Guide to the Human Genome
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Search of human proteins with 23111009

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23111009 myogenic differentiation 1 [Homo sapiens]
         (320 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23111009 myogenic differentiation 1 [Homo sapiens]                 662   0.0  
gi|156104906 myogenic factor 5 [Homo sapiens]                         224   1e-58
gi|4505299 myogenic factor 6 [Homo sapiens]                           130   2e-30
gi|18765727 myogenin [Homo sapiens]                                   128   8e-30
gi|30039710 pancreas specific transcription factor, 1a [Homo sap...    52   5e-07
gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo sapi...    52   5e-07
gi|38455396 neurogenin 1 [Homo sapiens]                                52   9e-07
gi|239751178 PREDICTED: basic helix-loop-helix family, member a9...    51   2e-06
gi|239745666 PREDICTED: basic helix-loop-helix family, member a9...    51   2e-06
gi|239756681 PREDICTED: basic helix-loop-helix family, member a9...    50   2e-06
gi|239752994 PREDICTED: achaete-scute complex homolog 5 (Drosoph...    50   2e-06
gi|239747548 PREDICTED: achaete-scute complex homolog 5 (Drosoph...    50   2e-06
gi|239741422 PREDICTED: achaete-scute complex homolog 5 [Homo sa...    50   2e-06
gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens]         50   2e-06
gi|55743094 achaete-scute complex homolog 1 [Homo sapiens]             50   3e-06
gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]          49   5e-06
gi|4885075 atonal homolog 1 [Homo sapiens]                             47   2e-05
gi|206597481 achaete-scute complex-like 4 [Homo sapiens]               47   3e-05
gi|4507741 twist [Homo sapiens]                                        47   3e-05
gi|17981708 twist homolog 2 [Homo sapiens]                             45   1e-04
gi|21553337 atonal homolog 7 [Homo sapiens]                            45   1e-04
gi|23097242 nephew of atonal 3 [Homo sapiens]                          44   1e-04
gi|48255909 basic helix-loop-helix transcription factor 15 [Homo...    44   1e-04
gi|148922889 scleraxis homolog B [Homo sapiens]                        44   2e-04
gi|186972126 scleraxis homolog A [Homo sapiens]                        44   2e-04
gi|12545384 basic helix-loop-helix transcription factor HAND2 [H...    44   2e-04
gi|31077092 neurogenin 2 [Homo sapiens]                                44   2e-04
gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]          43   4e-04
gi|68989258 neurogenin 3 [Homo sapiens]                                42   6e-04
gi|116517330 factor in the germline alpha [Homo sapiens]               42   7e-04

>gi|23111009 myogenic differentiation 1 [Homo sapiens]
          Length = 320

 Score =  662 bits (1709), Expect = 0.0
 Identities = 320/320 (100%), Positives = 320/320 (100%)

Query: 1   MELLSPPLRDVDLTAPDGSLCSFATTDDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPE 60
           MELLSPPLRDVDLTAPDGSLCSFATTDDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPE
Sbjct: 1   MELLSPPLRDVDLTAPDGSLCSFATTDDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPE 60

Query: 61  EHSHFPAAVHPAPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERR 120
           EHSHFPAAVHPAPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERR
Sbjct: 61  EHSHFPAAVHPAPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERR 120

Query: 121 RLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYA 180
           RLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYA
Sbjct: 121 RLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYA 180

Query: 181 PGPLPPGRGGEHYSGDSDASSPRSNCSDGMMDYSGPPSGARRRNCYEGAYYNEAPSEPRP 240
           PGPLPPGRGGEHYSGDSDASSPRSNCSDGMMDYSGPPSGARRRNCYEGAYYNEAPSEPRP
Sbjct: 181 PGPLPPGRGGEHYSGDSDASSPRSNCSDGMMDYSGPPSGARRRNCYEGAYYNEAPSEPRP 240

Query: 241 GKSAAVSSLDCLSSIVERISTESPAAPALLLADVPSESPPRRQEAAAPSEGESSGDPTQS 300
           GKSAAVSSLDCLSSIVERISTESPAAPALLLADVPSESPPRRQEAAAPSEGESSGDPTQS
Sbjct: 241 GKSAAVSSLDCLSSIVERISTESPAAPALLLADVPSESPPRRQEAAAPSEGESSGDPTQS 300

Query: 301 PDAAPQCPAGANPNPIYQVL 320
           PDAAPQCPAGANPNPIYQVL
Sbjct: 301 PDAAPQCPAGANPNPIYQVL 320


>gi|156104906 myogenic factor 5 [Homo sapiens]
          Length = 255

 Score =  224 bits (570), Expect = 1e-58
 Identities = 132/276 (47%), Positives = 169/276 (61%), Gaps = 37/276 (13%)

Query: 21  CSFATTDDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPEEHSHFPAAVHPAP--GARED 78
           C F+ ++ FYD  C  SP+  F ++  PR+   GA              H A   G+ ED
Sbjct: 7   CQFSPSEYFYDGSCIPSPEGEFGDEFVPRVAAFGA--------------HKAELQGSDED 52

Query: 79  EHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSS 138
           EHVRAP+GHHQAG CL+WACKACKRK+T  DRRKAATMRERRRL KVN+AFETLKRCT++
Sbjct: 53  EHVRAPTGHHQAGHCLMWACKACKRKSTTMDRRKAATMRERRRLKKVNQAFETLKRCTTT 112

Query: 139 NPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYAPGPLPPGRGGEHYSGDSD 198
           NPNQRLPKVEILRNAIRYIE LQ LLR+Q          +  PG              S+
Sbjct: 113 NPNQRLPKVEILRNAIRYIESLQELLREQ------VENYYSLPG-----------QSCSE 155

Query: 199 ASSPRSNCSDGMMDYSGPPSGARRRNCYEGAYYNEAPSEPRPGKSAAVSSLDCLSSIVER 258
            +SP SNCSDGM + +  P  +R+ + ++  Y  +  +     K+ ++SSLDCLS+IV+R
Sbjct: 156 PTSPTSNCSDGMPECNS-PVWSRKSSTFDSIYCPDVSNVYATDKN-SLSSLDCLSNIVDR 213

Query: 259 ISTESPAAPALLLADVPSESPPRRQEAAAPSEGESS 294
           I+  S   P L L D+ S SP    ++   + G SS
Sbjct: 214 IT--SSEQPGLPLQDLASLSPVASTDSQPATPGASS 247


>gi|4505299 myogenic factor 6 [Homo sapiens]
          Length = 242

 Score =  130 bits (327), Expect = 2e-30
 Identities = 85/197 (43%), Positives = 104/197 (52%), Gaps = 24/197 (12%)

Query: 78  DEHVRAPSG---HHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKR 134
           +EHV AP G    H  G+CL+WACK CKRK+   DRRKAAT+RERRRL K+NEAFE LKR
Sbjct: 59  EEHVLAPPGLQPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRERRRLKKINEAFEALKR 118

Query: 135 CTSSNPNQRLPKVEILRNAIRYIEGLQALLR--DQDAAPPGAAAAFYAPGPLPPGRGGEH 192
            T +NPNQRLPKVEILR+AI YIE LQ LL   DQ           ++  P      G  
Sbjct: 119 RTVANPNQRLPKVEILRSAISYIERLQDLLHRLDQQEKMQELGVDPFSYRPKQENLEGAD 178

Query: 193 YSGDSDASSPRSNCSDGMMDYSGPPSGARRRNCYEGAYYNEAPSEPRPGKSAAVSSLDCL 252
           +     +  P  +     +  +    GA                      S+A SSL CL
Sbjct: 179 FLRTCSSQWPSVSDHSRGLVITAKEGGASI-------------------DSSASSSLRCL 219

Query: 253 SSIVERISTESPAAPAL 269
           SSIV+ IS+E    P +
Sbjct: 220 SSIVDSISSEERKLPCV 236


>gi|18765727 myogenin [Homo sapiens]
          Length = 224

 Score =  128 bits (321), Expect = 8e-30
 Identities = 80/186 (43%), Positives = 105/186 (56%), Gaps = 20/186 (10%)

Query: 23  FATTDDFYDDPCFDSPDLRFFEDLDPRLMHVGALLKPEEHSHFPAAVHP-APGAREDEHV 81
           + T+  FY +P       RF++  +   +H+    +P  +      + P APG  ED+ +
Sbjct: 4   YETSPYFYQEP-------RFYDGENYLPVHLQGF-EPPGYERTELTLSPEAPGPLEDKGL 55

Query: 82  RAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSNPN 141
             P   H  G+CL WACK CKRK+ + DRR+AAT+RE+RRL KVNEAFE LKR T  NPN
Sbjct: 56  GTPE--HCPGQCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRSTLLNPN 113

Query: 142 QRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYAPGPLPPGRGGEHYSGDSDASS 201
           QRLPKVEILR+AI+YIE LQALL   +                  G GG      S+ SS
Sbjct: 114 QRLPKVEILRSAIQYIERLQALLSSLNQEERDLRYR---------GGGGPQPGVPSECSS 164

Query: 202 PRSNCS 207
             ++CS
Sbjct: 165 HSASCS 170


>gi|30039710 pancreas specific transcription factor, 1a [Homo
           sapiens]
          Length = 328

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 36/91 (39%), Positives = 47/91 (51%), Gaps = 7/91 (7%)

Query: 111 RKAATMRERRRLSKVNEAFETLKRCTSSNP-NQRLPKVEILRNAIRYIEGLQALLRDQDA 169
           R+AA +RERRR+  +N+AFE L+    + P  +RL KV+ LR AI YI  L  L++    
Sbjct: 165 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQADLP 224

Query: 170 APPGAAAAFYAPGPLPPGRGGEHYSGDSDAS 200
              G A     PG      GG    GDS  S
Sbjct: 225 LRGGGAGGCGGPG------GGGRLGGDSPGS 249


>gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo
           sapiens]
          Length = 280

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 45/125 (36%), Positives = 58/125 (46%), Gaps = 21/125 (16%)

Query: 110 RRKAATMRERRRLSKVNEAFETLKRCTSSNP-NQRLPKVEILRNAIRYIEGLQALLRDQD 168
           RR     RER R   VN AF  L++   ++P +++L K E+LR A++YI  L  LLRDQ 
Sbjct: 151 RRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLRDQ- 209

Query: 169 AAPPGAAAAFYAPGPLPPG-----------RGGEHYSGDSDASSPRSNCSDGMMDYSGPP 217
                  AA  A GP PPG            G    SG    ++ RS  +    D  G P
Sbjct: 210 -------AAALAAGPTPPGPRKRPVHRVPDDGARRGSGRRAEAAARSQPAP-PADPDGSP 261

Query: 218 SGARR 222
            GA R
Sbjct: 262 GGAAR 266


>gi|38455396 neurogenin 1 [Homo sapiens]
          Length = 237

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 45/145 (31%), Positives = 62/145 (42%), Gaps = 16/145 (11%)

Query: 73  PGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETL 132
           PGA++DE  R      + GR  + +       +    RR  A  RER R+  +N A + L
Sbjct: 62  PGAQDDEQER----RRRRGRTRVRS--EALLHSLRRSRRVKANDRERNRMHNLNAALDAL 115

Query: 133 KRCTSSNPNQ-RLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAA---------AFYAPG 182
           +    S P+  +L K+E LR A  YI  L   LR  D   PG  A             PG
Sbjct: 116 RSVLPSFPDDTKLTKIETLRFAYNYIWALAETLRLADQGLPGGGARERLLPPQCVPCLPG 175

Query: 183 PLPPGRGGEHYSGDSDASSPRSNCS 207
           P  P    E +   + A+SP S+ S
Sbjct: 176 PPSPASDAESWGSGAAAASPLSDPS 200


>gi|239751178 PREDICTED: basic helix-loop-helix family, member a9
           [Homo sapiens]
          Length = 235

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 57/183 (31%), Positives = 72/183 (39%), Gaps = 11/183 (6%)

Query: 103 RKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSN-PNQRLPKVEILRNAIRYIEGLQ 161
           R   +  RR AA +RER+R+   NEAF  L+R    +   +RL K+  LR AI  I  L 
Sbjct: 59  RPVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALS 118

Query: 162 ALLRDQDAAPPGAAAAFYAPGPLPPGRGGEHYSGDSDAS-SPRSNCSDGMMDYSGP--PS 218
            +LR    AP G        GP   G      +GD+ AS  P +  S    D + P  PS
Sbjct: 119 LVLR-ASPAPRGPCGHLECHGPAARGD-----TGDTGASPPPPAGPSLARPDAARPSVPS 172

Query: 219 GARRRNCYEGAYYNEAPSEPRPGKSAAVSSLDCLSSIVERISTESPAAPALLLADVPSES 278
             R  +C   A     PS    G   A +S           S   P  P   L   P   
Sbjct: 173 APRCASCPPHAPL-ARPSAVAEGPGLAQASGGSWRRCPGASSAGPPPWPRGYLRSAPGMG 231

Query: 279 PPR 281
            PR
Sbjct: 232 HPR 234


>gi|239745666 PREDICTED: basic helix-loop-helix family, member a9
           [Homo sapiens]
          Length = 235

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 57/183 (31%), Positives = 72/183 (39%), Gaps = 11/183 (6%)

Query: 103 RKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSN-PNQRLPKVEILRNAIRYIEGLQ 161
           R   +  RR AA +RER+R+   NEAF  L+R    +   +RL K+  LR AI  I  L 
Sbjct: 59  RPVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALS 118

Query: 162 ALLRDQDAAPPGAAAAFYAPGPLPPGRGGEHYSGDSDAS-SPRSNCSDGMMDYSGP--PS 218
            +LR    AP G        GP   G      +GD+ AS  P +  S    D + P  PS
Sbjct: 119 LVLR-ASPAPRGPCGHLECHGPAARGD-----TGDTGASPPPPAGPSLARPDAARPSVPS 172

Query: 219 GARRRNCYEGAYYNEAPSEPRPGKSAAVSSLDCLSSIVERISTESPAAPALLLADVPSES 278
             R  +C   A     PS    G   A +S           S   P  P   L   P   
Sbjct: 173 APRCASCPPHAPL-ARPSAVAEGPGLAQASGGSWRRCPGASSAGPPPWPRGYLRSAPGMG 231

Query: 279 PPR 281
            PR
Sbjct: 232 HPR 234


>gi|239756681 PREDICTED: basic helix-loop-helix family, member a9
           [Homo sapiens]
          Length = 203

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 37/101 (36%), Positives = 48/101 (47%), Gaps = 7/101 (6%)

Query: 103 RKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSN-PNQRLPKVEILRNAIRYIEGLQ 161
           R   +  RR AA +RER+R+   NEAF  L+R    +   +RL K+  LR AI  I  L 
Sbjct: 59  RPVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALS 118

Query: 162 ALLRDQDAAPPGAAAAFYAPGPLPPGRGGEHYSGDSDASSP 202
            +LR    AP G        GP   G      +GD+ AS P
Sbjct: 119 LVLR-ASPAPRGPCGHLECHGPAARGD-----TGDTGASPP 153


>gi|239752994 PREDICTED: achaete-scute complex homolog 5
           (Drosophila) [Homo sapiens]
          Length = 313

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 35/92 (38%), Positives = 44/92 (47%), Gaps = 4/92 (4%)

Query: 117 RERRRLSKVNEAFETLK-RCTSSNPNQRLPKVEILRNAIRYIEGLQALLR---DQDAAPP 172
           RER+R+  VNE +  L+     +   +RL KVE LR AIRYI+ LQ LL    D    P 
Sbjct: 198 RERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGSTPPA 257

Query: 173 GAAAAFYAPGPLPPGRGGEHYSGDSDASSPRS 204
                   P P PP        GD +A +P S
Sbjct: 258 SRGLPGTGPCPAPPATPRPDRPGDGEARAPSS 289


>gi|239747548 PREDICTED: achaete-scute complex homolog 5
           (Drosophila) [Homo sapiens]
          Length = 313

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 35/92 (38%), Positives = 44/92 (47%), Gaps = 4/92 (4%)

Query: 117 RERRRLSKVNEAFETLK-RCTSSNPNQRLPKVEILRNAIRYIEGLQALLR---DQDAAPP 172
           RER+R+  VNE +  L+     +   +RL KVE LR AIRYI+ LQ LL    D    P 
Sbjct: 198 RERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGSTPPA 257

Query: 173 GAAAAFYAPGPLPPGRGGEHYSGDSDASSPRS 204
                   P P PP        GD +A +P S
Sbjct: 258 SRGLPGTGPCPAPPATPRPDRPGDGEARAPSS 289


>gi|239741422 PREDICTED: achaete-scute complex homolog 5 [Homo
           sapiens]
          Length = 313

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 35/92 (38%), Positives = 44/92 (47%), Gaps = 4/92 (4%)

Query: 117 RERRRLSKVNEAFETLK-RCTSSNPNQRLPKVEILRNAIRYIEGLQALLR---DQDAAPP 172
           RER+R+  VNE +  L+     +   +RL KVE LR AIRYI+ LQ LL    D    P 
Sbjct: 198 RERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGSTPPA 257

Query: 173 GAAAAFYAPGPLPPGRGGEHYSGDSDASSPRS 204
                   P P PP        GD +A +P S
Sbjct: 258 SRGLPGTGPCPAPPATPRPDRPGDGEARAPSS 289


>gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens]
          Length = 193

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 42/129 (32%), Positives = 54/129 (41%), Gaps = 28/129 (21%)

Query: 117 RERRRLSKVNEAFETLKR-CTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDA------ 169
           RER R+  VN  F+ L++       +++L KVE LR+A+ YI  LQ LL + DA      
Sbjct: 58  RERNRVKLVNLGFQALRQHVPHGGASKKLSKVETLRSAVEYIRALQRLLAEHDAVRNALA 117

Query: 170 --------------APPGAAAAFYAP--GPLPPGRGGEHYSGDSDASSPRSNCSDGMMDY 213
                          PPG      +P      PGRG     G S+  SPRS  S      
Sbjct: 118 GGLRPQAVRPSAPRGPPGTTPVAASPSRASSSPGRG-----GSSEPGSPRSAYSSDDSGC 172

Query: 214 SGPPSGARR 222
            G  S A R
Sbjct: 173 EGALSPAER 181


>gi|55743094 achaete-scute complex homolog 1 [Homo sapiens]
          Length = 236

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 37/100 (37%), Positives = 49/100 (49%), Gaps = 9/100 (9%)

Query: 117 RERRRLSKVNEAFETLKRCTSSNP-NQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAA 175
           RER R+  VN  F TL+    +   N+++ KVE LR+A+ YI  LQ LL + DA      
Sbjct: 126 RERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQ 185

Query: 176 AAFYAPGPLPPGRGGEHYSGD--SDASSPRSNCSDGMMDY 213
           A   +P   P      +YS D  S A SP S+ S     Y
Sbjct: 186 AGVLSPTISP------NYSNDLNSMAGSPVSSYSSDEGSY 219


>gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]
          Length = 331

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 40/122 (32%), Positives = 54/122 (44%), Gaps = 11/122 (9%)

Query: 106 TNADRRKAATMRERRRLSKVNEAFETLKRCTSSNP-NQRLPKVEILRNAIRYIEGLQALL 164
           T   RR     RER R   VN AF  L++   ++P +++L K EILR A++YI  L  LL
Sbjct: 184 TKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLL 243

Query: 165 RDQDAAPPGAAAAFYAPGPLPPGRGGEHYSGD--------SDASSPRSNCSDGMMDYSGP 216
            DQ+    G   A     P+    GG    G          D  SP S+C   +   + P
Sbjct: 244 NDQE--EEGTQRAKTGKDPVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASP 301

Query: 217 PS 218
            S
Sbjct: 302 DS 303


>gi|4885075 atonal homolog 1 [Homo sapiens]
          Length = 354

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 16/113 (14%)

Query: 110 RRKAATMRERRRLSKVNEAFETLKRCTSS-NPNQRLPKVEILRNAIRYIEGLQALLR--- 165
           RR AA  RERRR+  +N AF+ L+    S N +++L K E L+ A  YI  L  LL+   
Sbjct: 160 RRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTPS 219

Query: 166 --DQDAAPPGA----------AAAFYAPGPLPPGRGGEHYSGDSDASSPRSNC 206
             +Q   PP +          AA++          G +  SG S   +P  +C
Sbjct: 220 GGEQPPPPPASCKSDHHHLRTAASYEGGAGNATAAGAQQASGGSQRPTPPGSC 272


>gi|206597481 achaete-scute complex-like 4 [Homo sapiens]
          Length = 173

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 37/93 (39%), Positives = 48/93 (51%), Gaps = 7/93 (7%)

Query: 117 RERRRLSKVNEAFETLK-RCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAA 175
           RER+R+  VNE +  L+        ++RL KVE LR AI YI+ LQ LL  Q     GAA
Sbjct: 81  RERQRVRCVNEGYARLRDHLPRELADKRLSKVETLRAAIDYIKHLQELLERQAWGLEGAA 140

Query: 176 AAFYAPGPLPPGRGGEHYSGDSDASSPRSNCSD 208
                 G +P  R   +  G+S ASS  S  S+
Sbjct: 141 ------GAVPQRRAECNSDGESKASSAPSPSSE 167


>gi|4507741 twist [Homo sapiens]
          Length = 202

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 23/71 (32%), Positives = 42/71 (59%)

Query: 110 RRKAATMRERRRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDA 169
           +R  A +RER+R   +NEAF  L++   + P+ +L K++ L+ A RYI+ L  +L+  + 
Sbjct: 109 QRVMANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDEL 168

Query: 170 APPGAAAAFYA 180
               A+ ++ A
Sbjct: 169 DSKMASCSYVA 179


>gi|17981708 twist homolog 2 [Homo sapiens]
          Length = 160

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 21/59 (35%), Positives = 37/59 (62%)

Query: 110 RRKAATMRERRRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQD 168
           +R  A +RER+R   +NEAF  L++   + P+ +L K++ L+ A RYI+ L  +L+  +
Sbjct: 67  QRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDE 125


>gi|21553337 atonal homolog 7 [Homo sapiens]
          Length = 152

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 26/72 (36%), Positives = 39/72 (54%), Gaps = 1/72 (1%)

Query: 98  CKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSS-NPNQRLPKVEILRNAIRY 156
           C    R  + A RR AA  RERRR+  +N AF+ L+R       +++L K E L+ A+ Y
Sbjct: 29  CAGAGRLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSY 88

Query: 157 IEGLQALLRDQD 168
           I  L  +L + +
Sbjct: 89  IMALTRILAEAE 100


>gi|23097242 nephew of atonal 3 [Homo sapiens]
          Length = 166

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 12/116 (10%)

Query: 59  PEEHSHFPAAVHPAPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRE 118
           PEE       V    G  E+E  R        GR +    +  +++     +R+AA +RE
Sbjct: 62  PEEEE---CEVDQGDGEEEEEEER--------GRGVSLLGRPKRKRVITYAQRQAANIRE 110

Query: 119 RRRLSKVNEAFETLKRCTSSNP-NQRLPKVEILRNAIRYIEGLQALLRDQDAAPPG 173
           R+R+  +NEAF+ L+R   +    +RL ++E LR AI YI  +  LL   +    G
Sbjct: 111 RKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELLESCEKKESG 166


>gi|48255909 basic helix-loop-helix transcription factor 15 [Homo
           sapiens]
          Length = 199

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 36/102 (35%), Positives = 48/102 (47%), Gaps = 12/102 (11%)

Query: 110 RRKAATMRERRRLSKVNEAFETLKRCTSSNP-NQRLPKVEILRNAIRYIEGLQALLRDQD 168
           +R+AA  RER R   VN AF  L+    + P +++L K+E LR A  YI  L  +L   D
Sbjct: 73  QRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVLLLGD 132

Query: 169 AAPPGA---AAAFYAPGPLPPGRGGEHYSGDSDASSPRSNCS 207
           +A  G     AA  A G +P    G           PRS C+
Sbjct: 133 SADDGQPCFRAAGSAKGAVPAAADG--------GRQPRSICT 166


>gi|148922889 scleraxis homolog B [Homo sapiens]
          Length = 201

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 34/97 (35%), Positives = 46/97 (47%), Gaps = 14/97 (14%)

Query: 110 RRKAATMRERRRLSKVNEAFETLKRCTSSNP-NQRLPKVEILRNAIRYIEGLQALLRDQD 168
           +R  A  RER R + VN AF  L+    + P +++L K+E LR A  YI  L  +L   +
Sbjct: 76  QRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGE 135

Query: 169 AAPPG-----AAAAFYA--------PGPLPPGRGGEH 192
           A   G       A F+A        P P PP R GE+
Sbjct: 136 ACGDGQPCHSGPAFFHAARAGSPPPPPPPPPARDGEN 172


>gi|186972126 scleraxis homolog A [Homo sapiens]
          Length = 201

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 34/97 (35%), Positives = 46/97 (47%), Gaps = 14/97 (14%)

Query: 110 RRKAATMRERRRLSKVNEAFETLKRCTSSNP-NQRLPKVEILRNAIRYIEGLQALLRDQD 168
           +R  A  RER R + VN AF  L+    + P +++L K+E LR A  YI  L  +L   +
Sbjct: 76  QRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGE 135

Query: 169 AAPPG-----AAAAFYA--------PGPLPPGRGGEH 192
           A   G       A F+A        P P PP R GE+
Sbjct: 136 ACGDGQPCHSGPAFFHAARAGSPPPPPPPPPARDGEN 172


>gi|12545384 basic helix-loop-helix transcription factor HAND2 [Homo
           sapiens]
          Length = 217

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 29/72 (40%), Positives = 37/72 (51%), Gaps = 3/72 (4%)

Query: 110 RRKAATMRERRRLSKVNEAFETLKRCTSSNP-NQRLPKVEILRNAIRYIEGLQALLRDQD 168
           RR  A  +ERRR   +N AF  L+ C  + P + +L K++ LR A  YI  L  LL   D
Sbjct: 100 RRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDD 159

Query: 169 AAPPGAAAAFYA 180
               G A AF A
Sbjct: 160 --QNGEAEAFKA 169


>gi|31077092 neurogenin 2 [Homo sapiens]
          Length = 272

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 35/103 (33%), Positives = 43/103 (41%), Gaps = 5/103 (4%)

Query: 110 RRKAATMRERRRLSKVNEAFETLKRCTSSNPNQ-RLPKVEILRNAIRYIEGLQALLRDQD 168
           RR  A  RER R+  +N A + L+    + P   +L K+E LR A  YI  L   LR  D
Sbjct: 113 RRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLAD 172

Query: 169 AAPPGA----AAAFYAPGPLPPGRGGEHYSGDSDASSPRSNCS 207
               G      A F     L PG      S   D+ SP S  S
Sbjct: 173 HCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPASTWS 215


>gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]
          Length = 108

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 29/79 (36%), Positives = 40/79 (50%), Gaps = 1/79 (1%)

Query: 110 RRKAATMRERRRLSKVNEAFETLKRCTSSNP-NQRLPKVEILRNAIRYIEGLQALLRDQD 168
           R+     RER R   VN AF  L++   ++P +++L K E LR A+RYI  L  +L +Q 
Sbjct: 3   RKIFTNTRERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGEQS 62

Query: 169 AAPPGAAAAFYAPGPLPPG 187
               G AA     G  P G
Sbjct: 63  LQQTGVAAQGNILGLFPQG 81


>gi|68989258 neurogenin 3 [Homo sapiens]
          Length = 214

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 34/98 (34%), Positives = 43/98 (43%), Gaps = 6/98 (6%)

Query: 110 RRKAATMRERRRLSKVNEAFETLKRCTSSNPNQ-RLPKVEILRNAIRYIEGLQALLRDQD 168
           RRK A  RER R+  +N A + L+    + P+  +L K+E LR A  YI  L   LR  D
Sbjct: 84  RRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIAD 143

Query: 169 AA-----PPGAAAAFYAPGPLPPGRGGEHYSGDSDASS 201
            +     PP             PG  G  YS  S A S
Sbjct: 144 HSLYALEPPAPHCGELGSPGGSPGDWGSLYSPVSQAGS 181


>gi|116517330 factor in the germline alpha [Homo sapiens]
          Length = 219

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 23/57 (40%), Positives = 31/57 (54%), Gaps = 1/57 (1%)

Query: 109 DRRKAATMRERRRLSKVNEAFETLKRCTSSNPNQRLP-KVEILRNAIRYIEGLQALL 164
           +RR+ A  +ER R+  +N  F  LK      P  R P KV+IL+ A  YI+ L  LL
Sbjct: 65  ERRRVANAKERERIKNLNRGFARLKALVPFLPQSRKPSKVDILKGATEYIQVLSDLL 121


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,447,065
Number of Sequences: 37866
Number of extensions: 956498
Number of successful extensions: 4805
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 76
Number of HSP's successfully gapped in prelim test: 312
Number of HSP's that attempted gapping in prelim test: 4398
Number of HSP's gapped (non-prelim): 701
length of query: 320
length of database: 18,247,518
effective HSP length: 102
effective length of query: 218
effective length of database: 14,385,186
effective search space: 3135970548
effective search space used: 3135970548
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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