L   G ++ + ++
Sbjct: 1008 PVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDE 1067

Query: 759  SLSCQAQGGCSRPAMVLTDPHTPYEEEQRQS-VQSDQGYISRSSPQPP------------ 805
            +   + +         +++P  P  E    S + S  G +S  +P P             
Sbjct: 1068 AELHEME------TEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGED 1121

Query: 806  ----EGLTEMEEEEEEEQDPGKPALPLSPE----DLESLRSLQRQLLFRQLQKNSGWDTM 857
                +G+     + E  Q PG  A  L       D E L  +    ++ + ++ +G  + 
Sbjct: 1122 TAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSP 1181

Query: 858  GSESEGPSA 866
              E E P A
Sbjct: 1182 CEEQEEPRA 1190



 Score = 30.4 bits (67), Expect = 7.4
 Identities = 62/230 (26%), Positives = 78/230 (33%), Gaps = 43/230 (18%)

Query: 612 PPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQPAPQPLHTLVLA 671
           P G  +    P  +EPG   C A  PL     G A  +LEP L+        PL+     
Sbjct: 396 PKGGHVTSMQP--KEPGPLQCEA-KPL-----GKAGVQLEPQLEA-------PLN----- 435

Query: 672 AEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPGAGRNSVL--FLPVDPEDSPLG 729
            EE  L+   E  PL+             E  P    P A R S     LP  P    L 
Sbjct: 436 -EEMPLLPPPEESPLSPPP----------EESPTSPPPEASRLSPPPEELPASPLPEALH 484

Query: 730 SSTPMASPDLLPEDVREHL----EGLMLSLFEQSLSCQAQGGCSRPAMVLTDPHTPYEEE 785
            S P+    L P      L    E    S  E+S     +   S P+  L  P +P  E 
Sbjct: 485 LSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEE--SPPSPALETPLSPPPEA 542

Query: 786 QRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLES 835
              S   ++  +S     PPE L      E     P     P+SP   ES
Sbjct: 543 SPLSPPFEESPLS----PPPEELPTSPPPEASRLSPPPEESPMSPPPEES 588


>gi|24430210 interleukin 17 receptor E isoform 1 [Homo sapiens]
          Length = 667

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 30/159 (18%)

Query: 372 PPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACG--TEVALDLLEEQAISEAGVMTWV 429
           P P +P  V ++++AD      +V   A+ L  A G   +V +DL E + ++  G + W+
Sbjct: 484 PGPARP--VLLLHAADSEAQRRLVGALAELLRAALGGGRDVIVDLWEGRHVARVGPLPWL 541

Query: 430 GRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVG--DLFTAAMNMIL 487
              +  +      +++L S             GA +R       PV   D   A +  +L
Sbjct: 542 WAARTRVAREQGTVLLLWS-------------GADLR-------PVSGPDPRAAPLLALL 581

Query: 488 PDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLM 526
               RP      ++ YFS +   GD+P    A PRY L+
Sbjct: 582 HAAPRPLL----LLAYFSRLCAKGDIPPPLRALPRYRLL 616


>gi|24430206 interleukin 17 receptor E isoform 2 [Homo sapiens]
          Length = 551

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 30/159 (18%)

Query: 372 PPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACG--TEVALDLLEEQAISEAGVMTWV 429
           P P +P  V ++++AD      +V   A+ L  A G   +V +DL E + ++  G + W+
Sbjct: 368 PGPARP--VLLLHAADSEAQRRLVGALAELLRAALGGGRDVIVDLWEGRHVARVGPLPWL 425

Query: 430 GRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVG--DLFTAAMNMIL 487
              +  +      +++L S             GA +R       PV   D   A +  +L
Sbjct: 426 WAARTRVAREQGTVLLLWS-------------GADLR-------PVSGPDPRAAPLLALL 465

Query: 488 PDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLM 526
               RP      ++ YFS +   GD+P    A PRY L+
Sbjct: 466 HAAPRPLL----LLAYFSRLCAKGDIPPPLRALPRYRLL 500


>gi|24430204 interleukin 17 receptor E isoform 1 [Homo sapiens]
          Length = 667

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 30/159 (18%)

Query: 372 PPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACG--TEVALDLLEEQAISEAGVMTWV 429
           P P +P  V ++++AD      +V   A+ L  A G   +V +DL E + ++  G + W+
Sbjct: 484 PGPARP--VLLLHAADSEAQRRLVGALAELLRAALGGGRDVIVDLWEGRHVARVGPLPWL 541

Query: 430 GRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVG--DLFTAAMNMIL 487
              +  +      +++L S             GA +R       PV   D   A +  +L
Sbjct: 542 WAARTRVAREQGTVLLLWS-------------GADLR-------PVSGPDPRAAPLLALL 581

Query: 488 PDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLM 526
               RP      ++ YFS +   GD+P    A PRY L+
Sbjct: 582 HAAPRPLL----LLAYFSRLCAKGDIPPPLRALPRYRLL 616


>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
           [Homo sapiens]
          Length = 757

 Score = 38.5 bits (88), Expect = 0.027
 Identities = 44/155 (28%), Positives = 56/155 (36%), Gaps = 33/155 (21%)

Query: 609 PLLPPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQPAPQPLHTL 668
           P+ PP  G+         P +   L    L G  GG  +  L P   P G+P P      
Sbjct: 599 PITPPSMGVTVAGAYPAGPHTHPGL----LRGGAGGLGIMGLPPLPAP-GEPCP------ 647

Query: 669 VLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPGA----------------G 712
            LA EE   +   +P P  D AA  LA     E CP +  P                   
Sbjct: 648 -LAQEEVIEINRADPRPNGDPAAAALA----HEDCPAIDQPAMSPEDKSPITPGSRGRYS 702

Query: 713 RNSVLFLPVDPEDSPLGS-STPMASPDLLPEDVRE 746
           R+   FL  D   SP GS      +P L P+D R+
Sbjct: 703 RDRACFLLTDYAPSPDGSIRKATGAPPLPPQDWRK 737


>gi|224493919 zinc finger and SCAN domain containing 18 isoform 2
           [Homo sapiens]
          Length = 374

 Score = 36.2 bits (82), Expect = 0.13
 Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 7/63 (11%)

Query: 804 PPEGLTEMEEEEEEEQDPGKPALPLSPEDLE--SLRSLQRQLLFRQLQKNSGWDTMGSES 861
           PP G TE     EEE+ PGK   P  P+D E  S    QRQ + +Q   + G   +G++ 
Sbjct: 181 PPSGTTE-----EEEEQPGKAPDPQDPQDAESDSATGSQRQSVIQQPAPDRGTAKLGTKR 235

Query: 862 EGP 864
             P
Sbjct: 236 PHP 238


>gi|224493912 zinc finger and SCAN domain containing 18 isoform 3
           [Homo sapiens]
          Length = 510

 Score = 36.2 bits (82), Expect = 0.13
 Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 7/63 (11%)

Query: 804 PPEGLTEMEEEEEEEQDPGKPALPLSPEDLE--SLRSLQRQLLFRQLQKNSGWDTMGSES 861
           PP G TE     EEE+ PGK   P  P+D E  S    QRQ + +Q   + G   +G++ 
Sbjct: 317 PPSGTTE-----EEEEQPGKAPDPQDPQDAESDSATGSQRQSVIQQPAPDRGTAKLGTKR 371

Query: 862 EGP 864
             P
Sbjct: 372 PHP 374


>gi|222144283 hypothetical protein LOC65998 [Homo sapiens]
          Length = 678

 Score = 36.2 bits (82), Expect = 0.13
 Identities = 19/48 (39%), Positives = 27/48 (56%)

Query: 783 EEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSP 830
           EEE+ +  + + G +  S   P E   E EE+EE+ Q+PG  ALP  P
Sbjct: 517 EEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGLALPPPP 564


>gi|226371704 zinc finger and SCAN domain containing 18 isoform 3
           [Homo sapiens]
          Length = 510

 Score = 36.2 bits (82), Expect = 0.13
 Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 7/63 (11%)

Query: 804 PPEGLTEMEEEEEEEQDPGKPALPLSPEDLE--SLRSLQRQLLFRQLQKNSGWDTMGSES 861
           PP G TE     EEE+ PGK   P  P+D E  S    QRQ + +Q   + G   +G++ 
Sbjct: 317 PPSGTTE-----EEEEQPGKAPDPQDPQDAESDSATGSQRQSVIQQPAPDRGTAKLGTKR 371

Query: 862 EGP 864
             P
Sbjct: 372 PHP 374


>gi|224493905 zinc finger and SCAN domain containing 18 isoform 1
           [Homo sapiens]
          Length = 566

 Score = 36.2 bits (82), Expect = 0.13
 Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 7/63 (11%)

Query: 804 PPEGLTEMEEEEEEEQDPGKPALPLSPEDLE--SLRSLQRQLLFRQLQKNSGWDTMGSES 861
           PP G TE     EEE+ PGK   P  P+D E  S    QRQ + +Q   + G   +G++ 
Sbjct: 373 PPSGTTE-----EEEEQPGKAPDPQDPQDAESDSATGSQRQSVIQQPAPDRGTAKLGTKR 427

Query: 862 EGP 864
             P
Sbjct: 428 PHP 430


>gi|45827729 scribble isoform b [Homo sapiens]
          Length = 1630

 Score = 36.2 bits (82), Expect = 0.13
 Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 17/117 (14%)

Query: 723  PEDSPLGSSTP--MASPDLLPEDVREHLEGLMLSLFEQSLSC-QAQGGCSRPAMVLTDPH 779
            PED+P    TP   ASP+ L    R+         FE  +   QA+G   R ++V  D  
Sbjct: 1333 PEDAPAQPPTPGPAASPEQLSFRERQ-------KYFELEVRVPQAEGPPKRVSLVGADDL 1385

Query: 780  TPYEEEQRQSVQSDQGYISRSSPQPP-------EGLTEMEEEEEEEQDPGKPALPLS 829
               +EE+ + +Q  +  + R + +         +G T  EEE+E+EQ P     P S
Sbjct: 1386 RKMQEEEARKLQQKRAQMLREAAEAGAEARLALDGETLGEEEQEDEQPPWASPSPTS 1442


>gi|45827731 scribble isoform a [Homo sapiens]
          Length = 1655

 Score = 36.2 bits (82), Expect = 0.13
 Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 17/117 (14%)

Query: 723  PEDSPLGSSTP--MASPDLLPEDVREHLEGLMLSLFEQSLSC-QAQGGCSRPAMVLTDPH 779
            PED+P    TP   ASP+ L    R+         FE  +   QA+G   R ++V  D  
Sbjct: 1333 PEDAPAQPPTPGPAASPEQLSFRERQ-------KYFELEVRVPQAEGPPKRVSLVGADDL 1385

Query: 780  TPYEEEQRQSVQSDQGYISRSSPQPP-------EGLTEMEEEEEEEQDPGKPALPLS 829
               +EE+ + +Q  +  + R + +         +G T  EEE+E+EQ P     P S
Sbjct: 1386 RKMQEEEARKLQQKRAQMLREAAEAGAEARLALDGETLGEEEQEDEQPPWASPSPTS 1442


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 36.2 bits (82), Expect = 0.13
 Identities = 54/183 (29%), Positives = 72/183 (39%), Gaps = 37/183 (20%)

Query: 652  PHLQPRG-QPAPQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEAC-PLLGSP 709
            P  QPR  +PAP      V  A EG      EPG     A    AL+G+G+   P    P
Sbjct: 1183 PEAQPRRLEPAPPRARPEV--APEG------EPGAPDSRAGGDTALSGDGDPPKPERKGP 1234

Query: 710  GAGRNSVLFLPVDPEDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFEQSLSCQAQGGCS 769
               R   LFL + P   P G+S          E ++  L  L L+L   +L+     G  
Sbjct: 1235 EMPR---LFLDLGP---PQGNS----------EQIKARLSRLSLALPPLTLTPFPGPGPR 1278

Query: 770  RPAMVLTDPHTPYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQ--DPGKPALP 827
            RP         P+E     +   + G      P   +G  E E+EEE+E+   PG  A P
Sbjct: 1279 RP---------PWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGP 1329

Query: 828  LSP 830
              P
Sbjct: 1330 RGP 1332


>gi|21313638 leucine-rich repeat LGI family, member 2 [Homo sapiens]
          Length = 545

 Score = 36.2 bits (82), Expect = 0.13
 Identities = 35/124 (28%), Positives = 52/124 (41%), Gaps = 26/124 (20%)

Query: 16  LGLLLLLLGV--LAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNLTPSSP 73
           LGLLLLLLG   L P  A +R L      CS     CT ++  C+  SW+ PR + P   
Sbjct: 11  LGLLLLLLGAACLIPRSAQVRRLARCPATCS-----CTKESIICVGSSWV-PR-IVP--- 60

Query: 74  KDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLNTNERLCVRFEFLS 133
                         GD+  ++ +  T       ++     L +L LN+N    +R +  +
Sbjct: 61  --------------GDISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFA 106

Query: 134 KLRH 137
            L H
Sbjct: 107 GLFH 110


>gi|169211815 PREDICTED: keratin associated protein 4.6 [Homo
           sapiens]
          Length = 288

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 33/133 (24%), Positives = 51/133 (38%), Gaps = 5/133 (3%)

Query: 612 PPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQPAPQPLHTLVLA 671
           PP   +    P   +P + +  A  PL      A+ A + P     G   P    +L  A
Sbjct: 156 PPAAALAAVYPAAADPSAASLCAASPLAAVPAAASPAAVAPAAVCPGAAGPSAA-SLCAA 214

Query: 672 AEEGALVAAVEP---GPLA-DGAAVRLALAGEGEACPLLGSPGAGRNSVLFLPVDPEDSP 727
           ++  A+ AA  P    PLA + AA   A A    AC    +        +  PV    +P
Sbjct: 215 SQPAAVPAAASPAAAAPLAVNPAAAARAAAAPAAACVQSVAESPATPLAIAQPVSFPPAP 274

Query: 728 LGSSTPMASPDLL 740
           +  + P  + +LL
Sbjct: 275 VPCAVPPLAAELL 287


>gi|190684671 mitogen-activated protein kinase binding protein 1
            isoform a [Homo sapiens]
          Length = 1508

 Score = 35.4 bits (80), Expect = 0.23
 Identities = 57/243 (23%), Positives = 85/243 (34%), Gaps = 34/243 (13%)

Query: 621  APLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQPAPQ-------PLHTLVLAAE 673
            AP +++P SQ  LAI P    + G    +     Q    P PQ       P    +L+ E
Sbjct: 873  APSLQDP-SQDSLAIIPSGPRKHGQEALETSLTSQNEKPPRPQASQPCSYPHIIRLLSQE 931

Query: 674  EGALVAAVEPGPLADGAAV----------RLALAGEGEACPLLGSPGAGRNSVLFLPVDP 723
            EG     +EP P+ DG                   +  A   LG    G  S      D 
Sbjct: 932  EGVFAQDLEPAPIEDGIVYPEPSDNPTMDTSEFQVQAPARGTLGRVYPGSRSSEKHSPDS 991

Query: 724  EDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFEQSLSCQAQGGCSRPAMVLTDPHTPYE 783
              S   SS+ ++SP+   ED  E  E L +      L   A+G                E
Sbjct: 992  ACSVDYSSSCLSSPEHPTED-SESTEPLSVDGISSDLEEPAEG--------------DEE 1036

Query: 784  EEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLESLRSLQRQL 843
            EE+ +      G +   SPQ P+    +++  E       P  P+   +    RS+  + 
Sbjct: 1037 EEEEEGGMGPYG-LQEGSPQTPDQEQFLKQHFETLASGAAPGAPVQVPERSESRSISSRF 1095

Query: 844  LFR 846
            L +
Sbjct: 1096 LLQ 1098


>gi|190684677 mitogen-activated protein kinase binding protein 1
            isoform b [Homo sapiens]
          Length = 1514

 Score = 35.4 bits (80), Expect = 0.23
 Identities = 57/243 (23%), Positives = 85/243 (34%), Gaps = 34/243 (13%)

Query: 621  APLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQPAPQ-------PLHTLVLAAE 673
            AP +++P SQ  LAI P    + G    +     Q    P PQ       P    +L+ E
Sbjct: 879  APSLQDP-SQDSLAIIPSGPRKHGQEALETSLTSQNEKPPRPQASQPCSYPHIIRLLSQE 937

Query: 674  EGALVAAVEPGPLADGAAV----------RLALAGEGEACPLLGSPGAGRNSVLFLPVDP 723
            EG     +EP P+ DG                   +  A   LG    G  S      D 
Sbjct: 938  EGVFAQDLEPAPIEDGIVYPEPSDNPTMDTSEFQVQAPARGTLGRVYPGSRSSEKHSPDS 997

Query: 724  EDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFEQSLSCQAQGGCSRPAMVLTDPHTPYE 783
              S   SS+ ++SP+   ED  E  E L +      L   A+G                E
Sbjct: 998  ACSVDYSSSCLSSPEHPTED-SESTEPLSVDGISSDLEEPAEG--------------DEE 1042

Query: 784  EEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLESLRSLQRQL 843
            EE+ +      G +   SPQ P+    +++  E       P  P+   +    RS+  + 
Sbjct: 1043 EEEEEGGMGPYG-LQEGSPQTPDQEQFLKQHFETLASGAAPGAPVQVPERSESRSISSRF 1101

Query: 844  LFR 846
            L +
Sbjct: 1102 LLQ 1104


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 35.0 bits (79), Expect = 0.30
 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 4/71 (5%)

Query: 783 EEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDP----GKPALPLSPEDLESLRS 838
           +++Q+Q +Q  Q  + +   QPP    E EEE E E  P     +  L    ++LE  + 
Sbjct: 288 QQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQE 347

Query: 839 LQRQLLFRQLQ 849
           L+RQ   RQLQ
Sbjct: 348 LERQQEQRQLQ 358


>gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]
          Length = 931

 Score = 35.0 bits (79), Expect = 0.30
 Identities = 60/233 (25%), Positives = 82/233 (35%), Gaps = 45/233 (19%)

Query: 635 IDPLVGEEGGAAVAKLEPHLQPRGQPAPQPLHTLVLAAEEGALVAAVEPGPL-ADGAAVR 693
           IDP     G  +V   +  LQP  +P P P   L+L  +  +L+  V P  L  D     
Sbjct: 609 IDPCAVAPGPPSVVVKQEALQPEPEPVPAP--QLLLGPQGPSLIKGVAPPTLITDSTGTH 666

Query: 694 LALAGEGEACPLLGSPGAGRNSVLFLPVDPEDSPLGSSTPMASPDLLPEDVREHLEGLML 753
           L L    +      SPG    S    P  P   P GS  P  S  +  E   + L G   
Sbjct: 667 LVLTVTNKNA---DSPGLSSGS----PQQPSSQP-GSPAPAPSAQMDLEHPLQPLFGTPT 718

Query: 754 SL-------FEQSLSCQAQ----GGCSRPAMVLTD---------------PHTPYEEEQR 787
           SL       +E+++S Q +    G  S+    L D               P  P +E+  
Sbjct: 719 SLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPS 778

Query: 788 QSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPED-LESLRSL 839
                     ++ SP         E  +     PG P+LP   ED LES   L
Sbjct: 779 PKTVCGSPLAAQPSP-------SAELPQAAPPPPGSPSLPGRLEDFLESSTGL 824


>gi|31982899 seven in absentia homolog 2 [Homo sapiens]
          Length = 324

 Score = 35.0 bits (79), Expect = 0.30
 Identities = 32/111 (28%), Positives = 44/111 (39%), Gaps = 25/111 (22%)

Query: 659 QPAPQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGE-----ACPLLGSPGAGR 713
           QP PQP HT               P P A  AA  ++ AG G      A  ++  PG G 
Sbjct: 18  QPPPQPQHT---------------PSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGG 62

Query: 714 NSVLFLPVDPEDSPLGS--STPMASPDLLPEDVREHLEGLMLSLFEQSLSC 762
            +    PV P+   L S    P+    +LP  ++     L+ +   Q LSC
Sbjct: 63  GAG---PVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSC 110


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 35.0 bits (79), Expect = 0.30
 Identities = 52/231 (22%), Positives = 84/231 (36%), Gaps = 27/231 (11%)

Query: 644 GAAVAKLEPHLQPRGQPAPQPLHTLVLAAEEGALV----AAVEPGPLADGAAVRLA--LA 697
           G  VA L     PR    P    TLV   EE   V    AA +PG ++ G A   +   +
Sbjct: 145 GKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTS 204

Query: 698 GEGEACPLLGSPGAGRNSVLFLPVDPEDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFE 757
              +   + G P      V    V  ++SP   + P       P  V +           
Sbjct: 205 SSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP------APGKVGD----------- 247

Query: 758 QSLSCQAQGGCSRPAMVLTDPHTPYEEEQRQSVQSDQGYI-SRSSPQPPEGLTEMEEEEE 816
             ++ Q +GG   PA     P    E  +  S   ++    +RS  +  E + ++     
Sbjct: 248 --VTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASA 305

Query: 817 EEQ-DPGKPALPLSPEDLESLRSLQRQLLFRQLQKNSGWDTMGSESEGPSA 866
             +  PGK A P  P    ++ S  +     +  ++S  ++  SE E P+A
Sbjct: 306 PAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAA 356


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,419,733
Number of Sequences: 37866
Number of extensions: 2273581
Number of successful extensions: 11210
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 186
Number of HSP's that attempted gapping in prelim test: 10512
Number of HSP's gapped (non-prelim): 798
length of query: 866
length of database: 18,247,518
effective HSP length: 111
effective length of query: 755
effective length of database: 14,044,392
effective search space: 10603515960
effective search space used: 10603515960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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