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Search of human proteins with 226443028
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens]
(416 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens] 822 0.0
gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens] 798 0.0
gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens] 798 0.0
gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens] 718 0.0
gi|226443017 GRAM domain containing 3 isoform 3 [Homo sapiens] 647 0.0
gi|60593095 GRAM domain containing 2 [Homo sapiens] 140 2e-33
gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens] 106 4e-23
gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens] 105 1e-22
gi|144227752 GRAM domain containing 1B [Homo sapiens] 100 3e-21
gi|187936935 GRAM domain containing 1C [Homo sapiens] 97 2e-20
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho... 62 7e-10
gi|156231067 TBC1 domain family, member 8 [Homo sapiens] 54 2e-07
gi|45597177 TBC1 domain family, member 9B (with GRAM domain) iso... 49 1e-05
gi|45597175 TBC1 domain family, member 9B (with GRAM domain) iso... 49 1e-05
gi|38570103 TBC1 domain family, member 8B (with GRAM domain) iso... 44 2e-04
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso... 44 2e-04
gi|67763814 death-inducing-protein [Homo sapiens] 38 0.019
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 33 0.37
gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens] 33 0.48
gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens] 33 0.62
gi|168229156 NFKB activating protein [Homo sapiens] 32 0.81
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 32 1.1
gi|39995071 exonuclease 1 isoform b [Homo sapiens] 32 1.4
gi|39995069 exonuclease 1 isoform a [Homo sapiens] 32 1.4
gi|18491016 exonuclease 1 isoform b [Homo sapiens] 32 1.4
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 32 1.4
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 32 1.4
gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens] 32 1.4
gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens] 32 1.4
gi|110349719 titin isoform N2-A [Homo sapiens] 31 1.8
>gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens]
Length = 416
Score = 822 bits (2124), Expect = 0.0
Identities = 416/416 (100%), Positives = 416/416 (100%)
Query: 1 MSKVKRFPFFFSSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGA 60
MSKVKRFPFFFSSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGA
Sbjct: 1 MSKVKRFPFFFSSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGA 60
Query: 61 SLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKE 120
SLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKE
Sbjct: 61 SLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKE 120
Query: 121 ILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYI 180
ILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYI
Sbjct: 121 ILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYI 180
Query: 181 FVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDG 240
FVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDG
Sbjct: 181 FVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDG 240
Query: 241 VVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGK 300
VVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGK
Sbjct: 241 VVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGK 300
Query: 301 AKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLG 360
AKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLG
Sbjct: 301 AKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLG 360
Query: 361 LLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD 416
LLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD
Sbjct: 361 LLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD 416
>gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens]
Length = 447
Score = 798 bits (2061), Expect = 0.0
Identities = 404/404 (100%), Positives = 404/404 (100%)
Query: 13 SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE 72
SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE
Sbjct: 44 SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE 103
Query: 73 SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN 132
SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN
Sbjct: 104 SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN 163
Query: 133 WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK 192
WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK
Sbjct: 164 WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK 223
Query: 193 LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY 252
LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY
Sbjct: 224 LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY 283
Query: 253 SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET 312
SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET
Sbjct: 284 SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET 343
Query: 313 VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE 372
VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE
Sbjct: 344 VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE 403
Query: 373 QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD 416
QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD
Sbjct: 404 QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD 447
>gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens]
Length = 432
Score = 798 bits (2061), Expect = 0.0
Identities = 404/404 (100%), Positives = 404/404 (100%)
Query: 13 SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE 72
SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE
Sbjct: 29 SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE 88
Query: 73 SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN 132
SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN
Sbjct: 89 SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN 148
Query: 133 WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK 192
WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK
Sbjct: 149 WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK 208
Query: 193 LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY 252
LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY
Sbjct: 209 LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY 268
Query: 253 SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET 312
SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET
Sbjct: 269 SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET 328
Query: 313 VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE 372
VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE
Sbjct: 329 VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE 388
Query: 373 QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD 416
QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD
Sbjct: 389 QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD 432
>gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens]
Length = 440
Score = 718 bits (1854), Expect = 0.0
Identities = 364/364 (100%), Positives = 364/364 (100%)
Query: 53 SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS 112
SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS
Sbjct: 77 SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS 136
Query: 113 FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII 172
FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII
Sbjct: 137 FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII 196
Query: 173 ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN 232
ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN
Sbjct: 197 ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN 256
Query: 233 DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH 292
DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH
Sbjct: 257 DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH 316
Query: 293 VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI 352
VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI
Sbjct: 317 VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI 376
Query: 353 NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL 412
NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL
Sbjct: 377 NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL 436
Query: 413 ENGD 416
ENGD
Sbjct: 437 ENGD 440
>gi|226443017 GRAM domain containing 3 isoform 3 [Homo sapiens]
Length = 328
Score = 647 bits (1669), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 90 YKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISI 149
YKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISI
Sbjct: 2 YKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISI 61
Query: 150 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNS 209
PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNS
Sbjct: 62 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNS 121
Query: 210 PNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH 269
PNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH
Sbjct: 122 PNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH 181
Query: 270 ATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHH 329
ATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHH
Sbjct: 182 ATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHH 241
Query: 330 ILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEV 389
ILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEV
Sbjct: 242 ILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEV 301
Query: 390 LCQELTANIVKLEKIQNNLQKLLENGD 416
LCQELTANIVKLEKIQNNLQKLLENGD
Sbjct: 302 LCQELTANIVKLEKIQNNLQKLLENGD 328
>gi|60593095 GRAM domain containing 2 [Homo sapiens]
Length = 354
Score = 140 bits (354), Expect = 2e-33
Identities = 99/281 (35%), Positives = 140/281 (49%), Gaps = 20/281 (7%)
Query: 91 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIP 150
K N +HKLF VP EE + + +CALQ++ L QG+L++S NW+CFH+ +FGKD K+ IP
Sbjct: 69 KYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKVVIP 128
Query: 151 AFSVTLIKKTKTALLVPNALIIATVT-DRYIFVSLLSRDSTYKLLKSVCGHLENTSVGN- 208
SV +IKK K A L+PN L I T T +YIFVSLLSRDS Y LL+ VC HL+ +S +
Sbjct: 129 VVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSKKSL 188
Query: 209 -----SPNPSS-----AENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQ 258
S P S E +R PSS L D + D +
Sbjct: 189 SVREFSGEPESLEVLIPEMKWRKVCPSSRSLSLPDNIP----CIPPSSVDSTDSFFPSRK 244
Query: 259 TPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHK 318
P SE SR A+E+ P N P K L E +
Sbjct: 245 PPMSEKSRAQVASENGGRWAWPMPGWGPACPKKMPNCSPTAKNAVYEEDELEEEPRSTGE 304
Query: 319 VKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQL 359
++ + +L + +++C L++S+ Y+ +RI+ LE+QL
Sbjct: 305 LRLWD----YRLLKVFFVLICFLVMSSSYLAFRISRLEQQL 341
>gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens]
Length = 724
Score = 106 bits (264), Expect = 4e-23
Identities = 60/164 (36%), Positives = 91/164 (55%), Gaps = 5/164 (3%)
Query: 36 PSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSS-----SSSQY 90
PS P+ ++ S SS + + + S+N + +K S S +
Sbjct: 28 PSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKKMQSWYSMLSPTYK 87
Query: 91 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIP 150
+ N F KLF +P E L ++CALQ+EIL QG+L++SENWICF+S +F +T ISI
Sbjct: 88 QRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQ 147
Query: 151 AFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 194
VT +KK KTA L+PNA+ I T ++++ F S +RD + L+
Sbjct: 148 LKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLI 191
>gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens]
Length = 713
Score = 105 bits (261), Expect = 1e-22
Identities = 59/159 (37%), Positives = 89/159 (55%), Gaps = 2/159 (1%)
Query: 36 PSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMH 95
PS P+ ++ S SS + + + S+N + + S + Q N
Sbjct: 28 PSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKMLSPTYKQ--RNED 85
Query: 96 FHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVT 155
F KLF +P E L ++CALQ+EIL QG+L++SENWICF+S +F +T ISI VT
Sbjct: 86 FRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVT 145
Query: 156 LIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 194
+KK KTA L+PNA+ I T ++++ F S +RD + L+
Sbjct: 146 CLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLI 184
>gi|144227752 GRAM domain containing 1B [Homo sapiens]
Length = 738
Score = 100 bits (248), Expect = 3e-21
Identities = 59/173 (34%), Positives = 95/173 (54%), Gaps = 13/173 (7%)
Query: 31 AQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKN---DCKTESKNDPKTERKKSSS- 86
++SPTP + D ++ S S D + ++ C ++S KKS S
Sbjct: 28 SRSPTPQ----NQDGDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSGRSGGKNSKKSQSW 83
Query: 87 ----SSQYKA-NMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVF 141
S YK N F KLF +P E L ++CALQ++IL QG+L++SENWICF+S +F
Sbjct: 84 YNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIF 143
Query: 142 GKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 194
+T +++ + + K KTA L+PNA+ + T ++++ F S +RD TY ++
Sbjct: 144 RWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMMM 196
>gi|187936935 GRAM domain containing 1C [Homo sapiens]
Length = 662
Score = 97.4 bits (241), Expect = 2e-20
Identities = 47/107 (43%), Positives = 71/107 (66%), Gaps = 1/107 (0%)
Query: 86 SSSQYK-ANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKD 144
SSS YK N + + F +P E L + CALQ++IL QG+L++SENW+CF+S +F +
Sbjct: 60 SSSTYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWE 119
Query: 145 TKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTY 191
T ISI ++T + K KTA L+PNA+ I T ++++ F S +RD +Y
Sbjct: 120 TTISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSY 166
>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
sapiens]
Length = 1266
Score = 62.4 bits (150), Expect = 7e-10
Identities = 38/125 (30%), Positives = 73/125 (58%), Gaps = 10/125 (8%)
Query: 74 KNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQK-EILYQGKLFVSEN 132
K D TE+ K +A + FH+LF +P EE L ++C+ K ++ QG +++S N
Sbjct: 133 KEDDDTEKFK-------EAIVKFHRLF-GMPEEEKLVNYYSCSYWKGKVPRQGWMYLSIN 184
Query: 133 WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK 192
+CF+S + G++ K+ I +T ++K T LL+P+ + ++T + + F L+ + T+K
Sbjct: 185 HLCFYSFLMGREAKLVIRWVDITQLEKNAT-LLLPDVIKVSTRSSEHFFSVFLNINETFK 243
Query: 193 LLKSV 197
L++ +
Sbjct: 244 LMEQL 248
Score = 48.5 bits (114), Expect = 1e-05
Identities = 51/244 (20%), Positives = 107/244 (43%), Gaps = 33/244 (13%)
Query: 46 KKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPT 105
+++ ++ + D D++ K + K+ K K ++ K+ + + +P
Sbjct: 246 EQLANIAMRQLLDNEGFEQDRSLPKLKRKSPKKVSALKRDLDARAKSERY--RALFRLPK 303
Query: 106 EEPLKQSFTCALQ---KEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKT 162
+E L C L ++ G++FVS N+ICF SK + I IP VT+++K +
Sbjct: 304 DEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENLCSLI-IPLREVTIVEKADS 362
Query: 163 ALLVPNALIIATVTD-RYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRA 221
+ ++P+ L I+T ++F +L RD L++ + L+ T+ + +
Sbjct: 363 SSVLPSPLSISTRNRMTFLFANLKDRDF---LVQRISDFLQQTT-----------SKIYS 408
Query: 222 DRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH------ATESQT 275
D+ +F ++ D V R + S S + +++ R F+ T +QT
Sbjct: 409 DK------EFAGSYNSSDDEVYSRPSSLVSSSPQRSTSSDADGERQFNLNGNSVPTATQT 462
Query: 276 VLNV 279
++ +
Sbjct: 463 LMTM 466
>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
Length = 1140
Score = 54.3 bits (129), Expect = 2e-07
Identities = 48/196 (24%), Positives = 91/196 (46%), Gaps = 23/196 (11%)
Query: 91 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILY---QGKLFVSENWICFHSKVFGKDTKI 147
+A F + F +P +E L C+L G++F S+++ICF S+ G KI
Sbjct: 281 RAQNEFFRAFFRLPRKEKLHAVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGC-CKI 339
Query: 148 SIPAFSVTLIKKTKTALLVPNALIIATVTD-RYIFVSLLSRDSTYKLLKSVCGHLENTSV 206
+P V I+K + L+P+ +I++ + + F+ L RDS L++++ L+
Sbjct: 340 ILPLREVVSIEKMEDTSLLPHPIIVSIRSKVAFQFIELRDRDS---LVEALLARLKQVHA 396
Query: 207 GNSPN-PSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDME--------------G 251
+ + +SA++ + S + + F DL+ + Q ++ E
Sbjct: 397 NHPVHYDTSADDDMASLVFHSTSMCSDHRFGDLEMMSSQNSEESEKEKSPLMHPDALVTA 456
Query: 252 YSSSGSQTPESENSRD 267
+ SGSQ+P+S SR+
Sbjct: 457 FQQSGSQSPDSRMSRE 472
Score = 44.7 bits (104), Expect = 2e-04
Identities = 32/139 (23%), Positives = 66/139 (47%), Gaps = 12/139 (8%)
Query: 60 ASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQK 119
A +A + + E + +P+ R+ + +++A +F P E L ++C K
Sbjct: 120 ALIAEETSSRLAEQEEEPEKFRE---ALVKFEARFNF-------PEAEKLVTYYSCCCWK 169
Query: 120 -EILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDR 178
+ QG L++S N +CF+S GK+ K+ +P + +++T L + + I T
Sbjct: 170 GRVPRQGWLYLSINHLCFYSFFLGKELKLVVPWVDIQKLERTSNVFLT-DTIRITTQNKE 228
Query: 179 YIFVSLLSRDSTYKLLKSV 197
F L+ D +K+++ +
Sbjct: 229 RDFSMFLNLDEVFKVMEQL 247
>gi|45597177 TBC1 domain family, member 9B (with GRAM domain)
isoform b [Homo sapiens]
Length = 1233
Score = 48.5 bits (114), Expect = 1e-05
Identities = 36/155 (23%), Positives = 73/155 (47%), Gaps = 13/155 (8%)
Query: 44 DQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSV 103
D ++ I+ + K G +A + + + + DP ++ A + K F +
Sbjct: 102 DSEEDITTFVKGKIHGI-IAEENKNLQPQGDEDPGKFKE---------AELKMRKQF-GM 150
Query: 104 PTEEPLKQSFTCALQK-EILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKT 162
P E L ++C+ K + QG L+++ N +CF+S + GK+ + + +T ++K T
Sbjct: 151 PEGEKLVNYYSCSYWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSLVVQWVDITRLEKNAT 210
Query: 163 ALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSV 197
LL P ++ + T F L+ T+KL++ +
Sbjct: 211 -LLFPESIRVDTRDQELFFSMFLNIGETFKLMEQL 244
Score = 46.6 bits (109), Expect = 4e-05
Identities = 50/210 (23%), Positives = 94/210 (44%), Gaps = 33/210 (15%)
Query: 91 KANMHFHKLFLSVPTEEPLKQSFTCALQ---KEILYQGKLFVSENWICFHSKVFGKDTKI 147
+A ++ +P +E L +C L ++ G++F+S N+ICF SK +
Sbjct: 284 RAKNECYRATFRLPRDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICFASKE-EDACHL 342
Query: 148 SIPAFSVTLIKKTKTALLVPNALIIATVTD-RYIFVSLLSRDSTYKLLKSVCGHLENT-- 204
IP VT+++K ++ ++P+ L I+T + ++F +L RD L++ + L+ T
Sbjct: 343 IIPLREVTIVEKADSSSVLPSPLSISTKSKMTFLFANLKDRDF---LVQRISDFLQKTPS 399
Query: 205 ----SVGN----------SPNPSSAENSFRADRPSSLPLDFNDEF------SDLDGVVQ- 243
S+G+ +P+ E S + P+S PL F + G+++
Sbjct: 400 KQPGSIGSRKASVVDPSTESSPAPQEGSEQPASPAS-PLSSRQSFCAQEAPTASQGLLKL 458
Query: 244 -QRRQDMEGYSSSGSQTPESENSRDFHATE 272
Q+ ME + G++ E S H E
Sbjct: 459 FQKNSPMEDLGAKGAKEKMKEESWHIHFFE 488
>gi|45597175 TBC1 domain family, member 9B (with GRAM domain)
isoform a [Homo sapiens]
Length = 1250
Score = 48.5 bits (114), Expect = 1e-05
Identities = 36/155 (23%), Positives = 73/155 (47%), Gaps = 13/155 (8%)
Query: 44 DQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSV 103
D ++ I+ + K G +A + + + + DP ++ A + K F +
Sbjct: 102 DSEEDITTFVKGKIHGI-IAEENKNLQPQGDEDPGKFKE---------AELKMRKQF-GM 150
Query: 104 PTEEPLKQSFTCALQK-EILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKT 162
P E L ++C+ K + QG L+++ N +CF+S + GK+ + + +T ++K T
Sbjct: 151 PEGEKLVNYYSCSYWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSLVVQWVDITRLEKNAT 210
Query: 163 ALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSV 197
LL P ++ + T F L+ T+KL++ +
Sbjct: 211 -LLFPESIRVDTRDQELFFSMFLNIGETFKLMEQL 244
Score = 46.6 bits (109), Expect = 4e-05
Identities = 50/210 (23%), Positives = 94/210 (44%), Gaps = 33/210 (15%)
Query: 91 KANMHFHKLFLSVPTEEPLKQSFTCALQ---KEILYQGKLFVSENWICFHSKVFGKDTKI 147
+A ++ +P +E L +C L ++ G++F+S N+ICF SK +
Sbjct: 284 RAKNECYRATFRLPRDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICFASKE-EDACHL 342
Query: 148 SIPAFSVTLIKKTKTALLVPNALIIATVTD-RYIFVSLLSRDSTYKLLKSVCGHLENT-- 204
IP VT+++K ++ ++P+ L I+T + ++F +L RD L++ + L+ T
Sbjct: 343 IIPLREVTIVEKADSSSVLPSPLSISTKSKMTFLFANLKDRDF---LVQRISDFLQKTPS 399
Query: 205 ----SVGN----------SPNPSSAENSFRADRPSSLPLDFNDEF------SDLDGVVQ- 243
S+G+ +P+ E S + P+S PL F + G+++
Sbjct: 400 KQPGSIGSRKASVVDPSTESSPAPQEGSEQPASPAS-PLSSRQSFCAQEAPTASQGLLKL 458
Query: 244 -QRRQDMEGYSSSGSQTPESENSRDFHATE 272
Q+ ME + G++ E S H E
Sbjct: 459 FQKNSPMEDLGAKGAKEKMKEESWHIHFFE 488
>gi|38570103 TBC1 domain family, member 8B (with GRAM domain)
isoform b [Homo sapiens]
Length = 632
Score = 44.3 bits (103), Expect = 2e-04
Identities = 28/111 (25%), Positives = 59/111 (53%), Gaps = 3/111 (2%)
Query: 91 KANMHFHKLFLSVPTEEPLKQSFTCALQK-EILYQGKLFVSENWICFHSKVFGKDTKISI 149
+A + F K F +P +E L ++C+ K + QG L++S N++ F+S + G + K+ I
Sbjct: 142 EALLKFEKCF-GLPEKEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLII 200
Query: 150 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGH 200
V+ ++KT +L ++ + + + + F L + TY L++ + +
Sbjct: 201 SWDEVSKLEKTSNVILT-ESIHVCSQGENHYFSMFLHINQTYLLMEQLANY 250
Score = 35.4 bits (80), Expect = 0.096
Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)
Query: 91 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILY---QGKLFVSENWICFHSKVFGKDTKI 147
+A+ F +P E LK+ C L + GK+ +SEN+ICF S+ G +
Sbjct: 281 RAHSEQFNAFFRLPKGESLKEVHECFLWVPFSHFNTHGKMCISENYICFASQ-DGNQCSV 339
Query: 148 SIPAFSVTLIKKT 160
IP V I KT
Sbjct: 340 IIPLREVLAIDKT 352
>gi|38570101 TBC1 domain family, member 8B (with GRAM domain)
isoform a [Homo sapiens]
Length = 1120
Score = 44.3 bits (103), Expect = 2e-04
Identities = 28/111 (25%), Positives = 59/111 (53%), Gaps = 3/111 (2%)
Query: 91 KANMHFHKLFLSVPTEEPLKQSFTCALQK-EILYQGKLFVSENWICFHSKVFGKDTKISI 149
+A + F K F +P +E L ++C+ K + QG L++S N++ F+S + G + K+ I
Sbjct: 142 EALLKFEKCF-GLPEKEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLII 200
Query: 150 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGH 200
V+ ++KT +L ++ + + + + F L + TY L++ + +
Sbjct: 201 SWDEVSKLEKTSNVILT-ESIHVCSQGENHYFSMFLHINQTYLLMEQLANY 250
Score = 35.4 bits (80), Expect = 0.096
Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)
Query: 91 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILY---QGKLFVSENWICFHSKVFGKDTKI 147
+A+ F +P E LK+ C L + GK+ +SEN+ICF S+ G +
Sbjct: 281 RAHSEQFNAFFRLPKGESLKEVHECFLWVPFSHFNTHGKMCISENYICFASQ-DGNQCSV 339
Query: 148 SIPAFSVTLIKKT 160
IP V I KT
Sbjct: 340 IIPLREVLAIDKT 352
>gi|67763814 death-inducing-protein [Homo sapiens]
Length = 578
Score = 37.7 bits (86), Expect = 0.019
Identities = 30/119 (25%), Positives = 59/119 (49%), Gaps = 18/119 (15%)
Query: 95 HFHKLFLSVPTEEPL---KQSFTCAL-------QKEILYQGKLFVSENWICFHSKVFG-- 142
+FH++F E PL + + C L + + G L+V+EN++CF S G
Sbjct: 446 NFHEIFNLTENERPLAVCENGWRCCLINRDRKMPTDYIRNGVLYVTENYLCFESSKSGSS 505
Query: 143 KDTKISIPAFSVTLIKKTKTALLVPNA---LIIATVTDR--YIFVSLLSRDSTYKLLKS 196
K K+ I +T I+K K ++P + + ++T + + +F +++ RD ++ + S
Sbjct: 506 KRNKV-IKLVDITDIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETILS 563
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 33.5 bits (75), Expect = 0.37
Identities = 31/110 (28%), Positives = 47/110 (42%), Gaps = 19/110 (17%)
Query: 12 SSEAENGVEEKKKACRSPTAQSPTPSVEA--DSPDQ----------KKIISLWSKSSFDG 59
S + E + KKK+CRS ++ S + S + DS D+ KK S S S
Sbjct: 88 SKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTH 147
Query: 60 ASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPL 109
S + K K + K+ +TE++K S K S P ++PL
Sbjct: 148 ESESESKESVKKKKKSKDETEKEKDVRSLSKKRKK-------SYPDDKPL 190
>gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]
Length = 753
Score = 33.1 bits (74), Expect = 0.48
Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 5/80 (6%)
Query: 15 AENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDC----K 70
A+ ++K C SP P+P D P + +S + G+S ++ + C +
Sbjct: 642 AKERASSRRKGCSSPPPPEPSPQA-PDGPSLQLPAQTFSSAPVPGSSSSTLPSSCEQSRQ 700
Query: 71 TESKNDPKTERKKSSSSSQY 90
E+ +DP+TE + S++
Sbjct: 701 AETPSDPQTETLSAMDVSEF 720
>gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens]
Length = 910
Score = 32.7 bits (73), Expect = 0.62
Identities = 29/144 (20%), Positives = 64/144 (44%), Gaps = 19/144 (13%)
Query: 138 SKVFGKDTKISIPAF--SVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSR----DSTY 191
S + G T+ ++ +F ++++I + + V N + ++ +SL S +ST
Sbjct: 312 SMIVGNATEAAVSSFVQNLSVIIRQNPSTTVGNLASVVSILSNISSLSLASHFRVSNSTM 371
Query: 192 KLLKSVCGHLENTSVGNSPNPSSAENSFRADR-------------PSSLPLDFNDEFSDL 238
+ + S+ ++ N++ + E + + R P++LPL+F+ +F D
Sbjct: 372 EDVISIADNILNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRKFIDW 431
Query: 239 DGVVQQRRQDMEGYSSSGSQTPES 262
G+ + Q GYS P++
Sbjct: 432 KGIPVNKSQLKRGYSYQIKMCPQN 455
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 32.3 bits (72), Expect = 0.81
Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 12 SSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKT 71
++ A EEKKK +S + S + K S S S D + +SD+ D K
Sbjct: 172 TTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDE-DNKR 230
Query: 72 ESKNDPKTERKKSSSSSQYK 91
+K K E+KK S +YK
Sbjct: 231 RAKKAKKKEKKKKHRSKKYK 250
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 32.0 bits (71), Expect = 1.1
Identities = 21/77 (27%), Positives = 35/77 (45%)
Query: 12 SSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKT 71
SS++ N + + S +++S S +DS S S SS +S +SD +D
Sbjct: 680 SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSN 739
Query: 72 ESKNDPKTERKKSSSSS 88
S + ++ SS SS
Sbjct: 740 SSDSSDSSDSSNSSDSS 756
Score = 30.8 bits (68), Expect = 2.4
Identities = 20/77 (25%), Positives = 33/77 (42%)
Query: 12 SSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKT 71
SSE+ + + + S ++ S S +DS D + S +S +SD +D
Sbjct: 1081 SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140
Query: 72 ESKNDPKTERKKSSSSS 88
S + +E SS SS
Sbjct: 1141 SSDSSDSSESSDSSDSS 1157
Score = 30.4 bits (67), Expect = 3.1
Identities = 19/77 (24%), Positives = 34/77 (44%)
Query: 12 SSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKT 71
SS++ N + + S ++ S S +DS D S+ +S +SD +D
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071
Query: 72 ESKNDPKTERKKSSSSS 88
S + ++ +SS SS
Sbjct: 1072 SSDSSDSSDSSESSDSS 1088
Score = 30.4 bits (67), Expect = 3.1
Identities = 19/77 (24%), Positives = 34/77 (44%)
Query: 12 SSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKT 71
SS++ N + + S ++ S S +DS D + S +S +SD +D
Sbjct: 1018 SSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1077
Query: 72 ESKNDPKTERKKSSSSS 88
S + ++ SS+SS
Sbjct: 1078 SSDSSESSDSSDSSNSS 1094
Score = 30.0 bits (66), Expect = 4.0
Identities = 18/76 (23%), Positives = 32/76 (42%)
Query: 12 SSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKT 71
SS++ N + + + S + S S +DS D + S+ +S +SD +D +
Sbjct: 914 SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973
Query: 72 ESKNDPKTERKKSSSS 87
+D S SS
Sbjct: 974 SDSSDSSNSSDSSDSS 989
Score = 29.6 bits (65), Expect = 5.3
Identities = 19/77 (24%), Positives = 33/77 (42%)
Query: 12 SSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKT 71
SS++ N + + S ++ S S +DS D S +S +SD +D
Sbjct: 1174 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNE 1233
Query: 72 ESKNDPKTERKKSSSSS 88
S + ++ SS+SS
Sbjct: 1234 SSDSSDSSDSSDSSNSS 1250
Score = 29.3 bits (64), Expect = 6.9
Identities = 18/77 (23%), Positives = 34/77 (44%)
Query: 12 SSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKT 71
SS++ + + + S ++ S S +DS D + S + +S +SD +D
Sbjct: 740 SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799
Query: 72 ESKNDPKTERKKSSSSS 88
S + ++ SS SS
Sbjct: 800 SSDSSNSSDSSDSSDSS 816
Score = 29.3 bits (64), Expect = 6.9
Identities = 19/77 (24%), Positives = 33/77 (42%)
Query: 12 SSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKT 71
SS++ N + + S ++ S S +DS D S+ +S +SD +D
Sbjct: 1135 SSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1194
Query: 72 ESKNDPKTERKKSSSSS 88
S + ++ SS SS
Sbjct: 1195 SSDSSDSSDSSDSSDSS 1211
Score = 28.9 bits (63), Expect = 9.0
Identities = 18/77 (23%), Positives = 34/77 (44%)
Query: 12 SSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKT 71
SS++ + + + S ++ S S +DS D + S +S +SD +D
Sbjct: 982 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041
Query: 72 ESKNDPKTERKKSSSSS 88
S + ++ SS+SS
Sbjct: 1042 SSDSSDSSDSSDSSNSS 1058
Score = 28.9 bits (63), Expect = 9.0
Identities = 18/78 (23%), Positives = 33/78 (42%)
Query: 12 SSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKT 71
SS++ + + + S ++ S S +DS D S +S +SD +D
Sbjct: 1006 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1065
Query: 72 ESKNDPKTERKKSSSSSQ 89
S + ++ SS SS+
Sbjct: 1066 SSDSSDSSDSSDSSDSSE 1083
Score = 28.9 bits (63), Expect = 9.0
Identities = 18/77 (23%), Positives = 33/77 (42%)
Query: 12 SSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKT 71
SS++ + + + S +++S S +DS D S +S +SD +D
Sbjct: 1129 SSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1188
Query: 72 ESKNDPKTERKKSSSSS 88
S + ++ SS SS
Sbjct: 1189 SSDSSDSSDSSDSSDSS 1205
Score = 28.9 bits (63), Expect = 9.0
Identities = 19/77 (24%), Positives = 33/77 (42%)
Query: 12 SSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKT 71
SS++ + E + S ++ S S +DS D + S +S +SD +D
Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1200
Query: 72 ESKNDPKTERKKSSSSS 88
S + ++ SS SS
Sbjct: 1201 SSDSSDSSDSSDSSDSS 1217
>gi|39995071 exonuclease 1 isoform b [Homo sapiens]
Length = 846
Score = 31.6 bits (70), Expect = 1.4
Identities = 26/95 (27%), Positives = 49/95 (51%), Gaps = 7/95 (7%)
Query: 199 GHLENTSVGNSPNPSSAENSFR--ADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYS-SS 255
G L + S SP+PS+A FR +D P+SLP + SD+ + + D E +
Sbjct: 613 GGLGDFSRTPSPSPSTALQQFRRKSDSPTSLP---ENNMSDVSQLKSEESSDDESHPLRE 669
Query: 256 GSQTPESENSRDFHATESQTVLNVSKGEAKPTRAD 290
G+ + +S+ S +F + +S +S+ +K + ++
Sbjct: 670 GACSSQSQESGEF-SLQSSNASKLSQCSSKDSDSE 703
>gi|39995069 exonuclease 1 isoform a [Homo sapiens]
Length = 803
Score = 31.6 bits (70), Expect = 1.4
Identities = 26/95 (27%), Positives = 49/95 (51%), Gaps = 7/95 (7%)
Query: 199 GHLENTSVGNSPNPSSAENSFR--ADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYS-SS 255
G L + S SP+PS+A FR +D P+SLP + SD+ + + D E +
Sbjct: 613 GGLGDFSRTPSPSPSTALQQFRRKSDSPTSLP---ENNMSDVSQLKSEESSDDESHPLRE 669
Query: 256 GSQTPESENSRDFHATESQTVLNVSKGEAKPTRAD 290
G+ + +S+ S +F + +S +S+ +K + ++
Sbjct: 670 GACSSQSQESGEF-SLQSSNASKLSQCSSKDSDSE 703
>gi|18491016 exonuclease 1 isoform b [Homo sapiens]
Length = 846
Score = 31.6 bits (70), Expect = 1.4
Identities = 26/95 (27%), Positives = 49/95 (51%), Gaps = 7/95 (7%)
Query: 199 GHLENTSVGNSPNPSSAENSFR--ADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYS-SS 255
G L + S SP+PS+A FR +D P+SLP + SD+ + + D E +
Sbjct: 613 GGLGDFSRTPSPSPSTALQQFRRKSDSPTSLP---ENNMSDVSQLKSEESSDDESHPLRE 669
Query: 256 GSQTPESENSRDFHATESQTVLNVSKGEAKPTRAD 290
G+ + +S+ S +F + +S +S+ +K + ++
Sbjct: 670 GACSSQSQESGEF-SLQSSNASKLSQCSSKDSDSE 703
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 31.6 bits (70), Expect = 1.4
Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)
Query: 14 EAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTES 73
E E V + R P A+ V A S K S S+SS + +S SD D +TE
Sbjct: 666 ELERYVTSCLRKKRKPQAEKV--DVIAGSSKMKGFSSSESESSSESSS--SDSEDSETEM 721
Query: 74 KNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEP 108
PK+++K Q K + H H+ P P
Sbjct: 722 A--PKSKKKGHPGREQKKHHHHHHQQMQQAPAPVP 754
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 31.6 bits (70), Expect = 1.4
Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 19/93 (20%)
Query: 14 EAENGVEEKK-----------KACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASL 62
EAE G EE K K +SP + EA SP++++ +KS + S
Sbjct: 493 EAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEE-----AKSPAEVKSP 547
Query: 63 ASDKNDCKTESKNDPKT---ERKKSSSSSQYKA 92
K+ K E+K+ P+ E++++ S ++ K+
Sbjct: 548 EKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKS 580
>gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]
Length = 861
Score = 31.6 bits (70), Expect = 1.4
Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 9/87 (10%)
Query: 27 RSPTAQSPTPSVEADSPDQKKIISLWSKSS-FDGASLASDKNDCKTESKNDPKTERKKSS 85
++P+A SP P+V SP K + SKSS S SD++ + K T SS
Sbjct: 599 KAPSAVSPIPAV-IPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSS 657
Query: 86 SSSQYKANMHFHKLFLSVPTEEPLKQS 112
SSS + + LS P P K++
Sbjct: 658 SSSSLQTS-------LSSPLSGPHKKN 677
>gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]
Length = 738
Score = 31.6 bits (70), Expect = 1.4
Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 9/87 (10%)
Query: 27 RSPTAQSPTPSVEADSPDQKKIISLWSKSS-FDGASLASDKNDCKTESKNDPKTERKKSS 85
++P+A SP P+V SP K + SKSS S SD++ + K T SS
Sbjct: 475 KAPSAVSPIPAV-IPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSS 533
Query: 86 SSSQYKANMHFHKLFLSVPTEEPLKQS 112
SSS + + LS P P K++
Sbjct: 534 SSSSLQTS-------LSSPLSGPHKKN 553
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 31.2 bits (69), Expect = 1.8
Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
Query: 5 KRFPFFFSSEAEN--GVEEKKKACRS-PTAQSPTPSVEADSPDQKK--IISLWSKSSFDG 59
++ PFFF AEN G+ E + A+ P P + D K +I W+K FDG
Sbjct: 27431 EKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDG 27490
Query: 60 ASLASD 65
S+ ++
Sbjct: 27491 GSVITE 27496
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,286,867
Number of Sequences: 37866
Number of extensions: 661904
Number of successful extensions: 2185
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 61
Number of HSP's that attempted gapping in prelim test: 2006
Number of HSP's gapped (non-prelim): 248
length of query: 416
length of database: 18,247,518
effective HSP length: 105
effective length of query: 311
effective length of database: 14,271,588
effective search space: 4438463868
effective search space used: 4438463868
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.