Guide to the Human Genome
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Search of human proteins with 22748641

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22748641 CHMP family, member 7 [Homo sapiens]
         (453 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22748641 CHMP family, member 7 [Homo sapiens]                      888   0.0  
gi|22748643 chromatin modifying protein 4C [Homo sapiens]              65   2e-10
gi|28827795 chromatin modifying protein 4B [Homo sapiens]              64   4e-10
gi|40548422 chromatin modifying protein 4A [Homo sapiens]              60   4e-09
gi|189409150 chromatin modifying protein 5 [Homo sapiens]              51   2e-06
gi|31542306 chromatin modifying protein 1B [Homo sapiens]              38   0.022
gi|157388975 coiled-coil domain containing 99 [Homo sapiens]           37   0.028
gi|38044112 restin isoform b [Homo sapiens]                            37   0.048
gi|4506751 restin isoform a [Homo sapiens]                             37   0.048
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ...    37   0.048
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   37   0.048
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]                    35   0.14 
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]                    35   0.14 
gi|109134347 NY-REN-58 antigen [Homo sapiens]                          35   0.14 
gi|109134355 NY-REN-58 antigen [Homo sapiens]                          35   0.14 
gi|21389505 janus kinase and microtubule interacting protein 1 i...    35   0.18 
gi|150456473 janus kinase and microtubule interacting protein 1 ...    35   0.18 
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    35   0.18 
gi|14165274 golgi-associated microtubule-binding protein HOOK3 [...    35   0.18 
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    35   0.18 
gi|110815815 centlein isoform 1 [Homo sapiens]                         34   0.24 
gi|237858621 polyamine modulated factor 1 binding protein 1 isof...    34   0.31 
gi|237858619 polyamine modulated factor 1 binding protein 1 isof...    34   0.31 
gi|223005859 WD repeat domain 67 isoform 1 [Homo sapiens]              33   0.41 
gi|39725952 angiogenic factor VG5Q [Homo sapiens]                      33   0.41 
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    33   0.53 
gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]                 33   0.53 
gi|45439327 periplakin [Homo sapiens]                                  33   0.53 
gi|38570058 hypothetical protein LOC80129 [Homo sapiens]               33   0.69 
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform...    33   0.69 

>gi|22748641 CHMP family, member 7 [Homo sapiens]
          Length = 453

 Score =  888 bits (2294), Expect = 0.0
 Identities = 453/453 (100%), Positives = 453/453 (100%)

Query: 1   MWSPEREAEAPAGGDPAGLLPPEWEEDEERMSFLFSAFKRSREVNSTDWDSKMGFWAPLV 60
           MWSPEREAEAPAGGDPAGLLPPEWEEDEERMSFLFSAFKRSREVNSTDWDSKMGFWAPLV
Sbjct: 1   MWSPEREAEAPAGGDPAGLLPPEWEEDEERMSFLFSAFKRSREVNSTDWDSKMGFWAPLV 60

Query: 61  LSHSRRQGVVRLRLRDLQEAFQRKGSVPLGLATVLQDLLRRGELQRESDFMASVDSSWIS 120
           LSHSRRQGVVRLRLRDLQEAFQRKGSVPLGLATVLQDLLRRGELQRESDFMASVDSSWIS
Sbjct: 61  LSHSRRQGVVRLRLRDLQEAFQRKGSVPLGLATVLQDLLRRGELQRESDFMASVDSSWIS 120

Query: 121 WGVGVFLLKPLKWTLSNMLGDNKVPAEEVLVAVELLKEKAEEVYRLYQNSPLSSHPVVAL 180
           WGVGVFLLKPLKWTLSNMLGDNKVPAEEVLVAVELLKEKAEEVYRLYQNSPLSSHPVVAL
Sbjct: 121 WGVGVFLLKPLKWTLSNMLGDNKVPAEEVLVAVELLKEKAEEVYRLYQNSPLSSHPVVAL 180

Query: 181 SELSTLCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVG 240
           SELSTLCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVG
Sbjct: 181 SELSTLCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVG 240

Query: 241 VYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHA 300
           VYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHA
Sbjct: 241 VYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHA 300

Query: 301 KLDTVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDE 360
           KLDTVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDE
Sbjct: 301 KLDTVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDE 360

Query: 361 VSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRISDAE 420
           VSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRISDAE
Sbjct: 361 VSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRISDAE 420

Query: 421 LEAELEKLSLSEGGLVPSSKSPKRQLEPTLKPL 453
           LEAELEKLSLSEGGLVPSSKSPKRQLEPTLKPL
Sbjct: 421 LEAELEKLSLSEGGLVPSSKSPKRQLEPTLKPL 453


>gi|22748643 chromatin modifying protein 4C [Homo sapiens]
          Length = 233

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 55/194 (28%), Positives = 95/194 (48%), Gaps = 17/194 (8%)

Query: 219 KIVKFARG-----PRAKVSPVNDVDVGVYQLMQSEQLLSRKVESLSQEAERCKEEARRAC 273
           K+ KF +G      RA  SP       + +L ++E++L +K E L    +R   E   A 
Sbjct: 3   KLGKFFKGGGSSKSRAAPSPQE----ALVRLRETEEMLGKKQEYLENRIQR---EIALAK 55

Query: 274 RAG--KKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQTDQMVFNAYQAGVGA 331
           + G   K+ AL++LK K+R EK++  +   L T++   + +  S T+  V         A
Sbjct: 56  KHGTQNKRAALQALKRKKRFEKQLTQIDGTLSTIEFQREALENSHTNTEVLRNMGFAAKA 115

Query: 332 LKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDT 391
           +K   +++ + K + L+ +I E  D   E+S+  +  V  G DFD +EL  EL+ L Q+ 
Sbjct: 116 MKSVHENMDLNKIDDLMQEITEQQDIAQEISEAFSQRVGFGDDFDEDELMAELEELEQEE 175

Query: 392 TKEPLD---LPDNP 402
             + +    LP+ P
Sbjct: 176 LNKKMTNIRLPNVP 189


>gi|28827795 chromatin modifying protein 4B [Homo sapiens]
          Length = 224

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 48/189 (25%), Positives = 94/189 (49%), Gaps = 11/189 (5%)

Query: 241 VYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAG--KKQLALRSLKAKQRTEKRIEAL 298
           + +L  +E++LS+K E L ++ E   +E   A + G   K+ AL++LK K+R EK++  +
Sbjct: 26  IQRLRDTEEMLSKKQEFLEKKIE---QELTAAKKHGTKNKRAALQALKRKKRYEKQLAQI 82

Query: 299 HAKLDTVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQ 358
              L T++   + +  + T+  V         A+K +  ++ ++K + L+  I +  +  
Sbjct: 83  DGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIADQQELA 142

Query: 359 DEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRISD 418
           +E+S  ++  V  G +FD +EL  EL+ L Q+      +L  N        +VP P +  
Sbjct: 143 EEISTAISKPVGFGEEFDEDELMAELEELEQE------ELDKNLLEISGPETVPLPNVPS 196

Query: 419 AELEAELEK 427
             L ++  K
Sbjct: 197 IALPSKPAK 205


>gi|40548422 chromatin modifying protein 4A [Homo sapiens]
          Length = 265

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 37/156 (23%), Positives = 84/156 (53%), Gaps = 1/156 (0%)

Query: 241 VYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHA 300
           + +L ++E++L +K E L Q+ ++  + A++     K+  AL++L+ K+R E+++     
Sbjct: 66  IQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRA-ALQALRRKKRFEQQLAQTDG 124

Query: 301 KLDTVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDE 360
            L T++   + I  + T+  V    +    ++K + +D+ ++K + L+  I E  +   +
Sbjct: 125 TLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQ 184

Query: 361 VSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPL 396
           +S  ++  +  G D D +EL +EL+ L Q+   + L
Sbjct: 185 ISDAISRPMGFGDDVDEDELLEELEELEQEELAQEL 220


>gi|189409150 chromatin modifying protein 5 [Homo sapiens]
          Length = 219

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 36/142 (25%), Positives = 73/142 (51%), Gaps = 7/142 (4%)

Query: 251 LSRKVESLSQEAERCKEEARRACRAGK-----KQLALRSLKAKQRTEKRIEALHAKLDTV 305
           + +K+  L  E  + K++ ++  R G      KQ ALR LK K+  E++ + L  +   +
Sbjct: 31  IDKKISRLDAELVKYKDQIKKM-REGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNM 89

Query: 306 QGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTL 365
           +     I + +  +   +A + GV  +K + K V +++ E L DQ++++ +  +E+ + L
Sbjct: 90  EQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEAL 149

Query: 366 AGGVTNGLDFDSEELEKELDIL 387
           +       + D ++LE ELD L
Sbjct: 150 SRSYGTP-ELDEDDLEAELDAL 170


>gi|31542306 chromatin modifying protein 1B [Homo sapiens]
          Length = 199

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 34/171 (19%), Positives = 86/171 (50%), Gaps = 13/171 (7%)

Query: 234 VNDVDVGVYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEK 293
           +++++  ++ L  + + LSR  +   +E +  K + ++A + G  ++A   + A+    +
Sbjct: 1   MSNMEKHLFNLKFAAKELSRSAKKCDKEEKAEKAKIKKAIQKGNMEVA--RIHAENAIRQ 58

Query: 294 RIEALH-----AKLDTVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLV 348
           + +A++     A++D V     R+  + T   V  +    V ++  ++K + +EK  +L+
Sbjct: 59  KNQAVNFLRMSARVDAVAA---RVQTAVTMGKVTKSMAGVVKSMDATLKTMNLEKISALM 115

Query: 349 DQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEP-LDL 398
           D+ +   +T D  +Q +   +++     +   + ++D+LLQ+   E  LDL
Sbjct: 116 DKFEHQFETLDVQTQQMEDTMSSTTTLTTP--QNQVDMLLQEMADEAGLDL 164


>gi|157388975 coiled-coil domain containing 99 [Homo sapiens]
          Length = 605

 Score = 37.4 bits (85), Expect = 0.028
 Identities = 45/202 (22%), Positives = 92/202 (45%), Gaps = 11/202 (5%)

Query: 242 YQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAK 301
           Y L +  +L SR +ESLS E E  K++ +      ++QL+    +     + +IE L  +
Sbjct: 60  YTLQREVELKSRMLESLSCECEAIKQQQKMHLEKLEEQLSRSHGQEVNELKTKIEKLKVE 119

Query: 302 LDTVQGILDRIYASQTDQMVFNAYQ-AGVGALKLSMKDVTVEKAESLVDQIQELCDTQDE 360
           LD       R+   Q    V +  +     + +L +    V+++ S      ++  T+ E
Sbjct: 120 LDEA-----RLSEKQLKHQVDHQKELLSCKSEELRVMSERVQESMSSEMLALQIELTEME 174

Query: 361 VSQTLAGGVTNGLDFDSEELEKELDILLQ--DTTKEPLDLPDNPRNRHFTNSVPNPRISD 418
             +T      N L +  E+LE  +  L++  D  KE  +  +     ++ N++   R+++
Sbjct: 175 SMKTTLKEEVNELQYRQEQLELLITNLMRQVDRLKEEKEEREKEAVSYY-NALEKARVAN 233

Query: 419 AELEAELEKLSLSEGGLVPSSK 440
            +L+ +L++    +  L P+SK
Sbjct: 234 QDLQVQLDQ--ALQQALDPNSK 253


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 44/243 (18%), Positives = 101/243 (41%), Gaps = 36/243 (14%)

Query: 193  DERTFYLVLLQLQKEKRVTVLEQ----NGEKIVKFARGPRAKVSPVNDVDVGVYQLMQSE 248
            DER   L+  + + E  +  + +    N  ++ K     R K   V ++ + + +  ++ 
Sbjct: 867  DEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENA 926

Query: 249  QLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGI 308
              L + +E ++ +AE+ ++EA +     KK+L           E+++  L  K++T    
Sbjct: 927  SFLQKSIEDMTVKAEQSQQEAAKKHEEEKKEL-----------ERKLSDLEKKMETSHNQ 975

Query: 309  LDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGG 368
               + A          Y+      K   +++     ++L+D   +L   ++E        
Sbjct: 976  CQELKA---------RYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREE-------- 1018

Query: 369  VTNGLDFDSEELEKELD-ILLQDTTKEPLDLPD--NPRNRHFTNSVPNPRISDAELEAEL 425
              +GL  + EEL K+ D      T ++ + + +           S+ + + ++A+L+ EL
Sbjct: 1019 -NSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNEL 1077

Query: 426  EKL 428
            + L
Sbjct: 1078 DTL 1080


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 44/243 (18%), Positives = 101/243 (41%), Gaps = 36/243 (14%)

Query: 193  DERTFYLVLLQLQKEKRVTVLEQ----NGEKIVKFARGPRAKVSPVNDVDVGVYQLMQSE 248
            DER   L+  + + E  +  + +    N  ++ K     R K   V ++ + + +  ++ 
Sbjct: 902  DEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENA 961

Query: 249  QLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGI 308
              L + +E ++ +AE+ ++EA +     KK+L           E+++  L  K++T    
Sbjct: 962  SFLQKSIEDMTVKAEQSQQEAAKKHEEEKKEL-----------ERKLSDLEKKMETSHNQ 1010

Query: 309  LDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGG 368
               + A          Y+      K   +++     ++L+D   +L   ++E        
Sbjct: 1011 CQELKA---------RYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREE-------- 1053

Query: 369  VTNGLDFDSEELEKELD-ILLQDTTKEPLDLPD--NPRNRHFTNSVPNPRISDAELEAEL 425
              +GL  + EEL K+ D      T ++ + + +           S+ + + ++A+L+ EL
Sbjct: 1054 -NSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNEL 1112

Query: 426  EKL 428
            + L
Sbjct: 1113 DTL 1115


>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
            sapiens]
          Length = 2346

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 24/61 (39%), Positives = 32/61 (52%), Gaps = 5/61 (8%)

Query: 243  QLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKL 302
            QL Q  QL  R    LS +  + +++     +AG + LALR  +  Q  EK IE L AKL
Sbjct: 1533 QLAQGSQLTERLTSKLSTKDHKSEKD-----QAGLEPLALRLSRELQEKEKVIEVLQAKL 1587

Query: 303  D 303
            D
Sbjct: 1588 D 1588


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 58/277 (20%), Positives = 116/277 (41%), Gaps = 40/277 (14%)

Query: 156  LKEKAEEVYRLYQNSPLSSHPVVALSELSTLCANSCPDE---------RTFYLVLLQLQK 206
            LK+K+EEVY L +   + +H +   SE + +  ++   +         R   L   Q + 
Sbjct: 876  LKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKL 935

Query: 207  EKRVTVLEQ--------NGEKIVKFARGPRAKVSPVNDVDVGVYQLMQSEQLLSRKVESL 258
            EK+V+ LEQ        + EK+ K      +     +     V +L  + + +  +++  
Sbjct: 936  EKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQY 995

Query: 259  SQEAERCKEEARRACRAGK------KQLALRSLKAKQRTEKRIEALHAKLDTVQGILDR- 311
             +E  + ++E     R G+       QL +   + K   EK+  A+  +L+ +Q   +  
Sbjct: 996  KEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAV-KELEKLQHSTETE 1054

Query: 312  -IYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVT 370
               A Q  +++    Q   G LK +++            Q+QEL D   +   +L    T
Sbjct: 1055 LTEALQKREVLETELQNAHGELKSTLR------------QLQELRDVLQKAQLSLEEKYT 1102

Query: 371  NGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHF 407
               D  +E  E +++I  +D  +E L++    + R++
Sbjct: 1103 TIKDLTAELRECKMEI--EDKKQELLEMDQALKERNW 1137


>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
          Length = 247

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 43/186 (23%), Positives = 84/186 (45%), Gaps = 13/186 (6%)

Query: 249 QLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGI 308
           + + RK++ L Q+A+  +E A R  R  + +      +A+++ E  + +L+ ++  V+  
Sbjct: 8   EAVKRKIQVLQQQADDAEERAERLQREVEGE-----RRAREQAEAEVASLNRRIQLVEEE 62

Query: 309 LDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGG 368
           LDR  A +         +    A   S + + V +  +L D  +E  + Q E+    A  
Sbjct: 63  LDR--AQERLATALQKLEEAEKAADESERGMKVIENRALKD--EEKMELQ-EIQLKEAKH 117

Query: 369 VTNGLDFDSEELEKELDILLQD--TTKEPLDLPDNPRNRHFTNSVPNPRISDAELEAELE 426
           +    D   EE+ ++L I+  D   T+E  +L ++ +       + N   +   LEA+ E
Sbjct: 118 IAEEADRKYEEVARKLVIIEGDLERTEERAELAES-KCSELEEELKNVTNNLKSLEAQAE 176

Query: 427 KLSLSE 432
           K S  E
Sbjct: 177 KYSQKE 182


>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
          Length = 248

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 43/186 (23%), Positives = 84/186 (45%), Gaps = 13/186 (6%)

Query: 249 QLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGI 308
           + + RK++ L Q+A+  +E A R  R  + +      +A+++ E  + +L+ ++  V+  
Sbjct: 8   EAVKRKIQVLQQQADDAEERAERLQREVEGE-----RRAREQAEAEVASLNRRIQLVEEE 62

Query: 309 LDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGG 368
           LDR  A +         +    A   S + + V +  +L D  +E  + Q E+    A  
Sbjct: 63  LDR--AQERLATALQKLEEAEKAADESERGMKVIENRALKD--EEKMELQ-EIQLKEAKH 117

Query: 369 VTNGLDFDSEELEKELDILLQD--TTKEPLDLPDNPRNRHFTNSVPNPRISDAELEAELE 426
           +    D   EE+ ++L I+  D   T+E  +L ++ +       + N   +   LEA+ E
Sbjct: 118 IAEEADRKYEEVARKLVIIEGDLERTEERAELAES-KCSELEEELKNVTNNLKSLEAQAE 176

Query: 427 KLSLSE 432
           K S  E
Sbjct: 177 KYSQKE 182


>gi|109134347 NY-REN-58 antigen [Homo sapiens]
          Length = 701

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 94/444 (21%), Positives = 176/444 (39%), Gaps = 57/444 (12%)

Query: 7   EAEAPAGGDPAGLLPPEWEEDEERMSFLFSAF-KRSREVNSTDWDSKMGFWAPLVLSHSR 65
           EAE  +    A  L  E +   E+ +FL +   K  RE+N+     K        L HS 
Sbjct: 267 EAEKQSANLRAERLEKELQSSSEQNTFLINKLHKAEREINTLSSKVKE-------LKHSN 319

Query: 66  RQGVVRLRL---RDLQEAFQRKGSVPLGLATVLQDL-LRRGELQRESDFMASVDSSWISW 121
           +  +  ++L   R   E  + +  +   L  +  D  + +  ++     +   D   I  
Sbjct: 320 KLEITDIKLETARAKSELERERNKIQSELDGLQSDNEILKAAVEHHKVLLVEKDRELIR- 378

Query: 122 GVGVFLLKPLKWTLSNMLGDNKVPAEEVLVAVELLKEKAEEVYRLYQNSPLSSHPVVALS 181
              V   K   +    +L D K+  E  L  +E +K +  +V+R  +             
Sbjct: 379 --KVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVE-HDVWRQSEKDQYEEK------ 429

Query: 182 ELSTLCANSCPDERTFY-LVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVG 240
               L A+   +E T   L  ++L+ ++++  +E N EK        + ++S    + + 
Sbjct: 430 ----LRASQMAEEITRKELQSVRLKLQQQIVTIE-NAEKEKNENSDLKQQIS---SLQIQ 481

Query: 241 VYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKA-KQRTEKRIEALH 299
           V  L QSE  L    + L +  ER K+E    CR  + Q     L+A K   EK+I+ L 
Sbjct: 482 VTSLAQSENDLLNSNQMLKEMVERLKQE----CRNFRSQAEKAQLEAEKTLEEKQIQWLE 537

Query: 300 AKLDTVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQD 359
            K    + I DR    + +Q      +A +   K   K +   K + L ++++ L   ++
Sbjct: 538 EKHKLHERITDR--EEKYNQAKEKLQRAAIAQKK--RKSLHENKLKRLQEKVEVLEAKKE 593

Query: 360 EVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPD-NPRNRHFTNSVPNPRISD 418
           E            L+ +++ L ++ ++  +D T+    L D   R+  F + +  P +  
Sbjct: 594 E------------LETENQVLNRQ-NVPFEDYTRLQKRLKDIQRRHNEFRSLILVPNMPP 640

Query: 419 AELEAELEKLSLSEGGLVPSSKSP 442
               A +  +S     +VPS + P
Sbjct: 641 T---ASINPVSFQSSAMVPSMELP 661


>gi|109134355 NY-REN-58 antigen [Homo sapiens]
          Length = 701

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 94/444 (21%), Positives = 176/444 (39%), Gaps = 57/444 (12%)

Query: 7   EAEAPAGGDPAGLLPPEWEEDEERMSFLFSAF-KRSREVNSTDWDSKMGFWAPLVLSHSR 65
           EAE  +    A  L  E +   E+ +FL +   K  RE+N+     K        L HS 
Sbjct: 267 EAEKQSANLRAERLEKELQSSSEQNTFLINKLHKAEREINTLSSKVKE-------LKHSN 319

Query: 66  RQGVVRLRL---RDLQEAFQRKGSVPLGLATVLQDL-LRRGELQRESDFMASVDSSWISW 121
           +  +  ++L   R   E  + +  +   L  +  D  + +  ++     +   D   I  
Sbjct: 320 KLEITDIKLETARAKSELERERNKIQSELDGLQSDNEILKAAVEHHKVLLVEKDRELIR- 378

Query: 122 GVGVFLLKPLKWTLSNMLGDNKVPAEEVLVAVELLKEKAEEVYRLYQNSPLSSHPVVALS 181
              V   K   +    +L D K+  E  L  +E +K +  +V+R  +             
Sbjct: 379 --KVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVE-HDVWRQSEKDQYEEK------ 429

Query: 182 ELSTLCANSCPDERTFY-LVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVG 240
               L A+   +E T   L  ++L+ ++++  +E N EK        + ++S    + + 
Sbjct: 430 ----LRASQMAEEITRKELQSVRLKLQQQIVTIE-NAEKEKNENSDLKQQIS---SLQIQ 481

Query: 241 VYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKA-KQRTEKRIEALH 299
           V  L QSE  L    + L +  ER K+E    CR  + Q     L+A K   EK+I+ L 
Sbjct: 482 VTSLAQSENDLLNSNQMLKEMVERLKQE----CRNFRSQAEKAQLEAEKTLEEKQIQWLE 537

Query: 300 AKLDTVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQD 359
            K    + I DR    + +Q      +A +   K   K +   K + L ++++ L   ++
Sbjct: 538 EKHKLHERITDR--EEKYNQAKEKLQRAAIAQKK--RKSLHENKLKRLQEKVEVLEAKKE 593

Query: 360 EVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPD-NPRNRHFTNSVPNPRISD 418
           E            L+ +++ L ++ ++  +D T+    L D   R+  F + +  P +  
Sbjct: 594 E------------LETENQVLNRQ-NVPFEDYTRLQKRLKDIQRRHNEFRSLILVPNMPP 640

Query: 419 AELEAELEKLSLSEGGLVPSSKSP 442
               A +  +S     +VPS + P
Sbjct: 641 T---ASINPVSFQSSAMVPSMELP 661


>gi|21389505 janus kinase and microtubule interacting protein 1
           isoform 2 [Homo sapiens]
          Length = 626

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 52/215 (24%), Positives = 98/215 (45%), Gaps = 19/215 (8%)

Query: 193 DERTFYLVLLQLQK-----EKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVGVYQ---- 243
           D R F L + +L       E R T+L     +++K +R    ++ P+ + +  + +    
Sbjct: 286 DVRRFQLKIAELNSVIRKLEDRNTLLADERNELLKRSRETEVQLKPLVEKNKRMNKKNED 345

Query: 244 LMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLD 303
           L+QS Q +  K+++L++E    KE+   A  + K+  +L  L +  R E+ IE L  ++ 
Sbjct: 346 LLQSIQRMEEKIKNLTRENVEMKEKL-SAQASLKRHTSLNDL-SLTRDEQEIEFLRLQVL 403

Query: 304 TVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEK----AESLVDQIQELCDTQD 359
             Q ++D + + + ++++ +    G  +LK   K V VE      E  VD  + L +T  
Sbjct: 404 EQQHVIDDL-SLERERLLRSKRHRG-KSLKPPKKHV-VETFFGFDEESVDS-ETLSETSY 459

Query: 360 EVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKE 394
              +T     T   D D     +E D+     T+E
Sbjct: 460 NTDRTDRTPATPEEDLDDATAREEADLRFCQLTRE 494


>gi|150456473 janus kinase and microtubule interacting protein 1
           isoform 1 [Homo sapiens]
          Length = 831

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 52/215 (24%), Positives = 98/215 (45%), Gaps = 19/215 (8%)

Query: 193 DERTFYLVLLQLQK-----EKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVGVYQ---- 243
           D R F L + +L       E R T+L     +++K +R    ++ P+ + +  + +    
Sbjct: 286 DVRRFQLKIAELNSVIRKLEDRNTLLADERNELLKRSRETEVQLKPLVEKNKRMNKKNED 345

Query: 244 LMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLD 303
           L+QS Q +  K+++L++E    KE+   A  + K+  +L  L +  R E+ IE L  ++ 
Sbjct: 346 LLQSIQRMEEKIKNLTRENVEMKEKL-SAQASLKRHTSLNDL-SLTRDEQEIEFLRLQVL 403

Query: 304 TVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEK----AESLVDQIQELCDTQD 359
             Q ++D + + + ++++ +    G  +LK   K V VE      E  VD  + L +T  
Sbjct: 404 EQQHVIDDL-SLERERLLRSKRHRG-KSLKPPKKHV-VETFFGFDEESVDS-ETLSETSY 459

Query: 360 EVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKE 394
              +T     T   D D     +E D+     T+E
Sbjct: 460 NTDRTDRTPATPEEDLDDATAREEADLRFCQLTRE 494


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 61/291 (20%), Positives = 129/291 (44%), Gaps = 38/291 (13%)

Query: 141  DNKVPAEE----VLVAVELLKEKAEEVY-RLYQNSPLSSHPVVALSELSTLCANSCPDER 195
            +N + AEE    ++ +  LL+ K +E+  RL +   ++S  V     L   C++   D  
Sbjct: 900  ENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDID 959

Query: 196  TFYLVLLQLQKEK------------RVTVLEQNGEKIVKFARG-PRAKVSPVNDVDV--- 239
               L L +++KEK             +T LE+N  K+ K  +    A    ++D+ V   
Sbjct: 960  DLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEED 1019

Query: 240  ---GVYQLMQSEQLLSRKVESLSQEAERCKEEARRACR--AGKKQLALRSLKAKQRTEKR 294
               G+ ++    +  +  +E   ++ ++ + +  RA R   G  +++  S+   +  +++
Sbjct: 1020 KVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQ 1079

Query: 295  IEALHAKLDTVQGILDRIYASQTDQMVFN-AYQAGVGALKLSMKDVTVE-KAE-----SL 347
            IE    KL   +  L ++ A   D+ V +  +Q  +  L+  ++++  E +AE      +
Sbjct: 1080 IE---EKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKI 1136

Query: 348  VDQIQELCDTQDEVSQTL--AGGVTNGLDFDSEELEKELDILLQDTTKEPL 396
              Q  +L    +E+S+ L  A G T+     +++ E E   + +D  +  L
Sbjct: 1137 EKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATL 1187


>gi|14165274 golgi-associated microtubule-binding protein HOOK3
           [Homo sapiens]
          Length = 718

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 53/268 (19%), Positives = 112/268 (41%), Gaps = 43/268 (16%)

Query: 187 CANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVGV-YQLM 245
           CA +C  ++ +   ++ +++  +  V+    E + K      + VS  ND  V +  QL 
Sbjct: 125 CAVNCEQKQEYIQAIMMMEESVQHVVMTAIQELMSK-----ESPVSAGNDAYVDLDRQLK 179

Query: 246 QSEQLLSRKVESLSQEAERCKE--------EARRACRAGKKQLALRSLKAKQRTE----- 292
           ++ + L+  + +  + A+RC E        +  ++    + Q+ +  L      E     
Sbjct: 180 KTTEELNEALSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQSDSIEDPNSP 239

Query: 293 --KRIEALHAKLDTVQGILDRIYASQTDQMV-FNAYQAGVGALKLSMKDVTV--EKAESL 347
             +R   L  +L+ +Q    R+ A++ D  +     +  +  L+    ++T   ++A+SL
Sbjct: 240 AGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTTLADEAQSL 299

Query: 348 VDQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHF 407
            D+I  L  + D+VS+         L+   E  +K+L+ L     +  + L +     + 
Sbjct: 300 KDEIDVLRHSSDKVSK---------LEGQVESYKKKLEDL--GDLRRQVKLLEEKNTMYM 348

Query: 408 TNSVPNPRISDAELEAELEKLSLSEGGL 435
            N+V         LE EL K + +   L
Sbjct: 349 QNTV--------SLEEELRKANAARSQL 368


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 45/225 (20%), Positives = 99/225 (44%), Gaps = 28/225 (12%)

Query: 142  NKVPAEEVLVAVELLKEKAEEVYRLYQNSPLSSHPVVALSELSTLCANSCPDERTF-YLV 200
            NK  A+E+    ELLKEK +EV +L ++       + AL             ERT   L 
Sbjct: 2003 NKSHAKELQ---ELLKEKQQEVKQLQKDCIRYQEKISAL-------------ERTVKALE 2046

Query: 201  LLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSP----VNDVDVGVYQLMQSEQLLSRKVE 256
             +Q + +K + + ++N  + V+  +  +A+++     ++D      +++     L ++++
Sbjct: 2047 FVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2106

Query: 257  SLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQ 316
            S  +  +   ++         +Q   + LK K+  +++++AL  +   ++  +  I    
Sbjct: 2107 SNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEI---- 2162

Query: 317  TDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEV 361
              Q+  N     V  L+ ++ D TV +  +    +  L D +D V
Sbjct: 2163 --QVTLNKKDKEVQQLQENL-DSTVTQLAAFTKSMSSLQDDRDRV 2204


>gi|110815815 centlein isoform 1 [Homo sapiens]
          Length = 1406

 Score = 34.3 bits (77), Expect = 0.24
 Identities = 74/372 (19%), Positives = 143/372 (38%), Gaps = 60/372 (16%)

Query: 90   GLATVLQDLLRRGELQRESDFMASVDSSWISWGVGVFLLKP----------LKWTLSNML 139
            GL    +DLL++ E   E   +A  +S      + V  L P          L++ L N  
Sbjct: 1046 GLRKEKEDLLKKLESSSEITSLAEENSQVTFPRIQVTSLSPSRSMDLEMKQLQYKLKNAT 1105

Query: 140  GDN-------KVPAEEVLVAVELLKEKAEEVYRLYQNSPLSSHPVVALSELSTLCANSCP 192
             +        K    E+L   E +KE  E++ R+ ++  +  H +  L     +   S  
Sbjct: 1106 NELTKQSSNVKTLKFELLAKEEHIKEMHEKISRMERDITMKRHLIEDLKFRQKVNLES-- 1163

Query: 193  DERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVGVYQLMQSEQLLS 252
              ++F  +L  L K+ +    E + +K+   +   R        ++V V +  Q EQ+  
Sbjct: 1164 -NKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQR--------LNVAVKEKSQYEQMYQ 1214

Query: 253  RKVESLSQ-------------EAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALH 299
            +  E L +             E E    E   A     ++LAL+S +  +  +K +   +
Sbjct: 1215 KSKEELEKKDLKLTLLVSRISETESAMAEIETAASKQLQELALQSEQVLEGAQKTLLLAN 1274

Query: 300  AKLDTVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQD 359
             K++     +         + +    Q  V  ++  ++++   K        ++ C T  
Sbjct: 1275 EKVEEFTTFV---------KALAKELQNDVHVVRRQIRELKKMKKN------RDACKTST 1319

Query: 360  EVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRISDA 419
              +QTLA  + N    D EE+    D +  + TK  +D  ++     +   +   ++  A
Sbjct: 1320 HKAQTLAASILNISRSDLEEILDTEDQVEIEKTK--IDAENDKEWMLYIQKLLEGQLPFA 1377

Query: 420  E--LEAELEKLS 429
               LEA LEK++
Sbjct: 1378 SYLLEAVLEKIN 1389


>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
           b [Homo sapiens]
          Length = 882

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 55/251 (21%), Positives = 107/251 (42%), Gaps = 15/251 (5%)

Query: 201 LLQLQKE-KRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVGVYQLMQSEQLLSRKVESLS 259
           LL+ +KE ++   +    E  VK A+  ++K +    +   V +L  S +   ++    +
Sbjct: 279 LLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAA 338

Query: 260 QEAERCKEEARRA-CRAGKKQLALRS--LKAKQRTEKRIEALHAKLDTVQGILDRIYASQ 316
           Q+A +CKEEA  A C     Q  L+   L  KQ+ +  I+ L  +L  +Q         Q
Sbjct: 339 QQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKAD-TIQELQRELQMLQKESSMAEKEQ 397

Query: 317 TDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFD 376
           T     N  +    +L+LS     +E ++    Q+Q+    QD     +   + +    +
Sbjct: 398 TS----NRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIKH-QHRE 452

Query: 377 SEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRISDAELEAELEKLSLSEGGLV 436
              ++ +L+  LQ+ TK   D     +      S  + ++ + ELEA  ++    +  L 
Sbjct: 453 QGSIKCKLEEDLQEATKLLED-----KREQLKKSKEHEKLMEGELEALRQEFKKKDKTLK 507

Query: 437 PSSKSPKRQLE 447
            +S+  + + E
Sbjct: 508 ENSRKLEEENE 518


>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
           a [Homo sapiens]
          Length = 1007

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 55/251 (21%), Positives = 107/251 (42%), Gaps = 15/251 (5%)

Query: 201 LLQLQKE-KRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVGVYQLMQSEQLLSRKVESLS 259
           LL+ +KE ++   +    E  VK A+  ++K +    +   V +L  S +   ++    +
Sbjct: 424 LLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAA 483

Query: 260 QEAERCKEEARRA-CRAGKKQLALRS--LKAKQRTEKRIEALHAKLDTVQGILDRIYASQ 316
           Q+A +CKEEA  A C     Q  L+   L  KQ+ +  I+ L  +L  +Q         Q
Sbjct: 484 QQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKAD-TIQELQRELQMLQKESSMAEKEQ 542

Query: 317 TDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFD 376
           T     N  +    +L+LS     +E ++    Q+Q+    QD     +   + +    +
Sbjct: 543 TS----NRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIKH-QHRE 597

Query: 377 SEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRISDAELEAELEKLSLSEGGLV 436
              ++ +L+  LQ+ TK   D     +      S  + ++ + ELEA  ++    +  L 
Sbjct: 598 QGSIKCKLEEDLQEATKLLED-----KREQLKKSKEHEKLMEGELEALRQEFKKKDKTLK 652

Query: 437 PSSKSPKRQLE 447
            +S+  + + E
Sbjct: 653 ENSRKLEEENE 663


>gi|223005859 WD repeat domain 67 isoform 1 [Homo sapiens]
          Length = 1066

 Score = 33.5 bits (75), Expect = 0.41
 Identities = 45/211 (21%), Positives = 90/211 (42%), Gaps = 16/211 (7%)

Query: 162 EVYRLYQNSPLSSHPVVALSELSTLCANSCP--DERTFYLVLLQLQKEKRVTVLEQNGEK 219
           +VY L + +P   HP   L+    L     P  ++   ++V  Q Q+ +R+   E +  +
Sbjct: 645 QVYHLMETTPTDIHPDSMLNVFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLR 704

Query: 220 IVKFARGPRAKVSPVNDVDVGVYQLMQSEQLLSRKVES-----LSQEAERCKEEARRACR 274
             +     +AKV      D   YQ    +Q L RK E      L QE E+  ++ +R   
Sbjct: 705 ERQTVEDMQAKVDQQRVEDEAWYQ----KQELLRKAEETRREMLLQEEEKMIQQRQRLA- 759

Query: 275 AGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQTDQMVFNAYQAGVGALKL 334
           A K++L ++ +  +    +R   L  + D  +  L R+      ++     +    A  L
Sbjct: 760 AVKRELKVKEMHLQDAARRRF--LKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDL 817

Query: 335 SMKDVTVEKAESLVDQIQELCDTQDEVSQTL 365
            M+ + +E  + L +  + L + Q+ +++ +
Sbjct: 818 EMRQLELESQKRLYE--KNLTENQEALAKEM 846


>gi|39725952 angiogenic factor VG5Q [Homo sapiens]
          Length = 714

 Score = 33.5 bits (75), Expect = 0.41
 Identities = 43/188 (22%), Positives = 73/188 (38%), Gaps = 26/188 (13%)

Query: 251 LSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILD 310
           L RKVE L +E   CK + R       ++L   + +  Q  E   + L  +++ +  IL 
Sbjct: 25  LRRKVEKLERELRSCKRQVREI-----EKLLHHTERLYQNAESNNQELRTQVEELSKILQ 79

Query: 311 RIYASQTDQMVFNAYQAGVGALKLSMKDV---TVEKAESLVDQIQELCDTQDEVSQTLAG 367
           R      D    +           S+ D    T     SL +++ EL D QD+  +T   
Sbjct: 80  R--GRNEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNKVTELSDQQDQAIET--- 134

Query: 368 GVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNR---HFTNSVPNPRISDAELEAE 424
            + N  D           + +++      D  +N + R   HF ++   P  + A  +  
Sbjct: 135 SILNSKD----------HLQVENDAYPGTDRTENVKYRQVDHFASNSQEPASALATEDTS 184

Query: 425 LEKLSLSE 432
           LE  SL+E
Sbjct: 185 LEGSSLAE 192


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 33.1 bits (74), Expect = 0.53
 Identities = 43/209 (20%), Positives = 92/209 (44%), Gaps = 22/209 (10%)

Query: 147  EEVLVAVELLKEKAEEVYRLYQNSPLSSHPVVALSELSTLCANSCPDERTFYLVLLQLQK 206
            +EV+  +  L+ + ++  R  + +  S   + A S+ S     S   E      +LQLQ+
Sbjct: 1641 DEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAE------ILQLQE 1694

Query: 207  E-------KRVTVLEQN--GEKIVKFARGPRAKVSPVNDVDVGVYQLMQSEQLLSRKVES 257
            E       +R    E++   ++I   A G  A +     ++  + QL +  +     +E 
Sbjct: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 1754

Query: 258  LSQEAERC--KEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYAS 315
            L+    +   + +   A  A ++  A +S  A+Q+ E++ + L AKL  ++G +   +  
Sbjct: 1755 LNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKF-- 1812

Query: 316  QTDQMVFNAYQAGVGALKLSMKDVTVEKA 344
               +   +A +A +G L+  ++    E+A
Sbjct: 1813 ---KATISALEAKIGQLEEQLEQEAKERA 1838



 Score = 32.3 bits (72), Expect = 0.91
 Identities = 40/185 (21%), Positives = 82/185 (44%), Gaps = 33/185 (17%)

Query: 202  LQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVGVYQLMQSEQLLSRKVESLSQE 261
            LQ + +   T+LE+  +K +KFA+   +  S + D    + +  + +  LS ++  L +E
Sbjct: 1285 LQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEE 1344

Query: 262  AERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKL-DTVQGILDRIYASQTDQM 320
                +E+                 +A++  EK++ AL ++L DT + + D +        
Sbjct: 1345 KNSLQEQQE------------EEEEARKNLEKQVLALQSQLADTKKKVDDDL-------- 1384

Query: 321  VFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSEEL 380
                 ++   A K  +KD     AE+L  +++E     D++ +T      N L  + ++L
Sbjct: 1385 --GTIESLEEAKKKLLKD-----AEALSQRLEEKALAYDKLEKT-----KNRLQQELDDL 1432

Query: 381  EKELD 385
              +LD
Sbjct: 1433 TVDLD 1437


>gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]
          Length = 775

 Score = 33.1 bits (74), Expect = 0.53
 Identities = 44/181 (24%), Positives = 77/181 (42%), Gaps = 25/181 (13%)

Query: 147 EEVLVAVELLKEKAEEVYRLYQNSPLSSH---PVVALSELSTLCANSCPDERTFYLVLLQ 203
           EE  + V +LK+K E++ RL Q +   S     V  L +L  + ++   D        L 
Sbjct: 423 EESSLDVNVLKDKMEKLKRLLQVAARKSQVTLDVEKLCDLEIMPSSEAADGEK--ATALY 480

Query: 204 LQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVGVYQLMQS--EQLLSRKVESLS-- 259
            Q+E     L+Q  E+  ++    +  +   N  D  + + +++  EQL   K + +S  
Sbjct: 481 YQQE-----LKQLKEEFERYKMRAQVVLKSKNTKDGNLGKELEAAQEQLAELKEKYISLR 535

Query: 260 -----------QEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGI 308
                      QEA+  K+E  R  +  +++L    L  + RT K  E LH + D    +
Sbjct: 536 LSCEELEHQHQQEADDWKQELARLQQLHRQELERCQLDFRDRTLKLEEELHKQRDRALAV 595

Query: 309 L 309
           L
Sbjct: 596 L 596


>gi|45439327 periplakin [Homo sapiens]
          Length = 1756

 Score = 33.1 bits (74), Expect = 0.53
 Identities = 57/259 (22%), Positives = 107/259 (41%), Gaps = 36/259 (13%)

Query: 154  ELLKEKAEEVYRLYQNSPLSSHPVVALSELSTLCANSCPDERTFYLVLLQLQK------- 206
            E +  K EE+ R+ +   +    VV   E   L A +     +  + L Q+ K       
Sbjct: 1334 EQIARKEEELSRVKER--VVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRR 1391

Query: 207  -EKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVGVYQLMQSEQLLSRKVES-----LSQ 260
             ++R T LE+  E++ +  +  R     V  +   +  L Q E     KV       L Q
Sbjct: 1392 LQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQ 1451

Query: 261  EAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQG--ILDRIYASQTD 318
            + ++ +E A    +  ++Q        +Q  E  +E L  KL  ++   + +++  S++ 
Sbjct: 1452 DPQQAREHALLRLQLEEEQ------HRRQLLEGELETLRRKLAALEKAEVKEKVVLSESV 1505

Query: 319  QMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSE 378
            Q+     +  +  LK S+++ +  K E  V           EVS+  A    + L+F + 
Sbjct: 1506 QVEKGDTEQEIQRLKSSLEEESRSKRELDV-----------EVSRLEAR--LSELEFHNS 1552

Query: 379  ELEKELDILLQDTTKEPLD 397
            +  KELD L ++  K  L+
Sbjct: 1553 KSSKELDFLREENHKLQLE 1571


>gi|38570058 hypothetical protein LOC80129 [Homo sapiens]
          Length = 715

 Score = 32.7 bits (73), Expect = 0.69
 Identities = 42/185 (22%), Positives = 82/185 (44%), Gaps = 36/185 (19%)

Query: 206 KEKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVGVYQLMQSEQLLSRKVESLSQEAERC 265
           KE  +++L Q   KI +     +A+ + V + D     +      L +KVE L +E   C
Sbjct: 500 KELHMSLLRQ---KIAQLEEEKQARTALVVERDNAHLTIRN----LQKKVERLQKELNTC 552

Query: 266 KE--EARRACRAGKKQLALRSL-----------------KAKQRTEKRIEALHAKLDTVQ 306
           ++     +A  A   +L +++L                 K K++ EK++ ++ ++LDT +
Sbjct: 553 RDLHTELKAKLADTNELKIKTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTE 612

Query: 307 GILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLA 366
                  A +  +   N  +     +K   K  ++E+AE    + ++L D ++ VSQ L 
Sbjct: 613 H-----EAKENKERARNMIEVVTSEMKTLKK--SLEEAEK---REKQLADFREVVSQMLG 662

Query: 367 GGVTN 371
             VT+
Sbjct: 663 LNVTS 667


>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
           [Homo sapiens]
          Length = 1814

 Score = 32.7 bits (73), Expect = 0.69
 Identities = 53/222 (23%), Positives = 96/222 (43%), Gaps = 32/222 (14%)

Query: 201 LLQLQKEK-----RVTVLEQNGEKIVKFARGPRAKVSPVN-----DVDVGVYQLMQSEQL 250
           + +L+KE      R+  LE   E++ +   GP   +   N     +V+    +L + EQL
Sbjct: 67  ITELKKENFNLKLRIYFLE---ERMQQEFHGPTEHIYKTNIELKVEVESLKRELQEREQL 123

Query: 251 L---SRKVESLSQ----EAERCKEEARRACRAGKKQLALRSL---KAKQRTEKRIEALHA 300
           L   S+ VESL++    E +R KE+AR+  +  +  L  R L   K     +  +E   A
Sbjct: 124 LIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEKAFA 183

Query: 301 KLDTVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEK-------AESLVDQIQE 353
             +T + +  R+ +  ++    +     + AL L  KD  +E+        E+L+  ++E
Sbjct: 184 GTETEKALRLRLESKLSEMKKMHEGDLAM-ALVLDEKDRLIEELKLSLKSKEALIQCLKE 242

Query: 354 LCDTQDEVSQTLAGGVTNGL-DFDSEELEKELDILLQDTTKE 394
                    + ++ G   GL     EE E+E +    +  KE
Sbjct: 243 EKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKE 284


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,991,013
Number of Sequences: 37866
Number of extensions: 759761
Number of successful extensions: 2379
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 88
Number of HSP's that attempted gapping in prelim test: 2292
Number of HSP's gapped (non-prelim): 175
length of query: 453
length of database: 18,247,518
effective HSP length: 106
effective length of query: 347
effective length of database: 14,233,722
effective search space: 4939101534
effective search space used: 4939101534
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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