Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 229892302
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|229892302 fms-related tyrosine kinase 1 isoform 4 precursor
[Homo sapiens]
(541 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|229892302 fms-related tyrosine kinase 1 isoform 4 precursor [... 1099 0.0
gi|156104876 fms-related tyrosine kinase 1 isoform 1 precursor [... 1049 0.0
gi|229892220 fms-related tyrosine kinase 1 isoform 2 precursor [... 1049 0.0
gi|229892300 fms-related tyrosine kinase 1 isoform 3 precursor [... 1049 0.0
gi|11321597 kinase insert domain receptor precursor [Homo sapiens] 271 1e-72
gi|104294888 fms-related tyrosine kinase 4 isoform 1 precursor [... 268 9e-72
gi|103472027 fms-related tyrosine kinase 4 isoform 2 precursor [... 268 9e-72
gi|5453870 platelet-derived growth factor receptor alpha precurs... 143 5e-34
gi|4505683 platelet-derived growth factor receptor beta precurso... 108 2e-23
gi|148005039 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncoge... 93 5e-19
gi|4557695 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene... 93 5e-19
gi|5453872 platelet-derived growth factor receptor-like protein ... 92 2e-18
gi|118572606 hemicentin 1 [Homo sapiens] 84 4e-16
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 73 8e-13
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 72 2e-12
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 72 2e-12
gi|7657359 contactin 5 isoform long [Homo sapiens] 68 2e-11
gi|28373129 contactin 5 isoform short [Homo sapiens] 68 2e-11
gi|27262659 colony stimulating factor 1 receptor precursor [Homo... 65 1e-10
gi|126517478 peroxidasin homolog-like [Homo sapiens] 65 1e-10
gi|110431348 deleted in colorectal carcinoma [Homo sapiens] 61 3e-09
gi|109150416 peroxidasin [Homo sapiens] 60 5e-09
gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo ... 60 7e-09
gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo s... 60 7e-09
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 60 7e-09
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 60 7e-09
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 60 7e-09
gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sap... 59 9e-09
gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens] 59 9e-09
gi|142976733 surface glycoprotein, Ig superfamily member [Homo s... 59 9e-09
>gi|229892302 fms-related tyrosine kinase 1 isoform 4 precursor
[Homo sapiens]
Length = 541
Score = 1099 bits (2843), Expect = 0.0
Identities = 541/541 (100%), Positives = 541/541 (100%)
Query: 1 MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHK 60
MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHK
Sbjct: 1 MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHK 60
Query: 61 WSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKET 120
WSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKET
Sbjct: 61 WSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKET 120
Query: 121 ESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPD 180
ESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPD
Sbjct: 121 ESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPD 180
Query: 181 GKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV 240
GKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV
Sbjct: 181 GKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV 240
Query: 241 KLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDK 300
KLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDK
Sbjct: 241 KLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDK 300
Query: 301 MQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK 360
MQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK
Sbjct: 301 MQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK 360
Query: 361 AFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTA 420
AFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTA
Sbjct: 361 AFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTA 420
Query: 421 TLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARC 480
TLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARC
Sbjct: 421 TLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARC 480
Query: 481 DFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNKLPPANSSFMLPPTSFSSNYFHFL 540
DFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNKLPPANSSFMLPPTSFSSNYFHFL
Sbjct: 481 DFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNKLPPANSSFMLPPTSFSSNYFHFL 540
Query: 541 P 541
P
Sbjct: 541 P 541
>gi|156104876 fms-related tyrosine kinase 1 isoform 1 precursor
[Homo sapiens]
Length = 1338
Score = 1049 bits (2713), Expect = 0.0
Identities = 517/518 (99%), Positives = 518/518 (100%)
Query: 1 MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHK 60
MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHK
Sbjct: 1 MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHK 60
Query: 61 WSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKET 120
WSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKET
Sbjct: 61 WSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKET 120
Query: 121 ESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPD 180
ESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPD
Sbjct: 121 ESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPD 180
Query: 181 GKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV 240
GKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV
Sbjct: 181 GKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV 240
Query: 241 KLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDK 300
KLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDK
Sbjct: 241 KLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDK 300
Query: 301 MQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK 360
MQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK
Sbjct: 301 MQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK 360
Query: 361 AFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTA 420
AFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTA
Sbjct: 361 AFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTA 420
Query: 421 TLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARC 480
TLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARC
Sbjct: 421 TLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARC 480
Query: 481 DFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNKL 518
DFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNK+
Sbjct: 481 DFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNKM 518
Score = 49.7 bits (117), Expect = 7e-06
Identities = 50/169 (29%), Positives = 69/169 (40%), Gaps = 19/169 (11%)
Query: 245 GHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSV---LTIDKM 301
G L L+CT L V TW N R ++ I + +S+ LTI +
Sbjct: 570 GEDLKLSCTVNKFLYRDV--TWILLRTVNNR-TMHYSISKQKMAITKEHSITLNLTIMNV 626
Query: 302 QNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVL------ETVAGKRSYRL 355
+D G Y CR R+ V T I K IT++ ++ L TVA S L
Sbjct: 627 SLQDSGTYACRARN------VYTGEEILQKKEITIRDQEAPYLLRNLSDHTVAISSSTTL 680
Query: 356 SMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYS-LIIKDVTEEDAGNY 403
P P++ W K+ ++ L G S L I+ VTEED G Y
Sbjct: 681 DCHANGVPEPQITWFKNNHKIQQEPGIILGPGSSTLFIERVTEEDEGVY 729
Score = 47.4 bits (111), Expect = 3e-05
Identities = 98/489 (20%), Positives = 179/489 (36%), Gaps = 85/489 (17%)
Query: 32 PELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPEMVSKE-SERLSITKSACGRNGKQFCS 90
P L+G ++ T L R + WS P+ +K S R I +S N F S
Sbjct: 239 PVKLLRGHTLVLNCTATTPLNTRVQMT--WSYPDEKNKRASVRRRIDQSNSHAN--IFYS 294
Query: 91 TLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTE 150
LT++ Q G Y+C+ + P+ K T IY + F+ + +++
Sbjct: 295 VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIY------DKAFITVKHRKQQVLETVA 348
Query: 151 GRELVIPCRVTSPNITVTLKKFPLDTLI--PDGKRIIWDSRK------GFIISNATYKEI 202
G+ S +++ +K FP ++ DG S + II + T ++
Sbjct: 349 GKR--------SYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDA 400
Query: 203 GLLTCEATVNGHLYKTNYLTHRQTNTIIDVQ--------ISTPRPVKLLRGHTLVLNCTA 254
G T ++ ++N + I++V+ S P P G +L CTA
Sbjct: 401 GNYTILLSIK----QSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTA 456
Query: 255 TTPLNTRVQMTWSYPDEKNKRA------------------SVRRRIDQSNSHANIFYS-- 294
++ W + + A ++ RI+ I
Sbjct: 457 YGIPQPTIKWFWHPCNHNHSEARCDFCSNNEESFILDADSNMGNRIESITQRMAIIEGKN 516
Query: 295 --VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGK-R 351
T+ ++ G+Y C + N S +I D V + LE + +
Sbjct: 517 KMASTLVVADSRISGIYICIASNKVGTVGRNISFYITD-----VPNGFHVNLEKMPTEGE 571
Query: 352 SYRLSMKVKAFPSPEVVWL-------KDGLPATEKSARYLTRGYS----LIIKDVTEEDA 400
+LS V F +V W+ + + K +T+ +S L I +V+ +D+
Sbjct: 572 DLKLSCTVNKFLYRDVTWILLRTVNNRTMHYSISKQKMAITKEHSITLNLTIMNVSLQDS 631
Query: 401 GNYTILLSIKQSNVF--KNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYG 458
G Y + + NV+ + + + ++ Q + + D + + S L C A G
Sbjct: 632 GTY----ACRARNVYTGEEILQKKEITIRDQEAPYLLRNLSDHTV-AISSSTTLDCHANG 686
Query: 459 IPQPTIKWF 467
+P+P I WF
Sbjct: 687 VPEPQITWF 695
Score = 34.3 bits (77), Expect = 0.30
Identities = 58/277 (20%), Positives = 108/277 (38%), Gaps = 45/277 (16%)
Query: 75 SITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRP 134
SIT+ GK ++ TL A + +G Y C + ++K I +I+D
Sbjct: 504 SITQRMAIIEGKNKMAS-TLVVADSRISGIYIC----IASNKVGTVGRNISFYITDVPNG 558
Query: 135 FVEMYSEIPEIIHMTEGRELVIPCRVTS---PNITV----TLKKFPLDTLIPDGKRIIWD 187
F ++P TEG +L + C V ++T T+ + I K I
Sbjct: 559 FHVNLEKMP-----TEGEDLKLSCTVNKFLYRDVTWILLRTVNNRTMHYSISKQKMAITK 613
Query: 188 SRK---GFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLR 244
I N + ++ G C A ++Y + ++ TI D + P ++ L
Sbjct: 614 EHSITLNLTIMNVSLQDSGTYACRAR---NVYTGEEILQKKEITIRDQE--APYLLRNLS 668
Query: 245 GHTLVLNCTATTPLNTR----VQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDK 300
HT+ ++ + T + Q+TW + N + I + +F I++
Sbjct: 669 DHTVAISSSTTLDCHANGVPEPQITWF---KNNHKIQQEPGIILGPGSSTLF-----IER 720
Query: 301 MQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVK 337
+ +D+G+Y C K+ N + A++TV+
Sbjct: 721 VTEEDEGVYHC--------KATNQKGSVESSAYLTVQ 749
>gi|229892220 fms-related tyrosine kinase 1 isoform 2 precursor
[Homo sapiens]
Length = 687
Score = 1049 bits (2713), Expect = 0.0
Identities = 517/518 (99%), Positives = 518/518 (100%)
Query: 1 MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHK 60
MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHK
Sbjct: 1 MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHK 60
Query: 61 WSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKET 120
WSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKET
Sbjct: 61 WSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKET 120
Query: 121 ESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPD 180
ESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPD
Sbjct: 121 ESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPD 180
Query: 181 GKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV 240
GKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV
Sbjct: 181 GKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV 240
Query: 241 KLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDK 300
KLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDK
Sbjct: 241 KLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDK 300
Query: 301 MQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK 360
MQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK
Sbjct: 301 MQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK 360
Query: 361 AFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTA 420
AFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTA
Sbjct: 361 AFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTA 420
Query: 421 TLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARC 480
TLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARC
Sbjct: 421 TLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARC 480
Query: 481 DFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNKL 518
DFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNK+
Sbjct: 481 DFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNKM 518
>gi|229892300 fms-related tyrosine kinase 1 isoform 3 precursor
[Homo sapiens]
Length = 733
Score = 1049 bits (2713), Expect = 0.0
Identities = 517/518 (99%), Positives = 518/518 (100%)
Query: 1 MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHK 60
MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHK
Sbjct: 1 MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHK 60
Query: 61 WSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKET 120
WSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKET
Sbjct: 61 WSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKET 120
Query: 121 ESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPD 180
ESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPD
Sbjct: 121 ESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPD 180
Query: 181 GKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV 240
GKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV
Sbjct: 181 GKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV 240
Query: 241 KLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDK 300
KLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDK
Sbjct: 241 KLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDK 300
Query: 301 MQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK 360
MQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK
Sbjct: 301 MQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK 360
Query: 361 AFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTA 420
AFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTA
Sbjct: 361 AFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTA 420
Query: 421 TLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARC 480
TLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARC
Sbjct: 421 TLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARC 480
Query: 481 DFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNKL 518
DFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNK+
Sbjct: 481 DFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNKM 518
Score = 47.4 bits (111), Expect = 3e-05
Identities = 98/489 (20%), Positives = 179/489 (36%), Gaps = 85/489 (17%)
Query: 32 PELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPEMVSKE-SERLSITKSACGRNGKQFCS 90
P L+G ++ T L R + WS P+ +K S R I +S N F S
Sbjct: 239 PVKLLRGHTLVLNCTATTPLNTRVQMT--WSYPDEKNKRASVRRRIDQSNSHAN--IFYS 294
Query: 91 TLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTE 150
LT++ Q G Y+C+ + P+ K T IY + F+ + +++
Sbjct: 295 VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIY------DKAFITVKHRKQQVLETVA 348
Query: 151 GRELVIPCRVTSPNITVTLKKFPLDTLI--PDGKRIIWDSRK------GFIISNATYKEI 202
G+ S +++ +K FP ++ DG S + II + T ++
Sbjct: 349 GKR--------SYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDA 400
Query: 203 GLLTCEATVNGHLYKTNYLTHRQTNTIIDVQ--------ISTPRPVKLLRGHTLVLNCTA 254
G T ++ ++N + I++V+ S P P G +L CTA
Sbjct: 401 GNYTILLSIK----QSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTA 456
Query: 255 TTPLNTRVQMTWSYPDEKNKRA------------------SVRRRIDQSNSHANIFYS-- 294
++ W + + A ++ RI+ I
Sbjct: 457 YGIPQPTIKWFWHPCNHNHSEARCDFCSNNEESFILDADSNMGNRIESITQRMAIIEGKN 516
Query: 295 --VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGK-R 351
T+ ++ G+Y C + N S +I D V + LE + +
Sbjct: 517 KMASTLVVADSRISGIYICIASNKVGTVGRNISFYITD-----VPNGFHVNLEKMPTEGE 571
Query: 352 SYRLSMKVKAFPSPEVVWL-------KDGLPATEKSARYLTRGYS----LIIKDVTEEDA 400
+LS V F +V W+ + + K +T+ +S L I +V+ +D+
Sbjct: 572 DLKLSCTVNKFLYRDVTWILLRTVNNRTMHYSISKQKMAITKEHSITLNLTIMNVSLQDS 631
Query: 401 GNYTILLSIKQSNVF--KNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYG 458
G Y + + NV+ + + + ++ Q + + D + + S L C A G
Sbjct: 632 GTY----ACRARNVYTGEEILQKKEITIRDQEAPYLLRNLSDHTV-AISSSTTLDCHANG 686
Query: 459 IPQPTIKWF 467
+P+P I WF
Sbjct: 687 VPEPQITWF 695
Score = 38.5 bits (88), Expect = 0.016
Identities = 38/137 (27%), Positives = 54/137 (39%), Gaps = 18/137 (13%)
Query: 245 GHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSV---LTIDKM 301
G L L+CT L V TW N R ++ I + +S+ LTI +
Sbjct: 570 GEDLKLSCTVNKFLYRDV--TWILLRTVNNR-TMHYSISKQKMAITKEHSITLNLTIMNV 626
Query: 302 QNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVL------ETVAGKRSYRL 355
+D G Y CR R +V T I K IT++ ++ L TVA S L
Sbjct: 627 SLQDSGTYACRAR------NVYTGEEILQKKEITIRDQEAPYLLRNLSDHTVAISSSTTL 680
Query: 356 SMKVKAFPSPEVVWLKD 372
P P++ W K+
Sbjct: 681 DCHANGVPEPQITWFKN 697
>gi|11321597 kinase insert domain receptor precursor [Homo sapiens]
Length = 1356
Score = 271 bits (692), Expect = 1e-72
Identities = 177/522 (33%), Positives = 265/522 (50%), Gaps = 28/522 (5%)
Query: 9 VLLCALLSCLLLTGSSSGS---KLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPE 65
+L AL C+ +S G L P LS++ ++A TL + CRG+ W P
Sbjct: 6 LLAVALWLCVETRAASVGLPSVSLDLPRLSIQKDILTIKANTTLQITCRGQRDLDWLWPN 65
Query: 66 MVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIY 125
S +R+ +T+ + G FC TLT+ N TG Y C Y ++ + S IY
Sbjct: 66 NQSGSEQRVEVTECSDGL----FCKTLTIPKVIGNDTGAYKCFY------RETDLASVIY 115
Query: 126 IFISDTGRPFVEMYSEIPEIIHMTEGRE--LVIPCRVTSPNITVTL-KKFPLDTLIPDGK 182
+++ D PF+ S+ ++++TE + +VIPC + N+ V+L ++P +PDG
Sbjct: 116 VYVQDYRSPFIASVSDQHGVVYITENKNKTVVIPCLGSISNLNVSLCARYPEKRFVPDGN 175
Query: 183 RIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKT-NYLTHRQTNTIIDVQISTPRPVK 241
RI WDS+KGF I + G++ CEA +N Y++ Y+ I DV +S ++
Sbjct: 176 RISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRIYDVVLSPSHGIE 235
Query: 242 LLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRI--DQSNSHANIFYSVLTID 299
L G LVLNCTA T LN + W YP K++ + R QS S F S LTID
Sbjct: 236 LSVGEKLVLNCTARTELNVGIDFNWEYPSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTID 295
Query: 300 KMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKV 359
+ D+GLYTC SG K +T V +++K F+ + ++E G+R R+ K
Sbjct: 296 GVTRSDQGLYTCAASSGLMTKKNSTFVRVHEKPFVAFGSGMESLVEATVGER-VRIPAKY 354
Query: 360 KAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLT 419
+P PE+ W K+G+P +S + G+ L I +V+E D GNYT++L+ S ++
Sbjct: 355 LGYPPPEIKWYKNGIPL--ESNHTIKAGHVLTIMEVSERDTGNYTVILTNPISKEKQSHV 412
Query: 420 ATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQP-TIKWFW---HPCNHNH 475
+L+V V PQI EK++ S D Y G+ Q LTCT Y IP P I W+W C +
Sbjct: 413 VSLVVYVPPQIGEKSLISPVDS--YQYGTTQTLTCTVYAIPPPHHIHWYWQLEEECANEP 470
Query: 476 SEARCDFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNK 517
S+A E + D GN+IE + A+IEGKNK
Sbjct: 471 SQAVSVTNPYPCEEWRSVEDFQGGNKIEVNKNQFALIEGKNK 512
Score = 35.8 bits (81), Expect = 0.10
Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 7/123 (5%)
Query: 285 SNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKS--VNTSVHIYDKAFITVKHRKQQ 342
SNS +I ++ + +D+G Y C + + K V + + ++ T+ +
Sbjct: 618 SNSTNDIL--IMELKNASLQDQGDYVCLAQDRKTKKRHCVVRQLTVLERVAPTITGNLEN 675
Query: 343 VLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRG-YSLIIKDVTEEDAG 401
+T + S +S P P+++W KD E S L G +L I+ V +ED G
Sbjct: 676 --QTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVLKDGNRNLTIRRVRKEDEG 733
Query: 402 NYT 404
YT
Sbjct: 734 LYT 736
>gi|104294888 fms-related tyrosine kinase 4 isoform 1 precursor
[Homo sapiens]
Length = 1363
Score = 268 bits (685), Expect = 9e-72
Identities = 164/529 (31%), Positives = 264/529 (49%), Gaps = 35/529 (6%)
Query: 8 GVLLCALL-SCL-LLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHKWS--- 62
G LC L CL LL G SG + P L++ H++ G +L + CRG+ +W+
Sbjct: 4 GAALCLRLWLCLGLLDGLVSGYSMTPPTLNITEESHVIDTGDSLSISCRGQHPLEWAWPG 63
Query: 63 ---LPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKE 119
P K+SE + + G + + +C L L+ AN TG Y C Y + +
Sbjct: 64 AQEAPATGDKDSEDTGVVRDCEGTDARPYCKVLLLHEVHANDTGSYVCYYKYIKARIEGT 123
Query: 120 TESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIP 179
T ++ Y+F+ D +PF+ P+ + + + +PC V+ P + VTL+ L P
Sbjct: 124 TAASSYVFVRDFEQPFINK----PDTLLVNRKDAMWVPCLVSIPGLNVTLRS-QSSVLWP 178
Query: 180 DGKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTN-YLTHRQTNTIIDVQISTPR 238
DG+ ++WD R+G ++S + L CE T + +N +L H N + D+Q+ +
Sbjct: 179 DGQEVVWDDRRGMLVSTPLLHDALYLQCETTWGDQDFLSNPFLVHITGNELYDIQLLPRK 238
Query: 239 PVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRAS--VRRRIDQSNSHANIFYSVL 296
++LL G LVLNCT N+ V W YP ++ +R RR Q+++ + S+L
Sbjct: 239 SLELLVGEKLVLNCTVWAEFNSGVTFDWDYPGKQAERGKWVPERRSQQTHTELS---SIL 295
Query: 297 TIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLS 356
TI + D G Y C+ +G +T V +++ FI+V+ K +LE AG +L
Sbjct: 296 TIHNVSQHDLGSYVCKANNGIQRFRESTEVIVHENPFISVEWLKGPILEATAGDELVKLP 355
Query: 357 MKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFK 416
+K+ A+P PE W KDG + + + ++L++K+VTE G YT+ L + + +
Sbjct: 356 VKLAAYPPPEFQWYKDGKALSGRHS-----PHALVLKEVTEASTGTYTLALWNSAAGLRR 410
Query: 417 NLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQP-TIKWFWHPCNHNH 475
N++ L+VNV PQI+EK SS P++Y SRQ LTCTAYG+P P +I+W W P
Sbjct: 411 NISLELVVNVPPQIHEKEASS---PSIYSRHSRQALTCTAYGVPLPLSIQWHWRPWTPCK 467
Query: 476 SEARCDFCSNNEESFILD-------ADSNMGNRIESITQRMAIIEGKNK 517
A+ ++ + + N IES+ +EGKNK
Sbjct: 468 MFAQRSLRRRQQQDLMPQCRDWRAVTTQDAVNPIESLDTWTEFVEGKNK 516
Score = 33.5 bits (75), Expect = 0.51
Identities = 34/130 (26%), Positives = 54/130 (41%), Gaps = 3/130 (2%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
L+I ++ + +G Y C V+ S ++ +A + + V S +
Sbjct: 638 LSIPRVAPEHEGHYVCEVQDRRSHDKHCHKKYLSVQALEAPRLTQNLTDLLVNVSDSLEM 697
Query: 356 SMKVKAFPSPEVVWLKDGLPATEKSARYLT-RGYSLIIKDVTEEDAGNYTILLSIKQSNV 414
V +P +VW KD EKS L L I+ V EEDAG Y L S+ +
Sbjct: 698 QCLVAGAHAPSIVWYKDERLLEEKSGVDLADSNQKLSIQRVREEDAGRY--LCSVCNAKG 755
Query: 415 FKNLTATLIV 424
N +A++ V
Sbjct: 756 CVNSSASVAV 765
>gi|103472027 fms-related tyrosine kinase 4 isoform 2 precursor
[Homo sapiens]
Length = 1298
Score = 268 bits (685), Expect = 9e-72
Identities = 164/529 (31%), Positives = 264/529 (49%), Gaps = 35/529 (6%)
Query: 8 GVLLCALL-SCL-LLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHKWS--- 62
G LC L CL LL G SG + P L++ H++ G +L + CRG+ +W+
Sbjct: 4 GAALCLRLWLCLGLLDGLVSGYSMTPPTLNITEESHVIDTGDSLSISCRGQHPLEWAWPG 63
Query: 63 ---LPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKE 119
P K+SE + + G + + +C L L+ AN TG Y C Y + +
Sbjct: 64 AQEAPATGDKDSEDTGVVRDCEGTDARPYCKVLLLHEVHANDTGSYVCYYKYIKARIEGT 123
Query: 120 TESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIP 179
T ++ Y+F+ D +PF+ P+ + + + +PC V+ P + VTL+ L P
Sbjct: 124 TAASSYVFVRDFEQPFINK----PDTLLVNRKDAMWVPCLVSIPGLNVTLRS-QSSVLWP 178
Query: 180 DGKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTN-YLTHRQTNTIIDVQISTPR 238
DG+ ++WD R+G ++S + L CE T + +N +L H N + D+Q+ +
Sbjct: 179 DGQEVVWDDRRGMLVSTPLLHDALYLQCETTWGDQDFLSNPFLVHITGNELYDIQLLPRK 238
Query: 239 PVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRAS--VRRRIDQSNSHANIFYSVL 296
++LL G LVLNCT N+ V W YP ++ +R RR Q+++ + S+L
Sbjct: 239 SLELLVGEKLVLNCTVWAEFNSGVTFDWDYPGKQAERGKWVPERRSQQTHTELS---SIL 295
Query: 297 TIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLS 356
TI + D G Y C+ +G +T V +++ FI+V+ K +LE AG +L
Sbjct: 296 TIHNVSQHDLGSYVCKANNGIQRFRESTEVIVHENPFISVEWLKGPILEATAGDELVKLP 355
Query: 357 MKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFK 416
+K+ A+P PE W KDG + + + ++L++K+VTE G YT+ L + + +
Sbjct: 356 VKLAAYPPPEFQWYKDGKALSGRHS-----PHALVLKEVTEASTGTYTLALWNSAAGLRR 410
Query: 417 NLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQP-TIKWFWHPCNHNH 475
N++ L+VNV PQI+EK SS P++Y SRQ LTCTAYG+P P +I+W W P
Sbjct: 411 NISLELVVNVPPQIHEKEASS---PSIYSRHSRQALTCTAYGVPLPLSIQWHWRPWTPCK 467
Query: 476 SEARCDFCSNNEESFILD-------ADSNMGNRIESITQRMAIIEGKNK 517
A+ ++ + + N IES+ +EGKNK
Sbjct: 468 MFAQRSLRRRQQQDLMPQCRDWRAVTTQDAVNPIESLDTWTEFVEGKNK 516
Score = 33.5 bits (75), Expect = 0.51
Identities = 34/130 (26%), Positives = 54/130 (41%), Gaps = 3/130 (2%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
L+I ++ + +G Y C V+ S ++ +A + + V S +
Sbjct: 638 LSIPRVAPEHEGHYVCEVQDRRSHDKHCHKKYLSVQALEAPRLTQNLTDLLVNVSDSLEM 697
Query: 356 SMKVKAFPSPEVVWLKDGLPATEKSARYLT-RGYSLIIKDVTEEDAGNYTILLSIKQSNV 414
V +P +VW KD EKS L L I+ V EEDAG Y L S+ +
Sbjct: 698 QCLVAGAHAPSIVWYKDERLLEEKSGVDLADSNQKLSIQRVREEDAGRY--LCSVCNAKG 755
Query: 415 FKNLTATLIV 424
N +A++ V
Sbjct: 756 CVNSSASVAV 765
>gi|5453870 platelet-derived growth factor receptor alpha precursor
[Homo sapiens]
Length = 1089
Score = 143 bits (360), Expect = 5e-34
Identities = 147/521 (28%), Positives = 229/521 (43%), Gaps = 62/521 (11%)
Query: 14 LLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPEMVSKESER 73
+L CLL S +L P + + ++Q + L+C GE+ W P M +ES
Sbjct: 10 VLGCLLTGLSLILCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYP-MSEEESSD 68
Query: 74 LSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGR 133
+ I N F + L +++A A HTG Y+C Y T + + IYI++ D
Sbjct: 69 VEIRNEE--NNSGLFVTVLEVSSASAAHTGLYTCYYNHTQTEENELEGRHIYIYVPDPDV 126
Query: 134 PFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPDGKRIIWDSRKGFI 193
FV + ++ + + +IPCR T P VTL + ++P +DSR+GF
Sbjct: 127 AFVPL-GMTDYLVIVEDDDSAIIPCRTTDPETPVTLHN--SEGVVPAS----YDSRQGF- 178
Query: 194 ISNATYKEIGLLTCEATVNGHLYKT---NYLTHRQTNTIIDVQISTPRPVKLLRGHTLVL 250
N T+ +G CEATV G ++T N + T+ +D+++ + V G T+V+
Sbjct: 179 --NGTF-TVGPYICEATVKGKKFQTIPFNVYALKATSE-LDLEMEALKTV-YKSGETIVV 233
Query: 251 NCTATTPLNTRVQMTWSYPDE-KNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLY 309
C N V + W+YP E K K ++ I + + Y+ LT+ + KD G Y
Sbjct: 234 TCAVFN--NEVVDLQWTYPGEVKGKGITMLEEIKVPS--IKLVYT-LTVPEATVKDSGDY 288
Query: 310 TCRVRSG----PSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSP 365
C R K V SVH +K FI +K Q LE V ++V+A+P P
Sbjct: 289 ECAARQATREVKEMKKVTISVH--EKGFIEIKPTFSQ-LEAVNLHEVKHFVVEVRAYPPP 345
Query: 366 EVVWLKDGLPATEKSARYLT----------RGYSLIIKDVTEEDAGNYTILLSIKQSNVF 415
+ WLK+ L E T R +I+ EED+G+YTI+ + +
Sbjct: 346 RISWLKNNLTLIENLTEITTDVEKIQEIRYRSKLKLIR-AKEEDSGHYTIV--AQNEDAV 402
Query: 416 KNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNH 475
K+ T L+ V I + + Q + CTA G P P I+W C
Sbjct: 403 KSYTFELLTQVPSSILDLVDDH------HGSTGGQTVRCTAEGTPLPDIEWM--ICK--- 451
Query: 476 SEARCDFCSNNEESFILDADSNMGNRIESITQR-MAIIEGK 515
+C NNE S+ + A +N+ N I I R + +EG+
Sbjct: 452 DIKKC----NNETSWTILA-NNVSNIITEIHSRDRSTVEGR 487
>gi|4505683 platelet-derived growth factor receptor beta precursor
[Homo sapiens]
Length = 1106
Score = 108 bits (269), Expect = 2e-23
Identities = 127/478 (26%), Positives = 205/478 (42%), Gaps = 62/478 (12%)
Query: 8 GVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPEMV 67
G LL L LL S G + P G + ++ T L C G A W E +
Sbjct: 14 GELLLLSLLLLLEPQISQGLVVTPP-----GPELVLNVSSTFVLTCSGSAPVVW---ERM 65
Query: 68 SKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESA--IY 125
S+E + + A ++G F S LTL TG Y C + S+ ET+ +Y
Sbjct: 66 SQEPPQ----EMAKAQDGT-FSSVLTLTNLTGLDTGEYFCTH---NDSRGLETDERKRLY 117
Query: 126 IFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPDGKRII 185
IF+ D F+ +E I +TE E+ IPCRVT P + VTL + D +P +
Sbjct: 118 IFVPDPTVGFLPNDAE-ELFIFLTEITEITIPCRVTDPQLVVTLHEKKGDVALP----VP 172
Query: 186 WDSRKGF--IISNATYKEIGLLTCEATVNGHLYKTN-YLTHRQTNTIIDVQISTPRPVKL 242
+D ++GF I + +Y C+ T+ ++ Y +R + I+V ++ + V +
Sbjct: 173 YDHQRGFSGIFEDRSY------ICKTTIGDREVDSDAYYVYRLQVSSINVSVNAVQTV-V 225
Query: 243 LRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQ 302
+G + L C N V W+YP +++ R V D S+L I +
Sbjct: 226 RQGENITLMCIVIG--NEVVNFEWTYPRKESGRL-VEPVTDFLLDMPYHIRSILHIPSAE 282
Query: 303 NKDKGLYTCRVRSG----PSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMK 358
+D G YTC V K++N + + + ++ + + L+ RS L +
Sbjct: 283 LEDSGTYTCNVTESVNDHQDEKAIN--ITVVESGYVRLL-GEVGTLQFAELHRSRTLQVV 339
Query: 359 VKAFPSPEVVWLKDGLPATEKSARYL---TRGYS-------LIIKDVTEEDAGNYTILLS 408
+A+P P V+W KD + SA + TR S L + V +AG+YT+
Sbjct: 340 FEAYPPPTVLWFKDNRTLGDSSAGEIALSTRNVSETRYVSELTLVRVKVAEAGHYTMRAF 399
Query: 409 IKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+ + V L+ L +NV ++ E + S +P Q + C G+PQP I W
Sbjct: 400 HEDAEV--QLSFQLQINVPVRVLELSES-------HPDSGEQTVRCRGRGMPQPNIIW 448
>gi|148005039 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene
homolog isoform 2 precursor [Homo sapiens]
Length = 972
Score = 93.2 bits (230), Expect = 5e-19
Identities = 122/500 (24%), Positives = 207/500 (41%), Gaps = 81/500 (16%)
Query: 5 WDTGVLLCALLSCLLL-TGSSSGS----KLKDPELSLKGTQHIMQAGQTLHLQCRGEAAH 59
WD LC LL L + TGSS S + P + + I++ G + L C
Sbjct: 8 WD---FLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTDPGFV 64
Query: 60 KWSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKE 119
KW+ E++ + +E KQ + A+A +TG Y+C + K
Sbjct: 65 KWTF-EILDETNEN------------KQ--NEWITEKAEATNTGKYTC-------TNKHG 102
Query: 120 TESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIP 179
++IY+F+ D + F+ + ++ E + ++ C +T P +T K +P
Sbjct: 103 LSNSIYVFVRDPAKLFL-----VDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLP 157
Query: 180 DGKRIIWDSRKGFIISNA--TYKEIGLLTCEATVNGH--LYKTNYLTHRQTNTIIDVQIS 235
R I D + G +I + Y + L C G L + L R + V +S
Sbjct: 158 KDLRFIPDPKAGIMIKSVKRAYHRL-CLHCSVDQEGKSVLSEKFILKVRPAFKAVPV-VS 215
Query: 236 TPRPVKLLR-GHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFY- 293
+ LLR G + CT +++ V TW +N + ++ + + S H + Y
Sbjct: 216 VSKASYLLREGEEFTVTCTIKD-VSSSVYSTWK---RENSQTKLQEKYN-SWHHGDFNYE 270
Query: 294 --SVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKR 351
+ LTI + D G++ C + +V T++ + DK FI + + G+
Sbjct: 271 RQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVDKGFINIFPMINTTVFVNDGE- 329
Query: 352 SYRLSMKVKAFPSPE-VVWLKDGLPATEKSARYLTRGYSLIIKDVTE--------EDAGN 402
+ L ++ +AFP PE W+ T+K Y I+ V+E + G
Sbjct: 330 NVDLIVEYEAFPKPEHQQWIYMNRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGT 389
Query: 403 YTILLSIKQSNVFKNLTATLIVNVKPQI--YEKAVSSFPDPALYPLGSRQILTCTAYGIP 460
YT L+S S+V + + VN KP+I Y++ V+ +L C A G P
Sbjct: 390 YTFLVS--NSDVNAAIAFNVYVNTKPEILTYDRLVNG-------------MLQCVAAGFP 434
Query: 461 QPTIKWFWHPCNHNHSEARC 480
+PTI W++ P +E RC
Sbjct: 435 EPTIDWYFCP----GTEQRC 450
>gi|4557695 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene
homolog isoform 1 precursor [Homo sapiens]
Length = 976
Score = 93.2 bits (230), Expect = 5e-19
Identities = 122/500 (24%), Positives = 207/500 (41%), Gaps = 81/500 (16%)
Query: 5 WDTGVLLCALLSCLLL-TGSSSGS----KLKDPELSLKGTQHIMQAGQTLHLQCRGEAAH 59
WD LC LL L + TGSS S + P + + I++ G + L C
Sbjct: 8 WD---FLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTDPGFV 64
Query: 60 KWSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKE 119
KW+ E++ + +E KQ + A+A +TG Y+C + K
Sbjct: 65 KWTF-EILDETNEN------------KQ--NEWITEKAEATNTGKYTC-------TNKHG 102
Query: 120 TESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIP 179
++IY+F+ D + F+ + ++ E + ++ C +T P +T K +P
Sbjct: 103 LSNSIYVFVRDPAKLFL-----VDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLP 157
Query: 180 DGKRIIWDSRKGFIISNA--TYKEIGLLTCEATVNGH--LYKTNYLTHRQTNTIIDVQIS 235
R I D + G +I + Y + L C G L + L R + V +S
Sbjct: 158 KDLRFIPDPKAGIMIKSVKRAYHRL-CLHCSVDQEGKSVLSEKFILKVRPAFKAVPV-VS 215
Query: 236 TPRPVKLLR-GHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFY- 293
+ LLR G + CT +++ V TW +N + ++ + + S H + Y
Sbjct: 216 VSKASYLLREGEEFTVTCTIKD-VSSSVYSTWK---RENSQTKLQEKYN-SWHHGDFNYE 270
Query: 294 --SVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKR 351
+ LTI + D G++ C + +V T++ + DK FI + + G+
Sbjct: 271 RQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVDKGFINIFPMINTTVFVNDGE- 329
Query: 352 SYRLSMKVKAFPSPE-VVWLKDGLPATEKSARYLTRGYSLIIKDVTE--------EDAGN 402
+ L ++ +AFP PE W+ T+K Y I+ V+E + G
Sbjct: 330 NVDLIVEYEAFPKPEHQQWIYMNRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGT 389
Query: 403 YTILLSIKQSNVFKNLTATLIVNVKPQI--YEKAVSSFPDPALYPLGSRQILTCTAYGIP 460
YT L+S S+V + + VN KP+I Y++ V+ +L C A G P
Sbjct: 390 YTFLVS--NSDVNAAIAFNVYVNTKPEILTYDRLVNG-------------MLQCVAAGFP 434
Query: 461 QPTIKWFWHPCNHNHSEARC 480
+PTI W++ P +E RC
Sbjct: 435 EPTIDWYFCP----GTEQRC 450
>gi|5453872 platelet-derived growth factor receptor-like protein
[Homo sapiens]
Length = 375
Score = 91.7 bits (226), Expect = 2e-18
Identities = 79/297 (26%), Positives = 141/297 (47%), Gaps = 27/297 (9%)
Query: 45 AGQTLHLQCRGEAAHKWSLPEMVSK-ESERLSITKSACGRNGKQFCSTLTLNTAQANHTG 103
AGQT+ L+C+G WS P + + RLS+ ++ R G+ LTL + + TG
Sbjct: 88 AGQTVELRCKGSRIG-WSYPAYLDTFKDSRLSVKQNE--RYGQ-----LTLVNSTSADTG 139
Query: 104 FYSC--KYLAVPTSKKKETES-AIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRV 160
+SC + + +K E ++ + YIF ++ G FV S +++++ R+ V+PCRV
Sbjct: 140 EFSCWVQLCSGYICRKDEAKTGSTYIFFTEKGELFVPSPSYF-DVVYLNPDRQAVVPCRV 198
Query: 161 TSPNITVTL-KKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEATVNGH----- 214
T + VTL ++FP + +G I++D ++GF+ + G++ C A G
Sbjct: 199 TVLSAKVTLHREFPAKEIPANGTDIVYDMKRGFVYLQPHSEHQGVVYCRAEAGGRSQISV 258
Query: 215 LYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNK 274
Y+ Y+ + S+ K+ G + + CT + V+ TW +P +K++
Sbjct: 259 KYQLLYVAVPSGPPSTTILASSN---KVKSGDDISVLCTVLGEPDVEVEFTWIFPGQKDE 315
Query: 275 R----ASVRRRIDQSNSH-ANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSV 326
R R I + H I SV+T++ + D G Y C ++ +V T+V
Sbjct: 316 RPVTIQDTWRLIHRGLGHTTRISQSVITVEDFETIDAGYYICTAQNLQGQTTVATTV 372
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 83.6 bits (205), Expect = 4e-16
Identities = 101/380 (26%), Positives = 152/380 (40%), Gaps = 27/380 (7%)
Query: 92 LTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEG 151
L ++ A+ + YSC V + KKE +YI RP + P I +T G
Sbjct: 2254 LQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYI------RPTITNSGSHPTEIIVTRG 2307
Query: 152 RELVIPCRVTS-PNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEAT 210
+ + + C V P TVT K + G I+ D + N + G C A
Sbjct: 2308 KSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEGHILQLKNIHVSDTGRYVCVAV 2366
Query: 211 -VNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTAT-TPLNTRVQMTWSY 268
V G K L+ +II S P + ++ +++ L C A+ PL + +TW +
Sbjct: 2367 NVAGMTDKKYDLSVHAPPSIIGNHRS-PENISVVEKNSVSLTCEASGIPLPS---ITW-F 2421
Query: 269 PDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHI 328
D S RI + + + +D G YTC VR+ + + +
Sbjct: 2422 KDGWPVSLSNSVRILSGGRMLRLMQTTM-------EDAGQYTCVVRNAAGEERKIFGLSV 2474
Query: 329 YDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARY-LTRG 387
I ++ + V V K+S L+ +V P PE+ W KDG P E A + ++ G
Sbjct: 2475 LVPPHIVGENTLEDV--KVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGG 2532
Query: 388 YSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLG 447
L I +V G YT L S + K+ + +L V V P I P+ L
Sbjct: 2533 RFLQITNVQVPHTGRYTCLASSPAGH--KSRSFSLNVFVSPTIAGVGSDGNPEDVTVILN 2590
Query: 448 SRQILTCTAYGIPQPTIKWF 467
S L C AY P TI WF
Sbjct: 2591 SPTSLVCEAYSYPPATITWF 2610
Score = 79.0 bits (193), Expect = 1e-14
Identities = 106/435 (24%), Positives = 169/435 (38%), Gaps = 68/435 (15%)
Query: 91 TLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTE 150
+L + Q G Y+C V S T+ +++ P I TE
Sbjct: 4132 SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHV----------------PPRIRSTE 4175
Query: 151 GR-------ELVIPC---RVTSPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYK 200
G + ++PC + +P I L L+ GK + I+ N +
Sbjct: 4176 GHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLL--GKYTA-EPYGELILENVVLE 4232
Query: 201 EIGLLTCEAT-VNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTAT-TPL 258
+ G TC A G T LT T ++ P V L +G L L+C AT PL
Sbjct: 4233 DSGFYTCVANNAAGEDTHTVSLTVHVLPTFTEL----PGDVSLNKGEQLRLSCKATGIPL 4288
Query: 259 NTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPS 318
++TW++ + + D N H S L I+++ +D G Y C +
Sbjct: 4289 P---KLTWTFNNN-----IIPAHFDSVNGH-----SELVIERVSKEDSGTYVCTAENSVG 4335
Query: 319 FKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPAT- 377
F V++ + + + E + G L+ +VK P+P + W + G+
Sbjct: 4336 FVKAIGFVYVKEPPVFKGDYPSNWI-EPLGGNAI--LNCEVKGDPTPTIQWNRKGVDIEI 4392
Query: 378 EKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSS 437
R L G SL I EDAG+YT + + + V ++++ TL P I ++
Sbjct: 4393 SHRIRQLGNG-SLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTL---QSPPI----ITL 4444
Query: 438 FPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHS---EARCDFCSNNEESFILDA 494
P + G + IL C A G PQPTI W HS + R + SNN +I DA
Sbjct: 4445 EPVETVINAGGKIILNCQATGEPQPTITW----SRQGHSISWDDRVNVLSNN-SLYIADA 4499
Query: 495 DSNMGNRIESITQRM 509
+ E + + +
Sbjct: 4500 QKEDTSEFECVARNL 4514
Score = 68.2 bits (165), Expect = 2e-11
Identities = 97/397 (24%), Positives = 158/397 (39%), Gaps = 45/397 (11%)
Query: 84 NGKQFCS---TLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYS 140
NG Q S L L +AQ + TG Y+C + K+++ + +Y+ P M
Sbjct: 2057 NGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYV-------PPNIMGE 2109
Query: 141 EIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYK 200
E + +++ EL+ P LK L+ I ++R I +A +
Sbjct: 2110 EQNVSVLISQAVELLCQSDAIPPPTLTWLKDG--HPLLKKPGLSISENRSVLKIEDAQVQ 2167
Query: 201 EIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTP---RPVKLLRGHTLVLNCTAT-- 255
+ G TCEAT + NY N + I + ++ G+ + L C ++
Sbjct: 2168 DTGRYTCEATNVAGKTEKNY----NVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGI 2223
Query: 256 TPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYS--VLTIDKMQNKDKGLYTCRV 313
P N + W K K + V + S I L I + D LY+C
Sbjct: 2224 PPPN----LIW-----KKKGSPV---LTDSMGRVRILSGGRQLQISIAEKSDAALYSCVA 2271
Query: 314 R--SGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLK 371
+G + K N V+I + H + + V +S L +V+ P P V W+K
Sbjct: 2272 SNVAGTAKKEYNLQVYIRPTITNSGSHPTEII---VTRGKSISLECEVQGIPPPTVTWMK 2328
Query: 372 DGLPATE-KSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQI 430
DG P + K L G+ L +K++ D G Y + +++ + + + L V+ P I
Sbjct: 2329 DGHPLIKAKGVEILDEGHILQLKNIHVSDTGRY-VCVAVNVAGM-TDKKYDLSVHAPPSI 2386
Query: 431 YEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
S P+ + LTC A GIP P+I WF
Sbjct: 2387 IGNHRS--PENISVVEKNSVSLTCEASGIPLPSITWF 2421
Score = 61.2 bits (147), Expect = 2e-09
Identities = 79/333 (23%), Positives = 128/333 (38%), Gaps = 29/333 (8%)
Query: 143 PEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEI 202
P+ + + G+ + IPC + V T++ DG+ + + I AT +
Sbjct: 1177 PKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDA 1236
Query: 203 GLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKL---LRGHTLVLNCTAT-TPL 258
G+ TC AT +T H Q ++ + P + + C A TP
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTVE-DLEPPYNTTFQERVANQRIEFPCPAKGTPK 1295
Query: 259 NTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRV--RSG 316
T + W + N R R S ++L I + D G Y C +G
Sbjct: 1296 PT---IKWLH----NGRELTGREPGISILEDG---TLLVIASVTPYDNGEYICVAVNEAG 1345
Query: 317 PSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPA 376
+ + N VH+ +K ++Q +V + L +V+ PSP ++W KD +
Sbjct: 1346 TTERKYNLKVHVPP----VIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQV 1401
Query: 377 TEKSA-RYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAV 435
TE S + + G L + T EDAG Y S K N+ T+ N+ + +
Sbjct: 1402 TESSTIQTVNNGKILKLFRATPEDAGRY----SCKAINIAG--TSQKYFNIDVLVPPTII 1455
Query: 436 -SSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
++FP+ L L C G P P I WF
Sbjct: 1456 GTNFPNEVSVVLNRDVALECQVKGTPFPDIHWF 1488
Score = 61.2 bits (147), Expect = 2e-09
Identities = 87/383 (22%), Positives = 131/383 (34%), Gaps = 40/383 (10%)
Query: 92 LTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEG 151
L L A+ N G Y C + K+ + IYI S G S + + E
Sbjct: 1510 LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLEC 1569
Query: 152 RELVIPCRVTSPNITVTLKKFPLDTLIPDGKRIIWDSRKGFI-------ISNATYKEIGL 204
+P P T DG+ I+ S+ +I I A +
Sbjct: 1570 ETRGLP--------------MPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSAT 1615
Query: 205 LTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQM 264
TC + ++ +I+ ++TP +++ H+L L C A N +
Sbjct: 1616 YTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAG--NPSPIL 1673
Query: 265 TWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNT 324
TW D +A+ RI+ L I Q D+G Y C S K +
Sbjct: 1674 TW-LKDGVPVKANDNIRIEAGGKK-------LEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 325 SVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSA-RY 383
V + I + V L V P P ++WLKDG E+ +
Sbjct: 1726 EVDVLVPPAIEGGDETSYFIVMV--NNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKI 1783
Query: 384 LTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPAL 443
L G L+I + G Y + + + K T V+V P I +S
Sbjct: 1784 LLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVT--VHVPPTIKSSGLSERVVVKY 1841
Query: 444 YPLGSRQILTCTAYGIPQPTIKW 466
P+ L C A GIP P+I W
Sbjct: 1842 KPVA----LQCIANGIPNPSITW 1860
Score = 60.8 bits (146), Expect = 3e-09
Identities = 52/234 (22%), Positives = 87/234 (37%), Gaps = 20/234 (8%)
Query: 234 ISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFY 293
I P V + G VL C + ++ +TW D + A R +N
Sbjct: 523 IQVPNNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEPARIRTLANLS----- 575
Query: 294 SVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSY 353
L + ++ D G Y C V S + + + + + +TV + Q + G
Sbjct: 576 --LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQ----SFTGGSEV 629
Query: 354 RLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSN 413
+ +P P++ W + + +T +L IK+ +DAG Y L S
Sbjct: 630 SIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGT 689
Query: 414 VFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
+N T I K + + + L LG ++ C GIP P +KWF
Sbjct: 690 DKQNSTLRYIEAPKLMVVQSEL-------LVALGDITVMECKTSGIPPPQVKWF 736
Score = 59.7 bits (143), Expect = 7e-09
Identities = 97/405 (23%), Positives = 150/405 (37%), Gaps = 63/405 (15%)
Query: 92 LTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSE-IPEIIHMTE 150
L + Q HTG Y+C LA + K ++ +F+S T + S+ PE + +
Sbjct: 2535 LQITNVQVPHTGRYTC--LASSPAGHKSRSFSLNVFVSPT---IAGVGSDGNPEDVTVIL 2589
Query: 151 GRELVIPCRVTS-PNITVTLKK--FPLDT-----LIPDGKRIIWDSRKGFIISNATYKEI 202
+ C S P T+T K PL++ ++P G+ + I NA
Sbjct: 2590 NSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQ--------ILNAQEDNA 2641
Query: 203 GLLTCEATVN-GHLYKTNYLTHRQTNTIIDVQIS---------TPRPVKLLRGHTLVLNC 252
G +C AT G + K H + I I+ +P+ VK+ +TL L C
Sbjct: 2642 GRYSCVATNEAGEMIK-----HYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLEC 2696
Query: 253 TATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYS--VLTIDKMQNKDKGLYT 310
A + ++W Y D + + S+ H NI + L I + Q D G YT
Sbjct: 2697 EAYAIPSA--SLSW-YKDGQPLK---------SDDHVNIAANGHTLQIKEAQISDTGRYT 2744
Query: 311 CRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLET--------VAGKRSYRLSMKVKAF 362
C + ++ V+I +L+T V L + A
Sbjct: 2745 CVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAA 2804
Query: 363 PSPEVVWLKDGLPATEK-SARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTAT 421
P P + W KDG P T L G L I EDAG YT + +
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVR 2864
Query: 422 LIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
++V P I + A S P+ + ++ C + G P P W
Sbjct: 2865 VLV---PPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSW 2906
Score = 57.8 bits (138), Expect = 3e-08
Identities = 51/191 (26%), Positives = 78/191 (40%), Gaps = 13/191 (6%)
Query: 281 RIDQSNSHANIFYS--VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKH 338
R+ ++H I +L I K + D G Y CR + N +++Y I
Sbjct: 3098 RMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPE 3157
Query: 339 RKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSA---RYLTRGYSLIIKDV 395
R + ++ET++ + L+ P P + WLK+ + R L+ G L I
Sbjct: 3158 R-EVIVETISNPVT--LTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARS 3214
Query: 396 TEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCT 455
D+GNYT + S + K L + V P + A + P LG L C
Sbjct: 3215 QHSDSGNYTCIASNMEGKAQKYYF--LSIQVPPSV---AGAEIPSDVSVLLGENVELVCN 3269
Query: 456 AYGIPQPTIKW 466
A GIP P I+W
Sbjct: 3270 ANGIPTPLIQW 3280
Score = 57.8 bits (138), Expect = 3e-08
Identities = 72/289 (24%), Positives = 112/289 (38%), Gaps = 30/289 (10%)
Query: 180 DGKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRP 239
DG RI+ S I G TC A + H +I Q P
Sbjct: 3942 DGYRIL--SSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQ---PSE 3996
Query: 240 VKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTID 299
+ ++ + ++L C AT + + TW + N S R +HA + L I
Sbjct: 3997 LHVILNNPILLPCEATGTPSPFI--TWQ-KEGINVNTSGR-------NHAVLPSGGLQIS 4046
Query: 300 KMQNKDKGLYTCRVRS--GPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSM 357
+ +D G Y C ++ G + + +V + + H K+ V +A + LS
Sbjct: 4047 RAVREDAGTYMCVAQNPAGTALGKIKLNVQVPP---VISPHLKEYV---IAVDKPITLSC 4100
Query: 358 KVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKN 417
+ P P++ W KDG E + + SL I V DAG+YT + + + +
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGS--SS 4158
Query: 418 LTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+ L V+V P+I S S+ IL C A GIP P I W
Sbjct: 4159 TSTKLTVHVPPRI-----RSTEGHYTVNENSQAILPCVADGIPTPAINW 4202
Score = 57.4 bits (137), Expect = 3e-08
Identities = 85/388 (21%), Positives = 145/388 (37%), Gaps = 38/388 (9%)
Query: 92 LTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEG 151
L L + TG Y C + V K+ + +++ S G PE I + E
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN------HRSPENISVVEK 2401
Query: 152 RELVIPCRVTS---PNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCE 208
+ + C + P+IT +P+ + + RI+ R + T ++ G TC
Sbjct: 2402 NSVSLTCEASGIPLPSITWFKDGWPVS--LSNSVRILSGGRM-LRLMQTTMEDAGQYTCV 2458
Query: 209 A-TVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWS 267
G K L+ I+ +T VK+ ++ L C T N ++TW
Sbjct: 2459 VRNAAGEERKIFGLSVLVPPHIVGE--NTLEDVKVKEKQSVTLTCEVTG--NPVPEITWH 2514
Query: 268 YPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVH 327
+ + I L I +Q G YTC S KS + S++
Sbjct: 2515 KDGQPLQEDEAHHIISGGR--------FLQITNVQVPHTGRYTCLASSPAGHKSRSFSLN 2566
Query: 328 IYDKAFIT-VKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPA-TEKSARYLT 385
++ I V TV L + ++P + W KDG P + ++ R L
Sbjct: 2567 VFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILP 2626
Query: 386 RGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYP 445
G +L I + E++AG Y+ + + + + K+ + + P I K P L P
Sbjct: 2627 GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYI---PPIINKG--DLWGPGLSP 2681
Query: 446 ------LGSRQILTCTAYGIPQPTIKWF 467
+ + L C AY IP ++ W+
Sbjct: 2682 KEVKIKVNNTLTLECEAYAIPSASLSWY 2709
Score = 57.0 bits (136), Expect = 4e-08
Identities = 88/389 (22%), Positives = 139/389 (35%), Gaps = 55/389 (14%)
Query: 92 LTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEG 151
L + AQ ++TG Y C KKE E +++ P S + E + + +
Sbjct: 1790 LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHV-------PPTIKSSGLSERV-VVKY 1841
Query: 152 RELVIPCRVTS-PNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEAT 210
+ + + C PN ++T K G I S + I+ ++ G TC AT
Sbjct: 1842 KPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVAT 1901
Query: 211 VNGHLYKTNYLTHRQTNTIIDVQISTPRPV----KLLRGHTLVLN-----CTATTPLNTR 261
+T I + + P + K+L LV N C A N
Sbjct: 1902 NAAG----------ETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAG--NPV 1949
Query: 262 VQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKS 321
+TW Y D + S ++ I+ Q D G+Y C +
Sbjct: 1950 PVITW-YKDNRLLSGSTSMTFLNRGQ-------IIDIESAQISDAGIYKCVAINSAGATE 2001
Query: 322 VNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKS- 380
+ S+ ++ I+ + + V RL + + P+P + WLKDG P + S
Sbjct: 2002 LFYSLQVHVAPSISGSNN----MVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN 2057
Query: 381 -ARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIY--EKAVSS 437
+ L+ G L + D G YT + K L V V P I E+ VS
Sbjct: 2058 GLQVLSGGRILALTSAQISDTGRYTCVAVNAAGE--KQRDIDLRVYVPPNIMGEEQNVSV 2115
Query: 438 FPDPALYPLGSRQILTCTAYGIPQPTIKW 466
A+ L C + IP PT+ W
Sbjct: 2116 LISQAVE-------LLCQSDAIPPPTLTW 2137
Score = 56.6 bits (135), Expect = 6e-08
Identities = 92/435 (21%), Positives = 164/435 (37%), Gaps = 45/435 (10%)
Query: 43 MQAGQTLHLQCR----GEAAHKWSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQ 98
M+ G + L C E KW + + S S++ + R G F L
Sbjct: 804 MEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLW----- 858
Query: 99 ANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPC 158
A+ G Y C+ ++ + +S + ++ P + + P + ++ EG++L +PC
Sbjct: 859 ASDKGTYICE----AENQFGKIQSETTVTVTGLVAPLIGIS---PSVANVIEGQQLTLPC 911
Query: 159 RVTSPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEAT-VNGHLYK 217
+ + N + ++ I S I ++ G TC A+ V G K
Sbjct: 912 TLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNK 971
Query: 218 TNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRAS 277
T + TI Q + + + G + L C A+ N + + WS E +S
Sbjct: 972 TTSVVVHVLPTIQHGQ----QILSTIEGIPVTLPCKASG--NPKPSVIWSKKGELISTSS 1025
Query: 278 VRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRV--RSGPSFKSVNTSVHIYDKAFIT 335
+ S L + ++ G Y C +G + + V +V++ + F
Sbjct: 1026 AKFSAGADGS--------LYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGD 1077
Query: 336 VKHRKQQ--VLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSAR--YLTRGYSLI 391
+ Q V +V L +VK+ P P + W K+ + S R +L G S+
Sbjct: 1078 QRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG-SMK 1136
Query: 392 IKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQI 451
I + D+G Y + +N+ N+T + +NV + P +G R
Sbjct: 1137 ITETRTSDSGMYLCV----ATNIAGNVTQAVKLNVH---VPPKIQRGPKHLKVQVGQRVD 1189
Query: 452 LTCTAYGIPQPTIKW 466
+ C A G P P I W
Sbjct: 1190 IPCNAQGTPLPVITW 1204
Score = 56.6 bits (135), Expect = 6e-08
Identities = 87/407 (21%), Positives = 168/407 (41%), Gaps = 44/407 (10%)
Query: 66 MVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIY 125
+ S E+ER+ ++ + STL + A + TG Y+C +A + +++ +
Sbjct: 3287 IASGETERIRVSANG---------STLNIYGALTSDTGKYTC--VATNPAGEEDRIFNLN 3335
Query: 126 IFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVT-SPNITVTLKKFPLDTLIPDGKRI 184
++++ T R + ++ ++ + + I CR T +P + K L + R+
Sbjct: 3336 VYVTPTIRGNKDEAEKLMTLVDTS----INIECRATGTPPPQINWLKNGLPLPLSSHIRL 3391
Query: 185 IWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLR 244
+ + I+ A ++ + TC A+ + +Y +D + T + +L+
Sbjct: 3392 LAAGQVIRIV-RAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEE-ITVLK 3449
Query: 245 GHTLVLNC-TATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQN 303
G + + C T TP + + P + +V ++H VL + K +
Sbjct: 3450 GSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV-------STHG----MVLQLLKAET 3498
Query: 304 KDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFP 363
+D G YTC + S + + + + I +++ +V L+ P
Sbjct: 3499 EDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEI--SVIVNNPLELTCIASGIP 3556
Query: 364 SPEVVWLKDG--LPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTAT 421
+P++ W+KDG LP T++ + L G L I ED G YT L S + K
Sbjct: 3557 APKMTWMKDGRPLPQTDQ-VQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVR 3615
Query: 422 LIVNVKPQIYEKAVSSFPDPA-LYPLGSRQI-LTCTAYGIPQPTIKW 466
V+V P I + +P + L +RQ+ L C + +P P I W
Sbjct: 3616 --VHVPPNI-----AGTDEPRDITVLRNRQVTLECKSDAVPPPVITW 3655
Score = 56.2 bits (134), Expect = 7e-08
Identities = 88/391 (22%), Positives = 149/391 (38%), Gaps = 60/391 (15%)
Query: 92 LTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEG 151
L ++TAQ TG Y+C + KE +++ + G ++ P I +
Sbjct: 3584 LRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAG-------TDEPRDITVLRN 3636
Query: 152 RELVIPCRVTSPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEATV 211
R++ + C+ + P+ T + +G+R+ R I+S Y +I T
Sbjct: 3637 RQVTLECKSDAVPP-------PVITWLRNGERLQATPRVR-ILSGGRYLQINNADLGDTA 3688
Query: 212 NGHLYKTNYLTHRQTNTIIDVQIST-----PRPVKLLRGHTLVLNCTATTPLNTRVQMTW 266
N +N I+ V + P+ + +L + VL C A R+ TW
Sbjct: 3689 NYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRI--TW 3746
Query: 267 SYPDEKNKRASVRRRIDQSNSHANIFYSVLT-----IDKMQNKDKGLYTCRVRS--GPSF 319
K +V + +HA YS+L I D G Y C + G
Sbjct: 3747 ------RKDGAVL-----AGNHAR--YSILENGFLHIQSAHVTDTGRYLCMATNAAGTDR 3793
Query: 320 KSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDG----LP 375
+ ++ VH+ I V+ V L+ + P P + W K+G +
Sbjct: 3794 RRIDLQVHVPPS--IAPGPTNMTVIVNV----QTTLACEATGIPKPSINWRKNGHLLNVD 3847
Query: 376 ATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAV 435
+ S R L+ G SL+I + +D Y ++ + T L V V P I ++
Sbjct: 3848 QNQNSYRLLSSG-SLVIISPSVDDTATYECTVTNGAGD--DKRTVDLTVQVPPSIADE-- 3902
Query: 436 SSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
P L + ++TCTA G+P P+I W
Sbjct: 3903 ---PTDFLVTKHAPAVITCTASGVPFPSIHW 3930
Score = 55.1 bits (131), Expect = 2e-07
Identities = 87/385 (22%), Positives = 142/385 (36%), Gaps = 40/385 (10%)
Query: 92 LTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEG 151
L + A+ + TG Y C+ + V K +Y+ S G E+I T
Sbjct: 3115 LHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPE--------REVIVETIS 3166
Query: 152 RELVIPCRVTS-PNITVTLKKFPLDTLIPDGKRI-IWDSRKGFIISNATYKEIGLLTCEA 209
+ + C T P T+ K D + I I+ + + + G TC A
Sbjct: 3167 NPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIA 3226
Query: 210 T-VNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTAT---TPLNTRVQMT 265
+ + G K +L+ + ++ +I P V +L G + L C A TPL +
Sbjct: 3227 SNMEGKAQKYYFLSIQVPPSVAGAEI--PSDVSVLLGENVELVCNANGIPTPL-----IQ 3279
Query: 266 WSYPDEKNKRASVRR-RIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNT 324
W + R R+ + S NI Y LT D G YTC + +
Sbjct: 3280 WLKDGKPIASGETERIRVSANGSTLNI-YGALT------SDTGKYTCVATNPAGEEDRIF 3332
Query: 325 SVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKS-ARY 383
++++Y I + + L T+ S + + P P++ WLK+GLP S R
Sbjct: 3333 NLNVYVTPTIRGNKDEAEKLMTLVDT-SINIECRATGTPPPQINWLKNGLPLPLSSHIRL 3391
Query: 384 LTRGYSLIIKDVTEEDAGNYTILLSIKQ--SNVFKNLTATLIVNVKPQIYEKAVSSFPDP 441
L G + I D YT + S + N NL N+ + + ++
Sbjct: 3392 LAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLK-- 3449
Query: 442 ALYPLGSRQILTCTAYGIPQPTIKW 466
GS + C G P P++ W
Sbjct: 3450 -----GSSTSMACITDGTPAPSMAW 3469
Score = 53.1 bits (126), Expect = 6e-07
Identities = 74/366 (20%), Positives = 129/366 (35%), Gaps = 36/366 (9%)
Query: 103 GFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTS 162
GFY C ++ + + +T D P ++P + +T G V+ C + S
Sbjct: 495 GFYECIAVSSAGTGRAQT-------FFDVSEP--PPVIQVPNNVTVTPGERAVLTCLIIS 545
Query: 163 P-NITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYL 221
+ +T ++ D + + RI + + + + + G C + G +
Sbjct: 546 AVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVF 605
Query: 222 THRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRR 281
Q + V P+ G + + C+AT YP K
Sbjct: 606 LTVQEPPKVTVM---PKNQSFTGGSEVSIMCSAT-----------GYPKPKIAWTVNDMF 651
Query: 282 IDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQ 341
I S+ + L I KD G+Y C + N+++ + + V Q
Sbjct: 652 IVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVV---Q 708
Query: 342 QVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLI-IKDVTEEDA 400
L G + + K P P+V W K L + + L+ I++ + DA
Sbjct: 709 SELLVALGDITV-MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDA 767
Query: 401 GNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIP 460
G+YT + + +T L V P ++ P +GS L C G P
Sbjct: 768 GDYTCVAINEAGRATGKIT--LDVGSPPVFIQE-----PADVSMEIGSNVTLPCYVQGYP 820
Query: 461 QPTIKW 466
+PTIKW
Sbjct: 821 EPTIKW 826
Score = 52.4 bits (124), Expect = 1e-06
Identities = 94/398 (23%), Positives = 144/398 (36%), Gaps = 56/398 (14%)
Query: 84 NGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIP 143
NGK L L A G YSCK + + + +K F D P + + P
Sbjct: 1412 NGK----ILKLFRATPEDAGRYSCKAINIAGTSQK-------YFNIDVLVPPTIIGTNFP 1460
Query: 144 EIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPDGKRI--------IWDSRKGFIIS 195
+ + R++ + C+V FP DGK + + D + +
Sbjct: 1461 NEVSVVLNRDVALECQVKGT-------PFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLK 1513
Query: 196 NATYKEIGLLTCEAT-VNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNC-T 253
NA + G C + G K LT +I ++T + +L + L C T
Sbjct: 1514 NARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTD--ISVLINSLIKLECET 1571
Query: 254 ATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRV 313
P+ +TW + +S ID+ L I + Q D YTC V
Sbjct: 1572 RGLPMPA---ITWYKDGQPIMSSSQALYIDKGQ--------YLHIPRAQVSDSATYTCHV 1620
Query: 314 RS--GPSFKSVNTSVHIYD--KAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVW 369
+ G + KS + V++ + + KQ V+ S L K PSP + W
Sbjct: 1621 ANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIA-----HSLTLECKAAGNPSPILTW 1675
Query: 370 LKDGLPA-TEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKP 428
LKDG+P + R G L I E D G Y + + K + + V V P
Sbjct: 1676 LKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGE--KEIKYEVDVLVPP 1733
Query: 429 QIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
I +S+ + + + L C G P PTI W
Sbjct: 1734 AIEGGDETSY---FIVMVNNLLELDCHVTGSPPPTIMW 1768
Score = 51.6 bits (122), Expect = 2e-06
Identities = 88/411 (21%), Positives = 144/411 (35%), Gaps = 89/411 (21%)
Query: 91 TLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTE 150
+L + Q G Y+C V + K T +++ P ++ +I I E
Sbjct: 944 SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVL------PTIQHGQQILSTI---E 994
Query: 151 GRELVIPCRVT-SPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYK--------- 200
G + +PC+ + +P +V IW S+KG +IS ++ K
Sbjct: 995 GIPVTLPCKASGNPKPSV-----------------IW-SKKGELISTSSAKFSAGADGSL 1036
Query: 201 --------EIGLLTCEATVNGHLYK-----TNYLTHRQTNTIIDVQISTPRPVKLLRGHT 247
E G C AT K T Y+ R + P + +L G
Sbjct: 1037 YVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEE 1096
Query: 248 LVLNCTATT---PLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNK 304
+ L C + P+ +TW+ + S R S S + I + +
Sbjct: 1097 VTLPCEVKSLPPPI-----ITWAKETQLISPFSPRHTFLPSGS--------MKITETRTS 1143
Query: 305 DKGLYTCRVRS--GPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAF 362
D G+Y C + G ++V +VH+ K KH K QV + V + +
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVD------IPCNAQGT 1197
Query: 363 PSPEVVWLKDGLPATEKSARYLTR-GYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTAT 421
P P + W K G +++ +L I T DAG YT + + N+ T
Sbjct: 1198 PLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVAT--------NIAGT 1249
Query: 422 LIVNVKPQIYEKAVSSFPDPALYPLGSRQILT------CTAYGIPQPTIKW 466
+ + E +P ++ C A G P+PTIKW
Sbjct: 1250 DETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKW 1300
Score = 50.1 bits (118), Expect = 5e-06
Identities = 46/177 (25%), Positives = 74/177 (41%), Gaps = 13/177 (7%)
Query: 295 VLTIDKMQNKDKGLYTCRVRS--GPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRS 352
+L + + +D G Y+C+ + G S K N V + T + V+ R
Sbjct: 1415 ILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLN----RD 1470
Query: 353 YRLSMKVKAFPSPEVVWLKDGLP--ATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIK 410
L +VK P P++ W KDG P + + L RG L +K+ D G Y +S
Sbjct: 1471 VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNA 1530
Query: 411 QSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
K++ T + + P I K + D ++ + S L C G+P P I W+
Sbjct: 1531 AGKQAKDIKLT--IYIPPSI--KGGNVTTDISVL-INSLIKLECETRGLPMPAITWY 1582
Score = 50.1 bits (118), Expect = 5e-06
Identities = 48/178 (26%), Positives = 73/178 (41%), Gaps = 19/178 (10%)
Query: 296 LTIDKMQNKDKGLYTCRV--RSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSY 353
L I + + D G YTC ++G S K + +V++ ++K + L V +
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPP----SIKDHDSESLSVVNVREGT 3075
Query: 354 RLSMKVK--AFPSPEVVWLKDGLPATEKS-ARYLTRGYSLIIKDVTEEDAGNYTILLSIK 410
+S++ + A P P + W K+G TE + L G L IK D G Y
Sbjct: 3076 SVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINV 3135
Query: 411 QSNVFKNLTATLIV--NVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
KN + V +++ E V + +P LTC A GIP PTI W
Sbjct: 3136 AGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVT--------LTCDATGIPPPTIAW 3185
Score = 45.4 bits (106), Expect = 1e-04
Identities = 98/452 (21%), Positives = 171/452 (37%), Gaps = 50/452 (11%)
Query: 32 PELSLKGTQHIMQAGQTLHLQCRG----EAAHKWSLPEMVSKESERLSITKSACGRNGKQ 87
P LS K + ++ TL L+C A+ W K + ++I +
Sbjct: 2677 PGLSPKEVK--IKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANG------- 2727
Query: 88 FCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIH 147
TL + AQ + TG Y+C +A + + E + + I + + + E+ + + +
Sbjct: 2728 --HTLQIKEAQISDTGRYTC--VASNIAGEDELDFDVNIQVPPSFQKLWEIGNML-DTGR 2782
Query: 148 MTEGRELVIPCRVT-------SPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYK 200
E ++++I ++ +P T+T K L K +I + I A +
Sbjct: 2783 NGEAKDVIINNPISLYCETNAAPPPTLTWYKDG-HPLTSSDKVLILPGGRVLQIPRAKVE 2841
Query: 201 EIGLLTCEATVNGHLYKTNYLTHRQTNTIID-VQISTPRPVKLLRGHTLVLNCTATTPLN 259
+ G TC A Y II P V +L + ++ C ++
Sbjct: 2842 DAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSS---- 2897
Query: 260 TRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYS-VLTIDKMQNKDKGLYTCRVRS--G 316
P +N + + + + H + +L I Q D G Y C + G
Sbjct: 2898 -------GSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAG 2950
Query: 317 PSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLP- 375
+ K N +VH+ +V K + L TV L+ +V FP P++ WLK+ P
Sbjct: 2951 SAKKYFNLNVHVPP----SVIGPKSENL-TVVVNNFISLTCEVSGFPPPDLSWLKNEQPI 3005
Query: 376 ATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAV 435
+ + G +L I D G YT ++I Q+ K +L V V P I +
Sbjct: 3006 KLNTNTLIVPGGRTLQIIRAKVSDGGEYT-CIAINQAGESKK-KFSLTVYVPPSIKDHDS 3063
Query: 436 SSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
S + G+ L C + +P P I W+
Sbjct: 3064 ESLSVVNVRE-GTSVSLECESNAVPPPVITWY 3094
Score = 42.7 bits (99), Expect = 8e-04
Identities = 47/177 (26%), Positives = 72/177 (40%), Gaps = 16/177 (9%)
Query: 296 LTIDKMQNKDKGLYTCRVRS--GPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGK-RS 352
L I + Q + GLY C + G K +VH+ T+K + E V K +
Sbjct: 1790 LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP----TIK--SSGLSERVVVKYKP 1843
Query: 353 YRLSMKVKAFPSPEVVWLKDGLPAT--EKSARYLTRGYSLIIKDVTEEDAGNYTILLSIK 410
L P+P + WLKD P + + + + G L I EDAG YT + +
Sbjct: 1844 VALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNA 1903
Query: 411 QSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
+++ L V+ P + E A + L + + L C A G P P I W+
Sbjct: 1904 AGETQQHIQ--LHVHEPPSL-EDAGKMLNETVL--VSNPVQLECKAAGNPVPVITWY 1955
Score = 35.4 bits (80), Expect = 0.13
Identities = 48/205 (23%), Positives = 75/205 (36%), Gaps = 29/205 (14%)
Query: 282 IDQS-NSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSF--KSVNTSVHIYDKA------ 332
+DQ+ NS+ + L I D Y C V +G ++V+ +V +
Sbjct: 3846 VDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTD 3905
Query: 333 FITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLII 392
F+ KH + T +G P P + W K+G+ + Y I
Sbjct: 3906 FLVTKHAPAVITCTASG------------VPFPSIHWTKNGIRLLPRGDGYRILSSGAIE 3953
Query: 393 KDVTE-EDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQI 451
T+ AG YT + + +++T L V+ P I + P L + +
Sbjct: 3954 ILATQLNHAGRYTCVARNAAGSAHRHVT--LHVHEPPVIQPQ-----PSELHVILNNPIL 4006
Query: 452 LTCTAYGIPQPTIKWFWHPCNHNHS 476
L C A G P P I W N N S
Sbjct: 4007 LPCEATGTPSPFITWQKEGINVNTS 4031
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 72.8 bits (177), Expect = 8e-13
Identities = 84/324 (25%), Positives = 126/324 (38%), Gaps = 37/324 (11%)
Query: 149 TEGRELVIPCRVT-SPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTC 207
TEG +PC+ SP +T K +GK I S + ++ N ++ G TC
Sbjct: 2768 TEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE-LLVKNLEGQDAGTYTC 2826
Query: 208 EA-TVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTW 266
A G + +LT ++ V + P L G L L C A R+ T
Sbjct: 2827 TAENAVGRARRRVHLTI----LVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWT- 2881
Query: 267 SYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSV 326
N R +Q S L + +D G Y C + + V
Sbjct: 2882 -----VNDRPVTEGVSEQDGG------STLQRAAVSREDSGTYVCWAENRVGRTQAVSFV 2930
Query: 327 HIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTR 386
H+ + A + ++E V G S +L V+ P P++ W+KDGLP R+ +
Sbjct: 2931 HVKE-APVLQGEAFSYLVEPVGG--SIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQ 2987
Query: 387 GYSLIIKDVTEEDAGNYTIL----LSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPA 442
SL I+ +DAG Y L + + + V L + + V+PQ + V S D A
Sbjct: 2988 NGSLTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQ--DMTVRSGDDVA 3045
Query: 443 LYPLGSRQILTCTAYGIPQPTIKW 466
L C A G P PTI+W
Sbjct: 3046 ---------LRCQATGEPTPTIEW 3060
Score = 62.8 bits (151), Expect = 8e-10
Identities = 55/176 (31%), Positives = 73/176 (41%), Gaps = 15/176 (8%)
Query: 296 LTIDKMQNKDKGLYTCRV--RSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSY 353
L + + + D G+YTC +G K V SV + AF Q + G ++
Sbjct: 1711 LQLGRARLSDSGMYTCEALNAAGRDQKLVQLSV-LVPPAFRQAPRGPQDAVLVRVGDKAV 1769
Query: 354 RLSMKVKAFPSPEVVWLKDGLPAT-EKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQS 412
LS + A P P V W KDG P + + L G L I++ D G Y S K S
Sbjct: 1770 -LSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLY----SCKVS 1824
Query: 413 NVFKNL--TATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
NV T TL V V P + A GS +LTC G+P PT+ W
Sbjct: 1825 NVAGEAVRTFTLTVQVPPTFENPKTETVSQVA----GSPLVLTCDVSGVPAPTVTW 1876
Score = 59.3 bits (142), Expect = 9e-09
Identities = 48/172 (27%), Positives = 75/172 (43%), Gaps = 7/172 (4%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
L + + Q+ D G+YTC+ + T + +Y I + V++ VAG R L
Sbjct: 276 LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAG-RPVAL 334
Query: 356 SMKVKAFPSPEVVWLKDGLPATEKS-ARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNV 414
+ PSP + W +GLP E + +R T G L ++ E +G Y+ + S
Sbjct: 335 ECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEA 394
Query: 415 FKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
L ++ V V PQ+ V+ +G L C A G P PTI+W
Sbjct: 395 V--LQYSVEVQVPPQL---LVAEGLGQVTTIVGQPLELPCQASGSPVPTIQW 441
Score = 59.3 bits (142), Expect = 9e-09
Identities = 94/414 (22%), Positives = 160/414 (38%), Gaps = 55/414 (13%)
Query: 69 KESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFI 128
K+S+ LS+ + G TL L A+ + +G Y+C+ L +K + ++ +
Sbjct: 1691 KDSQALSLGEEVFLLPGTH---TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLV-- 1745
Query: 129 SDTGRPFVEMYSEIPE-IIHMTEGRELVIPCRVTS-PNITVTLKKFPLDTLIPDGKRIIW 186
P P+ + + G + V+ C + P TVT K DG+ ++
Sbjct: 1746 ----PPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYK--------DGQPLVL 1793
Query: 187 DSRKGFI-------ISNATYKEIGLLTCEAT-VNGHLYKTNYLTHRQTNTIIDVQISTPR 238
R + I A + GL +C+ + V G +T LT + T + + T
Sbjct: 1794 AQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTET-- 1851
Query: 239 PVKLLRGHTLVLNCTAT-TPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLT 297
V + G LVL C + P T +TW + ++V + + L
Sbjct: 1852 -VSQVAGSPLVLTCDVSGVPAPT---VTWLKDRMPVESSAVHGVVSRGGR--------LQ 1899
Query: 298 IDKMQNKDKGLYTCRVRS--GPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
+ ++Q G YTC + + K +V + + + R+ VLE + RL
Sbjct: 1900 LSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEG----QEVRL 1955
Query: 356 SMKVKAFPSPEVVWLKDGLPATEKSA---RYLTRGYSLIIKDVTEEDAGNYTILLSIKQS 412
+ P P+V WLKDG P + R+ G SL++K + DAG YT +
Sbjct: 1956 DCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 2015
Query: 413 NVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+ T ++ V P I + A S + G + C G P + W
Sbjct: 2016 EDARLHTVNVL--VPPTIKQGADGS--GTLVSRPGELVTMVCPVRGSPPIHVSW 2065
Score = 58.5 bits (140), Expect = 1e-08
Identities = 83/398 (20%), Positives = 157/398 (39%), Gaps = 57/398 (14%)
Query: 91 TLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTE 150
+L + AQA HTG YSC +A + + E + + + + E+ ++ + ++T
Sbjct: 1031 SLHVERAQAAHTGRYSC--VAENLAGRAERKFELSVLVPP------ELIGDLDPLTNITA 1082
Query: 151 GRE--LVIPCR---VTSPNITVTLKKFPL----DTLIPDGKRIIWDSRKGFIISNATYKE 201
L + C + P I + P+ DT + G ++ ++ ++
Sbjct: 1083 ALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLK-------MTQTQEQD 1135
Query: 202 IGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTR 261
GL +C A+ + N+ I+ + +K+L G T L C T + +
Sbjct: 1136 SGLYSCLASNEAGEARRNFSVEVLVPPSIENE-DLEEVIKVLDGQTAHLMCNVTG--HPQ 1192
Query: 262 VQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRS--GPSF 319
++TW R H + +L + + G Y+C + G
Sbjct: 1193 PKLTWFKDGRPLARGDAH--------HISPDGVLLQVLQANLSSAGHYSCIAANAVGEKT 1244
Query: 320 KSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLP-ATE 378
K SV + + + + TV L + AFPSP + W+KDG P
Sbjct: 1245 KHFQLSVLLAPTILGGAEDSADEEV-TVTVNNPISLICEALAFPSPNITWMKDGAPFEAS 1303
Query: 379 KSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSF 438
++ + L + L I + +EDAG YT +++ + KN ++ + P I +
Sbjct: 1304 RNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVL--IPPSISK------ 1355
Query: 439 PDPALYPLGSRQI---------LTCTAYGIPQPTIKWF 467
D L +G +++ L C ++ +P PTI+W+
Sbjct: 1356 -DDPLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWY 1392
Score = 53.5 bits (127), Expect = 5e-07
Identities = 51/174 (29%), Positives = 68/174 (39%), Gaps = 15/174 (8%)
Query: 296 LTIDKMQNKDKGLYTCRVR--SGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSY 353
L I+K+ +D+G+YTC +G S + V K + V + V S
Sbjct: 568 LQIEKVDLRDEGIYTCAATNLAGESKREVAL------KVLVPPNIEPGPVNKAVLENASV 621
Query: 354 RLSMKVKAFPSPEVVWLKDGLPATE-KSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQS 412
L P P+V W K P + G L I+ DAG+Y + S
Sbjct: 622 TLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAG 681
Query: 413 NVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+ L L VNV P+I S P P L R LTC A G P PT+ W
Sbjct: 682 ST--ELRYGLRVNVPPRI--TLPPSLPGPVLVNTPVR--LTCNATGAPSPTLMW 729
Score = 52.8 bits (125), Expect = 8e-07
Identities = 45/171 (26%), Positives = 71/171 (41%), Gaps = 10/171 (5%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
L I K+Q D G++TC S N ++ + + + V+ V L
Sbjct: 2087 LRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVV--VVRGSLVEL 2144
Query: 356 SMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVF 415
+ + P P V W+KDG P +S L +G SL ++ V D+G Y+ + +
Sbjct: 2145 PCEARGVPLPLVSWMKDGEPLLSQS---LEQGPSLQLEAVGAGDSGTYSCVAVSEAGEAR 2201
Query: 416 KNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
++ T++ P I + S P G+ L C A G PQP I W
Sbjct: 2202 RHFQLTVME--PPHIED---SGQPTELSLTPGAPMELLCDAQGTPQPNITW 2247
Score = 52.0 bits (123), Expect = 1e-06
Identities = 86/382 (22%), Positives = 141/382 (36%), Gaps = 45/382 (11%)
Query: 91 TLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTE 150
+L L A +G YSC V S+ E + + + P +E + P + +T
Sbjct: 2175 SLQLEAVGAGDSGTYSC----VAVSEAGEARRHFQLTVMEP--PHIEDSGQ-PTELSLTP 2227
Query: 151 GRELVIPCRVT-SPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEA 209
G + + C +P +T K DG+ + ++ GL TC A
Sbjct: 2228 GAPMELLCDAQGTPQPNITWHK--------DGQALTRLENNSRATRVLRVRDAGLYTCLA 2279
Query: 210 TVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYP 269
+ ++ Q I V PR V L LVL C+ ++ TW
Sbjct: 2280 ESPAGAIEKSFRVRVQAPPNI-VGPRGPRFVVGLAPGQLVLECSVEAEPAPKI--TWH-- 2334
Query: 270 DEKNKRASVRRRIDQSNSHANIFYS--VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVH 327
R + + Q ++H L + + D G Y+C R+ SV V
Sbjct: 2335 -----RDGI---VLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVE 2386
Query: 328 IYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARY--LT 385
I+ I R V+ ++ L + P+P V W KD +P +S R+ L
Sbjct: 2387 IHTVPTI----RSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILP 2442
Query: 386 RGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYP 445
G SL I+ V +DAG+Y L S + + + + A++ P
Sbjct: 2443 EG-SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV-------LEPPAIAPSPSNLTLT 2494
Query: 446 LGSRQILTCTAYGIPQPTIKWF 467
+ +L C A G P+P + W+
Sbjct: 2495 AHTPALLPCEASGSPKPLVVWW 2516
Score = 52.0 bits (123), Expect = 1e-06
Identities = 46/165 (27%), Positives = 68/165 (41%), Gaps = 21/165 (12%)
Query: 307 GLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRK-----QQVLETVAGKRSYRLSMKVKA 361
G YTC R N++ + F+TV+ V+ VA + L +
Sbjct: 2641 GRYTCSAR--------NSAGVAHKHVFLTVQASPVVKPLPSVVRAVA-EEEVLLPCEASG 2691
Query: 362 FPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTAT 421
P P + W K+GL + + G L I + EDAGNY L I +++ + T
Sbjct: 2692 IPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNY---LCIAKNSAGSAMGKT 2748
Query: 422 LIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+V P + E + PD + GS L C A G P+P I W
Sbjct: 2749 RLVVQVPPVIE---NGLPDLSTTE-GSHAFLPCKARGSPEPNITW 2789
Score = 49.7 bits (117), Expect = 7e-06
Identities = 97/443 (21%), Positives = 163/443 (36%), Gaps = 63/443 (14%)
Query: 42 IMQAGQTLHLQCRGEAAHKWSLPEMVS---KESERLSITKSACGRNGKQFCSTLTLNTAQ 98
+++ G L C +A LPE K+ + L + + G Q L + AQ
Sbjct: 1761 LVRVGDKAVLSCETDA-----LPEPTVTWYKDGQPLVLAQRTQALRGGQ---RLEIQEAQ 1812
Query: 99 ANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPC 158
+ G YSCK V + + + P E + E + G LV+ C
Sbjct: 1813 VSDKGLYSCKVSNVAGEAVRTFTLTVQV------PPTFE--NPKTETVSQVAGSPLVLTC 1864
Query: 159 RVT---SPNITVTLKKFPLDTLIPDGKRIIWDSRKGFI-ISNATYKEIGLLTCEATVNGH 214
V+ +P +T + P+++ G SR G + +S + G TC A
Sbjct: 1865 DVSGVPAPTVTWLKDRMPVESSAVHGVV----SRGGRLQLSRLQPAQAGTYTCVAE---- 1916
Query: 215 LYKTNYLTHRQTNTIIDVQIS-------TPRPVKLLRGHTLVLNCTAT-TPLNTRVQMTW 266
N + + ++ V ++ R +L G + L+C A P +
Sbjct: 1917 ----NTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKD 1972
Query: 267 SYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSV 326
P ++ +R +D + L + ++ D G YTC V P+ + +
Sbjct: 1973 GSPLGQDMGPHLRFYLDGGS---------LVLKGLRASDAGAYTC-VAHNPAGEDAR--L 2020
Query: 327 HIYDKAFITVKHRKQQVLETVAGKRSYRLSM--KVKAFPSPEVVWLKDGLPATEKSARYL 384
H + + T+ + ++M V+ P V WLKDGLP L
Sbjct: 2021 HTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLL 2080
Query: 385 -TRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPAL 443
G++L I V DAG +T + + +N T + V P + E F + +
Sbjct: 2081 HGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQV---PPVLEPV--EFQNDVV 2135
Query: 444 YPLGSRQILTCTAYGIPQPTIKW 466
GS L C A G+P P + W
Sbjct: 2136 VVRGSLVELPCEARGVPLPLVSW 2158
Score = 47.8 bits (112), Expect = 3e-05
Identities = 50/184 (27%), Positives = 70/184 (38%), Gaps = 14/184 (7%)
Query: 288 HANIFYSVLTIDKMQNKDKGLYTCRV--RSGPSFKSVNTSVHIYDKAFITVKHRKQQVLE 345
H + ++L +D+ D G YTC ++G S K N +V + + H
Sbjct: 836 HLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTL----- 890
Query: 346 TVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSA---RYLTRGYSLIIKDVTEEDAGN 402
TV RLS + + P P++ W KDG P + A G L + G
Sbjct: 891 TVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGT 950
Query: 403 YTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQP 462
YT S N ++L L V+V PQI P L C A G P P
Sbjct: 951 YTCECSNVVGNSSQDL--QLEVHVPPQI--AGPREPPTQVSVVQDGVATLECNATGKPPP 1006
Query: 463 TIKW 466
T+ W
Sbjct: 1007 TVTW 1010
Score = 46.6 bits (109), Expect = 6e-05
Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 4/117 (3%)
Query: 352 SYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRG-YSLIIKDVTEEDAGNYTILLSIK 410
S L V A P+PEV W KD + +L G ++L + D+G YT
Sbjct: 1672 SVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNA 1731
Query: 411 QSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
K + +++V P + +A D L +G + +L+C +P+PT+ W+
Sbjct: 1732 AGRDQKLVQLSVLV---PPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWY 1785
Score = 42.7 bits (99), Expect = 8e-04
Identities = 46/175 (26%), Positives = 63/175 (36%), Gaps = 11/175 (6%)
Query: 295 VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYR 354
VL I D+G Y C S ++ + + ++ I + +V V +
Sbjct: 182 VLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEV--AVMEDHLVQ 239
Query: 355 LSMKVKAFPSPEVVWLKDG-LPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSN 413
L + + P+P + W KDG L T Y G L + DAG YT K SN
Sbjct: 240 LLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYT----CKASN 295
Query: 414 VF--KNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
L V V P I + P G L C A G P PT+ W
Sbjct: 296 AVGAAEKATRLDVYVPPTI--EGAGGRPYVVKAVAGRPVALECVARGHPSPTLSW 348
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/186 (23%), Positives = 69/186 (37%), Gaps = 16/186 (8%)
Query: 288 HANIFYSVLTIDKMQNKDKGLYTCRVRS--GPSFKSVNTSVHIYDKAFITVKHRKQQVLE 345
H + +L + + Q +G YTC + G S + + VH+ + R+
Sbjct: 930 HVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQI---AGPREPPTQV 986
Query: 346 TVAGKRSYRLSMKVKAFPSPEVVWLKDGLPA-TEKSARYLTRGYSLIIKDVTEEDAGNYT 404
+V L P P V W +DG P E + +G SL ++ G Y+
Sbjct: 987 SVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYS 1046
Query: 405 ILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALY---PLGSRQILTCTAYGIPQ 461
+ + +++V P++ DP L S L C A GIP
Sbjct: 1047 CVAENLAGRAERKFELSVLV--PPELIGDL-----DPLTNITAALHSPLTLLCEAMGIPP 1099
Query: 462 PTIKWF 467
P I+WF
Sbjct: 1100 PAIRWF 1105
Score = 42.0 bits (97), Expect = 0.001
Identities = 61/253 (24%), Positives = 102/253 (40%), Gaps = 36/253 (14%)
Query: 160 VTSPNITVTLKKFPLDTLIPDGKRIIWD-SRKGFIISNATYKEIGLLTCEATVNGHLYKT 218
V +PNIT F L+P ++++ + + A + G+ TC+A+
Sbjct: 247 VPTPNITW----FKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKAS-------- 294
Query: 219 NYLTHRQTNTIIDVQI--------STPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPD 270
N + + T +DV + P VK + G + L C A T S+
Sbjct: 295 NAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVA----RGHPSPTLSWHH 350
Query: 271 EKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSV-NTSVHIY 329
E A + + S SVL ++ GLY+C V S P+ ++V SV +
Sbjct: 351 EGLPVA------ESNESRLETDGSVLRLESPGEASSGLYSC-VASSPAGEAVLQYSVEVQ 403
Query: 330 DKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATE-KSARYLTRGY 388
+ V QV T+ G+ L + P P + WL++G PA E + ++G
Sbjct: 404 VPPQLLVAEGLGQVT-TIVGQ-PLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT 461
Query: 389 SLIIKDVTEEDAG 401
+L I V + +G
Sbjct: 462 TLHIDHVELDHSG 474
Score = 42.0 bits (97), Expect = 0.001
Identities = 42/175 (24%), Positives = 69/175 (39%), Gaps = 15/175 (8%)
Query: 295 VLTIDKMQNKDKGLYTCRVRS--GPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRS 352
VLT+ + D G Y+C S G + V VH+ +++ +V S
Sbjct: 752 VLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSIL------GEELNVSVVANES 805
Query: 353 YRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEE-DAGNYTILLSIKQ 411
L + A P P + W KDG P + +L+ +L+ D + DAG+YT +
Sbjct: 806 VALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQA 865
Query: 412 SNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+ K+ + V + E + + G L+C G+P P I W
Sbjct: 866 GHSEKHYNLNVWVAPVFPLRESHTLTVRE------GHPTRLSCECRGVPFPKISW 914
Score = 39.3 bits (90), Expect = 0.009
Identities = 37/118 (31%), Positives = 50/118 (42%), Gaps = 16/118 (13%)
Query: 296 LTIDKMQNKDKGLYTCRVRS--GPSFKSVNTSVHIYDK-------AFITVKHRKQQVLET 346
L I Q +D G YTC V + G + K+ + V I A + VK K +V T
Sbjct: 1315 LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKTKVNST 1374
Query: 347 VAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKS-ARYLTRGYSLIIKDVTEEDAGNY 403
+ L + A P P + W KDG P T S + L G L I+ D+G Y
Sbjct: 1375 LT------LECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRY 1426
Score = 38.9 bits (89), Expect = 0.012
Identities = 95/408 (23%), Positives = 140/408 (34%), Gaps = 64/408 (15%)
Query: 94 LNTAQAN--HTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEG 151
L QAN G YSC +A +K + + ++ T E ++ E + +T
Sbjct: 1219 LQVLQANLSSAGHYSC--IAANAVGEKTKHFQLSVLLAPTILGGAEDSAD--EEVTVTVN 1274
Query: 152 RELVIPCRVT---SPNITVTLKKFPLDTLIPDGKRI-IWDSRKGFIISNATYKEIGLLTC 207
+ + C SPNIT P + + I + G I NA ++ G TC
Sbjct: 1275 NPISLICEALAFPSPNITWMKDGAPFEA----SRNIQLLPGTHGLQILNAQKEDAGQYTC 1330
Query: 208 EATVNGHLYKTNYLTHRQTNTIIDVQISTPRP--------VKLLRGHTLVLNCT--ATTP 257
T NY +I IS P VK TL L C A P
Sbjct: 1331 VVTNELGEAVKNY----HVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESWAVPP 1386
Query: 258 LNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRS-- 315
R W Y D + S R ++ +L I Q D G Y C +
Sbjct: 1387 PTIR----W-YKDGQPVTPSSRLQVLGEGR-------LLQIQPTQVSDSGRYLCVATNVA 1434
Query: 316 GPSFKSVNTSVHI---------YDKAFITVKHRKQ------QVLETVAGKRSYRLSMKVK 360
G + N + + + AF + ++ + E V +Y L
Sbjct: 1435 GEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAY-LYCDTN 1493
Query: 361 AFPSPEVVWLKDGLPATE-KSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSN-VFKNL 418
A P P++ W ++ P + L G L I V E+AG Y S K SN V ++
Sbjct: 1494 AIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRY----SCKASNEVGEDW 1549
Query: 419 TATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
++ + P + + S L C A G P PTI W
Sbjct: 1550 LHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISW 1597
Score = 38.5 bits (88), Expect = 0.016
Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 10/115 (8%)
Query: 355 LSMKVKAFPSPEVVWLKDGLPAT---EKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQ 411
L + P P VVW KDG ++ A L +L++ +D+ + ++S +
Sbjct: 2501 LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEV 2560
Query: 412 SNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+ T V+V P I + + F + P+ +LTC + GIP PT+ W
Sbjct: 2561 GEAHRLYQVT--VHVPPTIADDQ-TDFTVTMMAPV----VLTCHSTGIPAPTVSW 2608
Score = 37.7 bits (86), Expect = 0.027
Identities = 40/178 (22%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 295 VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYR 354
VL I++ Q D G Y C + + + + IT+ + V R
Sbjct: 658 VLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLP---PSLPGPVLVNTPVR 714
Query: 355 LSMKVKAFPSPEVVWLKDG---LPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQ 411
L+ PSP ++WLKDG PA + G L + D+G Y+ +
Sbjct: 715 LTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAV 774
Query: 412 SNVFKNLTATLIVNVKPQIY--EKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
+++ L V++ P I E VS + ++ L C ++ +P P + W+
Sbjct: 775 GEDRQDV--VLQVHMPPSILGEELNVSVVANESV-------ALECQSHAMPPPVLSWW 823
Score = 37.7 bits (86), Expect = 0.027
Identities = 41/179 (22%), Positives = 74/179 (41%), Gaps = 17/179 (9%)
Query: 295 VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFIT---VKHRKQQVLETVAGKR 351
VL I ++ ++ G Y+C+ + V Y+ +T + ++++E V
Sbjct: 1523 VLQIPLVRAENAGRYSCKASN-----EVGEDWLHYELLVLTPPVILGDTEELVEEVTVNA 1577
Query: 352 SYRLSMKVKAF--PSPEVVWLKDGLP-ATEKSARYLTRGYSLIIKDVTEEDAGNYTILLS 408
S +S++ A P P + WL++GLP + + L G L + DA +Y +
Sbjct: 1578 SSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAE 1637
Query: 409 IKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
+ + K TL V V P+I + + L S L C + P P + W+
Sbjct: 1638 NQAGSAEK--LFTLRVQVPPRIAGLDL----EQVTAILNSSVSLPCDVHAHPNPEVTWY 1690
Score = 37.0 bits (84), Expect = 0.046
Identities = 33/132 (25%), Positives = 49/132 (37%), Gaps = 21/132 (15%)
Query: 351 RSYRLSMKVKAFPSPEVVWLKD----GLP------------ATEKSARYLTRGYSLIIKD 394
+S L FP PE+VWLKD G+P R L G SL
Sbjct: 34 QSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPR 93
Query: 395 VTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTC 454
+ E D+G Y+ + ++ L+V P + + L G+ L C
Sbjct: 94 IQEGDSGLYSCRAENQAGTAQRDF--HLLVLTPPSVLGAGAA---QEVLGLAGADVELQC 148
Query: 455 TAYGIPQPTIKW 466
G+P P ++W
Sbjct: 149 WTSGVPTPQVEW 160
Score = 37.0 bits (84), Expect = 0.046
Identities = 90/417 (21%), Positives = 144/417 (34%), Gaps = 69/417 (16%)
Query: 77 TKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFV 136
TK R G+Q L L AQ++ G Y+CK + +K T +Y+ P +
Sbjct: 265 TKVVYTRGGRQ----LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYV------PPTI 314
Query: 137 EMYSEIPEIIHMTEGRELVIPCRVTS-PNITVTLKKFPLDTLIPDGKRIIWDSRKGFIIS 195
E P ++ GR + + C P+ T++ L + R+ D +
Sbjct: 315 EGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDG-SVLRLE 373
Query: 196 NATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTAT 255
+ GL +C A+ Y Q + V + V + G L L C A+
Sbjct: 374 SPGEASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQ-VTTIVGQPLELPCQAS 432
Query: 256 -TPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRV- 313
+P+ T + P E+ V + + L ID ++ GL+ C+
Sbjct: 433 GSPVPTIQWLQNGRPAEELAGVQVASQ-----------GTTLHIDHVELDHSGLFACQAT 481
Query: 314 -RSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK------------ 360
+G + V SVH VLE G+ +
Sbjct: 482 NEAGTAGAEVEVSVH---------GEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRG 532
Query: 361 --AFPSPEVV--WLKDGLPATEKSARYLTRGYS----LIIKDVTEEDAGNYTILLSIKQS 412
A P P +V W G E + + YS L I+ V D G YT +
Sbjct: 533 WGAHPKPPLVEGWCSPGSLWGEPTG--IPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAG 590
Query: 413 NVFKNLTATLIV--NVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
+ + ++V N++P KAV + L C A G+P P + WF
Sbjct: 591 ESKREVALKVLVPPNIEPGPVNKAVLE---------NASVTLECLASGVPPPDVSWF 638
Score = 35.0 bits (79), Expect = 0.17
Identities = 42/174 (24%), Positives = 65/174 (37%), Gaps = 9/174 (5%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
L ++Q D GLY+CR + + + + + Q+VL +AG L
Sbjct: 89 LHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVL-GLAG-ADVEL 146
Query: 356 SMKVKAFPSPEVVWLKDGLPATEKSARYLTR--GYSLIIKDVTEEDAGNYTILLSIKQSN 413
P+P+V W KD P + G L I D G Y +
Sbjct: 147 QCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQ 206
Query: 414 VFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
++ L V+ P I+ + + A+ Q+L C A G+P P I WF
Sbjct: 207 QARDF--QLRVHAPPTIW--GSNETGEVAVMEDHLVQLL-CEARGVPTPNITWF 255
Score = 30.4 bits (67), Expect = 4.3
Identities = 34/137 (24%), Positives = 54/137 (39%), Gaps = 12/137 (8%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
LTI + + D G Y C + + + V+ + TV L
Sbjct: 2991 LTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDM----TVRSGDDVAL 3046
Query: 356 SMKVKAFPSPEVVWLKDGLP-ATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNV 414
+ P+P + WL+ G P + R L G SL +++V DAG Y + N+
Sbjct: 3047 RCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG-SLWLENVETGDAGTYDCV----AHNL 3101
Query: 415 FKNLTAT--LIVNVKPQ 429
+ TA L+V +PQ
Sbjct: 3102 LGSATARAFLVVRGEPQ 3118
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 71.6 bits (174), Expect = 2e-12
Identities = 84/324 (25%), Positives = 125/324 (38%), Gaps = 37/324 (11%)
Query: 149 TEGRELVIPCRVT-SPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTC 207
TEG +PC+ SP +T K +GK I S + ++ N ++ G TC
Sbjct: 2859 TEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE-LLVKNLEGQDAGTYTC 2917
Query: 208 EA-TVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTW 266
A G + +LT ++ V + P L G L L C A R+ T
Sbjct: 2918 TAENAVGRARRRVHLTI----LVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWT- 2972
Query: 267 SYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSV 326
N R +Q S L + +D G Y C + + V
Sbjct: 2973 -----VNDRPVTEGVSEQDGG------STLQRAAVSREDSGTYVCWAENRVGRTQAVSFV 3021
Query: 327 HIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTR 386
H+ + A + ++E V G S +L V+ P P++ W+KDGLP R+ +
Sbjct: 3022 HVKE-APVLQGEAFSYLVEPVGG--SIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQ 3078
Query: 387 GYSLIIKDVTEEDAGNYTIL----LSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPA 442
SL I +DAG Y L + + + V L + + V+PQ + V S D A
Sbjct: 3079 NGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQ--DMTVRSGDDVA 3136
Query: 443 LYPLGSRQILTCTAYGIPQPTIKW 466
L C A G P PTI+W
Sbjct: 3137 ---------LRCQATGEPTPTIEW 3151
Score = 62.8 bits (151), Expect = 8e-10
Identities = 55/176 (31%), Positives = 73/176 (41%), Gaps = 15/176 (8%)
Query: 296 LTIDKMQNKDKGLYTCRV--RSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSY 353
L + + + D G+YTC +G K V SV + AF Q + G ++
Sbjct: 1802 LQLGRARLSDSGMYTCEALNAAGRDQKLVQLSV-LVPPAFRQAPRGPQDAVLVRVGDKAV 1860
Query: 354 RLSMKVKAFPSPEVVWLKDGLPAT-EKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQS 412
LS + A P P V W KDG P + + L G L I++ D G Y S K S
Sbjct: 1861 -LSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLY----SCKVS 1915
Query: 413 NVFKNL--TATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
NV T TL V V P + A GS +LTC G+P PT+ W
Sbjct: 1916 NVAGEAVRTFTLTVQVPPTFENPKTETVSQVA----GSPLVLTCDVSGVPAPTVTW 1967
Score = 59.3 bits (142), Expect = 9e-09
Identities = 48/172 (27%), Positives = 75/172 (43%), Gaps = 7/172 (4%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
L + + Q+ D G+YTC+ + T + +Y I + V++ VAG R L
Sbjct: 367 LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAG-RPVAL 425
Query: 356 SMKVKAFPSPEVVWLKDGLPATEKS-ARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNV 414
+ PSP + W +GLP E + +R T G L ++ E +G Y+ + S
Sbjct: 426 ECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEA 485
Query: 415 FKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
L ++ V V PQ+ V+ +G L C A G P PTI+W
Sbjct: 486 V--LQYSVEVQVPPQL---LVAEGLGQVTTIVGQPLELPCQASGSPVPTIQW 532
Score = 59.3 bits (142), Expect = 9e-09
Identities = 94/414 (22%), Positives = 160/414 (38%), Gaps = 55/414 (13%)
Query: 69 KESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFI 128
K+S+ LS+ + G TL L A+ + +G Y+C+ L +K + ++ +
Sbjct: 1782 KDSQALSLGEEVFLLPGTH---TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLV-- 1836
Query: 129 SDTGRPFVEMYSEIPE-IIHMTEGRELVIPCRVTS-PNITVTLKKFPLDTLIPDGKRIIW 186
P P+ + + G + V+ C + P TVT K DG+ ++
Sbjct: 1837 ----PPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYK--------DGQPLVL 1884
Query: 187 DSRKGFI-------ISNATYKEIGLLTCEAT-VNGHLYKTNYLTHRQTNTIIDVQISTPR 238
R + I A + GL +C+ + V G +T LT + T + + T
Sbjct: 1885 AQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTET-- 1942
Query: 239 PVKLLRGHTLVLNCTAT-TPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLT 297
V + G LVL C + P T +TW + ++V + + L
Sbjct: 1943 -VSQVAGSPLVLTCDVSGVPAPT---VTWLKDRMPVESSAVHGVVSRGGR--------LQ 1990
Query: 298 IDKMQNKDKGLYTCRVRS--GPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
+ ++Q G YTC + + K +V + + + R+ VLE + RL
Sbjct: 1991 LSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEG----QEVRL 2046
Query: 356 SMKVKAFPSPEVVWLKDGLPATEKSA---RYLTRGYSLIIKDVTEEDAGNYTILLSIKQS 412
+ P P+V WLKDG P + R+ G SL++K + DAG YT +
Sbjct: 2047 DCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 2106
Query: 413 NVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+ T ++ V P I + A S + G + C G P + W
Sbjct: 2107 EDARLHTVNVL--VPPTIKQGADGS--GTLVSRPGELVTMVCPVRGSPPIHVSW 2156
Score = 58.2 bits (139), Expect = 2e-08
Identities = 83/398 (20%), Positives = 157/398 (39%), Gaps = 57/398 (14%)
Query: 91 TLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTE 150
+L + AQA HTG YSC +A + + E + + + + E+ ++ + ++T
Sbjct: 1122 SLHVERAQAAHTGRYSC--VAENLAGRAERKFELSVLVPP------ELIGDLDPLTNITA 1173
Query: 151 GRE--LVIPCR---VTSPNITVTLKKFPL----DTLIPDGKRIIWDSRKGFIISNATYKE 201
L + C + P I + P+ DT + G ++ ++ ++
Sbjct: 1174 ALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLK-------MTQTQEQD 1226
Query: 202 IGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTR 261
GL +C A+ + N+ I+ + +K+L G T L C T + +
Sbjct: 1227 SGLYSCLASNEAGEARRNFSVEVLVPPSIENE-DLEEVIKVLDGQTAHLMCNVTG--HPQ 1283
Query: 262 VQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRS--GPSF 319
++TW R H + +L + + G Y+C + G
Sbjct: 1284 PKLTWFKDGRPLARGDAH--------HISPDGVLLQVLQANLSSAGHYSCIAANAVGEKT 1335
Query: 320 KSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLP-ATE 378
K SV + + + + TV L + AFPSP + W+KDG P
Sbjct: 1336 KHFQLSVLLAPTILGGAEDSADEEV-TVTVNNPISLICEALAFPSPNITWMKDGAPFEAS 1394
Query: 379 KSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSF 438
++ + L + L I + +EDAG YT +++ + KN ++ + P I +
Sbjct: 1395 RNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVL--IPPSISK------ 1446
Query: 439 PDPALYPLGSRQI---------LTCTAYGIPQPTIKWF 467
D L +G +++ L C ++ +P PTI+W+
Sbjct: 1447 -DDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWY 1483
Score = 53.5 bits (127), Expect = 5e-07
Identities = 51/174 (29%), Positives = 68/174 (39%), Gaps = 15/174 (8%)
Query: 296 LTIDKMQNKDKGLYTCRVR--SGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSY 353
L I+K+ +D+G+YTC +G S + V K + V + V S
Sbjct: 659 LQIEKVDLRDEGIYTCAATNLAGESKREVAL------KVLVPPNIEPGPVNKAVLENASV 712
Query: 354 RLSMKVKAFPSPEVVWLKDGLPATE-KSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQS 412
L P P+V W K P + G L I+ DAG+Y + S
Sbjct: 713 TLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAG 772
Query: 413 NVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+ L L VNV P+I S P P L R LTC A G P PT+ W
Sbjct: 773 ST--ELRYGLRVNVPPRI--TLPPSLPGPVLVNTPVR--LTCNATGAPSPTLMW 820
Score = 52.8 bits (125), Expect = 8e-07
Identities = 45/171 (26%), Positives = 71/171 (41%), Gaps = 10/171 (5%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
L I K+Q D G++TC S N ++ + + + V+ V L
Sbjct: 2178 LRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVV--VVRGSLVEL 2235
Query: 356 SMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVF 415
+ + P P V W+KDG P +S L +G SL ++ V D+G Y+ + +
Sbjct: 2236 PCEARGVPLPLVSWMKDGEPLLSQS---LEQGPSLQLEAVGAGDSGTYSCVAVSEAGEAR 2292
Query: 416 KNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
++ T++ P I + S P G+ L C A G PQP I W
Sbjct: 2293 RHFQLTVME--PPHIED---SGQPTELSLTPGAPMELLCDAQGTPQPNITW 2338
Score = 52.0 bits (123), Expect = 1e-06
Identities = 86/382 (22%), Positives = 141/382 (36%), Gaps = 45/382 (11%)
Query: 91 TLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTE 150
+L L A +G YSC V S+ E + + + P +E + P + +T
Sbjct: 2266 SLQLEAVGAGDSGTYSC----VAVSEAGEARRHFQLTVMEP--PHIEDSGQ-PTELSLTP 2318
Query: 151 GRELVIPCRVT-SPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEA 209
G + + C +P +T K DG+ + ++ GL TC A
Sbjct: 2319 GAPMELLCDAQGTPQPNITWHK--------DGQALTRLENNSRATRVLRVRDAGLYTCLA 2370
Query: 210 TVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYP 269
+ ++ Q I V PR V L LVL C+ ++ TW
Sbjct: 2371 ESPAGAIEKSFRVRVQAPPNI-VGPRGPRFVVGLAPGQLVLECSVEAEPAPKI--TWH-- 2425
Query: 270 DEKNKRASVRRRIDQSNSHANIFYS--VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVH 327
R + + Q ++H L + + D G Y+C R+ SV V
Sbjct: 2426 -----RDGI---VLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVE 2477
Query: 328 IYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARY--LT 385
I+ I R V+ ++ L + P+P V W KD +P +S R+ L
Sbjct: 2478 IHTVPTI----RSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILP 2533
Query: 386 RGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYP 445
G SL I+ V +DAG+Y L S + + + + A++ P
Sbjct: 2534 EG-SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV-------LEPPAIAPSPSNLTLT 2585
Query: 446 LGSRQILTCTAYGIPQPTIKWF 467
+ +L C A G P+P + W+
Sbjct: 2586 AHTPALLPCEASGSPKPLVVWW 2607
Score = 52.0 bits (123), Expect = 1e-06
Identities = 46/165 (27%), Positives = 68/165 (41%), Gaps = 21/165 (12%)
Query: 307 GLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRK-----QQVLETVAGKRSYRLSMKVKA 361
G YTC R N++ + F+TV+ V+ VA + L +
Sbjct: 2732 GRYTCSAR--------NSAGVAHKHVFLTVQASPVVKPLPSVVRAVA-EEEVLLPCEASG 2782
Query: 362 FPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTAT 421
P P + W K+GL + + G L I + EDAGNY L I +++ + T
Sbjct: 2783 IPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNY---LCIAKNSAGSAMGKT 2839
Query: 422 LIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+V P + E + PD + GS L C A G P+P I W
Sbjct: 2840 RLVVQVPPVIE---NGLPDLSTTE-GSHAFLPCKARGSPEPNITW 2880
Score = 49.7 bits (117), Expect = 7e-06
Identities = 97/443 (21%), Positives = 163/443 (36%), Gaps = 63/443 (14%)
Query: 42 IMQAGQTLHLQCRGEAAHKWSLPEMVS---KESERLSITKSACGRNGKQFCSTLTLNTAQ 98
+++ G L C +A LPE K+ + L + + G Q L + AQ
Sbjct: 1852 LVRVGDKAVLSCETDA-----LPEPTVTWYKDGQPLVLAQRTQALRGGQ---RLEIQEAQ 1903
Query: 99 ANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPC 158
+ G YSCK V + + + P E + E + G LV+ C
Sbjct: 1904 VSDKGLYSCKVSNVAGEAVRTFTLTVQV------PPTFE--NPKTETVSQVAGSPLVLTC 1955
Query: 159 RVT---SPNITVTLKKFPLDTLIPDGKRIIWDSRKGFI-ISNATYKEIGLLTCEATVNGH 214
V+ +P +T + P+++ G SR G + +S + G TC A
Sbjct: 1956 DVSGVPAPTVTWLKDRMPVESSAVHGVV----SRGGRLQLSRLQPAQAGTYTCVAE---- 2007
Query: 215 LYKTNYLTHRQTNTIIDVQIS-------TPRPVKLLRGHTLVLNCTAT-TPLNTRVQMTW 266
N + + ++ V ++ R +L G + L+C A P +
Sbjct: 2008 ----NTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKD 2063
Query: 267 SYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSV 326
P ++ +R +D + L + ++ D G YTC V P+ + +
Sbjct: 2064 GSPLGQDMGPHLRFYLDGGS---------LVLKGLRASDAGAYTC-VAHNPAGEDAR--L 2111
Query: 327 HIYDKAFITVKHRKQQVLETVAGKRSYRLSM--KVKAFPSPEVVWLKDGLPATEKSARYL 384
H + + T+ + ++M V+ P V WLKDGLP L
Sbjct: 2112 HTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLL 2171
Query: 385 -TRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPAL 443
G++L I V DAG +T + + +N T + V P + E F + +
Sbjct: 2172 HGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQV---PPVLEPV--EFQNDVV 2226
Query: 444 YPLGSRQILTCTAYGIPQPTIKW 466
GS L C A G+P P + W
Sbjct: 2227 VVRGSLVELPCEARGVPLPLVSW 2249
Score = 46.6 bits (109), Expect = 6e-05
Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 4/117 (3%)
Query: 352 SYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRG-YSLIIKDVTEEDAGNYTILLSIK 410
S L V A P+PEV W KD + +L G ++L + D+G YT
Sbjct: 1763 SVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNA 1822
Query: 411 QSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
K + +++V P + +A D L +G + +L+C +P+PT+ W+
Sbjct: 1823 AGRDQKLVQLSVLV---PPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWY 1876
Score = 45.4 bits (106), Expect = 1e-04
Identities = 49/184 (26%), Positives = 69/184 (37%), Gaps = 14/184 (7%)
Query: 288 HANIFYSVLTIDKMQNKDKGLYTCRV--RSGPSFKSVNTSVHIYDKAFITVKHRKQQVLE 345
H + ++L +D+ D G YTC ++G S K N +V + + H
Sbjct: 927 HLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTL----- 981
Query: 346 TVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSA---RYLTRGYSLIIKDVTEEDAGN 402
TV LS + + P P++ W KDG P + A G L + G
Sbjct: 982 TVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGT 1041
Query: 403 YTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQP 462
YT S N ++L L V+V PQI P L C A G P P
Sbjct: 1042 YTCECSNVVGNSSQDL--QLEVHVPPQI--AGPREPPTQVSVVQDGVATLECNATGKPPP 1097
Query: 463 TIKW 466
T+ W
Sbjct: 1098 TVTW 1101
Score = 42.7 bits (99), Expect = 8e-04
Identities = 46/175 (26%), Positives = 63/175 (36%), Gaps = 11/175 (6%)
Query: 295 VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYR 354
VL I D+G Y C S ++ + + ++ I + +V V +
Sbjct: 273 VLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEV--AVMEDHLVQ 330
Query: 355 LSMKVKAFPSPEVVWLKDG-LPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSN 413
L + + P+P + W KDG L T Y G L + DAG YT K SN
Sbjct: 331 LLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYT----CKASN 386
Query: 414 VF--KNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
L V V P I + P G L C A G P PT+ W
Sbjct: 387 AVGAAEKATRLDVYVPPTI--EGAGGRPYVVKAVAGRPVALECVARGHPSPTLSW 439
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/186 (23%), Positives = 69/186 (37%), Gaps = 16/186 (8%)
Query: 288 HANIFYSVLTIDKMQNKDKGLYTCRVRS--GPSFKSVNTSVHIYDKAFITVKHRKQQVLE 345
H + +L + + Q +G YTC + G S + + VH+ + R+
Sbjct: 1021 HVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQI---AGPREPPTQV 1077
Query: 346 TVAGKRSYRLSMKVKAFPSPEVVWLKDGLPA-TEKSARYLTRGYSLIIKDVTEEDAGNYT 404
+V L P P V W +DG P E + +G SL ++ G Y+
Sbjct: 1078 SVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYS 1137
Query: 405 ILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALY---PLGSRQILTCTAYGIPQ 461
+ + +++V P++ DP L S L C A GIP
Sbjct: 1138 CVAENLAGRAERKFELSVLV--PPELIGDL-----DPLTNITAALHSPLTLLCEAMGIPP 1190
Query: 462 PTIKWF 467
P I+WF
Sbjct: 1191 PAIRWF 1196
Score = 42.0 bits (97), Expect = 0.001
Identities = 61/253 (24%), Positives = 102/253 (40%), Gaps = 36/253 (14%)
Query: 160 VTSPNITVTLKKFPLDTLIPDGKRIIWD-SRKGFIISNATYKEIGLLTCEATVNGHLYKT 218
V +PNIT F L+P ++++ + + A + G+ TC+A+
Sbjct: 338 VPTPNITW----FKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKAS-------- 385
Query: 219 NYLTHRQTNTIIDVQI--------STPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPD 270
N + + T +DV + P VK + G + L C A T S+
Sbjct: 386 NAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVA----RGHPSPTLSWHH 441
Query: 271 EKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSV-NTSVHIY 329
E A + + S SVL ++ GLY+C V S P+ ++V SV +
Sbjct: 442 EGLPVA------ESNESRLETDGSVLRLESPGEASSGLYSC-VASSPAGEAVLQYSVEVQ 494
Query: 330 DKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATE-KSARYLTRGY 388
+ V QV T+ G+ L + P P + WL++G PA E + ++G
Sbjct: 495 VPPQLLVAEGLGQVT-TIVGQ-PLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT 552
Query: 389 SLIIKDVTEEDAG 401
+L I V + +G
Sbjct: 553 TLHIDHVELDHSG 565
Score = 42.0 bits (97), Expect = 0.001
Identities = 42/175 (24%), Positives = 68/175 (38%), Gaps = 15/175 (8%)
Query: 295 VLTIDKMQNKDKGLYTCRVRS--GPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRS 352
VLT+ + D G Y+C S G + V VH+ +++ +V S
Sbjct: 843 VLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSIL------GEELNVSVVANES 896
Query: 353 YRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEE-DAGNYTILLSIKQ 411
L + A P P + W KDG P + +L+ +L+ D + DAG+YT +
Sbjct: 897 VALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQA 956
Query: 412 SNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
K+ + V + E + + G L+C G+P P I W
Sbjct: 957 GRSEKHYNLNVWVAPVFPLRESHTLTVRE------GHPTSLSCECRGVPFPKISW 1005
Score = 38.9 bits (89), Expect = 0.012
Identities = 95/408 (23%), Positives = 140/408 (34%), Gaps = 64/408 (15%)
Query: 94 LNTAQAN--HTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEG 151
L QAN G YSC +A +K + + ++ T E ++ E + +T
Sbjct: 1310 LQVLQANLSSAGHYSC--IAANAVGEKTKHFQLSVLLAPTILGGAEDSAD--EEVTVTVN 1365
Query: 152 RELVIPCRVT---SPNITVTLKKFPLDTLIPDGKRI-IWDSRKGFIISNATYKEIGLLTC 207
+ + C SPNIT P + + I + G I NA ++ G TC
Sbjct: 1366 NPISLICEALAFPSPNITWMKDGAPFEA----SRNIQLLPGTHGLQILNAQKEDAGQYTC 1421
Query: 208 EATVNGHLYKTNYLTHRQTNTIIDVQISTPRP--------VKLLRGHTLVLNCT--ATTP 257
T NY +I IS P VK TL L C A P
Sbjct: 1422 VVTNELGEAVKNY----HVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPP 1477
Query: 258 LNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRS-- 315
R W Y D + S R ++ +L I Q D G Y C +
Sbjct: 1478 PTIR----W-YKDGQPVTPSSRLQVLGEGR-------LLQIQPTQVSDSGRYLCVATNVA 1525
Query: 316 GPSFKSVNTSVHI---------YDKAFITVKHRKQ------QVLETVAGKRSYRLSMKVK 360
G + N + + + AF + ++ + E V +Y L
Sbjct: 1526 GEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAY-LYCDTN 1584
Query: 361 AFPSPEVVWLKDGLPATE-KSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSN-VFKNL 418
A P P++ W ++ P + L G L I V E+AG Y S K SN V ++
Sbjct: 1585 AIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRY----SCKASNEVGEDW 1640
Query: 419 TATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
++ + P + + S L C A G P PTI W
Sbjct: 1641 LHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISW 1688
Score = 38.5 bits (88), Expect = 0.016
Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 10/115 (8%)
Query: 355 LSMKVKAFPSPEVVWLKDGLPAT---EKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQ 411
L + P P VVW KDG ++ A L +L++ +D+ + ++S +
Sbjct: 2592 LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEV 2651
Query: 412 SNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+ T V+V P I + + F + P+ +LTC + GIP PT+ W
Sbjct: 2652 GEAHRLYQVT--VHVPPTIADDQ-TDFTVTMMAPV----VLTCHSTGIPAPTVSW 2699
Score = 37.7 bits (86), Expect = 0.027
Identities = 40/178 (22%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 295 VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYR 354
VL I++ Q D G Y C + + + + IT+ + V R
Sbjct: 749 VLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLP---PSLPGPVLVNTPVR 805
Query: 355 LSMKVKAFPSPEVVWLKDG---LPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQ 411
L+ PSP ++WLKDG PA + G L + D+G Y+ +
Sbjct: 806 LTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAV 865
Query: 412 SNVFKNLTATLIVNVKPQIY--EKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
+++ L V++ P I E VS + ++ L C ++ +P P + W+
Sbjct: 866 GEDRQDV--VLQVHMPPSILGEELNVSVVANESV-------ALECQSHAMPPPVLSWW 914
Score = 37.7 bits (86), Expect = 0.027
Identities = 41/179 (22%), Positives = 74/179 (41%), Gaps = 17/179 (9%)
Query: 295 VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFIT---VKHRKQQVLETVAGKR 351
VL I ++ ++ G Y+C+ + V Y+ +T + ++++E V
Sbjct: 1614 VLQIPLVRAENAGRYSCKASN-----EVGEDWLHYELLVLTPPVILGDTEELVEEVTVNA 1668
Query: 352 SYRLSMKVKAF--PSPEVVWLKDGLP-ATEKSARYLTRGYSLIIKDVTEEDAGNYTILLS 408
S +S++ A P P + WL++GLP + + L G L + DA +Y +
Sbjct: 1669 SSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAE 1728
Query: 409 IKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
+ + K TL V V P+I + + L S L C + P P + W+
Sbjct: 1729 NQAGSAEK--LFTLRVQVPPRIAGLDL----EQVTAILNSSVSLPCDVHAHPNPEVTWY 1781
Score = 37.0 bits (84), Expect = 0.046
Identities = 90/417 (21%), Positives = 144/417 (34%), Gaps = 69/417 (16%)
Query: 77 TKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFV 136
TK R G+Q L L AQ++ G Y+CK + +K T +Y+ P +
Sbjct: 356 TKVVYTRGGRQ----LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYV------PPTI 405
Query: 137 EMYSEIPEIIHMTEGRELVIPCRVTS-PNITVTLKKFPLDTLIPDGKRIIWDSRKGFIIS 195
E P ++ GR + + C P+ T++ L + R+ D +
Sbjct: 406 EGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDG-SVLRLE 464
Query: 196 NATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTAT 255
+ GL +C A+ Y Q + V + V + G L L C A+
Sbjct: 465 SPGEASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQ-VTTIVGQPLELPCQAS 523
Query: 256 -TPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRV- 313
+P+ T + P E+ V + + L ID ++ GL+ C+
Sbjct: 524 GSPVPTIQWLQNGRPAEELAGVQVASQ-----------GTTLHIDHVELDHSGLFACQAT 572
Query: 314 -RSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK------------ 360
+G + V SVH VLE G+ +
Sbjct: 573 NEAGTAGAEVEVSVH---------GEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRG 623
Query: 361 --AFPSPEVV--WLKDGLPATEKSARYLTRGYS----LIIKDVTEEDAGNYTILLSIKQS 412
A P P +V W G E + + YS L I+ V D G YT +
Sbjct: 624 WGAHPKPPLVEGWCSPGSLWGEPTG--IPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAG 681
Query: 413 NVFKNLTATLIV--NVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
+ + ++V N++P KAV + L C A G+P P + WF
Sbjct: 682 ESKREVALKVLVPPNIEPGPVNKAVLE---------NASVTLECLASGVPPPDVSWF 729
Score = 33.9 bits (76), Expect = 0.39
Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 2/68 (2%)
Query: 305 DKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPS 364
D G Y C+ + S + +Y I RK V +AG+ S L FP
Sbjct: 68 DSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANV-SGMAGQ-SLTLECDANGFPV 125
Query: 365 PEVVWLKD 372
PE+VWLKD
Sbjct: 126 PEIVWLKD 133
Score = 32.7 bits (73), Expect = 0.87
Identities = 31/109 (28%), Positives = 44/109 (40%), Gaps = 13/109 (11%)
Query: 363 PSPEVVWLKDGLPATEK-----SARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKN 417
P P+V W K P++E L G SL + V+ D+G+Y + + + +
Sbjct: 30 PKPQVTWRKG--PSSEPLHGQPGVAVLEEG-SLFLASVSPADSGDYECQATNEVGSTSRR 86
Query: 418 LTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
A L+V V P I E + G L C A G P P I W
Sbjct: 87 --AKLVVYVPPSIREDGRKANVSGMA---GQSLTLECDANGFPVPEIVW 130
Score = 30.8 bits (68), Expect = 3.3
Identities = 34/137 (24%), Positives = 54/137 (39%), Gaps = 12/137 (8%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
LTI + + D G Y C + + + V+ + TV L
Sbjct: 3082 LTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDM----TVRSGDDVAL 3137
Query: 356 SMKVKAFPSPEVVWLKDGLP-ATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNV 414
+ P+P + WL+ G P + R L G SL +++V DAG Y + N+
Sbjct: 3138 RCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG-SLWLENVETGDAGTYDCV----AHNL 3192
Query: 415 FKNLTAT--LIVNVKPQ 429
+ TA L+V +PQ
Sbjct: 3193 LGSATARAFLVVRGEPQ 3209
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 71.6 bits (174), Expect = 2e-12
Identities = 84/324 (25%), Positives = 125/324 (38%), Gaps = 37/324 (11%)
Query: 149 TEGRELVIPCRVT-SPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTC 207
TEG +PC+ SP +T K +GK I S + ++ N ++ G TC
Sbjct: 4050 TEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE-LLVKNLEGQDAGTYTC 4108
Query: 208 EA-TVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTW 266
A G + +LT ++ V + P L G L L C A R+ T
Sbjct: 4109 TAENAVGRARRRVHLTI----LVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWT- 4163
Query: 267 SYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSV 326
N R +Q S L + +D G Y C + + V
Sbjct: 4164 -----VNDRPVTEGVSEQDGG------STLQRAAVSREDSGTYVCWAENRVGRTQAVSFV 4212
Query: 327 HIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTR 386
H+ + A + ++E V G S +L V+ P P++ W+KDGLP R+ +
Sbjct: 4213 HVKE-APVLQGEAFSYLVEPVGG--SIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQ 4269
Query: 387 GYSLIIKDVTEEDAGNYTIL----LSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPA 442
SL I +DAG Y L + + + V L + + V+PQ + V S D A
Sbjct: 4270 NGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQ--DMTVRSGDDVA 4327
Query: 443 LYPLGSRQILTCTAYGIPQPTIKW 466
L C A G P PTI+W
Sbjct: 4328 ---------LRCQATGEPTPTIEW 4342
Score = 62.8 bits (151), Expect = 8e-10
Identities = 55/176 (31%), Positives = 73/176 (41%), Gaps = 15/176 (8%)
Query: 296 LTIDKMQNKDKGLYTCRV--RSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSY 353
L + + + D G+YTC +G K V SV + AF Q + G ++
Sbjct: 2993 LQLGRARLSDSGMYTCEALNAAGRDQKLVQLSV-LVPPAFRQAPRGPQDAVLVRVGDKAV 3051
Query: 354 RLSMKVKAFPSPEVVWLKDGLPAT-EKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQS 412
LS + A P P V W KDG P + + L G L I++ D G Y S K S
Sbjct: 3052 -LSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLY----SCKVS 3106
Query: 413 NVFKNL--TATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
NV T TL V V P + A GS +LTC G+P PT+ W
Sbjct: 3107 NVAGEAVRTFTLTVQVPPTFENPKTETVSQVA----GSPLVLTCDVSGVPAPTVTW 3158
Score = 59.3 bits (142), Expect = 9e-09
Identities = 48/172 (27%), Positives = 75/172 (43%), Gaps = 7/172 (4%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
L + + Q+ D G+YTC+ + T + +Y I + V++ VAG R L
Sbjct: 1558 LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAG-RPVAL 1616
Query: 356 SMKVKAFPSPEVVWLKDGLPATEKS-ARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNV 414
+ PSP + W +GLP E + +R T G L ++ E +G Y+ + S
Sbjct: 1617 ECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEA 1676
Query: 415 FKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
L ++ V V PQ+ V+ +G L C A G P PTI+W
Sbjct: 1677 V--LQYSVEVQVPPQL---LVAEGLGQVTTIVGQPLELPCQASGSPVPTIQW 1723
Score = 59.3 bits (142), Expect = 9e-09
Identities = 94/414 (22%), Positives = 160/414 (38%), Gaps = 55/414 (13%)
Query: 69 KESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFI 128
K+S+ LS+ + G TL L A+ + +G Y+C+ L +K + ++ +
Sbjct: 2973 KDSQALSLGEEVFLLPGTH---TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLV-- 3027
Query: 129 SDTGRPFVEMYSEIPE-IIHMTEGRELVIPCRVTS-PNITVTLKKFPLDTLIPDGKRIIW 186
P P+ + + G + V+ C + P TVT K DG+ ++
Sbjct: 3028 ----PPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYK--------DGQPLVL 3075
Query: 187 DSRKGFI-------ISNATYKEIGLLTCEAT-VNGHLYKTNYLTHRQTNTIIDVQISTPR 238
R + I A + GL +C+ + V G +T LT + T + + T
Sbjct: 3076 AQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTET-- 3133
Query: 239 PVKLLRGHTLVLNCTAT-TPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLT 297
V + G LVL C + P T +TW + ++V + + L
Sbjct: 3134 -VSQVAGSPLVLTCDVSGVPAPT---VTWLKDRMPVESSAVHGVVSRGGR--------LQ 3181
Query: 298 IDKMQNKDKGLYTCRVRS--GPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
+ ++Q G YTC + + K +V + + + R+ VLE + RL
Sbjct: 3182 LSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEG----QEVRL 3237
Query: 356 SMKVKAFPSPEVVWLKDGLPATEKSA---RYLTRGYSLIIKDVTEEDAGNYTILLSIKQS 412
+ P P+V WLKDG P + R+ G SL++K + DAG YT +
Sbjct: 3238 DCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 3297
Query: 413 NVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+ T ++ V P I + A S + G + C G P + W
Sbjct: 3298 EDARLHTVNVL--VPPTIKQGADGS--GTLVSRPGELVTMVCPVRGSPPIHVSW 3347
Score = 58.5 bits (140), Expect = 1e-08
Identities = 95/449 (21%), Positives = 164/449 (36%), Gaps = 61/449 (13%)
Query: 32 PELSLKGTQHIMQAGQTLHLQCRGEAAH----KWSLPEMVSKESERLSITKSACGRNGKQ 87
P++S+ + G + + C WS +E R+ +
Sbjct: 608 PQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQG------- 660
Query: 88 FCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIH 147
TL + G YSC+ T++ + + ++ +D P V S + ++
Sbjct: 661 ---TLIIQGVAPEDAGNYSCQ----ATNEVGTDQETVTLYYTDP--PSV---SAVNAVVL 708
Query: 148 MTEGRELVIPCRVTS-PNITVTLKKFPLDTLI-PDGKRIIWDSRKGFIISNATYKEIGLL 205
+ G E V+ C + P V + L+ ++ P+G S I A ++ G
Sbjct: 709 VAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGS-----SSGKLRIPAAQERDAGTY 763
Query: 206 TCEATVN-GHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTAT-TPLNTRVQ 263
TC A G L + ++ PR V + G + +L C AT P T
Sbjct: 764 TCRAVNELGDASAEIQLAVGHAPQLTEL----PRDVTVELGRSALLACRATGRPPPT--- 816
Query: 264 MTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVN 323
+TW D + +R + + VL + + +D+ Y C R+ F V
Sbjct: 817 VTWRRGD--GQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARN--VFGKVQ 872
Query: 324 TSVHIYDKAFITVKHRKQQV------LETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPAT 377
+ I H Q+ + + G+ + + P PE WLKDG P
Sbjct: 873 AEARL-----IVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLP 927
Query: 378 EKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSS 437
S + SL + +E AG Y+ + + + +++ L+V V P+I+ A
Sbjct: 928 PGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDV--ELVVQVPPRIHPTATHH 985
Query: 438 FPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+ G L C A G+P PTI W
Sbjct: 986 ITNE-----GVPASLPCVASGVPAPTITW 1009
Score = 58.2 bits (139), Expect = 2e-08
Identities = 83/398 (20%), Positives = 157/398 (39%), Gaps = 57/398 (14%)
Query: 91 TLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTE 150
+L + AQA HTG YSC +A + + E + + + + E+ ++ + ++T
Sbjct: 2313 SLHVERAQAAHTGRYSC--VAENLAGRAERKFELSVLVPP------ELIGDLDPLTNITA 2364
Query: 151 GRE--LVIPCR---VTSPNITVTLKKFPL----DTLIPDGKRIIWDSRKGFIISNATYKE 201
L + C + P I + P+ DT + G ++ ++ ++
Sbjct: 2365 ALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLK-------MTQTQEQD 2417
Query: 202 IGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTR 261
GL +C A+ + N+ I+ + +K+L G T L C T + +
Sbjct: 2418 SGLYSCLASNEAGEARRNFSVEVLVPPSIENE-DLEEVIKVLDGQTAHLMCNVTG--HPQ 2474
Query: 262 VQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRS--GPSF 319
++TW R H + +L + + G Y+C + G
Sbjct: 2475 PKLTWFKDGRPLARGDAH--------HISPDGVLLQVLQANLSSAGHYSCIAANAVGEKT 2526
Query: 320 KSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLP-ATE 378
K SV + + + + TV L + AFPSP + W+KDG P
Sbjct: 2527 KHFQLSVLLAPTILGGAEDSADEEV-TVTVNNPISLICEALAFPSPNITWMKDGAPFEAS 2585
Query: 379 KSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSF 438
++ + L + L I + +EDAG YT +++ + KN ++ + P I +
Sbjct: 2586 RNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVL--IPPSISK------ 2637
Query: 439 PDPALYPLGSRQI---------LTCTAYGIPQPTIKWF 467
D L +G +++ L C ++ +P PTI+W+
Sbjct: 2638 -DDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWY 2674
Score = 53.5 bits (127), Expect = 5e-07
Identities = 51/174 (29%), Positives = 68/174 (39%), Gaps = 15/174 (8%)
Query: 296 LTIDKMQNKDKGLYTCRVR--SGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSY 353
L I+K+ +D+G+YTC +G S + V K + V + V S
Sbjct: 1850 LQIEKVDLRDEGIYTCAATNLAGESKREVAL------KVLVPPNIEPGPVNKAVLENASV 1903
Query: 354 RLSMKVKAFPSPEVVWLKDGLPATE-KSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQS 412
L P P+V W K P + G L I+ DAG+Y + S
Sbjct: 1904 TLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAG 1963
Query: 413 NVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+ L L VNV P+I S P P L R LTC A G P PT+ W
Sbjct: 1964 ST--ELRYGLRVNVPPRI--TLPPSLPGPVLVNTPVR--LTCNATGAPSPTLMW 2011
Score = 52.8 bits (125), Expect = 8e-07
Identities = 45/171 (26%), Positives = 71/171 (41%), Gaps = 10/171 (5%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
L I K+Q D G++TC S N ++ + + + V+ V L
Sbjct: 3369 LRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVV--VVRGSLVEL 3426
Query: 356 SMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVF 415
+ + P P V W+KDG P +S L +G SL ++ V D+G Y+ + +
Sbjct: 3427 PCEARGVPLPLVSWMKDGEPLLSQS---LEQGPSLQLEAVGAGDSGTYSCVAVSEAGEAR 3483
Query: 416 KNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
++ T++ P I + S P G+ L C A G PQP I W
Sbjct: 3484 RHFQLTVME--PPHIED---SGQPTELSLTPGAPMELLCDAQGTPQPNITW 3529
Score = 52.4 bits (124), Expect = 1e-06
Identities = 38/163 (23%), Positives = 67/163 (41%), Gaps = 11/163 (6%)
Query: 305 DKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPS 364
D G Y C + + + + + +++ Q + V K +S +P+
Sbjct: 581 DGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVK----VSCSASGYPT 636
Query: 365 PEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIV 424
P + W ++ E S ++ +LII+ V EDAGNY+ + + T TL
Sbjct: 637 PHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGT--DQETVTLYY 694
Query: 425 NVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
P +VS+ L +G +L C A G+P P + W+
Sbjct: 695 TDPP-----SVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWY 732
Score = 52.0 bits (123), Expect = 1e-06
Identities = 86/382 (22%), Positives = 141/382 (36%), Gaps = 45/382 (11%)
Query: 91 TLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTE 150
+L L A +G YSC V S+ E + + + P +E + P + +T
Sbjct: 3457 SLQLEAVGAGDSGTYSC----VAVSEAGEARRHFQLTVMEP--PHIEDSGQ-PTELSLTP 3509
Query: 151 GRELVIPCRVT-SPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEA 209
G + + C +P +T K DG+ + ++ GL TC A
Sbjct: 3510 GAPMELLCDAQGTPQPNITWHK--------DGQALTRLENNSRATRVLRVRDAGLYTCLA 3561
Query: 210 TVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYP 269
+ ++ Q I V PR V L LVL C+ ++ TW
Sbjct: 3562 ESPAGAIEKSFRVRVQAPPNI-VGPRGPRFVVGLAPGQLVLECSVEAEPAPKI--TWH-- 3616
Query: 270 DEKNKRASVRRRIDQSNSHANIFYS--VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVH 327
R + + Q ++H L + + D G Y+C R+ SV V
Sbjct: 3617 -----RDGI---VLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVE 3668
Query: 328 IYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARY--LT 385
I+ I R V+ ++ L + P+P V W KD +P +S R+ L
Sbjct: 3669 IHTVPTI----RSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILP 3724
Query: 386 RGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYP 445
G SL I+ V +DAG+Y L S + + + + A++ P
Sbjct: 3725 EG-SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV-------LEPPAIAPSPSNLTLT 3776
Query: 446 LGSRQILTCTAYGIPQPTIKWF 467
+ +L C A G P+P + W+
Sbjct: 3777 AHTPALLPCEASGSPKPLVVWW 3798
Score = 52.0 bits (123), Expect = 1e-06
Identities = 46/165 (27%), Positives = 68/165 (41%), Gaps = 21/165 (12%)
Query: 307 GLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRK-----QQVLETVAGKRSYRLSMKVKA 361
G YTC R N++ + F+TV+ V+ VA + L +
Sbjct: 3923 GRYTCSAR--------NSAGVAHKHVFLTVQASPVVKPLPSVVRAVA-EEEVLLPCEASG 3973
Query: 362 FPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTAT 421
P P + W K+GL + + G L I + EDAGNY L I +++ + T
Sbjct: 3974 IPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNY---LCIAKNSAGSAMGKT 4030
Query: 422 LIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+V P + E + PD + GS L C A G P+P I W
Sbjct: 4031 RLVVQVPPVIE---NGLPDLSTTE-GSHAFLPCKARGSPEPNITW 4071
Score = 49.7 bits (117), Expect = 7e-06
Identities = 97/443 (21%), Positives = 163/443 (36%), Gaps = 63/443 (14%)
Query: 42 IMQAGQTLHLQCRGEAAHKWSLPEMVS---KESERLSITKSACGRNGKQFCSTLTLNTAQ 98
+++ G L C +A LPE K+ + L + + G Q L + AQ
Sbjct: 3043 LVRVGDKAVLSCETDA-----LPEPTVTWYKDGQPLVLAQRTQALRGGQ---RLEIQEAQ 3094
Query: 99 ANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPC 158
+ G YSCK V + + + P E + E + G LV+ C
Sbjct: 3095 VSDKGLYSCKVSNVAGEAVRTFTLTVQV------PPTFE--NPKTETVSQVAGSPLVLTC 3146
Query: 159 RVT---SPNITVTLKKFPLDTLIPDGKRIIWDSRKGFI-ISNATYKEIGLLTCEATVNGH 214
V+ +P +T + P+++ G SR G + +S + G TC A
Sbjct: 3147 DVSGVPAPTVTWLKDRMPVESSAVHGVV----SRGGRLQLSRLQPAQAGTYTCVAE---- 3198
Query: 215 LYKTNYLTHRQTNTIIDVQIS-------TPRPVKLLRGHTLVLNCTAT-TPLNTRVQMTW 266
N + + ++ V ++ R +L G + L+C A P +
Sbjct: 3199 ----NTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKD 3254
Query: 267 SYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSV 326
P ++ +R +D + L + ++ D G YTC V P+ + +
Sbjct: 3255 GSPLGQDMGPHLRFYLDGGS---------LVLKGLRASDAGAYTC-VAHNPAGEDAR--L 3302
Query: 327 HIYDKAFITVKHRKQQVLETVAGKRSYRLSM--KVKAFPSPEVVWLKDGLPATEKSARYL 384
H + + T+ + ++M V+ P V WLKDGLP L
Sbjct: 3303 HTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLL 3362
Query: 385 -TRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPAL 443
G++L I V DAG +T + + +N T + V P + E F + +
Sbjct: 3363 HGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQV---PPVLEPV--EFQNDVV 3417
Query: 444 YPLGSRQILTCTAYGIPQPTIKW 466
GS L C A G+P P + W
Sbjct: 3418 VVRGSLVELPCEARGVPLPLVSW 3440
Score = 46.6 bits (109), Expect = 6e-05
Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 4/117 (3%)
Query: 352 SYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRG-YSLIIKDVTEEDAGNYTILLSIK 410
S L V A P+PEV W KD + +L G ++L + D+G YT
Sbjct: 2954 SVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNA 3013
Query: 411 QSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
K + +++V P + +A D L +G + +L+C +P+PT+ W+
Sbjct: 3014 AGRDQKLVQLSVLV---PPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWY 3067
Score = 45.4 bits (106), Expect = 1e-04
Identities = 49/184 (26%), Positives = 69/184 (37%), Gaps = 14/184 (7%)
Query: 288 HANIFYSVLTIDKMQNKDKGLYTCRV--RSGPSFKSVNTSVHIYDKAFITVKHRKQQVLE 345
H + ++L +D+ D G YTC ++G S K N +V + + H
Sbjct: 2118 HLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTL----- 2172
Query: 346 TVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSA---RYLTRGYSLIIKDVTEEDAGN 402
TV LS + + P P++ W KDG P + A G L + G
Sbjct: 2173 TVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGT 2232
Query: 403 YTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQP 462
YT S N ++L L V+V PQI P L C A G P P
Sbjct: 2233 YTCECSNVVGNSSQDL--QLEVHVPPQI--AGPREPPTQVSVVQDGVATLECNATGKPPP 2288
Query: 463 TIKW 466
T+ W
Sbjct: 2289 TVTW 2292
Score = 42.7 bits (99), Expect = 8e-04
Identities = 45/178 (25%), Positives = 66/178 (37%), Gaps = 23/178 (12%)
Query: 305 DKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPS 364
D G Y C+ + S + +Y I RK V +AG+ S L FP
Sbjct: 1272 DSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANV-SGMAGQ-SLTLECDANGFPV 1329
Query: 365 PEVVWLKD----GLP------------ATEKSARYLTRGYSLIIKDVTEEDAGNYTILLS 408
PE+VWLKD G+P R L G SL + E D+G Y+
Sbjct: 1330 PEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAE 1389
Query: 409 IKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+ ++ L+V P + + L G+ L C G+P P ++W
Sbjct: 1390 NQAGTAQRDF--HLLVLTPPSVLGAGAA---QEVLGLAGADVELQCWTSGVPTPQVEW 1442
Score = 42.7 bits (99), Expect = 8e-04
Identities = 46/175 (26%), Positives = 63/175 (36%), Gaps = 11/175 (6%)
Query: 295 VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYR 354
VL I D+G Y C S ++ + + ++ I + +V V +
Sbjct: 1464 VLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEV--AVMEDHLVQ 1521
Query: 355 LSMKVKAFPSPEVVWLKDG-LPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSN 413
L + + P+P + W KDG L T Y G L + DAG YT K SN
Sbjct: 1522 LLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYT----CKASN 1577
Query: 414 VF--KNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
L V V P I + P G L C A G P PT+ W
Sbjct: 1578 AVGAAEKATRLDVYVPPTI--EGAGGRPYVVKAVAGRPVALECVARGHPSPTLSW 1630
Score = 42.4 bits (98), Expect = 0.001
Identities = 42/175 (24%), Positives = 69/175 (39%), Gaps = 15/175 (8%)
Query: 295 VLTIDKMQNKDKGLYTCRVRS--GPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRS 352
VLT+ + D G Y+C S G + V VH+ +++ +V S
Sbjct: 2034 VLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSIL------GEELNVSVVANES 2087
Query: 353 YRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEE-DAGNYTILLSIKQ 411
L + A P P + W KDG P + +L+ +L+ D + DAG+YT +
Sbjct: 2088 VALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQA 2147
Query: 412 SNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+ K+ + V + E + + G L+C G+P P I W
Sbjct: 2148 GHSEKHYNLNVWVAPVFPLRESHTLTVRE------GHPTSLSCECRGVPFPKISW 2196
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/186 (23%), Positives = 69/186 (37%), Gaps = 16/186 (8%)
Query: 288 HANIFYSVLTIDKMQNKDKGLYTCRVRS--GPSFKSVNTSVHIYDKAFITVKHRKQQVLE 345
H + +L + + Q +G YTC + G S + + VH+ + R+
Sbjct: 2212 HVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQI---AGPREPPTQV 2268
Query: 346 TVAGKRSYRLSMKVKAFPSPEVVWLKDGLPA-TEKSARYLTRGYSLIIKDVTEEDAGNYT 404
+V L P P V W +DG P E + +G SL ++ G Y+
Sbjct: 2269 SVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYS 2328
Query: 405 ILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALY---PLGSRQILTCTAYGIPQ 461
+ + +++V P++ DP L S L C A GIP
Sbjct: 2329 CVAENLAGRAERKFELSVLV--PPELIGDL-----DPLTNITAALHSPLTLLCEAMGIPP 2381
Query: 462 PTIKWF 467
P I+WF
Sbjct: 2382 PAIRWF 2387
Score = 42.0 bits (97), Expect = 0.001
Identities = 61/253 (24%), Positives = 102/253 (40%), Gaps = 36/253 (14%)
Query: 160 VTSPNITVTLKKFPLDTLIPDGKRIIWD-SRKGFIISNATYKEIGLLTCEATVNGHLYKT 218
V +PNIT F L+P ++++ + + A + G+ TC+A+
Sbjct: 1529 VPTPNITW----FKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKAS-------- 1576
Query: 219 NYLTHRQTNTIIDVQI--------STPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPD 270
N + + T +DV + P VK + G + L C A T S+
Sbjct: 1577 NAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVA----RGHPSPTLSWHH 1632
Query: 271 EKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSV-NTSVHIY 329
E A + + S SVL ++ GLY+C V S P+ ++V SV +
Sbjct: 1633 EGLPVA------ESNESRLETDGSVLRLESPGEASSGLYSC-VASSPAGEAVLQYSVEVQ 1685
Query: 330 DKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATE-KSARYLTRGY 388
+ V QV T+ G+ L + P P + WL++G PA E + ++G
Sbjct: 1686 VPPQLLVAEGLGQVT-TIVGQ-PLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT 1743
Query: 389 SLIIKDVTEEDAG 401
+L I V + +G
Sbjct: 1744 TLHIDHVELDHSG 1756
Score = 38.9 bits (89), Expect = 0.012
Identities = 95/408 (23%), Positives = 140/408 (34%), Gaps = 64/408 (15%)
Query: 94 LNTAQAN--HTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEG 151
L QAN G YSC +A +K + + ++ T E ++ E + +T
Sbjct: 2501 LQVLQANLSSAGHYSC--IAANAVGEKTKHFQLSVLLAPTILGGAEDSAD--EEVTVTVN 2556
Query: 152 RELVIPCRVT---SPNITVTLKKFPLDTLIPDGKRI-IWDSRKGFIISNATYKEIGLLTC 207
+ + C SPNIT P + + I + G I NA ++ G TC
Sbjct: 2557 NPISLICEALAFPSPNITWMKDGAPFEA----SRNIQLLPGTHGLQILNAQKEDAGQYTC 2612
Query: 208 EATVNGHLYKTNYLTHRQTNTIIDVQISTPRP--------VKLLRGHTLVLNCT--ATTP 257
T NY +I IS P VK TL L C A P
Sbjct: 2613 VVTNELGEAVKNY----HVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPP 2668
Query: 258 LNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRS-- 315
R W Y D + S R ++ +L I Q D G Y C +
Sbjct: 2669 PTIR----W-YKDGQPVTPSSRLQVLGEGR-------LLQIQPTQVSDSGRYLCVATNVA 2716
Query: 316 GPSFKSVNTSVHI---------YDKAFITVKHRKQ------QVLETVAGKRSYRLSMKVK 360
G + N + + + AF + ++ + E V +Y L
Sbjct: 2717 GEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAY-LYCDTN 2775
Query: 361 AFPSPEVVWLKDGLPATE-KSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSN-VFKNL 418
A P P++ W ++ P + L G L I V E+AG Y S K SN V ++
Sbjct: 2776 AIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRY----SCKASNEVGEDW 2831
Query: 419 TATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
++ + P + + S L C A G P PTI W
Sbjct: 2832 LHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISW 2879
Score = 38.5 bits (88), Expect = 0.016
Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 10/115 (8%)
Query: 355 LSMKVKAFPSPEVVWLKDGLPAT---EKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQ 411
L + P P VVW KDG ++ A L +L++ +D+ + ++S +
Sbjct: 3783 LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEV 3842
Query: 412 SNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+ T V+V P I + + F + P+ +LTC + GIP PT+ W
Sbjct: 3843 GEAHRLYQVT--VHVPPTIADDQ-TDFTVTMMAPV----VLTCHSTGIPAPTVSW 3890
Score = 37.7 bits (86), Expect = 0.027
Identities = 40/178 (22%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 295 VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYR 354
VL I++ Q D G Y C + + + + IT+ + V R
Sbjct: 1940 VLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLP---PSLPGPVLVNTPVR 1996
Query: 355 LSMKVKAFPSPEVVWLKDG---LPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQ 411
L+ PSP ++WLKDG PA + G L + D+G Y+ +
Sbjct: 1997 LTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAV 2056
Query: 412 SNVFKNLTATLIVNVKPQIY--EKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
+++ L V++ P I E VS + ++ L C ++ +P P + W+
Sbjct: 2057 GEDRQDV--VLQVHMPPSILGEELNVSVVANESV-------ALECQSHAMPPPVLSWW 2105
Score = 37.7 bits (86), Expect = 0.027
Identities = 41/179 (22%), Positives = 74/179 (41%), Gaps = 17/179 (9%)
Query: 295 VLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFIT---VKHRKQQVLETVAGKR 351
VL I ++ ++ G Y+C+ + V Y+ +T + ++++E V
Sbjct: 2805 VLQIPLVRAENAGRYSCKASN-----EVGEDWLHYELLVLTPPVILGDTEELVEEVTVNA 2859
Query: 352 SYRLSMKVKAF--PSPEVVWLKDGLP-ATEKSARYLTRGYSLIIKDVTEEDAGNYTILLS 408
S +S++ A P P + WL++GLP + + L G L + DA +Y +
Sbjct: 2860 SSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAE 2919
Query: 409 IKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
+ + K TL V V P+I + + L S L C + P P + W+
Sbjct: 2920 NQAGSAEK--LFTLRVQVPPRIAGLDL----EQVTAILNSSVSLPCDVHAHPNPEVTWY 2972
Score = 37.0 bits (84), Expect = 0.046
Identities = 90/417 (21%), Positives = 144/417 (34%), Gaps = 69/417 (16%)
Query: 77 TKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFV 136
TK R G+Q L L AQ++ G Y+CK + +K T +Y+ P +
Sbjct: 1547 TKVVYTRGGRQ----LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYV------PPTI 1596
Query: 137 EMYSEIPEIIHMTEGRELVIPCRVTS-PNITVTLKKFPLDTLIPDGKRIIWDSRKGFIIS 195
E P ++ GR + + C P+ T++ L + R+ D +
Sbjct: 1597 EGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDG-SVLRLE 1655
Query: 196 NATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTAT 255
+ GL +C A+ Y Q + V + V + G L L C A+
Sbjct: 1656 SPGEASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQ-VTTIVGQPLELPCQAS 1714
Query: 256 -TPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRV- 313
+P+ T + P E+ V + + L ID ++ GL+ C+
Sbjct: 1715 GSPVPTIQWLQNGRPAEELAGVQVASQ-----------GTTLHIDHVELDHSGLFACQAT 1763
Query: 314 -RSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK------------ 360
+G + V SVH VLE G+ +
Sbjct: 1764 NEAGTAGAEVEVSVH---------GEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRG 1814
Query: 361 --AFPSPEVV--WLKDGLPATEKSARYLTRGYS----LIIKDVTEEDAGNYTILLSIKQS 412
A P P +V W G E + + YS L I+ V D G YT +
Sbjct: 1815 WGAHPKPPLVEGWCSPGSLWGEPTG--IPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAG 1872
Query: 413 NVFKNLTATLIV--NVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
+ + ++V N++P KAV + L C A G+P P + WF
Sbjct: 1873 ESKREVALKVLVPPNIEPGPVNKAVLE---------NASVTLECLASGVPPPDVSWF 1920
Score = 35.0 bits (79), Expect = 0.17
Identities = 42/174 (24%), Positives = 65/174 (37%), Gaps = 9/174 (5%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
L ++Q D GLY+CR + + + + + Q+VL +AG L
Sbjct: 1371 LHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVL-GLAG-ADVEL 1428
Query: 356 SMKVKAFPSPEVVWLKDGLPATEKSARYLTR--GYSLIIKDVTEEDAGNYTILLSIKQSN 413
P+P+V W KD P + G L I D G Y +
Sbjct: 1429 QCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQ 1488
Query: 414 VFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
++ L V+ P I+ + + A+ Q+L C A G+P P I WF
Sbjct: 1489 QARDF--QLRVHAPPTIW--GSNETGEVAVMEDHLVQLL-CEARGVPTPNITWF 1537
Score = 30.8 bits (68), Expect = 3.3
Identities = 34/137 (24%), Positives = 54/137 (39%), Gaps = 12/137 (8%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
LTI + + D G Y C + + + V+ + TV L
Sbjct: 4273 LTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDM----TVRSGDDVAL 4328
Query: 356 SMKVKAFPSPEVVWLKDGLP-ATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNV 414
+ P+P + WL+ G P + R L G SL +++V DAG Y + N+
Sbjct: 4329 RCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG-SLWLENVETGDAGTYDCV----AHNL 4383
Query: 415 FKNLTAT--LIVNVKPQ 429
+ TA L+V +PQ
Sbjct: 4384 LGSATARAFLVVRGEPQ 4400
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 68.2 bits (165), Expect = 2e-11
Identities = 85/387 (21%), Positives = 149/387 (38%), Gaps = 47/387 (12%)
Query: 95 NTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISD-TGRPFVEMYSEIPEIIHMTEGRE 153
N ++A +G Y C S + + ++ + +GR + + EG+
Sbjct: 161 NPSEAKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRT--------RSAVSVREGQG 212
Query: 154 LVIPCRVT--SPNITVT--LKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTC-- 207
+V+ C SP I + +FP + D +R I IS ++G C
Sbjct: 213 VVLMCSPPPHSPEIIYSWVFNEFP-SFVAEDSRRFISQETGNLYISKVQTSDVGSYICLV 271
Query: 208 -EATVNGH-LYKTNYLTHRQTNTIID----VQISTPRPVKLLRGHTLVLNCTAT-TPLNT 260
N L LT R + + +++ P V +G T+ + C A P+ T
Sbjct: 272 KNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPT 331
Query: 261 RVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFK 320
+TW + N + R+ +S + VL I +Q D G+Y CR +
Sbjct: 332 ---ITWM---KVNGYIPSKARLRKSQA-------VLEIPNVQLDDAGIYECRAENSRGKN 378
Query: 321 SVNTSVHIYDKAFITVKHRKQQVLETVAGKRS-YRLSMKVKAFPSPEVVWLKDGLPATEK 379
S + +Y T H +++ +T S R K P P WLK+G+P + +
Sbjct: 379 SFRGQLQVY-----TYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQ 433
Query: 380 SARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFP 439
S + G L+I +V + DAG Y L K ++ + ++ + A++
Sbjct: 434 SRVEMVNGV-LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAP----TFALNQLK 488
Query: 440 DPALYPLGSRQILTCTAYGIPQPTIKW 466
+ ++ C G P+PTI W
Sbjct: 489 KTIIVTKDQEVVIECKPQGSPKPTISW 515
Score = 38.9 bits (89), Expect = 0.012
Identities = 54/237 (22%), Positives = 95/237 (40%), Gaps = 38/237 (16%)
Query: 92 LTLNTAQANHTGFYSC----KYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIH 147
L ++ + G Y C KY A+ S + + ++ F +++ + I
Sbjct: 443 LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFA----------LNQLKKTII 492
Query: 148 MTEGRELVIPCRVT-SPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLT 206
+T+ +E+VI C+ SP T++ KK D + + KRI I NA+ + G
Sbjct: 493 VTKDQEVVIECKPQGSPKPTISWKKG--DRAVRENKRIAILPDGSLRILNASKSDEGKYV 550
Query: 207 CEA-TVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMT 265
C V G L+ ++ I TP+ +L G ++VLNC A + V
Sbjct: 551 CRGENVFGSAEIIASLSVKEPTRIE----LTPKRTELTVGESIVLNCKAIHDASLDVTFY 606
Query: 266 WS-------YPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRS 315
W+ + +E S+R + ++ L I + G Y CRV++
Sbjct: 607 WTLKGQPIDFEEEGGHFESIRAQASSAD---------LMIRNILLMHAGRYGCRVQT 654
Score = 33.9 bits (76), Expect = 0.39
Identities = 36/184 (19%), Positives = 63/184 (34%), Gaps = 12/184 (6%)
Query: 287 SHANIFYSVLTIDKMQNKDKGLYTCRVRS--GPSFKSVNTSVHIYDKAFITVKHRKQQVL 344
S + VL I + D G+Y C + G + S + F + +K +
Sbjct: 434 SRVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTII- 492
Query: 345 ETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYT 404
V + + K + P P + W K E + SL I + ++ D G Y
Sbjct: 493 --VTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYV 550
Query: 405 ILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTI 464
+ NVF + ++VK + P +G +L C A +
Sbjct: 551 ----CRGENVFGSAEIIASLSVKE---PTRIELTPKRTELTVGESIVLNCKAIHDASLDV 603
Query: 465 KWFW 468
++W
Sbjct: 604 TFYW 607
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 68.2 bits (165), Expect = 2e-11
Identities = 85/387 (21%), Positives = 149/387 (38%), Gaps = 47/387 (12%)
Query: 95 NTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISD-TGRPFVEMYSEIPEIIHMTEGRE 153
N ++A +G Y C S + + ++ + +GR + + EG+
Sbjct: 87 NPSEAKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRT--------RSAVSVREGQG 138
Query: 154 LVIPCRVT--SPNITVT--LKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTC-- 207
+V+ C SP I + +FP + D +R I IS ++G C
Sbjct: 139 VVLMCSPPPHSPEIIYSWVFNEFP-SFVAEDSRRFISQETGNLYISKVQTSDVGSYICLV 197
Query: 208 -EATVNGH-LYKTNYLTHRQTNTIID----VQISTPRPVKLLRGHTLVLNCTAT-TPLNT 260
N L LT R + + +++ P V +G T+ + C A P+ T
Sbjct: 198 KNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPT 257
Query: 261 RVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFK 320
+TW + N + R+ +S + VL I +Q D G+Y CR +
Sbjct: 258 ---ITWM---KVNGYIPSKARLRKSQA-------VLEIPNVQLDDAGIYECRAENSRGKN 304
Query: 321 SVNTSVHIYDKAFITVKHRKQQVLETVAGKRS-YRLSMKVKAFPSPEVVWLKDGLPATEK 379
S + +Y T H +++ +T S R K P P WLK+G+P + +
Sbjct: 305 SFRGQLQVY-----TYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQ 359
Query: 380 SARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFP 439
S + G L+I +V + DAG Y L K ++ + ++ + A++
Sbjct: 360 SRVEMVNGV-LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAP----TFALNQLK 414
Query: 440 DPALYPLGSRQILTCTAYGIPQPTIKW 466
+ ++ C G P+PTI W
Sbjct: 415 KTIIVTKDQEVVIECKPQGSPKPTISW 441
Score = 38.9 bits (89), Expect = 0.012
Identities = 54/237 (22%), Positives = 95/237 (40%), Gaps = 38/237 (16%)
Query: 92 LTLNTAQANHTGFYSC----KYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIH 147
L ++ + G Y C KY A+ S + + ++ F +++ + I
Sbjct: 369 LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFA----------LNQLKKTII 418
Query: 148 MTEGRELVIPCRVT-SPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLT 206
+T+ +E+VI C+ SP T++ KK D + + KRI I NA+ + G
Sbjct: 419 VTKDQEVVIECKPQGSPKPTISWKKG--DRAVRENKRIAILPDGSLRILNASKSDEGKYV 476
Query: 207 CEA-TVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMT 265
C V G L+ ++ I TP+ +L G ++VLNC A + V
Sbjct: 477 CRGENVFGSAEIIASLSVKEPTRIE----LTPKRTELTVGESIVLNCKAIHDASLDVTFY 532
Query: 266 WS-------YPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRS 315
W+ + +E S+R + ++ L I + G Y CRV++
Sbjct: 533 WTLKGQPIDFEEEGGHFESIRAQASSAD---------LMIRNILLMHAGRYGCRVQT 580
Score = 33.9 bits (76), Expect = 0.39
Identities = 36/184 (19%), Positives = 63/184 (34%), Gaps = 12/184 (6%)
Query: 287 SHANIFYSVLTIDKMQNKDKGLYTCRVRS--GPSFKSVNTSVHIYDKAFITVKHRKQQVL 344
S + VL I + D G+Y C + G + S + F + +K +
Sbjct: 360 SRVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTII- 418
Query: 345 ETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYT 404
V + + K + P P + W K E + SL I + ++ D G Y
Sbjct: 419 --VTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYV 476
Query: 405 ILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTI 464
+ NVF + ++VK + P +G +L C A +
Sbjct: 477 ----CRGENVFGSAEIIASLSVKE---PTRIELTPKRTELTVGESIVLNCKAIHDASLDV 529
Query: 465 KWFW 468
++W
Sbjct: 530 TFYW 533
>gi|27262659 colony stimulating factor 1 receptor precursor [Homo
sapiens]
Length = 972
Score = 65.5 bits (158), Expect = 1e-10
Identities = 97/459 (21%), Positives = 186/459 (40%), Gaps = 66/459 (14%)
Query: 42 IMQAGQTLHLQCRGEAAHKWSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANH 101
+++ G T+ L+C G + +W P S ++ S L+ N A +
Sbjct: 31 VVKPGATVTLRCVGNGSVEWDGPP-----SPHWTLYSDGSS-------SILSTNNATFQN 78
Query: 102 TGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVT 161
TG Y C P +AI++++ D RP+ + E+ + E ++ ++PC +T
Sbjct: 79 TGTYRCTEPGDPLGGS----AAIHLYVKDPARPWNVLAQEVV----VFEDQDALLPCLLT 130
Query: 162 SPNIT--VTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTN 219
P + V+L + L+ + GF I A + + C A + G +
Sbjct: 131 DPVLEAGVSLVRVRGRPLMRH-TNYSFSPWHGFTIHRAKFIQSQDYQCSALMGGRKVMSI 189
Query: 220 YLTHRQTNTIIDVQISTPRPVKL--LRGHTLVLNCTATTPLNTRVQMTWS-YPDEKNKRA 276
+ + I T P +L +RG + C+A++ V + + + N +
Sbjct: 190 SIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASS-----VDVNFDVFLQHNNTKL 244
Query: 277 SVRRRIDQSNSHANIFYSVLTI--DKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFI 334
++ + QS+ H N + VLT+ D++ + G Y+C + S + + + A++
Sbjct: 245 AIPQ---QSDFHNNRYQKVLTLNLDQVDFQHAGNYSCVASNVQGKHSTSMFFRVVESAYL 301
Query: 335 TVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVV-W-----LKDGLP------ATEKSAR 382
+ + + E G+ L + V+A+P + W D P AT K
Sbjct: 302 NLSSEQNLIQEVTVGE-GLNLKVMVEAYPGLQGFNWTYLGPFSDHQPEPKLANATTKDTY 360
Query: 383 YLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPA 442
T ++L + + +AG Y+ L + ++ LT L + P++ + +F
Sbjct: 361 RHT--FTLSLPRLKPSEAGRYSFLA--RNPGGWRALTFELTLRYPPEV--SVIWTF---- 410
Query: 443 LYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARCD 481
+ L C A G PQP + W C+ H++ RCD
Sbjct: 411 ---INGSGTLLCAASGYPQPNVTWL--QCS-GHTD-RCD 442
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 65.5 bits (158), Expect = 1e-10
Identities = 87/401 (21%), Positives = 151/401 (37%), Gaps = 43/401 (10%)
Query: 30 KDPELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPEMVSKESERLSITKSACGRNGKQFC 89
+ P ++ + + +G T++ CR E K PE++ + S+ R
Sbjct: 232 QSPRITFEPQDVEVPSGNTVYFTCRAEGNPK---PEIIWIHNNH-SLDLEDDTRLNVFDD 287
Query: 90 STLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMT 149
TL + + + G Y C +A ++ + +T+SA+ + S +P + + E++
Sbjct: 288 GTLMIRNTRESDQGVYQC--MARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQDTEVLI-- 343
Query: 150 EGRELVIPCRVTS---PNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLT 206
G + C T P IT T + L DG R + S G + N T ++ G T
Sbjct: 344 -GTSTTLECMATGHPHPLITWTRD----NGLELDGSRHVATS-SGLYLQNITQRDHGRFT 397
Query: 207 CEATVNGHLYKTNYLTHRQTNTIIDVQIS---TPRPVKLLRGHTLVLNCTATTPLNTRVQ 263
C A N H N I+ TP+ +L H + C A N
Sbjct: 398 CHAN-NSH-----GTVQAAANIIVQAPPQFTVTPKDQVVLEEHAVEWLCEADG--NPPPV 449
Query: 264 MTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVN 323
+ W+ ++ H + L ID+ D+G Y C+ S K V+
Sbjct: 450 IVWT---------KTGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVS 500
Query: 324 TSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARY 383
+ + KA Q V ++ +S + P P + W K+G+ TE +
Sbjct: 501 VQLTVKPKALAVFTQLPQDTSVEVG--KNINISCHAQGEPQPIITWNKEGVQITESGKFH 558
Query: 384 LTRGYSLIIKDVTEEDAGNYTIL----LSIKQSNVFKNLTA 420
+ +L I D D G Y + + +N+F +TA
Sbjct: 559 VDDEGTLTIYDAGFPDQGRYECVARNSFGLAVTNMFLTVTA 599
Score = 48.5 bits (114), Expect = 2e-05
Identities = 69/331 (20%), Positives = 119/331 (35%), Gaps = 33/331 (9%)
Query: 143 PEIIHMTEGRELVIPCRVTS---PNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATY 199
P+ + + G + CR P I LD + D R+ +I N
Sbjct: 240 PQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLD--LEDDTRLNVFDDGTLMIRNTRE 297
Query: 200 KEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQ-ISTPRPVKLLRGHTLVLNCTATTPL 258
+ G+ C A + KT R ++ + P+ ++L G + L C AT
Sbjct: 298 SDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQDTEVLIGTSTTLECMATG-- 355
Query: 259 NTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPS 318
+ +TW+ + S R + S+ L + + +D G +TC +
Sbjct: 356 HPHPLITWTRDNGLELDGS--RHVATSSG--------LYLQNITQRDHGRFTCHANNSHG 405
Query: 319 FKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATE 378
++ + TV + Q VLE + + + P P +VW K G
Sbjct: 406 TVQAAANIIVQAPPQFTVTPKDQVVLE----EHAVEWLCEADGNPPPVIVWTKTGGQLPV 461
Query: 379 KSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSF 438
+ + +L I + D G Y ++ V K V+V+ + KA++ F
Sbjct: 462 EGQHTVLSSGTLRIDRAAQHDQGQYECQ-AVSSLGVKK-------VSVQLTVKPKALAVF 513
Query: 439 ---PDPALYPLGSRQILTCTAYGIPQPTIKW 466
P +G ++C A G PQP I W
Sbjct: 514 TQLPQDTSVEVGKNINISCHAQGEPQPIITW 544
>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
Length = 1447
Score = 60.8 bits (146), Expect = 3e-09
Identities = 53/180 (29%), Positives = 83/180 (46%), Gaps = 21/180 (11%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTS-VHIYDKAFITVKHRKQQVLE------TVA 348
L I ++Q D G+Y C R+ S ++ N + V I + HR+ L+ +
Sbjct: 197 LQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGL---HRQLYFLQRPSNVVAIE 253
Query: 349 GKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARY-LTRGYSLIIKDVTEEDAGNYTILL 407
GK + L V +P P WL+ +S +Y L G +L+I +VT++D+G YT ++
Sbjct: 254 GKDAV-LECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVV 312
Query: 408 SIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQI-LTCTAYGIPQPTIKW 466
+ K N+ + +A L V V P + LY S I CT G P PT+ W
Sbjct: 313 TYKNENI--SASAELTVLVPPWFLNHPSN------LYAYESMDIEFECTVSGKPVPTVNW 364
Score = 35.0 bits (79), Expect = 0.17
Identities = 64/296 (21%), Positives = 104/296 (35%), Gaps = 33/296 (11%)
Query: 151 GRELVIPCRVTS-PNITVTLKKFPLD-TLIPDGKRIIWDSRKGFIISNATYKEIGLLTCE 208
G +++ C V P T+ +K D T IP R++ IS +IG+ C
Sbjct: 154 GDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCS 213
Query: 209 A-----TVNGHLYKTNYLT----HRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLN 259
A + G+ + L+ HRQ + P V + G VL C +
Sbjct: 214 ARNPASSRTGNEAEVRILSDPGLHRQLYFL-----QRPSNVVAIEGKDAVLECCVSG--Y 266
Query: 260 TRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSF 319
TW +E + +S ++ + S L I + + D G+YTC V ++
Sbjct: 267 PPPSFTWLRGEEVIQL--------RSKKYSLLGGSNLLISNVTDDDSGMYTCVV----TY 314
Query: 320 KSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEK 379
K+ N S + V P P V W+K+G
Sbjct: 315 KNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPS 374
Query: 380 SARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAV 435
+ G +L I V + D G Y + + N T+ ++ KP I +V
Sbjct: 375 DYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNA---QTSAQLIVPKPAIPSSSV 427
Score = 32.3 bits (72), Expect = 1.1
Identities = 47/236 (19%), Positives = 85/236 (36%), Gaps = 8/236 (3%)
Query: 234 ISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFY 293
+S P +RG ++L+C+A + V + W D + + R Q ++ + +
Sbjct: 43 LSEPSDAVTMRGGNVLLDCSAESDRGVPV-IKWK-KDGIHLALGMDERKQQLSNGSLLIQ 100
Query: 294 SVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSY 353
++L + D+GLY C G S ++ + + + + + V T +
Sbjct: 101 NILH-SRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESV--TAFMGDTV 157
Query: 354 RLSMKVKAFPSPEVVWLK---DGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIK 410
L +V P P + W K D P S + +L I + D G Y
Sbjct: 158 LLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNP 217
Query: 411 QSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
S+ N I++ + P + G +L C G P P+ W
Sbjct: 218 ASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTW 273
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 60.1 bits (144), Expect = 5e-09
Identities = 94/433 (21%), Positives = 165/433 (38%), Gaps = 64/433 (14%)
Query: 32 PELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPEMV-SKESERLSITKSACGRNGKQFCS 90
P ++ + + +G T++ CR E K PE++ + + LS+ + R
Sbjct: 246 PRITSEPQDADVTSGNTVYFTCRAEGNPK---PEIIWLRNNNELSMKTDS--RLNLLDDG 300
Query: 91 TLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTE 150
TL + Q G Y C +A + + +T+ + RP + + E++
Sbjct: 301 TLMIQNTQETDQGIYQC--MAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVL---V 355
Query: 151 GRELVIPCRVTS---PNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTC 207
G + + C T P I+ T T +P R+ G I N + G C
Sbjct: 356 GESVTLECSATGHPPPRISWTRGD---RTPLPVDPRVNITPSGGLYIQNVVQGDSGEYAC 412
Query: 208 EATVN-GHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTW 266
AT N ++ T ++ + TP+ ++ G T+ C A N + W
Sbjct: 413 SATNNIDSVHATAFIIVQALPQFT----VTPQDRVVIEGQTVDFQCEAKG--NPPPVIAW 466
Query: 267 SYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSV 326
+ + + SV RR H + L I + D+G Y C+ +VN
Sbjct: 467 T---KGGSQLSVDRR------HLVLSSGTLRISGVALHDQGQYECQ--------AVNIIG 509
Query: 327 HIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVK------AFPSPEVVWLKDGLPATEKS 380
A +TV+ R V ++ + + V+ P P + W KDG+ TE
Sbjct: 510 SQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESG 569
Query: 381 ARYLTRGYSLIIKDVTEEDAGNY-------------TILLSIKQSNVFKN---LTATLIV 424
+++ L I DV DAG Y +++LS+ +V +N AT IV
Sbjct: 570 KFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRNGDPFVATSIV 629
Query: 425 NVKPQIYEKAVSS 437
+ ++A++S
Sbjct: 630 EAIATV-DRAINS 641
Score = 53.1 bits (126), Expect = 6e-07
Identities = 61/277 (22%), Positives = 105/277 (37%), Gaps = 24/277 (8%)
Query: 193 IISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTII-DVQISTPRPVKLLRGHTLVLN 251
+I N + G+ C A KT +T R + + P+ ++L G ++ L
Sbjct: 303 MIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLE 362
Query: 252 CTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTC 311
C+AT R+ +W+ D R I S L I + D G Y C
Sbjct: 363 CSATGHPPPRI--SWTRGDRTPLPVDPRVNITPSGG--------LYIQNVVQGDSGEYAC 412
Query: 312 RVRSGPSFKSVNTSVHIYDKAF--ITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVW 369
+ + SV+ + I +A TV + + V+E ++ + K P P + W
Sbjct: 413 SATN--NIDSVHATAFIIVQALPQFTVTPQDRVVIEG----QTVDFQCEAKGNPPPVIAW 466
Query: 370 LKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQ 429
K G + + +L I V D G Y + N+ + + V+P+
Sbjct: 467 TKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQY----ECQAVNIIGSQKVVAHLTVQPR 522
Query: 430 IYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
+ +S P +G+ L C++ G P+P I W
Sbjct: 523 V-TPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITW 558
>gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 1253
Score = 59.7 bits (143), Expect = 7e-09
Identities = 103/489 (21%), Positives = 190/489 (38%), Gaps = 70/489 (14%)
Query: 9 VLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQT--LHLQCRG----EAAHKWS 62
+LLC+ + + G + +P + + + + T + L+C E +W+
Sbjct: 11 LLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWT 70
Query: 63 LPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETES 122
+ K E L +T +G + N AQ G Y C S K T
Sbjct: 71 RDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQ-RFQGIYRCF-----ASNKLGTAM 124
Query: 123 AIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPC---------RVTSPNITVT-LKKF 172
+ I + G P + E + + + EG +V+PC R+ N + +K+
Sbjct: 125 SHEIRLMAEGAP--KWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQD 182
Query: 173 PLDTLIPDGK----RIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNT 228
T+ +G ++ I +A + + + ++ + TN + R+
Sbjct: 183 ERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL 242
Query: 229 IIDVQISTPRPVKLLRGHTLVLNCTAT---TPLNTRVQMTWSYPDEKNKRASVRRRIDQS 285
+ S+ + L+G LVL C A TP ++ + P + R+
Sbjct: 243 LFPTNSSSH--LVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---------RVTYQ 291
Query: 286 NSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVK------HR 339
N + L + K+ +D G Y C + S+ ++ H Y ++TV+ H+
Sbjct: 292 NHN-----KTLQLLKVGEEDDGEYRCLAEN-----SLGSARHAY---YVTVEAAPYWLHK 338
Query: 340 KQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATE--KSARYLTRGYSLIIKDVTE 397
Q L + RL +V+ P PEV W +G+P E K +Y + +LI+ +V
Sbjct: 339 PQSHL--YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQP 396
Query: 398 EDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAY 457
D T++ + N L A + V Q+ K +++ + GS L C A+
Sbjct: 397 SD----TMVTQCEARNRHGLLLANAYIYV-VQLPAKILTADNQTYMAVQGSTAYLLCKAF 451
Query: 458 GIPQPTIKW 466
G P P+++W
Sbjct: 452 GAPVPSVQW 460
Score = 45.1 bits (105), Expect = 2e-04
Identities = 46/176 (26%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
L + +Q D + C R+ N +++ + Q V G +Y L
Sbjct: 389 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLP-AKILTADNQTYMAVQGSTAYLL 447
Query: 356 SMKVKAF--PSPEVVWL-KDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQS 412
KAF P P V WL +DG + + +L I+D+ D G Y L + Q+
Sbjct: 448 C---KAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQN 504
Query: 413 NVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIP--QPTIKW 466
NV T++ N+K + + ++ P + GSR TC A P QP+I W
Sbjct: 505 NV------TIMANLKVKDATQ-ITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW 553
Score = 38.1 bits (87), Expect = 0.021
Identities = 59/264 (22%), Positives = 95/264 (35%), Gaps = 22/264 (8%)
Query: 151 GRELVIPCRVTS---PNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTC 207
G + C+V P +T + P++ L D K I R I+SN + + C
Sbjct: 347 GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI--QRGALILSNVQPSDTMVTQC 404
Query: 208 EA-TVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTW 266
EA +G L Y+ Q + + + ++G T L C A VQ
Sbjct: 405 EARNRHGLLLANAYIYVVQLPA--KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQ--- 459
Query: 267 SYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSV 326
+ DE R +AN L I +Q D G Y C + + ++ ++
Sbjct: 460 -WLDEDGTTVLQDERFFP---YAN---GTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 512
Query: 327 HIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATE--KSARYL 384
+ D IT R +E + ++ P + W DG E S +Y
Sbjct: 513 KVKDATQITQGPRS--TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 570
Query: 385 TRGYSLIIKDVTEEDAGNYTILLS 408
L+I + D GNY+ + S
Sbjct: 571 IEDGRLVIHSLDYSDQGNYSCVAS 594
>gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 1257
Score = 59.7 bits (143), Expect = 7e-09
Identities = 103/489 (21%), Positives = 190/489 (38%), Gaps = 70/489 (14%)
Query: 9 VLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQT--LHLQCRG----EAAHKWS 62
+LLC+ + + G + +P + + + + T + L+C E +W+
Sbjct: 11 LLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWT 70
Query: 63 LPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETES 122
+ K E L +T +G + N AQ G Y C S K T
Sbjct: 71 RDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQ-RFQGIYRCF-----ASNKLGTAM 124
Query: 123 AIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPC---------RVTSPNITVT-LKKF 172
+ I + G P + E + + + EG +V+PC R+ N + +K+
Sbjct: 125 SHEIRLMAEGAP--KWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQD 182
Query: 173 PLDTLIPDGK----RIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNT 228
T+ +G ++ I +A + + + ++ + TN + R+
Sbjct: 183 ERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL 242
Query: 229 IIDVQISTPRPVKLLRGHTLVLNCTAT---TPLNTRVQMTWSYPDEKNKRASVRRRIDQS 285
+ S+ + L+G LVL C A TP ++ + P + R+
Sbjct: 243 LFPTNSSSH--LVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---------RVTYQ 291
Query: 286 NSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVK------HR 339
N + L + K+ +D G Y C + S+ ++ H Y ++TV+ H+
Sbjct: 292 NHN-----KTLQLLKVGEEDDGEYRCLAEN-----SLGSARHAY---YVTVEAAPYWLHK 338
Query: 340 KQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATE--KSARYLTRGYSLIIKDVTE 397
Q L + RL +V+ P PEV W +G+P E K +Y + +LI+ +V
Sbjct: 339 PQSHL--YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQP 396
Query: 398 EDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAY 457
D T++ + N L A + V Q+ K +++ + GS L C A+
Sbjct: 397 SD----TMVTQCEARNRHGLLLANAYIYV-VQLPAKILTADNQTYMAVQGSTAYLLCKAF 451
Query: 458 GIPQPTIKW 466
G P P+++W
Sbjct: 452 GAPVPSVQW 460
Score = 45.1 bits (105), Expect = 2e-04
Identities = 46/176 (26%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
L + +Q D + C R+ N +++ + Q V G +Y L
Sbjct: 389 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLP-AKILTADNQTYMAVQGSTAYLL 447
Query: 356 SMKVKAF--PSPEVVWL-KDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQS 412
KAF P P V WL +DG + + +L I+D+ D G Y L + Q+
Sbjct: 448 C---KAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQN 504
Query: 413 NVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIP--QPTIKW 466
NV T++ N+K + + ++ P + GSR TC A P QP+I W
Sbjct: 505 NV------TIMANLKVKDATQ-ITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW 553
Score = 38.1 bits (87), Expect = 0.021
Identities = 59/264 (22%), Positives = 95/264 (35%), Gaps = 22/264 (8%)
Query: 151 GRELVIPCRVTS---PNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTC 207
G + C+V P +T + P++ L D K I R I+SN + + C
Sbjct: 347 GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI--QRGALILSNVQPSDTMVTQC 404
Query: 208 EA-TVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTW 266
EA +G L Y+ Q + + + ++G T L C A VQ
Sbjct: 405 EARNRHGLLLANAYIYVVQLPA--KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQ--- 459
Query: 267 SYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSV 326
+ DE R +AN L I +Q D G Y C + + ++ ++
Sbjct: 460 -WLDEDGTTVLQDERFFP---YAN---GTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 512
Query: 327 HIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATE--KSARYL 384
+ D IT R +E + ++ P + W DG E S +Y
Sbjct: 513 KVKDATQITQGPRS--TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 570
Query: 385 TRGYSLIIKDVTEEDAGNYTILLS 408
L+I + D GNY+ + S
Sbjct: 571 IEDGRLVIHSLDYSDQGNYSCVAS 594
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 59.7 bits (143), Expect = 7e-09
Identities = 80/329 (24%), Positives = 123/329 (37%), Gaps = 54/329 (16%)
Query: 175 DTLIPDGKRI--IW--DSRKGFIISNATYKEIGLLTC----------EATVNGHLYKTNY 220
+ L P+ +RI +W DS I NA + G+ C EATVN +++
Sbjct: 60 EKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLM 119
Query: 221 LTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRR 280
+ P P + G V+ C + L + W + R
Sbjct: 120 FKN------------APTPQEFREGEDAVIVCDVVSSLPPTI--IWKHKGRDVILKKDVR 165
Query: 281 RIDQSNSHANIFYSVLTIDKMQNKDKGLYTCR----VRSGPSFKSVNTSVHIYDKAFITV 336
I SN++ L I ++ D+G Y C R +FK + V++ T+
Sbjct: 166 FIVLSNNY-------LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPP----TI 214
Query: 337 KHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDG--LPATEKSARYLTRGYS--LII 392
+ R+ V T +S L + FP P + W KDG + E +Y+ S L I
Sbjct: 215 QARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTI 274
Query: 393 KDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQIL 452
K V + D Y + K ++ T L V KP+I + + L + L
Sbjct: 275 KKVDKNDEAEYICIAENKAGE--QDATIHLKVFAKPKI-----TYVENQTAMELEEQVTL 327
Query: 453 TCTAYGIPQPTIKWFWHPCNHNHSEARCD 481
TC A G P P+I W N + E D
Sbjct: 328 TCEASGDPIPSITWRTSTRNISSEEKTLD 356
Score = 56.6 bits (135), Expect = 6e-08
Identities = 96/458 (20%), Positives = 166/458 (36%), Gaps = 62/458 (13%)
Query: 33 ELSLKGTQHIMQAGQTLHLQCR--GEAAHK---WSLP--EMVSKESERLSITKSACGRNG 85
++ + +Q + G++ C+ G+A K W P E ++ +R+S+ +
Sbjct: 21 QVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWN------ 74
Query: 86 KQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEI 145
STLT+ A + G Y C V E+E+ + + I M+ P
Sbjct: 75 DDSSSTLTIYNANIDDAGIYKC---VVTGEDGSESEATVNVKIFQK-----LMFKNAPTP 126
Query: 146 IHMTEGRELVIPCRVTSP-NITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGL 204
EG + VI C V S T+ K D ++ R I S I + G
Sbjct: 127 QEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGT 186
Query: 205 LTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLN-TRVQ 263
CE G + + + I++V + ++ ++N TA + T V
Sbjct: 187 YRCE----GRILARGEINFKDIQVIVNVPPT-------IQARQNIVNATANLGQSVTLVC 235
Query: 264 MTWSYPDEKNKRASVRRRIDQSNSHANIFYS----VLTIDKMQNKDKGLYTCRVRSGPSF 319
+P+ +I+Q +S LTI K+ D+ Y C +
Sbjct: 236 DAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGE 295
Query: 320 KSVNTSVHIYDKAFIT-VKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKD--GLPA 376
+ + ++ K IT V+++ LE L+ + P P + W + +
Sbjct: 296 QDATIHLKVFAKPKITYVENQTAMELE-----EQVTLTCEASGDPIPSITWRTSTRNISS 350
Query: 377 TEKS------ARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQI 430
EK+ R R SL +K + DAG Y S +++ L V P++
Sbjct: 351 EEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMY--LEVQYAPKL 408
Query: 431 YEKAVSSFPDPALYPLGSRQI-LTCTAYGIPQPTIKWF 467
A+Y Q+ +TC + P TI WF
Sbjct: 409 QGPV-------AVYTWEGNQVNITCEVFAYPSATISWF 439
Score = 32.7 bits (73), Expect = 0.87
Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 12/122 (9%)
Query: 287 SHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLET 346
SHA + S LT+ +Q D G Y C + S +Y + K + + T
Sbjct: 363 SHARV--SSLTLKSIQYTDAGEYICTASNTIG----QDSQSMYLEVQYAPKLQGPVAVYT 416
Query: 347 VAGKRSYRLSMKVKAFPSPEVVWLKDG--LPATEKSARYLTRGYSLIIKDVT---EEDAG 401
G + ++ +V A+PS + W +DG LP++ S + S +VT E D G
Sbjct: 417 WEGNQ-VNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFG 475
Query: 402 NY 403
NY
Sbjct: 476 NY 477
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 59.7 bits (143), Expect = 7e-09
Identities = 80/329 (24%), Positives = 123/329 (37%), Gaps = 54/329 (16%)
Query: 175 DTLIPDGKRI--IW--DSRKGFIISNATYKEIGLLTC----------EATVNGHLYKTNY 220
+ L P+ +RI +W DS I NA + G+ C EATVN +++
Sbjct: 60 EKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLM 119
Query: 221 LTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRR 280
+ P P + G V+ C + L + W + R
Sbjct: 120 FKN------------APTPQEFREGEDAVIVCDVVSSLPPTI--IWKHKGRDVILKKDVR 165
Query: 281 RIDQSNSHANIFYSVLTIDKMQNKDKGLYTCR----VRSGPSFKSVNTSVHIYDKAFITV 336
I SN++ L I ++ D+G Y C R +FK + V++ T+
Sbjct: 166 FIVLSNNY-------LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPP----TI 214
Query: 337 KHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDG--LPATEKSARYLTRGYS--LII 392
+ R+ V T +S L + FP P + W KDG + E +Y+ S L I
Sbjct: 215 QARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTI 274
Query: 393 KDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQIL 452
K V + D Y + K ++ T L V KP+I + + L + L
Sbjct: 275 KKVDKNDEAEYICIAENKAGE--QDATIHLKVFAKPKI-----TYVENQTAMELEEQVTL 327
Query: 453 TCTAYGIPQPTIKWFWHPCNHNHSEARCD 481
TC A G P P+I W N + E D
Sbjct: 328 TCEASGDPIPSITWRTSTRNISSEEKTLD 356
Score = 56.6 bits (135), Expect = 6e-08
Identities = 96/458 (20%), Positives = 166/458 (36%), Gaps = 62/458 (13%)
Query: 33 ELSLKGTQHIMQAGQTLHLQCR--GEAAHK---WSLP--EMVSKESERLSITKSACGRNG 85
++ + +Q + G++ C+ G+A K W P E ++ +R+S+ +
Sbjct: 21 QVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWN------ 74
Query: 86 KQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEI 145
STLT+ A + G Y C V E+E+ + + I M+ P
Sbjct: 75 DDSSSTLTIYNANIDDAGIYKC---VVTGEDGSESEATVNVKIFQK-----LMFKNAPTP 126
Query: 146 IHMTEGRELVIPCRVTSP-NITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGL 204
EG + VI C V S T+ K D ++ R I S I + G
Sbjct: 127 QEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGT 186
Query: 205 LTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLN-TRVQ 263
CE G + + + I++V + ++ ++N TA + T V
Sbjct: 187 YRCE----GRILARGEINFKDIQVIVNVPPT-------IQARQNIVNATANLGQSVTLVC 235
Query: 264 MTWSYPDEKNKRASVRRRIDQSNSHANIFYS----VLTIDKMQNKDKGLYTCRVRSGPSF 319
+P+ +I+Q +S LTI K+ D+ Y C +
Sbjct: 236 DAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGE 295
Query: 320 KSVNTSVHIYDKAFIT-VKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKD--GLPA 376
+ + ++ K IT V+++ LE L+ + P P + W + +
Sbjct: 296 QDATIHLKVFAKPKITYVENQTAMELE-----EQVTLTCEASGDPIPSITWRTSTRNISS 350
Query: 377 TEKS------ARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQI 430
EK+ R R SL +K + DAG Y S +++ L V P++
Sbjct: 351 EEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMY--LEVQYAPKL 408
Query: 431 YEKAVSSFPDPALYPLGSRQI-LTCTAYGIPQPTIKWF 467
A+Y Q+ +TC + P TI WF
Sbjct: 409 QGPV-------AVYTWEGNQVNITCEVFAYPSATISWF 439
Score = 32.7 bits (73), Expect = 0.87
Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 12/122 (9%)
Query: 287 SHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLET 346
SHA + S LT+ +Q D G Y C + S +Y + K + + T
Sbjct: 363 SHARV--SSLTLKSIQYTDAGEYICTASNTIG----QDSQSMYLEVQYAPKLQGPVAVYT 416
Query: 347 VAGKRSYRLSMKVKAFPSPEVVWLKDG--LPATEKSARYLTRGYSLIIKDVT---EEDAG 401
G + ++ +V A+PS + W +DG LP++ S + S +VT E D G
Sbjct: 417 WEGNQ-VNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFG 475
Query: 402 NY 403
NY
Sbjct: 476 NY 477
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 59.7 bits (143), Expect = 7e-09
Identities = 78/332 (23%), Positives = 141/332 (42%), Gaps = 44/332 (13%)
Query: 151 GRELVIPCRVTSPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEI--GLLTCE 208
GR+ I CRV ++K + L+P R + G + + KE+ G TC
Sbjct: 518 GRDTYIHCRVIGYPY-YSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCN 576
Query: 209 ATVNGHLYKTNYLTHRQTNTIIDVQISTP---RPVKLLR---GHTLVLNCTATTPLNTRV 262
V L T+ + V + P +P + R G + + C + + +
Sbjct: 577 VLVQPQL---------STSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSG-DLPI 626
Query: 263 QMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSV 322
+TW D + S+ ID + F S L I + G YTC R+ +
Sbjct: 627 TITWQ-KDGRPIPGSLGVTIDNID-----FTSSLRISNLSLMHNGNYTCIARNEAAAVEH 680
Query: 323 NTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKD---GLPATEK 379
+ + + V+ R Q + + GK + L+ + +P P +VW G+P +
Sbjct: 681 QSQLIVRVPPKFVVQPRDQ---DGIYGK-AVILNCSAEGYPVPTIVWKFSKGAGVPQFQP 736
Query: 380 SA-----RYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKA 434
A + L+ G SL+IK V EED+G Y +S ++V +++ ++ + VK
Sbjct: 737 IALNGRIQVLSNG-SLLIKHVVEEDSGYYLCKVS---NDVGADVSKSMYLTVK---IPAM 789
Query: 435 VSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
++S+P+ L G ++ ++CTA+G ++W
Sbjct: 790 ITSYPNTTLATQGQKKEMSCTAHGEKPIIVRW 821
Score = 47.0 bits (110), Expect = 4e-05
Identities = 58/238 (24%), Positives = 98/238 (41%), Gaps = 34/238 (14%)
Query: 241 KLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDK 300
K +RG+ V C + + + + D + + R I + + L I
Sbjct: 134 KTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGA--------LYIKD 185
Query: 301 MQNKDKGLYTCRV-----RSGPSFKSVNTSVHIYDKAFITVK------HRKQQVLETVAG 349
+QN+D GLY R +G + +S + + + D A HRK +AG
Sbjct: 186 VQNED-GLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRK-----AMAG 239
Query: 350 KRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSI 409
+R L K P P+ WLKD +P E S R+ L+I+++ D+G+Y +S
Sbjct: 240 QR-VELPCKALGHPEPDYRWLKDNMP-LELSGRFQKTVTGLLIENIRPSDSGSYVCEVSN 297
Query: 410 KQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF 467
+ TA +I + + KA S P +GS+ L+C+ G + W+
Sbjct: 298 RYG------TAKVIGRLYVKQPLKATIS-PRKVKSSVGSQVSLSCSVTGTEDQELSWY 348
Score = 37.4 bits (85), Expect = 0.035
Identities = 40/173 (23%), Positives = 72/173 (41%), Gaps = 12/173 (6%)
Query: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRL 355
L I+ ++ D G Y C V + V +++ T+ RK V +V + S L
Sbjct: 278 LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRK--VKSSVGSQVS--L 333
Query: 356 SMKVKAFPSPEVVWLKDG-LPATEKSARYLTRGYSLIIKD-VTEEDAGNYTILLSIKQSN 413
S V E+ W ++G + K+ R + +I D + + D G Y + K
Sbjct: 334 SCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVR-KDKL 392
Query: 414 VFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
++ ++ + P+I +S+F + + P ++ C G P PTI W
Sbjct: 393 SAQDYVQVVLEDGTPKI----ISAFSEKVVSPAEPVSLM-CNVKGTPLPTITW 440
Score = 32.0 bits (71), Expect = 1.5
Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 4/56 (7%)
Query: 355 LSMKVKAFPSPEVVWLKD--GLPA--TEKSARYLTRGYSLIIKDVTEEDAGNYTIL 406
L K PSP V W+KD G P+ T R + S II+ V ED+G Y+ +
Sbjct: 1305 LPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCI 1360
>gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo
sapiens]
Length = 858
Score = 59.3 bits (142), Expect = 9e-09
Identities = 77/314 (24%), Positives = 119/314 (37%), Gaps = 54/314 (17%)
Query: 175 DTLIPDGKRI--IW--DSRKGFIISNATYKEIGLLTC----------EATVNGHLYKTNY 220
+ L P+ +RI +W DS I NA + G+ C EATVN +++
Sbjct: 60 EKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLM 119
Query: 221 LTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRR 280
+ P P + G V+ C + L + W + R
Sbjct: 120 FKN------------APTPQEFREGEDAVIVCDVVSSLPPTI--IWKHKGRDVILKKDVR 165
Query: 281 RIDQSNSHANIFYSVLTIDKMQNKDKGLYTCR----VRSGPSFKSVNTSVHIYDKAFITV 336
I SN++ L I ++ D+G Y C R +FK + V++ T+
Sbjct: 166 FIVLSNNY-------LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPP----TI 214
Query: 337 KHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDG--LPATEKSARYLTRGYS--LII 392
+ R+ V T +S L + FP P + W KDG + E +Y+ S L I
Sbjct: 215 QARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTI 274
Query: 393 KDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQIL 452
K V + D Y + K ++ T L V KP+I + + L + L
Sbjct: 275 KKVDKNDEAEYICIAENKAGE--QDATIHLKVFAKPKI-----TYVENQTAMELEEQVTL 327
Query: 453 TCTAYGIPQPTIKW 466
TC A G P P+I W
Sbjct: 328 TCEASGDPIPSITW 341
Score = 53.1 bits (126), Expect = 6e-07
Identities = 96/468 (20%), Positives = 167/468 (35%), Gaps = 72/468 (15%)
Query: 33 ELSLKGTQHIMQAGQTLHLQCR--GEAAHK---WSLP--EMVSKESERLSITKSACGRNG 85
++ + +Q + G++ C+ G+A K W P E ++ +R+S+ +
Sbjct: 21 QVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWN------ 74
Query: 86 KQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEI 145
STLT+ A + G Y C V E+E+ + + I M+ P
Sbjct: 75 DDSSSTLTIYNANIDDAGIYKC---VVTGEDGSESEATVNVKIFQK-----LMFKNAPTP 126
Query: 146 IHMTEGRELVIPCRVTSP-NITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGL 204
EG + VI C V S T+ K D ++ R I S I + G
Sbjct: 127 QEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGT 186
Query: 205 LTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLN-TRVQ 263
CE G + + + I++V + ++ ++N TA + T V
Sbjct: 187 YRCE----GRILARGEINFKDIQVIVNVPPT-------IQARQNIVNATANLGQSVTLVC 235
Query: 264 MTWSYPDEKNKRASVRRRIDQSNSHANIFYS----VLTIDKMQNKDKGLYTCRVRSGPSF 319
+P+ +I+Q +S LTI K+ D+ Y C +
Sbjct: 236 DAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGE 295
Query: 320 KSVNTSVHIYDKAFIT-VKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKD--GLPA 376
+ + ++ K IT V+++ LE L+ + P P + W + +
Sbjct: 296 QDATIHLKVFAKPKITYVENQTAMELE-----EQVTLTCEASGDPIPSITWRTSTRNISS 350
Query: 377 TEKSA----------------RYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTA 420
EK++ R R SL +K + DAG Y S +++
Sbjct: 351 EEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMY- 409
Query: 421 TLIVNVKPQIYEKAVSSFPDPALYPLGSRQI-LTCTAYGIPQPTIKWF 467
L V P++ A+Y Q+ +TC + P TI WF
Sbjct: 410 -LEVQYAPKLQGPV-------AVYTWEGNQVNITCEVFAYPSATISWF 449
Score = 35.4 bits (80), Expect = 0.13
Identities = 40/156 (25%), Positives = 68/156 (43%), Gaps = 16/156 (10%)
Query: 253 TATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCR 312
T+T +++ + +W+ P EK + + SHA + S LT+ +Q D G Y C
Sbjct: 343 TSTRNISSEEKASWTRP-EKQETLDGHMVV---RSHARV--SSLTLKSIQYTDAGEYICT 396
Query: 313 VRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKD 372
+ S +Y + K + + T G + ++ +V A+PS + W +D
Sbjct: 397 ASNTIG----QDSQSMYLEVQYAPKLQGPVAVYTWEGNQ-VNITCEVFAYPSATISWFRD 451
Query: 373 G--LPATEKSARYLTRGYSLIIKDVT---EEDAGNY 403
G LP++ S + S +VT E D GNY
Sbjct: 452 GQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNY 487
>gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]
Length = 2623
Score = 59.3 bits (142), Expect = 9e-09
Identities = 100/468 (21%), Positives = 193/468 (41%), Gaps = 70/468 (14%)
Query: 32 PELSLKGTQHI-MQAGQTLHLQCRGEAAHKWSLPEMVSKESERLSITKSACGRNGKQFC- 89
P + + T+ I + +G T+ L+CR E ++ +++ ++ +++S+ G
Sbjct: 1745 PRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTV---VSESSQGSRQAVVTV 1801
Query: 90 -STLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHM 148
TL L+ GFY C + + ++ + I P V + + ++I
Sbjct: 1802 DGTLVLHNLSIYDRGFYKC------VASNPGGQDSLLVKIQVIAAPPV-ILEQRRQVIVG 1854
Query: 149 TEGRELVIPCRVTSPNITVTLKKFPLDTL---IPDG---KRIIWDSRKGFIISNATY--- 199
T G L +PC T K P ++ + DG K + + + K F+ SN T
Sbjct: 1855 TWGESLKLPC---------TAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIR 1905
Query: 200 ----KEIGLLTCEATVN-GHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTA 254
+ G C AT + G + LT + T ++ ++ + ++ G L+LNC+A
Sbjct: 1906 NLASSDRGTYECIATSSTGSERRVVMLTMEERVTSPRIEAASQKRTEVNFGDKLLLNCSA 1965
Query: 255 TTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIF-YSVLTIDKMQNKDKGLYTC-- 311
T + Q+ W P + +V + + S +++ L I + KD G+Y C
Sbjct: 1966 TG--EPKPQIMWRLPSK-----AVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVYLCVA 2018
Query: 312 RVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVW-L 370
R + G ++ S+ + ++ ++QVL + +++ K P PE+ W L
Sbjct: 2019 RNKMGDDLILMHVSLRLKPAKIDHKQYFRKQVLH----GKDFQVDCKASGSPVPEISWSL 2074
Query: 371 KDGL---------PATEKSARY-LTRGYSLIIKDVTEEDAGNYTILL--SIKQSNVFKNL 418
DG + ++ RY L +L V + G+YT ++ + + +L
Sbjct: 2075 PDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHL 2134
Query: 419 TATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
T ++ P+I + ++ A G +L C G P+P I W
Sbjct: 2135 T---VITAAPRIRQSNKTNKRIKA----GDTAVLDCEVTGDPKPKIFW 2175
Score = 48.1 bits (113), Expect = 2e-05
Identities = 94/450 (20%), Positives = 171/450 (38%), Gaps = 63/450 (14%)
Query: 46 GQTLHLQCRGEAAHK----WSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANH 101
G L L C K W LP + + + NG F ++T
Sbjct: 1956 GDKLLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVT-----EKD 2010
Query: 102 TGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEI--PEIIHMTEGRELVIPCR 159
+G Y C ++ K + I + +S +P + + +++H G++ + C+
Sbjct: 2011 SGVYLC------VARNKMGDDLILMHVSLRLKPAKIDHKQYFRKQVLH---GKDFQVDCK 2061
Query: 160 VTSPNITVTLKKFPLDTLIPDGKRIIWD---SRKGFIISNAT--YKEIGLL-----TCEA 209
+ + P T+I + + +R+ + +N T + ++G+ TC A
Sbjct: 2062 ASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYA 2121
Query: 210 TVNGHLYKTNYLTHRQTNTIID-VQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSY 268
L K H T ++ S ++ G T VL+C T + + ++ W
Sbjct: 2122 --QNTLGKDEMKVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVTG--DPKPKIFWLL 2177
Query: 269 PDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVR--SGPSFKSVNTSV 326
P + ID+ HAN LTI+K++ D G Y C R SG K V
Sbjct: 2178 PSND----MISFSIDRYTFHAN---GSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDV 2230
Query: 327 HIYDKAFITVKHRKQQVLETVAGKRSYR-LSMKVKAFPSPEVVWLKDG---LPATEKSAR 382
+ I + + V++ A + S + + + PSPEV+W+ L A +R
Sbjct: 2231 -VSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSR 2289
Query: 383 YLT-RGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAV-----S 436
+ +L I++V D+ ++ V +N ++ V+ ++ E +
Sbjct: 2290 ITVHKNGTLEIRNVRLSDSADFIC--------VARNEGGESVLVVQLEVLEMLRRPTFRN 2341
Query: 437 SFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
F + + LG L C+ G P P I W
Sbjct: 2342 PFNEKIVAQLGKSTALNCSVDGNPPPEIIW 2371
Score = 43.1 bits (100), Expect = 6e-04
Identities = 37/120 (30%), Positives = 48/120 (40%), Gaps = 10/120 (8%)
Query: 351 RSYRLSMKVKAFPSPEVVW-LKDGLPATEKSARY---LTRGYSLIIKDVTEEDAGNYTIL 406
+S L+ V P PE++W L +G + Y + S II T EDAG Y
Sbjct: 2353 KSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCA 2412
Query: 407 LSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
K + K L + KP I A P G L C + GIP+P IKW
Sbjct: 2413 ARNKVGYIEK--LVILEIGQKPVILTYA----PGTVKGISGESLSLHCVSDGIPKPNIKW 2466
Score = 41.6 bits (96), Expect = 0.002
Identities = 41/178 (23%), Positives = 74/178 (41%), Gaps = 16/178 (8%)
Query: 296 LTIDKMQNKDKGLYTCRVRS--GPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSY 353
L+I +++ +D+G Y C + G V SV Y + + R +++ TV +
Sbjct: 1708 LSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVVSYPPRIL--ERRTKEI--TVHSGSTV 1763
Query: 354 RLSMKVKAFPSPEVVWLKDGLPATEKSAR-----YLTRGYSLIIKDVTEEDAGNYTILLS 408
L + + PSP V W+ +S++ +T +L++ +++ D G Y + S
Sbjct: 1764 ELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVAS 1823
Query: 409 IKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
L ++ P I E+ + G L CTA G PQP++ W
Sbjct: 1824 -NPGGQDSLLVKIQVIAAPPVILEQRRQVI----VGTWGESLKLPCTAKGTPQPSVYW 1876
Score = 40.0 bits (92), Expect = 0.005
Identities = 42/175 (24%), Positives = 70/175 (40%), Gaps = 16/175 (9%)
Query: 298 IDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSM 357
I K +D G Y C R+ + + I K I ++ ++G+ S L
Sbjct: 2398 ISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTY--APGTVKGISGE-SLSLHC 2454
Query: 358 KVKAFPSPEVVWLKDGLPATEK---SARYLTRGY-SLIIKDVTEEDAGNYTILLSIKQSN 413
P P + W ++ + +Y+ +L+IK+ T D GNY + Q++
Sbjct: 2455 VSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNY---ICKAQNS 2511
Query: 414 VFKNLTAT--LIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKW 466
V L +IV P+I + P + G+ L C A G+P+P I W
Sbjct: 2512 VGHTLITVPVMIVAYPPRITNRP----PRSIVTRTGAAFQLHCVALGVPKPEITW 2562
Score = 35.0 bits (79), Expect = 0.17
Identities = 49/233 (21%), Positives = 87/233 (37%), Gaps = 20/233 (8%)
Query: 179 PDGKRIIWDSRKGFIISNATYKEIGLLTCEATVN-GHLYKTNYLTHRQTNTIIDVQISTP 237
P + + S FIIS T ++ G C A G++ K L Q I+ P
Sbjct: 2383 PQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTY---AP 2439
Query: 238 RPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLT 297
VK + G +L L+C + ++ W+ P V R + + L
Sbjct: 2440 GTVKGISGESLSLHCVSDGIPKPNIK--WTMPS-----GYVVDRPQINGKYILHDNGTLV 2492
Query: 298 IDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSM 357
I + D+G Y C+ ++ + V I + +R + + T G +++L
Sbjct: 2493 IKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYP-PRITNRPPRSIVTRTG-AAFQLHC 2550
Query: 358 KVKAFPSPEVVWLKDGLPATEKSARYLTRGY-------SLIIKDVTEEDAGNY 403
P PE+ W +++ T G +L+I++ D+G Y
Sbjct: 2551 VALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIY 2603
Score = 34.7 bits (78), Expect = 0.23
Identities = 51/218 (23%), Positives = 81/218 (37%), Gaps = 26/218 (11%)
Query: 108 KYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPC---RVTSPN 164
KY +K E + + I +P + Y+ P + G L + C + PN
Sbjct: 2408 KYRCAARNKVGYIEKLVILEIGQ--KPVILTYA--PGTVKGISGESLSLHCVSDGIPKPN 2463
Query: 165 ITVTLKK-FPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEATVN-GHLYKTNYLT 222
I T+ + +D +GK I+ D+ +I AT + G C+A + GH T +
Sbjct: 2464 IKWTMPSGYVVDRPQINGKYILHDNGT-LVIKEATAYDRGNYICKAQNSVGHTLITVPVM 2522
Query: 223 -----HRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRAS 277
R TN PR + G L+C A + ++TW PD +
Sbjct: 2523 IVAYPPRITNR-------PPRSIVTRTGAAFQLHCVALGV--PKPEITWEMPDHSLLSTA 2573
Query: 278 VRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRS 315
+ R S L I Q D G+Y C ++
Sbjct: 2574 SKERTHGSEQLH--LQGTLVIQNPQTSDSGIYKCTAKN 2609
>gi|142976733 surface glycoprotein, Ig superfamily member [Homo
sapiens]
Length = 1264
Score = 59.3 bits (142), Expect = 9e-09
Identities = 70/257 (27%), Positives = 105/257 (40%), Gaps = 29/257 (11%)
Query: 293 YSVLTIDKMQNKDKGLYTCRV--RSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGK 350
YS L D + D G Y+C +SG K V V++ + A I+ K + Q++ A
Sbjct: 272 YSHLATDSVDPADSGNYSCMAGNKSG-DVKYVTYMVNVLEHASIS-KGLQDQIVSLGA-- 327
Query: 351 RSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIK 410
+ + V P+P W + P SAR+LT G L I VT ED G Y +
Sbjct: 328 -TVHFTCDVHGNPAPNCTWFHNAQPI-HPSARHLTAGNGLKISGVTVEDVGMYQCVAD-- 383
Query: 411 QSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWF--- 467
F + T L + ++ + + P A G L+C A G+P P I+W+
Sbjct: 384 NGIGFMHSTGRLEIE-NDGGFKPVIITAPVSAKVADGDFVTLSCNASGLPVPVIRWYDSH 442
Query: 468 ----WHPCNHNHSEARCDFCSNNE------ESFILDADSNMGNRIESITQRMA---IIEG 514
HP S++R S E F+L I+++TQ A I E
Sbjct: 443 GLITSHPSQVLRSKSRKSQLSRPEGLNLEPVYFVLSQAGASSLHIQAVTQEHAGKYICEA 502
Query: 515 KNK--LPPANSSFMLPP 529
N+ A +S M+ P
Sbjct: 503 ANEHGTTQAEASLMVVP 519
Score = 53.9 bits (128), Expect = 4e-07
Identities = 61/224 (27%), Positives = 89/224 (39%), Gaps = 26/224 (11%)
Query: 271 EKNKRASVRRRI-DQSNSHANIFYSVLTIDKMQN-----KDKGLYTC--------RVRSG 316
E N +A VR +I + H+ Y +L +Q +DKG Y C +++
Sbjct: 145 ESNPKAEVRYKIRGKWLEHSTENYLILPSGNLQILNVSLEDKGSYKCAAYNPVTHQLKVE 204
Query: 317 PSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPA 376
P + + S D I Q + V + L V P+P+V WLKDG
Sbjct: 205 PIGRKLLVSRPSSDDVHILHPTHSQAL--AVLSRSPVTLECVVSGVPAPQVYWLKDGQDI 262
Query: 377 TEKSARYLTRGYSLIIKD-VTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAV 435
S R YS + D V D+GNY+ + K +V T +VNV + ++
Sbjct: 263 APGS--NWRRLYSHLATDSVDPADSGNYSCMAGNKSGDV---KYVTYMVNV---LEHASI 314
Query: 436 SSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEAR 479
S + LG+ TC +G P P WF H H AR
Sbjct: 315 SKGLQDQIVSLGATVHFTCDVHGNPAPNCTWF-HNAQPIHPSAR 357
Score = 29.6 bits (65), Expect = 7.3
Identities = 55/241 (22%), Positives = 94/241 (39%), Gaps = 47/241 (19%)
Query: 245 GHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNK 304
G +VL+C+A P+ TR+ +W + + +D + H I LTI + +
Sbjct: 43 GGPVVLHCSAQ-PVTTRI--SWLHNG---------KTLDGNLEHVKIHQGTLTILSLNSS 90
Query: 305 DKGLYTC-------RVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSM 357
G Y C + SGP+ SV + + KH + T K + +
Sbjct: 91 LLGYYQCLANNSIGAIVSGPA----TVSVAVLGDFGSSTKH-----VITAEEKSAGFIGC 141
Query: 358 KV-KAFPSPEVVWLKDGLPATEKSARYL-TRGYSLIIKDVTEEDAGNYTILLSIKQSNVF 415
+V ++ P EV + G + YL +L I +V+ ED G+Y + +
Sbjct: 142 RVPESNPKAEVRYKIRGKWLEHSTENYLILPSGNLQILNVSLEDKGSY-------KCAAY 194
Query: 416 KNLTATLIVN-VKPQIYEKAVSSFPDPALYPLGSRQI---------LTCTAYGIPQPTIK 465
+T L V + ++ SS L+P S+ + L C G+P P +
Sbjct: 195 NPVTHQLKVEPIGRKLLVSRPSSDDVHILHPTHSQALAVLSRSPVTLECVVSGVPAPQVY 254
Query: 466 W 466
W
Sbjct: 255 W 255
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,836,725
Number of Sequences: 37866
Number of extensions: 922233
Number of successful extensions: 5355
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 88
Number of HSP's successfully gapped in prelim test: 186
Number of HSP's that attempted gapping in prelim test: 3147
Number of HSP's gapped (non-prelim): 1574
length of query: 541
length of database: 18,247,518
effective HSP length: 107
effective length of query: 434
effective length of database: 14,195,856
effective search space: 6161001504
effective search space used: 6161001504
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.