Search of human proteins with 226443011

Search of human proteins with 226443011

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens]
         (447 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens]        884   0.0  
gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens]        798   0.0  
gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens]        798   0.0  
gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens]        718   0.0  
gi|226443017 GRAM domain containing 3 isoform 3 [Homo sapiens]        647   0.0  
gi|60593095 GRAM domain containing 2 [Homo sapiens]                   140   2e-33
gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens]        106   5e-23
gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens]       105   1e-22
gi|144227752 GRAM domain containing 1B [Homo sapiens]                 100   3e-21
gi|187936935 GRAM domain containing 1C [Homo sapiens]                  97   2e-20
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho...    62   8e-10
gi|156231067 TBC1 domain family, member 8 [Homo sapiens]               54   2e-07
gi|45597177 TBC1 domain family, member 9B (with GRAM domain) iso...    49   1e-05
gi|45597175 TBC1 domain family, member 9B (with GRAM domain) iso...    49   1e-05
gi|38570103 TBC1 domain family, member 8B (with GRAM domain) iso...    44   2e-04
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso...    44   2e-04
gi|67763814 death-inducing-protein [Homo sapiens]                      38   0.021
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              34   0.24 
gi|168229156 NFKB activating protein [Homo sapiens]                    33   0.53 
gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]    33   0.53 
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    33   0.69 
gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens]    33   0.69 
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     32   0.90 
gi|126116565 MYC binding protein 2 [Homo sapiens]                      32   1.2  
gi|39995071 exonuclease 1 isoform b [Homo sapiens]                     32   1.5  
gi|39995069 exonuclease 1 isoform a [Homo sapiens]                     32   1.5  
gi|18491016 exonuclease 1 isoform b [Homo sapiens]                     32   1.5  
gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]         32   1.5  
gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]         32   1.5  
gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]                  32   1.5  

>gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens]
          Length = 447

 Score =  884 bits (2284), Expect = 0.0
 Identities = 447/447 (100%), Positives = 447/447 (100%)

Query: 1   MTRRQQVLQAKRSIQQTFQAQLMPWKSMFHGREVKPVGPDLELSEAENGVEEKKKACRSP 60
           MTRRQQVLQAKRSIQQTFQAQLMPWKSMFHGREVKPVGPDLELSEAENGVEEKKKACRSP
Sbjct: 1   MTRRQQVLQAKRSIQQTFQAQLMPWKSMFHGREVKPVGPDLELSEAENGVEEKKKACRSP 60

Query: 61  TAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQ 120
           TAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQ
Sbjct: 61  TAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQ 120

Query: 121 YKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISI 180
           YKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISI
Sbjct: 121 YKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISI 180

Query: 181 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNS 240
           PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNS
Sbjct: 181 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNS 240

Query: 241 PNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH 300
           PNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH
Sbjct: 241 PNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH 300

Query: 301 ATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHH 360
           ATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHH
Sbjct: 301 ATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHH 360

Query: 361 ILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEV 420
           ILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEV
Sbjct: 361 ILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEV 420

Query: 421 LCQELTANIVKLEKIQNNLQKLLENGD 447
           LCQELTANIVKLEKIQNNLQKLLENGD
Sbjct: 421 LCQELTANIVKLEKIQNNLQKLLENGD 447


>gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens]
          Length = 416

 Score =  798 bits (2061), Expect = 0.0
 Identities = 404/404 (100%), Positives = 404/404 (100%)

Query: 44  SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE 103
           SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE
Sbjct: 13  SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE 72

Query: 104 SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN 163
           SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN
Sbjct: 73  SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN 132

Query: 164 WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK 223
           WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK
Sbjct: 133 WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK 192

Query: 224 LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY 283
           LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY
Sbjct: 193 LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY 252

Query: 284 SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET 343
           SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET
Sbjct: 253 SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET 312

Query: 344 VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE 403
           VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE
Sbjct: 313 VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE 372

Query: 404 QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD 447
           QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD
Sbjct: 373 QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD 416


>gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens]
          Length = 432

 Score =  798 bits (2061), Expect = 0.0
 Identities = 404/404 (100%), Positives = 404/404 (100%)

Query: 44  SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE 103
           SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE
Sbjct: 29  SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE 88

Query: 104 SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN 163
           SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN
Sbjct: 89  SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN 148

Query: 164 WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK 223
           WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK
Sbjct: 149 WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK 208

Query: 224 LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY 283
           LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY
Sbjct: 209 LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY 268

Query: 284 SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET 343
           SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET
Sbjct: 269 SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET 328

Query: 344 VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE 403
           VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE
Sbjct: 329 VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE 388

Query: 404 QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD 447
           QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD
Sbjct: 389 QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD 432


>gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens]
          Length = 440

 Score =  718 bits (1854), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 84  SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS 143
           SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS
Sbjct: 77  SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS 136

Query: 144 FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII 203
           FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII
Sbjct: 137 FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII 196

Query: 204 ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN 263
           ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN
Sbjct: 197 ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN 256

Query: 264 DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH 323
           DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH
Sbjct: 257 DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH 316

Query: 324 VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI 383
           VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI
Sbjct: 317 VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI 376

Query: 384 NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL 443
           NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL
Sbjct: 377 NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL 436

Query: 444 ENGD 447
           ENGD
Sbjct: 437 ENGD 440


>gi|226443017 GRAM domain containing 3 isoform 3 [Homo sapiens]
          Length = 328

 Score =  647 bits (1669), Expect = 0.0
 Identities = 327/327 (100%), Positives = 327/327 (100%)

Query: 121 YKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISI 180
           YKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISI
Sbjct: 2   YKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISI 61

Query: 181 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNS 240
           PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNS
Sbjct: 62  PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNS 121

Query: 241 PNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH 300
           PNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH
Sbjct: 122 PNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH 181

Query: 301 ATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHH 360
           ATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHH
Sbjct: 182 ATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHH 241

Query: 361 ILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEV 420
           ILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEV
Sbjct: 242 ILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEV 301

Query: 421 LCQELTANIVKLEKIQNNLQKLLENGD 447
           LCQELTANIVKLEKIQNNLQKLLENGD
Sbjct: 302 LCQELTANIVKLEKIQNNLQKLLENGD 328


>gi|60593095 GRAM domain containing 2 [Homo sapiens]
          Length = 354

 Score =  140 bits (354), Expect = 2e-33
 Identities = 99/281 (35%), Positives = 140/281 (49%), Gaps = 20/281 (7%)

Query: 122 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIP 181
           K N  +HKLF  VP EE + +  +CALQ++ L QG+L++S NW+CFH+ +FGKD K+ IP
Sbjct: 69  KYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKVVIP 128

Query: 182 AFSVTLIKKTKTALLVPNALIIATVT-DRYIFVSLLSRDSTYKLLKSVCGHLENTSVGN- 239
             SV +IKK K A L+PN L I T T  +YIFVSLLSRDS Y LL+ VC HL+ +S  + 
Sbjct: 129 VVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSKKSL 188

Query: 240 -----SPNPSS-----AENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQ 289
                S  P S      E  +R   PSS  L   D        +     D         +
Sbjct: 189 SVREFSGEPESLEVLIPEMKWRKVCPSSRSLSLPDNIP----CIPPSSVDSTDSFFPSRK 244

Query: 290 TPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHK 349
            P SE SR   A+E+            P       N  P  K        L E      +
Sbjct: 245 PPMSEKSRAQVASENGGRWAWPMPGWGPACPKKMPNCSPTAKNAVYEEDELEEEPRSTGE 304

Query: 350 VKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQL 390
           ++       + +L  + +++C L++S+ Y+ +RI+ LE+QL
Sbjct: 305 LRLWD----YRLLKVFFVLICFLVMSSSYLAFRISRLEQQL 341


>gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens]
          Length = 724

 Score =  106 bits (264), Expect = 5e-23
 Identities = 60/164 (36%), Positives = 91/164 (55%), Gaps = 5/164 (3%)

Query: 67  PSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSS-----SSSQY 121
           PS     P+   ++   S SS +   +    +     S+N  +  +K  S     S +  
Sbjct: 28  PSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKKMQSWYSMLSPTYK 87

Query: 122 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIP 181
           + N  F KLF  +P  E L   ++CALQ+EIL QG+L++SENWICF+S +F  +T ISI 
Sbjct: 88  QRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQ 147

Query: 182 AFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 225
              VT +KK KTA L+PNA+ I T ++++ F S  +RD  + L+
Sbjct: 148 LKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLI 191


>gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens]
          Length = 713

 Score =  105 bits (261), Expect = 1e-22
 Identities = 59/159 (37%), Positives = 89/159 (55%), Gaps = 2/159 (1%)

Query: 67  PSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMH 126
           PS     P+   ++   S SS +   +    +     S+N  +  +  S +  Q   N  
Sbjct: 28  PSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKMLSPTYKQ--RNED 85

Query: 127 FHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVT 186
           F KLF  +P  E L   ++CALQ+EIL QG+L++SENWICF+S +F  +T ISI    VT
Sbjct: 86  FRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVT 145

Query: 187 LIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 225
            +KK KTA L+PNA+ I T ++++ F S  +RD  + L+
Sbjct: 146 CLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLI 184


>gi|144227752 GRAM domain containing 1B [Homo sapiens]
          Length = 738

 Score =  100 bits (248), Expect = 3e-21
 Identities = 59/173 (34%), Positives = 95/173 (54%), Gaps = 13/173 (7%)

Query: 62  AQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKN---DCKTESKNDPKTERKKSSS- 117
           ++SPTP     + D   ++   S  S D +    ++     C ++S        KKS S 
Sbjct: 28  SRSPTPQ----NQDGDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSGRSGGKNSKKSQSW 83

Query: 118 ----SSQYKA-NMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVF 172
               S  YK  N  F KLF  +P  E L   ++CALQ++IL QG+L++SENWICF+S +F
Sbjct: 84  YNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIF 143

Query: 173 GKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 225
             +T +++    +  + K KTA L+PNA+ + T ++++ F S  +RD TY ++
Sbjct: 144 RWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMMM 196


>gi|187936935 GRAM domain containing 1C [Homo sapiens]
          Length = 662

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 47/107 (43%), Positives = 71/107 (66%), Gaps = 1/107 (0%)

Query: 117 SSSQYK-ANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKD 175
           SSS YK  N  + + F  +P  E L   + CALQ++IL QG+L++SENW+CF+S +F  +
Sbjct: 60  SSSTYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWE 119

Query: 176 TKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTY 222
           T ISI   ++T + K KTA L+PNA+ I T ++++ F S  +RD +Y
Sbjct: 120 TTISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSY 166


>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
           sapiens]
          Length = 1266

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 38/125 (30%), Positives = 73/125 (58%), Gaps = 10/125 (8%)

Query: 105 KNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQK-EILYQGKLFVSEN 163
           K D  TE+ K       +A + FH+LF  +P EE L   ++C+  K ++  QG +++S N
Sbjct: 133 KEDDDTEKFK-------EAIVKFHRLF-GMPEEEKLVNYYSCSYWKGKVPRQGWMYLSIN 184

Query: 164 WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK 223
            +CF+S + G++ K+ I    +T ++K  T LL+P+ + ++T +  + F   L+ + T+K
Sbjct: 185 HLCFYSFLMGREAKLVIRWVDITQLEKNAT-LLLPDVIKVSTRSSEHFFSVFLNINETFK 243

Query: 224 LLKSV 228
           L++ +
Sbjct: 244 LMEQL 248



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/244 (20%), Positives = 107/244 (43%), Gaps = 33/244 (13%)

Query: 77  KKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPT 136
           +++ ++  +   D      D++  K + K+  K    K    ++ K+  +  +    +P 
Sbjct: 246 EQLANIAMRQLLDNEGFEQDRSLPKLKRKSPKKVSALKRDLDARAKSERY--RALFRLPK 303

Query: 137 EEPLKQSFTCALQ---KEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKT 193
           +E L     C L     ++   G++FVS N+ICF SK     + I IP   VT+++K  +
Sbjct: 304 DEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENLCSLI-IPLREVTIVEKADS 362

Query: 194 ALLVPNALIIATVTD-RYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRA 252
           + ++P+ L I+T     ++F +L  RD    L++ +   L+ T+           +   +
Sbjct: 363 SSVLPSPLSISTRNRMTFLFANLKDRDF---LVQRISDFLQQTT-----------SKIYS 408

Query: 253 DRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH------ATESQT 306
           D+      +F   ++  D  V  R   +   S   S + +++  R F+       T +QT
Sbjct: 409 DK------EFAGSYNSSDDEVYSRPSSLVSSSPQRSTSSDADGERQFNLNGNSVPTATQT 462

Query: 307 VLNV 310
           ++ +
Sbjct: 463 LMTM 466


>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
          Length = 1140

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 48/196 (24%), Positives = 91/196 (46%), Gaps = 23/196 (11%)

Query: 122 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILY---QGKLFVSENWICFHSKVFGKDTKI 178
           +A   F + F  +P +E L     C+L          G++F S+++ICF S+  G   KI
Sbjct: 281 RAQNEFFRAFFRLPRKEKLHAVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGC-CKI 339

Query: 179 SIPAFSVTLIKKTKTALLVPNALIIATVTD-RYIFVSLLSRDSTYKLLKSVCGHLENTSV 237
            +P   V  I+K +   L+P+ +I++  +   + F+ L  RDS   L++++   L+    
Sbjct: 340 ILPLREVVSIEKMEDTSLLPHPIIVSIRSKVAFQFIELRDRDS---LVEALLARLKQVHA 396

Query: 238 GNSPN-PSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDME--------------G 282
            +  +  +SA++   +    S  +  +  F DL+ +  Q  ++ E               
Sbjct: 397 NHPVHYDTSADDDMASLVFHSTSMCSDHRFGDLEMMSSQNSEESEKEKSPLMHPDALVTA 456

Query: 283 YSSSGSQTPESENSRD 298
           +  SGSQ+P+S  SR+
Sbjct: 457 FQQSGSQSPDSRMSRE 472



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 32/139 (23%), Positives = 66/139 (47%), Gaps = 12/139 (8%)

Query: 91  ASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQK 150
           A +A + +    E + +P+  R+   +  +++A  +F       P  E L   ++C   K
Sbjct: 120 ALIAEETSSRLAEQEEEPEKFRE---ALVKFEARFNF-------PEAEKLVTYYSCCCWK 169

Query: 151 -EILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDR 209
             +  QG L++S N +CF+S   GK+ K+ +P   +  +++T    L  + + I T    
Sbjct: 170 GRVPRQGWLYLSINHLCFYSFFLGKELKLVVPWVDIQKLERTSNVFLT-DTIRITTQNKE 228

Query: 210 YIFVSLLSRDSTYKLLKSV 228
             F   L+ D  +K+++ +
Sbjct: 229 RDFSMFLNLDEVFKVMEQL 247


>gi|45597177 TBC1 domain family, member 9B (with GRAM domain)
           isoform b [Homo sapiens]
          Length = 1233

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 36/155 (23%), Positives = 73/155 (47%), Gaps = 13/155 (8%)

Query: 75  DQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSV 134
           D ++ I+ + K    G  +A +  + + +   DP   ++         A +   K F  +
Sbjct: 102 DSEEDITTFVKGKIHGI-IAEENKNLQPQGDEDPGKFKE---------AELKMRKQF-GM 150

Query: 135 PTEEPLKQSFTCALQK-EILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKT 193
           P  E L   ++C+  K  +  QG L+++ N +CF+S + GK+  + +    +T ++K  T
Sbjct: 151 PEGEKLVNYYSCSYWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSLVVQWVDITRLEKNAT 210

Query: 194 ALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSV 228
            LL P ++ + T      F   L+   T+KL++ +
Sbjct: 211 -LLFPESIRVDTRDQELFFSMFLNIGETFKLMEQL 244



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 50/210 (23%), Positives = 94/210 (44%), Gaps = 33/210 (15%)

Query: 122 KANMHFHKLFLSVPTEEPLKQSFTCALQ---KEILYQGKLFVSENWICFHSKVFGKDTKI 178
           +A    ++    +P +E L    +C L     ++   G++F+S N+ICF SK       +
Sbjct: 284 RAKNECYRATFRLPRDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICFASKE-EDACHL 342

Query: 179 SIPAFSVTLIKKTKTALLVPNALIIATVTD-RYIFVSLLSRDSTYKLLKSVCGHLENT-- 235
            IP   VT+++K  ++ ++P+ L I+T +   ++F +L  RD    L++ +   L+ T  
Sbjct: 343 IIPLREVTIVEKADSSSVLPSPLSISTKSKMTFLFANLKDRDF---LVQRISDFLQKTPS 399

Query: 236 ----SVGN----------SPNPSSAENSFRADRPSSLPLDFNDEF------SDLDGVVQ- 274
               S+G+            +P+  E S +   P+S PL     F      +   G+++ 
Sbjct: 400 KQPGSIGSRKASVVDPSTESSPAPQEGSEQPASPAS-PLSSRQSFCAQEAPTASQGLLKL 458

Query: 275 -QRRQDMEGYSSSGSQTPESENSRDFHATE 303
            Q+   ME   + G++    E S   H  E
Sbjct: 459 FQKNSPMEDLGAKGAKEKMKEESWHIHFFE 488


>gi|45597175 TBC1 domain family, member 9B (with GRAM domain)
           isoform a [Homo sapiens]
          Length = 1250

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 36/155 (23%), Positives = 73/155 (47%), Gaps = 13/155 (8%)

Query: 75  DQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSV 134
           D ++ I+ + K    G  +A +  + + +   DP   ++         A +   K F  +
Sbjct: 102 DSEEDITTFVKGKIHGI-IAEENKNLQPQGDEDPGKFKE---------AELKMRKQF-GM 150

Query: 135 PTEEPLKQSFTCALQK-EILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKT 193
           P  E L   ++C+  K  +  QG L+++ N +CF+S + GK+  + +    +T ++K  T
Sbjct: 151 PEGEKLVNYYSCSYWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSLVVQWVDITRLEKNAT 210

Query: 194 ALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSV 228
            LL P ++ + T      F   L+   T+KL++ +
Sbjct: 211 -LLFPESIRVDTRDQELFFSMFLNIGETFKLMEQL 244



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 50/210 (23%), Positives = 94/210 (44%), Gaps = 33/210 (15%)

Query: 122 KANMHFHKLFLSVPTEEPLKQSFTCALQ---KEILYQGKLFVSENWICFHSKVFGKDTKI 178
           +A    ++    +P +E L    +C L     ++   G++F+S N+ICF SK       +
Sbjct: 284 RAKNECYRATFRLPRDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICFASKE-EDACHL 342

Query: 179 SIPAFSVTLIKKTKTALLVPNALIIATVTD-RYIFVSLLSRDSTYKLLKSVCGHLENT-- 235
            IP   VT+++K  ++ ++P+ L I+T +   ++F +L  RD    L++ +   L+ T  
Sbjct: 343 IIPLREVTIVEKADSSSVLPSPLSISTKSKMTFLFANLKDRDF---LVQRISDFLQKTPS 399

Query: 236 ----SVGN----------SPNPSSAENSFRADRPSSLPLDFNDEF------SDLDGVVQ- 274
               S+G+            +P+  E S +   P+S PL     F      +   G+++ 
Sbjct: 400 KQPGSIGSRKASVVDPSTESSPAPQEGSEQPASPAS-PLSSRQSFCAQEAPTASQGLLKL 458

Query: 275 -QRRQDMEGYSSSGSQTPESENSRDFHATE 303
            Q+   ME   + G++    E S   H  E
Sbjct: 459 FQKNSPMEDLGAKGAKEKMKEESWHIHFFE 488


>gi|38570103 TBC1 domain family, member 8B (with GRAM domain)
           isoform b [Homo sapiens]
          Length = 632

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 28/111 (25%), Positives = 59/111 (53%), Gaps = 3/111 (2%)

Query: 122 KANMHFHKLFLSVPTEEPLKQSFTCALQK-EILYQGKLFVSENWICFHSKVFGKDTKISI 180
           +A + F K F  +P +E L   ++C+  K  +  QG L++S N++ F+S + G + K+ I
Sbjct: 142 EALLKFEKCF-GLPEKEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLII 200

Query: 181 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGH 231
               V+ ++KT   +L   ++ + +  + + F   L  + TY L++ +  +
Sbjct: 201 SWDEVSKLEKTSNVILT-ESIHVCSQGENHYFSMFLHINQTYLLMEQLANY 250



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)

Query: 122 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILY---QGKLFVSENWICFHSKVFGKDTKI 178
           +A+      F  +P  E LK+   C L     +    GK+ +SEN+ICF S+  G    +
Sbjct: 281 RAHSEQFNAFFRLPKGESLKEVHECFLWVPFSHFNTHGKMCISENYICFASQ-DGNQCSV 339

Query: 179 SIPAFSVTLIKKT 191
            IP   V  I KT
Sbjct: 340 IIPLREVLAIDKT 352


>gi|38570101 TBC1 domain family, member 8B (with GRAM domain)
           isoform a [Homo sapiens]
          Length = 1120

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 28/111 (25%), Positives = 59/111 (53%), Gaps = 3/111 (2%)

Query: 122 KANMHFHKLFLSVPTEEPLKQSFTCALQK-EILYQGKLFVSENWICFHSKVFGKDTKISI 180
           +A + F K F  +P +E L   ++C+  K  +  QG L++S N++ F+S + G + K+ I
Sbjct: 142 EALLKFEKCF-GLPEKEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLII 200

Query: 181 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGH 231
               V+ ++KT   +L   ++ + +  + + F   L  + TY L++ +  +
Sbjct: 201 SWDEVSKLEKTSNVILT-ESIHVCSQGENHYFSMFLHINQTYLLMEQLANY 250



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)

Query: 122 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILY---QGKLFVSENWICFHSKVFGKDTKI 178
           +A+      F  +P  E LK+   C L     +    GK+ +SEN+ICF S+  G    +
Sbjct: 281 RAHSEQFNAFFRLPKGESLKEVHECFLWVPFSHFNTHGKMCISENYICFASQ-DGNQCSV 339

Query: 179 SIPAFSVTLIKKT 191
            IP   V  I KT
Sbjct: 340 IIPLREVLAIDKT 352


>gi|67763814 death-inducing-protein [Homo sapiens]
          Length = 578

 Score = 37.7 bits (86), Expect = 0.021
 Identities = 30/119 (25%), Positives = 59/119 (49%), Gaps = 18/119 (15%)

Query: 126 HFHKLFLSVPTEEPL---KQSFTCAL-------QKEILYQGKLFVSENWICFHSKVFG-- 173
           +FH++F     E PL   +  + C L         + +  G L+V+EN++CF S   G  
Sbjct: 446 NFHEIFNLTENERPLAVCENGWRCCLINRDRKMPTDYIRNGVLYVTENYLCFESSKSGSS 505

Query: 174 KDTKISIPAFSVTLIKKTKTALLVPNA---LIIATVTDR--YIFVSLLSRDSTYKLLKS 227
           K  K+ I    +T I+K K   ++P +   + ++T + +   +F +++ RD  ++ + S
Sbjct: 506 KRNKV-IKLVDITDIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETILS 563


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 34.3 bits (77), Expect = 0.24
 Identities = 34/127 (26%), Positives = 52/127 (40%), Gaps = 19/127 (14%)

Query: 26  KSMFHGREVKPVGPDLELSEAENGVEEKKKACRSPTAQSPTPSVEA--DSPDQ------- 76
           K +   RE    G +    + E   + KKK+CRS ++ S + S  +  DS D+       
Sbjct: 71  KELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKR 130

Query: 77  ---KKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLS 133
              KK  S  S  S    S +  K   K + K+  +TE++K   S   K          S
Sbjct: 131 RKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKK-------S 183

Query: 134 VPTEEPL 140
            P ++PL
Sbjct: 184 YPDDKPL 190


>gi|168229156 NFKB activating protein [Homo sapiens]
          Length = 415

 Score = 33.1 bits (74), Expect = 0.53
 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 1/84 (1%)

Query: 39  PDLELSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKN 98
           P    + A    EEKKK       +S     +  S  + K  S  S S  D  + +SD+ 
Sbjct: 168 PKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDE- 226

Query: 99  DCKTESKNDPKTERKKSSSSSQYK 122
           D K  +K   K E+KK   S +YK
Sbjct: 227 DNKRRAKKAKKKEKKKKHRSKKYK 250


>gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]
          Length = 753

 Score = 33.1 bits (74), Expect = 0.53
 Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 5/80 (6%)

Query: 46  AENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDC----K 101
           A+     ++K C SP    P+P    D P  +     +S +   G+S ++  + C    +
Sbjct: 642 AKERASSRRKGCSSPPPPEPSPQA-PDGPSLQLPAQTFSSAPVPGSSSSTLPSSCEQSRQ 700

Query: 102 TESKNDPKTERKKSSSSSQY 121
            E+ +DP+TE   +   S++
Sbjct: 701 AETPSDPQTETLSAMDVSEF 720


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 32.7 bits (73), Expect = 0.69
 Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 6/97 (6%)

Query: 43  LSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKT 102
           L E E  V    +  R P A+     V A S   K   S  S+SS + +S  SD  D +T
Sbjct: 664 LRELERYVTSCLRKKRKPQAEKV--DVIAGSSKMKGFSSSESESSSESSS--SDSEDSET 719

Query: 103 ESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEP 139
           E    PK+++K      Q K + H H+     P   P
Sbjct: 720 EMA--PKSKKKGHPGREQKKHHHHHHQQMQQAPAPVP 754


>gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens]
          Length = 910

 Score = 32.7 bits (73), Expect = 0.69
 Identities = 29/144 (20%), Positives = 64/144 (44%), Gaps = 19/144 (13%)

Query: 169 SKVFGKDTKISIPAF--SVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSR----DSTY 222
           S + G  T+ ++ +F  ++++I +   +  V N   + ++      +SL S     +ST 
Sbjct: 312 SMIVGNATEAAVSSFVQNLSVIIRQNPSTTVGNLASVVSILSNISSLSLASHFRVSNSTM 371

Query: 223 KLLKSVCGHLENTSVGNSPNPSSAENSFRADR-------------PSSLPLDFNDEFSDL 269
           + + S+  ++ N++   +      E  + + R             P++LPL+F+ +F D 
Sbjct: 372 EDVISIADNILNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRKFIDW 431

Query: 270 DGVVQQRRQDMEGYSSSGSQTPES 293
            G+   + Q   GYS      P++
Sbjct: 432 KGIPVNKSQLKRGYSYQIKMCPQN 455


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 32.3 bits (72), Expect = 0.90
 Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 19/96 (19%)

Query: 42  ELSEAENGVEEKK-----------KACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDG 90
           E  EAE G EE K           K  +SP  +      EA SP++++     +KS  + 
Sbjct: 490 EEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEE-----AKSPAEV 544

Query: 91  ASLASDKNDCKTESKNDPKT---ERKKSSSSSQYKA 123
            S    K+  K E+K+ P+    E++++ S ++ K+
Sbjct: 545 KSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKS 580


>gi|126116565 MYC binding protein 2 [Homo sapiens]
          Length = 4640

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 19/123 (15%)

Query: 43   LSEAENGVEEKKKACRSPT---AQSPTPSVEADSPDQKKIISLWSKSSFDGASL------ 93
            LS   N ++  K   R P+   A+SP P     SP  K + +  ++SS  GAS       
Sbjct: 2750 LSPNHNTLQTLKSDGRMPSSSRAESPGPGSRLSSPKPKTLPA--NRSSPSGASSPRSSSP 2807

Query: 94   ----ASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQ 149
                   K+    ++K DP  ER KS S +     +   K+    P  EPL+   T    
Sbjct: 2808 HDKNLPQKSTAPVKTKLDPPRERSKSDSYTLDPDTLRKKKM----PLTEPLRGRSTSPKP 2863

Query: 150  KEI 152
            K +
Sbjct: 2864 KSV 2866


>gi|39995071 exonuclease 1 isoform b [Homo sapiens]
          Length = 846

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 26/95 (27%), Positives = 49/95 (51%), Gaps = 7/95 (7%)

Query: 230 GHLENTSVGNSPNPSSAENSFR--ADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYS-SS 286
           G L + S   SP+PS+A   FR  +D P+SLP    +  SD+  +  +   D E +    
Sbjct: 613 GGLGDFSRTPSPSPSTALQQFRRKSDSPTSLP---ENNMSDVSQLKSEESSDDESHPLRE 669

Query: 287 GSQTPESENSRDFHATESQTVLNVSKGEAKPTRAD 321
           G+ + +S+ S +F + +S     +S+  +K + ++
Sbjct: 670 GACSSQSQESGEF-SLQSSNASKLSQCSSKDSDSE 703


>gi|39995069 exonuclease 1 isoform a [Homo sapiens]
          Length = 803

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 26/95 (27%), Positives = 49/95 (51%), Gaps = 7/95 (7%)

Query: 230 GHLENTSVGNSPNPSSAENSFR--ADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYS-SS 286
           G L + S   SP+PS+A   FR  +D P+SLP    +  SD+  +  +   D E +    
Sbjct: 613 GGLGDFSRTPSPSPSTALQQFRRKSDSPTSLP---ENNMSDVSQLKSEESSDDESHPLRE 669

Query: 287 GSQTPESENSRDFHATESQTVLNVSKGEAKPTRAD 321
           G+ + +S+ S +F + +S     +S+  +K + ++
Sbjct: 670 GACSSQSQESGEF-SLQSSNASKLSQCSSKDSDSE 703


>gi|18491016 exonuclease 1 isoform b [Homo sapiens]
          Length = 846

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 26/95 (27%), Positives = 49/95 (51%), Gaps = 7/95 (7%)

Query: 230 GHLENTSVGNSPNPSSAENSFR--ADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYS-SS 286
           G L + S   SP+PS+A   FR  +D P+SLP    +  SD+  +  +   D E +    
Sbjct: 613 GGLGDFSRTPSPSPSTALQQFRRKSDSPTSLP---ENNMSDVSQLKSEESSDDESHPLRE 669

Query: 287 GSQTPESENSRDFHATESQTVLNVSKGEAKPTRAD 321
           G+ + +S+ S +F + +S     +S+  +K + ++
Sbjct: 670 GACSSQSQESGEF-SLQSSNASKLSQCSSKDSDSE 703


>gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]
          Length = 1251

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 8/100 (8%)

Query: 40  DLELSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKND 99
           DL+LS  E   E +++A +    ++ + S     P+ +  +   SK S   +S  S  + 
Sbjct: 394 DLKLSSDEE--ENEQQAAQRTALRALSDSAVVQQPNCRTSVPS-SKGSSSSSSSGSSSSS 450

Query: 100 CKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEP 139
             +ES +   +E + SSS S+     HF     S P  EP
Sbjct: 451 SDSESSSGSDSETESSSSESEGSKPPHF-----SSPEAEP 485


>gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]
          Length = 1226

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 8/100 (8%)

Query: 40  DLELSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKND 99
           DL+LS  E   E +++A +    ++ + S     P+ +  +   SK S   +S  S  + 
Sbjct: 369 DLKLSSDEE--ENEQQAAQRTALRALSDSAVVQQPNCRTSVPS-SKGSSSSSSSGSSSSS 425

Query: 100 CKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEP 139
             +ES +   +E + SSS S+     HF     S P  EP
Sbjct: 426 SDSESSSGSDSETESSSSESEGSKPPHF-----SSPEAEP 460


>gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]
          Length = 861

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 9/87 (10%)

Query: 58  RSPTAQSPTPSVEADSPDQKKIISLWSKSS-FDGASLASDKNDCKTESKNDPKTERKKSS 116
           ++P+A SP P+V   SP  K   +  SKSS     S  SD++    + K    T    SS
Sbjct: 599 KAPSAVSPIPAV-IPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSS 657

Query: 117 SSSQYKANMHFHKLFLSVPTEEPLKQS 143
           SSS  + +       LS P   P K++
Sbjct: 658 SSSSLQTS-------LSSPLSGPHKKN 677


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.128    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,433,228
Number of Sequences: 37866
Number of extensions: 726232
Number of successful extensions: 2448
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 63
Number of HSP's that attempted gapping in prelim test: 2284
Number of HSP's gapped (non-prelim): 235
length of query: 447
length of database: 18,247,518
effective HSP length: 105
effective length of query: 342
effective length of database: 14,271,588
effective search space: 4880883096
effective search space used: 4880883096
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.