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Search of human proteins with 22749373
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22749373 coiled-coil domain containing 111 [Homo sapiens]
(560 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22749373 coiled-coil domain containing 111 [Homo sapiens] 1150 0.0
gi|4506367 RAB3A, member RAS oncogene family [Homo sapiens] 35 0.18
gi|62241003 cardiomyopathy associated 5 [Homo sapiens] 31 2.6
gi|55749932 desmin [Homo sapiens] 30 4.5
gi|171906575 drebrin-like isoform c [Homo sapiens] 30 4.5
gi|62198235 drebrin-like isoform b [Homo sapiens] 30 4.5
gi|21361670 drebrin-like isoform a [Homo sapiens] 30 4.5
gi|81295809 pericentrin [Homo sapiens] 30 5.9
gi|75677574 cell cycle progression 1 isoform 2 [Homo sapiens] 30 5.9
gi|75677585 cell cycle progression 1 isoform 1 [Homo sapiens] 30 5.9
gi|24415404 MDN1, midasin homolog [Homo sapiens] 30 5.9
gi|4757966 Y chromosome chromodomain protein 1, telomeric isofor... 30 7.7
gi|25453481 Y chromosome chromodomain protein 1, telomeric isofo... 30 7.7
gi|51538581 chromodomain protein, Y-linked, 1B isoform b [Homo s... 30 7.7
gi|51538573 chromodomain protein, Y-linked, 1B isoform a [Homo s... 30 7.7
gi|124494231 dermatan sulfate epimerase precursor [Homo sapiens] 30 7.7
gi|7019521 dermatan sulfate epimerase precursor [Homo sapiens] 30 7.7
gi|150036262 chloride channel accessory 4 [Homo sapiens] 29 10.0
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 29 10.0
gi|110347427 ubiquitin specific protease 34 [Homo sapiens] 29 10.0
gi|57242757 calsyntenin 1 isoform 1 [Homo sapiens] 29 10.0
gi|57242755 calsyntenin 1 isoform 2 [Homo sapiens] 29 10.0
>gi|22749373 coiled-coil domain containing 111 [Homo sapiens]
Length = 560
Score = 1150 bits (2976), Expect = 0.0
Identities = 560/560 (100%), Positives = 560/560 (100%)
Query: 1 MNRKWEAKLKQIEERASHYERKPLSSVYRPRLSKPEEPPSIWRLFHRQAQAFNFVKSCKE 60
MNRKWEAKLKQIEERASHYERKPLSSVYRPRLSKPEEPPSIWRLFHRQAQAFNFVKSCKE
Sbjct: 1 MNRKWEAKLKQIEERASHYERKPLSSVYRPRLSKPEEPPSIWRLFHRQAQAFNFVKSCKE 60
Query: 61 DVHVFALECKVGDGQRIYLVTTYAEFWFYYKSRKNLLHCYEVIPENAVCKLYFDLEFNKP 120
DVHVFALECKVGDGQRIYLVTTYAEFWFYYKSRKNLLHCYEVIPENAVCKLYFDLEFNKP
Sbjct: 61 DVHVFALECKVGDGQRIYLVTTYAEFWFYYKSRKNLLHCYEVIPENAVCKLYFDLEFNKP 120
Query: 121 ANPGADGKKMVALLIEYVCKALQELYGVNCSAEDVLNLDSSTDEKFSRHLIFQLHDVAFK 180
ANPGADGKKMVALLIEYVCKALQELYGVNCSAEDVLNLDSSTDEKFSRHLIFQLHDVAFK
Sbjct: 121 ANPGADGKKMVALLIEYVCKALQELYGVNCSAEDVLNLDSSTDEKFSRHLIFQLHDVAFK 180
Query: 181 DNIHVGNFLRKILQPALDLLGSEDDDSAPETTGHGFPHFSEAPARQGFSFNKMFTEKATE 240
DNIHVGNFLRKILQPALDLLGSEDDDSAPETTGHGFPHFSEAPARQGFSFNKMFTEKATE
Sbjct: 181 DNIHVGNFLRKILQPALDLLGSEDDDSAPETTGHGFPHFSEAPARQGFSFNKMFTEKATE 240
Query: 241 ESWTSNSKKLERLGSAEQSSPDLSFLVVKNNMGEKHLFVDLGVYTRNRNFRLYKSSKIGK 300
ESWTSNSKKLERLGSAEQSSPDLSFLVVKNNMGEKHLFVDLGVYTRNRNFRLYKSSKIGK
Sbjct: 241 ESWTSNSKKLERLGSAEQSSPDLSFLVVKNNMGEKHLFVDLGVYTRNRNFRLYKSSKIGK 300
Query: 301 RVALEVTEDNKFFPIQSKDVSDEYQYFLSSLVSNVRFSDTLRILTCEPSQNKQKGVGYFN 360
RVALEVTEDNKFFPIQSKDVSDEYQYFLSSLVSNVRFSDTLRILTCEPSQNKQKGVGYFN
Sbjct: 301 RVALEVTEDNKFFPIQSKDVSDEYQYFLSSLVSNVRFSDTLRILTCEPSQNKQKGVGYFN 360
Query: 361 SIGTSVETIEGFQCSPYPEVDHFVLSLVNKDGIKGGIRRWNYFFPEELLVYDICKYRWCE 420
SIGTSVETIEGFQCSPYPEVDHFVLSLVNKDGIKGGIRRWNYFFPEELLVYDICKYRWCE
Sbjct: 361 SIGTSVETIEGFQCSPYPEVDHFVLSLVNKDGIKGGIRRWNYFFPEELLVYDICKYRWCE 420
Query: 421 NIGRAHKSNNIMILVDLKNEVWYQKCHDPVCKAENFKSDCFPLPAEVCLLFLFKEEEEFT 480
NIGRAHKSNNIMILVDLKNEVWYQKCHDPVCKAENFKSDCFPLPAEVCLLFLFKEEEEFT
Sbjct: 421 NIGRAHKSNNIMILVDLKNEVWYQKCHDPVCKAENFKSDCFPLPAEVCLLFLFKEEEEFT 480
Query: 481 TDEADETRSNETQNPHKPSPSRLSTGASADAVWDNGIDDAYFLEATEDAELAEAAENSLL 540
TDEADETRSNETQNPHKPSPSRLSTGASADAVWDNGIDDAYFLEATEDAELAEAAENSLL
Sbjct: 481 TDEADETRSNETQNPHKPSPSRLSTGASADAVWDNGIDDAYFLEATEDAELAEAAENSLL 540
Query: 541 SYNSEVDEIPDELIIEVLQE 560
SYNSEVDEIPDELIIEVLQE
Sbjct: 541 SYNSEVDEIPDELIIEVLQE 560
>gi|4506367 RAB3A, member RAS oncogene family [Homo sapiens]
Length = 220
Score = 35.0 bits (79), Expect = 0.18
Identities = 18/69 (26%), Positives = 31/69 (44%)
Query: 145 LYGVNCSAEDVLNLDSSTDEKFSRHLIFQLHDVAFKDNIHVGNFLRKILQPALDLLGSED 204
L G C ED + S + + HL F+ + + KDNI+V +++ + +
Sbjct: 132 LVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESL 191
Query: 205 DDSAPETTG 213
D + P TG
Sbjct: 192 DTADPAVTG 200
>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
Length = 4069
Score = 31.2 bits (69), Expect = 2.6
Identities = 29/122 (23%), Positives = 53/122 (43%), Gaps = 9/122 (7%)
Query: 217 PHFSEAPARQGFSFNKMFTEKAT---EESWTSNSKKLERLGSAEQSSPDLSFLVV----K 269
P SE A +++ EK T E K E + + S DLSF+ +
Sbjct: 2992 PDDSETVACHKTLKSRLEDEKVTPLKENKQKETHKTKEEIST--DSETDLSFIQPTIPSE 3049
Query: 270 NNMGEKHLFVDLGVYTRNRNFRLYKSSKIGKRVALEVTEDNKFFPIQSKDVSDEYQYFLS 329
+ EK+ +D + + + + ++++ EVTE+ FP+ S + + E++Y L
Sbjct: 3050 EDYFEKYTLIDYNISPDPEKQKAPQKLNVEEKLSKEVTEETISFPVSSVESALEHEYDLV 3109
Query: 330 SL 331
L
Sbjct: 3110 KL 3111
>gi|55749932 desmin [Homo sapiens]
Length = 470
Score = 30.4 bits (67), Expect = 4.5
Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 2/43 (4%)
Query: 507 ASADAVWDNGIDDAYFLEAT--EDAELAEAAENSLLSYNSEVD 547
A D DN +DD L+A E+ +L E AEN+L ++ ++VD
Sbjct: 174 ARVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVD 216
>gi|171906575 drebrin-like isoform c [Homo sapiens]
Length = 439
Score = 30.4 bits (67), Expect = 4.5
Identities = 11/31 (35%), Positives = 20/31 (64%)
Query: 10 KQIEERASHYERKPLSSVYRPRLSKPEEPPS 40
KQ+ + +H+ R+P +++ RPR P E P+
Sbjct: 297 KQLTQPETHFGREPAAAISRPRADLPAEEPA 327
>gi|62198235 drebrin-like isoform b [Homo sapiens]
Length = 430
Score = 30.4 bits (67), Expect = 4.5
Identities = 11/31 (35%), Positives = 20/31 (64%)
Query: 10 KQIEERASHYERKPLSSVYRPRLSKPEEPPS 40
KQ+ + +H+ R+P +++ RPR P E P+
Sbjct: 288 KQLTQPETHFGREPAAAISRPRADLPAEEPA 318
>gi|21361670 drebrin-like isoform a [Homo sapiens]
Length = 431
Score = 30.4 bits (67), Expect = 4.5
Identities = 11/31 (35%), Positives = 20/31 (64%)
Query: 10 KQIEERASHYERKPLSSVYRPRLSKPEEPPS 40
KQ+ + +H+ R+P +++ RPR P E P+
Sbjct: 289 KQLTQPETHFGREPAAAISRPRADLPAEEPA 319
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 30.0 bits (66), Expect = 5.9
Identities = 18/60 (30%), Positives = 29/60 (48%)
Query: 140 KALQELYGVNCSAEDVLNLDSSTDEKFSRHLIFQLHDVAFKDNIHVGNFLRKILQPALDL 199
KA+ L + L+ +S+ +K + L FQ DV KDN+ + L + Q L+L
Sbjct: 3010 KAVMSLLHTLEELKSDLSRPTSSQKKMAAELQFQFVDVLLKDNVSLTKALSTVTQEKLEL 3069
>gi|75677574 cell cycle progression 1 isoform 2 [Homo sapiens]
Length = 757
Score = 30.0 bits (66), Expect = 5.9
Identities = 43/196 (21%), Positives = 74/196 (37%), Gaps = 31/196 (15%)
Query: 202 SEDDDSAPETTGHGFPHFSEAPARQGFSFNKMFTEKATEESWTSNSKKL-ERLGSAEQSS 260
S+D+ S+ ET+ P F AR+ ++ E T SK+L +R S+ +
Sbjct: 158 SDDESSSDETSNQPSPAFRRRRARKKTVSASESEDRLVAEQETEPSKELSKRQFSSGLNK 217
Query: 261 PDLSFLVVKNNMGEKHLFVDLGVYTRNR-------------------------NFRLYKS 295
+ LV+ +MG H + + + R + +F YKS
Sbjct: 218 CVILALVIAISMGFGHFYGTIQIQKRQQLVRKIHEDELNDMKDYLSQCQQEQESFIDYKS 277
Query: 296 SKIGKRVALEVTEDNKF-FPIQSKDVSDEYQYFLSSLVSNVRFSDTLRILTCEPSQNKQK 354
K +TE K F Q +++ E QY SL + +L+ E ++
Sbjct: 278 LKENLARCWTLTEAEKMSFETQKTNLATENQYLRVSLEKEEKALSSLQ----EELNKLRE 333
Query: 355 GVGYFNSIGTSVETIE 370
+ GTS E ++
Sbjct: 334 QIRILEDKGTSTELVK 349
>gi|75677585 cell cycle progression 1 isoform 1 [Homo sapiens]
Length = 757
Score = 30.0 bits (66), Expect = 5.9
Identities = 43/196 (21%), Positives = 74/196 (37%), Gaps = 31/196 (15%)
Query: 202 SEDDDSAPETTGHGFPHFSEAPARQGFSFNKMFTEKATEESWTSNSKKL-ERLGSAEQSS 260
S+D+ S+ ET+ P F AR+ ++ E T SK+L +R S+ +
Sbjct: 158 SDDESSSDETSNQPSPAFRRRRARKKTVSASESEDRLVAEQETEPSKELSKRQFSSGLNK 217
Query: 261 PDLSFLVVKNNMGEKHLFVDLGVYTRNR-------------------------NFRLYKS 295
+ LV+ +MG H + + + R + +F YKS
Sbjct: 218 CVILALVIAISMGFGHFYGTIQIQKRQQLVRKIHEDELNDMKDYLSQCQQEQESFIDYKS 277
Query: 296 SKIGKRVALEVTEDNKF-FPIQSKDVSDEYQYFLSSLVSNVRFSDTLRILTCEPSQNKQK 354
K +TE K F Q +++ E QY SL + +L+ E ++
Sbjct: 278 LKENLARCWTLTEAEKMSFETQKTNLATENQYLRVSLEKEEKALSSLQ----EELNKLRE 333
Query: 355 GVGYFNSIGTSVETIE 370
+ GTS E ++
Sbjct: 334 QIRILEDKGTSTELVK 349
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 30.0 bits (66), Expect = 5.9
Identities = 24/81 (29%), Positives = 30/81 (37%), Gaps = 6/81 (7%)
Query: 474 KEEEEFTTDEADETRSNETQNPHKPSPSRLSTGASAD------AVWDNGIDDAYFLEATE 527
KE+ E EA+E ET SP G S D D G DD A
Sbjct: 4912 KEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQH 4971
Query: 528 DAELAEAAENSLLSYNSEVDE 548
E +E + S+ + E DE
Sbjct: 4972 PEEHSEEQQQSVEEKDKEADE 4992
>gi|4757966 Y chromosome chromodomain protein 1, telomeric isoform b
[Homo sapiens]
Length = 554
Score = 29.6 bits (65), Expect = 7.7
Identities = 22/85 (25%), Positives = 40/85 (47%), Gaps = 11/85 (12%)
Query: 230 FNKMFTEKATEESWTSNSKKLE---RLGSAEQSSPDLSFLVVKNNMGEKHLFVDLGVYTR 286
FN+ TEK + +WT+ S+ R ++ + + S K + +KH R
Sbjct: 54 FNRRQTEKQKKLTWTTTSRIFSNNARRRTSRSTKANYSKNSPKTPVTDKH--------HR 105
Query: 287 NRNFRLYKSSKIGKRVALEVTEDNK 311
++N +L+ +SK +R A + D K
Sbjct: 106 SKNRKLFAASKNVRRKAASILSDTK 130
>gi|25453481 Y chromosome chromodomain protein 1, telomeric isoform
a [Homo sapiens]
Length = 540
Score = 29.6 bits (65), Expect = 7.7
Identities = 22/85 (25%), Positives = 40/85 (47%), Gaps = 11/85 (12%)
Query: 230 FNKMFTEKATEESWTSNSKKLE---RLGSAEQSSPDLSFLVVKNNMGEKHLFVDLGVYTR 286
FN+ TEK + +WT+ S+ R ++ + + S K + +KH R
Sbjct: 54 FNRRQTEKQKKLTWTTTSRIFSNNARRRTSRSTKANYSKNSPKTPVTDKH--------HR 105
Query: 287 NRNFRLYKSSKIGKRVALEVTEDNK 311
++N +L+ +SK +R A + D K
Sbjct: 106 SKNRKLFAASKNVRRKAASILSDTK 130
>gi|51538581 chromodomain protein, Y-linked, 1B isoform b [Homo
sapiens]
Length = 554
Score = 29.6 bits (65), Expect = 7.7
Identities = 22/85 (25%), Positives = 40/85 (47%), Gaps = 11/85 (12%)
Query: 230 FNKMFTEKATEESWTSNSKKLE---RLGSAEQSSPDLSFLVVKNNMGEKHLFVDLGVYTR 286
FN+ TEK + +WT+ S+ R ++ + + S K + +KH R
Sbjct: 54 FNRRQTEKQKKLTWTTTSRIFSNNARRRTSRSTKANYSKNSPKTPVTDKH--------HR 105
Query: 287 NRNFRLYKSSKIGKRVALEVTEDNK 311
++N +L+ +SK +R A + D K
Sbjct: 106 SKNRKLFAASKNVRRKAASILSDTK 130
>gi|51538573 chromodomain protein, Y-linked, 1B isoform a [Homo
sapiens]
Length = 540
Score = 29.6 bits (65), Expect = 7.7
Identities = 22/85 (25%), Positives = 40/85 (47%), Gaps = 11/85 (12%)
Query: 230 FNKMFTEKATEESWTSNSKKLE---RLGSAEQSSPDLSFLVVKNNMGEKHLFVDLGVYTR 286
FN+ TEK + +WT+ S+ R ++ + + S K + +KH R
Sbjct: 54 FNRRQTEKQKKLTWTTTSRIFSNNARRRTSRSTKANYSKNSPKTPVTDKH--------HR 105
Query: 287 NRNFRLYKSSKIGKRVALEVTEDNK 311
++N +L+ +SK +R A + D K
Sbjct: 106 SKNRKLFAASKNVRRKAASILSDTK 130
>gi|124494231 dermatan sulfate epimerase precursor [Homo sapiens]
Length = 958
Score = 29.6 bits (65), Expect = 7.7
Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 8/45 (17%)
Query: 276 HLFVDLGVYTR--------NRNFRLYKSSKIGKRVALEVTEDNKF 312
H F D GV T NR+F +KS K+G R ++ NK+
Sbjct: 392 HYFEDWGVVTYGSALPAEINRSFLSFKSGKLGGRAIYDIVHRNKY 436
>gi|7019521 dermatan sulfate epimerase precursor [Homo sapiens]
Length = 958
Score = 29.6 bits (65), Expect = 7.7
Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 8/45 (17%)
Query: 276 HLFVDLGVYTR--------NRNFRLYKSSKIGKRVALEVTEDNKF 312
H F D GV T NR+F +KS K+G R ++ NK+
Sbjct: 392 HYFEDWGVVTYGSALPAEINRSFLSFKSGKLGGRAIYDIVHRNKY 436
>gi|150036262 chloride channel accessory 4 [Homo sapiens]
Length = 919
Score = 29.3 bits (64), Expect = 10.0
Identities = 16/45 (35%), Positives = 23/45 (51%)
Query: 484 ADETRSNETQNPHKPSPSRLSTGASADAVWDNGIDDAYFLEATED 528
A+ T E+QN H L GA AD+ ++G+ YF TE+
Sbjct: 627 ANVTAFIESQNGHTEVLELLDNGAGADSFKNDGVYSRYFTAYTEN 671
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 29.3 bits (64), Expect = 10.0
Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 5/65 (7%)
Query: 488 RSNETQNPHKPSPSRLSTGASADAVWDNGIDDAYFLEATEDAELAEAAENSLLSYNSEVD 547
R + + P +P+P R AD+ + +D+ + TED + E E Y+ + D
Sbjct: 61 RKTQDKQPQEPAPKRKPFAVKADS---SSVDECDDSDGTEDMDEKEEDEGE--EYSEDND 115
Query: 548 EIPDE 552
E DE
Sbjct: 116 EPGDE 120
>gi|110347427 ubiquitin specific protease 34 [Homo sapiens]
Length = 3546
Score = 29.3 bits (64), Expect = 10.0
Identities = 14/41 (34%), Positives = 21/41 (51%)
Query: 124 GADGKKMVALLIEYVCKALQELYGVNCSAEDVLNLDSSTDE 164
G +V+L E+V + +E Y V C D+ N+ S DE
Sbjct: 2007 GVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDE 2047
>gi|57242757 calsyntenin 1 isoform 1 [Homo sapiens]
Length = 981
Score = 29.3 bits (64), Expect = 10.0
Identities = 15/63 (23%), Positives = 29/63 (46%)
Query: 445 KCHDPVCKAENFKSDCFPLPAEVCLLFLFKEEEEFTTDEADETRSNETQNPHKPSPSRLS 504
K +D + + E +DC P +++C + + FT D+ ++ E N K +L+
Sbjct: 177 KQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLT 236
Query: 505 TGA 507
A
Sbjct: 237 VTA 239
>gi|57242755 calsyntenin 1 isoform 2 [Homo sapiens]
Length = 971
Score = 29.3 bits (64), Expect = 10.0
Identities = 15/63 (23%), Positives = 29/63 (46%)
Query: 445 KCHDPVCKAENFKSDCFPLPAEVCLLFLFKEEEEFTTDEADETRSNETQNPHKPSPSRLS 504
K +D + + E +DC P +++C + + FT D+ ++ E N K +L+
Sbjct: 167 KQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLT 226
Query: 505 TGA 507
A
Sbjct: 227 VTA 229
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,442,851
Number of Sequences: 37866
Number of extensions: 1057033
Number of successful extensions: 2714
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2698
Number of HSP's gapped (non-prelim): 27
length of query: 560
length of database: 18,247,518
effective HSP length: 107
effective length of query: 453
effective length of database: 14,195,856
effective search space: 6430722768
effective search space used: 6430722768
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.