Guide to the Human Genome
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Search of human proteins with 226823235

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226823235 regenerating islet-derived family, member 4
isoform 2 [Homo sapiens]
         (134 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226823235 regenerating islet-derived family, member 4 isoform...   285   1e-77
gi|226823233 regenerating islet-derived family, member 4 isoform...   120   2e-28
gi|14042980 regenerating islet-derived family, member 4 isoform ...   120   2e-28
gi|38372935 brevican isoform 1 [Homo sapiens]                          34   0.031
gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]               32   0.12 
gi|169234653 NKG2-D type II integral membrane protein [Homo sapi...    32   0.12 
gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens]         32   0.12 
gi|30581160 ganglioside-induced differentiation-associated prote...    31   0.26 
gi|37577103 C-type lectin-like receptor-1 [Homo sapiens]               31   0.34 
gi|153252048 C-type lectin domain family 1, member B isoform b [...    30   0.44 
gi|153252029 C-type lectin domain family 1, member B isoform a [...    30   0.44 
gi|4502251 asialoglycoprotein receptor 1 [Homo sapiens]                30   0.44 
gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]               30   0.58 
gi|37675377 dendritic cell-associated C-type lectin 1 isoform d ...    30   0.58 
gi|13384604 dendritic cell-associated C-type lectin 1 isoform b ...    30   0.58 
gi|46409282 OTU domain containing 6A [Homo sapiens]                    30   0.58 
gi|187607300 versican isoform 2 [Homo sapiens]                         30   0.76 
gi|21361116 versican isoform 1 [Homo sapiens]                          30   0.76 
gi|111548660 hypothetical protein LOC345222 isoform a [Homo sapi...    29   0.99 
gi|111548657 hypothetical protein LOC345222 isoform b [Homo sapi...    29   0.99 
gi|4758844 nucleoporin 155kDa isoform 2 [Homo sapiens]                 29   1.3  
gi|24430149 nucleoporin 155kDa isoform 1 [Homo sapiens]                29   1.3  
gi|55741473 HECT, C2 and WW domain containing E3 ubiquitin prote...    29   1.3  
gi|7705574 killer cell lectin-like receptor subfamily F, member ...    28   1.7  
gi|55953106 phospholipase A2 receptor 1 isoform 2 precursor [Hom...    28   2.2  
gi|55953104 phospholipase A2 receptor 1 isoform 1 precursor [Hom...    28   2.2  
gi|4505501 oxidized low density lipoprotein (lectin-like) recept...    28   2.2  
gi|18426877 asialoglycoprotein receptor 2 isoform c [Homo sapiens]     28   2.2  
gi|18426875 asialoglycoprotein receptor 2 isoform b [Homo sapiens]     28   2.2  
gi|18426873 asialoglycoprotein receptor 2 isoform a [Homo sapiens]     28   2.2  

>gi|226823235 regenerating islet-derived family, member 4 isoform 2
           [Homo sapiens]
          Length = 134

 Score =  285 bits (728), Expect = 1e-77
 Identities = 134/134 (100%), Positives = 134/134 (100%)

Query: 1   MASRSMRLLLLLSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRNWSDAEVRNLL 60
           MASRSMRLLLLLSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRNWSDAEVRNLL
Sbjct: 1   MASRSMRLLLLLSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRNWSDAEVRNLL 60

Query: 61  PAWPGLSRAKDQPEPQISFDSGSSVLPGHYEEKPLWLVKWREEGCVFNSFNSVSIAEAGA 120
           PAWPGLSRAKDQPEPQISFDSGSSVLPGHYEEKPLWLVKWREEGCVFNSFNSVSIAEAGA
Sbjct: 61  PAWPGLSRAKDQPEPQISFDSGSSVLPGHYEEKPLWLVKWREEGCVFNSFNSVSIAEAGA 120

Query: 121 VCQTLDGLQAHTDT 134
           VCQTLDGLQAHTDT
Sbjct: 121 VCQTLDGLQAHTDT 134


>gi|226823233 regenerating islet-derived family, member 4 isoform
          1 [Homo sapiens]
          Length = 158

 Score =  120 bits (302), Expect = 2e-28
 Identities = 55/56 (98%), Positives = 56/56 (100%)

Query: 1  MASRSMRLLLLLSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRNWSDAEV 56
          MASRSMRLLLLLSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRNWSDAE+
Sbjct: 1  MASRSMRLLLLLSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRNWSDAEL 56


>gi|14042980 regenerating islet-derived family, member 4 isoform 1
          [Homo sapiens]
          Length = 158

 Score =  120 bits (302), Expect = 2e-28
 Identities = 55/56 (98%), Positives = 56/56 (100%)

Query: 1  MASRSMRLLLLLSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRNWSDAEV 56
          MASRSMRLLLLLSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRNWSDAE+
Sbjct: 1  MASRSMRLLLLLSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRNWSDAEL 56


>gi|38372935 brevican isoform 1 [Homo sapiens]
          Length = 911

 Score = 34.3 bits (77), Expect = 0.031
 Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 2/46 (4%)

Query: 14  CLAKTGVLGDI--IMRPSCAPGWFYHKSNCYGYFRKLRNWSDAEVR 57
           CL   G  GD+  +    C PGW   +  CY +F   R+W +AE +
Sbjct: 670 CLCLPGYGGDLCDVGLRFCNPGWDAFQGACYKHFSTRRSWEEAETQ 715


>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
          Length = 2416

 Score = 32.3 bits (72), Expect = 0.12
 Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 2/46 (4%)

Query: 14   CLAKTGVLGDI--IMRPSCAPGWFYHKSNCYGYFRKLRNWSDAEVR 57
            CL   G  G+   I +  C  GW  ++ +CY +F     W DAE R
Sbjct: 2188 CLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERR 2233


>gi|169234653 NKG2-D type II integral membrane protein [Homo
           sapiens]
          Length = 216

 Score = 32.3 bits (72), Expect = 0.12
 Identities = 9/26 (34%), Positives = 17/26 (65%)

Query: 30  CAPGWFYHKSNCYGYFRKLRNWSDAE 55
           C   W  +K+NCY +F + +NW +++
Sbjct: 99  CPKNWICYKNNCYQFFDESKNWYESQ 124


>gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens]
          Length = 1321

 Score = 32.3 bits (72), Expect = 0.12
 Identities = 12/26 (46%), Positives = 14/26 (53%)

Query: 30   CAPGWFYHKSNCYGYFRKLRNWSDAE 55
            C  GW   + +CY YF   R W DAE
Sbjct: 1088 CDRGWHKFQGHCYRYFAHRRAWEDAE 1113


>gi|30581160 ganglioside-induced differentiation-associated protein
           1-like 1 [Homo sapiens]
          Length = 367

 Score = 31.2 bits (69), Expect = 0.26
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 14/81 (17%)

Query: 54  AEVRNLLPA----WPGLSRAKDQPEPQISFDSGSSVLPGHYEEKPLWLVKWREEGCVFNS 109
           A   NL P     WP  +   D  +P  + D+  +  P H+  + L L  W +      S
Sbjct: 2   ATPNNLTPTNCSWWPISALESDAAKPAEAPDAPEAASPAHWPRESLVLYHWTQ------S 55

Query: 110 FNS----VSIAEAGAVCQTLD 126
           F+S    + IAE G VC+  D
Sbjct: 56  FSSQKVRLVIAEKGLVCEERD 76


>gi|37577103 C-type lectin-like receptor-1 [Homo sapiens]
          Length = 280

 Score = 30.8 bits (68), Expect = 0.34
 Identities = 8/26 (30%), Positives = 15/26 (57%)

Query: 30  CAPGWFYHKSNCYGYFRKLRNWSDAE 55
           C   W +H  NCY +++  ++W D +
Sbjct: 137 CTEQWKWHGDNCYQFYKDSKSWEDCK 162


>gi|153252048 C-type lectin domain family 1, member B isoform b
          [Homo sapiens]
          Length = 196

 Score = 30.4 bits (67), Expect = 0.44
 Identities = 9/26 (34%), Positives = 15/26 (57%)

Query: 30 CAPGWFYHKSNCYGYFRKLRNWSDAE 55
          C   W Y+  +CYG+FR    W +++
Sbjct: 69 CDTNWRYYGDSCYGFFRHNLTWEESK 94


>gi|153252029 C-type lectin domain family 1, member B isoform a
           [Homo sapiens]
          Length = 229

 Score = 30.4 bits (67), Expect = 0.44
 Identities = 9/26 (34%), Positives = 15/26 (57%)

Query: 30  CAPGWFYHKSNCYGYFRKLRNWSDAE 55
           C   W Y+  +CYG+FR    W +++
Sbjct: 102 CDTNWRYYGDSCYGFFRHNLTWEESK 127


>gi|4502251 asialoglycoprotein receptor 1 [Homo sapiens]
          Length = 291

 Score = 30.4 bits (67), Expect = 0.44
 Identities = 14/44 (31%), Positives = 22/44 (50%), Gaps = 1/44 (2%)

Query: 12  LSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRNWSDAE 55
           LSC     + G+   R  C   W  H+ +CY + R  + W+DA+
Sbjct: 137 LSC-QMAALQGNGSERTCCPVNWVEHERSCYWFSRSGKAWADAD 179


>gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]
          Length = 2317

 Score = 30.0 bits (66), Expect = 0.58
 Identities = 11/28 (39%), Positives = 15/28 (53%)

Query: 30   CAPGWFYHKSNCYGYFRKLRNWSDAEVR 57
            C  GW  ++ +CY +F     W DAE R
Sbjct: 2168 CEEGWNKYQGHCYRHFPDRETWVDAERR 2195


>gi|37675377 dendritic cell-associated C-type lectin 1 isoform d
          [Homo sapiens]
          Length = 143

 Score = 30.0 bits (66), Expect = 0.58
 Identities = 13/48 (27%), Positives = 24/48 (50%), Gaps = 1/48 (2%)

Query: 9  LLLLSCLAKTGVLGDI-IMRPSCAPGWFYHKSNCYGYFRKLRNWSDAE 55
          +L L  L    VLG + ++   C P W  ++ +CY +   L +W  ++
Sbjct: 52 ILCLVILVIAVVLGTMGVLSSPCPPNWIIYEKSCYLFSMSLNSWDGSK 99


>gi|13384604 dendritic cell-associated C-type lectin 1 isoform b
          [Homo sapiens]
          Length = 201

 Score = 30.0 bits (66), Expect = 0.58
 Identities = 13/48 (27%), Positives = 24/48 (50%), Gaps = 1/48 (2%)

Query: 9  LLLLSCLAKTGVLGDI-IMRPSCAPGWFYHKSNCYGYFRKLRNWSDAE 55
          +L L  L    VLG + ++   C P W  ++ +CY +   L +W  ++
Sbjct: 52 ILCLVILVIAVVLGTMGVLSSPCPPNWIIYEKSCYLFSMSLNSWDGSK 99


>gi|46409282 OTU domain containing 6A [Homo sapiens]
          Length = 288

 Score = 30.0 bits (66), Expect = 0.58
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 6/65 (9%)

Query: 62  AWPG------LSRAKDQPEPQISFDSGSSVLPGHYEEKPLWLVKWREEGCVFNSFNSVSI 115
           AW G      LS     P   I  DS + ++   Y +KP+ LV  R    +   +NSV+ 
Sbjct: 215 AWGGQLELRALSHVLKTPIEVIQADSPTLIIGEEYVKKPIILVYLRYAYSLGEHYNSVTP 274

Query: 116 AEAGA 120
            EAGA
Sbjct: 275 LEAGA 279


>gi|187607300 versican isoform 2 [Homo sapiens]
          Length = 655

 Score = 29.6 bits (65), Expect = 0.76
 Identities = 11/27 (40%), Positives = 13/27 (48%)

Query: 29  SCAPGWFYHKSNCYGYFRKLRNWSDAE 55
           +C  GW   +  CY YF   R W  AE
Sbjct: 427 TCDYGWHKFQGQCYKYFAHRRTWDAAE 453


>gi|21361116 versican isoform 1 [Homo sapiens]
          Length = 3396

 Score = 29.6 bits (65), Expect = 0.76
 Identities = 11/27 (40%), Positives = 13/27 (48%)

Query: 29   SCAPGWFYHKSNCYGYFRKLRNWSDAE 55
            +C  GW   +  CY YF   R W  AE
Sbjct: 3168 TCDYGWHKFQGQCYKYFAHRRTWDAAE 3194


>gi|111548660 hypothetical protein LOC345222 isoform a [Homo
          sapiens]
          Length = 278

 Score = 29.3 bits (64), Expect = 0.99
 Identities = 10/18 (55%), Positives = 14/18 (77%)

Query: 46 RKLRNWSDAEVRNLLPAW 63
          R+ RNW+DAE+R L+  W
Sbjct: 41 RRARNWTDAEMRGLMLVW 58


>gi|111548657 hypothetical protein LOC345222 isoform b [Homo
          sapiens]
          Length = 267

 Score = 29.3 bits (64), Expect = 0.99
 Identities = 10/18 (55%), Positives = 14/18 (77%)

Query: 46 RKLRNWSDAEVRNLLPAW 63
          R+ RNW+DAE+R L+  W
Sbjct: 41 RRARNWTDAEMRGLMLVW 58


>gi|4758844 nucleoporin 155kDa isoform 2 [Homo sapiens]
          Length = 1332

 Score = 28.9 bits (63), Expect = 1.3
 Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 11/98 (11%)

Query: 33  GWFYHKSNCYGYFRKLRNWSDAEVRNLLPAWPGLSRAKDQPEPQISFDSGSSVLPGHYEE 92
           GWF  +       RK+ N S + +  L+P+    + ++D P  QI+ D+  ++L    E+
Sbjct: 186 GWFSQRC------RKI-NHSKSSLSFLVPSLLQFTFSEDDPILQIAIDNSRNILYTRSEK 238

Query: 93  KPLWLVKWREEGCVFNSFNSVS----IAEAGAVCQTLD 126
             + +    ++G   +   SVS    ++ AG + +T+D
Sbjct: 239 GVIQVYDLGQDGQGMSRVASVSQNAIVSAAGNIARTID 276


>gi|24430149 nucleoporin 155kDa isoform 1 [Homo sapiens]
          Length = 1391

 Score = 28.9 bits (63), Expect = 1.3
 Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 11/98 (11%)

Query: 33  GWFYHKSNCYGYFRKLRNWSDAEVRNLLPAWPGLSRAKDQPEPQISFDSGSSVLPGHYEE 92
           GWF  +       RK+ N S + +  L+P+    + ++D P  QI+ D+  ++L    E+
Sbjct: 245 GWFSQRC------RKI-NHSKSSLSFLVPSLLQFTFSEDDPILQIAIDNSRNILYTRSEK 297

Query: 93  KPLWLVKWREEGCVFNSFNSVS----IAEAGAVCQTLD 126
             + +    ++G   +   SVS    ++ AG + +T+D
Sbjct: 298 GVIQVYDLGQDGQGMSRVASVSQNAIVSAAGNIARTID 335


>gi|55741473 HECT, C2 and WW domain containing E3 ubiquitin protein
           ligase 2 [Homo sapiens]
          Length = 1572

 Score = 28.9 bits (63), Expect = 1.3
 Identities = 15/32 (46%), Positives = 17/32 (53%)

Query: 60  LPAWPGLSRAKDQPEPQISFDSGSSVLPGHYE 91
           LPA P     +  PEPQ S D GS+ L G  E
Sbjct: 541 LPAGPAPEEGEGGPEPQPSADQGSAELCGSQE 572


>gi|7705574 killer cell lectin-like receptor subfamily F, member 1
           [Homo sapiens]
          Length = 231

 Score = 28.5 bits (62), Expect = 1.7
 Identities = 8/27 (29%), Positives = 16/27 (59%)

Query: 30  CAPGWFYHKSNCYGYFRKLRNWSDAEV 56
           C   W  ++  CY +  ++++WSD+ V
Sbjct: 114 CQSEWLKYQGKCYWFSNEMKSWSDSYV 140


>gi|55953106 phospholipase A2 receptor 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1324

 Score = 28.1 bits (61), Expect = 2.2
 Identities = 9/25 (36%), Positives = 14/25 (56%)

Query: 30  CAPGWFYHKSNCYGYFRKLRNWSDA 54
           C PGW  +  NCY   ++ + W +A
Sbjct: 378 CEPGWNPYNRNCYKLQKEEKTWHEA 402


>gi|55953104 phospholipase A2 receptor 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1463

 Score = 28.1 bits (61), Expect = 2.2
 Identities = 9/25 (36%), Positives = 14/25 (56%)

Query: 30  CAPGWFYHKSNCYGYFRKLRNWSDA 54
           C PGW  +  NCY   ++ + W +A
Sbjct: 378 CEPGWNPYNRNCYKLQKEEKTWHEA 402


>gi|4505501 oxidized low density lipoprotein (lectin-like) receptor
           1 [Homo sapiens]
          Length = 273

 Score = 28.1 bits (61), Expect = 2.2
 Identities = 27/131 (20%), Positives = 44/131 (33%), Gaps = 32/131 (24%)

Query: 30  CAPGWFYHKSNCYGYFRKLRNWSDAEVRNL--------------------------LPAW 63
           C   W +H  NCY +     NW  ++ + L                           P W
Sbjct: 144 CPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLLKINSTADLDFIQQAISYSSFPFW 203

Query: 64  PGLSRAKDQPEPQISFDSGSSVLPGHYEEKPLWLVKWREEGCVFNSFNSV----SIAEAG 119
            GLSR    P     ++ GS ++P  +  +      +    C +    +V     I  A 
Sbjct: 204 MGLSRR--NPSYPWLWEDGSPLMPHLFRVRGAVSQTYPSGTCAYIQRGAVYAENCILAAF 261

Query: 120 AVCQTLDGLQA 130
           ++CQ    L+A
Sbjct: 262 SICQKKANLRA 272


>gi|18426877 asialoglycoprotein receptor 2 isoform c [Homo sapiens]
          Length = 292

 Score = 28.1 bits (61), Expect = 2.2
 Identities = 9/29 (31%), Positives = 15/29 (51%)

Query: 27  RPSCAPGWFYHKSNCYGYFRKLRNWSDAE 55
           R  C   W  H+ +CY +    + W++AE
Sbjct: 155 RTCCPVNWVEHQGSCYWFSHSGKAWAEAE 183


>gi|18426875 asialoglycoprotein receptor 2 isoform b [Homo sapiens]
          Length = 287

 Score = 28.1 bits (61), Expect = 2.2
 Identities = 9/29 (31%), Positives = 15/29 (51%)

Query: 27  RPSCAPGWFYHKSNCYGYFRKLRNWSDAE 55
           R  C   W  H+ +CY +    + W++AE
Sbjct: 150 RTCCPVNWVEHQGSCYWFSHSGKAWAEAE 178


>gi|18426873 asialoglycoprotein receptor 2 isoform a [Homo sapiens]
          Length = 311

 Score = 28.1 bits (61), Expect = 2.2
 Identities = 9/29 (31%), Positives = 15/29 (51%)

Query: 27  RPSCAPGWFYHKSNCYGYFRKLRNWSDAE 55
           R  C   W  H+ +CY +    + W++AE
Sbjct: 174 RTCCPVNWVEHQGSCYWFSHSGKAWAEAE 202


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,667,524
Number of Sequences: 37866
Number of extensions: 248231
Number of successful extensions: 607
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 544
Number of HSP's gapped (non-prelim): 76
length of query: 134
length of database: 18,247,518
effective HSP length: 91
effective length of query: 43
effective length of database: 14,801,712
effective search space: 636473616
effective search space used: 636473616
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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