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Search of human proteins with 22748659
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22748659 RNA (guanine-9-) methyltransferase domain
containing 2 [Homo sapiens]
(339 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197927265 RNA (guanine-9-) methyltransferase domain containin... 696 0.0
gi|197927261 RNA (guanine-9-) methyltransferase domain containin... 696 0.0
gi|22748659 RNA (guanine-9-) methyltransferase domain containing... 696 0.0
gi|117606330 RNA (guanine-9-) methyltransferase domain containin... 122 3e-28
gi|117647226 RNA (guanine-9-) methyltransferase domain containin... 72 5e-13
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 51 2e-06
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 51 2e-06
gi|239752449 PREDICTED: hypothetical protein [Homo sapiens] 43 5e-04
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 42 8e-04
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 42 8e-04
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 41 0.001
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 41 0.002
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 41 0.002
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 39 0.005
gi|148746195 trichohyalin [Homo sapiens] 39 0.005
gi|118766347 zinc finger CCCH-type domain containing 6 [Homo sap... 39 0.007
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 39 0.007
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 38 0.011
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 38 0.011
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 37 0.019
gi|157785548 PAS domain containing 1 [Homo sapiens] 37 0.019
gi|18093112 ABT1-associated protein [Homo sapiens] 37 0.019
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 37 0.025
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 37 0.025
gi|52426743 cisplatin resistance-associated overexpressed protei... 37 0.025
gi|19923485 cisplatin resistance-associated overexpressed protei... 37 0.025
gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo sapi... 37 0.033
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 36 0.043
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 36 0.043
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 36 0.043
>gi|197927265 RNA (guanine-9-) methyltransferase domain containing 2
[Homo sapiens]
Length = 339
Score = 696 bits (1795), Expect = 0.0
Identities = 339/339 (100%), Positives = 339/339 (100%)
Query: 1 MSSEMLPAFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQREL 60
MSSEMLPAFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQREL
Sbjct: 1 MSSEMLPAFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQREL 60
Query: 61 RKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKK 120
RKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKK
Sbjct: 61 RKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKK 120
Query: 121 LHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKPEHYSELIKK 180
LHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKPEHYSELIKK
Sbjct: 121 LHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKPEHYSELIKK 180
Query: 181 EDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKM 240
EDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKM
Sbjct: 181 EDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKM 240
Query: 241 NSRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEG 300
NSRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEG
Sbjct: 241 NSRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEG 300
Query: 301 GSDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH 339
GSDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH
Sbjct: 301 GSDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH 339
>gi|197927261 RNA (guanine-9-) methyltransferase domain containing 2
[Homo sapiens]
Length = 339
Score = 696 bits (1795), Expect = 0.0
Identities = 339/339 (100%), Positives = 339/339 (100%)
Query: 1 MSSEMLPAFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQREL 60
MSSEMLPAFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQREL
Sbjct: 1 MSSEMLPAFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQREL 60
Query: 61 RKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKK 120
RKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKK
Sbjct: 61 RKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKK 120
Query: 121 LHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKPEHYSELIKK 180
LHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKPEHYSELIKK
Sbjct: 121 LHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKPEHYSELIKK 180
Query: 181 EDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKM 240
EDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKM
Sbjct: 181 EDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKM 240
Query: 241 NSRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEG 300
NSRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEG
Sbjct: 241 NSRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEG 300
Query: 301 GSDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH 339
GSDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH
Sbjct: 301 GSDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH 339
>gi|22748659 RNA (guanine-9-) methyltransferase domain containing 2
[Homo sapiens]
Length = 339
Score = 696 bits (1795), Expect = 0.0
Identities = 339/339 (100%), Positives = 339/339 (100%)
Query: 1 MSSEMLPAFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQREL 60
MSSEMLPAFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQREL
Sbjct: 1 MSSEMLPAFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQREL 60
Query: 61 RKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKK 120
RKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKK
Sbjct: 61 RKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKK 120
Query: 121 LHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKPEHYSELIKK 180
LHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKPEHYSELIKK
Sbjct: 121 LHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKPEHYSELIKK 180
Query: 181 EDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKM 240
EDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKM
Sbjct: 181 EDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKM 240
Query: 241 NSRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEG 300
NSRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEG
Sbjct: 241 NSRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEG 300
Query: 301 GSDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH 339
GSDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH
Sbjct: 301 GSDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH 339
>gi|117606330 RNA (guanine-9-) methyltransferase domain containing 3
[Homo sapiens]
Length = 316
Score = 122 bits (307), Expect = 3e-28
Identities = 79/246 (32%), Positives = 127/246 (51%), Gaps = 19/246 (7%)
Query: 50 KQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRR--------DVVHSTL 101
KQ+ WE+ +K KRK++++R+K R P KR R + HS
Sbjct: 68 KQRHWEKIVAAKKSKRKQEKERRKANRA--ENPGICPQHSKRFLRALTKDKLLEAKHSGP 125
Query: 102 RLIIDCSFDHLMVLKDIKKLHKQIQRCYAENRRALHPVQFYLTSH--GGQLKKNMDENDK 159
RL ID S H M K++ +L QI+R Y N++A P LT L + +
Sbjct: 126 RLCIDLSMTHYMSKKELSRLAGQIRRLYGSNKKADRPFWICLTGFTTDSPLYEECVRMND 185
Query: 160 GWVNWKDIHIKPEHYSELIKKEDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTY 219
G+ ++ + I E L E L+YLT DS + L+++D +K Y++GGLVD + K +T+
Sbjct: 186 GFSSYL-LDITEEDCFSLFPLETLVYLTPDSEHALEDVDLNKVYILGGLVDESIQKKVTF 244
Query: 220 KQASDYGINHAQLPLGNFVKMNSR------KVLAVNHVFEIILEYLETRDWQEAFFTILP 273
++A +Y + A+LP+ ++ N ++LA+N VF+I+ YLET +W EA +
Sbjct: 245 QKAREYSVKTARLPIQEYMVRNQNGKNYHSEILAINQVFDILSTYLETHNWPEALKKGVS 304
Query: 274 QRKGAV 279
KG +
Sbjct: 305 SGKGYI 310
>gi|117647226 RNA (guanine-9-) methyltransferase domain containing 1
[Homo sapiens]
Length = 403
Score = 72.4 bits (176), Expect = 5e-13
Identities = 59/248 (23%), Positives = 110/248 (44%), Gaps = 27/248 (10%)
Query: 43 RQMKKLIKQKQWEEQRELRKQKRKEKRKRKKL------ERQCQMEPNSDGHDRKRVRRDV 96
RQ+KK +K EE + ++ + E+ K+K +R + G + +
Sbjct: 146 RQIKKEMKAAAREEAKNIKLLETTEEDKQKNFLFLRLWDRNMDIAMGWKGAQAMQFGQP- 204
Query: 97 VHSTLRLIIDCSFDHLMVLKDIKKLHKQIQRCYAENRRALHPVQFYLTS-------HGGQ 149
L+ D ++++ M K+++ Q+ NRR + P Y + H
Sbjct: 205 ------LVFDMAYENYMKRKELQNTVSQLLESEGWNRRNVDPFHIYFCNLKIDGALHREL 258
Query: 150 LKKNMDENDKGWVNWKDIHIKPEHYSELIKKEDLIYLTSDSPNILKELDESKAYVIGGLV 209
+K+ ++ DK + + + + +L K+ +IYLT+DSPN++ K YVIG V
Sbjct: 259 VKRYQEKWDKLLLTSTE-----KSHVDLFPKDSIIYLTADSPNVMTTFRHDKVYVIGSFV 313
Query: 210 DHNHHKGLTYKQASDYGINHAQLPLGNFVKMN-SRKVLAVNHVFEIILEYLETRDWQEAF 268
D + G + +A + LPL +++ K L ++ + I+L +WQEA
Sbjct: 314 DKSMQPGTSLAKAKRLNLATECLPLDKYLQWEIGNKNLTLDQMIRILLCLKNNGNWQEA- 372
Query: 269 FTILPQRK 276
+P+RK
Sbjct: 373 LQFVPKRK 380
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 50.8 bits (120), Expect = 2e-06
Identities = 64/340 (18%), Positives = 142/340 (41%), Gaps = 29/340 (8%)
Query: 11 ETSNVDKKQGINEDQEESQKPR---LGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKE 67
E S ++Q + + Q E+++ + L E + I +++ ++ ++Q ++ELRKQ+ +E
Sbjct: 363 ERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQERE 422
Query: 68 KRKRKKLERQCQMEPNSDGHDRKRVRRDVVHS--TLRLIIDCSFDHLMVLKDIKKLHKQI 125
+R+ + + + + E H+++ +RR + L ++ +L + K+ +
Sbjct: 423 QRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEE 482
Query: 126 QRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKP-EHYSELIKKEDLI 184
QR +R L + YL S Q ++ + + KP HY E + +
Sbjct: 483 QRQAERLQRQLKQERDYLVSLQHQRQEQ-----------RPVEKKPLYHYKEGMSPSEKP 531
Query: 185 YLTSDSPNILKELDESKAYVIGGLVDHNHHKGLT-YKQASDYGINHAQLPLGNFVKMNSR 243
+ P+++ + A V KGL+ +++A + + ++P N +
Sbjct: 532 AWAKEIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSEN 591
Query: 244 KVLAVNHVFEIILEYLETRDW---QEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEG 300
L +E + W +E +PQR ++ A +++ + ++ G
Sbjct: 592 PPLPTR------IEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLG 645
Query: 301 GSDSDSSEEEYSRNE--LDSPHEEKQDKENHTESTVNSLP 338
+S + R E L+SP + + + ST +S P
Sbjct: 646 SQPIRASNPDLRRTEPILESPLQRTSSGSSSSSSTPSSQP 685
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 50.8 bits (120), Expect = 2e-06
Identities = 64/340 (18%), Positives = 142/340 (41%), Gaps = 29/340 (8%)
Query: 11 ETSNVDKKQGINEDQEESQKPR---LGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKE 67
E S ++Q + + Q E+++ + L E + I +++ ++ ++Q ++ELRKQ+ +E
Sbjct: 363 ERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQERE 422
Query: 68 KRKRKKLERQCQMEPNSDGHDRKRVRRDVVHS--TLRLIIDCSFDHLMVLKDIKKLHKQI 125
+R+ + + + + E H+++ +RR + L ++ +L + K+ +
Sbjct: 423 QRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEE 482
Query: 126 QRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKP-EHYSELIKKEDLI 184
QR +R L + YL S Q ++ + + KP HY E + +
Sbjct: 483 QRQAERLQRQLKQERDYLVSLQHQRQEQ-----------RPVEKKPLYHYKEGMSPSEKP 531
Query: 185 YLTSDSPNILKELDESKAYVIGGLVDHNHHKGLT-YKQASDYGINHAQLPLGNFVKMNSR 243
+ P+++ + A V KGL+ +++A + + ++P N +
Sbjct: 532 AWAKEIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSEN 591
Query: 244 KVLAVNHVFEIILEYLETRDW---QEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEG 300
L +E + W +E +PQR ++ A +++ + ++ G
Sbjct: 592 PPLPTR------IEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLG 645
Query: 301 GSDSDSSEEEYSRNE--LDSPHEEKQDKENHTESTVNSLP 338
+S + R E L+SP + + + ST +S P
Sbjct: 646 SQPIRASNPDLRRTEPILESPLQRTSSGSSSSSSTPSSQP 685
>gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 170
Score = 42.7 bits (99), Expect = 5e-04
Identities = 20/64 (31%), Positives = 43/64 (67%)
Query: 23 EDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEP 82
E+++E +K + + + K++ KK K+K+ +++++ RK+KRK KRKRKK ++ + +
Sbjct: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162
Query: 83 NSDG 86
++G
Sbjct: 163 GNEG 166
Score = 38.1 bits (87), Expect = 0.011
Identities = 17/58 (29%), Positives = 40/58 (68%)
Query: 20 GINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQ 77
G+ + +E+ +K + + + K++ KK K+K+ +++++ +K+KRK KRKRK+ +++
Sbjct: 98 GLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKR 155
Score = 36.2 bits (82), Expect = 0.043
Identities = 17/58 (29%), Positives = 37/58 (63%)
Query: 16 DKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKK 73
+KK+ E +++ +K + + + K++ KK K+K+ +++ RK+K+K K+K+KK
Sbjct: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161
Score = 34.7 bits (78), Expect = 0.13
Identities = 14/45 (31%), Positives = 32/45 (71%)
Query: 50 KQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRR 94
K+K+ E++++ +K+K+K+K+K+KK +++ + + RKR R+
Sbjct: 106 KEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRK 150
Score = 33.9 bits (76), Expect = 0.21
Identities = 16/55 (29%), Positives = 38/55 (69%), Gaps = 1/55 (1%)
Query: 40 ISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRR 94
+ +R+ KK K+K+ +++++ +K+K+K+K+K+KK +++ + + RKR R+
Sbjct: 99 LPQREEKKE-KEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRK 152
Score = 32.7 bits (73), Expect = 0.48
Identities = 13/53 (24%), Positives = 35/53 (66%)
Query: 42 KRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRR 94
+ + K+ K+K+ +++++ +K+K+K+K+K+KK +++ + RKR ++
Sbjct: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKK 154
Score = 32.7 bits (73), Expect = 0.48
Identities = 15/57 (26%), Positives = 35/57 (61%)
Query: 38 EPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRR 94
E K + KK K+K+ +++++ +K+K+K+K+K+KK ++ + RK+ ++
Sbjct: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160
Score = 31.2 bits (69), Expect = 1.4
Identities = 12/58 (20%), Positives = 40/58 (68%)
Query: 16 DKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKK 73
++K+ +++++ +K + + + K++ KK K+K+ + +R+ +++++K+++K+KK
Sbjct: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 42.0 bits (97), Expect = 8e-04
Identities = 65/338 (19%), Positives = 135/338 (39%), Gaps = 47/338 (13%)
Query: 10 IETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEK- 68
++ +N ++ + + Q E Q+ E + + K++ +QK E++R L +Q+R+EK
Sbjct: 357 LQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQK--EQRRRLEEQQRREKE 414
Query: 69 -RKRKKLERQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQR 127
RK+++ E++ E + R+ RR H ++ K+ + QR
Sbjct: 415 LRKQQEREQRRHYE---EQMRREEERRRAEHE----------------QEYKRKQLEEQR 455
Query: 128 CYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKP-EHYSELIKKEDLIYL 186
+R L + YL S Q ++ + + KP HY E + +
Sbjct: 456 QAERLQRQLKQERDYLVSLQHQRQEQ-----------RPVEKKPLYHYKEGMSPSEKPAW 504
Query: 187 TSDSPNILKELDESKAYVIGGLVDHNHHKGLT-YKQASDYGINHAQLPLGNFVKMNSRKV 245
+ P+++ + A V KGL+ +++A + + ++P N +
Sbjct: 505 AKEIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPP 564
Query: 246 LAVNHVFEIILEYLETRDW---QEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEGGS 302
L +E + W +E +PQR ++ A +++ + ++ G
Sbjct: 565 LPTR------IEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQ 618
Query: 303 DSDSSEEEYSRNE--LDSPHEEKQDKENHTESTVNSLP 338
+S + R E L+SP + + + ST +S P
Sbjct: 619 PIRASNPDLRRTEPILESPLQRTSSGSSSSSSTPSSQP 656
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 42.0 bits (97), Expect = 8e-04
Identities = 65/338 (19%), Positives = 135/338 (39%), Gaps = 47/338 (13%)
Query: 10 IETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEK- 68
++ +N ++ + + Q E Q+ E + + K++ +QK E++R L +Q+R+EK
Sbjct: 357 LQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQK--EQRRRLEEQQRREKE 414
Query: 69 -RKRKKLERQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQR 127
RK+++ E++ E + R+ RR H ++ K+ + QR
Sbjct: 415 LRKQQEREQRRHYE---EQMRREEERRRAEHE----------------QEYKRKQLEEQR 455
Query: 128 CYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKP-EHYSELIKKEDLIYL 186
+R L + YL S Q ++ + + KP HY E + +
Sbjct: 456 QAERLQRQLKQERDYLVSLQHQRQEQ-----------RPVEKKPLYHYKEGMSPSEKPAW 504
Query: 187 TSDSPNILKELDESKAYVIGGLVDHNHHKGLT-YKQASDYGINHAQLPLGNFVKMNSRKV 245
+ P+++ + A V KGL+ +++A + + ++P N +
Sbjct: 505 AKEIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPP 564
Query: 246 LAVNHVFEIILEYLETRDW---QEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEGGS 302
L +E + W +E +PQR ++ A +++ + ++ G
Sbjct: 565 LPTR------IEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQ 618
Query: 303 DSDSSEEEYSRNE--LDSPHEEKQDKENHTESTVNSLP 338
+S + R E L+SP + + + ST +S P
Sbjct: 619 PIRASNPDLRRTEPILESPLQRTSSGSSSSSSTPSSQP 656
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 41.2 bits (95), Expect = 0.001
Identities = 19/73 (26%), Positives = 42/73 (57%)
Query: 23 EDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEP 82
E++EE + R + E +++ KK K+ + +++E ++KRK KRK+KK E + + E
Sbjct: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEE 79
Query: 83 NSDGHDRKRVRRD 95
+ +++ ++
Sbjct: 80 EEEEEEKEEEEKE 92
Score = 38.9 bits (89), Expect = 0.007
Identities = 21/84 (25%), Positives = 46/84 (54%), Gaps = 6/84 (7%)
Query: 11 ETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRK 70
ET ++K+G +++ + ++ E K++ K+ K+K+ EE+ + RK+KRK+K++
Sbjct: 18 ETEEEEEKEGKRKEKRKEKRK------EKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE 71
Query: 71 RKKLERQCQMEPNSDGHDRKRVRR 94
++ E + + E + K R
Sbjct: 72 EEEREEEEEEEEEEKEEEEKEEGR 95
Score = 36.6 bits (83), Expect = 0.033
Identities = 17/67 (25%), Positives = 43/67 (64%)
Query: 11 ETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRK 70
+T +K++ E++++ ++ R + E + + ++ ++K+ EE+ E R++K+K+KR+
Sbjct: 45 KTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRR 104
Query: 71 RKKLERQ 77
RK+ E +
Sbjct: 105 RKEEEEE 111
Score = 35.0 bits (79), Expect = 0.096
Identities = 16/68 (23%), Positives = 40/68 (58%)
Query: 23 EDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEP 82
E+ EE+++ EG +++ +K ++K+ ++ E RK+K +E++KRK+ ++ + E
Sbjct: 14 EETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEE 73
Query: 83 NSDGHDRK 90
+ + +
Sbjct: 74 EREEEEEE 81
Score = 32.7 bits (73), Expect = 0.48
Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRK 72
KK+ ++EE ++ E E R+ KK K+++ EE+ E +K+KR+ K K+K
Sbjct: 69 KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE-KKKKRRRKTKKK 123
Score = 32.3 bits (72), Expect = 0.62
Identities = 15/79 (18%), Positives = 46/79 (58%)
Query: 16 DKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLE 75
+KK+ E ++ +K + + K++ ++ ++++ EE+ E ++++ KE+ +R+K +
Sbjct: 41 EKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK 100
Query: 76 RQCQMEPNSDGHDRKRVRR 94
++ + + + +KR R+
Sbjct: 101 KKRRRKEEEEEKKKKRRRK 119
Score = 32.0 bits (71), Expect = 0.81
Identities = 20/85 (23%), Positives = 46/85 (54%), Gaps = 7/85 (8%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKE-------KR 69
K++ + +E++K + E E KR+ KK ++++ EE+ E +++++E +R
Sbjct: 38 KEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRR 97
Query: 70 KRKKLERQCQMEPNSDGHDRKRVRR 94
K+KK R+ + E R++ ++
Sbjct: 98 KKKKKRRRKEEEEEKKKKRRRKTKK 122
Score = 31.2 bits (69), Expect = 1.4
Identities = 18/70 (25%), Positives = 40/70 (57%), Gaps = 1/70 (1%)
Query: 25 QEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNS 84
+++ +K + E E + + ++ + K+ E+++E RK+K K K+K K+ E++ + E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEK-KKKTKETEKRKEKEEEE 59
Query: 85 DGHDRKRVRR 94
RKR ++
Sbjct: 60 KKRKRKRKKK 69
Score = 28.5 bits (62), Expect = 9.0
Identities = 13/53 (24%), Positives = 34/53 (64%)
Query: 16 DKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEK 68
++++ E++EE ++ E E +++ KK ++++ EE+++ R++K K+K
Sbjct: 71 EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 40.8 bits (94), Expect = 0.002
Identities = 33/161 (20%), Positives = 77/161 (47%), Gaps = 5/161 (3%)
Query: 11 ETSNVDKKQGINEDQEESQKPR---LGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKE 67
E S ++Q + + Q E+++ + L E + I +++ ++ ++Q ++ELRKQ+ +E
Sbjct: 363 ERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQERE 422
Query: 68 KRKRKKLERQCQMEPNSDGHDRKRVRRDVVHS--TLRLIIDCSFDHLMVLKDIKKLHKQI 125
+R+ + + + + E H+++ +RR + L ++ +L + K+ +
Sbjct: 423 QRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEE 482
Query: 126 QRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKD 166
QR +R L + YL S Q ++ K ++K+
Sbjct: 483 QRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKE 523
>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
sapiens]
Length = 1360
Score = 40.8 bits (94), Expect = 0.002
Identities = 33/161 (20%), Positives = 77/161 (47%), Gaps = 5/161 (3%)
Query: 11 ETSNVDKKQGINEDQEESQKPR---LGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKE 67
E S ++Q + + Q E+++ + L E + I +++ ++ ++Q ++ELRKQ+ +E
Sbjct: 363 ERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQERE 422
Query: 68 KRKRKKLERQCQMEPNSDGHDRKRVRRDVVHS--TLRLIIDCSFDHLMVLKDIKKLHKQI 125
+R+ + + + + E H+++ +RR + L ++ +L + K+ +
Sbjct: 423 QRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEE 482
Query: 126 QRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKD 166
QR +R L + YL S Q ++ K ++K+
Sbjct: 483 QRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKE 523
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 39.3 bits (90), Expect = 0.005
Identities = 19/69 (27%), Positives = 42/69 (60%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLER 76
K++ +E +K R E E +R K+ K+++ +E+RE +K+++KE+RK+K+ ++
Sbjct: 148 KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207
Query: 77 QCQMEPNSD 85
+ + +D
Sbjct: 208 DRKTDRQTD 216
Score = 38.9 bits (89), Expect = 0.007
Identities = 17/78 (21%), Positives = 46/78 (58%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLER 76
+K+ +++ + +K + + +R+ KK ++K+ E + + R++++++KR++KK +
Sbjct: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
Query: 77 QCQMEPNSDGHDRKRVRR 94
+ + E +RKR +R
Sbjct: 146 ERKREKERGKRERKRKKR 163
Score = 38.9 bits (89), Expect = 0.007
Identities = 25/81 (30%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Query: 17 KKQGINEDQEESQ-KPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRK-RKKL 74
K++G E +++ + K R E + +++ K+ K+++ E +RE + KR+ KRK RKK
Sbjct: 107 KQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKE 166
Query: 75 ERQCQMEPNSDGHDRKRVRRD 95
ER+ + E N ++R R++
Sbjct: 167 EREKKRERNRKERKKERERKE 187
Score = 37.0 bits (84), Expect = 0.025
Identities = 18/84 (21%), Positives = 47/84 (55%)
Query: 12 TSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKR 71
T +++ ++E+ ++ R E K++ KK K+++ +E+ RK++ K++++R
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Query: 72 KKLERQCQMEPNSDGHDRKRVRRD 95
++ ER+ + + ++R RR+
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRE 113
Score = 36.2 bits (82), Expect = 0.043
Identities = 24/91 (26%), Positives = 49/91 (53%), Gaps = 17/91 (18%)
Query: 16 DKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRK----- 70
++K+ + +++ +K R E +R+ K+ ++KQ +E+RE ++KRK+++K
Sbjct: 53 ERKRERGKKEKKKRKKR-----ERGKERERKRKEREKQRKERREKERRKRKKEKKKRERK 107
Query: 71 -------RKKLERQCQMEPNSDGHDRKRVRR 94
+KK ER+ + N +RKR +R
Sbjct: 108 QRGRRERKKKKERKERERENKQRRERKRKKR 138
Score = 34.7 bits (78), Expect = 0.13
Identities = 16/58 (27%), Positives = 38/58 (65%)
Query: 16 DKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKK 73
+K++G E + + +K E ++++ KK ++K+ E+++ RK++R++K++RKK
Sbjct: 150 EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207
Score = 33.9 bits (76), Expect = 0.21
Identities = 17/60 (28%), Positives = 39/60 (65%), Gaps = 1/60 (1%)
Query: 37 CEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSD-GHDRKRVRRD 95
C ISK ++ ++K+ +RE RK++R+++RKR++ +++ + + G +R+R R++
Sbjct: 22 CSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKE 81
Score = 33.5 bits (75), Expect = 0.28
Identities = 17/79 (21%), Positives = 46/79 (58%)
Query: 16 DKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLE 75
++++ E ++E ++ R + + KR+ K ++K+ E +++ ++++ KE+RKRKK +
Sbjct: 42 EREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEK 101
Query: 76 RQCQMEPNSDGHDRKRVRR 94
++ + + +K+ R
Sbjct: 102 KKRERKQRGRRERKKKKER 120
Score = 33.5 bits (75), Expect = 0.28
Identities = 19/78 (24%), Positives = 40/78 (51%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLER 76
KK+ +++E K R + K++ +K K+++ +RE +++KRK++ + KK ER
Sbjct: 115 KKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRER 174
Query: 77 QCQMEPNSDGHDRKRVRR 94
+ +R R+
Sbjct: 175 NRKERKKERERKERRERK 192
Score = 33.1 bits (74), Expect = 0.36
Identities = 17/84 (20%), Positives = 48/84 (57%)
Query: 11 ETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRK 70
E ++++ E +E+ ++ R E + K++ ++ K+K+ ++RE ++R+E+++
Sbjct: 76 ERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135
Query: 71 RKKLERQCQMEPNSDGHDRKRVRR 94
+K+ +++ + E + KR R+
Sbjct: 136 KKRRKKKRRKERKREKERGKRERK 159
Score = 33.1 bits (74), Expect = 0.36
Identities = 20/98 (20%), Positives = 49/98 (50%), Gaps = 4/98 (4%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLER 76
KK+ E + E ++ + + K + +K ++ + E ++E +++R+E++K +K ER
Sbjct: 140 KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER 199
Query: 77 QCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMV 114
+ + E D ++ R R + + +F+ + V
Sbjct: 200 RKKKERKKD----RKTDRQTDSQVFRPLRESAFNRVTV 233
Score = 32.7 bits (73), Expect = 0.48
Identities = 21/80 (26%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKR--KEKRKRKKL 74
+K+ + + + +K G +++ KK ++K+ E R+ RK++R KE+R+RKK
Sbjct: 135 RKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
Query: 75 ERQCQMEPNSDGHDRKRVRR 94
++ + + DRK R+
Sbjct: 195 RKKERRKKKERKKDRKTDRQ 214
Score = 31.6 bits (70), Expect = 1.1
Identities = 21/82 (25%), Positives = 47/82 (57%), Gaps = 5/82 (6%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKE----KRKRK 72
KK+ E + E+++ R + + K++ K+ ++K+ ++ RK+++KE KR+R
Sbjct: 116 KKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERN 175
Query: 73 KLERQCQMEPNSDGHDRKRVRR 94
+ ER+ + E + +RK+ R+
Sbjct: 176 RKERKKERE-RKERRERKKERK 196
Score = 29.3 bits (64), Expect = 5.3
Identities = 18/87 (20%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Query: 11 ETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRK 70
E N +++ + + + ++ + + + KR+ K+ K+++ EE+ + R++ RKE++K
Sbjct: 124 ERENKQRRERKRKKRRKKKRRKERKREKERGKRERKR--KKRKKEEREKKRERNRKERKK 181
Query: 71 --RKKLERQCQMEPNSDGHDRKRVRRD 95
+K R+ + E + +K ++D
Sbjct: 182 ERERKERRERKKERKKERRKKKERKKD 208
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 39.3 bits (90), Expect = 0.005
Identities = 23/87 (26%), Positives = 50/87 (57%), Gaps = 1/87 (1%)
Query: 17 KKQGINEDQEESQKPR-LGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLE 75
+K+ +EE Q+ R L E E + K + ++L +++Q EEQ++ R ++ ++ R++++ E
Sbjct: 254 RKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE 313
Query: 76 RQCQMEPNSDGHDRKRVRRDVVHSTLR 102
R+ Q E + +R+ + + LR
Sbjct: 314 RREQQEERREQQERREQQEERREQQLR 340
Score = 36.2 bits (82), Expect = 0.043
Identities = 17/74 (22%), Positives = 44/74 (59%), Gaps = 1/74 (1%)
Query: 23 EDQEESQKPRLGEGCEPISKRQMKKLI-KQKQWEEQRELRKQKRKEKRKRKKLERQCQME 81
E+ ++ ++ LGE E ++++++ K+++ +++ E ++ EKR+R++ ERQC+ E
Sbjct: 1054 EELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREE 1113
Query: 82 PNSDGHDRKRVRRD 95
+ + +R +
Sbjct: 1114 EELQQEEEQLLREE 1127
Score = 34.3 bits (77), Expect = 0.16
Identities = 18/79 (22%), Positives = 45/79 (56%), Gaps = 3/79 (3%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLER 76
++Q + +QEE ++ +L E + Q ++++Q EE+RE + ++ ++ R+ ++L R
Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQ---LRREQEEERREQQLRREQQLRREQQLRR 391
Query: 77 QCQMEPNSDGHDRKRVRRD 95
+ Q+ +++RR+
Sbjct: 392 EQQLRREQQLRREQQLRRE 410
Score = 33.9 bits (76), Expect = 0.21
Identities = 16/59 (27%), Positives = 38/59 (64%), Gaps = 2/59 (3%)
Query: 25 QEESQKPRLGEGCEPISKRQMKKLIK--QKQWEEQRELRKQKRKEKRKRKKLERQCQME 81
+E+S++ R P + Q ++ ++ ++Q EQR L +++ KE+R+R++ ER+ +++
Sbjct: 774 EEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQ 832
Score = 33.5 bits (75), Expect = 0.28
Identities = 22/91 (24%), Positives = 51/91 (56%), Gaps = 12/91 (13%)
Query: 17 KKQGINEDQEESQKPRLG--EGCEPISKRQMKKLIKQKQWEEQRE----------LRKQK 64
++Q + +QEE ++ RL E E + +R + +++ EE+RE L +++
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Query: 65 RKEKRKRKKLERQCQMEPNSDGHDRKRVRRD 95
R+++ KR++ ER+ Q+ + ++R++R+
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQRLKRE 593
Score = 33.1 bits (74), Expect = 0.36
Identities = 21/71 (29%), Positives = 42/71 (59%), Gaps = 2/71 (2%)
Query: 25 QEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNS 84
+EE ++ R +P + Q++K +Q EE+ EL++++R EKR+R++ ERQ + E
Sbjct: 879 EEERKRRRHTLYAKPALQEQLRKE-QQLLQEEEEELQREER-EKRRRQEQERQYREEEQL 936
Query: 85 DGHDRKRVRRD 95
+ + +R +
Sbjct: 937 QQEEEQLLREE 947
Score = 33.1 bits (74), Expect = 0.36
Identities = 28/106 (26%), Positives = 53/106 (50%), Gaps = 7/106 (6%)
Query: 25 QEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQ---CQME 81
QEE Q R G + R +K +++Q ++RE ++ R+E+ ++ +LE Q Q +
Sbjct: 1535 QEEQQLRRQERGQQRRQDRD-RKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 82 PNSDGHDRKRVRRDVVHSTLRLIIDCSF---DHLMVLKDIKKLHKQ 124
D +++RR LR D F + L+ ++ ++LH+Q
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQ 1639
Score = 32.7 bits (73), Expect = 0.48
Identities = 17/58 (29%), Positives = 41/58 (70%), Gaps = 2/58 (3%)
Query: 24 DQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQME 81
+QEE ++ RL EP +R+ ++L+K ++ EE+R+ + ++ +++R+ ++L+R+ + E
Sbjct: 611 EQEERREQRLKRE-EPEEERR-QQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666
Score = 32.7 bits (73), Expect = 0.48
Identities = 19/83 (22%), Positives = 46/83 (55%), Gaps = 3/83 (3%)
Query: 16 DKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQ---KRKEKRKRK 72
++++ +D++ QK G EP +R+ ++ K ++ EE ++ +Q + +EKR+R+
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ 1014
Query: 73 KLERQCQMEPNSDGHDRKRVRRD 95
+ ERQ + + + + +R +
Sbjct: 1015 EWERQYRKKDELQQEEEQLLREE 1037
Score = 32.7 bits (73), Expect = 0.48
Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
Query: 10 IETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKR 69
+E V +++ + E+ Q+ R EG + + + + +K + +Q ++RE +Q +++R
Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQERE-EQQLHRQER 1641
Query: 70 KRKKLERQCQMEPNSD----GHDRKRVRRD 95
RK LE + Q+ HDR R R+
Sbjct: 1642 DRKFLEEEPQLRRQEREQQLRHDRDRKFRE 1671
Score = 32.3 bits (72), Expect = 0.62
Identities = 18/73 (24%), Positives = 44/73 (60%), Gaps = 12/73 (16%)
Query: 25 QEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLE--RQCQMEP 82
+EE Q+ RL + ++ +++KQ EE+RE ++++R+++ +R++ E R+ Q+
Sbjct: 292 EEEQQQQRL----------RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Query: 83 NSDGHDRKRVRRD 95
+ +++RR+
Sbjct: 342 EQEERREQQLRRE 354
Score = 32.3 bits (72), Expect = 0.62
Identities = 20/80 (25%), Positives = 48/80 (60%), Gaps = 5/80 (6%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELR-KQKRKEKRKRKKLE 75
++Q E QEE ++ +L E ++Q+++ +Q EE+RE + +++++E+R+ ++L
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRR----EQEEERREQQLRREQEEERREQQLR 378
Query: 76 RQCQMEPNSDGHDRKRVRRD 95
R+ Q+ +++RR+
Sbjct: 379 REQQLRREQQLRREQQLRRE 398
Score = 32.3 bits (72), Expect = 0.62
Identities = 20/90 (22%), Positives = 44/90 (48%), Gaps = 18/90 (20%)
Query: 23 EDQEESQKPRLGEGCEPISKRQMKKLIKQKQWE------------------EQRELRKQK 64
E +EE ++ L E + ++ ++K I + QW+ ++ + R+Q+
Sbjct: 675 EHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQE 734
Query: 65 RKEKRKRKKLERQCQMEPNSDGHDRKRVRR 94
++EKR+R++ E Q Q E + ++ +R
Sbjct: 735 QEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Score = 32.0 bits (71), Expect = 0.81
Identities = 14/78 (17%), Positives = 45/78 (57%), Gaps = 4/78 (5%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQM----KKLIKQKQWEEQRELRKQKRKEKRKRK 72
++Q + +QEE ++ + + + + Q ++L +++Q +++LR++++ + ++
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419
Query: 73 KLERQCQMEPNSDGHDRK 90
+ E+Q + E + H++K
Sbjct: 420 RREQQLRREQEEERHEQK 437
Score = 32.0 bits (71), Expect = 0.81
Identities = 23/86 (26%), Positives = 47/86 (54%), Gaps = 7/86 (8%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQ-----RELRKQKRKEK--R 69
++Q + E++EE Q+ + +RQ ++ + +Q EEQ RE R+++ +E+ R
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYR 961
Query: 70 KRKKLERQCQMEPNSDGHDRKRVRRD 95
K KKL+++ + + R+R R+
Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQERE 987
Score = 32.0 bits (71), Expect = 0.81
Identities = 20/79 (25%), Positives = 45/79 (56%), Gaps = 11/79 (13%)
Query: 23 EDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKR------KEKRKRKKLER 76
E+ ++ ++ L E EP +R+ ++ ++Q E+ EL++++ +EKR+R++LER
Sbjct: 1084 EELQQEEEQLLRE--EPEKRRRQER---ERQCREEEELQQEEEQLLREEREKRRRQELER 1138
Query: 77 QCQMEPNSDGHDRKRVRRD 95
Q + E + + +R +
Sbjct: 1139 QYREEEEVQQEEEQLLREE 1157
Score = 31.6 bits (70), Expect = 1.1
Identities = 19/79 (24%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
Query: 17 KKQGINEDQEESQK-PRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLE 75
++Q + +QEE + + E E + + K+ +K+ Q EE+RE + +E+R+ ++
Sbjct: 443 REQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQER 502
Query: 76 RQCQMEPNSDGHDRKRVRR 94
R+ Q+ + +R++R
Sbjct: 503 REQQLRREQEERREQRLKR 521
Score = 31.6 bits (70), Expect = 1.1
Identities = 21/77 (27%), Positives = 43/77 (55%), Gaps = 13/77 (16%)
Query: 25 QEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKR------KEKRKRKKLERQC 78
QEE Q R E KR++++ +++Q+ E+ EL++++ +E R+R++LERQ
Sbjct: 1028 QEEEQLLR-----EEREKRRLQE--RERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080
Query: 79 QMEPNSDGHDRKRVRRD 95
+ E + + +R +
Sbjct: 1081 RKEEELQQEEEQLLREE 1097
Score = 31.6 bits (70), Expect = 1.1
Identities = 22/77 (28%), Positives = 43/77 (55%), Gaps = 13/77 (16%)
Query: 25 QEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRK------EKRKRKKLERQC 78
QEE Q R E KR+ ++L ++Q+ E+ E+++++ + EKR+R++LERQ
Sbjct: 1118 QEEEQLLR-----EEREKRRRQEL--ERQYREEEEVQQEEEQLLREEPEKRRRQELERQY 1170
Query: 79 QMEPNSDGHDRKRVRRD 95
+ E + + +R +
Sbjct: 1171 REEEELQQEEEQLLREE 1187
Score = 31.2 bits (69), Expect = 1.4
Identities = 20/76 (26%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQ--KRKEKRKRKKL 74
+KQ + DQEE ++ R + E +R+ ++ +Q+ EQ E R+Q KR+E+ +R +
Sbjct: 472 RKQQLKRDQEEERRERWLK-LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Query: 75 ERQCQMEPNSDGHDRK 90
+ + + + +R+
Sbjct: 531 RLRSEQQLRREQEERR 546
Score = 31.2 bits (69), Expect = 1.4
Identities = 15/62 (24%), Positives = 35/62 (56%), Gaps = 3/62 (4%)
Query: 23 EDQEE---SQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQ 79
E+QE+ ++ R E + ++ + +Q+ W+E+ + R+Q+R+ K + + + RQ +
Sbjct: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQK 1890
Query: 80 ME 81
E
Sbjct: 1891 EE 1892
Score = 30.8 bits (68), Expect = 1.8
Identities = 25/82 (30%), Positives = 46/82 (56%), Gaps = 4/82 (4%)
Query: 16 DKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLE 75
++ Q E QEE ++ R E E +RQ ++ +Q+ EQ+ RKQ +E+R+ ++ E
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ--EEERREQQEE 320
Query: 76 RQCQMEPNSDGHDRK--RVRRD 95
R+ Q E +R+ ++RR+
Sbjct: 321 RREQQERREQQEERREQQLRRE 342
Score = 30.8 bits (68), Expect = 1.8
Identities = 15/73 (20%), Positives = 42/73 (57%)
Query: 23 EDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEP 82
E+ ++ ++ L E E ++++++ ++++ +Q E + + +++++R++ ERQ + E
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEE 1203
Query: 83 NSDGHDRKRVRRD 95
RK+ RD
Sbjct: 1204 ELQRQKRKQRYRD 1216
Score = 30.0 bits (66), Expect = 3.1
Identities = 17/79 (21%), Positives = 48/79 (60%), Gaps = 2/79 (2%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLER 76
++Q + +Q+ ++ +L + + + Q ++ +QK +E+RE ++ KR+++ +R L+R
Sbjct: 403 REQQLRREQQLRREQQLRRE-QQLRREQEEERHEQKHEQERRE-QRLKREQEERRDWLKR 460
Query: 77 QCQMEPNSDGHDRKRVRRD 95
+ + E + +++++RD
Sbjct: 461 EEETERHEQERRKQQLKRD 479
Score = 30.0 bits (66), Expect = 3.1
Identities = 18/81 (22%), Positives = 48/81 (59%), Gaps = 9/81 (11%)
Query: 18 KQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKR-KRKKLER 76
+Q + +QEE + E + KR+ +K ++Q++ E++ + +++R+++ KR++ R
Sbjct: 535 EQQLRREQEERR--------EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERR 586
Query: 77 QCQMEPNSDGHDRKRVRRDVV 97
Q +++ + +R++R+ V
Sbjct: 587 QQRLKREQEERLEQRLKREEV 607
Score = 30.0 bits (66), Expect = 3.1
Identities = 26/114 (22%), Positives = 51/114 (44%), Gaps = 12/114 (10%)
Query: 25 QEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRK----RKKLERQCQM 80
QEE Q R +++ ++ +++Q+ E+ EL++QKRK++ + R L+ Q +
Sbjct: 1178 QEEEQLLR--------EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEP 1229
Query: 81 EPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQRCYAENRR 134
E + D K + + R + D +D++ L + Q E R
Sbjct: 1230 EKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQER 1283
Score = 29.6 bits (65), Expect = 4.0
Identities = 20/85 (23%), Positives = 44/85 (51%), Gaps = 14/85 (16%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKR----- 71
++Q + +QEE + RL KR+ + ++Q++ EQR R++ +E+R++
Sbjct: 586 RQQRLKREQEERLEQRL--------KREEVERLEQEERREQRLKREEPEEERRQQLLKSE 637
Query: 72 -KKLERQCQMEPNSDGHDRKRVRRD 95
++ RQ Q+ +R++R+
Sbjct: 638 EQEERRQQQLRREQQERREQRLKRE 662
Score = 29.6 bits (65), Expect = 4.0
Identities = 17/68 (25%), Positives = 38/68 (55%), Gaps = 6/68 (8%)
Query: 23 EDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEP 82
E+ EE ++ +L + E +RQ Q+ EQ+E R+Q+ K + + ++LE++ + E
Sbjct: 623 EEPEEERRQQLLKSEEQEERRQ------QQLRREQQERREQRLKREEEEERLEQRLKREH 676
Query: 83 NSDGHDRK 90
+ +++
Sbjct: 677 EEERREQE 684
Score = 28.9 bits (63), Expect = 6.9
Identities = 16/71 (22%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
Query: 11 ETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRK 70
E D++Q Q+ + E E +++ K+ + ++ +E+++L +++R+EKR+
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKR--RDRKSQEEKQLLREEREEKRR 1330
Query: 71 RKKLERQCQME 81
R++ +R+ + E
Sbjct: 1331 RQETDRKFREE 1341
Score = 28.5 bits (62), Expect = 9.0
Identities = 19/85 (22%), Positives = 46/85 (54%), Gaps = 6/85 (7%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQW----EEQRE--LRKQKRKEKRK 70
++Q + QEE ++ + E E +R+ ++ +++Q EE+RE LR+++ +E+R+
Sbjct: 302 REQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERRE 361
Query: 71 RKKLERQCQMEPNSDGHDRKRVRRD 95
++ Q + +++RR+
Sbjct: 362 QQLRREQEEERREQQLRREQQLRRE 386
Score = 28.5 bits (62), Expect = 9.0
Identities = 16/79 (20%), Positives = 46/79 (58%), Gaps = 3/79 (3%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLER 76
++Q + +QEE ++ + E +R+ ++L +++Q +++LR+++ + R+ ++L R
Sbjct: 347 REQQLRREQEEERREQQLRR-EQEEERREQQLRREQQLRREQQLRREQ--QLRREQQLRR 403
Query: 77 QCQMEPNSDGHDRKRVRRD 95
+ Q+ +++RR+
Sbjct: 404 EQQLRREQQLRREQQLRRE 422
Score = 28.5 bits (62), Expect = 9.0
Identities = 18/75 (24%), Positives = 39/75 (52%), Gaps = 2/75 (2%)
Query: 23 EDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEK--RKRKKLERQCQM 80
E +EE ++ +L E + Q + +Q + E+Q +Q R+E+ R+ ++L R+ Q+
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 413
Query: 81 EPNSDGHDRKRVRRD 95
+++RR+
Sbjct: 414 RREQQLRREQQLRRE 428
Score = 28.5 bits (62), Expect = 9.0
Identities = 11/80 (13%), Positives = 49/80 (61%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLER 76
++Q + +Q+ ++ +L + ++Q+++ ++++ E++ E +++++ KR++++
Sbjct: 397 REQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRD 456
Query: 77 QCQMEPNSDGHDRKRVRRDV 96
+ E ++ H+++R ++ +
Sbjct: 457 WLKREEETERHEQERRKQQL 476
Score = 28.5 bits (62), Expect = 9.0
Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 25 QEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNS 84
+EE +K R E K+ + +++ E+RE R+ + +E++ R++ E Q Q E
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ-QEEEQL 1063
Query: 85 DGHDRKRVRRDVVHSTLR 102
G +R+ RR + R
Sbjct: 1064 LGEERETRRRQELERQYR 1081
Score = 28.5 bits (62), Expect = 9.0
Identities = 14/45 (31%), Positives = 26/45 (57%)
Query: 51 QKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRRD 95
+K EE++ LR+Q+R+ K +++ + +CQ DR R R+
Sbjct: 1374 RKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE 1418
>gi|118766347 zinc finger CCCH-type domain containing 6 [Homo
sapiens]
Length = 1189
Score = 38.9 bits (89), Expect = 0.007
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 9/93 (9%)
Query: 11 ETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKE--- 67
E + D++ G ED E G E I +++ K+ KQK + R+ RK+ +KE
Sbjct: 5 EHAGHDREDGELEDGEIDDA-----GFEEIQEKEAKENEKQKSEKAYRKSRKKHKKEREK 59
Query: 68 -KRKRKKLERQCQMEPNSDGHDRKRVRRDVVHS 99
K KR+K E+ P+SD + DV H+
Sbjct: 60 KKSKRRKREKHKHNSPSSDDSSDYSLDSDVEHT 92
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 38.9 bits (89), Expect = 0.007
Identities = 21/75 (28%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
Query: 16 DKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLE 75
++++ +D+E Q+ E +R+M+K KQ++ E++ E +K+K KE +K K+ E
Sbjct: 526 EREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEK-EKELERQKEKEKELQKMKEQE 584
Query: 76 RQCQMEPNSDGHDRK 90
++C++E + + K
Sbjct: 585 KECELEKEREKLEEK 599
Score = 37.0 bits (84), Expect = 0.025
Identities = 24/120 (20%), Positives = 58/120 (48%), Gaps = 14/120 (11%)
Query: 15 VDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKL 74
+D+K GI E Q ++ R E + + K+L K+++ E ++E K + +++ K K+L
Sbjct: 488 LDEKLGILEKQPSPEEIRERE--REKEREREKELEKEQEQEREKEREKDRERQQEKEKEL 545
Query: 75 ERQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQRCYAENRR 134
E++ + + + ++ +++ + K+++K+ +Q + C E R
Sbjct: 546 EKEQEKQREMEKERKQEKEKELERQKEK------------EKELQKMKEQEKECELEKER 593
Score = 35.4 bits (80), Expect = 0.073
Identities = 21/71 (29%), Positives = 42/71 (59%), Gaps = 2/71 (2%)
Query: 11 ETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRK 70
E +++ E ++E ++ R E + ++Q K+ +K+ E+QRE+ K++++E K
Sbjct: 506 EREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQE--K 563
Query: 71 RKKLERQCQME 81
K+LERQ + E
Sbjct: 564 EKELERQKEKE 574
Score = 33.9 bits (76), Expect = 0.21
Identities = 18/60 (30%), Positives = 33/60 (55%)
Query: 23 EDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEP 82
E Q E +K R E + + +++ K+ QK E+++E +K +EK + K R+ +EP
Sbjct: 550 EKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEP 609
Score = 30.0 bits (66), Expect = 3.1
Identities = 20/79 (25%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
Query: 15 VDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKR-KEKRKRKK 73
V++ + E++E + + C KR +KL ++ E+R+++R KE+ + K+
Sbjct: 459 VERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKE 518
Query: 74 LERQCQMEPNSDGH-DRKR 91
LE++ + E + DR+R
Sbjct: 519 LEKEQEQEREKEREKDRER 537
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 38.1 bits (87), Expect = 0.011
Identities = 54/247 (21%), Positives = 110/247 (44%), Gaps = 20/247 (8%)
Query: 27 ESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDG 86
E+ K +L + +P Q+K ++QK E +++ + K + +K++E+
Sbjct: 659 ENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVYL------- 711
Query: 87 HDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQRCYAENRRALHPVQFYLTSH 146
D K ++ + T+ + + L V +D+KK H I NR+ L Q Y T
Sbjct: 712 -DNKLLKEQAHNLTIEM--KNHYVPLKVSEDMKKSHDAI--IDDLNRKLLDVTQKY-TEK 765
Query: 147 GGQLKKNMDEND---KGWVNWKDIHIKPE-HYSELIK-KEDLIYLTSDSPNILKELDESK 201
+++K + END K + + + PE H E+I K +++ L + K+ E +
Sbjct: 766 KLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQ 825
Query: 202 AYVIGGLVDHNHHKGLTYKQASDYGIN-HAQLPLGNFVKMNSRKVLAVNHVFE-IILEYL 259
+ ++ + K + Q + ++ L + + +R++L V FE I E++
Sbjct: 826 EKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFV 885
Query: 260 ETRDWQE 266
+ +D E
Sbjct: 886 KIKDKNE 892
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 38.1 bits (87), Expect = 0.011
Identities = 54/247 (21%), Positives = 110/247 (44%), Gaps = 20/247 (8%)
Query: 27 ESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDG 86
E+ K +L + +P Q+K ++QK E +++ + K + +K++E+
Sbjct: 672 ENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVYL------- 724
Query: 87 HDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQRCYAENRRALHPVQFYLTSH 146
D K ++ + T+ + + L V +D+KK H I NR+ L Q Y T
Sbjct: 725 -DNKLLKEQAHNLTIEM--KNHYVPLKVSEDMKKSHDAI--IDDLNRKLLDVTQKY-TEK 778
Query: 147 GGQLKKNMDEND---KGWVNWKDIHIKPE-HYSELIK-KEDLIYLTSDSPNILKELDESK 201
+++K + END K + + + PE H E+I K +++ L + K+ E +
Sbjct: 779 KLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQ 838
Query: 202 AYVIGGLVDHNHHKGLTYKQASDYGIN-HAQLPLGNFVKMNSRKVLAVNHVFE-IILEYL 259
+ ++ + K + Q + ++ L + + +R++L V FE I E++
Sbjct: 839 EKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFV 898
Query: 260 ETRDWQE 266
+ +D E
Sbjct: 899 KIKDKNE 905
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 37.4 bits (85), Expect = 0.019
Identities = 25/123 (20%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 9 FIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEK 68
F++ S K + DQE RLG+ + ++R+ K+ +K++ + E +K+K +EK
Sbjct: 325 FVKGSTEKNKLRLQRDQE-----RLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEK 379
Query: 69 RKRKKLERQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQRC 128
++K R+ + + + +++R++ + + ++ + ++ K+L ++ +R
Sbjct: 380 ELKEKERREKREKDEKEKAEKQRLKEE-RRKERQEALEAKLEEKRKKEEEKRLREEEKRI 438
Query: 129 YAE 131
AE
Sbjct: 439 KAE 441
Score = 29.6 bits (65), Expect = 4.0
Identities = 17/73 (23%), Positives = 42/73 (57%)
Query: 4 EMLPAFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQ 63
E L + + + K+ E++E +K R + + ++ K+ +K+++ +E++E +
Sbjct: 358 EKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEA 417
Query: 64 KRKEKRKRKKLER 76
K +EKRK+++ +R
Sbjct: 418 KLEEKRKKEEEKR 430
>gi|157785548 PAS domain containing 1 [Homo sapiens]
Length = 773
Score = 37.4 bits (85), Expect = 0.019
Identities = 22/70 (31%), Positives = 43/70 (61%), Gaps = 7/70 (10%)
Query: 8 AFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKE 67
AF + V ++Q + E Q + L E + + R+ +K+ KQK+ +E+++L++QK +E
Sbjct: 476 AFNQQQLVQQEQHLKEQQRQ-----LREQLQQL--REQRKVQKQKKMQEKKKLQEQKMQE 528
Query: 68 KRKRKKLERQ 77
K+K ++ RQ
Sbjct: 529 KKKLQEQRRQ 538
>gi|18093112 ABT1-associated protein [Homo sapiens]
Length = 851
Score = 37.4 bits (85), Expect = 0.019
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Query: 17 KKQGINEDQEESQK--PRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKL 74
+K+G D E K P L E E + K +++ K WE+ E +K+K++ KRK+K L
Sbjct: 593 EKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKAL 652
Query: 75 ERQCQME 81
+ E
Sbjct: 653 AEEASEE 659
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 37.0 bits (84), Expect = 0.025
Identities = 26/67 (38%), Positives = 40/67 (59%), Gaps = 13/67 (19%)
Query: 23 EDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRK--------RKKL 74
E E+ +K R E E KRQ++ +KQ E+QREL +Q+ +E+RK +++L
Sbjct: 387 ERAEQERKER--ERQEQERKRQLEL---EKQLEKQRELERQREEERRKEIERREAAKREL 441
Query: 75 ERQCQME 81
ERQ Q+E
Sbjct: 442 ERQRQLE 448
Score = 29.6 bits (65), Expect = 4.0
Identities = 19/85 (22%), Positives = 42/85 (49%), Gaps = 12/85 (14%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKK--- 73
K++ E +K R + + ++Q K+ + Q E + RK++ +++++RK+
Sbjct: 354 KRENFERGNLELEKRR-----QALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLE 408
Query: 74 ----LERQCQMEPNSDGHDRKRVRR 94
LE+Q ++E + RK + R
Sbjct: 409 LEKQLEKQRELERQREEERRKEIER 433
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 37.0 bits (84), Expect = 0.025
Identities = 26/67 (38%), Positives = 40/67 (59%), Gaps = 13/67 (19%)
Query: 23 EDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRK--------RKKL 74
E E+ +K R E E KRQ++ +KQ E+QREL +Q+ +E+RK +++L
Sbjct: 387 ERAEQERKER--ERQEQERKRQLEL---EKQLEKQRELERQREEERRKEIERREAAKREL 441
Query: 75 ERQCQME 81
ERQ Q+E
Sbjct: 442 ERQRQLE 448
Score = 29.6 bits (65), Expect = 4.0
Identities = 19/85 (22%), Positives = 42/85 (49%), Gaps = 12/85 (14%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKK--- 73
K++ E +K R + + ++Q K+ + Q E + RK++ +++++RK+
Sbjct: 354 KRENFERGNLELEKRR-----QALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLE 408
Query: 74 ----LERQCQMEPNSDGHDRKRVRR 94
LE+Q ++E + RK + R
Sbjct: 409 LEKQLEKQRELERQREEERRKEIER 433
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 37.0 bits (84), Expect = 0.025
Identities = 21/74 (28%), Positives = 39/74 (52%)
Query: 27 ESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDG 86
E K +L + E + + K KQ++ E ++E +++ + +RKR++ E + + E D
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDR 287
Query: 87 HDRKRVRRDVVHST 100
RKR R HS+
Sbjct: 288 ERRKRSRSRSRHSS 301
Score = 32.0 bits (71), Expect = 0.81
Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 4/72 (5%)
Query: 23 EDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKL-ERQCQME 81
+++EE +K R E E KR+ ++ ++K+ RE RK+ R R + +R+C
Sbjct: 252 QEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCS-- 309
Query: 82 PNSDGHDRKRVR 93
S H R R R
Sbjct: 310 -RSRDHKRSRSR 320
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 37.0 bits (84), Expect = 0.025
Identities = 21/74 (28%), Positives = 39/74 (52%)
Query: 27 ESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDG 86
E K +L + E + + K KQ++ E ++E +++ + +RKR++ E + + E D
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDR 287
Query: 87 HDRKRVRRDVVHST 100
RKR R HS+
Sbjct: 288 ERRKRSRSRSRHSS 301
Score = 32.0 bits (71), Expect = 0.81
Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 4/72 (5%)
Query: 23 EDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKL-ERQCQME 81
+++EE +K R E E KR+ ++ ++K+ RE RK+ R R + +R+C
Sbjct: 252 QEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCS-- 309
Query: 82 PNSDGHDRKRVR 93
S H R R R
Sbjct: 310 -RSRDHKRSRSR 320
>gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo
sapiens]
Length = 600
Score = 36.6 bits (83), Expect = 0.033
Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 4 EMLPAFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQ 63
+ +P + T + K I E Q QK + E +K IK K W +Q+ +++
Sbjct: 473 DFVPVDVNTDTIPFKDKIREKQR--QKLLEQQRREKTENEGRRKFIKNKAWSKQKAKKEK 530
Query: 64 KRKEKRKRKKLE 75
K+K KRK+ E
Sbjct: 531 KKKMNEKRKREE 542
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 36.2 bits (82), Expect = 0.043
Identities = 21/73 (28%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
Query: 23 EDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKR-KKLERQCQME 81
E++E ++ R E E K + KK K+++ +E ++++RKE+RKR ++ ER+ + E
Sbjct: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
Query: 82 PNSDGHDRKRVRR 94
+RK ++
Sbjct: 153 EREKERERKERKK 165
Score = 35.8 bits (81), Expect = 0.056
Identities = 20/82 (24%), Positives = 47/82 (57%), Gaps = 3/82 (3%)
Query: 13 SNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQR---ELRKQKRKEKR 69
S + +++ E ++E +K R E + +R+ +K ++K+ + +R E + +++KE+R
Sbjct: 36 SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER 95
Query: 70 KRKKLERQCQMEPNSDGHDRKR 91
+RKK R+ + + + RK+
Sbjct: 96 ERKKRRREKENKEGEEKEKRKK 117
Score = 35.8 bits (81), Expect = 0.056
Identities = 20/84 (23%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
Query: 11 ETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRK 70
E ++KQ +++E +K R ++++ KK ++K+ E+++ RK+K + K++
Sbjct: 162 ERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKE 221
Query: 71 RKKLERQCQMEPNSDGHDRKRVRR 94
R+K +RQ G ++ R+
Sbjct: 222 RQK-DRQTNWREKERGKRERKERK 244
Score = 35.0 bits (79), Expect = 0.096
Identities = 22/80 (27%), Positives = 46/80 (57%), Gaps = 9/80 (11%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLER 76
+++ N++ EE +K + E K++ + K+ + E++E RK++ +++R+RKK ER
Sbjct: 101 RREKENKEGEEKEKRKKKE------KKERGRTSKEGKERERKEERKREERKERERKKEER 154
Query: 77 QCQMEPNSDGHDRKRVRRDV 96
+ + E +KR R+ V
Sbjct: 155 EKERERK---ERKKRERKQV 171
Score = 34.3 bits (77), Expect = 0.16
Identities = 26/89 (29%), Positives = 49/89 (55%), Gaps = 7/89 (7%)
Query: 12 TSNVDKKQGINED---QEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRK-- 66
TS K++ E+ +E ++ R E E +R+ +K ++KQ E+ E RK+K +
Sbjct: 126 TSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKE 185
Query: 67 -EKRKRKKLERQCQMEPNSDGHDRKRVRR 94
+KR+R + ER+ + E + +RK+ R+
Sbjct: 186 RKKRERNRKERKKERE-RKERRERKKERK 213
Score = 33.9 bits (76), Expect = 0.21
Identities = 19/80 (23%), Positives = 47/80 (58%), Gaps = 12/80 (15%)
Query: 17 KKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLER 76
+K+G E + E +K R R+ +K ++++ E +RE K+++K +RK+++ ER
Sbjct: 48 RKEGKKERESERKKER----------REREKRKREREKERKRERGKKEKKGERKKEERER 97
Query: 77 QCQM--EPNSDGHDRKRVRR 94
+ + + N +G ++++ ++
Sbjct: 98 KKRRREKENKEGEEKEKRKK 117
Score = 33.5 bits (75), Expect = 0.28
Identities = 14/46 (30%), Positives = 33/46 (71%)
Query: 50 KQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRRD 95
++K+ +RE RK++R+++RKR++ +++ + E + +RK+ RR+
Sbjct: 58 ERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRRE 103
Score = 33.1 bits (74), Expect = 0.36
Identities = 20/70 (28%), Positives = 40/70 (57%), Gaps = 4/70 (5%)
Query: 25 QEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNS 84
+E +K + GE + +R+ KK ++K+ +E E K+K+KEK++R + ++ +
Sbjct: 79 RERGKKEKKGERKK--EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERK 136
Query: 85 DGHDRKRVRR 94
+ +RKR R
Sbjct: 137 E--ERKREER 144
Score = 32.7 bits (73), Expect = 0.48
Identities = 26/96 (27%), Positives = 49/96 (51%), Gaps = 11/96 (11%)
Query: 10 IETSNVDKKQGINEDQEE--SQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKR-- 65
IET KK+ +E ++E ++ R E + + + KK K ++ +E+RE +K++R
Sbjct: 45 IETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREK 104
Query: 66 -------KEKRKRKKLERQCQMEPNSDGHDRKRVRR 94
KEKRK+K+ + + + +RK R+
Sbjct: 105 ENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERK 140
Score = 31.2 bits (69), Expect = 1.4
Identities = 20/80 (25%), Positives = 45/80 (56%), Gaps = 6/80 (7%)
Query: 16 DKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLE 75
+KK+ +E ++ R E KR+ +K ++K+ E ++E R++K ++KR+RK++
Sbjct: 119 EKKERGRTSKEGKERERKEE-----RKREERKERERKKEEREKE-RERKERKKRERKQVG 172
Query: 76 RQCQMEPNSDGHDRKRVRRD 95
+ + + +RK+ R+
Sbjct: 173 EKEEERKEKERKERKKRERN 192
Score = 30.8 bits (68), Expect = 1.8
Identities = 17/84 (20%), Positives = 47/84 (55%), Gaps = 3/84 (3%)
Query: 11 ETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRK 70
E ++K+ E + E ++ + E + K + +K ++K+ +++ RK+++KE+ +
Sbjct: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
Query: 71 RKKLERQCQMEPNSDGHDRKRVRR 94
+++ ER+ + + +RK+ R+
Sbjct: 203 KERRERKKERKKK---EERKKERQ 223
Score = 30.0 bits (66), Expect = 3.1
Identities = 18/84 (21%), Positives = 45/84 (53%), Gaps = 5/84 (5%)
Query: 16 DKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQREL-----RKQKRKEKRK 70
+K+ E++E+ +K E + + ++ ++++ EE++E ++K +E+++
Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKE 162
Query: 71 RKKLERQCQMEPNSDGHDRKRVRR 94
RKK ER+ E + +++R R
Sbjct: 163 RKKRERKQVGEKEEERKEKERKER 186
Score = 29.6 bits (65), Expect = 4.0
Identities = 13/65 (20%), Positives = 37/65 (56%)
Query: 30 KPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDGHDR 89
KP G + + + +++ +K+ +++RE ++K + +R+++K ER+ + + ++
Sbjct: 27 KPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEK 86
Query: 90 KRVRR 94
K R+
Sbjct: 87 KGERK 91
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 36.2 bits (82), Expect = 0.043
Identities = 31/128 (24%), Positives = 64/128 (50%), Gaps = 13/128 (10%)
Query: 2 SSEMLPAFIETSNVDKKQGINED--QEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRE 59
++++ P + V K+ + + +EE +KP+ E + K +KK K K+ E ++E
Sbjct: 625 ATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKK-EVAKKEDKTPIKKEEKPKKEEVKKE 683
Query: 60 LRKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIK 119
++K+ +KE++K K E + + P K V+++V + + + K+IK
Sbjct: 684 VKKEIKKEEKKEPKKEVKKETPP-------KEVKKEVKKEEKK---EVKKEEKEPKKEIK 733
Query: 120 KLHKQIQR 127
KL K ++
Sbjct: 734 KLPKDAKK 741
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 36.2 bits (82), Expect = 0.043
Identities = 23/117 (19%), Positives = 63/117 (53%), Gaps = 13/117 (11%)
Query: 24 DQEESQKPRLGEGC--EPISKRQMKKLIKQKQWEEQRELR--KQKRKEKRKRKKLERQCQ 79
+Q++ Q+ RL E E ++RQ ++ ++++ EE+R L +++RKE+ +R++ E + +
Sbjct: 400 EQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKR 459
Query: 80 MEPNSDGHDRKRVRRDVVHSTL---------RLIIDCSFDHLMVLKDIKKLHKQIQR 127
+ R+++ + H + ++++C + + + ++L +Q+Q+
Sbjct: 460 RVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQ 516
Score = 35.0 bits (79), Expect = 0.096
Identities = 27/101 (26%), Positives = 56/101 (55%), Gaps = 8/101 (7%)
Query: 24 DQEESQKPRLGEGCEPIS--KRQMKKLIKQKQWE------EQRELRKQKRKEKRKRKKLE 75
+QEE ++ L E + I K Q ++L +Q++ E ++RE R+++++EKR+ ++LE
Sbjct: 383 EQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELE 442
Query: 76 RQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLK 116
R+ + E + ++ R + +R ++ HL VL+
Sbjct: 443 RRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQ 483
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,467,674
Number of Sequences: 37866
Number of extensions: 646836
Number of successful extensions: 8742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 204
Number of HSP's successfully gapped in prelim test: 218
Number of HSP's that attempted gapping in prelim test: 5250
Number of HSP's gapped (non-prelim): 2406
length of query: 339
length of database: 18,247,518
effective HSP length: 103
effective length of query: 236
effective length of database: 14,347,320
effective search space: 3385967520
effective search space used: 3385967520
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.