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Search of human proteins with 22749359
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22749359 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 3 [Homo sapiens]
(451 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22749359 phosphatidylinositol-3-phosphate 5-kinase type III i... 917 0.0
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 694 0.0
gi|189571664 DEP domain containing 6 [Homo sapiens] 50 4e-06
gi|155030206 Rap guanine nucleotide exchange factor (GEF) 4 isof... 48 2e-05
gi|155030204 Rap guanine nucleotide exchange factor (GEF) 4 isof... 48 2e-05
gi|47578117 DEP domain containing 2 isoform b [Homo sapiens] 48 2e-05
gi|47578115 DEP domain containing 2 isoform a [Homo sapiens] 48 2e-05
gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent R... 46 8e-05
gi|74271832 G protein-coupled receptor 155 isoform 9 [Homo sapiens] 46 8e-05
gi|74271834 G protein-coupled receptor 155 isoform 10 [Homo sapi... 46 8e-05
gi|156627563 regulator of G-protein signaling 7 [Homo sapiens] 39 0.010
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 37 0.048
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 36 0.082
gi|31742476 regulator of G-protein signalling 6 [Homo sapiens] 36 0.082
gi|209862859 DEP domain containing 5 isoform 3 [Homo sapiens] 35 0.11
gi|116256344 novel 58.3 KDA protein isoform 2 [Homo sapiens] 35 0.11
gi|116256342 novel 58.3 KDA protein isoform 1 [Homo sapiens] 35 0.11
gi|7662222 DEP domain containing 5 isoform 1 [Homo sapiens] 35 0.11
gi|41406097 dishevelled 3 [Homo sapiens] 35 0.14
gi|16445033 ACRC protein [Homo sapiens] 35 0.18
gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo ... 35 0.18
gi|166295188 DEP domain containing 1 isoform a [Homo sapiens] 34 0.24
gi|38488716 DEP domain containing 1 isoform b [Homo sapiens] 34 0.24
gi|237858797 lymphocyte antigen 6 complex, locus K isoform 3 [Ho... 34 0.31
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 34 0.31
gi|207113186 MAP kinase-interacting serine/threonine kinase 1 is... 33 0.40
gi|21361101 MAP kinase-interacting serine/threonine kinase 1 iso... 33 0.40
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi... 33 0.53
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 33 0.53
gi|45439359 triple functional domain (PTPRF interacting) [Homo s... 33 0.69
>gi|22749359 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 3 [Homo sapiens]
Length = 451
Score = 917 bits (2370), Expect = 0.0
Identities = 451/451 (100%), Positives = 451/451 (100%)
Query: 1 MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERA 60
MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERA
Sbjct: 1 MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERA 60
Query: 61 EGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALGDLRACTYCRKIA 120
EGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALGDLRACTYCRKIA
Sbjct: 61 EGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALGDLRACTYCRKIA 120
Query: 121 LSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQSLIH 180
LSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQSLIH
Sbjct: 121 LSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQSLIH 180
Query: 181 PDSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQANRTYV 240
PDSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQANRTYV
Sbjct: 181 PDSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQANRTYV 240
Query: 241 RTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIRN 300
RTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIRN
Sbjct: 241 RTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIRN 300
Query: 301 GHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEFSETPSPDSDSVNS 360
GHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEFSETPSPDSDSVNS
Sbjct: 301 GHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEFSETPSPDSDSVNS 360
Query: 361 VEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQSTVDSDSAASISL 420
VEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQSTVDSDSAASISL
Sbjct: 361 VEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQSTVDSDSAASISL 420
Query: 421 NVELDNVNFHIKKPSKYPHVPPHPADQKGRR 451
NVELDNVNFHIKKPSKYPHVPPHPADQKGRR
Sbjct: 421 NVELDNVNFHIKKPSKYPHVPPHPADQKGRR 451
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 694 bits (1791), Expect = 0.0
Identities = 341/341 (100%), Positives = 341/341 (100%)
Query: 108 GDLRACTYCRKIALSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRTPVGSRKASRNI 167
GDLRACTYCRKIALSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRTPVGSRKASRNI
Sbjct: 205 GDLRACTYCRKIALSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRTPVGSRKASRNI 264
Query: 168 FLEDDLAWQSLIHPDSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSY 227
FLEDDLAWQSLIHPDSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSY
Sbjct: 265 FLEDDLAWQSLIHPDSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSY 324
Query: 228 ETSVSPQANRTYVRTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNC 287
ETSVSPQANRTYVRTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNC
Sbjct: 325 ETSVSPQANRTYVRTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNC 384
Query: 288 IVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEF 347
IVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEF
Sbjct: 385 IVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEF 444
Query: 348 SETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQ 407
SETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQ
Sbjct: 445 SETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQ 504
Query: 408 STVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPHPADQK 448
STVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPHPADQK
Sbjct: 505 STVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPHPADQK 545
Score = 221 bits (564), Expect = 8e-58
Identities = 108/111 (97%), Positives = 108/111 (97%)
Query: 1 MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERA 60
MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERA
Sbjct: 1 MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERA 60
Query: 61 EGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALGDLR 111
EGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSAL R
Sbjct: 61 EGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALDTRR 111
>gi|189571664 DEP domain containing 6 [Homo sapiens]
Length = 409
Score = 50.1 bits (118), Expect = 4e-06
Identities = 24/66 (36%), Positives = 37/66 (56%)
Query: 275 QDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRD 334
+D R+ L+T+PNC V KEL++WLI + + R AI + Q + D + V + F+D
Sbjct: 51 KDRRHHLKTYPNCFVAKELIDWLIEHKEASDRETAIKLMQKLADRGIIHHVCDEHKEFKD 110
Query: 335 EYALYR 340
YR
Sbjct: 111 VKLFYR 116
>gi|155030206 Rap guanine nucleotide exchange factor (GEF) 4 isoform
b [Homo sapiens]
Length = 867
Score = 47.8 bits (112), Expect = 2e-05
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 13/143 (9%)
Query: 219 SGSPMVPSYETS--VSPQANRTYVRTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQD 276
S + +P E + + P T T KIL L++ H +D
Sbjct: 25 SNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHM----IRD 80
Query: 277 HRYWLRTHPNCIVGKELVNWLIRNGH-IATRAQAIAIGQAMVDGRWLDCV--SHHDQLFR 333
+Y L+T+ C VG ELV+W+++ + +R QA+ + Q +++ L+ V HH F+
Sbjct: 81 RKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHH---FQ 137
Query: 334 DEYALYRPLQSTEFSETPSPDSD 356
D+Y YR L E + P P +
Sbjct: 138 DKYLFYRFLDD-EHEDAPLPTEE 159
>gi|155030204 Rap guanine nucleotide exchange factor (GEF) 4 isoform
a [Homo sapiens]
Length = 1011
Score = 47.8 bits (112), Expect = 2e-05
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 13/143 (9%)
Query: 219 SGSPMVPSYETS--VSPQANRTYVRTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQD 276
S + +P E + + P T T KIL L++ H +D
Sbjct: 169 SNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHM----IRD 224
Query: 277 HRYWLRTHPNCIVGKELVNWLIRNGH-IATRAQAIAIGQAMVDGRWLDCV--SHHDQLFR 333
+Y L+T+ C VG ELV+W+++ + +R QA+ + Q +++ L+ V HH F+
Sbjct: 225 RKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHH---FQ 281
Query: 334 DEYALYRPLQSTEFSETPSPDSD 356
D+Y YR L E + P P +
Sbjct: 282 DKYLFYRFLDD-EHEDAPLPTEE 303
>gi|47578117 DEP domain containing 2 isoform b [Homo sapiens]
Length = 979
Score = 47.8 bits (112), Expect = 2e-05
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 255 SVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQ 314
S Q + L+K +C G +D + L T P C +G E V+WL+ G I + + +GQ
Sbjct: 379 SEQGEKLYKMMCRQ--GNLIKDRKRKLTTFPKCFLGSEFVSWLLEIGEIHRPEEGVHLGQ 436
Query: 315 AMVDGRWLDCVSHHDQLFRDEYALYR 340
A+++ + V+ Q F+ E LYR
Sbjct: 437 ALLENGIIHHVTDKHQ-FKPEQMLYR 461
Score = 42.7 bits (99), Expect = 7e-04
Identities = 21/66 (31%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 275 QDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRD 334
+D Y LRT+ + ++ +L++WLI G TR +A+ G + D ++ V + F+D
Sbjct: 498 RDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFGVGLCDNGFMHHVLEKSE-FKD 556
Query: 335 EYALYR 340
E L+R
Sbjct: 557 EPLLFR 562
>gi|47578115 DEP domain containing 2 isoform a [Homo sapiens]
Length = 1606
Score = 47.8 bits (112), Expect = 2e-05
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 255 SVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQ 314
S Q + L+K +C G +D + L T P C +G E V+WL+ G I + + +GQ
Sbjct: 379 SEQGEKLYKMMCRQ--GNLIKDRKRKLTTFPKCFLGSEFVSWLLEIGEIHRPEEGVHLGQ 436
Query: 315 AMVDGRWLDCVSHHDQLFRDEYALYR 340
A+++ + V+ Q F+ E LYR
Sbjct: 437 ALLENGIIHHVTDKHQ-FKPEQMLYR 461
Score = 42.7 bits (99), Expect = 7e-04
Identities = 21/66 (31%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 275 QDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRD 334
+D Y LRT+ + ++ +L++WLI G TR +A+ G + D ++ V + F+D
Sbjct: 498 RDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFGVGLCDNGFMHHVLEKSE-FKD 556
Query: 335 EYALYR 340
E L+R
Sbjct: 557 EPLLFR 562
>gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac
exchange factor 1 [Homo sapiens]
Length = 1659
Score = 45.8 bits (107), Expect = 8e-05
Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 275 QDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRD 334
+D R L T P C +G E V WL+ G I+ + + +GQA+++ + VS Q F++
Sbjct: 429 KDRRRKLSTVPKCFLGNEFVAWLLEIGEISKTEEGVNLGQALLENGIIHHVSDKHQ-FKN 487
Query: 335 EYALYR 340
E +YR
Sbjct: 488 EQVMYR 493
Score = 44.7 bits (104), Expect = 2e-04
Identities = 25/85 (29%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
Query: 275 QDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRD 334
+D Y L+T+ + + G +LV+WL+ G TR +A+A+G + + ++ V + FRD
Sbjct: 530 KDRDYHLKTYKSVLPGSKLVDWLLAQGDCQTREEAVALGVGLCNNGFMHHVLEKSE-FRD 588
Query: 335 EYALYRPLQSTEFSETPSPDSDSVN 359
E +R E T S + N
Sbjct: 589 ESQYFRFHADEEMEGTSSKNKQLRN 613
>gi|74271832 G protein-coupled receptor 155 isoform 9 [Homo sapiens]
Length = 870
Score = 45.8 bits (107), Expect = 8e-05
Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 6/99 (6%)
Query: 275 QDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRD 334
++ R +T G +LV+WLI G + R +A+ G +V G + +++ + FRD
Sbjct: 768 KERRCGAKTSAGTFCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYE-FRD 826
Query: 335 EYALYRPLQSTEFSETPSPDSDSV-----NSVEGHSEPS 368
EY YR LQ + P+ +++++ +E S PS
Sbjct: 827 EYLFYRFLQKSPEQSPPAINANTLQQERYKEIEHSSPPS 865
>gi|74271834 G protein-coupled receptor 155 isoform 10 [Homo
sapiens]
Length = 870
Score = 45.8 bits (107), Expect = 8e-05
Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 6/99 (6%)
Query: 275 QDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRD 334
++ R +T G +LV+WLI G + R +A+ G +V G + +++ + FRD
Sbjct: 768 KERRCGAKTSAGTFCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYE-FRD 826
Query: 335 EYALYRPLQSTEFSETPSPDSDSV-----NSVEGHSEPS 368
EY YR LQ + P+ +++++ +E S PS
Sbjct: 827 EYLFYRFLQKSPEQSPPAINANTLQQERYKEIEHSSPPS 865
>gi|156627563 regulator of G-protein signaling 7 [Homo sapiens]
Length = 487
Score = 38.9 bits (89), Expect = 0.010
Identities = 24/107 (22%), Positives = 48/107 (44%)
Query: 234 QANRTYVRTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNCIVGKEL 293
Q N + DE +L +++D+ ++ +G+ + + +L P+ G ++
Sbjct: 3 QGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDI 62
Query: 294 VNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYR 340
V WLI+N I +A+ +G M + +S H +D+ YR
Sbjct: 63 VQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYR 109
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 36.6 bits (83), Expect = 0.048
Identities = 56/229 (24%), Positives = 89/229 (38%), Gaps = 27/229 (11%)
Query: 7 TSPTLDSANDLPRSPTSPSHLTHFKPLTPDQ----DEPPFKSAYSSFVNLFRFNKERAEG 62
T+P L + S + S T P TP +EP + + + F ++
Sbjct: 2375 TTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTS 2434
Query: 63 GQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALGDLRACTYCRKIALS 122
G E+ S P P+ TQ+ T L EE S+ G LS
Sbjct: 2435 GLTEE-----STAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT-------TLS 2482
Query: 123 YAHSTDSNSIGEDL-NALSDSACSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQSLIHP 181
A ST S +GE + LS S+ + L P P TP S K++ + S P
Sbjct: 2483 PARSTTSGLVGESTPSRLSPSSTETTTL-PGSPTTPSLSEKST--------TFYTSPRSP 2533
Query: 182 DSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETS 230
D++ +P +T V E++ S ++ S T D + +P + + T+
Sbjct: 2534 DATLSPATTTSSGVSEESSTSHSQPGSTHTTAFP-DSTTTPGLSRHSTT 2581
Score = 35.8 bits (81), Expect = 0.082
Identities = 52/219 (23%), Positives = 82/219 (37%), Gaps = 22/219 (10%)
Query: 19 RSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERAEGGQGEQQPLSGSWTSPQ 78
R T + H + +EP + + + F ++ G E+ S P
Sbjct: 1308 RGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE-----STAFPG 1362
Query: 79 LPSRTQSVRSPTPYKKQLNEELQRRSSALGDLRACTYCRKIALSYAHSTDSNSIGEDL-N 137
P+ TQ+ T L EE S+ G LS A ST S +GE +
Sbjct: 1363 SPASTQTGLPATLTTADLGEESTTFPSSSGSTGT-------KLSPARSTTSGLVGESTPS 1415
Query: 138 ALSDSACSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQSLIHPDSSNTPLSTRLVSVQE 197
LS S+ + L P P TP S K++ + S PD++ +P +T V E
Sbjct: 1416 RLSPSSTETTTL-PGSPTTPSLSEKST--------TFYTSPRSPDATLSPATTTSSGVSE 1466
Query: 198 DAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQAN 236
++ S ++ S T + S + TS S Q +
Sbjct: 1467 ESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGS 1505
Score = 34.7 bits (78), Expect = 0.18
Identities = 55/231 (23%), Positives = 86/231 (37%), Gaps = 32/231 (13%)
Query: 7 TSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERAEGGQGE 66
+SP PRS T+ ++EP + + + F ++ G E
Sbjct: 3946 SSPGSTETTVFPRSTTTSVR----------REEPTTFHSRPASTHTTLFTEDSTTSGLTE 3995
Query: 67 QQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALGDLRACTYCRKIALSYAHS 126
+ S P P+ TQ+ T L EE S+ G LS A S
Sbjct: 3996 E-----STAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT-------KLSPARS 4043
Query: 127 TDSNSIGEDL-NALSDSACSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQSLIHPDSSN 185
T S +GE + LS S+ + L P P TP S K++ + S PD++
Sbjct: 4044 TTSGLVGESTPSRLSPSSTETTTL-PGSPTTPSLSEKST--------TFYTSPRSPDATL 4094
Query: 186 TPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQAN 236
+P +T V E++ S ++ S T + S + TS S Q +
Sbjct: 4095 SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGS 4145
Score = 33.9 bits (76), Expect = 0.31
Identities = 46/172 (26%), Positives = 65/172 (37%), Gaps = 19/172 (11%)
Query: 77 PQLPSRTQSVRSPTPYKKQLNEELQRRSSALGDLRACTYCRKIALSYAHSTDSNSIGEDL 136
P P+ TQ+ T L EE S+ G LS A ST S +GE
Sbjct: 2918 PGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT-------TLSPARSTTSGLVGEST 2970
Query: 137 -NALSDSACSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQSLIHPDSSNTPLSTRLVSV 195
+ LS S+ + L P P TP S K++ + S PD++ +P +T V
Sbjct: 2971 PSRLSPSSTETTTL-PGSPTTPSLSEKST--------TFYTSPRSPDATLSPATTTSSGV 3021
Query: 196 QEDAGKSPARNRSASITNL--SLDRSGSPMVPSYETSVSPQANRTYVRTETT 245
E++ S ++ S T S SG P+ S T TT
Sbjct: 3022 SEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTT 3073
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 35.8 bits (81), Expect = 0.082
Identities = 52/219 (23%), Positives = 82/219 (37%), Gaps = 22/219 (10%)
Query: 19 RSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERAEGGQGEQQPLSGSWTSPQ 78
R T + H + +EP + + + F ++ G E+ S P
Sbjct: 795 RGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE-----STAFPG 849
Query: 79 LPSRTQSVRSPTPYKKQLNEELQRRSSALGDLRACTYCRKIALSYAHSTDSNSIGEDL-N 137
P+ TQ+ T L EE S+ G LS A ST S +GE +
Sbjct: 850 SPASTQTGLPATLTTADLGEESTTFPSSSGSTGT-------KLSPARSTTSGLVGESTPS 902
Query: 138 ALSDSACSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQSLIHPDSSNTPLSTRLVSVQE 197
LS S+ + L P P TP S K++ + S PD++ +P +T V E
Sbjct: 903 RLSPSSTETTTL-PGSPTTPSLSEKST--------TFYTSPRSPDATLSPATTTSSGVSE 953
Query: 198 DAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQAN 236
++ S ++ S T + S + TS S Q +
Sbjct: 954 ESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGS 992
>gi|31742476 regulator of G-protein signalling 6 [Homo sapiens]
Length = 472
Score = 35.8 bits (81), Expect = 0.082
Identities = 17/72 (23%), Positives = 36/72 (50%)
Query: 269 SSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHH 328
+ G+ + + +L P+ + G ++V WL++N I +AI +G + ++ +S H
Sbjct: 41 TGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDH 100
Query: 329 DQLFRDEYALYR 340
+D+ YR
Sbjct: 101 VLTMKDDGTFYR 112
>gi|209862859 DEP domain containing 5 isoform 3 [Homo sapiens]
Length = 1594
Score = 35.4 bits (80), Expect = 0.11
Identities = 31/141 (21%), Positives = 60/141 (42%), Gaps = 25/141 (17%)
Query: 201 KSPARNRSASITNLSLDRSGSPMVPSYETSVSPQANRTYVRTETTEDERKI--------- 251
+SP SA +S+D++ +PM+ + + ++T + + I
Sbjct: 1089 RSPRTASSAFYPQVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTN 1148
Query: 252 -------------LLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLI 298
L S L ++ + + H S+G++ + L P C + E+V+WL+
Sbjct: 1149 SSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLS--PYCFISAEVVHWLV 1206
Query: 299 RNGH-IATRAQAIAIGQAMVD 318
+ I T+A AI I Q M++
Sbjct: 1207 NHVEGIQTQAMAIDIMQKMLE 1227
>gi|116256344 novel 58.3 KDA protein isoform 2 [Homo sapiens]
Length = 502
Score = 35.4 bits (80), Expect = 0.11
Identities = 37/157 (23%), Positives = 73/157 (46%), Gaps = 14/157 (8%)
Query: 261 LWKKICHH-SSGMEFQDHRYWLRTHPNCIVGKELV----NWLIRNGHIA----TRAQAIA 311
+W I + + +E + R+ L+ H +C VG E V + LI+N + RA+ +
Sbjct: 29 VWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGDVDIPRAKVVR 88
Query: 312 IGQAMVDGRWLDCVSHHDQLF-RDEYALYRPLQSTEFSETPSPDSDSVNSVEGH-SEPSW 369
+ QA++D + + V ++F +D+ + + + T P+ DS E P+
Sbjct: 89 VCQALMDYKVFEAVP--TKVFGKDKKPTFEDSSCSLYRFTTIPNQDSQLGKENKLYSPAR 146
Query: 370 FKDIKFDDSDTEQIA-EEGDDNLANSASPSKRTSVSS 405
+ D F SD + E+ +NL+ + S ++S+
Sbjct: 147 YADALFKSSDIRSASLEDLWENLSLKPANSPHVNISA 183
>gi|116256342 novel 58.3 KDA protein isoform 1 [Homo sapiens]
Length = 511
Score = 35.4 bits (80), Expect = 0.11
Identities = 37/157 (23%), Positives = 73/157 (46%), Gaps = 14/157 (8%)
Query: 261 LWKKICHH-SSGMEFQDHRYWLRTHPNCIVGKELV----NWLIRNGHIA----TRAQAIA 311
+W I + + +E + R+ L+ H +C VG E V + LI+N + RA+ +
Sbjct: 38 VWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGDVDIPRAKVVR 97
Query: 312 IGQAMVDGRWLDCVSHHDQLF-RDEYALYRPLQSTEFSETPSPDSDSVNSVEGH-SEPSW 369
+ QA++D + + V ++F +D+ + + + T P+ DS E P+
Sbjct: 98 VCQALMDYKVFEAVP--TKVFGKDKKPTFEDSSCSLYRFTTIPNQDSQLGKENKLYSPAR 155
Query: 370 FKDIKFDDSDTEQIA-EEGDDNLANSASPSKRTSVSS 405
+ D F SD + E+ +NL+ + S ++S+
Sbjct: 156 YADALFKSSDIRSASLEDLWENLSLKPANSPHVNISA 192
>gi|7662222 DEP domain containing 5 isoform 1 [Homo sapiens]
Length = 1572
Score = 35.4 bits (80), Expect = 0.11
Identities = 33/133 (24%), Positives = 61/133 (45%), Gaps = 6/133 (4%)
Query: 189 STRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQANRTYVRTETTEDE 248
S R VSV + A T S+DR S + + ++ Q + ++++ +
Sbjct: 1076 SPRKVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQ-NIGEQGYSSTNSSDSSSQQ 1134
Query: 249 --RKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGH-IAT 305
L S L ++ + + H S+G++ + L P C + E+V+WL+ + I T
Sbjct: 1135 LVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLS--PYCFISAEVVHWLVNHVEGIQT 1192
Query: 306 RAQAIAIGQAMVD 318
+A AI I Q M++
Sbjct: 1193 QAMAIDIMQKMLE 1205
>gi|41406097 dishevelled 3 [Homo sapiens]
Length = 716
Score = 35.0 bits (79), Expect = 0.14
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 223 MVPSYETSVSPQANRTYVRTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLR 282
M PS T S ++ T +T + L + + K + SG+E +D R WL+
Sbjct: 377 MSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMASPESGLEVRD-RMWLK 435
Query: 283 -THPNCIVGKELVNWLIRN 300
T PN +G ++V+WL N
Sbjct: 436 ITIPNAFIGSDVVDWLYHN 454
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 34.7 bits (78), Expect = 0.18
Identities = 20/74 (27%), Positives = 33/74 (44%)
Query: 341 PLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKR 400
P +++ SE P +SD + + +S+ S D DDS + + DDN +S P +
Sbjct: 159 PDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDK 218
Query: 401 TSVSSFQSTVDSDS 414
+ S DS
Sbjct: 219 SDDSDVPDDSSDDS 232
Score = 32.3 bits (72), Expect = 0.90
Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 4/78 (5%)
Query: 341 PLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDS----DTEQIAEEGDDNLANSAS 396
P S++ SE P SD + + S+ S D DDS D+ +E DD+ +S +
Sbjct: 245 PDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEA 304
Query: 397 PSKRTSVSSFQSTVDSDS 414
P ++ S DS
Sbjct: 305 PDDKSDDSDVPEDKSDDS 322
Score = 30.8 bits (68), Expect = 2.6
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 6/85 (7%)
Query: 341 PLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKR 400
P +++ SE P +SD + + +S+ S D DDS E DDN +S P
Sbjct: 139 PDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDS------EAPDDNSDDSDVPDDN 192
Query: 401 TSVSSFQSTVDSDSAASISLNVELD 425
+ SS ++ DS S +V D
Sbjct: 193 SDDSSDDNSDDSSDDNSDDSDVPDD 217
Score = 30.8 bits (68), Expect = 2.6
Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 2/75 (2%)
Query: 341 PLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDT--EQIAEEGDDNLANSASPS 398
P +++ SE P +SD + + +S+ S D DDSD + + DDN +S+ +
Sbjct: 149 PDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDN 208
Query: 399 KRTSVSSFQSTVDSD 413
S + DSD
Sbjct: 209 SDDSDVPDDKSDDSD 223
Score = 30.4 bits (67), Expect = 3.4
Identities = 19/75 (25%), Positives = 34/75 (45%)
Query: 341 PLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKR 400
P S++ S+ P SD + + S+ S D DDS+ + + + +S+ S+
Sbjct: 225 PDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEA 284
Query: 401 TSVSSFQSTVDSDSA 415
+ SS S DS+
Sbjct: 285 SDDSSDDSEASDDSS 299
Score = 30.0 bits (66), Expect = 4.5
Identities = 20/64 (31%), Positives = 31/64 (48%)
Query: 352 SPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQSTVD 411
S D +S +S + +S+ S D K DDSD + + D +S+ S+ SS S
Sbjct: 196 SSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAP 255
Query: 412 SDSA 415
DS+
Sbjct: 256 DDSS 259
Score = 30.0 bits (66), Expect = 4.5
Identities = 19/75 (25%), Positives = 33/75 (44%)
Query: 341 PLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKR 400
P S++ SE P SD + + S+ S D DDS+ + + + +S+ S+
Sbjct: 235 PDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEA 294
Query: 401 TSVSSFQSTVDSDSA 415
+ SS S D +
Sbjct: 295 SDDSSDDSEAPDDKS 309
Score = 29.6 bits (65), Expect = 5.8
Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 4/81 (4%)
Query: 341 PLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDS----DTEQIAEEGDDNLANSAS 396
P ++ S+ P SD + + S+ S D DDS D+ +E DD+ +S +
Sbjct: 215 PDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEA 274
Query: 397 PSKRTSVSSFQSTVDSDSAAS 417
P + S DS AS
Sbjct: 275 PDDSSDDSEASDDSSDDSEAS 295
>gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo
sapiens]
Length = 782
Score = 34.7 bits (78), Expect = 0.18
Identities = 61/234 (26%), Positives = 87/234 (37%), Gaps = 37/234 (15%)
Query: 18 PRSPTSPSHLTHFKPLTPDQ-DEPPFKSAYS-----SFVNLFRFNKERAEG--GQGEQQP 69
PR+ S H P +P Q +E PF + S L + AEG G G Q+
Sbjct: 391 PRTLNGVSSPPHPSPKSPVQLEEAPFSRRFGLLKTGSSGALGPPERRTAEGAPGAGLQRS 450
Query: 70 LSGSW---TSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALGDLRACTYCRKIALSYAHS 126
S SW TS Q + +PTP K S L ++ C + +S
Sbjct: 451 ASSSWLEGTSTQAKELRLARITPTPSPKL------PEPSVLSEVTKPPPCLE------NS 498
Query: 127 TDSNSIGEDLNALSDSACSVSVLDPSEPRT-------PVGSRKASRNIFLEDDLAWQSLI 179
+ + I E + + + S P++ R PV ++ L QS
Sbjct: 499 SPPSRIPEPESPAKPNVPTASTAPPADSRDRRRSYQMPVRDEESESQRKARSRLMRQSR- 557
Query: 180 HPDSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSP 233
S+ T L ++ AGK+P + A SLD S P VP E S SP
Sbjct: 558 --RSTQGVTLTDLKEAEKAAGKAPESEKPAQ----SLDPSRRPRVPGVENSDSP 605
>gi|166295188 DEP domain containing 1 isoform a [Homo sapiens]
Length = 811
Score = 34.3 bits (77), Expect = 0.24
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 17/90 (18%)
Query: 261 LWKKIC-HHSSGMEFQDHRYWLRTHPNCIVGKELVNW---LIRN----GHIATRAQAIAI 312
LW ++ +GM + HR + + NC E V+W L+RN G TR Q I +
Sbjct: 16 LWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNNSNFGPEVTRQQTIQL 75
Query: 313 GQAM--------VDGRW-LDCVSHHDQLFR 333
+ + GRW + V ++QLFR
Sbjct: 76 LRKFLKNHVIEDIKGRWGSENVDDNNQLFR 105
>gi|38488716 DEP domain containing 1 isoform b [Homo sapiens]
Length = 527
Score = 34.3 bits (77), Expect = 0.24
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 17/90 (18%)
Query: 261 LWKKIC-HHSSGMEFQDHRYWLRTHPNCIVGKELVNW---LIRN----GHIATRAQAIAI 312
LW ++ +GM + HR + + NC E V+W L+RN G TR Q I +
Sbjct: 16 LWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNNSNFGPEVTRQQTIQL 75
Query: 313 GQAM--------VDGRW-LDCVSHHDQLFR 333
+ + GRW + V ++QLFR
Sbjct: 76 LRKFLKNHVIEDIKGRWGSENVDDNNQLFR 105
>gi|237858797 lymphocyte antigen 6 complex, locus K isoform 3 [Homo
sapiens]
Length = 105
Score = 33.9 bits (76), Expect = 0.31
Identities = 15/56 (26%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 261 LWKKICHHSSGMEFQDHRYWLRTHPNCIVGK-ELVNWLIRNGHIATRAQAIAIGQA 315
+W +C + E Q+ R T P C++ ++ WL +G R +A++ G+A
Sbjct: 41 VWCHVCERENTFECQNPRRCKWTEPYCVIAAVTVLRWLCSDGETQARGEAVSPGRA 96
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 33.9 bits (76), Expect = 0.31
Identities = 50/262 (19%), Positives = 86/262 (32%), Gaps = 46/262 (17%)
Query: 180 HPDSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQANRTY 239
+P S ++ + E++ SP + ++ + G+P S + N+
Sbjct: 109 YPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSAS---KTKDKVNKRN 165
Query: 240 VRTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIR 299
R ET I D+ ++K+L + + + +D W H C
Sbjct: 166 ERGETRLHRAAIRGDARRIKELISE----GADVNVKDFAGWTALHEAC-----------N 210
Query: 300 NGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYR--------PLQSTEFSETP 351
G+ Q +A G + D HD Y + + P QS ETP
Sbjct: 211 RGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETP 270
Query: 352 --------------------SPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNL 391
S + S S E PS+ D ++T+ E+G +
Sbjct: 271 LKVANSPTMVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHK 330
Query: 392 ANSASPSKRTSVSSFQSTVDSD 413
A + P K T+ + D D
Sbjct: 331 AKNPEPQKATAPVKDEYEFDED 352
>gi|207113186 MAP kinase-interacting serine/threonine kinase 1
isoform 3 [Homo sapiens]
Length = 424
Score = 33.5 bits (75), Expect = 0.40
Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 19/124 (15%)
Query: 35 PDQDEPPFKSAYSSFVN--LFRFNKERAEGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPY 92
PD+D S ++ L R K+R Q Q P W Q P + PTP
Sbjct: 295 PDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHP----WVQGQAPEKGL----PTP- 345
Query: 93 KKQLNEELQRRSSALGDLRACTYCRKIALSYAHST-DSNSIGEDLNALSDSACSVSVLDP 151
+ LQR SS + DL IAL+ S + N + E+ AL+D CS+ + P
Sbjct: 346 -----QVLQRNSSTM-DLTLFA-AEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPP 398
Query: 152 SEPR 155
+ R
Sbjct: 399 CKSR 402
>gi|21361101 MAP kinase-interacting serine/threonine kinase 1
isoform 1 [Homo sapiens]
Length = 465
Score = 33.5 bits (75), Expect = 0.40
Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 19/124 (15%)
Query: 35 PDQDEPPFKSAYSSFVN--LFRFNKERAEGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPY 92
PD+D S ++ L R K+R Q Q P W Q P + PTP
Sbjct: 336 PDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHP----WVQGQAPEKGL----PTP- 386
Query: 93 KKQLNEELQRRSSALGDLRACTYCRKIALSYAHST-DSNSIGEDLNALSDSACSVSVLDP 151
+ LQR SS + DL IAL+ S + N + E+ AL+D CS+ + P
Sbjct: 387 -----QVLQRNSSTM-DLTLFA-AEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPP 439
Query: 152 SEPR 155
+ R
Sbjct: 440 CKSR 443
>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 490
Score = 33.1 bits (74), Expect = 0.53
Identities = 41/125 (32%), Positives = 51/125 (40%), Gaps = 16/125 (12%)
Query: 325 VSHHDQLFRDEYAL---YRPLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTE 381
VS H L Y+L +RPL S S PSP SD + + G PS D+ SD
Sbjct: 86 VSPHCPLVSPHYSLVSPHRPLVSPLLSGVPSPPSDVPSLLSG--VPSLPSDVSSPPSDVP 143
Query: 382 QIAEEGDDNLANSASPSKRTSVSSFQSTVDSDSAASISLNVELDNVNFHIKKPSKYPHVP 441
+ + L S PS + V S S V S + SL L V PS VP
Sbjct: 144 SLLSDVPSLL--SGVPSPPSDVPSPPSDVPSPPSDVPSL---LSGV------PSPPSDVP 192
Query: 442 PHPAD 446
P+D
Sbjct: 193 SPPSD 197
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 33.1 bits (74), Expect = 0.53
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 6/76 (7%)
Query: 344 STEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSV 403
S S++ S DSDS +S + S S + SD+ ++ D + ++ +S SK S
Sbjct: 574 SNSSSDSDSSDSDSSDSSDSDSSDS------SNSSDSSDSSDSSDSSDSSDSSDSKSDSS 627
Query: 404 SSFQSTVDSDSAASIS 419
S + DSDS + S
Sbjct: 628 KSESDSSDSDSKSDSS 643
Score = 31.6 bits (70), Expect = 1.5
Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
Query: 344 STEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSV 403
S++ S + S DSDS NS + S+ S D D SD+ ++ D + ++++S S +S
Sbjct: 715 SSDSSNSNSSDSDSSNSSDS-SDSSNSSDSS-DSSDSSNSSDSSDSSDSSNSSDSSDSSD 772
Query: 404 SSFQSTVDSDSAASISLN 421
SS S + S ++ S N
Sbjct: 773 SSDSSDSSNSSDSNDSSN 790
Score = 30.4 bits (67), Expect = 3.4
Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
Query: 348 SETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRT-SVSSF 406
S S SDS +S + S + D SD++ ++ D N ++S+ S + S +S
Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS 663
Query: 407 QSTVDSDSAASISLNVELDNVN 428
S+ SDS+ S + D+ N
Sbjct: 664 NSSDSSDSSDSSDSSSSSDSSN 685
Score = 30.0 bits (66), Expect = 4.5
Identities = 24/88 (27%), Positives = 36/88 (40%), Gaps = 2/88 (2%)
Query: 348 SETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQ 407
S S SDS +S S S D DSD+ ++ + +NS+ S + S
Sbjct: 557 SSNSSDSSDSSDSDSSDSNSS--SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS 614
Query: 408 STVDSDSAASISLNVELDNVNFHIKKPS 435
+ DS + S S E D+ + K S
Sbjct: 615 DSSDSSDSKSDSSKSESDSSDSDSKSDS 642
Score = 30.0 bits (66), Expect = 4.5
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 6/74 (8%)
Query: 344 STEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSV 403
S++ S++ SDS S S+ D K D SD+ + + DN +S S + S
Sbjct: 613 SSDSSDSSDSKSDSSKSESDSSD----SDSKSDSSDSN--SSDSSDNSDSSDSSNSSNSS 666
Query: 404 SSFQSTVDSDSAAS 417
S S+ SDS++S
Sbjct: 667 DSSDSSDSSDSSSS 680
Score = 29.6 bits (65), Expect = 5.8
Identities = 21/76 (27%), Positives = 33/76 (43%)
Query: 344 STEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSV 403
S + S DSDS NS + + DS + +G D+ +++ S S +S
Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866
Query: 404 SSFQSTVDSDSAASIS 419
SS S + S +S S
Sbjct: 867 SSDSSDSSNSSDSSDS 882
Score = 29.6 bits (65), Expect = 5.8
Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
Query: 348 SETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQ 407
S S SDS +S +G S + + SD+ ++ + + ++ +S S +S SS
Sbjct: 835 SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS 894
Query: 408 S----TVDSDSAASISLNVELDNVN 428
S + DSDS+ S + + D+ N
Sbjct: 895 SDSSNSSDSDSSDSSNSSDSSDSSN 919
Score = 29.3 bits (64), Expect = 7.6
Identities = 22/85 (25%), Positives = 36/85 (42%)
Query: 344 STEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSV 403
S++ + S SDS +S S S D SD+ ++ D +S S S +
Sbjct: 577 SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDS 636
Query: 404 SSFQSTVDSDSAASISLNVELDNVN 428
S + DS+S+ S + D+ N
Sbjct: 637 DSKSDSSDSNSSDSSDNSDSSDSSN 661
Score = 29.3 bits (64), Expect = 7.6
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 1/79 (1%)
Query: 348 SETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQ 407
S S SDS NS E S+ S D DS + D + +NS+ S ++ S
Sbjct: 686 SSDSSDSSDSSNSSES-SDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744
Query: 408 STVDSDSAASISLNVELDN 426
+ DS +++ S + + N
Sbjct: 745 DSSDSSNSSDSSDSSDSSN 763
Score = 28.9 bits (63), Expect = 10.0
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 1/81 (1%)
Query: 348 SETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQ 407
S S SDS +S E + DSD+ + D + ++++S S +S SS
Sbjct: 873 SSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932
Query: 408 STVDSDSAASISLNVELDNVN 428
S SDS+ S + D+ N
Sbjct: 933 SN-SSDSSNSSDSSDSSDSSN 952
>gi|45439359 triple functional domain (PTPRF interacting) [Homo
sapiens]
Length = 3097
Score = 32.7 bits (73), Expect = 0.69
Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 16/101 (15%)
Query: 170 EDDLAWQSLIHPDSSNTPLSTRLVSVQEDAGKS--PARNRSASI--------------TN 213
+D + + L+ P SS TP + LVS E+ KS +R +S+ ++
Sbjct: 1887 DDKASSRLLVRPTSSETPSAAELVSAIEELVKSKMALEDRPSSLLVDQGDSSSPSFNPSD 1946
Query: 214 LSLDRSGSPMVPSYETSVSPQANRTYVRTETTEDERKILLD 254
SL S SP+ E S R YV E E ER + D
Sbjct: 1947 NSLLSSSSPIDEMEERKSSSLKRRHYVLQELVETERDYVRD 1987
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,060,905
Number of Sequences: 37866
Number of extensions: 901532
Number of successful extensions: 3004
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 62
Number of HSP's that attempted gapping in prelim test: 2634
Number of HSP's gapped (non-prelim): 414
length of query: 451
length of database: 18,247,518
effective HSP length: 106
effective length of query: 345
effective length of database: 14,233,722
effective search space: 4910634090
effective search space used: 4910634090
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.