Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 226491199
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226491199 coiled-coil domain containing 38 [Homo sapiens]
(563 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226491199 coiled-coil domain containing 38 [Homo sapiens] 1093 0.0
gi|217272874 coiled-coil domain containing 37 [Homo sapiens] 272 5e-73
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 70 5e-12
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 60 5e-09
gi|71061468 centromere protein E [Homo sapiens] 60 7e-09
gi|221219020 NYD-SP11 protein [Homo sapiens] 59 9e-09
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 2e-08
gi|16262452 cingulin [Homo sapiens] 57 6e-08
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 55 1e-07
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 53 7e-07
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 53 8e-07
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 52 1e-06
gi|156104908 myosin heavy chain 6 [Homo sapiens] 52 1e-06
gi|31982906 cingulin-like 1 [Homo sapiens] 52 1e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 52 1e-06
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 52 1e-06
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 52 1e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 52 2e-06
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 52 2e-06
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 52 2e-06
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 52 2e-06
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 52 2e-06
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 50 4e-06
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 50 4e-06
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho... 50 4e-06
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho... 50 4e-06
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 50 6e-06
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 50 6e-06
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 50 6e-06
gi|148746195 trichohyalin [Homo sapiens] 50 7e-06
>gi|226491199 coiled-coil domain containing 38 [Homo sapiens]
Length = 563
Score = 1093 bits (2827), Expect = 0.0
Identities = 563/563 (100%), Positives = 563/563 (100%)
Query: 1 MSSNLLPTLNSGGKVKDGSTKEDRPYKIFFRDLFLVKENEMAAKETEKFMNRNMKVYQKT 60
MSSNLLPTLNSGGKVKDGSTKEDRPYKIFFRDLFLVKENEMAAKETEKFMNRNMKVYQKT
Sbjct: 1 MSSNLLPTLNSGGKVKDGSTKEDRPYKIFFRDLFLVKENEMAAKETEKFMNRNMKVYQKT 60
Query: 61 TFSSRMKSHSYLSQLAFYPKRSGRSFEKFGPGPAPIPRLIEGSDTKRTVHEFINDQRDRF 120
TFSSRMKSHSYLSQLAFYPKRSGRSFEKFGPGPAPIPRLIEGSDTKRTVHEFINDQRDRF
Sbjct: 61 TFSSRMKSHSYLSQLAFYPKRSGRSFEKFGPGPAPIPRLIEGSDTKRTVHEFINDQRDRF 120
Query: 121 LLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAA 180
LLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAA
Sbjct: 121 LLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAA 180
Query: 181 QETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKR 240
QETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKR
Sbjct: 181 QETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKR 240
Query: 241 AQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRT 300
AQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRT
Sbjct: 241 AQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRT 300
Query: 301 PEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYS 360
PEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYS
Sbjct: 301 PEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYS 360
Query: 361 QDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGE 420
QDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGE
Sbjct: 361 QDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGE 420
Query: 421 FNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKEN 480
FNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKEN
Sbjct: 421 FNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKEN 480
Query: 481 VEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSG 540
VEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSG
Sbjct: 481 VEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSG 540
Query: 541 NKQQLPLVNETKTKSQEEEYFFT 563
NKQQLPLVNETKTKSQEEEYFFT
Sbjct: 541 NKQQLPLVNETKTKSQEEEYFFT 563
>gi|217272874 coiled-coil domain containing 37 [Homo sapiens]
Length = 611
Score = 272 bits (696), Expect = 5e-73
Identities = 183/559 (32%), Positives = 296/559 (52%), Gaps = 35/559 (6%)
Query: 32 DLFLVKENEMAAKETEKFMNRNMKVYQKTTFSSRM--KSHSYLSQLAFYPKRSG------ 83
D FL+++ E +E+ + M+V+QK T+SS++ K S QL K+
Sbjct: 61 DFFLLRDQERNKALSERQQQKTMRVHQKMTYSSKVSAKHTSLRRQLQLEDKQEDLEARAE 120
Query: 84 ----RSFEKFGPGPAPIPRLIEGSDTKRTVHEFINDQRDRFLLEYALSTKRNTIKKFEKD 139
R+F + + + E + + +I +R FLL+YAL KR I++ E
Sbjct: 121 AEHQRAFRDYTTWKLTLTK--EKNVEPENMSGYIKQKRQMFLLQYALDVKRREIQRLETL 178
Query: 140 IAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAELKKASME 199
E +L++AEK L+ DA F+EF+REND SV A++ A +ET K++ E++ + +
Sbjct: 179 ATKEEARLERAEKSLEKDAALFDEFVRENDCSSVQAMRAAEKETKAKIEKILEIRDLTTQ 238
Query: 200 VQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPKILAKL 259
+ +KSEI++ E L+ Y Y FL ++SPK W +Q K + K+K K +
Sbjct: 239 IVNIKSEISRFEDTLKHYKVYKDFLYKLSPKEWLEEQEKKHSFLKKAKEVSEASKESSVN 298
Query: 260 SLHSSNKEGILEESGRTAVLSEDASQGRDSQGK--PSRSLTRTP----------EKKKSN 307
S GI G+ + + QG + + L R+P + +S+
Sbjct: 299 STPGDKGPGI---KGKASSMWAKEGQGTKKPWRFLQTMRLGRSPSYLSSPQQGSQPSESS 355
Query: 308 LAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENL 367
+S GS + +D EP LYF EP++LL V RELEEQNL+L Q SQ+ ++ L
Sbjct: 356 GGDSRGSNSPIPPTQEDTDSDGEEPQLYFTEPQQLLDVFRELEEQNLSLIQNSQETEKTL 415
Query: 368 EEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQE 427
EE++ K Q + + + L + + + +EE+ AAEL+LK+++F FGE+ D Q+
Sbjct: 416 EELSHTLKHTQIRMDREVNQLKQWVTTMMMSITKEEDTAAELELKARVFHFGEYKGDQQD 475
Query: 428 ILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERM 487
L++SL+ K+ VY+ C G ++ L +Q L +E +L EL + +E +P+ +E ER
Sbjct: 476 KLLESLNCKVLDVYRHCTGTQQEANLGTVQMLTIIEHQLDELLENLEHVPQVKIEQAERA 535
Query: 488 KQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSGN-KQQLP 546
K+KE R + R+EK++ ++ Q+E L+ A +A A+ KKK GR LV S+PP+ KQQ
Sbjct: 536 KEKERRIRLREEKLQMQKILQEEHLQRARARAQAEIKKKRGRTLVCRSRPPAHRIKQQ-- 593
Query: 547 LVNETKTKSQEEE--YFFT 563
T +EEE +FFT
Sbjct: 594 -SEHTLMDKEEEELLFFFT 611
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 70.1 bits (170), Expect = 5e-12
Identities = 117/546 (21%), Positives = 220/546 (40%), Gaps = 114/546 (20%)
Query: 122 LEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQ 181
LE ALST + T + K A + Q+K EK +++ ++ ++ L Q VD +K +++
Sbjct: 416 LEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSE 475
Query: 182 ETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGF------FLLQMSPKHWQIQ 235
E I KLQ E K+ + + Q + ++ E +E MK +L K Q
Sbjct: 476 EQIAKLQKLHE-KELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQES 534
Query: 236 QALKRAQASKSKANIILPKILAKLSLHSSN-KEGILE-ESGRTAVLSEDASQGRD----- 288
AL+ + K L L + + ILE ES L E+ +Q +D
Sbjct: 535 LALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHL 594
Query: 289 --SQGKPSRSLTRTPEKKKSNLAESFGSEDSL---------------------------E 319
+ K ++ +T EK K+ L +D+L E
Sbjct: 595 EAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKE 654
Query: 320 FLLDD----------EMDVDLEPALYFKEPE---------ELLQVLRELEEQNLTL---- 356
LL D EM+ L K+ E E+L+ +LEE+ L
Sbjct: 655 TLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQT 714
Query: 357 ---------------FQYSQDVDENLEE----VNKREKVIQDKTNSNIEFLLEQEKMLKA 397
+ Q VD ++E + + EK ++D+ N L E++K LK
Sbjct: 715 DKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKE 774
Query: 398 NCVREEEKAAEL--------QLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAE 449
+ E A++ Q +KL F + S E + +++ Q+ + + D E
Sbjct: 775 HQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHE-QTKAYEEQLAQLQQKLL-DLE 832
Query: 450 DDGLNPIQKLVKVESRLVELC-----------DLIESIPKENVEAIERMKQ--KEWRQKF 496
+ + +++ +VE++ ++C DL++ + K+N E +++K + + K
Sbjct: 833 TERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKL 892
Query: 497 RDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSGNKQQLPLVN---ETKT 553
D K++ Q +++ E + Q ++ + + ++ S + + ++N ETK
Sbjct: 893 ED---GNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKF 949
Query: 554 KSQEEE 559
K+QE++
Sbjct: 950 KNQEKK 955
Score = 52.0 bits (123), Expect = 1e-06
Identities = 98/466 (21%), Positives = 202/466 (43%), Gaps = 63/466 (13%)
Query: 115 DQRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVD 174
+Q++ LE K+ + + E + +++ + ++ + + E+ L+EN +S D
Sbjct: 530 EQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKD 589
Query: 175 -ALKMAAQETINKLQMTAELKKASMEVQAVK--SEIAKTEFLLREYMKYGFFLLQMSPKH 231
A+ + A++ + ++T ++K E++++K + TE L +Y + ++ K
Sbjct: 590 LAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKC 649
Query: 232 WQIQQALKRAQASKSKANI--ILPKILAKLSLHSSNKEGILEESGRTAV----LSEDASQ 285
Q ++ L + + +A+I + K L KL + + E + E L E+ S
Sbjct: 650 EQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSV 709
Query: 286 GRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVD-LEPALYFKEPEELLQ 344
+D K + L +++K++ + S + + E+ + E AL K+ L+
Sbjct: 710 LKDQTDKMKQELEAKMDEQKNHHQQQVDS-----IIKEHEVSIQRTEKAL--KDQINQLE 762
Query: 345 VLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEE 404
+L L+E++ L ++ V ENLE KR + + ++ ++ + EE
Sbjct: 763 LL--LKERDKHLKEHQAHV-ENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEE 819
Query: 405 KAAELQLK-----------SKLFSFGEFNS-------DAQEILIDSLS------------ 434
+ A+LQ K +K + E DA +I + L
Sbjct: 820 QLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQ 879
Query: 435 --KKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIES---IPKENVEAIE---R 486
K +TQVY+ + D + Q LV+ E+ ++++ + + I + + A E
Sbjct: 880 KVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIH 939
Query: 487 MKQKEWRQKFRD-----EKMKEKQRHQQERLKAALEKAVAQPKKKL 527
+ +E+ KF++ EK+K+K + QE LK L A+ KK+L
Sbjct: 940 ILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKEL 985
Score = 50.1 bits (118), Expect = 6e-06
Identities = 86/464 (18%), Positives = 187/464 (40%), Gaps = 58/464 (12%)
Query: 107 RTVHEFINDQRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLR 166
+T E + Q+D E K+ + EK +RE+ ++ E L+D + F+ +
Sbjct: 613 KTELESLKHQQDALWTEKLQVLKQQYQTEMEK---LREKCEQEKETLLKDKEIIFQAHIE 669
Query: 167 ENDQRSVDALKMAAQETINKLQMTAELKKA----SMEVQAVKSEIAKTEFLLREYMKYGF 222
E ++++++ L + E + +E+ KA E+ +K + K + L M
Sbjct: 670 EMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDE-- 727
Query: 223 FLLQMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEE-SGRTAVLSE 281
Q + Q+ +K + S + L + +L L ++ L+E L
Sbjct: 728 ---QKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEA 784
Query: 282 DASQGRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEE 341
D + + S L + + ++ E+ L L +D++ E L K+ E
Sbjct: 785 DIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAE 844
Query: 342 L----LQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKA 397
+ V EL+ + + Q +++ E+ ++ K + S +E ++++ K
Sbjct: 845 VEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQ 904
Query: 398 NCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQ 457
V +E +++ + Q+ I+ L++K++ A++D ++ +
Sbjct: 905 ILVEKENMILQMR-------------EGQKKEIEILTQKLS---------AKEDSIHILN 942
Query: 458 KLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALE 517
+ + E++ K + +E++KQK K E +K+K Q+ +LK LE
Sbjct: 943 E--EYETKF-----------KNQEKKMEKVKQKA---KEMQETLKKKLLDQEAKLKKELE 986
Query: 518 KA---VAQPKKKLGRRLVFHSKPPSGNKQQLPLVNETKTKSQEE 558
++Q +K+ +++ ++ S ET K Q E
Sbjct: 987 NTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIE 1030
Score = 50.1 bits (118), Expect = 6e-06
Identities = 78/438 (17%), Positives = 180/438 (41%), Gaps = 51/438 (11%)
Query: 124 YALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQET 183
+ L K N IK + DI + + +K+ + A E + + LK E
Sbjct: 1297 HQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASE-----KESCITQLKKELSEN 1351
Query: 184 INKLQ-MTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQ 242
IN + M ELK+ +E+ ++ ++ L+ + +S K I R Q
Sbjct: 1352 INAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNS-------ISLSEKEAAISSL--RKQ 1402
Query: 243 ASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPE 302
+ K ++ + + + S + LS++ + S + +
Sbjct: 1403 YDEEKCELL---------------DQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKK 1447
Query: 303 KKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQD 362
K +S + + L+ L+ L+ +++ E++ + EL++QN +
Sbjct: 1448 KAQSRFTQHQNTVKELQIQLE------LKSKEAYEKDEQINLLKEELDQQNKRFDCLKGE 1501
Query: 363 VDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFN 422
++++ ++ K+E ++ + S ++E E + +K E++ +++ +N
Sbjct: 1502 MEDDKSKMEKKESNLETELKSQTARIMELEDHI-------TQKTIEIESLNEVLK--NYN 1552
Query: 423 SDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPI-QKLVKVESRLVELCDLIESIPKENV 481
++I L +K+ + +G+ +D+ + +K++ +E+++ + +E+ KE
Sbjct: 1553 QQ-KDIEHKELVQKLQHFQE--LGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELE 1609
Query: 482 EAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSGN 541
+K KE K +++++ + + LK E+ +A KK+L ++ K
Sbjct: 1610 HVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQM--EEKEEQYK 1667
Query: 542 KQQLPLVNETKTKSQEEE 559
K ++E TK QE E
Sbjct: 1668 KGTESHLSELNTKLQERE 1685
Score = 43.9 bits (102), Expect = 4e-04
Identities = 82/480 (17%), Positives = 199/480 (41%), Gaps = 59/480 (12%)
Query: 106 KRTVHEFINDQRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFL 165
K + + + + ++ L TK+ ++ + +E +LK E +L+ ++ A L
Sbjct: 1581 KEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAEL 1640
Query: 166 RENDQRSVDALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLL 225
+ ++ + A+K ++ +++++ E K E S +++ L+E + L
Sbjct: 1641 KRKAEQKIAAIK---KQLLSQMEEKEEQYKKGTE-----SHLSELNTKLQEREREVHIL- 1691
Query: 226 QMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQ 285
++ LK ++S+S+ +I+P+ ++ ++ +E + E S
Sbjct: 1692 ---------EEKLKSVESSQSE-TLIVPRSAKNVAAYTEQEEAD-SQGCVQKTYEEKISV 1740
Query: 286 GRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLL------------DDEMDVDLEPA 333
+ + + + L R ++K+ ++ F + L D M L+
Sbjct: 1741 LQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEE 1800
Query: 334 LYFKEPEELLQVLRELEEQ--------NLTLFQYSQDVDENLEEVNKREKVIQDKTNSNI 385
L K + L V + +E++ L DV + L+E ++++ K
Sbjct: 1801 LEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELD 1860
Query: 386 EFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCI 445
L+ Q+++ + K +LQ ++ + +E + + Q +
Sbjct: 1861 SCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSN 1920
Query: 446 GDAEDDGL-----NPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEK 500
+A+ + L ++ K+ +V L + + KE+ + +E +K KE+ Q+ R+EK
Sbjct: 1921 MEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILK-KEYDQE-REEK 1978
Query: 501 MKEKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSGNKQQLPL-VNETKTKSQEEE 559
+K++Q + + + L++ + + +L ++ +Q+L + + ET K+QE E
Sbjct: 1979 IKQEQEDLELKHNSTLKQLMREFNTQLAQK-----------EQELEMTIKETINKAQEVE 2027
Score = 35.4 bits (80), Expect = 0.14
Identities = 68/313 (21%), Positives = 128/313 (40%), Gaps = 46/313 (14%)
Query: 144 ERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAELKKASMEVQAV 203
E+Q + E+K++ +E L + ++ ++ ++ LQM KK E++ +
Sbjct: 871 EKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKK---EIEIL 927
Query: 204 KSEIAKTE---FLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANII----LPKIL 256
+++ E +L E +Y K +++Q K Q + K + L K L
Sbjct: 928 TQKLSAKEDSIHILNE--EYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKEL 985
Query: 257 AKLSLHSSNKEG-----ILEES-GRTAVLSEDASQGRDSQGKPSRSLTRTP--------- 301
+L S KE +LE + +A +S+ S+ +Q + SLT
Sbjct: 986 ENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVIS 1045
Query: 302 --EKKKSNLAESFGSEDSLEFLLDDEMDVDLEPA--LYFKEPEELLQVLRELEE----QN 353
EKK + AE ++ ++ +L+ L+ E EE+ + + L+E Q+
Sbjct: 1046 IWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQD 1105
Query: 354 LTLFQYSQDVDENLEEVNKR-----------EKVIQDKTNSNIEFLLEQEKMLKANCVRE 402
TL + + + + VN EK+ D S E QE++++ + E
Sbjct: 1106 TTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAE 1165
Query: 403 EEKAAELQLKSKL 415
E+K +L SKL
Sbjct: 1166 EDKRKVSELTSKL 1178
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 60.1 bits (144), Expect = 5e-09
Identities = 81/371 (21%), Positives = 159/371 (42%), Gaps = 57/371 (15%)
Query: 182 ETINKLQMTAELKK--ASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALK 239
E N LQ +LK+ A +E + K++ EF + L Q+S K + LK
Sbjct: 1834 EINNYLQQIDQLKERIAGLEEEKQKNK----EFSQTLENEKNTLLSQISTKDGE----LK 1885
Query: 240 RAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTR 299
Q +K N++ + I EE R L E A + +D
Sbjct: 1886 MLQEEVTKMNLL--------------NQQIQEELSRVTKLKETAEEEKDD---------- 1921
Query: 300 TPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQY 359
E+ + LAE GS + D D ++ L E + L + + ELEE+ L +
Sbjct: 1922 LEERLMNQLAELNGSIGNY---CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKE 1978
Query: 360 SQDVD-----ENLEEVNKREKVIQDKTNSN-IEFLLEQE----KMLKANCVREEEKAAEL 409
V+ E LE++ +K +K+++ ++ LL+++ K L+ +C+R +EK + L
Sbjct: 1979 KTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISAL 2038
Query: 410 QLKSKLFSFGEFNSDAQ-EILIDSLSKKITQ---------VYKVCIGDAEDDGLNPIQKL 459
+ K F + S EI ++L++ + +KV + D + + +
Sbjct: 2039 ERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADN 2098
Query: 460 VKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKA 519
+K++ L + ++S K+ E +ER ++ + +++K +++ R K LE+
Sbjct: 2099 LKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEET 2158
Query: 520 VAQPKKKLGRR 530
+ + + L ++
Sbjct: 2159 IGEIQVTLNKK 2169
Score = 43.5 bits (101), Expect = 5e-04
Identities = 110/501 (21%), Positives = 198/501 (39%), Gaps = 99/501 (19%)
Query: 101 EGSDTKRTVHEFINDQRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALA 160
E S+ + + EF + + ALS +R+ + K+++M +L+ K+L+ + LA
Sbjct: 717 EISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSM-VTELRAQVKQLEMN-LA 774
Query: 161 FEEFLRENDQRSVDALKMAAQETINKLQMTAELKKASMEV-----QAVKSEIAKTEFLLR 215
E R D S A E I+ L + A+ K +EV V+ + ++ L+R
Sbjct: 775 EAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIR 834
Query: 216 EYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGR 275
Q+ K ++ + +R + SK L + L++ L + + +L E R
Sbjct: 835 SLQS------QLQNKESEVLEGAERVRHISSKVEE-LSQALSQKELEITKMDQLLLEKKR 887
Query: 276 TAVLSEDASQGRDSQ-----------------------------GKPSRSLTRTPEKKKS 306
+ + +D Q + L+R E KK
Sbjct: 888 DVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKE 947
Query: 307 NLAESFGSEDSLEFLLDD--------EMDVDLEPALYFKEPE--------------ELLQ 344
+ E L+ D+ + ++ E L KE E ELLQ
Sbjct: 948 QVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQ 1007
Query: 345 VLRELEEQNLTLFQYSQ-----------DVDENLEEVNKREKVIQDKTNSNIEFLLEQ-- 391
+ LEE+ L S+ +V+E+ E EK + K IE L+Q
Sbjct: 1008 RVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQE-IEIYLKQTI 1066
Query: 392 -EKMLKANCVR---EEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQ----VYKV 443
EK ++ +R EE+ AAE Q ++ + + D ID L +I++ + K+
Sbjct: 1067 SEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTN-QIDLLQAEISENQAIIQKL 1125
Query: 444 CIG--DAED-DGLNPIQKLVKV--------ESRLVELCDLIESIPKENVEAIERMKQKEW 492
DA D D + +++ V + E EL + I ++ KE + +++++
Sbjct: 1126 ITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALT 1185
Query: 493 RQKFRDEKMKEKQRHQQERLK 513
+K +K +EK+RH +E LK
Sbjct: 1186 SRKAILKKAQEKERHLREELK 1206
Score = 43.1 bits (100), Expect = 7e-04
Identities = 105/519 (20%), Positives = 202/519 (38%), Gaps = 61/519 (11%)
Query: 35 LVKENEMAAKETEKFMNRNMKVYQKTTFSSRMKSHSYLSQLAFYPKRSGRSF-EKFGPGP 93
L +NE A + + ++ QK+ S+ + L Q + S SF + + G
Sbjct: 406 LQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQ---HETASQTSFPDVYNEGT 462
Query: 94 APIPRLIEGSDTKRTVHEFINDQRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKK 153
+ S KR V E N++ L L + +K I + E Q + E
Sbjct: 463 QAVTEENIASLQKRVV-ELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEAD 521
Query: 154 LQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKTEFL 213
+ ++ + + + ++ + + T + Q EL +E++ + EIA
Sbjct: 522 REVSEISIVDIANKRSSSAEESGQDVLENTFS--QKHKELSVLLLEMKEAQEEIA----- 574
Query: 214 LREYMKYGFFLLQMSPKHWQI--QQALKRAQASKSKANIILPKILAKLSLHSSNKEGIL- 270
F LQ+ K + + L + + + + I P I K+ L + ++ L
Sbjct: 575 --------FLKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAP-IKMKVFLEDTGQDFPLM 625
Query: 271 --EESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESFGS-----------EDS 317
EES AV E AS S+ SL + KS + S +D
Sbjct: 626 PNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDE 685
Query: 318 LEFLLDDEMDVDLEPALYFKEPEELLQV-----LRELEEQNLTLFQYSQDVDENLEEVN- 371
LE L ++++L F + +E+ + +E+ N + ++ ++ D N
Sbjct: 686 LERLKSQILELELN----FHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTA 741
Query: 372 ---KREKVI-QDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQE 427
+R++++ Q K S + L Q K L+ N + E E+ L +S+
Sbjct: 742 LSEERDQLLSQVKELSMVTELRAQVKQLEMN-LAEAERQRRLDYESQTAHDNLLTEQIHS 800
Query: 428 ILIDSLSKKI------TQVYKVCIGDAEDDGL--NPIQKLVKVESRLVELCDLIESIPKE 479
+ I++ SK + ++ V + +E L + +L ES ++E + + I +
Sbjct: 801 LSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSK 860
Query: 480 NVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEK 518
E + + QKE D+ + EK+R E L+ +E+
Sbjct: 861 VEELSQALSQKELEITKMDQLLLEKKR-DVETLQQTIEE 898
Score = 42.7 bits (99), Expect = 9e-04
Identities = 69/346 (19%), Positives = 138/346 (39%), Gaps = 34/346 (9%)
Query: 116 QRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDA 175
+ D L LS K + K + +I +E +K +L+ A +E+D+R +
Sbjct: 1405 EEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQA-------KEHDER-IKQ 1456
Query: 176 LKMAAQETINKLQMTAELKKASMEVQA-VKSEIAKTEFLLREYMKYGFFLLQMSPKHWQI 234
L++ E K + E +A ++Q +++ + + L+E L ++
Sbjct: 1457 LQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERL 1516
Query: 235 QQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPS 294
++L ++ S N +L +L+L ++ ++ E R+ + ++ S +S
Sbjct: 1517 TKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLAL 1576
Query: 295 RSLTRTPEK--------KKSNLAESFGSEDS-------LEFLLDDEMDVDLEPA------ 333
LT EK K S +AES ++ E LL +V E
Sbjct: 1577 EGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVV 1636
Query: 334 -LYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQE 392
+E +EL LR E + Q+ ++ +EE+ ++ + I L E+
Sbjct: 1637 EAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEEN 1696
Query: 393 KMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILI--DSLSKK 436
L+A + A E +++ L S + + + + ++LSKK
Sbjct: 1697 DRLRAEVHPAGDTAKEC-METLLSSNASMKEELERVKMEYETLSKK 1741
Score = 40.8 bits (94), Expect = 0.003
Identities = 85/423 (20%), Positives = 176/423 (41%), Gaps = 45/423 (10%)
Query: 103 SDTKRTVHEFINDQRDRFLLEYALSTKR-------NTIKKFEKDIAMRERQLKKAEKKLQ 155
S + T H + + Q + LE L + + N+++K ++ E +++ E +Q
Sbjct: 2291 SQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQ 2350
Query: 156 DDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKTEFLLR 215
+ ++E+ E D ++ L E IN + + S + +A++ IA
Sbjct: 2351 NSKFSYEQL--ETDLQASRELTSRLHEEINMKEQKI-ISLLSGKEEAIQVAIA------- 2400
Query: 216 EYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGR 275
++ +H + + L+ + + + NI+L + K + +K L E+ +
Sbjct: 2401 ----------ELRQQHDKEIKELENLLSQEEEENIVLEEENKK----AVDKTNQLMETLK 2446
Query: 276 TAVLSEDASQGR--DSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPA 333
T + E+ Q DS K SL ++ + + E L +L+ + + A
Sbjct: 2447 T-IKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQL--EERHLSIILEKDQLIQEAAA 2503
Query: 334 LYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEK 393
K EE+ + +++ N + ++ + E++N+ + + +E L+Q K
Sbjct: 2504 ENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNK 2563
Query: 394 MLKANCVREEEKAAELQLKSKLF--SFGEFNSDAQEIL--IDSLSKKITQVYKVCIGDAE 449
L+ + EEK E + ++ SF + Q++ I+SL I+Q+ + E
Sbjct: 2564 ELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQE 2623
Query: 450 DDGLNPIQKLVKV-ESRLVELCDLIESIPKENVEAIERM--KQKEWRQKFR--DEKMKEK 504
+ L +KV E + L L S K E E + QKE +K ++K+K++
Sbjct: 2624 EGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKE 2683
Query: 505 QRH 507
+H
Sbjct: 2684 LKH 2686
Score = 39.3 bits (90), Expect = 0.010
Identities = 88/475 (18%), Positives = 191/475 (40%), Gaps = 77/475 (16%)
Query: 116 QRDRFLLEYALSTKRNTIKKFE-------KDIAMRERQLKKA---EKKLQDDALAFEEFL 165
Q+D + +S T+K E KD+ + + L +A KK Q + +F+ L
Sbjct: 2025 QKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLL 2084
Query: 166 RENDQRSV----DALKMAAQETINKLQMTAELKKASMEVQ------------AVKSEIAK 209
+ + D LK+ + NK + +++K+ +++ K+ K
Sbjct: 2085 DDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEK 2144
Query: 210 TEFLLREYM----KYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSN 265
+ L RE + G + ++ K ++QQ + ++ ++ L +S +
Sbjct: 2145 LDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQ----LAAFTKSMSSLQDD 2200
Query: 266 KEGILEESGRTAVLSEDASQGRDSQGK-----------PSRSLTRTPEKKKSNLA----- 309
++ +++E+ + DA Q ++ + + R ++ E+ K N++
Sbjct: 2201 RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHD 2260
Query: 310 -ESFGSEDSLEFLLDDEMDVDLEPA-------------LYFKEPEELLQVLRELEEQNLT 355
+ + S+ E L ++ L+ LY EL ++ EL+
Sbjct: 2261 KQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQ 2320
Query: 356 LFQYSQDVDENLEEVNKREKVI--QDKTNSNIEFLLEQ-EKMLKANCVREEEKAAELQLK 412
L S +++ E+ E +I Q+ N +F EQ E L+A+ E+ +K
Sbjct: 2321 LTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMK 2380
Query: 413 -SKLFSFGEFNSDAQEILIDSL----SKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLV 467
K+ S +A ++ I L K+I ++ + + E++ + ++ K +
Sbjct: 2381 EQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENL-LSQEEEENIVLEEENKKAVDKTN 2439
Query: 468 ELCDLIESIPKENVEAIERM----KQKEWRQKFRDEKMKEKQRHQQERLKAALEK 518
+L + +++I KEN++ ++ K Q RD + + Q+ ++ L LEK
Sbjct: 2440 QLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEK 2494
Score = 32.7 bits (73), Expect = 0.91
Identities = 70/332 (21%), Positives = 131/332 (39%), Gaps = 41/332 (12%)
Query: 113 INDQRDRFLLEYALS---TKRNTIKKFEK---DIAMRERQLKKAEKKLQDDALAFEEFLR 166
+N +RD L E A S T+ N++ EK + ++ QL +L+D + F +
Sbjct: 2777 LNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSK 2836
Query: 167 ----------------ENDQRSVDALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKT 210
E ++S + + +A + LKKA +Q + + K
Sbjct: 2837 AMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKE 2896
Query: 211 -EFLLREYMKYGFFLLQMSPKHWQIQQ------ALKRAQASKSKANIILPKILAKLSLHS 263
+ L ++Y++ + ++ P Q+Q+ A + Q + N+ L +L +
Sbjct: 2897 LKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEK 2956
Query: 264 SNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSN---LAESFGSEDSLEF 320
S+ E I E + L A +D Q ++L R S L + + S E
Sbjct: 2957 SSWE-IHERRMKEQYLM--AISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPET 3013
Query: 321 LLDDEMDVDLEPALYFKE--PEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQ 378
+ +L +Y E +L L+E+ ++ L + Q + + + LEE N +
Sbjct: 3014 SASPDGSQNL---VYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLC 3070
Query: 379 DKTNSNIEFLLEQEKMLKANCVREEEKAAELQ 410
D + S E +L +C E++ ELQ
Sbjct: 3071 DTSQSLRENQQHYGDLLN-HCAVLEKQVQELQ 3101
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 59.7 bits (143), Expect = 7e-09
Identities = 93/427 (21%), Positives = 186/427 (43%), Gaps = 43/427 (10%)
Query: 96 IPRLIEGSDTKRTVHEFINDQRDRF-LLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKL 154
I R +E + + VH + + ++ L +S K N I +KD+ LK + K+
Sbjct: 1713 ITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKI 1772
Query: 155 QDDALAFEEFLRENDQRSVDALKMAAQETINKL-QMTAELKKASMEVQAVKSEIAKTEFL 213
Q++ L+E Q ++D L+ E +KL M +L+ ++ ++Q E+ E
Sbjct: 1773 QEELRIAHMHLKE-QQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQ 1831
Query: 214 LREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEES 273
L K + + Q+++ +K + SK I + KL + + +++E
Sbjct: 1832 LITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKE- 1890
Query: 274 GRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPA 333
RD+ + +L ++ K +L E+ D E+ +L+ A
Sbjct: 1891 -------------RDNLRRVEETLKLERDQLKESLQETKAR--------DLEIQQELKTA 1929
Query: 334 -LYFKEPEELLQVLRE-LEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQ 391
+ KE +E + LRE + E+ + + +D+D++ +E+ K+ IQ+ ++ L
Sbjct: 1930 RMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKK---IQELQKKELQLL--- 1983
Query: 392 EKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDS--LSKKITQ-VYKVCIGDA 448
+K + +K E++ K F N Q + +D+ L+KK+ + + ++ I
Sbjct: 1984 --RVKEDVNMSHKKINEMEQLKK--QFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAK 2039
Query: 449 EDDGLNPIQKLVKVESRLVELCDLIESI--PKENVEAIERMKQKEWRQKFRDEKMKEKQR 506
E D L I++ +K+E R + L E I ++N + + Q+ E ++EK
Sbjct: 2040 ERDELRRIKESLKME-RDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCS 2098
Query: 507 HQQERLK 513
+E LK
Sbjct: 2099 RIKELLK 2105
Score = 42.7 bits (99), Expect = 9e-04
Identities = 102/500 (20%), Positives = 196/500 (39%), Gaps = 67/500 (13%)
Query: 93 PAPIPRLIEGSDTKRTVHEFINDQRDRFLLEYALSTKR-----NTIKKFEKDIAMRERQL 147
P+ + RL + K I ++D+ E R I K + D+A +
Sbjct: 753 PSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNY 812
Query: 148 KKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAELKKASMEVQAVKSEI 207
K +++ Q+ +F + + ++ + QE +N ++ E +K + A+K+E+
Sbjct: 813 KSTDQEFQNFKTLHMDF-EQKYKMVLEENERMNQEIVN---LSKEAQKFDSSLGALKTEL 868
Query: 208 A-KTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNK 266
+ KT+ ++ K ++Q+ L + K + L + L K
Sbjct: 869 SYKTQ--------------ELQEKTREVQERLNEMEQLKEQ----LENRDSTLQTVEREK 910
Query: 267 EGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESFGSE--------DSL 318
I E+ +T + +Q +D + SL ++ KS++ ++ ++L
Sbjct: 911 TLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNAL 970
Query: 319 EFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQ-----DVDENLEEVNKR 373
E L + ++ L K EE+ + L E T ++ Q D ++LE N +
Sbjct: 971 ESLKQHQETIN---TLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQ 1027
Query: 374 EKVIQDKTNSNIE-----FLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQE- 427
K N IE F L QEK + + E A + QLK+ L E + QE
Sbjct: 1028 TLTADVKDNEIIEQQRKIFSLIQEKN-ELQQMLESVIAEKEQLKTDLKENIEMTIENQEE 1086
Query: 428 --ILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIE 485
+L D L K+ V A++ +K E L CD + + ++ E +
Sbjct: 1087 LRLLGDELKKQQEIV-------AQEKN-----HAIKKEGELSRTCDRLAEVEEKLKEKSQ 1134
Query: 486 RMKQKEWRQKFRDEKMKEKQR--HQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSGNKQ 543
++++K+ + E+M E Q+ ++ E LK L+ + RL K ++
Sbjct: 1135 QLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEE 1194
Query: 544 QLPLVNETKTKSQEEEYFFT 563
+ E K + ++ F T
Sbjct: 1195 VKSITKERKVLKELQKSFET 1214
Score = 39.7 bits (91), Expect = 0.007
Identities = 80/429 (18%), Positives = 174/429 (40%), Gaps = 82/429 (19%)
Query: 126 LSTKRNTIKKFEKDIAMRERQ------LKKAEKKLQDDALAFEEFLRENDQRSVDALKMA 179
L + TI + + ++ + Q L+K+ KLQ++ E +Q + +K
Sbjct: 1244 LKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHE-----EQELLPNVKEV 1298
Query: 180 A--QETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQA 237
+ QET+N+L++ E + E+ + L ++ + + ++ + ++
Sbjct: 1299 SETQETMNELELLTEQSTTKDSTTLARIEMERLR-LNEKFQESQEEIKSLTKERDNLKTI 1357
Query: 238 LKRAQASKSKANIILPKILAKLSLHSSNKEGIL----EESGRTAVLSEDASQGRDSQGKP 293
+ + + + + LAK+ S +E L +++ T ++SE Q KP
Sbjct: 1358 KEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEM------EQFKP 1411
Query: 294 SRSLTRTPEKKKSNLAESFG-SEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRE---- 348
S E + L++ S D ++ + ++ D+ + E ++L + ++E
Sbjct: 1412 KDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAK 1471
Query: 349 --------------LEEQNLTLFQYSQDVDENLEEVN---KREKVIQDKTNSNIEFLLEQ 391
L+EQ T+ + ++ E E++ K+ + I DK + I+ + E+
Sbjct: 1472 HLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEK 1531
Query: 392 EKMLKANCVRE-EEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAED 450
E+ + E +EK EL+ F E A+D
Sbjct: 1532 EEQFNIKQISEVQEKVNELK------QFKEHRK------------------------AKD 1561
Query: 451 DGLNPIQ-KLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQ 509
L I+ K++++ +RL E + I+ + KE E MK+ + + +++KE +
Sbjct: 1562 SALQSIESKMLELTNRLQESQEEIQIMIKEK----EEMKRVQEALQIERDQLKENTKEIV 1617
Query: 510 ERLKAALEK 518
++K + EK
Sbjct: 1618 AKMKESQEK 1626
Score = 29.6 bits (65), Expect = 7.7
Identities = 48/214 (22%), Positives = 86/214 (40%), Gaps = 27/214 (12%)
Query: 321 LLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDK 380
++++ + + A KE E Q L+ L+E+N LF+ Q + +L + QD
Sbjct: 2310 IMNESTEFEERSATISKEWE---QDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDN 2366
Query: 381 TNSNIEFLLEQ---EKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKI 437
N ++ Q EK+ + E K + + +SK+ + + +I L K+
Sbjct: 2367 KNPHVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKM-QKELEVTNDIIAKLQAKV 2425
Query: 438 TQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFR 497
+ K L K + + L D + K E IE +K K K
Sbjct: 2426 HESNKC---------------LEKTKETIQVLQDKVALGAKPYKEEIEDLKMK--LVKID 2468
Query: 498 DEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRL 531
EKMK + ++E + KA + +K++ R L
Sbjct: 2469 LEKMKNAKEFEKE---ISATKATVEYQKEVIRLL 2499
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 59.3 bits (142), Expect = 9e-09
Identities = 100/447 (22%), Positives = 192/447 (42%), Gaps = 51/447 (11%)
Query: 110 HEFINDQRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLREND 169
H++ R R E + + + + E+ +A ERQL + E+KL A A+ + + ++D
Sbjct: 1572 HKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKL---AQAYVK-ITQDD 1627
Query: 170 QRSVDALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKT-EFLLREYMKYGFFLLQMS 228
+ A AQ+ Q +L + + ++ + ++AK E + RE K ++
Sbjct: 1628 REMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEK-------LA 1680
Query: 229 PKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRD 288
K ++ + +K A K + LP+ L LEE L D +
Sbjct: 1681 KKGGKLAE-VKNILAQKVEE---LPQREQNLDWQEKELAQELEE------LEWDMEELSW 1730
Query: 289 SQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRE 348
+ + ++ + E+KK E E L ++E + E L +E E+L Q +
Sbjct: 1731 KEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEK 1790
Query: 349 LEEQNLTLFQYSQD-VDENLEEVNKREKVIQDKTN-SNIEFLLEQEKML---KANCVREE 403
+ E+ L + + +++ ++ KRE+ I + + +L Q+K L K N +E+
Sbjct: 1791 MPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEK 1850
Query: 404 EKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVE 463
EK A Q K L E + +++ L+ + K+ K+ L +VE
Sbjct: 1851 EKLA--QRKENLLYNKERLTHSKKQLVQ-VKNKLGMFNKI---------------LAQVE 1892
Query: 464 SRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQP 523
+L + + + ++ E +++ Q E D K++++ QE++K ALEKA+ Q
Sbjct: 1893 EKLTQEKETVIKKKEKLAETEKKLVQVE------DSLAKKQEKLAQEKMKLALEKAMVQG 1946
Query: 524 KKKLGRRLVFHSKPPSGNKQQLPLVNE 550
KK+L L + + N + L E
Sbjct: 1947 KKRLRGELDIAKEEKALNLEMKRLAEE 1973
Score = 52.4 bits (124), Expect = 1e-06
Identities = 97/445 (21%), Positives = 182/445 (40%), Gaps = 37/445 (8%)
Query: 129 KRNTIKKFEKDIAMRERQLKKAEKKLQDDA--LAFEEFLRENDQRSVDALKMAAQETINK 186
K+ + + EK + E L K ++KL + LA E+ + + +R L +A +E
Sbjct: 1905 KKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALN 1964
Query: 187 LQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQAL-KRAQASK 245
L+M L + M + K ++K E + K Q++Q L +R + +
Sbjct: 1965 LEMK-RLAEEKMRLVEGKETLSKGETPETSRQR----------KMTQVEQELFERKLSLE 2013
Query: 246 SKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKK 305
K + +ILA S +G LE + + QG+ K SR L + E
Sbjct: 2014 EKILLHEDRILAMEE--SEIAKGKLEFTRGQRIFV----QGQRKLAKASRKLIKKRESLS 2067
Query: 306 SNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDE 365
A+ +L+ L DE + E K L R L + L D E
Sbjct: 2068 KEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSE 2127
Query: 366 NLEEVNKREKVIQDK----TNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEF 421
E+ K EK + K N + ++EKM + EE K A + L E
Sbjct: 2128 KRSELTKDEKKLARKQRKLANKMRRMINKEEKMTE-----EESKLARKHSEVILDDEEEG 2182
Query: 422 NSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNP-IQKLVKVESRLVELCDLIESIPKEN 480
+ +E+ I L ++ + + GD + + + ++ E E+ L++ + K+
Sbjct: 2183 GIEEEEV-IPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQE 2241
Query: 481 VEAIERMKQKEWRQKFRDEKMKEKQ---RHQQERLKAALEKAVAQPKKKLGRRL---VFH 534
+ E +++E ++ +E+++E++ + ++E + +EK + KKK + V
Sbjct: 2242 SLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQE 2301
Query: 535 SKPPSGNKQQLPLVNETKTKSQEEE 559
+ K+++ ET++ S EEE
Sbjct: 2302 KEEVFEEKEEIMSEEETESLSDEEE 2326
Score = 32.0 bits (71), Expect = 1.6
Identities = 32/132 (24%), Positives = 60/132 (45%), Gaps = 5/132 (3%)
Query: 401 REEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKIT---QVYKVCIGDAEDDGLNPIQ 457
+EE + LQ + KL GE S +E+L + K QV++ + + +
Sbjct: 1482 KEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDE 1541
Query: 458 KLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALE 517
+ V +E + + E E I+ ++ +W + R EK+R Q+ER A E
Sbjct: 1542 EEVTLEEEVSREGEEKEQQVTEEQRHIQ--EEHKWARIHRKRARAEKKRAQEERKLAQEE 1599
Query: 518 KAVAQPKKKLGR 529
+ +AQ +++L +
Sbjct: 1600 EKLAQEERQLAQ 1611
Score = 30.8 bits (68), Expect = 3.5
Identities = 45/193 (23%), Positives = 89/193 (46%), Gaps = 19/193 (9%)
Query: 340 EELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANC 399
EE+LQ E++ L ++ Q V EN+ +E+ +D+ +E + +E K
Sbjct: 1507 EEMLQ-----EDKKLKWEEWKQ-VWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQ 1560
Query: 400 VREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKL 459
V EE++ +Q + K + A++ K+ + K + E+ ++L
Sbjct: 1561 VTEEQR--HIQEEHKWARIHRKRARAEK-------KRAQEERK--LAQEEEKLAQEERQL 1609
Query: 460 VKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKM-KEKQRHQQERLKAALE- 517
+ E +L + I +E +A + QKE R EK+ +E ++ Q+R K A +
Sbjct: 1610 AQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKW 1669
Query: 518 KAVAQPKKKLGRR 530
+ VA+ ++KL ++
Sbjct: 1670 EKVAREEEKLAKK 1682
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 58.5 bits (140), Expect = 2e-08
Identities = 88/431 (20%), Positives = 194/431 (45%), Gaps = 37/431 (8%)
Query: 137 EKDIAMRERQLKKAEKKLQDDALAF---EEFLRENDQRSVDALKMAAQETINKLQMTAEL 193
E+ + +E+Q+++ E+K++D +E LRE ++R + KM QE K+Q +
Sbjct: 337 EERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQE--EKMQEEERI 394
Query: 194 KKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQA--SKSKANII 251
++ +++ + + + E + K + + K WQ Q+ ++ + + K
Sbjct: 395 REREKKMREEEETMREQE---EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
Query: 252 LPKILAKLSLHSSNKE--GILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLA 309
KI + +E G ++ R + E Q + + K R E+K +
Sbjct: 452 EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK-----MRDQEQKMWDQE 506
Query: 310 ESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEE 369
E +D E L + E + + ++ + EE ++ ++ +EQ + + + E E
Sbjct: 507 ERMWEQD--ERLREKEERMREQKKMW--QQEEKMREEKKTQEQEKKTWDQEEKMREE-ER 561
Query: 370 VNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEIL 429
+ +REK ++++ E + EQE+ ++ +EEK E + K++ E + +E +
Sbjct: 562 MREREKKMREEE----EMMREQEEKMQ----EQEEKMREQE--EKMWEQEEKMQEQEEKM 611
Query: 430 IDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQ 489
+ K Q + + + E+ +K+ + E ++ E + + ++ E E+M+
Sbjct: 612 WEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQG 671
Query: 490 KEWRQKFRDEKMK---EKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSGNKQQLP 546
+E + + ++EKM+ EK R Q+E+++ EK Q +K G+ + K++
Sbjct: 672 QEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEE-- 729
Query: 547 LVNETKTKSQE 557
+ + K K QE
Sbjct: 730 RIRDQKEKMQE 740
Score = 40.0 bits (92), Expect = 0.006
Identities = 55/249 (22%), Positives = 106/249 (42%), Gaps = 58/249 (23%)
Query: 329 DLEPALYFKEPEELLQVLRELEEQNLT-----------LFQYSQDVDENLEEVN----KR 373
+LE ALY+ + R+ E+ NL + ++ ++ L V+ K
Sbjct: 103 ELETALYYSQ-----DAARKFEDGNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKA 157
Query: 374 EKVIQDKTNSNIEFLLEQEKMLKANCVREEE---KAAELQLKSKLFSFGEFNSDAQEILI 430
++ I++ T LE L N + EE K AELQ K +L E ++ +
Sbjct: 158 DRYIEELTKERDALSLE----LYRNTITNEELKKKNAELQEKLRL---AESEKSEIQLNV 210
Query: 431 DSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQK 490
L +K+ + K + + + L +++ + E L +E + I + ++K
Sbjct: 211 KELKRKLERA-KFLLPQVQTNTLQ--EEMWRQEEEL-----------REQEKKIRKQEEK 256
Query: 491 EWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSGNKQQLPLVNE 550
WRQ+ R + + K R Q+E+++ EK + + +K+L +Q+ L +
Sbjct: 257 MWRQEERLREQEGKMREQEEKMRRQ-EKRLREQEKEL-------------REQEKELREQ 302
Query: 551 TKTKSQEEE 559
K + QEE+
Sbjct: 303 KKLREQEEQ 311
Score = 39.7 bits (91), Expect = 0.007
Identities = 97/456 (21%), Positives = 195/456 (42%), Gaps = 84/456 (18%)
Query: 116 QRDRFLL-EYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVD 174
+R +FLL + +T + + + E+++ +E++++K E+K+ EE LRE +
Sbjct: 218 ERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ----EERLREQEG---- 269
Query: 175 ALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSP---KH 231
KM QE ++++ ++ + E+ + E LRE K QM K
Sbjct: 270 --KMREQEE--------KMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKM 319
Query: 232 WQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQG 291
W+ ++ ++ + + +E + E+ + + E + RD +
Sbjct: 320 WEQEEKMREQEEKMWR-----------------QEERLWEQEKQ---MREQEQKMRDQEE 359
Query: 292 KPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEE 351
+ R EK++ + E + E + ++E + E + +E EE +RE EE
Sbjct: 360 RMWEQDERLREKEE-RMREQEKMWEQEEKMQEEERIREREKKM--REEEE---TMREQEE 413
Query: 352 QNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQL 411
+ Q +EN+ E ++E Q + E L EQEKM + +EEK E +
Sbjct: 414 K-------MQKQEENMWEQEEKEWQ-QQRLPEQKEKLWEQEKMQE-----QEEKIWEQEE 460
Query: 412 KSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCD 471
K + D +E+ KK+ + K+ + ED +K+ E ++ + +
Sbjct: 461 KIR---------DQEEMW--GQEKKMWRQEKM--REQEDQMWEQEEKMRDQEQKMWDQEE 507
Query: 472 LIESIPKENVEAIERMKQ--KEWRQ--KFRDEKMKEKQRH----QQERLKAALEKAVAQP 523
+ + E ERM++ K W+Q K R+EK ++Q Q+E+++ E+ + +
Sbjct: 508 RMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE--EERMRER 565
Query: 524 KKKLGRRLVFHSKPPSGNKQQLPLVNETKTKSQEEE 559
+KK+ + ++Q + E + K E+E
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE 601
Score = 37.4 bits (85), Expect = 0.037
Identities = 77/429 (17%), Positives = 173/429 (40%), Gaps = 34/429 (7%)
Query: 98 RLIEGSDTKRTVHEFINDQRDRFL-----LEYALSTKRNTIKKFEKDIAMRERQ-LKKAE 151
RL E R + + DQ +R L R K +E++ M+E + +++ E
Sbjct: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRERE 398
Query: 152 KKLQDDALAFEEFLRENDQR-SVDALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKT 210
KK++++ EE +RE +++ M QE Q +K + Q E +
Sbjct: 399 KKMREE----EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454
Query: 211 EFLLREYMKYGFFLLQMSPKHWQIQQALKRAQA---SKSKANIILPKILAKLSLHSSNKE 267
+ E ++ + K W+ ++ ++ + K K+ + E
Sbjct: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514
Query: 268 GILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMD 327
+ E+ R + E + + T+ EKK + E E+ + + E
Sbjct: 515 RLREKEER---MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR---EREKK 568
Query: 328 VDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVI-----QDKTN 382
+ E + ++ E++ + ++ EQ +++ + + E E++ ++E+ + +DK
Sbjct: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
Query: 383 SNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYK 442
E + EQE+ ++ + E+ +++ + + E QE + +K+ Q +
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKM-QGQE 687
Query: 443 VCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMK 502
+ + E+ +K+ E ++ +E + E M++KE R + + EKM+
Sbjct: 688 EKMREQEEKMRGQEEKMWGQEEKMWG--------QEEKMWGQEEMREKEERIRDQKEKMQ 739
Query: 503 EKQRHQQER 511
E+ +ER
Sbjct: 740 ERLPEHEER 748
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 56.6 bits (135), Expect = 6e-08
Identities = 97/433 (22%), Positives = 180/433 (41%), Gaps = 71/433 (16%)
Query: 119 RFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFE---EFLRENDQRSVDA 175
R LLE L K+ + E+ + +RER+L + L+++ + + E +R+ QR +
Sbjct: 473 RELLEEVLEGKQ----RVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQ 528
Query: 176 LKMAAQE-TINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQI 234
L+ + Q+ T + + AE +K S V+ ++ E+ +T HWQ
Sbjct: 529 LRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETS---------------EETGHWQS 573
Query: 235 QQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESG-RTAVLSEDASQGRDSQGKP 293
+ +K ++ ++ KE + EE G + VL + Q R S G
Sbjct: 574 MFQKNKEDLRATKQELLQLRM---------EKEEMEEELGEKIEVLQRELEQARASAGD- 623
Query: 294 SRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLR------ 347
TR E K L + ++ L+ L + ++ +E E+ L VLR
Sbjct: 624 ----TRQVEVLKKELLRT---QEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRG 676
Query: 348 -ELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEK- 405
ELEEQNL L + Q + ++ EE +K + V + + +L Q + +RE ++
Sbjct: 677 RELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEAT-----VLGQRRAAVETTLRETQEE 731
Query: 406 ---------AAELQLKSK--LFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLN 454
E QLK L GE + L + Q+ + E++G
Sbjct: 732 NDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSL 791
Query: 455 PIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKA 514
K +E+RL E + + +E + + R ++E +Q+ ++ + + + E K
Sbjct: 792 AAAKRA-LEARLEEAQRGLARLGQEQ-QTLNRALEEEGKQR----EVLRRGKAELEEQKR 845
Query: 515 ALEKAVAQPKKKL 527
L++ V + K+L
Sbjct: 846 LLDRTVDRLNKEL 858
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 55.5 bits (132), Expect = 1e-07
Identities = 81/403 (20%), Positives = 177/403 (43%), Gaps = 33/403 (8%)
Query: 135 KFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAELK 194
+ E+ ++ Q KKA++ + EE +E D S++ + + K + A+L+
Sbjct: 164 ELEQALSAVATQKKKADRYI-------EELTKERDALSLELYRNTITDEELK-EKNAKLQ 215
Query: 195 KASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQA--SKSKANIIL 252
+ V++ KSEI L+ ++ LL + K Q+ +K +A +
Sbjct: 216 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 275
Query: 253 PKILAKLSLHSSNKEGILEES--GRTAVLSEDASQGRDSQGKPSRS--LTRTPEKKKSNL 308
++ +L+ K EE R + E + R+ + K R + E+K
Sbjct: 276 NELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 335
Query: 309 AESFGSEDSLEFLLDDEMDVD--LEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDEN 366
E ++ L+++M + ++ EE ++ + +EQ +++ + + E
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 395
Query: 367 LEEVNKREKVIQD---KTNSNIEFLLEQEKMLKAN---CVREEEKAAELQLKSKLFSFGE 420
E++ ++E+++Q+ K E + EQE+ ++ R+EEK E + K+ E
Sbjct: 396 EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQE--KKIREQEE 453
Query: 421 FNSDAQEILIDSLSKKITQVYKVCIGDA-----EDDGLNPIQKLVKVESRLVELCDLIES 475
+ +E++ + K Q K+C +A E+ +K+ + E ++ E + I
Sbjct: 454 KIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKI-- 511
Query: 476 IPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEK 518
+E E ++ ++K W Q+ + + +EK + Q+E+++ EK
Sbjct: 512 --REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 552
Score = 49.7 bits (117), Expect = 7e-06
Identities = 79/408 (19%), Positives = 168/408 (41%), Gaps = 40/408 (9%)
Query: 118 DRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALK 177
DR++ E +++ + I + +LK+ KLQ+ L E + Q +V LK
Sbjct: 180 DRYIEELTKERDALSLELYRNTIT--DEELKEKNAKLQEK-LQLVESEKSEIQLNVKELK 236
Query: 178 MAAQET---INKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQ- 233
+ + + Q+ AE E+Q+V AK + + E + Q K W+
Sbjct: 237 RKLERAKLLLPQQQLQAEADHLGKELQSVS---AKLQAQVEENELWNRLNQQQEEKMWRQ 293
Query: 234 ----------IQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDA 283
IQ+ ++ + + K + K +E + E+ + L E
Sbjct: 294 EEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 353
Query: 284 SQGR----DSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEP 339
+ + + R EK++ A+ + E+ + E +E
Sbjct: 354 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR-----------EQEEKIREQ 402
Query: 340 EELLQVLRE-LEEQNLTLFQYSQDVDENLEEVNKREKVIQD---KTNSNIEFLLEQEKML 395
EE++Q E + EQ +++ +++ E E++ ++E+ I++ K E + EQE+M+
Sbjct: 403 EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 462
Query: 396 KANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNP 455
+ + E+ ++ + E QE I KKI + + I + E+
Sbjct: 463 QEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEK-IREQEEMMQEQ 521
Query: 456 IQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKE 503
+K+ + E ++ E + ++ ++ E+M+++E R + ++EKM+E
Sbjct: 522 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 44.7 bits (104), Expect = 2e-04
Identities = 80/400 (20%), Positives = 174/400 (43%), Gaps = 58/400 (14%)
Query: 170 QRSVDALKMAAQETINKL----QMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLL 225
Q +V L+ A++ I++L + EL++A + AV ++ K + + E K L
Sbjct: 138 QHAVKQLEGEARDLISRLHDSWKFAGELEQA---LSAVATQKKKADRYIEELTKERDALS 194
Query: 226 QMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQ 285
++ + LK A K+ KL L S K SE
Sbjct: 195 LELYRNTITDEELKEKNA----------KLQEKLQLVESEK-------------SEIQLN 231
Query: 286 GRDSQGKPSRSLTRTPEKKKSNLAESFGSE-DSLEFLLDDEMDV-DLEPALYFKEPEELL 343
++ + K R+ P+++ A+ G E S+ L +++ +L L ++ E++
Sbjct: 232 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 291
Query: 344 QVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKML--KANCVR 401
+ +++E+ + + + + E E++ ++E+++ +K E + QE+M+ K +R
Sbjct: 292 RQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKE----EKMRRQEEMMWEKEEKIR 347
Query: 402 EEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVK 461
E E+ Q K + + +E I K+ Q K+ + +K+ +
Sbjct: 348 ELEEKMHEQEKIR----EQEEKRQEEEKIREQEKRQEQEAKMWRQE---------EKIRE 394
Query: 462 VESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVA 521
E ++ E E + +E E + ++K W Q+ ++ +EK R Q+E+++ EK +
Sbjct: 395 QEEKIREQ----EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ-EKKIR 449
Query: 522 QPKKKLGRR--LVFHSKPPSGNKQQLPLVNETKTKSQEEE 559
+ ++K+ + ++ + G ++ E K + QEE+
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK 489
Score = 42.0 bits (97), Expect = 0.002
Identities = 79/433 (18%), Positives = 173/433 (39%), Gaps = 52/433 (12%)
Query: 132 TIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTA 191
T +K E +A+ Q A K+L+ +A R+ R D+ K A + +
Sbjct: 124 TCQKTELQMALYYSQ--HAVKQLEGEA-------RDLISRLHDSWKFAGELEQALSAVAT 174
Query: 192 ELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANII 251
+ KKA ++ + E + L E + ++ K+ ++Q+ L+ ++ KS+ +
Sbjct: 175 QKKKADRYIEELTKE---RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLN 231
Query: 252 LPKIL-----AKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKS 306
+ ++ AKL L + + G+ Q + + + L + E+K
Sbjct: 232 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 291
Query: 307 NLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDEN 366
E + E + + E + + ++ E + + ++ Q +++ + + E
Sbjct: 292 RQEEKIQERE--EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 349
Query: 367 LEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQ 426
E+++++EK+ + ++EK + +RE+EK E + K Q
Sbjct: 350 EEKMHEQEKIRE-----------QEEKRQEEEKIREQEKRQEQEAKMW----------RQ 388
Query: 427 EILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIER 486
E I +KI + ++ E K+ + E ++ E E +E E + R
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEE--------KMGEQEEKMWEQ----EEEMQEQEEKMRR 436
Query: 487 MKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSGNKQQLP 546
++K Q+ + + +EK R Q+E ++ EK Q K + + +Q+
Sbjct: 437 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEK 496
Query: 547 LVNETKTKSQEEE 559
+ + K ++EE
Sbjct: 497 IREQEKKIREQEE 509
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 53.1 bits (126), Expect = 7e-07
Identities = 116/565 (20%), Positives = 219/565 (38%), Gaps = 78/565 (13%)
Query: 27 KIFFRDLFLVKENEMAAKETEKFMNRNMKVYQKTTFSSRMKSHSYLSQLAFYPKRSGRSF 86
K+FF+ L EM ++ + + R V + + + F + + R+F
Sbjct: 765 KVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAF 824
Query: 87 EKFGPGP-----APIPRLIEGSDTKR---TVHEFINDQRDRFLLEYA----LSTKRNTIK 134
P I L++ ++T++ T+ E +D A L K T+
Sbjct: 825 MNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLL 884
Query: 135 KFEKDIAMRERQ----LKKAEKKLQD---DALAFEEFLRENDQRSVDALKMAAQETINKL 187
K + D+ ++ + L AE++ + + + E ++E +R+ + ++ A+ T K
Sbjct: 885 KEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKR 944
Query: 188 QMTAELKKASMEVQAVKSEIAKTEF-----------LLREYMKYGFFLLQMSPKHWQIQ- 235
++ E + ++ ++ +AK E L E + ++S + +Q
Sbjct: 945 KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQE 1004
Query: 236 ---QALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGK 292
Q L QA + K NI L K KL + EG LE+ + + E A + + K
Sbjct: 1005 THQQTLDDLQAEEDKVNI-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLK 1063
Query: 293 PSRSLTRTPEKKK--------------SNLAESFGSEDSLEFLLDDEM------------ 326
++ T E K SNL E ++E L ++
Sbjct: 1064 LAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGE 1123
Query: 327 DVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIE 386
+++ E A K ++ + RELEE + L + +E KRE Q E
Sbjct: 1124 EIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEE 1183
Query: 387 FLLEQEKMLKANCVREEEKAAEL--------QLKSKL---FSFGEFNSDAQEILIDSLSK 435
L+ E M+ A + + AEL ++K KL S + +D +++SK
Sbjct: 1184 ATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISK 1243
Query: 436 KITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQK 495
+ K+C + +D ++ ++ + + RL+ DL + EA E +Q + +
Sbjct: 1244 AKGNLEKMC--RSLEDQVSELKTKEEEQQRLIN--DLTAQRARLQTEAGEYSRQLDEKDA 1299
Query: 496 FRDEKMKEKQRHQQ--ERLKAALEK 518
+ + KQ Q E LK LE+
Sbjct: 1300 LVSQLSRSKQASTQQIEELKHQLEE 1324
Score = 47.4 bits (111), Expect = 4e-05
Identities = 84/422 (19%), Positives = 172/422 (40%), Gaps = 43/422 (10%)
Query: 125 ALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETI 184
+LST+ +K ++ + L++ K LQ + E + E ++ + K+ Q
Sbjct: 1479 SLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQ 1538
Query: 185 NKLQMTAELKKASMEVQAVKSEIAKTEFLL--------REYMKYGFFLLQMSPKHWQIQQ 236
K ++ A L++A ++ + +I + + L R+ + + Q+ H ++ +
Sbjct: 1539 EKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVE 1598
Query: 237 ALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRS 296
++ ++ ++ ++ K+ + E L + R A +E R++QG +
Sbjct: 1599 TMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLA--AESLRNYRNTQGILKET 1656
Query: 297 LTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTL 356
+ + G ED E L E +L A E EEL L + E
Sbjct: 1657 QLHLDDALR-------GQEDLKEQLAIVERRANLLQA----EIEELWATLEQTERSRKIA 1705
Query: 357 FQYSQDVDE--------NLEEVNKREKVIQD--KTNSNIEFLLEQEKMLKANCVREEEKA 406
Q D E N +N ++K+ D + S +E ++++ + EEKA
Sbjct: 1706 EQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESR-------NAEEKA 1758
Query: 407 AELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVC---IGDAEDDGLNPIQKLV-KV 462
+ + + + ++ + K + Q K + +AE L +K + K+
Sbjct: 1759 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1818
Query: 463 ESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQ 522
E+R+ EL +E+ K N EA++ +++ E R K E+ R RL+ ++K A+
Sbjct: 1819 EARVRELEGEVENEQKRNAEAVKGLRKHERRVK-ELTYQTEEDRKNVLRLQDLVDKLQAK 1877
Query: 523 PK 524
K
Sbjct: 1878 VK 1879
Score = 46.6 bits (109), Expect = 6e-05
Identities = 82/442 (18%), Positives = 180/442 (40%), Gaps = 40/442 (9%)
Query: 126 LSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAA---QE 182
+ +R + K EK + R+L++ ++L++ A + N +R + K+ +
Sbjct: 1125 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEA 1184
Query: 183 TINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQ-QALKRA 241
T+ M A L+K + A E +++ ++ L+M +A+ +A
Sbjct: 1185 TLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKA 1244
Query: 242 QASKSKANIILPKILAKLSLHSSNKEGILEE--SGRTAVLSEDASQGRDSQGKPS----- 294
+ + K L +++L ++ ++ + + R + +E R K +
Sbjct: 1245 KGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQL 1304
Query: 295 ----RSLTRTPEKKKSNLAESFGSEDSLEFLLDDEM-DVDLEPALYFKEPEELLQVLREL 349
++ T+ E+ K L E ++++L L D DL Y +E E ++ R L
Sbjct: 1305 SRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRAL 1364
Query: 350 EEQNLTLFQ----YSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEK 405
+ N + Q Y D + EE+ + +K K ++ E + + A C E+
Sbjct: 1365 SKANSEVAQWRTKYETDAIQRTEELEEAKK----KLAQRLQEAEEHVEAVNAKCASLEKT 1420
Query: 406 AAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVY----------KVCIGDAEDDGLNP 455
LQ + + S+A +D + +V + + ++ + +
Sbjct: 1421 KQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSL 1480
Query: 456 IQKLVKVESRLVELCDLIESIPKEN------VEAIERMKQKEWRQKFRDEKMKEKQRHQQ 509
+L KV++ E D +E++ +EN + + + +Q EK+K++ ++
Sbjct: 1481 STELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEK 1540
Query: 510 ERLKAALEKAVAQPKKKLGRRL 531
++AALE+A A + + G+ L
Sbjct: 1541 CEIQAALEEAEASLEHEEGKIL 1562
Score = 33.5 bits (75), Expect = 0.53
Identities = 52/280 (18%), Positives = 115/280 (41%), Gaps = 27/280 (9%)
Query: 111 EFINDQRDRFLLEYALSTKRNTIK----KFEKDIAMRERQLKKAEKKLQDDALAFEEFLR 166
++ +Q + L+ ALS + + K+E D R +L++A+KKL EE +
Sbjct: 1349 QYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHV- 1407
Query: 167 ENDQRSVDALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQ 226
+V+A + ++T +LQ E++ ++V+ + A + R + K L +
Sbjct: 1408 ----EAVNAKCASLEKTKQRLQ--NEVEDLMLDVERSNAACAALDKKQRNFDK---VLSE 1458
Query: 227 MSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQG 286
K+ + Q L+ +Q + L K+ E + E+ L ++ S
Sbjct: 1459 WKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKN---LQQEISDL 1515
Query: 287 RDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVL 346
+ + + + + KK E + +LE E + LE E ++L++
Sbjct: 1516 TEQIAEGGKQIHELEKIKKQVEQEKCEIQAALE-----EAEASLE-----HEEGKILRIQ 1565
Query: 347 RELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIE 386
EL + + + + DE ++++ + + + S ++
Sbjct: 1566 LELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLD 1605
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 52.8 bits (125), Expect = 8e-07
Identities = 83/388 (21%), Positives = 165/388 (42%), Gaps = 48/388 (12%)
Query: 177 KMAAQETINKLQMTAELK-KASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQ 235
KM +E KL +T E K KA+ E ++ E + + L+ + + Q + W+ +
Sbjct: 349 KMQEEEPQKKLPVTFEDKRKANYERGNMELE-KRRQALMEQQQREAERKAQKEKEEWERK 407
Query: 236 QALKRAQASKSKANIILPKILAKL-SLHSSNKEGILEESGRTAVLSEDASQGR------- 287
Q + Q + K + L K L K L +E ++ R ++ + R
Sbjct: 408 Q--RELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 465
Query: 288 ------DSQGKPSRSLTRTPEKKKS---NLAESFGSEDSLEFLLDD----------EMDV 328
+ + + + R KKK+ L G + L D E++V
Sbjct: 466 RRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEV 525
Query: 329 -DLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEF 387
D + L E ++L Q L+E + + + L Q ++E ++ + + +S +
Sbjct: 526 LDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQ-----FSNTPDSGVSL 580
Query: 388 L----LEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEI--LIDSLSKKITQVY 441
L LE+E++ + ++E+ A E + SKL FN+ +E+ ++ + Q+Y
Sbjct: 581 LHKKSLEKEELCQR--LKEQLDALEKETASKLSEMDSFNNQLKELRETYNTQQLALEQLY 638
Query: 442 KVC---IGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRD 498
K+ + + E L +QK + + E++ KEN+ E KQK +++
Sbjct: 639 KIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQ 698
Query: 499 EKMKEKQRHQQERLKAALEKAVAQPKKK 526
EK++E++R +E+ + + A+ KK+
Sbjct: 699 EKIQEEERKAEEKQRKDKDTLKAEEKKR 726
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 52.4 bits (124), Expect = 1e-06
Identities = 88/459 (19%), Positives = 191/459 (41%), Gaps = 39/459 (8%)
Query: 118 DRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALK 177
DR++ E +++ + I + +LK+ KLQ+ L E + Q +V LK
Sbjct: 253 DRYIEELTKERDALSLELYRNTIT--DEELKEKNAKLQEK-LQLVESEKSEIQLNVKELK 309
Query: 178 MAAQET---INKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQ- 233
+ + + Q+ AE E+Q+V AK + + E + Q K W+
Sbjct: 310 RKLERAKLLLPQQQLQAEADHLGKELQSVS---AKLQAQVEENELWNRLNQQQEEKMWRQ 366
Query: 234 ---IQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQ 290
IQ+ ++ Q + K KI + +E + E+ + E+ ++ +
Sbjct: 367 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR-RQEEMMWEKEEK 425
Query: 291 GKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELE 350
+ + E+K L E ++ + + ++ EE ++ + +
Sbjct: 426 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK------------RQEEEKIREQEKRQ 473
Query: 351 EQNLTLFQYSQDVDENLEEVNKREKVI---QDKTNSNIEFLLEQEKMLKANCVREEEKAA 407
EQ +++ + + E E++ ++E+ + ++K + + E+++ + R+EEK
Sbjct: 474 EQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR 533
Query: 408 ELQ----LKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVE 463
E + K K+ E +E + K Q K I + E+ +K+ + E
Sbjct: 534 EQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEK--IREQEEKVWRQEEKIREQE 591
Query: 464 SRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKE---KQRHQQERLKAALEKAV 520
++ E + I + E E+M ++E + ++EKM+E K R Q+E+++ EK +
Sbjct: 592 EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQ-EKKI 650
Query: 521 AQPKKKLGRRLVFHSKPPSGNKQQLPLVNETKTKSQEEE 559
+ ++K+ + + +Q + E + K QE+E
Sbjct: 651 REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 689
Score = 51.6 bits (122), Expect = 2e-06
Identities = 83/441 (18%), Positives = 183/441 (41%), Gaps = 58/441 (13%)
Query: 135 KFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAELK 194
+ E+ ++ Q KKA++ + EE +E D S++ + TI ++ +
Sbjct: 237 ELEQALSAVATQKKKADRYI-------EELTKERDALSLELYR----NTITDEELKEKNA 285
Query: 195 KASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPK 254
K ++Q V+SE ++ + ++E L+ + ++ ++ QA L
Sbjct: 286 KLQEKLQLVESEKSEIQLNVKE--------LKRKLERAKLLLPQQQLQAEADHLGKELQS 337
Query: 255 ILAKLSLHSSNKE---GILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAES 311
+ AKL E + ++ E+ Q + + + R E+K E
Sbjct: 338 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 397
Query: 312 FGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVN 371
++ + + +++M ++ E + + ++ Q +++ + + E E+++
Sbjct: 398 MRRQEEMMWEKEEKMR---------RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 448
Query: 372 KREKVI-QDKTNSNIEFLLEQEKMLK--ANCVREEEKAAELQLKSKLFSFGEFNSDAQEI 428
++EK+ Q++ E + EQEK + A R+EEK E + K + QE
Sbjct: 449 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR----------EQEE 498
Query: 429 LIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPK--ENVEAIER 486
+ +KI + K+ E++ +++ + E ++ E ++ K E E I +
Sbjct: 499 KMWRQEEKIHEQEKI----REEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK 554
Query: 487 MKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKK--------KLGRRLVFHSKPP 538
++K WRQ+ + +EK R Q+E++ EK Q +K + + +
Sbjct: 555 QEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEK 614
Query: 539 SGNKQQLPLVNETKTKSQEEE 559
G +++ E K + QEE+
Sbjct: 615 MGEQEEKMCEQEEKMQEQEEK 635
Score = 50.1 bits (118), Expect = 6e-06
Identities = 70/387 (18%), Positives = 168/387 (43%), Gaps = 35/387 (9%)
Query: 133 IKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAE 192
I+++E+ I +E ++++ E+K+++ E+ R+ + KM QE + + +
Sbjct: 370 IQEWEEKIQEQEEKIREQEEKIREQE---EKMRRQEEMMWEKEEKMRRQEEM-MWEKEEK 425
Query: 193 LKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIIL 252
+++ + + +I + E + E K + + K + ++ ++ + + +A
Sbjct: 426 MRRQEEMMWEKEEKIRELEEKMHEQEK----IREQEEKRQEEEKIREQEKRQEQEA---- 477
Query: 253 PKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESF 312
K+ + +E I E+ + E + + + R +++ + E
Sbjct: 478 -KMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 536
Query: 313 GSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNK 372
E + + E + + +++ E++ ++ EQ +++ + + E E++ +
Sbjct: 537 EIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIRE 596
Query: 373 REKVIQDK---TNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEIL 429
+E+ I+++ T E + EQE+ + +EEK E + K + QE
Sbjct: 597 QEEKIREQEEMTQEQEEKMGEQEEKM----CEQEEKMQEQEEKMR----------RQEEK 642
Query: 430 IDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQ 489
I KKI + + I + E+ +K+ + E ++ E E +E E + R ++
Sbjct: 643 IREQEKKIREQEEK-IREQEEMMQEQEEKMWEQEEKMCEQ----EEKMQEQEEKMRRQEE 697
Query: 490 KEWRQKFRDEKMKEKQRHQQERLKAAL 516
K W Q+ R + +EK + QE L+AA+
Sbjct: 698 KMWEQEVRLRQQEEKMQEHQEHLEAAI 724
Score = 45.4 bits (106), Expect = 1e-04
Identities = 70/383 (18%), Positives = 168/383 (43%), Gaps = 26/383 (6%)
Query: 145 RQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAA--QETINKLQMTAE-LKKASMEVQ 201
++L+ KLQ E + R N Q+ + QE K+Q E +++ +++
Sbjct: 333 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 392
Query: 202 AVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPKILAKLSL 261
+ ++ + E ++ E + + + W+ ++ ++R + + + ++ K+
Sbjct: 393 EQEEKMRRQEEMMWEKEEK---MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 449
Query: 262 HSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFL 321
+E + + ++ Q ++++ R E+K E ++ E +
Sbjct: 450 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQE--EKI 507
Query: 322 LDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVI---Q 378
+ E + E +E EE+ + ++ EQ +++ + + E E++ K+E+ + +
Sbjct: 508 HEQEKIREEEKR---QEQEEMWRQEEKIREQE-EIWRQKEKIHEQEEKIRKQEEKMWRQE 563
Query: 379 DKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKIT 438
+K + E + EQE+ + R+EEK E + K+ E + +E+ + K
Sbjct: 564 EKMHDQEEKIREQEEKVW----RQEEKIREQE--EKIREQEEKIREQEEMTQEQEEKMGE 617
Query: 439 QVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLI---ESIPKENVEAIERMKQKEWRQK 495
Q K+C + E+ +K+ + E ++ E I E +E E ++ ++K W Q+
Sbjct: 618 QEEKMC--EQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 675
Query: 496 FRDEKMKEKQRHQQERLKAALEK 518
+ + +EK + Q+E+++ EK
Sbjct: 676 EKMCEQEEKMQEQEEKMRRQEEK 698
Score = 41.2 bits (95), Expect = 0.003
Identities = 54/244 (22%), Positives = 117/244 (47%), Gaps = 28/244 (11%)
Query: 329 DLEPALYFKEP--EELLQVLRELEEQNLTLFQYSQDVDENLEEV----NKREKVIQDKTN 382
+L+ ALY+ + ++L R+L + ++++ ++++ L V K ++ I++ T
Sbjct: 202 ELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTK 261
Query: 383 SNIEFLLEQEKMLKANCVREEE---KAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQ 439
LE L N + +EE K A+LQ K +L E ++ + L +K+ +
Sbjct: 262 ERDALSLE----LYRNTITDEELKEKNAKLQEKLQLV---ESEKSEIQLNVKELKRKLER 314
Query: 440 VYKVCIGD----AEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQK 495
K+ + AE D L ++L V ++L + E + N ++ ++K WRQ+
Sbjct: 315 A-KLLLPQQQLQAEADHLG--KELQSVSAKLQAQVEENELWNRLN----QQQEEKMWRQE 367
Query: 496 FRDEKMKEKQRHQQERLKAALEKAVAQPKK-KLGRRLVFHSKPPSGNKQQLPLVNETKTK 554
+ ++ +EK + Q+E+++ EK Q +K + +++ + ++++ E K +
Sbjct: 368 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 427
Query: 555 SQEE 558
QEE
Sbjct: 428 RQEE 431
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 52.4 bits (124), Expect = 1e-06
Identities = 92/467 (19%), Positives = 196/467 (41%), Gaps = 50/467 (10%)
Query: 125 ALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETI 184
+LST+ +K ++ K+ K LQ++ E L E + + K+ Q +
Sbjct: 1478 SLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEV 1537
Query: 185 NKLQMTAELKKASMEVQAVKSEI--AKTEF------LLREYMKYGFFLLQMSPKHWQIQQ 236
KL++ + L++A ++ + +I A+ EF + R+ + + Q H ++
Sbjct: 1538 EKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVD 1597
Query: 237 ALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRS 296
+L+ + +++++ + ++ K+ + E L + R A ++ + S K ++
Sbjct: 1598 SLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQI 1657
Query: 297 LTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTL 356
+ +L E+ + LL E++ + E + R+L EQ L
Sbjct: 1658 QLDDAVRANDDLKENIAIVERRNNLLQAELE-------ELRAVVEQTERSRKLAEQE--L 1708
Query: 357 FQYSQDV----DENLEEVNKREKVIQDKT--NSNIEFLLEQEKMLKANCVREEEKAAELQ 410
+ S+ V +N +N+++K+ D T S +E +++ C EEKA +
Sbjct: 1709 IETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQE-------CRNAEEKAKKAI 1761
Query: 411 LKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVC---IGDAEDDGLNPIQK-LVKVESRL 466
+ + + ++ + K + Q K + +AE L +K L K+E+R+
Sbjct: 1762 TDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARV 1821
Query: 467 VELCDLIESIPKENVEAIERMKQKEWRQK-------------FRDEKMKEKQRHQQERLK 513
EL +E+ K N E+++ M++ E R K R + + +K + + + K
Sbjct: 1822 RELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYK 1881
Query: 514 AALEKAVAQPKKKLGR-RLVFHSKPPSGNKQQL--PLVNETKTKSQE 557
E+A Q L + R V H + + + VN+ + KS++
Sbjct: 1882 RQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRD 1928
Score = 44.7 bits (104), Expect = 2e-04
Identities = 102/463 (22%), Positives = 187/463 (40%), Gaps = 74/463 (15%)
Query: 122 LEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKM--- 178
LE L +R K EK + R+L++ ++L++ A + N +R + KM
Sbjct: 1120 LEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD 1179
Query: 179 -----------AAQETINKLQMTAELKKASMEVQAVKSEIAK--TEFLLREYMKYGFFLL 225
AA AEL + +Q VK ++ K +EF L E +
Sbjct: 1180 LEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKL-ELDDVTSNME 1238
Query: 226 QMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQ 285
Q+ +++ + + ++ + L + L+ ++ + + E+G A E+
Sbjct: 1239 QIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEA 1298
Query: 286 GRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEM-DVDLEPALYFKEPE---E 341
+ S T+ E K L E ++++L L D DL Y +E E E
Sbjct: 1299 LISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAE 1358
Query: 342 LLQVL----------------------RELEEQNLTLFQYSQDVDENLEEVNKREKVIQD 379
L +VL ELEE L Q QD +E +E VN + + +
Sbjct: 1359 LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSL-E 1417
Query: 380 KTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFS--FGEFNSDAQEIL--IDSLSK 435
KT ++ +E L + R AA L K + F E+ +E ++S K
Sbjct: 1418 KTKHRLQNEIED---LMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 1474
Query: 436 KI----TQVYKVCIGDAEDDGLNPIQKLVKVESRL-VELCDLIESIPK--ENVEAIERMK 488
+ T+++K + +A ++ L ++ + L E+ DL E + + +NV +E++
Sbjct: 1475 EARSLSTELFK--LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKV- 1531
Query: 489 QKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRL 531
R++ EK++ L++ALE+A A + + G+ L
Sbjct: 1532 ----RKQLEVEKLE---------LQSALEEAEASLEHEEGKIL 1561
Score = 42.4 bits (98), Expect = 0.001
Identities = 85/429 (19%), Positives = 175/429 (40%), Gaps = 65/429 (15%)
Query: 126 LSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETI- 184
L + + + K E+Q+ E L+ + + E +R ++ QE+I
Sbjct: 1012 LQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDL--ERAKRKLEGDLKLTQESIM 1069
Query: 185 ----NKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKR 240
+KLQ+ +LKK ++ S+I + L + K L + + ++++ L+
Sbjct: 1070 DLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKK---LKENQARIEELEEELEA 1126
Query: 241 AQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQ-GKPSRSLTR 299
+ +++K + K+ + LS LEE+G + + ++ R+++ K R L
Sbjct: 1127 ERTARAK----VEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEE 1182
Query: 300 TPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQY 359
+ ++ A L +++D L +V ++LE++
Sbjct: 1183 ATLQHEATAAALRKKHADSVAELGEQID-------------NLQRVKQKLEKEKSEFKLE 1229
Query: 360 SQDVDENLEEV-------NKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLK 412
DV N+E++ K + ++D+ N L E ++ L + A+LQ +
Sbjct: 1230 LDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQR----AKLQTE 1285
Query: 413 SKLFSFGEF--NSDAQEILIDSLSK---KITQVYKVCIGDAEDDGLNPIQKLVKVESRLV 467
+ GE + +E LI L++ TQ + E++G ++S
Sbjct: 1286 N-----GELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARH 1340
Query: 468 ELCDLIESIPKENVEA---IERMKQK------EWRQKF------RDEKMKEKQRHQQERL 512
+ CDL+ +E EA ++R+ K +WR K+ R E+++E ++ +RL
Sbjct: 1341 D-CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1399
Query: 513 KAALEKAVA 521
+ A E A
Sbjct: 1400 QDAEEAVEA 1408
Score = 31.2 bits (69), Expect = 2.6
Identities = 43/207 (20%), Positives = 87/207 (42%), Gaps = 27/207 (13%)
Query: 334 LYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREK--------VIQDKTNSNI 385
LYFK L E E++ T+ + + E LE+ R K ++Q+K + +
Sbjct: 834 LYFKIKPLLKSA--ETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQL 891
Query: 386 EFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEI----------LIDSLS- 434
+ EQ+ + A ++ ++QL++K+ E D +E+ L D S
Sbjct: 892 QVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSE 951
Query: 435 -KKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWR 493
KK ++ + E + K+ + + L ++I + KE ++ Q+ +
Sbjct: 952 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKE-----KKALQEAHQ 1006
Query: 494 QKFRDEKMKEKQRHQQERLKAALEKAV 520
Q D +++E + + + K LE+ V
Sbjct: 1007 QALDDLQVEEDKVNSLSKSKVKLEQQV 1033
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 52.4 bits (124), Expect = 1e-06
Identities = 92/432 (21%), Positives = 191/432 (44%), Gaps = 41/432 (9%)
Query: 126 LSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALK---MAAQE 182
L+++ NT ++ + MR + L++ +KLQ + E + + QR ++ LK A+E
Sbjct: 806 LASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQL-QRQIEDLKGDEAKAKE 864
Query: 183 TINKLQ------------MTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPK 230
T+ K + E K+A +A+++E+ + L + + L + +
Sbjct: 865 TLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKE 924
Query: 231 HWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQ 290
+ ++ L+R + L K + KL ++ + E+ RT+ L E +Q + +
Sbjct: 925 ESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMAD----IVEASRTSTL-ELQNQLDEYK 979
Query: 291 GKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELE 350
K R L + K E+ S + + DEM + E ++ ++ R+L
Sbjct: 980 EKNRRELAEMQRQLKEKTLEAEKSRLTA-MKMQDEMRLMEEELRDYQRAQDEALTKRQLL 1038
Query: 351 EQNLTLFQYSQDVDENLEEVNKR-EKVIQDKTNSNIEFLLEQEK----MLKANCVREEEK 405
EQ L +Y + +L++ R K ++DK S +E LE+E+ +L R E+
Sbjct: 1039 EQTLKDLEYELEAKSHLKDDRSRLVKQMEDKV-SQLEMELEEERNNSDLLSERISRSREQ 1097
Query: 406 AAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGD--AEDDGLNPIQKLVKVE 463
+L+ + + + +I ++ +K + G + +GL +V++E
Sbjct: 1098 MEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGL-----VVQME 1152
Query: 464 SRLVELCDLIESIPKE--NVEAIER---MKQKEWRQKFRDEKMKEKQRHQQERLK-AALE 517
+R+ EL D +ES ++ N++ R K KE + DE + + Q L+ A++
Sbjct: 1153 ARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMK 1212
Query: 518 KAVAQPKKKLGR 529
+ V + ++++ R
Sbjct: 1213 RQVEEAEEEIDR 1224
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 52.0 bits (123), Expect = 1e-06
Identities = 88/439 (20%), Positives = 187/439 (42%), Gaps = 56/439 (12%)
Query: 135 KFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAELK 194
+ E+ ++ Q KKA++ + EE +E D S++ + TI ++ +
Sbjct: 176 ELEQALSAVATQKKKADRYI-------EELTKERDALSLELYR----NTITDEELKEKNA 224
Query: 195 KASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPK 254
K ++Q V+SE ++ + ++E L+ + ++ ++ QA L
Sbjct: 225 KLQEKLQLVESEKSEIQLNVKE--------LKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 255 ILAKLSLHSSNKE---GILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAES 311
+ AKL E + ++ E+ Q + + + R E+K E
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 312 FGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVN 371
++ + + +++M E ++ KE + +R LEE +++ + + E E+++
Sbjct: 337 MRRQEEMMWEKEEKMRRQ-EEMMWEKEEK-----MRRLEEM---MWEKEEKIRELEEKMH 387
Query: 372 KREKVI-QDKTNSNIEFLLEQEKMLK--ANCVREEEKAAELQLKSKLFSFGEFNSDAQEI 428
++EK+ Q++ E + EQEK + A R+EEK E + K + QE
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR----------EQEK 437
Query: 429 LIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPK-ENVEAIERM 487
+ +KI + K+ E++ +++ + E ++ E ++ K E I +
Sbjct: 438 KMWRQEEKIHEQEKI----REEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 488 KQKEWRQ--KFRDEKMK-----EKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSG 540
++K WRQ K D++ K EK Q+E+++ EK Q +K + + +
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
Query: 541 NKQQLPLVNETKTKSQEEE 559
+Q+ + + K + QEE+
Sbjct: 554 GEQEEKMQEQEKMRRQEEK 572
Score = 49.3 bits (116), Expect = 9e-06
Identities = 85/406 (20%), Positives = 179/406 (44%), Gaps = 68/406 (16%)
Query: 133 IKKFEKDIAMRERQLKKAEKKL--QDDALAFEEFL---RENDQRSVDALKMAAQETINKL 187
I+++E+ I +E ++++ E+K+ Q++ + +E + +E R + + +E + +L
Sbjct: 309 IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRL 368
Query: 188 Q--------MTAELKKASMEVQAVKSEIAKT--EFLLREYMKYGFFLLQMSPKHWQIQQA 237
+ EL++ E + ++ + K E +RE K + K W+ ++
Sbjct: 369 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ----EQEAKMWRQEEK 424
Query: 238 LKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSL 297
+ R Q K + K + + +E I EE R ++ ++ + + +
Sbjct: 425 I-REQEEKIREQ---EKKMWRQEEKIHEQEKIREEEKRQ---EQEEMWRQEEKIREQEEI 477
Query: 298 TRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELL----QVLRELEEQN 353
R +K+K + E ++ + +++M E +E EE + + +RE EE+
Sbjct: 478 WR--QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEK---IREQEEKMWRQEEKIREQEEK- 531
Query: 354 LTLFQYSQDVDENLEEVNKREKVIQD---KTNSNIEFLLEQEKMLKANCVREEEKAAELQ 410
+ E E++ ++E+++Q+ K E + EQEKM R+EEK E +
Sbjct: 532 ---------IREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR-----RQEEKIREQE 577
Query: 411 LKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELC 470
K + + +E + + K Q K I + E+ +K+ + E ++ E
Sbjct: 578 EKIR---------EQKEKIREQEEKIWEQEEK--IREQEEMMQEQEEKMWEQEEKMCEQ- 625
Query: 471 DLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAAL 516
E +E E + R ++K W Q+ R + +EK + QE L+AA+
Sbjct: 626 ---EEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
Score = 43.1 bits (100), Expect = 7e-04
Identities = 90/485 (18%), Positives = 200/485 (41%), Gaps = 55/485 (11%)
Query: 118 DRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALK 177
DR++ E +++ + I + +LK+ KLQ+ L E + Q +V LK
Sbjct: 192 DRYIEELTKERDALSLELYRNTIT--DEELKEKNAKLQEK-LQLVESEKSEIQLNVKELK 248
Query: 178 MAAQET---INKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQ- 233
+ + + Q+ AE E+Q+V AK + + E + Q K W+
Sbjct: 249 RKLERAKLLLPQQQLQAEADHLGKELQSVS---AKLQAQVEENELWNRLNQQQEEKMWRQ 305
Query: 234 ---IQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQ 290
IQ+ ++ Q + K KI + +E + E+ + E+ ++ +
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR-RQEEMMWEKEEK 364
Query: 291 GKPSRSLTRTPEKKKSNLAESFGSEDSL----------EFLLDDEMDVDLEPALYFKEPE 340
+ + E+K L E ++ + E + + E + E ++ +E E
Sbjct: 365 MRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE-E 423
Query: 341 ELLQVLRELEEQNLTLFQYSQDVDEN-----------LEEVNKREKVIQDKTN--SNIEF 387
++ + ++ EQ +++ + + E EE+ ++E+ I+++ E
Sbjct: 424 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483
Query: 388 LLEQEKMLKAN--CVREEEKAAELQLK-----SKLFSFGEFNSDAQEILIDSLSK----- 435
+ EQEK+ K R+EEK + + K K++ E + +E + + K
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543
Query: 436 KITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQK 495
++ Q + +G+ E+ + +K+ + E ++ E + I +E E I ++K W Q+
Sbjct: 544 EMMQEQEEKMGEQEEK-MQEQEKMRRQEEKIREQEEKI----REQKEKIREQEEKIWEQE 598
Query: 496 FRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSGNKQQLPLVNETKTKS 555
+ + +E + Q+E++ EK Q +K + + +Q++ L + +
Sbjct: 599 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 658
Query: 556 QEEEY 560
+ +E+
Sbjct: 659 EHQEH 663
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 52.0 bits (123), Expect = 1e-06
Identities = 82/410 (20%), Positives = 174/410 (42%), Gaps = 47/410 (11%)
Query: 133 IKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAE 192
I++ EK + E +++ E+K+Q EE + E +++ ++ Q+ KL +
Sbjct: 452 IREREKKMREEEETMREQEEKMQKQ----EENMWEQEEKEWQQQRLPEQK--EKLWEQEK 505
Query: 193 LKKASMEVQAVKSEIAKTEFLLREYMKYGFF--LLQMSPKHWQIQQALKRAQASKSKANI 250
+++ ++ + +I E + + K + + + W+ Q+ R Q K
Sbjct: 506 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE-QEEKMRDQEQKMWDQ- 563
Query: 251 ILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAE 310
+ + K + K EE R E+ + R+ + + + R E+K E
Sbjct: 564 --EERMEKKTQEQEKKTWDQEEKMR----EEERMREREKKMREEEEMMREQEEKMQEQEE 617
Query: 311 SFGSEDSLEFLLDDEMDVDLEPALYFKEP----EELLQVLRELEEQNLTLFQYS-----Q 361
++ + +++M E +E EE + + L EQ L+++ +
Sbjct: 618 KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE 677
Query: 362 DVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEF 421
+ E E++ ++EK+ + KT + +QEKM + +RE EK
Sbjct: 678 KMQEQEEKIWEQEKM-EKKTQEQEKKTWDQEKMREEESMREREKKMR------------- 723
Query: 422 NSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENV 481
+ +E++ + K Q K+ + E++ +K+ + E ++ E L E KE +
Sbjct: 724 --EEEEMMREQEEKMQEQEEKM--QEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ--KEKL 777
Query: 482 EAIERMKQKE--WRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGR 529
E+M+++E W Q+ + +EK R Q+E+++ EK Q +K G+
Sbjct: 778 WEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQ 827
Score = 47.8 bits (112), Expect = 3e-05
Identities = 81/436 (18%), Positives = 192/436 (44%), Gaps = 39/436 (8%)
Query: 137 EKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAELKKA 196
+K++ +E Q+++ E+K+ + EE +RE ++ KM QE + ++++
Sbjct: 340 QKELREQEEQMQEQEEKMWEQ----EEKMREQEE------KMWRQEE-RLWEQEKQMREQ 388
Query: 197 SMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQAL---KRAQASKSKANIILP 253
+++ + + + + LRE + ++ K W+ + + K+ Q + K
Sbjct: 389 EQKMRDQEERMWEQDERLREKEER----MREQEKMWEQVEKMREEKKMQEQEKKTRDQEE 444
Query: 254 KILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDS----QGKPSRSLTRTPEKKKSNLA 309
K+ + + K+ + E T E+ Q ++ Q + R PE+K+ L
Sbjct: 445 KMQEEERIREREKK--MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK-LW 501
Query: 310 ESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQV-LRELEEQNLTLFQYSQDVDENL- 367
E ++ E + + E + + ++ +E + Q +RE E+Q + +D ++ +
Sbjct: 502 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 561
Query: 368 ---EEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSD 424
E + K+ + + KT E + E+E+M + EE+ + + K+ E +
Sbjct: 562 DQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621
Query: 425 AQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCD-LIESIPKENVEA 483
+E + + K Q K+ +++ + ++ + + RL E + L E + E
Sbjct: 622 QEEKMWEQEEKMQEQEEKMW---EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 678
Query: 484 IERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSGNKQ 543
++ ++K W Q+ ++K +E+++ ++ K E+++ + +KK+ + ++
Sbjct: 679 MQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQE 738
Query: 544 QLPLVNETKTKSQEEE 559
Q E K + QEEE
Sbjct: 739 Q-----EEKMQEQEEE 749
Score = 44.7 bits (104), Expect = 2e-04
Identities = 57/276 (20%), Positives = 134/276 (48%), Gaps = 23/276 (8%)
Query: 287 RDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVL 346
++ + K R+ P+ + + L E ++ E L + E + + +++ E L +
Sbjct: 249 KELKRKLERAKFLLPQVQTNTLQEEMWRQE--EELREQEKKIRKQEEKMWRQEERLREQE 306
Query: 347 RELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKA 406
++ EQ +++ + + E +E+ ++EK ++++ L EQE+ ++ +EEK
Sbjct: 307 GKMREQEEKMWRQEKRLREQEKELREQEKELREQKE-----LREQEEQMQ----EQEEKM 357
Query: 407 AELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRL 466
E + K+ E +E L + + Q K + D E+ ++L + E R+
Sbjct: 358 WEQE--EKMREQEEKMWRQEERLWEQEKQMREQEQK--MRDQEERMWEQDERLREKEERM 413
Query: 467 VELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQR-HQQERLKAALEKAVAQPKK 525
E + E + K E ++M+++E + + ++EKM+E++R ++E+ E+ + + ++
Sbjct: 414 REQEKMWEQVEKMREE--KKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEE 471
Query: 526 KLGRR--LVFHSKPPSGNKQQLPLVNETKTKSQEEE 559
K+ ++ ++ + +Q+LP E K K E+E
Sbjct: 472 KMQKQEENMWEQEEKEWQQQRLP---EQKEKLWEQE 504
Score = 42.0 bits (97), Expect = 0.002
Identities = 89/510 (17%), Positives = 211/510 (41%), Gaps = 62/510 (12%)
Query: 14 KVKDGSTKEDRPYKIFFRDLFLVKENEMAAKETEKFMNRNMKVYQKTTFSSRMKSHSYLS 73
K +D K +I R+ + +E E ++ EK + ++++ + +
Sbjct: 438 KTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 497
Query: 74 QLAFYPKRSGRSFEKFGPGPAPIPRLIE--GSDTKRTVHEFINDQRDRFLLEYALSTKRN 131
+ + ++ EK I E G + K E + +Q D+ + E +
Sbjct: 498 EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ-MWEQEEKMRDQ 556
Query: 132 TIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTA 191
K ++++ M E++ ++ EKK D EE +RE ++ KM +E + + Q
Sbjct: 557 EQKMWDQEERM-EKKTQEQEKKTWDQ----EEKMREEERMREREKKMREEEEMMREQ-EE 610
Query: 192 ELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANII 251
++++ ++Q + ++ + E ++E + + + K W+ ++ + Q
Sbjct: 611 KMQEQEEKMQEQEEKMWEQEEKMQEQEEK---MWEQEEKMWEQEEKMWEQQR-------- 659
Query: 252 LPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAES 311
LP+ KL H +E + + ++ + + + ++KK+ E
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQE-----------QEKKTWDQEK 708
Query: 312 FGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVN 371
E+S+ + E + E + ++ E++ + +++EQ +++ + + E E++
Sbjct: 709 MREEESMR---EREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMW 765
Query: 372 KREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILID 431
+++++ + K E L E EKM + + E+E+ Q E QE +
Sbjct: 766 EQQRLPEQK-----EKLWEHEKMQEQEKIWEQEEKMRDQ---------EEKMRGQEEKMR 811
Query: 432 SLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKE 491
+K+ + G E K+ + ++ E + + + E+M+ +E
Sbjct: 812 GQEEKMRGQEEKMWGQEE-----------KMWGQEEKMWGQEEKMWGQEEKMEEKMQGQE 860
Query: 492 WRQKFRDEKMK---EKQRHQQERLKAALEK 518
+ + ++EKM+ EK R Q+E+++ EK
Sbjct: 861 EKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 34.3 bits (77), Expect = 0.31
Identities = 44/215 (20%), Positives = 90/215 (41%), Gaps = 31/215 (14%)
Query: 357 FQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVR-----EEEKAAELQL 411
+ ++ ++ L V+ R K K + IE L ++ L R EE K +L
Sbjct: 175 WHFAGELQRALSAVSTRHK----KADRYIEELTKERDALSLELYRNTITNEELKKKNAEL 230
Query: 412 KSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCD 471
+ KL E ++ + L +K+ + K + + + L +++ + E L
Sbjct: 231 QEKL-PLAESEKSEIQLNVKELKRKLERA-KFLLPQVQTNTLQ--EEMWRQEEEL----- 281
Query: 472 LIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERL------KAALEKAVAQPKK 525
+E + I + ++K WRQ+ R + + K R Q+E++ EK + + +K
Sbjct: 282 ------REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEK 335
Query: 526 KLGRRLVFHSKPPSGNKQQLPL-VNETKTKSQEEE 559
+L + + +Q+ + E K + QEE+
Sbjct: 336 ELREQKELREQEEQMQEQEEKMWEQEEKMREQEEK 370
Score = 31.6 bits (70), Expect = 2.0
Identities = 42/191 (21%), Positives = 86/191 (45%), Gaps = 22/191 (11%)
Query: 340 EELLQVLRELEEQNLTLFQYSQDVDENLEEVNK---REKVIQDKTNSNIEFLLEQEKMLK 396
EEL + EL+E+ ++ N++E+ + R K + + +N L++E +
Sbjct: 221 EELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNT---LQEEMWRQ 277
Query: 397 ANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPI 456
+RE+EK Q + K++ E + + + + K Q ++ + E
Sbjct: 278 EEELREQEKKIRKQ-EEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKE------- 329
Query: 457 QKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAAL 516
L + E L E +L +E E ++ ++K W Q+ + + +EK Q+ERL
Sbjct: 330 --LREQEKELREQKEL-----REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ- 381
Query: 517 EKAVAQPKKKL 527
EK + + ++K+
Sbjct: 382 EKQMREQEQKM 392
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 52.0 bits (123), Expect = 1e-06
Identities = 102/470 (21%), Positives = 190/470 (40%), Gaps = 88/470 (18%)
Query: 122 LEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQ 181
LE + +R + K EK + R+L++ ++L++ A + N +R + KM
Sbjct: 1122 LEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRD 1181
Query: 182 ETINKLQ--------------MTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQM 227
+ LQ AEL + +Q VK ++ K + L+ M+ M
Sbjct: 1182 LEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELK--MEINDLASNM 1239
Query: 228 SPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEE-SGRTAVL------- 279
+ + +A+A+ K L L+++ ++ ++ E S + A L
Sbjct: 1240 --------ETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEF 1291
Query: 280 -----SEDASQGRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEM-DVDLEPA 333
+DA + S+GK ++ T+ E+ K L E ++ +L L D DL
Sbjct: 1292 SRQLDEKDAMVSQLSRGK--QAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLRE 1349
Query: 334 LYFKEPE-------------------------ELLQVLRELEEQNLTLFQYSQDVDENLE 368
Y +E E + +Q ELEE L Q QD +E++E
Sbjct: 1350 QYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVE 1409
Query: 369 EVNKR----EKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQ--LKSKLFSFGEFN 422
VN + EK Q N + +++ E+ A C+ ++K L + E
Sbjct: 1410 AVNSKCASLEKTKQRLQNEVEDLMIDVERS-NAACIALDKKQRNFDKVLAEWKQKYEETQ 1468
Query: 423 SDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRL-VELCDLIESIPKENV 481
++ + +S S T+++KV +A ++ L+ ++ L + L E+ DL E I +
Sbjct: 1469 AELEASQKESRSLS-TELFKV--KNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGK 1525
Query: 482 EAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRL 531
E EK+K++ H++ L+ +LE+A A + + G+ L
Sbjct: 1526 HIHEL------------EKVKKQLDHEKSELQTSLEEAEASLEHEEGKIL 1563
Score = 47.0 bits (110), Expect = 5e-05
Identities = 90/471 (19%), Positives = 196/471 (41%), Gaps = 58/471 (12%)
Query: 125 ALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETI 184
+LST+ +K ++ LK+ K LQ + E + E + + K+ Q
Sbjct: 1480 SLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDH 1539
Query: 185 NKLQMTAELKKASMEVQAVKSEIAKTEFLL--------REYMKYGFFLLQMSPKHWQIQQ 236
K ++ L++A ++ + +I + + L R+ + L Q+ H ++ +
Sbjct: 1540 EKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVE 1599
Query: 237 ALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQG--KPS 294
+++ ++ ++ +I K+ + E L + R A +E R++QG K +
Sbjct: 1600 SMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQA--AEALRNLRNTQGILKDT 1657
Query: 295 RSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKE------PEELLQV--- 345
+ + + +L E + L+ E++ +L +L E +ELL
Sbjct: 1658 QLHLDDAIRGQDDLKEQLAMVERRANLMQAEVE-ELRASLERTERGRKMAEQELLDASER 1716
Query: 346 LRELEEQNLTLFQYSQDVDENLEEVN-KREKVIQDKTNSN--IEFLLEQEKMLKANCVRE 402
++ L QN +L + ++ ++ ++ + E ++Q+ N+ + + M+ +E
Sbjct: 1717 VQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKE 1776
Query: 403 EEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKV 462
++ +A L+ K E + L ++ + ++ + G IQKL
Sbjct: 1777 QDTSAHLERMKK----------NMEQTVKDLQLRLDEAEQLAL----KGGKKQIQKL--- 1819
Query: 463 ESRLVELCDLIESIPKENVEAIERMKQKEWRQK-------------FRDEKMKEKQRHQQ 509
E+R+ EL +ES K NVEA++ +++ E R K R + + +K + +
Sbjct: 1820 EARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKV 1879
Query: 510 ERLKAALEKAVAQPKKKLGR-RLVFHSKPPSGNKQQL--PLVNETKTKSQE 557
+ K E+A Q L + R + H + + + VN+ + KS+E
Sbjct: 1880 KAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSRE 1930
Score = 31.2 bits (69), Expect = 2.6
Identities = 45/201 (22%), Positives = 90/201 (44%), Gaps = 15/201 (7%)
Query: 330 LEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLL 389
++P L E E+ + ++E E+ ++ + LEE K ++Q+K + ++
Sbjct: 840 IKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEE--KMVTLMQEKNDLQLQVQA 897
Query: 390 EQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAE 449
E + + A ++ ++QL++K+ E D +EI + +KK ++ C +
Sbjct: 898 EADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKK 956
Query: 450 D-DGLNPIQKLV---------KVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDE 499
D D L V KV++ E+ L E+I K E ++ Q+ +Q D
Sbjct: 957 DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKE--KKALQEAHQQTLDDL 1014
Query: 500 KMKEKQRHQQERLKAALEKAV 520
+M+E + + + K LE+ V
Sbjct: 1015 QMEEDKVNTLTKAKTKLEQQV 1035
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 51.6 bits (122), Expect = 2e-06
Identities = 76/389 (19%), Positives = 165/389 (42%), Gaps = 30/389 (7%)
Query: 135 KFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAELK 194
+ E+ ++ Q KKA++ + EE +E D S++ + + K + A+L+
Sbjct: 176 ELEQALSAVATQKKKADRYI-------EELTKERDALSLELYRNTITDEELK-EKNAKLQ 227
Query: 195 KASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPK 254
+ V++ KSEI L+ ++ LL + K Q+ +K + +
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 287
Query: 255 ILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESFGS 314
L+ +E + + + E + + + + EK + +
Sbjct: 288 NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEK 347
Query: 315 EDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKRE 374
E+ + +EM + E + +E E + + ++ Q +++ + + E E+++++E
Sbjct: 348 EEKMR--RQEEMMWEKEEKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 404
Query: 375 KVI-QDKTNSNIEFLLEQEKMLK--ANCVREEEKAAELQLKSKLFSFGEFNSDAQEILID 431
K+ Q++ E + EQEK + A R+EEK E + K + QE +
Sbjct: 405 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR----------EQEKKMW 454
Query: 432 SLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPK--ENVEAIERMKQ 489
+KI + K+ E++ +++ + E ++ E ++ K E E I + ++
Sbjct: 455 RQEEKIHEQEKI----REEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE 510
Query: 490 KEWRQKFRDEKMKEKQRHQQERLKAALEK 518
K WRQ+ + + +EK R Q+E++ EK
Sbjct: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEK 539
Score = 47.8 bits (112), Expect = 3e-05
Identities = 86/474 (18%), Positives = 194/474 (40%), Gaps = 44/474 (9%)
Query: 118 DRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALK 177
DR++ E +++ + I + +LK+ KLQ+ L E + Q +V LK
Sbjct: 192 DRYIEELTKERDALSLELYRNTIT--DEELKEKNAKLQEK-LQLVESEKSEIQLNVKELK 248
Query: 178 MAAQET---INKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQ- 233
+ + + Q+ AE E+Q+V AK + + E + Q K W+
Sbjct: 249 RKLERAKLLLPQQQLQAEADHLGKELQSVS---AKLQAQVEENELWNRLNQQQEEKMWRQ 305
Query: 234 ---IQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQ 290
IQ+ ++ Q + K KI + +E + E+ + E + +
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 291 GKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVD-LEPALYFKEPEELLQVLREL 349
+ + EK + + E+ + L + + + + ++ EE ++ +
Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 425
Query: 350 EEQNLTLFQYSQDVDENLEEVNKREKVI---------------QDKTNSNIEFLLEQEKM 394
+EQ +++ + + E E++ ++EK + ++K E ++EK+
Sbjct: 426 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 485
Query: 395 LKANCV-REEEKAAELQLK-----SKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDA 448
+ + R++EK E + K K++ E + +E + + K Q K+ +
Sbjct: 486 HEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE 545
Query: 449 ---EDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQ 505
E++ ++ +K+ + E R + E E I ++K WRQ+ + + +EK+
Sbjct: 546 MWREEEKMHEQEKIWEEEKRQEQ-----EDKMWRQEEKIREQEEKVWRQEEKIREQEEKR 600
Query: 506 RHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSGNKQQLPLVNETKTKSQEEE 559
+ Q+E++ EK + + ++K+ + + ++Q + E + K E+E
Sbjct: 601 QEQEEKMWKQEEK-IREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQE 653
Score = 45.8 bits (107), Expect = 1e-04
Identities = 74/414 (17%), Positives = 181/414 (43%), Gaps = 31/414 (7%)
Query: 116 QRDRFLLEYALSTKRNTIKKFEKDIAMR---ERQLKKAEKKLQDDALAFE--EFLRENDQ 170
+++ + E +R +EK+ MR E +K EK + + + +E E +RE ++
Sbjct: 339 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 398
Query: 171 RSVDALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPK 230
+ + K+ QE K Q ++++ Q ++++ + E +RE + + + K
Sbjct: 399 KMHEQEKIREQE--EKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEK---IREQEKK 452
Query: 231 HWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQ 290
W+ ++ + + + + + + + +E I + + E + +
Sbjct: 453 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKV 512
Query: 291 GKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELE 350
+ + EK + + + E+ + +EM + E +E + + +
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIRE--QEEMWREEEKM----HEQEKIWEEEKRQ 566
Query: 351 EQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKAN-CVREEEKAAEL 409
EQ +++ + + E E+V ++E+ I+++ E ++EKM K +RE+E+ +
Sbjct: 567 EQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQE---QEEKMWKQEEKIREQEEKIQE 623
Query: 410 QLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVC-----IGDAEDDGLNPIQKLVKVES 464
Q + K+ E + +E+ + K Q K+C + + E+ +K+ + E
Sbjct: 624 Q-EEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682
Query: 465 RLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEK 518
++ E + I +E E ++ ++K W Q+ + + +EK + Q+E+++ EK
Sbjct: 683 KIREQEEKI----REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732
Score = 45.4 bits (106), Expect = 1e-04
Identities = 72/399 (18%), Positives = 173/399 (43%), Gaps = 25/399 (6%)
Query: 116 QRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKL---QDDALAFEEFLRENDQRS 172
+++ + E +R +EK+ +RE + K E++ Q++ EE +RE ++R
Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 426
Query: 173 VDALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHW 232
KM QE + Q ++++ ++ + +I + E + E + Q + W
Sbjct: 427 EQEAKMWRQEEKIREQ-EEKIREQEKKMWRQEEKIHEQEKIREEEKR------QEQEEMW 479
Query: 233 QIQQALKRAQA---SKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDS 289
+ ++ + + K K + KI + +E I E+ + E+ ++
Sbjct: 480 RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE-QEEKMWRQEE 538
Query: 290 QGKPSRSLTRTPEK--KKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLR 347
+ + + R EK ++ + E ++ + + E + + +++ E++ +
Sbjct: 539 KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE 598
Query: 348 ELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAA 407
+ +EQ +++ + + E E++ ++E+ I+++ E + EQE+M + + E+
Sbjct: 599 KRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE----EKIREQEEMTQEQEEKMGEQEE 654
Query: 408 ELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLV 467
++ + + E QE I KKI + + I + E+ +K+ + E ++
Sbjct: 655 KMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEK-IREQEEMMQEQEEKMWEQEEKMC 713
Query: 468 ELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQR 506
E E +E E + R ++K W Q+ R + +EK +
Sbjct: 714 EQ----EEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Score = 42.0 bits (97), Expect = 0.002
Identities = 79/450 (17%), Positives = 189/450 (42%), Gaps = 49/450 (10%)
Query: 133 IKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAE 192
I+++E+ I +E ++++ E+K+++ E+ R+ + KM QE + +
Sbjct: 309 IQEWEEKIQEQEEKIREQEEKIREQE---EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 193 LKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIIL 252
++ M + + + E + + K +M + +Q KR + K +
Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 425
Query: 253 PKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESF 312
+ AK+ +E I E+ + + ++ R + + R EK++ E +
Sbjct: 426 QEQEAKMW---RQEEKIREQEEK--IREQEKKMWRQEEKIHEQEKIREEEKRQEQ-EEMW 479
Query: 313 GSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNK 372
E+ + E +++ E++ + ++ +Q +++ + + E E++ +
Sbjct: 480 RQEEKIH-----------EQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE 528
Query: 373 REKVI---QDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLK-----SKLFSFGEFNSD 424
+E+ + ++K E E+EKM + + EEEK E + K K+ E
Sbjct: 529 QEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWR 588
Query: 425 AQEILIDSLSKKITQVYKVC-----IGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKE 479
+E + + K+ Q K+ I + E+ +K+ + E ++ E ++ + ++
Sbjct: 589 QEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEK 648
Query: 480 NVEAIERMKQKE----------WRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGR 529
E E+M ++E WRQ+ + + ++K R Q+E+++ E Q +K
Sbjct: 649 MGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK---- 704
Query: 530 RLVFHSKPPSGNKQQLPLVNETKTKSQEEE 559
++ + +++ E K + QEE+
Sbjct: 705 --MWEQEEKMCEQEEKMQEQEEKMRRQEEK 732
Score = 41.2 bits (95), Expect = 0.003
Identities = 54/244 (22%), Positives = 117/244 (47%), Gaps = 28/244 (11%)
Query: 329 DLEPALYFKEP--EELLQVLRELEEQNLTLFQYSQDVDENLEEV----NKREKVIQDKTN 382
+L+ ALY+ + ++L R+L + ++++ ++++ L V K ++ I++ T
Sbjct: 141 ELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTK 200
Query: 383 SNIEFLLEQEKMLKANCVREEE---KAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQ 439
LE L N + +EE K A+LQ K +L E ++ + L +K+ +
Sbjct: 201 ERDALSLE----LYRNTITDEELKEKNAKLQEKLQLV---ESEKSEIQLNVKELKRKLER 253
Query: 440 VYKVCIGD----AEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQK 495
K+ + AE D L ++L V ++L + E + N ++ ++K WRQ+
Sbjct: 254 A-KLLLPQQQLQAEADHLG--KELQSVSAKLQAQVEENELWNRLN----QQQEEKMWRQE 306
Query: 496 FRDEKMKEKQRHQQERLKAALEKAVAQPKK-KLGRRLVFHSKPPSGNKQQLPLVNETKTK 554
+ ++ +EK + Q+E+++ EK Q +K + +++ + ++++ E K +
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366
Query: 555 SQEE 558
QEE
Sbjct: 367 RQEE 370
Score = 37.0 bits (84), Expect = 0.048
Identities = 54/306 (17%), Positives = 127/306 (41%), Gaps = 47/306 (15%)
Query: 111 EFINDQRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAF---EEFLRE 167
E I++Q + + + + + I+K E+ + +E ++++ E+K+++ EE +RE
Sbjct: 483 EKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIRE 542
Query: 168 NDQRSVDALKMAAQETI----NKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFF 223
++ + KM QE I + + ++ + +++ + ++ + E +RE +
Sbjct: 543 QEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEK--- 599
Query: 224 LLQMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDA 283
+ K W+ ++ + R Q K + +E I E+ + E
Sbjct: 600 RQEQEEKMWKQEEKI-REQEEKIQ----------------EQEEKIREQEEKIREQEEMT 642
Query: 284 SQGRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELL 343
+ + G+ + EK + + E+ + E +E EE +
Sbjct: 643 QEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR-----------EQEKKIREQEEKI 691
Query: 344 QVLRE-LEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVRE 402
+ E ++EQ +++ + + E E++ ++E +K E + EQE L+ ++
Sbjct: 692 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE----EKMRRQEEKMWEQEVRLR----QQ 743
Query: 403 EEKAAE 408
EEK E
Sbjct: 744 EEKMQE 749
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 51.6 bits (122), Expect = 2e-06
Identities = 93/468 (19%), Positives = 181/468 (38%), Gaps = 89/468 (19%)
Query: 122 LEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQ 181
LE L +R+ I + EK+I E QL E+F E + ++ + ++ Q
Sbjct: 2187 LEVQLQAERDAIDRKEKEITNLEEQL--------------EQFREELENKNEEVQQLHMQ 2232
Query: 182 ETINKLQMTAELKKASMEVQAVKSEIAKTEFLLRE---------YMKYGFFLLQMSPKHW 232
I K + T L++ E + K ++ K ++E ++ +G F + K
Sbjct: 2233 LEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEV 2292
Query: 233 QIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGK 292
+I Q Q +K + + KI + E I + + L D + ++ +
Sbjct: 2293 EIDQL--NEQVTKLQQQL---KITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREE 2347
Query: 293 PSRSLTRTPEKKKSNLAESFGSEDSLEF--------LLDDEMDVDLEPALYFKEP----- 339
L EK + LA + G + S+ L ++DV + L ++
Sbjct: 2348 EIEQLNEVIEKLQQELA-NIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETAN 2406
Query: 340 EELLQVLRELEEQNLTLFQYSQD---VDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLK 396
EE+ + L+E N + Q +Q+ + E V K + + ++ N I+ L + + L+
Sbjct: 2407 EEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELE 2466
Query: 397 ANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPI 456
+ K+ E Q K F E++G I
Sbjct: 2467 VVLTEDALKSLENQTYFKSF--------------------------------EENGKGSI 2494
Query: 457 QKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEK----QRHQQERL 512
+ +E+RL++L + + E + +++K + + +F E +++K Q+ +E++
Sbjct: 2495 ---INLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKV 2551
Query: 513 KAALE-----KAVAQPKKKLGRRLVFHSKPPSGNKQQLPLVNETKTKS 555
AAL +AV + K S+P N Q L + E + S
Sbjct: 2552 AAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGS 2599
Score = 48.9 bits (115), Expect = 1e-05
Identities = 93/487 (19%), Positives = 202/487 (41%), Gaps = 84/487 (17%)
Query: 122 LEYALSTKRNTIKKFEKDIA---MRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKM 178
L+ + K IK + ++ +ERQ + K+L ++ ++ Q D ++
Sbjct: 362 LQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQR 421
Query: 179 AAQETINKL-QMTAELKKA-SMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKH-WQIQ 235
QET KL Q+ AEL + ++ +K E L+R++M + +M +H +++
Sbjct: 422 MEQETQRKLEQLRAELDEMYGQQIVQMKQE------LIRQHMAQ---MEEMKTRHKGEME 472
Query: 236 QALKR------AQASKSKANIILPKILAKLSLHSSNKEGILEESG-----------RTAV 278
AL+ + N+ + ++ KL +S KE + EE G +
Sbjct: 473 NALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLED 532
Query: 279 LSEDASQGRDSQGKPSRSLTR-------------TPEKKKSNLAESFGSEDSLEFLLDDE 325
L E+ S R+ + +++ T E K+ + + S LE + E
Sbjct: 533 LVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAE 592
Query: 326 M-DVDLEPALYFKEPEELLQVLRELEEQNL------TLFQYSQDVDENLEEVNKREKVIQ 378
+ + ++ + KE +L + E +E L LF + +++ + E++ ++
Sbjct: 593 VTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINI 652
Query: 379 DKTNSNIEFLLEQE------KMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDS 432
+K N+ +Q+ +M + + EK + +++L D Q+ L++S
Sbjct: 653 EKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNS 712
Query: 433 LSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEW 492
S+++T +N +QK + +++ KE + +++ +
Sbjct: 713 KSEEMTL------------QINELQKEI----------EILRQEEKEKGTLEQEVQELQL 750
Query: 493 RQKFRDEKMKEKQRHQQERLK--AALEKAVAQPKKKLGRRLVFHSKPPSGNKQQLPLVNE 550
+ + +++MKEK+ QE+ A + KK L L H+ P +++L ++
Sbjct: 751 KTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHT--PVSQEERLIFLDS 808
Query: 551 TKTKSQE 557
K+KS++
Sbjct: 809 IKSKSKD 815
Score = 43.1 bits (100), Expect = 7e-04
Identities = 97/465 (20%), Positives = 197/465 (42%), Gaps = 68/465 (14%)
Query: 126 LSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETIN 185
LS R I++ + IA +E +L +A K L E + ++ R LK A+ T
Sbjct: 537 LSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNY 596
Query: 186 K--LQMTAELKKASM----EVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALK 239
K L+M + K A + E Q + E +T+ L + + +H + LK
Sbjct: 597 KIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLK 656
Query: 240 RAQASKSKANI--ILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQ----GKP 293
K I + ++ K+ K+ ++ + + + + S+ +D Q
Sbjct: 657 DNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLIL---EISKLKDLQQSLVNSK 713
Query: 294 SRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEM-DVDLEPALYFKEPEE----LLQVLRE 348
S +T + + + E E+ + L+ E+ ++ L+ L K+ +E L + +
Sbjct: 714 SEEMTLQINELQKEI-EILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQ 772
Query: 349 LEEQNLTLFQYSQDVDENLE---EVNKREKVI-----QDKTNSN-----IEFLLEQEKML 395
LE +N L + +++ L+ V++ E++I + K+ + IE L+E+ + L
Sbjct: 773 LEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDL 832
Query: 396 KANCVREEEKAAELQLKSKLFSFGE--FNSDAQEI-------------LIDSLSKKITQV 440
K C++ E E++ + FSF E F + QE+ L DS +K+ +
Sbjct: 833 KQQCIQLNE---EIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELE- 888
Query: 441 YKVCIGDAEDD----GLNPIQKLVKV------ESRLVELCDLIESIPKENVEAIERM--- 487
YK + ++ +NP +K ++ + E ++ E + K+ E +E++
Sbjct: 889 YKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVT 948
Query: 488 --KQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRR 530
++ E Q+ D + KQ+H + K++ Q K+++ R
Sbjct: 949 KREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLR 993
Score = 35.0 bits (79), Expect = 0.18
Identities = 74/374 (19%), Positives = 142/374 (37%), Gaps = 53/374 (14%)
Query: 146 QLKKAEKKLQDDALAFEEFLREND-QRSVDALKMAAQETINKLQMTAELKKASMEVQAVK 204
+L KAE + D A E+ L E Q D + QE + EL+ ++Q +
Sbjct: 1916 ELSKAEGVI--DGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEER 1973
Query: 205 SEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSS 264
+++ +E MK + P Q+ Q ++ K + K+ L
Sbjct: 1974 ELLSRQ----KEAMK-----AEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVK 2024
Query: 265 NKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDD 324
E +EE + E T + ++ N A E +FL D
Sbjct: 2025 ALEIDVEEQVSRFIELEQEKN------------TELMDLRQQNQALEKQLEKMRKFL--D 2070
Query: 325 EMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSN 384
E +D E E + Q +++LE+Q + ++ + EV + +++KT+
Sbjct: 2071 EQAIDRE-----HERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKC 2125
Query: 385 IEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVC 444
E LL +E+ L+ + E+ +L+ + + A + D+ K
Sbjct: 2126 SELLLSKEQ-LQRDIQERNEEIEKLEFRVREL------EQALLVSADTFQK--------- 2169
Query: 445 IGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEK 504
+ D + G + + +E +L D I+ KE E+++Q FR+E +
Sbjct: 2170 VEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQ------FREELENKN 2223
Query: 505 QRHQQERLKAALEK 518
+ QQ ++ ++K
Sbjct: 2224 EEVQQLHMQLEIQK 2237
Score = 32.0 bits (71), Expect = 1.6
Identities = 41/199 (20%), Positives = 87/199 (43%), Gaps = 9/199 (4%)
Query: 336 FKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLE-QEKM 394
F++ +E + L+ EE L + S+ ++ E++K E VI + F + QEK
Sbjct: 1883 FRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKT 1942
Query: 395 LKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILID-SLSKKITQVYKVCIGDAEDDGL 453
+ + +E A +L+ E ++ Q+I + L + + K G E L
Sbjct: 1943 DIIDRLEQELLCASNRLQ-------ELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLL 1995
Query: 454 NPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLK 513
+KL+K + + + + ++ V+A+E +++ + E+ K + +
Sbjct: 1996 QETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQN 2055
Query: 514 AALEKAVAQPKKKLGRRLV 532
ALEK + + +K L + +
Sbjct: 2056 QALEKQLEKMRKFLDEQAI 2074
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 51.6 bits (122), Expect = 2e-06
Identities = 93/468 (19%), Positives = 181/468 (38%), Gaps = 89/468 (19%)
Query: 122 LEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQ 181
LE L +R+ I + EK+I E QL E+F E + ++ + ++ Q
Sbjct: 2179 LEVQLQAERDAIDRKEKEITNLEEQL--------------EQFREELENKNEEVQQLHMQ 2224
Query: 182 ETINKLQMTAELKKASMEVQAVKSEIAKTEFLLRE---------YMKYGFFLLQMSPKHW 232
I K + T L++ E + K ++ K ++E ++ +G F + K
Sbjct: 2225 LEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEV 2284
Query: 233 QIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGK 292
+I Q Q +K + + KI + E I + + L D + ++ +
Sbjct: 2285 EIDQL--NEQVTKLQQQL---KITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREE 2339
Query: 293 PSRSLTRTPEKKKSNLAESFGSEDSLEF--------LLDDEMDVDLEPALYFKEP----- 339
L EK + LA + G + S+ L ++DV + L ++
Sbjct: 2340 EIEQLNEVIEKLQQELA-NIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETAN 2398
Query: 340 EELLQVLRELEEQNLTLFQYSQD---VDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLK 396
EE+ + L+E N + Q +Q+ + E V K + + ++ N I+ L + + L+
Sbjct: 2399 EEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELE 2458
Query: 397 ANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPI 456
+ K+ E Q K F E++G I
Sbjct: 2459 VVLTEDALKSLENQTYFKSF--------------------------------EENGKGSI 2486
Query: 457 QKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEK----QRHQQERL 512
+ +E+RL++L + + E + +++K + + +F E +++K Q+ +E++
Sbjct: 2487 ---INLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKV 2543
Query: 513 KAALE-----KAVAQPKKKLGRRLVFHSKPPSGNKQQLPLVNETKTKS 555
AAL +AV + K S+P N Q L + E + S
Sbjct: 2544 AAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGS 2591
Score = 48.9 bits (115), Expect = 1e-05
Identities = 93/487 (19%), Positives = 202/487 (41%), Gaps = 84/487 (17%)
Query: 122 LEYALSTKRNTIKKFEKDIA---MRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKM 178
L+ + K IK + ++ +ERQ + K+L ++ ++ Q D ++
Sbjct: 362 LQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQR 421
Query: 179 AAQETINKL-QMTAELKKA-SMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKH-WQIQ 235
QET KL Q+ AEL + ++ +K E L+R++M + +M +H +++
Sbjct: 422 MEQETQRKLEQLRAELDEMYGQQIVQMKQE------LIRQHMAQ---MEEMKTRHKGEME 472
Query: 236 QALKR------AQASKSKANIILPKILAKLSLHSSNKEGILEESG-----------RTAV 278
AL+ + N+ + ++ KL +S KE + EE G +
Sbjct: 473 NALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLED 532
Query: 279 LSEDASQGRDSQGKPSRSLTR-------------TPEKKKSNLAESFGSEDSLEFLLDDE 325
L E+ S R+ + +++ T E K+ + + S LE + E
Sbjct: 533 LVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAE 592
Query: 326 M-DVDLEPALYFKEPEELLQVLRELEEQNL------TLFQYSQDVDENLEEVNKREKVIQ 378
+ + ++ + KE +L + E +E L LF + +++ + E++ ++
Sbjct: 593 VTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINI 652
Query: 379 DKTNSNIEFLLEQE------KMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDS 432
+K N+ +Q+ +M + + EK + +++L D Q+ L++S
Sbjct: 653 EKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNS 712
Query: 433 LSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEW 492
S+++T +N +QK + +++ KE + +++ +
Sbjct: 713 KSEEMTL------------QINELQKEI----------EILRQEEKEKGTLEQEVQELQL 750
Query: 493 RQKFRDEKMKEKQRHQQERLK--AALEKAVAQPKKKLGRRLVFHSKPPSGNKQQLPLVNE 550
+ + +++MKEK+ QE+ A + KK L L H+ P +++L ++
Sbjct: 751 KTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHT--PVSQEERLIFLDS 808
Query: 551 TKTKSQE 557
K+KS++
Sbjct: 809 IKSKSKD 815
Score = 43.1 bits (100), Expect = 7e-04
Identities = 97/465 (20%), Positives = 197/465 (42%), Gaps = 68/465 (14%)
Query: 126 LSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETIN 185
LS R I++ + IA +E +L +A K L E + ++ R LK A+ T
Sbjct: 537 LSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNY 596
Query: 186 K--LQMTAELKKASM----EVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALK 239
K L+M + K A + E Q + E +T+ L + + +H + LK
Sbjct: 597 KIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLK 656
Query: 240 RAQASKSKANI--ILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQ----GKP 293
K I + ++ K+ K+ ++ + + + + S+ +D Q
Sbjct: 657 DNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLIL---EISKLKDLQQSLVNSK 713
Query: 294 SRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEM-DVDLEPALYFKEPEE----LLQVLRE 348
S +T + + + E E+ + L+ E+ ++ L+ L K+ +E L + +
Sbjct: 714 SEEMTLQINELQKEI-EILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQ 772
Query: 349 LEEQNLTLFQYSQDVDENLE---EVNKREKVI-----QDKTNSN-----IEFLLEQEKML 395
LE +N L + +++ L+ V++ E++I + K+ + IE L+E+ + L
Sbjct: 773 LEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDL 832
Query: 396 KANCVREEEKAAELQLKSKLFSFGE--FNSDAQEI-------------LIDSLSKKITQV 440
K C++ E E++ + FSF E F + QE+ L DS +K+ +
Sbjct: 833 KQQCIQLNE---EIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELE- 888
Query: 441 YKVCIGDAEDD----GLNPIQKLVKV------ESRLVELCDLIESIPKENVEAIERM--- 487
YK + ++ +NP +K ++ + E ++ E + K+ E +E++
Sbjct: 889 YKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVT 948
Query: 488 --KQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRR 530
++ E Q+ D + KQ+H + K++ Q K+++ R
Sbjct: 949 KREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLR 993
Score = 34.3 bits (77), Expect = 0.31
Identities = 73/375 (19%), Positives = 141/375 (37%), Gaps = 63/375 (16%)
Query: 146 QLKKAEKKLQDDALAFEEFLREND-QRSVDALKMAAQETINKLQMTAELKKASMEVQAVK 204
+L KAE + D A E+ L E Q D + QE + EL+ ++Q +
Sbjct: 1916 ELSKAEGVI--DGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEER 1973
Query: 205 SEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSS 264
+++ +E MK + P Q+ Q ++ K + K+ L
Sbjct: 1974 ELLSRQ----KEAMK-----AEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVK 2024
Query: 265 NKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDD 324
E +EE + E T + ++ N A E +FL D
Sbjct: 2025 ALEIDVEEQVSRFIELEQEKN------------TELMDLRQQNQALEKQLEKMRKFL--D 2070
Query: 325 EMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSN 384
E +D E E + Q +++LE+Q + ++ + EV + +++KT+
Sbjct: 2071 EQAIDRE-----HERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKC 2125
Query: 385 IEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYK-V 443
E LL +E++ + R EE I+ L ++ ++ + +
Sbjct: 2126 SELLLSKEQLQRDIQERNEE-------------------------IEKLEFRVRELEQAL 2160
Query: 444 CIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKE 503
+ D + G + + +E +L D I+ KE E+++Q FR+E +
Sbjct: 2161 LVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQ------FREELENK 2214
Query: 504 KQRHQQERLKAALEK 518
+ QQ ++ ++K
Sbjct: 2215 NEEVQQLHMQLEIQK 2229
Score = 32.0 bits (71), Expect = 1.6
Identities = 41/199 (20%), Positives = 87/199 (43%), Gaps = 9/199 (4%)
Query: 336 FKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLE-QEKM 394
F++ +E + L+ EE L + S+ ++ E++K E VI + F + QEK
Sbjct: 1883 FRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKT 1942
Query: 395 LKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILID-SLSKKITQVYKVCIGDAEDDGL 453
+ + +E A +L+ E ++ Q+I + L + + K G E L
Sbjct: 1943 DIIDRLEQELLCASNRLQ-------ELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLL 1995
Query: 454 NPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLK 513
+KL+K + + + + ++ V+A+E +++ + E+ K + +
Sbjct: 1996 QETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQN 2055
Query: 514 AALEKAVAQPKKKLGRRLV 532
ALEK + + +K L + +
Sbjct: 2056 QALEKQLEKMRKFLDEQAI 2074
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 51.6 bits (122), Expect = 2e-06
Identities = 103/489 (21%), Positives = 191/489 (39%), Gaps = 62/489 (12%)
Query: 101 EGSDTKRTVHEFINDQRDRFLLEYALSTKRNTIKKF--EKDIAMRERQLKKAEK-----K 153
E D K ++ ++ Q+ LE L TI + EK+ M E +A +
Sbjct: 323 ELEDIKVSLQRSVSTQK---ALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFVVTE 379
Query: 154 LQDDALAFEEFLRENDQR---SVDALKMAAQETINKLQMTAELKKAS----MEVQAVKSE 206
+ + EE LR QR + D LK+ E K E+ K + +E++ +K
Sbjct: 380 FETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKV 439
Query: 207 IAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNK 266
+ + E LL E ++ ++ ++ L+ + I L I +S
Sbjct: 440 LGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEV 499
Query: 267 EGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEM 326
+ + E + + + + + ++ LT+ S+ +LE L + +
Sbjct: 500 KDLKTELENEKLKNTELTSHCNKLSLENKELTQET------------SDMTLE-LKNQQE 546
Query: 327 DVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIE 386
D++ K+ E +L+ + L+E L + V E L++ K DK+ N
Sbjct: 547 DINNNK----KQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCN 602
Query: 387 FLLEQ--EKMLKANCVREEEKAAELQ--LKSKLFSFGEFNSDAQEILIDSLSKK---ITQ 439
L +Q K +++E KA + + +SK + E + E+ ++S +K IT
Sbjct: 603 NLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITD 662
Query: 440 VYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERM-----KQKEWRQ 494
Y+ I D + N ++++ K + E L + I K I M K K
Sbjct: 663 TYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYD 722
Query: 495 KFRDEKMKE-----KQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSGNKQQLPLVN 549
K +E+ E + +Q L+A+LE ++ K +L K+QL +
Sbjct: 723 KIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKAEL-----------LSVKKQLEIER 771
Query: 550 ETKTKSQEE 558
E K K + E
Sbjct: 772 EEKEKLKRE 780
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 51.6 bits (122), Expect = 2e-06
Identities = 65/309 (21%), Positives = 136/309 (44%), Gaps = 35/309 (11%)
Query: 279 LSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKE 338
++ D+ + ++ G S++ T P + + N E+ + +D++L + + +
Sbjct: 715 INSDSGENKEEIGSLSKTETILPPESE-NPKENDNDSGTGSTADTSSIDLNLSISSFLSK 773
Query: 339 PEELLQV-LRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEF-LLEQEKMLK 396
++ + L+E Q TL + + + + +E K++ D + E L ++++ +
Sbjct: 774 TKDSGSISLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRE 833
Query: 397 ANCVREEEKAAELQLKSKLFSFGE--FNSDAQEIL---------IDSLSKKITQVYKVC- 444
+++EE+ A+ QL SKL E F QE++ I++L K+ Q +
Sbjct: 834 LRFLQKEEQRAQQQLNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLE 893
Query: 445 -------------IGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKE 491
I ++ L+ Q ++K +R E+ + +E PKE + + + +++E
Sbjct: 894 QEHTNRLRDEAKRIKGEQEKELSKFQNMLK--NRKKEVINEVEKAPKELRKELMKRRKEE 951
Query: 492 WRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSGNKQQLPLVNET 551
Q ++ + Q+ QQE L +L+K + Q K +L + NKQQL E
Sbjct: 952 LAQSQHAQEQEFVQKQQQE-LDGSLKKIIQQQKAELAN----IERECLNNKQQLMRAREA 1006
Query: 552 KTKSQEEEY 560
EE +
Sbjct: 1007 AIWELEERH 1015
>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
sapiens]
Length = 638
Score = 50.4 bits (119), Expect = 4e-06
Identities = 58/236 (24%), Positives = 115/236 (48%), Gaps = 25/236 (10%)
Query: 288 DSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLR 347
+SQGK ++ + +K + E +E LE++ +E+ + +K ++ Q+
Sbjct: 118 ESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYI--EEISCASDQVEKYKL--DIAQLEE 173
Query: 348 ELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVRE--EEK 405
L+E+N + Q ++EN+ ++K+ + + K LLE+EK N RE E
Sbjct: 174 NLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQ-----LLEKEKEDHVNRNREHNENL 228
Query: 406 AAELQ-LKSKLFSFGEFNSDAQ--EILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKV 462
AE+Q LK K + Q E+ IDSL ++ ++ L+ QKL
Sbjct: 229 NAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKEL---------SSSLH--QKLCSF 277
Query: 463 ESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEK 518
+ +V+ +L E K+ ++ +++++QKE + + ++++E+ + + E LK EK
Sbjct: 278 QEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEK 333
Score = 40.8 bits (94), Expect = 0.003
Identities = 73/336 (21%), Positives = 135/336 (40%), Gaps = 43/336 (12%)
Query: 237 ALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTA---VLSEDASQGRDSQGKP 293
A R + S S N L K L +L+ + + E+G +LS + + R+ +
Sbjct: 35 AALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETK 94
Query: 294 SRSLTRTPEKKKS-------NLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVL 346
R + E + +L ES G LE L + ++ E E E+LL+ +
Sbjct: 95 MRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKL---VSIEKEKIDEKSETEKLLEYI 151
Query: 347 RELEEQNLTLFQYSQDV---DENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREE 403
E+ + + +Y D+ +ENL+E N ++ NI L +Q + L C +
Sbjct: 152 EEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKC-QLL 210
Query: 404 EKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVE 463
EK E + N++ Q + K + E + L QK ++++
Sbjct: 211 EKEKEDHVNRNREHNENLNAEMQNLK-----------QKFILEQQEREKLQ--QKELQID 257
Query: 464 SRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQP 523
S L + +L S+ ++ F++E +KEK ++E + E Q
Sbjct: 258 SLLQQEKELSSSLHQKLCS-------------FQEEMVKEKNLFEEELKQTLDELDKLQQ 304
Query: 524 KKKLGRRLVFHSKPPSGNKQQLPLVNETKTKSQEEE 559
K++ RLV + + ++ + + E K K +E E
Sbjct: 305 KEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAE 340
Score = 30.8 bits (68), Expect = 3.5
Identities = 71/419 (16%), Positives = 161/419 (38%), Gaps = 57/419 (13%)
Query: 122 LEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQ 181
+E L + ++++ + IA E +L EK+ D+ E+ L ++ S A +
Sbjct: 105 MEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISC-ASDQVEK 163
Query: 182 ETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRA 241
++ Q+ LK+ + E+ ++K + + +L + ++ Q+ K + + + R
Sbjct: 164 YKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEK--EKEDHVNRN 221
Query: 242 QASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTP 301
+ N + + K L +E + ++ + DS + + L+ +
Sbjct: 222 REHNENLNAEMQNLKQKFILEQQEREKLQQKELQI-----------DSLLQQEKELSSSL 270
Query: 302 EKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQ 361
+K + E E +L EEL Q L EL++
Sbjct: 271 HQKLCSFQEEMVKEKNLF-------------------EEELKQTLDELDK---------- 301
Query: 362 DVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEF 421
+ + E+ + K ++++ S E L E+ LK E EK++ ++ L ++
Sbjct: 302 -LQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGK-EAELEKSSAAHTQATLLLQEKY 359
Query: 422 NSDAQEILIDSLSKKITQVYKVCIGDAED---DGLNPIQKLVKVESRLVELCDLIESIPK 478
+S Q ++ ++ + + + ED + + +K K ++ I +
Sbjct: 360 DSMVQS--LEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATES 417
Query: 479 ENVEAIERMKQKEWRQKFRDEKMKE-------KQRHQQERLKAALEKAVAQPKKKLGRR 530
N E + + + + ++ ++KE K Q +LK E Q + + GR+
Sbjct: 418 SNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFRKQLEDEEGRK 476
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 50.4 bits (119), Expect = 4e-06
Identities = 58/236 (24%), Positives = 115/236 (48%), Gaps = 25/236 (10%)
Query: 288 DSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLR 347
+SQGK ++ + +K + E +E LE++ +E+ + +K ++ Q+
Sbjct: 205 ESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYI--EEISCASDQVEKYKL--DIAQLEE 260
Query: 348 ELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVRE--EEK 405
L+E+N + Q ++EN+ ++K+ + + K LLE+EK N RE E
Sbjct: 261 NLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQ-----LLEKEKEDHVNRNREHNENL 315
Query: 406 AAELQ-LKSKLFSFGEFNSDAQ--EILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKV 462
AE+Q LK K + Q E+ IDSL ++ ++ L+ QKL
Sbjct: 316 NAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKEL---------SSSLH--QKLCSF 364
Query: 463 ESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEK 518
+ +V+ +L E K+ ++ +++++QKE + + ++++E+ + + E LK EK
Sbjct: 365 QEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEK 420
Score = 40.8 bits (94), Expect = 0.003
Identities = 73/336 (21%), Positives = 135/336 (40%), Gaps = 43/336 (12%)
Query: 237 ALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTA---VLSEDASQGRDSQGKP 293
A R + S S N L K L +L+ + + E+G +LS + + R+ +
Sbjct: 122 AALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETK 181
Query: 294 SRSLTRTPEKKKS-------NLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVL 346
R + E + +L ES G LE L + ++ E E E+LL+ +
Sbjct: 182 MRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKL---VSIEKEKIDEKSETEKLLEYI 238
Query: 347 RELEEQNLTLFQYSQDV---DENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREE 403
E+ + + +Y D+ +ENL+E N ++ NI L +Q + L C +
Sbjct: 239 EEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKC-QLL 297
Query: 404 EKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVE 463
EK E + N++ Q + K + E + L QK ++++
Sbjct: 298 EKEKEDHVNRNREHNENLNAEMQNLK-----------QKFILEQQEREKLQ--QKELQID 344
Query: 464 SRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQP 523
S L + +L S+ ++ F++E +KEK ++E + E Q
Sbjct: 345 SLLQQEKELSSSLHQKLCS-------------FQEEMVKEKNLFEEELKQTLDELDKLQQ 391
Query: 524 KKKLGRRLVFHSKPPSGNKQQLPLVNETKTKSQEEE 559
K++ RLV + + ++ + + E K K +E E
Sbjct: 392 KEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAE 427
Score = 30.8 bits (68), Expect = 3.5
Identities = 71/419 (16%), Positives = 161/419 (38%), Gaps = 57/419 (13%)
Query: 122 LEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQ 181
+E L + ++++ + IA E +L EK+ D+ E+ L ++ S A +
Sbjct: 192 MEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISC-ASDQVEK 250
Query: 182 ETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRA 241
++ Q+ LK+ + E+ ++K + + +L + ++ Q+ K + + + R
Sbjct: 251 YKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEK--EKEDHVNRN 308
Query: 242 QASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTP 301
+ N + + K L +E + ++ + DS + + L+ +
Sbjct: 309 REHNENLNAEMQNLKQKFILEQQEREKLQQKELQI-----------DSLLQQEKELSSSL 357
Query: 302 EKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQ 361
+K + E E +L EEL Q L EL++
Sbjct: 358 HQKLCSFQEEMVKEKNLF-------------------EEELKQTLDELDK---------- 388
Query: 362 DVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEF 421
+ + E+ + K ++++ S E L E+ LK E EK++ ++ L ++
Sbjct: 389 -LQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGK-EAELEKSSAAHTQATLLLQEKY 446
Query: 422 NSDAQEILIDSLSKKITQVYKVCIGDAED---DGLNPIQKLVKVESRLVELCDLIESIPK 478
+S Q ++ ++ + + + ED + + +K K ++ I +
Sbjct: 447 DSMVQS--LEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATES 504
Query: 479 ENVEAIERMKQKEWRQKFRDEKMKE-------KQRHQQERLKAALEKAVAQPKKKLGRR 530
N E + + + + ++ ++KE K Q +LK E Q + + GR+
Sbjct: 505 SNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFRKQLEDEEGRK 563
>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
sapiens]
Length = 709
Score = 50.4 bits (119), Expect = 4e-06
Identities = 58/236 (24%), Positives = 115/236 (48%), Gaps = 25/236 (10%)
Query: 288 DSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLR 347
+SQGK ++ + +K + E +E LE++ +E+ + +K ++ Q+
Sbjct: 189 ESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYI--EEISCASDQVEKYKL--DIAQLEE 244
Query: 348 ELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVRE--EEK 405
L+E+N + Q ++EN+ ++K+ + + K LLE+EK N RE E
Sbjct: 245 NLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQ-----LLEKEKEDHVNRNREHNENL 299
Query: 406 AAELQ-LKSKLFSFGEFNSDAQ--EILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKV 462
AE+Q LK K + Q E+ IDSL ++ ++ L+ QKL
Sbjct: 300 NAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKEL---------SSSLH--QKLCSF 348
Query: 463 ESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEK 518
+ +V+ +L E K+ ++ +++++QKE + + ++++E+ + + E LK EK
Sbjct: 349 QEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEK 404
Score = 41.2 bits (95), Expect = 0.003
Identities = 80/373 (21%), Positives = 150/373 (40%), Gaps = 46/373 (12%)
Query: 203 VKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALK---RAQASKSKANIILPKILAKL 259
VKS +K LL+E + + + +++ L R + S S N L K L +L
Sbjct: 69 VKSSESKIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIEL 128
Query: 260 SLHSSNKEGILEESGRTA---VLSEDASQGRDSQGKPSRSLTRTPEKKKS-------NLA 309
+ + + E+G +LS + + R+ + R + E + +L
Sbjct: 129 TRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLE 188
Query: 310 ESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDV---DEN 366
ES G LE L + ++ E E E+LL+ + E+ + + +Y D+ +EN
Sbjct: 189 ESQGKIAQLEGKL---VSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEEN 245
Query: 367 LEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQ 426
L+E N ++ NI L +Q + L C + EK E + N++ Q
Sbjct: 246 LKEKNDEILSLKQSLEENIVILSKQVEDLNVKC-QLLEKEKEDHVNRNREHNENLNAEMQ 304
Query: 427 EILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIER 486
+ K + E + L QK ++++S L + +L S+ ++
Sbjct: 305 NLK-----------QKFILEQQEREKLQ--QKELQIDSLLQQEKELSSSLHQKLCS---- 347
Query: 487 MKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSGNKQQLP 546
F++E +KEK ++E + E Q K++ RLV + + ++ +
Sbjct: 348 ---------FQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEEL 398
Query: 547 LVNETKTKSQEEE 559
+ E K K +E E
Sbjct: 399 KLLEEKLKGKEAE 411
Score = 30.8 bits (68), Expect = 3.5
Identities = 71/419 (16%), Positives = 161/419 (38%), Gaps = 57/419 (13%)
Query: 122 LEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQ 181
+E L + ++++ + IA E +L EK+ D+ E+ L ++ S A +
Sbjct: 176 MEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISC-ASDQVEK 234
Query: 182 ETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRA 241
++ Q+ LK+ + E+ ++K + + +L + ++ Q+ K + + + R
Sbjct: 235 YKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEK--EKEDHVNRN 292
Query: 242 QASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTP 301
+ N + + K L +E + ++ + DS + + L+ +
Sbjct: 293 REHNENLNAEMQNLKQKFILEQQEREKLQQKELQI-----------DSLLQQEKELSSSL 341
Query: 302 EKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQ 361
+K + E E +L EEL Q L EL++
Sbjct: 342 HQKLCSFQEEMVKEKNLF-------------------EEELKQTLDELDK---------- 372
Query: 362 DVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEF 421
+ + E+ + K ++++ S E L E+ LK E EK++ ++ L ++
Sbjct: 373 -LQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGK-EAELEKSSAAHTQATLLLQEKY 430
Query: 422 NSDAQEILIDSLSKKITQVYKVCIGDAED---DGLNPIQKLVKVESRLVELCDLIESIPK 478
+S Q ++ ++ + + + ED + + +K K ++ I +
Sbjct: 431 DSMVQS--LEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATES 488
Query: 479 ENVEAIERMKQKEWRQKFRDEKMKE-------KQRHQQERLKAALEKAVAQPKKKLGRR 530
N E + + + + ++ ++KE K Q +LK E Q + + GR+
Sbjct: 489 SNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFRKQLEDEEGRK 547
>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
sapiens]
Length = 724
Score = 50.4 bits (119), Expect = 4e-06
Identities = 58/236 (24%), Positives = 115/236 (48%), Gaps = 25/236 (10%)
Query: 288 DSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLR 347
+SQGK ++ + +K + E +E LE++ +E+ + +K ++ Q+
Sbjct: 204 ESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYI--EEISCASDQVEKYKL--DIAQLEE 259
Query: 348 ELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVRE--EEK 405
L+E+N + Q ++EN+ ++K+ + + K LLE+EK N RE E
Sbjct: 260 NLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQ-----LLEKEKEDHVNRNREHNENL 314
Query: 406 AAELQ-LKSKLFSFGEFNSDAQ--EILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKV 462
AE+Q LK K + Q E+ IDSL ++ ++ L+ QKL
Sbjct: 315 NAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKEL---------SSSLH--QKLCSF 363
Query: 463 ESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEK 518
+ +V+ +L E K+ ++ +++++QKE + + ++++E+ + + E LK EK
Sbjct: 364 QEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEK 419
Score = 40.8 bits (94), Expect = 0.003
Identities = 73/336 (21%), Positives = 135/336 (40%), Gaps = 43/336 (12%)
Query: 237 ALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTA---VLSEDASQGRDSQGKP 293
A R + S S N L K L +L+ + + E+G +LS + + R+ +
Sbjct: 121 AALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETK 180
Query: 294 SRSLTRTPEKKKS-------NLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVL 346
R + E + +L ES G LE L + ++ E E E+LL+ +
Sbjct: 181 MRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKL---VSIEKEKIDEKSETEKLLEYI 237
Query: 347 RELEEQNLTLFQYSQDV---DENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREE 403
E+ + + +Y D+ +ENL+E N ++ NI L +Q + L C +
Sbjct: 238 EEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKC-QLL 296
Query: 404 EKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVE 463
EK E + N++ Q + K + E + L QK ++++
Sbjct: 297 EKEKEDHVNRNREHNENLNAEMQNLK-----------QKFILEQQEREKLQ--QKELQID 343
Query: 464 SRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQP 523
S L + +L S+ ++ F++E +KEK ++E + E Q
Sbjct: 344 SLLQQEKELSSSLHQKLCS-------------FQEEMVKEKNLFEEELKQTLDELDKLQQ 390
Query: 524 KKKLGRRLVFHSKPPSGNKQQLPLVNETKTKSQEEE 559
K++ RLV + + ++ + + E K K +E E
Sbjct: 391 KEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAE 426
Score = 30.8 bits (68), Expect = 3.5
Identities = 71/419 (16%), Positives = 161/419 (38%), Gaps = 57/419 (13%)
Query: 122 LEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQ 181
+E L + ++++ + IA E +L EK+ D+ E+ L ++ S A +
Sbjct: 191 MEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISC-ASDQVEK 249
Query: 182 ETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRA 241
++ Q+ LK+ + E+ ++K + + +L + ++ Q+ K + + + R
Sbjct: 250 YKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEK--EKEDHVNRN 307
Query: 242 QASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTP 301
+ N + + K L +E + ++ + DS + + L+ +
Sbjct: 308 REHNENLNAEMQNLKQKFILEQQEREKLQQKELQI-----------DSLLQQEKELSSSL 356
Query: 302 EKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQ 361
+K + E E +L EEL Q L EL++
Sbjct: 357 HQKLCSFQEEMVKEKNLF-------------------EEELKQTLDELDK---------- 387
Query: 362 DVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEF 421
+ + E+ + K ++++ S E L E+ LK E EK++ ++ L ++
Sbjct: 388 -LQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGK-EAELEKSSAAHTQATLLLQEKY 445
Query: 422 NSDAQEILIDSLSKKITQVYKVCIGDAED---DGLNPIQKLVKVESRLVELCDLIESIPK 478
+S Q ++ ++ + + + ED + + +K K ++ I +
Sbjct: 446 DSMVQS--LEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATES 503
Query: 479 ENVEAIERMKQKEWRQKFRDEKMKE-------KQRHQQERLKAALEKAVAQPKKKLGRR 530
N E + + + + ++ ++KE K Q +LK E Q + + GR+
Sbjct: 504 SNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFRKQLEDEEGRK 562
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 50.1 bits (118), Expect = 6e-06
Identities = 86/474 (18%), Positives = 193/474 (40%), Gaps = 64/474 (13%)
Query: 125 ALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLR---------ENDQRSVDA 175
+LST+ +K ++ K+ K LQ++ E L E ++ ++A
Sbjct: 1476 SLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEA 1535
Query: 176 LKMAAQETINKLQMTAE-----LKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPK 230
KM Q + + + + E + +A +E +K+EI + E M+ Q
Sbjct: 1536 EKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEME------QAKRN 1589
Query: 231 HWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQ 290
H ++ +L+ + +++++ ++ K+ + E L + R A ++ + S
Sbjct: 1590 HLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSL 1649
Query: 291 GKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMD--------VDLEPALYFKEPEEL 342
K ++ + +L E+ + LL E++ + L +E E
Sbjct: 1650 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIET 1709
Query: 343 LQVLRELEEQNLTLFQYSQDVDENLEEVNKR-EKVIQDKTNSN--IEFLLEQEKMLKANC 399
+ ++ L QN +L + +D +L ++ E+ +Q+ N+ + + M+
Sbjct: 1710 SERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEEL 1769
Query: 400 VREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKL 459
+E++ +A L+ K E I L ++ + ++ + + ++L
Sbjct: 1770 KKEQDTSAHLERMKK----------NMEQTIKDLQHRLDEAEQIALKGGK-------KQL 1812
Query: 460 VKVESRLVELCDLIESIPKENVEAIERMKQKEWRQK-------------FRDEKMKEKQR 506
K+E+R+ EL + +E+ K N E+++ M++ E R K R + + +K +
Sbjct: 1813 QKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQ 1872
Query: 507 HQQERLKAALEKAVAQPKKKLGR-RLVFHSKPPSGNKQQL--PLVNETKTKSQE 557
+ + K E+A Q L + R V H + + + VN+ + KS++
Sbjct: 1873 LKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRD 1926
Score = 44.7 bits (104), Expect = 2e-04
Identities = 80/416 (19%), Positives = 172/416 (41%), Gaps = 42/416 (10%)
Query: 135 KFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAELK 194
K+E D R +L++A+KKL EE + +V+A + ++T ++LQ E++
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAV-----EAVNAKCSSLEKTKHRLQ--NEIE 1426
Query: 195 KASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPK 254
++V+ + A + R + K L + K+ + Q L ++S+ +A + +
Sbjct: 1427 DLMVDVERSNAAAAALDKKQRNFDK---ILAEWKQKYEESQSEL---ESSQKEARSLSTE 1480
Query: 255 ILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESFGS 314
+ + + + E + L E+ S + G +++ + +K AE
Sbjct: 1481 LFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMEL 1540
Query: 315 EDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDEN-LEEVNKR 373
+ +LE + E ++ E + E Q+ E+E + + + N L V+
Sbjct: 1541 QSALE---EAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSL 1597
Query: 374 EKVIQDKTNSNIEFLLEQEKM------LKANCVREEEKAAELQLKSKLFSFGEFNSDAQE 427
+ + +T S E L ++KM ++ AAE Q + K S D Q
Sbjct: 1598 QTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVK--SLQSLLKDTQI 1655
Query: 428 ILIDSLSKKITQVYKVCIGDAEDD----GLNPIQKLVK--------VESRLVELCDLIES 475
L D++ + I + ++ L ++ +V+ E L+E + ++
Sbjct: 1656 QLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQL 1715
Query: 476 IPKENVEAIERMKQKE---WRQKFRDEKMKEKQRHQQERLKAALEKA--VAQPKKK 526
+ +N I + K+ + + + E+ ++ R+ +E+ K A+ A +A+ KK
Sbjct: 1716 LHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 1771
Score = 43.9 bits (102), Expect = 4e-04
Identities = 79/387 (20%), Positives = 152/387 (39%), Gaps = 62/387 (16%)
Query: 153 KLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKTEF 212
+L + + E ++E ++R D +M A+ T K ++ E + ++ ++ +AK E
Sbjct: 907 QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEK 966
Query: 213 -----------LLREYMKYGFFLLQMSPKHWQIQQALKRA----QASKSKANIILPKILA 257
L E + +++ + +Q+A ++A QA + K N L K
Sbjct: 967 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT-LTKAKV 1025
Query: 258 KLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESFGSED- 316
KL + EG LE+ + + E A + + K ++ E K L E +D
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDF 1085
Query: 317 ---SLEFLLDDEMDVDLEPALYFKEPEELLQVL----------------------RELEE 351
+L ++DE + + KE + ++ L RELEE
Sbjct: 1086 ELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEE 1145
Query: 352 QNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQL 411
+ L + +E KRE Q E L+ E A + + AEL
Sbjct: 1146 ISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAEL-- 1203
Query: 412 KSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCD 471
GE + Q + L K+ ++ +K+ + DD + +++++K ++ L ++C
Sbjct: 1204 -------GEQIDNLQRVK-QKLEKEKSE-FKLEL----DDVTSNMEQIIKAKANLEKMCR 1250
Query: 472 LIESIPKENVEAIERMKQKEWRQKFRD 498
+E E+ R K +E ++ D
Sbjct: 1251 TLEDQMNEH-----RSKAEETQRSVND 1272
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 50.1 bits (118), Expect = 6e-06
Identities = 93/459 (20%), Positives = 184/459 (40%), Gaps = 74/459 (16%)
Query: 133 IKKFEKDIAMRERQLKKAEKKLQDDALAFEEF---LRENDQRSVDALKMAAQETINKLQM 189
I++ E++I KAEK+ D + EE L E + ++M + +M
Sbjct: 1121 IEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKM 1180
Query: 190 TAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKAN 249
+L++A+++ +A + + K K+ + ++ + +Q+ ++ + KS+
Sbjct: 1181 RRDLEEATLQHEATAATLRK---------KHADSVAELGEQIDNLQRVKQKLEKEKSEMK 1231
Query: 250 IILPKILAKLSLHSSNKEGILEESGRTAV--LSEDASQGRDSQ----------------- 290
+ + + + + S K G LE+ RT LSE S+ + Q
Sbjct: 1232 MEIDDLASNVETVSKAK-GNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTES 1290
Query: 291 GKPSRSL-----------------TRTPEKKKSNLAESFGSEDSLEFLLDDEM-DVDLEP 332
G+ SR L T+ E+ K L E ++++L L D DL
Sbjct: 1291 GEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLR 1350
Query: 333 ALYFKEPEELLQVLRELEEQNLTLFQ----YSQDVDENLEEVNKREKVIQDKTNSNIEFL 388
Y +E E ++ R L + N + Q Y D + EE+ + +K K ++
Sbjct: 1351 EQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKK----KLAQRLQAA 1406
Query: 389 LEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDA 448
E + + A C E+ LQ + + ++A +D + ++
Sbjct: 1407 EEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKC 1466
Query: 449 EDDG--LNPIQK--------LVKVESRLVELCDLIESIPKENVEAIERMKQ-----KEWR 493
E+ L QK L K+++ E D +E++ +EN + + E
Sbjct: 1467 EETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGG 1526
Query: 494 QKFRD-EKMKEKQRHQQERLKAALEKAVAQPKKKLGRRL 531
++ + EK+K++ ++ L+AALE+A A + + G+ L
Sbjct: 1527 KRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKIL 1565
Score = 47.4 bits (111), Expect = 4e-05
Identities = 84/422 (19%), Positives = 179/422 (42%), Gaps = 43/422 (10%)
Query: 125 ALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETI 184
+L T+ IK ++ + LK+ K LQ + E + E +R + K+ Q
Sbjct: 1482 SLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQ 1541
Query: 185 NKLQMTAELKKASMEVQAVKSEIAKTEFLL--------REYMKYGFFLLQMSPKHWQIQQ 236
K ++ A L++A ++ + +I + + L R+ + + Q+ H +I +
Sbjct: 1542 EKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVE 1601
Query: 237 ALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQG--KPS 294
+++ ++ ++ ++ K+ + E L + R A +E R++QG K +
Sbjct: 1602 SMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA--AEALRNYRNTQGILKDT 1659
Query: 295 RSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKE------PEELLQV--- 345
+ + + +L E + LL E++ +L L E +ELL
Sbjct: 1660 QIHLDDALRSQEDLKEQLAMVERRANLLQAEIE-ELRATLEQTERSRKIAEQELLDASER 1718
Query: 346 LRELEEQNLTLFQYSQDVDENLEEVN-KREKVIQDKTNSN--IEFLLEQEKMLKANCVRE 402
++ L QN +L + ++ ++ ++ + E ++Q+ N+ + + M+ +E
Sbjct: 1719 VQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKE 1778
Query: 403 EEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKV 462
++ +A L+ K E + L ++ + ++ + G IQKL
Sbjct: 1779 QDTSAHLERMKK----------NMEQTVKDLQLRLDEAEQLAL----KGGKKQIQKL--- 1821
Query: 463 ESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQ 522
E+R+ EL +ES K N EA++ +++ E R K E+ R RL+ ++K A+
Sbjct: 1822 EARVRELEGEVESEQKRNAEAVKGLRKHERRVK-ELTYQTEEDRKNILRLQDLVDKLQAK 1880
Query: 523 PK 524
K
Sbjct: 1881 VK 1882
Score = 46.2 bits (108), Expect = 8e-05
Identities = 95/459 (20%), Positives = 178/459 (38%), Gaps = 72/459 (15%)
Query: 126 LSTKRNTIKKFEKDIAMRERQ----LKKAEKK---LQDDALAFEEFLRENDQRSVDALKM 178
L K T+ K + D+ ++ + L AE++ L + E ++E +R+ D ++
Sbjct: 879 LEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEI 938
Query: 179 AAQETINKLQMTAELKKASMEVQAVKSEIAKTEF-----------LLREYMKYGFFLLQM 227
A+ T K ++ E + ++ ++ +AK E L E + ++
Sbjct: 939 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKL 998
Query: 228 SPKHWQIQQA----LKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDA 283
+ + +Q+A L QA + K N L K KL + EG LE+ + + E A
Sbjct: 999 TKEKKALQEAHQQTLDDLQAEEDKVNT-LTKAKIKLEQQVDDLEGSLEQEKKLRMDLERA 1057
Query: 284 SQGRDSQGKPSRSLTRTPEKKKSNLAESFGSED----SLEFLLDDEM------------- 326
+ + K ++ E +K L E ++ +L+ ++DE
Sbjct: 1058 KRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKEL 1117
Query: 327 ---------DVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVI 377
+++ E A K ++ + RELEE + L + +E KRE
Sbjct: 1118 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEF 1177
Query: 378 QDKTNSNIEFLLEQEKMLKANCVREEEKAAEL--------QLKSKLFSFGEFNSDAQEIL 429
Q E L+ E + + AEL ++K KL E ++
Sbjct: 1178 QKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL----EKEKSEMKME 1233
Query: 430 IDSLSKKITQVYKVCIGDAE------DDGLNPIQKLVKVESRLVELCDLIESIPKENVEA 483
ID L+ + V K G+ E +D L+ ++ + + RL+ DL + E+
Sbjct: 1234 IDDLASNVETVSK-AKGNLEKMCRTLEDQLSELKSKEEEQQRLIN--DLTAQRGRLQTES 1290
Query: 484 IERMKQKEWRQKFRDEKMKEKQRHQQ--ERLKAALEKAV 520
E +Q + ++ + + KQ Q E LK LE+ +
Sbjct: 1291 GEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEI 1329
Score = 35.8 bits (81), Expect = 0.11
Identities = 90/462 (19%), Positives = 179/462 (38%), Gaps = 55/462 (11%)
Query: 111 EFINDQRDRFLLEYALSTKRNTIK----KFEKDIAMRERQLKKAEKKLQDDALAFEEFLR 166
++ +Q + L+ ALS + K+E D R +L++A+KKL A EE +
Sbjct: 1352 QYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVE 1411
Query: 167 ENDQR--SVDALKMAAQETINKLQMTAELKKASMEV----------------QAVKSEIA 208
+ + S++ K Q + L + E A+ Q + A
Sbjct: 1412 AVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHA 1471
Query: 209 KTEFLLREYMKYGFFLLQMSPKHWQI---QQALKRAQASKSKANIILPKILAK-----LS 260
+ E +E G L ++ + + + LKR + + L + +A+
Sbjct: 1472 ELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHE 1531
Query: 261 LHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSR---SLTRTPEKKKSNLAESFGSEDS 317
L K+ E+ A L E + +GK R L + + +AE D
Sbjct: 1532 LEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ 1591
Query: 318 LE---FLLDDEMDVDLEPALYFKEPEELLQVLRE--LEEQNLTLFQYSQDVDENLEEVNK 372
L+ + + M L+ + + L+ E L E + L ++ E L
Sbjct: 1592 LKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRN 1651
Query: 373 REKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQ-----LKSKLFSFGEFNSDAQE 427
+ +++D T +++ L ++ LK E +A LQ L++ L A++
Sbjct: 1652 TQGILKD-TQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQ 1710
Query: 428 ILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERM 487
L+D+ S+++ ++ + I K+E+ + ++ +E I +E A E+
Sbjct: 1711 ELLDA-SERVQLLH--------TQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKA 1761
Query: 488 KQKEWRQKFRDEKMKEKQ--RHQQERLKAALEKAVAQPKKKL 527
K+ E++K++Q ER+K +E+ V + +L
Sbjct: 1762 KKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1803
Score = 32.0 bits (71), Expect = 1.6
Identities = 53/273 (19%), Positives = 101/273 (36%), Gaps = 35/273 (12%)
Query: 116 QRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDA 175
+R LL+ + R T+++ E+ + E++L A +++Q L S+
Sbjct: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQ---------LLHTQNTSLIN 1731
Query: 176 LKMAAQETINKLQMTAE--LKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQ 233
K + I+++Q E L++A + K I + E K +
Sbjct: 1732 TKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1791
Query: 234 IQQALKRAQASKSKANIIL----PKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDS 289
++Q +K Q +A + K + KL EG +E + + +A +G
Sbjct: 1792 MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKR---NAEAVKGLRK 1848
Query: 290 QGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLREL 349
+ + LT E+ + N+ L D +D +K E E
Sbjct: 1849 HERRVKELTYQTEEDRKNILR-----------LQDLVDKLQAKVKSYKRQAE------EA 1891
Query: 350 EEQNLTLFQYSQDVDENLEEVNKREKVIQDKTN 382
EEQ+ T + + LEE +R + + + N
Sbjct: 1892 EEQSNTNLAKFRKLQHELEEAEERADIAESQVN 1924
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 50.1 bits (118), Expect = 6e-06
Identities = 93/459 (20%), Positives = 184/459 (40%), Gaps = 74/459 (16%)
Query: 133 IKKFEKDIAMRERQLKKAEKKLQDDALAFEEF---LRENDQRSVDALKMAAQETINKLQM 189
I++ E++I KAEK+ D + EE L E + ++M + +M
Sbjct: 1121 IEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKM 1180
Query: 190 TAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKAN 249
+L++A+++ +A + + K K+ + ++ + +Q+ ++ + KS+
Sbjct: 1181 RRDLEEATLQHEATAATLRK---------KHADSVAELGEQIDNLQRVKQKLEKEKSEMK 1231
Query: 250 IILPKILAKLSLHSSNKEGILEESGRTAV--LSEDASQGRDSQ----------------- 290
+ + + + + S K G LE+ RT LSE S+ + Q
Sbjct: 1232 MEIDDLASNVETVSKAK-GNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTES 1290
Query: 291 GKPSRSL-----------------TRTPEKKKSNLAESFGSEDSLEFLLDDEM-DVDLEP 332
G+ SR L T+ E+ K L E ++++L L D DL
Sbjct: 1291 GEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLR 1350
Query: 333 ALYFKEPEELLQVLRELEEQNLTLFQ----YSQDVDENLEEVNKREKVIQDKTNSNIEFL 388
Y +E E ++ R L + N + Q Y D + EE+ + +K K ++
Sbjct: 1351 EQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKK----KLAQRLQAA 1406
Query: 389 LEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDA 448
E + + A C E+ LQ + + ++A +D + ++
Sbjct: 1407 EEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKC 1466
Query: 449 EDDG--LNPIQK--------LVKVESRLVELCDLIESIPKENVEAIERMKQ-----KEWR 493
E+ L QK L K+++ E D +E++ +EN + + E
Sbjct: 1467 EETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGG 1526
Query: 494 QKFRD-EKMKEKQRHQQERLKAALEKAVAQPKKKLGRRL 531
++ + EK+K++ ++ L+AALE+A A + + G+ L
Sbjct: 1527 KRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKIL 1565
Score = 47.4 bits (111), Expect = 4e-05
Identities = 84/422 (19%), Positives = 179/422 (42%), Gaps = 43/422 (10%)
Query: 125 ALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETI 184
+L T+ IK ++ + LK+ K LQ + E + E +R + K+ Q
Sbjct: 1482 SLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQ 1541
Query: 185 NKLQMTAELKKASMEVQAVKSEIAKTEFLL--------REYMKYGFFLLQMSPKHWQIQQ 236
K ++ A L++A ++ + +I + + L R+ + + Q+ H +I +
Sbjct: 1542 EKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVE 1601
Query: 237 ALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQG--KPS 294
+++ ++ ++ ++ K+ + E L + R A +E R++QG K +
Sbjct: 1602 SMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA--AEALRNYRNTQGILKDT 1659
Query: 295 RSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKE------PEELLQV--- 345
+ + + +L E + LL E++ +L L E +ELL
Sbjct: 1660 QIHLDDALRSQEDLKEQLAMVERRANLLQAEIE-ELRATLEQTERSRKIAEQELLDASER 1718
Query: 346 LRELEEQNLTLFQYSQDVDENLEEVN-KREKVIQDKTNSN--IEFLLEQEKMLKANCVRE 402
++ L QN +L + ++ ++ ++ + E ++Q+ N+ + + M+ +E
Sbjct: 1719 VQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKE 1778
Query: 403 EEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKV 462
++ +A L+ K E + L ++ + ++ + G IQKL
Sbjct: 1779 QDTSAHLERMKK----------NMEQTVKDLQLRLDEAEQLAL----KGGKKQIQKL--- 1821
Query: 463 ESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQ 522
E+R+ EL +ES K N EA++ +++ E R K E+ R RL+ ++K A+
Sbjct: 1822 EARVRELEGEVESEQKRNAEAVKGLRKHERRVK-ELTYQTEEDRKNILRLQDLVDKLQAK 1880
Query: 523 PK 524
K
Sbjct: 1881 VK 1882
Score = 46.2 bits (108), Expect = 8e-05
Identities = 95/459 (20%), Positives = 178/459 (38%), Gaps = 72/459 (15%)
Query: 126 LSTKRNTIKKFEKDIAMRERQ----LKKAEKK---LQDDALAFEEFLRENDQRSVDALKM 178
L K T+ K + D+ ++ + L AE++ L + E ++E +R+ D ++
Sbjct: 879 LEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEI 938
Query: 179 AAQETINKLQMTAELKKASMEVQAVKSEIAKTEF-----------LLREYMKYGFFLLQM 227
A+ T K ++ E + ++ ++ +AK E L E + ++
Sbjct: 939 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKL 998
Query: 228 SPKHWQIQQA----LKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDA 283
+ + +Q+A L QA + K N L K KL + EG LE+ + + E A
Sbjct: 999 TKEKKALQEAHQQTLDDLQAEEDKVNT-LTKAKIKLEQQVDDLEGSLEQEKKLRMDLERA 1057
Query: 284 SQGRDSQGKPSRSLTRTPEKKKSNLAESFGSED----SLEFLLDDEM------------- 326
+ + K ++ E +K L E ++ +L+ ++DE
Sbjct: 1058 KRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKEL 1117
Query: 327 ---------DVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVI 377
+++ E A K ++ + RELEE + L + +E KRE
Sbjct: 1118 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEF 1177
Query: 378 QDKTNSNIEFLLEQEKMLKANCVREEEKAAEL--------QLKSKLFSFGEFNSDAQEIL 429
Q E L+ E + + AEL ++K KL E ++
Sbjct: 1178 QKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL----EKEKSEMKME 1233
Query: 430 IDSLSKKITQVYKVCIGDAE------DDGLNPIQKLVKVESRLVELCDLIESIPKENVEA 483
ID L+ + V K G+ E +D L+ ++ + + RL+ DL + E+
Sbjct: 1234 IDDLASNVETVSK-AKGNLEKMCRTLEDQLSELKSKEEEQQRLIN--DLTAQRGRLQTES 1290
Query: 484 IERMKQKEWRQKFRDEKMKEKQRHQQ--ERLKAALEKAV 520
E +Q + ++ + + KQ Q E LK LE+ +
Sbjct: 1291 GEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEI 1329
Score = 35.8 bits (81), Expect = 0.11
Identities = 90/462 (19%), Positives = 179/462 (38%), Gaps = 55/462 (11%)
Query: 111 EFINDQRDRFLLEYALSTKRNTIK----KFEKDIAMRERQLKKAEKKLQDDALAFEEFLR 166
++ +Q + L+ ALS + K+E D R +L++A+KKL A EE +
Sbjct: 1352 QYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVE 1411
Query: 167 ENDQR--SVDALKMAAQETINKLQMTAELKKASMEV----------------QAVKSEIA 208
+ + S++ K Q + L + E A+ Q + A
Sbjct: 1412 AVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHA 1471
Query: 209 KTEFLLREYMKYGFFLLQMSPKHWQI---QQALKRAQASKSKANIILPKILAK-----LS 260
+ E +E G L ++ + + + LKR + + L + +A+
Sbjct: 1472 ELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHE 1531
Query: 261 LHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSR---SLTRTPEKKKSNLAESFGSEDS 317
L K+ E+ A L E + +GK R L + + +AE D
Sbjct: 1532 LEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ 1591
Query: 318 LE---FLLDDEMDVDLEPALYFKEPEELLQVLRE--LEEQNLTLFQYSQDVDENLEEVNK 372
L+ + + M L+ + + L+ E L E + L ++ E L
Sbjct: 1592 LKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRN 1651
Query: 373 REKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQ-----LKSKLFSFGEFNSDAQE 427
+ +++D T +++ L ++ LK E +A LQ L++ L A++
Sbjct: 1652 TQGILKD-TQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQ 1710
Query: 428 ILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERM 487
L+D+ S+++ ++ + I K+E+ + ++ +E I +E A E+
Sbjct: 1711 ELLDA-SERVQLLH--------TQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKA 1761
Query: 488 KQKEWRQKFRDEKMKEKQ--RHQQERLKAALEKAVAQPKKKL 527
K+ E++K++Q ER+K +E+ V + +L
Sbjct: 1762 KKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1803
Score = 32.0 bits (71), Expect = 1.6
Identities = 53/273 (19%), Positives = 101/273 (36%), Gaps = 35/273 (12%)
Query: 116 QRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDA 175
+R LL+ + R T+++ E+ + E++L A +++Q L S+
Sbjct: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQ---------LLHTQNTSLIN 1731
Query: 176 LKMAAQETINKLQMTAE--LKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQ 233
K + I+++Q E L++A + K I + E K +
Sbjct: 1732 TKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1791
Query: 234 IQQALKRAQASKSKANIIL----PKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDS 289
++Q +K Q +A + K + KL EG +E + + +A +G
Sbjct: 1792 MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKR---NAEAVKGLRK 1848
Query: 290 QGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLREL 349
+ + LT E+ + N+ L D +D +K E E
Sbjct: 1849 HERRVKELTYQTEEDRKNILR-----------LQDLVDKLQAKVKSYKRQAE------EA 1891
Query: 350 EEQNLTLFQYSQDVDENLEEVNKREKVIQDKTN 382
EEQ+ T + + LEE +R + + + N
Sbjct: 1892 EEQSNTNLAKFRKLQHELEEAEERADIAESQVN 1924
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 49.7 bits (117), Expect = 7e-06
Identities = 91/496 (18%), Positives = 199/496 (40%), Gaps = 63/496 (12%)
Query: 98 RLIEGSDTKRTVHEFINDQRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDD 157
R +E + +R E Q+ R E L K+ ++ E+ RE+Q E++ Q +
Sbjct: 279 RKLERQELRRERQEE-EQQQQRLRREQQLRRKQEEERR-EQQEERREQQ----ERREQQE 332
Query: 158 ALAFEEFLRENDQRSVDALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREY 217
++ RE ++R L+ +E + Q+ E ++ E Q + + + E LR
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE 392
Query: 218 MKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTA 277
+ + + +Q L+R Q + + + + E E+ R
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQL-------RREQEEERHEQKHEQERREQ 445
Query: 278 VLSEDASQGRDSQGKPSRSLTRTPEKKKSNLA-----------------ESFGSEDSLEF 320
L + + RD + + E++K L E ++ E
Sbjct: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQ 505
Query: 321 LLDDEMDVDLEPALYFKEPEELLQ--------VLRELEEQNLTLFQYSQDVDENLEEVNK 372
L E + E L +E EE LQ + RE EE+ L + ++ ++ LE+ +
Sbjct: 506 QLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK--REEEKRLEQERR 563
Query: 373 REKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDS 432
+++ +++ + L +E+ + RE+E+ E +LK + ++
Sbjct: 564 EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREE--------------VER 609
Query: 433 LSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKEN-------VEAIE 485
L ++ + ++ + E++ + K + E R + + +E E +E
Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLE 669
Query: 486 RMKQKEWRQKFRDEKMKEKQRHQ-QERLKAALEKAVAQPKKKL-GRRLVFHSKPPSGNKQ 543
+ ++E ++ R++++ E+++ Q +ER+K+ + K Q + + R+ +S+P Q
Sbjct: 670 QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQ 729
Query: 544 QLPLVNETKTKSQEEE 559
+ E K + +E E
Sbjct: 730 RRRQEQEEKRRRRESE 745
Score = 40.4 bits (93), Expect = 0.004
Identities = 70/397 (17%), Positives = 160/397 (40%), Gaps = 42/397 (10%)
Query: 137 EKDIAMRERQLKKAEKKLQDDA-------LAFEEFLRENDQRSVDALKMAAQETINKLQM 189
EK+ RE L+K E+KLQ++ EE LR+ +++ + + ++ +L+
Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302
Query: 190 TAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKAN 249
+L++ E + + E + + RE + + +Q L+R Q + +
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEE------------RREQQLRREQEERREQQ 350
Query: 250 IILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLA 309
+ + + ++ EE R L + R+ Q + + L R + ++
Sbjct: 351 LRREQEEERREQQLRREQ---EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 407
Query: 310 ESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEE 369
E L E + E L ++ EE + E E + L + ++ + L+
Sbjct: 408 RR-------EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKR 460
Query: 370 VNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEIL 429
+ E+ Q++ ++ E+E+ + + EEE+ + + + + + Q +
Sbjct: 461 EEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLK 520
Query: 430 IDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQ 489
+++ Q + + Q + E R +L E E +R+K+
Sbjct: 521 RQEEEERLQQRLR-----------SEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
Query: 490 KEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKK 526
++ ++ RD+ +K ++ +Q+RLK E+ + Q K+
Sbjct: 570 EQ--EERRDQLLKREEERRQQRLKREQEERLEQRLKR 604
Score = 40.0 bits (92), Expect = 0.006
Identities = 89/467 (19%), Positives = 180/467 (38%), Gaps = 76/467 (16%)
Query: 113 INDQRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRS 172
+ +QR+R L + E++ R RQ ++ EK+LQ FL E +Q
Sbjct: 790 LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQ--------FLEEEEQLQ 841
Query: 173 VDALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHW 232
QE + LQ E +++ + R K+ W
Sbjct: 842 RRERAQQLQEEEDGLQEDQERRRSQEQ---------------RRDQKW----------RW 876
Query: 233 QIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDS--- 289
Q+++ KR + + + ++ + L +E + E E Q R+
Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936
Query: 290 QGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRE- 348
Q + + L EK++ E ++ D ++ E L +EPE+ + RE
Sbjct: 937 QQEEEQLLREEREKRRR-------QERERQYRKDKKLQ-QKEEQLLGEEPEKRRRQEREK 988
Query: 349 --LEEQNLTLFQYSQDVDENL--EEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEE 404
EE+ L Q +E L EE KR + ++ + L ++E+ L +REE
Sbjct: 989 KYREEEEL------QQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQL----LREER 1038
Query: 405 KAAELQLKSKLFSFGEFNSDAQEILIDS-----LSKKITQVYKVCIGDAEDDGLNPIQKL 459
+ LQ + + + E +E L+ +++ + Y+ E++ ++L
Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR-----KEEELQQEEEQL 1093
Query: 460 VKVE------SRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLK 513
++ E C E + +E + + ++K RQ+ + + +E++ QQE +
Sbjct: 1094 LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQEL-ERQYREEEEVQQEEEQ 1152
Query: 514 AALEKAVAQPKKKLGRRLVFHSKPPSGNKQQLPLVNETKTKSQEEEY 560
E+ + +++L R+ + +Q L E + + +E +Y
Sbjct: 1153 LLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQY 1199
Score = 39.3 bits (90), Expect = 0.010
Identities = 85/446 (19%), Positives = 183/446 (41%), Gaps = 47/446 (10%)
Query: 116 QRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAE-KKLQDDALAFEEFLRENDQRSVD 174
+RDR E +R ++ E+ E+QL++ +K +++ E+ L+E +++ +
Sbjct: 1427 ERDRKFREEEQQVRR---QERERKFLEEEQQLRQERHRKFREE----EQLLQEREEQQLH 1479
Query: 175 ALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQI 234
+ + + Q+ + + Q ++S+ + +FL E + Q K Q
Sbjct: 1480 RQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR---QQRQRKFLQE 1536
Query: 235 QQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPS 294
+Q L+R + + + K + L +E L Q RD + +
Sbjct: 1537 EQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR------------QERDRKFRLE 1584
Query: 295 RSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNL 354
R E+++ F ++ + + + E F+E E+LLQ E EEQ L
Sbjct: 1585 EQKVRRQEQERK-----FMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ---EREEQQL 1636
Query: 355 TLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSK 414
+ + E ++ ++E+ Q + + + +F E+E++L+ EE+ Q + +
Sbjct: 1637 HRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFR-EEEQLLQEG----EEQQLRRQERDR 1691
Query: 415 LFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKL-VKVESRLVELCDLI 473
+F + Q++ +K Q + + ++L + E + +
Sbjct: 1692 -----KFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERY 1746
Query: 474 ESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRLVF 533
I +E ER +Q+ RQ+ RD K +E+++ +QER + L + K + +L
Sbjct: 1747 RKILEEEQLRPEREEQQLRRQE-RDRKFREEEQLRQEREEQQLRSQESDRKFREEEQL-- 1803
Query: 534 HSKPPSGNKQQLPLVNETKTKSQEEE 559
+ +Q P + K + +EE+
Sbjct: 1804 --RQEREEQQLRPQQRDGKYRWEEEQ 1827
Score = 38.1 bits (87), Expect = 0.022
Identities = 88/444 (19%), Positives = 176/444 (39%), Gaps = 47/444 (10%)
Query: 106 KRTVHEFINDQRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAE---KKLQDDALAFE 162
+R + +RDR LE + +++ E+D RE++L+ E K L+++
Sbjct: 1472 EREEQQLHRQERDRKFLE-----EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR 1526
Query: 163 E-----FLRENDQ-RSVDALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKTEFLLRE 216
+ FL+E Q R + + Q+ K + +L++ E Q + E + L +
Sbjct: 1527 QQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQ 1586
Query: 217 YMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRT 276
++ + K + +Q L+R + + K L +E L R
Sbjct: 1587 KVRRQ----EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERD 1642
Query: 277 AVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYF 336
E+ Q R + + R + ++ G E L D F
Sbjct: 1643 RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRK---------F 1693
Query: 337 KEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQE---K 393
+E E Q LR E + L + Q + LE + E+ ++ +T E L QE K
Sbjct: 1694 REEE---QQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ--EQLRRQERYRK 1748
Query: 394 MLKANCVREEEKAAELQLKSKLFSFGEFNS-----DAQEILIDSLSKKITQVYKVCIGDA 448
+L+ +R E + +L+ + + F E + Q++ +K + ++ +
Sbjct: 1749 ILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLR-QER 1807
Query: 449 EDDGLNPIQKLVKV--ESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMK---- 502
E+ L P Q+ K E ++L + + + +E +Q ++K R E+ +
Sbjct: 1808 EEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQE 1867
Query: 503 EKQRHQQERLKAALEKAVAQPKKK 526
E+Q+ +QER + E+ + + +K+
Sbjct: 1868 EEQKRRQERERKLREEHIRRQQKE 1891
Score = 37.4 bits (85), Expect = 0.037
Identities = 86/451 (19%), Positives = 174/451 (38%), Gaps = 54/451 (11%)
Query: 115 DQRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVD 174
+ RDR L E +R ++ E+++A E Q +K E+ Q D +E L Q +
Sbjct: 123 EPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQE 182
Query: 175 ALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQI 234
+ A+E + K E + ++ + E L E + G Q + Q
Sbjct: 183 REERRAEE-----EQLQSCKGHETEEFPDEEQLRRRELL--ELRRKGREEKQQQRRERQD 235
Query: 235 QQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPS 294
+ + + K +L K KL EE R L E+ Q R + +
Sbjct: 236 RVFQEEEEKEWRKRETVLRKEEEKLQE---------EEPQRQRELQEEEEQLRKLERQEL 286
Query: 295 RSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNL 354
R + E+++ L E L ++E E +E E + RE + +
Sbjct: 287 RRERQEEEQQQQRLRR----EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342
Query: 355 TLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSK 414
+ Q + EE + +++ +++ E L +E+ L+ RE++ E QL+ +
Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR----REQQLRREQQLRRE 398
Query: 415 LFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIE 474
Q++ + ++ Q+ + Q+L + + E +
Sbjct: 399 -----------QQLRREQQLRREQQLRRE-------------QQLRREQQLRREQEEERH 434
Query: 475 SIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRLVFH 534
E +R+K+++ ++ ++ +E +RH+QER K L++ + +++ +L
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEE 494
Query: 535 SKPPSGNKQQLPL------VNETKTKSQEEE 559
+ +++ L E + K QEEE
Sbjct: 495 ERREQQERREQQLRREQEERREQRLKRQEEE 525
Score = 36.2 bits (82), Expect = 0.082
Identities = 81/404 (20%), Positives = 171/404 (42%), Gaps = 45/404 (11%)
Query: 143 RERQLKKAEKKLQDDALAFEEFLRENDQ-RSVDALKMAAQETINKLQMTAELKKASMEVQ 201
RE+QL++ ++ ++ L E+ LR Q R L+ +E ++ + E ++ ++
Sbjct: 391 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK-- 448
Query: 202 AVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQ--QALKRAQASKSKANIILPKILAKL 259
+ + + ++L RE + + +H Q + Q LKR Q + +
Sbjct: 449 --REQEERRDWLKRE---------EETERHEQERRKQQLKRDQEEERRERW--------- 488
Query: 260 SLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLE 319
L +E ++ R L + + R+ + K R ++ +S E+ E
Sbjct: 489 -LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547
Query: 320 FLLDDEMDVDLEPA-----LYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKRE 374
LL E + LE L ++ E Q+L+ EE+ + Q+ E LE+ KRE
Sbjct: 548 QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE--ERLEQRLKRE 605
Query: 375 KVIQDKTNSNIEFLLEQEK--------MLKANCVREEEKAAELQLKSKLFSFGEFNSDAQ 426
+V + + E L++E+ +LK+ E+E+ + QL+ + E +
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQLLKSE---EQEERRQQQLRREQQERREQRLKRE 662
Query: 427 EILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIER 486
E + L +++ + ++ + E Q +++SR+ + +ES +
Sbjct: 663 EEE-ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYS 721
Query: 487 MKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRR 530
+K+ Q+ R E+ ++++R + E E+A Q +++ RR
Sbjct: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR 765
Score = 32.0 bits (71), Expect = 1.6
Identities = 65/323 (20%), Positives = 133/323 (41%), Gaps = 37/323 (11%)
Query: 226 QMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQ 285
Q +H+ ++ L+R + ++K + +L ++ +E+ R E Q
Sbjct: 1287 QQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQ 1346
Query: 286 GRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELL-- 343
R+ Q L R +K E E +FL +++ E F + E+ L
Sbjct: 1347 EREEQ-----PLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRC 1401
Query: 344 ----QVLRE-------LEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQE 392
Q LR+ EEQ L+ + + E ++V ++E+ ++ E L QE
Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQER---ERKFLEEEQQLRQE 1458
Query: 393 KMLKANCVREEEKAAELQLKSKLFSFG---EFNSDAQEILIDSLSKKITQVYKVCIGDAE 449
+ K REEE+ + + + +L +F + Q++ +K + E
Sbjct: 1459 RHRK---FREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE--------QE 1507
Query: 450 DDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQ 509
P +K ++ E +L + + +E + + R ++ + R++ RD K +E+++ +Q
Sbjct: 1508 LRSQEPERKFLEEEQQLHRQQRQRKFLQEE--QQLRRQERGQQRRQDRDRKFREEEQLRQ 1565
Query: 510 ERLKAALEKAVAQPKKKLGRRLV 532
ER + L + K +L + V
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKV 1588
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,366,238
Number of Sequences: 37866
Number of extensions: 872539
Number of successful extensions: 6790
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 473
Number of HSP's that attempted gapping in prelim test: 4893
Number of HSP's gapped (non-prelim): 1576
length of query: 563
length of database: 18,247,518
effective HSP length: 107
effective length of query: 456
effective length of database: 14,195,856
effective search space: 6473310336
effective search space used: 6473310336
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.